format-version: 1.2
data-version: releases/2026-07-28
subsetdef: mrex "medically relevant exposure"
idspace: dc http://purl.org/dc/elements/1.1/ 
idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# 
idspace: terms http://purl.org/dc/terms/ 
ontology: ecto
property_value: dc:description "ECTO describes exposures to experimental treatments of plants and model organisms (e.g. exposures to modification of diet, lighting levels, temperature); exposures of humans or any other organisms to stressors through a variety of routes, for purposes of public health, environmental monitoring etc, stimuli, natural and experimental, any kind of environmental condition or change in condition that can be experienced by an organism or population of organisms on earth. The scope is very general and can include for example plant treatment regimens, as well as human clinical exposures (although these may better be handled by a more specialized ontology)." xsd:string
property_value: dc:title "Environment Exposure Ontology" xsd:string
property_value: IAO:0000700 "http://purl.obolibrary.org/obo/ExO_0000002" xsd:string
property_value: owl:versionInfo "2026-07-28" xsd:string
property_value: terms:license https://creativecommons.org/publicdomain/zero/1.0/

[Term]
id: BFO:0000001
name: entity

[Term]
id: BFO:0000002
name: continuant
is_a: BFO:0000001 ! entity
disjoint_from: BFO:0000003 ! occurrent
relationship: BFO:0000050 BFO:0000002 {all_only="true"} ! part of continuant

[Term]
id: BFO:0000003
name: occurrent
is_a: BFO:0000001 ! entity
relationship: BFO:0000050 BFO:0000003 {all_only="true"} ! part of occurrent

[Term]
id: BFO:0000004
name: independent continuant
is_a: BFO:0000002 ! continuant
disjoint_from: BFO:0000020 ! specifically dependent continuant
relationship: BFO:0000050 BFO:0000004 {all_only="true"} ! part of independent continuant

[Term]
id: BFO:0000006
name: spatial region
is_a: BFO:0000141 ! immaterial entity

[Term]
id: BFO:0000015
name: process
is_a: BFO:0000003 ! occurrent

[Term]
id: BFO:0000016
name: disposition
is_a: BFO:0000017 ! realizable entity
disjoint_from: BFO:0000023 ! role

[Term]
id: BFO:0000017
name: realizable entity
is_a: BFO:0000020 ! specifically dependent continuant
disjoint_from: BFO:0000019 ! quality
relationship: BFO:0000050 BFO:0000017 {all_only="true"} ! part of realizable entity

[Term]
id: BFO:0000019
name: quality
is_a: BFO:0000020 ! specifically dependent continuant
relationship: BFO:0000050 BFO:0000019 {all_only="true"} ! part of quality

[Term]
id: BFO:0000020
name: specifically dependent continuant
is_a: BFO:0000002 ! continuant
relationship: BFO:0000050 BFO:0000020 {all_only="true"} ! part of specifically dependent continuant

[Term]
id: BFO:0000023
name: role
is_a: BFO:0000017 ! realizable entity

[Term]
id: BFO:0000024
name: fiat object part
is_a: BFO:0000040 ! material entity

[Term]
id: BFO:0000027
name: object aggregate
is_a: BFO:0000040 ! material entity

[Term]
id: BFO:0000030
name: object
is_a: BFO:0000040 ! material entity

[Term]
id: BFO:0000034
name: function
is_a: BFO:0000016 ! disposition

[Term]
id: BFO:0000040
name: material entity
is_a: BFO:0000004 ! independent continuant
disjoint_from: BFO:0000141 ! immaterial entity

[Term]
id: BFO:0000141
name: immaterial entity
is_a: BFO:0000004 ! independent continuant

[Term]
id: CHEBI:10022
name: deoxynivalenol
def: "A trichothecene mycotoxin produced by <em>Fusarium</em> to which wheat, barley, maize (corn) and their products are susceptible to contamination." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:2468 ! secondary alpha-hydroxy ketone
is_a: CHEBI:27136 ! triol
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:51689 ! enone
is_a: CHEBI:55517 ! trichothecene

[Term]
id: CHEBI:10023
name: voriconazole
def: "A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by <em>Scedosporium apiospermum</em> and <em>Fusarium</em> spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:38582 ! difluorobenzene
is_a: CHEBI:38976 ! alkylbenzene
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:87071 ! conazole antifungal drug
is_a: CHEBI:87101 ! triazole antifungal drug
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50183 ! has role P450 inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent

[Term]
id: CHEBI:100241
name: ciprofloxacin
def: "A  quinolone that is quinolin-4(1<em>H</em>)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively." []
is_a: CHEBI:23765 ! quinolone
is_a: CHEBI:26512 ! quinolinemonocarboxylic acid
is_a: CHEBI:36709 ! aminoquinoline
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:86324 ! quinolone antibiotic
is_a: CHEBI:87211 ! fluoroquinolone antibiotic
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:53559 ! has role topoisomerase IV inhibitor
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:192486 ! is deprotonated form of ciprofloxacin(1+)
relationship: RO:0018036 CHEBI:192484 ! is tautomer of ciprofloxacin zwitterion

[Term]
id: CHEBI:100246
name: norfloxacin
def: "A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase." []
is_a: CHEBI:23765 ! quinolone
is_a: CHEBI:26512 ! quinolinemonocarboxylic acid
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:86324 ! quinolone antibiotic
is_a: CHEBI:87211 ! fluoroquinolone antibiotic
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:10033
name: warfarin
def: "A racemate comprising equal amounts of (<i>R</i>)- and (<i>S</i>)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:87737 ! has part (R)-warfarin
relationship: BFO:0000051 CHEBI:87738 ! has part (S)-warfarin
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33288 ! has role rodenticide
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50390 ! has role EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:55347 ! has role vitamin K antagonist
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018034 CHEBI:50393 ! is protonated form of warfarin(1-)

[Term]
id: CHEBI:10093
name: yohimbine
def: "An indole alkaloid with α<small><sub>2</sub></small>-adrenoceptor antagonist activity. It is produced by <em>Corynanthe johimbe</em> and <em>Rauwolfia serpentina</em>." []
is_a: CHEBI:48565 ! methyl 17-hydroxy-20xi-yohimban-16-carboxylate
relationship: RO:0000087 CHEBI:131787 ! has role dopamine receptor D2 antagonist
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0018038 CHEBI:35633 ! has functional parent yohimbic acid

[Term]
id: CHEBI:10106
name: zearalenone
def: "A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some <em>Giberella</em> species." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25106 ! macrolide
is_a: CHEBI:33572 ! resorcinols
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:76990 ! has role mycoestrogen

[Term]
id: CHEBI:10112
name: zileuton
def: "A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38836 ! 1-benzothiophenes
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:49159 ! has role leukotriene antagonist
relationship: RO:0000087 CHEBI:49167 ! has role anti-asthmatic drug
relationship: RO:0000087 CHEBI:64964 ! has role EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018040 CHEBI:35858 ! has parent hydride 1-benzothiophene

[Term]
id: CHEBI:10119
name: ziprasidone
def: "A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms." []
is_a: CHEBI:24829 ! indolones
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:55505 ! 1,2-benzisothiazole
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:37956 ! has role histamine antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:48876 ! has role muscarinic antagonist

[Term]
id: CHEBI:10127
name: zonisamide
def: "A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:51545 ! 1,2-benzoxazoles
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:194338 ! has role T-type calcium channel blocker
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50267 ! has role protective agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:101278
name: diltiazem
def: "A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have <i>S</i> configuration. A calcium-channel blocker and vasodilator, it is used as the hydrochloride in the management of angina pectoris and hypertension." []
is_a: CHEBI:82814 ! 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0018033 CHEBI:82812 ! is deprotonated form of diltiazem(1+)
relationship: RO:0018039 CHEBI:82813 ! is enantiomer of ent-diltiazem

[Term]
id: CHEBI:102166
name: thiopental
def: "A barbiturate, the structure of which is that of 2-thiobarbituric acid substituted at C-5 by ethyl and <em>sec</em>-pentyl groups." []
is_a: CHEBI:22693 ! barbiturates
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35717 ! has role sedative
relationship: RO:0000087 CHEBI:38877 ! has role intravenous anaesthetic
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:61485 ! is protonated form of thiopental(1-)
relationship: RO:0018038 CHEBI:33202 ! has functional parent 2-thiobarbituric acid

[Term]
id: CHEBI:102248
name: EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
def: "An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29)." []
is_a: CHEBI:76902 ! EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor

[Term]
id: CHEBI:102265
name: sulfamethazine
def: "A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position." []
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:87228 ! sulfonamide antibiotic
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:50502 ! has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:52214 ! has role ligand
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:45373 ! has functional parent sulfanilamide

[Term]
id: CHEBI:10319
name: 1-naphthol
def: "A naphthol carrying a hydroxy group at position 1." []
is_a: CHEBI:35682 ! naphthol
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite

[Term]
id: CHEBI:10432
name: 2-naphthol
def: "A naphthol carrying a hydroxy group at position 2." []
is_a: CHEBI:35682 ! naphthol
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite

[Term]
id: CHEBI:10436
name: beta-ocimene
def: "The <i>trans</i>-stereoisomer of ocimene." []
is_a: CHEBI:87751 ! ocimene

[Term]
id: CHEBI:10545
name: electron
def: "Elementary particle not affected by the strong force having a spin ½, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." []
is_a: CHEBI:36338 ! lepton

[Term]
id: CHEBI:10565
name: gamma-glutamyl-beta-cyanoalanine
def: "A dipeptide composed of 3-cyano-<small>L</small>-alanine and <small>L</small>-glutamine joined by a peptide linkage formed from the side-chain of glutamine." []
is_a: CHEBI:46761 ! dipeptide
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018038 CHEBI:16934 ! has functional parent 3-cyano-L-alanine
relationship: RO:0018038 CHEBI:18050 ! has functional parent L-glutamine

[Term]
id: CHEBI:10588
name: 1-(3-chlorophenyl)piperazine
def: "A <em>N</em>-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone." []
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35941 ! has role serotonergic agonist
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:10589
name: m-toluic acid
def: "A methylbenzoic acid carrying a methyl substituent at position 3." []
is_a: CHEBI:25280 ! methylbenzoic acid
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:28795 ! is protonated form of m-toluate

[Term]
id: CHEBI:10615
name: omega-hydroxy fatty acid
def: "Any member of the class of naturally-occurring straight-chain fatty acids n carbon atoms long with a carboxyl group at position 1 and a hydroxyl at position n (ω)." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:24654 ! hydroxy fatty acid
relationship: RO:0018034 CHEBI:76307 ! is protonated form of omega-hydroxy fatty acid anion

[Term]
id: CHEBI:10642
name: scyllo-inositol
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23480 ! cyclohexanols
is_a: CHEBI:24848 ! inositol
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:107736
name: metoclopramide
def: "A member of the class of  benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of <em>N</em>,<em>N</em>-diethylethane-1,2-diamine." []
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:36586 ! carbonyl compound
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:76916 ! has role hyperglycemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:61170 ! is deprotonated form of metoclopramide(1+)

[Term]
id: CHEBI:109895
name: beta-carboline
def: "The parent compound of the β-carbolines, a tricyclic structure comprising an indole ring system <em>ortho</em>- fused to C-3 and C-4 of a pyridine ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36416 ! mancude organic heterotricyclic parent
is_a: CHEBI:60834 ! beta-carbolines
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite

[Term]
id: CHEBI:113451
name: sodium ascorbate
def: "An organic sodium salt resulting from the replacement of the proton from the 3-hydroxy group of ascorbic acid by a sodium ion." []
is_a: CHEBI:176783 ! vitamin C
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:38290 ! has part L-ascorbate
relationship: RO:0000087 CHEBI:23354 ! has role coenzyme
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:63247 ! has role reducing agent
relationship: RO:0000087 CHEBI:64577 ! has role flour treatment agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:77962 ! has role food antioxidant
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite

[Term]
id: CHEBI:113455
name: sodium benzoate
def: "An organic sodium salt resulting from the replacement of the proton from the carboxy group of benzoic acid by a sodium ion." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:16150 ! has part benzoate
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:64996 ! has role EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
relationship: RO:0000087 CHEBI:65001 ! has role EC 3.1.1.3 (triacylglycerol lipase) inhibitor
relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:114785
name: erlotinib
def: "A quinazoline compound having a (3-ethynylphenyl)amino group at the 4-position and two 2-methoxyethoxy groups at the 6- and 7-positions." []
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38530 ! quinazolines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:73477 ! terminal acetylenic compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:74440 ! has role epidermal growth factor receptor antagonist

[Term]
id: CHEBI:115196
name: 2-hydroxybenzothiazole
def: "Benzothiazole substituted with a hydroxy group at the 2-position." []
is_a: CHEBI:37947 ! benzothiazoles

[Term]
id: CHEBI:11596
name: 2-hydroxyglutarate(2-)
def: "A dicarboxylic acid dianion resulting from the removal of a proton from both of the carboxylic acid groups of 2-hydroxyglutaric acid." []
is_a: CHEBI:132941 ! 2-hydroxyglutarate
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0018033 CHEBI:36149 ! is deprotonated form of 2-hydroxyglutarate(1-)
relationship: RO:0018038 CHEBI:30921 ! has functional parent glutarate(2-)

[Term]
id: CHEBI:116314
name: oleamide
def: "A fatty amide derived from oleic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:143129 ! primary fatty amide
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:116509
name: diuron
def: "A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:157693 ! 3-(3,4-substituted-phenyl)-1,1-dimethylurea
is_a: CHEBI:23697 ! dichlorobenzene
relationship: RO:0000087 CHEBI:188147 ! has role urea herbicide
relationship: RO:0000087 CHEBI:25355 ! has role mitochondrial respiratory-chain inhibitor
relationship: RO:0000087 CHEBI:26089 ! has role photosystem-II inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:119486
name: efavirenz
def: "1,4-Dihydro-2<em>H</em>-3,1-benzoxazin-2-one substituted at the 4 position by cyclopropylethynyl and trifluoromethyl groups (<i>S</i> configuration) and at the 6 position by chlorine. A non-nucleoside reverse transcriptase inhibitor with activity against HIV, it is used with other antiretrovirals for combination therapy of HIV infection." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:46969 ! benzoxazine
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:73474 ! acetylenic compound
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor

[Term]
id: CHEBI:11955
name: 4-amino-3-hydroxybutanoate
def: "The conjugate base of γ-amino-β-hydroxybutyric acid arising from deprotonation of the carboxy group." []
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
is_a: CHEBI:71666 ! gamma-amino acid anion
relationship: RO:0018033 CHEBI:16080 ! is deprotonated form of gamma-amino-beta-hydroxybutyric acid
relationship: RO:0018033 CHEBI:57630 ! is deprotonated form of gamma-amino-beta-hydroxybutyric acid zwitterion
relationship: RO:0018038 CHEBI:17968 ! has functional parent butyrate

[Term]
id: CHEBI:119915
name: fentanyl
def: "A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of <em>N</em>-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13248 ! anilide
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:29347 ! monocarboxylic acid amide
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38877 ! has role intravenous anaesthetic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:60807 ! has role anaesthesia adjuvant
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:12109
name: 5-aminolevulinate
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:17549 ! is deprotonated form of 5-aminolevulinic acid
relationship: RO:0018038 CHEBI:39150 ! has functional parent 4-oxopentanoate

[Term]
id: CHEBI:1224
name: 2-nitrofluorene
def: "A nitroarene that is  fluorene substituted by a nitro group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51132 ! nitroarene
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018038 CHEBI:28266 ! has functional parent fluorene

[Term]
id: CHEBI:127342
name: atomoxetine
def: "A  secondary amino compound having methyl and 3-(2-methylphenoxy)-3-phenylpropan-1-yl substituents." []
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:12777
name: vitamin A
def: "Any member of a group of fat-soluble retinoids produced via metabolism of provitamin A carotenoids that exhibit biological activity against vitamin A deficiency. Vitamin A is involved in immune function, vision, reproduction, and cellular communication." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26537 ! retinoid
relationship: RO:0000087 CHEBI:24020 ! has role fat-soluble vitamin (role)
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:12936
name: D-galactose
is_a: CHEBI:17608 ! D-aldohexose
is_a: CHEBI:28260 ! galactose
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:131174
name: navitoclax
def: "A <em>N</em>-sulfonylcarboxamide resulting from the formal condensation of the carboxy group of 4-{4-[(4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro[biphenyl]-2-yl)methyl]piperazin-1-yl}benzoic acid with the amino group of 4-{[(2<i>R</i>)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]benzenesulfonamide. It is a BH3-mimetic drug which targets the anti-apoptotic B-cell lymphoma-2 (BCL-2) family proteins, including BCL-2, BCL-xL, and BCL-w, and induces apoptosis in cancer cells. Currently under clinical investigation as treatment for solid tumors and hematologic malignancies." []
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:35850 ! sulfone
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:90852 ! N-sulfonylcarboxamide
relationship: RO:0000087 CHEBI:133022 ! has role B-cell lymphoma 2 inhibitor
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:131401
name: hexopyranosyl hexopyranoside
def: "A disaccharide formed by a (1↔1)-glycosidic bond between two hexopyranose units." []
is_a: CHEBI:24407 ! glycosyl glycoside

[Term]
id: CHEBI:131444
name: guanidinoacetate
def: "A monocarboxylic acid anion that is the conjugate base of guanidinoacetic acid, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:16344 ! is deprotonated form of guanidinoacetic acid

[Term]
id: CHEBI:131565
name: steroid aldehyde
def: "Any steroid substituted by a formyl group." []
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:131604
name: Mycoplasma genitalium metabolite
def: "Any bacterial metabolite produced during a metabolic reaction in <em>Mycoplasma genitalium</em>." []
is_a: CHEBI:76969 ! bacterial metabolite

[Term]
id: CHEBI:131605
name: dicarboxylic acid monoester(1-)
def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a dicarboxylic acid monoester." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:36244 ! is deprotonated form of dicarboxylic acid monoester

[Term]
id: CHEBI:131609
name: pneumocandin B0
def: "An echinocandin initially isolated as a very minor bioactive fermentation product of <em>Glarea lozoyensis</em> (originally known as <em>Zalerion arboricola</em>). Subsequent random mutagenesis work and optimisation of the fermentation medium permitted the industrial production of pneumocandin B<small><sub>0</sub></small>, which is used as the starting point for the synthesis of the antifungal drug caspofungin." []
is_a: CHEBI:24613 ! homodetic cyclic peptide
is_a: CHEBI:57248 ! echinocandin
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite

[Term]
id: CHEBI:131619
name: C27-steroid
def: "A steroid compound with a structure based on a 27-carbon (cholestane) skeleton." []
is_a: CHEBI:35341 ! steroid
relationship: RO:0018040 CHEBI:35516 ! has parent hydride cholestane

[Term]
id: CHEBI:131620
name: C24-steroid
def: "A steroid compound with a structure based on a 24-carbon (cholane) skeleton." []
is_a: CHEBI:131657 ! cholane derivative

[Term]
id: CHEBI:131621
name: C19-steroid
def: "A steroid compound with a structure based on a 19-carbon (androstane) skeleton." []
is_a: CHEBI:35341 ! steroid
relationship: RO:0018040 CHEBI:35509 ! has parent hydride androstane

[Term]
id: CHEBI:131657
name: cholane derivative
def: "Any steroid (or derivative) based on a cholane skeleton." []
is_a: CHEBI:35341 ! steroid
relationship: RO:0018040 CHEBI:35519 ! has parent hydride cholane

[Term]
id: CHEBI:131699
name: EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
def: "A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7)." []
is_a: CHEBI:38234 ! DNA polymerase inhibitor

[Term]
id: CHEBI:131701
name: poly(ethylene terephthalate)(1-)
def: "An ionic polymer resulting from the deprotonation of the terminal carboxy groups of poly(ethylene terephthalate) polymer." []
is_a: CHEBI:37997 ! homopolymer macromolecule
is_a: CHEBI:60164 ! ionic polymer
relationship: RO:0018033 CHEBI:61452 ! is deprotonated form of poly(ethylene terephthalate) polymer

[Term]
id: CHEBI:131770
name: EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
def: "A EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of channel-conductance-controlling ATPase (EC 3.6.3.49, also known as cystic fibrosis conductance regulator, CFCR)." []
is_a: CHEBI:76895 ! EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor

[Term]
id: CHEBI:131787
name: dopamine receptor D2 antagonist
def: "An antagonist that binds to and deactivates the dopamine receptor D<small><sub>2</sub></small>, the main receptor for all antipsychotic drugs." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:131822
name: sulfamate
def: "An organosulfonate oxoanion obtained by deprotonation of the <em>N</em>-sulfo group of any sulfamic acid; major species at pH 7.3." []
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:35719 ! is deprotonated form of sulfamic acids

[Term]
id: CHEBI:131823
name: methylated primary amine(1+)
def: "An organic cation obtained by protonation of any methylated primary amine; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative

[Term]
id: CHEBI:131860
name: octadecanoid anion
def: "An unsaturated fatty acid anion obtained by the deprotonation of the carboxy group of any octadecanoid." []
is_a: CHEBI:2580 ! unsaturated fatty acid anion
is_a: CHEBI:57560 ! long-chain fatty acid anion
relationship: RO:0018033 CHEBI:36326 ! is deprotonated form of octadecanoid

[Term]
id: CHEBI:131862
name: HPODE(1-)
def: "An octadecanoid anion anion obtained by the deprotonation of the carboxy group of any hydroperoxyoctadecadienoic acid." []
is_a: CHEBI:131860 ! octadecanoid anion
is_a: CHEBI:134019 ! hydroperoxy polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:36329 ! is deprotonated form of HPODE

[Term]
id: CHEBI:131863
name: docosanoid
def: "Any oxygenated derivative of C<small><sub>22</sub></small> polyunsaturated fatty acids, such as docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA)." []
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:26208 ! polyunsaturated fatty acid
relationship: RO:0018034 CHEBI:131864 ! is protonated form of docosanoid anion

[Term]
id: CHEBI:131864
name: docosanoid anion
def: "A polyunsaturated fatty acid anion obtained by the deprotonation of the carboxy group of any docosanoid." []
is_a: CHEBI:57560 ! long-chain fatty acid anion
relationship: RO:0018033 CHEBI:131863 ! is deprotonated form of docosanoid

[Term]
id: CHEBI:131871
name: hydroxy polyunsaturated fatty acid anion
def: "Any polyunsaturated fatty acid anion carrying one or more hydroxy substituents." []
is_a: CHEBI:59835 ! hydroxy fatty acid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:140345 ! is deprotonated form of hydroxy polyunsaturated fatty acid

[Term]
id: CHEBI:131878
name: cholanic acid anion
def: "Any steroid acid anion based on a cholanic acid skeleton." []
is_a: CHEBI:36235 ! bile acid anion

[Term]
id: CHEBI:131879
name: cholanic acid conjugate anion
def: "An organic anion obtained by deprotonation of any cholanic acid conjugate." []
is_a: CHEBI:25696 ! organic anion

[Term]
id: CHEBI:131899
name: (R)-imazamox(1-)
def: "A monocarboxylic acid anion resulting from the deprotonation of the carboxy group of (<i>R</i>)-imazamox." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:83744 ! is deprotonated form of (R)-imazamox
relationship: RO:0018039 CHEBI:133193 ! is enantiomer of (S)-imazamox(1-)

[Term]
id: CHEBI:131906
name: 4-pyranones
def: "A pyranone based on the structure of 4<em>H</em>-pyran-4-one and its substituted derivatives." []
is_a: CHEBI:37963 ! pyranone
is_a: CHEBI:3992 ! cyclic ketone

[Term]
id: CHEBI:131927
name: dicarboxylic acids and O-substituted derivatives
def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." []
is_a: CHEBI:36586 ! carbonyl compound

[Term]
id: CHEBI:131960
name: fluoroindole
def: "An organofluorine compound that is a compound based on an indole skeleton, containing one or more fluorine atoms." []
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:52507 ! haloindole

[Term]
id: CHEBI:132028
name: tauroursodeoxycholate
def: "An organosulfonate oxoanion that is the conjugate base of tauroursodeoxycholic acid arising from deprotonation of the sulfonate OH group; major species at pH 7.3." []
is_a: CHEBI:131879 ! cholanic acid conjugate anion
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:80774 ! is deprotonated form of tauroursodeoxycholic acid

[Term]
id: CHEBI:132053
name: thifensulfuron
def: "An <em>N</em>-sulfonylurea in which the sulfur atom is attached to a 2-carboxythiophen-3-yl group and in which the non-sulfonated nitrogen is substituted by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. The corresponding methyl ester, known as thifensulfuron-methyl, is used as a post-emergence herbicide for the control of grass and broad-leaved weeds." []
is_a: CHEBI:26588 ! 1,3,5-triazines
is_a: CHEBI:48436 ! thiophenecarboxylic acid
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:132082
name: entinostat
def: "A member of the class of benzamides resulting from the formal condensation of the carboxy group of the pyridin-3-ylmethyl carbamate derivative of <em>p</em>-(aminomethyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an inhibitor of histone deacetylase isoform 1 (HDAC1) and isoform 3 (HDAC3)." []
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0018038 CHEBI:34043 ! has functional parent 1,2-phenylenediamine

[Term]
id: CHEBI:132106
name: sodium propionate
def: "An organic sodium salt comprising equal numbers of sodium and propionate ions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: BFO:0000051 CHEBI:17272 ! has part propionate
relationship: RO:0000087 CHEBI:65255 ! has role food preservative
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:132124
name: 1,4-benzoquinones
def: "Any member of the class of benzoquinones that is 1,4-benzoquinone or its <em>C</em>-substituted derivatives." []
is_a: CHEBI:22729 ! benzoquinones
is_a: CHEBI:25830 ! p-quinones

[Term]
id: CHEBI:132130
name: hydroxyquinone
def: "Any quinone in which one or more of the carbons making up the quinone moiety is substituted by a hydroxy group." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:36141 ! quinone

[Term]
id: CHEBI:132142
name: 1,4-naphthoquinones
def: "A naphthoquinone in which the oxo groups of the quinone moiety are at positions 1 and 4 of the parent naphthalene ring." []
is_a: CHEBI:25481 ! naphthoquinone
is_a: CHEBI:25830 ! p-quinones

[Term]
id: CHEBI:132153
name: hyaluronate
def: "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." []
is_a: CHEBI:61469 ! polyanionic polymer
is_a: CHEBI:63551 ! carbohydrate acid derivative anion
relationship: RO:0018033 CHEBI:16336 ! is deprotonated form of hyaluronic acid

[Term]
id: CHEBI:132155
name: hydroxynaphthoquinone
def: "Any naphthoquinone in which the naphthaoquinone moiety is substituted by at least one hydroxy group." []
is_a: CHEBI:132130 ! hydroxyquinone
is_a: CHEBI:25481 ! naphthoquinone

[Term]
id: CHEBI:132157
name: hydroxy-1,4-naphthoquinone
def: "Any member of the class of 1,4-naphthoquinones in which the naphthoquinone moiety is substituted by at least one hydroxy group." []
is_a: CHEBI:132142 ! 1,4-naphthoquinones
is_a: CHEBI:132155 ! hydroxynaphthoquinone

[Term]
id: CHEBI:132181
name: diethylammonium
def: "A secondary aliphatic ammonium ion resulting from the protonation of the amino group of diethylamine." []
is_a: CHEBI:58855 ! secondary aliphatic ammonium ion
relationship: RO:0018034 CHEBI:85259 ! is protonated form of diethylamine

[Term]
id: CHEBI:132233
name: 1-phenylpropan-2-amine
def: "A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group." []
is_a: CHEBI:32877 ! primary amine

[Term]
id: CHEBI:132294
name: phenylephrine(1+)
def: "An organic cation obtained by protonation of the secondary amino function of phenylephrine." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:8093 ! is protonated form of phenylephrine

[Term]
id: CHEBI:132297
name: methamphetamine(1+)
def: "An organic cation obtained by protonation of the secondary amino function of methamphetamine." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:6809 ! is protonated form of methamphetamine

[Term]
id: CHEBI:132362
name: citrate(4-)
def: "A citrate anion obtained by deprotonation of the three carboxy groups as well as the hydroxy group of citric acid." []
is_a: CHEBI:133748 ! citrate anion
relationship: RO:0018033 CHEBI:16947 ! is deprotonated form of citrate(3-)

[Term]
id: CHEBI:132365
name: EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor
def: "An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of procollagen-proline dioxygenase (EC 1.14.11.2)." []
is_a: CHEBI:76902 ! EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor

[Term]
id: CHEBI:132446
name: perfluorobutanesulfonic acid
def: "A perfluoroalkanesulfonic acid that is butane-1-sulfonic acid in which all of the hydrogens of the butyl group have been replaced by fluorines." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132447 ! perfluoroalkanesulfonic acid
relationship: RO:0000087 CHEBI:35195 ! has role surfactant

[Term]
id: CHEBI:132447
name: perfluoroalkanesulfonic acid
def: "An organosulfonic acid in which the sulfo group is directly attached to a perfluoroalkyl group." []
is_a: CHEBI:134091 ! perfluorinated compound
is_a: CHEBI:33551 ! organosulfonic acid

[Term]
id: CHEBI:132448
name: perfluorohexanesulfonic acid
def: "A perfluoroalkanesulfonic acid that is hexane-1-sulfonic acid in which all thirteen of the hydrogens that are attached to carbons have been replaced by fluorines." []
is_a: CHEBI:132447 ! perfluoroalkanesulfonic acid

[Term]
id: CHEBI:13248
name: anilide
def: "Any aromatic amide obtained by acylation of aniline." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0018038 CHEBI:17296 ! has functional parent aniline

[Term]
id: CHEBI:132502
name: fatty acid 18:3
def: "Any trienoic fatty acid containing 18 carbons." []
is_a: CHEBI:73155 ! trienoic fatty acid

[Term]
id: CHEBI:132539
name: fatty acid 20:4
def: "Any polyunsaturated fatty acid containing 20 carbons and 4 double bonds." []
is_a: CHEBI:26208 ! polyunsaturated fatty acid

[Term]
id: CHEBI:132540
name: fatty acid 20:5
def: "Any polyunsaturated fatty acid containing 20 carbons and 5 double bonds." []
is_a: CHEBI:26208 ! polyunsaturated fatty acid

[Term]
id: CHEBI:132544
name: fatty acid 22:6
def: "Any polyunsaturated fatty acid containing 22 carbons and 6 double bonds." []
is_a: CHEBI:26208 ! polyunsaturated fatty acid

[Term]
id: CHEBI:132592
name: 1-methylcyclopropene
def: "A member of the class of cyclopropenes that is cyclopropene in which the hydrogen at position 1 has been replaced by a methyl group. A gas at room temperture and pressure, it is a (synthetic) ethylene perception inhibitor and is used to prolong the life of cut and potted flowers, other ornamental plants, and fruit." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33643 ! cycloalkene
is_a: CHEBI:51455 ! cyclopropenes
relationship: RO:0000087 CHEBI:26155 ! has role plant growth regulator
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:132717
name: bleaching agent
def: "A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties." []
is_a: CHEBI:33893 ! reagent

[Term]
id: CHEBI:132742
name: lysophosphatidic acid
def: "A member of the class of lysophosphatidic acids obtained by hydrolytic removal of one of the two acyl groups of any phosphatidic acid. A 'closed' class." []
is_a: CHEBI:32957 ! lysophosphatidic acids

[Term]
id: CHEBI:132744
name: lysophosphatidic acid 16:0
def: "A lysophosphatidic acid in which the acyl group (position not specified) contains 16 carbons and no double bonds." []
is_a: CHEBI:132742 ! lysophosphatidic acid

[Term]
id: CHEBI:132774
name: roxadustat
def: "An <em>N</em>-acylglycine resulting from the formal condensation of the amino group of glycine with the carboxy group of 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. It is an inhibitor of hypoxia inducible factor prolyl hydroxylase (HIF-PH)." []
is_a: CHEBI:16180 ! N-acylglycine
is_a: CHEBI:24922 ! isoquinolines
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:102248 ! has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
relationship: RO:0000087 CHEBI:132365 ! has role EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:132842
name: sulfapyridine
def: "A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:87228 ! sulfonamide antibiotic
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:45373 ! has functional parent sulfanilamide

[Term]
id: CHEBI:132889
name: graphene oxide
def: "A single carbon layer of the graphite oxide structure." []
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0018038 CHEBI:36973 ! has functional parent graphene

[Term]
id: CHEBI:132915
name: (R,S,S,S)-nebivolol(1+)
def: "An organic cation obtained by protonation of the secondary amino function of (<i>R</i>,<i>S</i>,<i>S</i>,<i>S</i>)-nebivolol." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:64020 ! is protonated form of (R,S,S,S)-nebivolol
relationship: RO:0018039 CHEBI:132916 ! is enantiomer of (S,R,R,R)-nebivolol(1+)

[Term]
id: CHEBI:132916
name: (S,R,R,R)-nebivolol(1+)
def: "An organic cation obtained by protonation of the secondary amino function of (<i>S</i>,<i>R</i>,<i>R</i>,<i>R</i>)-nebivolol." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:64021 ! is protonated form of (S,R,R,R)-nebivolol
relationship: RO:0018039 CHEBI:132915 ! is enantiomer of (R,S,S,S)-nebivolol(1+)

[Term]
id: CHEBI:132918
name: 1-methyl-4-imidazoleacetate
def: "A monocarboxylic acid anion that is the conjugate base of 1-methyl-4-imidazoleacetic acid, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:1606 ! is deprotonated form of 1-methyl-4-imidazoleacetic acid

[Term]
id: CHEBI:132922
name: ibuprofen(1-)
def: "A monocarboxylic acid anion that is the conjugate base of ibuprofen, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:5855 ! is deprotonated form of ibuprofen

[Term]
id: CHEBI:132932
name: disodium 5'-guanylate
def: "An organic sodium salt that is the disodium salt of GMP." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:58115 ! has part guanosine 5'-monophosphate(2-)
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent

[Term]
id: CHEBI:132941
name: 2-hydroxyglutarate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:17084 ! is deprotonated form of 2-hydroxyglutaric acid

[Term]
id: CHEBI:132943
name: aspartate
is_a: CHEBI:33558 ! alpha-amino-acid anion
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:22660 ! is deprotonated form of aspartic acid

[Term]
id: CHEBI:132944
name: octadec-9-enoate
def: "An octadecenoate in which the double bond is at C-9." []
is_a: CHEBI:78049 ! octadecenoate
relationship: RO:0018033 CHEBI:36021 ! is deprotonated form of octadec-9-enoic acid

[Term]
id: CHEBI:132950
name: tartrate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of any tartaric acid." []
is_a: CHEBI:33798 ! tetraric acid anion

[Term]
id: CHEBI:132951
name: maleate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of maleic acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:18300 ! is deprotonated form of maleic acid

[Term]
id: CHEBI:132952
name: oxalate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of oxalic acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:16995 ! is deprotonated form of oxalic acid

[Term]
id: CHEBI:132953
name: suberate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of suberic acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:9300 ! is deprotonated form of suberic acid

[Term]
id: CHEBI:132963
name: butyl 2-(4-\{[5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoate
def: "A carboxylic ester resulting from the formal condensation of the carboxy group 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid with the hydroxy group of butan-1-ol." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0018038 CHEBI:28885 ! has functional parent butan-1-ol
relationship: RO:0018038 CHEBI:83598 ! has functional parent 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid

[Term]
id: CHEBI:132964
name: fluazifop-P-butyl
def: "A butyl 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate that has <i>R</i> configutation. The active enantiomer of the herbicide fluazifop-butyl, it is used as a post-emergence herbicide for the control grass weeds in various broad-leaved crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132963 ! butyl 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
relationship: RO:0018038 CHEBI:83599 ! has functional parent fluazifop-P
relationship: RO:0018039 CHEBI:132965 ! is enantiomer of (S)-fluazifop-butyl

[Term]
id: CHEBI:132965
name: (S)-fluazifop-butyl
def: "A butyl 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate that has <i>S</i> configuration. It is the inactive enantiomer of the herbicide fluazifop-P-butyl." []
is_a: CHEBI:132963 ! butyl 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate
relationship: RO:0018039 CHEBI:132964 ! is enantiomer of fluazifop-P-butyl

[Term]
id: CHEBI:132970
name: 5-ammoniolevulinic acid
def: "A primary ammonium ion obtained by protonation of the amino group of 5-aminolevulinic acid." []
is_a: CHEBI:65296 ! primary ammonium ion
relationship: RO:0018034 CHEBI:17549 ! is protonated form of 5-aminolevulinic acid

[Term]
id: CHEBI:132972
name: farnesoid X receptor agonist
def: "An agonist that binds to and activates farnesoid X receptors" []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:132992
name: radiosensitizing agent
def: "A drug that makes increases the sensitivity of tumour cells to radiation therapy." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:133022
name: B-cell lymphoma 2 inhibitor
def: "Any inhibitor of B-cell lymphoma 2 protein." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:133135
name: chromenochromene
def: "Any organic heteroolycyclic compound whose skeleton two <em>ortho</em>-fused chromene rings, and their derivatives." []
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:133193
name: (S)-imazamox(1-)
def: "A monocarboxylic acid anion resulting from the deprotonation of the carboxy group of (<i>S</i>)-imazamox." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:83743 ! is deprotonated form of (S)-imazamox
relationship: RO:0018039 CHEBI:131899 ! is enantiomer of (R)-imazamox(1-)

[Term]
id: CHEBI:133210
name: 9-(beta-D-glucosyl)-trans-zeatin
def: "An <em>N</em>-glycosylzeatin that is <i>trans</i>-zeatin having a β-<small>D</small>-glucopyranosyl residue attached at position N-9." []
is_a: CHEBI:24289 ! glucosyl-N(6)-isopentenyladenine
is_a: CHEBI:38645 ! N-glycosylzeatin
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:133249
name: saturated fatty aldehyde
def: "A fatty aldehyde in which there is no carbon-carbon unsaturation." []
is_a: CHEBI:35746 ! fatty aldehyde
relationship: RO:0018038 CHEBI:26607 ! has functional parent saturated fatty acid

[Term]
id: CHEBI:133291
name: saturated dicarboxylic acid dianion(2-)
def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid that contains no carbon-carbon double bonds." []
is_a: CHEBI:28965 ! dicarboxylic acid dianion

[Term]
id: CHEBI:133305
name: sulfoxaflor
def: "A mixture of the four diastereoisomers arising from the two tetrahedral stereocentres of [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-λ<small><sup>6</small></sup>-sulfanylidene]cyanamide (the sulfur atom and the carbon attached to position 3 of the pyridine ring). [Both <i>E</i>- and <i>Z</i>-isomers involving the S=N double bond and the cyano group exist, but they interconvert rapidly at r.t.]. A nicotinic acetylcholine receptor agonist in insects, sulfoxaflor is used as an insecticide, particularly for the control of aphids." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60915 ! diastereoisomeric mixture
relationship: BFO:0000051 CHEBI:133311 ! has part (RC,RS)-sulfoxaflor
relationship: BFO:0000051 CHEBI:133312 ! has part (RC,SS)-sulfoxaflor
relationship: BFO:0000051 CHEBI:133313 ! has part (SC,SS)-sulfoxaflor
relationship: BFO:0000051 CHEBI:133315 ! has part (SC,RS)-sulfoxaflor
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:47958 ! has role nicotinic acetylcholine receptor agonist

[Term]
id: CHEBI:133306
name: [methyl(oxido)\{1-[6-(trifluoromethyl)pyridin-3-yl]ethyl\}-lambda(6)-sulfanylidene]cyanamide
def: "A member of the class of pyridines that is 5-ethyl-2-trifluoromethylpyridine in which the ethyl group is substituted at position 1 by an <em>N</em>-cyano-<em>S</em>-methylsulfonimidoyl group. The insecticide sulfoxalor is a mixture of the four possible stereoisomers arising from the two tetrahedral stereocentres." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38084 ! sulfoximide

[Term]
id: CHEBI:133311
name: (RC,RS)-sulfoxaflor
def: "A [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-λ<small><sup>6</small></sup>-sulfanylidene]cyanamide that has <i>R</i> configuration at both the sulfur atom and at the carbon attached to position 3 of the pyridine ring." []
is_a: CHEBI:133306 ! [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide
relationship: RO:0018039 CHEBI:133313 ! is enantiomer of (SC,SS)-sulfoxaflor

[Term]
id: CHEBI:133312
name: (RC,SS)-sulfoxaflor
def: "A [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-λ<small><sup>6</small></sup>-sulfanylidene]cyanamide that has <i>S</i> configuration at the sulfur atom and <i>R</i> configuration at the carbon attached to position 3 of the pyridine ring." []
is_a: CHEBI:133306 ! [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide
relationship: RO:0018039 CHEBI:133315 ! is enantiomer of (SC,RS)-sulfoxaflor

[Term]
id: CHEBI:133313
name: (SC,SS)-sulfoxaflor
def: "A [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-λ<small><sup>6</small></sup>-sulfanylidene]cyanamide that has <i>S</i> configuration at both the sulfur atom and at the carbon attached to position 3 of the pyridine ring." []
is_a: CHEBI:133306 ! [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide
relationship: RO:0018039 CHEBI:133311 ! is enantiomer of (RC,RS)-sulfoxaflor

[Term]
id: CHEBI:133315
name: (SC,RS)-sulfoxaflor
def: "A [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-λ<small><sup>6</small></sup>-sulfanylidene]cyanamide that has <i>R</i> configuration at the sulfur atom and <i>S</i> configuration at the carbon attached to position 3 of the pyridine ring." []
is_a: CHEBI:133306 ! [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide
relationship: RO:0018039 CHEBI:133312 ! is enantiomer of (RC,SS)-sulfoxaflor

[Term]
id: CHEBI:133331
name: metal oxide
def: "An inorganic oxide that is an oxide of any metal." []
is_a: CHEBI:24836 ! inorganic oxide

[Term]
id: CHEBI:133538
name: L-lysine zwitterion
def: "An <small>L</small>-α-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of <small>L</small>-lysine; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:59869 ! L-alpha-amino acid zwitterion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32551 ! is deprotonated form of L-lysinium(1+)
relationship: RO:0018034 CHEBI:32550 ! is protonated form of L-lysinate
relationship: RO:0018036 CHEBI:133538 ! is tautomer of L-lysine zwitterion
relationship: RO:0018036 CHEBI:18019 ! is tautomer of L-lysine

[Term]
id: CHEBI:133661
name: hyocholate
def: "A bile acid anion that is the conjugate base of hyocholic acid, obtained bye deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36235 ! bile acid anion
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0000087 CHEBI:86264 ! has role rat metabolite
relationship: RO:0018033 CHEBI:81244 ! is deprotonated form of hyocholic acid

[Term]
id: CHEBI:133670
name: p-cresol sulfate(1-)
def: "A phenyl sulfate oxoanion that is the conjugate base of <em>p</em>-cresol sulfate, obtained by deprotonation of the sulfate group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140317 ! phenyl sulfate oxoanion
relationship: RO:0000087 CHEBI:64584 ! has role uremic toxin
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:82933 ! has role gut flora metabolite
relationship: RO:0018033 CHEBI:82914 ! is deprotonated form of p-cresol sulfate

[Term]
id: CHEBI:133673
name: glyphosate(1-)
def: "An organophosphate oxoanion obtained by the deprotonation of the carboxy and one of the phosphate OH groups as well as protonation of the amino group of glyphosate. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:27744 ! is deprotonated form of glyphosate
relationship: RO:0018034 CHEBI:67052 ! is protonated form of glyphosate(2-)

[Term]
id: CHEBI:133737
name: acetyltaurine(1-)
def: "An organosulfonate oxoanion obtained by deprotonation of the sulfonic acid group of acetyltaurine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134249 ! alkanesulfonate oxoanion
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018033 CHEBI:84415 ! is deprotonated form of acetyltaurine

[Term]
id: CHEBI:133744
name: homovanillate
def: "A  hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:545959 ! is deprotonated form of homovanillic acid

[Term]
id: CHEBI:133748
name: citrate anion
def: "A tricarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of citric acid." []
is_a: CHEBI:35753 ! tricarboxylic acid anion
relationship: RO:0018033 CHEBI:30769 ! is deprotonated form of citric acid

[Term]
id: CHEBI:133790
name: linolenate
def: "A polyunsaturated fatty acid anion obtained by deprotonation of the carboxy group of either α- or γ-linolenic acid." []
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:59203 ! straight-chain fatty acid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:25048 ! is deprotonated form of linolenic acid

[Term]
id: CHEBI:133833
name: benznidazole
def: "A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitroimidazol-1-yl)acetic acid with the aromatic amino group of benzylamine. Used for treatment of Chagas disease." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35716 ! C-nitro compound
relationship: RO:0000087 CHEBI:36335 ! has role trypanocidal drug
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent

[Term]
id: CHEBI:133917
name: ochratoxin alpha
def: "A member of the class of isocoumarins that is 1-oxo-3,4-dihydro-2-benzopyran-7-carboxylic acid carrying additional methyl, chloro and hydroxy substituents at positions 3, 5 and 8 respectively. A non-toxic metabolite of the mycotoxin ochratoxin A." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38758 ! isocoumarins
is_a: CHEBI:38762 ! isochromanes
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0000087 CHEBI:83399 ! has role marine xenobiotic metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018034 CHEBI:192527 ! is protonated form of ochratoxin alpha(1-)

[Term]
id: CHEBI:133959
name: 4'-methoxyisoflavones
def: "Any methoxyisoflavone which has a methoxy group at the 4-position of the phenyl substituent." []
is_a: CHEBI:38756 ! methoxyisoflavone

[Term]
id: CHEBI:133972
name: primary nitroalkane
def: "A nitroalkane in which the nitro group is attached to a terminal carbon. Major microspecies at pH 7.3." []
is_a: CHEBI:7587 ! nitroalkane

[Term]
id: CHEBI:134019
name: hydroperoxy polyunsaturated fatty acid anion
def: "Any polyunsaturated fatty acid anion carrying one or more hydroperoxy substituents." []
is_a: CHEBI:64012 ! hydroperoxy fatty acid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:189832 ! is deprotonated form of hydroperoxy polyunsaturated fatty acid

[Term]
id: CHEBI:134024
name: chlorofluorocarbon
def: "An organochlorine compound derived from methane, ethane or propane that contains atoms of carbon, chlorine, and fluorine only. They are nontoxic, nonflammable chemicals used in aerosol sprays and as refrigerants. Being ozone depletion agents, their manufacture and use is being phased out under the Montreal Protocol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:134040
name: hydrochlorofluorocarbon
def: "An organochlorine compound derived from methane, ethane or propane that contains atoms of hydrogen, chlorine, fluorine, and carbon only." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:134043
name: phenylureas
def: "Any member of the class of ureas in which at least one of the nitrogens of the urea moiety is substituted by a phenyl or substituted phenyl group." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:47857 ! ureas

[Term]
id: CHEBI:134044
name: 1,4-dioxine
def: "An oxacycle that is 4<em>H</em>-pyran in which the methylene group at position 4 is replaced by an oxygen. Non-aromatic." []
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:134045
name: polychlorinated dibenzodioxines and related compounds
def: "Organochlorine compounds that are polychlorinated dibenzodioxines and structurally related entities that are persistant organic pollutants. These include polychlorinated dibenzofurans as well as polychlorinated and polybrominated biphenyls  They vary widely in their toxicity, but their toxic mode of action is through the aryl hydrocarbon receptor." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17792 ! organohalogen compound
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:134046
name: polychlorinated dibenzofuran
def: "A member of the class of benzofurans that is benzofuran in which two or more of the hydrogens have reen replaced by chlorines." []
is_a: CHEBI:134045 ! polychlorinated dibenzodioxines and related compounds
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38922 ! dibenzofurans
relationship: RO:0000087 CHEBI:138015 ! has role endocrine disruptor

[Term]
id: CHEBI:134047
name: bromobiphenyl
def: "A bromoarene that consists of a biphenyl skeleton substituted by one or more bromo groups." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:37148 ! bromoarene
is_a: CHEBI:37149 ! bromobenzenes

[Term]
id: CHEBI:134049
name: polybromobiphenyl
def: "A biphenyl compound containing between 2 and 10 bromine atoms attached to the two benzene rings." []
is_a: CHEBI:134045 ! polychlorinated dibenzodioxines and related compounds
is_a: CHEBI:134047 ! bromobiphenyl

[Term]
id: CHEBI:134050
name: 2,2',4,4',5,5'-hexabromobiphenyl
def: "A polybromobiphenyl that is biphenyl in which the hydrogens at positions 2, 2', 4, 4', 5, and 5' have been replace by bromines." []
is_a: CHEBI:134049 ! polybromobiphenyl
is_a: CHEBI:172368 ! brominated flame retardant

[Term]
id: CHEBI:134063
name: 1,2,5,6,9,10-hexabromocyclododecane
def: "A bromoalkane consisting of cyclododecane bearing six bromo substituents at positions 1, 2, 5, 6, 9 and 10." []
is_a: CHEBI:172368 ! brominated flame retardant
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:22929 ! bromoalkane
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:134069
name: copper oxide
def: "Any metal oxide in which the metallic component is copper." []
is_a: CHEBI:133331 ! metal oxide
is_a: CHEBI:23377 ! copper molecular entity

[Term]
id: CHEBI:134091
name: perfluorinated compound
def: "An organofluorine compound containing only C-F bonds (no C-H bonds) and C-C bonds but also other heteroatoms (particularly other halogens, oxygen, and sulfur). Their properties represent a blend of fluorocarbons (containing only C-F and C-C bonds) and the parent functionalised organic species." []
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:134092
name: arsenocholine
def: "An arsonium ion that is choline in which the central nitrogen has been replaced by arsenic." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33406 ! organoarsenic compound
is_a: CHEBI:62607 ! arsonium ion
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite

[Term]
id: CHEBI:134094
name: polybromodiphenyl ether
def: "An aromatic ether that is diphenyl ether carrying between 2 and 10 bromo substituents attached to the two benzene rings." []
is_a: CHEBI:172368 ! brominated flame retardant
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37149 ! bromobenzenes
relationship: RO:0000087 CHEBI:138015 ! has role endocrine disruptor
relationship: RO:0018038 CHEBI:39258 ! has functional parent diphenyl ether

[Term]
id: CHEBI:134107
name: CHIR-090
def: "An <small>L</small>-threonine derivative obtained by formal condensation of the carboxy group of 4-({4-[(morpholin-4-yl)methyl]phenyl}ethynyl)benzoic acid with the amino group of <em>N</em>-hydroxy-<small>L</small>-threoninamide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:24650 ! hydroxamic acid
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:73474 ! acetylenic compound
is_a: CHEBI:84189 ! L-threonine derivative
relationship: RO:0000087 CHEBI:134108 ! has role lipopolysaccharide biosynthesis inhibitor
relationship: RO:0000087 CHEBI:134109 ! has role EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:134108
name: lipopolysaccharide biosynthesis inhibitor
def: "Any compound that inhibits the biosynthesis of any lipopolysaccharide." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:134109
name: EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor
def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of UDP-3-<em>O</em>-acyl-<em>N</em>-acetylglucosamine deacetylase (EC 3.5.1.108)." []
is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor

[Term]
id: CHEBI:134179
name: volatile organic compound
def: "Any organic compound having an initial boiling point less than or equal to 250 °C (482 °F) measured at a standard atmospheric pressure of 101.3 kPa." []
is_a: CHEBI:72695 ! organic molecule

[Term]
id: CHEBI:134209
name: aporphine alkaloid
def: "Any benzylisoquinoline alkaloid that has a structure based on 4<em>H</em>-dibenzo[<em>de,g</em>]quinoline or its 3-methyl derivative." []
is_a: CHEBI:22750 ! benzylisoquinoline alkaloid

[Term]
id: CHEBI:134216
name: muricholic acids
def: "A group of trihydroxy-5β-cholanic acids that are the 6,7-diastereoisomers of 3α,6,7-trihydroxy-5β-cholan-24-oic acid." []
is_a: CHEBI:131620 ! C24-steroid
is_a: CHEBI:27114 ! trihydroxy-5beta-cholanic acid
is_a: CHEBI:3098 ! bile acid
is_a: CHEBI:36835 ! 3alpha-hydroxy steroid
is_a: CHEBI:36844 ! 7-hydroxy steroid
is_a: CHEBI:36849 ! 6-hydroxy steroid

[Term]
id: CHEBI:134249
name: alkanesulfonate oxoanion
def: "An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups." []
is_a: CHEBI:33554 ! organosulfonate oxoanion

[Term]
id: CHEBI:134251
name: guaiacols
def: "Any phenol carrying an additional methoxy substituent at the <em>ortho</em>-position." []
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:134361
name: allylic alcohol
def: "An alcohol where the hydroxy group is attached to a saturated carbon atom adjacent to a double bond (R groups may be H, organyl, etc.)." []
is_a: CHEBI:30879 ! alcohol
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:134362
name: homoallylic alcohol
def: "An aliphatic alcohol where the hydroxy carbon is β to a double bond." []
is_a: CHEBI:2571 ! aliphatic alcohol
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:134363
name: tertiary amine oxide
def: "An <em>N</em>-oxide where there are three organic groups bonded to the nitrogen atom." []
is_a: CHEBI:35580 ! N-oxide
relationship: RO:0018038 CHEBI:50996 ! has functional parent tertiary amino compound

[Term]
id: CHEBI:134394
name: primary allylic alcohol
def: "An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to two hydrogens." []
is_a: CHEBI:134361 ! allylic alcohol
is_a: CHEBI:15734 ! primary alcohol

[Term]
id: CHEBI:134396
name: secondary allylic alcohol
def: "An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to one other carbon and one hydrogen." []
is_a: CHEBI:134361 ! allylic alcohol
is_a: CHEBI:35681 ! secondary alcohol

[Term]
id: CHEBI:134397
name: tertiary allylic alcohol
def: "An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to two other carbons (R4,R5 ≠ H)." []
is_a: CHEBI:134361 ! allylic alcohol
is_a: CHEBI:26878 ! tertiary alcohol

[Term]
id: CHEBI:134403
name: poly(styrene) nanoparticle
def: "A nanoparticle composed of poly(styrene)." []
is_a: CHEBI:50803 ! nanoparticle
is_a: CHEBI:53276 ! poly(styrene)

[Term]
id: CHEBI:134438
name: titanium oxides
def: "A class containing any titanium molecular entity that is an oxide of titanium." []
is_a: CHEBI:37217 ! titanium molecular entity

[Term]
id: CHEBI:134441
name: titanium oxide nanoparticle
def: "A nanoparticle composed of any titanium oxide." []
is_a: CHEBI:134438 ! titanium oxides
is_a: CHEBI:52855 ! inorganic nanoparticle

[Term]
id: CHEBI:134504
name: tenofovir(1-)
def: "A phosphorus oxoanion resulting from the removal of one proton from the phosphonic acid group of tenofovir. The major microspecies at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33461 ! phosphorus oxoanion
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor
relationship: RO:0018033 CHEBI:63625 ! is deprotonated form of tenofovir (anhydrous)

[Term]
id: CHEBI:134688
name: naltrexone(1+)
def: "An organic cation that is conjugate acid of naltrexone resulting from the protonation of the amino group; Major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:7465 ! is protonated form of naltrexone

[Term]
id: CHEBI:134751
name: avobenzone
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:71230 ! dihydrochalcones
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:134990
name: agomelatine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:25477 ! naphthalenes
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent

[Term]
id: CHEBI:135005
name: milnacipran
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug

[Term]
id: CHEBI:135526
name: octocrylene
is_a: CHEBI:51614 ! diarylmethane
is_a: CHEBI:60911 ! racemate

[Term]
id: CHEBI:135752
name: tafenoquine
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-tafenoquine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:141488 ! has part (R)-tafenoquine
relationship: BFO:0000051 CHEBI:141489 ! has part (S)-tafenoquine
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:36335 ! has role trypanocidal drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent

[Term]
id: CHEBI:135777
name: (S)-nicardipine
def: "The <i>S</i>-enantiomer of nicardipine." []
is_a: CHEBI:180905 ! 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0018039 CHEBI:180904 ! is enantiomer of (R)-nicardipine

[Term]
id: CHEBI:135918
name: chidamide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:135983
name: teriparatide
is_a: CHEBI:15841 ! polypeptide

[Term]
id: CHEBI:136002
name: krypton (81mKr) gas
is_a: CHEBI:33583 ! noble gas molecular entity
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:136003
name: levomethadone
def: "A 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (<i>R</i>)-configuration. It is the active enantiomer of methadone and its hydrochloride salt is used to treat adults who are addicted to drugs such as heroin and morphine." []
is_a: CHEBI:167309 ! 6-(dimethylamino)-4,4-diphenylheptan-3-one
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0018039 CHEBI:167308 ! is enantiomer of dextromethadone

[Term]
id: CHEBI:13601
name: 3-oxo-5alpha-steroid
def: "A 3-oxo steroid that has α configuration at position 5." []
is_a: CHEBI:47788 ! 3-oxo steroid

[Term]
id: CHEBI:136054
name: arterolane
def: "An oxaspiro compound that is dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.1<small><sup>3,7</small></sup>]decane] substituted by a 2-[(2-amino-2-methylpropyl)amino]-2-oxoethyl group at position 4<i>s</i>. Its maleic acid salt is used as an antimalarial drug in combination with piperaquine." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:155930 ! trioxolane
is_a: CHEBI:37948 ! oxaspiro compound
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:51339 ! adamantanes
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0018033 CHEBI:155928 ! is deprotonated form of arterolane(1+)

[Term]
id: CHEBI:136184
name: jasmonic acid anion
def: "A 5-oxo monocarboxylic acid anion obtained by deprotonation of the carboxy group of any diastereomer of jasmonic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35975 ! 5-oxo monocarboxylic acid anion
relationship: RO:0000087 CHEBI:24937 ! has role jasmonates

[Term]
id: CHEBI:136185
name: VX nerve agent
def: "A organic thiophosphate that is the ethyl ester of <i>S</i>-{2-[di(propan-2-yl)amino]ethyl} <em>O</em> hydrogen methylphosphonothioate. A toxic nerve agent used in chemical warfare." []
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:136428
name: N-hydroxyimidothioate
def: "An imidothioate in which the nitrogen is substituted by a hydroxy group." []
is_a: CHEBI:83991 ! imidothioate

[Term]
id: CHEBI:13643
name: glycol
def: "A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent." []
is_a: CHEBI:23824 ! diol

[Term]
id: CHEBI:136438
name: D-thioglucoside
def: "A thioglucoside in which the thioglucosyl moiety has <small>D</small> configuration." []
is_a: CHEBI:9553 ! thioglucoside

[Term]
id: CHEBI:136440
name: beta-D-thioglucoside
def: "A <small>D</small>-thioglucoside that has β configuration at position 1." []
is_a: CHEBI:136438 ! D-thioglucoside
relationship: RO:0018038 CHEBI:42896 ! has functional parent 1-thio-beta-D-glucopyranose

[Term]
id: CHEBI:136442
name: desulfoglucosinolic acid
def: "A β-<small>D</small>-thioglucoside formed by the formal condensation of the thiol group of an <em>N</em>-hydroxyimidothioate with β-<small>D</small>-glucose." []
is_a: CHEBI:136428 ! N-hydroxyimidothioate
is_a: CHEBI:136440 ! beta-D-thioglucoside

[Term]
id: CHEBI:136528
name: dihydroxydocosahexaenoate
def: "A hydroxy polyunsaturated fatty acid anion obtained by the deprotonation of the carboxy group of any dihydroxydocosahexaenoic acid." []
is_a: CHEBI:131864 ! docosanoid anion
is_a: CHEBI:131871 ! hydroxy polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:137348 ! is deprotonated form of dihydroxydocosahexaenoic acid

[Term]
id: CHEBI:136622
name: aci-nitro compound
def: "Organonitrogen compounds that have the general structure R<small><sup>1</small></sup>(R<small><sup>2</small></sup>)C=N(O)OH (R<small><sup>1</small></sup>,R<small><sup>2</small></sup> = H, organyl). They are tautomers of <em>C</em>-nitro compounds." []
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0018036 CHEBI:35716 ! is tautomer of C-nitro compound
relationship: RO:0018038 CHEBI:25750 ! has functional parent oxime

[Term]
id: CHEBI:136643
name: propesticide
def: "A prodrug that, on administration, undergoes chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active pesticide for which it is a propesticide." []
is_a: CHEBI:136859 ! pro-agent
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:136644
name: proinsecticide
def: "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proinsecticide." []
is_a: CHEBI:136643 ! propesticide
is_a: CHEBI:24852 ! insecticide

[Term]
id: CHEBI:136645
name: profungicide
def: "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active fungicide for which it is a profungicide." []
is_a: CHEBI:136643 ! propesticide
is_a: CHEBI:24127 ! fungicide

[Term]
id: CHEBI:136646
name: proherbicide
def: "A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide for which it is a proherbicide." []
is_a: CHEBI:136643 ! propesticide
is_a: CHEBI:24527 ! herbicide

[Term]
id: CHEBI:136684
name: pyrazolooxadiazepine
def: "An organic heterobicyclic compound whose skeleton consists of a pyrazole ring ortho-fused to a diazepine ring." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:1367
name: 3,3',4,4'-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl that is biphenyl in which the hydrogens at position 3 and 4 on each phenyl group are replaced by chlorines." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl

[Term]
id: CHEBI:136702
name: ximelagatran (hydroxylamine form)
def: "A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted into the corresponding ethyl ester and in which the amidine group has been converted to the corresponding hydroxylamine. Tautomeric with the oxime form of ximelagatran." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:24709 ! hydroxylamines
is_a: CHEBI:38777 ! azetidines
relationship: RO:0018036 CHEBI:65172 ! is tautomer of ximelagatran

[Term]
id: CHEBI:136849
name: 3-oxo-Delta(4)-steroid group
def: "An organic group derived from any 3-oxo-Δ<small><sup>4</small></sup>-steroid." []
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:136859
name: pro-agent
def: "A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:136889
name: 5beta steroid
def: "Any steroid that has β-configuration at position 5." []
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:136962
name: peptidylamide(1+)
def: "A peptide cation obtained by protonation of the amino terminus of any peptidylamide; major species at pH 7.3." []
is_a: CHEBI:60194 ! peptide cation
relationship: RO:0018034 CHEBI:15722 ! is protonated form of peptidyl amide

[Term]
id: CHEBI:13719
name: acetylsalicylate
def: "A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group." []
is_a: CHEBI:22718 ! benzoates
relationship: RO:0018033 CHEBI:15365 ! is deprotonated form of acetylsalicylic acid
relationship: RO:0018038 CHEBI:30762 ! has functional parent salicylate

[Term]
id: CHEBI:137348
name: dihydroxydocosahexaenoic acid
def: "A docosanoid that consists of any docosahexaenoic acid carrying two hydroxy substituents at unspecified positions." []
is_a: CHEBI:131863 ! docosanoid
is_a: CHEBI:140345 ! hydroxy polyunsaturated fatty acid
is_a: CHEBI:35972 ! dihydroxy monocarboxylic acid
relationship: RO:0018034 CHEBI:136528 ! is protonated form of dihydroxydocosahexaenoate

[Term]
id: CHEBI:137419
name: secondary ammonium ion
def: "An organic cation obtained by protonation of any secondary amino compound; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:32863 ! is protonated form of secondary amine

[Term]
id: CHEBI:137504
name: quinoxaline herbicide
def: "A quinoxaline pesticide that has herbicidal activity." []
is_a: CHEBI:38821 ! quinoxaline pesticide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide

[Term]
id: CHEBI:137507
name: quizalofop-P
def: "A 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid that has <i>R</i> configuration. An acetyl-CoA carboxylase inhibitor, it is used (generally as the corresponding ethyl or tefuryl ester proherbicides) for the control of annual and perennial grass weeds in sugar beet." []
is_a: CHEBI:137504 ! quinoxaline herbicide
is_a: CHEBI:137509 ! 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
relationship: RO:0018039 CHEBI:137513 ! is enantiomer of (S)-quizalofop

[Term]
id: CHEBI:137509
name: 2-\{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy\}propanoic acid
def: "A monocarboxylic acid that is 2-phenoxypropanoic acid in which the phenyl group is substituted at the <em>para</em> position by a (6-chloroquinoxalin-2-yl)oxy group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38771 ! quinoxaline derivative

[Term]
id: CHEBI:137513
name: (S)-quizalofop
def: "A 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid that has <i>S</i> configuration. It is the (inactive) enantiomer of the herbicide quizalofop-P." []
is_a: CHEBI:137509 ! 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid
relationship: RO:0018039 CHEBI:137507 ! is enantiomer of quizalofop-P

[Term]
id: CHEBI:137626
name: EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of 11β-hydroxysteroid dehydrogenase (EC 1.1.1.146)." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:137937
name: ethyl 2-\{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy\}propanoate
def: "An ethyl ester resulting from the formal condensation of the carboxy group of 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid with ethanol." []
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38771 ! quinoxaline derivative
relationship: RO:0018038 CHEBI:137509 ! has functional parent 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid

[Term]
id: CHEBI:137938
name: quizalofop-P-ethyl
def: "An ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate that has <i>R</i> configuration. A proherbicide for quizalofop-P, it is used to control annual and perennial grass weeds in a variety of crops, including potatoes, sugar beet, peanuts, cotton and flax." []
is_a: CHEBI:137504 ! quinoxaline herbicide
is_a: CHEBI:137937 ! ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate
relationship: RO:0000087 CHEBI:136646 ! has role proherbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0018038 CHEBI:137507 ! has functional parent quizalofop-P
relationship: RO:0018039 CHEBI:137939 ! is enantiomer of (S)-quizalofop-ethyl

[Term]
id: CHEBI:137939
name: (S)-quizalofop-ethyl
def: "An ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate that has <i>S</i> configuration." []
is_a: CHEBI:137937 ! ethyl 2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate
relationship: RO:0018039 CHEBI:137938 ! is enantiomer of quizalofop-P-ethyl

[Term]
id: CHEBI:137978
name: 1,3-dichloropropane
def: "A chloroalkane that is propane in which a hydrogen from each of the terminal methyl groups has been replaced by a chlorine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23115 ! chlorohydrocarbon
is_a: CHEBI:23128 ! chloroalkane
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:137980
name: metalloid atom
def: "An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included." []
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:137982
name: tertiary ammonium ion
def: "An organic cation obtained by protonation of the amino group of any tertiary amino compound." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:50996 ! is protonated form of tertiary amino compound

[Term]
id: CHEBI:137983
name: methylated tertiary amine
def: "A quaternary ammonium ion obtained by methylation of any tertiary amine" []
is_a: CHEBI:35267 ! quaternary ammonium ion

[Term]
id: CHEBI:138000
name: 3-(1-methylpyrrolidin-2-yl)pyridine
def: "An <em>N</em>-alkylpyrrolidine that consists of <em>N</em>-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2." []
is_a: CHEBI:26416 ! pyridine alkaloid
is_a: CHEBI:26456 ! pyrrolidine alkaloid
is_a: CHEBI:46775 ! N-alkylpyrrolidine

[Term]
id: CHEBI:138001
name: 2-bromophenyl 2,4-dibromophenyl ether
def: "A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 2', and 4 positions have been replaced by bromines." []
is_a: CHEBI:134094 ! polybromodiphenyl ether

[Term]
id: CHEBI:138015
name: endocrine disruptor
def: "Any compound that can disrupt the functions of the endocrine (hormone) system" []
is_a: CHEBI:51061 ! hormone receptor modulator

[Term]
id: CHEBI:138036
name: 4-bromophenyl 2,4-dibromophenyl ether
def: "A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, and 4' positions have been replaced by bromines." []
is_a: CHEBI:134094 ! polybromodiphenyl ether

[Term]
id: CHEBI:138038
name: 2,4-dibromophenyl 3,4-dibromophenyl ether
def: "A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, 3', and 4' positions have been replaced by bromines." []
is_a: CHEBI:134094 ! polybromodiphenyl ether

[Term]
id: CHEBI:138064
name: 2,4-dibromophenyl 2,3,4-tribromophenyl ether
def: "A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 3, 4, 2', and 4' positions have been replaced by bromines." []
is_a: CHEBI:134094 ! polybromodiphenyl ether

[Term]
id: CHEBI:138065
name: 2,4-dibromophenyl 2,4,6-tribromophenyl ether
def: "A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, 6, 2', and 4' positions have been replaced by bromines." []
is_a: CHEBI:134094 ! polybromodiphenyl ether

[Term]
id: CHEBI:138089
name: perfluorooctanesulfonamide
def: "A perfluorinated compound that is perfluorooctane in which one of the terminal fluorines has been replace by a sulfamoyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134091 ! perfluorinated compound
is_a: CHEBI:35358 ! sulfonamide
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:138103
name: inorganic acid
def: "A Brønsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." []
is_a: CHEBI:39141 ! Bronsted acid

[Term]
id: CHEBI:138141
name: 17alpha-hydroxy-C21-steroid
def: "Any C<small><sub>21</sub></small>-steroid carrying a hydroxy substituent at the 17α-position. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure." []
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:61313 ! C21-steroid

[Term]
id: CHEBI:138163
name: fomesafen(1-)
def: "An organic nitrogen anion resulting from the removal of a proton from the <em>N</em>-sulfonylcarboxamide moiety of fomesafen." []
is_a: CHEBI:50335 ! organic nitrogen anion
relationship: RO:0018033 CHEBI:81925 ! is deprotonated form of fomesafen

[Term]
id: CHEBI:138208
name: carotenoid biosynthesis inhibitor
def: "Any pathway inhibitor that acts on the carotenoid biosynthesis pathway." []
is_a: CHEBI:76932 ! pathway inhibitor

[Term]
id: CHEBI:138238
name: pyrimidine ribonucleoside 5'-monophosphate(2-)
def: "A nucleoside 5'-monophosphate(2−) obtained by deprotonation of the phospohate OH groups of any pyrimidine ribonucleoside 5'-monophosphate; major species at pH 7.3." []
is_a: CHEBI:58043 ! nucleoside 5'-monophosphate(2-)

[Term]
id: CHEBI:138366
name: bile acids
def: "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5β-configuration, while in lower vertebrates, some bile acids, known as <i>allo</i>-bile acids, have 5α-configuration." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35350 ! hydroxy steroid
is_a: CHEBI:36078 ! cholanoid

[Term]
id: CHEBI:13850
name: apoprotein
def: "An apoprotein is a protein devoid of its characteristic prosthetic group or metal." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38560 ! simple protein
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:138518
name: dialkyl phosphate(1-)
def: "An organophosphate oxoanion obtained by deprotonation of the phosphate OH group of any dialkyl phosphate; major species at pH 7.3." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:16648 ! is deprotonated form of dialkyl phosphate

[Term]
id: CHEBI:138625
name: (+)-jasmonic acid anion
def: "A jasmonate anion resulting from the removal of a proton from the carboxy group of (+)-jasmonic acid; major species at pH 7.3." []
is_a: CHEBI:136184 ! jasmonic acid anion
relationship: RO:0018033 CHEBI:139300 ! is deprotonated form of (+)-jasmonic acid

[Term]
id: CHEBI:138655
name: protectin D1
def: "A dihydroxydocosahexaenoic acid that is (4<i>Z</i>,7<i>Z</i>,11<i>E</i>,13<i>E</i>,15<i>Z</i>,19<i>Z</i>)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10<i>R</i>,17<i>S</i>-stereoisomer). Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1" []
is_a: CHEBI:134396 ! secondary allylic alcohol
is_a: CHEBI:137348 ! dihydroxydocosahexaenoic acid
is_a: CHEBI:193572 ! protectin
relationship: RO:0000087 CHEBI:140399 ! has role specialised pro-resolving mediator
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:71554 ! has role PPARgamma agonist
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:195348 ! is protonated form of protectin D1(1-)

[Term]
id: CHEBI:138675
name: gas molecular entity
def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0°C and 100 kPa)." []
is_a: CHEBI:33579 ! main group molecular entity

[Term]
id: CHEBI:138880
name: autophagy inducer
def: "Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell)." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:139114
name: carotenoid psi-end derivative
def: "Any carotenoid derivative with a ψ-end group." []
is_a: CHEBI:23044 ! carotenoid

[Term]
id: CHEBI:139120
name: carotenoid beta-end derivative
def: "Any carotenoid derivative with an β-end group" []
is_a: CHEBI:23044 ! carotenoid

[Term]
id: CHEBI:139133
name: 6-ketolithocholic acid
is_a: CHEBI:3098 ! bile acid

[Term]
id: CHEBI:139218
name: secondary nitroalkane
def: "A nitroalkane in which the nitro group, -NO<small><sub>2</sub></small>, is attached to a saturated carbon atom which has two other carbon atoms attached to it. Major microspecies at pH 7.3." []
is_a: CHEBI:7587 ! nitroalkane

[Term]
id: CHEBI:139300
name: (+)-jasmonic acid
is_a: CHEBI:35871 ! oxo monocarboxylic acid
is_a: CHEBI:36140 ! cyclopentanones
relationship: RO:0000087 CHEBI:24937 ! has role jasmonates
relationship: RO:0018034 CHEBI:138625 ! is protonated form of (+)-jasmonic acid anion
relationship: RO:0018039 CHEBI:18292 ! is enantiomer of jasmonic acid

[Term]
id: CHEBI:139322
name: poly(ethylene glycol) derivative
def: "A polyether that is any poly(ethylene glycol) in which one or both of the terminal hydroxy groups has been substituted or undergone modification." []
is_a: CHEBI:46774 ! polyether
relationship: RO:0018038 CHEBI:46793 ! has functional parent poly(ethylene glycol)

[Term]
id: CHEBI:139340
name: 1,3-dihydroimidazole-2-thiones
def: "A member of the class of imidazoles that is 1,3-dihydroimidazole-2-thione and its derivatives by substitution." []
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:51276 ! thioureas

[Term]
id: CHEBI:139358
name: isotopically modified compound
def: "Any molecular entity in which the isotopic ratio of nuclides for at least one element deviates measurably from that occurring in nature. The term includes both <em>isotopically substituted</em> compounds (in which essentially all the molecules of the compound have only the indicated nuclide(s) at each designated position) and <em>isotopically labeled</em> compounds (a formal mixture of an isotopically unmodified compound with one or more analogous isotopically substituted compound(s)." []
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:139359
name: tritiated compound
def: "Any isotopically modified compound that has one or more hydrogens replaced by tritium." []
is_a: CHEBI:139358 ! isotopically modified compound

[Term]
id: CHEBI:139361
name: TRP channel blocker
def: "An agent that inhibits the passage of cations through the transient receptor potential (TRP) channels." []
is_a: CHEBI:142783 ! TRP channel modulator

[Term]
id: CHEBI:139371
name: aryl sulfate oxoanion
def: "An organosulfate oxoanion obtained by deprotonation of the sulfo group of any aryl sulfate. The R group in this structure represents an aromatic ring." []
is_a: CHEBI:58958 ! organosulfate oxoanion
relationship: RO:0018034 CHEBI:37919 ! is protonated form of aryl sulfate

[Term]
id: CHEBI:13941
name: carbamate
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:28616 ! is deprotonated form of carbamic acid

[Term]
id: CHEBI:139492
name: sensitiser
def: "A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:139512
name: EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor
def: "An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9." []
is_a: CHEBI:76857 ! EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:139520
name: phenolic donor
def: "Any phenol that acts as an electron donor." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:15022 ! has role electron donor

[Term]
id: CHEBI:139588
name: alpha-hydroxy ketone
def: "A ketone containing a hydroxy group on the α-carbon relative to the C=O group." []
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:139589
name: retinoid anion
def: "A carboxylic acid anion obtained by deprotonation of any retinoid carboxy group." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:26537 ! is deprotonated form of retinoid

[Term]
id: CHEBI:139590
name: primary alpha-hydroxy ketone
def: "An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH<small><sub>2</sub></small> (methylene) group." []
is_a: CHEBI:139588 ! alpha-hydroxy ketone
is_a: CHEBI:15734 ! primary alcohol

[Term]
id: CHEBI:139592
name: tertiary alpha-hydroxy ketone
def: "An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups." []
is_a: CHEBI:139588 ! alpha-hydroxy ketone
is_a: CHEBI:26878 ! tertiary alcohol

[Term]
id: CHEBI:140190
name: calcium-dependent antibiotics
def: "Any antimicrobial agent whose activity is dependent on the presence of calcium ions." []
is_a: CHEBI:33281 ! antimicrobial agent

[Term]
id: CHEBI:140310
name: phenyl acetates
def: "An acetate ester obtained by formal condensation of the carboxy group of acetic acid with the hydroxy group of any phenol." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:47622 ! acetate ester

[Term]
id: CHEBI:140317
name: phenyl sulfate oxoanion
def: "An aryl sulfate oxoanion obtained by deprotonation of the sulfo group of any phenyl sulfate; major species at pH 7.3." []
is_a: CHEBI:139371 ! aryl sulfate oxoanion

[Term]
id: CHEBI:140322
name: triketone
def: "A compound that contains three ketone functionalities." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:140323
name: beta-triketone
def: "A triketone in which the each ketone functionality is located β- to the other two." []
is_a: CHEBI:140322 ! triketone

[Term]
id: CHEBI:140324
name: primary carboxamide
def: "A carboxamide resulting from the formal condensation of a carboxylic acid with ammonia; formula RC(=O)NH<small><sub>2</sub></small>." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:140325
name: secondary carboxamide
def: "A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR<small><sup>1</small></sup>." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:140326
name: tertiary carboxamide
def: "A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR<small><sup>1</small></sup>R<small><sup>2</small></sup>." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:140331
name: 4'-hydroxyflavanones
def: "Any hydroxyflavanone having a hydroxy substituent located at position 4'." []
is_a: CHEBI:24697 ! hydroxyflavanone

[Term]
id: CHEBI:140332
name: 4'-methoxyflavanones
def: "Any methoxyflavanone having a methoxy substituent located at position 4'." []
is_a: CHEBI:25240 ! methoxyflavanone

[Term]
id: CHEBI:140345
name: hydroxy polyunsaturated fatty acid
def: "Any polyunsaturated fatty acid carrying one or more hydroxy substituents." []
is_a: CHEBI:24654 ! hydroxy fatty acid
is_a: CHEBI:26208 ! polyunsaturated fatty acid
relationship: RO:0018034 CHEBI:131871 ! is protonated form of hydroxy polyunsaturated fatty acid anion

[Term]
id: CHEBI:140399
name: specialised pro-resolving mediator
def: "A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation." []
is_a: CHEBI:62488 ! signalling molecule
is_a: CHEBI:67079 ! anti-inflammatory agent

[Term]
id: CHEBI:140426
name: 2,4,6-trichlorophenolate
def: "A phenolate anion resulting from the deprotonation of the phenolic hydroxy group of 2,4,6-trichlorophenol." []
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0018033 CHEBI:28755 ! is deprotonated form of 2,4,6-trichlorophenol

[Term]
id: CHEBI:140489
name: tropomyosin-related kinase B receptor agonist
def: "An agonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF)." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:140499
name: kaolinite
def: "An aluminosilicate mineral with approximate chemical composition H<small><sub>2</sub></small>Al<small><sub>2</sub></small>Si<small><sub>2</sub></small>O<small><sub>8</sub></small>.H<small><sub>2</sub></small>O. Rocks that are rich in kaolinite are known as kaolin or china clay." []
is_a: CHEBI:48730 ! aluminosilicate mineral

[Term]
id: CHEBI:140503
name: kaolin
def: "An aluminosilicate soft white mineral named after the hill in China (Kao-ling) from which it was mined for centuries. In its natural state kaolin is a white, soft powder consisting principally of the mineral kaolinite, and varying amounts of other minerals such as muscovite, quartz, feldspar, and anatase. It is used in the manufacture of china and porcelain and also widely used in the production of paper, rubber, paint, drying agents, and many other products." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48730 ! aluminosilicate mineral
is_a: CHEBI:51175 ! organoaluminium compound
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:140499 ! has part kaolinite
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug
relationship: RO:0000087 CHEBI:75324 ! has role excipient

[Term]
id: CHEBI:140535
name: TRPV1 agonist
def: "An agonist at the transient receptor potential vanilloid 1 (TRPV1)." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:140601
name: fatty acid 4:0
def: "Any saturated fatty acid containing 4 carbons." []
is_a: CHEBI:26666 ! short-chain fatty acid
relationship: RO:0018034 CHEBI:78115 ! is protonated form of fatty acid anion 4:0

[Term]
id: CHEBI:140602
name: Arabidopsis thaliana metabolite
def: "Any plant metabolite that is produced by <em>Arabidopsis thaliana</em>." []
is_a: CHEBI:76924 ! plant metabolite

[Term]
id: CHEBI:140921
name: Hedgehog signaling pathway inhibitor
def: "Any pathway inhibitor that inhibits the Hedgehog signalling pathway." []
is_a: CHEBI:76932 ! pathway inhibitor

[Term]
id: CHEBI:140922
name: glioma-associated oncogene inhibitor
def: "An inhibitor of any of the glioma-associated oncogene (GLI) proteins." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:140948
name: fatty acid 18:1
def: "Any monounsaturated fatty acid containing 18 carbons and 1 double bond." []
is_a: CHEBI:35366 ! fatty acid

[Term]
id: CHEBI:140949
name: fatty acid 18:2
def: "Any polyunsaturated fatty acid containing 18 carbons and 2 double bonds." []
is_a: CHEBI:35366 ! fatty acid

[Term]
id: CHEBI:141153
name: quinone outside inhibitor
def: "A mitochondrial cytochrome-<em>b</em><em>c</em><small><sub>1</sub></small> complex inhibitor that acts at the Quinone 'outer' (Q<small><sub>o</sub></small>) binding site of the cytochrome-<em>b</em><em>c</em><small><sub>1</sub></small> complex." []
is_a: CHEBI:24127 ! fungicide
is_a: CHEBI:38499 ! mitochondrial cytochrome-bc1 complex inhibitor

[Term]
id: CHEBI:141347
name: pinoxaden acid
def: "An organic hydroxy compound resulting from the hydrolysis of the the pivalate ester group of the proherbicide pinoxaden." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:136684 ! pyrazolooxadiazepine
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:33822 ! organic hydroxy compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:141349
name: 3,6-dichloro-2-methoxybenzoate
def: "A member of the class of benzoates resuting from the deprotonation of the carboxy group of 3,6-dichloro-2-methoxybenzoic acid (dicamba). Major microspecies at pH 7.3" []
is_a: CHEBI:22718 ! benzoates
relationship: RO:0018033 CHEBI:81856 ! is deprotonated form of dicamba
relationship: RO:0018038 CHEBI:59128 ! has functional parent O-methylsalicylate

[Term]
id: CHEBI:141455
name: Tyr-Asp
def: "A dipeptide obtained by formal condensation of the carboxy group of <small>L</small>-tyrosine with the amino group of <small>L</small>-aspartic acid." []
is_a: CHEBI:46761 ! dipeptide
relationship: RO:0018038 CHEBI:17053 ! has functional parent L-aspartic acid
relationship: RO:0018038 CHEBI:17895 ! has functional parent L-tyrosine

[Term]
id: CHEBI:141474
name: diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
def: "A diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphorothioyl)thio group." []
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:51307 ! diester
relationship: RO:0018038 CHEBI:195233 ! has functional parent diethyl 2-sulfanylbutanedioate

[Term]
id: CHEBI:141475
name: (R)-malathion
def: "A diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate that is the <i>R</i>-enantiomer of malathion." []
is_a: CHEBI:141474 ! diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
relationship: RO:0018039 CHEBI:141476 ! is enantiomer of (S)-malathion

[Term]
id: CHEBI:141476
name: (S)-malathion
def: "A diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate that is the <i>S</i>-enantiomer of malathion." []
is_a: CHEBI:141474 ! diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
relationship: RO:0018039 CHEBI:141475 ! is enantiomer of (R)-malathion

[Term]
id: CHEBI:141487
name: N(4)-\{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl\}pentane-1,4-diamine
def: "An aminoquinoline that is 8-aminoquinoline which is substituted by methoxy groups at positions 2 and 6, a methyl group at position 4, and a <em>m</em>-(trifluoromethyl)phenoxy group at position 5, and in which the amino substituent at position 8 is itself substituted by a 5-aminopentan-2-yl group." []
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36709 ! aminoquinoline
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes

[Term]
id: CHEBI:141488
name: (R)-tafenoquine
def: "A <em>N</em><small><sup>4</small></sup>-{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl}pentane-1,4-diamine that has <i>R</i> configuration." []
is_a: CHEBI:141487 ! N(4)-{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl}pentane-1,4-diamine
relationship: RO:0018039 CHEBI:141489 ! is enantiomer of (S)-tafenoquine

[Term]
id: CHEBI:141489
name: (S)-tafenoquine
def: "A <em>N</em><small><sup>4</small></sup>-{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl}pentane-1,4-diamine that has <i>S</i> configuration." []
is_a: CHEBI:141487 ! N(4)-{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl}pentane-1,4-diamine
relationship: RO:0018039 CHEBI:141488 ! is enantiomer of (R)-tafenoquine

[Term]
id: CHEBI:141493
name: carboxybiphenyl
def: "Any member of the class of biphenyls that has one or more carboxy groups attached to the biphenyl skeleton." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:22888 ! biphenyls

[Term]
id: CHEBI:141498
name: hemiaminal ether
def: "An organic amino compound that is a hemiaminal in which the hydrogen atom of the hydroxy group has been replaced by an organyl group. General formula: R2C(OR')NR2 ( R ≠ H ). Also known as α-amino ethers." []
is_a: CHEBI:36963 ! organooxygen compound
is_a: CHEBI:50047 ! organic amino compound
relationship: RO:0018038 CHEBI:73080 ! has functional parent hemiaminal

[Term]
id: CHEBI:141668
name: L-tyrosinal(1+)
def: "A primary ammonium ion resulting from the protonation of the amino group of <small>L</small>-tyrosinal." []
is_a: CHEBI:65296 ! primary ammonium ion
relationship: RO:0018034 CHEBI:46209 ! is protonated form of L-tyrosinal

[Term]
id: CHEBI:142118
name: imidazobenzodiazepine
def: "Any organic heterotricyclic compound that is any benzodiazepine which is <em>ortho</em>-fused with a imidazole." []
is_a: CHEBI:22720 ! benzodiazepine
is_a: CHEBI:26979 ! organic heterotricyclic compound

[Term]
id: CHEBI:142163
name: 24G7 epitope
def: "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXα, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24433 ! group
relationship: RO:0000087 CHEBI:53000 ! has role epitope

[Term]
id: CHEBI:142348
name: hexahydronaphthalenes
def: "Any carbobycyclic compound that is an hexahydronaphthalene or a compound obtained from an hexahydronaphthalene by formal substitution of one or more hydrogens." []
is_a: CHEBI:36785 ! carbobicyclic compound

[Term]
id: CHEBI:142355
name: purines D-ribonucleoside
def: "A purine ribonucleoside that is a purine derivative attached to a β-<small>D</small>-ribofuranosyl residue at position 9 via a glycosidic (<em>N</em>-glycosyl) linkage." []
is_a: CHEBI:26399 ! purine ribonucleoside
relationship: RO:0018038 CHEBI:26386 ! has functional parent purine nucleobase
relationship: RO:0018038 CHEBI:47013 ! has functional parent D-ribofuranose

[Term]
id: CHEBI:142468
name: 1,2-dichloropropane
def: "A chloroalkane that is propane in which a hydrogen from each of two adjacent carbons has been replaced by chlorines." []
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:23128 ! chloroalkane

[Term]
id: CHEBI:142469
name: (R)-1,2-dichloropropane
def: "A 1,2-dichloropropane that has <i>R</i> configuration." []
is_a: CHEBI:142468 ! 1,2-dichloropropane
relationship: RO:0018039 CHEBI:142471 ! is enantiomer of (S)-1,2-dichloropropane

[Term]
id: CHEBI:142471
name: (S)-1,2-dichloropropane
def: "A 1,2-dichloropropane that has <i>S</i> configuration." []
is_a: CHEBI:142468 ! 1,2-dichloropropane
relationship: RO:0018039 CHEBI:142469 ! is enantiomer of (R)-1,2-dichloropropane

[Term]
id: CHEBI:142513
name: oxime anion
def: "A organic ion resulting from the deprotonation of the hydroxy group of any oxime." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:25750 ! is deprotonated form of oxime

[Term]
id: CHEBI:142544
name: tamsulosin(1+)
def: "A secondary ammonium ion resulting from the protonation of the secondary amino group of tamsulosin. The major species at pH 7.3." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:9398 ! is protonated form of tamsulosin
relationship: RO:0018039 CHEBI:142549 ! is enantiomer of ent-tamsulosin(1+)

[Term]
id: CHEBI:142546
name: 5-(2-\{[2-(2-ethoxyphenoxy)ethyl]amino\}propyl)-2-methoxybenzenesulfonamide
def: "A secondary amino compound that is ammonia in which nitrogen is substituted by a 1-(4-methoxy-3-sulfamoylphenyl)propan-2-yl group and a 2-(2-ethoxyphenoxy)ethyl group." []
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:50995 ! secondary amino compound

[Term]
id: CHEBI:142548
name: ent-tamsulosin
def: "A 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide that has (<i>S</i>)-configuration. The enantiomer of tamsulosin." []
is_a: CHEBI:142546 ! 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide
relationship: RO:0018033 CHEBI:142549 ! is deprotonated form of ent-tamsulosin(1+)
relationship: RO:0018039 CHEBI:9398 ! is enantiomer of tamsulosin

[Term]
id: CHEBI:142549
name: ent-tamsulosin(1+)
def: "A secondary ammonium ion resulting from the secondary amino group of <em>ent</em>-tamsulosin. The major species at pH 7.3." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:142548 ! is protonated form of ent-tamsulosin
relationship: RO:0018039 CHEBI:142544 ! is enantiomer of tamsulosin(1+)

[Term]
id: CHEBI:142593
name: 4-hydroxynonenal
def: "A monounsaturated fatty aldehyde that is nonanal that has undergone dehydrogenation to introduce a double bond at any position in the aliphatic chain and in which a hydrogen at position 4 has been replaced by a hydroxy group." []
is_a: CHEBI:50413 ! hydroxyaldehyde
is_a: CHEBI:61870 ! monounsaturated fatty aldehyde

[Term]
id: CHEBI:142622
name: primary fatty alcohol
def: "Any fatty alcohol in which the hydroxy group is attached to a methylene (CH<small><sub>2</sub></small>) group." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:24026 ! fatty alcohol

[Term]
id: CHEBI:142669
name: asulam(1-)
def: "An organic nitrogen anion resulting from the deprotonation of the <em>N</em>-acylsulfonamide moiety of asulam. The conjugate base of asulam." []
is_a: CHEBI:50335 ! organic nitrogen anion
relationship: RO:0018033 CHEBI:81696 ! is deprotonated form of asulam

[Term]
id: CHEBI:142708
name: tigecycline(1+)
def: "An ammonium ion that is the conjugate acid of tigecycline; major species at pH 7.3." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:149836 ! is protonated form of tigecycline

[Term]
id: CHEBI:142782
name: TRPV channel modulator
def: "Any transient receptor potential (TRP) channel modulator that modulates the TRPV channels (V = vanilloid). There is strong evidence that action at one or more of this class of proteins is responsible for the insecticidal action of pymetrozine, pyrifluquinazon, and afidopyropen." []
is_a: CHEBI:142783 ! TRP channel modulator

[Term]
id: CHEBI:142783
name: TRP channel modulator
def: "An agent that modulates the passage of cations through the transient receptor potential (TRP) channels." []
is_a: CHEBI:38632 ! membrane transport modulator

[Term]
id: CHEBI:142839
name: enolate
def: "An organic anion arising from deprotonation of the hydroxy group of an enol." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:33823 ! is deprotonated form of enol

[Term]
id: CHEBI:142921
name: 3-phenylprop-2-enal
def: "A member of the class of cinnamaldehydes that is prop-2-enal in which a hydrogen at position 3 has been replaced by a phenyl group. The configuration of the double bond is not specified; the name \"cinnamaldehyde\" is widely used to refer to the <i>E</i> (<i>trans</i>) isomer." []
is_a: CHEBI:23245 ! cinnamaldehydes

[Term]
id: CHEBI:143079
name: D-leucine zwitterion
def: "A <small>D</small>-α-amino acid zwitterion arising from the transfer of a proton from the carboxy to the amino group of <small>D</small>-leucine; major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:28225 ! is tautomer of D-leucine

[Term]
id: CHEBI:143081
name: D-homoserine zwitterion
def: "A <small>D</small>-α-amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of <small>D</small>-homoserine; major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:30654 ! is tautomer of D-homoserine

[Term]
id: CHEBI:143084
name: organometalloidal compound
def: "A compound having bonds between one or more metalloid atoms and one or more carbon atoms of an organyl group." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:143125
name: monosodium urate
def: "Monosodium urate (MSU) or uric acid is the aetiological agent of the acute inflammatory condition gout." []
is_a: CHEBI:35875 ! imidazopyrimidine

[Term]
id: CHEBI:143129
name: primary fatty amide
def: "A primary carboxamide RC(=O)NH<small><sub>2</sub></small> resultng from the formal condensation of the carboxy group of a fatty acid with ammonia." []
is_a: CHEBI:140324 ! primary carboxamide
is_a: CHEBI:29348 ! fatty amide

[Term]
id: CHEBI:14321
name: glutamate(1-)
def: "An α-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:18237 ! is deprotonated form of glutamic acid
relationship: RO:0018034 CHEBI:29987 ! is protonated form of glutamate(2-)

[Term]
id: CHEBI:143212
name: thienopyrimidine
def: "A class of aromatic heterobicyclic compounds each of which contains a pyrimidine ring <em>ortho</em> fused to a 5-membered thiophene ring." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:143274
name: indole-3-butyrate
def: "An  indol-3-yl carboxylic acid anion that is the conjugate base of  indole-3-butyric acid, arising from the deprotonation of the carboxy group." []
is_a: CHEBI:38468 ! indol-3-yl carboxylic acid anion
relationship: RO:0018033 CHEBI:33070 ! is deprotonated form of indole-3-butyric acid

[Term]
id: CHEBI:143277
name: 4-(2,4-dichlorophenoxy)butanoate
def: "A monocarboxylic acid anion resulting from the dprotonation of the carboxy group of 4-(2,4-dichlorophenoxy)butanoic acid (2,4-DB). The major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0018033 CHEBI:73173 ! is deprotonated form of 2,4-DB

[Term]
id: CHEBI:143563
name: 3beta-hydroxy-4,4-dimethylsteroid
def: "Any 3β-hydroxy steroid which is substituted by two methyl groups at position 4." []
is_a: CHEBI:36836 ! 3beta-hydroxy steroid

[Term]
id: CHEBI:143593
name: beta-galactosylceramide
is_a: CHEBI:36498 ! galactosylceramide

[Term]
id: CHEBI:143597
name: pentanol
def: "A fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of five carbon atoms." []
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:197507 ! short-chain fatty alcohol
is_a: CHEBI:50584 ! alkyl alcohol
relationship: RO:0018040 CHEBI:37830 ! has parent hydride pentane

[Term]
id: CHEBI:143658
name: vincristine(2+)
def: "A vinca alkaloid cation resulting from the protonation of the two tertiary amino groups of vincristine. Major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60082 ! vinca alkaloid cation
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018034 CHEBI:28445 ! is protonated form of vincristine

[Term]
id: CHEBI:143729
name: tris(1,3-dichloropropan-2-yl) phosphate
is_a: CHEBI:37562 ! trialkyl phosphate

[Term]
id: CHEBI:143794
name: 3,5,6-trichloro-2-pyridinol
def: "A hydroxypyridine that is pyridin-2-ol substituted by chloro groups at positions 3,5 and 6. It is a metabolite of the agrochemical chlorpyrifos." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24745 ! hydroxypyridine
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018036 CHEBI:83490 ! is tautomer of 3,5,6-trichloropyridine-2-one

[Term]
id: CHEBI:143898
name: (R,R)-chrysanthemol
def: "A chrysanthemol in which both chiral centres have <i>R</i> configuration." []
is_a: CHEBI:81217 ! chrysanthemol

[Term]
id: CHEBI:143899
name: (R,R)-chrysanthemal
def: "An aldehyde resulting from the formal oxidation of the hydroxy group of (<i>R</i>,<i>R</i>)-chrysanthemol." []
is_a: CHEBI:25409 ! monoterpenoid
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:59768 ! aliphatic aldehyde
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0018038 CHEBI:143898 ! has functional parent (R,R)-chrysanthemol

[Term]
id: CHEBI:143900
name: (R,R)-chrysanthemate
def: "A monocarboxylic acid anion resulting from the deprotonation of the carboxy group of (+)-<i>trans</i>-chrysanthemic acid. The major species at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:39100 ! is deprotonated form of (+)-trans-chrysanthemic acid

[Term]
id: CHEBI:144093
name: N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
def: "A member of the class of (trifluoromethyl)benzenes that is 4-amino-2-(trifluoromethyl)benzonitrile in which one of the amino hydrogens is substituted by a 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoyl group." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35850 ! sulfone
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
is_a: CHEBI:83575 ! monofluorobenzenes

[Term]
id: CHEBI:144094
name: (S)-bicalutamide
def: "A <em>N</em>-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide that is the (<i>S</i>)-enantiomer of bicalutamide." []
is_a: CHEBI:144093 ! N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
relationship: RO:0018039 CHEBI:39589 ! is enantiomer of (R)-bicalutamide

[Term]
id: CHEBI:144441
name: triacsin C
def: "A nitroso compound that is <em>N</em>-undecylnitrous hydrazide carrying double bonds at positions 1,2,4, and 7. It is a long-chain fatty acyl CoA synthetase inhibitor and interferes with lipid metabolism by inhibiting the de novo synthesis of glycerolipids and cholesterol esters." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35800 ! nitroso compound
is_a: CHEBI:38532 ! hydrazone
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0000087 CHEBI:144455 ! has role EC 3.1.1.64 (retinoid isomerohydrolase) inhibitor
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:83157 ! has role EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor

[Term]
id: CHEBI:144455
name: EC 3.1.1.64 (retinoid isomerohydrolase) inhibitor
def: "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of retinoid isomerohydrolase (EC 3.1.1.64)." []
is_a: CHEBI:76773 ! EC 3.1.1.* (carboxylic ester hydrolase) inhibitor

[Term]
id: CHEBI:144643
name: indoxyl sulfate(1-)
def: "An  aryl sulfate oxoanion that is the conjugate base of indoxyl sulfate, obtained by deprotonation of the sulfo group; major species at pH 7.3." []
is_a: CHEBI:139371 ! aryl sulfate oxoanion
relationship: RO:0018033 CHEBI:43355 ! is deprotonated form of indoxyl sulfate

[Term]
id: CHEBI:144644
name: a tetracycline zwitterion
is_a: CHEBI:26895 ! tetracyclines

[Term]
id: CHEBI:144987
name: sphingosine-1-phosphate receptor antagonist
def: "An antagonist that binds to and blocks sphingosine 1-phosphate receptors, a class of G protein-coupled receptors that are targets of the lipid signalling molecule sphingosine-1-phosphate (S1P)." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:145047
name: antispermatogenic agent
def: "An agent that destroy spermatozoa in the male genitalia and block spermatogenesis." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:145372
name: gilteritinib
def: "A member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC<small><sub>50</sub></small> = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation." []
is_a: CHEBI:140324 ! primary carboxamide
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:38314 ! pyrazines
is_a: CHEBI:46920 ! N-methylpiperazine
is_a: CHEBI:46942 ! oxanes
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:62434 ! has role EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:145403
name: (R)-diclofop
def: "A 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid that is the (<i>R</i>)-enantiomer of diclofop." []
is_a: CHEBI:145406 ! 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0018039 CHEBI:145404 ! is enantiomer of (S)-diclofop

[Term]
id: CHEBI:145404
name: (S)-diclofop
def: "A 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid that is the (<i>S</i>)-enantiomer of diclofop." []
is_a: CHEBI:145406 ! 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid
relationship: RO:0018039 CHEBI:145403 ! is enantiomer of (R)-diclofop

[Term]
id: CHEBI:145406
name: 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid
def: "An aromatic ether that is 2-(4-hydroxyphenoxy)propanoic acid in which the hydrogen of the hydroxy group at position 4 has been substituted by a 2,4-dichlorophenyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:46786 ! diether

[Term]
id: CHEBI:145412
name: methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate
def: "A methyl ester resulting from the formal condensation of the carboxylic acid group of 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid with methanol." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:46786 ! diether

[Term]
id: CHEBI:145413
name: (R)-diclofop-methyl
def: "A methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate that is the (<i>R</i>)-enantiomer of diclofop-methyl." []
is_a: CHEBI:145412 ! methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate
relationship: RO:0018039 CHEBI:145414 ! is enantiomer of (S)-diclofop-methyl

[Term]
id: CHEBI:145414
name: (S)-diclofop-methyl
def: "A methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate that is the (<i>S</i>)-enantiomer of diclofop-methyl." []
is_a: CHEBI:145412 ! methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate
relationship: RO:0018039 CHEBI:145413 ! is enantiomer of (R)-diclofop-methyl

[Term]
id: CHEBI:145555
name: macropolylide
def: "Macrolides (macrocyclic lactones) in which the macrocyclic ring contains more than one ester linkage. Macropolylides include macrodiolides, macrotriolides, macrotetrolides and macropentolides, each containing di-, tri-, tetra-, and penta- ester linkages, respectively, in one macrocyclic ring. Macrocyclic lactones containing nitrogen in their skeletons (azamacrolides and macrolide lactams) and also containing oxazole or thiazole in their skeletons are known in nature." []
is_a: CHEBI:25106 ! macrolide

[Term]
id: CHEBI:145556
name: macrodiolide
def: "A macropolylide which contains two ester linkages in one macrocyclic ring." []
is_a: CHEBI:145555 ! macropolylide

[Term]
id: CHEBI:145565
name: macrolide lactam
def: "A macrolide in which the macrocyclic lactone ring includes an amide group." []
is_a: CHEBI:24995 ! lactam
is_a: CHEBI:25106 ! macrolide

[Term]
id: CHEBI:145810
name: insulin
def: "A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the β cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies." []
is_a: CHEBI:15841 ! polypeptide
is_a: CHEBI:24533 ! heterodetic cyclic peptide
is_a: CHEBI:25905 ! peptide hormone

[Term]
id: CHEBI:145932
name: (S)-2-methylbutanoate
def: "A branched-chain saturated fatty acid anion resulting from the deprotonation of the carboxy group of (<i>S</i>)-2-methylbutanoic acid. The major species at pH 7.3." []
is_a: CHEBI:58951 ! short-chain fatty acid anion
is_a: CHEBI:58956 ! branched-chain saturated fatty acid anion
is_a: CHEBI:83976 ! 2-methyl fatty acid anion
relationship: RO:0018033 CHEBI:38655 ! is deprotonated form of (S)-2-methylbutyric acid

[Term]
id: CHEBI:145947
name: antiatherosclerotic agent
def: "A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with <a href=\"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:50855\" target=\"_blank\">antiatherogenic agent</a>." []
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:145994
name: remdesivir
def: "A carboxylic ester resulting from the formal condensation of the carboxy group of <em>N</em>-[(<i>S</i>)-{[(2<i>R</i>,3<i>S</i>,4<i>R</i>,5<i>R</i>)-5-(4-aminopyrrolo[2,1-<em>f</em>][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-<small>L</small>-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent <em>in vitro</em> antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:27577 ! phosphoramidate ester
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:37086 ! C-nucleoside
is_a: CHEBI:46874 ! alpha-amino acid ester
is_a: CHEBI:88341 ! pyrrolotriazine
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0018038 CHEBI:147281 ! has functional parent GS-441524

[Term]
id: CHEBI:146144
name: L-Fucp-(1->2)-[D-Galp-(1->3)]-D-Galp
def: "Any branched trisaccharide consisting of <small>D</small>-galactopyranose having an <small>L</small>-fucosyl residue at the 2-position and a <small>D</small>-galactosyl residue at the 3-position." []
is_a: CHEBI:27150 ! trisaccharide

[Term]
id: CHEBI:146176
name: levomethorphan
def: "A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2<em>H</em>-10,4a-(epiminoethano)phenanthrene in which the stereocenters at positions 4a, 10 and 10a have <i>R</i>-configuration. It is a prodrug of levorphanol and a strong narcotic analgesic, and listed as a schedule II controlled substance." []
is_a: CHEBI:146178 ! 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0018038 CHEBI:6444 ! has functional parent Levorphanol
relationship: RO:0018039 CHEBI:4470 ! is enantiomer of dextromethorphan

[Term]
id: CHEBI:146178
name: 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
def: "An organic heterotetracyclic compound that is 1,3,4,9,10,10a-hexahydro-2<em>H</em>-10,4a-(epiminoethano)phenanthrene which is substituted by a methoxy group at position 6 and a methyl group at position 11." []
is_a: CHEBI:25418 ! morphinane alkaloid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38163 ! organic heterotetracyclic compound
is_a: CHEBI:83818 ! morphinane-like compound

[Term]
id: CHEBI:146243
name: JWH-133
def: "A dibenzopyran that is <a href=\"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:66964\" target=\"_blank\">Δ<small><sup>9</small></sup>-tetrahydrocannabinol</a> which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB<small><sub>2</sub></small> receptor agonist." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38920 ! benzochromene
is_a: CHEBI:39203 ! dibenzopyran
relationship: RO:0000087 CHEBI:146246 ! has role CB2 receptor agonist
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor

[Term]
id: CHEBI:146246
name: CB2 receptor agonist
def: "A cannabinoid receptor agonist that binds to and activates type 2 cannabinoid receptors." []
is_a: CHEBI:67072 ! cannabinoid receptor agonist

[Term]
id: CHEBI:146270
name: oneirogen
def: "Any substance that produces or enhances dream-like states of consciousness." []
is_a: CHEBI:35471 ! psychotropic drug

[Term]
id: CHEBI:146281
name: anthracenone
def: "Any member of the class of anthracenes in which the anthracene moiety is substituted by an oxo group." []
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:46955 ! anthracenes

[Term]
id: CHEBI:146291
name: 11-HPETE(1-)
is_a: CHEBI:59720 ! HPETE anion

[Term]
id: CHEBI:146293
name: 9-HPODE(1-)
is_a: CHEBI:131862 ! HPODE(1-)

[Term]
id: CHEBI:147281
name: GS-441524
def: "A C-nucleoside analog that is (2<i>R</i>,3<i>R</i>,4<i>S</i>,5<i>R</i>)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-<em>f</em>][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:37086 ! C-nucleoside
is_a: CHEBI:88341 ! pyrrolotriazine
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite

[Term]
id: CHEBI:147285
name: EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
def: "An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69)." []
is_a: CHEBI:76796 ! EC 3.4.22.* (cysteine endopeptidase) inhibitor

[Term]
id: CHEBI:148436
name: nitrification inhibitor
def: "Any inhibitor added to nitrogen fertilizers which can reduce the rate at which ammonium is converted to nitrate. Under appropriate conditions, this can help reduce nitrogen losses through denitrification and leaching." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:149484
name: chloroquine(2+)
def: "A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug chloroquine. It is the major species at pH 7.3." []
is_a: CHEBI:137982 ! tertiary ammonium ion
is_a: CHEBI:52837 ! quinolinium ion
relationship: RO:0018034 CHEBI:3638 ! is protonated form of chloroquine

[Term]
id: CHEBI:149500
name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative
def: "An entity derived from (4<i>Z</i>,7<i>Z</i>,10<i>Z</i>,13<i>Z</i>,16<i>Z</i>,19<i>Z</i>)-docosahexaenoic acid where the R is not defined." []
is_a: CHEBI:61697 ! fatty acid derivative

[Term]
id: CHEBI:149504
name: losartan(1-)
def: "An organic anion that is the conjugate base of losartan, obtained from the deprotonation of the tetrazole NH group. Major species at pH 7.3." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:6541 ! is deprotonated form of losartan

[Term]
id: CHEBI:149509
name: candesartan(2-)
def: "A monocarboxylic acid anion resulting from the deprotonation of the tetrazole NH group and carboxy group of candesartan. It is the major species at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:3347 ! is deprotonated form of candesartan

[Term]
id: CHEBI:149552
name: emetic
def: "Any agent that induces nausea and vomiting." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:149553
name: anticoronaviral agent
def: "Any antiviral agent which inhibits the activity of coronaviruses." []
is_a: CHEBI:22587 ! antiviral agent

[Term]
id: CHEBI:149564
name: hydroxychloroquine(2+)
def: "A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug hydroxychloroquine. It is the major species at pH 7.3." []
is_a: CHEBI:137982 ! tertiary ammonium ion
is_a: CHEBI:52837 ! quinolinium ion
relationship: RO:0018034 CHEBI:5801 ! is protonated form of hydroxychloroquine

[Term]
id: CHEBI:149673
name: (1S,2R)-ephedrine(1+)
def: "An organic cation obtained by protonation of the secondary amino function of (1<i>S</i>,2<i>R</i>)-ephedrine; major species at pH 7.3." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018039 CHEBI:57295 ! is enantiomer of (-)-ephedrinium

[Term]
id: CHEBI:149689
name: D-dopa zwitterion
def: "An amino acid zwitterion obtained from the transfer of a proton from the carboxy group to the amino group of <small>D</small>-dopa. Major microspecies at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:49169 ! is tautomer of D-dopa
relationship: RO:0018039 CHEBI:57504 ! is enantiomer of L-dopa zwitterion

[Term]
id: CHEBI:14973
name: pyrazole
def: "A monocyclic heteroarene that is a five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 2." []
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:35555 ! mancude organic heteromonocyclic parent
relationship: RO:0018034 CHEBI:38596 ! is protonated form of pyrazolide

[Term]
id: CHEBI:149836
name: tigecycline
def: "Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (<em>N</em>-<em>tert</em>-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms." []
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:26895 ! tetracyclines
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0018033 CHEBI:142708 ! is deprotonated form of tigecycline(1+)

[Term]
id: CHEBI:150013
name: emodin anthrone
def: "A member of the class of anthracenones that is anthracen-9(10<em>H</em>)-one which carries a methyl group at position 6 and hydroxy groups at positions 1, 3 and 8, respectively. It is an intermediate precursor in the synthesis of hypericin." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:146281 ! anthracenone
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite

[Term]
id: CHEBI:15022
name: electron donor
def: "A molecular entity that can transfer an electron to another molecular entity." []
is_a: CHEBI:17891 ! donor

[Term]
id: CHEBI:15035
name: retinal
def: "An enal that consists of 3,7-dimethyl-9-nona-2,4,6,8-tetraenal (double bond geometry unspecified) carrying a 2,6,6-trimethylcyclohex-1-en-1-yl group at the 9-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26534 ! retinals
is_a: CHEBI:51688 ! enal
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:15036
name: retinoate
is_a: CHEBI:139589 ! retinoid anion
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:26536 ! is deprotonated form of retinoic acid

[Term]
id: CHEBI:15040
name: retinyl palmitate
def: "A palmitate ester of retinol with undefined geometry about the C=C bonds." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25835 ! hexadecanoate ester
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0018038 CHEBI:50211 ! has functional parent retinol

[Term]
id: CHEBI:15138
name: sulfide(2-)
def: "A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide." []
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:29919 ! is deprotonated form of hydrosulfide

[Term]
id: CHEBI:15193
name: DL-tartrate(2-)
def: "A racemate comprising equimolar amounts of <small>D</small>- and <small>L</small>-tartrate(2−)." []
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:30924 ! has part L-tartrate(2-)
relationship: BFO:0000051 CHEBI:30927 ! has part D-tartrate(2-)
relationship: RO:0018033 CHEBI:35397 ! is deprotonated form of DL-tartrate(1-)

[Term]
id: CHEBI:15258
name: trichlorophenols
def: "Any chlorophenol derivative that contains three covalently bonded chlorine atoms." []
is_a: CHEBI:23150 ! chlorophenol
is_a: CHEBI:27096 ! trichlorobenzene

[Term]
id: CHEBI:15318
name: xanthine
def: "A purine nucleobase found in humans and other organisms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25810 ! oxopurine
is_a: CHEBI:26386 ! purine nucleobase
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018038 CHEBI:16235 ! has functional parent guanine

[Term]
id: CHEBI:15333
name: zeatin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38643 ! 6-isopentenylaminopurine
relationship: RO:0000087 CHEBI:23530 ! has role cytokinin

[Term]
id: CHEBI:15339
name: acceptor
def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:15343
name: acetaldehyde
def: "The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke." []
synonym: "ACETALDEHYDE" EXACT [PDBeChem]
synonym: "Acetaldehyde" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17478 ! aldehyde
relationship: RO:0000087 CHEBI:17654 ! has role electron acceptor
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor

[Term]
id: CHEBI:15346
name: coenzyme A
def: "A thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:20706 ! 6-aminopurines
is_a: CHEBI:231540 ! nucleotide derivative
is_a: CHEBI:29256 ! thiol
relationship: RO:0000087 CHEBI:23354 ! has role coenzyme
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:57287 ! is protonated form of coenzyme A(4-)
relationship: RO:0018038 CHEBI:44672 ! has functional parent 3'-phosphate-adenosine-5'-diphosphate

[Term]
id: CHEBI:15347
name: acetone
def: "A methyl ketone that consists of propane bearing an oxo group at C2." []
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:26292 ! propanones
is_a: CHEBI:51867 ! methyl ketone
is_a: CHEBI:73693 ! ketone body
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor

[Term]
id: CHEBI:15348
name: 2-hydroxy-2-methylpropanenitrile
synonym: "2-Hydroxy-2-methylpropanenitrile" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23437 ! cyanohydrin

[Term]
id: CHEBI:15354
name: choline
def: "A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23217 ! cholines
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:33284 ! has role nutrient
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite

[Term]
id: CHEBI:15355
name: acetylcholine
def: "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35287 ! acylcholine
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:24621 ! has role hormone
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38325 ! has role muscarinic agonist
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:15356
name: cysteine
def: "A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3." []
synonym: "Cysteine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:26834 ! sulfur-containing amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:50326 ! has part sulfanylmethyl group
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32458 ! is deprotonated form of cysteinium
relationship: RO:0018034 CHEBI:32456 ! is protonated form of cysteinate(1-)
relationship: RO:0018036 CHEBI:35237 ! is tautomer of cysteine zwitterion

[Term]
id: CHEBI:15361
name: pyruvate
def: "A 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, arising from deprotonation of the carboxy group." []
synonym: "2-oxopropanoate" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35179 ! 2-oxo monocarboxylic acid anion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32816 ! is deprotonated form of pyruvic acid
relationship: RO:0018038 CHEBI:17272 ! has functional parent propionate

[Term]
id: CHEBI:15365
name: acetylsalicylic acid
def: "A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity." []
synonym: "2-(ACETYLOXY)BENZOIC ACID" EXACT [PDBeChem]
is_a: CHEBI:140310 ! phenyl acetates
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:26596 ! salicylates
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:49023 ! has role prostaglandin antagonist
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:50629 ! has role cyclooxygenase 2 inhibitor
relationship: RO:0000087 CHEBI:50630 ! has role cyclooxygenase 1 inhibitor
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:73182 ! has role plant activator
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77425 ! has role EC 1.1.1.188 (prostaglandin-F synthase) inhibitor
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:13719 ! is protonated form of acetylsalicylate
relationship: RO:0018038 CHEBI:16914 ! has functional parent salicylic acid

[Term]
id: CHEBI:15366
name: acetic acid
def: "A simple monocarboxylic acid containing two carbons." []
synonym: "ACETIC ACID" EXACT [PDBeChem]
synonym: "Acetic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator
relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018034 CHEBI:30089 ! is protonated form of acetate

[Term]
id: CHEBI:15367
name: all-trans-retinoic acid
def: "A retinoic acid in which all four exocyclic double bonds have <i>E</i>- (<i>trans</i>-) geometry." []
is_a: CHEBI:12777 ! vitamin A
is_a: CHEBI:26536 ! retinoic acid
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50176 ! has role keratolytic drug
relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule
relationship: RO:0000087 CHEBI:63794 ! has role retinoid X receptor agonist
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:67198 ! has role retinoic acid receptor agonist
relationship: RO:0000087 CHEBI:67199 ! has role AP-1 antagonist
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018034 CHEBI:35291 ! is protonated form of all-trans-retinoate

[Term]
id: CHEBI:15368
name: acrolein
def: "An enal that is prop-2-ene with an oxo group at position 1." []
synonym: "Acrylaldehyde" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51688 ! enal
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite

[Term]
id: CHEBI:15369
name: actinomycin
def: "A large group of antibiotics isolated from various species of <em>Streptomyces</em> and characterised by having a substituted phenoxazine ring linked to two cyclic heterodetic peptides." []
is_a: CHEBI:23239 ! chromopeptide

[Term]
id: CHEBI:15377
name: water
def: "An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms" []
synonym: "WATER" EXACT [PDBeChem]
synonym: "Water" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33693 ! oxygen hydride
is_a: CHEBI:37176 ! mononuclear parent hydride
is_a: CHEBI:52625 ! inorganic hydroxy compound
relationship: RO:0000087 CHEBI:48360 ! has role amphiprotic solvent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:29412 ! is deprotonated form of oxonium
relationship: RO:0018034 CHEBI:16234 ! is protonated form of hydroxide

[Term]
id: CHEBI:15378
name: hydron
def: "The general name for the hydrogen nucleus, to be used without regard to the hydrogen nuclear mass (either for hydrogen in its natural abundance or where it is not desired to distinguish between the isotopes)." []
is_a: CHEBI:25414 ! monoatomic monocation
is_a: CHEBI:33251 ! monoatomic hydrogen
is_a: CHEBI:33252 ! atomic nucleus
is_a: CHEBI:60242 ! monovalent inorganic cation

[Term]
id: CHEBI:15379
name: dioxygen
synonym: "Oxygen" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:25362 ! elemental molecule
is_a: CHEBI:33263 ! diatomic oxygen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas
relationship: RO:0018033 CHEBI:29793 ! is deprotonated form of hydridodioxygen(1+)

[Term]
id: CHEBI:15407
name: (-)-ephedrine
def: "A  phenethylamine alkaloid that is 2-phenylethanamine substituted by a methyl group at the amino nitrogen and a methyl and a hydroxy group at position 2 and 1 respectively." []
is_a: CHEBI:25990 ! phenylethanolamines
is_a: CHEBI:38605 ! phenethylamine alkaloid
is_a: CHEBI:38976 ! alkylbenzene
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:57295 ! is deprotonated form of (-)-ephedrinium

[Term]
id: CHEBI:15421
name: perillyl aldehyde
def: "An aldehyde that is cyclohex-1-ene-1-carbaldehyde substituted by a prop-1-en-2-yl group at position 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:15422
name: ATP
def: "An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways." []
is_a: CHEBI:37045 ! purine ribonucleoside 5'-triphosphate
is_a: CHEBI:37096 ! adenosine 5'-phosphate
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:57299 ! is protonated form of ATP(3-)

[Term]
id: CHEBI:15428
name: glycine
def: "The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain." []
synonym: "Aminoacetic acid" EXACT [KEGG_COMPOUND]
synonym: "GLYCINE" EXACT [PDBeChem]
synonym: "Glycine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26650 ! serine family amino acid
is_a: CHEBI:83813 ! proteinogenic amino acid
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64570 ! has role EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor
relationship: RO:0000087 CHEBI:64571 ! has role NMDA receptor agonist
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64952 ! has role anti-HSV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32507 ! is deprotonated form of glycinium
relationship: RO:0018034 CHEBI:32508 ! is protonated form of glycinate
relationship: RO:0018036 CHEBI:57305 ! is tautomer of glycine zwitterion

[Term]
id: CHEBI:15429
name: hydroxylamine
def: "The simplest hydroxylamine, consisting of ammonia bearing a hydroxy substituent. It is an intermediate in the biological nitrification by microbes like bacteria." []
synonym: "Hydroxylamine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24709 ! hydroxylamines
relationship: RO:0000087 CHEBI:50566 ! has role nitric oxide donor
relationship: RO:0000087 CHEBI:59740 ! has role nucleophilic reagent
relationship: RO:0000087 CHEBI:63156 ! has role EC 1.1.3.13 (alcohol oxidase) inhibitor
relationship: RO:0000087 CHEBI:63157 ! has role EC 4.2.1.22 (cystathionine beta-synthase) inhibitor
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0000087 CHEBI:77090 ! has role EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:29772 ! is protonated form of hydroxyazanide
relationship: RO:0018034 CHEBI:29773 ! is protonated form of aminooxidanide
relationship: RO:0018040 CHEBI:16134 ! has parent hydride ammonia

[Term]
id: CHEBI:15440
name: squalene
def: "A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (<em>all-E</em>)-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35191 ! triterpene
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:15443
name: inulin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29084 ! (2->1)-beta-D-fructan
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:15555
name: prostaglandin D2
def: "A member of the class of  prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5<i>Z</i>,9α,13<i>E</i>,15<i>S</i>- stereoisomer)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26337 ! prostaglandins D
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:57406 ! is protonated form of prostaglandin D2(1-)

[Term]
id: CHEBI:15570
name: D-alanine
def: "The <small>D</small>-enantiomer of alanine." []
synonym: "D-Alanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16449 ! alanine
is_a: CHEBI:16733 ! D-alpha-amino acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:77881 ! has role EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
relationship: RO:0018033 CHEBI:32436 ! is deprotonated form of D-alaninium
relationship: RO:0018034 CHEBI:32435 ! is protonated form of D-alaninate
relationship: RO:0018036 CHEBI:57416 ! is tautomer of D-alanine zwitterion
relationship: RO:0018039 CHEBI:16977 ! is enantiomer of L-alanine

[Term]
id: CHEBI:15571
name: hydrazine
synonym: "Hydrazine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24631 ! hydrazines
is_a: CHEBI:35107 ! azane
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:77090 ! has role EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
relationship: RO:0018033 CHEBI:35324 ! is deprotonated form of hydrazinium(1+)
relationship: RO:0018034 CHEBI:30095 ! is protonated form of hydrazinide

[Term]
id: CHEBI:155837
name: tripeptide zwitterion
def: "A peptide zwitterion obtained from the tranfer of a proton from the carboxy group to the amino group of any tripeptide. It contains an equal number of positively-charged and negatively-charged functional groups. Major structure at pH 7.3." []
is_a: CHEBI:60466 ! peptide zwitterion
relationship: RO:0018036 CHEBI:47923 ! is tautomer of tripeptide

[Term]
id: CHEBI:155903
name: copper(II) phthalocyanine
def: "A metallophthalocyanine that is copper(2+) forming a coordination complex with phthalocyanine. It is a synthetic blue pigment which is used as a colorant in paints and dyes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:155908 ! copper tetrapyrrole
is_a: CHEBI:51585 ! metallophthalocyanine
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome

[Term]
id: CHEBI:155908
name: copper tetrapyrrole
is_a: CHEBI:33909 ! metallotetrapyrrole
is_a: CHEBI:37403 ! copper coordination entity

[Term]
id: CHEBI:155920
name: elemental gallium
def: "An element in the boron group of the periodic table with atomic number 31, atomic mass 69.723, M.P. 29.7646 C, and B.P. 2400 C." []
is_a: CHEBI:37111 ! gallium molecular entity

[Term]
id: CHEBI:155928
name: arterolane(1+)
def: "A primary ammonium ion that is the conjugate acid of arterolane, resulting from the protonation of the primary amino group. Major species at pH 7.3." []
is_a: CHEBI:65296 ! primary ammonium ion
relationship: RO:0018034 CHEBI:136054 ! is protonated form of arterolane

[Term]
id: CHEBI:155930
name: trioxolane
def: "An oxocycle that is a five-membered, saturated heterocycle which contains two carbon atoms and three oxygen atoms and includes any derivative of this compound." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:15595
name: malate(2-)
def: "A C4-dicarboxylate resulting from deprotonation of both carboxy groups of malic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25115 ! malate
is_a: CHEBI:61336 ! C4-dicarboxylate
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018038 CHEBI:30031 ! has functional parent succinate(2-)

[Term]
id: CHEBI:15603
name: L-leucine
def: "The <small>L</small>-enantiomer of leucine." []
synonym: "L-Leucine" EXACT [KEGG_COMPOUND]
synonym: "LEUCINE" EXACT [PDBeChem]
is_a: CHEBI:25017 ! leucine
is_a: CHEBI:26463 ! pyruvate family amino acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32620 ! is deprotonated form of L-leucinium
relationship: RO:0018034 CHEBI:32619 ! is protonated form of L-leucinate
relationship: RO:0018036 CHEBI:57427 ! is tautomer of L-leucine zwitterion
relationship: RO:0018039 CHEBI:28225 ! is enantiomer of D-leucine

[Term]
id: CHEBI:156062
name: chlorinated naphthalene
def: "A group of compounds based on the naphthalene ring system where one or more hydrogen atoms have been replaced by chlorine. The generic molecular formula is C<small><sub>10</sub></small>H<small><sub>8-n</sub></small>Cl<small><sub>n</sub></small>, where n = 1-8. There are 75 possible chlorinated naphthalenes and they are commonly used in the electrical industry and as additives." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0018040 CHEBI:16482 ! has parent hydride naphthalene

[Term]
id: CHEBI:15611
name: sarcosine
def: "A <em>N</em>-alkylglycine that is the <em>N</em>-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine." []
synonym: "SARCOSINE" EXACT [PDBeChem]
synonym: "Sarcosine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:21760 ! N-methyl-amino acid
is_a: CHEBI:21766 ! N-methylglycines
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:64588 ! has role glycine transporter 1 inhibitor
relationship: RO:0000087 CHEBI:64589 ! has role glycine receptor agonist
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:46842 ! is deprotonated form of sarcosinium
relationship: RO:0018034 CHEBI:46915 ! is protonated form of sarcosinate
relationship: RO:0018036 CHEBI:57433 ! is tautomer of sarcosine zwitterion

[Term]
id: CHEBI:156132
name: L-thialysinium
is_a: CHEBI:47910 ! S-substituted L-cysteine
relationship: RO:0018034 CHEBI:497734 ! is protonated form of L-thialysine

[Term]
id: CHEBI:156230
name: 1-naphthaleneacetate
def: "A monocarboxylic acid anion that is the conjugate base of 1-naphthaleneacetic acid, arising from the deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:32918 ! is deprotonated form of 1-naphthaleneacetic acid

[Term]
id: CHEBI:156303
name: colibactin
def: "A member of the class of 1,3-thiazoles that comprises of two units of 2-[(2-{6-[(2<i>S</i>)-2-methyl-3,4-dihydro-2<em>H</em>-pyrrol-5-yl]-5-oxo-4-azaspiro[2.4]hept-6-en-7-yl}acetamido)methyl]-1,3-thiazole-4-carboxylic acid linked together via the formal condensation of the carboxy groups. It is a secondary metabolite produced by certain strains of bacteria found in the human gut such as <em>Escherichia coli</em>. It has the ability to bind covalently to DNA and is strongly associated with colorectal cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:23763 ! pyrroline
is_a: CHEBI:26188 ! polyketide
is_a: CHEBI:35624 ! azaspiro compound
is_a: CHEBI:38418 ! 1,3-thiazoles
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:156473
name: cyclobutanes
def: "Cyclobutane and its derivatives formed by substitution." []
is_a: CHEBI:33598 ! carbocyclic compound

[Term]
id: CHEBI:156548
name: kainate(1-)
def: "A dicarboxylate resulting from deprotonation of both carboxy groups of kainic acid, and protonation of its amine group. Major species at pH 7.3." []
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:31746 ! is deprotonated form of kainic acid

[Term]
id: CHEBI:15671
name: L-tartaric acid
def: "The <small>L</small>-enantiomer of tartaric acid." []
is_a: CHEBI:15674 ! 2,3-dihydroxybutanedioic acid
is_a: CHEBI:61355 ! 3-hydroxy carboxylic acid
relationship: RO:0018034 CHEBI:35398 ! is protonated form of L-tartrate(1-)
relationship: RO:0018039 CHEBI:15672 ! is enantiomer of D-tartaric acid

[Term]
id: CHEBI:15672
name: D-tartaric acid
def: "The <small>D</small>-enantiomer of tartaric acid." []
is_a: CHEBI:15674 ! 2,3-dihydroxybutanedioic acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:35399 ! is protonated form of D-tartrate(1-)
relationship: RO:0018039 CHEBI:15671 ! is enantiomer of L-tartaric acid

[Term]
id: CHEBI:15674
name: 2,3-dihydroxybutanedioic acid
def: "A tetraric acid that is butanedioic acid substituted by hydroxy groups at positions 2 and 3." []
is_a: CHEBI:26933 ! tetraric acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:48929 ! is protonated form of 3-carboxy-2,3-dihydroxypropanoate

[Term]
id: CHEBI:15676
name: allantoin
def: "An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24628 ! imidazolidine-2,4-dione
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018036 CHEBI:74345 ! is tautomer of 1-(5-hydroxy-2-oxo-2,3-dihydroimidazol-4-yl)urea
relationship: RO:0018038 CHEBI:27612 ! has functional parent hydantoin

[Term]
id: CHEBI:15688
name: acetoin
def: "A methyl ketone that is butan-2-one substituted by a hydroxy group at position 3." []
synonym: "3-Hydroxybutan-2-one" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:2468 ! secondary alpha-hydroxy ketone
is_a: CHEBI:51867 ! methyl ketone
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:15693
name: aldose
def: "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]<small><sub><em>n</em></sub></small>C(=O)H, <em>n</em> ≥ 2) and their intramolecular hemiacetals." []
is_a: CHEBI:35381 ! monosaccharide

[Term]
id: CHEBI:15699
name: L-homoserine
def: "The <small>L</small>-enantiomer of homoserine." []
synonym: "L-HOMOSERINE" EXACT [PDBeChem]
synonym: "L-Homoserine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:30653 ! homoserine
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018036 CHEBI:57476 ! is tautomer of L-homoserine zwitterion
relationship: RO:0018039 CHEBI:30654 ! is enantiomer of D-homoserine

[Term]
id: CHEBI:15702
name: terephthalic acid
def: "A benzenedicarboxylic acid carrying carboxy groups at positions 1 and 4. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and isophthalic acids." []
is_a: CHEBI:26094 ! benzenedicarboxylic acid
relationship: RO:0018034 CHEBI:30801 ! is protonated form of terephthalate(1-)

[Term]
id: CHEBI:15705
name: L-alpha-amino acid
def: "Any α-amino acid having <small>L</small>-configuration at the α-carbon." []
is_a: CHEBI:33704 ! alpha-amino acid
relationship: RO:0018034 CHEBI:59814 ! is protonated form of L-alpha-amino acid anion
relationship: RO:0018036 CHEBI:59869 ! is tautomer of L-alpha-amino acid zwitterion

[Term]
id: CHEBI:15722
name: peptidyl amide
def: "A peptide that has a carbamoyl group at the <em>C</em>-terminus." []
is_a: CHEBI:16670 ! peptide
relationship: RO:0018033 CHEBI:136962 ! is deprotonated form of peptidylamide(1+)

[Term]
id: CHEBI:15724
name: trimethylamine N-oxide
def: "A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134363 ! tertiary amine oxide
relationship: RO:0000087 CHEBI:25728 ! has role osmolyte
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:166856 ! is deprotonated form of hydroxytrimethylaminium
relationship: RO:0018038 CHEBI:18139 ! has functional parent trimethylamine

[Term]
id: CHEBI:15729
name: L-ornithine
def: "An optically active form of ornithine having <small>L</small>-configuration." []
synonym: "L-Ornithine" EXACT [KEGG_COMPOUND]
synonym: "L-ornithine" EXACT [ChEBI]
is_a: CHEBI:18257 ! ornithine
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:46911 ! is deprotonated form of L-ornithinium(1+)
relationship: RO:0018034 CHEBI:46914 ! is protonated form of L-ornithinate
relationship: RO:0018039 CHEBI:16176 ! is enantiomer of D-ornithine

[Term]
id: CHEBI:15733
name: N-methylaniline
def: "A methylaniline that is  aniline carrying a methyl substituent at the nitrogen atom." []
is_a: CHEBI:25275 ! methylaniline
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:60977 ! phenylalkylamine
relationship: RO:0018038 CHEBI:17296 ! has functional parent aniline

[Term]
id: CHEBI:15734
name: primary alcohol
def: "A primary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." []
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:15738
name: staurosporine
is_a: CHEBI:37697 ! indolocarbazole alkaloid
is_a: CHEBI:38165 ! organic heterooctacyclic compound
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:37700 ! has role EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:57491 ! is deprotonated form of staurosporinium

[Term]
id: CHEBI:15739
name: isopropylamine
def: "A member of the class of  alkylamines that is propane carrying an amino group at position 2." []
is_a: CHEBI:17062 ! primary aliphatic amine
is_a: CHEBI:22331 ! alkylamines
relationship: RO:0018033 CHEBI:57492 ! is deprotonated form of isopropylaminium

[Term]
id: CHEBI:15740
name: formate
def: "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30751 ! is deprotonated form of formic acid

[Term]
id: CHEBI:15741
name: succinic acid
def: "An α,ω-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle." []
synonym: "SUCCINIC ACID" EXACT [PDBeChem]
synonym: "Succinic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:28383 ! alpha,omega-dicarboxylic acid
is_a: CHEBI:66873 ! C4-dicarboxylic acid
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:66987 ! has role radiation protective agent
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:30779 ! is protonated form of succinate(1-)

[Term]
id: CHEBI:15743
name: butanal
def: "A member of the class of  butanals that consists of propane bearing a formyl substituent at the 1-position. The parent of the class of butanals." []
synonym: "Butanal" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22939 ! butanals
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:15746
name: spermine
def: "A polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism." []
is_a: CHEBI:39166 ! tetramine
is_a: CHEBI:39474 ! polyazaalkane
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:45725 ! is deprotonated form of spermine(4+)

[Term]
id: CHEBI:15756
name: hexadecanoic acid
def: "A straight-chain, sixteen-carbon, saturated long-chain fatty acid." []
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77119 ! has role EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:7896 ! is protonated form of hexadecanoate

[Term]
id: CHEBI:15765
name: L-dopa
def: "An optically active form of dopa having <small>L</small>-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease" []
synonym: "L-Dopa" EXACT [KEGG_COMPOUND]
is_a: CHEBI:27177 ! L-tyrosine derivative
is_a: CHEBI:49168 ! dopa
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
relationship: RO:0000087 CHEBI:35219 ! has role plant growth retardant
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:48560 ! has role dopaminergic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:59174 ! has role hapten
relationship: RO:0000087 CHEBI:62215 ! has role allelochemical
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:67012 ! is protonated form of L-dopa(1-)
relationship: RO:0018036 CHEBI:57504 ! is tautomer of L-dopa zwitterion
relationship: RO:0018039 CHEBI:49169 ! is enantiomer of D-dopa

[Term]
id: CHEBI:157668
name: carbocyclic fatty acid anion
def: "Any fatty acid anion containing a ring composed of carbon atoms. Major microspecies at pH 7.3" []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:35744 ! is deprotonated form of carbocyclic fatty acid

[Term]
id: CHEBI:15767
name: dichloromethane
def: "A member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine. A dense, non-flammible colourless liquid at room temperature (b.p. 40°C, d = 1.33) which is immiscible with water, it is widely used as a solvent, a paint stripper, and for the removal of caffeine from coffee and tea." []
synonym: "Dichloromethane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23148 ! chloromethanes
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:157671
name: AN11736
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38278 ! organoboron compound
is_a: CHEBI:84129 ! L-valine derivative

[Term]
id: CHEBI:157693
name: 3-(3,4-substituted-phenyl)-1,1-dimethylurea
def: "A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a phenyl group which carries two unspecified groups at positions 3 and 4 of the phenyl ring." []
is_a: CHEBI:134043 ! phenylureas

[Term]
id: CHEBI:15773
name: cyclohexylamine
def: "A primary aliphatic amine consisting of cyclohexane carrying an amino substituent." []
synonym: "Cyclohexanamine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:17062 ! primary aliphatic amine
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:42939 ! is deprotonated form of cyclohexylammonium

[Term]
id: CHEBI:157770
name: short-chain primary fatty alcohol
def: "Any primary fatty alcohol with a chain length less than 6 carbons." []
is_a: CHEBI:142622 ! primary fatty alcohol

[Term]
id: CHEBI:157775
name: N-acyl-beta-D-galactosylphytosphingosine
is_a: CHEBI:143593 ! beta-galactosylceramide

[Term]
id: CHEBI:15778
name: N-acyl-D-amino acid
def: "Any <em>N</em>-acyl-amino acid in which the amino acid moiety has <small>D</small> configuration." []
is_a: CHEBI:51569 ! N-acyl-amino acid
is_a: CHEBI:83812 ! non-proteinogenic amino acid derivative
relationship: RO:0018034 CHEBI:59876 ! is protonated form of N-acyl-D-alpha-amino acid anion
relationship: RO:0018039 CHEBI:21644 ! is enantiomer of N-acyl-L-amino acid

[Term]
id: CHEBI:15792
name: malonate(2-)
def: "A dicarboxylic acid dianion obtained by the deprotonation of the carboxy groups of malonic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133291 ! saturated dicarboxylic acid dianion(2-)
relationship: RO:0000087 CHEBI:25355 ! has role mitochondrial respiratory-chain inhibitor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30795 ! is deprotonated form of malonate(1-)

[Term]
id: CHEBI:15816
name: D-arginine
def: "A <small>D</small>-α-amino acid that is the <small>D</small>-isomer of arginine." []
synonym: "D-Arginine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:29016 ! arginine
relationship: RO:0000087 CHEBI:65053 ! has role EC 4.1.1.19 (arginine decarboxylase) inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:32689 ! is deprotonated form of D-argininium(1+)
relationship: RO:0018034 CHEBI:32688 ! is protonated form of D-argininate
relationship: RO:0018039 CHEBI:16467 ! is enantiomer of L-arginine

[Term]
id: CHEBI:15837
name: isoamylol
def: "An primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:50584 ! alkyl alcohol
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76206 ! has role xenobiotic metabolite
relationship: RO:0018040 CHEBI:30362 ! has parent hydride isopentane

[Term]
id: CHEBI:15841
name: polypeptide
def: "A peptide containing ten or more amino acid residues." []
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:15843
name: arachidonic acid
def: "A long-chain fatty acid that is a C<small><sub>20</sub></small>, polyunsaturated fatty acid having four (<i>Z</i>)-double bonds at positions 5, 8, 11 and 14." []
is_a: CHEBI:36009 ! omega-6 fatty acid
is_a: CHEBI:36306 ! icosa-5,8,11,14-tetraenoic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:78444 ! has role EC 3.1.1.1 (carboxylesterase) inhibitor
relationship: RO:0000087 CHEBI:83038 ! has role Daphnia galeata metabolite
relationship: RO:0018034 CHEBI:32395 ! is protonated form of arachidonate
relationship: RO:0018040 CHEBI:37834 ! has parent hydride (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraene

[Term]
id: CHEBI:15858
name: bromide
synonym: "Bromide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16042 ! halide anion
is_a: CHEBI:36896 ! monoatomic bromine
relationship: RO:0018033 CHEBI:47266 ! is deprotonated form of hydrogen bromide

[Term]
id: CHEBI:15862
name: ethylamine
def: "A two-carbon primary aliphatic amine." []
synonym: "ETHANAMINE" EXACT [PDBeChem]
is_a: CHEBI:17062 ! primary aliphatic amine
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:566789 ! is deprotonated form of ethylaminium

[Term]
id: CHEBI:15866
name: 2-deoxy-D-glucose
def: "A deoxyglucose that is <small>D</small>-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent." []
synonym: "2-Deoxy-D-arabino-hexose" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23623 ! deoxyglucose
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0018038 CHEBI:4167 ! has functional parent D-glucopyranose

[Term]
id: CHEBI:15882
name: phenol
def: "An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols." []
synonym: "PHENOL" EXACT [PDBeChem]
synonym: "Phenol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:64952 ! has role anti-HSV agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:50526 ! is protonated form of phenolate

[Term]
id: CHEBI:15889
name: sterol
def: "Any 3-hydroxy steroid whose skeleton is closely related to cholestan-3-ol (additional carbon atoms may be present in the side chain)." []
is_a: CHEBI:36834 ! 3-hydroxy steroid

[Term]
id: CHEBI:15891
name: taurine
def: "An amino sulfonic acid that is the 2-amino derivative of ethanesulfonic acid. It is a naturally occurring amino acid derived from  methionine and cysteine metabolism. An abundant component of fish- and meat-based foods, it has been used as an oral supplement in the treatment of disorders such as cystic fibrosis and hypertension." []
synonym: "2-Aminoethanesulfonic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:37793 ! amino sulfonic acid
relationship: RO:0000087 CHEBI:33284 ! has role nutrient
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:64589 ! has role glycine receptor agonist
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:32970 ! is protonated form of 2-aminoethanesulfonate
relationship: RO:0018036 CHEBI:507393 ! is tautomer of taurine zwitterion

[Term]
id: CHEBI:15903
name: beta-D-glucose
def: "<small>D</small>-Glucopyranose with β configuration at the anomeric centre." []
is_a: CHEBI:4167 ! D-glucopyranose
relationship: RO:0000087 CHEBI:53000 ! has role epitope
relationship: RO:0018039 CHEBI:37631 ! is enantiomer of beta-L-glucose

[Term]
id: CHEBI:15904
name: long-chain fatty acid
def: "A fatty acid with a chain length ranging from C<small><sub>13</sub></small> to C<small><sub>22</sub></small>." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:57560 ! is protonated form of long-chain fatty acid anion

[Term]
id: CHEBI:15929
name: (-)-methyl jasmonate
def: "A jasmonate ester that is the methyl ester of jasmonic acid." []
is_a: CHEBI:167055 ! Jasmonate derivatives
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:52464 ! jasmonate ester
relationship: RO:0000087 CHEBI:24937 ! has role jasmonates
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:15930
name: atrazine
def: "A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6 while one of hydrogens of each amino group is replaced respectively by an ethyl and a propan-2-yl group." []
is_a: CHEBI:38168 ! chloro-1,3,5-triazine
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:27726 ! has functional parent 6-chloro-1,3,5-triazine-2,4-diamine

[Term]
id: CHEBI:15939
name: glycyrrhizinic acid
def: "A  triterpenoid saponin that is the  glucosiduronide derivative of 3β-hydroxy-11-oxoolean-12-en-30-oic acid." []
is_a: CHEBI:24302 ! glucosiduronic acid
is_a: CHEBI:25872 ! pentacyclic triterpenoid
is_a: CHEBI:27093 ! tricarboxylic acid
is_a: CHEBI:35381 ! monosaccharide
is_a: CHEBI:51689 ! enone
is_a: CHEBI:61778 ! triterpenoid saponin
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:65232 ! has role EC 3.4.21.5 (thrombin) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:29807 ! is protonated form of glycyrrhizinate(3-)

[Term]
id: CHEBI:15940
name: nicotinic acid
def: "A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group." []
synonym: "NICOTINIC ACID" EXACT [PDBeChem]
synonym: "Nicotinic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:176839 ! vitamin B3
is_a: CHEBI:26416 ! pyridine alkaloid
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0000087 CHEBI:84264 ! has role EC 3.5.1.19 (nicotinamidase) inhibitor
relationship: RO:0018034 CHEBI:32544 ! is protonated form of nicotinate

[Term]
id: CHEBI:15948
name: lycopene
def: "An acyclic carotene commonly obtained from tomatoes and other red fruits." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23044 ! carotenoid
is_a: CHEBI:35162 ! acyclic carotene
relationship: BFO:0000051 CHEBI:139114 ! has part carotenoid psi-end derivative
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:15956
name: biotin
def: "An organic heterobicyclic compound that consists of 2-oxohexahydro-1<em>H</em>-thieno[3,4-<em>d</em>]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins." []
is_a: CHEBI:176841 ! vitamin B7
is_a: CHEBI:51570 ! biotins
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:23354 ! has role coenzyme
relationship: RO:0000087 CHEBI:26348 ! has role prosthetic group
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:57586 ! is protonated form of biotinate

[Term]
id: CHEBI:15964
name: cyclohexylsulfamic acid
def: "A member of the class of sulfamic acids that is sulfamic acid  carrying an <em>N</em>-cyclohexyl substituent." []
synonym: "Cyclohexylsulfamate" EXACT [KEGG_COMPOUND]
synonym: "Cyclohexylsulfamic acid" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35719 ! sulfamic acids
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:57592 ! is protonated form of cyclohexylsulfamate
relationship: RO:0018038 CHEBI:9330 ! has functional parent sulfamic acid

[Term]
id: CHEBI:15966
name: D-glutamic acid
def: "An optically active form of glutamic acid having <small>D</small>-configuration." []
synonym: "D-Glutamic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:18237 ! glutamic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:29986 ! is protonated form of D-glutamate(1-)
relationship: RO:0018039 CHEBI:16015 ! is enantiomer of L-glutamic acid

[Term]
id: CHEBI:15986
name: polynucleotide
def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." []
is_a: CHEBI:33695 ! information biomacromolecule
is_a: CHEBI:61120 ! nucleobase-containing molecular entity
relationship: BFO:0000051 CHEBI:50319 ! has part nucleotide residue

[Term]
id: CHEBI:16000
name: ethanolamine
def: "A member of the class of  ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:32877 ! primary amine
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:57603 ! is deprotonated form of ethanolaminium(1+)

[Term]
id: CHEBI:16004
name: (R)-lactate
def: "An optically active form of lactate having (<i>R</i>)-configuration." []
is_a: CHEBI:24996 ! lactate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:42111 ! is deprotonated form of (R)-lactic acid
relationship: RO:0018039 CHEBI:16651 ! is enantiomer of (S)-lactate

[Term]
id: CHEBI:16005
name: methylarsonate(2-)
is_a: CHEBI:50956 ! organoarsonic acid anion
relationship: RO:0018033 CHEBI:33409 ! is deprotonated form of methylarsonate(1-)

[Term]
id: CHEBI:16007
name: methanethiol
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47908 ! alkanethiol
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:16010
name: 5-oxoproline
def: "An oxoproline having the oxo group placed at the 5-position. It is an intermediate metabolite in the glutathione cycle." []
synonym: "5-OXOPROLINE" EXACT [PDBeChem]
synonym: "5-Oxoproline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25801 ! oxoproline
is_a: CHEBI:74223 ! pyrrolidin-2-ones
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:57606 ! is protonated form of 5-oxoprolinate

[Term]
id: CHEBI:16015
name: L-glutamic acid
def: "An optically active form of glutamic acid having <small>L</small>-configuration." []
synonym: "GLUTAMIC ACID" EXACT [PDBeChem]
synonym: "L-Glutamic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:18237 ! glutamic acid
is_a: CHEBI:24318 ! glutamine family amino acid
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:29985 ! is protonated form of L-glutamate(1-)
relationship: RO:0018039 CHEBI:15966 ! is enantiomer of D-glutamic acid

[Term]
id: CHEBI:160246
name: aminophenazone
def: "A  pyrazolone  that is 1,2-dihydro-3<em>H</em>-pyrazol-3-one substituted by a dimethylamino group at position 4, methyl groups at positions 1 and 5 and a phenyl group at position 2. It exhibits analgesic, anti-inflammatory, and antipyretic properties." []
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:83328 ! pyrazolone
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:16037
name: 2-nitropropane
def: "A secondary nitroalkane that is propane in which a hydrogen at position 2 has been replaced by a nitro group. Mainly used as a solvent (b.p. 120°C)." []
synonym: "2-Nitropropane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:139218 ! secondary nitroalkane
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent

[Term]
id: CHEBI:16040
name: cytosine
def: "An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4." []
is_a: CHEBI:26432 ! pyrimidine nucleobase
is_a: CHEBI:38337 ! pyrimidone
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:38387 ! 9,11,15-octadecatrienoic acid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:16042
name: halide anion
def: "A monoatomic monoanion resulting from the addition of an electron to any halogen atom." []
is_a: CHEBI:33429 ! monoatomic monoanion
is_a: CHEBI:79389 ! monovalent inorganic anion

[Term]
id: CHEBI:16052
name: propene
def: "An alkene that is propane with a double bond at position 1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:32878 ! alkene
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:1606
name: 1-methyl-4-imidazoleacetic acid
def: "A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1-methyl-1<em>H</em>-imidazol-4-yl group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:38307 ! imidazolyl carboxylic acid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:51373 ! has role GABA agonist
relationship: RO:0018034 CHEBI:132918 ! is protonated form of 1-methyl-4-imidazoleacetate
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:16066
name: 11-cis-retinal
def: "A retinal having 2<i>E</i>,4<i>Z</i>,6<i>E</i>,8<i>E</i>-double bond geometry." []
synonym: "11-cis-Retinal" EXACT [KEGG_COMPOUND]
synonym: "11-cis-retinal" EXACT [ChEBI]
is_a: CHEBI:15035 ! retinal
relationship: RO:0000087 CHEBI:23240 ! has role chromophore
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:16072
name: maleimide
def: "A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1<em>H</em>-pyrrole-2,5-dione structure." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:55417 ! maleimides
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0018040 CHEBI:19203 ! has parent hydride 1H-pyrrole

[Term]
id: CHEBI:16080
name: gamma-amino-beta-hydroxybutyric acid
def: "A γ-amino acid comprising 4-aminobutyric acid having a 2-hydroxy substituent." []
synonym: "4-Amino-3-hydroxybutanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33707 ! gamma-amino acid
is_a: CHEBI:35969 ! 3-hydroxy monocarboxylic acid
is_a: CHEBI:60911 ! racemate
relationship: RO:0018034 CHEBI:11955 ! is protonated form of 4-amino-3-hydroxybutanoate
relationship: RO:0018036 CHEBI:57630 ! is tautomer of gamma-amino-beta-hydroxybutyric acid zwitterion
relationship: RO:0018038 CHEBI:30772 ! has functional parent butyric acid

[Term]
id: CHEBI:16101
name: ethylbenzene
def: "An  alkylbenzene carrying an ethyl substituent. It is a constituent of coal tar and petroleum." []
synonym: "Ethylbenzene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38976 ! alkylbenzene
relationship: RO:0000087 CHEBI:747333 ! has role plastic filler

[Term]
id: CHEBI:16112
name: chlorogenic acid
def: "A cinnamate ester obtained by formal condensation of the carboxy group of <em>trans</em>-caffeic acid with the 3-hydroxy group of quinic acid. It is an intermediate metabolite in the biosynthesis of lignin." []
is_a: CHEBI:26493 ! quinic acid
is_a: CHEBI:26848 ! tannin
is_a: CHEBI:36087 ! cinnamate ester
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:78295 ! has role food component
relationship: RO:0018034 CHEBI:57644 ! is protonated form of chlorogenate
relationship: RO:0018038 CHEBI:16433 ! has functional parent trans-caffeic acid
relationship: RO:0018038 CHEBI:17521 ! has functional parent (-)-quinic acid

[Term]
id: CHEBI:16113
name: cholesterol
def: "A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3β-hydroxy group." []
synonym: "Cholest-5-en-3beta-ol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131619 ! C27-steroid
is_a: CHEBI:1722 ! 3beta-hydroxy-Delta(5)-steroid
is_a: CHEBI:35348 ! 3beta-sterol
is_a: CHEBI:50401 ! cholestanoid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83038 ! has role Daphnia galeata metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite

[Term]
id: CHEBI:16118
name: berberine
is_a: CHEBI:22754 ! berberine alkaloid
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:86322 ! alkaloid antibiotic
is_a: CHEBI:86494 ! botanical anti-fungal agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35608 ! has role EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:48550 ! has role EC 1.1.1.21 (aldehyde reductase) inhibitor
relationship: RO:0000087 CHEBI:50469 ! has role EC 3.1.1.4 (phospholipase A2) inhibitor
relationship: RO:0000087 CHEBI:50509 ! has role potassium channel blocker
relationship: RO:0000087 CHEBI:68612 ! has role EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor
relationship: RO:0000087 CHEBI:72854 ! has role EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0000087 CHEBI:77108 ! has role EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor
relationship: RO:0000087 CHEBI:77110 ! has role EC 1.21.3.3 (reticuline oxidase) inhibitor
relationship: RO:0000087 CHEBI:77111 ! has role EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor
relationship: RO:0000087 CHEBI:77113 ! has role EC 2.7.11.10 (IkappaB kinase) inhibitor
relationship: RO:0000087 CHEBI:77115 ! has role EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor

[Term]
id: CHEBI:16130
name: DDT
def: "A chlorophenylethane that is 1,1,1-trichloro-2,2-diphenylethane substituted by additional chloro substituents at positions 4 of the phenyl substituents. It is a commonly used organochlorine insecticide." []
is_a: CHEBI:23154 ! chlorophenylethane
is_a: CHEBI:25705 ! organochlorine insecticide
is_a: CHEBI:51614 ! diarylmethane
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:138015 ! has role endocrine disruptor
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:39412 ! has role bridged diphenyl acaricide
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0018038 CHEBI:28763 ! has functional parent 4,4'-dichlorodiphenylmethane
relationship: RO:0018038 CHEBI:39161 ! has functional parent 1,1,1-trichloro-2,2-diphenylethane

[Term]
id: CHEBI:16134
name: ammonia
def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." []
synonym: "AMMONIA" EXACT [PDBeChem]
synonym: "Ammonia" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:35107 ! azane
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:59740 ! has role nucleophilic reagent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant
relationship: RO:0018033 CHEBI:28938 ! is deprotonated form of ammonium
relationship: RO:0018034 CHEBI:29337 ! is protonated form of azanide

[Term]
id: CHEBI:16136
name: hydrogen sulfide
def: "A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen." []
synonym: "Hydrogen sulfide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:33405 ! hydracid
is_a: CHEBI:33535 ! sulfur hydride
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:30488 ! is deprotonated form of sulfonium
relationship: RO:0018034 CHEBI:29919 ! is protonated form of hydrosulfide

[Term]
id: CHEBI:16150
name: benzoate
def: "The simplest member of the class of  benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22718 ! benzoates
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:30746 ! is deprotonated form of benzoic acid

[Term]
id: CHEBI:16158
name: steroid sulfate
def: "A sulfuric ester obtained by the formal condensation of a hydroxy group of any steroid with sulfuric acid." []
is_a: CHEBI:25704 ! organic sulfate
is_a: CHEBI:26819 ! sulfuric ester
is_a: CHEBI:47880 ! steroid ester

[Term]
id: CHEBI:16162
name: o-orsellinate
def: "A dihydroxybenzoate that is the  conjugate base of <em>o</em>-orsellinic acid." []
is_a: CHEBI:36084 ! dihydroxybenzoate
relationship: RO:0018033 CHEBI:32807 ! is deprotonated form of o-orsellinic acid

[Term]
id: CHEBI:16170
name: mercury(0)
def: "Elemental mercury of oxidation state zero." []
synonym: "Mercury" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35113 ! elemental mercury
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:16176
name: D-ornithine
def: "The <small>D</small>-enantiomer of ornithine. It is an intermediate metabolite produced in the urea cycle." []
synonym: "D-Ornithine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:18257 ! ornithine
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:57668 ! is deprotonated form of D-ornithinium(1+)
relationship: RO:0018039 CHEBI:15729 ! is enantiomer of L-ornithine

[Term]
id: CHEBI:16180
name: N-acylglycine
def: "An <em>N</em>-acyl-amino acid in which amino acid specified is glycine." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:24373 ! glycine derivative
is_a: CHEBI:51569 ! N-acyl-amino acid
relationship: RO:0018034 CHEBI:57670 ! is protonated form of N-acylglycinate

[Term]
id: CHEBI:16183
name: methane
def: "A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. −161°C)." []
synonym: "Methane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18310 ! alkane
is_a: CHEBI:37176 ! mononuclear parent hydride
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:35230 ! has role fossil fuel
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018034 CHEBI:29438 ! is protonated form of methanide

[Term]
id: CHEBI:16189
name: sulfate
def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." []
synonym: "Sulfate" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33482 ! sulfur oxoanion
is_a: CHEBI:48154 ! sulfur oxide
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:45696 ! is deprotonated form of hydrogensulfate

[Term]
id: CHEBI:16196
name: oleic acid
def: "An octadec-9-enoic acid in which the double bond at C-9 has <i>Z</i> (<i>cis</i>) stereochemistry." []
synonym: "Octadec-9-enoic acid" EXACT [ChEMBL]
is_a: CHEBI:36021 ! octadec-9-enoic acid
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:78444 ! has role EC 3.1.1.1 (carboxylesterase) inhibitor
relationship: RO:0000087 CHEBI:83038 ! has role Daphnia galeata metabolite
relationship: RO:0018034 CHEBI:30823 ! is protonated form of oleate
relationship: RO:0018040 CHEBI:37604 ! has parent hydride cis-octadec-9-ene

[Term]
id: CHEBI:16199
name: urea
def: "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." []
synonym: "UREA" EXACT [PDBeChem]
synonym: "Urea" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:64577 ! has role flour treatment agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018036 CHEBI:48376 ! is tautomer of carbamimidic acid
relationship: RO:0018038 CHEBI:28976 ! has functional parent carbonic acid

[Term]
id: CHEBI:16215
name: phosphonate(2-)
def: "A divalent inorganic anion obtained by removal of both protons from phosphonic acid" []
is_a: CHEBI:33461 ! phosphorus oxoanion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:33462 ! is deprotonated form of phosphonate(1-)

[Term]
id: CHEBI:16223
name: dimethylarsinate
def: "The arsenic oxoanion that is the conjugate base of dimethylarsinic acid." []
synonym: "Dimethylarsinate" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35776 ! arsenic oxoanion
relationship: RO:0018033 CHEBI:48765 ! is deprotonated form of dimethylarsinic acid
relationship: RO:0018038 CHEBI:29846 ! has functional parent arsinate

[Term]
id: CHEBI:16227
name: pyridine
def: "An  azaarene comprising a benzene core in which one -CH group is replaced by a nitrogen atom. It is the parent compound of the class pyridines." []
synonym: "Pyridine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35555 ! mancude organic heteromonocyclic parent
is_a: CHEBI:38179 ! monocyclic heteroarene
is_a: CHEBI:50893 ! azaarene
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:16234
name: hydroxide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33693 ! oxygen hydride
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:15377 ! is deprotonated form of water

[Term]
id: CHEBI:16235
name: guanine
def: "A 2-aminopurine carrying a 6-oxo substituent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:20702 ! 2-aminopurines
is_a: CHEBI:25810 ! oxopurine
is_a: CHEBI:26386 ! purine nucleobase
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018040 CHEBI:35589 ! has parent hydride 9H-purine

[Term]
id: CHEBI:16236
name: ethanol
def: "A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group." []
synonym: "ETHANOL" EXACT [PDBeChem]
synonym: "Ethanol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:23982 ! ethanols
is_a: CHEBI:50584 ! alkyl alcohol
relationship: RO:0000087 CHEBI:35488 ! has role central nervous system depressant
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:48354 ! has role polar solvent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:64018 ! has role protein kinase C agonist
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:52092 ! is protonated form of ethoxide

[Term]
id: CHEBI:16240
name: hydrogen peroxide
def: "An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond." []
synonym: "HYDROGEN PEROXIDE" EXACT [PDBeChem]
synonym: "Hydrogen peroxide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24837 ! inorganic peroxide
is_a: CHEBI:26523 ! reactive oxygen species
relationship: RO:0000087 CHEBI:132717 ! has role bleaching agent
relationship: RO:0000087 CHEBI:149552 ! has role emetic
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:63490 ! has role explosive
relationship: RO:0000087 CHEBI:65259 ! has role GABA antagonist
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:29192 ! is protonated form of hydrogenperoxide(1-)

[Term]
id: CHEBI:16243
name: quercetin
def: "A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25883 ! pentahydroxyflavone
is_a: CHEBI:52267 ! 7-hydroxyflavonol
is_a: CHEBI:72010 ! hydroxyflavan
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38161 ! has role chelator
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:70770 ! has role Aurora kinase inhibitor
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76989 ! has role phytoestrogen
relationship: RO:0000087 CHEBI:77020 ! has role EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor
relationship: RO:0018034 CHEBI:57694 ! is protonated form of quercetin-7-olate

[Term]
id: CHEBI:16247
name: phospholipid
def: "A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:37734 ! phosphoric ester
relationship: RO:0018034 CHEBI:62643 ! is protonated form of anionic phospholipid

[Term]
id: CHEBI:16260
name: 2-nitrophenol
def: "A member of the class of 2-nitrophenols that is phenol in which one of the hydrogens that is <em>ortho</em> to the hydroxy group has been replaced by a nitro group." []
synonym: "2-Nitrophenol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:86421 ! 2-nitrophenols
relationship: RO:0018034 CHEBI:57703 ! is protonated form of 2-nitrophenolate

[Term]
id: CHEBI:16261
name: chitosan
def: "An aminoglycan consisting of β-(1→4)-linked <small>D</small>-glucosamine residues." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22506 ! aminoglycan
is_a: CHEBI:72813 ! exopolysaccharide
relationship: RO:0000087 CHEBI:192504 ! has role elicitor
relationship: RO:0000087 CHEBI:73182 ! has role plant activator
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:57704 ! is deprotonated form of cationic chitosan

[Term]
id: CHEBI:16268
name: nitroethane
def: "A nitroalkane that is ethane substituted by a nitro group." []
synonym: "Nitroethane" EXACT [KEGG_COMPOUND]
synonym: "nitroethane" EXACT [UniProt]
is_a: CHEBI:133972 ! primary nitroalkane
relationship: RO:0018036 CHEBI:77894 ! is tautomer of aci-nitroethane

[Term]
id: CHEBI:16269
name: N,N-dimethylaniline
def: "A tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups." []
is_a: CHEBI:23806 ! dimethylaniline
is_a: CHEBI:32876 ! tertiary amine

[Term]
id: CHEBI:16277
name: haloacetic acid
def: "A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a halogen atom." []
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0018034 CHEBI:85638 ! is protonated form of haloacetate(1-)
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:16301
name: nitrite
def: "The nitrogen oxoanion formed by loss of a proton from nitrous acid." []
synonym: "Nitrite" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33458 ! nitrogen oxoanion
is_a: CHEBI:62764 ! reactive nitrogen species
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:25567 ! is deprotonated form of nitrous acid

[Term]
id: CHEBI:16313
name: D-proline
def: "The <small>D</small>-enantiomer of proline." []
synonym: "D-Proline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:26271 ! proline
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:32868 ! is deprotonated form of D-prolinium
relationship: RO:0018034 CHEBI:32867 ! is protonated form of D-prolinate
relationship: RO:0018036 CHEBI:57726 ! is tautomer of D-proline zwitterion
relationship: RO:0018039 CHEBI:17203 ! is enantiomer of L-proline

[Term]
id: CHEBI:16330
name: 17beta-hydroxy-5alpha-androstan-3-one
def: "A 17β-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with α-configuration at position 5." []
synonym: "17beta-Hydroxy-5alpha-androstan-3-one" EXACT [KEGG_COMPOUND]
synonym: "17beta-hydroxy-5alpha-androstan-3-one" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13601 ! 3-oxo-5alpha-steroid
is_a: CHEBI:36834 ! 3-hydroxy steroid
is_a: CHEBI:85278 ! 17beta-hydroxyandrostan-3-one
relationship: RO:0000087 CHEBI:50113 ! has role androgen
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018040 CHEBI:28859 ! has parent hydride 5alpha-androstane

[Term]
id: CHEBI:16333
name: 2-arylpropionic acid
def: "A class of carboxylic acids of general formula RCHCH3C(=O)OH where R represents an aryl group." []
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0018034 CHEBI:57738 ! is protonated form of 2-arylpropionate
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:16335
name: adenosine
def: "A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a β‒N<small><sup>9</small></sup>-glycosidic bond." []
synonym: "ADENOSINE" EXACT [PDBeChem]
synonym: "Adenosine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:142355 ! purines D-ribonucleoside
is_a: CHEBI:22260 ! adenosines
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:16336
name: hyaluronic acid
def: "A mucopolysaccharide composed of <em>N</em>-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37395 ! mucopolysaccharide
is_a: CHEBI:72813 ! exopolysaccharide
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:132153 ! is protonated form of hyaluronate

[Term]
id: CHEBI:16344
name: guanidinoacetic acid
def: "The <em>N</em>-amidino derivative of glycine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24439 ! guanidinoacetic acids
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:86264 ! has role rat metabolite
relationship: RO:0018034 CHEBI:131444 ! is protonated form of guanidinoacetate
relationship: RO:0018036 CHEBI:57742 ! is tautomer of guanidinoacetic acid zwitterion

[Term]
id: CHEBI:16349
name: L-citrulline
def: "The <small>L</small>-enantiomer of citrulline." []
synonym: "CITRULLINE" EXACT [PDBeChem]
synonym: "L-Citrulline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:18211 ! citrulline
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:61908 ! has role EC 1.14.13.39 (nitric oxide synthase) inhibitor
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018036 CHEBI:57743 ! is tautomer of L-citrulline zwitterion
relationship: RO:0018039 CHEBI:49007 ! is enantiomer of D-citrulline

[Term]
id: CHEBI:16356
name: 3',5'-cyclic GMP
def: "A 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19834 ! 3',5'-cyclic purine nucleotide
is_a: CHEBI:61295 ! guanyl ribonucleotide
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:57746 ! is protonated form of 3',5'-cyclic GMP(1-)

[Term]
id: CHEBI:16359
name: cholic acid
def: "A bile acid that is 5β-cholan-24-oic acid bearing three α-hydroxy substituents at position 3, 7 and 12." []
is_a: CHEBI:131620 ! C24-steroid
is_a: CHEBI:27114 ! trihydroxy-5beta-cholanic acid
is_a: CHEBI:3098 ! bile acid
is_a: CHEBI:36835 ! 3alpha-hydroxy steroid
is_a: CHEBI:36843 ! 7alpha-hydroxy steroid
is_a: CHEBI:36846 ! 12alpha-hydroxy steroid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:29747 ! is protonated form of cholate

[Term]
id: CHEBI:16366
name: anthocyanidin cation
def: "Any organic cation that is an aglycon of anthocyanin cation; they are oxygenated derivatives of flavylium (2-phenylchromenylium)." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:47916 ! flavonoid
relationship: RO:0018038 CHEBI:36121 ! has functional parent flavylium

[Term]
id: CHEBI:16374
name: menaquinone
def: "Any member of the class of menaquinones that is 2-methyl-1,4-naphthoquinone with an unsaturated isoprenoid chain at the 3-position." []
is_a: CHEBI:25185 ! menaquinones
is_a: CHEBI:28384 ! vitamin K
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:16375
name: D-cysteine
def: "An optically active form of cysteine having <small>D</small>-configuration." []
synonym: "D-CYSTEINE" EXACT [PDBeChem]
synonym: "D-Cysteine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:15356 ! cysteine
is_a: CHEBI:16733 ! D-alpha-amino acid
relationship: RO:0018033 CHEBI:32451 ! is deprotonated form of D-cysteinium
relationship: RO:0018034 CHEBI:32449 ! is protonated form of D-cysteinate(1-)
relationship: RO:0018036 CHEBI:35236 ! is tautomer of D-cysteine zwitterion
relationship: RO:0018039 CHEBI:17561 ! is enantiomer of L-cysteine

[Term]
id: CHEBI:16382
name: iodide
synonym: "Iodide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:16042 ! halide anion
is_a: CHEBI:36897 ! monoatomic iodine
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:43451 ! is deprotonated form of hydrogen iodide

[Term]
id: CHEBI:16385
name: organic sulfide
def: "Compounds having the structure RSR (R ≠ H). Such compounds were once called thioethers." []
is_a: CHEBI:26822 ! sulfide
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:16389
name: ubiquinones
def: "Any benzoquinone derived from 2,3-dimethoxy-5-methylbenzoquinone; one of a group of naturally occurring homologues. The redox-active quinoid moiety usually carries a polyprenoid side chain at position 6, the number of isoprenoid units in which is species-specific. Ubiquinones are involved in the control of mitochondrial electron transport, and are also potent anti-oxidants." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132124 ! 1,4-benzoquinones
is_a: CHEBI:26255 ! prenylquinone
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018038 CHEBI:46691 ! has functional parent 2,3-dihydroxy-5-methyl-1,4-benzoquinone

[Term]
id: CHEBI:16393
name: sphingosine
def: "A sphing-4-enine in which the double bond is <i>trans</i>." []
is_a: CHEBI:26743 ! sphing-4-enine
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:57756 ! is deprotonated form of sphingosine(1+)
relationship: RO:0018039 CHEBI:46967 ! is enantiomer of L-erythro-sphingosine

[Term]
id: CHEBI:16397
name: formamide
def: "The simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes." []
synonym: "FORMAMIDE" EXACT [PDBeChem]
synonym: "Formamide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24079 ! formamides
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0018036 CHEBI:48431 ! is tautomer of formimidic acid
relationship: RO:0018038 CHEBI:30751 ! has functional parent formic acid

[Term]
id: CHEBI:16398
name: D-threonine
def: "An optically active form of threonine having <small>D</small>-configuration." []
synonym: "D-Threonine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:26986 ! threonine
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:32828 ! is deprotonated form of D-threoninium
relationship: RO:0018034 CHEBI:32827 ! is protonated form of D-threoninate
relationship: RO:0018036 CHEBI:57757 ! is tautomer of D-threonine zwitterion
relationship: RO:0018039 CHEBI:16857 ! is enantiomer of L-threonine

[Term]
id: CHEBI:16411
name: indole-3-acetic acid
def: "A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1<em>H</em>-indol-3-yl group." []
is_a: CHEBI:24803 ! indole-3-acetic acids
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0000087 CHEBI:22676 ! has role auxin
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:30854 ! is protonated form of indole-3-acetate

[Term]
id: CHEBI:16412
name: lipopolysaccharide
def: "Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria)." []
is_a: CHEBI:35740 ! liposaccharide
is_a: CHEBI:65212 ! polysaccharide derivative
relationship: BFO:0000051 CHEBI:64637 ! has part O-polysaccharide

[Term]
id: CHEBI:16414
name: L-valine
def: "The <small>L</small>-enantiomer of valine." []
synonym: "L-Valine" EXACT [KEGG_COMPOUND]
synonym: "VALINE" EXACT [PDBeChem]
is_a: CHEBI:26463 ! pyruvate family amino acid
is_a: CHEBI:27266 ! valine
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32852 ! is deprotonated form of L-valinium
relationship: RO:0018034 CHEBI:32851 ! is protonated form of L-valinate
relationship: RO:0018036 CHEBI:57762 ! is tautomer of L-valine zwitterion
relationship: RO:0018039 CHEBI:27477 ! is enantiomer of D-valine

[Term]
id: CHEBI:164200
name: triclosan
def: "An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:139512 ! has role EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50683 ! has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:16433
name: trans-caffeic acid
def: "The <i>trans</i>-isomer of caffeic acid." []
is_a: CHEBI:36281 ! caffeic acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:57770 ! is protonated form of trans-caffeate

[Term]
id: CHEBI:16449
name: alanine
def: "An α-amino acid that consists of propionic acid bearing an amino substituent at position 2." []
synonym: "2-Aminopropanoic acid" EXACT [KEGG_COMPOUND]
synonym: "Alanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33704 ! alpha-amino acid
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32440 ! is deprotonated form of alaninium
relationship: RO:0018034 CHEBI:32439 ! is protonated form of alaninate
relationship: RO:0018036 CHEBI:66916 ! is tautomer of alanine zwitterion
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:16454
name: pantothenate
def: "A monocarboxylic acid anion that is the conjugate base of pantothenic acid, obtained by deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:7916 ! is deprotonated form of pantothenic acid

[Term]
id: CHEBI:16464
name: salicyl alcohol
def: "A hydroxybenzyl alcohol that is phenol substituted by a hydroxymethyl group at C-2." []
synonym: "2-(Hydroxymethyl)phenol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24679 ! hydroxybenzyl alcohol
is_a: CHEBI:33857 ! aromatic primary alcohol
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018038 CHEBI:15882 ! has functional parent phenol
relationship: RO:0018038 CHEBI:17987 ! has functional parent benzyl alcohol

[Term]
id: CHEBI:16467
name: L-arginine
def: "An <small>L</small>-α-amino acid that is the <small>L</small>-isomer of arginine." []
synonym: "L-Arginine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24318 ! glutamine family amino acid
is_a: CHEBI:29016 ! arginine
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:32682 ! is deprotonated form of L-argininium(1+)
relationship: RO:0018034 CHEBI:32681 ! is protonated form of L-argininate
relationship: RO:0018039 CHEBI:15816 ! is enantiomer of D-arginine

[Term]
id: CHEBI:16469
name: 17beta-estradiol
def: "The 17β-isomer of estradiol." []
is_a: CHEBI:23965 ! estradiol
is_a: CHEBI:35343 ! 17beta-hydroxy steroid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:62872 ! has role EC 1.2.3.1 (aldehyde oxidase) inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite

[Term]
id: CHEBI:16472
name: pentan-2-one
def: "A pentanone carrying an oxo substituent at position 2." []
synonym: "Pentan-2-one" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25892 ! pentanone
is_a: CHEBI:51867 ! methyl ketone
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:16480
name: nitric oxide
def: "A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35196 ! nitrogen oxide
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36871 ! inorganic radical
is_a: CHEBI:62764 ! reactive nitrogen species
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:16482
name: naphthalene
def: "An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia." []
synonym: "NAPHTHALENE" EXACT [PDBeChem]
synonym: "Naphthalene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:35426 ! ortho-fused bicyclic arene
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:16494
name: lipoic acid
def: "A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position." []
is_a: CHEBI:39192 ! dithiolanes
is_a: CHEBI:48847 ! heterocyclic fatty acid
is_a: CHEBI:59643 ! thia fatty acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:30313 ! is protonated form of lipoate
relationship: RO:0018038 CHEBI:28837 ! has functional parent octanoic acid

[Term]
id: CHEBI:16503
name: selane
synonym: "Hydrogen selenide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36903 ! selenium hydride
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:30485 ! is deprotonated form of selenonium
relationship: RO:0018034 CHEBI:29317 ! is protonated form of selanide

[Term]
id: CHEBI:16510
name: 3-hydroxypropionate
def: "A hydroxy monocarboxylic acid anion that is the conjugate base of 3-hydroxypropionic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:33404 ! is deprotonated form of 3-hydroxypropionic acid
relationship: RO:0018038 CHEBI:17272 ! has functional parent propionate

[Term]
id: CHEBI:16522
name: trans-zeatin
def: "The <i>trans</i>-isomer of zeatin." []
is_a: CHEBI:15333 ! zeatin
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:165223
name: Adriamycinone
is_a: CHEBI:36141 ! quinone
is_a: CHEBI:51270 ! tetracenes

[Term]
id: CHEBI:16523
name: D-serine
def: "The <i>R</i>-enantiomer of serine." []
synonym: "D-SERINE" EXACT [PDBeChem]
synonym: "D-Serine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:17822 ! serine
is_a: CHEBI:26649 ! serine derivative
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:64571 ! has role NMDA receptor agonist
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32841 ! is deprotonated form of D-serinium
relationship: RO:0018034 CHEBI:32840 ! is protonated form of D-serinate
relationship: RO:0018036 CHEBI:35247 ! is tautomer of D-serine zwitterion
relationship: RO:0018039 CHEBI:17115 ! is enantiomer of L-serine

[Term]
id: CHEBI:16525
name: taurochenodeoxycholic acid
def: "A bile acid taurine conjugate of  chenodeoxycholic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23219 ! bile acid taurine conjugate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:9407 ! is protonated form of taurochenodeoxycholate
relationship: RO:0018038 CHEBI:16755 ! has functional parent chenodeoxycholic acid

[Term]
id: CHEBI:16526
name: carbon dioxide
def: "A one-carbon compound with formula CO<small><sub>2</sub></small> in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food." []
synonym: "CARBON DIOXIDE" EXACT [PDBeChem]
synonym: "Carbon dioxide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:23014 ! carbon oxide
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38867 ! has role anaesthetic
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:48706 ! has role antagonist
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas
relationship: RO:0000087 CHEBI:78017 ! has role food propellant
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:16541
name: protein polypeptide chain
def: "A naturally occurring polypeptide synthesized at the ribosome." []
is_a: CHEBI:15841 ! polypeptide
relationship: BFO:0000051 CHEBI:33700 ! has part proteinogenic amino-acid residue

[Term]
id: CHEBI:16547
name: coniferyl aldehyde
def: "A member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134251 ! guaiacols
is_a: CHEBI:23245 ! cinnamaldehydes
is_a: CHEBI:26004 ! phenylpropanoid
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018038 CHEBI:16731 ! has functional parent (E)-cinnamaldehyde

[Term]
id: CHEBI:16548
name: chlordecone
def: "An  organochlorine compound with insecticidal activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:3992 ! cyclic ketone
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:16551
name: alpha,alpha-trehalose
def: "A trehalose in which both glucose residues have α-configuration at the anomeric carbon." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27082 ! trehalose
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:16555
name: ethanethioic S-acid
def: "A thioacetic acid that is acetic acid in which the oxygen atom of the hydroxy group has been replaced by a sulfur atom." []
is_a: CHEBI:26952 ! thioacetic acid
relationship: RO:0018036 CHEBI:46800 ! is tautomer of ethanethioic O-acid

[Term]
id: CHEBI:16566
name: sphinganine
def: "A 2-aminooctadecane-1,3-diol having (2<i>S</i>,3<i>R</i>)-configuration." []
synonym: "Sphinganine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:46968 ! 2-aminooctadecane-1,3-diol
relationship: RO:0000087 CHEBI:37700 ! has role EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:57817 ! is deprotonated form of sphinganine(1+)

[Term]
id: CHEBI:16573
name: carbonyl sulfide
def: "A one-carbon compound in which the carbon atom is attached to an oxygen and a sulfur atom via double bonds." []
synonym: "Carbonyl sulfide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:64708 ! one-carbon compound

[Term]
id: CHEBI:16579
name: anisole
def: "A monomethoxybenzene that is benzene substituted by a methoxy group." []
synonym: "Anisole" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25235 ! monomethoxybenzene
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:16598
name: DDE
def: "A chlorophenylethylene that is ethylene substituted by two 4-chlorophenyl groups at position 1 and two chlorine atoms at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23155 ! chlorophenylethylene
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:16602
name: trichloroethene
def: "A member of the class of  chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23142 ! chloroethenes
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:16605
name: allyl alcohol
def: "A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (<em>Allium sativum</em>). Formerly used as a herbicide for the control of various grass and weed seeds." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134394 ! primary allylic alcohol
is_a: CHEBI:26300 ! propenol
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:16610
name: spermidine
def: "A triamine that is the 1,5,10-triaza derivative of decane." []
is_a: CHEBI:38751 ! triamine
is_a: CHEBI:39474 ! polyazaalkane
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:138880 ! has role autophagy inducer
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:57834 ! is deprotonated form of spermidine(3+)

[Term]
id: CHEBI:16632
name: vanillate
def: "A methoxybenzoate that is the conjugate base of vanillic acid." []
synonym: "4-HYDROXY-3-METHOXYBENZOATE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25236 ! methoxybenzoate
is_a: CHEBI:25388 ! monohydroxybenzoate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:30816 ! is deprotonated form of vanillic acid

[Term]
id: CHEBI:16634
name: raffinose
def: "A trisaccharide composed of α-<small>D</small>-galactopyranose, α-<small>D</small>-glucopyranose and β-<small>D</small>-fructofuranose joined in sequence by 1→6 and 1↔2 glycosidic linkages, respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27150 ! trisaccharide
is_a: CHEBI:74961 ! raffinose family oligosaccharide
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:16646
name: carbohydrate
def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula C<small><sub><em>m</em></sub></small>(H<small><sub>2</sub></small>O)<small><sub><em>n</em></sub></small>. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." []
is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives

[Term]
id: CHEBI:16648
name: dialkyl phosphate
is_a: CHEBI:22324 ! alkyl phosphate
relationship: RO:0018034 CHEBI:138518 ! is protonated form of dialkyl phosphate(1-)

[Term]
id: CHEBI:16651
name: (S)-lactate
def: "An optically active form of lactate having (<i>S</i>)-configuration." []
is_a: CHEBI:24996 ! lactate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:422 ! is deprotonated form of (S)-lactic acid
relationship: RO:0018039 CHEBI:16004 ! is enantiomer of (R)-lactate

[Term]
id: CHEBI:166606
name: Urolithin B
is_a: CHEBI:234554 ! urolithin

[Term]
id: CHEBI:16670
name: peptide
def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from α-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." []
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:50047 ! organic amino compound
relationship: BFO:0000051 CHEBI:33708 ! has part amino-acid residue
relationship: RO:0018036 CHEBI:60466 ! is tautomer of peptide zwitterion

[Term]
id: CHEBI:166812
name: Secosterol-A
is_a: CHEBI:26658 ! sesquiterpenoid

[Term]
id: CHEBI:166829
name: ochratoxin A(1-)
def: "A monocarboxylic acid anion that is conjugate base of ochratoxin A, arising from the deprotonation of the carboxy group. Major microspecies at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:7719 ! is deprotonated form of ochratoxin A

[Term]
id: CHEBI:166831
name: copper chelator
def: "A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central copper atom at two or more points." []
is_a: CHEBI:38161 ! chelator

[Term]
id: CHEBI:166856
name: hydroxytrimethylaminium
def: "A methylated tertiary amine that is  trimethylammonium in which the hydrogen attached to the nitrogen is replaced by a hydroxy group." []
is_a: CHEBI:137983 ! methylated tertiary amine
is_a: CHEBI:33822 ! organic hydroxy compound
relationship: RO:0018034 CHEBI:15724 ! is protonated form of trimethylamine N-oxide
relationship: RO:0018038 CHEBI:58389 ! has functional parent trimethylammonium

[Term]
id: CHEBI:16688
name: ecdysone
def: "A 6-oxo steroid that is 5β-cholest-7-en-6-one substituted by hydroxy groups at positions 2, 3, 14, 22 and 25 respectively (the 2β, 3β, 22<i>R</i> stereoisomer). It is a steroid prohormone of the major insect moulting hormone 20-hydroxyecdysone." []
is_a: CHEBI:23897 ! ecdysteroid
is_a: CHEBI:35348 ! 3beta-sterol
is_a: CHEBI:36859 ! 2beta-hydroxy steroid
is_a: CHEBI:36861 ! 14alpha-hydroxy steroid
is_a: CHEBI:36863 ! 22-hydroxy steroid
is_a: CHEBI:36864 ! 25-hydroxy steroid
is_a: CHEBI:36883 ! 6-oxo steroid
relationship: RO:0000087 CHEBI:71212 ! has role prohormone
relationship: RO:0018040 CHEBI:35517 ! has parent hydride 5beta-cholestane

[Term]
id: CHEBI:166881
name: poly(ethylene-co-vinyl acetate)
def: "An elastomeric copolymer of ethylene and vinyl acetate used to produce \"rubber-like\" materials." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60804 ! copolymer
relationship: BFO:0000051 CHEBI:18153 ! has part ethene
relationship: BFO:0000051 CHEBI:46916 ! has part vinyl acetate
relationship: RO:0000087 CHEBI:79314 ! has role flame retardant

[Term]
id: CHEBI:166885
name: prolamin
def: "A group of plant storage proteins having a high proline amino acid content." []
is_a: CHEBI:746933 ! globular protein

[Term]
id: CHEBI:166902
name: noradrenaline(1+)
def: "An organic cation that is the conjugate acid of noradrenaline, obtained by protonation of the primary amino group; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:33569 ! is protonated form of noradrenaline

[Term]
id: CHEBI:16695
name: uridine 5'-monophosphate
def: "A pyrimidine ribonucleoside 5'-monophosphate having uracil as the nucleobase." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27232 ! uridine 5'-phosphate
is_a: CHEBI:39457 ! pyrimidine ribonucleoside 5'-monophosphate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:57865 ! is protonated form of uridine 5'-monophosphate(2-)

[Term]
id: CHEBI:166975
name: soybean oil
def: "An oil extracted from the seeds of <em>Glycine max</em>. Typical fatty acid composition is 51% linoleic acid, 7-10% α-linolenic acid, 23% oleic acid, 10% palmitic acid and 4% stearic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:15756 ! has part hexadecanoic acid
relationship: BFO:0000051 CHEBI:16196 ! has part oleic acid
relationship: BFO:0000051 CHEBI:17351 ! has part linoleic acid
relationship: BFO:0000051 CHEBI:27432 ! has part alpha-linolenic acid
relationship: BFO:0000051 CHEBI:28842 ! has part octadecanoic acid
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:50913 ! has role fixative
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:90753 ! has role antidote to organophosphate poisoning

[Term]
id: CHEBI:16698
name: cyanamide
def: "A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an amino group." []
synonym: "CYANAMIDE" EXACT [PDBeChem]
synonym: "Cyanamide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:35487 ! has role EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
relationship: RO:0018034 CHEBI:64302 ! is protonated form of cyanamide(2-)

[Term]
id: CHEBI:16701
name: nucleoside 5'-phosphate
def: "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated." []
is_a: CHEBI:29075 ! mononucleotide
relationship: RO:0018034 CHEBI:57867 ! is protonated form of nucleoside 5'-phosphate dianion

[Term]
id: CHEBI:16704
name: uridine
def: "A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a β‒N<small><sup>1</small></sup>-glycosidic bond." []
synonym: "URIDINE" EXACT [PDBeChem]
synonym: "Uridine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27242 ! uridines
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:16705
name: 6-aminopenicillanic acid
def: "A penicillanic acid compound having a (6<i>R</i>)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics." []
is_a: CHEBI:25865 ! penicillanic acids
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0018034 CHEBI:30938 ! is protonated form of 6-aminopenicillanate
relationship: RO:0018036 CHEBI:57869 ! is tautomer of 6-aminopenicillanic acid zwitterion
relationship: RO:0018038 CHEBI:37806 ! has functional parent penicillanic acid

[Term]
id: CHEBI:167055
name: Jasmonate derivatives
def: "Any octanoid that is derived from jasmonate." []
is_a: CHEBI:36326 ! octadecanoid

[Term]
id: CHEBI:16708
name: adenine
def: "The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:20706 ! 6-aminopurines
is_a: CHEBI:26386 ! purine nucleobase
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018040 CHEBI:35589 ! has parent hydride 9H-purine

[Term]
id: CHEBI:167095
name: secondary fatty alcohol
def: "A fatty alcohol consisting of a chain of 3 to greater than 27 carbon atoms in which a hydroxy group is attached to a saturated carbon atom different from the terminal carbons. Secondary fatty alcohols may be saturated or unsaturated and may be branched or unbranched." []
is_a: CHEBI:24026 ! fatty alcohol
is_a: CHEBI:35681 ! secondary alcohol

[Term]
id: CHEBI:167099
name: benzo[d]isothiazol-3-one
def: "An organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
relationship: RO:0000087 CHEBI:139492 ! has role sensitiser
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:167114
name: 2-hydroxydicarboxylate(2-)
def: "Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group. Major species at pH 7.3." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:50263 ! is deprotonated form of 2-hydroxydicarboxylic acid

[Term]
id: CHEBI:16714
name: codeine
def: "A  morphinane alkaloid found in the opium poppy, <em>Papaver somniferum var. album</em>; has analgesic, anti-tussive and anti-diarrhoeal properties." []
is_a: CHEBI:25418 ! morphinane alkaloid
is_a: CHEBI:38164 ! organic heteropentacyclic compound
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:60606 ! has role opioid receptor agonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018033 CHEBI:57871 ! is deprotonated form of codeine(1+)
relationship: RO:0018038 CHEBI:17303 ! has functional parent morphine

[Term]
id: CHEBI:16716
name: benzene
def: "A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised π system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system." []
synonym: "BENZENE" EXACT [PDBeChem]
synonym: "Benzene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:33842 ! aromatic annulene
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:167162
name: L-ascorbic acid 2-phosphate
def: "An aldonolactone phosphate that is the 2-phosphate ester of <small>L</small>-ascorbic acid. It can stimulate collagen formation." []
is_a: CHEBI:37429 ! aldonolactone phosphate
relationship: RO:0018034 CHEBI:167163 ! is protonated form of L-ascorbate 2-phosphate(3-)
relationship: RO:0018038 CHEBI:29073 ! has functional parent L-ascorbic acid

[Term]
id: CHEBI:167163
name: L-ascorbate 2-phosphate(3-)
def: "An organophosphate oxoanion that is the trianion formed from <small>L</small>-ascorbic acid 2-phosphate by deprotonation of the 3-hydroxy group and of both hydroxy groups of the phosphate function; major species at pH 7.3." []
is_a: CHEBI:58945 ! organophosphate oxoanion
is_a: CHEBI:63551 ! carbohydrate acid derivative anion
relationship: RO:0018033 CHEBI:167162 ! is deprotonated form of L-ascorbic acid 2-phosphate

[Term]
id: CHEBI:167164
name: mineral nutrient
def: "A mineral that is an inorganic nutrient which must be ingested and absorbed in adequate amounts to satisfy a wide range of essential metabolic and/or structural functions in the human body." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:46662 ! mineral
relationship: RO:0000087 CHEBI:33284 ! has role nutrient

[Term]
id: CHEBI:167165
name: kappa-opioid receptor antagonist
def: "Any compound that exhibits antagonist activity at the κ-opioid receptor." []
is_a: CHEBI:60603 ! kappa-opioid agent
is_a: CHEBI:60605 ! opioid receptor antagonist

[Term]
id: CHEBI:167183
name: piscicide
def: "A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:167204
name: 4-amino-5-chloro-2-ethoxy-N-(\{4-[(4-fluorophenyl)methyl]morpholin-2-yl\}methyl)benzamide
def: "A benzamide resulting from the formal condensation of the carboxy group of 4-amino-5-chloro-2-ethoxybenzoic acid with the amino group of 1-[4-(4-fluorobenzyl)morpholin-2-yl]methanamine." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:83575 ! monofluorobenzenes

[Term]
id: CHEBI:167205
name: (R)-mosapride
def: "A 4-amino-5-chloro-2-ethoxy-<em>N</em>-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide that has (<i>R</i>)-configuration." []
is_a: CHEBI:167204 ! 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide
relationship: RO:0018039 CHEBI:167206 ! is enantiomer of (S)-mosapride

[Term]
id: CHEBI:167206
name: (S)-mosapride
def: "A 4-amino-5-chloro-2-ethoxy-<em>N</em>-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide that has (<i>S</i>)-configuration." []
is_a: CHEBI:167204 ! 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide
relationship: RO:0018039 CHEBI:167205 ! is enantiomer of (R)-mosapride

[Term]
id: CHEBI:167308
name: dextromethadone
def: "A 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (<i>S</i>)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder." []
is_a: CHEBI:167309 ! 6-(dimethylamino)-4,4-diphenylheptan-3-one
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0018039 CHEBI:136003 ! is enantiomer of levomethadone

[Term]
id: CHEBI:167309
name: 6-(dimethylamino)-4,4-diphenylheptan-3-one
def: "A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4." []
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:51614 ! diarylmethane
relationship: RO:0018038 CHEBI:50139 ! has functional parent heptan-3-one

[Term]
id: CHEBI:16731
name: (E)-cinnamaldehyde
def: "The <i>E</i> (<i>trans</i>) stereoisomer of cinnamaldehyde, the parent of the class of cinnamaldehydes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:142921 ! 3-phenylprop-2-enal
relationship: RO:0000087 CHEBI:139492 ! has role sensitiser
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:62871 ! has role EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:16733
name: D-alpha-amino acid
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0018034 CHEBI:60895 ! is protonated form of D-alpha-amino acid anion
relationship: RO:0018036 CHEBI:59871 ! is tautomer of D-alpha-amino acid zwitterion

[Term]
id: CHEBI:16738
name: 2,4-dichlorophenol
def: "A dichlorophenol that is phenol carrying chloro substituents at positions 2 and 4." []
synonym: "2,4-Dichlorophenol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23702 ! dichlorophenol

[Term]
id: CHEBI:16739
name: 2-furoate
def: "A furancarboxylate that is the conjugate base of 2-furoic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36056 ! furancarboxylate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0018033 CHEBI:30845 ! is deprotonated form of 2-furoic acid

[Term]
id: CHEBI:167470
name: domoate(2-)
def: "A tricarboxylic acid anion that is the conjugate base of domoic acid, arising from the deprotonation of the carboxy groups and protonation of the pyrrolidine nitrogen. Major species at pH 7.3." []
is_a: CHEBI:35753 ! tricarboxylic acid anion
relationship: RO:0018033 CHEBI:34727 ! is deprotonated form of domoic acid

[Term]
id: CHEBI:16750
name: guanosine
def: "A purine nucleoside in which guanine is attached to ribofuranose via a β-<em>N</em><small><sup>9</small></sup>-glycosidic bond." []
synonym: "Guanosine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:142355 ! purines D-ribonucleoside
is_a: CHEBI:24458 ! guanosines
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:16753
name: pantetheine
def: "An amide obtained by formal condensation of the carboxy group of pantothenic acid and the amino group of cysteamine." []
is_a: CHEBI:25845 ! pantetheines
is_a: CHEBI:29256 ! thiol
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:16755
name: chenodeoxycholic acid
def: "A dihydroxy-5β-cholanic acid that is (5β)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively." []
is_a: CHEBI:131620 ! C24-steroid
is_a: CHEBI:23775 ! dihydroxy-5beta-cholanic acid
is_a: CHEBI:3098 ! bile acid
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:36234 ! is protonated form of chenodeoxycholate

[Term]
id: CHEBI:167559
name: glycan
def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also <a href=\"http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001\" target=\"_blank\">http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001</a>." []
is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives

[Term]
id: CHEBI:16761
name: ADP
def: "A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase." []
synonym: "Adenosine 5'-diphosphate" EXACT [KEGG_COMPOUND]
is_a: CHEBI:37038 ! purine ribonucleoside 5'-diphosphate
is_a: CHEBI:37096 ! adenosine 5'-phosphate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:87518 ! is protonated form of ADP(2-)

[Term]
id: CHEBI:167638
name: 2-hydroxy-5-\{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl\}benzamide
def: "A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5." []
is_a: CHEBI:140324 ! primary carboxamide
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:53443 ! salicylamides

[Term]
id: CHEBI:167639
name: (S,S)-labetalol
def: "A 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1<i>S</i>,2<i>S</i>-configuration." []
is_a: CHEBI:167638 ! 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide

[Term]
id: CHEBI:167640
name: (R,S)-labetolol
def: "A 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1<i>R</i>,2<i>S</i>-configuration." []
is_a: CHEBI:167638 ! 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide

[Term]
id: CHEBI:167641
name: (S,R)-labetolol
def: "A 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1<i>S</i>,2<i>R</i>-configuration." []
is_a: CHEBI:167638 ! 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide

[Term]
id: CHEBI:16765
name: tryptamine
def: "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." []
synonym: "2-(1H-INDOL-3-YL)ETHANAMINE" EXACT [PDBeChem]
is_a: CHEBI:27162 ! tryptamines
is_a: CHEBI:38631 ! aminoalkylindole
is_a: CHEBI:38958 ! indole alkaloid
is_a: CHEBI:64365 ! aralkylamino compound
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:57887 ! is deprotonated form of tryptaminium

[Term]
id: CHEBI:167670
name: SCH772984
def: "A member of the class of indazoles that is 1<em>H</em>-indazole substituted by pyridin-4-yl and {[(3<i>R</i>)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)pyrrolidin-3-yl]carbonyl}amino groups at positions 3 and 5, respectively. It is a potent inhibitor of mitogen-activated protein kinases ERK1 and ERK2 (IC<small><sub>50</sub></small> = 4 and 1 nM, respectively) that exhibits anti-cancer properties." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:38769 ! indazoles
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:46770 ! pyrrolidinecarboxamide
is_a: CHEBI:46775 ! N-alkylpyrrolidine
is_a: CHEBI:46844 ! N-acylpiperazine
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:64459 ! biaryl
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:79091 ! has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

[Term]
id: CHEBI:167868
name: morpholinium
def: "A secondary ammonium ion that is the conjugate acid of morpholine resulting from the protonation of the NH group. Major microspecies at pH 7.3." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:34856 ! is protonated form of morpholine

[Term]
id: CHEBI:16793
name: mercury(2+)
synonym: "mercury(2+) ion" EXACT [ChEBI]
synonym: "mercury(II) cation" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25197 ! mercury cation
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:16794
name: scopolamine
def: "A tropane alkaloid that is the (<i>S</i>)-tropic acid ester of 6β,7β-epoxy-1α<em>H</em>,5α<em>H</em>-tropan-3α-ol." []
is_a: CHEBI:32955 ! epoxide
is_a: CHEBI:36243 ! propanoate ester
is_a: CHEBI:37332 ! tropane alkaloid
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:48876 ! has role muscarinic antagonist
relationship: RO:0000087 CHEBI:50513 ! has role mydriatic agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:60807 ! has role anaesthesia adjuvant
relationship: RO:0018033 CHEBI:61269 ! is deprotonated form of scopolamine(1+)
relationship: RO:0018038 CHEBI:30766 ! has functional parent (S)-tropic acid

[Term]
id: CHEBI:16796
name: melatonin
def: "A member of the class of  acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1<em>H</em>-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:27162 ! tryptamines
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:24621 ! has role hormone
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018038 CHEBI:16765 ! has functional parent tryptamine

[Term]
id: CHEBI:16799
name: 16alpha-hydroxy steroid
def: "A 16-hydroxy steroid in which the hydroxy group at position 16 has α-configuration." []
is_a: CHEBI:36840 ! 16-hydroxy steroid

[Term]
id: CHEBI:16811
name: methionine
def: "A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4." []
synonym: "Methionine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26834 ! sulfur-containing amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32646 ! is deprotonated form of methioninium
relationship: RO:0018034 CHEBI:32644 ! is protonated form of methioninate
relationship: RO:0018036 CHEBI:64558 ! is tautomer of methionine zwitterion
relationship: RO:0018038 CHEBI:30772 ! has functional parent butyric acid

[Term]
id: CHEBI:16830
name: methylamine
def: "The simplest of the methylamines, consisting of ammonia bearing a single methyl substituent." []
synonym: "Methanamine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:17062 ! primary aliphatic amine
is_a: CHEBI:25274 ! methylamines
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:59338 ! is deprotonated form of methylammonium

[Term]
id: CHEBI:16836
name: 4-nitrophenol
def: "A member of the class of 4-nitrophenols that is phenol in which the hydrogen that is <em>para</em> to the hydroxy group has been replaced by a nitro group." []
synonym: "4-Nitrophenol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:88306 ! 4-nitrophenols
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:57917 ! is protonated form of 4-nitrophenolate

[Term]
id: CHEBI:168396
name: mycophenolic acid
def: "A member of the class of 2-benzofurans that is 2-benzofuran-1(3<em>H</em>)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2<i>E</i>)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by <em>Penicillium brevi-compactum, P. stoloniferum, P. echinulatum</em> and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:37581 ! gamma-lactone
is_a: CHEBI:38831 ! 2-benzofurans
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:25442 ! has role mycotoxin
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:53746 ! has role EC 1.1.1.205 (IMP dehydrogenase) inhibitor
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76964 ! has role Penicillium metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:62932 ! is protonated form of mycophenolate
relationship: RO:0018038 CHEBI:38355 ! has functional parent hex-4-enoic acid

[Term]
id: CHEBI:16842
name: formaldehyde
def: "An aldehyde resulting from the formal oxidation of methanol." []
synonym: "Formaldehyde" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:16855
name: D-lysine
def: "The <small>D</small>-enantiomer of the α-amino acid lysine." []
synonym: "D-LYSINE" EXACT [PDBeChem]
synonym: "D-Lysine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:25094 ! lysine
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:32557 ! is deprotonated form of D-lysinium(1+)
relationship: RO:0018034 CHEBI:32556 ! is protonated form of D-lysinate
relationship: RO:0018039 CHEBI:18019 ! is enantiomer of L-lysine

[Term]
id: CHEBI:16856
name: glutathione
def: "A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine." []
is_a: CHEBI:29256 ! thiol
is_a: CHEBI:47923 ! tripeptide
is_a: CHEBI:83824 ! L-cysteine derivative
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:85046 ! has role skin lightening agent
relationship: RO:0018034 CHEBI:57925 ! is protonated form of glutathionate(1-)

[Term]
id: CHEBI:16857
name: L-threonine
def: "An optically active form of threonine having <small>L</small>-configuration." []
synonym: "L-Threonine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22658 ! aspartate family amino acid
is_a: CHEBI:26986 ! threonine
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32822 ! is deprotonated form of L-threoninium
relationship: RO:0018034 CHEBI:32820 ! is protonated form of L-threoninate
relationship: RO:0018036 CHEBI:57926 ! is tautomer of L-threonine zwitterion
relationship: RO:0018039 CHEBI:16398 ! is enantiomer of D-threonine

[Term]
id: CHEBI:16862
name: nucleoside 5'-diphosphate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25608 ! nucleoside phosphate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:57930 ! is protonated form of nucleoside 5'-diphosphate(3-)

[Term]
id: CHEBI:168630
name: Chlorin E6
is_a: CHEBI:33910 ! chlorins

[Term]
id: CHEBI:16865
name: gamma-aminobutyric acid
def: "A γ-amino acid that is butanoic acid with the amino substituent located at C-4." []
synonym: "4-Aminobutanoic acid" EXACT [KEGG_COMPOUND]
synonym: "4-aminobutanoic acid" EXACT [ChEBI]
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33707 ! gamma-amino acid
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:30566 ! is protonated form of gamma-aminobutyrate
relationship: RO:0018036 CHEBI:59888 ! is tautomer of gamma-aminobutyric acid zwitterion
relationship: RO:0018038 CHEBI:30772 ! has functional parent butyric acid
relationship: RO:0018038 CHEBI:33707 ! has functional parent gamma-amino acid

[Term]
id: CHEBI:16891
name: glyoxylic acid
def: "A 2-oxo monocarboxylic acid that is acetic acid bearing an oxo group at the α carbon atom." []
is_a: CHEBI:26643 ! aldehydic acid
is_a: CHEBI:35910 ! 2-oxo monocarboxylic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:36655 ! is protonated form of glyoxylate

[Term]
id: CHEBI:16899
name: D-mannitol
def: "The <small>D</small>-enantiomer of mannitol." []
synonym: "D-Mannitol" EXACT [KEGG_COMPOUND]
synonym: "D-mannitol" EXACT [ChEBI]
synonym: "Mannitol" EXACT [KEGG_COMPOUND]
synonym: "mannitol" EXACT [ChEMBL]
is_a: CHEBI:29864 ! mannitol
relationship: RO:0000087 CHEBI:23366 ! has role compatible osmolytes
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:50504 ! has role osmotic diuretic
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:59174 ! has role hapten
relationship: RO:0000087 CHEBI:77965 ! has role food anticaking agent
relationship: RO:0000087 CHEBI:77966 ! has role food stabiliser
relationship: RO:0000087 CHEBI:77969 ! has role food humectant
relationship: RO:0000087 CHEBI:77970 ! has role food thickening agent
relationship: RO:0000087 CHEBI:78004 ! has role food bulking agent

[Term]
id: CHEBI:16907
name: 4-nitroquinoline N-oxide
def: "A quinoline <em>N</em>-oxide carrying a nitro substituent at position 4." []
synonym: "4-Nitroquinoline 1-oxide" EXACT [KEGG_COMPOUND]
synonym: "4-nitroquinoline 1-oxide" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26508 ! quinoline N-oxide
is_a: CHEBI:35716 ! C-nitro compound
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:16914
name: salicylic acid
def: "A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the <em>ortho</em> position. It is obtained from the bark of the white willow and wintergreen leaves." []
synonym: "2-HYDROXYBENZOIC ACID" EXACT [PDBeChem]
is_a: CHEBI:25389 ! monohydroxybenzoic acid
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:37848 ! has role plant hormone
relationship: RO:0000087 CHEBI:50176 ! has role keratolytic drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73181 ! has role EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:30762 ! is protonated form of salicylate
relationship: RO:0018038 CHEBI:16914 ! has functional parent salicylic acid

[Term]
id: CHEBI:16918
name: gallate
def: "A trihydroxybenzoate that is the conjugate base of gallic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36085 ! trihydroxybenzoate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:30778 ! is deprotonated form of gallic acid

[Term]
id: CHEBI:16933
name: ergosterol
def: "A phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3β-hydroxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:1722 ! 3beta-hydroxy-Delta(5)-steroid
is_a: CHEBI:26125 ! phytosterols
is_a: CHEBI:35348 ! 3beta-sterol
is_a: CHEBI:50403 ! ergostanoid
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite

[Term]
id: CHEBI:16934
name: 3-cyano-L-alanine
def: "A cyanoamino acid that is the 3-cyano-derivative of <small>L</small>-alanine." []
synonym: "3-Cyano-L-alanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:60974 ! cyanoamino acid
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:57954 ! is protonated form of 3-cyano-L-alaninate
relationship: RO:0018036 CHEBI:77860 ! is tautomer of 3-cyano-L-alanine zwitterion

[Term]
id: CHEBI:16947
name: citrate(3-)
def: "A tricarboxylic acid trianion, obtained by deprotonation of the three carboxy groups of citric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133748 ! citrate anion
is_a: CHEBI:27092 ! tricarboxylic acid trianion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:35808 ! is deprotonated form of citrate(2-)
relationship: RO:0018034 CHEBI:132362 ! is protonated form of citrate(4-)

[Term]
id: CHEBI:16958
name: beta-alanine
def: "A naturally-occurring β-amino acid comprising propionic acid with the amino group in the 3-position." []
synonym: "BETA-ALANINE" EXACT [PDBeChem]
synonym: "beta-Alanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33706 ! beta-amino acid
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:35222 ! has role inhibitor
relationship: RO:0000087 CHEBI:48705 ! has role agonist
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:63070 ! is protonated form of beta-alaninate
relationship: RO:0018036 CHEBI:57966 ! is tautomer of beta-alanine zwitterion

[Term]
id: CHEBI:16961
name: monoacylglycerol phosphate
def: "Derivatives of phosphoglycerols which have only one of the alcohol groups of the glycerol backbone ester-linked with a fatty acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26707 ! glycerol phosphate
is_a: CHEBI:37739 ! glycerophospholipid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:16962
name: cortisone
def: "A C<small><sub>21</sub></small>-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:47787 ! 11-oxo steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:61313 ! C21-steroid
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:16966
name: heteroglycan
def: "A polysaccharide composed of two or more different types of monosaccharides," []
is_a: CHEBI:18154 ! polysaccharide

[Term]
id: CHEBI:16973
name: 11-deoxycorticosterone
def: "A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:25354 ! mineralocorticoid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018038 CHEBI:17026 ! has functional parent progesterone

[Term]
id: CHEBI:16975
name: 1-acyl-sn-glycerol 3-phosphate
is_a: CHEBI:17088 ! monoacyl-sn-glycerol 3-phosphate
is_a: CHEBI:76629 ! 2-lysophosphatidic acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:57970 ! is protonated form of 1-acyl-sn-glycerol 3-phosphate(2-)

[Term]
id: CHEBI:16977
name: L-alanine
def: "The <small>L</small>-enantiomer of alanine." []
synonym: "ALANINE" EXACT [PDBeChem]
synonym: "L-Alanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16449 ! alanine
is_a: CHEBI:26463 ! pyruvate family amino acid
relationship: RO:0000087 CHEBI:77881 ! has role EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
relationship: RO:0018033 CHEBI:32432 ! is deprotonated form of L-alaninium
relationship: RO:0018034 CHEBI:32431 ! is protonated form of L-alaninate
relationship: RO:0018036 CHEBI:57972 ! is tautomer of L-alanine zwitterion
relationship: RO:0018039 CHEBI:15570 ! is enantiomer of D-alanine

[Term]
id: CHEBI:16988
name: D-ribose
def: "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in <small>D</small>-glyceraldehyde." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33942 ! ribose
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018039 CHEBI:46997 ! is enantiomer of L-ribose

[Term]
id: CHEBI:16990
name: bilirubin IXalpha
def: "A member of the class of  biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." []
synonym: "Bilirubin" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35692 ! dicarboxylic acid
is_a: CHEBI:36735 ! biladienes
relationship: BFO:0000051 CHEBI:142163 ! has part 24G7 epitope
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:57977 ! is protonated form of bilirubin(2-)

[Term]
id: CHEBI:16991
name: deoxyribonucleic acid
def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33696 ! nucleic acid
relationship: BFO:0000051 CHEBI:33793 ! has part canonical deoxyribonucleoside residue
relationship: BFO:0000051 CHEBI:50298 ! has part canonical deoxyribonucleotide residue
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:16995
name: oxalic acid
def: "An α,ω-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2." []
synonym: "OXALIC ACID" EXACT [PDBeChem]
synonym: "Oxalic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:28383 ! alpha,omega-dicarboxylic acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:46904 ! is protonated form of oxalate(1-)

[Term]
id: CHEBI:169952
name: 13-cis-retinoate
is_a: CHEBI:15036 ! retinoate
relationship: RO:0018033 CHEBI:6067 ! is deprotonated form of isotretinoin

[Term]
id: CHEBI:16997
name: propane-1,2-diol
def: "The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (−59°C) and high-boiling (188°C) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze." []
synonym: "Propane-1,2-diol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26284 ! propane-1,2-diols
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite

[Term]
id: CHEBI:16998
name: D-phenylalanine
def: "The <small>D</small>-enantiomer of phenylalanine." []
synonym: "D-PHENYLALANINE" EXACT [PDBeChem]
synonym: "D-Phenylalanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:28044 ! phenylalanine
relationship: RO:0018033 CHEBI:32495 ! is deprotonated form of D-phenylalaninium
relationship: RO:0018034 CHEBI:32494 ! is protonated form of D-phenylalaninate
relationship: RO:0018036 CHEBI:57981 ! is tautomer of D-phenylalanine zwitterion
relationship: RO:0018039 CHEBI:17295 ! is enantiomer of L-phenylalanine

[Term]
id: CHEBI:17000
name: tropate
def: "A hydroxy monocarboxylic acid anion that results from the deprotonation of the carboxylic acid group of tropic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:30765 ! is deprotonated form of tropic acid
relationship: RO:0018038 CHEBI:17272 ! has functional parent propionate

[Term]
id: CHEBI:17015
name: riboflavin
def: "<small>D</small>-Ribitol in which the hydroxy group at position 5 is substituted by a 7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[<em>g</em>]pteridin-10(2<em>H</em>)-yl moiety. It is a nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables, but the richest natural source is yeast. The free form occurs only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide." []
is_a: CHEBI:176838 ! vitamin B2
is_a: CHEBI:30527 ! flavin
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77182 ! has role food colouring
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018034 CHEBI:57986 ! is protonated form of riboflavin(1-)

[Term]
id: CHEBI:17026
name: progesterone
def: "A C<small><sub>21</sub></small>-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species." []
is_a: CHEBI:36699 ! corticosteroid hormone
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:64600 ! C21-steroid hormone
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:49323 ! has role contraceptive drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:59826 ! has role progestin
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:70709 ! has role progesterone receptor agonist
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:17029
name: chitin
def: "An aminoglycan consisting of β-(1→4)-linked <em>N</em>-acetyl-<small>D</small>-glucosamine residues." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:21638 ! N-acylglucosamine
is_a: CHEBI:22506 ! aminoglycan
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:17043
name: biphenyl-2-ol
def: "A member of the class of hydroxybiphenyls that is biphenyl substituted by a hydroxy group at position 2. It is generally used as a post-harvest fungicide for citrus fruits." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24681 ! hydroxybiphenyls
relationship: RO:0000087 CHEBI:78299 ! has role environmental food contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018040 CHEBI:17097 ! has parent hydride biphenyl

[Term]
id: CHEBI:17045
name: dinitrogen oxide
def: "A nitrogen oxide consisting of linear unsymmetrical molecules with formula N<small><sub>2</sub></small>O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream." []
synonym: "Dinitrogen oxide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:35196 ! nitrogen oxide
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77971 ! has role raising agent
relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas
relationship: RO:0000087 CHEBI:78017 ! has role food propellant
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:17051
name: fluoride
synonym: "Fluoride" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16042 ! halide anion
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:36895 ! monoatomic fluorine
relationship: RO:0018033 CHEBI:29228 ! is deprotonated form of hydrogen fluoride

[Term]
id: CHEBI:17053
name: L-aspartic acid
def: "The <small>L</small>-enantiomer of aspartic acid." []
synonym: "ASPARTIC ACID" EXACT [PDBeChem]
synonym: "L-Aspartic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22658 ! aspartate family amino acid
is_a: CHEBI:22660 ! aspartic acid
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:29991 ! is protonated form of L-aspartate(1-)
relationship: RO:0018039 CHEBI:17364 ! is enantiomer of D-aspartic acid

[Term]
id: CHEBI:17057
name: cellobiose
def: "A glycosylglucose consisting of two glucose units linked via a β(1→4) bond." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24405 ! glycosylglucose
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:17061
name: D-glutamine
def: "The <small>D</small>-enantiomer of glutamine." []
synonym: "D-Glutamine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:28300 ! glutamine
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:32673 ! is deprotonated form of D-glutaminium
relationship: RO:0018034 CHEBI:32672 ! is protonated form of D-glutaminate
relationship: RO:0018036 CHEBI:58000 ! is tautomer of D-glutamine zwitterion
relationship: RO:0018039 CHEBI:18050 ! is enantiomer of L-glutamine

[Term]
id: CHEBI:17062
name: primary aliphatic amine
is_a: CHEBI:32877 ! primary amine
relationship: RO:0018033 CHEBI:58001 ! is deprotonated form of primary aliphatic ammonium ion

[Term]
id: CHEBI:17064
name: 4-nitroaniline
def: "A nitroaniline carrying a nitro group at position 4." []
synonym: "4-NITROANILINE" EXACT [PDBeChem]
synonym: "4-Nitroaniline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25550 ! nitroaniline
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite

[Term]
id: CHEBI:17076
name: streptomycin
def: "A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class" []
is_a: CHEBI:26788 ! streptomycins
is_a: CHEBI:87113 ! antibiotic antifungal drug
is_a: CHEBI:87114 ! antibiotic fungicide
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018033 CHEBI:58007 ! is deprotonated form of streptomycin(3+)
relationship: RO:0018038 CHEBI:27405 ! has functional parent streptidine

[Term]
id: CHEBI:17084
name: 2-hydroxyglutaric acid
def: "A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen α- to a carboxylic acid group is substituted by a hydroxy group." []
is_a: CHEBI:189840 ! dicarboxylic fatty acid
is_a: CHEBI:50263 ! 2-hydroxydicarboxylic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:36149 ! is protonated form of 2-hydroxyglutarate(1-)
relationship: RO:0018038 CHEBI:17859 ! has functional parent glutaric acid

[Term]
id: CHEBI:17087
name: ketone
def: "A compound in which a carbonyl group is bonded to two carbon atoms: R<small><sub>2</sub></small>C=O (neither R may be H)." []
synonym: "ketones" EXACT [ChEBI]
is_a: CHEBI:36586 ! carbonyl compound

[Term]
id: CHEBI:17088
name: monoacyl-sn-glycerol 3-phosphate
def: "An <em>sn</em>-glycero-3-phosphate compound having a single unspecified acyl group at either position 1 or position 2." []
is_a: CHEBI:16961 ! monoacylglycerol phosphate
is_a: CHEBI:26706 ! sn-glycerol 3-phosphates
relationship: RO:0018034 CHEBI:77589 ! is protonated form of monoacyl-sn-glycerol 3-phosphate(2-)

[Term]
id: CHEBI:17089
name: glycoprotein
def: "A compound in which a carbohydrate component is covalently bound to a protein component." []
is_a: CHEBI:33837 ! conjugated protein
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:17097
name: biphenyl
def: "A benzenoid aromatic compound that consists of two benzene rings connected by a single covalent bond. Biphenyl occurs naturally in coal tar, crude oil, and natural gas. Formerly used as a fungicide for citrus crops." []
synonym: "1,1'-Biphenyl" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:87034 ! aromatic fungicide
relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:17102
name: phosphoramide
def: "A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR<small><sub>2</sub></small>)<small><sub>3</sub></small>, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR<small><sub>2</sub></small>)<small><sub>2</sub></small> , P(=O)(OH)<small><sub>2</sub></small>(NR<small><sub>2</sub></small>)." []
is_a: CHEBI:33256 ! primary amide
relationship: RO:0018038 CHEBI:26078 ! has functional parent phosphoric acid

[Term]
id: CHEBI:17115
name: L-serine
def: "The <small>L</small>-enantiomer of serine." []
synonym: "L-Serine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:15705 ! L-alpha-amino acid
is_a: CHEBI:17822 ! serine
is_a: CHEBI:26650 ! serine family amino acid
is_a: CHEBI:83813 ! proteinogenic amino acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32837 ! is deprotonated form of L-serinium
relationship: RO:0018034 CHEBI:32836 ! is protonated form of L-serinate
relationship: RO:0018036 CHEBI:33384 ! is tautomer of L-serine zwitterion
relationship: RO:0018039 CHEBI:16523 ! is enantiomer of D-serine

[Term]
id: CHEBI:17120
name: hexanoate
def: "A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58951 ! short-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:78116 ! fatty acid anion 6:0
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30776 ! is deprotonated form of hexanoic acid

[Term]
id: CHEBI:17126
name: carnitine
def: "An amino-acid betaine that is butanoate substituted with a hydroxy group at position C-3 and a trimethylammonium group at C-4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22860 ! amino-acid betaine
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:3424 ! is deprotonated form of carnitinium
relationship: RO:0018038 CHEBI:17968 ! has functional parent butyrate

[Term]
id: CHEBI:17137
name: hydrogensulfite
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:48854 ! is deprotonated form of sulfurous acid
relationship: RO:0018034 CHEBI:17359 ! is protonated form of sulfite

[Term]
id: CHEBI:17141
name: cysteamine
def: "An amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2." []
synonym: "2-Aminoethanethiol" EXACT [KEGG_COMPOUND]
synonym: "2-aminoethanethiol" EXACT [ChEBI]
is_a: CHEBI:32952 ! amine
is_a: CHEBI:47908 ! alkanethiol
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:66987 ! has role radiation protective agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:58029 ! is deprotonated form of cysteaminium
relationship: RO:0018038 CHEBI:15862 ! has functional parent ethylamine

[Term]
id: CHEBI:17148
name: putrescine
def: "A four-carbon alkane-α,ω-diamine. It is obtained by the breakdown of amino acids and is responsible for the foul odour of putrefying flesh." []
is_a: CHEBI:35411 ! alkane-alpha,omega-diamine
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:326268 ! is deprotonated form of 1,4-butanediammonium

[Term]
id: CHEBI:17153
name: propanal
def: "An aldehyde that consists of ethane bearing a formyl substituent. The parent of the class of propanals." []
synonym: "Propionaldehyde" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26282 ! propanals
is_a: CHEBI:73359 ! alpha-CH2-containing aldehyde
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:17154
name: nicotinamide
def: "A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group." []
is_a: CHEBI:176839 ! vitamin B3
is_a: CHEBI:25529 ! pyridinecarboxamide
is_a: CHEBI:26416 ! pyridine alkaloid
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:62913 ! has role EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:71181 ! has role Sir2 inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018038 CHEBI:15940 ! has functional parent nicotinic acid

[Term]
id: CHEBI:17158
name: methylglyoxal
def: "A 2-oxo aldehyde derived from propanal." []
synonym: "2-Oxopropanal" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26282 ! propanals
is_a: CHEBI:27659 ! 2-oxo aldehyde
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:171664
name: antiamoebic agent
def: "An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae." []
is_a: CHEBI:35442 ! antiparasitic agent

[Term]
id: CHEBI:17170
name: dimethylamine
def: "A secondary aliphatic amine where both <em>N</em>-substituents are methyl." []
is_a: CHEBI:25274 ! methylamines
is_a: CHEBI:50981 ! secondary aliphatic amine
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018033 CHEBI:58040 ! is deprotonated form of dimethylaminium

[Term]
id: CHEBI:17184
name: chlordecone alcohol
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:17187
name: pinene
is_a: CHEBI:35187 ! monoterpene
relationship: RO:0018040 CHEBI:35710 ! has parent hydride pinane

[Term]
id: CHEBI:17188
name: nucleoside 5'-monophosphate
is_a: CHEBI:25608 ! nucleoside phosphate
relationship: RO:0018034 CHEBI:58043 ! is protonated form of nucleoside 5'-monophosphate(2-)

[Term]
id: CHEBI:17192
name: 3,5-dibromo-4-hydroxybenzonitrile
def: "A dibromobenzene that is 2,6-dibromophenol substituted by a cyano group at position 4." []
synonym: "3,5-Dibromo-4-hydroxybenzonitrile" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24730 ! hydroxynitrile
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:37147 ! dibromobenzene
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:58046 ! is protonated form of 3,5-dibromo-4-oxidobenzonitrile(1-)
relationship: RO:0018038 CHEBI:19391 ! has functional parent 2,6-dibromophenol

[Term]
id: CHEBI:17194
name: bromochloromethane
def: "A halomethane that is chloromethane in which one of the hydrogens has been replaced by a bromine atom." []
is_a: CHEBI:39279 ! halomethane

[Term]
id: CHEBI:17196
name: L-asparagine
def: "An optically active form of asparagine having <small>L</small>-configuration." []
synonym: "ASPARAGINE" EXACT [PDBeChem]
synonym: "L-Asparagine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22653 ! asparagine
is_a: CHEBI:22658 ! aspartate family amino acid
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32651 ! is deprotonated form of L-asparaginium
relationship: RO:0018034 CHEBI:32650 ! is protonated form of L-asparaginate
relationship: RO:0018036 CHEBI:58048 ! is tautomer of L-asparagine zwitterion
relationship: RO:0018039 CHEBI:28159 ! is enantiomer of D-asparagine

[Term]
id: CHEBI:17202
name: IMP
def: "A purine ribonucleoside 5'-monophosphate having hypoxanthine as the nucleobase." []
synonym: "5'-Inosinic acid" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24843 ! inosine phosphate
is_a: CHEBI:37021 ! purine ribonucleoside 5'-monophosphate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:58053 ! is protonated form of IMP(2-)

[Term]
id: CHEBI:17203
name: L-proline
def: "Pyrrolidine in which the <em>pro</em>-<i>S</i> hydrogen at position 2 is substituted by a carboxylic acid group. <small>L</small>-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group α to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles." []
synonym: "L-Proline" EXACT [KEGG_COMPOUND]
synonym: "PROLINE" EXACT [PDBeChem]
is_a: CHEBI:24318 ! glutamine family amino acid
is_a: CHEBI:26271 ! proline
relationship: RO:0000087 CHEBI:23366 ! has role compatible osmolytes
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32864 ! is deprotonated form of L-prolinium
relationship: RO:0018034 CHEBI:32862 ! is protonated form of L-prolinate
relationship: RO:0018036 CHEBI:60039 ! is tautomer of L-proline zwitterion
relationship: RO:0018039 CHEBI:16313 ! is enantiomer of D-proline

[Term]
id: CHEBI:17217
name: 2-butenoic acid
def: "A butenoic acid having the double bond at position C-2." []
is_a: CHEBI:22959 ! butenoic acid
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
relationship: RO:0018034 CHEBI:36258 ! is protonated form of but-2-enoate

[Term]
id: CHEBI:1722
name: 3beta-hydroxy-Delta(5)-steroid
def: "Any 3β-hydroxy-steroid that contains a double bond between positions 5 and 6." []
is_a: CHEBI:36836 ! 3beta-hydroxy steroid

[Term]
id: CHEBI:17231
name: m-cresol
def: "A cresol with the methyl substituent at position 3. It is a minor urinary metabolite of toluene." []
is_a: CHEBI:25399 ! cresol
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite

[Term]
id: CHEBI:17234
name: glucose
def: "An aldohexose used as a source of energy and metabolic intermediate." []
synonym: "Glucose" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33917 ! aldohexose
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:172368
name: brominated flame retardant
def: "Any organobromine compound that is used as a flame retardant. These chemicals are widely incorporated as additives in consumer products such as electronics, vehicles, polyurethane foams etc, to make them less flammable." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37141 ! organobromine compound
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0000087 CHEBI:79314 ! has role flame retardant

[Term]
id: CHEBI:172390
name: glycol ether
def: "A hydroxyether which contains both an ether and alcohol functional groups. It is one of the most versatile classes of organic solvents which are commonly used in paints, cleaners, adhesives, pharmaceuticals and cosmetics." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:46789 ! hydroxyether
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0018038 CHEBI:13643 ! has functional parent glycol

[Term]
id: CHEBI:172397
name: perfluoroalkyl substance
def: "A perfluorinated compound in which the carbon chain atoms are completely fluorinated." []
is_a: CHEBI:134091 ! perfluorinated compound

[Term]
id: CHEBI:17240
name: itaconate(2-)
def: "A dicarboxylic acid dianion that results from the deprotonation of both of the carboxylic acid groups of itaconic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30838 ! is deprotonated form of itaconic acid
relationship: RO:0018038 CHEBI:30031 ! has functional parent succinate(2-)

[Term]
id: CHEBI:172406
name: polyfluoroalkyl substance
def: "An organofluorine compound that has multiple fluorine atoms attached to an alkyl chain (but at least one of the carbon atoms in the chain is not fully fluorinated)." []
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:17241
name: 1H-pyrazole
def: "The 1<em>H</em>-tautomer of pyrazole." []
synonym: "PYRAZOLE" EXACT [PDBeChem]
synonym: "Pyrazole" EXACT [KEGG_COMPOUND]
is_a: CHEBI:14973 ! pyrazole
relationship: RO:0018033 CHEBI:33140 ! is deprotonated form of pyrazolium
relationship: RO:0018034 CHEBI:30367 ! is protonated form of pyrazol-1-ide
relationship: RO:0018036 CHEBI:38595 ! is tautomer of 3H-pyrazole
relationship: RO:0018036 CHEBI:38599 ! is tautomer of 4H-pyrazole

[Term]
id: CHEBI:17242
name: dehydroascorbic acid
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47016 ! tetrahydrofuranone
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:58070 ! is protonated form of dehydroascorbide(1-)
relationship: RO:0018038 CHEBI:22652 ! has functional parent ascorbic acid

[Term]
id: CHEBI:17245
name: carbon monoxide
def: "A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas." []
synonym: "CARBON MONOXIDE" EXACT [PDBeChem]
synonym: "Carbon monoxide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:23014 ! carbon oxide
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38500 ! has role EC 1.9.3.1 (cytochrome c oxidase) inhibitor
relationship: RO:0000087 CHEBI:50183 ! has role P450 inhibitor
relationship: RO:0000087 CHEBI:50406 ! has role probe
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:52214 ! has role ligand
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:58072 ! is deprotonated form of carbon monoxide(1+)

[Term]
id: CHEBI:17258
name: 7H-purine
def: "The 7<em>H</em>-tautomer of purine." []
synonym: "Purine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35584 ! purine
relationship: RO:0018036 CHEBI:35586 ! is tautomer of 1H-purine
relationship: RO:0018036 CHEBI:35588 ! is tautomer of 3H-purine
relationship: RO:0018036 CHEBI:35589 ! is tautomer of 9H-purine

[Term]
id: CHEBI:17263
name: estrone
def: "A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:177917 ! phenolic steroid
is_a: CHEBI:19168 ! 17-oxo steroid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50114 ! has role estrogen
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018040 CHEBI:23966 ! has parent hydride estrane

[Term]
id: CHEBI:17272
name: propionate
def: "The conjugate base of propionic acid; a key precursor in lipid biosynthesis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:78113 ! fatty acid anion 3:0
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30768 ! is deprotonated form of propionic acid

[Term]
id: CHEBI:17295
name: L-phenylalanine
def: "The <small>L</small>-enantiomer of phenylalanine." []
synonym: "L-Phenylalanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:28044 ! phenylalanine
is_a: CHEBI:73690 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:63332 ! has role EC 3.1.3.1 (alkaline phosphatase) inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32487 ! is deprotonated form of L-phenylalaninium
relationship: RO:0018034 CHEBI:32486 ! is protonated form of L-phenylalaninate
relationship: RO:0018036 CHEBI:58095 ! is tautomer of L-phenylalanine zwitterion
relationship: RO:0018039 CHEBI:16998 ! is enantiomer of D-phenylalanine

[Term]
id: CHEBI:17296
name: aniline
def: "A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens." []
synonym: "ANILINE" EXACT [PDBeChem]
synonym: "Aniline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22562 ! anilines
is_a: CHEBI:50471 ! primary arylamine

[Term]
id: CHEBI:17300
name: tetrachloroethene
def: "A chlorocarbon that is tetrachloro substituted ethene." []
synonym: "Tetrachloroethene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23142 ! chloroethenes
is_a: CHEBI:39226 ! chlorocarbon
relationship: RO:0000087 CHEBI:50909 ! has role nephrotoxic agent

[Term]
id: CHEBI:17303
name: morphine
def: "A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in <em>Papaver somniferum</em> (the opium poppy)." []
is_a: CHEBI:25418 ! morphinane alkaloid
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38867 ! has role anaesthetic
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018033 CHEBI:58097 ! is deprotonated form of morphine(1+)
relationship: RO:0018040 CHEBI:35649 ! has parent hydride morphinan

[Term]
id: CHEBI:17306
name: maltose
def: "A glycosylglucose consisting of two <small>D</small>-glucopyranose units connected by an α-(1→4)-linkage." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17593 ! maltooligosaccharide
is_a: CHEBI:24405 ! glycosylglucose
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:173084
name: ferroptosis inhibitor
def: "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:173085
name: ferroptosis inducer
def: "Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:173086
name: ferrostatin-1
def: "An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals." []
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50471 ! primary arylamine
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:66987 ! has role radiation protective agent

[Term]
id: CHEBI:17322
name: chloric acid
synonym: "Chloric acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33426 ! chlorine oxoacid
relationship: RO:0018034 CHEBI:49709 ! is protonated form of chlorate

[Term]
id: CHEBI:17326
name: nucleoside 5'-triphoshate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25608 ! nucleoside phosphate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:58104 ! is protonated form of nucleoside 5'-triphoshate(3-)

[Term]
id: CHEBI:17334
name: penicillin
def: "Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6." []
is_a: CHEBI:25865 ! penicillanic acids
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0018034 CHEBI:51356 ! is protonated form of penicillinate anion
relationship: RO:0018038 CHEBI:16705 ! has functional parent 6-aminopenicillanic acid

[Term]
id: CHEBI:17336
name: all-trans-retinol
def: "A retinol in which all four exocyclic double bonds have <i>E</i>- (<i>trans</i>-) geometry." []
synonym: "all-trans-Retinol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:12777 ! vitamin A
is_a: CHEBI:50211 ! retinol
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:17345
name: guanosine 5'-monophosphate
def: "A purine ribonucleoside 5'-monophosphate having guanine as the nucleobase." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37021 ! purine ribonucleoside 5'-monophosphate
is_a: CHEBI:37121 ! guanosine 5'-phosphate
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:58115 ! is protonated form of guanosine 5'-monophosphate(2-)

[Term]
id: CHEBI:17347
name: testosterone
def: "An androstanoid having 17β-hydroxy and 3-oxo groups, together with unsaturation at C-4‒C-5.." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131621 ! C19-steroid
is_a: CHEBI:35343 ! 17beta-hydroxy steroid
is_a: CHEBI:36834 ! 3-hydroxy steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:50402 ! androstanoid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50113 ! has role androgen
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite

[Term]
id: CHEBI:17351
name: linoleic acid
def: "An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have <i>Z</i> (<i>cis</i>) stereochemistry." []
is_a: CHEBI:25627 ! octadecadienoic acid
is_a: CHEBI:36009 ! omega-6 fatty acid
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:83038 ! has role Daphnia galeata metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:30245 ! is protonated form of linoleate

[Term]
id: CHEBI:17354
name: 16beta-hydroxy steroid
def: "A 16-hydroxy steroid in which the hydroxy group at position 16 has a β-configuration." []
is_a: CHEBI:36840 ! 16-hydroxy steroid

[Term]
id: CHEBI:17356
name: 2-acetamidofluorene
def: "The parent of the class of 2-acetamidofluorenes, being an <em>ortho</em>-fused polycyclic arene that consists of 9<em>H</em>-fluorene bearing an acetamido substituent at position 2. It is a carcinogenic and mutagenic derivative of fluorene." []
is_a: CHEBI:19432 ! 2-acetamidofluorenes
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:53000 ! has role epitope
relationship: RO:0000087 CHEBI:64911 ! has role antimitotic

[Term]
id: CHEBI:17359
name: sulfite
def: "A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H<small><sub>2</sub></small>SO<small><sub>3</sub></small>)." []
is_a: CHEBI:33482 ! sulfur oxoanion
is_a: CHEBI:48154 ! sulfur oxide
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:17137 ! is deprotonated form of hydrogensulfite

[Term]
id: CHEBI:17361
name: cytidine 5'-monophosphate
def: "A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23521 ! cytidine 5'-phosphate
is_a: CHEBI:39457 ! pyrimidine ribonucleoside 5'-monophosphate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:60377 ! is protonated form of cytidine 5'-monophosphate(2-)

[Term]
id: CHEBI:17362
name: quinoline
def: "The simplest member of the quinoline class of compounds, comprising a benzene ring <em>ortho</em> fused to C-2 and C-3 of a pyridine ring." []
synonym: "Quinoline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent
is_a: CHEBI:50893 ! azaarene
is_a: CHEBI:52362 ! ortho-fused heteroarene

[Term]
id: CHEBI:17364
name: D-aspartic acid
def: "The <small>D</small>-enantiomer of aspartic acid." []
synonym: "D-Aspartic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:22660 ! aspartic acid
is_a: CHEBI:22661 ! aspartic acid derivative
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:29990 ! is protonated form of D-aspartate(1-)
relationship: RO:0018039 CHEBI:17053 ! is enantiomer of L-aspartic acid

[Term]
id: CHEBI:17368
name: hypoxanthine
def: "A purine nucleobase that consists of purine bearing an oxo substituent at position 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25810 ! oxopurine
is_a: CHEBI:26386 ! purine nucleobase
is_a: CHEBI:67142 ! nucleobase analogue
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018038 CHEBI:16708 ! has functional parent adenine

[Term]
id: CHEBI:17375
name: (2S)-2-hydroxy monocarboxylic acid
def: "A 2-hydroxy monocarboxylic acid in which the carbon at position 2 has (<i>S</i>)-configuration." []
is_a: CHEBI:49302 ! 2-hydroxy monocarboxylic acid
relationship: RO:0018034 CHEBI:58123 ! is protonated form of (2S)-2-hydroxy monocarboxylic acid anion
relationship: RO:0018039 CHEBI:17893 ! is enantiomer of (2R)-2-hydroxy monocarboxylic acid

[Term]
id: CHEBI:17378
name: D-glyceraldehyde
def: "The <small>D</small>-enantiomer of glyceraldehyde." []
is_a: CHEBI:5445 ! glyceraldehyde
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018039 CHEBI:27975 ! is enantiomer of L-glyceraldehyde

[Term]
id: CHEBI:17418
name: valeric acid
def: "A straight-chain saturated fatty acid containing five carbon atoms." []
synonym: "Pentanoate" EXACT [KEGG_COMPOUND]
synonym: "PENTANOIC ACID" EXACT [PDBeChem]
synonym: "Pentanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26666 ! short-chain fatty acid
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:31011 ! is protonated form of valerate

[Term]
id: CHEBI:17431
name: agmatine
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:58145 ! is deprotonated form of agmatinium(2+)

[Term]
id: CHEBI:17433
name: queuine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38670 ! pyrrolopyrimidine
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:77674 ! is deprotonated form of queuine(1+)

[Term]
id: CHEBI:17441
name: chlorite
is_a: CHEBI:33437 ! chlorine oxoanion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:29219 ! is deprotonated form of chlorous acid

[Term]
id: CHEBI:17445
name: 3-hydroxyphenylacetic acid
def: "A monocarboxylic acid that is phenylacetic acid in which the hydrogen at position 3 on the benzene ring is replaced by a hydroxy group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:58149 ! is protonated form of 3-hydroxyphenylacetate
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:17447
name: geraniol
def: "A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24221 ! 3,7-dimethylocta-2,6-dien-1-ol
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:48318 ! has role fragrance
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:174690
name: clenbuterol
def: "A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(<em>tert</em>-butylamino)-1-hydroxyethyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50471 ! primary arylamine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0018033 CHEBI:61153 ! is deprotonated form of clenbuterol(1+)

[Term]
id: CHEBI:17478
name: aldehyde
def: "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." []
synonym: "Aldehyde" EXACT [KEGG_COMPOUND]
is_a: CHEBI:36586 ! carbonyl compound
relationship: BFO:0000051 CHEBI:42485 ! has part formyl group

[Term]
id: CHEBI:17489
name: 3',5'-cyclic AMP
def: "A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase." []
synonym: "Adenosine 3',5'-phosphate" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19834 ! 3',5'-cyclic purine nucleotide
is_a: CHEBI:61296 ! adenyl ribonucleotide
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:58165 ! is protonated form of 3',5'-cyclic AMP(1-)

[Term]
id: CHEBI:17497
name: glycolic acid
def: "A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated." []
synonym: "Hydroxyacetic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:49302 ! 2-hydroxy monocarboxylic acid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:50176 ! has role keratolytic drug
relationship: RO:0000087 CHEBI:64952 ! has role anti-HSV agent
relationship: RO:0018034 CHEBI:29805 ! is protonated form of glycolate
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:17499
name: hydrogen donor
def: "A molecular entity that can undergo oxidation by the loss of hydrogen atom(s)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23367 ! molecular entity
relationship: RO:0000087 CHEBI:15022 ! has role electron donor

[Term]
id: CHEBI:17514
name: cyanide
def: "A pseudohalide anion that is the conjugate base of hydrogen cyanide." []
synonym: "Cyanide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36828 ! pseudohalide anion
relationship: RO:0000087 CHEBI:38500 ! has role EC 1.9.3.1 (cytochrome c oxidase) inhibitor
relationship: RO:0018033 CHEBI:18407 ! is deprotonated form of hydrogen cyanide
relationship: RO:0018033 CHEBI:36856 ! is deprotonated form of hydrogen isocyanide

[Term]
id: CHEBI:17521
name: (-)-quinic acid
def: "The (−)-enantiomer of quinic acid." []
is_a: CHEBI:26493 ! quinic acid
relationship: RO:0018034 CHEBI:29751 ! is protonated form of (-)-quinate
relationship: RO:0018039 CHEBI:36124 ! is enantiomer of (+)-quinic acid

[Term]
id: CHEBI:17522
name: alditol
def: "A carbohydrate that is an acyclic polyol having the general formula HOCH<small><sub>2</sub></small>[CH(OH)]<small><sub><em>n</em></sub></small>CH<small><sub>2</sub></small>OH (formally derivable from an aldose by reduction of the carbonyl group)." []
is_a: CHEBI:16646 ! carbohydrate
is_a: CHEBI:26191 ! polyol

[Term]
id: CHEBI:17544
name: hydrogencarbonate
def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." []
synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35604 ! carbon oxoanion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28976 ! is deprotonated form of carbonic acid
relationship: RO:0018034 CHEBI:41609 ! is protonated form of carbonate

[Term]
id: CHEBI:17549
name: 5-aminolevulinic acid
def: "The simplest δ-amino acid in which the hydrogens at the γ position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp." []
synonym: "5-Amino-4-oxopentanoate" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35931 ! delta-amino acid
is_a: CHEBI:35950 ! 4-oxo monocarboxylic acid
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:132970 ! is deprotonated form of 5-ammoniolevulinic acid
relationship: RO:0018034 CHEBI:12109 ! is protonated form of 5-aminolevulinate
relationship: RO:0018036 CHEBI:356416 ! is tautomer of 5-ammoniolevulinate
relationship: RO:0018038 CHEBI:35931 ! has functional parent delta-amino acid
relationship: RO:0018038 CHEBI:45630 ! has functional parent 4-oxopentanoic acid

[Term]
id: CHEBI:17561
name: L-cysteine
def: "An optically active form of cysteine having <small>L</small>-configuration." []
synonym: "CYSTEINE" EXACT [PDBeChem]
synonym: "L-Cysteine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:15356 ! cysteine
is_a: CHEBI:15705 ! L-alpha-amino acid
is_a: CHEBI:26650 ! serine family amino acid
is_a: CHEBI:83813 ! proteinogenic amino acid
relationship: RO:0000087 CHEBI:64577 ! has role flour treatment agent
relationship: RO:0000087 CHEBI:77703 ! has role EC 4.3.1.3 (histidine ammonia-lyase) inhibitor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32445 ! is deprotonated form of L-cysteinium
relationship: RO:0018034 CHEBI:32442 ! is protonated form of L-cysteinate(1-)
relationship: RO:0018036 CHEBI:35235 ! is tautomer of L-cysteine zwitterion
relationship: RO:0018039 CHEBI:16375 ! is enantiomer of D-cysteine

[Term]
id: CHEBI:17563
name: phthalate(2-)
def: "A phthalate that is the dianion obtained by the deprotonation of both the carboxy groups of phthalic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26092 ! phthalate
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:30800 ! is deprotonated form of phthalate(1-)

[Term]
id: CHEBI:17568
name: uracil
def: "A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription." []
is_a: CHEBI:26432 ! pyrimidine nucleobase
is_a: CHEBI:38337 ! pyrimidone
is_a: CHEBI:38387 ! 9,11,15-octadecatrienoic acid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018036 CHEBI:43254 ! is tautomer of (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one

[Term]
id: CHEBI:17573
name: glycyrrhetinate
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:30853 ! is deprotonated form of glycyrrhetinic acid

[Term]
id: CHEBI:17578
name: toluene
def: "The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent." []
synonym: "TOLUENE" EXACT [PDBeChem]
synonym: "Toluene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:38975 ! methylbenzene
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:48873 ! has role cholinergic antagonist
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:62803 ! has role fuel additive

[Term]
id: CHEBI:175787
name: Fucosyllactose
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:17579
name: beta-carotene
def: "A cyclic carotene obtained by dimerisation of <i>all</i>-<i>trans</i>-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:139120 ! carotenoid beta-end derivative
is_a: CHEBI:35163 ! cyclic carotene
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:26130 ! has role biological pigment
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67200 ! has role provitamin A
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:17590
name: octane
def: "A straight chain alkane composed of 8 carbon atoms." []
synonym: "Octane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic

[Term]
id: CHEBI:175901
name: gemcitabine
def: "A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer." []
synonym: "2'-Deoxy-2',2'-difluorocytidine" EXACT [ChemIDplus]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:132992 ! has role radiosensitizing agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:74213 ! has role EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:17593
name: maltooligosaccharide
def: "A glucooligosaccharide derived from glucose monomers linked via α-<small>D</small>-1,4 bonds as in maltose.  The term is commonly applied to the series of linear oligosaccharides composed of two, three, four, five and six such units of glucose." []
is_a: CHEBI:24268 ! glucooligosaccharide

[Term]
id: CHEBI:17594
name: hydroquinone
def: "A benzenediol comprising benzene core carrying two hydroxy substituents <em>para</em> to each other." []
synonym: "Benzene-1,4-diol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17701 ! benzenediol
is_a: CHEBI:24646 ! hydroquinones
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:85046 ! has role skin lightening agent

[Term]
id: CHEBI:17596
name: inosine
def: "A purine nucleoside in which hypoxanthine is attached to ribofuranose via a β-<em>N</em><small><sup>9</small></sup>-glycosidic bond." []
synonym: "INOSINE" EXACT [PDBeChem]
synonym: "Inosine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:142355 ! purines D-ribonucleoside
is_a: CHEBI:24844 ! inosines
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018038 CHEBI:17368 ! has functional parent hypoxanthine

[Term]
id: CHEBI:17602
name: 4-aminophenol
def: "An amino phenol (one of the three possible isomers) which has the single amino substituent located <em>para</em> to the phenolic -OH group." []
synonym: "4-AMINOPHENOL" EXACT [PDBeChem]
synonym: "4-Aminophenol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:28829 ! aminophenol
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:17608
name: D-aldohexose
def: "Any <small>D</small>-aldose having a chain of six carbon atoms in the molecule." []
is_a: CHEBI:33917 ! aldohexose
is_a: CHEBI:4194 ! D-hexose

[Term]
id: CHEBI:17612
name: (3,4-dihydroxyphenyl)acetate
def: "A dihydroxy monocarboxylic acid anion that is the conjugate base of (3,4-dihydroxyphenyl)acetic acid, arising from deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:41941 ! is deprotonated form of (3,4-dihydroxyphenyl)acetic acid
relationship: RO:0018038 CHEBI:18401 ! has functional parent phenylacetate

[Term]
id: CHEBI:17620
name: trans-ferulic acid
def: "A ferulic acid consisting of <i>trans</i>-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring." []
is_a: CHEBI:193350 ! ferulic acid
relationship: RO:0000087 CHEBI:64345 ! has role MALDI matrix material
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:77307 ! has role cardioprotective agent
relationship: RO:0018034 CHEBI:29749 ! is protonated form of trans-ferulate

[Term]
id: CHEBI:17623
name: cyclomaltodextrin
def: "A cyclic oligosaccharide comprising a ring of <small>D</small>-glucose units linked by α-(1→4) glycosidic bonds." []
is_a: CHEBI:23448 ! cyclic oligosaccharide
is_a: CHEBI:25140 ! maltodextrin

[Term]
id: CHEBI:17632
name: nitrate
def: "A nitrogen oxoanion formed by loss of a proton from nitric acid. Principal species present at pH 7.3." []
synonym: "nitrate" EXACT [UniProt]
is_a: CHEBI:33458 ! nitrogen oxoanion
is_a: CHEBI:62764 ! reactive nitrogen species
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:48107 ! is deprotonated form of nitric acid

[Term]
id: CHEBI:17634
name: D-glucose
def: "A glucose with <small>D</small>-configuration." []
is_a: CHEBI:17234 ! glucose
is_a: CHEBI:17608 ! D-aldohexose

[Term]
id: CHEBI:17642
name: pentachlorophenol
def: "A  chlorophenol that is phenol substituted by 5 chloro groups." []
synonym: "PENTACHLOROPHENOL" EXACT [PDBeChem]
synonym: "Pentachlorophenol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23150 ! chlorophenol
is_a: CHEBI:38656 ! organochlorine pesticide
is_a: CHEBI:83390 ! pentachlorobenzenes
is_a: CHEBI:87034 ! aromatic fungicide
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:58217 ! is protonated form of pentachlorophenolate
relationship: RO:0018038 CHEBI:47136 ! has functional parent pentachlorobenzene

[Term]
id: CHEBI:176497
name: geroprotector
def: "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:17650
name: cortisol
def: "A 17α-hydroxy-C<small><sub>21</sub></small>-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the \"stress hormone\" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses." []
is_a: CHEBI:138141 ! 17alpha-hydroxy-C21-steroid
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:49167 ! has role anti-asthmatic drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64952 ! has role anti-HSV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:176510
name: 2-amino-4-(S-butylsulfonimidoyl)butanoic acid
def: "A non-proteinogenic α-amino acid that is homocysteine in which the thiol group carries an oxo, imino and butyl groups." []
is_a: CHEBI:24610 ! homocysteines
is_a: CHEBI:38084 ! sulfoximide

[Term]
id: CHEBI:17654
name: electron acceptor
def: "A substance to which an electron may be transferred." []
is_a: CHEBI:15339 ! acceptor

[Term]
id: CHEBI:17658
name: tylosin
def: "A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. It is found naturally as a fermentation product of <em>Streptomyces fradiae</em>." []
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:25022 ! leucomycin
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:28963 ! amino sugar
is_a: CHEBI:51689 ! enone
is_a: CHEBI:63353 ! disaccharide derivative
is_a: CHEBI:63367 ! monosaccharide derivative
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:77047 ! is deprotonated form of tylosin(1+)
relationship: RO:0018038 CHEBI:29700 ! has functional parent tylactone

[Term]
id: CHEBI:17668
name: ribonucleoside diphosphat
is_a: CHEBI:16862 ! nucleoside 5'-diphosphate

[Term]
id: CHEBI:176783
name: vitamin C
def: "Any member of a group of vitamers that belong to the chemical structural class called butenolides that exhibit biological activity against vitamin C deficiency in animals. The vitamers include <small>L</small>-ascorbic acid and its salt, ionized and oxidized forms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50523 ! butenolide
relationship: RO:0000087 CHEBI:27314 ! has role water-soluble vitamin (role)

[Term]
id: CHEBI:176838
name: vitamin B2
def: "Any member of a group of vitamers that belong to the chemical structural class called flavins that exhibit biological activity against vitamin B<small><sub>2</sub></small> deficiency. Symptoms associated with vitamin B<small><sub>2</sub></small> deficiency include glossitis, seborrhea, angular stomaitis, cheilosis and photophobia. The vitamers include riboflavin and its phosphate derivatives (and includes their salt, ionised and hydrate forms)." []
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:176839
name: vitamin B3
def: "Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B<small><sub>3</sub></small> deficiency. Vitamin B<small><sub>3</sub></small> deficiency causes a condition known as <a href=\"https://en.wikipedia.org/wiki/Pellagra\" target=\"_blank\">pellagra</a> whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms)." []
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:176840
name: vitamin B5
def: "Any member of a group of vitamers that belong to the chemical structural class called pantothenic acids that exhibit biological activity against vitamin B<small><sub>5</sub></small> deficiency. Deficiency of vitamin B<small><sub>5</sub></small> is rare due to its widespread distribution in whole grain cereals, legumes and meat. Symptoms associated with vitamin B<small><sub>5</sub></small> deficiency are difficult to asses since they are subtle and resemble those of other B vitamin deficiencies. The vitamers include (<i>R</i>)-pantothenic acid and its ionized and salt forms." []
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:176841
name: vitamin B7
def: "Any member of a group of vitamers that belong to the chemical structural class called biotins that exhibit biological activity against vitamin B<small><sub>7</sub></small> deficiency. Vitamin B<small><sub>7</sub></small> deficiency is very rare in individuals who take a normal balanced diet. Foods rich in biotin are egg yolk, liver, cereals, vegetables (spinach, mushrooms) and rice. Symptoms associated with vitamin B<small><sub>7</sub></small> deficiency include thinning hair, scaly skin rashes around eyes, nose and mouth, and brittle nails. The vitamers include biotin and its ionized and salt forms." []
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:176842
name: vitamin B9
def: "Any B-vitamin that exhibits biological activity against vitamin B<small><sub>9</sub></small> deficiency. Vitamin B<small><sub>9</sub></small> refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B<small><sub>9</sub></small> leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B<small><sub>9</sub></small> deficiency include fatigue, muscle weakness, and pale skin." []
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:176843
name: vitamin B12
def: "Any member of a group of cobalamin vitamers that exhibit biological activity against vitamin B<small><sub>12</sub></small> deficiency. Vitamin B<small><sub>12</sub></small> deficiency is associated with low red blood cell count and anemia. The vitamers are found in foods such as cereals, meat, fish, and poultry. The vitamers include adenosylcobalamin, hydroxocobalamin, cyanocobalamin, aquacobalamin, nitritocobalamin and methylcobabalamin (also includes their ionized, salt and phosphate derivatives)." []
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:17688
name: (S)-nicotine
def: "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has <i>S</i>-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from <em>Nicotiana tabacum</em>." []
is_a: CHEBI:138000 ! 3-(1-methylpyrrolidin-2-yl)pyridine
relationship: RO:0000087 CHEBI:22917 ! has role phytogenic insecticide
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:47958 ! has role nicotinic acetylcholine receptor agonist
relationship: RO:0000087 CHEBI:49110 ! has role peripheral nervous system drug
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:52290 ! has role mitogen
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:59806 ! is deprotonated form of (S)-nicotinium(1+)
relationship: RO:0018039 CHEBI:39162 ! is enantiomer of (R)-nicotine

[Term]
id: CHEBI:176975
name: KP1339
def: "A ruthenium coordination entity that is the sodium salt of tetrachloro[bis(1<em>H</em>-indazole)]ruthenate(III). It is a anticancer drug in clinical development for the treatment of solid tumours." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35733 ! ruthenium coordination entity
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:17698
name: chloramphenicol
def: "An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23824 ! diol
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37622 ! carboxamide
relationship: RO:0000087 CHEBI:131604 ! has role Mycoplasma genitalium metabolite
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:17701
name: benzenediol
synonym: "Benzenediol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33570 ! benzenediols

[Term]
id: CHEBI:17710
name: (R)-mevalonic acid
def: "The (<i>R</i>)-enantiomer of mevalonic acid." []
is_a: CHEBI:194519 ! 3,5-dihydroxy-3-methylpentanoic acid
relationship: RO:0018034 CHEBI:36464 ! is protonated form of (R)-mevalonate
relationship: RO:0018039 CHEBI:28880 ! is enantiomer of (S)-mevalonic acid

[Term]
id: CHEBI:17716
name: lactose
def: "A glycosylglucose disaccharide, found most notably in milk, that consists of <small>D</small>-galactose and <small>D</small>-glucose fragments bonded through a β-1→4 glycosidic linkage. The glucose fragment can be in either the α- or β-pyranose form, whereas the galactose fragment can only have the β-pyranose form." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24405 ! glycosylglucose
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:177333
name: organic tetracyclic compound
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:177387
name: brequinar
def: "A quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for <em>de novo</em> pyrimidine biosynthesis. The compound exhibits antineoplastic and antiviral properties." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:26512 ! quinolinemonocarboxylic acid
is_a: CHEBI:83575 ! monofluorobenzenes
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:68543 ! has role pyrimidine synthesis inhibitor
relationship: RO:0000087 CHEBI:77103 ! has role EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor
relationship: RO:0018034 CHEBI:177870 ! is protonated form of brequinar(1-)

[Term]
id: CHEBI:17741
name: N,N-dimethylformamide
def: "A member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups." []
synonym: "N,N-Dimethylformamide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:24079 ! formamides
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0018038 CHEBI:16397 ! has functional parent formamide

[Term]
id: CHEBI:17747
name: bis(2-ethylhexyl) phthalate
def: "A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid." []
is_a: CHEBI:35484 ! phthalate ester
is_a: CHEBI:51307 ! diester
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:77326 ! has role androstane receptor agonist
relationship: RO:0000087 CHEBI:79056 ! has role plasticiser

[Term]
id: CHEBI:17748
name: thymidine
def: "A pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase." []
synonym: "THYMIDINE" EXACT [PDBeChem]
synonym: "Thymidine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018038 CHEBI:17821 ! has functional parent thymine
relationship: RO:0018039 CHEBI:63624 ! is enantiomer of telbivudine

[Term]
id: CHEBI:17754
name: glycerol
def: "A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17522 ! alditol
is_a: CHEBI:27136 ! triol
is_a: CHEBI:35681 ! secondary alcohol
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:25728 ! has role osmolyte
relationship: RO:0000087 CHEBI:27780 ! has role detergent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite

[Term]
id: CHEBI:17761
name: ceramide
def: "Ceramides (<em>N</em>-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R<small><sup>1</small></sup> = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H." []
is_a: CHEBI:26739 ! sphingolipid
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:177719
name: Avasimibe
is_a: CHEBI:25409 ! monoterpenoid

[Term]
id: CHEBI:177763
name: Diallyltetrasulfane
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:17781
name: lumichrome
def: "A compound showing blue fluorescence, formed by a photolysis of riboflavin in acid or neutral solution." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37324 ! 7,8-dimethylbenzo[g]pteridine-2,4-dione
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018036 CHEBI:37323 ! is tautomer of 7,8-dimethylisoalloxazine
relationship: RO:0018038 CHEBI:37325 ! has functional parent alloxazine

[Term]
id: CHEBI:177870
name: brequinar(1-)
def: "A quinolinemonocarboxylate that is the conjugate base of brequinar arising from the deprotonation of the carboxy group. Major microspecies at pH 7.3." []
is_a: CHEBI:38773 ! quinolinemonocarboxylate
relationship: RO:0018033 CHEBI:177387 ! is deprotonated form of brequinar

[Term]
id: CHEBI:17790
name: methanol
def: "The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group." []
synonym: "METHANOL" EXACT [PDBeChem]
synonym: "Methanol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:26191 ! polyol
is_a: CHEBI:50584 ! alkyl alcohol
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:131604 ! has role Mycoplasma genitalium metabolite
relationship: RO:0000087 CHEBI:33292 ! has role fuel
relationship: RO:0000087 CHEBI:48360 ! has role amphiprotic solvent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:52090 ! is protonated form of methoxide

[Term]
id: CHEBI:177917
name: phenolic steroid
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:36834 ! 3-hydroxy steroid

[Term]
id: CHEBI:17792
name: organohalogen compound
def: "A compound containing at least one carbon-halogen bond (where X is a halogen atom)." []
is_a: CHEBI:33285 ! heteroorganic entity
is_a: CHEBI:37578 ! halide

[Term]
id: CHEBI:17814
name: salicin
def: "An aryl β-<small>D</small>-glucoside that is salicyl alcohol in which the phenolic hydrogen has been replaced by a β-<small>D</small>-glucosyl residue." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22743 ! benzyl alcohols
is_a: CHEBI:28749 ! aryl beta-D-glucoside
is_a: CHEBI:33857 ! aromatic primary alcohol
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35544 ! has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0018038 CHEBI:16464 ! has functional parent salicyl alcohol

[Term]
id: CHEBI:17821
name: thymine
def: "A pyrimidine nucleobase that is uracil in which the hydrogen at position 5 is replaced by a methyl group." []
synonym: "THYMINE" EXACT [PDBeChem]
synonym: "Thymine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26432 ! pyrimidine nucleobase
is_a: CHEBI:38337 ! pyrimidone
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:17822
name: serine
def: "An α-amino acid that is alanine substituted at position 3 by a hydroxy group." []
synonym: "Serine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:24712 ! has part hydroxymethyl group
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32846 ! is deprotonated form of serinium
relationship: RO:0018034 CHEBI:32845 ! is protonated form of serinate
relationship: RO:0018036 CHEBI:35243 ! is tautomer of serine zwitterion

[Term]
id: CHEBI:17824
name: propan-2-ol
def: "A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group." []
synonym: "Propan-2-ol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:167095 ! secondary fatty alcohol
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:17833
name: gentamycin
def: "Any of a group of aminoglycoside antibiotics produced by fermentation of some <em>Micromonospora</em> spp." []
is_a: CHEBI:22479 ! amino cyclitol glycoside
is_a: CHEBI:22507 ! aminoglycoside antibiotic

[Term]
id: CHEBI:1784
name: biphenyl-4-amine
def: "An aminobiphenyl that is biphenyl substituted by an amino group at position 4." []
is_a: CHEBI:22496 ! aminobiphenyl
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018040 CHEBI:17097 ! has parent hydride biphenyl

[Term]
id: CHEBI:17840
name: indoxyl
def: "A member of the class of hydroxyindoles that is 1<em>H</em>-indole substituted by a hydroxy group at position 3." []
synonym: "1H-indol-3-ol" EXACT [ChEBI]
is_a: CHEBI:74818 ! heteroaryl hydroxy compound
is_a: CHEBI:84729 ! hydroxyindoles

[Term]
id: CHEBI:17847
name: p-cresol
def: "A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals." []
is_a: CHEBI:25399 ! cresol
relationship: RO:0000087 CHEBI:64584 ! has role uremic toxin
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:17854
name: cyclohexanone
def: "A cyclic ketone that consists of cyclohexane bearing a single oxo substituent." []
synonym: "CYCLOHEXANONE" EXACT [PDBeChem]
synonym: "Cyclohexanone" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23482 ! cyclohexanones
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite

[Term]
id: CHEBI:17855
name: triglyceride
def: "Any glyceride resulting from the condensation of all three hydroxy groups of glycerol (propane-1,2,3-triol) with fatty acids." []
is_a: CHEBI:47778 ! glyceride
is_a: CHEBI:76579 ! triradylglycerol

[Term]
id: CHEBI:17858
name: glutathione disulfide
is_a: CHEBI:24337 ! glutathione derivative
is_a: CHEBI:25676 ! oligopeptide
is_a: CHEBI:35489 ! organic disulfide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:58297 ! is protonated form of glutathione disulfide(2-)

[Term]
id: CHEBI:17859
name: glutaric acid
def: "An α,ω-dicarboxylic acid that is a linear five-carbon dicarboxylic acid." []
synonym: "Pentanedioic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:189840 ! dicarboxylic fatty acid
is_a: CHEBI:28383 ! alpha,omega-dicarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018034 CHEBI:35907 ! is protonated form of glutarate(1-)

[Term]
id: CHEBI:17865
name: 4-methyl-2-oxopentanoate
def: "A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:191201 ! branched-chain keto acid anion
is_a: CHEBI:35179 ! 2-oxo monocarboxylic acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:48430 ! is deprotonated form of 4-methyl-2-oxopentanoic acid
relationship: RO:0018038 CHEBI:31011 ! has functional parent valerate

[Term]
id: CHEBI:17879
name: 4-hydroxybenzoate
def: "The conjugate base of 4-hydroxybenzoic acid, comprising a 4-hydroxybenzoic acid core with a proton missing to give a charge of -1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25388 ! monohydroxybenzoate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:30763 ! is deprotonated form of 4-hydroxybenzoic acid
relationship: RO:0018038 CHEBI:16150 ! has functional parent benzoate

[Term]
id: CHEBI:17883
name: hydrogen chloride
def: "A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms." []
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18140 ! hydrogen halide
is_a: CHEBI:23117 ! chlorine molecular entity
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:50315 ! is deprotonated form of chloronium
relationship: RO:0018034 CHEBI:17996 ! is protonated form of chloride

[Term]
id: CHEBI:17890
name: tryptophol
def: "An indolyl alcohol that is ethanol substituted by a 1<em>H</em>-indol-3-yl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38467 ! indolyl alcohol
relationship: RO:0000087 CHEBI:22676 ! has role auxin
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:17891
name: donor
def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:17893
name: (2R)-2-hydroxy monocarboxylic acid
def: "A 2-hydroxy monocarboxylic acid having (2<i>R</i>)-configuration." []
is_a: CHEBI:49302 ! 2-hydroxy monocarboxylic acid
relationship: RO:0018034 CHEBI:58314 ! is protonated form of (2R)-2-hydroxy monocarboxylic acid anion
relationship: RO:0018039 CHEBI:17375 ! is enantiomer of (2S)-2-hydroxy monocarboxylic acid

[Term]
id: CHEBI:17895
name: L-tyrosine
def: "An optically active form of tyrosine having <small>L</small>-configuration." []
synonym: "L-Tyrosine" EXACT [KEGG_COMPOUND]
synonym: "TYROSINE" EXACT [PDBeChem]
is_a: CHEBI:18186 ! tyrosine
is_a: CHEBI:73690 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:64416 ! has role EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32762 ! is deprotonated form of L-tyrosinium
relationship: RO:0018034 CHEBI:32760 ! is protonated form of L-tyrosinate(1-)
relationship: RO:0018036 CHEBI:58315 ! is tautomer of L-tyrosine zwitterion
relationship: RO:0018038 CHEBI:46209 ! has functional parent L-tyrosinal
relationship: RO:0018039 CHEBI:28479 ! is enantiomer of D-tyrosine

[Term]
id: CHEBI:17898
name: all-trans-retinal
def: "A retinal in which all four exocyclic double bonds have <i>E</i>- (<i>trans</i>-) geometry." []
is_a: CHEBI:12777 ! vitamin A
is_a: CHEBI:15035 ! retinal
relationship: RO:0000087 CHEBI:67195 ! has role gap junctional intercellular communication inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:17907
name: styrene oxide
def: "An epoxide that is oxirane in which one of the hydrogens has been replaced by a phenyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32955 ! epoxide
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018040 CHEBI:27452 ! has parent hydride styrene

[Term]
id: CHEBI:17920
name: 3-methyleneoxindole
is_a: CHEBI:38459 ! oxindoles

[Term]
id: CHEBI:17963
name: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
def: "A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4." []
synonym: "1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25340 ! methylpyridines
is_a: CHEBI:26921 ! tetrahydropyridine
is_a: CHEBI:38193 ! phenylpyridine
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:17967
name: urethane
def: "A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages." []
synonym: "Ethyl carbamate" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite

[Term]
id: CHEBI:17968
name: butyrate
def: "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:78115 ! fatty acid anion 4:0
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30772 ! is deprotonated form of butyric acid

[Term]
id: CHEBI:17972
name: ribonucleoside triphosphate
is_a: CHEBI:17326 ! nucleoside 5'-triphoshate

[Term]
id: CHEBI:17987
name: benzyl alcohol
def: "An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent." []
synonym: "Phenylmethanol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22743 ! benzyl alcohols
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:48318 ! has role fragrance

[Term]
id: CHEBI:17992
name: sucrose
def: "A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24407 ! glycosyl glycoside
is_a: CHEBI:59777 ! ketal
relationship: RO:0000087 CHEBI:25728 ! has role osmolyte
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite

[Term]
id: CHEBI:17996
name: chloride
def: "A halide anion formed when chlorine picks up an electron to form an an anion." []
synonym: "Chloride" EXACT [KEGG_COMPOUND]
synonym: "chloride" EXACT [UniProt]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:16042 ! halide anion
is_a: CHEBI:33432 ! monoatomic chlorine
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17883 ! is deprotonated form of hydrogen chloride

[Term]
id: CHEBI:17997
name: dinitrogen
def: "An elemental molecule consisting of two trivalently-bonded nitrogen atoms." []
synonym: "Nitrogen" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:25362 ! elemental molecule
is_a: CHEBI:33266 ! diatomic nitrogen
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas
relationship: RO:0000087 CHEBI:78017 ! has role food propellant
relationship: RO:0018033 CHEBI:30102 ! is deprotonated form of diazynium

[Term]
id: CHEBI:18010
name: 3',4',5-trihydroxy-3,7-dimethoxyflavone
def: "A dimethoxyflavone that the 3,7-di-<em>O</em>-methyl derivative of quercetin." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23798 ! dimethoxyflavone
is_a: CHEBI:27116 ! trihydroxyflavone
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:50781 ! has role EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
relationship: RO:0018034 CHEBI:77710 ! is protonated form of 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-)
relationship: RO:0018038 CHEBI:16243 ! has functional parent quercetin

[Term]
id: CHEBI:18012
name: fumaric acid
def: "A butenedioic acid in which the C=C double bond has <i>E</i> geometry. It is an intermediate metabolite in the citric acid cycle." []
is_a: CHEBI:22958 ! butenedioic acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:37154 ! is protonated form of fumarate(1-)

[Term]
id: CHEBI:18019
name: L-lysine
def: "An <small>L</small>-α-amino acid; the <small>L</small>-isomer of lysine." []
synonym: "L-Lysine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22658 ! aspartate family amino acid
is_a: CHEBI:25094 ! lysine
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32551 ! is deprotonated form of L-lysinium(1+)
relationship: RO:0018034 CHEBI:32550 ! is protonated form of L-lysinate
relationship: RO:0018036 CHEBI:133538 ! is tautomer of L-lysine zwitterion
relationship: RO:0018039 CHEBI:16855 ! is enantiomer of D-lysine

[Term]
id: CHEBI:18022
name: thiocyanate
def: "A pseudohalide anion obtained by deprotonation of the thiol group of thiocyanic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:36828 ! pseudohalide anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:24928 ! is deprotonated form of isothiocyanic acid
relationship: RO:0018033 CHEBI:29200 ! is deprotonated form of thiocyanic acid

[Term]
id: CHEBI:18044
name: dialkyl ketone
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:180482
name: 1,2,4-triazole-3-carboxamide
def: "A member of the class of triazoles that is 1<em>H</em>-1,2,4-triazole substituted by an aminocarbonyl group at position 3. It is the major catabolite and aglycon of ribavirin." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140324 ! primary carboxamide
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite

[Term]
id: CHEBI:18049
name: piperidine
def: "An azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine." []
synonym: "Piperidine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:37949 ! azacycloalkane
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:35223 ! has role catalyst
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:589779 ! is deprotonated form of piperidinium

[Term]
id: CHEBI:18050
name: L-glutamine
def: "An optically active form of glutamine having <small>L</small>-configuration." []
synonym: "GLUTAMINE" EXACT [PDBeChem]
synonym: "L-Glutamine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24318 ! glutamine family amino acid
is_a: CHEBI:28300 ! glutamine
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:61908 ! has role EC 1.14.13.39 (nitric oxide synthase) inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32666 ! is deprotonated form of L-glutaminium
relationship: RO:0018034 CHEBI:32665 ! is protonated form of L-glutaminate
relationship: RO:0018036 CHEBI:58359 ! is tautomer of L-glutamine zwitterion
relationship: RO:0018039 CHEBI:17061 ! is enantiomer of D-glutamine

[Term]
id: CHEBI:18053
name: 1-aminocyclopropanecarboxylic acid
def: "A non-proteinogenic α-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position." []
synonym: "1-Aminocyclopropane-1-carboxylic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0000087 CHEBI:24002 ! has role ethylene releasers
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:30526 ! is protonated form of 1-aminocyclopropanecarboxylate
relationship: RO:0018036 CHEBI:58360 ! is tautomer of 1-aminocyclopropanecarboxylic acid zwitterion
relationship: RO:0018038 CHEBI:23500 ! has functional parent cyclopropanecarboxylic acid

[Term]
id: CHEBI:18059
name: lipid
def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:18067
name: phylloquinone
def: "A member of the class of phylloquinones that consists of 1,4-naphthoquinone having methyl and phytyl groups at positions 2 and 3 respectively. The parent of the class of phylloquinones." []
is_a: CHEBI:26106 ! phylloquinones
is_a: CHEBI:28384 ! vitamin K
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:180683
name: lignocellulose
def: "A complex biopolymer that is a component of plant cell walls which is used as a renewable feedstock for the production of paper, fuels, and chemicals (also used as a feed supplement in the poultry industry). Its structure comprises of three main types of carbon-based polymer — cellulose, hemicellulose and lignin. Generally, its biomass consists of 35-50% cellulose, 20-35% hemicellulose, and 10-25% lignin with proteins, oils, and ash making up the remaining fraction." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33694 ! biomacromolecule
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:18246 ! has part (1->4)-beta-D-glucan
relationship: BFO:0000051 CHEBI:61266 ! has part hemicellulose
relationship: BFO:0000051 CHEBI:6457 ! has part lignin
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical

[Term]
id: CHEBI:180694
name: fasudil(1+)
def: "A secondary ammonium ion that is the conjugate acid of fasudil arising from the protonation of the diazepane ring; major species at pH 7.3." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:43871 ! is protonated form of fasudil

[Term]
id: CHEBI:18085
name: glycosaminoglycan
def: "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." []
synonym: "Glycosaminoglycan" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22506 ! aminoglycan

[Term]
id: CHEBI:18088
name: formononetin
def: "A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133959 ! 4'-methoxyisoflavones
is_a: CHEBI:55465 ! 7-hydroxyisoflavones
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76989 ! has role phytoestrogen
relationship: RO:0018034 CHEBI:77688 ! is protonated form of formononetin(1-)
relationship: RO:0018038 CHEBI:28197 ! has functional parent daidzein

[Term]
id: CHEBI:180904
name: (R)-nicardipine
def: "The <i>R</i>-enantiomer of nicardipine." []
is_a: CHEBI:180905 ! 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0018039 CHEBI:135777 ! is enantiomer of (S)-nicardipine

[Term]
id: CHEBI:180905
name: 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
def: "A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:50075 ! dihydropyridine
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:51307 ! diester

[Term]
id: CHEBI:180911
name: suramin(6-)
def: "An organosulfate oxoanion that is the hexanion of suramin resulting from the deprotonation of the six sulfo groups; major species at pH 7.3." []
is_a: CHEBI:58958 ! organosulfate oxoanion
relationship: RO:0018033 CHEBI:45906 ! is deprotonated form of suramin

[Term]
id: CHEBI:18099
name: cyclohexanol
def: "An alcohol that consists of cyclohexane bearing a single hydroxy substituent. The parent of the class of cyclohexanols." []
synonym: "Cyclohexanol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23480 ! cyclohexanols
is_a: CHEBI:35681 ! secondary alcohol
relationship: RO:0000087 CHEBI:46787 ! has role solvent

[Term]
id: CHEBI:18101
name: 4-hydroxyphenylacetic acid
def: "A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:48999 ! is protonated form of 4-hydroxyphenylacetate
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:18127
name: cadaverine
def: "An alkane-α,ω-diamine comprising a straight-chain pentane core with amino substitutents at positions 1 and 5. A colourless syrupy liquid diamine with a distinctive unpleasant odour, it is a homologue of putresceine and is formed by the bacterial decarboxylation of lysine that occurs during protein hydrolysis during putrefaction of animal tissue. It is also found in plants such as soyabean." []
synonym: "PENTANE-1,5-DIAMINE" EXACT [PDBeChem]
is_a: CHEBI:35411 ! alkane-alpha,omega-diamine
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:58384 ! is deprotonated form of cadaverine(2+)

[Term]
id: CHEBI:18133
name: hexose
def: "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." []
is_a: CHEBI:35381 ! monosaccharide

[Term]
id: CHEBI:18135
name: catechol
def: "A  benzenediol comprising of a benzene core carrying two hydroxy substituents <em>ortho </em> to each other." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33566 ! catechols
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:62215 ! has role allelochemical
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:50524 ! is protonated form of catecholate(1-)

[Term]
id: CHEBI:18139
name: trimethylamine
def: "A tertiary amine that is ammonia in which each hydrogen atom is substituted by an methyl group." []
synonym: "N,N-Dimethylmethanamine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25274 ! methylamines
is_a: CHEBI:32876 ! tertiary amine
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:58389 ! is deprotonated form of trimethylammonium

[Term]
id: CHEBI:18140
name: hydrogen halide
synonym: "hydrogen halides" EXACT [ChEBI]
is_a: CHEBI:33405 ! hydracid
relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid

[Term]
id: CHEBI:18145
name: (R,R,R)-alpha-tocopherol
def: "An α-tocopherol that has <i>R</i>,<i>R</i>,<i>R</i> configuration. The naturally occurring stereoisomer of α-tocopherol, it is found particularly in sunflower and olive oils." []
is_a: CHEBI:22470 ! alpha-tocopherol
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:37700 ! has role EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:50855 ! has role antiatherogenic agent
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018039 CHEBI:46430 ! is enantiomer of (S,S,S)-alpha-tocopherol

[Term]
id: CHEBI:18152
name: myricetin
def: "A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of <em>Myrica rubra</em> and other plants." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24561 ! hexahydroxyflavone
is_a: CHEBI:52267 ! 7-hydroxyflavonol
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50630 ! has role cyclooxygenase 1 inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78295 ! has role food component
relationship: RO:0018034 CHEBI:58395 ! is protonated form of myricetin(1-)

[Term]
id: CHEBI:18153
name: ethene
synonym: "Ethylene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:32878 ! alkene
relationship: RO:0000087 CHEBI:37848 ! has role plant hormone
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:18154
name: polysaccharide
def: "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." []
is_a: CHEBI:16646 ! carbohydrate
is_a: CHEBI:167559 ! glycan
is_a: CHEBI:33694 ! biomacromolecule

[Term]
id: CHEBI:18172
name: fluoroacetate
def: "A haloacetate(1−) resulting from the deprotonation of the carboxy group of fluoroacetic acid." []
is_a: CHEBI:85638 ! haloacetate(1-)
relationship: RO:0018033 CHEBI:30775 ! is deprotonated form of fluoroacetic acid

[Term]
id: CHEBI:18186
name: tyrosine
def: "An α-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring." []
synonym: "Tyrosine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:33856 ! aromatic amino acid
relationship: BFO:0000051 CHEBI:50336 ! has part 4-hydroxybenzyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32786 ! is deprotonated form of tyrosinium
relationship: RO:0018034 CHEBI:32784 ! is protonated form of tyrosinate(1-)
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:18208
name: benzylpenicillin
def: "A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group." []
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:88187 ! penicillin allergen
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:53000 ! has role epitope
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:51354 ! is protonated form of benzylpenicillin(1-)

[Term]
id: CHEBI:18211
name: citrulline
def: "The parent compound of the citrulline class consisting of ornithine having a carbamoyl group at the <em>N</em><small><sup>5</small></sup>-position." []
synonym: "Citrulline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23324 ! citrullines
relationship: RO:0000087 CHEBI:59174 ! has role hapten
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018034 CHEBI:66922 ! is protonated form of citrullinate

[Term]
id: CHEBI:18220
name: isoflavone
def: "A simplest member of the class of isoflavones  that is 4<em>H</em>-chromen-4-one in which the hydrogen at position 3 is replaced by a phenyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38757 ! isoflavones
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:18222
name: xylose
def: "An aldopentose, found in the embryos of most edible plants and used in medicine to test for malabsorption by administration in water to the patient." []
synonym: "Xylose" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33916 ! aldopentose
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:18231
name: arsenic acid
def: "An arsenic oxoacid comprising one oxo group and three hydroxy groups attached to a central arsenic atom." []
is_a: CHEBI:33407 ! arsenic oxoacid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:48600 ! is protonated form of arsenate(1-)

[Term]
id: CHEBI:18237
name: glutamic acid
def: "An α-amino acid that is glutaric acid bearing a single amino substituent at position 2." []
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:50329 ! has part 2-carboxyethyl group
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:14321 ! is protonated form of glutamate(1-)

[Term]
id: CHEBI:18243
name: dopamine
def: "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group." []
synonym: "4-(2-Aminoethyl)benzene-1,2-diol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33567 ! catecholamine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:38147 ! has role cardiotonic drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:48560 ! has role dopaminergic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:59905 ! is deprotonated form of dopaminium(1+)

[Term]
id: CHEBI:18246
name: (1->4)-beta-D-glucan
def: "A β-<small>D</small>-glucan in which the glucose units are connected by (1→4) linkages." []
is_a: CHEBI:28793 ! beta-D-glucan

[Term]
id: CHEBI:18248
name: iron atom
def: "An iron group element atom that has atomic number 26." []
synonym: "Iron" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33356 ! iron group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:18252
name: zymosterol
synonym: "5alpha-Cholesta-8,24-dien-3beta-ol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35348 ! 3beta-sterol
is_a: CHEBI:50401 ! cholestanoid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018040 CHEBI:35515 ! has parent hydride 5alpha-cholestane

[Term]
id: CHEBI:18254
name: ribonucleoside
def: "Any nucleoside where the sugar component is <small>D</small>-ribose." []
is_a: CHEBI:33838 ! nucleoside
is_a: CHEBI:47019 ! dihydroxytetrahydrofuran

[Term]
id: CHEBI:18257
name: ornithine
def: "An α-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5." []
synonym: "2,5-Diaminopentanoic acid" EXACT [KEGG_COMPOUND]
synonym: "Ornithine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:46912 ! is deprotonated form of ornithinium(1+)
relationship: RO:0018034 CHEBI:32964 ! is protonated form of ornithinate

[Term]
id: CHEBI:18262
name: dodecanoate
def: "A medium-chain fatty acid anion that is the conjugate base of dodecanoic acid (lauric acid); major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:194240 ! omega-methyl-medium-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:78119 ! fatty acid anion 12:0
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:30805 ! is deprotonated form of dodecanoic acid

[Term]
id: CHEBI:18269
name: (1->6)-alpha-D-glucan
def: "An α-<small>D</small>-glucan in which the glucose units are connected by (1→6) linkages." []
is_a: CHEBI:22385 ! alpha-D-glucan

[Term]
id: CHEBI:18274
name: 2'-deoxyribonucleoside
is_a: CHEBI:23636 ! deoxyribonucleoside
is_a: CHEBI:47018 ! monohydroxytetrahydrofuran

[Term]
id: CHEBI:18276
name: dihydrogen
def: "An elemental molecule consisting of two hydrogens joined by a single bond." []
synonym: "dihydrogen" EXACT [ChEBI]
synonym: "Hydrogen" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:25362 ! elemental molecule
is_a: CHEBI:33260 ! elemental hydrogen
relationship: RO:0000087 CHEBI:15022 ! has role electron donor
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:33292 ! has role fuel
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:77974 ! has role food packaging gas

[Term]
id: CHEBI:18282
name: nucleobase
def: "That part of DNA or RNA that may be involved in pairing." []
synonym: "Base" EXACT [KEGG_COMPOUND]
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:18283
name: alpha,alpha-trehalose 6-phosphate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27084 ! trehalose phosphate
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:58429 ! is protonated form of alpha,alpha-trehalose 6-phosphate(2-)
relationship: RO:0018038 CHEBI:16551 ! has functional parent alpha,alpha-trehalose

[Term]
id: CHEBI:18287
name: L-fucose
def: "Any form of fucose having <small>L</small> configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33984 ! fucose
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:18291
name: manganese atom
synonym: "Manganese" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33352 ! manganese group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:18292
name: jasmonic acid
is_a: CHEBI:35871 ! oxo monocarboxylic acid
relationship: RO:0000087 CHEBI:24937 ! has role jasmonates
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:58431 ! is protonated form of jasmonate(1-)
relationship: RO:0018039 CHEBI:139300 ! is enantiomer of (+)-jasmonic acid

[Term]
id: CHEBI:18295
name: histamine
def: "A member of the class of imidazoles that is 1<em>H</em>-imidazole substituted at position C-4 by a 2-aminoethyl group." []
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:64365 ! aralkylamino compound
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:58432 ! is deprotonated form of histaminium

[Term]
id: CHEBI:18300
name: maleic acid
def: "A butenedioic acid in which the double bond has <i>cis</i>- (<i>Z</i>)-configuration." []
is_a: CHEBI:22958 ! butenedioic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:37156 ! is protonated form of maleate(1-)

[Term]
id: CHEBI:18308
name: acrylic acid
def: "A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group." []
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018034 CHEBI:37080 ! is protonated form of acrylate

[Term]
id: CHEBI:18310
name: alkane
def: "An acyclic branched or unbranched hydrocarbon having the general formula C<small><sub><em>n</em></sub></small>H<small><sub>2<em>n</em>+2</sub></small>, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." []
synonym: "Alkane" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24632 ! hydrocarbon
is_a: CHEBI:33653 ! aliphatic compound

[Term]
id: CHEBI:183111
name: Acoziborole
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes

[Term]
id: CHEBI:18320
name: 1,4-dithiothreitol
def: "The <i>threo</i>-diastereomer of 1,4-dimercaptobutane-2,3-diol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23853 ! dithiol
is_a: CHEBI:25189 ! 1,4-dimercaptobutane-2,3-diol
relationship: RO:0000087 CHEBI:38161 ! has role chelator
relationship: RO:0000087 CHEBI:63247 ! has role reducing agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:18332
name: L-thyroxine
def: "The <small>L</small>-enantiomer of thyroxine." []
synonym: "L-Thyroxine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:30660 ! thyroxine
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
is_a: CHEBI:84144 ! L-phenylalanine derivative
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:50671 ! has role antithyroid drug
relationship: RO:0000087 CHEBI:60311 ! has role thyroid hormone
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:60302 ! is protonated form of L-thyroxine(1-)
relationship: RO:0018036 CHEBI:58448 ! is tautomer of L-thyroxine zwitterion
relationship: RO:0018039 CHEBI:30659 ! is enantiomer of D-thyroxine

[Term]
id: CHEBI:18346
name: vanillin
def: "A member of the class of benzaldehydes carrying methoxy and hydroxy substituents at positions 3 and 4 respectively." []
synonym: "4-Hydroxy-3-methoxybenzaldehyde" EXACT [KEGG_COMPOUND]
synonym: "4-hydroxy-3-methoxybenzaldehyde" EXACT [ChemIDplus]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22698 ! benzaldehydes
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:183514
name: psora 4
def: "A member of the class of psoralens that is psoralen substituted by a 4-phenylbutoxy group at position 5. It is a potent inhibitor of the voltage-gated potassium channel K<small><sub>v</sub></small>1.3 (EC<small><sub>50</sub></small> = 3 nM)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:26369 ! psoralens
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50509 ! has role potassium channel blocker

[Term]
id: CHEBI:18361
name: diphosphate(4-)
synonym: "DIPHOSPHATE" EXACT [PDBeChem]
is_a: CHEBI:35782 ! diphosphate ion
relationship: RO:0018033 CHEBI:33019 ! is deprotonated form of diphosphate(3-)

[Term]
id: CHEBI:18367
name: phosphate(3-)
def: "A phosphate ion that is the conjugate base of hydrogenphosphate." []
synonym: "Phosphate" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35780 ! phosphate ion
is_a: CHEBI:79387 ! trivalent inorganic anion
relationship: RO:0018033 CHEBI:43474 ! is deprotonated form of hydrogenphosphate

[Term]
id: CHEBI:183694
name: Zeatin-7-N-glucoside
is_a: CHEBI:21731 ! N-glycosyl compound

[Term]
id: CHEBI:18375
name: nucleoside 3',5'-cyclic phosphate
def: "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate." []
is_a: CHEBI:23447 ! cyclic nucleotide
relationship: RO:0018034 CHEBI:58464 ! is protonated form of nucleoside 3',5'-cyclic phosphate anion

[Term]
id: CHEBI:18379
name: nitrile
def: "A compound having the structure RC≡N; thus a <em>C</em>-substituted derivative of hydrocyanic acid, HC≡N. In systematic nomenclature, the suffix nitrile denotes the triply bound ≡N atom, not the carbon atom attached to it." []
is_a: CHEBI:23424 ! cyanides
relationship: BFO:0000051 CHEBI:48819 ! has part cyano group

[Term]
id: CHEBI:18385
name: thiamine(1+)
def: "A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:26948 ! vitamin B1
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:49107 ! is deprotonated form of thiamine(2+)

[Term]
id: CHEBI:18388
name: apigenin
def: "A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7.  It induces autophagy in leukaemia cells." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27116 ! trihydroxyflavone
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018034 CHEBI:58470 ! is protonated form of apigenin-7-olate

[Term]
id: CHEBI:18401
name: phenylacetate
def: "A monocarboxylic acid anion that is the conjugate base of phenylacetic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30745 ! is deprotonated form of phenylacetic acid
relationship: RO:0018038 CHEBI:30089 ! has functional parent acetate

[Term]
id: CHEBI:184062
name: L-arginine, methyl ester
is_a: CHEBI:46874 ! alpha-amino acid ester

[Term]
id: CHEBI:18407
name: hydrogen cyanide
def: "A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom" []
is_a: CHEBI:33405 ! hydracid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:64909 ! has role poison
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17514 ! is protonated form of cyanide
relationship: RO:0018036 CHEBI:36856 ! is tautomer of hydrogen isocyanide

[Term]
id: CHEBI:184113
name: Tri-2-ethylhexyl trimellitate
is_a: CHEBI:36054 ! benzoate ester

[Term]
id: CHEBI:18421
name: superoxide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33263 ! diatomic oxygen
is_a: CHEBI:36876 ! inorganic radical anion
is_a: CHEBI:61073 ! oxygen radical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:18422
name: sulfur dioxide
synonym: "SULFUR DIOXIDE" EXACT [PDBeChem]
synonym: "Sulfur dioxide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36963 ! organooxygen compound
is_a: CHEBI:48154 ! sulfur oxide
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:78003 ! has role food bleaching agent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:184376
name: streptidine(2+)
def: "A guanidinium ion obtained by protonation of both guanidino groups of streptidine; major species at pH 7.3." []
is_a: CHEBI:60251 ! guanidinium ion
relationship: RO:0018034 CHEBI:27405 ! is protonated form of streptidine

[Term]
id: CHEBI:184579
name: Magnesium perchlorate
is_a: CHEBI:36364 ! alkaline earth salt
relationship: BFO:0000051 CHEBI:49706 ! has part perchlorate

[Term]
id: CHEBI:185646
name: 1,4-Methylimidazoleacetic acid
is_a: CHEBI:38307 ! imidazolyl carboxylic acid

[Term]
id: CHEBI:18624
name: (E)-1,3-dichloropropene
def: "A 1,3-dichloropropene with a (<i>E</i>)-configuration." []
is_a: CHEBI:18918 ! 1,3-dichloropropene
relationship: RO:0000087 CHEBI:39276 ! has role fumigant
relationship: RO:0018040 CHEBI:16052 ! has parent hydride propene

[Term]
id: CHEBI:18723
name: nicotine
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-nicotine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:17688 ! has part (S)-nicotine
relationship: BFO:0000051 CHEBI:39162 ! has part (R)-nicotine
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:47958 ! has role nicotinic acetylcholine receptor agonist
relationship: RO:0000087 CHEBI:49110 ! has role peripheral nervous system drug
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:52290 ! has role mitogen
relationship: RO:0000087 CHEBI:59163 ! has role biomarker

[Term]
id: CHEBI:1879
name: 2-(4-hydroxyphenyl)ethanol
def: "A phenol substituted at position 4 by a 2-hydroxyethyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0018038 CHEBI:49000 ! has functional parent 2-phenylethanol

[Term]
id: CHEBI:18790
name: (S)-mevalonate
def: "The (<i>S</i>)-enantiomer of mevalonate." []
is_a: CHEBI:194520 ! 3,5-dihydroxy-3-methylpentanoate
relationship: RO:0018033 CHEBI:28880 ! is deprotonated form of (S)-mevalonic acid
relationship: RO:0018039 CHEBI:36464 ! is enantiomer of (R)-mevalonate

[Term]
id: CHEBI:188074
name: rosiglitazone(1-)
is_a: CHEBI:50990 ! thiazolidinediones
relationship: RO:0018033 CHEBI:50122 ! is deprotonated form of rosiglitazone

[Term]
id: CHEBI:188144
name: chlorimuron-ethyl(1-)
is_a: CHEBI:48471 ! sulfamoylbenzoate
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0018033 CHEBI:47319 ! is deprotonated form of chlorimuron-ethyl

[Term]
id: CHEBI:188147
name: urea herbicide
def: "Any herbicide composed of urea or substituted urea substructure." []
is_a: CHEBI:24527 ! herbicide

[Term]
id: CHEBI:188148
name: organophosphorus herbicide
def: "An herbicide which contains a chemically reactive phosphate ester side chain." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:188149
name: nitrile herbicide
def: "An herbicide which has a benzene ring that contains a cyanide grouping." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:188151
name: anticoagulant rodenticide
def: "A rodenticide which contains one or more active ingredients and when consumed by rodents results in the inability to produce essential blood-clotting factors." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:18853
name: 1,1-dimethylhydrazine
def: "A member of the class of  hydrazines that is  hydrazine substituted by two methyl groups at position 1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24631 ! hydrazines
relationship: RO:0000087 CHEBI:33292 ! has role fuel
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0018038 CHEBI:15571 ! has functional parent hydrazine

[Term]
id: CHEBI:18882
name: 1,2-dichloroethene
is_a: CHEBI:23142 ! chloroethenes

[Term]
id: CHEBI:18918
name: 1,3-dichloropropene
def: "A chloropropene with two chloro substituents at positions 1 and 3 respectively.." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23162 ! chloropropene
relationship: RO:0000087 CHEBI:25491 ! has role nematicide

[Term]
id: CHEBI:18946
name: delta-lactone
def: "A lactone having a six-membered lactone ring." []
is_a: CHEBI:25000 ! lactone

[Term]
id: CHEBI:189832
name: hydroperoxy polyunsaturated fatty acid
def: "Any polyunsaturated fatty acid carrying one or more hydroperoxy substituents." []
is_a: CHEBI:194321 ! hydroperoxy unsaturated fatty acid
is_a: CHEBI:26208 ! polyunsaturated fatty acid
relationship: RO:0018034 CHEBI:134019 ! is protonated form of hydroperoxy polyunsaturated fatty acid anion

[Term]
id: CHEBI:189840
name: dicarboxylic fatty acid
def: "Any fatty acid containing two carboxy groups." []
is_a: CHEBI:35692 ! dicarboxylic acid
is_a: CHEBI:61697 ! fatty acid derivative
relationship: RO:0018034 CHEBI:189846 ! is protonated form of dicarboxylic fatty acid dianion

[Term]
id: CHEBI:189846
name: dicarboxylic fatty acid dianion
def: "Any fatty acid that contains 2 carboxylic groups. Major microspecies at pH 7.3" []
is_a: CHEBI:28965 ! dicarboxylic acid dianion
is_a: CHEBI:61697 ! fatty acid derivative
relationship: RO:0018033 CHEBI:189840 ! is deprotonated form of dicarboxylic fatty acid

[Term]
id: CHEBI:190295
name: inorganic calcium salt
def: "A calcium salt that lacks C-H bonds" []
is_a: CHEBI:167164 ! mineral nutrient
is_a: CHEBI:24839 ! inorganic salt

[Term]
id: CHEBI:190300
name: inorganic phosphate salt
def: "A phosphate salt that lacks C-H bonds" []
is_a: CHEBI:167164 ! mineral nutrient
is_a: CHEBI:24839 ! inorganic salt
is_a: CHEBI:37853 ! phosphate salt

[Term]
id: CHEBI:190303
name: inorganic potassium salt
def: "A potassium salt that lacks C-H bonds" []
is_a: CHEBI:167164 ! mineral nutrient
is_a: CHEBI:24839 ! inorganic salt
is_a: CHEBI:26218 ! potassium salt

[Term]
id: CHEBI:190358
name: azobenzene
def: "A molecule whose structure comprises two phenyl rings linked by a N=N double bond; the parent compound of the azobenzene class of compounds." []
is_a: CHEBI:22682 ! azobenzenes

[Term]
id: CHEBI:190514
name: dasatinib(1+)
def: "A tertiary ammonium ion that is the conjugate acid of dasatinib, resulting from the protonation of the piperazine tertiary amino group. Major microspecies at pH 7.3." []
is_a: CHEBI:137982 ! tertiary ammonium ion
relationship: RO:0018034 CHEBI:49375 ! is protonated form of dasatinib (anhydrous)

[Term]
id: CHEBI:190522
name: gliadin
def: "A prolamin present in wheat and several other cereals within the grass genus <em>Triticum</em>. It is made up of single-chain polypeptides with an average molecular weight of 25-100 kDa linked by intramolecular disulfide bonds and classified based on its primary amino acid sequence into the α/β-, γ- and ω-type." []
is_a: CHEBI:166885 ! prolamin

[Term]
id: CHEBI:190523
name: fructooligosaccharide
def: "carbohydrate-based polymers derived from natural sources that can be utilized by certain gastrointestinal tract bacteria but not by the host animal" []
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:190692
name: substance P(3+)
def: "A peptide cation obtained from the protonation of the amino and guanidino groups of substance P; major species at pH 7.3." []
is_a: CHEBI:60194 ! peptide cation
relationship: RO:0018034 CHEBI:80308 ! is protonated form of substance P

[Term]
id: CHEBI:191197
name: branched-chain keto acid
def: "An oxo carboxylic acid in which the parent hydrocarbon chain has one or more alkyl substituents. Derivatives formed from the first step in the metabolism of branched-chain amino acids and can provide important information on animal health and disease." []
is_a: CHEBI:25754 ! oxo carboxylic acid
relationship: RO:0018034 CHEBI:191201 ! is protonated form of branched-chain keto acid anion

[Term]
id: CHEBI:191201
name: branched-chain keto acid anion
def: "An oxo carboxylic acid anion that is the conjugate base of branched-chain keto acid resulting from the deprotonation of the carboxy group." []
is_a: CHEBI:35903 ! oxo carboxylic acid anion
relationship: RO:0018033 CHEBI:191197 ! is deprotonated form of branched-chain keto acid

[Term]
id: CHEBI:191214
name: dilevalol(1+)
def: "A secondary ammonium ion that is the conjugate acid of (<i>R</i>,<i>R</i>)-labetalol resulting from the protonation of the secondary amino group; major species at pH 7.3." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:94471 ! is protonated form of (R,R)-labetalol

[Term]
id: CHEBI:19168
name: 17-oxo steroid
def: "Any  oxo steroid carrying the oxo group at position 17." []
is_a: CHEBI:35789 ! oxo steroid
is_a: CHEBI:3992 ! cyclic ketone

[Term]
id: CHEBI:191875
name: dextran sulfate sodium
def: "An organic sodium salt of dextran sulfate. It induces colitis in mice." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: BFO:0000051 CHEBI:191931 ! has part dextran sulfate anion
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant

[Term]
id: CHEBI:191931
name: dextran sulfate anion
def: "An organosulfate oxoanion resulting from the deprotonation of the sulfo groups of dextran sulfate; major species at pH 7.3." []
is_a: CHEBI:58958 ! organosulfate oxoanion
relationship: RO:0018033 CHEBI:34674 ! is deprotonated form of dextran sulfate

[Term]
id: CHEBI:19203
name: 1H-pyrrole
def: "A tautomer of pyrrole that has the double bonds at positions 2 and 4." []
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:35556 ! pyrrole
relationship: RO:0018036 CHEBI:35557 ! is tautomer of 3H-pyrrole
relationship: RO:0018036 CHEBI:35558 ! is tautomer of 2H-pyrrole

[Term]
id: CHEBI:192484
name: ciprofloxacin zwitterion
def: "A zwitterion formed from ciprofloxacin by transfer of a proton from the carboxy to the amino group; major species at pH 7.3." []
is_a: CHEBI:27369 ! zwitterion
relationship: RO:0018036 CHEBI:100241 ! is tautomer of ciprofloxacin

[Term]
id: CHEBI:192486
name: ciprofloxacin(1+)
def: "A secondary ammonium ion that is the conjugate acid of ciprofloxacin resulting from the protonation of the NH group; major species at acidic pH." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:100241 ! is protonated form of ciprofloxacin

[Term]
id: CHEBI:192499
name: anthoxanthin
def: "are a type of flavonoid pigments in plants. Anthoxanthins are water-soluble pigments which range in color from white or colorless to a creamy to yellow, often on petals of flowers." []
is_a: CHEBI:47916 ! flavonoid

[Term]
id: CHEBI:192504
name: elicitor
def: "A chemical or biochemical compound that is introduced in small concentrations to a living system to promote the biosynthesis of the target bioactive compound." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:192527
name: ochratoxin alpha(1-)
def: "Conjugate base of ochratoxin α; major species at pH 7.3." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38758 ! isocoumarins
is_a: CHEBI:38762 ! isochromanes
relationship: RO:0018033 CHEBI:133917 ! is deprotonated form of ochratoxin alpha

[Term]
id: CHEBI:19254
name: purine 2'-deoxyribonucleoside
def: "A 2'-deoxyribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration)." []
is_a: CHEBI:18274 ! 2'-deoxyribonucleoside
is_a: CHEBI:60173 ! purine deoxyribonucleoside

[Term]
id: CHEBI:19255
name: pyrimidine 2'-deoxyribonucleoside
is_a: CHEBI:18274 ! 2'-deoxyribonucleoside
is_a: CHEBI:68472 ! pyrimidine deoxyribonucleoside

[Term]
id: CHEBI:192558
name: harmol
def: "A 9<em>H</em>-β-carboline carrying a methyl substituent at C-1 and a hydroxy group at C-7; major microspecies at pH 7.3." []
is_a: CHEBI:38958 ! indole alkaloid
is_a: CHEBI:61379 ! harmala alkaloid
relationship: RO:0000087 CHEBI:138880 ! has role autophagy inducer
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0018038 CHEBI:109895 ! has functional parent beta-carboline

[Term]
id: CHEBI:192671
name: Trenbolone acetate
is_a: CHEBI:47880 ! steroid ester

[Term]
id: CHEBI:192979
name: nystatin A2
is_a: CHEBI:59676 ! nystatins

[Term]
id: CHEBI:193111
name: methylcarbamate
def: "The conjugate base of methylcarbamic acid; major microspecies at pH 7.3." []
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:45379 ! is deprotonated form of methylcarbamic acid
relationship: RO:0018038 CHEBI:13941 ! has functional parent carbamate

[Term]
id: CHEBI:19331
name: (2,4,5-trichlorophenoxy)acetate
def: "A chlorophenoxyacetate anion obtained by deprotonation of the carboxy group of (2,4,5-trichlorophenoxy)acetic acid." []
is_a: CHEBI:23151 ! chlorophenoxyacetate anion
relationship: RO:0018033 CHEBI:27903 ! is deprotonated form of (2,4,5-trichlorophenoxy)acetic acid

[Term]
id: CHEBI:193350
name: ferulic acid
def: "A member of the class of ferulic acids that is cinnamic acid substituted by a methoxy and a hydroxy group at positions 3 and 4 of the phenyl ring." []
is_a: CHEBI:24031 ! ferulic acids
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:19351
name: (2,4-dichlorophenoxy)acetate
def: "A chlorophenoxyacetate anion that is the conjugate base of  (2,4-dichlorophenoxy)acetic acid, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:23151 ! chlorophenoxyacetate anion
relationship: RO:0018033 CHEBI:28854 ! is deprotonated form of 2,4-D

[Term]
id: CHEBI:193572
name: protectin
def: "Docosanoids characterized by the presence of a conjugated system of double bonds." []
is_a: CHEBI:131863 ! docosanoid

[Term]
id: CHEBI:19391
name: 2,6-dibromophenol
def: "A dibromophenol that is phenol in which both of the hydrogens that are <em>ortho</em> to the phenolic hydroxy group have been replaced by bromines." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:33625 ! dibromophenol
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0018038 CHEBI:37151 ! has functional parent 1,3-dibromobenzene

[Term]
id: CHEBI:194095
name: mitomycin C(1-)
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0018033 CHEBI:27504 ! is deprotonated form of mitomycin C

[Term]
id: CHEBI:194135
name: 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
def: "An oxazinoquinoline that is 2,3-dihydro-7<em>H</em>-[1,4]oxazino[2,3,4-<em>ij</em>]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively." []
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:46920 ! N-methylpiperazine
is_a: CHEBI:47881 ! 3-oxo monocarboxylic acid
is_a: CHEBI:53665 ! oxazinoquinoline

[Term]
id: CHEBI:194137
name: neurokinin-1 receptor agonist
def: "An agonist at the neurokinin-1 receptor." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:194147
name: aristolochic acids
def: "Organic heterotetracyclic compounds which are a group of nitro phenanthrene organic acids, naturally found in many kinds of plants, such as <em>Aristolochia</em> and <em>Asarum</em>, and widely cultivated in Asia.They are identified as a class 1 human carcinogen by the International Agency for Research on Cancer owing to their carcinogenicity and nephrotoxicity and can pose a significant hazard to food safety and human health." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:38163 ! organic heterotetracyclic compound
is_a: CHEBI:59770 ! cyclic acetal
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:61015 ! has role nephrotoxin

[Term]
id: CHEBI:194148
name: polybutylene adipate terephthalate
def: "A random copolymer of adipic acid, 1,4-butanediol and terephthalic acid." []
is_a: CHEBI:53521 ! random copolymer

[Term]
id: CHEBI:194240
name: omega-methyl-medium-chain fatty acid anion
def: "A medium-chain fatty acid anion obtained by deprotonation of the carboxy group of any ω-methyl fatty acid; major species at pH 7.3." []
is_a: CHEBI:59558 ! medium-chain fatty acid anion
is_a: CHEBI:76619 ! omega-methyl fatty acid anion

[Term]
id: CHEBI:194306
name: omega-hydroxy-short-chain fatty acid
def: "A ω-hydroxy-fatty acid with a chain length of less than C<small><sub>6</sub></small>." []
is_a: CHEBI:10615 ! omega-hydroxy fatty acid
is_a: CHEBI:26666 ! short-chain fatty acid

[Term]
id: CHEBI:19432
name: 2-acetamidofluorenes
def: "An <em>ortho</em>-fused polycyclic arene, or derivative thereof, that consists of 9<em>H</em>-fluorene bearing an acetamido substituent at position 2." []
is_a: CHEBI:24059 ! fluorenes

[Term]
id: CHEBI:194321
name: hydroperoxy unsaturated fatty acid
def: "Any unsaturated fatty acid carrying one or more hydroperoxy substituents." []
is_a: CHEBI:27208 ! unsaturated fatty acid
is_a: CHEBI:64009 ! hydroperoxy fatty acid

[Term]
id: CHEBI:194338
name: T-type calcium channel blocker
def: "Any agent that interferes with the activity of T-type calcium channels." []
is_a: CHEBI:38215 ! calcium channel blocker

[Term]
id: CHEBI:194423
name: aquaretic
def: "A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss)." []
is_a: CHEBI:35498 ! diuretic

[Term]
id: CHEBI:194491
name: N-acetyl-beta-D-muramoyl-L-alanyl-D-isoglutamine(1-)
def: "Conjugate base of muramyl dipeptide. Major species at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:59414 ! is deprotonated form of muramyl dipeptide

[Term]
id: CHEBI:194519
name: 3,5-dihydroxy-3-methylpentanoic acid
def: "A dihydroxy monocarboxylic acid comprising valeric acid having two hydroxy groups at the 3- and 5-positions together with a methyl group at the 3-position." []
is_a: CHEBI:35972 ! dihydroxy monocarboxylic acid
relationship: RO:0018034 CHEBI:194520 ! is protonated form of 3,5-dihydroxy-3-methylpentanoate
relationship: RO:0018038 CHEBI:17418 ! has functional parent valeric acid

[Term]
id: CHEBI:19452
name: 2-amino-4,6-dinitrotoluene
def: "An amino-nitrotoluene that is 4,6-dinitrotoluene substituted at position 2 by an amino group." []
is_a: CHEBI:22482 ! amino-nitrotoluene
relationship: RO:0000087 CHEBI:63490 ! has role explosive
relationship: RO:0000087 CHEBI:76968 ! has role fungal xenobiotic metabolite

[Term]
id: CHEBI:194520
name: 3,5-dihydroxy-3-methylpentanoate
def: "A hydroxy monocarboxylic acid anion that is the conjugate base of 3,5-dihydroxy-3-methylpentanoic acid resulting from the deprotonation of the carboxy group; Major species at pH 7.3." []
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0018033 CHEBI:194519 ! is deprotonated form of 3,5-dihydroxy-3-methylpentanoic acid
relationship: RO:0018038 CHEBI:31011 ! has functional parent valerate

[Term]
id: CHEBI:194548
name: 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
def: "A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen." []
is_a: CHEBI:33567 ! catecholamine

[Term]
id: CHEBI:19503
name: propachlor
def: "An anilide that consists of 2-chloroacetanilide bearing an <em>N</em>-isopropyl substituent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13248 ! anilide
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:195233
name: diethyl 2-sulfanylbutanedioate
def: "A diester resulting from the formal condensation of the carboxy groups of thiomalic acid with ethanol. It is a metabolite of the insecticide malathion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:51307 ! diester
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0018038 CHEBI:38705 ! has functional parent thiomalic acid

[Term]
id: CHEBI:195237
name: alkenylbenzene
def: "A member of the class of benzenes that is benzene substituted with one or more alkenyl groups. It is a group of naturally occurring compounds that are synthesized as secondary metabolites in various plants, including nutmeg and basil." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:195280
name: artemether
def: "An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of <em>falciparum</em> malaria." []
is_a: CHEBI:26658 ! sesquiterpenoid
is_a: CHEBI:59770 ! cyclic acetal
is_a: CHEBI:63920 ! artemisinin derivative
is_a: CHEBI:72588 ! semisynthetic derivative
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:195348
name: protectin D1(1-)
def: "A dihydroxydocosahexaenoate that is the conjugate base of protectin D1, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:136528 ! dihydroxydocosahexaenoate
relationship: RO:0018033 CHEBI:138655 ! is deprotonated form of protectin D1

[Term]
id: CHEBI:195541
name: JTE-013
def: "A semicarbazide derivative that is semicarbazide in which the amino group at position 2 is replaced by a [1,3-dimethyl-4-(propan-2-yl)-1<em>H</em>-pyrazolo[3,4-<em>b</em>]pyridin-6-yl]amino group and the amino group adjacent to the carbonyl is replaced by a (2,6-dichloropyridin-4-yl)amino group. It is a potent S1P2 antagonist (IC<small><sub>50</sub></small> = 17.6 nM)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39173 ! chloropyridine
is_a: CHEBI:46699 ! pyrazolopyridine
relationship: RO:0000087 CHEBI:195542 ! has role sphingosine-1-phosphate receptor 2 antagonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:63054 ! has role osteogenesis regulator
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:72571 ! has role pro-angiogenic agent
relationship: RO:0018038 CHEBI:28306 ! has functional parent semicarbazide

[Term]
id: CHEBI:195542
name: sphingosine-1-phosphate receptor 2 antagonist
def: "Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist for the subtype 2 receptors (S1PR2)." []
is_a: CHEBI:144987 ! sphingosine-1-phosphate receptor antagonist

[Term]
id: CHEBI:195544
name: aspartame zwitterion
def: "A dipeptide zwitterion resulting from transfer of a proton from the carboxy to the amino group of aspartame; major species at pH 7.3." []
is_a: CHEBI:90799 ! dipeptide zwitterion
relationship: RO:0018036 CHEBI:2877 ! is tautomer of aspartame

[Term]
id: CHEBI:197435
name: alpha-pyrrolidinobutiophenone
is_a: CHEBI:46775 ! N-alkylpyrrolidine
is_a: CHEBI:76224 ! aromatic ketone

[Term]
id: CHEBI:197449
name: NMR solvent
def: "A solvent used in nuclear magnetic resonance (NMR) spectroscopy." []
is_a: CHEBI:46787 ! solvent

[Term]
id: CHEBI:197507
name: short-chain fatty alcohol
def: "A fatty alcohol with a chain length of less than C<small><sub>6</sub></small>." []
is_a: CHEBI:24026 ! fatty alcohol

[Term]
id: CHEBI:19834
name: 3',5'-cyclic purine nucleotide
is_a: CHEBI:18375 ! nucleoside 3',5'-cyclic phosphate
is_a: CHEBI:36982 ! cyclic purine nucleotide

[Term]
id: CHEBI:201492
name: Proteinase K
is_a: CHEBI:46633 ! carbapenems

[Term]
id: CHEBI:20156
name: 3-oxo-Delta(1) steroid
def: "Any 3-oxo steroid that contains a double bond between positions 1 and 2." []
is_a: CHEBI:47788 ! 3-oxo steroid
is_a: CHEBI:51689 ! enone

[Term]
id: CHEBI:201815
name: Monensin sodium salt
is_a: CHEBI:59777 ! ketal

[Term]
id: CHEBI:20313
name: 4-aminobenzenesulfonate
def: "An aminobenzenesulfonate that is the conjugate base of 4-aminobenzenesulfonic acid." []
is_a: CHEBI:22493 ! aminobenzenesulfonate
relationship: RO:0000087 CHEBI:76206 ! has role xenobiotic metabolite
relationship: RO:0018033 CHEBI:27500 ! is deprotonated form of 4-aminobenzenesulfonic acid

[Term]
id: CHEBI:20331
name: 4-chloroaniline
def: "A chloroaniline in which the chloro atom is <em>para</em> to the aniline amino group." []
synonym: "4-Chloroaniline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23130 ! chloroaniline
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:203402
name: 4-Bromo-9-(iodomethyl)-1,5,12-trimethyl-8-oxatricyclo dodeca-2,4,6-triene
is_a: CHEBI:38443 ! 1-benzopyran

[Term]
id: CHEBI:2038
name: 5-azacytidine
def: "An <em>N</em>-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1<em>H</em>)-one substituted by a β-<small>D</small>-ribofuranosyl residue via an <em>N</em>-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48009 ! N-glycosyl-1,3,5-triazine
is_a: CHEBI:60783 ! nucleoside analogue
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:47002 ! has functional parent beta-D-ribose

[Term]
id: CHEBI:20432
name: imidazolone
is_a: CHEBI:24780 ! imidazoles

[Term]
id: CHEBI:204928
name: cefotaxime
def: "A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups." []
is_a: CHEBI:23066 ! cephalosporin
is_a: CHEBI:36816 ! oxime O-ether
is_a: CHEBI:38418 ! 1,3-thiazoles
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0018034 CHEBI:53670 ! is protonated form of cefotaxime(1-)

[Term]
id: CHEBI:20551
name: mesalaminate(1-)
def: "A hydroxybenzoate that is the conjugate base of mesalamine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:22494 ! aminobenzoate
is_a: CHEBI:24675 ! hydroxybenzoate
relationship: RO:0018033 CHEBI:6775 ! is deprotonated form of mesalamine
relationship: RO:0018038 CHEBI:30762 ! has functional parent salicylate

[Term]
id: CHEBI:20569
name: EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor
def: "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19)." []
is_a: CHEBI:76663 ! EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor

[Term]
id: CHEBI:20612
name: 5-methyltetrahydrofolate
def: "A group of heterocyclic compounds based on the 5-methyl-5,6,7,8-tetrahydropteroic acid skeleton conjugated with one or more <small>L</small>-glutamic acid or <small>L</small>-glutamate units." []
is_a: CHEBI:25345 ! methyltetrahydrofolate

[Term]
id: CHEBI:20664
name: 5beta-cholane
is_a: CHEBI:35519 ! cholane

[Term]
id: CHEBI:20702
name: 2-aminopurines
def: "Any aminopurine having the amino substituent at the 2-position." []
is_a: CHEBI:22527 ! aminopurine

[Term]
id: CHEBI:20706
name: 6-aminopurines
def: "Any compound having 6-aminopurine (adenine) as part of its structure." []
is_a: CHEBI:22527 ! aminopurine

[Term]
id: CHEBI:207229
name: dihydroartemisinin
def: "A sesquiterpenoid compound which is used as a drug for treatment of malaria." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26658 ! sesquiterpenoid
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial

[Term]
id: CHEBI:207496
name: furfuryl alcohol
def: "A furan bearing a hydroxymethyl substituent at the 2-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:24129 ! furans
relationship: RO:0000087 CHEBI:77523 ! has role Maillard reaction product

[Term]
id: CHEBI:20854
name: ATP synthase inhibitor
def: "A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase." []
is_a: CHEBI:25355 ! mitochondrial respiratory-chain inhibitor
is_a: CHEBI:73216 ! EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor

[Term]
id: CHEBI:20857
name: C-glycosyl compound
def: "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a carbon atom, thus creating a C-C bond." []
is_a: CHEBI:63161 ! glycosyl compound

[Term]
id: CHEBI:20858
name: C19-gibberellin
is_a: CHEBI:24250 ! gibberellin

[Term]
id: CHEBI:214314
name: Heptelidic acid
is_a: CHEBI:37668 ! terpene lactone

[Term]
id: CHEBI:21501
name: N-acetyl-D-amino acid
def: "An <em>N</em>-acetyl-amino acid having <small>D</small>-configuration." []
is_a: CHEBI:15778 ! N-acyl-D-amino acid
is_a: CHEBI:21575 ! N-acetyl-amino acid
relationship: RO:0018034 CHEBI:58496 ! is protonated form of N-acetyl-D-amino acid anion
relationship: RO:0018039 CHEBI:21545 ! is enantiomer of N-acetyl-L-amino acid

[Term]
id: CHEBI:21545
name: N-acetyl-L-amino acid
def: "An <small>L</small>-amino acid having an <em>N</em>-acetyl substituent." []
is_a: CHEBI:21575 ! N-acetyl-amino acid
is_a: CHEBI:21644 ! N-acyl-L-amino acid
relationship: RO:0018039 CHEBI:21501 ! is enantiomer of N-acetyl-D-amino acid

[Term]
id: CHEBI:21575
name: N-acetyl-amino acid
def: "An <em>N</em>-acyl-amino acid that has acetyl as the acyl group." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:22195 ! acetyl-amino acid
is_a: CHEBI:51569 ! N-acyl-amino acid
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:21601
name: N-acetyl-D-hexosamine
def: "Any <em>N</em>-acetylhexosamine in which the hexosamine has <small>D</small>-configuration. The structure provided is an illustrative example of the pyranose form of an <em>N</em>-acetyl-<small>D</small>-hexosamine." []
is_a: CHEBI:7203 ! N-acetylhexosamine

[Term]
id: CHEBI:21638
name: N-acylglucosamine
is_a: CHEBI:21656 ! N-acyl-hexosamine
is_a: CHEBI:24271 ! glucosamines

[Term]
id: CHEBI:21644
name: N-acyl-L-amino acid
def: "Any <em>N</em>-acylamino acid having <small>L</small>-configuration." []
is_a: CHEBI:51569 ! N-acyl-amino acid
relationship: RO:0018039 CHEBI:15778 ! is enantiomer of N-acyl-D-amino acid

[Term]
id: CHEBI:21650
name: N-acyl-L-glutamic acid
def: "Any optically active <em>N</em>-acylglutamic acid having <small>L</small>-configuration." []
is_a: CHEBI:21658 ! N-acylglutamic acid
is_a: CHEBI:48927 ! N-acyl-L-alpha-amino acid
is_a: CHEBI:83982 ! L-glutamic acid derivative

[Term]
id: CHEBI:21656
name: N-acyl-hexosamine
is_a: CHEBI:24586 ! hexosamine

[Term]
id: CHEBI:21658
name: N-acylglutamic acid
def: "A glutamic acid derivative that is glutamic acid in which a hydrogen attached to the nitrogen has been replaced by an acyl group." []
is_a: CHEBI:24315 ! glutamic acid derivative

[Term]
id: CHEBI:21672
name: N-amidino-amino acid
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:21689
name: N-carbamoyl-amino acid
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:21731
name: N-glycosyl compound
def: "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond." []
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:63161 ! glycosyl compound

[Term]
id: CHEBI:21759
name: N-methyl-N'-nitro-N-nitrosoguanidine
def: "An <em>N</em>-nitroguanidine compound having nitroso and methyl substituents at the <em>N</em>'-position" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35800 ! nitroso compound
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0018038 CHEBI:39179 ! has functional parent nitroguanidine

[Term]
id: CHEBI:21760
name: N-methyl-amino acid
def: "An amino acid derivative in which at least one of the hydrogens of the amino group has been replaced by a methyl group." []
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:21766
name: N-methylglycines
def: "An <em>N</em>-alkylglycine that is sarcosine and derivatives of sarcosine arising by replacement of the hydrogen attached to the nitrogen by a hydrocarbyl group." []
is_a: CHEBI:66933 ! N-alkylglycine

[Term]
id: CHEBI:22063
name: sulfoxide
def: "An organosulfur compound having the structure R<small><sub>2</sub></small>S=O or R<small><sub>2</sub></small>C=S=O (R ≠ H)." []
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:2208
name: purine-6-thiol
def: "A thiol that is the tautomer of mercaptopurine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26401 ! purines
is_a: CHEBI:82711 ! aryl thiol
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018036 CHEBI:50667 ! is tautomer of mercaptopurine
relationship: RO:0018040 CHEBI:17258 ! has parent hydride 7H-purine

[Term]
id: CHEBI:22152
name: 2-cis-abscisic acid
def: "A member of the class of abscisic acids in which the double bond betweeen positions 2 and 3 has <i>cis</i>- (natural) geometry." []
is_a: CHEBI:62431 ! abscisic acids
relationship: RO:0000087 CHEBI:73191 ! has role abscisic acid receptor agonist
relationship: RO:0018034 CHEBI:62071 ! is protonated form of 2-cis-abscisate

[Term]
id: CHEBI:22153
name: acaricide
def: "A substance used to destroy pests of the subclass <em>Acari</em> (mites and ticks)." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:22160
name: acetamides
def: "Compounds with the general formula RNHC(=O)CH<small><sub>3</sub></small>." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:22177
name: acetohydroxamic acids
def: "Any hydroxamic acid in which the <em>N</em>-acyl group is specified as acetyl." []
is_a: CHEBI:24650 ! hydroxamic acid

[Term]
id: CHEBI:22180
name: EC 2.2.1.6 (acetolactate synthase) inhibitor
def: "An EC 2.2.1.* (transketolase/transaldolase) inhibitor that interferes with the action of acetolactate synthase (EC 2.2.1.6)." []
is_a: CHEBI:76876 ! EC 2.2.1.* (transketolase/transaldolase) inhibitor

[Term]
id: CHEBI:22187
name: acetophenones
def: "A class or aromatic ketone consisting of acetophenone, PhC(=O)CH<small><sub>3</sub></small>, and its substituted derivatives." []
is_a: CHEBI:51867 ! methyl ketone
is_a: CHEBI:76224 ! aromatic ketone

[Term]
id: CHEBI:22195
name: acetyl-amino acid
def: "Any amino acid derivative that is the <em>N</em>-acetyl or <em>O</em>-acetyl derivative of an amino acid." []
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:22198
name: acetylcysteine
is_a: CHEBI:22195 ! acetyl-amino acid
is_a: CHEBI:23509 ! cysteine derivative

[Term]
id: CHEBI:22204
name: acetylspermidine
is_a: CHEBI:22160 ! acetamides
relationship: RO:0018038 CHEBI:16610 ! has functional parent spermidine

[Term]
id: CHEBI:22216
name: acrylamides
def: "An enamide which is acrylamide or a derivative of acrylamide obtained by replacement of one or more of its hydrogens." []
is_a: CHEBI:51751 ! enamide

[Term]
id: CHEBI:22221
name: acyl group
def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> ≠ 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." []
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:22256
name: adenosine phosphate
is_a: CHEBI:61296 ! adenyl ribonucleotide
relationship: RO:0018038 CHEBI:16335 ! has functional parent adenosine

[Term]
id: CHEBI:22260
name: adenosines
def: "Any purine ribonucleoside that is a derivative of adenosine." []
is_a: CHEBI:26399 ! purine ribonucleoside
relationship: RO:0018038 CHEBI:16708 ! has functional parent adenine

[Term]
id: CHEBI:22271
name: aflatoxin
def: "Any of a group of related and highly toxic secondary metabolites (mycotoxins) whose main structural feature is a fused coumarin-bis(dihydrofuran) ring system and which are produced by strains of the moulds <em>Aspergillus flavus</em> or <em>A. parasiticus</em>, together with further metabolites of these mycotoxins" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48210 ! cyclopentafurofurochromene
relationship: RO:0000087 CHEBI:25442 ! has role mycotoxin

[Term]
id: CHEBI:22278
name: alanine derivative
def: "An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of alanine by a heteroatom. The definition normally excludes peptides containing alanine residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:16449 ! has functional parent alanine

[Term]
id: CHEBI:22289
name: aldaric acid anion
is_a: CHEBI:33721 ! carbohydrate acid anion
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:22290 ! is deprotonated form of aldaric acid

[Term]
id: CHEBI:22290
name: aldaric acid
def: "Dicarboxylic acids formed from aldoses by replacement of both terminal groups (CHO and CH<small><sub>2</sub></small>OH) by carboxy groups." []
is_a: CHEBI:33720 ! carbohydrate acid
is_a: CHEBI:35692 ! dicarboxylic acid
relationship: RO:0018034 CHEBI:22289 ! is protonated form of aldaric acid anion

[Term]
id: CHEBI:22297
name: alditol phosphate
is_a: CHEBI:26816 ! carbohydrate phosphate
is_a: CHEBI:63423 ! alditol derivative

[Term]
id: CHEBI:22307
name: aldoxime
def: "Oximes of aldehydes RCH=NOH." []
is_a: CHEBI:25750 ! oxime

[Term]
id: CHEBI:22313
name: alkaline earth metal atom
is_a: CHEBI:33318 ! main group element atom
is_a: CHEBI:33521 ! metal atom
is_a: CHEBI:33559 ! s-block element atom

[Term]
id: CHEBI:22314
name: alkali metal atom
is_a: CHEBI:33318 ! main group element atom
is_a: CHEBI:33521 ! metal atom
is_a: CHEBI:33559 ! s-block element atom

[Term]
id: CHEBI:22315
name: alkaloid
def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is  exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:22323
name: alkyl group
def: "A univalent group ‒C<small><sub><em>n</em></sub></small>H<small><sub>2<em>n</em>+1</sub></small> derived from an alkane by removal of a hydrogen atom from any carbon atom." []
is_a: CHEBI:33248 ! hydrocarbyl group
relationship: RO:0018037 CHEBI:18310 ! is substitutent group from alkane

[Term]
id: CHEBI:22324
name: alkyl phosphate
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:37734 ! phosphoric ester

[Term]
id: CHEBI:22327
name: aliphatic sulfide
is_a: CHEBI:16385 ! organic sulfide

[Term]
id: CHEBI:22331
name: alkylamines
def: "Any amine formally derived from ammonia by replacing one, two or three hydrogen atoms by alkyl groups." []
is_a: CHEBI:32952 ! amine

[Term]
id: CHEBI:223316
name: (+)-artemisinin
def: "A sesquiterpene lactone obtained from sweet wormwood, <em>Artemisia annua</em>, which is used as an antimalarial for the treatment of multi-drug resistant strains of <em>falciparum</em> malaria." []
is_a: CHEBI:25702 ! organic peroxide
is_a: CHEBI:37667 ! sesquiterpene lactone
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:22333
name: alkylating agent
def: "Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases." []
is_a: CHEBI:25435 ! mutagen

[Term]
id: CHEBI:22339
name: alkyne
def: "Acyclic branched or unbranched hydrocarbons having a carbon-carbon triple bond and the general formula C<small><sub><em>n</em></sub></small>H<small><sub>2<em>n</em>−2</sub></small>, RC≡CR." []
is_a: CHEBI:33650 ! acyclic acetylene

[Term]
id: CHEBI:22385
name: alpha-D-glucan
is_a: CHEBI:37163 ! glucan

[Term]
id: CHEBI:22455
name: alpha-hydroxynitrile
def: "A hydroxynitrile in which the hydroxy group is located on the carbon α to the carbonitrile group." []
is_a: CHEBI:24730 ! hydroxynitrile

[Term]
id: CHEBI:22470
name: alpha-tocopherol
def: "A tocopherol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a 4,8,12-trimethyltridecyl group at position 2." []
is_a: CHEBI:27013 ! tocopherol
is_a: CHEBI:33234 ! vitamin E
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77962 ! has role food antioxidant

[Term]
id: CHEBI:22472
name: ametryn
def: "A methylthio-1,3,5-triazine that is 2-(methylsulfanyl)-1,3,5-triazine substituted by an ethylamino and an isopropylamino group at positions 4 and 6 respectively." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38174 ! methylthio-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:22475
name: amino acid amide
def: "An amide of an amino acid formed formally by conversion of the carboxy group to a carboxamido group." []
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:22478
name: amino alcohol
def: "An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group." []
is_a: CHEBI:30879 ! alcohol
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:22479
name: amino cyclitol glycoside
is_a: CHEBI:23451 ! cyclitol
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:22482
name: amino-nitrotoluene
def: "A nitrotoluene carrying at least one amino group." []
is_a: CHEBI:25566 ! nitrotoluene
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:22492
name: amino aldehyde
def: "Any aldehyde which contains an amino group." []
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:22493
name: aminobenzenesulfonate
is_a: CHEBI:22713 ! arenesulfonate oxoanion
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:22494
name: aminobenzoate
is_a: CHEBI:22718 ! benzoates
relationship: RO:0018033 CHEBI:22495 ! is deprotonated form of aminobenzoic acid

[Term]
id: CHEBI:22495
name: aminobenzoic acid
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:33856 ! aromatic amino acid
relationship: RO:0018034 CHEBI:22494 ! is protonated form of aminobenzoate

[Term]
id: CHEBI:22496
name: aminobiphenyl
def: "Any member of the class of biphenyls in which the biphenyl skeleton is substituted by at least one amino group." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:50471 ! primary arylamine

[Term]
id: CHEBI:22501
name: aminodiol
def: "An amino alcohol having two hydroxy functional groups." []
is_a: CHEBI:22478 ! amino alcohol
is_a: CHEBI:23824 ! diol

[Term]
id: CHEBI:22506
name: aminoglycan
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:65212 ! polysaccharide derivative

[Term]
id: CHEBI:22507
name: aminoglycoside antibiotic
is_a: CHEBI:23007 ! carbohydrate-containing antibiotic
is_a: CHEBI:47779 ! aminoglycoside

[Term]
id: CHEBI:22512
name: aminoimidazole
def: "Any member of the class of  imidazoles carrying at least one amino substituent." []
is_a: CHEBI:24780 ! imidazoles

[Term]
id: CHEBI:22527
name: aminopurine
def: "Any purine having at least one amino substituent." []
is_a: CHEBI:26401 ! purines

[Term]
id: CHEBI:22531
name: aminotoluene
def: "Any member of the class of  toluenes carrying one or more amino groups." []
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:225519
name: 1-ethyl-beta-carboline-3-carboxylic acid
is_a: CHEBI:61379 ! harmala alkaloid

[Term]
id: CHEBI:22562
name: anilines
def: "Any  aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:33860 ! aromatic amine

[Term]
id: CHEBI:22563
name: anion
def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." []
is_a: CHEBI:24870 ! ion

[Term]
id: CHEBI:22565
name: ansamycin
def: "A class of macrocyclic lactams that consist of an aromatic (phenyl or naphthyl) or quinonoid (benzoquinone or naphthoquinone) moiety that is bridged by an aliphatic chain." []
is_a: CHEBI:24995 ! lactam
is_a: CHEBI:26188 ! polyketide
is_a: CHEBI:51026 ! macrocycle

[Term]
id: CHEBI:22580
name: anthraquinone
is_a: CHEBI:46955 ! anthracenes
is_a: CHEBI:51285 ! acenoquinone

[Term]
id: CHEBI:22583
name: antifeedant
def: "A substance that prevents pests from feeding." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:22586
name: antioxidant
def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:22587
name: antiviral agent
def: "A substance that destroys or inhibits replication of viruses." []
is_a: CHEBI:33281 ! antimicrobial agent

[Term]
id: CHEBI:22599
name: arabinose
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33916 ! aldopentose
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:22601
name: arabinoside
is_a: CHEBI:35312 ! pentoside

[Term]
id: CHEBI:22629
name: arsenate ion
is_a: CHEBI:35776 ! arsenic oxoanion
relationship: RO:0018033 CHEBI:18231 ! is deprotonated form of arsenic acid

[Term]
id: CHEBI:22632
name: arsenic molecular entity
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: BFO:0000051 CHEBI:27563 ! has part arsenic atom

[Term]
id: CHEBI:22633
name: arsenite ion
def: "An arsenic oxoanion resulting from the removal of one or more protons from arsenous acid." []
is_a: CHEBI:24834 ! inorganic anion
is_a: CHEBI:35776 ! arsenic oxoanion

[Term]
id: CHEBI:22637
name: arsine
def: "Arsane (AsH<small><sub>3</sub></small>) and compounds derived from it by substituting one, two or three hydrogen atoms by hydrocarbyl groups: RAsH<small><sub>2</sub></small>, R<small><sub>2</sub></small>AsH, R<small><sub>3</sub></small>As (R ≠ H) are called primary, secondary and tertiary arsines, respectively. A specific arsine is preferably named as a substituted arsane." []
is_a: CHEBI:22632 ! arsenic molecular entity

[Term]
id: CHEBI:22638
name: organoarsonic acid
def: "Any organoarsenic compound that is the As-organyl derivative of arsonic acid." []
is_a: CHEBI:33406 ! organoarsenic compound
relationship: RO:0018038 CHEBI:29850 ! has functional parent arsonic acid

[Term]
id: CHEBI:22644
name: arylalkylamine
is_a: CHEBI:22331 ! alkylamines

[Term]
id: CHEBI:22645
name: arenecarboxamide
def: "A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system." []
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:62733 ! aromatic amide

[Term]
id: CHEBI:22651
name: ascorbate
def: "A ketoaldonate that is the conjugate base of ascorbic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24961 ! ketoaldonate
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0018033 CHEBI:22652 ! is deprotonated form of ascorbic acid

[Term]
id: CHEBI:22652
name: ascorbic acid
is_a: CHEBI:24963 ! ketoaldonic acid
relationship: RO:0018034 CHEBI:22651 ! is protonated form of ascorbate

[Term]
id: CHEBI:22653
name: asparagine
def: "An α-amino acid in which one of the hydrogens attached to the α-carbon of glycine is substituted by a 2-amino-2-oxoethyl group." []
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:35735 ! dicarboxylic acid monoamide
relationship: BFO:0000051 CHEBI:50330 ! has part 2-amino-2-oxoethyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:32661 ! is deprotonated form of asparaginium
relationship: RO:0018034 CHEBI:32660 ! is protonated form of asparaginate

[Term]
id: CHEBI:22658
name: aspartate family amino acid
def: "An <small>L</small>-α-amino acid which is <small>L</small>-aspartic acid or any of the essential amino acids biosynthesised from it (asparagine, lysine, methionine, threonine and isoleucine). A closed class." []
is_a: CHEBI:15705 ! L-alpha-amino acid
is_a: CHEBI:83813 ! proteinogenic amino acid

[Term]
id: CHEBI:22660
name: aspartic acid
def: "An α-amino acid that consists of succinic acid bearing a single α-amino substituent" []
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:66873 ! C4-dicarboxylic acid
relationship: BFO:0000051 CHEBI:41402 ! has part carboxymethyl group
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:35391 ! is protonated form of aspartate(1-)

[Term]
id: CHEBI:22661
name: aspartic acid derivative
def: "An amino acid derivative resulting from reaction of aspartic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen of aspartic acid by a heteroatom. The definition normally excludes peptides containing aspartic acid residues." []
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:22676
name: auxin
def: "Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek αυξανω, \"to grow\")." []
is_a: CHEBI:37848 ! plant hormone

[Term]
id: CHEBI:22681
name: aziridines
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:22682
name: azobenzenes
def: "Any member of the wide class of molecules that share the core azobenzene structure, comprising two phenyl rings linked by a N=N double bond, which may have different functional groups extending from the rings." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:37533 ! azo compound

[Term]
id: CHEBI:22689
name: bafilomycin A1
def: "The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from <em>Streptomyces griseus</em>." []
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:46942 ! oxanes
is_a: CHEBI:59780 ! cyclic hemiketal
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:49200 ! has role EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:73214 ! has role EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:88227 ! has role potassium ionophore
relationship: RO:0000087 CHEBI:88230 ! has role autophagy inhibitor

[Term]
id: CHEBI:22693
name: barbiturates
def: "Members of the class of pyrimidones consisting of pyrimidine-2,4,6(1<em>H</em>,3<em>H</em>,5<em>H</em>)-trione (barbituric acid) and its derivatives. Largest group of the synthetic sedative/hypnotics, sharing a characteristic six-membered ring structure." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38337 ! pyrimidone
relationship: RO:0000087 CHEBI:50268 ! has role GABA modulator

[Term]
id: CHEBI:22695
name: base
def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Brønsted base) or with the vacant orbital of some other molecular entity (Lewis base)." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:22698
name: benzaldehydes
def: "Any arenecarbaldehyde that consists of a formyl substituted benzene ring and its substituted derivatives thereof." []
is_a: CHEBI:33855 ! arenecarbaldehyde

[Term]
id: CHEBI:22702
name: benzamides
is_a: CHEBI:22645 ! arenecarboxamide

[Term]
id: CHEBI:22707
name: benzenetriol
def: "A triol in which three hydroxy groups are substituted onto a benzene ring." []
is_a: CHEBI:27136 ! triol
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:22712
name: benzenes
def: "Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives." []
is_a: CHEBI:33836 ! benzenoid aromatic compound

[Term]
id: CHEBI:22713
name: arenesulfonate oxoanion
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:33555 ! is deprotonated form of arenesulfonic acid

[Term]
id: CHEBI:22715
name: benzimidazoles
def: "An organic heterocyclic compound containing a benzene ring fused to an imidazole ring." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:22718
name: benzoates
def: "A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
is_a: CHEBI:91007 ! aromatic carboxylate

[Term]
id: CHEBI:22720
name: benzodiazepine
def: "A group of heterocyclic compounds with a core structure containing a benzene ring fused to a diazepine ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound
relationship: RO:0000087 CHEBI:50268 ! has role GABA modulator

[Term]
id: CHEBI:22723
name: benzoic acids
def: "Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:33859 ! aromatic carboxylic acid

[Term]
id: CHEBI:22726
name: benzophenones
def: "Any aromatic ketone in which the carbonyl group is bonded to 2 phenyl groups." []
is_a: CHEBI:76224 ! aromatic ketone

[Term]
id: CHEBI:22727
name: benzopyran
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:22728
name: benzopyrrole
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38180 ! polycyclic heteroarene

[Term]
id: CHEBI:22729
name: benzoquinones
def: "Any quinone resulting from the formal oxidation of catechol, hydroquinone, or their <em>C</em>-substituted derivatives." []
is_a: CHEBI:36141 ! quinone

[Term]
id: CHEBI:22743
name: benzyl alcohols
def: "Compounds containing a phenylmethanol skeleton." []
is_a: CHEBI:33854 ! aromatic alcohol

[Term]
id: CHEBI:22744
name: benzyl group
is_a: CHEBI:33452 ! benzylic group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group
relationship: RO:0018037 CHEBI:17578 ! is substitutent group from toluene

[Term]
id: CHEBI:22750
name: benzylisoquinoline alkaloid
def: "Any isoquinoline alkaloid based on a benzylisoquinoline skeleton." []
is_a: CHEBI:24921 ! isoquinoline alkaloid

[Term]
id: CHEBI:22754
name: berberine alkaloid
is_a: CHEBI:24921 ! isoquinoline alkaloid
is_a: CHEBI:38512 ! dibenzoquinolizine

[Term]
id: CHEBI:22798
name: beta-D-glucoside
def: "Any <small>D</small>-glucoside in which the anomeric centre has β-configuration." []
is_a: CHEBI:35436 ! D-glucoside
is_a: CHEBI:60980 ! beta-glucoside
relationship: RO:0018038 CHEBI:15903 ! has functional parent beta-D-glucose

[Term]
id: CHEBI:228138
name: antinociceptive agent
def: "Any agent that inhibits nociception." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:228209
name: KU-55933
def: "A member of the class of thianthrenes that is thianthrene substituted by a 6-(morpholin-4-yl)-4-oxo-4<em>H</em>-pyran-2-yl group at position 1. It is potent inhibitor of ATM kinase." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131906 ! 4-pyranones
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:64513 ! thianthrenes
relationship: RO:0000087 CHEBI:132992 ! has role radiosensitizing agent
relationship: RO:0000087 CHEBI:138880 ! has role autophagy inducer
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50925 ! has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:22823
name: beta-alanine derivative
is_a: CHEBI:83812 ! non-proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:16958 ! has functional parent beta-alanine

[Term]
id: CHEBI:228364
name: NMR chemical shift reference compound
def: "Any compound that produces a peak used as reference frequency in the δ chemical shift scale." []
is_a: CHEBI:747204 ! reference compound

[Term]
id: CHEBI:228365
name: pemafibrate
def: "A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-amine in which the amino hydrogens are replaced by 3-[(1<i>R</i>)-1-carboxypropoxy]benzyl and 3-(4-methoxyphenoxy)propyl groups. It is a selective peroxisome proliferator-activated receptor (PPAR)-α agonist that is used for the treatment of hyperlipidaemia." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:51548 ! 1,3-benzoxazoles
is_a: CHEBI:51683 ! methoxybenzenes
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35679 ! has role antilipemic drug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:70782 ! has role PPARalpha agonist

[Term]
id: CHEBI:22860
name: amino-acid betaine
def: "Any amino acid-derived zwitterion - such as glycine betaine (<em>N</em>,<em>N</em>,<em>N</em>-trimethylammonioacetate) - in which the ammonium nitrogen carries methyl substituents and bears no hydrogen atoms." []
is_a: CHEBI:35284 ! ammonium betaine
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:22868
name: bile salt
def: "A sodium salt of the conjugate of any bile acid with either glycine or taurine." []
is_a: CHEBI:36078 ! cholanoid
is_a: CHEBI:38700 ! organic sodium salt

[Term]
id: CHEBI:22888
name: biphenyls
def: "Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond." []
is_a: CHEBI:33836 ! benzenoid aromatic compound
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:64459 ! biaryl

[Term]
id: CHEBI:22901
name: bisphenol
def: "By usage, the methylenediphenols, HOC<small><sub>6</sub></small>H<small><sub>4</sub></small>CH<small><sub>2</sub></small>C<small><sub>6</sub></small>H<small><sub>4</sub></small>OH, commonly <em>p</em>,<em>p</em>-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone). The term also includes analogues in the the methylene (or substituted methylene) group has been replaced by a heteroatom." []
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:22907
name: bleomycin
def: "A glycopeptide produced by the bacterium <em>Streptomyces verticillus</em>. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A<small><sub>2</sub></small> and B<small><sub>2</sub></small>." []
is_a: CHEBI:23089 ! chelate-forming peptide
is_a: CHEBI:24396 ! glycopeptide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:22912
name: bornane monoterpenoid
is_a: CHEBI:25409 ! monoterpenoid
relationship: RO:0018040 CHEBI:35783 ! has parent hydride bornane

[Term]
id: CHEBI:22916
name: boron molecular entity
is_a: CHEBI:33581 ! boron group molecular entity
relationship: BFO:0000051 CHEBI:27560 ! has part boron atom

[Term]
id: CHEBI:22917
name: phytogenic insecticide
def: "An insecticide compound naturally occurring in plants." []
is_a: CHEBI:24852 ! insecticide

[Term]
id: CHEBI:22918
name: branched-chain amino acid
def: "Any  amino acid  in which the parent hydrocarbon chain has one or more alkyl substituents" []
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018034 CHEBI:63471 ! is protonated form of branched-chain amino-acid anion

[Term]
id: CHEBI:22921
name: brassinosteroid
is_a: CHEBI:26124 ! phytosteroid

[Term]
id: CHEBI:22923
name: bromate salt
def: "Any salt that has chlorate, [BrO<small><sub>3</sub></small>]<small><sup>−</small></sup>, as the anionic component." []
is_a: CHEBI:24866 ! salt
relationship: BFO:0000051 CHEBI:29223 ! has part bromate

[Term]
id: CHEBI:22925
name: bromide salt
is_a: CHEBI:22928 ! bromine molecular entity
is_a: CHEBI:33958 ! halide salt
relationship: BFO:0000051 CHEBI:15858 ! has part bromide

[Term]
id: CHEBI:22926
name: bromohydrocarbon
def: "A compound derived from a hydrocarbon by replacing a hydrogen atom with a bromine atom." []
is_a: CHEBI:24472 ! halohydrocarbon
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:22927
name: bromine atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24473 ! halogen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:22928
name: bromine molecular entity
is_a: CHEBI:24471 ! halogen molecular entity
relationship: BFO:0000051 CHEBI:22927 ! has part bromine atom

[Term]
id: CHEBI:22929
name: bromoalkane
def: "Any haloalkane that consists of an alkane substituted by at least one bromine atom." []
is_a: CHEBI:24469 ! haloalkane
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:22931
name: bromobisphenol
def: "A bisphenol substituted by at least one bromo group and its derivatives." []
is_a: CHEBI:22901 ! bisphenol
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:22939
name: butanals
def: "An aldehyde based on a butanal skeleton and its substituted derivatives." []
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:22944
name: butanediols
def: "A diol that is a butanediol or a derivative of a butanediol." []
is_a: CHEBI:23824 ! diol

[Term]
id: CHEBI:22951
name: butanone
def: "Any  ketone that is butane substituted by an oxo group at unspecified position." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:229573
name: puerarin(1-)
is_a: CHEBI:20857 ! C-glycosyl compound
is_a: CHEBI:24698 ! hydroxyflavone
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0018033 CHEBI:8633 ! is deprotonated form of puerarin

[Term]
id: CHEBI:22958
name: butenedioic acid
is_a: CHEBI:66873 ! C4-dicarboxylic acid
relationship: RO:0018034 CHEBI:37155 ! is protonated form of hydrogen butenedioate

[Term]
id: CHEBI:22959
name: butenoic acid
def: "Any C<small><sub>4</sub></small>, straight-chain fatty acid containing one double bond." []
is_a: CHEBI:25413 ! monounsaturated fatty acid
is_a: CHEBI:26666 ! short-chain fatty acid
is_a: CHEBI:59202 ! straight-chain fatty acid

[Term]
id: CHEBI:229684
name: fatty amide anion
def: "The conjugate base of a fatty amide, arising from deprotonation of the carboxylic acid group of the corresponding fatty amide." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:29348 ! is deprotonated form of fatty amide

[Term]
id: CHEBI:22977
name: cadmium atom
is_a: CHEBI:33340 ! zinc group element atom

[Term]
id: CHEBI:22978
name: cadmium molecular entity
is_a: CHEBI:33673 ! zinc group molecular entity
relationship: BFO:0000051 CHEBI:22977 ! has part cadmium atom

[Term]
id: CHEBI:22984
name: calcium atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22313 ! alkaline earth metal atom
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient

[Term]
id: CHEBI:22985
name: calcium molecular entity
is_a: CHEBI:33299 ! alkaline earth molecular entity
relationship: BFO:0000051 CHEBI:22984 ! has part calcium atom

[Term]
id: CHEBI:22986
name: calcium ionophore
is_a: CHEBI:24869 ! ionophore

[Term]
id: CHEBI:23000
name: caprolactams
def: "A lactam in which the amide bond is contained within a seven-membered ring, which includes the amide nitrogen and the carbonyl carbon." []
is_a: CHEBI:24995 ! lactam

[Term]
id: CHEBI:23003
name: carbamate ester
def: "Any ester of carbamic acid or its <em>N</em>-substituted derivatives." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:28616 ! has functional parent carbamic acid

[Term]
id: CHEBI:23004
name: carbamoyl group
def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." []
is_a: CHEBI:27207 ! univalent carboacyl group
relationship: RO:0018037 CHEBI:28616 ! is substitutent group from carbamic acid

[Term]
id: CHEBI:23007
name: carbohydrate-containing antibiotic
def: "Any carbohydrate derivative that exhibits antibiotic activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:23012
name: carbon disulfide
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:64708 ! one-carbon compound

[Term]
id: CHEBI:23014
name: carbon oxide
is_a: CHEBI:25701 ! organic oxide
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:23016
name: carbonates
def: "Organooxygen compounds that are salts or esters of carbonic acid, H<small><sub>2</sub></small>CO<small><sub>3</sub></small>." []
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0018038 CHEBI:28976 ! has functional parent carbonic acid

[Term]
id: CHEBI:23018
name: EC 4.2.1.1 (carbonic anhydrase) inhibitor
def: "An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H<small><sup>+</small></sup> ions by the proximal kidney tubule." []
is_a: CHEBI:76907 ! EC 4.2.1.* (hydro-lyases) inhibitor

[Term]
id: CHEBI:23019
name: carbonyl group
is_a: CHEBI:51422 ! organodiyl group

[Term]
id: CHEBI:23042
name: carotene
def: "Hydrocarbon carotenoids." []
is_a: CHEBI:35193 ! tetraterpene

[Term]
id: CHEBI:23044
name: carotenoid
def: "One of a class of tetraterpenoids (C<small><sub>40</sub></small>), formally derived from the acyclic parent, ψ,ψ-carotene by hydrogenation, dehydrogenation, cyclization, oxidation, or combination of these processes. This class includes carotenes, xanthophylls and certain compounds that arise from rearrangement of the skeleton of ψ,ψ-carotene or by loss of part of this structure. Retinoids are excluded." []
is_a: CHEBI:26935 ! tetraterpenoid
relationship: RO:0018040 CHEBI:23042 ! has parent hydride carotene

[Term]
id: CHEBI:23045
name: carotenol
is_a: CHEBI:27325 ! xanthophyll

[Term]
id: CHEBI:230471
name: EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor
def: "A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-β-glucan synthase (EC 2.4.1.34)." []
is_a: CHEBI:76789 ! EC 2.4.1.* (hexosyltransferase) inhibitor

[Term]
id: CHEBI:230497
name: PLX5622
def: "PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor. PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. PLX5622 is mostly used in the way of feed free diet." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:46771 ! pyrrolopyridine
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug

[Term]
id: CHEBI:23053
name: catechin
def: "Members of the class of hydroxyflavan that have a flavan-3-ol skeleton and its substituted derivatives." []
is_a: CHEBI:72010 ! hydroxyflavan

[Term]
id: CHEBI:23066
name: cephalosporin
def: "A class of β-lactam antibiotics differing from the penicillins in having a 6-membered, rather than a 5-membered, side ring.  Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy." []
is_a: CHEBI:38311 ! cephem
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:23079
name: cerebroside
def: "Any member of a group of glycosphingolipids, also known as monoglycosylceramides, which are important components in animal muscle and nerve cell membranes." []
is_a: CHEBI:17761 ! ceramide
is_a: CHEBI:25513 ! neutral glycosphingolipid

[Term]
id: CHEBI:23089
name: chelate-forming peptide
is_a: CHEBI:25903 ! peptide antibiotic
relationship: RO:0000087 CHEBI:38161 ! has role chelator

[Term]
id: CHEBI:23092
name: chemosterilant
def: "A substance intended to sterilize any organism." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:23100
name: chitin synthesis inhibitor
is_a: CHEBI:24851 ! insect growth regulator

[Term]
id: CHEBI:23104
name: chitooligosaccharide
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:23114
name: chloride salt
is_a: CHEBI:23117 ! chlorine molecular entity
is_a: CHEBI:33958 ! halide salt
relationship: BFO:0000051 CHEBI:17996 ! has part chloride

[Term]
id: CHEBI:23115
name: chlorohydrocarbon
def: "A compound derived from a hydrocarbon by replacing at least one hydrogen atom with a chlorine atom." []
is_a: CHEBI:24472 ! halohydrocarbon
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:23116
name: chlorine atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24473 ! halogen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:23117
name: chlorine molecular entity
def: "A halogen molecular entity containing one or more atoms of chlorine." []
is_a: CHEBI:24471 ! halogen molecular entity
relationship: BFO:0000051 CHEBI:23116 ! has part chlorine atom

[Term]
id: CHEBI:231209
name: Pyrazolopyrimidinone
is_a: CHEBI:38669 ! pyrazolopyrimidine

[Term]
id: CHEBI:23123
name: chloroacetate
def: "A haloacetate(1−) resulting from the deprotonation of the carboxy group of chloroacetic acid." []
is_a: CHEBI:85638 ! haloacetate(1-)
relationship: RO:0018033 CHEBI:27869 ! is deprotonated form of chloroacetic acid

[Term]
id: CHEBI:23128
name: chloroalkane
def: "Any haloalkane that consists of an alkane substituted by at least one chloro group." []
is_a: CHEBI:24469 ! haloalkane
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:23130
name: chloroaniline
def: "Any  substituted aniline carrying at least one chloro group." []
is_a: CHEBI:23132 ! chlorobenzenes
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:23132
name: chlorobenzenes
def: "Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:23133
name: chlorobenzoate
def: "Any member of the class of benzoates in which the benzene ring is substituted by at least one chloro group." []
is_a: CHEBI:22718 ! benzoates
relationship: RO:0018033 CHEBI:23134 ! is deprotonated form of chlorobenzoic acid

[Term]
id: CHEBI:23134
name: chlorobenzoic acid
def: "Any member of the class of benzoic acids in which the benzene ring is substituted by at least one chloro group." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:36685 ! chlorocarboxylic acid
relationship: RO:0018034 CHEBI:23133 ! is protonated form of chlorobenzoate

[Term]
id: CHEBI:231342
name: ceralasertib
def: "Ceralasertib is an orally available morpholino-pyrimidine-based inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase, with potential antineoplastic activity. Upon oral administration, Ceralasertib selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:23135
name: chlorobenzophenone
def: "A member of the class of benzophenones that is any substituted benzophenone in which at least one of the substituents is a chlorine." []
is_a: CHEBI:22726 ! benzophenones
is_a: CHEBI:23132 ! chlorobenzenes

[Term]
id: CHEBI:23141
name: chloroethanol
def: "An organochlorine compound that is ethanol substituted by at least one chloro group." []
is_a: CHEBI:23982 ! ethanols
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:23142
name: chloroethenes
def: "A chloroalkene that is ethene in which one or more of the hydrogens has been replaced by chlorine." []
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:36387 ! chloroalkene
is_a: CHEBI:51316 ! haloethene

[Term]
id: CHEBI:231424
name: (S)-tolvaptan
def: "The (<i>S</i>)-enantiomer of tolvaptan." []
is_a: CHEBI:231425 ! N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
relationship: RO:0018039 CHEBI:231426 ! is enantiomer of (R)-tolvaptan

[Term]
id: CHEBI:231425
name: N-\{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl\}-2-methylbenzamide
def: "A member of the class of benzazepines that is 2,3,4,5-tetrahydro-1<em>H</em>-1-benzazepine substituted by 2-methyl-4-(2-methylbenzamido)benzoyl, hydroxy, and chloro groups at positions 1, 5, and 7, respectively." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:35676 ! benzazepine
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:231426
name: (R)-tolvaptan
def: "The (<i>R</i>)-enantiomer of tolvaptan." []
is_a: CHEBI:231425 ! N-{4-[(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
relationship: RO:0018039 CHEBI:231424 ! is enantiomer of (S)-tolvaptan

[Term]
id: CHEBI:23148
name: chloromethanes
def: "A halomethane that is methane in which one or more hydrogens has been replaced by chlorine." []
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:23128 ! chloroalkane
is_a: CHEBI:39279 ! halomethane

[Term]
id: CHEBI:23150
name: chlorophenol
def: "A halophenol that is any phenol containing one or more covalently bonded chlorine atoms." []
is_a: CHEBI:23132 ! chlorobenzenes
is_a: CHEBI:38856 ! halophenol

[Term]
id: CHEBI:23151
name: chlorophenoxyacetate anion
def: "A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any chlorophenoxyacetic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018038 CHEBI:38846 ! has functional parent phenoxyacetate

[Term]
id: CHEBI:23152
name: chlorophenoxyacetic acid
def: "A monocarboxylic acid that is phenoxyacetic acid in which at least one of the phenyl hydrogens is replaced by chlorine." []
is_a: CHEBI:23132 ! chlorobenzenes
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0018038 CHEBI:8075 ! has functional parent phenoxyacetic acid

[Term]
id: CHEBI:23154
name: chlorophenylethane
def: "Any  chlorohydrocarbon that is phenylethane substituted by at least one chloro group at unspecified position." []
is_a: CHEBI:23115 ! chlorohydrocarbon

[Term]
id: CHEBI:231540
name: nucleotide derivative
def: "A nucleoside phosphate that is derived from a nucleotide." []
is_a: CHEBI:25608 ! nucleoside phosphate
relationship: RO:0018038 CHEBI:36976 ! has functional parent nucleotide

[Term]
id: CHEBI:231547
name: unsaturated fatty aldehyde
def: "Any fatty aldehyde containing at least one C=C or C≡C bond." []
is_a: CHEBI:35746 ! fatty aldehyde
relationship: RO:0018038 CHEBI:27208 ! has functional parent unsaturated fatty acid

[Term]
id: CHEBI:23155
name: chlorophenylethylene
def: "A chlorohydrocarbon that is consists of ethylene in which one or more hydrogens are replaced by chlorophenyl groups." []
is_a: CHEBI:23115 ! chlorohydrocarbon

[Term]
id: CHEBI:231550
name: azithromycin(2+)
def: "A tertiary ammonium ion resulting from the protonation of the two amino groups of azithromycin; major species at pH 7.3." []
is_a: CHEBI:137982 ! tertiary ammonium ion
relationship: RO:0018034 CHEBI:2955 ! is protonated form of azithromycin

[Term]
id: CHEBI:231553
name: levofloxacin(1-)
def: "An oxo monocarboxylic acid anion that is the conjugate base of levofloxacin resulting from the deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:35902 ! oxo monocarboxylic acid anion
relationship: RO:0018033 CHEBI:63598 ! is deprotonated form of levofloxacin

[Term]
id: CHEBI:231554
name: flumetnicam
def: "A pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4. It is a metabolite of flonicamid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140324 ! primary carboxamide
is_a: CHEBI:25529 ! pyridinecarboxamide
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0018038 CHEBI:17154 ! has functional parent nicotinamide

[Term]
id: CHEBI:23156
name: chlorophenylmethane
def: "A chlorohydrocarbon that is phenylmethane substituted by a chloro group at unspecified position." []
is_a: CHEBI:23115 ! chlorohydrocarbon

[Term]
id: CHEBI:231594
name: 17-ethynyl-17-hydroxy-18a-homoestr-4-en-3-one
def: "A 3-oxo-Δ<small><sup>4</small></sup> steroid that is gon-4-en-3-one that carries ethyl, hydroxy, and ethynyl groups at positions 13, 17 and 17, respectively." []
is_a: CHEBI:36838 ! 17-hydroxy steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:73477 ! terminal acetylenic compound

[Term]
id: CHEBI:231598
name: tazemetostat
def: "Tazemetostat is a methyltransferase inhibitor used to treat metastatic or locally advanced epithelioid sarcoma not eligible for complete resection." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:231601
name: trastuzumab
def: "Trastuzumab is a HER2/neu Receptor Antagonist." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:231609
name: (4-chloro-2-methylphenoxy)acetate
is_a: CHEBI:23151 ! chlorophenoxyacetate anion
relationship: RO:0018033 CHEBI:50099 ! is deprotonated form of (4-chloro-2-methylphenoxy)acetic acid

[Term]
id: CHEBI:231614
name: Nivolumab
def: "Nivolumab is a human monoclonal antibody for Programmed Death Receptor-1 (PD-1). It is a targeted immunotherapy treatment against metastatic cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent

[Term]
id: CHEBI:231618
name: 4-hydroxytamoxifen
def: "4-hydroxytamoxifen is a selective estrogen receptor modulator. It is currently in the development process to work as a potential breast hyperplasia treatment." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:23162
name: chloropropene
def: "Any chloroalkene that is propene substituted by at least one chloro group at unspecified position." []
is_a: CHEBI:36387 ! chloroalkene

[Term]
id: CHEBI:231684
name: MCC950
def: "A member of the class of <em>s</em>-indacenes that is 1,2,3,5,6,7-hexahydro-<em>s</em>-indacene substituted by a ({[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonyl}carbamoyl)amino group at position 4. It is a potent and selective NLRP3 inhibitor." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24129 ! furans
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:51125 ! s-indacenes
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:231916 ! has role NLRP3 inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:231853
name: gold cation
def: "Any gold ion that is positively charged." []
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:33970 ! elemental gold

[Term]
id: CHEBI:231854
name: caesium cation
def: "Any caesium ion that is positively charged." []
is_a: CHEBI:33504 ! alkali metal cation
is_a: CHEBI:60270 ! caesium ion

[Term]
id: CHEBI:231855
name: gallium cation
def: "Any gallium ion that is positively charged." []
is_a: CHEBI:155920 ! elemental gallium
is_a: CHEBI:25213 ! metal cation

[Term]
id: CHEBI:231911
name: renoprotective agent
def: "Any compound that is able to prevent damage to the kidneys." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:231916
name: NLRP3 inhibitor
def: "Any inhibitor of NLRP3." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:23213
name: choline ester
is_a: CHEBI:35701 ! ester
relationship: RO:0018038 CHEBI:15354 ! has functional parent choline

[Term]
id: CHEBI:232159
name: silmitasertib
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:23217
name: cholines
def: "A quaternary ammonium ion based on the choline ion and its substituted derivatives thereof." []
is_a: CHEBI:35267 ! quaternary ammonium ion

[Term]
id: CHEBI:23219
name: bile acid taurine conjugate
def: "A bile acid conjugate resulting from the formal condensation of a bile acid with the amino group of taurine." []
is_a: CHEBI:36249 ! bile acid conjugate
relationship: RO:0018038 CHEBI:15891 ! has functional parent taurine

[Term]
id: CHEBI:23229
name: chromanol
def: "Any member of the class of chromanes that is chromane substituted by one or more hydroxy groups." []
is_a: CHEBI:23230 ! chromanes
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:23230
name: chromanes
is_a: CHEBI:38443 ! 1-benzopyran

[Term]
id: CHEBI:23232
name: chromenes
is_a: CHEBI:38443 ! 1-benzopyran

[Term]
id: CHEBI:23237
name: chromium molecular entity
is_a: CHEBI:33741 ! chromium group molecular entity
relationship: BFO:0000051 CHEBI:28073 ! has part chromium atom

[Term]
id: CHEBI:232380
name: Mdivi-1
is_a: CHEBI:38530 ! quinazolines

[Term]
id: CHEBI:23239
name: chromopeptide
is_a: CHEBI:25903 ! peptide antibiotic

[Term]
id: CHEBI:23240
name: chromophore
def: "The part (atom or group of atoms) of a molecular entity in which the electronic transition responsible for a given spectral band is approximately localized." []
is_a: CHEBI:52215 ! photochemical role

[Term]
id: CHEBI:232424
name: MitoTEMPO
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36094 ! organic chloride salt
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger

[Term]
id: CHEBI:232436
name: calcium chelator
def: "A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central calcium atom at two or more points." []
is_a: CHEBI:38161 ! chelator

[Term]
id: CHEBI:23245
name: cinnamaldehydes
def: "An  enal based on a cinnamaldehyde skeleton and its substituted derivatives." []
is_a: CHEBI:51688 ! enal

[Term]
id: CHEBI:23252
name: cinnamic acids
def: "Any α,β-unsaturated monocarboxylic acid based on the cinnamic acid skeleton and its substituted derivatives." []
is_a: CHEBI:78840 ! olefinic compound
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid

[Term]
id: CHEBI:232521
name: CB-5083
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35222 ! has role inhibitor

[Term]
id: CHEBI:232543
name: epirubicin hydrochloride
is_a: CHEBI:48120 ! anthracycline
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:232547
name: etomoxir
def: "(+)-Etomoxir sodium salt is a chiral compound that functions as a reversible inhibitor of carnitine palmitoyltransferase I (CPT-1)." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:233088
name: spermidine trihydrochloride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:61908 ! has role EC 1.14.13.39 (nitric oxide synthase) inhibitor
relationship: RO:0018038 CHEBI:16610 ! has functional parent spermidine

[Term]
id: CHEBI:233143
name: MnTBAP
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:78152 ! has role enzyme mimic

[Term]
id: CHEBI:23324
name: citrullines
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid

[Term]
id: CHEBI:233321
name: Mitoquinone
def: "Mitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to a thousand fold." []
is_a: CHEBI:16389 ! ubiquinones
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent

[Term]
id: CHEBI:233323
name: DTAGv-1
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:23334
name: cobalamins
is_a: CHEBI:176843 ! vitamin B12
is_a: CHEBI:23341 ! cobamides

[Term]
id: CHEBI:233359
name: AZD4573
def: "AZD4573 is a potent and highly selective CDK9 inhibitor (IC50 of less than 4 nM) that enables transient target engagement for the treatment of hematologic malignancies." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018038 CHEBI:33707 ! has functional parent gamma-amino acid

[Term]
id: CHEBI:23336
name: cobalt cation
is_a: CHEBI:33515 ! transition element cation

[Term]
id: CHEBI:233361
name: GSK864
def: "GSK864 is an isocitrate dehydrogenase 1 (IDH1) mutant inhibitor; inhibits IDH1 mutants R132C, R132H, and R132G with IC50 values of 8.8, 15.2 and 16.6 nM." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:23341
name: cobamides
is_a: CHEBI:23390 ! cobalt-corrinoid hexaamide

[Term]
id: CHEBI:233423
name: antifibrotic agent
def: "Any agent which acts to reduce fibrosis." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:233443
name: N-acetyl-L-alpha-amino acid anion
is_a: CHEBI:59874 ! N-acyl-L-alpha-amino acid anion

[Term]
id: CHEBI:233500
name: post-transition metal atom
def: "A group of metal atoms that are located in the periodic table between transition metals and metalloids." []
is_a: CHEBI:33521 ! metal atom

[Term]
id: CHEBI:23354
name: coenzyme
def: "A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons." []
is_a: CHEBI:23357 ! cofactor

[Term]
id: CHEBI:233559
name: N-carbamoylglutamate(2-)
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0018033 CHEBI:86349 ! is deprotonated form of N-carbamoylglutamic acid

[Term]
id: CHEBI:23357
name: cofactor
def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:23359
name: colchicine
def: "An  alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[<em>a</em>]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus <em>Colchicum</em>." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38032 ! carbotricyclic compound
relationship: RO:0000087 CHEBI:61951 ! has role microtubule-destabilising agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:233645
name: 4-Octyl itaconate
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:23366
name: compatible osmolytes
is_a: CHEBI:25728 ! osmolyte

[Term]
id: CHEBI:23367
name: molecular entity
def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." []
is_a: CHEBI:24431 ! chemical entity

[Term]
id: CHEBI:23377
name: copper molecular entity
is_a: CHEBI:33745 ! copper group molecular entity
relationship: BFO:0000051 CHEBI:28694 ! has part copper atom

[Term]
id: CHEBI:23378
name: copper cation
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:37404 ! elemental copper
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:233869
name: 4-(phenylazo)aniline
def: "Azobenzene substituted at one of the 4-positions by an amino group. It has a role as a dye and an allergen." []
is_a: CHEBI:22682 ! azobenzenes
is_a: CHEBI:50471 ! primary arylamine
relationship: RO:0000087 CHEBI:37958 ! has role dye
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0018038 CHEBI:190358 ! has functional parent azobenzene

[Term]
id: CHEBI:23390
name: cobalt-corrinoid hexaamide
is_a: CHEBI:33906 ! cobalt corrinoid

[Term]
id: CHEBI:23401
name: coumaric acid
def: "A monohydroxycinnamic acid that is prop-2-enoic acid substituted by a hydroxyphenyl group at position 3." []
is_a: CHEBI:24688 ! monohydroxycinnamic acid

[Term]
id: CHEBI:23403
name: coumarins
is_a: CHEBI:26004 ! phenylpropanoid
is_a: CHEBI:38445 ! chromenone

[Term]
id: CHEBI:234135
name: deoxyartemisinin
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:23414
name: copper(II) sulfate
def: "A metal sulfate compound having copper(2+) as the metal ion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51336 ! metal sulfate
relationship: BFO:0000051 CHEBI:29036 ! has part copper(2+)
relationship: RO:0000087 CHEBI:139492 ! has role sensitiser
relationship: RO:0000087 CHEBI:149552 ! has role emetic
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer

[Term]
id: CHEBI:23423
name: pseudohalogen oxoacid
is_a: CHEBI:24833 ! oxoacid

[Term]
id: CHEBI:23424
name: cyanides
def: "Salts and <em>C</em>-organyl derivatives of hydrogen cyanide, HC≡N." []
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0018040 CHEBI:18407 ! has parent hydride hydrogen cyanide

[Term]
id: CHEBI:23437
name: cyanohydrin
def: "An α-hydroxynitrile resulting from the formal addition of hydrogen cyanide to the C=O bond of an aldehyde or ketone." []
is_a: CHEBI:22455 ! alpha-hydroxynitrile

[Term]
id: CHEBI:23438
name: cyanopyridine
def: "Any pyridine carrying at least one cyano substituent." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:234429
name: mitoquinone mesylate
is_a: CHEBI:16389 ! ubiquinones
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:23443
name: cyclic amide
is_a: CHEBI:32988 ! amide

[Term]
id: CHEBI:23446
name: cyclic monoterpene ketone
def: "A cyclic terpene ketone in which the terpene specified is monoterpene." []
is_a: CHEBI:25408 ! monoterpene ketone
is_a: CHEBI:36130 ! cyclic terpene ketone

[Term]
id: CHEBI:23447
name: cyclic nucleotide
is_a: CHEBI:36976 ! nucleotide

[Term]
id: CHEBI:23448
name: cyclic oligosaccharide
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:23449
name: cyclic peptide
is_a: CHEBI:16670 ! peptide

[Term]
id: CHEBI:23451
name: cyclitol
def: "A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom." []
is_a: CHEBI:26191 ! polyol

[Term]
id: CHEBI:23453
name: cycloalkane
def: "Saturated monocyclic hydrocarbons (with or without side chains)." []
is_a: CHEBI:33654 ! alicyclic compound
is_a: CHEBI:33664 ! monocyclic hydrocarbon

[Term]
id: CHEBI:234554
name: urolithin
def: "A benzochromenone that is 6<em>H</em>-benzo[<i>c</i>]chromen-6-one with at least one hydrogen atom of the benzene rings substituted by an hydroxyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23403 ! coumarins
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:64986 ! benzochromenone
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0018038 CHEBI:86511 ! has functional parent 6H-dibenzo[b,d]pyran-6-one

[Term]
id: CHEBI:23456
name: cyclodextrin
def: "A macrocycle composed of five or more <small>D</small>-glucopyranose units bonded via (1→4)-linkages." []
is_a: CHEBI:17623 ! cyclomaltodextrin
is_a: CHEBI:51026 ! macrocycle

[Term]
id: CHEBI:23457
name: cyclodiene organochlorine insecticide
def: "A sub-category of organochlorine insecticides, the members of which are all derived from hexachlorocyclopentadiene. They possess a structure based on two 3-dimensional carbon ring units, one of which is heavily chlorinated." []
is_a: CHEBI:25705 ! organochlorine insecticide

[Term]
id: CHEBI:23480
name: cyclohexanols
def: "An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton." []
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:23482
name: cyclohexanones
def: "Any alicyclic ketone based on a cyclohexane skeleton and its substituted derivatives thereof." []
is_a: CHEBI:36132 ! alicyclic ketone

[Term]
id: CHEBI:23483
name: cyclohexenecarboxylic acid
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0018034 CHEBI:36126 ! is protonated form of cyclohexenecarboxylate

[Term]
id: CHEBI:23492
name: cyclopentane
def: "A cycloalkane that consists of five carbons each bonded with two hydrogens above and below the plane. The parent of the class of cyclopentanes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:23453 ! cycloalkane
is_a: CHEBI:23493 ! cyclopentanes
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent

[Term]
id: CHEBI:23493
name: cyclopentanes
def: "Cyclopentane and its derivatives formed by substitution." []
is_a: CHEBI:33598 ! carbocyclic compound

[Term]
id: CHEBI:23495
name: cyclopentanols
def: "An alcohol in which one or more hydroxy groups are attached to a cyclopentane skeleton." []
is_a: CHEBI:23493 ! cyclopentanes
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:23500
name: cyclopropanecarboxylic acid
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:51454 ! cyclopropanes
relationship: RO:0018034 CHEBI:36128 ! is protonated form of cyclopropanecarboxylate

[Term]
id: CHEBI:23509
name: cysteine derivative
def: "An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:15356 ! has functional parent cysteine

[Term]
id: CHEBI:23521
name: cytidine 5'-phosphate
is_a: CHEBI:23523 ! cytidine phosphate

[Term]
id: CHEBI:23523
name: cytidine phosphate
is_a: CHEBI:25608 ! nucleoside phosphate
relationship: RO:0018038 CHEBI:16040 ! has functional parent cytosine

[Term]
id: CHEBI:23524
name: cytidines
is_a: CHEBI:39446 ! pyrimidine ribonucleosides
relationship: RO:0018038 CHEBI:16040 ! has functional parent cytosine

[Term]
id: CHEBI:23527
name: cytochalasin B
def: "An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23528 ! cytochalasin
is_a: CHEBI:24995 ! lactam
is_a: CHEBI:25000 ! lactone
is_a: CHEBI:26979 ! organic heterotricyclic compound
relationship: RO:0000087 CHEBI:25442 ! has role mycotoxin
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:70728 ! has role actin polymerisation inhibitor

[Term]
id: CHEBI:23528
name: cytochalasin
is_a: CHEBI:24897 ! isoindoles

[Term]
id: CHEBI:23529
name: cytochrome-b6f complex inhibitor
is_a: CHEBI:26087 ! photosynthetic electron-transport chain inhibitor

[Term]
id: CHEBI:23530
name: cytokinin
def: "A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots." []
is_a: CHEBI:37848 ! plant hormone

[Term]
id: CHEBI:235319
name: Pervanadate
def: "trisodium;hydrogen peroxide;trioxido(oxo)vanadium" []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:235343
name: ellagic acid(2-)
is_a: CHEBI:38163 ! organic heterotetracyclic compound
relationship: RO:0018033 CHEBI:4775 ! is deprotonated form of ellagic acid

[Term]
id: CHEBI:23582
name: defoliant
def: "A herbicide which when sprayed or dusted on plants causes its leaves to fall off." []
is_a: CHEBI:24527 ! herbicide

[Term]
id: CHEBI:23614
name: deoxycholate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131878 ! cholanic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28834 ! is deprotonated form of deoxycholic acid

[Term]
id: CHEBI:23622
name: deoxygalactose
is_a: CHEBI:23628 ! deoxyhexose

[Term]
id: CHEBI:23623
name: deoxyglucose
def: "A deoxyhexose comprising glucose having at least one hydroxy group replaced by hydrogen." []
is_a: CHEBI:23628 ! deoxyhexose

[Term]
id: CHEBI:23628
name: deoxyhexose
def: "Any C<small><sub>6</sub></small> deoxy sugar having at least one hydroxy group replaced by hydrogen." []
is_a: CHEBI:23639 ! deoxy sugar
is_a: CHEBI:33917 ! aldohexose

[Term]
id: CHEBI:23636
name: deoxyribonucleoside
is_a: CHEBI:33838 ! nucleoside

[Term]
id: CHEBI:23639
name: deoxy sugar
def: "Any sugar having a hydroxy group replaced with a hydrogen atom." []
is_a: CHEBI:16646 ! carbohydrate

[Term]
id: CHEBI:23643
name: depsipeptide
def: "A natural or synthetic compound having a sequence of amino and hydroxy carboxylic acid residues (usually α-amino and α-hydroxy acids), commonly but not necessarily regularly alternating." []
is_a: CHEBI:16670 ! peptide

[Term]
id: CHEBI:23666
name: diamine
def: "Any polyamine that contains two amino groups." []
is_a: CHEBI:88061 ! polyamine

[Term]
id: CHEBI:23677
name: diazole
def: "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." []
is_a: CHEBI:68452 ! azole

[Term]
id: CHEBI:23690
name: dicarboxylic acid amide
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:23696
name: dichloroaniline
is_a: CHEBI:23130 ! chloroaniline
is_a: CHEBI:23697 ! dichlorobenzene

[Term]
id: CHEBI:23697
name: dichlorobenzene
def: "Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions." []
is_a: CHEBI:23132 ! chlorobenzenes

[Term]
id: CHEBI:23702
name: dichlorophenol
def: "Any chlorophenol carrying chloro substituents." []
is_a: CHEBI:23150 ! chlorophenol
is_a: CHEBI:23697 ! dichlorobenzene

[Term]
id: CHEBI:23704
name: diepoxybutane
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32955 ! epoxide
relationship: RO:0000087 CHEBI:25435 ! has role mutagen

[Term]
id: CHEBI:23763
name: pyrroline
def: "Any organic heteromonocyclic compound with a structure based on a dihydropyrrole." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:23765
name: quinolone
is_a: CHEBI:26513 ! quinolines

[Term]
id: CHEBI:23775
name: dihydroxy-5beta-cholanic acid
def: "A hydroxy-5β-cholanic acid carrying two hydroxy groups at unspecified positions." []
is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid
is_a: CHEBI:85184 ! dihydroxycholanic acid

[Term]
id: CHEBI:23778
name: dihydroxybenzoic acid
def: "Any member of the class of  hydroxybenzoic acids carrying  two phenolic hydroxy groups on the benzene ring and its derivatives." []
is_a: CHEBI:24676 ! hydroxybenzoic acid
relationship: RO:0018034 CHEBI:36084 ! is protonated form of dihydroxybenzoate

[Term]
id: CHEBI:237958
name: (\{[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato\}oxy)(phosphonatooxy)phosphinate
is_a: CHEBI:37045 ! purine ribonucleoside 5'-triphosphate
is_a: CHEBI:37096 ! adenosine 5'-phosphate
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0018034 CHEBI:57299 ! is protonated form of ATP(3-)

[Term]
id: CHEBI:23798
name: dimethoxyflavone
def: "Any methoxyflavone with two methoxy substituents." []
is_a: CHEBI:25241 ! methoxyflavone

[Term]
id: CHEBI:23806
name: dimethylaniline
def: "A methylaniline carrying at least two methyl groups." []
is_a: CHEBI:25275 ! methylaniline

[Term]
id: CHEBI:23822
name: dinitrotoluene
def: "Any  nitrotoluene carrying two nitro substituents." []
is_a: CHEBI:25566 ! nitrotoluene

[Term]
id: CHEBI:23824
name: diol
def: "A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols." []
is_a: CHEBI:26191 ! polyol

[Term]
id: CHEBI:23825
name: dibenzodioxine
def: "Oxanthrene (formerly dibenzo[<em>b</em>,<em>e</em>][1,4]dioxine) and its derivatives." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:27171 ! organic heterobicyclic compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic

[Term]
id: CHEBI:23843
name: disaccharide phosphate
is_a: CHEBI:26816 ! carbohydrate phosphate
is_a: CHEBI:63353 ! disaccharide derivative

[Term]
id: CHEBI:23849
name: diterpenoid
def: "Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." []
is_a: CHEBI:26873 ! terpenoid
relationship: RO:0018040 CHEBI:35190 ! has parent hydride diterpene

[Term]
id: CHEBI:23853
name: dithiol
is_a: CHEBI:29256 ! thiol

[Term]
id: CHEBI:23870
name: dodecyl group
is_a: CHEBI:22323 ! alkyl group
relationship: RO:0018037 CHEBI:28817 ! is substitutent group from dodecane

[Term]
id: CHEBI:23872
name: dodecyl sulfate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58958 ! organosulfate oxoanion
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0018033 CHEBI:45599 ! is deprotonated form of dodecyl hydrogen sulfate

[Term]
id: CHEBI:23888
name: drug
def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." []
is_a: CHEBI:52217 ! pharmaceutical

[Term]
id: CHEBI:23891
name: ecdysone antagonists
is_a: CHEBI:24851 ! insect growth regulator

[Term]
id: CHEBI:23897
name: ecdysteroid
def: "A class of steroids that include insect moulting and sex hormones." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35341 ! steroid
relationship: RO:0000087 CHEBI:24621 ! has role hormone

[Term]
id: CHEBI:23899
name: icosanoid
def: "Any member of the group of signalling molecules arising from oxidation of the three C<small><sub>20</sub></small> essential fatty acids (EFAs) icosapentaenoic acid (EPA), arachidonic acid (AA) and dihomo-gamma-linolenic acid (DGLA)." []
is_a: CHEBI:61697 ! fatty acid derivative
relationship: RO:0018034 CHEBI:62937 ! is protonated form of icosanoid anion

[Term]
id: CHEBI:23905
name: monoatomic anion
is_a: CHEBI:22563 ! anion
is_a: CHEBI:24867 ! monoatomic ion

[Term]
id: CHEBI:23906
name: monoatomic cation
is_a: CHEBI:24867 ! monoatomic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:23924
name: enzyme inhibitor
def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:2394
name: acetochlor
def: "A monocarboxylic acid amide that is <em>N</em>-phenylacetamide carrying an ethyl and a methyl group at positions 2 and 6 respectively on the benzene ring while one of the methyl hydrogens as well as the hydrogen attached to the nitrogen atom have been replaced by a chloro and an ethoxymethyl group respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:28884 ! has functional parent N-phenylacetamide

[Term]
id: CHEBI:23953
name: erythromycins
is_a: CHEBI:25105 ! macrolide antibiotic
relationship: RO:0018038 CHEBI:23955 ! has functional parent erythronolide

[Term]
id: CHEBI:23955
name: erythronolide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25106 ! macrolide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:23965
name: estradiol
def: "A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:177917 ! phenolic steroid
is_a: CHEBI:36838 ! 17-hydroxy steroid
relationship: RO:0000087 CHEBI:50114 ! has role estrogen
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018040 CHEBI:23966 ! has parent hydride estrane

[Term]
id: CHEBI:23966
name: estrane
is_a: CHEBI:35508 ! steroid fundamental parent

[Term]
id: CHEBI:23976
name: ethanediol
def: "Any diol that is ethane or substituted ethane carrying two hydroxy groups." []
is_a: CHEBI:23824 ! diol

[Term]
id: CHEBI:23981
name: ethanolamines
is_a: CHEBI:22478 ! amino alcohol

[Term]
id: CHEBI:23982
name: ethanols
def: "Any primary alcohol based on an ethanol skeleton." []
is_a: CHEBI:15734 ! primary alcohol

[Term]
id: CHEBI:23990
name: ethyl ester
def: "Any carboxylic ester resulting from the formal condensation of the carboxy group of a carboxylic acid with ethanol." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:16236 ! has functional parent ethanol
relationship: RO:0018038 CHEBI:33575 ! has functional parent carboxylic acid

[Term]
id: CHEBI:23995
name: N-ethyl-N-nitrosourea
def: "A member of the class of <em>N</em>-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:76551 ! N-nitrosoureas
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:23996
name: ethyl sulfide
def: "An aliphatic sulfide in which the sulfur atom is bonded to at least one ethyl group." []
is_a: CHEBI:22327 ! aliphatic sulfide

[Term]
id: CHEBI:24002
name: ethylene releasers
is_a: CHEBI:26155 ! plant growth regulator

[Term]
id: CHEBI:24020
name: fat-soluble vitamin (role)
def: "Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess." []
is_a: CHEBI:33229 ! vitamin (role)

[Term]
id: CHEBI:24026
name: fatty alcohol
def: "An aliphatic alcohol consisting of a chain of 3 to greater than 27 carbon atoms. Fatty alcohols may be saturated or unsaturated and may be branched or unbranched." []
is_a: CHEBI:30879 ! alcohol
is_a: CHEBI:61697 ! fatty acid derivative

[Term]
id: CHEBI:24028
name: iron(3+) chelator
is_a: CHEBI:38157 ! iron chelator

[Term]
id: CHEBI:24031
name: ferulic acids
is_a: CHEBI:24688 ! monohydroxycinnamic acid
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:24043
name: flavones
def: "A member of the class of flavonoid with a 2-aryl-1-benzopyran-4-one (2-arylchromen-4-one) skeleton and its substituted derivatives." []
is_a: CHEBI:192499 ! anthoxanthin

[Term]
id: CHEBI:24059
name: fluorenes
def: "An <em>ortho</em>-fused polycyclic arene in which the skeleton is composed of two benzene rings <em>ortho</em>-fused to cyclopentane." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38032 ! carbotricyclic compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0018040 CHEBI:28266 ! has parent hydride fluorene

[Term]
id: CHEBI:24060
name: fluoride salt
is_a: CHEBI:24062 ! fluorine molecular entity
is_a: CHEBI:33958 ! halide salt
relationship: BFO:0000051 CHEBI:17051 ! has part fluoride

[Term]
id: CHEBI:24061
name: fluorine atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24473 ! halogen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:24062
name: fluorine molecular entity
is_a: CHEBI:24471 ! halogen molecular entity
relationship: BFO:0000051 CHEBI:24061 ! has part fluorine atom

[Term]
id: CHEBI:24067
name: fluoroalkane
def: "A haloalkane that is an alkane in which at least one hydrogen atom has been replaced by a fluorine atom." []
is_a: CHEBI:24469 ! haloalkane
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:24068
name: fluoroamino acid
def: "An organofluorine compound that consists of an amino acid substituted by a fluoro group." []
is_a: CHEBI:24470 ! haloamino acid
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:24079
name: formamides
def: "Amides with the general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>NCHO (R<small><sup>1</small></sup> and R<small><sup>2</small></sup> can be H)." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:24127
name: fungicide
def: "A substance used to destroy fungal pests." []
is_a: CHEBI:25944 ! pesticide
is_a: CHEBI:35718 ! antifungal agent

[Term]
id: CHEBI:24128
name: furanocoumarin
def: "Any furochromene that consists of a furan ring fused with a coumarin. The fusion may occur in different ways in give several isomers." []
is_a: CHEBI:39432 ! furochromene

[Term]
id: CHEBI:24129
name: furans
def: "Compounds containing at least one furan ring." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:24144
name: galactoglucomannan
def: "A heteroglycan that consists of a backbone of randomly distributed (1→4)-linked mannose and glucose units with (1→6)-linked galactose units attached to mannose units." []
is_a: CHEBI:61298 ! D-glucose- and/or D-galactose-substituted mannan

[Term]
id: CHEBI:24156
name: galactosamine
is_a: CHEBI:24586 ! hexosamine

[Term]
id: CHEBI:24221
name: 3,7-dimethylocta-2,6-dien-1-ol
is_a: CHEBI:134394 ! primary allylic alcohol
is_a: CHEBI:25409 ! monoterpenoid
is_a: CHEBI:25639 ! octadienol
is_a: CHEBI:26199 ! polyprenol

[Term]
id: CHEBI:24250
name: gibberellin
is_a: CHEBI:23849 ! diterpenoid
is_a: CHEBI:33575 ! carboxylic acid
relationship: RO:0000087 CHEBI:37848 ! has role plant hormone
relationship: RO:0018034 CHEBI:59139 ! is protonated form of gibberellin carboxylic acid anion
relationship: RO:0018040 CHEBI:36766 ! has parent hydride ent-gibberellane

[Term]
id: CHEBI:24261
name: glucocorticoid
def: "Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood." []
is_a: CHEBI:36699 ! corticosteroid hormone

[Term]
id: CHEBI:24268
name: glucooligosaccharide
def: "An oligosaccharide comprised of glucose residues." []
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:24271
name: glucosamines
def: "Any  hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group." []
is_a: CHEBI:24586 ! hexosamine

[Term]
id: CHEBI:24278
name: glucoside
is_a: CHEBI:35313 ! hexoside

[Term]
id: CHEBI:24279
name: glucosinolate
def: "Water-soluble anionic substituted thioglucosides. Glucosinolates have a central C atom which is bonded via an S atom to a glycone group and via an N atom to a sulfonated oxime group, and which also carries a side-group. The side-chain and sulfate group have an <i>anti</i> stereochemical configuration across the C=N double bond." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24401 ! glycosinolate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:79316 ! is deprotonated form of glucosinolic acid

[Term]
id: CHEBI:24289
name: glucosyl-N(6)-isopentenyladenine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38643 ! 6-isopentenylaminopurine
relationship: RO:0000087 CHEBI:23530 ! has role cytokinin

[Term]
id: CHEBI:24302
name: glucosiduronic acid
def: "Any substance produced by linking glucuronic acid to another substance via a glycosidic bond." []
is_a: CHEBI:35314 ! glycosiduronic acid
is_a: CHEBI:63436 ! carbohydrate acid derivative

[Term]
id: CHEBI:24315
name: glutamic acid derivative
def: "An amino acid derivative resulting from reaction of glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamic acid residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:18237 ! has functional parent glutamic acid

[Term]
id: CHEBI:24318
name: glutamine family amino acid
def: "An <small>L</small>-α-amino acid which is <small>L</small>-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class." []
is_a: CHEBI:15705 ! L-alpha-amino acid
is_a: CHEBI:83813 ! proteinogenic amino acid

[Term]
id: CHEBI:24319
name: EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
def: "An EC 6.3.* (<em>C</em>‒<em>N</em> bond-forming ligase) inhibitor that interferes with the action of glutamate—ammonia ligase (EC 6.3.1.2)." []
is_a: CHEBI:76823 ! EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor

[Term]
id: CHEBI:24329
name: glutarate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of glutaric acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:17859 ! is deprotonated form of glutaric acid

[Term]
id: CHEBI:24337
name: glutathione derivative
def: "Any organonitrogen compound derived from the Glu-Cys-Gly tripeptide glutathione." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0018038 CHEBI:16856 ! has functional parent glutathione

[Term]
id: CHEBI:24353
name: glycerol ether
def: "Any ether having glyceryl as at least one of the <em>O</em>-substituents." []
is_a: CHEBI:25698 ! ether
relationship: RO:0018038 CHEBI:17754 ! has functional parent glycerol

[Term]
id: CHEBI:24373
name: glycine derivative
def: "A proteinogenic amino acid derivative resulting from reaction of glycine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom." []
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:15428 ! has functional parent glycine

[Term]
id: CHEBI:24384
name: glycogens
is_a: CHEBI:37163 ! glucan

[Term]
id: CHEBI:24396
name: glycopeptide
def: "Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide." []
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:24400
name: glycoside
def: "A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO‒, RS‒, RSe‒, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms <em>N</em>-glycosides and <em>C</em>-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and <em>C</em>-glycosyl compounds, respectively." []
is_a: CHEBI:63161 ! glycosyl compound

[Term]
id: CHEBI:24401
name: glycosinolate
def: "An sulfur oxoanion resulting from the deprotonation of the hydroxy group attached to the sulfur of a glycosinolic acid." []
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: RO:0018033 CHEBI:79313 ! is deprotonated form of glycosinolic acid

[Term]
id: CHEBI:24402
name: glycosphingolipid
def: "A glycosphingolipid is a glycolipid that is a carbohydrate-containing derivative of a sphingoid or ceramide. It is understood that the carbohydrate residue is attached by a glycosidic linkage to O-1 of the sphingoid." []
is_a: CHEBI:26739 ! sphingolipid
is_a: CHEBI:33563 ! glycolipid

[Term]
id: CHEBI:24405
name: glycosylglucose
is_a: CHEBI:36233 ! disaccharide

[Term]
id: CHEBI:24407
name: glycosyl glycoside
def: "Any disaccharide in which the two monosaccharide components are connected by a glycosidic linkage between their anomeric centres." []
is_a: CHEBI:36233 ! disaccharide

[Term]
id: CHEBI:24431
name: chemical entity
def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." []

[Term]
id: CHEBI:24432
name: biological role
def: "A role played by the molecular entity or part thereof within a biological context." []
is_a: CHEBI:50906 ! role

[Term]
id: CHEBI:24433
name: group
def: "A defined linked collection of atoms or a single atom within a molecular entity." []
is_a: CHEBI:24431 ! chemical entity
relationship: BFO:0000051 CHEBI:33250 ! has part atom

[Term]
id: CHEBI:24436
name: guanidines
def: "Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R<small><sup>1</small></sup>R<small><sup>2</small></sup>N)(R<small><sup>3</small></sup>R<small><sup>4</small></sup>N)C=N-R<small><sup>5</small></sup> and are related structurally to amidines and ureas." []
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:24439
name: guanidinoacetic acids
is_a: CHEBI:21672 ! N-amidino-amino acid
is_a: CHEBI:24373 ! glycine derivative

[Term]
id: CHEBI:24455
name: guanosine phosphate
is_a: CHEBI:61295 ! guanyl ribonucleotide

[Term]
id: CHEBI:24458
name: guanosines
def: "Any purine ribonucleoside that is a derivative of guanosine." []
is_a: CHEBI:26399 ! purine ribonucleoside
relationship: RO:0018038 CHEBI:16235 ! has functional parent guanine

[Term]
id: CHEBI:24469
name: haloalkane
def: "A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom." []
is_a: CHEBI:24472 ! halohydrocarbon

[Term]
id: CHEBI:24470
name: haloamino acid
def: "Any non-proteinogenic amino acid carrying at least one halo group." []
is_a: CHEBI:83820 ! non-proteinogenic amino acid

[Term]
id: CHEBI:24471
name: halogen molecular entity
is_a: CHEBI:33675 ! p-block molecular entity
relationship: BFO:0000051 CHEBI:24473 ! has part halogen

[Term]
id: CHEBI:24472
name: halohydrocarbon
def: "A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom." []
is_a: CHEBI:17792 ! organohalogen compound
relationship: RO:0018040 CHEBI:24632 ! has parent hydride hydrocarbon

[Term]
id: CHEBI:24473
name: halogen
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:24505
name: heparins
is_a: CHEBI:35722 ! sulfated glycosaminoglycan
is_a: CHEBI:37395 ! mucopolysaccharide

[Term]
id: CHEBI:24527
name: herbicide
def: "A substance used to destroy plant pests." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:24531
name: heterocyclic antibiotic
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24532 ! organic heterocyclic compound
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:24532
name: organic heterocyclic compound
def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." []
is_a: CHEBI:33285 ! heteroorganic entity
is_a: CHEBI:33832 ! organic cyclic compound
is_a: CHEBI:5686 ! heterocyclic compound

[Term]
id: CHEBI:24533
name: heterodetic cyclic peptide
def: "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." []
is_a: CHEBI:23449 ! cyclic peptide

[Term]
id: CHEBI:24536
name: hexachlorocyclohexane
is_a: CHEBI:39154 ! chlorocyclohexane

[Term]
id: CHEBI:24548
name: hexadecenoic acid
def: "A C<small><sub>16</sub></small> straight-chain monounsaturated fatty acid having one C=C double bond." []
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:25413 ! monounsaturated fatty acid
is_a: CHEBI:53339 ! olefinic fatty acid
is_a: CHEBI:59202 ! straight-chain fatty acid
relationship: RO:0018034 CHEBI:78095 ! is protonated form of hexadecenoate

[Term]
id: CHEBI:24556
name: 1,3,5-trinitro-1,3,5-triazinane
def: "An <em>N</em>-nitro compound that is 1,3,5-triazinane in which all three of the hydrogens attached to the nitrogens have been replaced by nitro groups. It is widely used in both industrial and military explosives." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38779 ! 1,3,5-triazinanes
is_a: CHEBI:38780 ! N-nitro compound
relationship: RO:0000087 CHEBI:63490 ! has role explosive

[Term]
id: CHEBI:24561
name: hexahydroxyflavone
def: "Members of the class of hydroxyflavone that is  flavone substituted by 6 hydroxy groups." []
is_a: CHEBI:24698 ! hydroxyflavone

[Term]
id: CHEBI:24565
name: hexamethylphosphoric triamide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17102 ! phosphoramide
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:67105 ! has role insect sterilant

[Term]
id: CHEBI:24580
name: hexenoic acid
def: "A C<small><sub>6</sub></small>, medium-chain fatty acid carrying a double bond at any position along the main chain." []
is_a: CHEBI:25413 ! monounsaturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid

[Term]
id: CHEBI:24583
name: hexitol
is_a: CHEBI:17522 ! alditol

[Term]
id: CHEBI:24586
name: hexosamine
def: "Any 6-carbon amino monosaccharide with at least one alcoholic hydroxy group replaced by an amino group." []
is_a: CHEBI:60926 ! amino monosaccharide

[Term]
id: CHEBI:24610
name: homocysteines
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid

[Term]
id: CHEBI:24613
name: homodetic cyclic peptide
def: "A homodetic cyclic peptide is a cyclic peptide in which the ring consists solely of amino-acid residues in peptide linkages." []
is_a: CHEBI:23449 ! cyclic peptide

[Term]
id: CHEBI:24621
name: hormone
def: "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." []
is_a: CHEBI:33280 ! molecular messenger
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:24628
name: imidazolidine-2,4-dione
def: "An imidazolidinone with oxo groups at position 2 and 4." []
is_a: CHEBI:55370 ! imidazolidinone

[Term]
id: CHEBI:24631
name: hydrazines
def: "Hydrazine (diazane) and its substituted derivatives." []
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:24632
name: hydrocarbon
def: "A compound consisting of carbon and hydrogen only." []
is_a: CHEBI:33245 ! organic fundamental parent

[Term]
id: CHEBI:24644
name: HPETE
def: "Mono-hydroperoxy (e)icosatetraenoic acids (HPETEs) are the primary products of lipoxygenase-catalysed oxygenation of arachidonic acid." []
is_a: CHEBI:189832 ! hydroperoxy polyunsaturated fatty acid
is_a: CHEBI:23899 ! icosanoid
relationship: RO:0018034 CHEBI:59720 ! is protonated form of HPETE anion

[Term]
id: CHEBI:24646
name: hydroquinones
def: "Benzenediols that have the hydroxy substituents in the 1- and 4-positions." []
is_a: CHEBI:33570 ! benzenediols

[Term]
id: CHEBI:24648
name: hydroxamic acid anion
def: "An oxoanion resulting from the removal of a proton from the hydroxy group of any hydroxamic acid." []
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:35406 ! oxoanion
relationship: RO:0018033 CHEBI:24650 ! is deprotonated form of hydroxamic acid

[Term]
id: CHEBI:24650
name: hydroxamic acid
def: "A compound, R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>NHOH, derived from an oxoacid R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH) (<em>l</em> ≠ 0) by replacing ‒OH with ‒NHOH, and derivatives thereof. Specific examples of hydroxamic acids are preferably named as <em>N</em>-hydroxy amides." []
is_a: CHEBI:37622 ! carboxamide
relationship: RO:0018034 CHEBI:24648 ! is protonated form of hydroxamic acid anion

[Term]
id: CHEBI:24651
name: hydroxides
def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH<small><sup>−</small></sup>)." []
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:33608 ! hydrogen molecular entity
is_a: CHEBI:37577 ! heteroatomic molecular entity
relationship: BFO:0000051 CHEBI:43176 ! has part hydroxy group

[Term]
id: CHEBI:24654
name: hydroxy fatty acid
def: "Any fatty acid carrying one or more hydroxy substituents." []
is_a: CHEBI:35366 ! fatty acid
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid
relationship: RO:0018034 CHEBI:59835 ! is protonated form of hydroxy fatty acid anion

[Term]
id: CHEBI:24662
name: hydroxy-amino acid
def: "A non-proteinogenic α-amino acid bearing one or more hydroxy groups at unspecified positions." []
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid

[Term]
id: CHEBI:24663
name: hydroxy-5beta-cholanic acid
def: "Any member of the class of 5β-cholanic acids carrying at least one hydroxy group at unspecified position." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:36248 ! 5beta-cholanic acids
relationship: RO:0018038 CHEBI:36238 ! has functional parent 5beta-cholanic acid

[Term]
id: CHEBI:24669
name: hydroxy carboxylic acid
def: "Any carboxylic acid with at least one hydroxy group." []
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:24675
name: hydroxybenzoate
def: "Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent." []
is_a: CHEBI:22718 ! benzoates
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0018033 CHEBI:24676 ! is deprotonated form of hydroxybenzoic acid

[Term]
id: CHEBI:24676
name: hydroxybenzoic acid
def: "Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:33853 ! phenols
relationship: RO:0018034 CHEBI:24675 ! is protonated form of hydroxybenzoate
relationship: RO:0018038 CHEBI:30746 ! has functional parent benzoic acid

[Term]
id: CHEBI:24677
name: hydroxybenzophenone
def: "Any benzophenone into which is substituted one or more hydroxy groups." []
is_a: CHEBI:22726 ! benzophenones
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:24679
name: hydroxybenzyl alcohol
def: "Any member of the class of benzyl alcohols that is a benzyl alcohol substituted by at least one hydroxy group on the benzene ring." []
is_a: CHEBI:22743 ! benzyl alcohols
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:2468
name: secondary alpha-hydroxy ketone
def: "An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing one hydrogen and one organyl group. Secondary α-hydroxy ketones are also known as acyloins, and are formally derived from reductive coupling of two carboxylic acid groups." []
is_a: CHEBI:139588 ! alpha-hydroxy ketone
is_a: CHEBI:35681 ! secondary alcohol

[Term]
id: CHEBI:24681
name: hydroxybiphenyls
def: "Any member of the class of biphenyls that has one or more hydroxy groups attached to the benzenoid ring system." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:24688
name: monohydroxycinnamic acid
is_a: CHEBI:24689 ! hydroxycinnamic acid

[Term]
id: CHEBI:24689
name: hydroxycinnamic acid
def: "Any member of the class of  cinnamic acids carrying one or more hydroxy substituents." []
is_a: CHEBI:23252 ! cinnamic acids

[Term]
id: CHEBI:24697
name: hydroxyflavanone
def: "A member of the class of flavanones that consists of flavanone with one or more hydroxy substituents." []
is_a: CHEBI:28863 ! flavanones
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:24698
name: hydroxyflavone
def: "Any flavone in which one or more ring hydrogens are replaced by hydroxy groups." []
is_a: CHEBI:24043 ! flavones
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:24709
name: hydroxylamines
def: "Hydroxylamine, H<small><sub>2</sub></small>N‒OH, and its hydrocarbyl derivatives." []
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:24712
name: hydroxymethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group
relationship: RO:0018037 CHEBI:17790 ! is substitutent group from methanol

[Term]
id: CHEBI:24727
name: hydroxynaphthalene
def: "Any member of the class of  naphthalenes that is naphthalene carrying one or more hydroxy groups." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:24730
name: hydroxynitrile
def: "Any nitrile compound which also contains a hydroxy group." []
is_a: CHEBI:18379 ! nitrile

[Term]
id: CHEBI:24734
name: hydroxyphenylalanine
is_a: CHEBI:24662 ! hydroxy-amino acid
is_a: CHEBI:25985 ! phenylalanine derivative
is_a: CHEBI:33856 ! aromatic amino acid

[Term]
id: CHEBI:24745
name: hydroxypyridine
def: "Any member of the class of pyridines with at least one hydroxy substituent." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:74818 ! heteroaryl hydroxy compound

[Term]
id: CHEBI:24751
name: hydroxytoluene
def: "Any member of the class of  toluenes carrying one or more hydroxy substituents." []
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:24757
name: hypochlorous acid
def: "A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water." []
is_a: CHEBI:26523 ! reactive oxygen species
is_a: CHEBI:33426 ! chlorine oxoacid
is_a: CHEBI:35406 ! oxoanion
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:76797 ! has role EC 2.5.1.18 (glutathione transferase) inhibitor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:29222 ! is protonated form of hypochlorite

[Term]
id: CHEBI:24780
name: imidazoles
def: "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." []
is_a: CHEBI:23677 ! diazole

[Term]
id: CHEBI:24782
name: imide
is_a: CHEBI:33257 ! secondary amide

[Term]
id: CHEBI:24783
name: imine
def: "Compounds having the structure RN=CR<small><sub>2</sub></small> (R = H, hydrocarbyl). Thus analogues of aldehydes or ketones, having NR doubly bonded to carbon; aldimines have the structure RCH=NR, ketimines have the structure R'<small><sub>2</sub></small>C=NR (where R' is not H). Imines include azomethines and Schiff bases. Imine is used as a suffix in systematic nomenclature to denote the C=NH group excluding the carbon atom." []
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:24789
name: indanones
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:46940 ! indanes

[Term]
id: CHEBI:24803
name: indole-3-acetic acids
def: "An  indol-3-yl carboxylic acid in which the carboxylic acid specified is acetic acid." []
is_a: CHEBI:24810 ! indol-3-yl carboxylic acid
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:24809
name: indole-3-carboxylic acid
def: "An indole-3-carboxylic acid carrying a carboxy group at position 3." []
is_a: CHEBI:24810 ! indol-3-yl carboxylic acid
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:62448 ! is protonated form of indole-3-carboxylate

[Term]
id: CHEBI:24810
name: indol-3-yl carboxylic acid
def: "Any indolyl carboxylic acid carrying an indol-3-yl or substituted indol-3-yl group." []
is_a: CHEBI:46867 ! indolyl carboxylic acid

[Term]
id: CHEBI:24814
name: indole-3-methanol
def: "An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38467 ! indolyl alcohol
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:24828
name: indoles
def: "Any compound containing an indole skeleton." []
is_a: CHEBI:22728 ! benzopyrrole

[Term]
id: CHEBI:24829
name: indolones
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:24833
name: oxoacid
def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24651 ! hydroxides
relationship: RO:0000087 CHEBI:39141 ! has role Bronsted acid

[Term]
id: CHEBI:24834
name: inorganic anion
is_a: CHEBI:22563 ! anion
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:24835
name: inorganic molecular entity
def: "A molecular entity that contains no carbon." []
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:24836
name: inorganic oxide
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:25741 ! oxide

[Term]
id: CHEBI:24837
name: inorganic peroxide
def: "Compounds of structure ROOR' in which R and R' are inorganic groups." []
is_a: CHEBI:24836 ! inorganic oxide
is_a: CHEBI:25940 ! peroxides

[Term]
id: CHEBI:24838
name: inorganic phosphate
def: "Any  phosphate that contains no carbon atom." []
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:26020 ! phosphate

[Term]
id: CHEBI:24839
name: inorganic salt
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:24866 ! salt

[Term]
id: CHEBI:24840
name: inorganic sulfate salt
is_a: CHEBI:24839 ! inorganic salt
is_a: CHEBI:35175 ! sulfate salt

[Term]
id: CHEBI:24843
name: inosine phosphate
is_a: CHEBI:25608 ! nucleoside phosphate

[Term]
id: CHEBI:24844
name: inosines
def: "Any purine ribonucleoside that is a derivative of inosine." []
is_a: CHEBI:26399 ! purine ribonucleoside

[Term]
id: CHEBI:24848
name: inositol
def: "Any cyclohexane-1,2,3,4,5,6-hexol." []
is_a: CHEBI:23451 ! cyclitol
is_a: CHEBI:37206 ! hexol

[Term]
id: CHEBI:24850
name: insect attractant
def: "A chemical that attracts insects." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:24851
name: insect growth regulator
def: "A growth regulator that inhibits the life cycle of an insect." []
is_a: CHEBI:24852 ! insecticide
is_a: CHEBI:39317 ! growth regulator

[Term]
id: CHEBI:24852
name: insecticide
def: "Strictly, a substance intended to kill members of the class <em>Insecta</em>.  In common usage, any substance used for preventing, destroying, repelling or controlling insects." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:24853
name: intercalator
def: "A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages." []
is_a: CHEBI:25435 ! mutagen

[Term]
id: CHEBI:24858
name: iodide salt
is_a: CHEBI:24860 ! iodine molecular entity
is_a: CHEBI:33958 ! halide salt
relationship: BFO:0000051 CHEBI:16382 ! has part iodide

[Term]
id: CHEBI:24859
name: iodine atom
def: "Chemical element with atomic number 53." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24473 ! halogen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:24860
name: iodine molecular entity
is_a: CHEBI:24471 ! halogen molecular entity
relationship: BFO:0000051 CHEBI:24859 ! has part iodine atom

[Term]
id: CHEBI:24862
name: iodoamino acid
def: "An amino acid containing at least one iodo substituent." []
is_a: CHEBI:24470 ! haloamino acid
is_a: CHEBI:37142 ! organoiodine compound

[Term]
id: CHEBI:24863
name: iodophenol
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:38856 ! halophenol

[Term]
id: CHEBI:24864
name: iodothyronine
def: "An  iodoamino acid in which the amino acid specified is  thyronine." []
is_a: CHEBI:24862 ! iodoamino acid
is_a: CHEBI:33853 ! phenols
relationship: RO:0018034 CHEBI:63477 ! is protonated form of iodothyroninate
relationship: RO:0018038 CHEBI:30661 ! has functional parent thyronine

[Term]
id: CHEBI:24866
name: salt
def: "A salt is an assembly of cations and anions." []
is_a: CHEBI:37577 ! heteroatomic molecular entity
relationship: BFO:0000051 CHEBI:22563 ! has part anion
relationship: BFO:0000051 CHEBI:36916 ! has part cation

[Term]
id: CHEBI:24867
name: monoatomic ion
is_a: CHEBI:24870 ! ion
is_a: CHEBI:33238 ! monoatomic entity

[Term]
id: CHEBI:24868
name: organic salt
is_a: CHEBI:24866 ! salt

[Term]
id: CHEBI:24869
name: ionophore
def: "A compound which can carry specific ions through membranes of cells or organelles." []
is_a: CHEBI:38632 ! membrane transport modulator

[Term]
id: CHEBI:24870
name: ion
def: "A molecular entity having a net electric charge." []
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:24873
name: iron molecular entity
is_a: CHEBI:33744 ! iron group molecular entity
relationship: BFO:0000051 CHEBI:18248 ! has part iron atom

[Term]
id: CHEBI:24874
name: iron ionophore
def: "Any  ionophore capable of transportation of iron ions across membranes." []
is_a: CHEBI:24869 ! ionophore

[Term]
id: CHEBI:24875
name: iron cation
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:82663 ! elemental iron
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:24897
name: isoindoles
is_a: CHEBI:22728 ! benzopyrrole

[Term]
id: CHEBI:24898
name: isoleucine
def: "A 2-amino-3-methylpentanoic acid having either (2<i>R</i>,3<i>R</i>)- or (2<i>S</i>,3<i>S</i>)-configuration." []
is_a: CHEBI:38264 ! 2-amino-3-methylpentanoic acid
relationship: BFO:0000051 CHEBI:45557 ! has part sec-butyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32613 ! is deprotonated form of isoleucinium
relationship: RO:0018034 CHEBI:32612 ! is protonated form of isoleucinate

[Term]
id: CHEBI:24913
name: isoprenoid
def: "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." []
is_a: CHEBI:18059 ! lipid

[Term]
id: CHEBI:24921
name: isoquinoline alkaloid
def: "Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine." []
is_a: CHEBI:22315 ! alkaloid

[Term]
id: CHEBI:24922
name: isoquinolines
def: "A class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives." []
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:24928
name: isothiocyanic acid
is_a: CHEBI:33405 ! hydracid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018034 CHEBI:18022 ! is protonated form of thiocyanate
relationship: RO:0018036 CHEBI:29200 ! is tautomer of thiocyanic acid

[Term]
id: CHEBI:24937
name: jasmonates
def: "The jasmonates (JAs) are a group of plant hormones which help regulate plant growth and development." []
is_a: CHEBI:37848 ! plant hormone

[Term]
id: CHEBI:24941
name: juvenile hormone antagonists
is_a: CHEBI:24851 ! insect growth regulator

[Term]
id: CHEBI:24942
name: juvenile hormone mimic
is_a: CHEBI:24851 ! insect growth regulator

[Term]
id: CHEBI:24951
name: kanamycins
is_a: CHEBI:22479 ! amino cyclitol glycoside
is_a: CHEBI:22507 ! aminoglycoside antibiotic

[Term]
id: CHEBI:24960
name: ketoaldehyde
def: "Any compound that has an aldehydic and ketonic group in the same molecule." []
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:24961
name: ketoaldonate
is_a: CHEBI:33721 ! carbohydrate acid anion

[Term]
id: CHEBI:24963
name: ketoaldonic acid
def: "Oxo carboxylic acids formally derived from aldonic acids by replacement of a secondary CHOH group by a carbonyl group." []
is_a: CHEBI:33720 ! carbohydrate acid
is_a: CHEBI:35381 ! monosaccharide

[Term]
id: CHEBI:24973
name: ketohexose
def: "Any hexose containing a single ketone group." []
is_a: CHEBI:18133 ! hexose
is_a: CHEBI:24978 ! ketose

[Term]
id: CHEBI:24978
name: ketose
def: "Ketonic parent sugars (polyhydroxy ketones H[CH(OH)]<small><sub>n</sub></small>C(=O)[CH(OH)]<em><small><sub>m</sub></small></em>H) and their intramolecular hemiketals." []
is_a: CHEBI:35381 ! monosaccharide

[Term]
id: CHEBI:24995
name: lactam
def: "Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." []
is_a: CHEBI:23443 ! cyclic amide
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:24996
name: lactate
def: "A hydroxy monocarboxylic acid anion that is the conjugate base of lactic acid, arising from deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28358 ! is deprotonated form of rac-lactic acid
relationship: RO:0018033 CHEBI:78320 ! is deprotonated form of 2-hydroxypropanoic acid
relationship: RO:0018038 CHEBI:17272 ! has functional parent propionate

[Term]
id: CHEBI:25000
name: lactone
def: "Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:25016
name: lead atom
is_a: CHEBI:233500 ! post-transition metal atom
is_a: CHEBI:33306 ! carbon group element atom

[Term]
id: CHEBI:25017
name: leucine
def: "A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the α-carbon is substituted by an isobutyl group." []
is_a: CHEBI:22918 ! branched-chain amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:30356 ! has part isobutyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32628 ! is deprotonated form of leucinium
relationship: RO:0018034 CHEBI:32627 ! is protonated form of leucinate

[Term]
id: CHEBI:25022
name: leucomycin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25106 ! macrolide
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:25036
name: lignan
def: "Any phenylpropanoid  derived from phenylalanine via dimerization of substituted cinnamic alcohols, known as monolignols, to a dibenzylbutane skeleton. Note that while individual members of the class have names ending ...lignane, ...lignene, ...lignadiene, etc., the class names lignan, neolignan, etc., do not end with an \"e\"." []
is_a: CHEBI:26004 ! phenylpropanoid

[Term]
id: CHEBI:2504
name: aflatoxin B1
def: "An aflatoxin having a tetrahydrocyclopenta[<em>c</em>]furo[3',2':4,5]furo[2,3-<em>h</em>]chromene skeleton with oxygen functionality at positions 1, 4 and 11." []
is_a: CHEBI:22271 ! aflatoxin
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:25046
name: linear tetrapyrrole
is_a: CHEBI:26932 ! tetrapyrrole

[Term]
id: CHEBI:25048
name: linolenic acid
def: "A two-membered subclass of octadecatrienoic acid comprising the (9<i>Z</i>,12<i>Z</i>,15<i>Z</i>)- and (6<i>Z</i>,9<i>Z</i>,12<i>Z</i>)-isomers. Linolenic acids are nutrients essential to the formation of prostaglandins and are also used in making paints and synthetic resins." []
is_a: CHEBI:25633 ! octadecatrienoic acid
is_a: CHEBI:59549 ! essential fatty acid
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:133790 ! is protonated form of linolenate

[Term]
id: CHEBI:25061
name: lipopeptide antibiotic
is_a: CHEBI:25903 ! peptide antibiotic
is_a: CHEBI:46895 ! lipopeptide

[Term]
id: CHEBI:25094
name: lysine
def: "A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6." []
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:35987 ! diamino acid
relationship: BFO:0000051 CHEBI:50339 ! has part 4-aminobutyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32564 ! is deprotonated form of lysinium(1+)
relationship: RO:0018034 CHEBI:32563 ! is protonated form of lysinate
relationship: RO:0018038 CHEBI:30776 ! has functional parent hexanoic acid

[Term]
id: CHEBI:25105
name: macrolide antibiotic
def: "A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25106 ! macrolide
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:25106
name: macrolide
def: "A macrocyclic lactone with a ring of twelve or more members derived from a polyketide." []
is_a: CHEBI:26188 ! polyketide
is_a: CHEBI:63944 ! macrocyclic lactone

[Term]
id: CHEBI:25107
name: magnesium atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22313 ! alkaline earth metal atom
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:25108
name: magnesium molecular entity
is_a: CHEBI:33299 ! alkaline earth molecular entity
relationship: BFO:0000051 CHEBI:25107 ! has part magnesium atom

[Term]
id: CHEBI:25115
name: malate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of malic acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
relationship: RO:0018033 CHEBI:6650 ! is deprotonated form of malic acid

[Term]
id: CHEBI:25140
name: maltodextrin
def: "A dextrin in which the <small>D</small>-glucose units are linked by α-(1→4) glycosidic bonds." []
is_a: CHEBI:28675 ! dextrin
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:25154
name: manganese molecular entity
is_a: CHEBI:33743 ! manganese group molecular entity
relationship: BFO:0000051 CHEBI:18291 ! has part manganese atom

[Term]
id: CHEBI:25155
name: manganese cation
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:35115 ! elemental manganese

[Term]
id: CHEBI:25185
name: menaquinones
def: "Any prenylnaphthoquinone having a prenyl or polyprenyl group at position 3 and a methyl group at position 2 on the naphthoquinone ring." []
is_a: CHEBI:26254 ! prenylnaphthoquinone

[Term]
id: CHEBI:25189
name: 1,4-dimercaptobutane-2,3-diol
def: "A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group." []
is_a: CHEBI:13643 ! glycol
is_a: CHEBI:22944 ! butanediols
is_a: CHEBI:29256 ! thiol

[Term]
id: CHEBI:25195
name: mercury atom
is_a: CHEBI:33340 ! zinc group element atom

[Term]
id: CHEBI:25196
name: mercury molecular entity
is_a: CHEBI:33673 ! zinc group molecular entity
relationship: BFO:0000051 CHEBI:25195 ! has part mercury atom

[Term]
id: CHEBI:25197
name: mercury cation
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:35113 ! elemental mercury

[Term]
id: CHEBI:25212
name: metabolite
def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:25213
name: metal cation
is_a: CHEBI:23906 ! monoatomic cation
is_a: CHEBI:36915 ! inorganic cation

[Term]
id: CHEBI:25218
name: methacrylate
def: "A monocarboxylic acid anion that is obtained by removal of a proton from the carboxylic acid group of methacrylic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:25219 ! is deprotonated form of methacrylic acid
relationship: RO:0018038 CHEBI:37080 ! has functional parent acrylate

[Term]
id: CHEBI:25219
name: methacrylic acid
def: "An α,β-unsaturated monocarboxylic acid that is acrylic acid in which the hydrogen at position 2 is substituted by a methyl group." []
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
relationship: RO:0018034 CHEBI:25218 ! is protonated form of methacrylate
relationship: RO:0018038 CHEBI:18308 ! has functional parent acrylic acid

[Term]
id: CHEBI:25222
name: methanediols
def: "A  diol that is methane in which two of the hydrogens have been replaced by hydroxy groups respectively." []
is_a: CHEBI:23824 ! diol

[Term]
id: CHEBI:25223
name: methanesulfonate ester
def: "An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol." []
is_a: CHEBI:48544 ! methanesulfonates
is_a: CHEBI:83347 ! organosulfonic ester

[Term]
id: CHEBI:25224
name: methanesulfonate
def: "A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid." []
is_a: CHEBI:62081 ! 1,1-diunsubstituted alkanesulfonate
relationship: RO:0018033 CHEBI:27376 ! is deprotonated form of methanesulfonic acid

[Term]
id: CHEBI:25235
name: monomethoxybenzene
def: "Compounds containing a benzene skeleton substituted with one methoxy group." []
is_a: CHEBI:51683 ! methoxybenzenes

[Term]
id: CHEBI:25236
name: methoxybenzoate
is_a: CHEBI:22718 ! benzoates

[Term]
id: CHEBI:25238
name: methoxybenzoic acid
def: "Any benzoic acid carrying one or more methoxy substituents." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:51683 ! methoxybenzenes

[Term]
id: CHEBI:25240
name: methoxyflavanone
def: "A member of the class of flavanones that consists of flavanone with one or more methoxy substituents." []
is_a: CHEBI:28863 ! flavanones
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:25241
name: methoxyflavone
def: "Any member of the class of flavones with at least one methoxy substituent." []
is_a: CHEBI:24043 ! flavones
is_a: CHEBI:25698 ! ether

[Term]
id: CHEBI:25248
name: methyl ester
def: "Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:17790 ! has functional parent methanol

[Term]
id: CHEBI:25253
name: methyl halides
def: "A haloalkane that is methane in which one of the hydrogens is substituted by a halide atom." []
is_a: CHEBI:39279 ! halomethane

[Term]
id: CHEBI:25255
name: methyl methanesulfonate
def: "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25223 ! methanesulfonate ester
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:25272
name: methyladenine
def: "Any member of the class of 6-aminopurines that is adenine bearing a single methyl substituent." []
is_a: CHEBI:20706 ! 6-aminopurines
relationship: RO:0018038 CHEBI:16708 ! has functional parent adenine

[Term]
id: CHEBI:25274
name: methylamines
is_a: CHEBI:22331 ! alkylamines

[Term]
id: CHEBI:25275
name: methylaniline
def: "A substituted aniline carrying one or more methyl groups at unspecified positions." []
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:25280
name: methylbenzoic acid
is_a: CHEBI:22723 ! benzoic acids

[Term]
id: CHEBI:25322
name: methylmercury compound
def: "An  alkylmercury compound in which the  alkyl group specified is methyl." []
is_a: CHEBI:33255 ! alkylmercury compound

[Term]
id: CHEBI:2533
name: alachlor
def: "An aromatic amide that is <em>N</em>-(2,6-diethylphenyl)acetamide substituted by a methoxymethyl group at at the nitrogen atom while one of the hydrogens of the methyl group has been replaced by a chlorine atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:28884 ! has functional parent N-phenylacetamide

[Term]
id: CHEBI:25340
name: methylpyridines
def: "Any member of the class of pyridines that carries at least one methyl substituent." []
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:25345
name: methyltetrahydrofolate
def: "A group of heterocyclic compounds based on the <em>N</em>-methylated 5,6,7,8-tetrahydropteroic acid skeleton conjugated with one or more <small>L</small>-glutamic acid or <small>L</small>-glutamate units." []
is_a: CHEBI:67016 ! tetrahydrofolate

[Term]
id: CHEBI:25348
name: methylxanthine
is_a: CHEBI:26385 ! purine alkaloid
relationship: RO:0018038 CHEBI:15318 ! has functional parent xanthine

[Term]
id: CHEBI:25350
name: mevalonate
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-mevalonate." []
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:18790 ! has part (S)-mevalonate
relationship: BFO:0000051 CHEBI:36464 ! has part (R)-mevalonate
relationship: RO:0018033 CHEBI:25351 ! is deprotonated form of mevalonic acid

[Term]
id: CHEBI:25351
name: mevalonic acid
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-mevalonic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:17710 ! has part (R)-mevalonic acid
relationship: BFO:0000051 CHEBI:28880 ! has part (S)-mevalonic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018034 CHEBI:25350 ! is protonated form of mevalonate

[Term]
id: CHEBI:25354
name: mineralocorticoid
def: "Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism." []
is_a: CHEBI:36699 ! corticosteroid hormone

[Term]
id: CHEBI:25355
name: mitochondrial respiratory-chain inhibitor
is_a: CHEBI:38497 ! respiratory-chain inhibitor

[Term]
id: CHEBI:25357
name: mitomycin
def: "A family of aziridine-containing natural products isolated from <em>Streptomyces caespitosus</em> or <em>Streptomyces lavendulae</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:25830 ! p-quinones
is_a: CHEBI:38303 ! azirinopyrroloindole
relationship: RO:0000087 CHEBI:24853 ! has role intercalator
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:25362
name: elemental molecule
def: "A molecule all atoms of which have the same atomic number." []
is_a: CHEBI:25367 ! molecule
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:25367
name: molecule
def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." []
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:25370
name: molybdenum molecular entity
is_a: CHEBI:33741 ! chromium group molecular entity
relationship: BFO:0000051 CHEBI:28685 ! has part molybdenum atom

[Term]
id: CHEBI:25375
name: monoamine molecular messenger
def: "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group  (‒CH<small><sub>2</sub></small>‒CH<small><sub>2</sub></small>‒). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." []
is_a: CHEBI:63534 ! monoamine
relationship: RO:0000087 CHEBI:33280 ! has role molecular messenger

[Term]
id: CHEBI:25381
name: monoalkyl phosphate
is_a: CHEBI:22324 ! alkyl phosphate

[Term]
id: CHEBI:25384
name: monocarboxylic acid
def: "An oxoacid containing a single carboxy group." []
is_a: CHEBI:33575 ! carboxylic acid
relationship: RO:0018034 CHEBI:35757 ! is protonated form of monocarboxylic acid anion

[Term]
id: CHEBI:25388
name: monohydroxybenzoate
def: "A hydroxybenzoate carrying a single hydroxy substituent at unspecified position." []
is_a: CHEBI:24675 ! hydroxybenzoate
relationship: RO:0018033 CHEBI:25389 ! is deprotonated form of monohydroxybenzoic acid

[Term]
id: CHEBI:25389
name: monohydroxybenzoic acid
def: "Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring." []
is_a: CHEBI:24676 ! hydroxybenzoic acid
relationship: RO:0018034 CHEBI:25388 ! is protonated form of monohydroxybenzoate

[Term]
id: CHEBI:25392
name: naphthols
def: "Any hydroxynaphthalene derivative that has a single hydroxy substituent." []
is_a: CHEBI:24727 ! hydroxynaphthalene

[Term]
id: CHEBI:25399
name: cresol
def: "A hydroxytoluene that consists of toluene carrying a single hydroxy substituent at any position. A 'closed class'." []
is_a: CHEBI:24751 ! hydroxytoluene
is_a: CHEBI:87034 ! aromatic fungicide

[Term]
id: CHEBI:25401
name: monomethoxyflavone
def: "Any methoxyflavone with a single methoxy substituent." []
is_a: CHEBI:25241 ! methoxyflavone

[Term]
id: CHEBI:25408
name: monoterpene ketone
def: "A terpene ketone derived from a monoterpene." []
is_a: CHEBI:26872 ! terpene ketone

[Term]
id: CHEBI:25409
name: monoterpenoid
def: "Any terpenoid derived from a monoterpene. The term includes compounds in which the C<small><sub>10</sub></small> skeleton of the parent monoterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." []
is_a: CHEBI:26873 ! terpenoid
relationship: RO:0018040 CHEBI:35187 ! has parent hydride monoterpene

[Term]
id: CHEBI:25413
name: monounsaturated fatty acid
def: "Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment." []
is_a: CHEBI:27208 ! unsaturated fatty acid
relationship: RO:0018034 CHEBI:82680 ! is protonated form of monounsaturated fatty acid anion

[Term]
id: CHEBI:25414
name: monoatomic monocation
is_a: CHEBI:23906 ! monoatomic cation

[Term]
id: CHEBI:25418
name: morphinane alkaloid
def: "An  isoquinoline alkaloid based on a morphinan skeleton and its substituted derivatives." []
is_a: CHEBI:24921 ! isoquinoline alkaloid

[Term]
id: CHEBI:25430
name: monoatomic polycation
is_a: CHEBI:23906 ! monoatomic cation

[Term]
id: CHEBI:25434
name: bis(2-chloroethyl) sulfide
def: "An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23996 ! ethyl sulfide
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78592 ! has role vesicant

[Term]
id: CHEBI:25435
name: mutagen
def: "An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution." []
is_a: CHEBI:50902 ! genotoxin

[Term]
id: CHEBI:25442
name: mycotoxin
def: "Poisonous substance produced by fungi." []
is_a: CHEBI:27026 ! toxin
is_a: CHEBI:76946 ! fungal metabolite

[Term]
id: CHEBI:254496
name: 7,12-dimethyltetraphene
def: "A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke." []
synonym: "7,12-dimethylbenzo[a]anthracene" EXACT [ChEBI]
is_a: CHEBI:35296 ! ortho-fused polycyclic arene
is_a: CHEBI:51067 ! tetraphenes

[Term]
id: CHEBI:25477
name: naphthalenes
def: "Any benzenoid aromatic compound having a skeleton composed of two <em>ortho</em>-fused benzene rings." []
is_a: CHEBI:33836 ! benzenoid aromatic compound
is_a: CHEBI:36785 ! carbobicyclic compound

[Term]
id: CHEBI:25481
name: naphthoquinone
def: "A polycyclic aromatic ketone metabolite of naphthalene." []
is_a: CHEBI:36141 ! quinone

[Term]
id: CHEBI:2549
name: albuterol
def: "A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a <em>tert</em>-butyl group attached to the nirogen atom. It acts as a β-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD)." []
is_a: CHEBI:25990 ! phenylethanolamines
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:90753 ! has role antidote to organophosphate poisoning

[Term]
id: CHEBI:25491
name: nematicide
def: "A substance used to destroy pests of the phylum <em>Nematoda</em> (roundworms)." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:25495
name: neohesperidoside
def: "A glycoside containing α-<small>L</small>-rhamnopyranosyl-(1→2)-β-<small>D</small>-glucopyranosyl residue as the sugar unit." []
is_a: CHEBI:24400 ! glycoside
is_a: CHEBI:63353 ! disaccharide derivative
relationship: RO:0018038 CHEBI:73992 ! has functional parent alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranose

[Term]
id: CHEBI:25512
name: neurotransmitter
def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." []
is_a: CHEBI:33280 ! molecular messenger

[Term]
id: CHEBI:25513
name: neutral glycosphingolipid
def: "Any glycosphingolipid containing unsubstituted glycosyl moieties." []
is_a: CHEBI:24402 ! glycosphingolipid

[Term]
id: CHEBI:25516
name: nickel cation
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:60248 ! nickel ion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:25529
name: pyridinecarboxamide
def: "A member of the class of pyridines that is a substituted pyridine in which at least one of the substituents is a carboxamide or <em>N</em>-substituted caraboxamide group." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:25540
name: neonicotinoid insectide
def: "A class of neuro-active insecticides that act at the nicotinic acetylcholine receptor." []
is_a: CHEBI:24852 ! insecticide
is_a: CHEBI:47958 ! nicotinic acetylcholine receptor agonist
is_a: CHEBI:50910 ! neurotoxin

[Term]
id: CHEBI:25543
name: nitramine
def: "Amines substituted at N with a nitro group (a contracted form of <em>N</em>-nitroamines); they are thus amides of nitric acid, and the class is composed of nitramide, O<small><sub>2</sub></small>NNH<small><sub>2</sub></small>, and its derivatives formed by substitution." []
is_a: CHEBI:38780 ! N-nitro compound

[Term]
id: CHEBI:25548
name: nitrilotriacetate(3-)
def: "A tricarboxylic acid trianion resulting from the deprotonation of all three hydroxy groups of nitrilotriacetic acid." []
is_a: CHEBI:27092 ! tricarboxylic acid trianion
is_a: CHEBI:39054 ! NTA
relationship: RO:0018033 CHEBI:39056 ! is deprotonated form of nitrilotriacetate(2-)

[Term]
id: CHEBI:25549
name: nitrites
def: "Salts and esters of nitrous acid, HONO." []
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: RO:0018038 CHEBI:25567 ! has functional parent nitrous acid

[Term]
id: CHEBI:2555
name: aldicarb
def: "The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of <i>E</i> and <i>Z</i> isomers; it is not known which isomer is more active." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:38461 ! has role carbamate insecticide
relationship: RO:0018038 CHEBI:59059 ! has functional parent methyl isocyanate
relationship: RO:0018038 CHEBI:60330 ! has functional parent 2-methyl-2-(methylsulfanyl)propanal oxime

[Term]
id: CHEBI:25550
name: nitroaniline
def: "A substituted aniline that carries one or more nitro groups." []
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:25555
name: nitrogen atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33300 ! pnictogen
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient

[Term]
id: CHEBI:25558
name: organonitrogen heterocyclic antibiotic
is_a: CHEBI:24531 ! heterocyclic antibiotic
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:25560
name: nitroglycerol
def: "A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups." []
is_a: CHEBI:51080 ! nitrate ester
relationship: RO:0018038 CHEBI:17754 ! has functional parent glycerol

[Term]
id: CHEBI:25562
name: nitrophenol
def: "Any member of the class of  phenols or substituted phenols carrying  at least 1 nitro group." []
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35716 ! C-nitro compound

[Term]
id: CHEBI:25566
name: nitrotoluene
def: "Any member of the class of  toluenes bearing one or more nitro substituents on the benzene ring." []
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:35716 ! C-nitro compound

[Term]
id: CHEBI:25567
name: nitrous acid
is_a: CHEBI:33455 ! nitrogen oxoacid
relationship: RO:0018034 CHEBI:16301 ! is protonated form of nitrite

[Term]
id: CHEBI:25585
name: nonmetal atom
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:25605
name: nucleoside antibiotic
is_a: CHEBI:33281 ! antimicrobial agent

[Term]
id: CHEBI:25608
name: nucleoside phosphate
def: "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates." []
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:37734 ! phosphoric ester
is_a: CHEBI:61120 ! nucleobase-containing molecular entity
relationship: RO:0018038 CHEBI:33838 ! has functional parent nucleoside

[Term]
id: CHEBI:25626
name: octadecadienoate
def: "A long-chain, unsaturated fatty acid anion formed by deprotonation of the carboxy group of any octadecadienoic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131860 ! octadecanoid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:25627 ! is deprotonated form of octadecadienoic acid

[Term]
id: CHEBI:25627
name: octadecadienoic acid
def: "Any straight-chain, C<small><sub>18</sub></small> polyunsaturated fatty acid having two C=C double bonds." []
is_a: CHEBI:140949 ! fatty acid 18:2
is_a: CHEBI:26208 ! polyunsaturated fatty acid
is_a: CHEBI:36326 ! octadecanoid
is_a: CHEBI:53339 ! olefinic fatty acid
is_a: CHEBI:59202 ! straight-chain fatty acid
relationship: RO:0018034 CHEBI:25626 ! is protonated form of octadecadienoate

[Term]
id: CHEBI:25629
name: octadecanoate
def: "A fatty acid anion 18:0 that is the conjugate base of octadecanoic acid (stearic acid). Stearates have a variety of uses in the pharmaceutical industry." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:78125 ! fatty acid anion 18:0
is_a: CHEBI:83955 ! 2-saturated fatty acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28842 ! is deprotonated form of octadecanoic acid

[Term]
id: CHEBI:25633
name: octadecatrienoic acid
def: "Any trienoic fatty acid having eighteen carbons." []
is_a: CHEBI:132502 ! fatty acid 18:3
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:59202 ! straight-chain fatty acid
relationship: RO:0018034 CHEBI:36434 ! is protonated form of octadecatrienoate

[Term]
id: CHEBI:25634
name: octadecenoic acid
def: "Any member of the group of C<small><sub>18</sub></small> monounsaturated fatty acids with the double bond located at any position in the chain." []
is_a: CHEBI:140948 ! fatty acid 18:1
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:25413 ! monounsaturated fatty acid
is_a: CHEBI:53339 ! olefinic fatty acid
relationship: RO:0018034 CHEBI:78049 ! is protonated form of octadecenoate

[Term]
id: CHEBI:25639
name: octadienol
def: "A primary alcohol that is octanol consisting of two double bonds at unspecified positions." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:50582 ! alkenyl alcohol

[Term]
id: CHEBI:2564
name: aldrin
def: "An organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with norbornadiene. A proinsecticide (by epoxidation of the non-chlorinated double bond to give dieldrin), it was widely used as an insecticide before being banned in the 1970s as a persistent organic pollutant." []
is_a: CHEBI:25705 ! organochlorine insecticide
relationship: RO:0000087 CHEBI:136644 ! has role proinsecticide
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:25646
name: octanoate
def: "A straight-chain saturated fatty acid anion that is the conjugate base of octanoic acid (caprylic acid); believed to block adipogenesis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:78117 ! fatty acid anion 8:0
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28837 ! is deprotonated form of octanoic acid

[Term]
id: CHEBI:2567
name: alendronic acid
def: "A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups." []
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:77383 ! 1,1-bis(phosphonic acid)
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50643 ! has role EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0018034 CHEBI:50647 ! is protonated form of alendronate(1-)

[Term]
id: CHEBI:25675
name: oligomycin
def: "Any of the 26-membered ring macrolides produced by <em>Streptomyces</em> species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases." []
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:72600 ! spiroketal
relationship: RO:0000087 CHEBI:20854 ! has role ATP synthase inhibitor
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:25676
name: oligopeptide
def: "A peptide containing a relatively small number of amino acids." []
is_a: CHEBI:16670 ! peptide

[Term]
id: CHEBI:25681
name: omega-3 fatty acid
def: "A family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the ω−3 position, i.e., the third bond from the methyl end of the fatty acid." []
is_a: CHEBI:59549 ! essential fatty acid
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:25693
name: organic heteromonocyclic compound
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:33670 ! heteromonocyclic compound

[Term]
id: CHEBI:25696
name: organic anion
def: "Any organic ion with a net negative charge." []
is_a: CHEBI:22563 ! anion
is_a: CHEBI:25699 ! organic ion

[Term]
id: CHEBI:25697
name: organic cation
def: "Any organic ion with a net positive charge." []
is_a: CHEBI:25699 ! organic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:25698
name: ether
def: "An organooxygen compound with formula ROR, where R is not hydrogen." []
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:25699
name: organic ion
is_a: CHEBI:24870 ! ion
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:25701
name: organic oxide
def: "An oxide in which the oxygen atom is bonded to a carbon atom." []
is_a: CHEBI:25741 ! oxide
is_a: CHEBI:72695 ! organic molecule

[Term]
id: CHEBI:25702
name: organic peroxide
def: "Compounds of structure ROOR' in which R and R' are organic groups." []
is_a: CHEBI:25701 ! organic oxide
is_a: CHEBI:25940 ! peroxides

[Term]
id: CHEBI:25703
name: organic phosphate
is_a: CHEBI:25710 ! organophosphorus compound
is_a: CHEBI:26020 ! phosphate

[Term]
id: CHEBI:25704
name: organic sulfate
def: "Compounds of the general formula SO3HOR where R is an organyl group" []
is_a: CHEBI:26820 ! sulfates
relationship: RO:0018034 CHEBI:58958 ! is protonated form of organosulfate oxoanion

[Term]
id: CHEBI:25705
name: organochlorine insecticide
def: "Any organochlorine pesticide that has been used as an insecticide." []
is_a: CHEBI:38656 ! organochlorine pesticide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide

[Term]
id: CHEBI:25706
name: organomercury compound
def: "A compound containing at least one carbon-mercury bond." []
is_a: CHEBI:25196 ! mercury molecular entity
is_a: CHEBI:25707 ! organometallic compound

[Term]
id: CHEBI:25707
name: organometallic compound
def: "A compound having bonds between one or more metal atoms and one or more carbon atoms of an organyl group." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:25708
name: organophosphate insecticide
is_a: CHEBI:25711 ! organophosphorus insecticide

[Term]
id: CHEBI:2571
name: aliphatic alcohol
def: "An  alcohol derived from an aliphatic compound." []
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:25710
name: organophosphorus compound
def: "An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters." []
is_a: CHEBI:26082 ! phosphorus molecular entity
is_a: CHEBI:33285 ! heteroorganic entity

[Term]
id: CHEBI:25711
name: organophosphorus insecticide
is_a: CHEBI:39093 ! organophosphorus pesticide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide

[Term]
id: CHEBI:25712
name: organoselenium compound
def: "An organoselenium compound is a compound containing at least one carbon-selenium bond." []
is_a: CHEBI:26628 ! selenium molecular entity
is_a: CHEBI:36962 ! organochalcogen compound

[Term]
id: CHEBI:25713
name: organosilicon compound
def: "An organosilicon compound is a compound containing at least one carbon-silicon bond." []
is_a: CHEBI:26677 ! silicon molecular entity
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:25715
name: organothiophosphate insecticide
is_a: CHEBI:25711 ! organophosphorus insecticide

[Term]
id: CHEBI:25716
name: organothiophosphorus compound
def: "An organothiophosphorus compound is an organophosphorus compound which contains a phosphorus-sulfur bond." []
is_a: CHEBI:25710 ! organophosphorus compound
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:25717
name: organotin compound
is_a: CHEBI:25707 ! organometallic compound
is_a: CHEBI:27008 ! tin molecular entity

[Term]
id: CHEBI:25728
name: osmolyte
def: "A solute used by a cell under water stress to maintain cell volume." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:25741
name: oxide
def: "An oxide is a chemical compound of oxygen with other chemical elements." []
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:25750
name: oxime
def: "Compounds of structure R<small><sub>2</sub></small>C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes." []
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: RO:0018034 CHEBI:142513 ! is protonated form of oxime anion

[Term]
id: CHEBI:25754
name: oxo carboxylic acid
def: "Any compound that has an aldehydic or ketonic group as well as a carboxylic acid group in the same molecule." []
is_a: CHEBI:33575 ! carboxylic acid
relationship: RO:0018034 CHEBI:35903 ! is protonated form of oxo carboxylic acid anion

[Term]
id: CHEBI:25798
name: oxopentanoates
def: "The conjugate base of any oxopentanoic acid." []
is_a: CHEBI:35902 ! oxo monocarboxylic acid anion
is_a: CHEBI:59836 ! oxo fatty acid anion
relationship: RO:0018038 CHEBI:31011 ! has functional parent valerate

[Term]
id: CHEBI:25799
name: oxopentanoic acid
def: "A C<small><sub>5</sub></small> fatty acid carrying an oxo group at any position." []
is_a: CHEBI:59644 ! oxo fatty acid
relationship: RO:0018038 CHEBI:17418 ! has functional parent valeric acid

[Term]
id: CHEBI:2580
name: unsaturated fatty acid anion
def: "Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:27208 ! is deprotonated form of unsaturated fatty acid

[Term]
id: CHEBI:25801
name: oxoproline
def: "A pyrrolidinemonocarboxylic acid consisting of proline bearing a single oxo substituent." []
is_a: CHEBI:26273 ! proline derivative
is_a: CHEBI:38275 ! pyrrolidinone
is_a: CHEBI:46701 ! pyrrolidinemonocarboxylic acid

[Term]
id: CHEBI:25805
name: oxygen atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33303 ! chalcogen
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient

[Term]
id: CHEBI:25806
name: oxygen molecular entity
is_a: CHEBI:33304 ! chalcogen molecular entity
relationship: BFO:0000051 CHEBI:25805 ! has part oxygen atom

[Term]
id: CHEBI:25807
name: organooxygen heterocyclic antibiotic
is_a: CHEBI:24531 ! heterocyclic antibiotic

[Term]
id: CHEBI:25810
name: oxopurine
is_a: CHEBI:26401 ! purines

[Term]
id: CHEBI:25812
name: ozone
def: "An elemental molecule with formula O<small><sub>3</sub></small>. An explosive, pale blue gas (b.p. −112°C) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:25362 ! elemental molecule
is_a: CHEBI:26523 ! reactive oxygen species
is_a: CHEBI:33265 ! triatomic oxygen
is_a: CHEBI:36983 ! cyclic pyrimidine nucleotide
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35204 ! has role tracer
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:59739 ! has role electrophilic reagent
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas

[Term]
id: CHEBI:25830
name: p-quinones
def: "A quinone in which the two oxo groups of the quinone are located <em>para</em> to each other on the 6-membered quinonoid ring." []
is_a: CHEBI:36141 ! quinone

[Term]
id: CHEBI:25835
name: hexadecanoate ester
def: "A fatty acid ester obtained by condensation of the carboxy group of palmitic acid with a hydroxy group of an alcohol or phenol." []
is_a: CHEBI:35748 ! fatty acid ester
relationship: RO:0018038 CHEBI:15756 ! has functional parent hexadecanoic acid

[Term]
id: CHEBI:25845
name: pantetheines
is_a: CHEBI:25848 ! pantothenic acids

[Term]
id: CHEBI:25848
name: pantothenic acids
def: "A class of amides formed from pantoic acid and β-alanine and its derivatives." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22823 ! beta-alanine derivative
is_a: CHEBI:37622 ! carboxamide
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:27314 ! has role water-soluble vitamin (role)

[Term]
id: CHEBI:25865
name: penicillanic acids
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:35992 ! penams

[Term]
id: CHEBI:25872
name: pentacyclic triterpenoid
is_a: CHEBI:36615 ! triterpenoid
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:25883
name: pentahydroxyflavone
def: "A hydroxyflavone substituted by five hydroxy groups." []
is_a: CHEBI:24698 ! hydroxyflavone

[Term]
id: CHEBI:25892
name: pentanone
def: "Any ketone that is pentane substituted by an oxo group at unspecified position." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:25900
name: aldopentose phosphate
is_a: CHEBI:35131 ! aldose phosphate
is_a: CHEBI:84055 ! pentose phosphate

[Term]
id: CHEBI:25901
name: pentose
def: "A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose)." []
is_a: CHEBI:35381 ! monosaccharide

[Term]
id: CHEBI:25903
name: peptide antibiotic
def: "A chemically diverse class of peptides that exhibit antimicrobial properties." []
is_a: CHEBI:16670 ! peptide
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:25905
name: peptide hormone
def: "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." []
is_a: CHEBI:16670 ! peptide
relationship: RO:0000087 CHEBI:24621 ! has role hormone

[Term]
id: CHEBI:25940
name: peroxides
def: "Compounds of structure ROOR'." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25741 ! oxide
relationship: BFO:0000051 CHEBI:29369 ! has part peroxy group
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent

[Term]
id: CHEBI:25941
name: peroxynitrite
def: "The nitrogen oxoanion formed by loss of a proton from peroxynitrous acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26523 ! reactive oxygen species
is_a: CHEBI:33458 ! nitrogen oxoanion
is_a: CHEBI:62764 ! reactive nitrogen species
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:25942 ! is deprotonated form of peroxynitrous acid

[Term]
id: CHEBI:25942
name: peroxynitrous acid
is_a: CHEBI:33455 ! nitrogen oxoacid
relationship: RO:0018034 CHEBI:25941 ! is protonated form of peroxynitrite

[Term]
id: CHEBI:25943
name: pesticide synergist
def: "A substance that increases the efficacy of a pesticide." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:25944
name: pesticide
def: "Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:25961
name: phenanthrenes
def: "Any benzenoid aromatic compound that consists of a phenanthrene skeleton and its substituted derivatives thereof." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33836 ! benzenoid aromatic compound
is_a: CHEBI:38032 ! carbotricyclic compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic

[Term]
id: CHEBI:25978
name: phenylacetic acids
def: "Any monocarboxylic acid that is phenylacetic acid or its substituted derivatives." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:25384 ! monocarboxylic acid

[Term]
id: CHEBI:25985
name: phenylalanine derivative
def: "An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of phenylalanine  by a heteroatom. The definition normally excludes peptides containing phenylalanine  residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:28044 ! has functional parent phenylalanine

[Term]
id: CHEBI:25990
name: phenylethanolamines
def: "An ethanolamine compound having a phenyl (substituted or unsubstituted) group on the carbon bearing the hydroxy substituent." []
is_a: CHEBI:23981 ! ethanolamines

[Term]
id: CHEBI:25996
name: phenylhydrazines
def: "Any member of the class of  hydrazines carrying a phenyl substituent." []
is_a: CHEBI:24631 ! hydrazines

[Term]
id: CHEBI:26004
name: phenylpropanoid
def: "Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin." []
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:26013
name: pheromone
def: "A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour." []
is_a: CHEBI:26645 ! semiochemical

[Term]
id: CHEBI:26020
name: phosphate
def: "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." []
is_a: CHEBI:26079 ! phosphoric acid derivative

[Term]
id: CHEBI:26043
name: phosphinic ester
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:26045
name: phosphite ion
is_a: CHEBI:33461 ! phosphorus oxoanion

[Term]
id: CHEBI:26066
name: phosphonate
is_a: CHEBI:37588 ! phosphonic acid derivative

[Term]
id: CHEBI:26069
name: phosphonic acids
def: "HP(=O)(OH)<small><sub>2</sub></small>  (phosphonic acid) and its P-substituted derivatives." []
is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives

[Term]
id: CHEBI:26078
name: phosphoric acid
def: "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." []
is_a: CHEBI:59698 ! phosphoric acids
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:39745 ! is protonated form of dihydrogenphosphate

[Term]
id: CHEBI:26079
name: phosphoric acid derivative
is_a: CHEBI:36359 ! phosphorus oxoacid derivative
relationship: RO:0018038 CHEBI:26078 ! has functional parent phosphoric acid

[Term]
id: CHEBI:26082
name: phosphorus molecular entity
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: BFO:0000051 CHEBI:28659 ! has part phosphorus atom

[Term]
id: CHEBI:26087
name: photosynthetic electron-transport chain inhibitor
is_a: CHEBI:24527 ! herbicide
is_a: CHEBI:38496 ! electron-transport chain inhibitor

[Term]
id: CHEBI:26088
name: photosystem-I inhibitor
is_a: CHEBI:26087 ! photosynthetic electron-transport chain inhibitor

[Term]
id: CHEBI:26089
name: photosystem-II inhibitor
is_a: CHEBI:26087 ! photosynthetic electron-transport chain inhibitor

[Term]
id: CHEBI:26092
name: phthalate
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:29067 ! carboxylic acid anion

[Term]
id: CHEBI:26094
name: benzenedicarboxylic acid
def: "A member of the class of benzoic acids in that consists of benzene substituted by two carboxy groups (A closed class)." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:35692 ! dicarboxylic acid

[Term]
id: CHEBI:26106
name: phylloquinones
is_a: CHEBI:26127 ! phytylnaphthoquinone
is_a: CHEBI:26255 ! prenylquinone

[Term]
id: CHEBI:26115
name: phytoalexin
def: "A toxin made by a plant that acts against an organism attacking it." []
is_a: CHEBI:38231 ! phytotoxin

[Term]
id: CHEBI:26124
name: phytosteroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:26125
name: phytosterols
def: "Sterols similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond." []
is_a: CHEBI:15889 ! sterol
is_a: CHEBI:26124 ! phytosteroid

[Term]
id: CHEBI:26127
name: phytylnaphthoquinone
is_a: CHEBI:25481 ! naphthoquinone

[Term]
id: CHEBI:26130
name: biological pigment
def: "An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light." []
is_a: CHEBI:52208 ! biophysical role

[Term]
id: CHEBI:26144
name: piperazines
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:26151
name: piperidines
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:26155
name: plant growth regulator
def: "A chemical, natural or artificial, that can affect the rate of growth of a plant." []
is_a: CHEBI:39317 ! growth regulator

[Term]
id: CHEBI:26167
name: polar amino acid
def: "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." []
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018036 CHEBI:62031 ! is tautomer of polar amino acid zwitterion

[Term]
id: CHEBI:26177
name: polyene antibiotic
def: "A family of antibiotics containing a conjugated polyene moiety, usuallly isolated from some species of <em>Streptomyces</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33822 ! organic hydroxy compound
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:26178
name: polyester macromolecule
def: "A macromolecule composed of units connected by carboxylic ester (-O-CO-) linkages." []
is_a: CHEBI:33839 ! macromolecule
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:26179
name: polyether antibiotic
is_a: CHEBI:25807 ! organooxygen heterocyclic antibiotic

[Term]
id: CHEBI:26188
name: polyketide
def: "Natural and synthetic compounds containing alternating carbonyl and methylene groups ('β-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides." []
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:26191
name: polyol
def: "A compound that contains two or more hydroxy groups." []
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:26195
name: polyphenol
def: "Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group." []
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:26196
name: polyphenylpropanoid
is_a: CHEBI:26004 ! phenylpropanoid

[Term]
id: CHEBI:26199
name: polyprenol
def: "Any member of the class of  prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units." []
is_a: CHEBI:26244 ! prenols

[Term]
id: CHEBI:26208
name: polyunsaturated fatty acid
def: "Any fatty acid containing more than one double bond. Acids in this group are reported to have cardioprotective effects; and levels are lowered in chronic fatigue syndrome." []
is_a: CHEBI:27208 ! unsaturated fatty acid
relationship: RO:0018034 CHEBI:76567 ! is protonated form of polyunsaturated fatty acid anion

[Term]
id: CHEBI:26214
name: porphyrins
def: "Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the α-positions by four methine groups to form a macrocyclic structure." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36309 ! cyclic tetrapyrrole
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:26216
name: potassium atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22314 ! alkali metal atom
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite

[Term]
id: CHEBI:26217
name: potassium molecular entity
is_a: CHEBI:33296 ! alkali metal molecular entity
relationship: BFO:0000051 CHEBI:26216 ! has part potassium atom

[Term]
id: CHEBI:26218
name: potassium salt
def: "Any alkali metal salt having potassium(1+) as the cation." []
is_a: CHEBI:26217 ! potassium molecular entity
is_a: CHEBI:35479 ! alkali metal salt
relationship: BFO:0000051 CHEBI:29103 ! has part potassium(1+)

[Term]
id: CHEBI:26220
name: precocenes
is_a: CHEBI:24941 ! juvenile hormone antagonists

[Term]
id: CHEBI:26244
name: prenols
def: "Any alcohol possessing the general formula H-[CH<small><sub>2</sub></small>C(Me)=CHCH<small><sub>2</sub></small>]<small><sub><em>n</em></sub></small>OH in which the carbon skeleton is composed of one or more isoprene units (biogenetic precursors of the isoprenoids)." []
is_a: CHEBI:24913 ! isoprenoid
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:26254
name: prenylnaphthoquinone
def: "Any napthoquinone that is substituted at position 2 by a prenyl or polyprenyl group. The term also includes compounds that are functionalised on the prenyl or polyprenyl chain (e.g. by a hydroxy group)." []
is_a: CHEBI:25481 ! naphthoquinone
is_a: CHEBI:26255 ! prenylquinone

[Term]
id: CHEBI:26255
name: prenylquinone
def: "A quinone substituted by a polyprenyl-derived side-chain. Prenylquinones occur in all living cells. Due to their amphiphilic character, they are mainly located in biological membranes where they function as electron and proton carriers in the photosynthetic and respiratory electron transport chains. Some prenylquinones also perform more specialised roles sucy as antioxidants and enzyme cofactors. Prenylquinones are classified according to ring structure: the main classes are menaquinones, phylloquinones, ubiquinones and plastoquinones." []
is_a: CHEBI:25830 ! p-quinones

[Term]
id: CHEBI:26267
name: proanthocyanidin
def: "A flavonoid oligomer obtained by the the condensation of two or more units of hydroxyflavans." []
is_a: CHEBI:26848 ! tannin
is_a: CHEBI:72720 ! flavonoid oligomer
relationship: RO:0018038 CHEBI:72010 ! has functional parent hydroxyflavan

[Term]
id: CHEBI:26271
name: proline
def: "An α-amino acid that is pyrrolidine bearing a carboxy substituent at position 2." []
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:38260 ! pyrrolidines
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32872 ! is deprotonated form of prolinium
relationship: RO:0018034 CHEBI:32871 ! is protonated form of prolinate

[Term]
id: CHEBI:26273
name: proline derivative
def: "An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:26271 ! has functional parent proline

[Term]
id: CHEBI:26276
name: prometryn
def: "A diamino-1,3,5-triazine that is <em>N</em>,<em>N</em>'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine substituted by a methylsulfanediyl group at position 6." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38174 ! methylthio-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:26279
name: propan-1-ols
def: "A primary alcohol based on a propan-1-ol skeleton and its substituted derivatives." []
is_a: CHEBI:15734 ! primary alcohol

[Term]
id: CHEBI:26282
name: propanals
def: "An aldehyde based on a propanal skeleton and its derivatives." []
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:26284
name: propane-1,2-diols
is_a: CHEBI:26288 ! propanediol

[Term]
id: CHEBI:26288
name: propanediol
is_a: CHEBI:13643 ! glycol

[Term]
id: CHEBI:26292
name: propanones
def: "A ketone that is propane carrying at least one oxo substituent." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:2630
name: hydramethylnon
def: "A member of the class of hydrazones that is used as an insecticide for control of ants and cockroaches." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:38532 ! hydrazone
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:78840 ! olefinic compound
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:38499 ! has role mitochondrial cytochrome-bc1 complex inhibitor

[Term]
id: CHEBI:26300
name: propenol
is_a: CHEBI:15734 ! primary alcohol

[Term]
id: CHEBI:26307
name: propionitrile
def: "A nitrile that is acrylonitrile in which the carbon-carbon double bond has been reduced to a single bond." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:80291 ! aliphatic nitrile
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent

[Term]
id: CHEBI:26313
name: propynol
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:15734 ! primary alcohol

[Term]
id: CHEBI:26333
name: prostaglandin
def: "Naturally occurring compounds derived from the parent C<small><sub>20</sub></small> acid, prostanoic acid." []
is_a: CHEBI:26347 ! prostanoid
relationship: RO:0018034 CHEBI:59326 ! is protonated form of prostaglandin carboxylic acid anion
relationship: RO:0018038 CHEBI:8504 ! has functional parent prostanoic acid

[Term]
id: CHEBI:26337
name: prostaglandins D
is_a: CHEBI:26333 ! prostaglandin
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:36132 ! alicyclic ketone

[Term]
id: CHEBI:26338
name: prostaglandins E
is_a: CHEBI:26333 ! prostaglandin
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:3992 ! cyclic ketone

[Term]
id: CHEBI:2634
name: amidine
def: "Derivatives of oxoacids R<small><sub><em>n</em></sub></small>E(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine." []
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:26340
name: prostaglandins F
is_a: CHEBI:26333 ! prostaglandin

[Term]
id: CHEBI:26345
name: prostaglandins I
is_a: CHEBI:26333 ! prostaglandin
is_a: CHEBI:47783 ! cyclopentafuran

[Term]
id: CHEBI:26347
name: prostanoid
def: "The family of natural prostaglandins and prostaglandin-like compounds including prostacyclins and thromboxanes." []
is_a: CHEBI:23899 ! icosanoid
relationship: RO:0018034 CHEBI:62943 ! is protonated form of prostanoid anion

[Term]
id: CHEBI:26348
name: prosthetic group
def: "A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity." []
is_a: CHEBI:23357 ! cofactor

[Term]
id: CHEBI:26369
name: psoralens
def: "A furanocoumarin with a 7<em>H</em>-furo[3,2-<em>g</em>]chromen-7-one skeleton and its substituted derivatives thereof." []
is_a: CHEBI:24128 ! furanocoumarin

[Term]
id: CHEBI:26373
name: pteridines
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:33833 ! heteroarene
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:26375
name: pterins
is_a: CHEBI:26373 ! pteridines

[Term]
id: CHEBI:26384
name: pullulans
is_a: CHEBI:24384 ! glycogens

[Term]
id: CHEBI:26385
name: purine alkaloid
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:26401 ! purines

[Term]
id: CHEBI:26386
name: purine nucleobase
def: "A nucleobase whose skeleton is derived from purine." []
is_a: CHEBI:18282 ! nucleobase
is_a: CHEBI:26401 ! purines

[Term]
id: CHEBI:2639
name: amiloride
def: "A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid." []
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38314 ! pyrazines
relationship: RO:0000087 CHEBI:35498 ! has role diuretic
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38633 ! has role sodium channel blocker
relationship: RO:0018033 CHEBI:84745 ! is deprotonated form of amiloride(1+)

[Term]
id: CHEBI:26391
name: purine nucleoside diphosphate
is_a: CHEBI:16862 ! nucleoside 5'-diphosphate

[Term]
id: CHEBI:26392
name: purine nucleoside monophosphate
is_a: CHEBI:17188 ! nucleoside 5'-monophosphate

[Term]
id: CHEBI:26393
name: purine nucleoside triphosphate
is_a: CHEBI:17326 ! nucleoside 5'-triphoshate

[Term]
id: CHEBI:26394
name: purine nucleoside
is_a: CHEBI:26401 ! purines
is_a: CHEBI:33838 ! nucleoside

[Term]
id: CHEBI:26395
name: purine nucleotide
def: "Any nucleotide that has a purine nucleobase." []
is_a: CHEBI:26401 ! purines
is_a: CHEBI:36976 ! nucleotide

[Term]
id: CHEBI:26396
name: purine ribonucleoside diphosphate
is_a: CHEBI:17668 ! ribonucleoside diphosphat
is_a: CHEBI:26391 ! purine nucleoside diphosphate

[Term]
id: CHEBI:26397
name: purine ribonucleoside monophosphate
is_a: CHEBI:26392 ! purine nucleoside monophosphate
is_a: CHEBI:26558 ! ribonucleoside monophosphate

[Term]
id: CHEBI:26398
name: purine ribonucleoside triphosphate
is_a: CHEBI:17972 ! ribonucleoside triphosphate
is_a: CHEBI:26393 ! purine nucleoside triphosphate

[Term]
id: CHEBI:26399
name: purine ribonucleoside
def: "A ribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration)." []
is_a: CHEBI:18254 ! ribonucleoside
is_a: CHEBI:26394 ! purine nucleoside

[Term]
id: CHEBI:26400
name: purine ribonucleotide
def: "Any ribonucleotide that has a purine nucleobase." []
is_a: CHEBI:26395 ! purine nucleotide
is_a: CHEBI:26561 ! ribonucleotide

[Term]
id: CHEBI:26401
name: purines
def: "A class of imidazopyrimidines that consists of purine and its substituted derivatives." []
is_a: CHEBI:35875 ! imidazopyrimidine

[Term]
id: CHEBI:26407
name: pyrans
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:26409
name: pyrazole insecticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38601 ! pyrazole pesticide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide

[Term]
id: CHEBI:26410
name: pyrazoles
is_a: CHEBI:23677 ! diazole

[Term]
id: CHEBI:26413
name: pyrethroid insecticide
is_a: CHEBI:24852 ! insecticide
is_a: CHEBI:39000 ! sodium channel modulator

[Term]
id: CHEBI:26414
name: pyridazinone
is_a: CHEBI:37921 ! pyridazines

[Term]
id: CHEBI:26416
name: pyridine alkaloid
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:26420
name: pyridinemonocarboxylic acid
def: "A monocarboxylic acid in which the carboxy group is attached to a pyridine (or substituted pyridine) ring." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:33859 ! aromatic carboxylic acid
relationship: RO:0018034 CHEBI:38181 ! is protonated form of pyridinemonocarboxylate

[Term]
id: CHEBI:26421
name: pyridines
def: "Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:26432
name: pyrimidine nucleobase
def: "A nucleobase whose skeleton is derived from pyrimidine." []
is_a: CHEBI:18282 ! nucleobase
is_a: CHEBI:39447 ! pyrimidines

[Term]
id: CHEBI:26438
name: pyrimidine nucleoside monophosphate
is_a: CHEBI:17188 ! nucleoside 5'-monophosphate

[Term]
id: CHEBI:26440
name: pyrimidine nucleoside
is_a: CHEBI:33838 ! nucleoside
is_a: CHEBI:39447 ! pyrimidines

[Term]
id: CHEBI:26441
name: pyrimidine nucleotide
is_a: CHEBI:36976 ! nucleotide
is_a: CHEBI:39447 ! pyrimidines

[Term]
id: CHEBI:26443
name: pyrimidine ribonucleoside monophosphate
is_a: CHEBI:26438 ! pyrimidine nucleoside monophosphate
is_a: CHEBI:26558 ! ribonucleoside monophosphate

[Term]
id: CHEBI:26446
name: pyrimidine ribonucleotide
is_a: CHEBI:26441 ! pyrimidine nucleotide
is_a: CHEBI:26561 ! ribonucleotide

[Term]
id: CHEBI:26455
name: pyrroles
def: "An azole that includes only one N atom and no other heteroatom as a part of the aromatic skeleton." []
is_a: CHEBI:68452 ! azole

[Term]
id: CHEBI:26456
name: pyrrolidine alkaloid
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:38260 ! pyrrolidines

[Term]
id: CHEBI:26463
name: pyruvate family amino acid
def: "An <small>L</small>-α-amino acid which is biosynthesised from pyruvate (i.e. alanine, valine, and leucine). A closed class." []
is_a: CHEBI:15705 ! L-alpha-amino acid
is_a: CHEBI:83813 ! proteinogenic amino acid

[Term]
id: CHEBI:26469
name: quaternary nitrogen compound
def: "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen." []
is_a: CHEBI:35352 ! organonitrogen compound
relationship: BFO:0000051 CHEBI:35267 ! has part quaternary ammonium ion

[Term]
id: CHEBI:26490
name: quinate
def: "A cyclitol carboxylic acid anion that is conjugate base of quinic acid." []
is_a: CHEBI:36125 ! cyclitol carboxylic acid anion
relationship: RO:0018033 CHEBI:26493 ! is deprotonated form of quinic acid

[Term]
id: CHEBI:26493
name: quinic acid
def: "A cyclitol carboxylic acid." []
is_a: CHEBI:36123 ! cyclitol carboxylic acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:26490 ! is protonated form of quinate

[Term]
id: CHEBI:26508
name: quinoline N-oxide
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:35580 ! N-oxide

[Term]
id: CHEBI:26509
name: quinoline alkaloid
is_a: CHEBI:22315 ! alkaloid

[Term]
id: CHEBI:26512
name: quinolinemonocarboxylic acid
def: "Any aromatic carboxylic acid that contains a quinoline moiety that is substituted by one carboxy substituent." []
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:33859 ! aromatic carboxylic acid
relationship: RO:0018034 CHEBI:38773 ! is protonated form of quinolinemonocarboxylate

[Term]
id: CHEBI:26513
name: quinolines
def: "A class of aromatic heterocyclic compounds each of which contains a benzene ring <em>ortho</em> fused to carbons 2 and 3 of a pyridine ring." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:26519
name: radical
def: "A molecular entity possessing an unpaired electron." []
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:26523
name: reactive oxygen species
def: "Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." []
is_a: CHEBI:25806 ! oxygen molecular entity

[Term]
id: CHEBI:26534
name: retinals
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:26537 ! retinoid

[Term]
id: CHEBI:26536
name: retinoic acid
def: "A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified)." []
is_a: CHEBI:26537 ! retinoid
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:15036 ! is protonated form of retinoate

[Term]
id: CHEBI:26537
name: retinoid
def: "Oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof." []
is_a: CHEBI:23849 ! diterpenoid
relationship: RO:0018034 CHEBI:139589 ! is protonated form of retinoid anion

[Term]
id: CHEBI:26546
name: rhamnose
def: "A deoxymannose sugar that is the 6-deoxy derivative of hexose." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33983 ! deoxymannose
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:26548
name: rhamnosylglucoside
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:26556
name: 1-ribosylimidazolecarboxamide
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:37293 ! 1-ribosylimidazole

[Term]
id: CHEBI:26558
name: ribonucleoside monophosphate
is_a: CHEBI:17188 ! nucleoside 5'-monophosphate
relationship: RO:0018034 CHEBI:63165 ! is protonated form of ribonucleoside monophosphate oxoanion

[Term]
id: CHEBI:26561
name: ribonucleotide
is_a: CHEBI:26562 ! ribose phosphate
is_a: CHEBI:36976 ! nucleotide

[Term]
id: CHEBI:26562
name: ribose phosphate
is_a: CHEBI:25900 ! aldopentose phosphate

[Term]
id: CHEBI:26580
name: rifamycins
is_a: CHEBI:22565 ! ansamycin
is_a: CHEBI:39270 ! naphthofuran

[Term]
id: CHEBI:26587
name: rutinoside
is_a: CHEBI:26548 ! rhamnosylglucoside

[Term]
id: CHEBI:26588
name: 1,3,5-triazines
def: "Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure." []
is_a: CHEBI:38102 ! triazines

[Term]
id: CHEBI:26596
name: salicylates
def: "Any salt or ester arising from reaction of the carboxy group of salicylic acid, or any ester resulting from the condensation of the phenolic hydroxy group of salicylic acid with an organic acid." []
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:26605
name: saponin
def: "A glycoside that is a compound containing one or more hydrophilic glycoside moieties combined with a lipophilic triterpenoid or steroid derivative. Found in particular abundance in plant species." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24400 ! glycoside
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018038 CHEBI:26606 ! has functional parent sapogenin

[Term]
id: CHEBI:26606
name: sapogenin
def: "Any organic polycyclic compound that is the aglycon moiety of a saponin; sapogenins may be steroids or triterpenoids." []
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:26607
name: saturated fatty acid
def: "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." []
is_a: CHEBI:35366 ! fatty acid

[Term]
id: CHEBI:26628
name: selenium molecular entity
is_a: CHEBI:33304 ! chalcogen molecular entity
relationship: BFO:0000051 CHEBI:27568 ! has part selenium atom

[Term]
id: CHEBI:26629
name: selenoamino acid
is_a: CHEBI:25712 ! organoselenium compound

[Term]
id: CHEBI:26643
name: aldehydic acid
def: "A monocarboxylic acid derived from any dicarboxylic acid that has a retained name by the formal reduction of one of the carboxy groups to a formyl group. The resulting structure, also known as a semialdehyde, may be named by replacing the ending '...ic acid' of the retained name of the dicarboxylic acid by the ending '...aldehydic acid'. Aldehydic acids therefore contain one carboxy group and one aldehyde group." []
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0018034 CHEBI:71944 ! is protonated form of aldehydic acid anion

[Term]
id: CHEBI:26645
name: semiochemical
def: "A molecular messenger released by an organism that affects the behaviour within or between species." []
is_a: CHEBI:33280 ! molecular messenger

[Term]
id: CHEBI:26649
name: serine derivative
def: "An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:17822 ! has functional parent serine

[Term]
id: CHEBI:2665
name: amitraz
def: "A tertiary amino compound that is 1,3,5-triazapenta-1,4-diene substituted by a methyl group at position 3 and 2,4-dimethylphenyl groups at positions 1 and 5." []
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:51917 ! formamidines
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:26650
name: serine family amino acid
def: "An α-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class." []
is_a: CHEBI:33704 ! alpha-amino acid

[Term]
id: CHEBI:26658
name: sesquiterpenoid
def: "Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." []
is_a: CHEBI:26873 ! terpenoid
relationship: RO:0018040 CHEBI:35189 ! has parent hydride sesquiterpene

[Term]
id: CHEBI:2666
name: amitriptyline
def: "An organic tricyclic compound that is 10,11-dihydro-5<em>H</em>-dibenzo[<em>a,d</em>][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5." []
is_a: CHEBI:32876 ! tertiary amine
is_a: CHEBI:38032 ! carbotricyclic compound
relationship: RO:0000087 CHEBI:140489 ! has role tropomyosin-related kinase B receptor agonist
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018040 CHEBI:35642 ! has parent hydride dibenzo[a,d][7]annulene

[Term]
id: CHEBI:26666
name: short-chain fatty acid
def: "An aliphatic monocarboxylic acid with a chain length of less than C<small><sub>6</sub></small>. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:58951 ! is protonated form of short-chain fatty acid anion

[Term]
id: CHEBI:26672
name: siderophore
def: "Any of low-molecular-mass iron(III)-chelating compounds produced by microorganisms for the purpose of the transport and sequestration of iron." []
is_a: CHEBI:23357 ! cofactor
is_a: CHEBI:24028 ! iron(3+) chelator
is_a: CHEBI:24874 ! iron ionophore

[Term]
id: CHEBI:26677
name: silicon molecular entity
is_a: CHEBI:33582 ! carbon group molecular entity
relationship: BFO:0000051 CHEBI:27573 ! has part silicon atom

[Term]
id: CHEBI:2668
name: amlodipine
def: "A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina." []
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:50075 ! dihydropyridine
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:26689
name: singlet dioxygen
def: "A reactive oxygen species that is the lowest excited state of the dioxygen molecule." []
is_a: CHEBI:15379 ! dioxygen
is_a: CHEBI:26523 ! reactive oxygen species
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:26706
name: sn-glycerol 3-phosphates
is_a: CHEBI:26707 ! glycerol phosphate

[Term]
id: CHEBI:26707
name: glycerol phosphate
is_a: CHEBI:22297 ! alditol phosphate
relationship: RO:0018038 CHEBI:17754 ! has functional parent glycerol

[Term]
id: CHEBI:26708
name: sodium atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22314 ! alkali metal atom
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite

[Term]
id: CHEBI:26709
name: sodium hydrogensulfite
def: "An inorganic sodium salt having hydrogensulfite as the counterion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38702 ! inorganic sodium salt
is_a: CHEBI:48857 ! sulfite salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: BFO:0000051 CHEBI:17137 ! has part hydrogensulfite
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:63247 ! has role reducing agent
relationship: RO:0000087 CHEBI:77962 ! has role food antioxidant
relationship: RO:0000087 CHEBI:78006 ! has role food colour retention agent

[Term]
id: CHEBI:26710
name: sodium chloride
def: "An inorganic chloride salt having sodium(1+) as the counterion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36093 ! inorganic chloride
is_a: CHEBI:38702 ! inorganic sodium salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:149552 ! has role emetic
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76916 ! has role hyperglycemic agent
relationship: RO:0000087 CHEBI:79314 ! has role flame retardant

[Term]
id: CHEBI:26712
name: sodium molecular entity
is_a: CHEBI:33296 ! alkali metal molecular entity
relationship: BFO:0000051 CHEBI:26708 ! has part sodium atom

[Term]
id: CHEBI:26714
name: sodium salt
def: "Any alkali metal salt having sodium(1+) as the cation." []
is_a: CHEBI:26712 ! sodium molecular entity
is_a: CHEBI:35479 ! alkali metal salt
relationship: BFO:0000051 CHEBI:29101 ! has part sodium(1+)

[Term]
id: CHEBI:26738
name: sphingenine
def: "A 2-aminooctadecene-1,3-diol having (2<i>S</i>,3<i>R</i>)-configuration." []
is_a: CHEBI:46963 ! 2-aminooctadecene-1,3-diol

[Term]
id: CHEBI:26739
name: sphingolipid
def: "Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:26743
name: sphing-4-enine
def: "A sphingenine in which the C=C double bond is located at the 4-position." []
is_a: CHEBI:26738 ! sphingenine
is_a: CHEBI:46964 ! 2-aminooctadec-4-ene-1,3-diol
relationship: RO:0018039 CHEBI:46965 ! is enantiomer of (2R,3S)-2-aminooctadec-4-ene-1,3-diol

[Term]
id: CHEBI:26745
name: spirostan
is_a: CHEBI:35508 ! steroid fundamental parent
is_a: CHEBI:37948 ! oxaspiro compound

[Term]
id: CHEBI:2676
name: amoxicillin
def: "A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group." []
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:88187 ! penicillin allergen
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018034 CHEBI:51256 ! is protonated form of amoxicillin(1-)

[Term]
id: CHEBI:26764
name: steroid hormone
def: "Any steroid that acts as hormone." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35341 ! steroid
relationship: RO:0000087 CHEBI:24621 ! has role hormone

[Term]
id: CHEBI:26766
name: steroid lactone
is_a: CHEBI:25000 ! lactone
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:26775
name: stilbene
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:26776
name: stilbenoid
def: "Any olefinic compound characterised by a 1,2-diphenylethylene backbone." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:26788
name: streptomycins
is_a: CHEBI:22479 ! amino cyclitol glycoside
is_a: CHEBI:22507 ! aminoglycoside antibiotic

[Term]
id: CHEBI:2679
name: amphetamine
def: "A racemate comprising equimolar amounts of (<i>R</i>)-amphetamine (also known as levamphetamine or levoamphetamine) and (<i>S</i>)-amphetamine (also known as dexamfetamine or dextroamphetamine." []
is_a: CHEBI:35338 ! amphetamines
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:42724 ! has part (R)-amphetamine
relationship: BFO:0000051 CHEBI:4469 ! has part (S)-amphetamine
relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:51039 ! has role dopamine uptake inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:26799
name: styrenes
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:26806
name: succinate
def: "A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of succinic acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion

[Term]
id: CHEBI:26816
name: carbohydrate phosphate
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:37734 ! phosphoric ester
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:26819
name: sulfuric ester
def: "An ester of an alcohol and sulfuric acid." []
is_a: CHEBI:35701 ! ester
is_a: CHEBI:37826 ! sulfuric acid derivative

[Term]
id: CHEBI:2682
name: amphotericin B
def: "A macrolide antibiotic used to treat potentially life-threatening fungal infections." []
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:26177 ! polyene antibiotic
is_a: CHEBI:61355 ! 3-hydroxy carboxylic acid
is_a: CHEBI:87113 ! antibiotic antifungal drug
relationship: RO:0000087 CHEBI:171664 ! has role antiamoebic agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:26820
name: sulfates
def: "Salts and esters of sulfuric acid" []
is_a: CHEBI:37826 ! sulfuric acid derivative

[Term]
id: CHEBI:26822
name: sulfide
def: "Any sulfur molecular entity that involves either covalently bonded or anionic sulfur." []
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:26823
name: sulfites
def: "Any sulfurous acid derivative that is a salt or an ester of sulfurous acid." []
is_a: CHEBI:39087 ! sulfurous acid derivative

[Term]
id: CHEBI:26830
name: sulfonium compound
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:26833
name: sulfur atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33303 ! chalcogen
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient

[Term]
id: CHEBI:26834
name: sulfur-containing amino acid
is_a: CHEBI:33576 ! sulfur-containing carboxylic acid
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018034 CHEBI:63470 ! is protonated form of sulfur-containing amino-acid anion

[Term]
id: CHEBI:26835
name: sulfur molecular entity
is_a: CHEBI:33304 ! chalcogen molecular entity
relationship: BFO:0000051 CHEBI:26833 ! has part sulfur atom

[Term]
id: CHEBI:26836
name: sulfuric acid
def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." []
is_a: CHEBI:33402 ! sulfur oxoacid
relationship: RO:0000087 CHEBI:35223 ! has role catalyst
relationship: RO:0018034 CHEBI:45696 ! is protonated form of hydrogensulfate

[Term]
id: CHEBI:26841
name: synthetic auxin
def: "A synthetic compound exhibiting auxin activity." []
is_a: CHEBI:22676 ! auxin
is_a: CHEBI:35703 ! xenobiotic

[Term]
id: CHEBI:26848
name: tannin
def: "Any of a group of astringent polyphenolic vegetable principles or compounds, chiefly complex glucosides of catechol and pyrogallol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26195 ! polyphenol
relationship: RO:0000087 CHEBI:74783 ! has role astringent

[Term]
id: CHEBI:26849
name: DL-tartaric acid
def: "A racemate comprising equimolar amounts of <small>D</small>- and <small>L</small>-tartaric acid." []
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:15671 ! has part L-tartaric acid
relationship: BFO:0000051 CHEBI:15672 ! has part D-tartaric acid
relationship: RO:0018034 CHEBI:35397 ! is protonated form of DL-tartrate(1-)

[Term]
id: CHEBI:26872
name: terpene ketone
def: "Any terpenoid which contains a keto group." []
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:26873 ! terpenoid

[Term]
id: CHEBI:26873
name: terpenoid
def: "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." []
is_a: CHEBI:24913 ! isoprenoid
relationship: RO:0018040 CHEBI:35186 ! has parent hydride terpene

[Term]
id: CHEBI:26878
name: tertiary alcohol
def: "A tertiary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it." []
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:26888
name: tetrachlorobenzene
def: "Any member of the class of chlorobenzenes carrying four chloro groups at unspecified positions." []
is_a: CHEBI:23132 ! chlorobenzenes

[Term]
id: CHEBI:26893
name: tetracyclic triterpenoid
def: "Any triterpenoid consisting of a tetracyclic skeleton." []
is_a: CHEBI:177333 ! organic tetracyclic compound
is_a: CHEBI:36615 ! triterpenoid

[Term]
id: CHEBI:26895
name: tetracyclines
def: "A subclass of polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26188 ! polyketide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018040 CHEBI:32600 ! has parent hydride tetracene

[Term]
id: CHEBI:26907
name: tetrahydrofolic acid
def: "A group of heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with one or more <small>L</small>-glutamic acid units." []
is_a: CHEBI:37445 ! folic acids
relationship: RO:0018034 CHEBI:67016 ! is protonated form of tetrahydrofolate

[Term]
id: CHEBI:26911
name: oxolane
def: "A cyclic ether that is butane in which one hydrogen from each methyl group is substituted by an oxygen." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:26912 ! oxolanes
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:37407 ! cyclic ether
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent

[Term]
id: CHEBI:26912
name: oxolanes
def: "Any oxacycle having an oxolane (tetrahydrofuran) skeleton." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:26921
name: tetrahydropyridine
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:26932
name: tetrapyrrole
def: "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." []
is_a: CHEBI:33833 ! heteroarene
is_a: CHEBI:38077 ! polypyrrole

[Term]
id: CHEBI:26933
name: tetraric acid
is_a: CHEBI:22290 ! aldaric acid
is_a: CHEBI:66873 ! C4-dicarboxylic acid
relationship: RO:0018034 CHEBI:33798 ! is protonated form of tetraric acid anion

[Term]
id: CHEBI:26935
name: tetraterpenoid
def: "Any terpenoid derived from a tetraterpene. The term includes compounds in which the C40 skeleton of the parent tetraterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." []
is_a: CHEBI:26873 ! terpenoid
relationship: RO:0018040 CHEBI:35193 ! has parent hydride tetraterpene

[Term]
id: CHEBI:26948
name: vitamin B1
def: "Any member of the group of 1,3-thiazolium cations that exhibit biological activity against vitamin B<small><sub>1</sub></small> deficiency in animals. Symptoms of vitamin B<small><sub>1</sub></small> deficiency include constipation, loss of apetite, fatigue, nausea, delirium, blurry vision and muscle weakness. Severe vitamin B<small><sub>1</sub></small> deficiency can also lead to a disease known as <a href=\"https://en.wikipedia.org/wiki/Thiamine_deficiency\" target=\"_blank\">beriberi</a>. Vitamin B<small><sub>1</sub></small> consists of the vitamer thiamin and its acid, aldehyde and phosphorylated derivatives (and their corresponding ionized, salt and hydrate forms)." []
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:63048 ! 1,3-thiazolium cation
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:26952
name: thioacetic acid
is_a: CHEBI:35737 ! monothiocarboxylic acid
relationship: RO:0018034 CHEBI:30320 ! is protonated form of thioacetate

[Term]
id: CHEBI:26959
name: thiocarboxylic ester
def: "An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:26961
name: thiophenes
def: "Compounds containing at least one thiophene ring." []
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:26979
name: organic heterotricyclic compound
def: "An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms." []
is_a: CHEBI:36688 ! heterotricyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound
is_a: CHEBI:51959 ! organic tricyclic compound

[Term]
id: CHEBI:26986
name: threonine
def: "An α-amino acid in which one of the hydrogens attached to the α-carbon of glycine is substituted by a 1-hydroxyethyl group." []
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:38263 ! 2-amino-3-hydroxybutanoic acid
relationship: BFO:0000051 CHEBI:50341 ! has part 1-hydroxyethyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32833 ! is deprotonated form of threoninium
relationship: RO:0018034 CHEBI:32832 ! is protonated form of threoninate

[Term]
id: CHEBI:26987
name: threonine derivative
def: "An amino acid derivative resulting from reaction of threonine at the amino group or the carboxy group, or from the replacement of any hydrogen of threonine by a heteroatom. The definition normally excludes peptides containing threonine residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:26986 ! has functional parent threonine

[Term]
id: CHEBI:27007
name: tin atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:233500 ! post-transition metal atom
is_a: CHEBI:33306 ! carbon group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:27008
name: tin molecular entity
is_a: CHEBI:33582 ! carbon group molecular entity
relationship: BFO:0000051 CHEBI:27007 ! has part tin atom

[Term]
id: CHEBI:27013
name: tocopherol
def: "A collective name for a group of closely related lipids that contain a chroman-6-ol nucleus substituted at position 2 by a methyl group and by a saturated hydrocarbon chain consisting of three isoprenoid units. They are designated as α-, β-, γ-, and δ-tocopherol depending on the number and position of additional methyl substituents on the aromatic ring. Tocopherols occur in vegetable oils and vegetable oil products, almost exclusively with <i>R</i>,<i>R</i>,<i>R</i> configuration. Tocotrienols differ from tocopherols only in having three double bonds in the hydrocarbon chain." []
is_a: CHEBI:39437 ! tocol

[Term]
id: CHEBI:27021
name: toluate
is_a: CHEBI:22718 ! benzoates

[Term]
id: CHEBI:27024
name: toluenes
def: "Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group." []
is_a: CHEBI:22712 ! benzenes

[Term]
id: CHEBI:27026
name: toxin
def: "Poisonous substance produced by a biological organism such as a microbe, animal or plant." []
is_a: CHEBI:25212 ! metabolite
is_a: CHEBI:64909 ! poison

[Term]
id: CHEBI:27027
name: micronutrient
def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." []
is_a: CHEBI:33284 ! nutrient

[Term]
id: CHEBI:2704
name: anastrozole
def: "A 1,2,4-triazole compound having a 3,5-bis(2-cyano-2-propyl)benzyl group at the 1-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:38976 ! alkylbenzene
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50790 ! has role EC 1.14.14.14 (aromatase) inhibitor

[Term]
id: CHEBI:27081
name: transition element atom
def: "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." []
is_a: CHEBI:33521 ! metal atom

[Term]
id: CHEBI:27082
name: trehalose
def: "A disaccharide formed by a (1↔1)-glycosidic bond between two units of <small>D</small>-glucose." []
is_a: CHEBI:131401 ! hexopyranosyl hexopyranoside

[Term]
id: CHEBI:27084
name: trehalose phosphate
is_a: CHEBI:23843 ! disaccharide phosphate

[Term]
id: CHEBI:27086
name: tributylstannane
is_a: CHEBI:25717 ! organotin compound

[Term]
id: CHEBI:27090
name: triaziquone
def: "A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which three of the ring hydrogens are replaced by aziridin-1-yl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132124 ! 1,4-benzoquinones
is_a: CHEBI:22681 ! aziridines
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:27092
name: tricarboxylic acid trianion
is_a: CHEBI:35753 ! tricarboxylic acid anion
is_a: CHEBI:38717 ! carboxylic acid trianion

[Term]
id: CHEBI:27093
name: tricarboxylic acid
def: "An oxoacid containing three carboxy groups." []
is_a: CHEBI:33575 ! carboxylic acid
relationship: RO:0018034 CHEBI:35753 ! is protonated form of tricarboxylic acid anion

[Term]
id: CHEBI:27096
name: trichlorobenzene
def: "Any member of the class of chlorobenzenes carrying three chloro substituents at unspecified positions." []
is_a: CHEBI:23132 ! chlorobenzenes

[Term]
id: CHEBI:27102
name: trichlorophenol
def: "Any one of the six possible isomers of trichlorophenol." []
is_a: CHEBI:15258 ! trichlorophenols

[Term]
id: CHEBI:27114
name: trihydroxy-5beta-cholanic acid
is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid

[Term]
id: CHEBI:27115
name: trihydroxybenzoic acid
is_a: CHEBI:24676 ! hydroxybenzoic acid

[Term]
id: CHEBI:27116
name: trihydroxyflavone
def: "Any  hydroxyflavone carrying three hydroxy groups at unspecified positions." []
is_a: CHEBI:24698 ! hydroxyflavone

[Term]
id: CHEBI:27131
name: trimethylarsine oxide
is_a: CHEBI:35843 ! arsine oxides

[Term]
id: CHEBI:27134
name: trimethylxanthine
is_a: CHEBI:25348 ! methylxanthine

[Term]
id: CHEBI:27135
name: trinitrotoluene
is_a: CHEBI:25566 ! nitrotoluene

[Term]
id: CHEBI:27136
name: triol
def: "A chemical compound containing three hydroxy groups." []
is_a: CHEBI:26191 ! polyol

[Term]
id: CHEBI:27137
name: triose
def: "A monosaccharide containing three carbon atoms, which is important in respiration. Only two trioses occur naturally: the aldotriose glyceraldehyde and the ketotriose dihydroxyacetone." []
is_a: CHEBI:35381 ! monosaccharide

[Term]
id: CHEBI:27150
name: trisaccharide
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:27153
name: monoatomic trication
is_a: CHEBI:25430 ! monoatomic polycation
is_a: CHEBI:64712 ! trivalent inorganic cation

[Term]
id: CHEBI:27162
name: tryptamines
def: "Tryptamine and its substitution derivatives." []
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:27171
name: organic heterobicyclic compound
is_a: CHEBI:33672 ! heterobicyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:27177
name: L-tyrosine derivative
def: "A proteinogenic amino acid derivative resulting from reaction of <small>L</small>-tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>L</small>-tyrosine by a heteroatom." []
is_a: CHEBI:62761 ! tyrosine derivative
is_a: CHEBI:84144 ! L-phenylalanine derivative
relationship: RO:0018038 CHEBI:17895 ! has functional parent L-tyrosine

[Term]
id: CHEBI:27207
name: univalent carboacyl group
def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." []
is_a: CHEBI:37838 ! carboacyl group

[Term]
id: CHEBI:27208
name: unsaturated fatty acid
def: "Any fatty acid containing at least one C=C or C≡C bond." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:2580 ! is protonated form of unsaturated fatty acid anion

[Term]
id: CHEBI:27214
name: uranium atom
is_a: CHEBI:33320 ! actinoid atom

[Term]
id: CHEBI:27216
name: urate(2-)
is_a: CHEBI:25810 ! oxopurine
is_a: CHEBI:46818 ! urate anion
relationship: RO:0018033 CHEBI:30848 ! is deprotonated form of urate(1-)

[Term]
id: CHEBI:27226
name: uric acid
def: "An oxopurine that is the final oxidation product of purine metabolism." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25810 ! oxopurine
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:30848 ! is protonated form of urate(1-)

[Term]
id: CHEBI:27232
name: uridine 5'-phosphate
is_a: CHEBI:27237 ! uridine phosphate

[Term]
id: CHEBI:27237
name: uridine phosphate
is_a: CHEBI:25608 ! nucleoside phosphate
relationship: RO:0018038 CHEBI:27242 ! has functional parent uridines

[Term]
id: CHEBI:27242
name: uridines
is_a: CHEBI:39446 ! pyrimidine ribonucleosides
relationship: RO:0018038 CHEBI:17568 ! has functional parent uracil

[Term]
id: CHEBI:27266
name: valine
def: "A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the α-carbon is substituted by an isopropyl group." []
is_a: CHEBI:22918 ! branched-chain amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:30353 ! has part isopropyl group
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32860 ! is deprotonated form of valinium
relationship: RO:0018034 CHEBI:32859 ! is protonated form of valinate

[Term]
id: CHEBI:27267
name: valine derivative
def: "An amino acid derivative resulting from reaction of valine at the amino group or the carboxy group, or from the replacement of any hydrogen of valine  by a heteroatom. The definition normally excludes peptides containing valine  residues." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:27266 ! has functional parent valine

[Term]
id: CHEBI:27273
name: vanadic acid
is_a: CHEBI:35166 ! vanadium coordination entity
is_a: CHEBI:36265 ! transition element oxoacid
relationship: RO:0018034 CHEBI:35169 ! is protonated form of dihydrogenvanadate

[Term]
id: CHEBI:27275
name: vanadium molecular entity
is_a: CHEBI:33746 ! vanadium group molecular entity
relationship: BFO:0000051 CHEBI:27698 ! has part vanadium atom

[Term]
id: CHEBI:27283
name: very long-chain fatty acid
def: "A fatty acid which has a chain length greater than C<small><sub>22</sub></small>. Very long-chain fatty acids which have a chain length greater than C27 are also known as ultra-long-chain fatty acids." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:58950 ! is protonated form of very long-chain fatty acid anion

[Term]
id: CHEBI:27288
name: vinca alkaloid
def: "A group of indole-indoline dimers which are alkaloids obtained from the <em>Vinca</em> genus of plants, together with semi-synthetic and fully synthetic analogues." []
is_a: CHEBI:65323 ! monoterpenoid indole alkaloid

[Term]
id: CHEBI:27300
name: vitamin D
def: "Any member of a group of fat-soluble hydroxy seco-steroids that exhibit biological activity against vitamin D deficiency. Vitamin D  can be obtained from sun exposure, food and supplements and is biologically inactive and converted into the biologically active calcitriol via double hydroxylation in the body." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36853 ! hydroxy seco-steroid
relationship: RO:0000087 CHEBI:24020 ! has role fat-soluble vitamin (role)

[Term]
id: CHEBI:27306
name: vitamin B6
def: "Any member of the group of pyridines that exhibit biological activity against vitamin B<small><sub>6</sub></small> deficiency. Vitamin B<small><sub>6</sub></small> deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B<small><sub>6</sub></small> consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms)." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:75769 ! B vitamin

[Term]
id: CHEBI:27311
name: volatile oil component
def: "Any plant metabolite that is found naturally as a component of a volatile oil." []
is_a: CHEBI:76924 ! plant metabolite

[Term]
id: CHEBI:27314
name: water-soluble vitamin (role)
def: "Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine." []
is_a: CHEBI:33229 ! vitamin (role)

[Term]
id: CHEBI:27325
name: xanthophyll
def: "A subclass of carotenoids consisting of the oxygenated carotenes." []
is_a: CHEBI:23044 ! carotenoid

[Term]
id: CHEBI:27338
name: xylene
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:38975 ! methylbenzene

[Term]
id: CHEBI:27358
name: yohimban alkaloid
is_a: CHEBI:65323 ! monoterpenoid indole alkaloid

[Term]
id: CHEBI:27363
name: zinc atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33340 ! zinc group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:27364
name: zinc molecular entity
is_a: CHEBI:33673 ! zinc group molecular entity
relationship: BFO:0000051 CHEBI:27363 ! has part zinc atom

[Term]
id: CHEBI:27365
name: zinc ion
is_a: CHEBI:24867 ! monoatomic ion
is_a: CHEBI:37253 ! elemental zinc

[Term]
id: CHEBI:27369
name: zwitterion
def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." []
is_a: CHEBI:51151 ! dipolar compound

[Term]
id: CHEBI:27375
name: vincaleukoblastine
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:27288 ! vinca alkaloid
is_a: CHEBI:38163 ! organic heterotetracyclic compound
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:38482 ! indole alkaloid fundamental parent
is_a: CHEBI:47622 ! acetate ester
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:61951 ! has role microtubule-destabilising agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:27376
name: methanesulfonic acid
def: "An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl." []
synonym: "Methanesulfonic acid" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47901 ! alkanesulfonic acid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:25224 ! is protonated form of methanesulfonate

[Term]
id: CHEBI:27385
name: tetrachloromethane
def: "A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups." []
synonym: "Tetrachloromethane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23148 ! chloromethanes
is_a: CHEBI:39226 ! chlorocarbon
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:27405
name: streptidine
def: "An amino cyclitol that is <em>scyllo</em>-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:61689 ! amino cyclitol
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018033 CHEBI:184376 ! is deprotonated form of streptidine(2+)
relationship: RO:0018038 CHEBI:10642 ! has functional parent scyllo-inositol

[Term]
id: CHEBI:27417
name: p-xylene
def: "A xylene with methyl groups at positions 1 and 4." []
is_a: CHEBI:27338 ! xylene

[Term]
id: CHEBI:27432
name: alpha-linolenic acid
def: "A linolenic acid with <i>cis</i>-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect." []
is_a: CHEBI:25048 ! linolenic acid
is_a: CHEBI:25681 ! omega-3 fatty acid
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:32387 ! is protonated form of alpha-linolenate
relationship: RO:0018034 CHEBI:528881 ! is protonated form of (9Z,12Z,15Z)-octadeca-9,12,15-trienoate

[Term]
id: CHEBI:27452
name: styrene
def: "A vinylarene that is benzene carrying a vinyl group. It has been isolated from the benzoin resin produced by <em>Styrax</em> species." []
synonym: "Styrene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:26799 ! styrenes
is_a: CHEBI:51324 ! vinylarene
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:27454
name: 1-chloro-2,2-bis(4'-chlorophenyl)ethylene
def: "A chlorophenylethylene that is chloroethene in which the methylene hydrogens are replaced by 4-chlorophenyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23155 ! chlorophenylethylene
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:27455
name: trichloroacetate
def: "A monocarboxylic acid anion that results from the removal of a proton from the carboxylic acid group of trichloroacetic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:30956 ! is deprotonated form of trichloroacetic acid
relationship: RO:0018038 CHEBI:30089 ! has functional parent acetate

[Term]
id: CHEBI:27470
name: folic acid
def: "An <em>N</em>-acyl-amino acid that is a form of the water-soluble vitamin B<small><sub>9</sub></small>. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation." []
is_a: CHEBI:37445 ! folic acids
is_a: CHEBI:51569 ! N-acyl-amino acid
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:62501 ! is protonated form of folate(2-)
relationship: RO:0018038 CHEBI:38794 ! has functional parent pteroic acid

[Term]
id: CHEBI:27477
name: D-valine
def: "The <small>D</small>-enantiomer of valine." []
synonym: "D-Valine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:27266 ! valine
relationship: RO:0018033 CHEBI:32856 ! is deprotonated form of D-valinium
relationship: RO:0018034 CHEBI:32855 ! is protonated form of D-valinate
relationship: RO:0018036 CHEBI:74338 ! is tautomer of D-valine zwitterion
relationship: RO:0018039 CHEBI:16414 ! is enantiomer of L-valine

[Term]
id: CHEBI:27496
name: simazine
def: "A diamino-1,3,5-triazine that is <em>N</em>,<em>N</em>'-diethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6." []
is_a: CHEBI:38168 ! chloro-1,3,5-triazine
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:27500
name: 4-aminobenzenesulfonic acid
def: "An  aminobenzenesulfonic acid that is aniline sulfonated at the <em>para</em>-position." []
synonym: "4-Aminobenzenesulfonic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33557 ! aminobenzenesulfonic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:76206 ! has role xenobiotic metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:20313 ! is protonated form of 4-aminobenzenesulfonate

[Term]
id: CHEBI:27504
name: mitomycin C
is_a: CHEBI:25357 ! mitomycin
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018034 CHEBI:194095 ! is protonated form of mitomycin C(1-)

[Term]
id: CHEBI:27518
name: acetylene
synonym: "Acetylene" EXACT [KEGG_COMPOUND]
synonym: "Ethyne" EXACT [KEGG_COMPOUND]
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:22339 ! alkyne
is_a: CHEBI:73477 ! terminal acetylenic compound

[Term]
id: CHEBI:27532
name: L-cysteine thioether
def: "Any <small>L</small>-cysteine derivative obtained by conversion of the thiol group into a sulfide." []
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:47910 ! S-substituted L-cysteine

[Term]
id: CHEBI:27560
name: boron atom
synonym: "Boron" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:137980 ! metalloid atom
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33317 ! boron group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:27561
name: oxirane
def: "A  saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:38104 ! oxacycle
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:27563
name: arsenic atom
synonym: "Arsenic" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:137980 ! metalloid atom
is_a: CHEBI:33300 ! pnictogen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:27568
name: selenium atom
synonym: "Selenium" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33303 ! chalcogen
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36335 ! has role trypanocidal drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary

[Term]
id: CHEBI:27570
name: histidine
def: "An α-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1<em>H</em>-imidazol-4-yl group at position 3." []
synonym: "Histidine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:33856 ! aromatic amino acid
relationship: BFO:0000051 CHEBI:50338 ! has part 1H-imidazol-4-ylmethyl group
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018033 CHEBI:32531 ! is deprotonated form of histidinium(1+)
relationship: RO:0018034 CHEBI:32529 ! is protonated form of histidinate(1-)

[Term]
id: CHEBI:27573
name: silicon atom
synonym: "Silicon" EXACT [KEGG_COMPOUND]
is_a: CHEBI:137980 ! metalloid atom
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33306 ! carbon group element atom

[Term]
id: CHEBI:27577
name: phosphoramidate ester
def: "A phosphoric ester (phosphate) that has an NR<small><sub>2</sub></small> instead of an OH group." []
is_a: CHEBI:17102 ! phosphoramide
is_a: CHEBI:37734 ! phosphoric ester

[Term]
id: CHEBI:27584
name: aldosterone
def: "A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney." []
is_a: CHEBI:131565 ! steroid aldehyde
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:25354 ! mineralocorticoid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:36887 ! 18-oxo steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:64600 ! C21-steroid hormone
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:27594
name: carbon atom
synonym: "Carbon" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33306 ! carbon group element atom
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:27607
name: thymol
def: "A phenol that is a natural monoterpene derivative of cymene." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25409 ! monoterpenoid
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0018040 CHEBI:28768 ! has parent hydride p-cymene

[Term]
id: CHEBI:27612
name: hydantoin
is_a: CHEBI:24628 ! imidazolidine-2,4-dione

[Term]
id: CHEBI:27617
name: monensin A
def: "A spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by <em>Streptomyces cinnamonensis</em>. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle." []
is_a: CHEBI:26179 ! polyether antibiotic
is_a: CHEBI:48847 ! heterocyclic fatty acid
is_a: CHEBI:59780 ! cyclic hemiketal
is_a: CHEBI:72600 ! spiroketal
relationship: RO:0000087 CHEBI:24869 ! has role ionophore
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35818 ! has role coccidiostat

[Term]
id: CHEBI:2762
name: antimycin A
def: "A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by <em>Streptomyces</em> bacteria and has found commercial use as a fish poison." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:145556 ! macrodiolide
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:24079 ! formamides
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:167183 ! has role piscicide
relationship: RO:0000087 CHEBI:25355 ! has role mitochondrial respiratory-chain inhibitor
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:27632
name: acetophenone
def: "A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22187 ! acetophenones
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent
relationship: RO:0000087 CHEBI:75767 ! has role animal metabolite

[Term]
id: CHEBI:27638
name: cobalt atom
def: "A cobalt group element atom that has atomic number 27." []
synonym: "Cobalt" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33358 ! cobalt group element atom
is_a: CHEBI:88184 ! metal allergen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:27641
name: cycloheximide
def: "A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon  bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium <em>Streptomyces griseus</em>." []
is_a: CHEBI:35356 ! dicarboximide
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:48589 ! piperidones
is_a: CHEBI:49318 ! piperidine antibiotic
is_a: CHEBI:87114 ! antibiotic fungicide
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018038 CHEBI:5435 ! has functional parent piperidine-2,6-dione

[Term]
id: CHEBI:27642
name: methyl tert-butyl ether
def: "An ether having methyl and <em>tert</em>-butyl as the two alkyl components." []
synonym: "tert-Butyl methyl ether" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:62803 ! has role fuel additive

[Term]
id: CHEBI:27656
name: camptothecin
def: "A pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-<em>b</em>]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the <i>S</i> enantiomer)." []
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:26509 ! quinoline alkaloid
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:48626 ! pyranoindolizinoquinoline
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50276 ! has role EC 5.99.1.2 (DNA topoisomerase) inhibitor
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:27659
name: 2-oxo aldehyde
def: "Any aldehyde having an oxo substituent at the 2-position." []
is_a: CHEBI:24960 ! ketoaldehyde

[Term]
id: CHEBI:27666
name: actinomycin D
is_a: CHEBI:15369 ! actinomycin
is_a: CHEBI:35213 ! cyclodepsipeptide
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:27689
name: decanoate
def: "A fatty acid anion 10:0 that is the conjugate base of decanoic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:194240 ! omega-methyl-medium-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:78118 ! fatty acid anion 10:0
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30813 ! is deprotonated form of decanoic acid

[Term]
id: CHEBI:27698
name: vanadium atom
synonym: "Vanadium" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33347 ! vanadium group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:27726
name: 6-chloro-1,3,5-triazine-2,4-diamine
is_a: CHEBI:38168 ! chloro-1,3,5-triazine
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
relationship: RO:0018038 CHEBI:38071 ! has functional parent 1,3,5-triazine-2,4-diamine
relationship: RO:0018038 CHEBI:38074 ! has functional parent 2-chloro-1,3,5-triazine

[Term]
id: CHEBI:27732
name: caffeine
def: "A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee." []
is_a: CHEBI:25810 ! oxopurine
is_a: CHEBI:27134 ! trimethylxanthine
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35337 ! has role central nervous system stimulant
relationship: RO:0000087 CHEBI:35471 ! has role psychotropic drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35498 ! has role diuretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50218 ! has role EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50925 ! has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
relationship: RO:0000087 CHEBI:53121 ! has role adenosine A2A receptor antagonist
relationship: RO:0000087 CHEBI:60809 ! has role adjuvant
relationship: RO:0000087 CHEBI:64047 ! has role food additive
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:67114 ! has role ryanodine receptor agonist
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite

[Term]
id: CHEBI:27741
name: 3'-hydroxyflavonoid
def: "Any hydroxyflavone with a hydroxy substituent at position 3'." []
is_a: CHEBI:24698 ! hydroxyflavone

[Term]
id: CHEBI:27744
name: glyphosate
def: "A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS)." []
is_a: CHEBI:24373 ! glycine derivative
is_a: CHEBI:44976 ! phosphonic acid
relationship: RO:0000087 CHEBI:20569 ! has role EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0018034 CHEBI:133673 ! is protonated form of glyphosate(1-)

[Term]
id: CHEBI:27750
name: ethyl acetate
def: "The acetate ester formed between acetic acid and ethanol." []
synonym: "ETHYL ACETATE" EXACT [PDBeChem]
synonym: "Ethyl acetate" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77706 ! has role EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor

[Term]
id: CHEBI:27777
name: acetohydroxamic acid
def: "A member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22177 ! acetohydroxamic acids
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:50635 ! has role EC 3.5.1.5 (urease) inhibitor
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018036 CHEBI:49029 ! is tautomer of N-hydroxyacetimidic acid
relationship: RO:0018038 CHEBI:27856 ! has functional parent acetamide

[Term]
id: CHEBI:27780
name: detergent
def: "A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions." []
is_a: CHEBI:33232 ! application
is_a: CHEBI:35195 ! surfactant

[Term]
id: CHEBI:27789
name: 1,2-dichloroethane
def: "A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2." []
synonym: "1,2-DICHLOROETHANE" EXACT [PDBeChem]
synonym: "1,2-Dichloroethane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36016 ! chloroethanes
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent

[Term]
id: CHEBI:27798
name: nitrobenzene
def: "A nitroarene consisting of benzene carrying a single nitro substituent. An industrial chemical used widely in the production of aniline." []
synonym: "NITROBENZENE" EXACT [PDBeChem]
synonym: "Nitrobenzene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:48109 ! nitrobenzenes
is_a: CHEBI:51132 ! nitroarene

[Term]
id: CHEBI:27808
name: heroin
def: "A morphinane alkaloid that is morphine bearing two acetyl substituents on the O-3 and O-6 positions. As with other opioids, heroin is used as both an analgesic and a recreational drug. Frequent and regular administration is associated with tolerance and physical dependence, which may develop into addiction. Its use includes treatment for acute pain, such as in severe physical trauma, myocardial infarction, post-surgical pain, and chronic pain, including end-stage cancer and other terminal illnesses." []
is_a: CHEBI:25418 ! morphinane alkaloid
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0018038 CHEBI:17303 ! has functional parent morphine

[Term]
id: CHEBI:27810
name: resorcinol
def: "A  benzenediol that is benzene dihydroxylated at positions 1 and 3." []
is_a: CHEBI:139520 ! phenolic donor
is_a: CHEBI:17701 ! benzenediol
is_a: CHEBI:33572 ! resorcinols
relationship: RO:0000087 CHEBI:139492 ! has role sensitiser
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:91025 ! has role erythropoietin inhibitor

[Term]
id: CHEBI:27822
name: 2-aminobenzimidazole
def: "A member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22715 ! benzimidazoles
relationship: RO:0000087 CHEBI:83399 ! has role marine xenobiotic metabolite

[Term]
id: CHEBI:27827
name: paraoxon
def: "An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl." []
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:37558 ! aryl dialkyl phosphate
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:278547
name: sodium azide
def: "The sodium salt of hydrogen azide (hydrazoic acid)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38702 ! inorganic sodium salt
relationship: BFO:0000051 CHEBI:40910 ! has part azide anion
relationship: RO:0000087 CHEBI:25355 ! has role mitochondrial respiratory-chain inhibitor
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:63490 ! has role explosive

[Term]
id: CHEBI:27856
name: acetamide
def: "A member of the class of acetamides that results from the formal condensation of acetic acid with ammonia." []
synonym: "ACETAMIDE" EXACT [PDBeChem]
synonym: "Acetamide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:83628 ! N-acylammonia
relationship: RO:0018036 CHEBI:49028 ! is tautomer of acetimidic acid

[Term]
id: CHEBI:27864
name: 2,6-dichloro-4-nitroaniline
def: "A nitroaniline that is 4-nitroaniline in which the hydrogens at positions 2 and 6 are replaced by chlorines. An agricultural fungicide, it is not approved for use in the European Union." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:25550 ! nitroaniline
is_a: CHEBI:87034 ! aromatic fungicide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:27869
name: chloroacetic acid
def: "A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent." []
synonym: "Chloroacetic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16277 ! haloacetic acid
is_a: CHEBI:36685 ! chlorocarboxylic acid
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0018034 CHEBI:23123 ! is protonated form of chloroacetate

[Term]
id: CHEBI:27871
name: chloroacetaldehyde
def: "Acetaldehyde substituted at C-2 by chlorine." []
synonym: "Chloroacetaldehyde" EXACT [KEGG_COMPOUND]
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0018038 CHEBI:15343 ! has functional parent acetaldehyde

[Term]
id: CHEBI:27878
name: 2-naphthylamine
def: "A naphthylamine carrying the amino group at position 2." []
is_a: CHEBI:50448 ! naphthylamine
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:27881
name: resveratrol
def: "A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:33572 ! resorcinols
is_a: CHEBI:36027 ! stilbenol
relationship: RO:0000087 CHEBI:140922 ! has role glioma-associated oncogene inhibitor
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:26115 ! has role phytoalexin

[Term]
id: CHEBI:27897
name: tryptophan
def: "An α-amino acid that is alanine bearing an indol-3-yl substituent at position 3." []
synonym: "Tryptophan" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:33856 ! aromatic amino acid
is_a: CHEBI:38631 ! aminoalkylindole
relationship: BFO:0000051 CHEBI:50337 ! has part 1H-indol-3-ylmethyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32728 ! is deprotonated form of tryptophanium
relationship: RO:0018034 CHEBI:32727 ! is protonated form of tryptophanate
relationship: RO:0018036 CHEBI:64554 ! is tautomer of tryptophan zwitterion

[Term]
id: CHEBI:27899
name: cisplatin
def: "A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a <i>cis</i> planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:51214 ! diamminedichloroplatinum
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent
relationship: RO:0000087 CHEBI:50684 ! has role cross-linking reagent
relationship: RO:0000087 CHEBI:50909 ! has role nephrotoxic agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:27902
name: tetracycline
def: "A broad-spectrum polyketide antibiotic produced by the <em>Streptomyces genus</em> of actinobacteria." []
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:26895 ! tetracyclines
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35820 ! has role antiprotozoal drug
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug
relationship: RO:0018036 CHEBI:77932 ! is tautomer of tetracycline zwitterion

[Term]
id: CHEBI:27903
name: (2,4,5-trichlorophenoxy)acetic acid
def: "A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2, 4 and 5 are substituted by chlorines." []
is_a: CHEBI:23152 ! chlorophenoxyacetic acid
is_a: CHEBI:27096 ! trichlorobenzene
relationship: RO:0000087 CHEBI:23582 ! has role defoliant
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0018034 CHEBI:19331 ! is protonated form of (2,4,5-trichlorophenoxy)acetate

[Term]
id: CHEBI:27909
name: paraldehyde
def: "A trioxane that is 1,3,5-trioxane substituted by methyl groups at positions 2, 4 and 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38044 ! trioxane
relationship: RO:0000087 CHEBI:35717 ! has role sedative

[Term]
id: CHEBI:27911
name: N(8)-acetylspermidine
def: "An acetylspermidine that is 1,8-diamino-4-azaoctane in which one of the hydrogens of the amino group attached to <em>C</em>-8 is replaced by an acetyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22204 ! acetylspermidine
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:58535 ! is deprotonated form of N(8)-acetylspermidinium(2+)

[Term]
id: CHEBI:27924
name: phenylhydrazine
def: "A phenylhydrazine that is the monophenyl derivative of hydrazine." []
synonym: "Phenylhydrazine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25996 ! phenylhydrazines
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic

[Term]
id: CHEBI:27928
name: parathion
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018038 CHEBI:16836 ! has functional parent 4-nitrophenol

[Term]
id: CHEBI:27933
name: beta-lactam antibiotic
def: "An organonitrogen heterocyclic antibiotic that contains a β-lactam ring." []
is_a: CHEBI:25558 ! organonitrogen heterocyclic antibiotic
is_a: CHEBI:35627 ! beta-lactam

[Term]
id: CHEBI:27941
name: pullulan
is_a: CHEBI:26384 ! pullulans
is_a: CHEBI:72813 ! exopolysaccharide

[Term]
id: CHEBI:27958
name: cocaine
def: "A tropane alkaloid obtained from leaves of the South American shrub <em>Erythroxylon coca</em>." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:36054 ! benzoate ester
is_a: CHEBI:37332 ! tropane alkaloid
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35337 ! has role central nervous system stimulant
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:36333 ! has role local anaesthetic
relationship: RO:0000087 CHEBI:38633 ! has role sodium channel blocker
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:51039 ! has role dopamine uptake inhibitor
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:60056 ! is deprotonated form of cocaine(1+)

[Term]
id: CHEBI:27975
name: L-glyceraldehyde
def: "The <small>L</small>-enantiomer of glyceraldehyde." []
is_a: CHEBI:5445 ! glyceraldehyde
relationship: RO:0018039 CHEBI:17378 ! is enantiomer of D-glyceraldehyde

[Term]
id: CHEBI:27977
name: erythronolide B
is_a: CHEBI:23955 ! erythronolide

[Term]
id: CHEBI:27991
name: benzonitrile
def: "A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group." []
synonym: "Benzonitrile" EXACT [KEGG_COMPOUND]
synonym: "Phenyl cyanide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:22712 ! benzenes

[Term]
id: CHEBI:27998
name: tungsten
synonym: "Tungsten" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33350 ! chromium group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:28001
name: vancomycin
def: "A complex glycopeptide from <em>Streptomyces orientalis</em>. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria <em>Staphylococcus aureus</em> and <em>Clostridium difficile</em>." []
is_a: CHEBI:24396 ! glycopeptide
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:76842 ! is deprotonated form of vancomycin(1+)
relationship: RO:0018038 CHEBI:47724 ! has functional parent vancomycin aglycone

[Term]
id: CHEBI:28017
name: starch
def: "The most important reserve polysaccharide found in plants. It is a glucan consisting of amylose and amylopectin." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37163 ! glucan
relationship: BFO:0000051 CHEBI:28057 ! has part amylopectin
relationship: BFO:0000051 CHEBI:28102 ! has part amylose
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:28024
name: cyanic acid
is_a: CHEBI:23423 ! pseudohalogen oxoacid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018034 CHEBI:29195 ! is protonated form of cyanate
relationship: RO:0018036 CHEBI:29202 ! is tautomer of isocyanic acid

[Term]
id: CHEBI:28044
name: phenylalanine
def: "An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group." []
synonym: "Phenylalanine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:33856 ! aromatic amino acid
relationship: BFO:0000051 CHEBI:22744 ! has part benzyl group
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:32505 ! is deprotonated form of phenylalaninium
relationship: RO:0018034 CHEBI:32504 ! is protonated form of phenylalaninate

[Term]
id: CHEBI:28054
name: o-cresol
def: "A cresol that is phenol substituted by a methyl group at position 2. It is a minor urinary metabolite of toluene." []
is_a: CHEBI:25399 ! cresol
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite

[Term]
id: CHEBI:28057
name: amylopectin
def: "A polydisperse highly branched polysaccharide derivative composed of chains of <small>D</small>-glucopyranose residues in α(1→4) glycosidic linkage. The chains are joined together by α(1→6) glycosidic linkages. A small number of α(1→3) glycosidic linkages and some 6-phosphate ester groups also may occur. The branches in amylopectin typically contain 24 to 30 glucose residues." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:65212 ! polysaccharide derivative
relationship: RO:0000087 CHEBI:76916 ! has role hyperglycemic agent

[Term]
id: CHEBI:28063
name: o-xylene
def: "A xylene substituted by methyl groups at positions 1 and 2." []
is_a: CHEBI:27338 ! xylene

[Term]
id: CHEBI:28073
name: chromium atom
def: "A chromium group element atom that has atomic number 24." []
synonym: "Chromium" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33350 ! chromium group element atom
is_a: CHEBI:88184 ! metal allergen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:28077
name: rifampicin
def: "A member of the class of rifamycins that is a a semisynthetic antibiotic derived from <em>Amycolatopsis rifamycinica</em> (previously known as <em>Amycolatopsis mediterranei</em> and <em>Streptomyces mediterranei</em>)." []
is_a: CHEBI:26580 ! rifamycins
is_a: CHEBI:38532 ! hydrazone
is_a: CHEBI:46847 ! N-iminopiperazine
is_a: CHEBI:46920 ! N-methylpiperazine
is_a: CHEBI:59779 ! cyclic ketal
is_a: CHEBI:72588 ! semisynthetic derivative
relationship: RO:0000087 CHEBI:171664 ! has role antiamoebic agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35816 ! has role leprostatic drug
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:37416 ! has role EC 2.7.7.6 (RNA polymerase) inhibitor
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77318 ! has role pregnane X receptor agonist
relationship: RO:0018036 CHEBI:71365 ! is tautomer of rifampicin zwitterion

[Term]
id: CHEBI:28078
name: 4-chlorophenol
def: "A monochlorophenol substituted at the <em>pare</em> position by a chlorine atom." []
synonym: "4-Chlorophenol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:38857 ! monochlorophenol

[Term]
id: CHEBI:28088
name: genistein
def: "A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:55465 ! 7-hydroxyisoflavones
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76989 ! has role phytoestrogen
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018034 CHEBI:74224 ! is protonated form of genistein(1-)

[Term]
id: CHEBI:28097
name: chlorobenzene
def: "The simplest member of the class of monochlorobenzenes, that is benzene in which a single hydrogen has been substituted by a chlorine." []
synonym: "Chlorobenzene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:46787 ! has role solvent

[Term]
id: CHEBI:28098
name: kanamycin B
is_a: CHEBI:24951 ! kanamycins
is_a: CHEBI:61689 ! amino cyclitol
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0018033 CHEBI:58549 ! is deprotonated form of kanamycin B(5+)

[Term]
id: CHEBI:28102
name: amylose
def: "A glucan composed of unbranched chains of <small>D</small>-glucopyranose residues in α(1→4) glycosidic linkage. The number of repeated glucose subunits (n) is usually in the range of 300 to 3000, but can be many thousands. One of the two components of starch (the other, 70-80%, being amylopectin). Cf. linear maltodextrin, in which the chain length is typically between 3 and 17 glucose units." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37163 ! glucan
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:28112
name: nickel atom
def: "Chemical element (nickel group element atom) with atomic number 28." []
is_a: CHEBI:33362 ! nickel group element atom
is_a: CHEBI:88184 ! metal allergen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:53000 ! has role epitope

[Term]
id: CHEBI:28119
name: 2,3,7,8-tetrachlorodibenzodioxine
is_a: CHEBI:36682 ! polychlorinated dibenzodioxine

[Term]
id: CHEBI:28123
name: diethanolamine
def: "A member of the class of ethanolamines that is ethanolamine having a <em>N</em>-hydroxyethyl substituent." []
is_a: CHEBI:23981 ! ethanolamines
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018038 CHEBI:16000 ! has functional parent ethanolamine

[Term]
id: CHEBI:28124
name: 4,4'-methylene-bis-(2-chloroaniline)
def: "A chloroaniline that consists of two 2-chloroaniline units joined by a methylene bridge." []
is_a: CHEBI:23130 ! chloroaniline
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:28125
name: all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
def: "A docosahexaenoic acid having six <i>cis</i>-double bonds at positions 4, 7, 10, 13, 16 and 19." []
synonym: "Docosahexaenoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25681 ! omega-3 fatty acid
is_a: CHEBI:36005 ! docosahexaenoic acid
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:83146 ! has role Daphnia tenebrosa metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:77016 ! is protonated form of (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate

[Term]
id: CHEBI:28143
name: digitalin
is_a: CHEBI:38092 ! cardenolide glycoside
relationship: RO:0018038 CHEBI:38105 ! has functional parent gitoxigenin

[Term]
id: CHEBI:28145
name: dibenzofuran
def: "A mancude organic heterotricyclic parent that consists of a furan ring flanked by two benzene rings <em>ortho</em>-fused across the 2,3- and 4,5-positions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36416 ! mancude organic heterotricyclic parent
is_a: CHEBI:38180 ! polycyclic heteroarene
is_a: CHEBI:38922 ! dibenzofurans
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic

[Term]
id: CHEBI:28159
name: D-asparagine
def: "An optically active form of asparagine having <small>D</small>-configuration." []
synonym: "D-Asparagine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:22653 ! asparagine
relationship: RO:0018033 CHEBI:32657 ! is deprotonated form of D-asparaginium
relationship: RO:0018034 CHEBI:32656 ! is protonated form of D-asparaginate
relationship: RO:0018036 CHEBI:74337 ! is tautomer of D-asparagine zwitterion
relationship: RO:0018039 CHEBI:17196 ! is enantiomer of L-asparagine

[Term]
id: CHEBI:28179
name: benzamide
def: "An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides." []
synonym: "Benzamide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22702 ! benzamides

[Term]
id: CHEBI:28196
name: erythromycin B
def: "An erythromycin that consists of erythronolide B having 2,6-dideoxy-3-<em>C</em>-methyl-3-<em>O</em>-methyl-α-<small>L</small>-<i>ribo</i>-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-<i>xylo</i>-hexopyranosyl residues attahced at positions 4 and 6 respectively." []
is_a: CHEBI:28963 ! amino sugar
is_a: CHEBI:48923 ! erythromycin
relationship: RO:0018038 CHEBI:27977 ! has functional parent erythronolide B

[Term]
id: CHEBI:28197
name: daidzein
def: "A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4'." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:55465 ! 7-hydroxyisoflavones
relationship: RO:0000087 CHEBI:131699 ! has role EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:67239 ! has role EC 3.2.1.20 (alpha-glucosidase) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76989 ! has role phytoestrogen
relationship: RO:0018034 CHEBI:77764 ! is protonated form of daidzein(1-)

[Term]
id: CHEBI:28200
name: 2-chloroethanol
def: "A chloroethanol carrying a chloro substituent at position 2." []
synonym: "2-Chloroethanol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23141 ! chloroethanol
relationship: RO:0000087 CHEBI:76206 ! has role xenobiotic metabolite

[Term]
id: CHEBI:28201
name: rotenone
def: "A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-<em>b</em>]furo[2,3-<em>h</em>]chromen-6(6a<em>H</em>)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2<i>R</i>,6a<i>S</i>,12a<i>S</i>-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of <em>Derris elliptica</em>)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:72581 ! rotenones
relationship: RO:0000087 CHEBI:167183 ! has role piscicide
relationship: RO:0000087 CHEBI:22917 ! has role phytogenic insecticide
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38498 ! has role mitochondrial NADH:ubiquinone reductase inhibitor

[Term]
id: CHEBI:28217
name: acrylonitrile
def: "A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an ethenyl group." []
synonym: "Acrylonitrile" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:80291 ! aliphatic nitrile
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite

[Term]
id: CHEBI:28222
name: 1,2,4-trichlorobenzene
def: "A trichlorobenzene with chloro substituents at positions 1, 2 and 4." []
synonym: "1,2,4-Trichlorobenzene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:27096 ! trichlorobenzene

[Term]
id: CHEBI:28225
name: D-leucine
def: "The <small>D</small>-enantiomer of leucine." []
synonym: "D-LEUCINE" EXACT [PDBeChem]
synonym: "D-Leucine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:25017 ! leucine
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:32624 ! is deprotonated form of D-leucinium
relationship: RO:0018034 CHEBI:32623 ! is protonated form of D-leucinate
relationship: RO:0018036 CHEBI:143079 ! is tautomer of D-leucine zwitterion
relationship: RO:0018039 CHEBI:15603 ! is enantiomer of L-leucine

[Term]
id: CHEBI:28230
name: hesperetin
def: "A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140332 ! 4'-methoxyflavanones
is_a: CHEBI:38738 ! monomethoxyflavanone
is_a: CHEBI:38739 ! trihydroxyflavanone
is_a: CHEBI:48024 ! 3'-hydroxyflavanones
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:61249 ! is protonated form of hesperetin(1-)

[Term]
id: CHEBI:28239
name: erythromycin E
is_a: CHEBI:48923 ! erythromycin
is_a: CHEBI:71989 ! ortho ester
relationship: RO:0018038 CHEBI:42355 ! has functional parent erythromycin A

[Term]
id: CHEBI:28240
name: dichloroacetate
def: "A monocarboxylic acid anion that is the conjugate base of dichloroacetic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0018033 CHEBI:36386 ! is deprotonated form of dichloroacetic acid
relationship: RO:0018038 CHEBI:30089 ! has functional parent acetate

[Term]
id: CHEBI:2825
name: aristolochic acid A
def: "An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all <em>Aristolochia</em> (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic." []
is_a: CHEBI:194147 ! aristolochic acids
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:25435 ! has role mutagen

[Term]
id: CHEBI:28260
name: galactose
def: "An aldohexose that is the C-4 epimer of glucose." []
synonym: "Galactose" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33917 ! aldohexose
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:28262
name: dimethyl sulfoxide
def: "A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents." []
synonym: "DIMETHYL SULFOXIDE" EXACT [PDBeChem]
synonym: "Dimethyl sulfoxide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:22063 ! sulfoxide
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:37335 ! has role MRI contrast agent
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:28266
name: fluorene
def: "An <em>ortho</em>-fused tricyclic hydrocarbon that is a major component of fossil fuels and their derivatives" []
synonym: "Fluorene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35296 ! ortho-fused polycyclic arene
is_a: CHEBI:37089 ! ortho-fused tricyclic hydrocarbon

[Term]
id: CHEBI:28300
name: glutamine
def: "An α-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4." []
synonym: "Glutamine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:50331 ! has part 3-amino-3-oxopropyl group
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32679 ! is deprotonated form of glutaminium
relationship: RO:0018034 CHEBI:32678 ! is protonated form of glutaminate

[Term]
id: CHEBI:28304
name: heparin
def: "A highly sulfated linear glycosaminoglycan comprising complex patterns of uronic acid-(1→4)-<small>D</small>-glucosamine repeating subunits. Used as an injectable anticoagulant, it has the highest negative charge density of any known biological molecule." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24505 ! heparins
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:28306
name: semicarbazide
def: "A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine." []
synonym: "Hydrazinecarboxamide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35363 ! carbohydrazide
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:64708 ! one-carbon compound

[Term]
id: CHEBI:28328
name: D-galactosamine
def: "The <small>D</small>-stereoisomer of galactosamine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24156 ! galactosamine
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:28331
name: erythromycin D
is_a: CHEBI:48923 ! erythromycin
relationship: RO:0018033 CHEBI:63677 ! is deprotonated form of erythromycin D(1+)
relationship: RO:0018038 CHEBI:27977 ! has functional parent erythronolide B

[Term]
id: CHEBI:28358
name: rac-lactic acid
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-lactic acid." []
synonym: "2-Hydroxypropanoic acid" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:42111 ! has part (R)-lactic acid
relationship: BFO:0000051 CHEBI:422 ! has part (S)-lactic acid
relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator
relationship: RO:0018034 CHEBI:24996 ! is protonated form of lactate

[Term]
id: CHEBI:28364
name: all-cis-5,8,11,14,17-icosapentaenoic acid
def: "An icosapentaenoic acid having five <i>cis</i>-double bonds at positions 5, 8, 11, 14 and 17." []
is_a: CHEBI:25681 ! omega-3 fatty acid
is_a: CHEBI:36006 ! icosapentaenoic acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:83038 ! has role Daphnia galeata metabolite
relationship: RO:0018034 CHEBI:58562 ! is protonated form of all-cis-5,8,11,14,17-icosapentaenoate

[Term]
id: CHEBI:28383
name: alpha,omega-dicarboxylic acid
is_a: CHEBI:35692 ! dicarboxylic acid

[Term]
id: CHEBI:28384
name: vitamin K
def: "Any member of a group of fat-soluble 2-methyl-1,4-napthoquinones that exhibit biological activity against vitamin K deficiency. Vitamin K is required for the synthesis of prothrombin and certain other blood coagulation factors." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132142 ! 1,4-naphthoquinones
relationship: RO:0000087 CHEBI:24020 ! has role fat-soluble vitamin (role)
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:28398
name: butan-2-one
def: "A dialkyl ketone that is a four-carbon ketone carrying a single keto- group at position <em>C</em>-2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:18044 ! dialkyl ketone
is_a: CHEBI:22951 ! butanone
is_a: CHEBI:51867 ! methyl ketone
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:28411
name: allicin
is_a: CHEBI:22063 ! sulfoxide
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:86494 ! botanical anti-fungal agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:28412
name: eriodictyol
def: "A tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3' and 4' respectively." []
is_a: CHEBI:38742 ! tetrahydroxyflavanone
is_a: CHEBI:48024 ! 3'-hydroxyflavanones

[Term]
id: CHEBI:28428
name: beta-hexachlorocyclohexane
def: "The β-isomer of hexachlorocyclohexane." []
is_a: CHEBI:24536 ! hexachlorocyclohexane
is_a: CHEBI:38656 ! organochlorine pesticide
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:28445
name: vincristine
def: "A vinca alkaloid with formula C<small><sub>46</sub></small>H<small><sub>56</sub></small>N<small><sub>4</sub></small>O<small><sub>10</sub></small> found in the Madagascar periwinkle, <em>Catharanthus roseus</em>. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer." []
synonym: "22-Oxovincaleukoblastine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24079 ! formamides
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:27288 ! vinca alkaloid
is_a: CHEBI:38163 ! organic heterotetracyclic compound
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:47622 ! acetate ester
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:61951 ! has role microtubule-destabilising agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:143658 ! is deprotonated form of vincristine(2+)
relationship: RO:0018040 CHEBI:27375 ! has parent hydride vincaleukoblastine

[Term]
id: CHEBI:28479
name: D-tyrosine
def: "An optically active form of tyrosine having <small>D</small>-configuration." []
synonym: "D-TYROSINE" EXACT [PDBeChem]
synonym: "D-Tyrosine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:18186 ! tyrosine
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:32775 ! is deprotonated form of D-tyrosinium
relationship: RO:0018034 CHEBI:32773 ! is protonated form of D-tyrosinate(1-)
relationship: RO:0018036 CHEBI:58570 ! is tautomer of D-tyrosine zwitterion
relationship: RO:0018039 CHEBI:17895 ! is enantiomer of L-tyrosine

[Term]
id: CHEBI:28484
name: isovaleric acid
def: "A C<small><sub>5</sub></small>, branched-chain saturated fatty acid." []
synonym: "3-Methylbutanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:38653 ! methylbutyric acid
relationship: RO:0000087 CHEBI:75768 ! has role mammalian metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:48942 ! is protonated form of isovalerate

[Term]
id: CHEBI:28487
name: reserpine
def: "An alkaloid found in the roots of <em>Rauwolfia serpentina</em> and <em>R. vomitoria</em>." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:27358 ! yohimban alkaloid
is_a: CHEBI:38481 ! alkaloid ester
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:65190 ! has role first generation antipsychotic
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:46690 ! has functional parent reserpic acid

[Term]
id: CHEBI:28488
name: m-xylene
def: "A xylene carrying methyl groups at positions 1 and 3." []
synonym: "1,3-Xylene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:27338 ! xylene

[Term]
id: CHEBI:28498
name: acadesine
def: "A 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is  is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22512 ! aminoimidazole
is_a: CHEBI:26556 ! 1-ribosylimidazolecarboxamide
is_a: CHEBI:60783 ! nucleoside analogue
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor

[Term]
id: CHEBI:28509
name: chloroethene
def: "A monohaloethene that is ethene in which one of the hydrogens has been replaced by a chloro group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:23142 ! chloroethenes
is_a: CHEBI:51313 ! monohaloethene
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:28520
name: 2,4,5-trichlorophenol
def: "A trichlorophenol carrying chloro groups at positions 2, 4 and 5." []
synonym: "2,4,5-Trichlorophenol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:27102 ! trichlorophenol

[Term]
id: CHEBI:28534
name: 1,2-dibromoethane
def: "A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae." []
synonym: "1,2-Dibromoethane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:22929 ! bromoalkane
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:39276 ! has role fumigant
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite

[Term]
id: CHEBI:28553
name: selenocystine
is_a: CHEBI:26629 ! selenoamino acid
is_a: CHEBI:47026 ! diselenide
relationship: RO:0018038 CHEBI:9093 ! has functional parent selenocysteine

[Term]
id: CHEBI:28579
name: epsilon-caprolactam
def: "A member of the class of caprolactams that is azepane substituted by an oxo group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23000 ! caprolactams
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite

[Term]
id: CHEBI:28591
name: guaiacol
def: "A  monomethoxybenzene that consists of phenol with a methoxy substituent at the <em>ortho</em> position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134251 ! guaiacols
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77035 ! has role expectorant
relationship: RO:0000087 CHEBI:77484 ! has role EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
relationship: RO:0018038 CHEBI:18135 ! has functional parent catechol

[Term]
id: CHEBI:28600
name: farnesol
def: "A farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:26199 ! polyprenol
is_a: CHEBI:36757 ! farnesane sesquiterpenoid
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite

[Term]
id: CHEBI:28616
name: carbamic acid
def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." []
synonym: "Carbamate" EXACT [KEGG_COMPOUND]
synonym: "CARBAMIC ACID" EXACT [PDBeChem]
synonym: "Carbamic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:35605 ! carbon oxoacid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:13941 ! is protonated form of carbamate

[Term]
id: CHEBI:28618
name: 1,4-dichlorobenzene
def: "A dichlorobenzene carrying chloro groups at positions 1 and 4." []
synonym: "1,4-Dichlorobenzene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23697 ! dichlorobenzene
relationship: RO:0000087 CHEBI:24852 ! has role insecticide

[Term]
id: CHEBI:28619
name: acrylamide
def: "A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140324 ! primary carboxamide
is_a: CHEBI:22216 ! acrylamides
is_a: CHEBI:83628 ! N-acylammonia
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:77523 ! has role Maillard reaction product
relationship: RO:0018038 CHEBI:18308 ! has functional parent acrylic acid

[Term]
id: CHEBI:28631
name: 3-phenylpropionic acid
def: "A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group." []
synonym: "3-Phenylpropanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:51057 ! is protonated form of 3-phenylpropionate
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:28640
name: lipoteichoic acid
def: "A teichoic acid which is covalently bound to a lipid." []
is_a: CHEBI:30049 ! teichoic acid

[Term]
id: CHEBI:28654
name: 3-methyl-2-oxovalerate
def: "A 2-oxo monocarboxylic acid anion that is the conjugate base of 3-methyl-2-oxovaleric acid, arising from deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:191201 ! branched-chain keto acid anion
is_a: CHEBI:35179 ! 2-oxo monocarboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:35932 ! is deprotonated form of 3-methyl-2-oxovaleric acid
relationship: RO:0018038 CHEBI:31011 ! has functional parent valerate

[Term]
id: CHEBI:28659
name: phosphorus atom
synonym: "Phosphorus" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33300 ! pnictogen
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient

[Term]
id: CHEBI:28675
name: dextrin
def: "Glucans produced by the hydrolysis of starch or glycogen. They are mixtures of polymers of <small>D</small>-glucose units linked by α(1→4) or α(1→6) glycosidic bonds." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37163 ! glucan
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:28680
name: cytarabine
def: "A pyrimidine nucleoside in which cytosine is attached to <small>D</small>-arabinofuranose via a β-<em>N</em><small><sup>1</small></sup>-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26440 ! pyrimidine nucleoside
is_a: CHEBI:38315 ! beta-D-arabinoside
is_a: CHEBI:63367 ! monosaccharide derivative
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:16040 ! has functional parent cytosine

[Term]
id: CHEBI:28683
name: kynurenine
def: "A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group." []
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:76224 ! aromatic ketone
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:67008 ! is protonated form of kynureninate

[Term]
id: CHEBI:28685
name: molybdenum atom
synonym: "Molybdenum" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33350 ! chromium group element atom
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient

[Term]
id: CHEBI:28689
name: dehydroepiandrosterone
def: "An androstanoid that is androst-5-ene substituted by a β-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands." []
synonym: "3beta-Hydroxyandrost-5-en-17-one" EXACT [KEGG_COMPOUND]
synonym: "3beta-hydroxyandrost-5-en-17-one" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:1722 ! 3beta-hydroxy-Delta(5)-steroid
is_a: CHEBI:19168 ! 17-oxo steroid
is_a: CHEBI:50402 ! androstanoid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50113 ! has role androgen
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:28694
name: copper atom
synonym: "Copper" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33366 ! copper group element atom
is_a: CHEBI:88184 ! metal allergen
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:28716
name: palmitoleic acid
def: "A hexadec-9-enoic acid in which the double bond at position C-9 has <em>cis</em> configuration." []
is_a: CHEBI:72004 ! hexadec-9-enoic acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:78444 ! has role EC 3.1.1.1 (carboxylesterase) inhibitor
relationship: RO:0000087 CHEBI:83038 ! has role Daphnia galeata metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018034 CHEBI:32372 ! is protonated form of palmitoleate

[Term]
id: CHEBI:28738
name: 2,6-dimethylaniline
def: "A primary arylamine that is aniline in which the hydrogens at the 2- and 6-positions are replaced by methyl groups. It is used in the production of some anasthetics and other chemicals. It is a drug metabolite of lidocaine (local anasthetic)." []
synonym: "2,6-Dimethylaniline" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23806 ! dimethylaniline
is_a: CHEBI:50471 ! primary arylamine
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:28741
name: sodium fluoride
def: "A metal fluoride salt with a Na(+) counterion." []
synonym: "Sodium fluoride" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24060 ! fluoride salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent

[Term]
id: CHEBI:28747
name: picolinic acid
def: "A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan." []
synonym: "PYRIDINE-2-CARBOXYLIC ACID" EXACT [PDBeChem]
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
relationship: RO:0000087 CHEBI:64345 ! has role MALDI matrix material
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:38184 ! is protonated form of picolinate

[Term]
id: CHEBI:28748
name: doxorubicin
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:25830 ! p-quinones
is_a: CHEBI:35315 ! deoxy hexoside
is_a: CHEBI:47779 ! aminoglycoside
is_a: CHEBI:49322 ! anthracycline antibiotic
is_a: CHEBI:51286 ! tetracenequinones
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:64816 ! is deprotonated form of doxorubicin(1+)
relationship: RO:0018038 CHEBI:165223 ! has functional parent Adriamycinone
relationship: RO:0018040 CHEBI:32600 ! has parent hydride tetracene

[Term]
id: CHEBI:28749
name: aryl beta-D-glucoside
is_a: CHEBI:22798 ! beta-D-glucoside
relationship: RO:0018038 CHEBI:33658 ! has functional parent arene

[Term]
id: CHEBI:28755
name: 2,4,6-trichlorophenol
def: "A trichlorophenol with phenolic substituents on positions 2, 4 and 6." []
synonym: "2,4,6-Trichlorophenol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27102 ! trichlorophenol
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018034 CHEBI:140426 ! is protonated form of 2,4,6-trichlorophenolate

[Term]
id: CHEBI:28757
name: fructose
def: "A ketohexose that is an isomer of glucose." []
synonym: "Fructose" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24973 ! ketohexose
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:28763
name: 4,4'-dichlorodiphenylmethane
def: "A chlorophenylmethane that is methane in which two of the hydrogens have been replaced by <em>p</em>-chlorophenyl groups." []
is_a: CHEBI:23156 ! chlorophenylmethane
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0018040 CHEBI:38884 ! has parent hydride diphenylmethane

[Term]
id: CHEBI:28768
name: p-cymene
def: "A monoterpene that is toluene substituted by an isopropyl group at position 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:35187 ! monoterpene
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite

[Term]
id: CHEBI:2877
name: aspartame
def: "A dipeptide obtained by formal condensation of the α-carboxy group of <small>L</small>-aspartic acid with the amino group of methyl <small>L</small>-phenylalaninate. Commonly used as an artificial sweetener." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:46761 ! dipeptide
relationship: RO:0000087 CHEBI:27027 ! has role micronutrient
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:63332 ! has role EC 3.1.3.1 (alkaline phosphatase) inhibitor
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018036 CHEBI:195544 ! is tautomer of aspartame zwitterion
relationship: RO:0018038 CHEBI:17053 ! has functional parent L-aspartic acid
relationship: RO:0018038 CHEBI:49339 ! has functional parent methyl L-phenylalaninate

[Term]
id: CHEBI:28775
name: hesperidin
def: "A disaccharide derivative that consists of hesperetin substituted by a 6-<em>O</em>-(α-<small>L</small>-rhamnopyranosyl)-β-<small>D</small>-glucopyranosyl moiety at position 7 via a glycosidic linkage." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140332 ! 4'-methoxyflavanones
is_a: CHEBI:26587 ! rutinoside
is_a: CHEBI:38738 ! monomethoxyflavanone
is_a: CHEBI:38749 ! dihydroxyflavanone
is_a: CHEBI:48024 ! 3'-hydroxyflavanones
is_a: CHEBI:63353 ! disaccharide derivative
is_a: CHEBI:72730 ! flavanone glycoside
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0018038 CHEBI:28230 ! has functional parent hesperetin

[Term]
id: CHEBI:28786
name: paraquat dichloride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36094 ! organic chloride salt
relationship: BFO:0000051 CHEBI:34905 ! has part paraquat
relationship: RO:0000087 CHEBI:26088 ! has role photosystem-I inhibitor

[Term]
id: CHEBI:28787
name: nitroglycerin
def: "A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25560 ! nitroglycerol
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50566 ! has role nitric oxide donor
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:51371 ! has role muscle relaxant
relationship: RO:0000087 CHEBI:63490 ! has role explosive
relationship: RO:0000087 CHEBI:66993 ! has role tocolytic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary

[Term]
id: CHEBI:28790
name: serotonin
def: "A primary amino compound that is the 5-hydroxy derivative of tryptamine." []
synonym: "3-(2-Aminoethyl)-1H-indol-5-ol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25375 ! monoamine molecular messenger
is_a: CHEBI:27162 ! tryptamines
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:84729 ! hydroxyindoles
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:350546 ! is deprotonated form of serotonin(1+)
relationship: RO:0018038 CHEBI:16765 ! has functional parent tryptamine

[Term]
id: CHEBI:28793
name: beta-D-glucan
is_a: CHEBI:37163 ! glucan

[Term]
id: CHEBI:28795
name: m-toluate
def: "A toluate that is the conjugate base of <em>m</em>-toluic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27021 ! toluate
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:10589 ! is deprotonated form of m-toluic acid

[Term]
id: CHEBI:28796
name: fructan
def: "Polysaccharides composed of fructose residues." []
synonym: "Fructan" EXACT [KEGG_COMPOUND]
is_a: CHEBI:37164 ! homopolysaccharide

[Term]
id: CHEBI:28798
name: rubber particle
def: "A polymer consisting of <i>cis</i>-linked prenyl units." []
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:53406 ! has part cis-1,4-polyisoprene

[Term]
id: CHEBI:28802
name: flavonols
def: "Any hydroxyflavone in which is the ring hydrogen at position 3 of the heterocyclic ring is replaced by a hydroxy group." []
is_a: CHEBI:24698 ! hydroxyflavone
relationship: RO:0018034 CHEBI:58588 ! is protonated form of flavonol oxoanion

[Term]
id: CHEBI:28805
name: cis-1,2-dichloroethene
is_a: CHEBI:18882 ! 1,2-dichloroethene

[Term]
id: CHEBI:28808
name: mannan
synonym: "Mannan" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37164 ! homopolysaccharide
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite

[Term]
id: CHEBI:28817
name: dodecane
def: "A straight-chain alkane with 12 carbon atoms. It has been isolated from the essential oils of various plants including <em>Zingiber officinale</em> (ginger)." []
synonym: "DODECANE" EXACT [PDBeChem]
synonym: "Dodecane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:28829
name: aminophenol
def: "A substituted aniline carrying a hydroxy substituent. A 'closed class'." []
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:28830
name: chlorambucil
def: "A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37598 ! nitrogen mustard
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:28831
name: propan-1-ol
def: "The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group." []
synonym: "Propan-1-ol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:157770 ! short-chain primary fatty alcohol
is_a: CHEBI:26191 ! polyol
is_a: CHEBI:26279 ! propan-1-ols
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent

[Term]
id: CHEBI:28834
name: deoxycholic acid
def: "A bile acid that is 5β-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively." []
is_a: CHEBI:131620 ! C24-steroid
is_a: CHEBI:23775 ! dihydroxy-5beta-cholanic acid
is_a: CHEBI:3098 ! bile acid
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018034 CHEBI:23614 ! is protonated form of deoxycholate

[Term]
id: CHEBI:28837
name: octanoic acid
def: "A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid." []
synonym: "Octanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:25646 ! is protonated form of octanoate

[Term]
id: CHEBI:28842
name: octadecanoic acid
def: "A C<small><sub>18</sub></small> straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and  plastics." []
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:25629 ! is protonated form of octadecanoate
relationship: RO:0018040 CHEBI:32926 ! has parent hydride octadecane

[Term]
id: CHEBI:28851
name: phenanthrene
def: "A polycyclic aromatic hydrocarbon composed of three fused benzene rings which takes its name from the two terms 'phenyl' and 'anthracene.'" []
synonym: "PHENANTHRENE" EXACT [PDBeChem]
synonym: "Phenanthrene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25961 ! phenanthrenes
is_a: CHEBI:35296 ! ortho-fused polycyclic arene
is_a: CHEBI:37089 ! ortho-fused tricyclic hydrocarbon
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:28854
name: 2,4-D
def: "A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines." []
is_a: CHEBI:23152 ! chlorophenoxyacetic acid
is_a: CHEBI:23697 ! dichlorobenzene
relationship: RO:0000087 CHEBI:23582 ! has role defoliant
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:77484 ! has role EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:19351 ! is protonated form of (2,4-dichlorophenoxy)acetate

[Term]
id: CHEBI:28859
name: 5alpha-androstane
def: "The 5α-stereoisomer of androstane." []
synonym: "5alpha-Androstane" EXACT [KEGG_COMPOUND]
synonym: "Androstane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35509 ! androstane
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:28863
name: flavanones
def: "Members of the class of flavans with a 3,4-dihydro-2-aryl-2<em>H</em>-1-benzopyran-4-one skeleton and its substituted derivatives." []
is_a: CHEBI:38672 ! flavans
is_a: CHEBI:3992 ! cyclic ketone

[Term]
id: CHEBI:28864
name: tobramycin
def: "A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22479 ! amino cyclitol glycoside
is_a: CHEBI:61689 ! amino cyclitol
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0018033 CHEBI:73678 ! is deprotonated form of tobramycin(5+)
relationship: RO:0018038 CHEBI:28098 ! has functional parent kanamycin B

[Term]
id: CHEBI:28865
name: taurocholic acid
def: "A bile acid taurine conjugate of  cholic acid that usually occurs as the sodium salt of bile in mammals." []
is_a: CHEBI:23219 ! bile acid taurine conjugate
is_a: CHEBI:37793 ! amino sulfonic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:36257 ! is protonated form of taurocholate
relationship: RO:0018038 CHEBI:16359 ! has functional parent cholic acid

[Term]
id: CHEBI:28866
name: tetracosanoic acid
def: "A C<small><sub>24</sub></small> straight-chain saturated fatty acid." []
synonym: "Tetracosanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:27283 ! very long-chain fatty acid
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83146 ! has role Daphnia tenebrosa metabolite
relationship: RO:0018034 CHEBI:31014 ! is protonated form of tetracosanoate

[Term]
id: CHEBI:28868
name: fatty acid anion
def: "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:35366 ! is deprotonated form of fatty acid

[Term]
id: CHEBI:28869
name: menadione
def: "A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia." []
is_a: CHEBI:28384 ! vitamin K
relationship: RO:0000087 CHEBI:147285 ! has role EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite

[Term]
id: CHEBI:28875
name: tetradecanoic acid
def: "A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat." []
synonym: "MYRISTIC ACID" EXACT [PDBeChem]
synonym: "Myristic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78444 ! has role EC 3.1.1.1 (carboxylesterase) inhibitor
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:30807 ! is protonated form of tetradecanoate

[Term]
id: CHEBI:28876
name: melphalan
def: "A phenylalanine derivative comprising <small>L</small>-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37598 ! nitrogen mustard
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
is_a: CHEBI:84144 ! L-phenylalanine derivative
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:28880
name: (S)-mevalonic acid
def: "The (<i>S</i>)-enantiomer of mevalonic acid." []
is_a: CHEBI:194519 ! 3,5-dihydroxy-3-methylpentanoic acid
relationship: RO:0018034 CHEBI:18790 ! is protonated form of (S)-mevalonate
relationship: RO:0018039 CHEBI:17710 ! is enantiomer of (R)-mevalonic acid

[Term]
id: CHEBI:28884
name: N-phenylacetamide
def: "A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a phenyl group." []
synonym: "N-Phenylacetamide" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13248 ! anilide
is_a: CHEBI:22160 ! acetamides
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:28885
name: butan-1-ol
def: "A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:157770 ! short-chain primary fatty alcohol
is_a: CHEBI:26191 ! polyol
is_a: CHEBI:50584 ! alkyl alcohol
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:28901
name: busulfan
def: "A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25223 ! methanesulfonate ester
is_a: CHEBI:33552 ! sulfonic acid derivative
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67105 ! has role insect sterilant
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:41189 ! has functional parent butane-1,4-diol

[Term]
id: CHEBI:28905
name: prop-2-yn-1-ol
def: "A terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1." []
synonym: "Prop-2-yn-1-ol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26313 ! propynol
is_a: CHEBI:73477 ! terminal acetylenic compound
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite

[Term]
id: CHEBI:28918
name: (R)-adrenaline
def: "The <i>R</i>-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response." []
is_a: CHEBI:194548 ! 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
relationship: RO:0000087 CHEBI:24621 ! has role hormone
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35569 ! has role alpha-adrenergic agonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:50513 ! has role mydriatic agent
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0018033 CHEBI:71406 ! is deprotonated form of (R)-adrenaline(1+)
relationship: RO:0018039 CHEBI:40751 ! is enantiomer of (S)-adrenaline

[Term]
id: CHEBI:28925
name: mechlorethamine
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37598 ! nitrogen mustard
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:28934
name: vitamin D2
def: "A vitamin D supplement and has been isolated from alfalfa." []
is_a: CHEBI:27300 ! vitamin D
is_a: CHEBI:36819 ! seco-ergostane
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:33288 ! has role rodenticide
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:28938
name: ammonium
def: "An onium cation obtained by protonation of ammonia." []
synonym: "ammonium" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35106 ! nitrogen hydride
is_a: CHEBI:50313 ! onium cation
is_a: CHEBI:60242 ! monovalent inorganic cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16134 ! is protonated form of ammonia

[Term]
id: CHEBI:28939
name: N-acetyl-L-cysteine
def: "An  <em>N</em>-acetyl-<small>L</small>-amino acid that is the <em>N</em>-acetylated derivative of the natural amino acid <small>L</small>-cysteine." []
synonym: "N-ACETYL-L-CYSTEINE" EXACT [PDBeChem]
is_a: CHEBI:21545 ! N-acetyl-L-amino acid
is_a: CHEBI:22198 ! acetylcysteine
is_a: CHEBI:83824 ! L-cysteine derivative
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74529 ! has role antidote to paracetamol poisoning
relationship: RO:0000087 CHEBI:77034 ! has role mucolytic
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:78236 ! is protonated form of N-acetyl-L-cysteinate

[Term]
id: CHEBI:28950
name: N-methyl-N-picrylnitramine
def: "A nitramine that is methylamine in which one of the hydrogens attached to the nitrogen is substituted by a nitro group while the other is substituted by a 2,4,6-trinitrophenyl group. A yellow crystalline powder, it is a high explosive, capable of being detonated by friction, shock, or a spark." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25543 ! nitramine
relationship: RO:0000087 CHEBI:63490 ! has role explosive

[Term]
id: CHEBI:28963
name: amino sugar
def: "Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups." []
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:28965
name: dicarboxylic acid dianion
def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion
is_a: CHEBI:38716 ! carboxylic acid dianion

[Term]
id: CHEBI:28971
name: ampicillin
def: "A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group." []
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:88187 ! penicillin allergen
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0018034 CHEBI:50658 ! is protonated form of ampicillin(1-)

[Term]
id: CHEBI:28973
name: strychnine
def: "A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position." []
is_a: CHEBI:52157 ! organic heteroheptacyclic compound
is_a: CHEBI:65323 ! monoterpenoid indole alkaloid
relationship: RO:0000087 CHEBI:33288 ! has role rodenticide
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:48873 ! has role cholinergic antagonist
relationship: RO:0000087 CHEBI:62754 ! has role glycine receptor antagonist
relationship: RO:0018033 CHEBI:90700 ! is deprotonated form of strychnine(1+)
relationship: RO:0018040 CHEBI:36337 ! has parent hydride strychnidine

[Term]
id: CHEBI:28976
name: carbonic acid
synonym: "Carbonic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35605 ! carbon oxoacid
is_a: CHEBI:36961 ! chalcocarbonic acid
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:17544 ! is protonated form of hydrogencarbonate

[Term]
id: CHEBI:28984
name: aluminium atom
synonym: "Aluminium" EXACT [KEGG_COMPOUND]
is_a: CHEBI:233500 ! post-transition metal atom
is_a: CHEBI:33317 ! boron group element atom

[Term]
id: CHEBI:29005
name: cyclohexane
def: "An alicyclic hydrocarbon comprising a ring of six carbon atoms; the cyclic form of hexane, used as a raw material in the manufacture of nylon." []
synonym: "CYCLOHEXANE" EXACT [PDBeChem]
synonym: "Cyclohexane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:23453 ! cycloalkane
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent

[Term]
id: CHEBI:29007
name: ceftriaxone
def: "A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups." []
is_a: CHEBI:23066 ! cephalosporin
is_a: CHEBI:36816 ! oxime O-ether
is_a: CHEBI:38418 ! 1,3-thiazoles
is_a: CHEBI:39410 ! 1,2,4-triazines
relationship: RO:0000087 CHEBI:35625 ! has role EC 3.5.2.6 (beta-lactamase) inhibitor
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0018034 CHEBI:53658 ! is protonated form of ceftriaxone(1-)

[Term]
id: CHEBI:29014
name: cordycepin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22260 ! adenosines
is_a: CHEBI:36987 ! 3'-deoxyribonucleoside
relationship: RO:0000087 CHEBI:25605 ! has role nucleoside antibiotic
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:29016
name: arginine
def: "An α-amino acid that is glycine in which the α-is substituted by a 3-guanidinopropyl group." []
synonym: "Arginine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:26167 ! polar amino acid
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:50340 ! has part 3-carbamimidamidopropyl group
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32696 ! is deprotonated form of argininium(1+)
relationship: RO:0018034 CHEBI:32695 ! is protonated form of argininate

[Term]
id: CHEBI:29019
name: nonanoic acid
def: "A C<small><sub>9</sub></small> straight-chain saturated fatty acid which occurs naturally as esters of the oil of pelargonium. Has antifungal properties, and is also used as a herbicide as well as in the preparation of plasticisers and lacquers." []
synonym: "Nonanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid
relationship: RO:0000087 CHEBI:22583 ! has role antifeedant
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:32361 ! is protonated form of nonanoate
relationship: RO:0018040 CHEBI:32892 ! has parent hydride nonane

[Term]
id: CHEBI:29021
name: hexane
def: "An unbranched alkane containing six carbon atoms." []
synonym: "HEXANE" EXACT [PDBeChem]
synonym: "Hexane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:29027
name: trans-1,2-dichloroethene
is_a: CHEBI:18882 ! 1,2-dichloroethene

[Term]
id: CHEBI:29032
name: (R)-pantothenate
def: "A pantothenate that is the conjugate base of (<i>R</i>)-pantothenic acid, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:16454 ! pantothenate
is_a: CHEBI:176840 ! vitamin B5
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:46905 ! is deprotonated form of (R)-pantothenic acid

[Term]
id: CHEBI:29033
name: iron(2+)
synonym: "Iron(2+)" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24875 ! iron cation
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:29034
name: iron(3+)
synonym: "Iron(3+)" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24875 ! iron cation
is_a: CHEBI:27153 ! monoatomic trication
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:29036
name: copper(2+)
def: "An ion of copper carrying a double positive charge." []
synonym: "copper(II) cation" EXACT [ChEBI]
is_a: CHEBI:23378 ! copper cation
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation

[Term]
id: CHEBI:2904
name: atenolol
def: "An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an <em>N</em>-isopropyl substituent." []
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35533 ! propanolamine
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:66991 ! has role sympatholytic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:29067
name: carboxylic acid anion
def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." []
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:35406 ! oxoanion
relationship: RO:0018033 CHEBI:33575 ! is deprotonated form of carboxylic acid

[Term]
id: CHEBI:29069
name: phthalic acid
def: "A benzenedicarboxylic acid cosisting of two carboxy groups at <em>ortho</em> positions." []
is_a: CHEBI:26094 ! benzenedicarboxylic acid
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:30800 ! is protonated form of phthalate(1-)

[Term]
id: CHEBI:29073
name: L-ascorbic acid
def: "The <small>L</small>-enantiomer of ascorbic acid and conjugate acid of <small>L</small>-ascorbate." []
is_a: CHEBI:176783 ! vitamin C
is_a: CHEBI:22652 ! ascorbic acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:23354 ! has role coenzyme
relationship: RO:0000087 CHEBI:64577 ! has role flour treatment agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77962 ! has role food antioxidant
relationship: RO:0000087 CHEBI:78006 ! has role food colour retention agent
relationship: RO:0000087 CHEBI:85046 ! has role skin lightening agent
relationship: RO:0018034 CHEBI:38290 ! is protonated form of L-ascorbate
relationship: RO:0018039 CHEBI:51384 ! is enantiomer of D-ascorbic acid

[Term]
id: CHEBI:29075
name: mononucleotide
is_a: CHEBI:36976 ! nucleotide

[Term]
id: CHEBI:29084
name: (2->1)-beta-D-fructan
def: "A fructan in which the <small>D</small>-fructose building blocks are connected by β-(2→1) linkages." []
is_a: CHEBI:28796 ! fructan

[Term]
id: CHEBI:29101
name: sodium(1+)
def: "A monoatomic monocation obtained from sodium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25414 ! monoatomic monocation
is_a: CHEBI:33504 ! alkali metal cation
is_a: CHEBI:37246 ! elemental sodium
is_a: CHEBI:60242 ! monovalent inorganic cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:29103
name: potassium(1+)
def: "A monoatomic monocation obtained from potassium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25414 ! monoatomic monocation
is_a: CHEBI:33504 ! alkali metal cation
is_a: CHEBI:37247 ! elemental potassium
is_a: CHEBI:60242 ! monovalent inorganic cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:29105
name: zinc(2+)
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation
is_a: CHEBI:63056 ! zinc cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:29108
name: calcium(2+)
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:39123 ! calcium cation
is_a: CHEBI:60240 ! divalent metal cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:2911
name: atorvastatin calcium trihydrate
def: "A hydrate that is the trihydrate form of atorvastatin calcium." []
is_a: CHEBI:35505 ! hydrate
is_a: CHEBI:87635 ! statin (synthetic)
relationship: BFO:0000051 CHEBI:50686 ! has part atorvastatin calcium
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:29125
name: arsenate(3-)
def: "An arsenate ion resulting from the removal of three protons from arsenic acid." []
synonym: "Arsenate" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22629 ! arsenate ion
relationship: RO:0018033 CHEBI:48597 ! is deprotonated form of arsenate(2-)

[Term]
id: CHEBI:29133
name: dextrorphan
is_a: CHEBI:25418 ! morphinane alkaloid

[Term]
id: CHEBI:29192
name: hydrogenperoxide(1-)
is_a: CHEBI:33693 ! oxygen hydride
relationship: RO:0018033 CHEBI:16240 ! is deprotonated form of hydrogen peroxide

[Term]
id: CHEBI:29195
name: cyanate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36828 ! pseudohalide anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28024 ! is deprotonated form of cyanic acid
relationship: RO:0018033 CHEBI:29202 ! is deprotonated form of isocyanic acid

[Term]
id: CHEBI:29200
name: thiocyanic acid
def: "A hydracid that is cyanic acid in which the oxygen is replaced by a sulfur atom." []
synonym: "Thiocyanic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:33405 ! hydracid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:18022 ! is protonated form of thiocyanate
relationship: RO:0018036 CHEBI:24928 ! is tautomer of isothiocyanic acid

[Term]
id: CHEBI:29202
name: isocyanic acid
def: "A colourless, volatile, poisonous inorganic compound with the formula HNCO; the simplest stable chemical compound that contains carbon, hydrogen, nitrogen, and oxygen, the four most commonly-found elements in organic chemistry and biology." []
is_a: CHEBI:33405 ! hydracid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018034 CHEBI:29195 ! is protonated form of cyanate
relationship: RO:0018036 CHEBI:28024 ! is tautomer of cyanic acid

[Term]
id: CHEBI:29213
name: sulfinic acid
is_a: CHEBI:33402 ! sulfur oxoacid
relationship: RO:0018034 CHEBI:9341 ! is protonated form of sulfinate

[Term]
id: CHEBI:29214
name: sulfonic acid
is_a: CHEBI:33402 ! sulfur oxoacid
relationship: RO:0018034 CHEBI:33543 ! is protonated form of sulfonate
relationship: RO:0018036 CHEBI:48854 ! is tautomer of sulfurous acid

[Term]
id: CHEBI:29219
name: chlorous acid
is_a: CHEBI:33426 ! chlorine oxoacid
relationship: RO:0018034 CHEBI:17441 ! is protonated form of chlorite

[Term]
id: CHEBI:2922
name: auranofin
def: "An <em>S</em>-glycosyl compound consisting of 2,3,4,6-tetra-<em>O</em>-acetyl-1-thio-β-<small>D</small>-glucopyranose with the sufur atom coordinated to (triethylphosphoranylidene)gold. It is administered orally for the treatment of active progressive rheumatoid arthritis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33971 ! gold coordination entity
is_a: CHEBI:35275 ! S-glycosyl compound
relationship: RO:0000087 CHEBI:171664 ! has role antiamoebic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:64670 ! has role EC 1.8.1.9 (thioredoxin reductase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:29221
name: perchloric acid
is_a: CHEBI:33426 ! chlorine oxoacid
relationship: RO:0018034 CHEBI:49706 ! is protonated form of perchlorate

[Term]
id: CHEBI:29222
name: hypochlorite
is_a: CHEBI:33437 ! chlorine oxoanion
is_a: CHEBI:37750 ! chlorine oxide
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:24757 ! is deprotonated form of hypochlorous acid

[Term]
id: CHEBI:29223
name: bromate
is_a: CHEBI:33444 ! bromine oxoanion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:49382 ! is deprotonated form of bromic acid

[Term]
id: CHEBI:29228
name: hydrogen fluoride
def: "A diatomic molecule containing covalently bonded hydrogen and fluorine atoms." []
is_a: CHEBI:18140 ! hydrogen halide
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0018033 CHEBI:50314 ! is deprotonated form of fluoronium
relationship: RO:0018034 CHEBI:17051 ! is protonated form of fluoride

[Term]
id: CHEBI:29233
name: deuteron
def: "Nucleus of the <small><sup>2</small></sup>H atom." []
is_a: CHEBI:15378 ! hydron

[Term]
id: CHEBI:29237
name: deuterium atom
def: "The stable isotope of hydrogen with relative atomic mass 2.014102 and a natural abundance of 0.0115 atom percent (from Greek δευτερον, second)." []
is_a: CHEBI:49637 ! hydrogen atom
relationship: BFO:0000051 CHEBI:29233 ! has part deuteron

[Term]
id: CHEBI:29242
name: arsenite(1-)
def: "An arsenite ion resulting from the removal of a proton from one of the hydroxy groups of arsenous acid." []
is_a: CHEBI:22633 ! arsenite ion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:49900 ! is deprotonated form of arsenous acid
relationship: RO:0018034 CHEBI:29243 ! is protonated form of arsenite(2-)

[Term]
id: CHEBI:29243
name: arsenite(2-)
def: "An arsenite ion resulting from the removal of a proton from two of the hydroxy groups of arsenous acid." []
is_a: CHEBI:22633 ! arsenite ion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:29242 ! is deprotonated form of arsenite(1-)
relationship: RO:0018034 CHEBI:29866 ! is protonated form of arsenite(3-)

[Term]
id: CHEBI:29256
name: thiol
def: "An organosulfur compound in which a thiol group, ‒SH, is attached to a carbon atom of any aliphatic or aromatic moiety." []
synonym: "Thiol" EXACT [KEGG_COMPOUND]
synonym: "thiols" EXACT [ChEBI]
is_a: CHEBI:33261 ! organosulfur compound
relationship: BFO:0000051 CHEBI:29917 ! has part thiol group

[Term]
id: CHEBI:29258
name: dihydrogenphosphite
def: "A monovalent inorganic anion obtained by deprotonation of phosphorous acid." []
is_a: CHEBI:26045 ! phosphite ion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:36361 ! is deprotonated form of phosphorous acid
relationship: RO:0018034 CHEBI:29259 ! is protonated form of hydrogenphosphite

[Term]
id: CHEBI:29259
name: hydrogenphosphite
def: "A divalent inorganic anion resulting from the removal of a proton from two of the hydroxy groups of phosphorous acid." []
is_a: CHEBI:26045 ! phosphite ion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:29258 ! is deprotonated form of dihydrogenphosphite
relationship: RO:0018034 CHEBI:45064 ! is protonated form of phosphite(3-)

[Term]
id: CHEBI:29277
name: dinitride(2-)
is_a: CHEBI:33266 ! diatomic nitrogen
relationship: RO:0018033 CHEBI:30103 ! is deprotonated form of diazenide

[Term]
id: CHEBI:29278
name: dinitride(4-)
is_a: CHEBI:33266 ! diatomic nitrogen
relationship: RO:0018033 CHEBI:30104 ! is deprotonated form of diazanetriide

[Term]
id: CHEBI:29281
name: alkyl sulfate
is_a: CHEBI:25704 ! organic sulfate
is_a: CHEBI:26819 ! sulfuric ester
relationship: RO:0018034 CHEBI:83414 ! is protonated form of alkyl sulfate(1-)

[Term]
id: CHEBI:29287
name: gold atom
is_a: CHEBI:33366 ! copper group element atom

[Term]
id: CHEBI:29290
name: thionyl chloride
def: "A sulfinyl halide in which both of the halide atoms are chorines." []
is_a: CHEBI:23117 ! chlorine molecular entity
is_a: CHEBI:50096 ! sulfinyl halide

[Term]
id: CHEBI:29308
name: oxalonitrile
def: "A dinitrile that is ethane substituted by two cyano groups." []
is_a: CHEBI:36867 ! pseudohalogen
is_a: CHEBI:51308 ! dinitrile

[Term]
id: CHEBI:29317
name: selanide
is_a: CHEBI:36903 ! selenium hydride
relationship: RO:0018033 CHEBI:16503 ! is deprotonated form of selane

[Term]
id: CHEBI:29321
name: sodium nitroprusside
def: "An organic sodium salt that is the disodium salt of nitroprusside." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: BFO:0000051 CHEBI:7596 ! has part nitroprusside
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50566 ! has role nitric oxide donor
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:29337
name: azanide
is_a: CHEBI:35106 ! nitrogen hydride
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:16134 ! is deprotonated form of ammonia
relationship: RO:0018034 CHEBI:29340 ! is protonated form of hydridonitrate(2-)

[Term]
id: CHEBI:29340
name: hydridonitrate(2-)
def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." []
is_a: CHEBI:35106 ! nitrogen hydride
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:29337 ! is deprotonated form of azanide

[Term]
id: CHEBI:29347
name: monocarboxylic acid amide
def: "A carboxamide derived from a monocarboxylic acid." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:29348
name: fatty amide
def: "A monocarboxylic acid amide derived from a fatty acid." []
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:61697 ! fatty acid derivative
relationship: RO:0018034 CHEBI:229684 ! is protonated form of fatty amide anion

[Term]
id: CHEBI:29360
name: methanediide
is_a: CHEBI:38222 ! hydrocarbyl anion
relationship: RO:0018033 CHEBI:29438 ! is deprotonated form of methanide

[Term]
id: CHEBI:29365
name: phosgene
def: "An acyl chloride obtained by substitution of both hydrogens of formaldehyde by chlorine." []
is_a: CHEBI:36687 ! acyl chloride
relationship: RO:0018038 CHEBI:16842 ! has functional parent formaldehyde

[Term]
id: CHEBI:29369
name: peroxy group
is_a: CHEBI:33246 ! inorganic group

[Term]
id: CHEBI:29377
name: sodium carbonate
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:46721 ! carbonate salt

[Term]
id: CHEBI:29389
name: silane
def: "The simplest silane, consisting of a single silicon atom carrying four hydrogens." []
is_a: CHEBI:37172 ! silanes
is_a: CHEBI:37176 ! mononuclear parent hydride

[Term]
id: CHEBI:29390
name: silicon carbide
is_a: CHEBI:25713 ! organosilicon compound

[Term]
id: CHEBI:29412
name: oxonium
is_a: CHEBI:33693 ! oxygen hydride
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:15377 ! is protonated form of water

[Term]
id: CHEBI:29415
name: dioxidochlorine(.)
is_a: CHEBI:52357 ! chlorine dioxide

[Term]
id: CHEBI:29438
name: methanide
is_a: CHEBI:38222 ! hydrocarbyl anion
relationship: RO:0018033 CHEBI:16183 ! is deprotonated form of methane
relationship: RO:0018034 CHEBI:29360 ! is protonated form of methanediide

[Term]
id: CHEBI:29449
name: hydrogen azide
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018034 CHEBI:40910 ! is protonated form of azide anion

[Term]
id: CHEBI:2948
name: azathioprine
def: "A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:35666 ! thiopurine
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:35716 ! C-nitro compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:2953
name: azinphos-methyl
def: "A member of the class of  benzotriazines that is  1,2,3-benzotriazine substituted by an oxo group at position 4 and a [(dimethoxyphosphorothioyl)sulfanyl]methyl group at position 3." []
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:51361 ! benzotriazines
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018040 CHEBI:38586 ! has parent hydride 1,2,3-benzotriazine

[Term]
id: CHEBI:29534
name: avermectin B1a
is_a: CHEBI:50344 ! avermectin

[Term]
id: CHEBI:29537
name: avermectin B1b
is_a: CHEBI:50344 ! avermectin

[Term]
id: CHEBI:2955
name: azithromycin
def: "A macrolide antibiotic useful for the treatment of bacterial infections." []
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:28963 ! amino sugar
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:231550 ! is deprotonated form of azithromycin(2+)

[Term]
id: CHEBI:2962
name: kresoxim-methyl
def: "A carboxylic ester that is the methyl ester of (2<i>E</i>)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36816 ! oxime O-ether
is_a: CHEBI:86488 ! methoxyiminoacetate strobilurin antifungal agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38499 ! has role mitochondrial cytochrome-bc1 complex inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:29678
name: sodium arsenite
def: "An inoganic sodium salt with formula with formula NaAsO<small><sub>2</sub></small>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22632 ! arsenic molecular entity
is_a: CHEBI:38702 ! inorganic sodium salt
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:33288 ! has role rodenticide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:29699
name: tunicamycin
def: "A mixture of antiviral nucleoside antibiotics produced by <em>Streptomyces lysosuperificus</em>. It contains at least 10 homologues comprising uracil, <em>N</em>-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine.  The homologues vary in the composition of the fatty acid moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:64228 ! has part tunicamycin A0
relationship: BFO:0000051 CHEBI:64245 ! has part tunicamycin A1
relationship: BFO:0000051 CHEBI:64246 ! has part tunicamycin A2
relationship: BFO:0000051 CHEBI:64248 ! has part tunicamycin B1
relationship: BFO:0000051 CHEBI:64250 ! has part tunicamycin B2
relationship: BFO:0000051 CHEBI:64255 ! has part tunicamycin B3
relationship: BFO:0000051 CHEBI:64256 ! has part tunicamycin C1
relationship: BFO:0000051 CHEBI:64257 ! has part tunicamycin C2
relationship: BFO:0000051 CHEBI:64271 ! has part tunicamycin D1
relationship: BFO:0000051 CHEBI:64272 ! has part tunicamycin D2
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0000087 CHEBI:64237 ! has role EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor

[Term]
id: CHEBI:29700
name: tylactone
def: "A 16-membererd macrolide that is the aglycone of the antibiotic 5-<em>O</em>-β-<small>D</small>-mycaminosyltylactone." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23824 ! diol
is_a: CHEBI:25106 ! macrolide
is_a: CHEBI:51689 ! enone
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:29747
name: cholate
def: "A bile acid anion that is the conjugate base of cholic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131878 ! cholanic acid anion
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16359 ! is deprotonated form of cholic acid

[Term]
id: CHEBI:29749
name: trans-ferulate
def: "A monocarboxylic acid anion obtained by the deprotonation of the carboxy group of ferulic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:17620 ! is deprotonated form of trans-ferulic acid

[Term]
id: CHEBI:29751
name: (-)-quinate
def: "A quinate that is the conjugate base of (−)-quinic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26490 ! quinate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:17521 ! is deprotonated form of (-)-quinic acid

[Term]
id: CHEBI:29754
name: arsonate(2-)
is_a: CHEBI:35776 ! arsenic oxoanion
relationship: RO:0018033 CHEBI:64448 ! is deprotonated form of arsonate(1-)

[Term]
id: CHEBI:29755
name: arsanide
is_a: CHEBI:35822 ! arsenic hydride
relationship: RO:0018033 CHEBI:47217 ! is deprotonated form of arsane

[Term]
id: CHEBI:29772
name: hydroxyazanide
def: "An inorganic anion that is the conjugate base of hydroxylamine, arising from deprotonation of the amino function." []
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:15429 ! is deprotonated form of hydroxylamine
relationship: RO:0018036 CHEBI:29773 ! is tautomer of aminooxidanide
relationship: RO:0018040 CHEBI:29337 ! has parent hydride azanide

[Term]
id: CHEBI:29773
name: aminooxidanide
is_a: CHEBI:33458 ! nitrogen oxoanion
relationship: RO:0018033 CHEBI:15429 ! is deprotonated form of hydroxylamine
relationship: RO:0018036 CHEBI:29772 ! is tautomer of hydroxyazanide

[Term]
id: CHEBI:29785
name: nitro group
is_a: CHEBI:33246 ! inorganic group
is_a: CHEBI:51144 ! nitrogen group

[Term]
id: CHEBI:29792
name: hydroperoxy group
is_a: CHEBI:33246 ! inorganic group

[Term]
id: CHEBI:29793
name: hydridodioxygen(1+)
is_a: CHEBI:33693 ! oxygen hydride
relationship: RO:0018034 CHEBI:15379 ! is protonated form of dioxygen

[Term]
id: CHEBI:29805
name: glycolate
def: "A hydroxy monocarboxylic acid anion that is acetate where the methyl group has been hydroxylated." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018033 CHEBI:17497 ! is deprotonated form of glycolic acid
relationship: RO:0018038 CHEBI:30089 ! has functional parent acetate

[Term]
id: CHEBI:29806
name: fumarate(2-)
def: "A C4-dicarboxylate that is the <i>E</i>-isomer of but-2-enedioate(2−)" []
synonym: "(2E)-but-2-enedioate" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36180 ! butenedioate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:37154 ! is deprotonated form of fumarate(1-)

[Term]
id: CHEBI:29807
name: glycyrrhizinate(3-)
def: "A tricarboxylic acid trianion that is the conjugate base of glycyrrhizinic acid." []
is_a: CHEBI:27092 ! tricarboxylic acid trianion
relationship: RO:0018033 CHEBI:15939 ! is deprotonated form of glycyrrhizinic acid

[Term]
id: CHEBI:29822
name: sulfinyl group
is_a: CHEBI:33246 ! inorganic group

[Term]
id: CHEBI:29840
name: arsinic acid
is_a: CHEBI:33407 ! arsenic oxoacid
relationship: RO:0018034 CHEBI:29846 ! is protonated form of arsinate

[Term]
id: CHEBI:29846
name: arsinate
is_a: CHEBI:35776 ! arsenic oxoanion
relationship: RO:0018033 CHEBI:29840 ! is deprotonated form of arsinic acid

[Term]
id: CHEBI:29850
name: arsonic acid
is_a: CHEBI:50955 ! arsonic acids
relationship: RO:0018034 CHEBI:64448 ! is protonated form of arsonate(1-)

[Term]
id: CHEBI:29852
name: methylarsonic acid
synonym: "Methylarsonic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22638 ! organoarsonic acid
is_a: CHEBI:50955 ! arsonic acids
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018034 CHEBI:33409 ! is protonated form of methylarsonate(1-)

[Term]
id: CHEBI:29864
name: mannitol
def: "A hexitol produced by a variety of organisms including bacteria, fungi, lichens and plants." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24583 ! hexitol
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:29865
name: benzo[a]pyrene
def: "An <em>ortho</em>- and <em>peri</em>-fused polycyclic arene consisting of five fused benzene rings." []
is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:29866
name: arsenite(3-)
def: "An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid." []
synonym: "Arsenite" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22633 ! arsenite ion
is_a: CHEBI:79387 ! trivalent inorganic anion
relationship: RO:0018033 CHEBI:29243 ! is deprotonated form of arsenite(2-)

[Term]
id: CHEBI:29888
name: diphosphoric acid
def: "An acyclic phosphorus acid anhydride obtained by condensation of two molecules of phosphoric acid." []
is_a: CHEBI:33457 ! phosphorus oxoacid
is_a: CHEBI:37786 ! acyclic phosphorus acid anhydride
is_a: CHEBI:62889 ! organic diphosphate
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:33017 ! is protonated form of diphosphate(1-)

[Term]
id: CHEBI:29917
name: thiol group
is_a: CHEBI:33246 ! inorganic group
relationship: RO:0018037 CHEBI:16136 ! is substitutent group from hydrogen sulfide

[Term]
id: CHEBI:29919
name: hydrosulfide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33535 ! sulfur hydride
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16136 ! is deprotonated form of hydrogen sulfide
relationship: RO:0018034 CHEBI:15138 ! is protonated form of sulfide(2-)

[Term]
id: CHEBI:29922
name: sulfo group
is_a: CHEBI:33246 ! inorganic group
relationship: RO:0018037 CHEBI:29214 ! is substitutent group from sulfonic acid

[Term]
id: CHEBI:29938
name: phosphanide
is_a: CHEBI:35879 ! phosphorus hydride
relationship: RO:0018033 CHEBI:30278 ! is deprotonated form of phosphane

[Term]
id: CHEBI:29985
name: L-glutamate(1-)
def: "An α-amino-acid anion that is the conjugate base of <small>L</small>-glutamic acid, having anionic carboxy groups and a cationic amino group" []
synonym: "L-glutamate" EXACT [ChEBI]
is_a: CHEBI:14321 ! glutamate(1-)
relationship: RO:0000087 CHEBI:24319 ! has role EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16015 ! is deprotonated form of L-glutamic acid
relationship: RO:0018034 CHEBI:29988 ! is protonated form of L-glutamate(2-)
relationship: RO:0018039 CHEBI:29986 ! is enantiomer of D-glutamate(1-)

[Term]
id: CHEBI:29986
name: D-glutamate(1-)
def: "An α-amino-acid anion that is the conjugate base of <small>D</small>-glutamic acid, having anionic carboxy groups and a cationic amino group" []
is_a: CHEBI:14321 ! glutamate(1-)
relationship: RO:0018033 CHEBI:15966 ! is deprotonated form of D-glutamic acid
relationship: RO:0018034 CHEBI:29989 ! is protonated form of D-glutamate(2-)
relationship: RO:0018039 CHEBI:29985 ! is enantiomer of L-glutamate(1-)

[Term]
id: CHEBI:29987
name: glutamate(2-)
def: "A dicarboxylic acid dianion that is the conjugate base of glutamate(1−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:14321 ! is deprotonated form of glutamate(1-)

[Term]
id: CHEBI:29988
name: L-glutamate(2-)
def: "An <small>L</small>-α-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of <small>L</small>-glutamic acid." []
is_a: CHEBI:29987 ! glutamate(2-)
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:29985 ! is deprotonated form of L-glutamate(1-)
relationship: RO:0018039 CHEBI:29989 ! is enantiomer of D-glutamate(2-)

[Term]
id: CHEBI:29989
name: D-glutamate(2-)
is_a: CHEBI:29987 ! glutamate(2-)
relationship: RO:0018033 CHEBI:29986 ! is deprotonated form of D-glutamate(1-)
relationship: RO:0018039 CHEBI:29988 ! is enantiomer of L-glutamate(2-)

[Term]
id: CHEBI:29990
name: D-aspartate(1-)
def: "An aspartate(1−) that is the conjugate base of <small>D</small>-aspartic acid." []
is_a: CHEBI:35391 ! aspartate(1-)
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17364 ! is deprotonated form of D-aspartic acid
relationship: RO:0018034 CHEBI:29994 ! is protonated form of D-aspartate(2-)
relationship: RO:0018039 CHEBI:29991 ! is enantiomer of L-aspartate(1-)

[Term]
id: CHEBI:29991
name: L-aspartate(1-)
def: "An aspartate(1−) that is the  conjugate base of <small>L</small>-aspartic acid." []
synonym: "L-aspartate" EXACT [ChEBI]
is_a: CHEBI:35391 ! aspartate(1-)
is_a: CHEBI:59869 ! L-alpha-amino acid zwitterion
is_a: CHEBI:62031 ! polar amino acid zwitterion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17053 ! is deprotonated form of L-aspartic acid
relationship: RO:0018034 CHEBI:29993 ! is protonated form of L-aspartate(2-)
relationship: RO:0018039 CHEBI:29990 ! is enantiomer of D-aspartate(1-)

[Term]
id: CHEBI:29993
name: L-aspartate(2-)
def: "An aspartate(2−) that is the conjugate base of  <small>L</small>-aspartate(1−)." []
is_a: CHEBI:29995 ! aspartate(2-)
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:29991 ! is deprotonated form of L-aspartate(1-)
relationship: RO:0018039 CHEBI:29994 ! is enantiomer of D-aspartate(2-)

[Term]
id: CHEBI:29994
name: D-aspartate(2-)
def: "An aspartate(2−) that is the conjugate base of <small>D</small>-aspartate(1−)." []
is_a: CHEBI:29995 ! aspartate(2-)
relationship: RO:0018033 CHEBI:29990 ! is deprotonated form of D-aspartate(1-)
relationship: RO:0018039 CHEBI:29993 ! is enantiomer of L-aspartate(2-)

[Term]
id: CHEBI:29995
name: aspartate(2-)
def: "A C4-dicarboxylate that is the dianion obtained by the deprotonation of both the carboxy groups of aspartic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132943 ! aspartate
is_a: CHEBI:61336 ! C4-dicarboxylate
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:35391 ! is deprotonated form of aspartate(1-)

[Term]
id: CHEBI:30031
name: succinate(2-)
def: "A dicarboxylic acid dianion resulting from the removal of a proton from both of the carboxy groups of succinic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26806 ! succinate
is_a: CHEBI:61336 ! C4-dicarboxylate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:30779 ! is deprotonated form of succinate(1-)

[Term]
id: CHEBI:30043
name: terephthalate(2-)
def: "A dicarboxylic acid dianion obtained by the deprotonation of the carboxy groups of terephthalic acid." []
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0018033 CHEBI:30801 ! is deprotonated form of terephthalate(1-)

[Term]
id: CHEBI:30045
name: divanadium pentaoxide
is_a: CHEBI:35174 ! vanadium oxide

[Term]
id: CHEBI:30049
name: teichoic acid
def: "Bacterial polysaccharide derivatives of glycerol phosphate or ribitol phosphate linked via phosphodiester bonds, whose main function is to fortify the cell wall. In some parasites, they serve as a site of attachment to mucosal membranes." []
is_a: CHEBI:65212 ! polysaccharide derivative

[Term]
id: CHEBI:30065
name: thioglycolic acid
is_a: CHEBI:33576 ! sulfur-containing carboxylic acid
relationship: RO:0018034 CHEBI:30066 ! is protonated form of thioglycolate(1-)

[Term]
id: CHEBI:30066
name: thioglycolate(1-)
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:30065 ! is deprotonated form of thioglycolic acid
relationship: RO:0018034 CHEBI:47869 ! is protonated form of thioglycolate(2-)
relationship: RO:0018038 CHEBI:29805 ! has functional parent glycolate

[Term]
id: CHEBI:30087
name: guanidinium
is_a: CHEBI:60251 ! guanidinium ion
relationship: RO:0018034 CHEBI:42820 ! is protonated form of guanidine
relationship: RO:0018034 CHEBI:616459 ! is protonated form of carbamimidoylazanium

[Term]
id: CHEBI:30089
name: acetate
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15366 ! is deprotonated form of acetic acid

[Term]
id: CHEBI:30095
name: hydrazinide
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018033 CHEBI:15571 ! is deprotonated form of hydrazine
relationship: RO:0018034 CHEBI:30100 ! is protonated form of hydrazine-1,2-diide
relationship: RO:0018034 CHEBI:30101 ! is protonated form of hydrazine-1,1-diide

[Term]
id: CHEBI:30096
name: diazene
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018034 CHEBI:30103 ! is protonated form of diazenide

[Term]
id: CHEBI:30099
name: diazynediium
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018034 CHEBI:30102 ! is protonated form of diazynium

[Term]
id: CHEBI:30100
name: hydrazine-1,2-diide
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018033 CHEBI:30095 ! is deprotonated form of hydrazinide
relationship: RO:0018034 CHEBI:30104 ! is protonated form of diazanetriide

[Term]
id: CHEBI:30101
name: hydrazine-1,1-diide
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018033 CHEBI:30095 ! is deprotonated form of hydrazinide
relationship: RO:0018034 CHEBI:30104 ! is protonated form of diazanetriide

[Term]
id: CHEBI:30102
name: diazynium
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018033 CHEBI:30099 ! is deprotonated form of diazynediium
relationship: RO:0018034 CHEBI:17997 ! is protonated form of dinitrogen

[Term]
id: CHEBI:30103
name: diazenide
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018033 CHEBI:30096 ! is deprotonated form of diazene
relationship: RO:0018034 CHEBI:29277 ! is protonated form of dinitride(2-)

[Term]
id: CHEBI:30104
name: diazanetriide
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018033 CHEBI:30100 ! is deprotonated form of hydrazine-1,2-diide
relationship: RO:0018033 CHEBI:30101 ! is deprotonated form of hydrazine-1,1-diide
relationship: RO:0018034 CHEBI:29278 ! is protonated form of dinitride(4-)

[Term]
id: CHEBI:30105
name: diazo group
is_a: CHEBI:33246 ! inorganic group
relationship: RO:0018037 CHEBI:30096 ! is substitutent group from diazene

[Term]
id: CHEBI:30106
name: azo group
is_a: CHEBI:33246 ! inorganic group
relationship: RO:0018037 CHEBI:30096 ! is substitutent group from diazene

[Term]
id: CHEBI:30123
name: trifluorochlorine
is_a: CHEBI:37765 ! halohalide

[Term]
id: CHEBI:3013
name: bendroflumethiazide
def: "A sulfonamide consisting of 7-sulfamoyl-3,4-dihydro-2<em>H</em>-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by a trifluoromethyl group and that at position 3 is substituted by a benzyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:50265 ! benzothiadiazine
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35498 ! has role diuretic
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent

[Term]
id: CHEBI:30145
name: lithium atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22314 ! alkali metal atom
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent

[Term]
id: CHEBI:3015
name: benomyl
def: "A member of the class of benzimidazoles that is the methyl ester of  [1-(butylcarbamoyl)-1<em>H</em>-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of <em>Ascomycetes</em> and <em>Fungi Imperfecti</em> in a wide range of crops." []
is_a: CHEBI:62733 ! aromatic amide
is_a: CHEBI:87036 ! benzimidazole fungicide
is_a: CHEBI:87064 ! benzimidazolylcarbamate fungicide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:35443 ! has role anthelminthic drug
relationship: RO:0000087 CHEBI:61951 ! has role microtubule-destabilising agent
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:30163
name: diboron trioxide
def: "A boron oxide with formula B<small><sub>2</sub></small>O<small><sub>3</sub></small>." []
is_a: CHEBI:35777 ! boron oxide

[Term]
id: CHEBI:3018
name: bentazone
def: "A  benzothiadiazine that is 1<em>H</em>-2,1,3-benzothiadiazin-4(3<em>H</em>)-one 2,2-dioxide substituted by an isopropyl group at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50265 ! benzothiadiazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:30181
name: plumbane
is_a: CHEBI:37176 ! mononuclear parent hydride
is_a: CHEBI:37184 ! lead hydride

[Term]
id: CHEBI:30182
name: tetraethyllead
def: "An organolead compound consisting of four ethyl groups joined to a central lead atom." []
is_a: CHEBI:33586 ! organolead compound
relationship: RO:0018040 CHEBI:30181 ! has parent hydride plumbane

[Term]
id: CHEBI:30183
name: tetramethyllead
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33586 ! organolead compound
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:747331 ! has role plastic stabilizer

[Term]
id: CHEBI:30187
name: aluminium oxide
is_a: CHEBI:33623 ! aluminium oxides

[Term]
id: CHEBI:30212
name: photon
def: "Particle of zero charge, zero rest mass, spin quantum number 1, energy <em>h</em><em>ν</em> and momentum <em>h</em><em>ν</em>/<em>c</em> (<em>h</em> is the Planck constant, <em>ν</em> the frequency of radiation and <em>c</em> the speed of light), carrier of electromagnetic force." []
is_a: CHEBI:36341 ! boson

[Term]
id: CHEBI:30217
name: helium atom
is_a: CHEBI:33309 ! noble gas atom
is_a: CHEBI:33559 ! s-block element atom
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:30231
name: nitrogen trifluoride
is_a: CHEBI:37381 ! nitrogen halide

[Term]
id: CHEBI:30245
name: linoleate
def: "An octadecadienoate with <i>cis</i>- double bonds at the 9- and 12- positions; the conjugate base of linoleic acid." []
is_a: CHEBI:25626 ! octadecadienoate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018033 CHEBI:17351 ! is deprotonated form of linoleic acid
relationship: RO:0018038 CHEBI:146293 ! has functional parent 9-HPODE(1-)

[Term]
id: CHEBI:30251
name: pentacarbonyliron
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33892 ! iron coordination entity
is_a: CHEBI:36604 ! metal carbonyl
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound

[Term]
id: CHEBI:30256
name: thiocarbonyl group
is_a: CHEBI:51422 ! organodiyl group

[Term]
id: CHEBI:30259
name: 1,3,5-triazine
is_a: CHEBI:26588 ! 1,3,5-triazines
is_a: CHEBI:38056 ! triazine

[Term]
id: CHEBI:30260
name: cyromazine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38175 ! triamino-1,3,5-triazine
relationship: RO:0000087 CHEBI:38060 ! has role triazine insecticide
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:30263
name: terbutylazine
def: "A diamino-1,3,5-triazine that is <em>N</em>-<em>tert</em>-butyl-<em>N</em>'-methyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6." []
is_a: CHEBI:38168 ! chloro-1,3,5-triazine
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:27726 ! has functional parent 6-chloro-1,3,5-triazine-2,4-diamine

[Term]
id: CHEBI:30264
name: simeton
def: "A methoxy-1,3,5-triazine that is  6-methoxy-1,3,5-triazine-2,4-diamine in which one of the hydrogens of each amino group has been replaced by an ethyl group." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38930 ! has functional parent 6-methoxy-1,3,5-triazine-2,4-diamine

[Term]
id: CHEBI:30272
name: arsonium
is_a: CHEBI:35822 ! arsenic hydride
is_a: CHEBI:50313 ! onium cation
is_a: CHEBI:62607 ! arsonium ion
relationship: RO:0018034 CHEBI:47217 ! is protonated form of arsane

[Term]
id: CHEBI:30278
name: phosphane
def: "The simplest phosphine, consisting of a single phosphorus atom with three hydrogens attached." []
is_a: CHEBI:35878 ! phosphanes
is_a: CHEBI:35883 ! phosphine
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0000087 CHEBI:39277 ! has role fumigant insecticide
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018033 CHEBI:30282 ! is deprotonated form of phosphonium
relationship: RO:0018034 CHEBI:29938 ! is protonated form of phosphanide

[Term]
id: CHEBI:30282
name: phosphonium
is_a: CHEBI:35879 ! phosphorus hydride
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:30278 ! is protonated form of phosphane

[Term]
id: CHEBI:30288
name: stibane
is_a: CHEBI:36918 ! antimony hydride
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0018033 CHEBI:30292 ! is deprotonated form of stibonium

[Term]
id: CHEBI:30292
name: stibonium
is_a: CHEBI:36918 ! antimony hydride
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:30288 ! is protonated form of stibane

[Term]
id: CHEBI:30304
name: antimony(0)
is_a: CHEBI:36922 ! elemental antimony

[Term]
id: CHEBI:30313
name: lipoate
def: "A thia fatty acid anion that is the conjugate base of lipoic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:59848 ! thia fatty acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:16494 ! is deprotonated form of lipoic acid
relationship: RO:0018038 CHEBI:25646 ! has functional parent octanoate

[Term]
id: CHEBI:30320
name: thioacetate
is_a: CHEBI:35367 ! thiocarboxylic acid anion
relationship: RO:0018033 CHEBI:26952 ! is deprotonated form of thioacetic acid

[Term]
id: CHEBI:30334
name: phosphorus trichloride
def: "A phosphorus halide with formula Cl<small><sub>3</sub></small>P." []
is_a: CHEBI:37378 ! phosphorus halide

[Term]
id: CHEBI:30335
name: phosphorus pentachloride
is_a: CHEBI:37378 ! phosphorus halide

[Term]
id: CHEBI:30336
name: phosphoryl trichloride
is_a: CHEBI:50536 ! phosphorus coordination entity

[Term]
id: CHEBI:30347
name: ethylenediamine
def: "An alkane-α,ω-diamine in which the alkane is ethane." []
is_a: CHEBI:35411 ! alkane-alpha,omega-diamine
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:51373 ! has role GABA agonist
relationship: RO:0018040 CHEBI:42266 ! has parent hydride ethane

[Term]
id: CHEBI:30351
name: 2,2'-bipyridine
def: "A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35545 ! bipyridine
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:38161 ! has role chelator

[Term]
id: CHEBI:30353
name: isopropyl group
is_a: CHEBI:22323 ! alkyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group
relationship: RO:0018037 CHEBI:32879 ! is substitutent group from propane

[Term]
id: CHEBI:30355
name: tert-butyl group
is_a: CHEBI:22323 ! alkyl group
relationship: RO:0018037 CHEBI:30363 ! is substitutent group from isobutane

[Term]
id: CHEBI:30356
name: isobutyl group
is_a: CHEBI:22323 ! alkyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group
relationship: RO:0018037 CHEBI:30363 ! is substitutent group from isobutane

[Term]
id: CHEBI:30362
name: isopentane
def: "An alkane that is butane substituted by a methyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:30363
name: isobutane
def: "An alkane that is propane substituted by a methyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:78017 ! has role food propellant
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:30367
name: pyrazol-1-ide
is_a: CHEBI:38596 ! pyrazolide
relationship: RO:0018033 CHEBI:17241 ! is deprotonated form of 1H-pyrazole

[Term]
id: CHEBI:30372
name: tetracarbonylnickel
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35438 ! nickel coordination entity
is_a: CHEBI:36604 ! metal carbonyl
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound

[Term]
id: CHEBI:30411
name: cobalamin
def: "A cobalt-corrinoid hexaamide that is cobalamin with the oxidation state of the central cobalt atom unspecified." []
is_a: CHEBI:23334 ! cobalamins
relationship: RO:0000087 CHEBI:26348 ! has role prosthetic group
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:30412
name: monoatomic dication
is_a: CHEBI:23906 ! monoatomic cation

[Term]
id: CHEBI:30430
name: indium atom
def: "A metallic element first identified and named from the brilliant indigo (Latin <em>indicum</em>) blue line in its flame spectrum." []
is_a: CHEBI:233500 ! post-transition metal atom
is_a: CHEBI:33317 ! boron group element atom

[Term]
id: CHEBI:30434
name: selenium hexafluoride
is_a: CHEBI:50093 ! selenium coordination entity

[Term]
id: CHEBI:30440
name: thallium atom
def: "A metallic element first identified and named from the brilliant green line in its flame spectrum (from Greek θαλλοσ, a green shoot)." []
is_a: CHEBI:233500 ! post-transition metal atom
is_a: CHEBI:33317 ! boron group element atom

[Term]
id: CHEBI:30441
name: germanium atom
is_a: CHEBI:137980 ! metalloid atom
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33306 ! carbon group element atom

[Term]
id: CHEBI:30443
name: germane
is_a: CHEBI:33587 ! germanium hydride
is_a: CHEBI:37176 ! mononuclear parent hydride

[Term]
id: CHEBI:30452
name: tellurium atom
is_a: CHEBI:137980 ! metalloid atom
is_a: CHEBI:33303 ! chalcogen

[Term]
id: CHEBI:30469
name: tellurium hexafluoride
is_a: CHEBI:36651 ! tellurium coordination entity

[Term]
id: CHEBI:30473
name: fentin hydroxide
def: "An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a hydroxy group. A fungicide used to control a variety of infections including blight on potatoes, leaf spot on sugar beet and alternaria blight on carrots." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24651 ! hydroxides
is_a: CHEBI:25717 ! organotin compound
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:30537 ! has functional parent triphenylstannane

[Term]
id: CHEBI:30485
name: selenonium
is_a: CHEBI:36903 ! selenium hydride
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:16503 ! is protonated form of selane

[Term]
id: CHEBI:30488
name: sulfonium
is_a: CHEBI:26830 ! sulfonium compound
is_a: CHEBI:33535 ! sulfur hydride
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:16136 ! is protonated form of hydrogen sulfide

[Term]
id: CHEBI:30494
name: oxygen difluoride
is_a: CHEBI:50081 ! oxygen halide

[Term]
id: CHEBI:30495
name: sulfur tetrafluoride
is_a: CHEBI:50094 ! sulfur coordination entity

[Term]
id: CHEBI:30496
name: sulfur hexafluoride
def: "A sulfur coordination entity consisting of six fluorine atoms attached to a central sulfur atom. It is the most potent greenhouse gas currently known, with a global warming potential of 23,900 times that of CO<small><sub>2</sub></small> over a 100 year period (SF<small><sub>6</sub></small> has an estimated lifetime in the atmosphere of between 800 and 3,000 years)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50094 ! sulfur coordination entity
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:37337 ! has role ultrasound contrast agent
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas

[Term]
id: CHEBI:30501
name: beryllium atom
def: "Alkaline earth metal atom with atomic number 4." []
is_a: CHEBI:22313 ! alkaline earth metal atom
is_a: CHEBI:88184 ! metal allergen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:53000 ! has role epitope
relationship: RO:0000087 CHEBI:60809 ! has role adjuvant

[Term]
id: CHEBI:30512
name: silver atom
is_a: CHEBI:33366 ! copper group element atom

[Term]
id: CHEBI:30513
name: antimony atom
is_a: CHEBI:137980 ! metalloid atom
is_a: CHEBI:33300 ! pnictogen

[Term]
id: CHEBI:30514
name: caesium atom
is_a: CHEBI:22314 ! alkali metal atom
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:30526
name: 1-aminocyclopropanecarboxylate
def: "An α-amino-acid anion resulting from the deprotonation of the carboxy group of 1-aminocyclopropanecarboxylic acid." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:18053 ! is deprotonated form of 1-aminocyclopropanecarboxylic acid
relationship: RO:0018033 CHEBI:58360 ! is deprotonated form of 1-aminocyclopropanecarboxylic acid zwitterion
relationship: RO:0018038 CHEBI:36128 ! has functional parent cyclopropanecarboxylate

[Term]
id: CHEBI:30527
name: flavin
def: "A derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[<em>g</em>]pteridine-2,4(3<em>H</em>,10<em>H</em>)-dione) skeleton, with a substituent on the 10 position." []
is_a: CHEBI:38925 ! benzopteridine
relationship: RO:0018034 CHEBI:60531 ! is protonated form of flavin(1-)
relationship: RO:0018038 CHEBI:37323 ! has functional parent 7,8-dimethylisoalloxazine

[Term]
id: CHEBI:30528
name: vanadium oxoanion
is_a: CHEBI:35166 ! vanadium coordination entity
is_a: CHEBI:35405 ! transition element oxoanion

[Term]
id: CHEBI:30537
name: triphenylstannane
is_a: CHEBI:25717 ! organotin compound

[Term]
id: CHEBI:30563
name: silicon dioxide
def: "A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens." []
is_a: CHEBI:33327 ! silicon oxide
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:30566
name: gamma-aminobutyrate
def: "An γ-amino acid anion resulting from the deprotonation of the carboxy group of γ-aminobutyric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:71666 ! gamma-amino acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16865 ! is deprotonated form of gamma-aminobutyric acid
relationship: RO:0018038 CHEBI:17968 ! has functional parent butyrate

[Term]
id: CHEBI:305790
name: thyroxine zwitterion
def: "The amino acid zwitterion formed from thyroxine by transfer of a proton from the carboxy group to the amino group.  Major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:30660 ! is tautomer of thyroxine

[Term]
id: CHEBI:30616
name: ATP(4-)
def: "A nucleoside triphosphate(4−) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:61557 ! nucleoside 5'-triphoshate(4-)
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:57299 ! is deprotonated form of ATP(3-)

[Term]
id: CHEBI:30621
name: diarsenic trioxide
def: "An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50527 ! arsenic oxide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:30623
name: oxalate(2-)
def: "A dicarboxylic acid dianion obtained by deprotonation of both carboxy groups of oxalic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132952 ! oxalate
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:46904 ! is deprotonated form of oxalate(1-)

[Term]
id: CHEBI:30627
name: molybdenum trioxide
is_a: CHEBI:37775 ! molybdenum oxide

[Term]
id: CHEBI:30629
name: diethylenetriamine
is_a: CHEBI:38751 ! triamine
is_a: CHEBI:39474 ! polyazaalkane

[Term]
id: CHEBI:30653
name: homoserine
def: "An α-amino acid that is glycine substituted at the α-position by a 2-hydroxyethyl group." []
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018034 CHEBI:62980 ! is protonated form of homoserinate

[Term]
id: CHEBI:30654
name: D-homoserine
def: "The <small>D</small>-enantiomer of homoserine." []
is_a: CHEBI:16733 ! D-alpha-amino acid
is_a: CHEBI:30653 ! homoserine
relationship: RO:0018036 CHEBI:143081 ! is tautomer of D-homoserine zwitterion
relationship: RO:0018039 CHEBI:15699 ! is enantiomer of L-homoserine

[Term]
id: CHEBI:30659
name: D-thyroxine
def: "The <small>D</small>-enantiomer of thyroxine." []
is_a: CHEBI:30660 ! thyroxine
is_a: CHEBI:84124 ! D-tyrosine derivative
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0018039 CHEBI:18332 ! is enantiomer of L-thyroxine

[Term]
id: CHEBI:30660
name: thyroxine
def: "An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions." []
is_a: CHEBI:24863 ! iodophenol
is_a: CHEBI:24864 ! iodothyronine
is_a: CHEBI:53291 ! 2-halophenol
is_a: CHEBI:62761 ! tyrosine derivative
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0000087 CHEBI:52290 ! has role mitogen
relationship: RO:0018036 CHEBI:305790 ! is tautomer of thyroxine zwitterion

[Term]
id: CHEBI:30661
name: thyronine
def: "A tyrosine derivative where the phenolic hydrogen of tyrosine is substituted by 4-hydroxyphenyl." []
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:62761 ! tyrosine derivative
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid

[Term]
id: CHEBI:30664
name: cyclopentadiene
is_a: CHEBI:36401 ! cycloalkadiene

[Term]
id: CHEBI:30672
name: ferrocene
def: "A bis(η<small><sup>5</small></sup>-cyclopentadienyl)metal(II) having Fe(II) as the metal(II) species. The parent of the class of ferrocenes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51002 ! bis(eta(5)-cyclopentadienyl)metal(II)
is_a: CHEBI:51005 ! ferrocenes
relationship: RO:0000087 CHEBI:62803 ! has role fuel additive

[Term]
id: CHEBI:30682
name: ruthenium atom
is_a: CHEBI:33356 ! iron group element atom
is_a: CHEBI:33365 ! platinum group metal atom

[Term]
id: CHEBI:30687
name: osmium atom
is_a: CHEBI:33356 ! iron group element atom
is_a: CHEBI:33365 ! platinum group metal atom

[Term]
id: CHEBI:30721
name: epoxy group
is_a: CHEBI:24433 ! group
relationship: RO:0018037 CHEBI:27561 ! is substitutent group from oxirane

[Term]
id: CHEBI:30742
name: ethylene glycol
def: "A 1,2-glycol compound produced via reaction of ethylene oxide with water." []
synonym: "Ethylene glycol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13643 ! glycol
is_a: CHEBI:23976 ! ethanediol
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:30745
name: phenylacetic acid
def: "A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group." []
synonym: "Phenylacetic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25978 ! phenylacetic acids
relationship: RO:0000087 CHEBI:22676 ! has role auxin
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:35219 ! has role plant growth retardant
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76956 ! has role Aspergillus metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:90318 ! has role EC 6.4.1.1 (pyruvate carboxylase) inhibitor
relationship: RO:0018034 CHEBI:18401 ! is protonated form of phenylacetate
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:30746
name: benzoic acid
def: "A compound comprising a benzene ring core carrying a carboxylic acid substituent." []
synonym: "BENZOIC ACID" EXACT [PDBeChem]
synonym: "Benzoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22723 ! benzoic acids
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:64996 ! has role EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
relationship: RO:0000087 CHEBI:65001 ! has role EC 3.1.1.3 (triacylglycerol lipase) inhibitor
relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:16150 ! is protonated form of benzoate

[Term]
id: CHEBI:30751
name: formic acid
def: "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." []
synonym: "FORMIC ACID" EXACT [PDBeChem]
synonym: "Formic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0000087 CHEBI:74783 ! has role astringent
relationship: RO:0018034 CHEBI:15740 ! is protonated form of formate

[Term]
id: CHEBI:30762
name: salicylate
def: "A monohydroxybenzoate that is the conjugate base of salicylic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25388 ! monohydroxybenzoate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:16914 ! is deprotonated form of salicylic acid

[Term]
id: CHEBI:30763
name: 4-hydroxybenzoic acid
def: "A monohydroxybenzoic acid that is benzoic acid carrying a hydroxy substituent at C-4 of the benzene ring." []
synonym: "4-Hydroxybenzoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25389 ! monohydroxybenzoic acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:17879 ! is protonated form of 4-hydroxybenzoate

[Term]
id: CHEBI:30765
name: tropic acid
def: "A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a phenyl group, and one of the methyl hydrogens is substituted by a hydroxy group." []
is_a: CHEBI:35969 ! 3-hydroxy monocarboxylic acid
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:17000 ! is protonated form of tropate
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid
relationship: RO:0018038 CHEBI:48526 ! has functional parent hydratropic acid

[Term]
id: CHEBI:30766
name: (S)-tropic acid
is_a: CHEBI:30765 ! tropic acid
relationship: RO:0018038 CHEBI:43035 ! has functional parent (R)-hydratropic acid
relationship: RO:0018039 CHEBI:30767 ! is enantiomer of (R)-tropic acid

[Term]
id: CHEBI:30767
name: (R)-tropic acid
is_a: CHEBI:30765 ! tropic acid
relationship: RO:0018038 CHEBI:48527 ! has functional parent (S)-hydratropic acid
relationship: RO:0018039 CHEBI:30766 ! is enantiomer of (S)-tropic acid

[Term]
id: CHEBI:30768
name: propionic acid
def: "A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group." []
synonym: "PROPANOIC ACID" EXACT [PDBeChem]
synonym: "Propanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:26607 ! saturated fatty acid
is_a: CHEBI:26666 ! short-chain fatty acid
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug
relationship: RO:0018034 CHEBI:17272 ! is protonated form of propionate

[Term]
id: CHEBI:30769
name: citric acid
def: "A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms." []
is_a: CHEBI:27093 ! tricarboxylic acid
relationship: RO:0000087 CHEBI:232436 ! has role calcium chelator
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:35804 ! is protonated form of citrate(1-)

[Term]
id: CHEBI:30772
name: butyric acid
def: "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group." []
synonym: "BUTANOIC ACID" EXACT [PDBeChem]
synonym: "Butanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:140601 ! fatty acid 4:0
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
relationship: RO:0000087 CHEBI:131604 ! has role Mycoplasma genitalium metabolite
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0018034 CHEBI:17968 ! is protonated form of butyrate

[Term]
id: CHEBI:30775
name: fluoroacetic acid
def: "A haloacetic acid that is acetic acid in which one of the methyl hydrogens is substituted by fluorine." []
synonym: "Fluoroacetic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16277 ! haloacetic acid
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:62608 ! has role EC 4.2.1.3 (aconitate hydratase) inhibitor
relationship: RO:0018034 CHEBI:18172 ! is protonated form of fluoroacetate

[Term]
id: CHEBI:30776
name: hexanoic acid
def: "A C<small><sub>6</sub></small>, straight-chain saturated fatty acid." []
synonym: "HEXANOIC ACID" EXACT [PDBeChem]
synonym: "Hexanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17120 ! is protonated form of hexanoate

[Term]
id: CHEBI:30778
name: gallic acid
def: "A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5." []
synonym: "3,4,5-Trihydroxybenzoic acid" EXACT [KEGG_COMPOUND]
synonym: "3,4,5-trihydroxybenzoic acid" EXACT [ChEBI]
is_a: CHEBI:27115 ! trihydroxybenzoic acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50629 ! has role cyclooxygenase 2 inhibitor
relationship: RO:0000087 CHEBI:64996 ! has role EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:74783 ! has role astringent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:16918 ! is protonated form of gallate

[Term]
id: CHEBI:30779
name: succinate(1-)
def: "A dicarboxylic acid monoanion resulting from the removal of a proton from one of the carboxy groups of succinic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26806 ! succinate
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:15741 ! is deprotonated form of succinic acid
relationship: RO:0018034 CHEBI:30031 ! is protonated form of succinate(2-)

[Term]
id: CHEBI:30780
name: maleate(2-)
def: "A C4-dicarboxylate that is the <i>Z</i>-isomer of but-2-enedioate(2−)" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132951 ! maleate
is_a: CHEBI:36180 ! butenedioate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:37156 ! is deprotonated form of maleate(1-)

[Term]
id: CHEBI:30794
name: malonic acid
def: "An α,ω-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group." []
synonym: "Propanedioic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:28383 ! alpha,omega-dicarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:30795 ! is protonated form of malonate(1-)

[Term]
id: CHEBI:30795
name: malonate(1-)
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:30794 ! is deprotonated form of malonic acid
relationship: RO:0018034 CHEBI:15792 ! is protonated form of malonate(2-)

[Term]
id: CHEBI:30800
name: phthalate(1-)
def: "A phthalate that is the conjugate base of phthalic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26092 ! phthalate
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:29069 ! is deprotonated form of phthalic acid
relationship: RO:0018034 CHEBI:17563 ! is protonated form of phthalate(2-)

[Term]
id: CHEBI:30801
name: terephthalate(1-)
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:15702 ! is deprotonated form of terephthalic acid
relationship: RO:0018034 CHEBI:30043 ! is protonated form of terephthalate(2-)

[Term]
id: CHEBI:30802
name: isophthalic acid
def: "A benzenedicarboxylic acid that is benzene substituted by carboxy groups at position 1 and 3. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and terephthalic acids." []
is_a: CHEBI:26094 ! benzenedicarboxylic acid
relationship: RO:0018034 CHEBI:30804 ! is protonated form of isophthalate(1-)

[Term]
id: CHEBI:30803
name: isophthalate(2-)
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0018033 CHEBI:30804 ! is deprotonated form of isophthalate(1-)

[Term]
id: CHEBI:30804
name: isophthalate(1-)
def: "A dicarboxylic acid monoanion that is the conjugate base of isophthalic acid." []
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:30802 ! is deprotonated form of isophthalic acid
relationship: RO:0018034 CHEBI:30803 ! is protonated form of isophthalate(2-)

[Term]
id: CHEBI:30805
name: dodecanoic acid
def: "A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil." []
synonym: "Dodecanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:18262 ! is protonated form of dodecanoate
relationship: RO:0018040 CHEBI:28817 ! has parent hydride dodecane

[Term]
id: CHEBI:30807
name: tetradecanoate
def: "A long-chain fatty acid anion that is the conjugate base of myristic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:76619 ! omega-methyl fatty acid anion
is_a: CHEBI:76928 ! 2,3-saturated fatty acid(1-)
is_a: CHEBI:78121 ! fatty acid anion 14:0
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28875 ! is deprotonated form of tetradecanoic acid

[Term]
id: CHEBI:30813
name: decanoic acid
def: "A C<small><sub>10</sub></small>, straight-chain saturated fatty acid." []
synonym: "DECANOIC ACID" EXACT [PDBeChem]
synonym: "Decanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:27689 ! is protonated form of decanoate
relationship: RO:0018040 CHEBI:41808 ! has parent hydride decane

[Term]
id: CHEBI:30816
name: vanillic acid
def: "A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3." []
synonym: "4-Hydroxy-3-methoxybenzoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25238 ! methoxybenzoic acid
is_a: CHEBI:25389 ! monohydroxybenzoic acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:16632 ! is protonated form of vanillate

[Term]
id: CHEBI:30823
name: oleate
def: "A C<small><sub>18</sub></small>, long straight-chain monounsaturated fatty acid anion; and the conjugate base of oleic acid, arising from deprotonation of the carboxylic acid group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132944 ! octadec-9-enoate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:16196 ! is deprotonated form of oleic acid

[Term]
id: CHEBI:30838
name: itaconic acid
def: "A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group." []
is_a: CHEBI:189840 ! dicarboxylic fatty acid
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17240 ! is protonated form of itaconate(2-)
relationship: RO:0018038 CHEBI:15741 ! has functional parent succinic acid

[Term]
id: CHEBI:30845
name: 2-furoic acid
def: "A furoic acid having the carboxylic acid group located at position 2." []
is_a: CHEBI:36055 ! furoic acid
relationship: RO:0000087 CHEBI:35222 ! has role inhibitor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0018034 CHEBI:16739 ! is protonated form of 2-furoate

[Term]
id: CHEBI:30848
name: urate(1-)
is_a: CHEBI:46818 ! urate anion
relationship: RO:0018034 CHEBI:27216 ! is protonated form of urate(2-)

[Term]
id: CHEBI:30853
name: glycyrrhetinic acid
def: "A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30." []
is_a: CHEBI:25872 ! pentacyclic triterpenoid
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid
is_a: CHEBI:36130 ! cyclic terpene ketone
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:17573 ! is protonated form of glycyrrhetinate
relationship: RO:0018040 CHEBI:36481 ! has parent hydride oleanane

[Term]
id: CHEBI:30854
name: indole-3-acetate
def: "An indol-3-yl carboxylic acid anion that is the conjugate base of indole-3-acetic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38468 ! indol-3-yl carboxylic acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16411 ! is deprotonated form of indole-3-acetic acid

[Term]
id: CHEBI:30879
name: alcohol
def: "A compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom." []
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:30898
name: naphthalene-2,7-disulfonic acid
def: "A naphthalenesulfonic acid in which the sulfo groups are attached to positions 2 and 7 of the naphthalene ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36336 ! naphthalenesulfonic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:3090
name: bicalutamide
def: "A racemate comprising of equal amounts of (<i>R</i>)-bicalutamide and (<i>S</i>)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:144094 ! has part (S)-bicalutamide
relationship: BFO:0000051 CHEBI:39589 ! has part (R)-bicalutamide
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35497 ! has role androgen antagonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:30911
name: glucitol
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24583 ! hexitol
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:30921
name: glutarate(2-)
def: "A dicarboxylic acid dianion obtained by deprotonation of both the carboxy groups of glutaric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24329 ! glutarate
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:35907 ! is deprotonated form of glutarate(1-)

[Term]
id: CHEBI:30924
name: L-tartrate(2-)
is_a: CHEBI:30929 ! 2,3-dihydroxybutanedioate
relationship: RO:0018033 CHEBI:35398 ! is deprotonated form of L-tartrate(1-)
relationship: RO:0018039 CHEBI:30927 ! is enantiomer of D-tartrate(2-)

[Term]
id: CHEBI:30927
name: D-tartrate(2-)
is_a: CHEBI:30929 ! 2,3-dihydroxybutanedioate
relationship: RO:0018033 CHEBI:35399 ! is deprotonated form of D-tartrate(1-)
relationship: RO:0018039 CHEBI:30924 ! is enantiomer of L-tartrate(2-)

[Term]
id: CHEBI:30929
name: 2,3-dihydroxybutanedioate
def: "A tartaric acid anion that is the conjugate base of 3-carboxy-2,3-dihydroxypropanoate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132950 ! tartrate
is_a: CHEBI:61336 ! C4-dicarboxylate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:48929 ! is deprotonated form of 3-carboxy-2,3-dihydroxypropanoate

[Term]
id: CHEBI:3093
name: bifenthrin
def: "A carboxylic ester obtained by formal condensation of <i>cis</i>-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and [(2-methyl-1,1'-biphenyl)-3-yl]methanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0000087 CHEBI:39259 ! has role pyrethroid ester acaricide
relationship: RO:0018038 CHEBI:39103 ! has functional parent cis-chrysanthemic acid

[Term]
id: CHEBI:30938
name: 6-aminopenicillanate
is_a: CHEBI:51356 ! penicillinate anion
relationship: RO:0018033 CHEBI:16705 ! is deprotonated form of 6-aminopenicillanic acid
relationship: RO:0018033 CHEBI:57869 ! is deprotonated form of 6-aminopenicillanic acid zwitterion

[Term]
id: CHEBI:3095
name: biguanide
is_a: CHEBI:53662 ! biguanides

[Term]
id: CHEBI:30956
name: trichloroacetic acid
def: "A monocarboxylic acid that is acetic acid in which all three methyl hydrogens are substituted by chlorine." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018034 CHEBI:27455 ! is protonated form of trichloroacetate
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:30958
name: Sudan I
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48959 ! monoazo compound
relationship: RO:0000087 CHEBI:37958 ! has role dye
relationship: RO:0018038 CHEBI:10432 ! has functional parent 2-naphthol

[Term]
id: CHEBI:30965
name: oxetane
def: "A saturated organic heteromonocyclic parent that is a four-membered ring comprising of three carbon atoms and an oxygen atom." []
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:38784 ! oxetanes

[Term]
id: CHEBI:30966
name: glycidol
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:32955 ! epoxide
relationship: RO:0018038 CHEBI:38685 ! has functional parent 1,2-epoxypropane

[Term]
id: CHEBI:30969
name: aziridine
synonym: "Aziridine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22681 ! aziridines
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:37949 ! azacycloalkane
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0018033 CHEBI:50929 ! is deprotonated form of aziridinium

[Term]
id: CHEBI:3098
name: bile acid
def: "Any member of a group of hydroxy-5β-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5β-configuration." []
is_a: CHEBI:138366 ! bile acids
is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid

[Term]
id: CHEBI:30985
name: 4,4'-bipyridine
def: "A  bipyridine in which the two pyridine moieties are linked by a bond between positions C-4 and C-4'." []
is_a: CHEBI:35545 ! bipyridine

[Term]
id: CHEBI:31011
name: valerate
def: "A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58951 ! short-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:17418 ! is deprotonated form of valeric acid

[Term]
id: CHEBI:31014
name: tetracosanoate
def: "A straight-chain saturated fatty acid anion that is the conjugate base of tetracosanoic acid (lignoceric acid), formed by deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58950 ! very long-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:78128 ! fatty acid anion 24:0
is_a: CHEBI:83955 ! 2-saturated fatty acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28866 ! is deprotonated form of tetracosanoic acid

[Term]
id: CHEBI:31206
name: ammonium chloride
def: "An inorganic chloride having ammonium as the counterion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36093 ! inorganic chloride
is_a: CHEBI:47704 ! ammonium salt
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor

[Term]
id: CHEBI:31209
name: ampicillin trihydrate
is_a: CHEBI:35505 ! hydrate
relationship: BFO:0000051 CHEBI:28971 ! has part ampicillin

[Term]
id: CHEBI:31225
name: antipyrine
def: "A  pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:83328 ! pyrazolone
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:73263 ! has role cyclooxygenase 3 inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:31236
name: aripiprazole
def: "An <em>N</em>-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:23765 ! quinolone
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:46845 ! N-alkylpiperazine
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:77727 ! delta-lactam
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35941 ! has role serotonergic agonist
relationship: RO:0000087 CHEBI:37955 ! has role H1-receptor antagonist
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic

[Term]
id: CHEBI:3127
name: bisoprolol
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:66991 ! has role sympatholytic agent

[Term]
id: CHEBI:31328
name: butyl acetate
def: "The acetate ester of butanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018038 CHEBI:28885 ! has functional parent butan-1-ol

[Term]
id: CHEBI:31341
name: calcium dihydroxide
is_a: CHEBI:35150 ! calcium hydroxide
relationship: RO:0000087 CHEBI:74783 ! has role astringent

[Term]
id: CHEBI:31344
name: calcium oxide
def: "A member of the class of calcium oxides of calcium and oxygen in a 1:1 ratio." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35156 ! calcium salt
is_a: CHEBI:48232 ! calcium oxides
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer

[Term]
id: CHEBI:31346
name: calcium sulfate
is_a: CHEBI:190295 ! inorganic calcium salt
is_a: CHEBI:35156 ! calcium salt
is_a: CHEBI:37826 ! sulfuric acid derivative
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:31348
name: capecitabine
def: "A carbamate ester that is cytidine in which the hydrogen at position 5 is replaced by fluorine and in which the amino group attached to position 4 is converted into its <em>N</em>-(penyloxy)carbonyl derivative. Capecitabine is a antineoplastic agent used in the treatment of cancers." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:23524 ! cytidines
is_a: CHEBI:36988 ! 5'-deoxyribonucleoside
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug

[Term]
id: CHEBI:31355
name: carboplatin
def: "A platinum coordination entity with <i>cis</i> square-planar geometry in which  platinum(II) is coordinated to two ammonia ligands and a bidentate cyclobutane-1,1-dicarboxylate ligand." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33862 ! platinum coordination entity
is_a: CHEBI:50860 ! organic molecular entity
relationship: BFO:0000051 CHEBI:35690 ! has part cyclobutane-1,1-dicarboxylate(2-)
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:3139
name: bleomycin A2
is_a: CHEBI:22907 ! bleomycin
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:31521
name: doxifluridine
def: "A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an  oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluorouracil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36988 ! 5'-deoxyribonucleoside
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:74494 ! pyrimidine 5'-deoxyribonucleoside
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug

[Term]
id: CHEBI:31556
name: esatenolol
def: "The (<i>S</i>)-enantiomer of atenolol." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:2904 ! atenolol

[Term]
id: CHEBI:31575
name: ethylparaben
def: "An ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol," []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:85122 ! paraben
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76989 ! has role phytoestrogen

[Term]
id: CHEBI:31577
name: ethylenediamine derivative
def: "Any organic amino compound that is a derivative of  ethylenediamine." []
is_a: CHEBI:50047 ! organic amino compound
relationship: RO:0018038 CHEBI:30347 ! has functional parent ethylenediamine

[Term]
id: CHEBI:31604
name: ferric ammonium citrate
def: "A mixture of indefinite composition that contains ferric and ammonium cations and citrate(3−) anions, ferric ammonium citrate may be obtained as red crystals or a brownish yellow powder or as green crystals or powder. It is added to foods as an acidity regulator and anticaking agent. It is also used as a positive oral contrast agent in magnetic resonance imaging, and was formerly administered orally as a source of iron for the treatment of iron-deficiency anaemia." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:16947 ! has part citrate(3-)
relationship: BFO:0000051 CHEBI:28938 ! has part ammonium
relationship: BFO:0000051 CHEBI:29034 ! has part iron(3+)
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:37335 ! has role MRI contrast agent
relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:31638
name: fulvestrant
def: "A 3-hydroxy steroid that is 17β-estradiol in which the 7α hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22063 ! sulfoxide
is_a: CHEBI:35343 ! 17beta-hydroxy steroid
is_a: CHEBI:36834 ! 3-hydroxy steroid
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50792 ! has role estrogen receptor antagonist
relationship: RO:0000087 CHEBI:50837 ! has role estrogen antagonist
relationship: RO:0018040 CHEBI:23966 ! has parent hydride estrane

[Term]
id: CHEBI:31701
name: iobitridol
def: "A benzenedicarboxamide compound having <em>N</em>-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a 3-hydroxy-2-(hydroxymethyl)propanimido at position 5." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:37206 ! hexol
is_a: CHEBI:38800 ! benzenedicarboxamide
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37338 ! has role radioopaque medium
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:31709
name: iohexol
def: "A benzenedicarboxamide compound having <em>N</em>-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an <em>N</em>-(2,3-dihydroxypropyl)acetamido group at the 5-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:38800 ! benzenedicarboxamide
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37338 ! has role radioopaque medium
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:31710
name: iomeprol
def: "A benzenedicarboxamide compound having <em>N</em>-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:38800 ! benzenedicarboxamide
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37338 ! has role radioopaque medium
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:31711
name: iopamidol
def: "A benzenedicarboxamide compound having <em>N</em>-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2<i>S</i>)-2-hydroxypropanamido group at the 5-position." []
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:37205 ! pentol
is_a: CHEBI:38800 ! benzenedicarboxamide
is_a: CHEBI:48470 ! amidobenzoic acid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37338 ! has role radioopaque medium
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:31725
name: isoamyl acetate
def: "The acetate ester of isoamylol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018038 CHEBI:15837 ! has functional parent isoamylol

[Term]
id: CHEBI:31746
name: kainic acid
is_a: CHEBI:35692 ! dicarboxylic acid
is_a: CHEBI:46767 ! pyrrolidinecarboxylic acid
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
is_a: CHEBI:84186 ! L-proline derivative
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:50103 ! has role excitatory amino acid agonist
relationship: RO:0018034 CHEBI:156548 ! is protonated form of kainate(1-)

[Term]
id: CHEBI:3177
name: bromacil
def: "A racemate consisting of equimolar concentrations of (<i>R</i>)- and (<i>S</i>)-bromacil." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83659 ! has part (R)-bromacil
relationship: BFO:0000051 CHEBI:83660 ! has part (S)-bromacil
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:31794
name: magnesium oxide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25108 ! magnesium molecular entity
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer
relationship: RO:0000087 CHEBI:65265 ! has role antacid

[Term]
id: CHEBI:31810
name: fleroxacin
def: "A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:38582 ! difluorobenzene
is_a: CHEBI:46845 ! N-alkylpiperazine
is_a: CHEBI:87211 ! fluoroquinolone antibiotic
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:53559 ! has role topoisomerase IV inhibitor

[Term]
id: CHEBI:31835
name: methylparaben
def: "A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:85122 ! paraben
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:31836
name: methylphenidate hydrochloride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:51856 ! has part methylphenidate(1+)
relationship: RO:0000087 CHEBI:35337 ! has role central nervous system stimulant
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent

[Term]
id: CHEBI:31927
name: nystatin A3
is_a: CHEBI:59676 ! nystatins

[Term]
id: CHEBI:3193
name: brucine
is_a: CHEBI:52157 ! organic heteroheptacyclic compound
is_a: CHEBI:65323 ! monoterpenoid indole alkaloid

[Term]
id: CHEBI:31941
name: oxaliplatin
def: "A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33862 ! platinum coordination entity
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:31953
name: Oxytetracycline hydrochloride
is_a: CHEBI:26895 ! tetracyclines

[Term]
id: CHEBI:31959
name: pantethine
def: "An organic disulfide that consists of two molecules of pantothenic acid linked by amide bonds to a cysteamine disulfide bridging group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:35489 ! organic disulfide
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0000087 CHEBI:23354 ! has role coenzyme
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0018038 CHEBI:33706 ! has functional parent beta-amino acid
relationship: RO:0018038 CHEBI:7916 ! has functional parent pantothenic acid

[Term]
id: CHEBI:32028
name: poly(vinyl acetate)
def: "A polymer composed of repeating acetoxyethylene units." []
is_a: CHEBI:53242 ! vinyl polymer macromolecule

[Term]
id: CHEBI:32035
name: potassium hydroxide
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:33978 ! alkali metal hydroxide

[Term]
id: CHEBI:32063
name: propylparaben
def: "The benzoate ester that is the propyl ester of 4-hydroxybenzoic acid.   Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:85122 ! paraben
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0018038 CHEBI:28831 ! has functional parent propan-1-ol

[Term]
id: CHEBI:3207
name: budesonide
def: "A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:59770 ! cyclic acetal
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:32087
name: Ramatroban
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48513 ! carbazoles
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent

[Term]
id: CHEBI:32111
name: saccharin
def: "A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:55505 ! 1,2-benzisothiazole
is_a: CHEBI:90852 ! N-sulfonylcarboxamide
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:32114
name: salicylamide
def: "The simplest member of the class of salicylamides derived from salicylic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:53443 ! salicylamides
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug

[Term]
id: CHEBI:32130
name: silver(1+) nitrate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33968 ! silver salt
is_a: CHEBI:51084 ! inorganic nitrate salt
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:74783 ! has role astringent

[Term]
id: CHEBI:32145
name: sodium hydroxide
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:33978 ! alkali metal hydroxide

[Term]
id: CHEBI:32146
name: sodium hypochlorite
def: "An inorganic sodium salt in which hypochlorite is the counterion. It is used as a bleaching and disinfecting agent and is commonly found in household bleach." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37578 ! halide
is_a: CHEBI:38702 ! inorganic sodium salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: BFO:0000051 CHEBI:29222 ! has part hypochlorite
relationship: RO:0000087 CHEBI:132717 ! has role bleaching agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:32159
name: sucralose
def: "A disaccharide derivative consisting of 4-chloro-4-deoxy-α-<small>D</small>-galactopyranose and 1,6-dichloro-1,6-dideoxy-β-<small>D</small>-fructofuranose units linked by a glycosidic bond." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:59777 ! ketal
is_a: CHEBI:63353 ! disaccharide derivative
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:3216
name: buprenorphine
def: "A morphinane alkaloid that is 7,8-dihydromorphine 6-<em>O</em>-methyl ether in which positions 6 and 14 are joined by a -CH<small><sub>2</sub></small>CH<small><sub>2</sub></small>- bridge, one of the hydrogens of the <em>N</em>-methyl group is substituted by cyclopropyl, and a hydrogen at position 7 is substituted by a 2-hydroxy-3,3-dimethylbutan-2-yl group. It is highly effective for the treatment of opioid use disorder and is also increasingly being used in the treatment of chronic pain." []
is_a: CHEBI:25418 ! morphinane alkaloid
relationship: RO:0000087 CHEBI:167165 ! has role kappa-opioid receptor antagonist
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:59283 ! has role delta-opioid receptor antagonist

[Term]
id: CHEBI:32161
name: sulfadimethoxine
def: "A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position." []
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:87228 ! sulfonamide antibiotic
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:45373 ! has functional parent sulfanilamide

[Term]
id: CHEBI:32178
name: Talc
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:3219
name: bupropion
def: "An aromatic ketone that is propiophenone carrying a <em>tert</em>-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring." []
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:76224 ! aromatic ketone
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:3220
name: Bupropion hydrochloride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:32234
name: titanium dioxide
def: "A titanium oxide with the formula TiO<small><sub>2</sub></small>.  A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134438 ! titanium oxides
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:77182 ! has role food colouring

[Term]
id: CHEBI:32246
name: tolvaptan
def: "A racemate comprising of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-tolvaptan. It is a selective vasopressin V<small><sub>2</sub></small> receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:231424 ! has part (S)-tolvaptan
relationship: BFO:0000051 CHEBI:231426 ! has part (R)-tolvaptan
relationship: RO:0000087 CHEBI:194423 ! has role aquaretic
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:59680 ! has role vasopressin receptor antagonist
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent

[Term]
id: CHEBI:32354
name: 4-hydroxybenzenesulfonic acid
def: "An arenesulfonic acid that is phenol substituted by a sulfo group at C-4." []
is_a: CHEBI:33555 ! arenesulfonic acid
relationship: RO:0018038 CHEBI:15882 ! has functional parent phenol

[Term]
id: CHEBI:32361
name: nonanoate
def: "A medium-chain fatty acid anion that is the conjugate base of nonanoic acid that in methyl ester form has significant nematicidal activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:59558 ! medium-chain fatty acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:29019 ! is deprotonated form of nonanoic acid

[Term]
id: CHEBI:32362
name: heptanoate
def: "A medium-chain fatty acid anion that is the conjugate base of heptanoic acid; shown in myocardial ischaemia/reperfusion studies to increase levels of C<small><sub>4</sub></small> Kreb's cycle intermediates." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:59558 ! medium-chain fatty acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:45571 ! is deprotonated form of heptanoic acid

[Term]
id: CHEBI:32368
name: undecanoic acid
def: "A straight-chain, eleven-carbon saturated medium-chain fatty acid found in body fluids; the most fungitoxic of the C7:0 - C18:0 fatty acid series." []
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:32369 ! is protonated form of undecanoate
relationship: RO:0018040 CHEBI:46342 ! has parent hydride undecane

[Term]
id: CHEBI:32369
name: undecanoate
def: "A medium-chain fatty acid anion that is the conjugate base of undecanoic acid; used in tandem with testosterone cation in the treatment of male hypogonadism. Major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:59558 ! medium-chain fatty acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32368 ! is deprotonated form of undecanoic acid

[Term]
id: CHEBI:32372
name: palmitoleate
def: "A hexadec-9-enoate that is the conjugate base of palmitoleic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:71449 ! hexadec-9-enoate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28716 ! is deprotonated form of palmitoleic acid

[Term]
id: CHEBI:32387
name: alpha-linolenate
def: "A linolenate that is the conjugate base of α-linolenic acid, arising from deprotonation of the carboxylic acid group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133790 ! linolenate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:27432 ! is deprotonated form of alpha-linolenic acid

[Term]
id: CHEBI:32395
name: arachidonate
def: "A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:62920 ! icosatetraenoate
is_a: CHEBI:62937 ! icosanoid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15843 ! is deprotonated form of arachidonic acid
relationship: RO:0018038 CHEBI:146291 ! has functional parent 11-HPETE(1-)

[Term]
id: CHEBI:32402
name: catecholate(2-)
def: "A phenolate anion that is the conjugate base of catecholate(1−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:50524 ! is deprotonated form of catecholate(1-)

[Term]
id: CHEBI:32431
name: L-alaninate
def: "The <small>L</small>-enantiomer of alaninate." []
is_a: CHEBI:32439 ! alaninate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:16977 ! is deprotonated form of L-alanine
relationship: RO:0018039 CHEBI:32435 ! is enantiomer of D-alaninate

[Term]
id: CHEBI:32432
name: L-alaninium
def: "The <small>L</small>-enantiomer of alaninium." []
is_a: CHEBI:32440 ! alaninium
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:16977 ! is protonated form of L-alanine
relationship: RO:0018039 CHEBI:32436 ! is enantiomer of D-alaninium

[Term]
id: CHEBI:32435
name: D-alaninate
def: "The <small>D</small>-enantiomer of alaninate." []
is_a: CHEBI:32439 ! alaninate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15570 ! is deprotonated form of D-alanine
relationship: RO:0018039 CHEBI:32431 ! is enantiomer of L-alaninate

[Term]
id: CHEBI:32436
name: D-alaninium
def: "An alaninium that is the conjugate acid of <small>D</small>-alanine." []
is_a: CHEBI:32440 ! alaninium
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:15570 ! is protonated form of D-alanine
relationship: RO:0018039 CHEBI:32432 ! is enantiomer of L-alaninium

[Term]
id: CHEBI:32439
name: alaninate
def: "An α-amino-acid anion that is the conjugate base of alanine, arising from deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018033 CHEBI:16449 ! is deprotonated form of alanine

[Term]
id: CHEBI:32440
name: alaninium
def: "An α-amino-acid cation that is the conjugate acid of alanine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018034 CHEBI:16449 ! is protonated form of alanine

[Term]
id: CHEBI:32442
name: L-cysteinate(1-)
def: "The <small>L</small>-enantiomer of cysteinate(1−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32456 ! cysteinate(1-)
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:17561 ! is deprotonated form of L-cysteine
relationship: RO:0018033 CHEBI:35235 ! is deprotonated form of L-cysteine zwitterion
relationship: RO:0018034 CHEBI:32443 ! is protonated form of L-cysteinate(2-)
relationship: RO:0018039 CHEBI:32449 ! is enantiomer of D-cysteinate(1-)

[Term]
id: CHEBI:32443
name: L-cysteinate(2-)
def: "The <small>L</small>-enantiomer of cysteinate(2−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32457 ! cysteinate(2-)
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32442 ! is deprotonated form of L-cysteinate(1-)
relationship: RO:0018039 CHEBI:32450 ! is enantiomer of D-cysteinate(2-)

[Term]
id: CHEBI:32445
name: L-cysteinium
def: "The <small>L</small>-enantiomer of cysteinium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32458 ! cysteinium
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:17561 ! is protonated form of L-cysteine
relationship: RO:0018034 CHEBI:35235 ! is protonated form of L-cysteine zwitterion
relationship: RO:0018039 CHEBI:32451 ! is enantiomer of D-cysteinium

[Term]
id: CHEBI:32449
name: D-cysteinate(1-)
def: "The <small>D</small>-enantiomer of cysteinate(1−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32456 ! cysteinate(1-)
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:16375 ! is deprotonated form of D-cysteine
relationship: RO:0018033 CHEBI:35236 ! is deprotonated form of D-cysteine zwitterion
relationship: RO:0018034 CHEBI:32450 ! is protonated form of D-cysteinate(2-)
relationship: RO:0018039 CHEBI:32442 ! is enantiomer of L-cysteinate(1-)

[Term]
id: CHEBI:3245
name: butyl acrylate
def: "An acrylate ester obtained by the formal condensation of the hydroxy group of  butan-1-ol with the carboxy group of  acrylic acid." []
is_a: CHEBI:50424 ! acrylate ester
relationship: RO:0018038 CHEBI:18308 ! has functional parent acrylic acid
relationship: RO:0018038 CHEBI:28885 ! has functional parent butan-1-ol

[Term]
id: CHEBI:32450
name: D-cysteinate(2-)
def: "The <small>D</small>-enantiomer of cysteinate(2−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32457 ! cysteinate(2-)
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32449 ! is deprotonated form of D-cysteinate(1-)
relationship: RO:0018039 CHEBI:32443 ! is enantiomer of L-cysteinate(2-)

[Term]
id: CHEBI:32451
name: D-cysteinium
def: "The <small>D</small>-enantiomer of cysteinium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32458 ! cysteinium
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:16375 ! is protonated form of D-cysteine
relationship: RO:0018034 CHEBI:35236 ! is protonated form of D-cysteine zwitterion
relationship: RO:0018039 CHEBI:32445 ! is enantiomer of L-cysteinium

[Term]
id: CHEBI:32456
name: cysteinate(1-)
def: "A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
is_a: CHEBI:63470 ! sulfur-containing amino-acid anion
relationship: RO:0018033 CHEBI:15356 ! is deprotonated form of cysteine
relationship: RO:0018033 CHEBI:35237 ! is deprotonated form of cysteine zwitterion
relationship: RO:0018034 CHEBI:32457 ! is protonated form of cysteinate(2-)

[Term]
id: CHEBI:32457
name: cysteinate(2-)
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:32456 ! is deprotonated form of cysteinate(1-)

[Term]
id: CHEBI:32458
name: cysteinium
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:15356 ! is protonated form of cysteine
relationship: RO:0018034 CHEBI:35237 ! is protonated form of cysteine zwitterion

[Term]
id: CHEBI:32486
name: L-phenylalaninate
def: "An optically active form of phenylalaninate having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32504 ! phenylalaninate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:17295 ! is deprotonated form of L-phenylalanine
relationship: RO:0018039 CHEBI:32494 ! is enantiomer of D-phenylalaninate

[Term]
id: CHEBI:32487
name: L-phenylalaninium
def: "An optically active form of phenylalaninium having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32505 ! phenylalaninium
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:17295 ! is protonated form of L-phenylalanine
relationship: RO:0018039 CHEBI:32495 ! is enantiomer of D-phenylalaninium

[Term]
id: CHEBI:32494
name: D-phenylalaninate
def: "The <small>D</small>-enantiomer of phenylalaninate." []
is_a: CHEBI:32504 ! phenylalaninate
relationship: RO:0018033 CHEBI:16998 ! is deprotonated form of D-phenylalanine
relationship: RO:0018039 CHEBI:32486 ! is enantiomer of L-phenylalaninate

[Term]
id: CHEBI:32495
name: D-phenylalaninium
def: "An optically active form of phenylalaninium having <small>D</small>-configuration." []
is_a: CHEBI:32505 ! phenylalaninium
relationship: RO:0018034 CHEBI:16998 ! is protonated form of D-phenylalanine
relationship: RO:0018039 CHEBI:32487 ! is enantiomer of L-phenylalaninium

[Term]
id: CHEBI:32497
name: thioacetamide
def: "A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47956 ! thiocarboxamide
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0018038 CHEBI:27856 ! has functional parent acetamide

[Term]
id: CHEBI:32504
name: phenylalaninate
def: "An aromatic amino-acid anion that is the conjugate base of phenylalanine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
is_a: CHEBI:63473 ! aromatic amino-acid anion
relationship: RO:0018033 CHEBI:28044 ! is deprotonated form of phenylalanine

[Term]
id: CHEBI:32505
name: phenylalaninium
def: "An α-amino-acid cation that is the conjugate acid of phenylalanine, arising from protonation of the amino group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:28044 ! is protonated form of phenylalanine

[Term]
id: CHEBI:32506
name: 4,4'-diaminodiphenylmethane
def: "An aromatic amine that is diphenylmethane substituted at the 4-position of each benzene ring by an amino group." []
synonym: "4,4'-methylenedianiline" EXACT [ChEMBL]
is_a: CHEBI:33860 ! aromatic amine
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0018040 CHEBI:38884 ! has parent hydride diphenylmethane

[Term]
id: CHEBI:32507
name: glycinium
def: "An α-amino-acid cation that is the conjugate acid of glycine, arising from protonation of the amino." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:15428 ! is protonated form of glycine

[Term]
id: CHEBI:32508
name: glycinate
def: "An α-amino-acid anion that is the conjugate base of glycine, arising from deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:15428 ! is deprotonated form of glycine

[Term]
id: CHEBI:32509
name: pirinixic acid
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38975 ! methylbenzene
is_a: CHEBI:39447 ! pyrimidines
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:32529
name: histidinate(1-)
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:27570 ! is deprotonated form of histidine
relationship: RO:0018034 CHEBI:32530 ! is protonated form of histidinate(2-)

[Term]
id: CHEBI:32530
name: histidinate(2-)
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:32529 ! is deprotonated form of histidinate(1-)

[Term]
id: CHEBI:32531
name: histidinium(1+)
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018033 CHEBI:32532 ! is deprotonated form of histidinium(2+)
relationship: RO:0018034 CHEBI:27570 ! is protonated form of histidine

[Term]
id: CHEBI:32532
name: histidinium(2+)
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:32531 ! is protonated form of histidinium(1+)

[Term]
id: CHEBI:32544
name: nicotinate
def: "A pyridinemonocarboxylate that is the conjugate base of nicotinic acid, arising from deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:176839 ! vitamin B3
is_a: CHEBI:38181 ! pyridinemonocarboxylate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:15940 ! is deprotonated form of nicotinic acid

[Term]
id: CHEBI:32550
name: L-lysinate
def: "An optically active form of lysinate having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32563 ! lysinate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:133538 ! is deprotonated form of L-lysine zwitterion
relationship: RO:0018033 CHEBI:18019 ! is deprotonated form of L-lysine
relationship: RO:0018039 CHEBI:32556 ! is enantiomer of D-lysinate

[Term]
id: CHEBI:32551
name: L-lysinium(1+)
def: "An optically active form of lysinium having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32564 ! lysinium(1+)
is_a: CHEBI:62031 ! polar amino acid zwitterion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:32552 ! is deprotonated form of L-lysinium(2+)
relationship: RO:0018034 CHEBI:133538 ! is protonated form of L-lysine zwitterion
relationship: RO:0018034 CHEBI:18019 ! is protonated form of L-lysine
relationship: RO:0018039 CHEBI:32557 ! is enantiomer of D-lysinium(1+)

[Term]
id: CHEBI:32552
name: L-lysinium(2+)
def: "The <small>L</small>-enantiomer of lysinium(2+)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32565 ! lysinium(2+)
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:32551 ! is protonated form of L-lysinium(1+)
relationship: RO:0018039 CHEBI:32558 ! is enantiomer of D-lysinium(2+)

[Term]
id: CHEBI:32556
name: D-lysinate
def: "An optically active form of lysinate having <small>D</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32563 ! lysinate
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:16855 ! is deprotonated form of D-lysine
relationship: RO:0018039 CHEBI:32550 ! is enantiomer of L-lysinate

[Term]
id: CHEBI:32557
name: D-lysinium(1+)
def: "An optically active form of lysinium having <small>D</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32564 ! lysinium(1+)
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:32558 ! is deprotonated form of D-lysinium(2+)
relationship: RO:0018034 CHEBI:16855 ! is protonated form of D-lysine
relationship: RO:0018039 CHEBI:32551 ! is enantiomer of L-lysinium(1+)

[Term]
id: CHEBI:32558
name: D-lysinium(2+)
def: "The <small>D</small>-enantiomer of lysinium(2+)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32565 ! lysinium(2+)
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018034 CHEBI:32557 ! is protonated form of D-lysinium(1+)
relationship: RO:0018039 CHEBI:32552 ! is enantiomer of L-lysinium(2+)

[Term]
id: CHEBI:32563
name: lysinate
def: "An α-amino-acid anion that is the conjugate base of lysine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:25094 ! is deprotonated form of lysine

[Term]
id: CHEBI:32564
name: lysinium(1+)
def: "An α-amino-acid cation that is the conjugate acid of lysine, having two cationic amino groups and an anionic carboxy group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018033 CHEBI:32565 ! is deprotonated form of lysinium(2+)
relationship: RO:0018034 CHEBI:25094 ! is protonated form of lysine

[Term]
id: CHEBI:32565
name: lysinium(2+)
def: "An α-amino-acid cation obtained by protonation of both amino groups of lysine." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:32564 ! is protonated form of lysinium(1+)

[Term]
id: CHEBI:32588
name: potassium chloride
def: "A metal chloride salt with a K(+) counterion." []
is_a: CHEBI:190303 ! inorganic potassium salt
is_a: CHEBI:36093 ! inorganic chloride
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50503 ! has role laxative

[Term]
id: CHEBI:3259
name: CCCP
def: "A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:38532 ! hydrazone
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:24869 ! has role ionophore
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0018038 CHEBI:33189 ! has functional parent hydrazonomalononitrile

[Term]
id: CHEBI:32594
name: barium atom
is_a: CHEBI:22313 ! alkaline earth metal atom
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:32600
name: tetracene
def: "An acene that consists of four <em>ortho</em>-fused benzene rings in a rectilinear arrangement." []
is_a: CHEBI:35297 ! acene
is_a: CHEBI:51270 ! tetracenes

[Term]
id: CHEBI:32612
name: isoleucinate
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:24898 ! is deprotonated form of isoleucine

[Term]
id: CHEBI:32613
name: isoleucinium
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:24898 ! is protonated form of isoleucine

[Term]
id: CHEBI:32619
name: L-leucinate
def: "The <small>L</small>-enantiomer of leucinate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32627 ! leucinate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:15603 ! is deprotonated form of L-leucine
relationship: RO:0018039 CHEBI:32623 ! is enantiomer of D-leucinate

[Term]
id: CHEBI:32620
name: L-leucinium
def: "The <small>L</small>-enantiomer of leucinium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32628 ! leucinium
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:15603 ! is protonated form of L-leucine
relationship: RO:0018039 CHEBI:32624 ! is enantiomer of D-leucinium

[Term]
id: CHEBI:32623
name: D-leucinate
def: "The <small>D</small>-enantiomer of leucinate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32627 ! leucinate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:28225 ! is deprotonated form of D-leucine
relationship: RO:0018039 CHEBI:32619 ! is enantiomer of L-leucinate

[Term]
id: CHEBI:32624
name: D-leucinium
def: "The <small>D</small>-enantiomer of leucinium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32628 ! leucinium
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018034 CHEBI:28225 ! is protonated form of D-leucine
relationship: RO:0018039 CHEBI:32620 ! is enantiomer of L-leucinium

[Term]
id: CHEBI:326268
name: 1,4-butanediammonium
def: "An alkane-α,ω-diammonium(2+) that is the dication of putrescine (1,4-butanediamine) arising from protonation of both primary amino groups; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:70977 ! alkane-alpha,omega-diammonium(2+)
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:17148 ! is protonated form of putrescine

[Term]
id: CHEBI:32627
name: leucinate
def: "An α-amino-acid anion that is the conjugate base of leucine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
is_a: CHEBI:63471 ! branched-chain amino-acid anion
relationship: RO:0018033 CHEBI:25017 ! is deprotonated form of leucine

[Term]
id: CHEBI:32628
name: leucinium
def: "An α-amino-acid cation that is the conjugate acid of leucine, arising from protonation of the amino group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:25017 ! is protonated form of leucine

[Term]
id: CHEBI:32644
name: methioninate
def: "A sulfur-containing amino-acid anion that is the conjugate base of methionine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
is_a: CHEBI:63470 ! sulfur-containing amino-acid anion
relationship: RO:0018033 CHEBI:16811 ! is deprotonated form of methionine

[Term]
id: CHEBI:32646
name: methioninium
def: "A sulfur-containing amino-acid cation that is the conjugate acid of methionine, arising from protonation of the amino group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:16811 ! is protonated form of methionine

[Term]
id: CHEBI:32650
name: L-asparaginate
def: "An optically active form of asparaginate having <small>L</small>-configuration." []
is_a: CHEBI:32660 ! asparaginate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:17196 ! is deprotonated form of L-asparagine
relationship: RO:0018039 CHEBI:32656 ! is enantiomer of D-asparaginate

[Term]
id: CHEBI:32651
name: L-asparaginium
is_a: CHEBI:32661 ! asparaginium
relationship: RO:0018034 CHEBI:17196 ! is protonated form of L-asparagine
relationship: RO:0018039 CHEBI:32657 ! is enantiomer of D-asparaginium

[Term]
id: CHEBI:32656
name: D-asparaginate
is_a: CHEBI:32660 ! asparaginate
relationship: RO:0018033 CHEBI:28159 ! is deprotonated form of D-asparagine
relationship: RO:0018039 CHEBI:32650 ! is enantiomer of L-asparaginate

[Term]
id: CHEBI:32657
name: D-asparaginium
is_a: CHEBI:32661 ! asparaginium
relationship: RO:0018034 CHEBI:28159 ! is protonated form of D-asparagine
relationship: RO:0018039 CHEBI:32651 ! is enantiomer of L-asparaginium

[Term]
id: CHEBI:32660
name: asparaginate
def: "An α-amino-acid anion that is the conjugate base of asparagine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:22653 ! is deprotonated form of asparagine

[Term]
id: CHEBI:32661
name: asparaginium
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:22653 ! is protonated form of asparagine

[Term]
id: CHEBI:32665
name: L-glutaminate
def: "An optically active form of glutaminate having <small>L</small>-configuration." []
is_a: CHEBI:32678 ! glutaminate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:18050 ! is deprotonated form of L-glutamine
relationship: RO:0018039 CHEBI:32672 ! is enantiomer of D-glutaminate

[Term]
id: CHEBI:32666
name: L-glutaminium
def: "An optically active form of glutaminium having <small>L</small>-configuration." []
is_a: CHEBI:32679 ! glutaminium
relationship: RO:0018034 CHEBI:18050 ! is protonated form of L-glutamine
relationship: RO:0018039 CHEBI:32673 ! is enantiomer of D-glutaminium

[Term]
id: CHEBI:32672
name: D-glutaminate
def: "An optically active form of glutaminate having <small>D</small>-configuration." []
is_a: CHEBI:32678 ! glutaminate
relationship: RO:0018033 CHEBI:17061 ! is deprotonated form of D-glutamine
relationship: RO:0018039 CHEBI:32665 ! is enantiomer of L-glutaminate

[Term]
id: CHEBI:32673
name: D-glutaminium
def: "An optically active form of glutaminium having <small>D</small>-configuration." []
is_a: CHEBI:32679 ! glutaminium
relationship: RO:0018034 CHEBI:17061 ! is protonated form of D-glutamine
relationship: RO:0018039 CHEBI:32666 ! is enantiomer of L-glutaminium

[Term]
id: CHEBI:32678
name: glutaminate
def: "An α-amino-acid anion that is the conjugate base of glutamine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:28300 ! is deprotonated form of glutamine

[Term]
id: CHEBI:32679
name: glutaminium
def: "An α-amino-acid cation that is the conjugate acid of glutamine, arising from protonation of the amino group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:28300 ! is protonated form of glutamine

[Term]
id: CHEBI:32681
name: L-argininate
def: "An <small>L</small>-α-amino acid anion that is the conjugate base of <small>L</small>-arginine; obtained by deprotonation of the carboxy group." []
is_a: CHEBI:32695 ! argininate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:16467 ! is deprotonated form of L-arginine
relationship: RO:0018039 CHEBI:32688 ! is enantiomer of D-argininate

[Term]
id: CHEBI:32682
name: L-argininium(1+)
def: "The <small>L</small>-enantiomer of argininium(1+)." []
synonym: "L-arginine" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32696 ! argininium(1+)
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32683 ! is deprotonated form of L-argininium(2+)
relationship: RO:0018034 CHEBI:16467 ! is protonated form of L-arginine
relationship: RO:0018039 CHEBI:32689 ! is enantiomer of D-argininium(1+)

[Term]
id: CHEBI:32683
name: L-argininium(2+)
is_a: CHEBI:32697 ! argininium(2+)
relationship: RO:0018034 CHEBI:32682 ! is protonated form of L-argininium(1+)
relationship: RO:0018039 CHEBI:32690 ! is enantiomer of D-argininium(2+)

[Term]
id: CHEBI:32687
name: piperonyl butoxide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38298 ! benzodioxoles
relationship: RO:0000087 CHEBI:25943 ! has role pesticide synergist

[Term]
id: CHEBI:32688
name: D-argininate
is_a: CHEBI:32695 ! argininate
relationship: RO:0018033 CHEBI:15816 ! is deprotonated form of D-arginine
relationship: RO:0018039 CHEBI:32681 ! is enantiomer of L-argininate

[Term]
id: CHEBI:32689
name: D-argininium(1+)
def: "The <small>D</small>-enantiomer of argininium(1+)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32696 ! argininium(1+)
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32690 ! is deprotonated form of D-argininium(2+)
relationship: RO:0018034 CHEBI:15816 ! is protonated form of D-arginine
relationship: RO:0018039 CHEBI:32682 ! is enantiomer of L-argininium(1+)

[Term]
id: CHEBI:32690
name: D-argininium(2+)
is_a: CHEBI:32697 ! argininium(2+)
relationship: RO:0018034 CHEBI:32689 ! is protonated form of D-argininium(1+)
relationship: RO:0018039 CHEBI:32683 ! is enantiomer of L-argininium(2+)

[Term]
id: CHEBI:32695
name: argininate
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:29016 ! is deprotonated form of arginine

[Term]
id: CHEBI:32696
name: argininium(1+)
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018033 CHEBI:32697 ! is deprotonated form of argininium(2+)
relationship: RO:0018034 CHEBI:29016 ! is protonated form of arginine

[Term]
id: CHEBI:32697
name: argininium(2+)
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:32696 ! is protonated form of argininium(1+)

[Term]
id: CHEBI:32727
name: tryptophanate
def: "An α-amino-acid anion that is the conjugate base of tryptophan, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:27897 ! is deprotonated form of tryptophan

[Term]
id: CHEBI:32728
name: tryptophanium
def: "An α-amino-acid cation that is the conjugate acid of tryptophan, arising from protonation of the α-amino group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:27897 ! is protonated form of tryptophan

[Term]
id: CHEBI:32752
name: selenocysteinate(1-)
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:9093 ! is deprotonated form of selenocysteine
relationship: RO:0018034 CHEBI:32753 ! is protonated form of selenocysteinate(2-)

[Term]
id: CHEBI:32753
name: selenocysteinate(2-)
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:32752 ! is deprotonated form of selenocysteinate(1-)

[Term]
id: CHEBI:32754
name: selenocysteinium
def: "An α-amino-acid cation resulting from the protonation of the amino group of selenocysteine." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:9093 ! is protonated form of selenocysteine

[Term]
id: CHEBI:32760
name: L-tyrosinate(1-)
def: "An optically active form of tyrosinate having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32784 ! tyrosinate(1-)
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:17895 ! is deprotonated form of L-tyrosine
relationship: RO:0018033 CHEBI:58315 ! is deprotonated form of L-tyrosine zwitterion
relationship: RO:0018034 CHEBI:32761 ! is protonated form of L-tyrosinate(2-)
relationship: RO:0018039 CHEBI:32773 ! is enantiomer of D-tyrosinate(1-)

[Term]
id: CHEBI:32761
name: L-tyrosinate(2-)
def: "The <small>L</small>-enantiomer of tyrosinate(2−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32785 ! tyrosinate(2-)
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:32760 ! is deprotonated form of L-tyrosinate(1-)
relationship: RO:0018039 CHEBI:32774 ! is enantiomer of D-tyrosinate(2-)

[Term]
id: CHEBI:32762
name: L-tyrosinium
def: "An optically active form of tyrosinium having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32786 ! tyrosinium
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:17895 ! is protonated form of L-tyrosine
relationship: RO:0018034 CHEBI:58315 ! is protonated form of L-tyrosine zwitterion
relationship: RO:0018039 CHEBI:32775 ! is enantiomer of D-tyrosinium

[Term]
id: CHEBI:32773
name: D-tyrosinate(1-)
def: "An optically active form of tyrosinate(1−) having <small>D</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32784 ! tyrosinate(1-)
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:28479 ! is deprotonated form of D-tyrosine
relationship: RO:0018034 CHEBI:32774 ! is protonated form of D-tyrosinate(2-)
relationship: RO:0018039 CHEBI:32760 ! is enantiomer of L-tyrosinate(1-)

[Term]
id: CHEBI:32774
name: D-tyrosinate(2-)
def: "The <small>D</small>-enantiomer of tyrosinate(2−)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32785 ! tyrosinate(2-)
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:32773 ! is deprotonated form of D-tyrosinate(1-)
relationship: RO:0018039 CHEBI:32761 ! is enantiomer of L-tyrosinate(2-)

[Term]
id: CHEBI:32775
name: D-tyrosinium
def: "An optically active form of tyrosinium having <small>D</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32786 ! tyrosinium
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:28479 ! is protonated form of D-tyrosine
relationship: RO:0018039 CHEBI:32762 ! is enantiomer of L-tyrosinium

[Term]
id: CHEBI:32784
name: tyrosinate(1-)
def: "An α-amino-acid anion that is the conjugate base of tyrosine, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:18186 ! is deprotonated form of tyrosine
relationship: RO:0018034 CHEBI:32785 ! is protonated form of tyrosinate(2-)

[Term]
id: CHEBI:32785
name: tyrosinate(2-)
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:32784 ! is deprotonated form of tyrosinate(1-)

[Term]
id: CHEBI:32786
name: tyrosinium
def: "An α-amino-acid cation that is the conjugate acid of tyrosine, arising from protonation of the amino group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:18186 ! is protonated form of tyrosine

[Term]
id: CHEBI:32807
name: o-orsellinic acid
def: "A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group." []
synonym: "2,4-Dihydroxy-6-methylbenzoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23778 ! dihydroxybenzoic acid
is_a: CHEBI:33572 ! resorcinols
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0018034 CHEBI:16162 ! is protonated form of o-orsellinate

[Term]
id: CHEBI:32816
name: pyruvic acid
def: "A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis." []
synonym: "2-Oxopropanoic acid" EXACT [KEGG_COMPOUND]
synonym: "2-oxopropanoic acid" EXACT [ChEBI]
is_a: CHEBI:35910 ! 2-oxo monocarboxylic acid
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:15361 ! is protonated form of pyruvate
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:32820
name: L-threoninate
def: "An <small>L</small>-alpha-amino acid anion that is the conjugate base of <small>L</small>-threonine, arising from deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32832 ! threoninate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018033 CHEBI:16857 ! is deprotonated form of L-threonine
relationship: RO:0018039 CHEBI:32827 ! is enantiomer of D-threoninate

[Term]
id: CHEBI:32822
name: L-threoninium
def: "The <small>L</small>-enantiomer of threoninium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32833 ! threoninium
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:16857 ! is protonated form of L-threonine
relationship: RO:0018039 CHEBI:32828 ! is enantiomer of D-threoninium

[Term]
id: CHEBI:32827
name: D-threoninate
def: "The <small>D</small>-enantiomer of threoninate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32832 ! threoninate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:16398 ! is deprotonated form of D-threonine
relationship: RO:0018039 CHEBI:32820 ! is enantiomer of L-threoninate

[Term]
id: CHEBI:32828
name: D-threoninium
def: "The <small>D</small>-enantiomer of threoninium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32833 ! threoninium
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018034 CHEBI:16398 ! is protonated form of D-threonine
relationship: RO:0018039 CHEBI:32822 ! is enantiomer of L-threoninium

[Term]
id: CHEBI:32832
name: threoninate
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:26986 ! is deprotonated form of threonine

[Term]
id: CHEBI:32833
name: threoninium
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:26986 ! is protonated form of threonine

[Term]
id: CHEBI:32836
name: L-serinate
def: "A serinate that is the conjugate base of <small>L</small>-serine, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:32845 ! serinate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:17115 ! is deprotonated form of L-serine
relationship: RO:0018039 CHEBI:32840 ! is enantiomer of D-serinate

[Term]
id: CHEBI:32837
name: L-serinium
def: "A serinium that is the conjugate acid of <small>L</small>-serine, obtained by protonation of the amino group." []
is_a: CHEBI:32846 ! serinium
relationship: RO:0018034 CHEBI:17115 ! is protonated form of L-serine
relationship: RO:0018039 CHEBI:32841 ! is enantiomer of D-serinium

[Term]
id: CHEBI:32840
name: D-serinate
def: "The <small>D</small>-enantiomer of serinate." []
is_a: CHEBI:32845 ! serinate
relationship: RO:0018033 CHEBI:16523 ! is deprotonated form of D-serine
relationship: RO:0018039 CHEBI:32836 ! is enantiomer of L-serinate

[Term]
id: CHEBI:32841
name: D-serinium
def: "The <small>D</small>-enantiomer of serinium." []
is_a: CHEBI:32846 ! serinium
relationship: RO:0018034 CHEBI:16523 ! is protonated form of D-serine
relationship: RO:0018039 CHEBI:32837 ! is enantiomer of L-serinium

[Term]
id: CHEBI:32845
name: serinate
def: "An α-amino-acid anion that is the conjugate base of serine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:17822 ! is deprotonated form of serine

[Term]
id: CHEBI:32846
name: serinium
def: "An α-amino-acid cation that is the conjugate acid of serine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:17822 ! is protonated form of serine

[Term]
id: CHEBI:32851
name: L-valinate
def: "The <small>L</small>-enantiomer of valinate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32859 ! valinate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:16414 ! is deprotonated form of L-valine
relationship: RO:0018039 CHEBI:32855 ! is enantiomer of D-valinate

[Term]
id: CHEBI:32852
name: L-valinium
def: "The <small>L</small>-enantiomer of  valinium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32860 ! valinium
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:16414 ! is protonated form of L-valine
relationship: RO:0018039 CHEBI:32856 ! is enantiomer of D-valinium

[Term]
id: CHEBI:32855
name: D-valinate
def: "The <small>D</small>-enantiomer of valinate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32859 ! valinate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:27477 ! is deprotonated form of D-valine
relationship: RO:0018039 CHEBI:32851 ! is enantiomer of L-valinate

[Term]
id: CHEBI:32856
name: D-valinium
def: "The <small>D</small>-enantiomer of valinium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32860 ! valinium
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:27477 ! is protonated form of D-valine
relationship: RO:0018039 CHEBI:32852 ! is enantiomer of L-valinium

[Term]
id: CHEBI:32859
name: valinate
is_a: CHEBI:33558 ! alpha-amino-acid anion
is_a: CHEBI:63471 ! branched-chain amino-acid anion
relationship: RO:0018033 CHEBI:27266 ! is deprotonated form of valine

[Term]
id: CHEBI:32860
name: valinium
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:27266 ! is protonated form of valine

[Term]
id: CHEBI:32862
name: L-prolinate
def: "An optically active form of prolinate having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32871 ! prolinate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17203 ! is deprotonated form of L-proline
relationship: RO:0018039 CHEBI:32867 ! is enantiomer of D-prolinate

[Term]
id: CHEBI:32863
name: secondary amine
def: "A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups." []
is_a: CHEBI:32952 ! amine
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0018033 CHEBI:137419 ! is deprotonated form of secondary ammonium ion

[Term]
id: CHEBI:32864
name: L-prolinium
def: "An optically active form of prolinium having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32872 ! prolinium
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17203 ! is protonated form of L-proline
relationship: RO:0018039 CHEBI:32868 ! is enantiomer of D-prolinium

[Term]
id: CHEBI:32867
name: D-prolinate
def: "An optically active form of prolinate having <small>D</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32871 ! prolinate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16313 ! is deprotonated form of D-proline
relationship: RO:0018039 CHEBI:32862 ! is enantiomer of L-prolinate

[Term]
id: CHEBI:32868
name: D-prolinium
def: "An optically active form of prolinium having <small>D</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32872 ! prolinium
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16313 ! is protonated form of D-proline
relationship: RO:0018039 CHEBI:32864 ! is enantiomer of L-prolinium

[Term]
id: CHEBI:32871
name: prolinate
def: "An α-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:26271 ! is deprotonated form of proline

[Term]
id: CHEBI:32872
name: prolinium
def: "An α-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:26271 ! is protonated form of proline

[Term]
id: CHEBI:32876
name: tertiary amine
def: "A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups." []
is_a: CHEBI:32952 ! amine
is_a: CHEBI:50996 ! tertiary amino compound

[Term]
id: CHEBI:32877
name: primary amine
def: "A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group." []
is_a: CHEBI:32952 ! amine
is_a: CHEBI:50994 ! primary amino compound

[Term]
id: CHEBI:32878
name: alkene
def: "An acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula C<small><sub><em>n</em></sub></small>H<small><sub>2<em>n</em></sub></small>. Acyclic branched or unbranched hydrocarbons having more than one double bond are alkadienes, alkatrienes, etc." []
synonym: "olefin" EXACT [ChEBI]
is_a: CHEBI:33645 ! acyclic olefin

[Term]
id: CHEBI:32879
name: propane
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:78017 ! has role food propellant

[Term]
id: CHEBI:32881
name: pentan-3-yl group
is_a: CHEBI:22323 ! alkyl group
relationship: RO:0018037 CHEBI:37830 ! is substitutent group from pentane

[Term]
id: CHEBI:32888
name: gamma-hexachlorocyclohexane
synonym: "1,2,3,4,5,6-Hexachlorocyclohexane" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23457 ! cyclodiene organochlorine insecticide
is_a: CHEBI:24536 ! hexachlorocyclohexane
is_a: CHEBI:33654 ! alicyclic compound
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33288 ! has role rodenticide
relationship: RO:0000087 CHEBI:38706 ! has role pediculicide
relationship: RO:0000087 CHEBI:38956 ! has role ectoparasiticide
relationship: RO:0000087 CHEBI:38999 ! has role GABA-gated chloride channel antagonist
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:32892
name: nonane
def: "A straight chain alkane composed of 9 carbon atoms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component

[Term]
id: CHEBI:32898
name: baccatin III
def: "A tetracyclic diterpenoid isolated from plant species of the genus <em>Taxus</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36054 ! benzoate ester
is_a: CHEBI:47622 ! acetate ester
is_a: CHEBI:52557 ! tetracyclic diterpenoid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018040 CHEBI:36064 ! has parent hydride taxane

[Term]
id: CHEBI:32918
name: 1-naphthaleneacetic acid
def: "A naphthylacetic acid substituted by a carboxymethyl group at position 1." []
is_a: CHEBI:35629 ! naphthylacetic acid
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0018034 CHEBI:156230 ! is protonated form of 1-naphthaleneacetate

[Term]
id: CHEBI:32926
name: octadecane
def: "A straight-chain alkane carrying 18 carbon atoms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:83563 ! long-chain alkane
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:32952
name: amine
def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." []
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:32954
name: sodium acetate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:59230 ! acetate salt
relationship: BFO:0000051 CHEBI:30089 ! has part acetate
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:32955
name: epoxide
def: "Any cyclic ether in which the oxygen atom forms part of a 3-membered ring." []
is_a: CHEBI:37407 ! cyclic ether
relationship: RO:0018040 CHEBI:27561 ! has parent hydride oxirane

[Term]
id: CHEBI:32957
name: lysophosphatidic acids
def: "Any monoacylglycerol phosphate obtained by hydrolytic removal of one of the two acyl groups of any phosphatidic acid or derivatives therein." []
is_a: CHEBI:16961 ! monoacylglycerol phosphate

[Term]
id: CHEBI:32964
name: ornithinate
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:18257 ! is deprotonated form of ornithine
relationship: RO:0018038 CHEBI:31011 ! has functional parent valerate

[Term]
id: CHEBI:32970
name: 2-aminoethanesulfonate
def: "A 1,1-diunsubstituted alkanesulfonate that is ethanesulfonate substituted by an amino group at position 2." []
is_a: CHEBI:62081 ! 1,1-diunsubstituted alkanesulfonate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15891 ! is deprotonated form of taurine

[Term]
id: CHEBI:32988
name: amide
def: "An amide is a derivative of an oxoacid R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> ≠ 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." []
synonym: "Amide" EXACT [KEGG_COMPOUND]
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:33017
name: diphosphate(1-)
def: "A monovalent inorganic anion obtained by deprotonation of one of the phosphate OH groups in diphosphoric acid." []
is_a: CHEBI:35782 ! diphosphate ion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:29888 ! is deprotonated form of diphosphoric acid
relationship: RO:0018034 CHEBI:45212 ! is protonated form of diphosphate(2-)

[Term]
id: CHEBI:33019
name: diphosphate(3-)
def: "A trivalent inorganic anion obtained by removal of all three protons from diphosphoric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35782 ! diphosphate ion
is_a: CHEBI:79387 ! trivalent inorganic anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:45212 ! is deprotonated form of diphosphate(2-)
relationship: RO:0018034 CHEBI:18361 ! is protonated form of diphosphate(4-)

[Term]
id: CHEBI:33038
name: chromyl dichloride
is_a: CHEBI:35403 ! chromium coordination entity
relationship: RO:0018038 CHEBI:33143 ! has functional parent chromic acid

[Term]
id: CHEBI:33070
name: indole-3-butyric acid
def: "A indol-3-yl carboxylic acid that is butanoic acid carrying a 1<em>H</em>-indol-3-yl substituent at position 1." []
is_a: CHEBI:24810 ! indol-3-yl carboxylic acid
relationship: RO:0000087 CHEBI:22676 ! has role auxin
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:143274 ! is protonated form of indole-3-butyrate
relationship: RO:0018038 CHEBI:30772 ! has functional parent butyric acid

[Term]
id: CHEBI:33093
name: boron trifluoride
is_a: CHEBI:38901 ! boron fluoride

[Term]
id: CHEBI:33098
name: 2-nitrotoluene
def: "A mononitrotoluene that is toluene carrying a nitro substituent at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:63171 ! mononitrotoluene
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:33101
name: nitrogen dioxide
synonym: "NITROGEN DIOXIDE" EXACT [PDBeChem]
is_a: CHEBI:35196 ! nitrogen oxide

[Term]
id: CHEBI:3311
name: calcium carbonate
def: "A calcium salt with formula CCaO<small><sub>3</sub></small>." []
is_a: CHEBI:190295 ! inorganic calcium salt
is_a: CHEBI:35156 ! calcium salt
is_a: CHEBI:46721 ! carbonate salt
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65265 ! has role antacid
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77182 ! has role food colouring
relationship: RO:0000087 CHEBI:77960 ! has role food firming agent

[Term]
id: CHEBI:33127
name: sulfadiazinate
is_a: CHEBI:50335 ! organic nitrogen anion
relationship: RO:0018033 CHEBI:9328 ! is deprotonated form of sulfadiazine

[Term]
id: CHEBI:33135
name: pyrrolidine
def: "A cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family." []
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:37949 ! azacycloalkane
is_a: CHEBI:38260 ! pyrrolidines
relationship: RO:0018033 CHEBI:52145 ! is deprotonated form of pyrrolidinium ion

[Term]
id: CHEBI:33140
name: pyrazolium
is_a: CHEBI:38179 ! monocyclic heteroarene
relationship: RO:0018034 CHEBI:17241 ! is protonated form of 1H-pyrazole

[Term]
id: CHEBI:33143
name: chromic acid
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35401 ! chromium oxoacid
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent
relationship: RO:0018034 CHEBI:33144 ! is protonated form of hydrogenchromate

[Term]
id: CHEBI:33144
name: hydrogenchromate
def: "A monovalent inorganic anion obtained by deprotonation of one of the two OH groups in chromic acid." []
is_a: CHEBI:35402 ! chromium oxoanion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:33143 ! is deprotonated form of chromic acid
relationship: RO:0018034 CHEBI:35404 ! is protonated form of chromate(2-)

[Term]
id: CHEBI:33145
name: boron oxoacid
is_a: CHEBI:22916 ! boron molecular entity
is_a: CHEBI:24833 ! oxoacid

[Term]
id: CHEBI:33173
name: benzimidazolide
is_a: CHEBI:50335 ! organic nitrogen anion
relationship: RO:0018033 CHEBI:41275 ! is deprotonated form of 1H-benzimidazole

[Term]
id: CHEBI:33186
name: malononitrile
def: "A dinitrile that is methane substituted by two cyano groups." []
is_a: CHEBI:51308 ! dinitrile
is_a: CHEBI:80291 ! aliphatic nitrile

[Term]
id: CHEBI:33187
name: oxomalononitrile
is_a: CHEBI:51852 ! alpha-ketonitrile
relationship: RO:0018038 CHEBI:33186 ! has functional parent malononitrile

[Term]
id: CHEBI:33189
name: hydrazonomalononitrile
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:38532 ! hydrazone
relationship: RO:0018038 CHEBI:33187 ! has functional parent oxomalononitrile

[Term]
id: CHEBI:33202
name: 2-thiobarbituric acid
def: "A barbiturate, the structure of which is that of barbituric acid in which the oxygen at C-2 is replaced by sulfur." []
is_a: CHEBI:22693 ! barbiturates
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:33216
name: bisphenol A
def: "A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22901 ! bisphenol
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:76988 ! has role xenoestrogen
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:33217
name: 3,3',5,5'-tetrabromobisphenol A
def: "A bromobisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups and the phenyl rings are substituted by bromo groups at positions 2, 2', 6 and 6'. It is a brominated flame retardant." []
is_a: CHEBI:172368 ! brominated flame retardant
is_a: CHEBI:22931 ! bromobisphenol
relationship: RO:0018038 CHEBI:33216 ! has functional parent bisphenol A

[Term]
id: CHEBI:33224
name: chromane
def: "A benzopyran consisting of a pyran ring having a benzene ring <em>ortho</em>-fused across positions 2 and 3." []
is_a: CHEBI:23230 ! chromanes

[Term]
id: CHEBI:33229
name: vitamin (role)
def: "A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term \"vitamines\" (from <em>vita</em> + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines." []
is_a: CHEBI:27027 ! micronutrient
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:33231
name: antitubercular agent
def: "A substance that kills or slows the growth of <em>Mycobacterium tuberculosis</em> and is used in the treatment of tuberculosis." []
is_a: CHEBI:64912 ! antimycobacterial drug

[Term]
id: CHEBI:33232
name: application
def: "Intended use of the molecular entity or part thereof by humans." []
is_a: CHEBI:50906 ! role

[Term]
id: CHEBI:33233
name: fundamental particle
def: "A particle not known to have substructure." []
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:33234
name: vitamin E
def: "Any member of a group of fat-soluble chromanols  that exhibit biological activity against vitamin E deficiency. The vitamers in this class consists of a chroman-6-ol core which is substituted at position 2 by a methyl group and (also at position 2) either a saturated or a triply-unsaturated hydrocarbon chain consisting of three isoprenoid units. The major function of vitamin E is to act as a natural antioxidant by scavenging free radicals and molecular oxygen." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23229 ! chromanol
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:24020 ! has role fat-soluble vitamin (role)
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:78631 ! has functional parent chroman-6-ol

[Term]
id: CHEBI:33238
name: monoatomic entity
def: "A monoatomic entity is a molecular entity consisting of a single atom." []
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:33240
name: coordination entity
def: "An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands)." []
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:33241
name: oxoacid derivative
is_a: CHEBI:37577 ! heteroatomic molecular entity
relationship: RO:0018038 CHEBI:24833 ! has functional parent oxoacid

[Term]
id: CHEBI:33242
name: inorganic hydride
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:33692 ! hydrides

[Term]
id: CHEBI:33245
name: organic fundamental parent
def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." []
is_a: CHEBI:37175 ! organic hydride
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33246
name: inorganic group
def: "Any substituent group which does not contain carbon." []
is_a: CHEBI:24433 ! group

[Term]
id: CHEBI:33247
name: organic group
def: "Any substituent group or skeleton containing carbon." []
is_a: CHEBI:24433 ! group
relationship: RO:0018033 CHEBI:64769 ! is deprotonated form of organic cationic group
relationship: RO:0018034 CHEBI:64775 ! is protonated form of organic anionic group

[Term]
id: CHEBI:33248
name: hydrocarbyl group
def: "A univalent group formed by removing a hydrogen atom from a hydrocarbon." []
is_a: CHEBI:33249 ! organyl group
relationship: RO:0018037 CHEBI:24632 ! is substitutent group from hydrocarbon

[Term]
id: CHEBI:33249
name: organyl group
def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." []
is_a: CHEBI:51447 ! organic univalent group

[Term]
id: CHEBI:33250
name: atom
def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." []
is_a: CHEBI:24431 ! chemical entity
relationship: BFO:0000051 CHEBI:10545 ! has part electron
relationship: BFO:0000051 CHEBI:33252 ! has part atomic nucleus

[Term]
id: CHEBI:33251
name: monoatomic hydrogen
is_a: CHEBI:33238 ! monoatomic entity
is_a: CHEBI:33260 ! elemental hydrogen

[Term]
id: CHEBI:33252
name: atomic nucleus
def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." []
is_a: CHEBI:36347 ! nuclear particle
relationship: BFO:0000051 CHEBI:33253 ! has part nucleon

[Term]
id: CHEBI:33253
name: nucleon
def: "Heavy nuclear particle: proton or neutron." []
is_a: CHEBI:36339 ! baryon
is_a: CHEBI:36347 ! nuclear particle

[Term]
id: CHEBI:33255
name: alkylmercury compound
is_a: CHEBI:25706 ! organomercury compound

[Term]
id: CHEBI:33256
name: primary amide
def: "A derivative of an oxoacid R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> ≠ 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." []
is_a: CHEBI:32988 ! amide

[Term]
id: CHEBI:33257
name: secondary amide
def: "A derivative of two oxoacids R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> ≠ 0) in which two acyl groups are attached to the amino or substituted amino group." []
is_a: CHEBI:32988 ! amide

[Term]
id: CHEBI:33259
name: elemental molecular entity
def: "A molecular entity all atoms of which have the same atomic number." []
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:33260
name: elemental hydrogen
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:33259 ! elemental molecular entity
is_a: CHEBI:33608 ! hydrogen molecular entity

[Term]
id: CHEBI:33261
name: organosulfur compound
def: "An organosulfur compound is a compound containing at least one carbon-sulfur bond." []
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:36962 ! organochalcogen compound

[Term]
id: CHEBI:33262
name: elemental oxygen
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:33263
name: diatomic oxygen
is_a: CHEBI:33262 ! elemental oxygen

[Term]
id: CHEBI:33265
name: triatomic oxygen
is_a: CHEBI:33262 ! elemental oxygen

[Term]
id: CHEBI:33266
name: diatomic nitrogen
is_a: CHEBI:33267 ! elemental nitrogen

[Term]
id: CHEBI:33267
name: elemental nitrogen
is_a: CHEBI:33465 ! elemental pnictogen
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:33273
name: polyatomic anion
def: "An anion consisting of more than one atom." []
is_a: CHEBI:22563 ! anion
is_a: CHEBI:36358 ! polyatomic ion

[Term]
id: CHEBI:33280
name: molecular messenger
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:33281
name: antimicrobial agent
def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:33282
name: antibacterial agent
def: "A substance (or active part thereof) that kills or slows the growth of bacteria." []
is_a: CHEBI:33281 ! antimicrobial agent

[Term]
id: CHEBI:33284
name: nutrient
def: "A nutrient is a food component that an organism uses to survive and grow." []
is_a: CHEBI:78295 ! food component

[Term]
id: CHEBI:33285
name: heteroorganic entity
def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33286
name: agrochemical
def: "An agrochemical is a substance that is used in agriculture or horticulture." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:33287
name: fertilizer
def: "A fertilizer is any substance that is added to soil or water to assist the growth of plants." []
is_a: CHEBI:33286 ! agrochemical

[Term]
id: CHEBI:33288
name: rodenticide
def: "A substance used to destroy rodent pests." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:33289
name: avicide
def: "A substance used to destroy bird pests (class <em>Aves</em>)." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:33290
name: food
def: "A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life." []
is_a: CHEBI:52211 ! physiological role
relationship: BFO:0000051 CHEBI:78295 ! has part food component

[Term]
id: CHEBI:33292
name: fuel
def: "An energy-rich substance that can be transformed with release of usable energy." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:33295
name: diagnostic agent
def: "A substance administered to aid diagnosis of a disease." []
is_a: CHEBI:52217 ! pharmaceutical

[Term]
id: CHEBI:33296
name: alkali metal molecular entity
def: "A molecular entity containing one or more atoms of an alkali metal." []
is_a: CHEBI:33674 ! s-block molecular entity
relationship: BFO:0000051 CHEBI:22314 ! has part alkali metal atom

[Term]
id: CHEBI:33298
name: lithium molecular entity
is_a: CHEBI:33296 ! alkali metal molecular entity
relationship: BFO:0000051 CHEBI:30145 ! has part lithium atom

[Term]
id: CHEBI:33299
name: alkaline earth molecular entity
def: "An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal." []
is_a: CHEBI:33674 ! s-block molecular entity
relationship: BFO:0000051 CHEBI:22313 ! has part alkaline earth metal atom

[Term]
id: CHEBI:33300
name: pnictogen
def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." []
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33301
name: bismuth atom
is_a: CHEBI:233500 ! post-transition metal atom
is_a: CHEBI:33300 ! pnictogen

[Term]
id: CHEBI:33302
name: pnictogen molecular entity
def: "A p-block molecular entity containing any pnictogen." []
is_a: CHEBI:33675 ! p-block molecular entity
relationship: BFO:0000051 CHEBI:33300 ! has part pnictogen

[Term]
id: CHEBI:33303
name: chalcogen
def: "Any p-block element belonging to the group 16 family of the periodic table." []
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33304
name: chalcogen molecular entity
def: "Any p-block molecular entity containing a chalcogen." []
is_a: CHEBI:33675 ! p-block molecular entity
relationship: BFO:0000051 CHEBI:33303 ! has part chalcogen

[Term]
id: CHEBI:33305
name: tellurium molecular entity
is_a: CHEBI:33304 ! chalcogen molecular entity
relationship: BFO:0000051 CHEBI:30452 ! has part tellurium atom

[Term]
id: CHEBI:33306
name: carbon group element atom
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33307
name: thiocarboxylic acid
def: "An organic acid in which one or both oxygens of a carboxy group have been replaced by divalent sulfur." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:64709 ! organic acid

[Term]
id: CHEBI:33308
name: carboxylic ester
def: "An ester of a carboxylic acid, R<small><sup>1</small></sup>C(=O)OR<small><sup>2</small></sup>, where R<small><sup>1</small></sup> = H or organyl and R<small><sup>2</small></sup> = organyl." []
is_a: CHEBI:35701 ! ester
is_a: CHEBI:36586 ! carbonyl compound

[Term]
id: CHEBI:33309
name: noble gas atom
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33318 ! main group element atom

[Term]
id: CHEBI:33314
name: radon atom
is_a: CHEBI:33309 ! noble gas atom
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33317
name: boron group element atom
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:33318
name: main group element atom
def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." []
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:33319
name: lanthanoid atom
is_a: CHEBI:33321 ! rare earth metal atom

[Term]
id: CHEBI:33320
name: actinoid atom
is_a: CHEBI:33562 ! f-block element atom

[Term]
id: CHEBI:33321
name: rare earth metal atom
is_a: CHEBI:27081 ! transition element atom

[Term]
id: CHEBI:33324
name: strontium atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22313 ! alkaline earth metal atom
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent

[Term]
id: CHEBI:33327
name: silicon oxide
is_a: CHEBI:24836 ! inorganic oxide
is_a: CHEBI:26677 ! silicon molecular entity

[Term]
id: CHEBI:33329
name: silicon hydride
is_a: CHEBI:26677 ! silicon molecular entity
is_a: CHEBI:33242 ! inorganic hydride

[Term]
id: CHEBI:33338
name: aryl group
def: "A group derived from an arene by removal of a hydrogen atom from a ring carbon atom." []
is_a: CHEBI:33248 ! hydrocarbyl group
relationship: RO:0018037 CHEBI:33658 ! is substitutent group from arene

[Term]
id: CHEBI:33340
name: zinc group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33341
name: titanium atom
is_a: CHEBI:33345 ! titanium group element atom

[Term]
id: CHEBI:33342
name: zirconium atom
is_a: CHEBI:33345 ! titanium group element atom

[Term]
id: CHEBI:33343
name: hafnium atom
is_a: CHEBI:33345 ! titanium group element atom

[Term]
id: CHEBI:33345
name: titanium group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33347
name: vanadium group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33348
name: tantalum atom
is_a: CHEBI:33347 ! vanadium group element atom

[Term]
id: CHEBI:33350
name: chromium group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33352
name: manganese group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33353
name: technetium atom
is_a: CHEBI:33352 ! manganese group element atom

[Term]
id: CHEBI:33356
name: iron group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33358
name: cobalt group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33359
name: rhodium atom
def: "A cobalt group element atom of atomic number 45." []
is_a: CHEBI:33358 ! cobalt group element atom

[Term]
id: CHEBI:33362
name: nickel group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33364
name: platinum
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33362 ! nickel group element atom
is_a: CHEBI:33365 ! platinum group metal atom
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:33365
name: platinum group metal atom
is_a: CHEBI:27081 ! transition element atom

[Term]
id: CHEBI:33366
name: copper group element atom
is_a: CHEBI:33561 ! d-block element atom

[Term]
id: CHEBI:33371
name: technetium-99
is_a: CHEBI:33353 ! technetium atom

[Term]
id: CHEBI:33375
name: gadolinium atom
is_a: CHEBI:33319 ! lanthanoid atom
is_a: CHEBI:33562 ! f-block element atom

[Term]
id: CHEBI:33384
name: L-serine zwitterion
def: "A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of <small>L</small>-serine." []
is_a: CHEBI:35243 ! serine zwitterion
is_a: CHEBI:59869 ! L-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:17115 ! is tautomer of L-serine
relationship: RO:0018039 CHEBI:35247 ! is enantiomer of D-serine zwitterion

[Term]
id: CHEBI:33385
name: thorium
is_a: CHEBI:33320 ! actinoid atom

[Term]
id: CHEBI:33402
name: sulfur oxoacid
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:33484 ! chalcogen oxoacid

[Term]
id: CHEBI:33404
name: 3-hydroxypropionic acid
def: "A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group." []
synonym: "3-Hydroxypropanoic acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:194306 ! omega-hydroxy-short-chain fatty acid
is_a: CHEBI:35969 ! 3-hydroxy monocarboxylic acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16510 ! is protonated form of 3-hydroxypropionate
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:33405
name: hydracid
def: "A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33608 ! hydrogen molecular entity
relationship: RO:0000087 CHEBI:39141 ! has role Bronsted acid

[Term]
id: CHEBI:33406
name: organoarsenic compound
is_a: CHEBI:143084 ! organometalloidal compound
is_a: CHEBI:22632 ! arsenic molecular entity

[Term]
id: CHEBI:33407
name: arsenic oxoacid
is_a: CHEBI:22632 ! arsenic molecular entity
is_a: CHEBI:33408 ! pnictogen oxoacid

[Term]
id: CHEBI:33408
name: pnictogen oxoacid
is_a: CHEBI:24833 ! oxoacid
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid

[Term]
id: CHEBI:33409
name: methylarsonate(1-)
is_a: CHEBI:50956 ! organoarsonic acid anion
relationship: RO:0018033 CHEBI:29852 ! is deprotonated form of methylarsonic acid
relationship: RO:0018034 CHEBI:16005 ! is protonated form of methylarsonate(2-)

[Term]
id: CHEBI:33415
name: elemental carbon
is_a: CHEBI:33259 ! elemental molecular entity
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33416
name: fullerene
def: "A compound composed solely of an even number of carbon atoms, which form a cage-like fused-ring polycyclic system with twelve five-membered rings and the rest six-membered rings. The term has been broadened to include any closed cage structure consisting entirely of three-coordinate carbon atoms." []
is_a: CHEBI:33415 ! elemental carbon
is_a: CHEBI:33640 ! polycyclic cage

[Term]
id: CHEBI:33424
name: sulfur oxoacid derivative
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:33241 ! oxoacid derivative

[Term]
id: CHEBI:33425
name: halogen oxoacid
is_a: CHEBI:24471 ! halogen molecular entity
is_a: CHEBI:24833 ! oxoacid
relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid

[Term]
id: CHEBI:33426
name: chlorine oxoacid
is_a: CHEBI:23117 ! chlorine molecular entity
is_a: CHEBI:33425 ! halogen oxoacid
relationship: RO:0018034 CHEBI:33437 ! is protonated form of chlorine oxoanion

[Term]
id: CHEBI:33427
name: bromine oxoacid
is_a: CHEBI:22928 ! bromine molecular entity
is_a: CHEBI:33425 ! halogen oxoacid

[Term]
id: CHEBI:33429
name: monoatomic monoanion
is_a: CHEBI:23905 ! monoatomic anion
is_a: CHEBI:36830 ! monoanion

[Term]
id: CHEBI:33431
name: elemental chlorine
is_a: CHEBI:23117 ! chlorine molecular entity
is_a: CHEBI:33434 ! elemental halogen

[Term]
id: CHEBI:33432
name: monoatomic chlorine
is_a: CHEBI:33431 ! elemental chlorine
is_a: CHEBI:33433 ! monoatomic halogen

[Term]
id: CHEBI:33433
name: monoatomic halogen
is_a: CHEBI:33238 ! monoatomic entity

[Term]
id: CHEBI:33434
name: elemental halogen
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:33437
name: chlorine oxoanion
is_a: CHEBI:23117 ! chlorine molecular entity
is_a: CHEBI:33443 ! halogen oxoanion
relationship: RO:0018033 CHEBI:33426 ! is deprotonated form of chlorine oxoacid

[Term]
id: CHEBI:33443
name: halogen oxoanion
is_a: CHEBI:24471 ! halogen molecular entity
is_a: CHEBI:24834 ! inorganic anion
is_a: CHEBI:35406 ! oxoanion

[Term]
id: CHEBI:33444
name: bromine oxoanion
is_a: CHEBI:22928 ! bromine molecular entity
is_a: CHEBI:33443 ! halogen oxoanion

[Term]
id: CHEBI:33447
name: phospho sugar
def: "Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid." []
is_a: CHEBI:26816 ! carbohydrate phosphate
is_a: CHEBI:63367 ! monosaccharide derivative

[Term]
id: CHEBI:33452
name: benzylic group
def: "Arylmethyl groups and derivatives formed by substitution: ArCR<small><sub>2</sub></small>‒." []
is_a: CHEBI:33249 ! organyl group

[Term]
id: CHEBI:33455
name: nitrogen oxoacid
is_a: CHEBI:33408 ! pnictogen oxoacid
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:33456
name: organoheteryl group
def: "A univalent group containing carbon which has its free valence at an atom other than carbon." []
is_a: CHEBI:51447 ! organic univalent group

[Term]
id: CHEBI:33457
name: phosphorus oxoacid
def: "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." []
is_a: CHEBI:33408 ! pnictogen oxoacid
is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives

[Term]
id: CHEBI:33458
name: nitrogen oxoanion
is_a: CHEBI:33459 ! pnictogen oxoanion
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:33459
name: pnictogen oxoanion
is_a: CHEBI:33302 ! pnictogen molecular entity
is_a: CHEBI:35406 ! oxoanion

[Term]
id: CHEBI:33461
name: phosphorus oxoanion
is_a: CHEBI:24834 ! inorganic anion
is_a: CHEBI:26082 ! phosphorus molecular entity
is_a: CHEBI:33459 ! pnictogen oxoanion

[Term]
id: CHEBI:33462
name: phosphonate(1-)
def: "A monovalent inorganic anion obtained by deprotonation of one of the two OH groups in phosphonic acid." []
is_a: CHEBI:33461 ! phosphorus oxoanion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:44976 ! is deprotonated form of phosphonic acid
relationship: RO:0018034 CHEBI:16215 ! is protonated form of phosphonate(2-)

[Term]
id: CHEBI:33465
name: elemental pnictogen
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:33259 ! elemental molecular entity
is_a: CHEBI:33302 ! pnictogen molecular entity

[Term]
id: CHEBI:3347
name: candesartan
def: "A benzimidazolecarboxylic acid that is 1<em>H</em>-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1<em>H</em>-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension." []
is_a: CHEBI:35688 ! benzimidazolecarboxylic acid
is_a: CHEBI:48420 ! biphenylyltetrazole
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:61016 ! has role angiotensin receptor antagonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:149509 ! is protonated form of candesartan(2-)

[Term]
id: CHEBI:33482
name: sulfur oxoanion
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:33485 ! chalcogen oxoanion

[Term]
id: CHEBI:33484
name: chalcogen oxoacid
is_a: CHEBI:24833 ! oxoacid
relationship: RO:0000087 CHEBI:138103 ! has role inorganic acid

[Term]
id: CHEBI:33485
name: chalcogen oxoanion
is_a: CHEBI:35406 ! oxoanion

[Term]
id: CHEBI:33497
name: transition element molecular entity
def: "A molecular entity containing one or more atoms of a transition element." []
is_a: CHEBI:23367 ! molecular entity
relationship: BFO:0000051 CHEBI:27081 ! has part transition element atom

[Term]
id: CHEBI:33498
name: actinoid molecular entity
is_a: CHEBI:33677 ! f-block molecular entity
relationship: BFO:0000051 CHEBI:33320 ! has part actinoid atom

[Term]
id: CHEBI:33499
name: uranium molecular entity
is_a: CHEBI:33498 ! actinoid molecular entity
relationship: BFO:0000051 CHEBI:27214 ! has part uranium atom

[Term]
id: CHEBI:33504
name: alkali metal cation
is_a: CHEBI:25213 ! metal cation

[Term]
id: CHEBI:33513
name: alkaline earth cation
is_a: CHEBI:25213 ! metal cation
is_a: CHEBI:33299 ! alkaline earth molecular entity

[Term]
id: CHEBI:33515
name: transition element cation
is_a: CHEBI:25213 ! metal cation

[Term]
id: CHEBI:33516
name: chromium cation
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:61310 ! chromium ion

[Term]
id: CHEBI:33521
name: metal atom
def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." []
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:33535
name: sulfur hydride
is_a: CHEBI:26835 ! sulfur molecular entity
is_a: CHEBI:36902 ! chalcogen hydride

[Term]
id: CHEBI:33543
name: sulfonate
def: "The sulfur oxoanion formed by deprotonation of sulfonic acid." []
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: RO:0018033 CHEBI:29214 ! is deprotonated form of sulfonic acid

[Term]
id: CHEBI:33551
name: organosulfonic acid
def: "An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:33552 ! sulfonic acid derivative
is_a: CHEBI:64709 ! organic acid
relationship: BFO:0000051 CHEBI:29922 ! has part sulfo group
relationship: BFO:0000051 CHEBI:33249 ! has part organyl group
relationship: RO:0018034 CHEBI:33554 ! is protonated form of organosulfonate oxoanion

[Term]
id: CHEBI:33552
name: sulfonic acid derivative
is_a: CHEBI:33424 ! sulfur oxoacid derivative
relationship: RO:0018038 CHEBI:29214 ! has functional parent sulfonic acid

[Term]
id: CHEBI:33554
name: organosulfonate oxoanion
def: "An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:33551 ! is deprotonated form of organosulfonic acid
relationship: RO:0018038 CHEBI:33543 ! has functional parent sulfonate

[Term]
id: CHEBI:33555
name: arenesulfonic acid
def: "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an aryl group." []
is_a: CHEBI:33551 ! organosulfonic acid
relationship: BFO:0000051 CHEBI:33338 ! has part aryl group
relationship: RO:0018034 CHEBI:22713 ! is protonated form of arenesulfonate oxoanion

[Term]
id: CHEBI:33557
name: aminobenzenesulfonic acid
def: "Any arenesulfonic acid that is benzenesulfonic acid substituted by at least one amino group at unspecified position." []
is_a: CHEBI:33555 ! arenesulfonic acid
is_a: CHEBI:37793 ! amino sulfonic acid

[Term]
id: CHEBI:33558
name: alpha-amino-acid anion
def: "An amino-acid anion obtained by deprotonation of any α-amino acid." []
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:33704 ! is deprotonated form of alpha-amino acid

[Term]
id: CHEBI:33559
name: s-block element atom
is_a: CHEBI:33250 ! atom

[Term]
id: CHEBI:33560
name: p-block element atom
def: "Any main group element atom belonging to the p-block of the periodic table." []
is_a: CHEBI:33318 ! main group element atom

[Term]
id: CHEBI:33561
name: d-block element atom
is_a: CHEBI:27081 ! transition element atom

[Term]
id: CHEBI:33562
name: f-block element atom
is_a: CHEBI:27081 ! transition element atom

[Term]
id: CHEBI:33563
name: glycolipid
def: "Any member of class of 1,2-di-<em>O</em>-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar part acylated by one or more fatty acids and the glycerol part may be absent." []
is_a: CHEBI:35740 ! liposaccharide

[Term]
id: CHEBI:33566
name: catechols
def: "Any compound containing an <em>o</em>-diphenol component." []
is_a: CHEBI:33570 ! benzenediols

[Term]
id: CHEBI:33567
name: catecholamine
def: "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." []
is_a: CHEBI:25375 ! monoamine molecular messenger
is_a: CHEBI:33566 ! catechols

[Term]
id: CHEBI:33568
name: adrenaline
def: "A racemate comprising equimolar amounts of (<i>R</i>)-adrenaline and (<i>S</i>)-adrenaline." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:28918 ! has part (R)-adrenaline
relationship: BFO:0000051 CHEBI:40751 ! has part (S)-adrenaline
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:33569
name: noradrenaline
def: "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." []
is_a: CHEBI:33567 ! catecholamine
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:166902 ! is deprotonated form of noradrenaline(1+)

[Term]
id: CHEBI:33570
name: benzenediols
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:33572
name: resorcinols
def: "Any benzenediol in which the two hydroxy groups are <em>meta</em> to one another." []
is_a: CHEBI:33570 ! benzenediols

[Term]
id: CHEBI:33575
name: carboxylic acid
def: "A carbon oxoacid acid carrying at least one ‒C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." []
is_a: CHEBI:35605 ! carbon oxoacid
is_a: CHEBI:36586 ! carbonyl compound
is_a: CHEBI:64709 ! organic acid
relationship: BFO:0000051 CHEBI:46883 ! has part carboxy group
relationship: RO:0018034 CHEBI:29067 ! is protonated form of carboxylic acid anion

[Term]
id: CHEBI:33576
name: sulfur-containing carboxylic acid
def: "Any carboxylic acid having a sulfur substituent." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:33575 ! carboxylic acid

[Term]
id: CHEBI:33579
name: main group molecular entity
def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." []
is_a: CHEBI:23367 ! molecular entity
relationship: BFO:0000051 CHEBI:33318 ! has part main group element atom

[Term]
id: CHEBI:33581
name: boron group molecular entity
is_a: CHEBI:33675 ! p-block molecular entity
relationship: BFO:0000051 CHEBI:33317 ! has part boron group element atom

[Term]
id: CHEBI:33582
name: carbon group molecular entity
is_a: CHEBI:33675 ! p-block molecular entity
relationship: BFO:0000051 CHEBI:33306 ! has part carbon group element atom

[Term]
id: CHEBI:33583
name: noble gas molecular entity
def: "A main group molecular entity containing one or more atoms of any noble gas." []
is_a: CHEBI:33579 ! main group molecular entity
relationship: BFO:0000051 CHEBI:33309 ! has part noble gas atom

[Term]
id: CHEBI:33584
name: germanium molecular entity
is_a: CHEBI:33582 ! carbon group molecular entity
relationship: BFO:0000051 CHEBI:30441 ! has part germanium atom

[Term]
id: CHEBI:33585
name: lead molecular entity
is_a: CHEBI:33582 ! carbon group molecular entity
relationship: BFO:0000051 CHEBI:25016 ! has part lead atom

[Term]
id: CHEBI:33586
name: organolead compound
def: "A compound containing at least one carbon-lead bond." []
is_a: CHEBI:25707 ! organometallic compound
is_a: CHEBI:33585 ! lead molecular entity

[Term]
id: CHEBI:33587
name: germanium hydride
is_a: CHEBI:33242 ! inorganic hydride
is_a: CHEBI:33584 ! germanium molecular entity

[Term]
id: CHEBI:33588
name: boron hydride
is_a: CHEBI:22916 ! boron molecular entity
is_a: CHEBI:33242 ! inorganic hydride

[Term]
id: CHEBI:33589
name: boranes
def: "The molecular hydrides of boron." []
is_a: CHEBI:33588 ! boron hydride

[Term]
id: CHEBI:33590
name: diborane(6)
is_a: CHEBI:33734 ! polyboron hydride
is_a: CHEBI:51685 ! diborane

[Term]
id: CHEBI:33595
name: cyclic compound
def: "Any molecule that consists of a series of atoms joined together to form a ring." []
is_a: CHEBI:25367 ! molecule

[Term]
id: CHEBI:33597
name: homocyclic compound
def: "A cyclic compound having as ring members atoms of the same element only." []
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33598
name: carbocyclic compound
def: "A homocyclic compound in which all of the ring members are carbon atoms." []
is_a: CHEBI:33597 ! homocyclic compound
is_a: CHEBI:33832 ! organic cyclic compound

[Term]
id: CHEBI:33599
name: spiro compound
def: "A compound having one atom as the only common member of two rings." []
is_a: CHEBI:33635 ! polycyclic compound

[Term]
id: CHEBI:33608
name: hydrogen molecular entity
is_a: CHEBI:33674 ! s-block molecular entity
relationship: BFO:0000051 CHEBI:49637 ! has part hydrogen atom

[Term]
id: CHEBI:33609
name: elemental boron
is_a: CHEBI:22916 ! boron molecular entity
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:33620
name: aluminium molecular entity
is_a: CHEBI:33581 ! boron group molecular entity
relationship: BFO:0000051 CHEBI:28984 ! has part aluminium atom

[Term]
id: CHEBI:33623
name: aluminium oxides
is_a: CHEBI:133331 ! metal oxide
is_a: CHEBI:33620 ! aluminium molecular entity

[Term]
id: CHEBI:33624
name: bromophenol
def: "A halophenol that is any phenol containing one or more covalently bonded bromine atoms." []
is_a: CHEBI:37149 ! bromobenzenes
is_a: CHEBI:38856 ! halophenol

[Term]
id: CHEBI:33625
name: dibromophenol
def: "A bromophenol that consists of phenol bearing two bromo substituents at unspecified positions." []
is_a: CHEBI:33624 ! bromophenol
relationship: RO:0018038 CHEBI:37147 ! has functional parent dibromobenzene

[Term]
id: CHEBI:33627
name: monoatomic aluminium
is_a: CHEBI:33238 ! monoatomic entity
is_a: CHEBI:33628 ! elemental aluminium

[Term]
id: CHEBI:33628
name: elemental aluminium
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:33259 ! elemental molecular entity
is_a: CHEBI:33620 ! aluminium molecular entity

[Term]
id: CHEBI:33629
name: aluminium(0)
is_a: CHEBI:33628 ! elemental aluminium

[Term]
id: CHEBI:33635
name: polycyclic compound
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33636
name: bicyclic compound
def: "A molecule that features two fused rings." []
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33637
name: ortho-fused compound
def: "A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have <em>n</em> common faces and 2<em>n</em> common atoms." []
is_a: CHEBI:35293 ! fused compound

[Term]
id: CHEBI:33639
name: ortho- and peri-fused compound
def: "A polycyclic compound in which one ring contains two, and only two, atoms in common with each of two or more rings of a contiguous series of rings. Such compounds have <em>n</em> common faces and less than 2<em>n</em> common atoms." []
is_a: CHEBI:35293 ! fused compound

[Term]
id: CHEBI:33640
name: polycyclic cage
def: "A polycyclic compound having the shape of a cage." []
is_a: CHEBI:35990 ! bridged compound

[Term]
id: CHEBI:33641
name: olefin
def: "Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes." []
is_a: CHEBI:24632 ! hydrocarbon
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:33642
name: cyclic olefin
def: "The inclusive term for any cyclic hydrocarbon having any number of double bonds." []
is_a: CHEBI:33641 ! olefin
is_a: CHEBI:33654 ! alicyclic compound

[Term]
id: CHEBI:33643
name: cycloalkene
def: "An unsaturated monocyclic hydrocarbon having at least one endocyclic double bond." []
is_a: CHEBI:33664 ! monocyclic hydrocarbon
is_a: CHEBI:36403 ! monocyclic olefin

[Term]
id: CHEBI:33644
name: acetylenes
def: "Acyclic (branched or unbranched) and cyclic (with or without side chain) hydrocarbons having one or more carbon-carbon triple bonds." []
is_a: CHEBI:24632 ! hydrocarbon
is_a: CHEBI:73474 ! acetylenic compound

[Term]
id: CHEBI:33645
name: acyclic olefin
def: "Acyclic branched or unbranched hydrocarbons having one or more carbon-carbon double bond." []
is_a: CHEBI:33641 ! olefin

[Term]
id: CHEBI:33646
name: alkadiene
def: "Acyclic branched or unbranched hydrocarbons having two carbon-carbon double bonds." []
is_a: CHEBI:33645 ! acyclic olefin

[Term]
id: CHEBI:33650
name: acyclic acetylene
def: "Acyclic (branched or unbranched) hydrocarbons having one or more carbon-carbon triple bonds." []
is_a: CHEBI:33644 ! acetylenes

[Term]
id: CHEBI:33653
name: aliphatic compound
def: "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33654
name: alicyclic compound
def: "An aliphatic compound having a carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system." []
is_a: CHEBI:33598 ! carbocyclic compound
is_a: CHEBI:33653 ! aliphatic compound

[Term]
id: CHEBI:33655
name: aromatic compound
def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekulé structure) is said to possess aromatic character." []
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33658
name: arene
def: "Any monocyclic or polycyclic aromatic hydrocarbon." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:33663 ! cyclic hydrocarbon

[Term]
id: CHEBI:33659
name: organic aromatic compound
is_a: CHEBI:33655 ! aromatic compound
is_a: CHEBI:33832 ! organic cyclic compound

[Term]
id: CHEBI:33661
name: monocyclic compound
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:33662
name: annulene
def: "A mancude monocyclic hydrocarbon without side chains of the general formula C<small><sub><em>n</em></sub></small>H<small><sub><em>n</em></sub></small> (<em>n</em> is an even number) or C<small><sub><em>n</em></sub></small>H<small><sub><em>n</em>+1</sub></small> (<em>n</em> is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [<em>n</em>]annulene, where <em>n</em> is the number of carbon atoms." []
is_a: CHEBI:33664 ! monocyclic hydrocarbon

[Term]
id: CHEBI:33663
name: cyclic hydrocarbon
is_a: CHEBI:24632 ! hydrocarbon
is_a: CHEBI:33598 ! carbocyclic compound

[Term]
id: CHEBI:33664
name: monocyclic hydrocarbon
is_a: CHEBI:33663 ! cyclic hydrocarbon

[Term]
id: CHEBI:33666
name: polycyclic hydrocarbon
is_a: CHEBI:33663 ! cyclic hydrocarbon
is_a: CHEBI:35294 ! carbopolycyclic compound

[Term]
id: CHEBI:33670
name: heteromonocyclic compound
is_a: CHEBI:33661 ! monocyclic compound
is_a: CHEBI:5686 ! heterocyclic compound

[Term]
id: CHEBI:33671
name: heteropolycyclic compound
def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." []
is_a: CHEBI:33635 ! polycyclic compound
is_a: CHEBI:5686 ! heterocyclic compound

[Term]
id: CHEBI:33672
name: heterobicyclic compound
def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." []
is_a: CHEBI:33636 ! bicyclic compound
is_a: CHEBI:5686 ! heterocyclic compound

[Term]
id: CHEBI:33673
name: zinc group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33340 ! has part zinc group element atom

[Term]
id: CHEBI:33674
name: s-block molecular entity
def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." []
is_a: CHEBI:33579 ! main group molecular entity
relationship: BFO:0000051 CHEBI:33559 ! has part s-block element atom

[Term]
id: CHEBI:33675
name: p-block molecular entity
def: "A main group molecular entity that contains one or more atoms of a p-block element." []
is_a: CHEBI:33579 ! main group molecular entity
relationship: BFO:0000051 CHEBI:33560 ! has part p-block element atom

[Term]
id: CHEBI:33676
name: d-block molecular entity
def: "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." []
is_a: CHEBI:33497 ! transition element molecular entity
relationship: BFO:0000051 CHEBI:33561 ! has part d-block element atom

[Term]
id: CHEBI:33677
name: f-block molecular entity
def: "A molecular entity containing one or more atoms of an f-block element." []
is_a: CHEBI:33497 ! transition element molecular entity
relationship: BFO:0000051 CHEBI:33562 ! has part f-block element atom

[Term]
id: CHEBI:33679
name: helium molecular entity
is_a: CHEBI:33583 ! noble gas molecular entity
is_a: CHEBI:33674 ! s-block molecular entity
relationship: BFO:0000051 CHEBI:30217 ! has part helium atom

[Term]
id: CHEBI:33692
name: hydrides
def: "Hydrides are chemical compounds of hydrogen with other chemical elements." []
is_a: CHEBI:33608 ! hydrogen molecular entity
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:33693
name: oxygen hydride
is_a: CHEBI:36902 ! chalcogen hydride

[Term]
id: CHEBI:33694
name: biomacromolecule
def: "A macromolecule formed by a living organism." []
is_a: CHEBI:33839 ! macromolecule
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33695
name: information biomacromolecule
is_a: CHEBI:33694 ! biomacromolecule

[Term]
id: CHEBI:33696
name: nucleic acid
def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), <small>D</small>-ribose or 2-deoxy-<small>D</small>-ribose and phosphoric acid." []
is_a: CHEBI:15986 ! polynucleotide
relationship: BFO:0000051 CHEBI:33791 ! has part canonical nucleoside residue
relationship: BFO:0000051 CHEBI:50297 ! has part canonical nucleotide residue

[Term]
id: CHEBI:33697
name: ribonucleic acid
def: "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." []
is_a: CHEBI:33696 ! nucleic acid
relationship: BFO:0000051 CHEBI:33792 ! has part canonical ribonucleoside residue
relationship: BFO:0000051 CHEBI:50299 ! has part canonical ribonucleotide residue

[Term]
id: CHEBI:33700
name: proteinogenic amino-acid residue
is_a: CHEBI:33710 ! alpha-amino-acid residue

[Term]
id: CHEBI:33702
name: polyatomic cation
def: "A cation consisting of more than one atom." []
is_a: CHEBI:36358 ! polyatomic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:33703
name: amino-acid cation
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:33702 ! polyatomic cation
relationship: RO:0018034 CHEBI:33709 ! is protonated form of amino acid

[Term]
id: CHEBI:33704
name: alpha-amino acid
def: "An amino acid in which the amino group is located on the carbon atom at the position α to the carboxy group." []
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018033 CHEBI:33719 ! is deprotonated form of alpha-amino-acid cation
relationship: RO:0018034 CHEBI:33558 ! is protonated form of alpha-amino-acid anion
relationship: RO:0018036 CHEBI:78608 ! is tautomer of alpha-amino-acid zwitterion

[Term]
id: CHEBI:33706
name: beta-amino acid
def: "A non-proteinogenic amino acid in which the amino group is located on the carbon atom at the position β to the carboxy group." []
is_a: CHEBI:83820 ! non-proteinogenic amino acid

[Term]
id: CHEBI:33707
name: gamma-amino acid
def: "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position γ to the carboxy group." []
is_a: CHEBI:83820 ! non-proteinogenic amino acid
relationship: RO:0018034 CHEBI:71666 ! is protonated form of gamma-amino acid anion

[Term]
id: CHEBI:33708
name: amino-acid residue
def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." []
is_a: CHEBI:33247 ! organic group
relationship: RO:0018033 CHEBI:58942 ! is deprotonated form of cationic amino-acid residue
relationship: RO:0018034 CHEBI:64898 ! is protonated form of anionic amino-acid residue
relationship: RO:0018037 CHEBI:33709 ! is substitutent group from amino acid

[Term]
id: CHEBI:33709
name: amino acid
def: "A carboxylic acid containing one or more amino groups." []
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:50047 ! organic amino compound
relationship: RO:0018033 CHEBI:33703 ! is deprotonated form of amino-acid cation
relationship: RO:0018034 CHEBI:37022 ! is protonated form of amino-acid anion

[Term]
id: CHEBI:33710
name: alpha-amino-acid residue
def: "An amino-acid residue derived from an α-amino acid." []
is_a: CHEBI:33708 ! amino-acid residue
relationship: RO:0018037 CHEBI:33704 ! is substitutent group from alpha-amino acid

[Term]
id: CHEBI:33719
name: alpha-amino-acid cation
is_a: CHEBI:33703 ! amino-acid cation
relationship: RO:0018034 CHEBI:33704 ! is protonated form of alpha-amino acid

[Term]
id: CHEBI:33720
name: carbohydrate acid
is_a: CHEBI:16646 ! carbohydrate
is_a: CHEBI:33575 ! carboxylic acid
relationship: RO:0018034 CHEBI:33721 ! is protonated form of carbohydrate acid anion

[Term]
id: CHEBI:33721
name: carbohydrate acid anion
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:33720 ! is deprotonated form of carbohydrate acid

[Term]
id: CHEBI:33731
name: cluster
def: "A cluster is a number of metal centres grouped close together which can have direct metal bonding interactions or interactions through a bridging ligand, but are not necessarily held together by these interactions." []
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:33732
name: homonuclear cluster
is_a: CHEBI:33731 ! cluster

[Term]
id: CHEBI:33734
name: polyboron hydride
is_a: CHEBI:33588 ! boron hydride
is_a: CHEBI:33735 ! polyboron cluster

[Term]
id: CHEBI:33735
name: polyboron cluster
is_a: CHEBI:33732 ! homonuclear cluster

[Term]
id: CHEBI:3374
name: capsaicin
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:46931 ! capsaicinoid
is_a: CHEBI:51683 ! methoxybenzenes
relationship: RO:0000087 CHEBI:140535 ! has role TRPV1 agonist
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38634 ! has role voltage-gated sodium channel blocker
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:33741
name: chromium group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33350 ! has part chromium group element atom

[Term]
id: CHEBI:33743
name: manganese group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33352 ! has part manganese group element atom

[Term]
id: CHEBI:33744
name: iron group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33356 ! has part iron group element atom

[Term]
id: CHEBI:33745
name: copper group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33366 ! has part copper group element atom

[Term]
id: CHEBI:33746
name: vanadium group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33347 ! has part vanadium group element atom

[Term]
id: CHEBI:33747
name: nickel group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33362 ! has part nickel group element atom

[Term]
id: CHEBI:33748
name: nickel molecular entity
is_a: CHEBI:33747 ! nickel group molecular entity
relationship: BFO:0000051 CHEBI:28112 ! has part nickel atom

[Term]
id: CHEBI:33749
name: platinum molecular entity
is_a: CHEBI:33747 ! nickel group molecular entity
relationship: BFO:0000051 CHEBI:33364 ! has part platinum

[Term]
id: CHEBI:33767
name: cobalt group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33358 ! has part cobalt group element atom

[Term]
id: CHEBI:33768
name: titanium group molecular entity
is_a: CHEBI:33676 ! d-block molecular entity
relationship: BFO:0000051 CHEBI:33345 ! has part titanium group element atom

[Term]
id: CHEBI:33780
name: beryllium molecular entity
is_a: CHEBI:33299 ! alkaline earth molecular entity
relationship: BFO:0000051 CHEBI:30501 ! has part beryllium atom

[Term]
id: CHEBI:33791
name: canonical nucleoside residue
is_a: CHEBI:50320 ! nucleoside residue

[Term]
id: CHEBI:33792
name: canonical ribonucleoside residue
is_a: CHEBI:33791 ! canonical nucleoside residue

[Term]
id: CHEBI:33793
name: canonical deoxyribonucleoside residue
is_a: CHEBI:33791 ! canonical nucleoside residue

[Term]
id: CHEBI:33798
name: tetraric acid anion
is_a: CHEBI:22289 ! aldaric acid anion
relationship: RO:0018033 CHEBI:26933 ! is deprotonated form of tetraric acid

[Term]
id: CHEBI:3380
name: captopril
def: "A <small>L</small>-proline derivative in which <small>L</small>-proline is substituted on nitrogen with a (2<i>S</i>)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug." []
is_a: CHEBI:46701 ! pyrrolidinemonocarboxylic acid
is_a: CHEBI:46766 ! N-acylpyrrolidine
is_a: CHEBI:47908 ! alkanethiol
is_a: CHEBI:51569 ! N-acyl-amino acid
is_a: CHEBI:84186 ! L-proline derivative
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35457 ! has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:33815
name: oxygen-18 atom
def: "The stable isotope of oxygen with relative atomic mass 17.999160 and 0.205 atom percent natural abundance." []
is_a: CHEBI:25805 ! oxygen atom

[Term]
id: CHEBI:33822
name: organic hydroxy compound
def: "An organic compound having at least one hydroxy group attached to a carbon atom." []
is_a: CHEBI:24651 ! hydroxides
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33823
name: enol
def: "Alkenols; the term refers specifically to vinylic alcohols, which have the structure HOCR'=CR<small><sub>2</sub></small>. Enols are tautomeric with aldehydes (R' = H) or ketones (R' ≠ H)." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0018034 CHEBI:142839 ! is protonated form of enolate

[Term]
id: CHEBI:33832
name: organic cyclic compound
def: "Any organic molecule that consists of atoms connected in the form of a ring." []
is_a: CHEBI:33595 ! cyclic compound
is_a: CHEBI:72695 ! organic molecule

[Term]
id: CHEBI:33833
name: heteroarene
def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (‒C=) and/or vinylene (‒CH=CH‒) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous π-electron system characteristic of aromatic systems and a number of out-of-plane π-electrons corresponding to the Hückel rule (4<em>n</em>+2)." []
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:33836
name: benzenoid aromatic compound
is_a: CHEBI:33598 ! carbocyclic compound
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:33837
name: conjugated protein
def: "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." []
is_a: CHEBI:36080 ! protein

[Term]
id: CHEBI:33838
name: nucleoside
def: "An <em>N</em>-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents." []
is_a: CHEBI:21731 ! N-glycosyl compound
is_a: CHEBI:26912 ! oxolanes
is_a: CHEBI:61120 ! nucleobase-containing molecular entity

[Term]
id: CHEBI:33839
name: macromolecule
def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." []
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:33842
name: aromatic annulene
is_a: CHEBI:33662 ! annulene
is_a: CHEBI:33847 ! monocyclic arene

[Term]
id: CHEBI:33847
name: monocyclic arene
def: "A monocyclic aromatic hydrocarbon." []
is_a: CHEBI:33658 ! arene

[Term]
id: CHEBI:33848
name: polycyclic arene
def: "A polycyclic aromatic hydrocarbon." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33658 ! arene
is_a: CHEBI:33666 ! polycyclic hydrocarbon
relationship: RO:0000087 CHEBI:138015 ! has role endocrine disruptor
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:33853
name: phenols
def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:33854
name: aromatic alcohol
def: "Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring." []
is_a: CHEBI:30879 ! alcohol
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:33855
name: arenecarbaldehyde
def: "Any aldehyde in which the carbonyl group is attached to an aromatic moiety." []
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:33856
name: aromatic amino acid
def: "An amino acid whose structure includes an aromatic ring." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018034 CHEBI:63473 ! is protonated form of aromatic amino-acid anion
relationship: RO:0018036 CHEBI:76042 ! is tautomer of aromatic amino-acid zwitterion

[Term]
id: CHEBI:33857
name: aromatic primary alcohol
def: "Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:33854 ! aromatic alcohol

[Term]
id: CHEBI:33859
name: aromatic carboxylic acid
def: "Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring." []
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:33659 ! organic aromatic compound
relationship: RO:0018034 CHEBI:91007 ! is protonated form of aromatic carboxylate

[Term]
id: CHEBI:33860
name: aromatic amine
def: "An amino compound in which the amino group is linked directly to an aromatic system." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:33861
name: transition element coordination entity
is_a: CHEBI:33240 ! coordination entity
is_a: CHEBI:33497 ! transition element molecular entity

[Term]
id: CHEBI:33862
name: platinum coordination entity
is_a: CHEBI:33749 ! platinum molecular entity
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:3387
name: carbamazepine
def: "A dibenzoazepine that is 5<em>H</em>-dibenzo[<em>b</em>,<em>f</em>]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47804 ! dibenzoazepine
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:53802 ! dibenzooxazepine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35477 ! has role antimanic drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38633 ! has role sodium channel blocker
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:52290 ! has role mitogen
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:64370 ! has role glutamate transporter activator
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:33888
name: cobalt molecular entity
is_a: CHEBI:33767 ! cobalt group molecular entity
relationship: BFO:0000051 CHEBI:27638 ! has part cobalt atom

[Term]
id: CHEBI:33890
name: cobalt coordination entity
is_a: CHEBI:33861 ! transition element coordination entity
is_a: CHEBI:33888 ! cobalt molecular entity

[Term]
id: CHEBI:33892
name: iron coordination entity
is_a: CHEBI:24873 ! iron molecular entity
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:33893
name: reagent
def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:3390
name: carbaryl
def: "A carbamate ester obtained by the formal condensation of  1-naphthol with methylcarbamic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:25477 ! naphthalenes
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35219 ! has role plant growth retardant
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38461 ! has role carbamate insecticide
relationship: RO:0018038 CHEBI:10319 ! has functional parent 1-naphthol
relationship: RO:0018038 CHEBI:45379 ! has functional parent methylcarbamic acid

[Term]
id: CHEBI:33904
name: molluscicide
def: "A substance used to destroy pests of the phylum <em>Mollusca</em>." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:33906
name: cobalt corrinoid
is_a: CHEBI:33890 ! cobalt coordination entity
is_a: CHEBI:33909 ! metallotetrapyrrole
is_a: CHEBI:33913 ! corrinoid

[Term]
id: CHEBI:33909
name: metallotetrapyrrole
is_a: CHEBI:36309 ! cyclic tetrapyrrole

[Term]
id: CHEBI:33910
name: chlorins
def: "Dihydroporphyrin compounds where saturated carbon atoms are located at the nonfused carbon atoms of one of the pyrrole rings." []
is_a: CHEBI:52535 ! dihydroporphyrin

[Term]
id: CHEBI:33913
name: corrinoid
def: "A derivative of the corrin nucleus, which contains four reduced or partly reduced pyrrole rings joined in a macrocycle by three =C‒ groups and one direct carbon-carbon bond linking α positions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36309 ! cyclic tetrapyrrole
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:33914
name: aldotriose
is_a: CHEBI:15693 ! aldose
is_a: CHEBI:27137 ! triose

[Term]
id: CHEBI:33916
name: aldopentose
def: "A pentose with a (potential) aldehyde group at one end." []
is_a: CHEBI:15693 ! aldose
is_a: CHEBI:25901 ! pentose

[Term]
id: CHEBI:33917
name: aldohexose
def: "A hexose with a (potential) aldehyde group at one end." []
is_a: CHEBI:15693 ! aldose
is_a: CHEBI:18133 ! hexose

[Term]
id: CHEBI:3392
name: carbendazim
def: "A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls  <em>Ascomycetes</em>, <em>Fungi Imperfecti</em>, and <em>Basidiomycetes</em> on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables." []
is_a: CHEBI:87036 ! benzimidazole fungicide
is_a: CHEBI:87064 ! benzimidazolylcarbamate fungicide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:61951 ! has role microtubule-destabilising agent
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:27822 ! has functional parent 2-aminobenzimidazole

[Term]
id: CHEBI:33937
name: macronutrient
def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." []
is_a: CHEBI:33284 ! nutrient

[Term]
id: CHEBI:3394
name: carbetamide
def: "A carbamate ester obtained by the formal condensation of  phenylcarbamic acid with the hydroxy group of <em>N</em>-ethyl-2-hydroxypropanamide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:29347 ! monocarboxylic acid amide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:52496 ! has functional parent phenylcarbamic acid

[Term]
id: CHEBI:33942
name: ribose
def: "Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, <small>D</small>- and <small>L</small>-ribose, of which only the former is found in nature." []
is_a: CHEBI:33916 ! aldopentose

[Term]
id: CHEBI:33958
name: halide salt
is_a: CHEBI:24866 ! salt
is_a: CHEBI:37578 ! halide
relationship: BFO:0000051 CHEBI:16042 ! has part halide anion

[Term]
id: CHEBI:33963
name: metallocene
def: "Organometallic coordination compounds in which one atom of a transition metal such as iron, ruthenium or osmium is bonded to and only to the face of two cyclopentadienyl [η<small><sup>5</small></sup>-(C<small><sub>5</sub></small>H<small><sub>5</sub></small>)] ligands which lie in parallel planes. The term should not be used for analogues having rings other than cyclopentadienyl as ligands." []
is_a: CHEBI:33861 ! transition element coordination entity
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:33964
name: silver molecular entity
is_a: CHEBI:33745 ! copper group molecular entity
relationship: BFO:0000051 CHEBI:30512 ! has part silver atom

[Term]
id: CHEBI:33966
name: elemental silver
is_a: CHEBI:33964 ! silver molecular entity

[Term]
id: CHEBI:33968
name: silver salt
is_a: CHEBI:33964 ! silver molecular entity

[Term]
id: CHEBI:33969
name: gold molecular entity
is_a: CHEBI:33745 ! copper group molecular entity
relationship: BFO:0000051 CHEBI:29287 ! has part gold atom

[Term]
id: CHEBI:33970
name: elemental gold
is_a: CHEBI:33969 ! gold molecular entity

[Term]
id: CHEBI:33971
name: gold coordination entity
is_a: CHEBI:33861 ! transition element coordination entity
is_a: CHEBI:33969 ! gold molecular entity

[Term]
id: CHEBI:33973
name: elemental magnesium
is_a: CHEBI:25108 ! magnesium molecular entity

[Term]
id: CHEBI:33977
name: metallic base
is_a: CHEBI:52625 ! inorganic hydroxy compound

[Term]
id: CHEBI:33978
name: alkali metal hydroxide
is_a: CHEBI:33296 ! alkali metal molecular entity
is_a: CHEBI:33977 ! metallic base

[Term]
id: CHEBI:33983
name: deoxymannose
is_a: CHEBI:23628 ! deoxyhexose

[Term]
id: CHEBI:33984
name: fucose
def: "Any deoxygalactose that is deoxygenated at the 6-position." []
synonym: "6-Deoxygalactose" EXACT [KEGG_COMPOUND]
synonym: "Fucose" EXACT [KEGG_COMPOUND]
is_a: CHEBI:23622 ! deoxygalactose

[Term]
id: CHEBI:33988
name: caesium hydroxide
is_a: CHEBI:33978 ! alkali metal hydroxide
is_a: CHEBI:37128 ! caesium molecular entity

[Term]
id: CHEBI:33989
name: alkaline earth hydroxide
is_a: CHEBI:33299 ! alkaline earth molecular entity
is_a: CHEBI:33977 ! metallic base

[Term]
id: CHEBI:34024
name: 1,1,1,2-tetrachloroethane
is_a: CHEBI:36016 ! chloroethanes

[Term]
id: CHEBI:34031
name: 1,1-dichloroethene
def: "A member of the class of chloroethenes that is ethene in which both of the hydrogens attached to one of the carbons are replaced by chlorines." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23142 ! chloroethenes
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:34036
name: 1,2,3-Trichloropropane
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:34037
name: 1,2,3-trimethylbenzene
def: "A trimethylbenzene carrying methyl groups at positions 1, 2 and 3. It has been found in  <em>Centaurium erythraea</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38641 ! trimethylbenzene
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:34039
name: 1,2,4-trimethylbenzene
def: "A trimethylbenzene carrying methyl groups at positions 1, 2 and 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38641 ! trimethylbenzene
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:34043
name: 1,2-phenylenediamine
def: "A phenylenediamine in which the two amino groups are <em>ortho</em> to each other." []
is_a: CHEBI:17499 ! hydrogen donor
is_a: CHEBI:51402 ! phenylenediamine
relationship: RO:0018040 CHEBI:16716 ! has parent hydride benzene

[Term]
id: CHEBI:34044
name: 1,2-Dibromo-3-chloropropane
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:3405
name: carboxin
def: "An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment." []
is_a: CHEBI:13248 ! anilide
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:38106 ! organosulfur heterocyclic compound
is_a: CHEBI:51751 ! enamide
is_a: CHEBI:87015 ! anilide fungicide
relationship: RO:0000087 CHEBI:83072 ! has role EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:34053
name: 1,2-dinitrobenzene
is_a: CHEBI:51396 ! dinitrobenzene

[Term]
id: CHEBI:34066
name: 1,6-Dinitropyrene
is_a: CHEBI:59659 ! pyrenes

[Term]
id: CHEBI:34069
name: 1,8-Dinitropyrene
is_a: CHEBI:59659 ! pyrenes

[Term]
id: CHEBI:34073
name: Delta(1)-progesterone
def: "A 3-oxo Δ<small><sup>4</small></sup>-steroid that is progesterone which has been oxidised to introduce a double bond between positions 1 and 2." []
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0018038 CHEBI:17026 ! has functional parent progesterone
relationship: RO:0018040 CHEBI:35508 ! has parent hydride steroid fundamental parent

[Term]
id: CHEBI:34104
name: 1-nitronaphthalene
def: "A mononitronaphthalene substituted by a nitro group at position 1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50632 ! mononitronaphthalene
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34107
name: 1-nitropyrene
def: "A nitroarene that is pyrene substituted at the 1-position by a nitro group. A by-product of combustion,  it is the predominant nitrated polycyclic aromatic hydrocarbon emitted in a diesel engine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51132 ! nitroarene
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018040 CHEBI:39106 ! has parent hydride pyrene

[Term]
id: CHEBI:34197
name: 2,2',3,3',5,5'-hexachlorobiphenyl
def: "A hexachlorobiphenyl that is biphenyl in which the hydrogens at the 2, 3, and 5 positions of each of the benzene rings are replaced by chlorines." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:34199
name: 2,2',3,3',6,6'-hexachlorobiphenyl
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:34202
name: 2,2',4,4',5,5'-hexachlorobiphenyl
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:34203
name: 2,2',4,4',6,6'-hexachlorobiphenyl
def: "A hexachlorobiphenyl that is biphenyl in which both of the phenyl rings are substituted at positons 2, 4, and 6 by chlorines." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:34204
name: 2,2',4,4'-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl that is biphenyl in which each of the phenyl groups is substituted at positions 2 and 4 by chlorines." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl

[Term]
id: CHEBI:34205
name: 2,2',4,5-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl that is biphenyl in which the hydrogens at positions 2, 4, 5, and 2' are replaced by chlorines." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:34206
name: 2,2',5,5'-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl that is biphenyl in which the hydrogens at the 2 and 5 position of each benzene ring are replaced by chlorines." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl

[Term]
id: CHEBI:34215
name: 2,3',5-trichlorobiphenyl
def: "A trichlorobiphenyl that is 1,4-dichlorobenzene in which one of the hydrogens has been replaced by a 3-chlorophenyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36719 ! trichlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:34216
name: 2,3,3',4,5-pentachlorobiphenyl
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:36721 ! pentachlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:34218
name: 2,3,4,4'-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl in which the chlorines are positions at positions 2, 3, 4, and 4'." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:34219
name: 2,3,4,5,6-pentachlorobiphenyl
is_a: CHEBI:36721 ! pentachlorobiphenyl
is_a: CHEBI:83390 ! pentachlorobenzenes

[Term]
id: CHEBI:34221
name: 2,3,4,5-tetrachlorobiphenyl
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl

[Term]
id: CHEBI:34222
name: 2,3,4-trichlorobiphenyl
def: "A trichlorobiphenyl that is biphenyl in which the hydrogens at positions 2, 3, and 4 on one of the benzene rings are replaced by chlorines." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36719 ! trichlorobiphenyl

[Term]
id: CHEBI:34224
name: 2,3,5,6-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl that is biphenyl in which one of the phenyl groups is substituted by chlorines at positions 2, 3, 5, and 6." []
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl

[Term]
id: CHEBI:34225
name: 2,3,6-trichlorobiphenyl
def: "A trichlorobiphenyl that is 1,2,4-trichlorobenzene in which the hydrogen at position 3 has been replaced by a phenyl group." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36719 ! trichlorobiphenyl

[Term]
id: CHEBI:34232
name: 2,4'-dichlorobiphenyl
def: "A dichlorobiphenyl that is chlorobenzene in which the hydrogen at position 2 has been replaced by a 4-chlorophenyl group." []
is_a: CHEBI:36718 ! dichlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:34233
name: 2,4,4',6-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl that is 1,3,5-trichlorobenzene in which one of the hydrogens is replaced by a <em>p</em>-chlorophenyl group." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:34237
name: 2,4-diaminotoluene
def: "An aminotoluene that is <em>para</em>-toluidine with an additional amino group at position 2." []
is_a: CHEBI:22531 ! aminotoluene
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018038 CHEBI:37825 ! has functional parent p-toluidine

[Term]
id: CHEBI:3424
name: carnitinium
def: "A quaternary ammonium ion that is the the conjugate acid of carnitine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35267 ! quaternary ammonium ion
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17126 ! is protonated form of carnitine
relationship: RO:0018038 CHEBI:16080 ! has functional parent gamma-amino-beta-hydroxybutyric acid

[Term]
id: CHEBI:34241
name: 2,4-xylenol
def: "A member of the class of phenols that phenol substituted by methyl groups at positions 2 and 4." []
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:87034 ! aromatic fungicide
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0018040 CHEBI:28488 ! has parent hydride m-xylene

[Term]
id: CHEBI:34246
name: 2,5-dichlorobiphenyl
def: "A dichlorobiphenyl that is <em>p</em>-dichlorobenzene in which one of the hydrogens has been replaced by a phenyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36718 ! dichlorobiphenyl

[Term]
id: CHEBI:34247
name: 2,6-di-tert-butyl-4-methylphenol
def: "A member of the class of  phenols that is 4-methylphenol substituted by <em>tert</em>-butyl groups at positions 2 and 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:38976 ! alkylbenzene
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:64047 ! has role food additive
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0018038 CHEBI:15882 ! has functional parent phenol

[Term]
id: CHEBI:34249
name: 2,6-dichlorobiphenyl
def: "A dichlorobiphenyl that is 1,3-dichlorobenzene in which the hydrogen at position 2 is replaced by a phenyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36718 ! dichlorobiphenyl

[Term]
id: CHEBI:34251
name: 2,6-dimethylnaphthalene
def: "A dimethylnaphthalene carrying methyl groups at positions 2 and 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48853 ! dimethylnaphthalene
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34258
name: 2-Aminoanthraquinone
is_a: CHEBI:22580 ! anthraquinone

[Term]
id: CHEBI:34283
name: oxybenzone
def: "A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24677 ! hydroxybenzophenone
is_a: CHEBI:25235 ! monomethoxybenzene
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50267 ! has role protective agent
relationship: RO:0000087 CHEBI:73335 ! has role ultraviolet filter
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34292
name: 1,3-benzothiazole-2-thiol
def: "1,3-Benzothiazole substituted at the 2-position with a sulfanyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37947 ! benzothiazoles
is_a: CHEBI:82711 ! aryl thiol
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:34303
name: 2-sec-butylphenol
def: "A member of the class of phenols that is phenol carrying a butan-2-yl group at position 2." []
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:34304
name: fenobucarb
def: "A carbamate ester obtained by the formal condensation of 2-<em>sec</em>-butylphenol with methylcarbamic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:34303 ! has functional parent 2-sec-butylphenol
relationship: RO:0018038 CHEBI:45379 ! has functional parent methylcarbamic acid

[Term]
id: CHEBI:34317
name: 3,3',4,4',5-pentachlorobiphenyl
def: "A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36721 ! pentachlorobiphenyl

[Term]
id: CHEBI:34320
name: 3,3'-Dimethylbenzidine
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:27024 ! toluenes

[Term]
id: CHEBI:34326
name: 3,5-dichlorobiphenyl
def: "A dichlorobiphenyl that is 1,3-dichlorobenzene in which the hydrogen at position 5 has been replaced by a phenyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36718 ! dichlorobiphenyl

[Term]
id: CHEBI:34342
name: 3-methylcholanthrene
def: "A pentacyclic <em>ortho</em>- and <em>peri</em>-fused polycyclic arene consisting of a dihydrocyclopenta[<em>ij</em>]tetraphene ring system with a methyl substituent at the 3-position." []
is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene
relationship: RO:0000087 CHEBI:72768 ! has role aryl hydrocarbon receptor agonist

[Term]
id: CHEBI:3435
name: carrageenan
def: "A family of sulfated polysaccharides extracted from red seaweeds. The name is derived from a common name of red algae <em>Chondrus crispus</em>, \"carrageen moss\" (Irish moss)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37944 ! polysaccharide sulfate
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018038 CHEBI:37165 ! has functional parent galactan

[Term]
id: CHEBI:34364
name: 4,4'-dichlorobiphenyl
def: "A dichlorobiphenyl carrying chloro groups at positions 4 and 4' respectively." []
is_a: CHEBI:36718 ! dichlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:34399
name: 4-Chloronitrobenzene
is_a: CHEBI:35716 ! C-nitro compound

[Term]
id: CHEBI:34432
name: 4-octylphenol
def: "A member of the class of phenols that is phenol which is substituted at the <em>para</em>- position by an octyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35195 ! has role surfactant
relationship: RO:0000087 CHEBI:76988 ! has role xenoestrogen

[Term]
id: CHEBI:34440
name: 4-nonylphenol
def: "A member of the class of phenols that is phenol which is <em>para</em>-substituted with a nonyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34520
name: acephate
def: "A  phosphoramide that is  methamidophos in which one of the hydrogens is replaced by an acetyl group." []
is_a: CHEBI:17102 ! phosphoramide
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:37716 ! mixed diacylamine
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38721 ! has functional parent methamidophos

[Term]
id: CHEBI:34556
name: bendiocarb
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:38298 ! benzodioxoles
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38461 ! has role carbamate insecticide
relationship: RO:0018038 CHEBI:45379 ! has functional parent methylcarbamic acid

[Term]
id: CHEBI:34572
name: allethrin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0018038 CHEBI:3680 ! has functional parent chrysanthemic acid

[Term]
id: CHEBI:34573
name: Bis(2-chloroethyl)ether
is_a: CHEBI:25698 ! ether

[Term]
id: CHEBI:34575
name: bisphenol F
def: "A bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22901 ! bisphenol
is_a: CHEBI:51614 ! diarylmethane
relationship: RO:0000087 CHEBI:76988 ! has role xenoestrogen
relationship: RO:0000087 CHEBI:78299 ! has role environmental food contaminant

[Term]
id: CHEBI:34591
name: bromodichloromethane
def: "A halomethane that is dichloromethane in which oneof the hydrogens has been replaced by a bromine atom. It occurs as a contaminant in drinking water." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39279 ! halomethane
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34595
name: Butylbenzyl phthalate
is_a: CHEBI:90628 ! benzyl ester

[Term]
id: CHEBI:34608
name: captan
def: "A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops." []
is_a: CHEBI:24897 ! isoindoles
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:87198 ! phthalimide fungicide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:34611
name: carbofuran
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:38830 ! 1-benzofurans
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38461 ! has role carbamate insecticide

[Term]
id: CHEBI:34620
name: quinomethionate
def: "A dithioloquinoxaline that results from the formal condensation of 6-methylquinoxaline-2,3-dithiol with phosgene. It has been used as a fungicide and acaricide for the control of mites and powdery mildew on citrus, vegetables, and walnuts, but is not approved for use in the EU." []
is_a: CHEBI:38819 ! quinoxaline antifungal agent
is_a: CHEBI:38820 ! quinoxaline acaricide
is_a: CHEBI:38919 ! dithioloquinoxaline
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:34623
name: chlordane
is_a: CHEBI:23457 ! cyclodiene organochlorine insecticide
relationship: RO:0000087 CHEBI:38999 ! has role GABA-gated chloride channel antagonist
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0018040 CHEBI:37910 ! has parent hydride indene

[Term]
id: CHEBI:34624
name: Chloroacetyl chloride
is_a: CHEBI:37579 ! acyl halide

[Term]
id: CHEBI:34626
name: Chlorobenzilate
is_a: CHEBI:51614 ! diarylmethane

[Term]
id: CHEBI:34631
name: chlorpyrifos
def: "An  organic thiophosphate that is <em>O</em>,<em>O</em>-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34632
name: chlorpyrifos-methyl
def: "An organic thiophosphate that is <em>O</em>,<em>O</em>-dimethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34656
name: cumene
def: "An alkylbenzene that is benzene carrying an isopropyl group." []
is_a: CHEBI:38976 ! alkylbenzene

[Term]
id: CHEBI:34666
name: decachlorobiphenyl
def: "A polychlorobiphenyl that is biphenyl in which all of the hydrogens are replaced by chlorines." []
is_a: CHEBI:53156 ! polychlorobiphenyl
is_a: CHEBI:83390 ! pentachlorobenzenes

[Term]
id: CHEBI:34674
name: dextran sulfate
def: "A polymer composed of repeating (1→6)-α-linked anhydroglucose sulfate units." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37944 ! polysaccharide sulfate
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0018034 CHEBI:191931 ! is protonated form of dextran sulfate anion
relationship: RO:0018038 CHEBI:18269 ! has functional parent (1->6)-alpha-D-glucan

[Term]
id: CHEBI:34682
name: diazinon
def: "A member of the class of  pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:39447 ! pyrimidines
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38629 ! has functional parent 2-isopropyl-6-methylpyrimidin-4-ol

[Term]
id: CHEBI:34687
name: dibutyl phthalate
def: "A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of  butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans." []
is_a: CHEBI:35484 ! phthalate ester
is_a: CHEBI:36054 ! benzoate ester
is_a: CHEBI:51307 ! diester
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:67239 ! has role EC 3.2.1.20 (alpha-glucosidase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:79056 ! has role plasticiser
relationship: RO:0018038 CHEBI:28885 ! has functional parent butan-1-ol

[Term]
id: CHEBI:34690
name: dichlorvos
def: "An alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate." []
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:37494 ! alkenyl phosphate
is_a: CHEBI:38657 ! organochlorine acaricide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35443 ! has role anthelminthic drug
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:34692
name: dicofol
def: "A tertiary alcohol that is DDT in which the benzylic hydrogen has been replaced by a hydroxy group." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:38657 ! organochlorine acaricide
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0018038 CHEBI:16130 ! has functional parent DDT

[Term]
id: CHEBI:34695
name: Dicyclopentadiene
is_a: CHEBI:33642 ! cyclic olefin

[Term]
id: CHEBI:34696
name: dieldrin
def: "An organochlorine compound resulting from the epoxidation of the double bond of aldrin. It is the active metabolite of the proinsecticde aldrin." []
is_a: CHEBI:25705 ! organochlorine insecticide
is_a: CHEBI:32955 ! epoxide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018038 CHEBI:2564 ! has functional parent aldrin

[Term]
id: CHEBI:34698
name: diethyl phthalate
def: "The diethyl ester of benzene-1,2-dicarboxylic acid." []
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:35484 ! phthalate ester
is_a: CHEBI:36054 ! benzoate ester
is_a: CHEBI:51307 ! diester
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:79056 ! has role plasticiser

[Term]
id: CHEBI:34699
name: diethyl sulfate
def: "The diethyl ester of sulfuric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29281 ! alkyl sulfate
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:34703
name: diflubenzuron
def: "A benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group." []
is_a: CHEBI:38494 ! benzoylurea insecticide
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:67105 ! has role insect sterilant
relationship: RO:0018038 CHEBI:38584 ! has functional parent 1,3-difluorobenzene

[Term]
id: CHEBI:34714
name: dimethoate
def: "A monocarboxylic acid amide that is <em>N</em>-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38731 ! has functional parent N-methyl-2-sulfanylacetamide

[Term]
id: CHEBI:34719
name: dinoseb
def: "A  racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-dinoseb." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83633 ! has part (R)-dinoseb
relationship: BFO:0000051 CHEBI:83636 ! has part (S)-dinoseb
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34727
name: domoic acid
def: "An <small>L</small>-proline derivative that is <small>L</small>-proline substituted by a carboxymethyl group at position 3 and a 6-carboxyhepta-2,4-dien-2-yl group at position 4. It is produced by the diatomic algal <em>Pseudo-nitzschia</em>. It is an analogue of kainic acid and a neurotoxin which causes amnesic shellfish poisoning (ASP)." []
is_a: CHEBI:27093 ! tricarboxylic acid
is_a: CHEBI:46767 ! pyrrolidinecarboxylic acid
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
is_a: CHEBI:84186 ! L-proline derivative
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:51372 ! has role neuromuscular agent
relationship: RO:0000087 CHEBI:59174 ! has role hapten
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:167470 ! is protonated form of domoate(2-)

[Term]
id: CHEBI:34733
name: EPN
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37592 ! organic phosphonate
is_a: CHEBI:37735 ! phosphonic ester
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:347401
name: pentolinium ion
def: "A dication whose structure comprises a pentane backbone linking two 1-methylpyrrolidinium groups; a nicotinic antagonist used as a ganglionic blocking agent in hypertension." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:46775 ! N-alkylpyrrolidine
relationship: BFO:0000051 CHEBI:52145 ! has part pyrrolidinium ion

[Term]
id: CHEBI:34741
name: equol
is_a: CHEBI:76250 ! hydroxyisoflavans

[Term]
id: CHEBI:34750
name: Ethylenethiourea
is_a: CHEBI:38261 ! imidazolidines

[Term]
id: CHEBI:34760
name: fensulfothion
is_a: CHEBI:22063 ! sulfoxide
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38688 ! has functional parent 4-(methylsulfinyl)phenol

[Term]
id: CHEBI:34761
name: fenthion
def: "An organic thiophosphate that is <em>O</em>,<em>O</em>-dimethyl hydrogen phosphorothioate in which the hydrogen atom of the hydroxy group is replaced by a 3-methyl-4-(methylsulfanyl)phenyl group. It exhibits  acaricidal and insecticidal activities." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38681 ! has functional parent 4-(methylsulfanyl)-m-cresol

[Term]
id: CHEBI:34768
name: furfural
def: "An aldehyde that is furan with the hydrogen at position 2 substituted by a formyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:24129 ! furans
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:77523 ! has role Maillard reaction product
relationship: RO:0018038 CHEBI:35559 ! has functional parent furan

[Term]
id: CHEBI:34779
name: glyoxal
def: "The dialdehyde that is the smallest possible and which consists of ethane having oxo groups on both carbons." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38124 ! dialdehyde
relationship: RO:0000087 CHEBI:25944 ! has role pesticide
relationship: RO:0000087 CHEBI:26155 ! has role plant growth regulator
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:34785
name: heptachlor
def: "A cyclodiene organochlorine insecticide that is 3a,4,7,7a-tetrahydro-1<em>H</em>-4,7-methanoindene substituted by chlorine atoms at positions 1, 4, 5, 6, 7, 8 and 8. Formerly used to kill termites, ants and other insects in agricultural and domestic situations." []
is_a: CHEBI:23457 ! cyclodiene organochlorine insecticide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38999 ! has role GABA-gated chloride channel antagonist
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0018040 CHEBI:41921 ! has parent hydride 1H-indene

[Term]
id: CHEBI:34786
name: Heptachlor epoxide
is_a: CHEBI:46942 ! oxanes

[Term]
id: CHEBI:3479
name: cefadroxil
def: "A cephalosporin bearing methyl and  (2<i>R</i>)-2-amino-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton." []
is_a: CHEBI:23066 ! cephalosporin
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0018034 CHEBI:53669 ! is protonated form of cefadroxil(1-)

[Term]
id: CHEBI:34800
name: isophorone
def: "A cyclic ketone, the structure of which is that of cyclohex-2-en-1-one substituted by methyl groups at positions 3, 5 and 5." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:51689 ! enone
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:34833
name: 1,3,5-trimethylbenzene
def: "A trimethylbenzene carrying methyl substituents at positions 1, 3 and 5." []
is_a: CHEBI:38641 ! trimethylbenzene

[Term]
id: CHEBI:34840
name: methyl methacrylate
def: "An enoate ester having methacrylic acid as the carboxylic acid component and methanol as the alcohol component." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:51702 ! enoate ester
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:74236 ! has role polymerisation monomer
relationship: RO:0018038 CHEBI:25219 ! has functional parent methacrylic acid

[Term]
id: CHEBI:34846
name: metribuzin
def: "A member of the class of  1,2,4-triazines that is 1,2,4-triazin-5(4<em>H</em>)-one substituted by an amino group at position 4, <em>tert</em>-butyl group at position 6 and a methylsulfanyl group at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:39410 ! 1,2,4-triazines
is_a: CHEBI:3992 ! cyclic ketone
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:34848
name: mevastatin
def: "A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from <em>Penicillium citrinum</em> and from <em>Penicillium brevicompactum</em>, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals." []
is_a: CHEBI:142348 ! hexahydronaphthalenes
is_a: CHEBI:26188 ! polyketide
is_a: CHEBI:75885 ! 2-pyranones
is_a: CHEBI:87632 ! statin (naturally occurring)
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:76964 ! has role Penicillium metabolite
relationship: RO:0000087 CHEBI:77255 ! has role EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor

[Term]
id: CHEBI:34852
name: mirex
is_a: CHEBI:25705 ! organochlorine insecticide
is_a: CHEBI:39226 ! chlorocarbon
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:348530
name: thiouracil
def: "A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48546 ! pyrimidinethione
is_a: CHEBI:67142 ! nucleobase analogue
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:50671 ! has role antithyroid drug
relationship: RO:0018038 CHEBI:17568 ! has functional parent uracil

[Term]
id: CHEBI:34856
name: morpholine
def: "An organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family." []
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:38785 ! morpholines
relationship: RO:0018033 CHEBI:167868 ! is deprotonated form of morpholinium

[Term]
id: CHEBI:34873
name: N-nitrosodiethylamine
def: "A nitrosamine that is <em>N</em>-ethylethanamine substituted by a nitroso group at the <em>N</em>-atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35803 ! nitrosamine
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent

[Term]
id: CHEBI:34875
name: N-Nitrosodiphenylamine
is_a: CHEBI:25996 ! phenylhydrazines

[Term]
id: CHEBI:34877
name: N-Phenyl-2-naphthylamine
is_a: CHEBI:25477 ! naphthalenes

[Term]
id: CHEBI:34892
name: nocodazole
def: "A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:26961 ! thiophenes
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:61951 ! has role microtubule-destabilising agent

[Term]
id: CHEBI:34905
name: paraquat
def: "An organic cation that consists of 4,4'-bipyridine bearing two <em>N</em>-methyl substituents loctated at the 1- and 1'-positions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25697 ! organic cation
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0018040 CHEBI:30985 ! has parent hydride 4,4'-bipyridine

[Term]
id: CHEBI:34908
name: pentachloronitrobenzene
def: "A <em>C</em>-nitro compound that is nitrobenzene in which every hydrogen has been replaced by a chlorine. A fungicide used on a variety of crops, including cotton, rice and seed grains, it is no longer approved for use within the European Union." []
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:83390 ! pentachlorobenzenes
is_a: CHEBI:87034 ! aromatic fungicide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:34911
name: permethrin
def: "A cyclopropanecarboxylate ester in which the esterifying alcohol is 3-phenoxybenzyl alcohol and the cyclopropane ring is substituted with a 2,2-dichlorovinyl group and with <em>gem</em>-dimethyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:38956 ! has role ectoparasiticide
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0000087 CHEBI:39259 ! has role pyrethroid ester acaricide
relationship: RO:0000087 CHEBI:73333 ! has role scabicide
relationship: RO:0018038 CHEBI:39308 ! has functional parent 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid

[Term]
id: CHEBI:34914
name: phenolphthalein
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35259 ! benzofurans
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0018038 CHEBI:38085 ! has functional parent 2-benzofuran-1(3H)-one

[Term]
id: CHEBI:34916
name: phenothrin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0018038 CHEBI:3680 ! has functional parent chrysanthemic acid

[Term]
id: CHEBI:34922
name: picloram
def: "A pyridinemonocarboxylic acid that is pyridine-2-carboxylic acid which is substituted by a chloro group at positions 3,5 and 6, and by an amino group at position 4. It is a systemic herbicide used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops." []
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
is_a: CHEBI:38207 ! aminopyridine
is_a: CHEBI:38656 ! organochlorine pesticide
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0018038 CHEBI:28747 ! has functional parent picolinic acid

[Term]
id: CHEBI:3493
name: cefoperazone
def: "A semi-synthetic parenteral cephalosporin with a tetrazolyl moiety that confers beta-lactamase resistance." []
is_a: CHEBI:23066 ! cephalosporin
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug

[Term]
id: CHEBI:34934
name: prometon
def: "A  methoxy-1,3,5-triazine that is 6-methoxy-1,3,5-triazine-2,4-diamine in which the one of the hydrogens of each amino group is substituted by an isopropyl group." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38930 ! has functional parent 6-methoxy-1,3,5-triazine-2,4-diamine

[Term]
id: CHEBI:34935
name: propyzamide
def: "A member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of in a wide variety of fruit and root crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:73477 ! terminal acetylenic compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:34938
name: propoxur
def: "A carbamate ester that is phenyl methylcarbamate substituted at position 2 by a propan-2-yloxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38461 ! has role carbamate insecticide
relationship: RO:0018038 CHEBI:38547 ! has functional parent 2-isopropoxyphenol
relationship: RO:0018038 CHEBI:45379 ! has functional parent methylcarbamic acid

[Term]
id: CHEBI:34956
name: ruthenium red
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35733 ! ruthenium coordination entity
relationship: RO:0000087 CHEBI:139361 ! has role TRP channel blocker
relationship: RO:0000087 CHEBI:38809 ! has role ryanodine receptor modulator

[Term]
id: CHEBI:35005
name: tetrachlorvinphos
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:25705 ! organochlorine insecticide
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:37494 ! alkenyl phosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38961 ! has functional parent 1-phenylethenol

[Term]
id: CHEBI:35006
name: Tetracycline hydrochloride
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:35008
name: tetralin
def: "An <em>ortho</em>-fused bicyclic hydrocarbon that is 1,2,3,4-tetrahydro derivative of naphthalene." []
is_a: CHEBI:35428 ! ortho-fused bicyclic hydrocarbon
is_a: CHEBI:36786 ! tetralins
relationship: RO:0018040 CHEBI:16482 ! has parent hydride naphthalene

[Term]
id: CHEBI:35011
name: Thiobencarb
is_a: CHEBI:38128 ! monothiocarbamic ester
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:35019
name: tributyl phosphate
def: "A trialkyl phosphate that is the tributyl ester of phosphoric acid." []
is_a: CHEBI:37562 ! trialkyl phosphate

[Term]
id: CHEBI:35026
name: triethylamine
def: "A tertiary amine that is ammonia in which each hydrogen atom is substituted by an ethyl group." []
is_a: CHEBI:32876 ! tertiary amine

[Term]
id: CHEBI:35027
name: trifluralin
def: "A substituted aniline that is <em>N</em>,<em>N</em>-dipropylaniline substituted by a nitro groups at positions 2 and 6 and a trifluoromethyl group at position 4. It is an agrochemical used as a pre-emergence herbicide." []
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:35033
name: triphenyl phosphate
def: "An  aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq. of phenol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36943 ! aryl phosphate
relationship: RO:0000087 CHEBI:79056 ! has role plasticiser
relationship: RO:0000087 CHEBI:79314 ! has role flame retardant
relationship: RO:0018038 CHEBI:15882 ! has functional parent phenol

[Term]
id: CHEBI:35036
name: fentin chloride
def: "An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a chloro group.  A fungicide used to control blights on potatoes, leaf spot diseases on sugar beet and anthracnose on beans." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23117 ! chlorine molecular entity
is_a: CHEBI:25717 ! organotin compound
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:30537 ! has functional parent triphenylstannane

[Term]
id: CHEBI:35038
name: tris(2-butoxyethyl) phosphate
def: "A trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37562 ! trialkyl phosphate
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:79314 ! has role flame retardant

[Term]
id: CHEBI:350546
name: serotonin(1+)
def: "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:28790 ! is protonated form of serotonin

[Term]
id: CHEBI:35060
name: alpha-Methylstyrene
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:3508
name: ceftazidime
def: "A third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2<i>Z</i>)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton." []
is_a: CHEBI:23066 ! cephalosporin
is_a: CHEBI:36816 ! oxime O-ether
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:50696 ! has role EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
relationship: RO:0018034 CHEBI:53676 ! is protonated form of ceftazidime(1-)

[Term]
id: CHEBI:35104
name: strontium(2+)
synonym: "Strontium" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:39129 ! strontium cation
is_a: CHEBI:60240 ! divalent metal cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:35106
name: nitrogen hydride
is_a: CHEBI:35881 ! pnictogen hydride
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:35107
name: azane
def: "Saturated acyclic nitrogen hydrides having the general formula N<small><sub><em>n</em></sub></small>H<small><sub><em>n</em>+2</sub></small>." []
is_a: CHEBI:35106 ! nitrogen hydride

[Term]
id: CHEBI:35113
name: elemental mercury
is_a: CHEBI:25196 ! mercury molecular entity

[Term]
id: CHEBI:35115
name: elemental manganese
is_a: CHEBI:25154 ! manganese molecular entity

[Term]
id: CHEBI:35117
name: manganese coordination entity
is_a: CHEBI:25154 ! manganese molecular entity
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:35131
name: aldose phosphate
is_a: CHEBI:33447 ! phospho sugar

[Term]
id: CHEBI:35149
name: magnesium hydroxide
is_a: CHEBI:25108 ! magnesium molecular entity
is_a: CHEBI:33989 ! alkaline earth hydroxide

[Term]
id: CHEBI:35150
name: calcium hydroxide
is_a: CHEBI:190295 ! inorganic calcium salt
is_a: CHEBI:22985 ! calcium molecular entity
is_a: CHEBI:33989 ! alkaline earth hydroxide

[Term]
id: CHEBI:35155
name: elemental calcium
is_a: CHEBI:22985 ! calcium molecular entity

[Term]
id: CHEBI:35156
name: calcium salt
is_a: CHEBI:22985 ! calcium molecular entity
is_a: CHEBI:36364 ! alkaline earth salt
relationship: BFO:0000051 CHEBI:29108 ! has part calcium(2+)

[Term]
id: CHEBI:35162
name: acyclic carotene
is_a: CHEBI:23042 ! carotene

[Term]
id: CHEBI:35163
name: cyclic carotene
is_a: CHEBI:23042 ! carotene

[Term]
id: CHEBI:35166
name: vanadium coordination entity
is_a: CHEBI:27275 ! vanadium molecular entity
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:35168
name: hydrogenvanadate
def: "A divalent inorganic anion obtained by removal of two protons from vanadic acid." []
is_a: CHEBI:30528 ! vanadium oxoanion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:35169 ! is deprotonated form of dihydrogenvanadate
relationship: RO:0018034 CHEBI:46442 ! is protonated form of vanadate(3-)

[Term]
id: CHEBI:35169
name: dihydrogenvanadate
def: "A monovalent inorganic anion that consists of vanadic acid where one of the three OH groups has been deprotonated." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:30528 ! vanadium oxoanion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0018033 CHEBI:27273 ! is deprotonated form of vanadic acid
relationship: RO:0018034 CHEBI:35168 ! is protonated form of hydrogenvanadate

[Term]
id: CHEBI:35174
name: vanadium oxide
is_a: CHEBI:133331 ! metal oxide
is_a: CHEBI:27275 ! vanadium molecular entity

[Term]
id: CHEBI:35175
name: sulfate salt
is_a: CHEBI:24866 ! salt
is_a: CHEBI:26820 ! sulfates

[Term]
id: CHEBI:35179
name: 2-oxo monocarboxylic acid anion
def: "An oxo monocarboxylic acid anion in which the oxo group is located at the 2-position." []
is_a: CHEBI:35902 ! oxo monocarboxylic acid anion
relationship: RO:0018033 CHEBI:35910 ! is deprotonated form of 2-oxo monocarboxylic acid

[Term]
id: CHEBI:35186
name: terpene
def: "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH<small><sub>2</sub></small>=C(CH<small><sub>3</sub></small>)CH=CH<small><sub>2</sub></small>]." []
is_a: CHEBI:24632 ! hydrocarbon
is_a: CHEBI:24913 ! isoprenoid

[Term]
id: CHEBI:35187
name: monoterpene
def: "A C<small><sub>10</sub></small> terpene." []
is_a: CHEBI:35186 ! terpene

[Term]
id: CHEBI:35188
name: hemiterpene
def: "A C<small><sub>5</sub></small> terpene." []
is_a: CHEBI:35186 ! terpene

[Term]
id: CHEBI:35189
name: sesquiterpene
def: "A C<small><sub>15</sub></small> terpene." []
is_a: CHEBI:35186 ! terpene

[Term]
id: CHEBI:35190
name: diterpene
def: "A C<small><sub>20</sub></small> terpene." []
is_a: CHEBI:35186 ! terpene

[Term]
id: CHEBI:35191
name: triterpene
def: "A C<small><sub>30</sub></small> terpene." []
is_a: CHEBI:35186 ! terpene

[Term]
id: CHEBI:35193
name: tetraterpene
def: "A C<small><sub>40</sub></small> terpene." []
is_a: CHEBI:35186 ! terpene

[Term]
id: CHEBI:35194
name: isoprene
def: "A hemiterpene with the formula CH<small><sub>2</sub></small>=C(CH<small><sub>3</sub></small>)CH=CH<small><sub>2</sub></small>; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:33646 ! alkadiene
is_a: CHEBI:35188 ! hemiterpene
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:35195
name: surfactant
def: "A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces." []
is_a: CHEBI:63046 ! emulsifier

[Term]
id: CHEBI:35196
name: nitrogen oxide
is_a: CHEBI:24836 ! inorganic oxide
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:35202
name: molybdenum coordination entity
is_a: CHEBI:25370 ! molybdenum molecular entity
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:35204
name: tracer
def: "A role played by a foreign substance mixed with or attached to a given substance to enable the distribution or location of the latter to be determined subsequently." []
is_a: CHEBI:33232 ! application
relationship: BFO:0000051 CHEBI:35209 ! has part label

[Term]
id: CHEBI:35208
name: physical tracer
def: "A physical tracer is one that is attached by physical means to the object being traced." []
is_a: CHEBI:35204 ! tracer

[Term]
id: CHEBI:35209
name: label
def: "A role played by a part of a molecular entity distinguishable by the observer but not by the system and used to identify a tracer." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:35213
name: cyclodepsipeptide
def: "A depsipeptide in which the amino and hydroxy carboxylic acid residues are connected in a ring." []
is_a: CHEBI:23643 ! depsipeptide
is_a: CHEBI:25000 ! lactone

[Term]
id: CHEBI:35218
name: anthocyanin cation
def: "Any flavonoid that is a glycoside derivative of an anthocyanidin cation." []
is_a: CHEBI:24400 ! glycoside
is_a: CHEBI:47916 ! flavonoid
relationship: RO:0018038 CHEBI:16366 ! has functional parent anthocyanidin cation

[Term]
id: CHEBI:35219
name: plant growth retardant
is_a: CHEBI:26155 ! plant growth regulator

[Term]
id: CHEBI:35221
name: antimetabolite
def: "A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:35222
name: inhibitor
def: "A substance that diminishes the rate of a chemical reaction." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:35223
name: catalyst
def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:35224
name: effector
def: "A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site)." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:35227
name: 4-nitrotoluene
def: "A mononitrotoluene that consists of toluene bearing a nitro substituent at the 4-position." []
synonym: "1-Methyl-4-nitrobenzene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:63171 ! mononitrotoluene

[Term]
id: CHEBI:35230
name: fossil fuel
def: "A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth." []
is_a: CHEBI:33292 ! fuel

[Term]
id: CHEBI:35235
name: L-cysteine zwitterion
is_a: CHEBI:35237 ! cysteine zwitterion
relationship: RO:0018033 CHEBI:32445 ! is deprotonated form of L-cysteinium
relationship: RO:0018034 CHEBI:32442 ! is protonated form of L-cysteinate(1-)
relationship: RO:0018036 CHEBI:17561 ! is tautomer of L-cysteine
relationship: RO:0018039 CHEBI:35236 ! is enantiomer of D-cysteine zwitterion

[Term]
id: CHEBI:35236
name: D-cysteine zwitterion
is_a: CHEBI:35237 ! cysteine zwitterion
relationship: RO:0018033 CHEBI:32451 ! is deprotonated form of D-cysteinium
relationship: RO:0018034 CHEBI:32449 ! is protonated form of D-cysteinate(1-)
relationship: RO:0018036 CHEBI:16375 ! is tautomer of D-cysteine
relationship: RO:0018039 CHEBI:35235 ! is enantiomer of L-cysteine zwitterion

[Term]
id: CHEBI:35237
name: cysteine zwitterion
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018033 CHEBI:32458 ! is deprotonated form of cysteinium
relationship: RO:0018034 CHEBI:32456 ! is protonated form of cysteinate(1-)
relationship: RO:0018036 CHEBI:15356 ! is tautomer of cysteine

[Term]
id: CHEBI:35238
name: amino-acid zwitterion
def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." []
is_a: CHEBI:27369 ! zwitterion

[Term]
id: CHEBI:35243
name: serine zwitterion
def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of serine." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:17822 ! is tautomer of serine

[Term]
id: CHEBI:35247
name: D-serine zwitterion
def: "A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of <small>D</small>-serine." []
is_a: CHEBI:35243 ! serine zwitterion
relationship: RO:0018036 CHEBI:16523 ! is tautomer of D-serine
relationship: RO:0018039 CHEBI:33384 ! is enantiomer of L-serine zwitterion

[Term]
id: CHEBI:35255
name: chloroform
def: "A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines." []
synonym: "Chloroform" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23148 ! chloromethanes
relationship: RO:0000087 CHEBI:35470 ! has role central nervous system drug
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:35259
name: benzofurans
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:35267
name: quaternary ammonium ion
def: "A derivative of ammonium, NH<small><sub>4</sub></small><small><sup>+</small></sup>, in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative

[Term]
id: CHEBI:35273
name: quaternary ammonium salt
def: "Derivatives of ammonium compounds, (NH<small><sub>4</sub></small><small><sup>+</small></sup>)Y<small><sup>−</small></sup>, in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." []
is_a: CHEBI:26469 ! quaternary nitrogen compound
is_a: CHEBI:46850 ! organoammonium salt

[Term]
id: CHEBI:35274
name: ammonium ion derivative
def: "A derivative of ammonium, NH<small><sub>4</sub></small><small><sup>+</small></sup>, in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." []
is_a: CHEBI:33702 ! polyatomic cation
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: RO:0018040 CHEBI:28938 ! has parent hydride ammonium

[Term]
id: CHEBI:35275
name: S-glycosyl compound
def: "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and a S atom bound to a carbon atom, thus creating a C-S bond." []
is_a: CHEBI:59793 ! monothioacetal
is_a: CHEBI:63161 ! glycosyl compound
is_a: CHEBI:73754 ! thiosugar

[Term]
id: CHEBI:35276
name: ammonium compound
def: "Compounds (NH<small><sub>4</sub></small><small><sup>+</small></sup>)Y<small><sup>−</small></sup> and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups." []
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: BFO:0000051 CHEBI:35274 ! has part ammonium ion derivative

[Term]
id: CHEBI:35281
name: onium betaine
def: "Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom." []
is_a: CHEBI:27369 ! zwitterion

[Term]
id: CHEBI:35284
name: ammonium betaine
def: "Any neutral molecule having charge-separated forms with a quaternary ammonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom." []
is_a: CHEBI:26469 ! quaternary nitrogen compound
is_a: CHEBI:35281 ! onium betaine

[Term]
id: CHEBI:35286
name: iminium ion
def: "Cations of structure R<small><sub>2</sub></small>C=N<small><sup>+</small></sup>R<small><sub>2</sub></small>." []
is_a: CHEBI:25697 ! organic cation

[Term]
id: CHEBI:35287
name: acylcholine
def: "A choline ester formed from choline and a carboxylic acid." []
is_a: CHEBI:35267 ! quaternary ammonium ion

[Term]
id: CHEBI:35290
name: 1,2-dichlorobenzene
def: "A dichlorobenzene carrying chloro substituents at positions 1 and 2." []
synonym: "1,2-Dichlorobenzene" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23697 ! dichlorobenzene
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent

[Term]
id: CHEBI:35291
name: all-trans-retinoate
def: "A retinoate that is the conjugate base of <i>all</i>-<i>trans</i>-retinoic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15036 ! retinoate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15367 ! is deprotonated form of all-trans-retinoic acid

[Term]
id: CHEBI:35293
name: fused compound
def: "A polycyclic compound that contains more than one ring with at least two common atoms (also known as bridgehead carbons) that are adjacent to each other." []
is_a: CHEBI:33635 ! polycyclic compound

[Term]
id: CHEBI:35294
name: carbopolycyclic compound
def: "A polyclic compound in which all of the ring members are carbon atoms." []
is_a: CHEBI:33598 ! carbocyclic compound
is_a: CHEBI:35295 ! homopolycyclic compound

[Term]
id: CHEBI:35295
name: homopolycyclic compound
is_a: CHEBI:33597 ! homocyclic compound
is_a: CHEBI:33635 ! polycyclic compound

[Term]
id: CHEBI:35296
name: ortho-fused polycyclic arene
is_a: CHEBI:33848 ! polycyclic arene
is_a: CHEBI:35427 ! ortho-fused polycyclic hydrocarbon

[Term]
id: CHEBI:35297
name: acene
def: "A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement." []
is_a: CHEBI:35296 ! ortho-fused polycyclic arene
is_a: CHEBI:51269 ! acenes

[Term]
id: CHEBI:35298
name: anthracene
def: "An <em>ortho</em>-fused tricyclic hydrocarbon comprising three fused benzene rings." []
synonym: "ANTHRACENE" EXACT [PDBeChem]
synonym: "Anthracene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35297 ! acene
is_a: CHEBI:37089 ! ortho-fused tricyclic hydrocarbon
is_a: CHEBI:46955 ! anthracenes

[Term]
id: CHEBI:35300
name: ortho- and peri-fused polycyclic arene
is_a: CHEBI:33639 ! ortho- and peri-fused compound
is_a: CHEBI:33848 ! polycyclic arene

[Term]
id: CHEBI:35310
name: carotenone
is_a: CHEBI:27325 ! xanthophyll

[Term]
id: CHEBI:35312
name: pentoside
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:35313
name: hexoside
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:35314
name: glycosiduronic acid
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:35315
name: deoxy hexoside
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:35324
name: hydrazinium(1+)
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018033 CHEBI:35325 ! is deprotonated form of hydrazinium(2+)
relationship: RO:0018034 CHEBI:15571 ! is protonated form of hydrazine

[Term]
id: CHEBI:35325
name: hydrazinium(2+)
is_a: CHEBI:35106 ! nitrogen hydride
relationship: RO:0018034 CHEBI:35324 ! is protonated form of hydrazinium(1+)

[Term]
id: CHEBI:35337
name: central nervous system stimulant
def: "Any drug that enhances the activity of the central nervous system." []
is_a: CHEBI:35470 ! central nervous system drug

[Term]
id: CHEBI:35338
name: amphetamines
def: "Amines that constitute a class of central nervous system stimulants based on the structure of the parent amphetamine 1-phenylpropan-2-amine." []
is_a: CHEBI:32952 ! amine
relationship: RO:0000087 CHEBI:35337 ! has role central nervous system stimulant

[Term]
id: CHEBI:35340
name: methamphetamine hydrochloride
def: "A hydrochloride having methamphetamine as the base component." []
is_a: CHEBI:35338 ! amphetamines
is_a: CHEBI:36807 ! hydrochloride
relationship: BFO:0000051 CHEBI:132297 ! has part methamphetamine(1+)

[Term]
id: CHEBI:35341
name: steroid
def: "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[<em>a</em>]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:35342
name: 17alpha-hydroxy steroid
def: "The α-stereoisomer of 17-hydroxy steroid." []
is_a: CHEBI:36838 ! 17-hydroxy steroid

[Term]
id: CHEBI:35343
name: 17beta-hydroxy steroid
def: "A 17-hydroxy steroid in which the hydroxy group at position 17 has a β-configuration." []
is_a: CHEBI:36838 ! 17-hydroxy steroid

[Term]
id: CHEBI:35344
name: 21-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:35346
name: 11beta-hydroxy steroid
def: "Any 11-hydroxy steroid in which the hydroxy group at position 11 has β- configuration." []
is_a: CHEBI:36841 ! 11-hydroxy steroid

[Term]
id: CHEBI:35348
name: 3beta-sterol
def: "A sterol in which the hydroxy group at position 3 has β- configuration." []
is_a: CHEBI:15889 ! sterol
is_a: CHEBI:36836 ! 3beta-hydroxy steroid

[Term]
id: CHEBI:35350
name: hydroxy steroid
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:35352
name: organonitrogen compound
def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." []
is_a: CHEBI:33285 ! heteroorganic entity
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:35356
name: dicarboximide
def: "An imide in which the two acyl substituents on nitrogen are carboacyl groups." []
is_a: CHEBI:24782 ! imide

[Term]
id: CHEBI:35358
name: sulfonamide
def: "An amide of a sulfonic acid RS(=O)<small><sub>2</sub></small>NR'<small><sub>2</sub></small>." []
is_a: CHEBI:33256 ! primary amide
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:33552 ! sulfonic acid derivative

[Term]
id: CHEBI:35359
name: carboxamidine
def: "Compounds having the structure RC(=NR)NR<small><sub>2</sub></small>. The term is used as a suffix in systematic nomenclature to denote the ‒C(=NH)NH<small><sub>2</sub></small> group including its carbon atom." []
is_a: CHEBI:2634 ! amidine
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:35362
name: hydrazide
def: "Compounds derived from oxoacids R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> ≠ 0) by replacing ‒OH  by ‒NRNR<small><sub>2</sub></small> (R groups are commonly H). (IUPAC)." []
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:35363
name: carbohydrazide
def: "A hydrazide consisting of hydrazine carrying one or more carboacyl groups." []
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:35362 ! hydrazide

[Term]
id: CHEBI:35366
name: fatty acid
def: "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0018034 CHEBI:28868 ! is protonated form of fatty acid anion

[Term]
id: CHEBI:35367
name: thiocarboxylic acid anion
is_a: CHEBI:25696 ! organic anion

[Term]
id: CHEBI:35381
name: monosaccharide
def: "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]<small><sub><em>n</em></sub></small>C(=O)H or polyhydroxy ketones H‒[CHOH]<small><sub><em>n</em></sub></small>‒C(=O)[CHOH]<small><sub><em>m</em></sub></small>‒H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." []
is_a: CHEBI:16646 ! carbohydrate

[Term]
id: CHEBI:35391
name: aspartate(1-)
def: "An α-amino-acid anion that is the conjugate base of aspartic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132943 ! aspartate
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:29995 ! is protonated form of aspartate(2-)

[Term]
id: CHEBI:35397
name: DL-tartrate(1-)
def: "A racemate comprising equimolar amounts of <small>D</small>- and <small>L</small>-tartrate(1−)." []
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:35398 ! has part L-tartrate(1-)
relationship: BFO:0000051 CHEBI:35399 ! has part D-tartrate(1-)
relationship: RO:0018033 CHEBI:26849 ! is deprotonated form of DL-tartaric acid
relationship: RO:0018034 CHEBI:15193 ! is protonated form of DL-tartrate(2-)

[Term]
id: CHEBI:35398
name: L-tartrate(1-)
is_a: CHEBI:48929 ! 3-carboxy-2,3-dihydroxypropanoate
relationship: RO:0018033 CHEBI:15671 ! is deprotonated form of L-tartaric acid
relationship: RO:0018034 CHEBI:30924 ! is protonated form of L-tartrate(2-)
relationship: RO:0018039 CHEBI:35399 ! is enantiomer of D-tartrate(1-)

[Term]
id: CHEBI:35399
name: D-tartrate(1-)
is_a: CHEBI:48929 ! 3-carboxy-2,3-dihydroxypropanoate
relationship: RO:0018033 CHEBI:15672 ! is deprotonated form of D-tartaric acid
relationship: RO:0018034 CHEBI:30927 ! is protonated form of D-tartrate(2-)
relationship: RO:0018039 CHEBI:35398 ! is enantiomer of L-tartrate(1-)

[Term]
id: CHEBI:3540
name: cephalotaxine
def: "A benzazepine alkaloid isolated from <em>Cephalotaxus harringtonia</em>." []
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:38523 ! benzazepine alkaloid
is_a: CHEBI:38527 ! benzazepine alkaloid fundamental parent
is_a: CHEBI:47985 ! enol ether
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:59770 ! cyclic acetal

[Term]
id: CHEBI:35401
name: chromium oxoacid
is_a: CHEBI:35403 ! chromium coordination entity
is_a: CHEBI:36265 ! transition element oxoacid

[Term]
id: CHEBI:35402
name: chromium oxoanion
is_a: CHEBI:35403 ! chromium coordination entity
is_a: CHEBI:35405 ! transition element oxoanion

[Term]
id: CHEBI:35403
name: chromium coordination entity
is_a: CHEBI:23237 ! chromium molecular entity
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:35404
name: chromate(2-)
def: "A chromium oxoanion resulting from the removal of two protons from chromic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35402 ! chromium oxoanion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent
relationship: RO:0018033 CHEBI:33144 ! is deprotonated form of hydrogenchromate

[Term]
id: CHEBI:35405
name: transition element oxoanion
is_a: CHEBI:24834 ! inorganic anion
is_a: CHEBI:33861 ! transition element coordination entity
is_a: CHEBI:35406 ! oxoanion

[Term]
id: CHEBI:35406
name: oxoanion
def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." []
is_a: CHEBI:25741 ! oxide
is_a: CHEBI:33273 ! polyatomic anion

[Term]
id: CHEBI:35410
name: primary diamine
def: "A primary diamine is a compound derived from a hydrocarbon by replacing two hydrogen atoms by amino groups." []
is_a: CHEBI:23666 ! diamine

[Term]
id: CHEBI:35411
name: alkane-alpha,omega-diamine
def: "A primary diamine that is ethane or a higher alkane in which a hydrogen of each of the terminal methyl groups has been replaced by an amino group. H<small><sub>2</sub></small>NCH<small><sub>2</sub></small>(CH<small><sub>2</sub></small>)<small><sub>n</sub></small>CH<small><sub>2</sub></small>NH<small><sub>2</sub></small>, where n = 0, 1, 2, etc." []
is_a: CHEBI:35410 ! primary diamine
is_a: CHEBI:46687 ! diazaalkane
relationship: RO:0018033 CHEBI:70977 ! is deprotonated form of alkane-alpha,omega-diammonium(2+)

[Term]
id: CHEBI:35426
name: ortho-fused bicyclic arene
is_a: CHEBI:35296 ! ortho-fused polycyclic arene
is_a: CHEBI:35428 ! ortho-fused bicyclic hydrocarbon

[Term]
id: CHEBI:35427
name: ortho-fused polycyclic hydrocarbon
is_a: CHEBI:33637 ! ortho-fused compound

[Term]
id: CHEBI:35428
name: ortho-fused bicyclic hydrocarbon
is_a: CHEBI:33637 ! ortho-fused compound
is_a: CHEBI:36785 ! carbobicyclic compound

[Term]
id: CHEBI:35436
name: D-glucoside
def: "Any glucoside in which the glycoside group is derived from <small>D</small>-glucose." []
is_a: CHEBI:24278 ! glucoside

[Term]
id: CHEBI:35438
name: nickel coordination entity
is_a: CHEBI:33748 ! nickel molecular entity

[Term]
id: CHEBI:35441
name: antiinfective agent
def: "A substance used in the prophylaxis or therapy of infectious diseases." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35442
name: antiparasitic agent
def: "A substance used to treat or prevent parasitic infections." []
is_a: CHEBI:35441 ! antiinfective agent

[Term]
id: CHEBI:35443
name: anthelminthic drug
def: "Substance intended to kill parasitic worms (helminths)." []
is_a: CHEBI:35442 ! antiparasitic agent

[Term]
id: CHEBI:35444
name: antinematodal drug
def: "A substance used in the treatment or control of nematode infestations." []
is_a: CHEBI:25491 ! nematicide
is_a: CHEBI:35443 ! anthelminthic drug

[Term]
id: CHEBI:35445
name: 3,3',5,5'-tetrachlorobiphenyl
def: "A tetrachlorobiphenyl that is biphenyl in which both phenyl groups are substituted by chlorines at positions 3 and 5." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl

[Term]
id: CHEBI:35446
name: chlorobiphenyl
def: "A chloroarene that consists of a biphenyl skeleton substituted by one or more chloro groups." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:36686 ! chloroarene

[Term]
id: CHEBI:35456
name: cadmium dichloride
def: "A cadmium coordination entity in which cadmium(2+) and Cl<small><sup>−</small></sup> ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding." []
is_a: CHEBI:36565 ! cadmium coordination entity

[Term]
id: CHEBI:35457
name: EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
def: "An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1)." []
is_a: CHEBI:35674 ! antihypertensive agent
is_a: CHEBI:76782 ! EC 3.4.15.* (peptidyl-dipeptidase) inhibitor

[Term]
id: CHEBI:35467
name: phosphorodiamide
is_a: CHEBI:17102 ! phosphoramide

[Term]
id: CHEBI:35468
name: triazene
is_a: CHEBI:35106 ! nitrogen hydride

[Term]
id: CHEBI:35469
name: antidepressant
def: "Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions." []
is_a: CHEBI:35471 ! psychotropic drug

[Term]
id: CHEBI:35470
name: central nervous system drug
def: "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35471
name: psychotropic drug
def: "A loosely defined grouping of drugs that have effects on psychological function." []
is_a: CHEBI:35470 ! central nervous system drug

[Term]
id: CHEBI:35472
name: anti-inflammatory drug
def: "A substance that reduces or suppresses inflammation." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:67079 ! anti-inflammatory agent

[Term]
id: CHEBI:35473
name: tranquilizing drug
def: "A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour." []
is_a: CHEBI:35471 ! psychotropic drug
is_a: CHEBI:35488 ! central nervous system depressant

[Term]
id: CHEBI:35474
name: anxiolytic drug
def: "Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions." []
is_a: CHEBI:35473 ! tranquilizing drug

[Term]
id: CHEBI:35475
name: non-steroidal anti-inflammatory drug
def: "An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins." []
is_a: CHEBI:35472 ! anti-inflammatory drug
is_a: CHEBI:35842 ! antirheumatic drug

[Term]
id: CHEBI:35476
name: antipsychotic agent
def: "Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect." []
is_a: CHEBI:35473 ! tranquilizing drug

[Term]
id: CHEBI:35477
name: antimanic drug
def: "Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders." []
is_a: CHEBI:35473 ! tranquilizing drug

[Term]
id: CHEBI:35478
name: lithium salt
is_a: CHEBI:33298 ! lithium molecular entity
is_a: CHEBI:35479 ! alkali metal salt

[Term]
id: CHEBI:35479
name: alkali metal salt
is_a: CHEBI:24866 ! salt
is_a: CHEBI:33296 ! alkali metal molecular entity

[Term]
id: CHEBI:35480
name: analgesic
def: "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:35481
name: non-narcotic analgesic
def: "A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors." []
is_a: CHEBI:35480 ! analgesic

[Term]
id: CHEBI:35482
name: opioid analgesic
def: "A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood." []
is_a: CHEBI:35480 ! analgesic

[Term]
id: CHEBI:35484
name: phthalate ester
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:62732 ! aromatic ester
relationship: RO:0000087 CHEBI:138015 ! has role endocrine disruptor
relationship: RO:0018038 CHEBI:29069 ! has functional parent phthalic acid

[Term]
id: CHEBI:35486
name: maleate ester
def: "Compounds of the general formula ROOC-CH=CH-COOR' where R and R' are organyl groups" []
is_a: CHEBI:51702 ! enoate ester
relationship: RO:0018038 CHEBI:18300 ! has functional parent maleic acid

[Term]
id: CHEBI:35487
name: EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
def: "An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor) inhibitor that interferes with the action of aldehyde dehydrogenase (NAD<small><sup>+</small></sup>), EC 1.2.1.3." []
is_a: CHEBI:76852 ! EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:35488
name: central nervous system depressant
def: "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." []
is_a: CHEBI:35470 ! central nervous system drug

[Term]
id: CHEBI:35489
name: organic disulfide
def: "Compounds of structure RSSR in which R and R' are organic groups." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:48343 ! disulfide

[Term]
id: CHEBI:35493
name: antipyretic
def: "A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35496
name: fluorobenzenes
def: "Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:35497
name: androgen antagonist
def: "A compound which inhibits or antagonises the biosynthesis or actions of androgens." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:35498
name: diuretic
def: "An agent that promotes the excretion of urine through its effects on kidney function." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35499
name: hallucinogen
def: "Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking." []
is_a: CHEBI:35471 ! psychotropic drug

[Term]
id: CHEBI:35500
name: 1,4-benzodiazepinone
is_a: CHEBI:22720 ! benzodiazepine

[Term]
id: CHEBI:35504
name: addition compound
def: "An addition compound contains two or more simpler compounds that can be packed in a definite ratio into a crystal. The term covers donor-acceptor complexes (adducts) and a variety of lattice compounds." []
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:35505
name: hydrate
def: "An addition compound that contains water in weak chemical combination with another compound." []
is_a: CHEBI:35504 ! addition compound
relationship: BFO:0000051 CHEBI:15377 ! has part water

[Term]
id: CHEBI:35506
name: alkaloid fundamental parent
is_a: CHEBI:35507 ! natural product fundamental parent

[Term]
id: CHEBI:35507
name: natural product fundamental parent
is_a: CHEBI:33245 ! organic fundamental parent

[Term]
id: CHEBI:35508
name: steroid fundamental parent
is_a: CHEBI:35341 ! steroid
is_a: CHEBI:35507 ! natural product fundamental parent

[Term]
id: CHEBI:35509
name: androstane
is_a: CHEBI:35508 ! steroid fundamental parent

[Term]
id: CHEBI:35510
name: aluminium salt
is_a: CHEBI:33620 ! aluminium molecular entity

[Term]
id: CHEBI:35512
name: ergostane
is_a: CHEBI:35508 ! steroid fundamental parent

[Term]
id: CHEBI:35515
name: 5alpha-cholestane
def: "The 5α-stereoisomer of cholestane." []
is_a: CHEBI:35516 ! cholestane

[Term]
id: CHEBI:35516
name: cholestane
is_a: CHEBI:35508 ! steroid fundamental parent

[Term]
id: CHEBI:35517
name: 5beta-cholestane
is_a: CHEBI:35516 ! cholestane

[Term]
id: CHEBI:35519
name: cholane
is_a: CHEBI:35508 ! steroid fundamental parent

[Term]
id: CHEBI:35522
name: beta-adrenergic agonist
def: "An agent that selectively binds to and activates β-adrenergic receptors." []
is_a: CHEBI:37886 ! adrenergic agonist
is_a: CHEBI:48540 ! beta-adrenergic drug

[Term]
id: CHEBI:35523
name: bronchodilator agent
def: "An agent that causes an increase in the expansion of a bronchus or bronchial tubes." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35524
name: sympathomimetic agent
def: "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." []
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:35526
name: hypoglycemic agent
def: "A drug which lowers the blood glucose level." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35530
name: beta-adrenergic antagonist
def: "An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety." []
is_a: CHEBI:37887 ! adrenergic antagonist
is_a: CHEBI:48540 ! beta-adrenergic drug

[Term]
id: CHEBI:35533
name: propanolamine
is_a: CHEBI:22478 ! amino alcohol

[Term]
id: CHEBI:35542
name: 5beta-cardanolide
is_a: CHEBI:35543 ! cardanolide

[Term]
id: CHEBI:35543
name: cardanolide
is_a: CHEBI:26766 ! steroid lactone
is_a: CHEBI:35508 ! steroid fundamental parent

[Term]
id: CHEBI:35544
name: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
def: "A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes." []
is_a: CHEBI:76840 ! EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

[Term]
id: CHEBI:35545
name: bipyridine
is_a: CHEBI:50511 ! bipyridines

[Term]
id: CHEBI:35546
name: perfluorodecanoic acid
def: "A fluoroalkanoic acid that is perfluorinated decanoic acid." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:30813 ! has functional parent decanoic acid

[Term]
id: CHEBI:35547
name: perfluoroheptanoic acid
def: "A fluoroalkanoic acid that is perfluorinated heptanoic acid." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38847 ! has functional parent perfluoroheptane
relationship: RO:0018038 CHEBI:45571 ! has functional parent heptanoic acid

[Term]
id: CHEBI:35549
name: perfluorooctanoic acid
def: "A fluoroalkanoic acid that is perfluorinated octanoic acid." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:138015 ! has role endocrine disruptor
relationship: RO:0000087 CHEBI:35195 ! has role surfactant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:28837 ! has functional parent octanoic acid
relationship: RO:0018038 CHEBI:38826 ! has functional parent perfluorooctane

[Term]
id: CHEBI:35550
name: 1H-1,2,4-triazole
is_a: CHEBI:35560 ! 1,2,4-triazole
relationship: RO:0018036 CHEBI:35561 ! is tautomer of 3H-1,2,4-triazole
relationship: RO:0018036 CHEBI:46077 ! is tautomer of 4H-1,2,4-triazole

[Term]
id: CHEBI:35551
name: fluoroalkanoic acid
def: "Any organofluorine compound that is the perfluorinated derivative of any alkanoic acid." []
is_a: CHEBI:134091 ! perfluorinated compound
is_a: CHEBI:25384 ! monocarboxylic acid

[Term]
id: CHEBI:35552
name: heterocyclic organic fundamental parent
is_a: CHEBI:33245 ! organic fundamental parent

[Term]
id: CHEBI:35554
name: cardiovascular drug
def: "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35555
name: mancude organic heteromonocyclic parent
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:35571 ! mancude organic heterocyclic parent

[Term]
id: CHEBI:35556
name: pyrrole
def: "A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'." []
is_a: CHEBI:26455 ! pyrroles
is_a: CHEBI:35555 ! mancude organic heteromonocyclic parent

[Term]
id: CHEBI:35557
name: 3H-pyrrole
def: "That one of the three tautomers of pyrrole which has the double bonds at positions 1 and 4." []
is_a: CHEBI:35556 ! pyrrole
relationship: RO:0018036 CHEBI:19203 ! is tautomer of 1H-pyrrole
relationship: RO:0018036 CHEBI:35558 ! is tautomer of 2H-pyrrole

[Term]
id: CHEBI:35558
name: 2H-pyrrole
def: "That one of the three tautomers of pyrrole which has the double bonds at positions 1 and 3." []
is_a: CHEBI:35556 ! pyrrole
relationship: RO:0018036 CHEBI:19203 ! is tautomer of 1H-pyrrole
relationship: RO:0018036 CHEBI:35557 ! is tautomer of 3H-pyrrole

[Term]
id: CHEBI:35559
name: furan
def: "A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C<small><sub>4</sub></small>H<small><sub>4</sub></small>O. It is a toxic, flammable, low-boiling (31°C) colourless liquid." []
synonym: "Furan" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24129 ! furans
is_a: CHEBI:35555 ! mancude organic heteromonocyclic parent
is_a: CHEBI:38179 ! monocyclic heteroarene
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:77523 ! has role Maillard reaction product

[Term]
id: CHEBI:35560
name: 1,2,4-triazole
is_a: CHEBI:38597 ! triazole

[Term]
id: CHEBI:35561
name: 3H-1,2,4-triazole
is_a: CHEBI:35560 ! 1,2,4-triazole
relationship: RO:0018036 CHEBI:35550 ! is tautomer of 1H-1,2,4-triazole
relationship: RO:0018036 CHEBI:46077 ! is tautomer of 4H-1,2,4-triazole

[Term]
id: CHEBI:35568
name: mancude ring
def: "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds." []
is_a: CHEBI:23367 ! molecular entity

[Term]
id: CHEBI:35569
name: alpha-adrenergic agonist
def: "An agent that selectively binds to and activates α-adrenergic receptors." []
is_a: CHEBI:37886 ! adrenergic agonist
is_a: CHEBI:48539 ! alpha-adrenergic drug

[Term]
id: CHEBI:35570
name: mancude organic heterobicyclic parent
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:35571 ! mancude organic heterocyclic parent

[Term]
id: CHEBI:35571
name: mancude organic heterocyclic parent
is_a: CHEBI:35552 ! heterocyclic organic fundamental parent
is_a: CHEBI:35573 ! organic mancude parent

[Term]
id: CHEBI:35573
name: organic mancude parent
is_a: CHEBI:33245 ! organic fundamental parent
is_a: CHEBI:35568 ! mancude ring

[Term]
id: CHEBI:3558
name: cerivastatin
def: "(3<i>R</i>,5<i>S</i>)-3,5-dihydroxyhept-6-enoic acid in which the (7<i>E</i>)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35972 ! dihydroxy monocarboxylic acid
is_a: CHEBI:87635 ! statin (synthetic)
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0018034 CHEBI:406059 ! is protonated form of cerivastatin(1-)

[Term]
id: CHEBI:35580
name: N-oxide
is_a: CHEBI:25741 ! oxide

[Term]
id: CHEBI:35584
name: purine
def: "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26401 ! purines
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:35586
name: 1H-purine
def: "The 1<em>H</em>-tautomer of purine." []
is_a: CHEBI:35584 ! purine
relationship: RO:0018036 CHEBI:17258 ! is tautomer of 7H-purine
relationship: RO:0018036 CHEBI:35588 ! is tautomer of 3H-purine
relationship: RO:0018036 CHEBI:35589 ! is tautomer of 9H-purine

[Term]
id: CHEBI:35588
name: 3H-purine
def: "The 3<em>H</em>-tautomer of purine." []
is_a: CHEBI:35584 ! purine
relationship: RO:0018036 CHEBI:17258 ! is tautomer of 7H-purine
relationship: RO:0018036 CHEBI:35586 ! is tautomer of 1H-purine
relationship: RO:0018036 CHEBI:35589 ! is tautomer of 9H-purine

[Term]
id: CHEBI:35589
name: 9H-purine
def: "The 9<em>H</em>-tautomer of purine." []
is_a: CHEBI:35584 ! purine
relationship: RO:0018036 CHEBI:17258 ! is tautomer of 7H-purine
relationship: RO:0018036 CHEBI:35586 ! is tautomer of 1H-purine
relationship: RO:0018036 CHEBI:35588 ! is tautomer of 3H-purine

[Term]
id: CHEBI:35592
name: 2H-pyran
is_a: CHEBI:35594 ! pyran
relationship: RO:0018036 CHEBI:35593 ! is tautomer of 4H-pyran

[Term]
id: CHEBI:35593
name: 4H-pyran
is_a: CHEBI:35594 ! pyran
relationship: RO:0018036 CHEBI:35592 ! is tautomer of 2H-pyran

[Term]
id: CHEBI:35594
name: pyran
is_a: CHEBI:26407 ! pyrans
is_a: CHEBI:35555 ! mancude organic heteromonocyclic parent

[Term]
id: CHEBI:35601
name: 2H-chromene
def: "A simplest member of the class of chromene in which the heterocyclic pyran ring has a double bond between positions 3 and 4." []
is_a: CHEBI:35602 ! chromene
relationship: RO:0018036 CHEBI:35603 ! is tautomer of 4H-chromene

[Term]
id: CHEBI:35602
name: chromene
is_a: CHEBI:23232 ! chromenes
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent

[Term]
id: CHEBI:35603
name: 4H-chromene
def: "A simplest member of the class of chromene in which the heterocyclic pyran ring has a double bond between positions 2 and 3." []
is_a: CHEBI:35602 ! chromene
relationship: RO:0018036 CHEBI:35601 ! is tautomer of 2H-chromene

[Term]
id: CHEBI:35604
name: carbon oxoanion
def: "A negative ion consisting solely of carbon and oxygen  atoms, and therefore having the general formula C<small><sub><em>x</em></sub></small>O<small><sub><em>y</em></sub></small><small><sup><em>n</em>−</small></sup> for some integers <em>x</em>, <em>y</em> and <em>n</em>." []
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:35406 ! oxoanion
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:35605
name: carbon oxoacid
is_a: CHEBI:24833 ! oxoacid
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:35608
name: EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
def: "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins." []
is_a: CHEBI:76775 ! EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor

[Term]
id: CHEBI:3561
name: cetirizine
def: "A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:25698 ! ether
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:37955 ! has role H1-receptor antagonist
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:35610
name: antineoplastic agent
def: "A substance that inhibits or prevents the proliferation of neoplasms." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35615
name: tropane
is_a: CHEBI:35506 ! alkaloid fundamental parent
is_a: CHEBI:37332 ! tropane alkaloid
is_a: CHEBI:38419 ! saturated organic heterobicyclic parent

[Term]
id: CHEBI:35617
name: flavouring agent
def: "A food additive that is used to added improve the taste or odour of a food." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:35618
name: aromatic ether
def: "Any ether in which the oxygen is attached to at least one aryl substituent." []
is_a: CHEBI:25698 ! ether
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:35620
name: vasodilator agent
def: "A drug used to cause dilation of the blood vessels." []
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:35622
name: thiazolidines
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:35623
name: anticonvulsant
def: "A drug used to prevent seizures or reduce their severity." []
is_a: CHEBI:35488 ! central nervous system depressant

[Term]
id: CHEBI:35624
name: azaspiro compound
def: "An azaspiro compound is a spiro compound in which at least one of the cyclic components is a nitrogen heterocyle." []
is_a: CHEBI:33599 ! spiro compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:35625
name: EC 3.5.2.6 (beta-lactamase) inhibitor
def: "An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of β-lactamase (EC 3.5.2.6)." []
is_a: CHEBI:76808 ! EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor

[Term]
id: CHEBI:35627
name: beta-lactam
def: "A lactam in which the amide bond is contained within a four-membered ring, which includes the amide nitrogen and the carbonyl carbon." []
is_a: CHEBI:24995 ! lactam

[Term]
id: CHEBI:35629
name: naphthylacetic acid
def: "A monocarboxylic acid that is naphthalene substituted by a carboxymethyl group at any position." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:25477 ! naphthalenes
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid
relationship: RO:0018040 CHEBI:16482 ! has parent hydride naphthalene

[Term]
id: CHEBI:35631
name: yohimban
is_a: CHEBI:27358 ! yohimban alkaloid
is_a: CHEBI:38482 ! indole alkaloid fundamental parent

[Term]
id: CHEBI:35633
name: yohimbic acid
is_a: CHEBI:27358 ! yohimban alkaloid
relationship: RO:0018038 CHEBI:35636 ! has functional parent 17alpha-yohimbol

[Term]
id: CHEBI:35634
name: EC 1.17.3.2 (xanthine oxidase) inhibitor
def: "An EC 1.17.3.* (oxidoreductase acting on CH or CH<small><sub>2</sub></small> with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2)." []
is_a: CHEBI:76850 ! EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor

[Term]
id: CHEBI:35636
name: 17alpha-yohimbol
is_a: CHEBI:35637 ! 17-yohimbol

[Term]
id: CHEBI:35637
name: 17-yohimbol
is_a: CHEBI:27358 ! yohimban alkaloid
relationship: RO:0018040 CHEBI:35631 ! has parent hydride yohimban

[Term]
id: CHEBI:35640
name: adrenergic uptake inhibitor
def: "Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin." []
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:35641
name: dibenzannulene
is_a: CHEBI:35296 ! ortho-fused polycyclic arene

[Term]
id: CHEBI:356416
name: 5-ammoniolevulinate
def: "The zwitterion formed from 5-aminolevulinic acid by transfer of a proton from the carboxy group to the amino group.  It is the major species present at physiological pH." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:17549 ! is tautomer of 5-aminolevulinic acid

[Term]
id: CHEBI:35642
name: dibenzo[a,d][7]annulene
is_a: CHEBI:35641 ! dibenzannulene

[Term]
id: CHEBI:35649
name: morphinan
is_a: CHEBI:25418 ! morphinane alkaloid
is_a: CHEBI:38515 ! isoquinoline alkaloid fundamental parent

[Term]
id: CHEBI:35660
name: HIV protease inhibitor
def: "An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly." []
is_a: CHEBI:37670 ! protease inhibitor
is_a: CHEBI:64946 ! anti-HIV agent

[Term]
id: CHEBI:35662
name: terpenoid fundamental parent
is_a: CHEBI:35507 ! natural product fundamental parent

[Term]
id: CHEBI:35664
name: EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
def: "Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:35666
name: thiopurine
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:26401 ! purines

[Term]
id: CHEBI:35674
name: antihypertensive agent
def: "Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism." []
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:35676
name: benzazepine
def: "A group of two-ring heterocyclic compounds consisting of a benzene ring fused to an azepine ring." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:35678
name: histamine agonist
def: "A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically." []
is_a: CHEBI:37957 ! histaminergic drug

[Term]
id: CHEBI:35679
name: antilipemic drug
def: "A substance used to treat hyperlipidemia (an excess of lipids in the blood)." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35681
name: secondary alcohol
def: "A secondary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it." []
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:35682
name: naphthol
def: "A member of the class of naphthols carrying a single hydroxy substituent at C-1 or C-2. A closed class." []
is_a: CHEBI:139520 ! phenolic donor
is_a: CHEBI:25392 ! naphthols
relationship: RO:0018040 CHEBI:16482 ! has parent hydride naphthalene

[Term]
id: CHEBI:35683
name: aryl sulfide
def: "Any organic sulfide in which the sulfur is attached to at least one aromatic group." []
is_a: CHEBI:16385 ! organic sulfide

[Term]
id: CHEBI:35684
name: antiplatyhelmintic drug
def: "An agent used to treat cestode, trematode, or other flatworm infestations in man or animals." []
is_a: CHEBI:35443 ! anthelminthic drug

[Term]
id: CHEBI:35687
name: butan-2-ol
def: "A secondary alcohol that is butane substituted by a hydroxy group at position 2." []
is_a: CHEBI:35681 ! secondary alcohol
relationship: RO:0018040 CHEBI:37808 ! has parent hydride butane

[Term]
id: CHEBI:35688
name: benzimidazolecarboxylic acid
def: "A member of the class of  benzimidazoles carrying a carboxy group at unspecified position." []
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:25384 ! monocarboxylic acid

[Term]
id: CHEBI:35689
name: tetrazoles
def: "An azole in which the five-membered heterocyclic aromatic skeleton contains four N atoms and one C atom." []
is_a: CHEBI:68452 ! azole

[Term]
id: CHEBI:35690
name: cyclobutane-1,1-dicarboxylate(2-)
is_a: CHEBI:36205 ! cyclobutanedicarboxylate
relationship: RO:0018033 CHEBI:35694 ! is deprotonated form of cyclobutane-1,1-dicarboxylate(1-)

[Term]
id: CHEBI:35691
name: cyclobutane-1,1-dicarboxylic acid
is_a: CHEBI:36186 ! cyclobutanedicarboxylic acid
relationship: RO:0018034 CHEBI:35694 ! is protonated form of cyclobutane-1,1-dicarboxylate(1-)

[Term]
id: CHEBI:35692
name: dicarboxylic acid
def: "Any carboxylic acid containing two carboxy groups." []
is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives
is_a: CHEBI:33575 ! carboxylic acid
relationship: RO:0018034 CHEBI:35693 ! is protonated form of dicarboxylic acid anion

[Term]
id: CHEBI:35693
name: dicarboxylic acid anion
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:35692 ! is deprotonated form of dicarboxylic acid

[Term]
id: CHEBI:35694
name: cyclobutane-1,1-dicarboxylate(1-)
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:35691 ! is deprotonated form of cyclobutane-1,1-dicarboxylic acid
relationship: RO:0018034 CHEBI:35690 ! is protonated form of cyclobutane-1,1-dicarboxylate(2-)

[Term]
id: CHEBI:35695
name: dicarboxylic acid monoanion
def: "Any dicarboxylic acid anion that is a monoanion obtained by the deprotonation of only one of the carboxy groups of the dicarboxylic acid." []
is_a: CHEBI:35693 ! dicarboxylic acid anion

[Term]
id: CHEBI:35696
name: cobalt dichloride
def: "A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35698 ! cobalt salt
is_a: CHEBI:36093 ! inorganic chloride
relationship: BFO:0000051 CHEBI:48828 ! has part cobalt(2+)
relationship: RO:0000087 CHEBI:139492 ! has role sensitiser
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:50412 ! has role two-colour indicator
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:35698
name: cobalt salt
is_a: CHEBI:33888 ! cobalt molecular entity

[Term]
id: CHEBI:35701
name: ester
def: "A compound formally derived from an oxoacid R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." []
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:35702
name: diethyl ether
def: "An ether in which the oxygen atom is linked to two ethyl groups." []
synonym: "Ether" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:25698 ! ether
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:35703
name: xenobiotic
def: "A xenobiotic (Greek, <em>xenos</em> \"foreign\"; <em>bios</em> \"life\") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." []
synonym: "Xenobiotic" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:35705
name: immunosuppressive agent
def: "An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response." []
is_a: CHEBI:50846 ! immunomodulator

[Term]
id: CHEBI:35710
name: pinane
def: "A monoterpene that is bicyclo[3.1.1]heptane substituted by methyl groups at positions 2, 6 and 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35187 ! monoterpene
is_a: CHEBI:35662 ! terpenoid fundamental parent
is_a: CHEBI:36785 ! carbobicyclic compound
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:35713
name: polycyclic alkane
def: "A polycyclic saturated hydrocarbon." []
is_a: CHEBI:33666 ! polycyclic hydrocarbon

[Term]
id: CHEBI:35715
name: nitro compound
def: "A compound having a nitro group, ‒NO<small><sub>2</sub></small> (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, <em>C</em>-nitro compounds are usually implied)." []
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: BFO:0000051 CHEBI:29785 ! has part nitro group

[Term]
id: CHEBI:35716
name: C-nitro compound
def: "A nitro compound having the nitro group (‒NO<small><sub>2</sub></small>) attached to a carbon atom." []
is_a: CHEBI:35715 ! nitro compound
is_a: CHEBI:72695 ! organic molecule
relationship: RO:0018036 CHEBI:136622 ! is tautomer of aci-nitro compound

[Term]
id: CHEBI:35717
name: sedative
def: "A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety." []
is_a: CHEBI:35488 ! central nervous system depressant

[Term]
id: CHEBI:35718
name: antifungal agent
def: "An  antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce." []
is_a: CHEBI:33281 ! antimicrobial agent

[Term]
id: CHEBI:35719
name: sulfamic acids
def: "H<small><sub>2</sub></small>NS(=O)<small><sub>2</sub></small>OH (sulfamic acid) and its <em>N</em>-hydrocarbyl derivatives." []
is_a: CHEBI:33552 ! sulfonic acid derivative
relationship: RO:0018034 CHEBI:131822 ! is protonated form of sulfamate

[Term]
id: CHEBI:35720
name: enrofloxacin
def: "A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid substituted by an oxo group at position 4, a fluoro group at position 6, a cyclopropyl group at position 1 and a 4-ethylpiperazin-1-yl group at position 7. It is a veterinary antibacterial agent used for the treatment of pets." []
is_a: CHEBI:23765 ! quinolone
is_a: CHEBI:26512 ! quinolinemonocarboxylic acid
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:46845 ! N-alkylpiperazine
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:51454 ! cyclopropanes
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:35722
name: sulfated glycosaminoglycan
is_a: CHEBI:18085 ! glycosaminoglycan
is_a: CHEBI:35724 ! carbohydrate sulfate

[Term]
id: CHEBI:35724
name: carbohydrate sulfate
is_a: CHEBI:25704 ! organic sulfate
is_a: CHEBI:26819 ! sulfuric ester
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:35725
name: isopropyl ester
def: "Any carboxylic ester resulting from the formal condensation of a carboxylic acid with the hydroxy group of propan-2-ol." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:17824 ! has functional parent propan-2-ol

[Term]
id: CHEBI:35727
name: triazoles
def: "An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms." []
is_a: CHEBI:68452 ! azole

[Term]
id: CHEBI:35731
name: osmium coordination entity
is_a: CHEBI:33861 ! transition element coordination entity
is_a: CHEBI:35732 ! osmium molecular entity

[Term]
id: CHEBI:35732
name: osmium molecular entity
is_a: CHEBI:33744 ! iron group molecular entity
relationship: BFO:0000051 CHEBI:30687 ! has part osmium atom

[Term]
id: CHEBI:35733
name: ruthenium coordination entity
is_a: CHEBI:33861 ! transition element coordination entity
is_a: CHEBI:35734 ! ruthenium molecular entity

[Term]
id: CHEBI:35734
name: ruthenium molecular entity
is_a: CHEBI:33744 ! iron group molecular entity
relationship: BFO:0000051 CHEBI:30682 ! has part ruthenium atom

[Term]
id: CHEBI:35735
name: dicarboxylic acid monoamide
is_a: CHEBI:23690 ! dicarboxylic acid amide
relationship: RO:0018034 CHEBI:77450 ! is protonated form of dicarboxylic acid monoamide(1-)

[Term]
id: CHEBI:35737
name: monothiocarboxylic acid
def: "Compounds in which one oxygen of a carboxy group has been replaced by divalent sulfur; RC(=O)SH or RC(=S)OH." []
is_a: CHEBI:33307 ! thiocarboxylic acid

[Term]
id: CHEBI:35740
name: liposaccharide
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:35741
name: glycerolipid
def: "Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached." []
is_a: CHEBI:18059 ! lipid
relationship: RO:0018038 CHEBI:17754 ! has functional parent glycerol

[Term]
id: CHEBI:35742
name: tetracarboxylic acid
def: "An oxoacid containing four carboxy groups." []
is_a: CHEBI:33575 ! carboxylic acid

[Term]
id: CHEBI:35744
name: carbocyclic fatty acid
def: "Any fatty acid containing a ring composed of carbon atoms." []
is_a: CHEBI:59238 ! cyclic fatty acid
relationship: RO:0018034 CHEBI:157668 ! is protonated form of carbocyclic fatty acid anion

[Term]
id: CHEBI:35746
name: fatty aldehyde
def: "An aldehyde formally arising from reduction of the carboxylic acid group of its corresponding fatty acid, having a carbonyl group at one end of the carbon chain." []
is_a: CHEBI:59768 ! aliphatic aldehyde

[Term]
id: CHEBI:35748
name: fatty acid ester
def: "A carboxylic ester in which the carboxylic acid component can be any fatty acid." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:61697 ! fatty acid derivative

[Term]
id: CHEBI:35753
name: tricarboxylic acid anion
def: "Any anion of a tricarboxylic acid  formed by deprotonation of at least one carboxy group." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:27093 ! is deprotonated form of tricarboxylic acid

[Term]
id: CHEBI:35754
name: tetracarboxylic acid anion
def: "Any anion of a tetracarboxylic acid formed by deprotonation of one or more carboxy groups." []
is_a: CHEBI:29067 ! carboxylic acid anion

[Term]
id: CHEBI:35757
name: monocarboxylic acid anion
def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:25384 ! is deprotonated form of monocarboxylic acid

[Term]
id: CHEBI:35776
name: arsenic oxoanion
is_a: CHEBI:22632 ! arsenic molecular entity
is_a: CHEBI:33459 ! pnictogen oxoanion

[Term]
id: CHEBI:35777
name: boron oxide
is_a: CHEBI:22916 ! boron molecular entity
is_a: CHEBI:24836 ! inorganic oxide

[Term]
id: CHEBI:35779
name: dicarboxylic acid diamide
is_a: CHEBI:23690 ! dicarboxylic acid amide

[Term]
id: CHEBI:35780
name: phosphate ion
def: "A phosphorus oxoanion that is the conjugate base of phosphoric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33461 ! phosphorus oxoanion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:26078 ! is deprotonated form of phosphoric acid

[Term]
id: CHEBI:35782
name: diphosphate ion
is_a: CHEBI:33461 ! phosphorus oxoanion

[Term]
id: CHEBI:35783
name: bornane
is_a: CHEBI:35187 ! monoterpene
is_a: CHEBI:35662 ! terpenoid fundamental parent

[Term]
id: CHEBI:35785
name: sphingoid
def: "Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds." []
is_a: CHEBI:26739 ! sphingolipid
relationship: RO:0018033 CHEBI:83876 ! is deprotonated form of cationic sphingoid

[Term]
id: CHEBI:35788
name: seco-steroid
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:35789
name: oxo steroid
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:35790
name: oxazole
def: "An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom." []
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:68452 ! azole

[Term]
id: CHEBI:35800
name: nitroso compound
def: "Compounds having the nitroso group, ‒NO, attached to carbon, or to another element, most commonly nitrogen or oxygen." []
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: BFO:0000051 CHEBI:35801 ! has part nitroso group

[Term]
id: CHEBI:35801
name: nitroso group
is_a: CHEBI:33246 ! inorganic group
is_a: CHEBI:51144 ! nitrogen group

[Term]
id: CHEBI:35803
name: nitrosamine
def: "<em>N</em>-Nitroso amines, compounds of the structure R<small><sub>2</sub></small>NNO. Compounds RNHNO are not ordinarily isolable, but they, too, are nitrosamines. The name is a contraction of <em>N</em>-nitrosoamine and, as such, does not require the <em>N</em> locant." []
is_a: CHEBI:35800 ! nitroso compound

[Term]
id: CHEBI:35804
name: citrate(1-)
def: "A tricarboxylic acid monoanion that is the conjugate base of citric acid, obtained by deprotonation of one of the three carboxy groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133748 ! citrate anion
is_a: CHEBI:36299 ! tricarboxylic acid monoanion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:35808 ! is protonated form of citrate(2-)

[Term]
id: CHEBI:35807
name: N-nitrosodimethylamine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35803 ! nitrosamine
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:25435 ! has role mutagen

[Term]
id: CHEBI:35808
name: citrate(2-)
def: "A tricarboxylic acid dianion obtained by deprotonation of two of the three carboxy groups of citric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133748 ! citrate anion
is_a: CHEBI:36300 ! tricarboxylic acid dianion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:35804 ! is deprotonated form of citrate(1-)
relationship: RO:0018034 CHEBI:16947 ! is protonated form of citrate(3-)

[Term]
id: CHEBI:35816
name: leprostatic drug
def: "A substance that suppresses <em>Mycobacterium leprae</em>, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions." []
is_a: CHEBI:64912 ! antimycobacterial drug

[Term]
id: CHEBI:35818
name: coccidiostat
def: "An agent useful in the treatment or prevention of coccidiosis in man or animals." []
is_a: CHEBI:35820 ! antiprotozoal drug

[Term]
id: CHEBI:35819
name: branched-chain fatty acid
def: "Any fatty acid in which the parent hydrocarbon chain has one or more alkyl substituents; a common component in animal and bacterial lipids. The fatty acyl chain is usually saturated and the substituent a methyl group; however, unsaturated BCFAs are found in marine animals, and branches other than methyl are found in microbial lipids." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:58955 ! is protonated form of branched-chain fatty acid anion

[Term]
id: CHEBI:35820
name: antiprotozoal drug
def: "Any antimicrobial drug which is used to treat or prevent protozoal infections." []
is_a: CHEBI:35442 ! antiparasitic agent
is_a: CHEBI:36043 ! antimicrobial drug

[Term]
id: CHEBI:35821
name: anticholesteremic drug
def: "A substance used to lower plasma cholesterol levels." []
is_a: CHEBI:35679 ! antilipemic drug

[Term]
id: CHEBI:35822
name: arsenic hydride
is_a: CHEBI:22632 ! arsenic molecular entity
is_a: CHEBI:35881 ! pnictogen hydride

[Term]
id: CHEBI:35823
name: arsanes
def: "The saturated hydrides of tervalent arsenic, having the general formula As<small><sub><em>n</em></sub></small>H<small><sub><em>n</em>+2</sub></small>." []
is_a: CHEBI:35822 ! arsenic hydride

[Term]
id: CHEBI:35826
name: elemental arsenic
is_a: CHEBI:22632 ! arsenic molecular entity
is_a: CHEBI:33465 ! elemental pnictogen

[Term]
id: CHEBI:35827
name: monoatomic arsenic
is_a: CHEBI:35826 ! elemental arsenic

[Term]
id: CHEBI:35828
name: arsenic(3+)
is_a: CHEBI:35827 ! monoatomic arsenic

[Term]
id: CHEBI:35841
name: uricosuric drug
def: "A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma." []
is_a: CHEBI:35845 ! gout suppressant
is_a: CHEBI:35846 ! renal agent

[Term]
id: CHEBI:35842
name: antirheumatic drug
def: "A drug used to treat rheumatoid arthritis." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35843
name: arsine oxides
def: "H<small><sub>3</sub></small>As=O and its hydrocarbyl derivatives." []
is_a: CHEBI:22632 ! arsenic molecular entity

[Term]
id: CHEBI:35845
name: gout suppressant
def: "A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout." []
is_a: CHEBI:35842 ! antirheumatic drug

[Term]
id: CHEBI:35846
name: renal agent
def: "A drug used for its effect on the kidneys' regulation of body fluid composition and volume." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:35850
name: sulfone
def: "An organosulfur compound having the structure RS(=O)<small><sub>2</sub></small>R (R ≠ H)." []
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:35856
name: lipoxygenase inhibitor
def: "A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes." []
is_a: CHEBI:76837 ! EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor

[Term]
id: CHEBI:35857
name: benzothiophene
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent
is_a: CHEBI:38767 ! benzothiophenes

[Term]
id: CHEBI:35858
name: 1-benzothiophene
is_a: CHEBI:35857 ! benzothiophene
is_a: CHEBI:38836 ! 1-benzothiophenes

[Term]
id: CHEBI:35868
name: hydroxy monocarboxylic acid
def: "Any monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent." []
is_a: CHEBI:24669 ! hydroxy carboxylic acid
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0018034 CHEBI:36059 ! is protonated form of hydroxy monocarboxylic acid anion

[Term]
id: CHEBI:35871
name: oxo monocarboxylic acid
def: "Any monocarboxylic acid having at least one additional oxo functional group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:25754 ! oxo carboxylic acid
relationship: RO:0018034 CHEBI:35902 ! is protonated form of oxo monocarboxylic acid anion

[Term]
id: CHEBI:35873
name: carboxylic anhydride
def: "Anhydrides derived from carboxylic acids." []
is_a: CHEBI:36586 ! carbonyl compound
is_a: CHEBI:36606 ! acid anhydride

[Term]
id: CHEBI:35875
name: imidazopyrimidine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:33833 ! heteroarene
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:35878
name: phosphanes
def: "The saturated hydrides of tervalent phosphorus having the general formula P<small><sub><em>n</em></sub></small>H<small><sub><em>n</em>+2</sub></small>." []
is_a: CHEBI:35879 ! phosphorus hydride

[Term]
id: CHEBI:35879
name: phosphorus hydride
is_a: CHEBI:26082 ! phosphorus molecular entity
is_a: CHEBI:35881 ! pnictogen hydride

[Term]
id: CHEBI:35881
name: pnictogen hydride
is_a: CHEBI:33242 ! inorganic hydride
is_a: CHEBI:33302 ! pnictogen molecular entity

[Term]
id: CHEBI:35883
name: phosphine
def: "Phosphane (PH<small><sub>3</sub></small>) and compounds derived from it by substituting one, two or three hydrogen atoms by hydrocarbyl groups: RPH<small><sub>2</sub></small>, R<small><sub>2</sub></small>PH, R<small><sub>3</sub></small>P (R ≠ H) are called primary, secondary and tertiary phosphines, respectively. A specific phosphine is preferably named as a substituted phosphane." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26082 ! phosphorus molecular entity
relationship: RO:0000087 CHEBI:35223 ! has role catalyst

[Term]
id: CHEBI:35902
name: oxo monocarboxylic acid anion
is_a: CHEBI:35757 ! monocarboxylic acid anion
is_a: CHEBI:35903 ! oxo carboxylic acid anion
relationship: RO:0018033 CHEBI:35871 ! is deprotonated form of oxo monocarboxylic acid

[Term]
id: CHEBI:35903
name: oxo carboxylic acid anion
def: "Any carboxylic acid anion containing at least one oxo group." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:25754 ! is deprotonated form of oxo carboxylic acid

[Term]
id: CHEBI:35907
name: glutarate(1-)
def: "A dicarboxylic acid monoanion that is the conjugate base of glutaric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24329 ! glutarate
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:30921 ! is protonated form of glutarate(2-)

[Term]
id: CHEBI:35910
name: 2-oxo monocarboxylic acid
def: "Any monocarboxylic acid having a 2-oxo substituent." []
is_a: CHEBI:35871 ! oxo monocarboxylic acid
relationship: RO:0018034 CHEBI:35179 ! is protonated form of 2-oxo monocarboxylic acid anion

[Term]
id: CHEBI:35915
name: sterol ester
def: "A steroid ester obtained by formal condensation of the carboxy group of any carboxylic acid with the 3-hydroxy group of a sterol." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:47880 ! steroid ester

[Term]
id: CHEBI:35923
name: hydroperoxide
def: "A monosubstitution product of hydrogen peroxide, HOOH." []
is_a: CHEBI:24651 ! hydroxides
relationship: BFO:0000051 CHEBI:29792 ! has part hydroperoxy group

[Term]
id: CHEBI:35924
name: peroxol
def: "Monosubstitution products of hydrogen peroxide HOOH, having the skeleton ROOH, in which R is any organyl group." []
is_a: CHEBI:35923 ! hydroperoxide
is_a: CHEBI:36963 ! organooxygen compound
is_a: CHEBI:37863 ! chalcoperoxol

[Term]
id: CHEBI:35931
name: delta-amino acid
def: "A non-proteinogenic amino acid in which the amino group is located on the carbon atom at the position δ to the carboxy group." []
is_a: CHEBI:83820 ! non-proteinogenic amino acid

[Term]
id: CHEBI:35932
name: 3-methyl-2-oxovaleric acid
def: "A 2-oxo monocarboxylic acid that is valeric acid carrying oxo- and methyl substituents at C-2 and C-3, respectively. An α-keto acid analogue and metabolite of isoleucine in man, animals and bacteria. Used as a clinical marker for maple syrup urine disease (MSUD)." []
is_a: CHEBI:191197 ! branched-chain keto acid
is_a: CHEBI:35910 ! 2-oxo monocarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:28654 ! is protonated form of 3-methyl-2-oxovalerate
relationship: RO:0018038 CHEBI:17418 ! has functional parent valeric acid

[Term]
id: CHEBI:35941
name: serotonergic agonist
def: "An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders." []
is_a: CHEBI:48278 ! serotonergic drug

[Term]
id: CHEBI:35942
name: neurotransmitter agent
def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:35950
name: 4-oxo monocarboxylic acid
is_a: CHEBI:35871 ! oxo monocarboxylic acid
relationship: RO:0018034 CHEBI:35974 ! is protonated form of 4-oxo monocarboxylic acid anion

[Term]
id: CHEBI:35952
name: 5-oxo monocarboxylic acid
is_a: CHEBI:35871 ! oxo monocarboxylic acid
relationship: RO:0018033 CHEBI:35975 ! is deprotonated form of 5-oxo monocarboxylic acid anion

[Term]
id: CHEBI:35969
name: 3-hydroxy monocarboxylic acid
def: "A hydroxy monocarboxylic acid that has a hydroxy group β to the carboxy group." []
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid
is_a: CHEBI:61355 ! 3-hydroxy carboxylic acid

[Term]
id: CHEBI:35972
name: dihydroxy monocarboxylic acid
def: "Any  hydroxy monocarboxylic acid carrying at least two hydroxy groups." []
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid

[Term]
id: CHEBI:35973
name: 3-oxo monocarboxylic acid anion
def: "An oxo monocarboxylic acid anion having the oxo group located at the 3-position (R = H or organyl group)." []
is_a: CHEBI:35902 ! oxo monocarboxylic acid anion
relationship: RO:0018033 CHEBI:47881 ! is deprotonated form of 3-oxo monocarboxylic acid

[Term]
id: CHEBI:35974
name: 4-oxo monocarboxylic acid anion
is_a: CHEBI:35902 ! oxo monocarboxylic acid anion
relationship: RO:0018033 CHEBI:35950 ! is deprotonated form of 4-oxo monocarboxylic acid

[Term]
id: CHEBI:35975
name: 5-oxo monocarboxylic acid anion
is_a: CHEBI:35902 ! oxo monocarboxylic acid anion
relationship: RO:0018034 CHEBI:35952 ! is protonated form of 5-oxo monocarboxylic acid

[Term]
id: CHEBI:35983
name: 7-oxo monocarboxylic acid
is_a: CHEBI:35871 ! oxo monocarboxylic acid

[Term]
id: CHEBI:35987
name: diamino acid
def: "Any amino acid carrying two amino groups." []
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018034 CHEBI:59561 ! is protonated form of diamino acid anion

[Term]
id: CHEBI:35990
name: bridged compound
def: "A polycyclic compound that contains more than one ring with at least two common atoms (also known as bridgehead carbons) that are not adjacent to each other." []
is_a: CHEBI:33635 ! polycyclic compound

[Term]
id: CHEBI:35992
name: penams
def: "Natural and synthetic antibiotics containing the 4-thia-1-azabicyclo[3.2.0]heptan-7-one structure, generally assumed to have the 5<i>R</i> configuration unless otherwise specified." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:27933 ! beta-lactam antibiotic
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:36005
name: docosahexaenoic acid
def: "Any C<small><sub>22</sub></small> polyunsaturated fatty acid containing six double bonds." []
is_a: CHEBI:132544 ! fatty acid 22:6
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:53339 ! olefinic fatty acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:78060 ! is protonated form of docosahexaenoate

[Term]
id: CHEBI:36006
name: icosapentaenoic acid
def: "Any straight-chain, C<small><sub>20</sub></small> polyunsaturated fatty acid having five C=C double bonds." []
is_a: CHEBI:132540 ! fatty acid 20:5
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:53339 ! olefinic fatty acid
is_a: CHEBI:59202 ! straight-chain fatty acid

[Term]
id: CHEBI:36009
name: omega-6 fatty acid
def: "A family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the n-6 position, i.e., the sixth bond from the methyl end of the fatty acid." []
is_a: CHEBI:59549 ! essential fatty acid

[Term]
id: CHEBI:36014
name: chloromethane
def: "A one-carbon compound that is methane in which one of the hydrogens is replaced by a chloro group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23148 ! chloromethanes
is_a: CHEBI:25253 ! methyl halides
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:36015
name: 1,1,1-trichloroethane
def: "A member of the class of chloroethanes carrying three chloro substituents at position 1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36016 ! chloroethanes
relationship: RO:0000087 CHEBI:48354 ! has role polar solvent

[Term]
id: CHEBI:36016
name: chloroethanes
def: "A chloroalkane that is ethane in which one or more of the  hydrogens is replaced by chlorine." []
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:23128 ! chloroalkane
relationship: RO:0018040 CHEBI:42266 ! has parent hydride ethane

[Term]
id: CHEBI:36018
name: 1,1,2-trichloroethane
def: "A member of the class of chloroethanes that is ethane substituted by chloro groups at positions 1, 1 and 2." []
is_a: CHEBI:36016 ! chloroethanes

[Term]
id: CHEBI:36021
name: octadec-9-enoic acid
def: "An octadecenoic acid with a double bond at C-9." []
is_a: CHEBI:25634 ! octadecenoic acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:132944 ! is protonated form of octadec-9-enoate
relationship: RO:0018040 CHEBI:37605 ! has parent hydride octadec-9-ene

[Term]
id: CHEBI:36026
name: 1,1,2,2-tetrachloroethane
def: "A member of the class of  chloroethanes that is ethane substituted by chloro groups at positions 1, 1, 2 and 2." []
is_a: CHEBI:36016 ! chloroethanes

[Term]
id: CHEBI:36027
name: stilbenol
def: "Any  stilbenoid with at least one phenolic group." []
is_a: CHEBI:26776 ! stilbenoid
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:36029
name: butenoate
is_a: CHEBI:2580 ! unsaturated fatty acid anion
is_a: CHEBI:58951 ! short-chain fatty acid anion

[Term]
id: CHEBI:36033
name: icosatetraenoic acid
def: "A 20-carbon, polyunsaturated fatty acid having four double bonds at unspecified positions." []
is_a: CHEBI:132539 ! fatty acid 20:4
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:53339 ! olefinic fatty acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78804 ! has role Caenorhabditis elegans metabolite
relationship: RO:0018034 CHEBI:62920 ! is protonated form of icosatetraenoate

[Term]
id: CHEBI:36043
name: antimicrobial drug
def: "A drug used to treat or prevent microbial infections." []
is_a: CHEBI:33281 ! antimicrobial agent
is_a: CHEBI:35441 ! antiinfective agent

[Term]
id: CHEBI:36044
name: antiviral drug
def: "A substance used in the prophylaxis or therapy of virus diseases." []
is_a: CHEBI:22587 ! antiviral agent
is_a: CHEBI:36043 ! antimicrobial drug

[Term]
id: CHEBI:36047
name: antibacterial drug
def: "A drug used to treat or prevent bacterial infections." []
is_a: CHEBI:33282 ! antibacterial agent
is_a: CHEBI:36043 ! antimicrobial drug

[Term]
id: CHEBI:36053
name: acaricide drug
def: "A drug used to treat infestations with arthropods of the subclass <em>Acari</em> (mites and ticks)." []
is_a: CHEBI:22153 ! acaricide
is_a: CHEBI:35442 ! antiparasitic agent

[Term]
id: CHEBI:36054
name: benzoate ester
def: "Esters of benzoic acid or substituted benzoic acids." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:62732 ! aromatic ester
relationship: RO:0018038 CHEBI:22723 ! has functional parent benzoic acids

[Term]
id: CHEBI:36055
name: furoic acid
def: "A monocarboxylic acid that consists of a furan ring having a single carboxylic acid group on any ring position and derivatives thereof." []
is_a: CHEBI:24129 ! furans
is_a: CHEBI:25384 ! monocarboxylic acid

[Term]
id: CHEBI:36056
name: furancarboxylate
is_a: CHEBI:35757 ! monocarboxylic acid anion

[Term]
id: CHEBI:36059
name: hydroxy monocarboxylic acid anion
def: "Any monocarboxylic acid anion carrying at least one hydroxy substituent." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:35868 ! is deprotonated form of hydroxy monocarboxylic acid

[Term]
id: CHEBI:36063
name: oxytocic
def: "A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients)." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:36064
name: taxane
is_a: CHEBI:35190 ! diterpene
is_a: CHEBI:35662 ! terpenoid fundamental parent

[Term]
id: CHEBI:36078
name: cholanoid
is_a: CHEBI:35341 ! steroid
relationship: RO:0018040 CHEBI:35519 ! has parent hydride cholane

[Term]
id: CHEBI:36080
name: protein
def: "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." []
is_a: CHEBI:33695 ! information biomacromolecule
relationship: BFO:0000051 CHEBI:16541 ! has part protein polypeptide chain

[Term]
id: CHEBI:36084
name: dihydroxybenzoate
def: "A hydroxybenzoate that is the  conjugate base of dihydroxybenzoic acid." []
is_a: CHEBI:24675 ! hydroxybenzoate
relationship: RO:0018033 CHEBI:23778 ! is deprotonated form of dihydroxybenzoic acid

[Term]
id: CHEBI:36085
name: trihydroxybenzoate
is_a: CHEBI:24675 ! hydroxybenzoate

[Term]
id: CHEBI:36087
name: cinnamate ester
is_a: CHEBI:26004 ! phenylpropanoid
is_a: CHEBI:51702 ! enoate ester
relationship: RO:0018038 CHEBI:23252 ! has functional parent cinnamic acids

[Term]
id: CHEBI:36093
name: inorganic chloride
is_a: CHEBI:23114 ! chloride salt
is_a: CHEBI:24839 ! inorganic salt

[Term]
id: CHEBI:36094
name: organic chloride salt
is_a: CHEBI:23114 ! chloride salt
is_a: CHEBI:51069 ! organic halide salt

[Term]
id: CHEBI:36114
name: chromenylium
def: "A member of the class of chromenyliums that is chromene with a protonated oxygen." []
is_a: CHEBI:72704 ! chromenyliums

[Term]
id: CHEBI:36121
name: flavylium
def: "A member of the class of chromenyliums that is chromenylium with a phenyl substituent at position 2." []
is_a: CHEBI:72704 ! chromenyliums
relationship: RO:0018038 CHEBI:36114 ! has functional parent chromenylium

[Term]
id: CHEBI:36123
name: cyclitol carboxylic acid
is_a: CHEBI:33598 ! carbocyclic compound
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid

[Term]
id: CHEBI:36124
name: (+)-quinic acid
def: "The (+)-enantiomer of quinic acid." []
is_a: CHEBI:26493 ! quinic acid
relationship: RO:0018039 CHEBI:17521 ! is enantiomer of (-)-quinic acid

[Term]
id: CHEBI:36125
name: cyclitol carboxylic acid anion
is_a: CHEBI:35757 ! monocarboxylic acid anion

[Term]
id: CHEBI:36126
name: cyclohexenecarboxylate
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:23483 ! is deprotonated form of cyclohexenecarboxylic acid

[Term]
id: CHEBI:36128
name: cyclopropanecarboxylate
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:23500 ! is deprotonated form of cyclopropanecarboxylic acid

[Term]
id: CHEBI:36130
name: cyclic terpene ketone
def: "An alicyclic ketone in which the carbocyclic ring structure forms part of a terpene skeleton." []
is_a: CHEBI:26872 ! terpene ketone
is_a: CHEBI:36132 ! alicyclic ketone

[Term]
id: CHEBI:36132
name: alicyclic ketone
def: "A cyclic ketone in which the carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system." []
is_a: CHEBI:3992 ! cyclic ketone
relationship: RO:0018040 CHEBI:33654 ! has parent hydride alicyclic compound

[Term]
id: CHEBI:36140
name: cyclopentanones
def: "Any alicyclic ketone that consists of a cyclopentane skeleton substituted by at least one oxo group." []
is_a: CHEBI:36132 ! alicyclic ketone

[Term]
id: CHEBI:36141
name: quinone
def: "Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of ‒CH= groups into ‒C(=O)‒ groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included)." []
is_a: CHEBI:3992 ! cyclic ketone

[Term]
id: CHEBI:36149
name: 2-hydroxyglutarate(1-)
def: "A dicarboxylic acid monoanion resulting from the removal of a proton from one of the carboxylic acid groups of 2-hydroxyglutaric acid." []
is_a: CHEBI:132941 ! 2-hydroxyglutarate
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018034 CHEBI:11596 ! is protonated form of 2-hydroxyglutarate(2-)
relationship: RO:0018038 CHEBI:35907 ! has functional parent glutarate(1-)

[Term]
id: CHEBI:36151
name: heptenoic acid
def: "A C<small><sub>7</sub></small>, medium-chain fatty acid carrying a double bond at any position along the main chain." []
is_a: CHEBI:25413 ! monounsaturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid

[Term]
id: CHEBI:36180
name: butenedioate
is_a: CHEBI:61336 ! C4-dicarboxylate
relationship: RO:0018033 CHEBI:37155 ! is deprotonated form of hydrogen butenedioate

[Term]
id: CHEBI:36186
name: cyclobutanedicarboxylic acid
is_a: CHEBI:156473 ! cyclobutanes
is_a: CHEBI:35692 ! dicarboxylic acid

[Term]
id: CHEBI:36205
name: cyclobutanedicarboxylate
is_a: CHEBI:156473 ! cyclobutanes
is_a: CHEBI:28965 ! dicarboxylic acid dianion

[Term]
id: CHEBI:36219
name: alpha-lactose
def: "The α-anomer of lactose." []
is_a: CHEBI:17716 ! lactose

[Term]
id: CHEBI:36233
name: disaccharide
def: "A compound in which two monosaccharides are joined by a glycosidic bond." []
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:36234
name: chenodeoxycholate
def: "Conjugate base of chenodeoxycholic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131878 ! cholanic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16755 ! is deprotonated form of chenodeoxycholic acid

[Term]
id: CHEBI:36235
name: bile acid anion
is_a: CHEBI:35757 ! monocarboxylic acid anion
is_a: CHEBI:50160 ! steroid acid anion

[Term]
id: CHEBI:36237
name: cholanic acid
def: "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." []
is_a: CHEBI:36278 ! cholanic acids

[Term]
id: CHEBI:36238
name: 5beta-cholanic acid
is_a: CHEBI:36237 ! cholanic acid
is_a: CHEBI:36248 ! 5beta-cholanic acids

[Term]
id: CHEBI:36243
name: propanoate ester
def: "Any carboxylic ester where the carboxylic acid component is  propionic acid." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:36244
name: dicarboxylic acid monoester
def: "A monoester of a dicarboxylic acid." []
is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:33575 ! carboxylic acid
relationship: RO:0018034 CHEBI:131605 ! is protonated form of dicarboxylic acid monoester(1-)

[Term]
id: CHEBI:36248
name: 5beta-cholanic acids
def: "Members of the class of cholanic acids based on a 5β-cholane skeleton." []
is_a: CHEBI:136889 ! 5beta steroid
is_a: CHEBI:36278 ! cholanic acids
relationship: RO:0018040 CHEBI:20664 ! has parent hydride 5beta-cholane

[Term]
id: CHEBI:36249
name: bile acid conjugate
def: "Any bile acid conjugated to a functional group that gives additional hydrophilicity or charge to the molecule. Molecules used for conjugation are: glycine, taurine (and other amino acids); sulfuric acid (for which the term ''sulfate'' may be used); glucuronic acid (for which the term ''glucuronate'' may be used); glucose and other uncharged sugars; and coenzyme A." []
is_a: CHEBI:36078 ! cholanoid

[Term]
id: CHEBI:36257
name: taurocholate
def: "An organosulfonate oxoanion that is the conjugate base of taurocholic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131879 ! cholanic acid conjugate anion
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28865 ! is deprotonated form of taurocholic acid

[Term]
id: CHEBI:36258
name: but-2-enoate
def: "The conjugate base of but-2-enoic acid." []
is_a: CHEBI:36029 ! butenoate
relationship: RO:0018033 CHEBI:17217 ! is deprotonated form of 2-butenoic acid

[Term]
id: CHEBI:36265
name: transition element oxoacid
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:36277
name: bile acid salt
def: "A salt of a bile acid." []
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:36078 ! cholanoid

[Term]
id: CHEBI:36278
name: cholanic acids
is_a: CHEBI:36078 ! cholanoid
is_a: CHEBI:47891 ! steroid acid

[Term]
id: CHEBI:36281
name: caffeic acid
def: "A hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in <i>cis</i> and <i>trans</i> forms; the latter is the more common." []
is_a: CHEBI:24689 ! hydroxycinnamic acid
is_a: CHEBI:33566 ! catechols
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:64964 ! has role EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
relationship: RO:0000087 CHEBI:64996 ! has role EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
relationship: RO:0000087 CHEBI:76797 ! has role EC 2.5.1.18 (glutathione transferase) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:36299
name: tricarboxylic acid monoanion
is_a: CHEBI:35753 ! tricarboxylic acid anion

[Term]
id: CHEBI:36300
name: tricarboxylic acid dianion
is_a: CHEBI:35753 ! tricarboxylic acid anion

[Term]
id: CHEBI:36306
name: icosa-5,8,11,14-tetraenoic acid
def: "Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14." []
is_a: CHEBI:36033 ! icosatetraenoic acid

[Term]
id: CHEBI:36309
name: cyclic tetrapyrrole
is_a: CHEBI:26932 ! tetrapyrrole
is_a: CHEBI:47882 ! cyclic polypyrrole

[Term]
id: CHEBI:36313
name: glycerophosphocholine
def: "The glycerol phosphate ester of a phosphocholine. A nutrient with many different roles in human health." []
is_a: CHEBI:36700 ! phosphocholines
is_a: CHEBI:37739 ! glycerophospholipid

[Term]
id: CHEBI:363227
name: 6alpha,20xi-murideoxycholic acid
def: "The 6α,20ξ-stereoisomer of murideoxycholic acid." []
is_a: CHEBI:36835 ! 3alpha-hydroxy steroid
is_a: CHEBI:36850 ! 6alpha-hydroxy steroid

[Term]
id: CHEBI:36326
name: octadecanoid
def: "Unsaturated C<small><sub>18</sub></small> fatty acids and skeletally related compounds." []
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:27208 ! unsaturated fatty acid
relationship: RO:0018034 CHEBI:131860 ! is protonated form of octadecanoid anion

[Term]
id: CHEBI:36329
name: HPODE
def: "Hydroperoxy-octadecadienoic acids, formed in mammalian cells by peroxidation of linoleic acid." []
is_a: CHEBI:189832 ! hydroperoxy polyunsaturated fatty acid
is_a: CHEBI:36326 ! octadecanoid
relationship: RO:0018034 CHEBI:131862 ! is protonated form of HPODE(1-)
relationship: RO:0018038 CHEBI:17351 ! has functional parent linoleic acid

[Term]
id: CHEBI:36333
name: local anaesthetic
def: "Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block." []
is_a: CHEBI:38867 ! anaesthetic

[Term]
id: CHEBI:36334
name: naphthalene-1,3,5-trisulfonic acid
is_a: CHEBI:36336 ! naphthalenesulfonic acid

[Term]
id: CHEBI:36335
name: trypanocidal drug
def: "A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida." []
is_a: CHEBI:35820 ! antiprotozoal drug

[Term]
id: CHEBI:36336
name: naphthalenesulfonic acid
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:33555 ! arenesulfonic acid

[Term]
id: CHEBI:36337
name: strychnidine
is_a: CHEBI:26509 ! quinoline alkaloid
is_a: CHEBI:38482 ! indole alkaloid fundamental parent
is_a: CHEBI:38514 ! quinoline alkaloid fundamental parent
is_a: CHEBI:52157 ! organic heteroheptacyclic compound
is_a: CHEBI:65323 ! monoterpenoid indole alkaloid

[Term]
id: CHEBI:36338
name: lepton
def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek λεπτοσ (small, thin)." []
is_a: CHEBI:33233 ! fundamental particle
is_a: CHEBI:36340 ! fermion

[Term]
id: CHEBI:36339
name: baryon
def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek βαρυσ (heavy)." []
is_a: CHEBI:36340 ! fermion
is_a: CHEBI:36344 ! hadron

[Term]
id: CHEBI:36340
name: fermion
def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." []
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36341
name: boson
def: "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." []
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36342
name: subatomic particle
def: "A particle smaller than an atom." []

[Term]
id: CHEBI:36343
name: composite particle
def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." []
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36344
name: hadron
def: "Hadron is a subatomic particle which experiences the strong force." []
is_a: CHEBI:36343 ! composite particle

[Term]
id: CHEBI:36347
name: nuclear particle
def: "A nucleus or any of its constituents in any of their energy states." []
is_a: CHEBI:36342 ! subatomic particle

[Term]
id: CHEBI:36357
name: polyatomic entity
def: "Any molecular entity consisting of more than one atom." []
is_a: CHEBI:23367 ! molecular entity
relationship: BFO:0000051 CHEBI:24433 ! has part group

[Term]
id: CHEBI:36358
name: polyatomic ion
def: "An ion consisting of more than one atom." []
is_a: CHEBI:24870 ! ion
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:36359
name: phosphorus oxoacid derivative
is_a: CHEBI:33241 ! oxoacid derivative
is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives
relationship: RO:0018038 CHEBI:33457 ! has functional parent phosphorus oxoacid

[Term]
id: CHEBI:36360
name: phosphorus oxoacids and derivatives
is_a: CHEBI:26082 ! phosphorus molecular entity

[Term]
id: CHEBI:36361
name: phosphorous acid
is_a: CHEBI:33457 ! phosphorus oxoacid
relationship: RO:0018034 CHEBI:29258 ! is protonated form of dihydrogenphosphite
relationship: RO:0018036 CHEBI:44976 ! is tautomer of phosphonic acid

[Term]
id: CHEBI:36364
name: alkaline earth salt
is_a: CHEBI:24866 ! salt
is_a: CHEBI:33299 ! alkaline earth molecular entity

[Term]
id: CHEBI:3638
name: chloroquine
def: "An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:36709 ! aminoquinoline
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:88230 ! has role autophagy inhibitor
relationship: RO:0018033 CHEBI:149484 ! is deprotonated form of chloroquine(2+)

[Term]
id: CHEBI:36386
name: dichloroacetic acid
def: "An organochlorine compound comprising acetic acid carrying two chloro substituents at the 2-position. It occurs in nature in seaweed, <em>Asparagopsis taxiformis</em>." []
synonym: "Dichloroacetate" EXACT [KEGG_COMPOUND]
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:74783 ! has role astringent
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0018034 CHEBI:28240 ! is protonated form of dichloroacetate
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:36387
name: chloroalkene
def: "A compound derived from an alkene by replacing a hydrogen atom with a chlorine atom." []
is_a: CHEBI:39482 ! chloroolefin
is_a: CHEBI:5610 ! haloalkene

[Term]
id: CHEBI:36388
name: saturated organic heterocyclic parent
is_a: CHEBI:35552 ! heterocyclic organic fundamental parent

[Term]
id: CHEBI:36389
name: saturated organic heteromonocyclic parent
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:36388 ! saturated organic heterocyclic parent

[Term]
id: CHEBI:3639
name: chlorothalonil
def: "A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops." []
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:51308 ! dinitrile
is_a: CHEBI:87034 ! aromatic fungicide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:38218 ! has functional parent isophthalonitrile

[Term]
id: CHEBI:36401
name: cycloalkadiene
def: "An unsaturated monocyclic hydrocarbon having two endocyclic double bonds." []
is_a: CHEBI:36403 ! monocyclic olefin

[Term]
id: CHEBI:36403
name: monocyclic olefin
def: "A monocyclic hydrocarbon having any number of double bonds." []
is_a: CHEBI:33642 ! cyclic olefin

[Term]
id: CHEBI:36404
name: cyclohexene
def: "A cycloalkene that is cylohexane with a single double bond." []
is_a: CHEBI:33643 ! cycloalkene

[Term]
id: CHEBI:36413
name: anabolic agent
def: "A compound which stimulates anabolism and inhibits catabolism. Anabolic agents stimulate the development of muscle mass, strength, and power." []
is_a: CHEBI:24621 ! hormone

[Term]
id: CHEBI:36416
name: mancude organic heterotricyclic parent
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:35571 ! mancude organic heterocyclic parent

[Term]
id: CHEBI:36434
name: octadecatrienoate
def: "A C<small><sub>18</sub></small>, straight-chain, unsaturated long-chain fatty acid anion and the conjugate base of its corresponding octadecatrienoic acid, formed by deprotonation of the carboxylic acid group." []
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:59203 ! straight-chain fatty acid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:25633 ! is deprotonated form of octadecatrienoic acid

[Term]
id: CHEBI:36464
name: (R)-mevalonate
def: "The (<i>R</i>)-enantiomer of mevalonate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:194520 ! 3,5-dihydroxy-3-methylpentanoate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17710 ! is deprotonated form of (R)-mevalonic acid
relationship: RO:0018039 CHEBI:18790 ! is enantiomer of (S)-mevalonate

[Term]
id: CHEBI:36468
name: polycyclic ether
is_a: CHEBI:37407 ! cyclic ether
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:3647
name: chlorpromazine
def: "A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an <em>N</em>,<em>N</em>-dimethylpropanamine moiety." []
is_a: CHEBI:32876 ! tertiary amine
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38093 ! phenothiazines
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37930 ! has role phenothiazine antipsychotic drug
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor

[Term]
id: CHEBI:36480
name: bisabolane
def: "A cycloalkane that is cyclohexane substituted by a methyl group at position 1 and by a 6-methylheptan-2-yl at position 4. Its skeleton structure is found in many sesquiterpenes and sesquiterpenoids." []
is_a: CHEBI:23453 ! cycloalkane
is_a: CHEBI:35189 ! sesquiterpene
is_a: CHEBI:35662 ! terpenoid fundamental parent

[Term]
id: CHEBI:36481
name: oleanane
is_a: CHEBI:35191 ! triterpene
is_a: CHEBI:35662 ! terpenoid fundamental parent

[Term]
id: CHEBI:36488
name: dammarane
is_a: CHEBI:35191 ! triterpene
is_a: CHEBI:35341 ! steroid
is_a: CHEBI:35662 ! terpenoid fundamental parent

[Term]
id: CHEBI:3649
name: chlorpromazine hydrochloride
def: "The hydrochloride salt of chlorpromazine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
is_a: CHEBI:38093 ! phenothiazines
relationship: BFO:0000051 CHEBI:3647 ! has part chlorpromazine
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:37930 ! has role phenothiazine antipsychotic drug

[Term]
id: CHEBI:36498
name: galactosylceramide
def: "Any of the cerebrosides in which the monosaccharide head group is galactose." []
is_a: CHEBI:23079 ! cerebroside
is_a: CHEBI:5254 ! galactolipid
is_a: CHEBI:62941 ! glycosylceramide

[Term]
id: CHEBI:36505
name: labdane
is_a: CHEBI:35190 ! diterpene
is_a: CHEBI:35662 ! terpenoid fundamental parent

[Term]
id: CHEBI:3654
name: chlorthalidone
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24897 ! isoindoles
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent

[Term]
id: CHEBI:36560
name: zinc oxide
is_a: CHEBI:27364 ! zinc molecular entity

[Term]
id: CHEBI:36562
name: main-group coordination entity
def: "A coordination entity in which the central atom to which the ligands are attached comes from groups 1, 2, 13, 14, 15, 16, 17, or 18 of the periodic table." []
is_a: CHEBI:33240 ! coordination entity
is_a: CHEBI:33579 ! main group molecular entity

[Term]
id: CHEBI:36563
name: zinc group coordination entity
is_a: CHEBI:33240 ! coordination entity
is_a: CHEBI:33673 ! zinc group molecular entity

[Term]
id: CHEBI:36565
name: cadmium coordination entity
is_a: CHEBI:22978 ! cadmium molecular entity
is_a: CHEBI:36563 ! zinc group coordination entity

[Term]
id: CHEBI:36566
name: zinc coordination entity
is_a: CHEBI:27364 ! zinc molecular entity
is_a: CHEBI:36563 ! zinc group coordination entity

[Term]
id: CHEBI:36586
name: carbonyl compound
def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." []
is_a: CHEBI:36587 ! organic oxo compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: BFO:0000051 CHEBI:23019 ! has part carbonyl group

[Term]
id: CHEBI:36587
name: organic oxo compound
def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." []
is_a: CHEBI:72695 ! organic molecule
relationship: BFO:0000051 CHEBI:46629 ! has part oxo group

[Term]
id: CHEBI:36604
name: metal carbonyl
def: "A coordination entity that is coordination complex of a metals with one or more carbon monoxide ligands." []
is_a: CHEBI:33240 ! coordination entity

[Term]
id: CHEBI:36605
name: phthalic anhydride
def: "The cyclic dicarboxylic anhydride that is the anhydride of phthalic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36609 ! cyclic dicarboxylic anhydride
is_a: CHEBI:38831 ! 2-benzofurans
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:36606
name: acid anhydride
def: "Compounds consisting of two acyl groups bonded to the same oxygen atom acyl‒O‒acyl." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:36607
name: cyclic acid anhydride
def: "Acid anhydrides derived by loss of water between two oxoacid functions R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> ≠ 0) (carboxylic, sulfonic, etc.) in the same molecule so as to close a ring." []
is_a: CHEBI:36606 ! acid anhydride

[Term]
id: CHEBI:36608
name: acyclic acid anhydride
is_a: CHEBI:36606 ! acid anhydride

[Term]
id: CHEBI:36609
name: cyclic dicarboxylic anhydride
def: "An acid anhydride derived by loss of water between two carboxylic groups in the same molecule so as to close a ring." []
is_a: CHEBI:35873 ! carboxylic anhydride
is_a: CHEBI:36607 ! cyclic acid anhydride

[Term]
id: CHEBI:36610
name: acetic anhydride
def: "An acyclic carboxylic anhydride derived from acetic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36631 ! acyclic carboxylic anhydride
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:33893 ! has role reagent

[Term]
id: CHEBI:36615
name: triterpenoid
def: "Any terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." []
is_a: CHEBI:26873 ! terpenoid
relationship: RO:0018040 CHEBI:35191 ! has parent hydride triterpene

[Term]
id: CHEBI:36616
name: quinoxaline
def: "A naphthyridine in which the nitrogens are at positions 1 and 4." []
is_a: CHEBI:36624 ! naphthyridine

[Term]
id: CHEBI:36622
name: benzimidazole
def: "A mancude organic heterobicyclic parent that is a heterocyclic organic compound comprising fused benzene and imidazole rings." []
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent

[Term]
id: CHEBI:36623
name: 4H-benzimidazole
is_a: CHEBI:36622 ! benzimidazole
relationship: RO:0018036 CHEBI:36639 ! is tautomer of 2H-benzimidazole
relationship: RO:0018036 CHEBI:36641 ! is tautomer of 3aH-benzimidazole
relationship: RO:0018036 CHEBI:41275 ! is tautomer of 1H-benzimidazole

[Term]
id: CHEBI:36624
name: naphthyridine
def: "Any one of eight organic heterobicyclic compounds that have a naphthalene skeleton in which two of the carbons are replaced by nitrogens. A 'closed' class." []
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent
is_a: CHEBI:50893 ! azaarene
is_a: CHEBI:52362 ! ortho-fused heteroarene

[Term]
id: CHEBI:36631
name: acyclic carboxylic anhydride
is_a: CHEBI:35873 ! carboxylic anhydride
is_a: CHEBI:36608 ! acyclic acid anhydride

[Term]
id: CHEBI:36639
name: 2H-benzimidazole
is_a: CHEBI:36622 ! benzimidazole
relationship: RO:0018036 CHEBI:36623 ! is tautomer of 4H-benzimidazole
relationship: RO:0018036 CHEBI:36641 ! is tautomer of 3aH-benzimidazole
relationship: RO:0018036 CHEBI:41275 ! is tautomer of 1H-benzimidazole

[Term]
id: CHEBI:36641
name: 3aH-benzimidazole
is_a: CHEBI:36622 ! benzimidazole
relationship: RO:0018036 CHEBI:36623 ! is tautomer of 4H-benzimidazole
relationship: RO:0018036 CHEBI:36639 ! is tautomer of 2H-benzimidazole
relationship: RO:0018036 CHEBI:41275 ! is tautomer of 1H-benzimidazole

[Term]
id: CHEBI:36651
name: tellurium coordination entity
is_a: CHEBI:33305 ! tellurium molecular entity
is_a: CHEBI:36562 ! main-group coordination entity

[Term]
id: CHEBI:36655
name: glyoxylate
def: "The conjugate base of glyoxylic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35179 ! 2-oxo monocarboxylic acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16891 ! is deprotonated form of glyoxylic acid

[Term]
id: CHEBI:36660
name: elemental tellurium
is_a: CHEBI:33305 ! tellurium molecular entity

[Term]
id: CHEBI:36668
name: aluminium coordination entity
is_a: CHEBI:33620 ! aluminium molecular entity
is_a: CHEBI:36562 ! main-group coordination entity

[Term]
id: CHEBI:36682
name: polychlorinated dibenzodioxine
def: "Any dibenzodioxine in which two or more hydrogens have been replaced by chlorines." []
is_a: CHEBI:134045 ! polychlorinated dibenzodioxines and related compounds
is_a: CHEBI:23825 ! dibenzodioxine
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:36683
name: organochlorine compound
def: "An organochlorine compound is a compound containing at least one carbon-chlorine bond." []
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:23117 ! chlorine molecular entity

[Term]
id: CHEBI:36685
name: chlorocarboxylic acid
def: "A carboxylic acid containing at least one chloro group." []
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:36686
name: chloroarene
def: "A compound derived from an arene by replacing a hydrogen atom with a chlorine atom." []
is_a: CHEBI:23115 ! chlorohydrocarbon
is_a: CHEBI:50887 ! haloarene

[Term]
id: CHEBI:36687
name: acyl chloride
def: "A compound consisting of an acyl group bonded to chlorine." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37579 ! acyl halide

[Term]
id: CHEBI:36688
name: heterotricyclic compound
is_a: CHEBI:33671 ! heteropolycyclic compound

[Term]
id: CHEBI:36693
name: 1,3-dichlorobenzene
def: "A dichlorobenzene carrying chloro substituents at positions 1 and 3." []
is_a: CHEBI:23697 ! dichlorobenzene

[Term]
id: CHEBI:36699
name: corticosteroid hormone
def: "Any of a class of steroid hormones that are produced in the adrenal cortex." []
is_a: CHEBI:26764 ! steroid hormone
is_a: CHEBI:50858 ! corticosteroid

[Term]
id: CHEBI:36700
name: phosphocholines
def: "Any compound having phosphocholine as part of its structure." []
is_a: CHEBI:23213 ! choline ester
is_a: CHEBI:23217 ! cholines
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:37734 ! phosphoric ester

[Term]
id: CHEBI:36702
name: 2-acyl-1-alkyl-sn-glycero-3-phosphocholine
def: "An alkyl,acyl-<em>sn</em>-glycero-3-phosphocholine in which unspecified alkyl and acyl groups are located at positions 1 and 2 respectively." []
is_a: CHEBI:35284 ! ammonium betaine
is_a: CHEBI:68489 ! alkyl,acyl-sn-glycero-3-phosphocholine
is_a: CHEBI:78186 ! 1-alkyl-2-acyl-glycero-3-phosphocholine

[Term]
id: CHEBI:36704
name: imiquimod
def: "An imidazoquinoline fused [4,5-<em>c</em>] carrying isobutyl and amino substituents at N-1 and C-4 respectively. A prescription medication, it acts as an immune response modifier and is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38776 ! imidazoquinoline
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36710 ! has role interferon inducer
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent

[Term]
id: CHEBI:36707
name: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine
def: "A 2-acyl-1-alkyl-<em>sn</em>-glycero-3-phosphocholine where the 2-<em>O</em>-acyl group is specified as acetyl; a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis." []
is_a: CHEBI:36702 ! 2-acyl-1-alkyl-sn-glycero-3-phosphocholine

[Term]
id: CHEBI:36709
name: aminoquinoline
def: "Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups." []
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:33860 ! aromatic amine

[Term]
id: CHEBI:36710
name: interferon inducer
def: "An agent that promotes the production and release of interferons." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:36718
name: dichlorobiphenyl
def: "Any polychlorobiphenyl with molecular formula C<small><sub>12</sub></small>H<small><sub>8</sub></small>Cl<small><sub>2</sub></small>." []
is_a: CHEBI:53156 ! polychlorobiphenyl

[Term]
id: CHEBI:36719
name: trichlorobiphenyl
def: "Any polychlorobiphenyl with molecular formula C<small><sub>12</sub></small>H<small><sub>7</sub></small>Cl<small><sub>3</sub></small>." []
is_a: CHEBI:53156 ! polychlorobiphenyl

[Term]
id: CHEBI:36720
name: tetrachlorobiphenyl
def: "Any polychlorobiphenyl with molecular formula C<small><sub>12</sub></small>H<small><sub>6</sub></small>Cl<small><sub>4</sub></small>." []
is_a: CHEBI:53156 ! polychlorobiphenyl

[Term]
id: CHEBI:36721
name: pentachlorobiphenyl
def: "Any polychlorobiphenyl with molecular formula C<small><sub>12</sub></small>H<small><sub>5</sub></small>Cl<small><sub>5</sub></small>." []
is_a: CHEBI:53156 ! polychlorobiphenyl

[Term]
id: CHEBI:36722
name: hexachlorobiphenyl
def: "Any polychlorobiphenyl with molecular formula C<small><sub>12</sub></small>H<small><sub>4</sub></small>Cl<small><sub>6</sub></small>." []
is_a: CHEBI:53156 ! polychlorobiphenyl

[Term]
id: CHEBI:36735
name: biladienes
def: "Compounds based on a biladiene skeleton." []
is_a: CHEBI:25046 ! linear tetrapyrrole

[Term]
id: CHEBI:36740
name: alpha-pinene
def: "A pinene that is bicyclo[3.1.1]hept-2-ene substituted by methyl groups at positions 2, 6 and 6 respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17187 ! pinene
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:36756
name: farnesane
def: "A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18310 ! alkane
is_a: CHEBI:35189 ! sesquiterpene
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:36757
name: farnesane sesquiterpenoid
is_a: CHEBI:26658 ! sesquiterpenoid
relationship: RO:0018040 CHEBI:36756 ! has parent hydride farnesane

[Term]
id: CHEBI:36758
name: apo carotenoid sesquiterpenoid
is_a: CHEBI:26658 ! sesquiterpenoid
is_a: CHEBI:53183 ! apo carotenoid

[Term]
id: CHEBI:36765
name: gibberellane
is_a: CHEBI:35190 ! diterpene
relationship: RO:0018039 CHEBI:36766 ! is enantiomer of ent-gibberellane

[Term]
id: CHEBI:36766
name: ent-gibberellane
is_a: CHEBI:35190 ! diterpene
relationship: RO:0018039 CHEBI:36765 ! is enantiomer of gibberellane

[Term]
id: CHEBI:36770
name: labdane diterpenoid
def: "Any diterpenoid with a labdane skeleton." []
is_a: CHEBI:23849 ! diterpenoid
relationship: RO:0018040 CHEBI:36505 ! has parent hydride labdane

[Term]
id: CHEBI:36773
name: camphor
def: "A cyclic monoterpene ketone that is bornane bearing an oxo substituent at position 2. A naturally occurring monoterpenoid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22912 ! bornane monoterpenoid
is_a: CHEBI:23446 ! cyclic monoterpene ketone
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:64952 ! has role anti-HSV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant

[Term]
id: CHEBI:36785
name: carbobicyclic compound
def: "A bicyclic compound in which all the ring atoms are carbon." []
is_a: CHEBI:33636 ! bicyclic compound
is_a: CHEBI:35294 ! carbopolycyclic compound

[Term]
id: CHEBI:36786
name: tetralins
def: "Compounds containing a tetralin skeleton." []
is_a: CHEBI:33836 ! benzenoid aromatic compound
is_a: CHEBI:36785 ! carbobicyclic compound

[Term]
id: CHEBI:36791
name: escitalopram
def: "A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has <i>S</i>-configuration at the chiral centre. It is the active enantiomer of citalopram." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:77397 ! 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0018033 CHEBI:77406 ! is deprotonated form of escitalopram(1+)
relationship: RO:0018039 CHEBI:36792 ! is enantiomer of (R)-citalopram

[Term]
id: CHEBI:36792
name: (R)-citalopram
def: "A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile that has <i>R</i>-configuration at the chiral centre. It is the inactive enantiomer of citalopram." []
is_a: CHEBI:77397 ! 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
relationship: RO:0018033 CHEBI:77405 ! is deprotonated form of (R)-citalopram(1+)
relationship: RO:0018039 CHEBI:36791 ! is enantiomer of escitalopram

[Term]
id: CHEBI:36793
name: (S)-bupropion
is_a: CHEBI:3219 ! bupropion
relationship: RO:0018039 CHEBI:36794 ! is enantiomer of (R)-bupropion

[Term]
id: CHEBI:36794
name: (R)-bupropion
is_a: CHEBI:3219 ! bupropion
relationship: RO:0018039 CHEBI:36793 ! is enantiomer of (S)-bupropion

[Term]
id: CHEBI:36796
name: duloxetine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26961 ! thiophenes
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor

[Term]
id: CHEBI:3680
name: chrysanthemic acid
def: "A monocarboxylic acid that is cyclopropanecarboxylic acid substituted by two methyl groups at position 2 and a 2-methylprop-1-en-1-yl group at position 3." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:51454 ! cyclopropanes
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018038 CHEBI:23500 ! has functional parent cyclopropanecarboxylic acid

[Term]
id: CHEBI:36807
name: hydrochloride
def: "A salt formally resulting from the reaction of hydrochloric acid with an organic base." []
is_a: CHEBI:36094 ! organic chloride salt

[Term]
id: CHEBI:36810
name: (trifluoromethyl)benzene
def: "A fluorohydrocarbon that is fluoroform in which the hydrogen is substituted by a phenyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:46695 ! fluorohydrocarbon
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:41550 ! has functional parent fluoroform

[Term]
id: CHEBI:36812
name: valerophenone
def: "An aromatic ketone that consists of benzene substituted by a pentanoyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component

[Term]
id: CHEBI:36814
name: 5-methoxyvalerophenone
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0018038 CHEBI:36812 ! has functional parent valerophenone

[Term]
id: CHEBI:36815
name: 5-methoxyvalerophenone O-(2-aminoethyl)oxime
is_a: CHEBI:36816 ! oxime O-ether
relationship: RO:0018038 CHEBI:36814 ! has functional parent 5-methoxyvalerophenone

[Term]
id: CHEBI:36816
name: oxime O-ether
def: "<em>O</em>-organyl oximes R<small><sub>2</sub></small>C=NOR' (R' ≠ H)." []
is_a: CHEBI:25698 ! ether
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:36819
name: seco-ergostane
is_a: CHEBI:35788 ! seco-steroid

[Term]
id: CHEBI:36820
name: ring assembly
def: "Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved." []
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:36823
name: pseudohalo group
is_a: CHEBI:24433 ! group

[Term]
id: CHEBI:36828
name: pseudohalide anion
is_a: CHEBI:36829 ! polyatomic monoanion

[Term]
id: CHEBI:36829
name: polyatomic monoanion
is_a: CHEBI:33273 ! polyatomic anion
is_a: CHEBI:36830 ! monoanion

[Term]
id: CHEBI:36830
name: monoanion
is_a: CHEBI:22563 ! anion

[Term]
id: CHEBI:36834
name: 3-hydroxy steroid
def: "Any hydroxy steroid carrying a hydroxy group at position 3." []
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36835
name: 3alpha-hydroxy steroid
def: "A 3-hydroxy steroid in which the 3-hydroxy substituent is in the α-position." []
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:36834 ! 3-hydroxy steroid

[Term]
id: CHEBI:36836
name: 3beta-hydroxy steroid
def: "A 3-hydroxy steroid in which the 3-hydroxy substituent is in the  β-position." []
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:36834 ! 3-hydroxy steroid

[Term]
id: CHEBI:36838
name: 17-hydroxy steroid
def: "A hydroxy steroid carrying a hydroxy group at position 17." []
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36840
name: 16-hydroxy steroid
def: "Any hydroxy steroid carrying a hydroxy group at position 16." []
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36841
name: 11-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36843
name: 7alpha-hydroxy steroid
def: "A 7-hydroxy steroid in which the hydroxy group at position 7 has an α-configuration." []
is_a: CHEBI:36844 ! 7-hydroxy steroid

[Term]
id: CHEBI:36844
name: 7-hydroxy steroid
def: "A hydroxy steroid carrying a hydroxy substituent at position 7." []
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36845
name: 12-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36846
name: 12alpha-hydroxy steroid
is_a: CHEBI:36845 ! 12-hydroxy steroid

[Term]
id: CHEBI:36847
name: 12beta-hydroxy steroid
is_a: CHEBI:36845 ! 12-hydroxy steroid

[Term]
id: CHEBI:36849
name: 6-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36850
name: 6alpha-hydroxy steroid
is_a: CHEBI:36849 ! 6-hydroxy steroid

[Term]
id: CHEBI:36853
name: hydroxy seco-steroid
is_a: CHEBI:35350 ! hydroxy steroid
is_a: CHEBI:35788 ! seco-steroid

[Term]
id: CHEBI:36856
name: hydrogen isocyanide
is_a: CHEBI:33405 ! hydracid
relationship: RO:0018034 CHEBI:17514 ! is protonated form of cyanide
relationship: RO:0018036 CHEBI:18407 ! is tautomer of hydrogen cyanide

[Term]
id: CHEBI:36857
name: 2-hydroxy steroid
def: "Any  hydroxy steroid carrying a hydroxy group at position 2." []
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36859
name: 2beta-hydroxy steroid
is_a: CHEBI:36857 ! 2-hydroxy steroid

[Term]
id: CHEBI:36860
name: 14-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36861
name: 14alpha-hydroxy steroid
is_a: CHEBI:36860 ! 14-hydroxy steroid

[Term]
id: CHEBI:36862
name: 14beta-hydroxy steroid
def: "A 14-hydroxy steroid in which the hydroxy group has a β-configuration." []
is_a: CHEBI:36860 ! 14-hydroxy steroid

[Term]
id: CHEBI:36863
name: 22-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36864
name: 25-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36865
name: 24-hydroxy steroid
is_a: CHEBI:35350 ! hydroxy steroid

[Term]
id: CHEBI:36867
name: pseudohalogen
def: "Compounds that resemble the halogen elements, X<small><sub>2</sub></small>, in their chemistry." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:36871
name: inorganic radical
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:26519 ! radical

[Term]
id: CHEBI:36873
name: radical anion
is_a: CHEBI:22563 ! anion
is_a: CHEBI:36875 ! radical ion

[Term]
id: CHEBI:36875
name: radical ion
def: "A radical that carries an electric charge." []
is_a: CHEBI:24870 ! ion
is_a: CHEBI:26519 ! radical

[Term]
id: CHEBI:36876
name: inorganic radical anion
is_a: CHEBI:36873 ! radical anion
is_a: CHEBI:36878 ! inorganic radical ion

[Term]
id: CHEBI:36878
name: inorganic radical ion
is_a: CHEBI:36871 ! inorganic radical
is_a: CHEBI:36875 ! radical ion

[Term]
id: CHEBI:36883
name: 6-oxo steroid
is_a: CHEBI:35789 ! oxo steroid

[Term]
id: CHEBI:36885
name: 20-oxo steroid
def: "An oxo steroid carrying an oxo group at position 20." []
is_a: CHEBI:35789 ! oxo steroid

[Term]
id: CHEBI:36887
name: 18-oxo steroid
is_a: CHEBI:35789 ! oxo steroid

[Term]
id: CHEBI:36892
name: elemental fluorine
is_a: CHEBI:33434 ! elemental halogen

[Term]
id: CHEBI:36893
name: elemental iodine
is_a: CHEBI:33434 ! elemental halogen

[Term]
id: CHEBI:36894
name: elemental bromine
is_a: CHEBI:33434 ! elemental halogen

[Term]
id: CHEBI:36895
name: monoatomic fluorine
is_a: CHEBI:36892 ! elemental fluorine

[Term]
id: CHEBI:36896
name: monoatomic bromine
is_a: CHEBI:36894 ! elemental bromine

[Term]
id: CHEBI:36897
name: monoatomic iodine
is_a: CHEBI:36893 ! elemental iodine

[Term]
id: CHEBI:36902
name: chalcogen hydride
is_a: CHEBI:33242 ! inorganic hydride
is_a: CHEBI:33304 ! chalcogen molecular entity

[Term]
id: CHEBI:36903
name: selenium hydride
is_a: CHEBI:26628 ! selenium molecular entity
is_a: CHEBI:36902 ! chalcogen hydride

[Term]
id: CHEBI:36904
name: elemental selenium
is_a: CHEBI:26628 ! selenium molecular entity

[Term]
id: CHEBI:36908
name: argon molecular entity
is_a: CHEBI:33583 ! noble gas molecular entity
relationship: BFO:0000051 CHEBI:49475 ! has part argon atom

[Term]
id: CHEBI:36911
name: radon molecular entity
is_a: CHEBI:33583 ! noble gas molecular entity
relationship: BFO:0000051 CHEBI:33314 ! has part radon atom

[Term]
id: CHEBI:36914
name: inorganic ion
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:24870 ! ion

[Term]
id: CHEBI:36915
name: inorganic cation
is_a: CHEBI:36914 ! inorganic ion
is_a: CHEBI:36916 ! cation

[Term]
id: CHEBI:36916
name: cation
def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." []
synonym: "Cation" EXACT [KEGG_COMPOUND]
is_a: CHEBI:24870 ! ion

[Term]
id: CHEBI:36918
name: antimony hydride
is_a: CHEBI:35881 ! pnictogen hydride
is_a: CHEBI:36919 ! antimony molecular entity

[Term]
id: CHEBI:36919
name: antimony molecular entity
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: BFO:0000051 CHEBI:30513 ! has part antimony atom

[Term]
id: CHEBI:36922
name: elemental antimony
is_a: CHEBI:36919 ! antimony molecular entity

[Term]
id: CHEBI:36943
name: aryl phosphate
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:37734 ! phosphoric ester

[Term]
id: CHEBI:36946
name: thiourea
def: "The simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur." []
synonym: "THIOUREA" EXACT [PDBeChem]
synonym: "Thiourea" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:51276 ! thioureas
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:23240 ! has role chromophore
relationship: RO:0018038 CHEBI:36958 ! has functional parent carbonothioic O,O-acid

[Term]
id: CHEBI:36958
name: carbonothioic O,O-acid
is_a: CHEBI:36960 ! carbonothioic acid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018036 CHEBI:36959 ! is tautomer of carbonothioic O,S-acid

[Term]
id: CHEBI:36959
name: carbonothioic O,S-acid
is_a: CHEBI:36960 ! carbonothioic acid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018036 CHEBI:36958 ! is tautomer of carbonothioic O,O-acid

[Term]
id: CHEBI:36960
name: carbonothioic acid
is_a: CHEBI:35605 ! carbon oxoacid
is_a: CHEBI:36961 ! chalcocarbonic acid

[Term]
id: CHEBI:36961
name: chalcocarbonic acid
is_a: CHEBI:36962 ! organochalcogen compound

[Term]
id: CHEBI:36962
name: organochalcogen compound
def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." []
is_a: CHEBI:33285 ! heteroorganic entity
is_a: CHEBI:33304 ! chalcogen molecular entity

[Term]
id: CHEBI:36963
name: organooxygen compound
def: "An organochalcogen compound containing at least one carbon-oxygen bond." []
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:36962 ! organochalcogen compound

[Term]
id: CHEBI:3697
name: cilastatin
def: "The thioether resulting from the formal oxidative coupling of the thiol group of <small>L</small>-cysteine with the 7-position of (2<i>Z</i>)-2-({[(1<i>S</i>)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin is therefore administered (as the sodium salt) with  imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to inactive and potentially nephrotoxic products. Cilastatin also acts as a leukotriene D<small><sub>4</sub></small> dipeptidase inhibitor, preventing the metabolism of leukotriene D<small><sub>4</sub></small> to leukotriene E<small><sub>4</sub></small>." []
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:51569 ! N-acyl-amino acid
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
is_a: CHEBI:83824 ! L-cysteine derivative
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37670 ! has role protease inhibitor
relationship: RO:0000087 CHEBI:76926 ! has role EC 3.4.13.19 (membrane dipeptidase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:59512 ! is protonated form of cilastatin(1-)

[Term]
id: CHEBI:36973
name: graphene
def: "A single carbon layer of the graphite structure, describing its nature by analogy to a polycyclic aromatic hydrocarbon of quasi infinite size." []
is_a: CHEBI:33415 ! elemental carbon

[Term]
id: CHEBI:36976
name: nucleotide
def: "A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid." []
is_a: CHEBI:25608 ! nucleoside phosphate

[Term]
id: CHEBI:36982
name: cyclic purine nucleotide
is_a: CHEBI:23447 ! cyclic nucleotide
is_a: CHEBI:26395 ! purine nucleotide

[Term]
id: CHEBI:36983
name: cyclic pyrimidine nucleotide
is_a: CHEBI:23447 ! cyclic nucleotide
is_a: CHEBI:26441 ! pyrimidine nucleotide

[Term]
id: CHEBI:36987
name: 3'-deoxyribonucleoside
is_a: CHEBI:23636 ! deoxyribonucleoside
is_a: CHEBI:47018 ! monohydroxytetrahydrofuran

[Term]
id: CHEBI:36988
name: 5'-deoxyribonucleoside
is_a: CHEBI:23636 ! deoxyribonucleoside

[Term]
id: CHEBI:37010
name: ribonucleoside 5'-monophosphate
is_a: CHEBI:26558 ! ribonucleoside monophosphate
is_a: CHEBI:37015 ! ribonucleoside 5'-phosphate

[Term]
id: CHEBI:37015
name: ribonucleoside 5'-phosphate
is_a: CHEBI:16701 ! nucleoside 5'-phosphate
is_a: CHEBI:26561 ! ribonucleotide

[Term]
id: CHEBI:37021
name: purine ribonucleoside 5'-monophosphate
is_a: CHEBI:26397 ! purine ribonucleoside monophosphate
is_a: CHEBI:26400 ! purine ribonucleotide
is_a: CHEBI:37010 ! ribonucleoside 5'-monophosphate

[Term]
id: CHEBI:37022
name: amino-acid anion
is_a: CHEBI:29067 ! carboxylic acid anion
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0018033 CHEBI:33709 ! is deprotonated form of amino acid

[Term]
id: CHEBI:37038
name: purine ribonucleoside 5'-diphosphate
is_a: CHEBI:26396 ! purine ribonucleoside diphosphate
is_a: CHEBI:26400 ! purine ribonucleotide
is_a: CHEBI:37075 ! ribonucleoside 5'-diphosphate

[Term]
id: CHEBI:37045
name: purine ribonucleoside 5'-triphosphate
is_a: CHEBI:26398 ! purine ribonucleoside triphosphate
is_a: CHEBI:26400 ! purine ribonucleotide
is_a: CHEBI:37076 ! ribonucleoside 5'-triphosphate

[Term]
id: CHEBI:37070
name: 2-methylbutyric acid
def: "A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria." []
is_a: CHEBI:38653 ! methylbutyric acid
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:48946 ! is protonated form of 2-methylbutyrate

[Term]
id: CHEBI:37075
name: ribonucleoside 5'-diphosphate
is_a: CHEBI:37015 ! ribonucleoside 5'-phosphate

[Term]
id: CHEBI:37076
name: ribonucleoside 5'-triphosphate
is_a: CHEBI:37015 ! ribonucleoside 5'-phosphate

[Term]
id: CHEBI:37080
name: acrylate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:18308 ! is deprotonated form of acrylic acid

[Term]
id: CHEBI:37086
name: C-nucleoside
is_a: CHEBI:20857 ! C-glycosyl compound

[Term]
id: CHEBI:37089
name: ortho-fused tricyclic hydrocarbon
is_a: CHEBI:35427 ! ortho-fused polycyclic hydrocarbon
is_a: CHEBI:51119 ! tricyclic hydrocarbon

[Term]
id: CHEBI:37096
name: adenosine 5'-phosphate
is_a: CHEBI:22256 ! adenosine phosphate

[Term]
id: CHEBI:37097
name: adenosine 3'-phosphate
is_a: CHEBI:22256 ! adenosine phosphate

[Term]
id: CHEBI:37110
name: thallium molecular entity
is_a: CHEBI:33581 ! boron group molecular entity
relationship: BFO:0000051 CHEBI:30440 ! has part thallium atom

[Term]
id: CHEBI:37111
name: gallium molecular entity
is_a: CHEBI:33581 ! boron group molecular entity
relationship: BFO:0000051 CHEBI:49631 ! has part gallium atom

[Term]
id: CHEBI:37112
name: indium molecular entity
is_a: CHEBI:33581 ! boron group molecular entity
relationship: BFO:0000051 CHEBI:30430 ! has part indium atom

[Term]
id: CHEBI:37113
name: elemental thallium
is_a: CHEBI:37110 ! thallium molecular entity

[Term]
id: CHEBI:37114
name: elemental indium
is_a: CHEBI:37112 ! indium molecular entity

[Term]
id: CHEBI:37121
name: guanosine 5'-phosphate
is_a: CHEBI:24455 ! guanosine phosphate

[Term]
id: CHEBI:37128
name: caesium molecular entity
is_a: CHEBI:33296 ! alkali metal molecular entity
relationship: BFO:0000051 CHEBI:30514 ! has part caesium atom

[Term]
id: CHEBI:37131
name: strontium molecular entity
is_a: CHEBI:33299 ! alkaline earth molecular entity
relationship: BFO:0000051 CHEBI:33324 ! has part strontium atom

[Term]
id: CHEBI:37133
name: barium molecular entity
is_a: CHEBI:33299 ! alkaline earth molecular entity
relationship: BFO:0000051 CHEBI:32594 ! has part barium atom

[Term]
id: CHEBI:37134
name: elemental barium
is_a: CHEBI:37133 ! barium molecular entity

[Term]
id: CHEBI:37141
name: organobromine compound
def: "A compound containing at least one carbon-bromine bond." []
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:22928 ! bromine molecular entity

[Term]
id: CHEBI:37142
name: organoiodine compound
def: "An organoiodine compound is a compound containing at least one carbon-iodine bond." []
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:24860 ! iodine molecular entity

[Term]
id: CHEBI:37143
name: organofluorine compound
def: "An organofluorine compound is a compound containing at least one carbon-fluorine bond." []
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:24062 ! fluorine molecular entity

[Term]
id: CHEBI:37144
name: epichlorohydrin
def: "An epoxide that is 1,2-epoxypropene in which one of the methyl hydrogens is substituted by chlorine." []
is_a: CHEBI:32955 ! epoxide
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0018038 CHEBI:38685 ! has functional parent 1,2-epoxypropane

[Term]
id: CHEBI:37147
name: dibromobenzene
def: "Any member of the class of bromobenzenes that consists of a benzene or a substituted benzene ring carrying two bromo groups at unspecified positions." []
is_a: CHEBI:37149 ! bromobenzenes

[Term]
id: CHEBI:37148
name: bromoarene
def: "A compound derived from an arene by replacing a hydrogen atom with a bromine atom." []
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:50887 ! haloarene

[Term]
id: CHEBI:37149
name: bromobenzenes
def: "A member of the class of benzenes that is benzene substituted by at least one bromo group." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:37151
name: 1,3-dibromobenzene
def: "A dibromobenzene carrying bromo groups at positions 1 and 3." []
is_a: CHEBI:37147 ! dibromobenzene

[Term]
id: CHEBI:37153
name: EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
def: "Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16)." []
is_a: CHEBI:76775 ! EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor

[Term]
id: CHEBI:37154
name: fumarate(1-)
def: "A hydrogen butenedioate obtained by deprotonation of one of the carboxy groups of fumaric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37155 ! hydrogen butenedioate
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:18012 ! is deprotonated form of fumaric acid
relationship: RO:0018034 CHEBI:29806 ! is protonated form of fumarate(2-)

[Term]
id: CHEBI:37155
name: hydrogen butenedioate
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:22958 ! is deprotonated form of butenedioic acid
relationship: RO:0018034 CHEBI:36180 ! is protonated form of butenedioate

[Term]
id: CHEBI:37156
name: maleate(1-)
def: "A hydrogen butenedioate that is the  conjugate base of maleic acid." []
is_a: CHEBI:132951 ! maleate
is_a: CHEBI:37155 ! hydrogen butenedioate
relationship: RO:0018034 CHEBI:30780 ! is protonated form of maleate(2-)

[Term]
id: CHEBI:37163
name: glucan
def: "A polysaccharide composed of glucose residues." []
synonym: "Glucan" EXACT [KEGG_COMPOUND]
is_a: CHEBI:37164 ! homopolysaccharide

[Term]
id: CHEBI:37164
name: homopolysaccharide
def: "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." []
is_a: CHEBI:18154 ! polysaccharide

[Term]
id: CHEBI:37165
name: galactan
def: "Polysaccharides composed of galactose residues." []
synonym: "Galactan" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37164 ! homopolysaccharide
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:37172
name: silanes
def: "Saturated silicon hydrides, analogues of the alkanes; i.e. compounds of the general formula Si<small><sub><em>n</em></sub></small>H<small><sub>2<em>n</em>+2</sub></small>." []
is_a: CHEBI:33329 ! silicon hydride

[Term]
id: CHEBI:37175
name: organic hydride
is_a: CHEBI:33692 ! hydrides

[Term]
id: CHEBI:37176
name: mononuclear parent hydride
is_a: CHEBI:33692 ! hydrides

[Term]
id: CHEBI:37184
name: lead hydride
is_a: CHEBI:37185 ! lead coordination entity
is_a: CHEBI:37761 ! metal hydride

[Term]
id: CHEBI:37185
name: lead coordination entity
is_a: CHEBI:33585 ! lead molecular entity
is_a: CHEBI:36562 ! main-group coordination entity

[Term]
id: CHEBI:37187
name: lead nitrate
is_a: CHEBI:37185 ! lead coordination entity
is_a: CHEBI:51084 ! inorganic nitrate salt

[Term]
id: CHEBI:37190
name: silicon coordination entity
is_a: CHEBI:26677 ! silicon molecular entity
is_a: CHEBI:36562 ! main-group coordination entity

[Term]
id: CHEBI:37191
name: silicon oxoanion
is_a: CHEBI:24834 ! inorganic anion
is_a: CHEBI:35406 ! oxoanion
is_a: CHEBI:37190 ! silicon coordination entity

[Term]
id: CHEBI:37193
name: elemental lead
is_a: CHEBI:33585 ! lead molecular entity

[Term]
id: CHEBI:37196
name: bismuth molecular entity
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: BFO:0000051 CHEBI:33301 ! has part bismuth atom

[Term]
id: CHEBI:37205
name: pentol
def: "A  polyol with five hydroxy groups." []
is_a: CHEBI:26191 ! polyol

[Term]
id: CHEBI:37206
name: hexol
def: "A polyol that contains 6 hydroxy groups." []
is_a: CHEBI:26191 ! polyol

[Term]
id: CHEBI:37217
name: titanium molecular entity
is_a: CHEBI:33768 ! titanium group molecular entity
relationship: BFO:0000051 CHEBI:33341 ! has part titanium atom

[Term]
id: CHEBI:37228
name: iridium molecular entity
is_a: CHEBI:33767 ! cobalt group molecular entity
relationship: BFO:0000051 CHEBI:49666 ! has part iridium atom

[Term]
id: CHEBI:3723
name: citalopram
def: "A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer,  escitalopram. It is used as an antidepressant, although only escitalopram is active." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:36791 ! has part escitalopram
relationship: BFO:0000051 CHEBI:36792 ! has part (R)-citalopram
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0000087 CHEBI:77402 ! has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:37246
name: elemental sodium
is_a: CHEBI:26712 ! sodium molecular entity

[Term]
id: CHEBI:37247
name: elemental potassium
is_a: CHEBI:26217 ! potassium molecular entity

[Term]
id: CHEBI:37253
name: elemental zinc
is_a: CHEBI:27364 ! zinc molecular entity

[Term]
id: CHEBI:37293
name: 1-ribosylimidazole
is_a: CHEBI:48117 ! 1-glycosylimidazole

[Term]
id: CHEBI:37302
name: thorium molecular entity
def: "An actinoid molecular entity containing at least one atome of thorium." []
is_a: CHEBI:33498 ! actinoid molecular entity
relationship: BFO:0000051 CHEBI:33385 ! has part thorium

[Term]
id: CHEBI:3732
name: clarithromycin
def: "The 6-<em>O</em>-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate <em>Helicobacter pylori</em> in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis." []
is_a: CHEBI:25105 ! macrolide antibiotic
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:37323
name: 7,8-dimethylisoalloxazine
def: "A 7,8-dimethylbenzo[<em>g</em>]pteridine-2,4-dione that is  isoalloxazine substituted by methyl groups at positions 7 and 8." []
is_a: CHEBI:37324 ! 7,8-dimethylbenzo[g]pteridine-2,4-dione
relationship: RO:0018036 CHEBI:17781 ! is tautomer of lumichrome
relationship: RO:0018038 CHEBI:37327 ! has functional parent isoalloxazine

[Term]
id: CHEBI:37324
name: 7,8-dimethylbenzo[g]pteridine-2,4-dione
is_a: CHEBI:38925 ! benzopteridine

[Term]
id: CHEBI:37325
name: alloxazine
is_a: CHEBI:37326 ! benzo[g]pteridine-2,4-dione
relationship: RO:0018036 CHEBI:37327 ! is tautomer of isoalloxazine

[Term]
id: CHEBI:37326
name: benzo[g]pteridine-2,4-dione
is_a: CHEBI:38925 ! benzopteridine

[Term]
id: CHEBI:37327
name: isoalloxazine
is_a: CHEBI:37326 ! benzo[g]pteridine-2,4-dione
relationship: RO:0018036 CHEBI:37325 ! is tautomer of alloxazine

[Term]
id: CHEBI:37332
name: tropane alkaloid
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:38295 ! azabicycloalkane

[Term]
id: CHEBI:37334
name: diagnostic imaging agent
def: "A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, γ-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease." []
is_a: CHEBI:33295 ! diagnostic agent

[Term]
id: CHEBI:37335
name: MRI contrast agent
is_a: CHEBI:37334 ! diagnostic imaging agent

[Term]
id: CHEBI:37337
name: ultrasound contrast agent
is_a: CHEBI:37334 ! diagnostic imaging agent

[Term]
id: CHEBI:37338
name: radioopaque medium
def: "A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays." []
is_a: CHEBI:37334 ! diagnostic imaging agent

[Term]
id: CHEBI:37339
name: thorium dioxide
is_a: CHEBI:37302 ! thorium molecular entity

[Term]
id: CHEBI:37378
name: phosphorus halide
is_a: CHEBI:37380 ! pnictogen halide
is_a: CHEBI:50536 ! phosphorus coordination entity

[Term]
id: CHEBI:37380
name: pnictogen halide
is_a: CHEBI:33302 ! pnictogen molecular entity

[Term]
id: CHEBI:37381
name: nitrogen halide
is_a: CHEBI:37380 ! pnictogen halide
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:37395
name: mucopolysaccharide
def: "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." []
is_a: CHEBI:18085 ! glycosaminoglycan

[Term]
id: CHEBI:37403
name: copper coordination entity
is_a: CHEBI:23377 ! copper molecular entity
is_a: CHEBI:33861 ! transition element coordination entity

[Term]
id: CHEBI:37404
name: elemental copper
is_a: CHEBI:23377 ! copper molecular entity

[Term]
id: CHEBI:37407
name: cyclic ether
def: "Any ether in which the oxygen atom forms part of a ring." []
synonym: "cyclic ethers" EXACT [ChEBI]
is_a: CHEBI:25698 ! ether
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:37415
name: alpha-amanitin
def: "A heterodetic cyclic peptide consisting of eight amino acid residues and containing a thioether bridge between a cysteine and a tryptophan residue. It is found in a number of poisonous mushrooms, including <em>Amanita phalloides</em> (the death cap), <em>Galerina marginata</em>, and <em>and Conocybe filaris</em>." []
is_a: CHEBI:24533 ! heterodetic cyclic peptide
relationship: RO:0000087 CHEBI:25442 ! has role mycotoxin
relationship: RO:0000087 CHEBI:37416 ! has role EC 2.7.7.6 (RNA polymerase) inhibitor

[Term]
id: CHEBI:37416
name: EC 2.7.7.6 (RNA polymerase) inhibitor
def: "An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6)." []
is_a: CHEBI:76815 ! EC 2.7.7.* (nucleotidyltransferase) inhibitor

[Term]
id: CHEBI:37429
name: aldonolactone phosphate
is_a: CHEBI:26816 ! carbohydrate phosphate

[Term]
id: CHEBI:37445
name: folic acids
def: "A group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more <small>L</small>-glutamic acid units." []
is_a: CHEBI:176842 ! vitamin B9
is_a: CHEBI:26375 ! pterins
is_a: CHEBI:83982 ! L-glutamic acid derivative
relationship: RO:0018034 CHEBI:67011 ! is protonated form of folates

[Term]
id: CHEBI:3745
name: clindamycin
def: "A carbohydrate-containing antibiotic that is the  semisynthetic derivative of lincomycin, a natural antibiotic." []
is_a: CHEBI:23007 ! carbohydrate-containing antibiotic
is_a: CHEBI:35275 ! S-glycosyl compound
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:46770 ! pyrrolidinecarboxamide
is_a: CHEBI:72588 ! semisynthetic derivative
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:6472 ! has functional parent lincomycin

[Term]
id: CHEBI:37484
name: dihydroxyanthraquinone
is_a: CHEBI:37485 ! hydroxyanthraquinones

[Term]
id: CHEBI:37485
name: hydroxyanthraquinones
def: "An anthraquinone substituted with one or more hydroxy groups." []
is_a: CHEBI:22580 ! anthraquinone
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:37488
name: trihydroxyanthraquinone
def: "A member of the class of  hydroxyanthraquinones carrying three hydroxy substituents." []
is_a: CHEBI:37485 ! hydroxyanthraquinones

[Term]
id: CHEBI:37494
name: alkenyl phosphate
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:37734 ! phosphoric ester

[Term]
id: CHEBI:3751
name: clomazone
def: "An isoxazolidinone that is 1,2-oxazolidin-3-one substituted by a 2-chlorobenzyl group at position 2 and two methyl groups at position 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:55375 ! isoxazolidinone
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:138208 ! has role carotenoid biosynthesis inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:37511
name: thiophosphate
is_a: CHEBI:26020 ! phosphate

[Term]
id: CHEBI:37512
name: organic thiophosphate
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:25716 ! organothiophosphorus compound
is_a: CHEBI:37511 ! thiophosphate
is_a: CHEBI:37734 ! phosphoric ester

[Term]
id: CHEBI:37514
name: purine arabinonucleoside monophosphate
def: "A purine nucleoside monophosphate in which the sugar component is specified as arabinosyl." []
is_a: CHEBI:26392 ! purine nucleoside monophosphate

[Term]
id: CHEBI:37526
name: tigliane
is_a: CHEBI:35190 ! diterpene
is_a: CHEBI:35662 ! terpenoid fundamental parent

[Term]
id: CHEBI:37527
name: acid
def: "An acid is a molecular entity capable of donating a hydron (Brønsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." []
synonym: "Acid" EXACT [KEGG_COMPOUND]
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:37529
name: cyclohexenecarboxylate ester
is_a: CHEBI:51702 ! enoate ester
relationship: RO:0018038 CHEBI:23483 ! has functional parent cyclohexenecarboxylic acid

[Term]
id: CHEBI:37532
name: phorbol ester
def: "Esters of phorbol, originally found in croton oil (from <em>Croton tiglium</em>, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:52557 ! tetracyclic diterpenoid
relationship: RO:0018038 CHEBI:8116 ! has functional parent phorbol

[Term]
id: CHEBI:37533
name: azo compound
def: "Derivatives of diazene with the general structure R‒N=N‒R'." []
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: BFO:0000051 CHEBI:30106 ! has part azo group
relationship: RO:0018040 CHEBI:30096 ! has parent hydride diazene

[Term]
id: CHEBI:37537
name: phorbol 13-acetate 12-myristate
def: "A phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted into the corresponding acetate and myristate esters. It is a major active constituent of the seed oil of <em>Croton tiglium</em>. It has been used as a tumour promoting agent for skin carcinogenesis in rodents and is associated with increased cell proliferation of malignant cells. However its function is controversial since a decrease in cell proliferation has also been observed in several cancer cell types." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:37532 ! phorbol ester
is_a: CHEBI:47622 ! acetate ester
is_a: CHEBI:51307 ! diester
is_a: CHEBI:87691 ! tetradecanoate ester
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:52290 ! has role mitogen
relationship: RO:0000087 CHEBI:64018 ! has role protein kinase C agonist
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:70982 ! has role reactive oxygen species generator
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:37558
name: aryl dialkyl phosphate
def: "Any aryl phosphate having a single aryl substituent and two alkyl substituents." []
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:36943 ! aryl phosphate

[Term]
id: CHEBI:37562
name: trialkyl phosphate
is_a: CHEBI:22324 ! alkyl phosphate

[Term]
id: CHEBI:37577
name: heteroatomic molecular entity
def: "A molecular entity consisting of two or more chemical elements." []
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:37578
name: halide
def: "Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements." []
is_a: CHEBI:24471 ! halogen molecular entity
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:37579
name: acyl halide
def: "A compound consisting of an acyl group bonded to halogen." []
is_a: CHEBI:37578 ! halide

[Term]
id: CHEBI:37581
name: gamma-lactone
def: "A lactone having a five-membered lactone ring." []
is_a: CHEBI:25000 ! lactone

[Term]
id: CHEBI:37586
name: sodium phosphate
is_a: CHEBI:190300 ! inorganic phosphate salt
is_a: CHEBI:24838 ! inorganic phosphate
is_a: CHEBI:38702 ! inorganic sodium salt

[Term]
id: CHEBI:37588
name: phosphonic acid derivative
is_a: CHEBI:36359 ! phosphorus oxoacid derivative
relationship: RO:0018038 CHEBI:44976 ! has functional parent phosphonic acid

[Term]
id: CHEBI:37592
name: organic phosphonate
is_a: CHEBI:25710 ! organophosphorus compound
is_a: CHEBI:26066 ! phosphonate

[Term]
id: CHEBI:37598
name: nitrogen mustard
def: "Compounds having two β-haloalkyl groups bound to a nitrogen atom, as in (X‒CH<small><sub>2</sub></small>‒CH<small><sub>2</sub></small>)<small><sub>2</sub></small>NR." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent

[Term]
id: CHEBI:37604
name: cis-octadec-9-ene
is_a: CHEBI:37605 ! octadec-9-ene

[Term]
id: CHEBI:37605
name: octadec-9-ene
is_a: CHEBI:37606 ! octadecene

[Term]
id: CHEBI:37606
name: octadecene
def: "An alkene that is octadecane containing one double bond at unspecified position." []
is_a: CHEBI:32878 ! alkene

[Term]
id: CHEBI:37622
name: carboxamide
def: "An amide of a carboxylic acid, having the structure RC(=O)NR<small><sub>2</sub></small>. The term is used as a suffix in systematic name formation to denote the ‒C(=O)NH<small><sub>2</sub></small> group including its carbon atom." []
is_a: CHEBI:33256 ! primary amide
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: BFO:0000051 CHEBI:23004 ! has part carbamoyl group

[Term]
id: CHEBI:37624
name: L-glucose
is_a: CHEBI:17234 ! glucose

[Term]
id: CHEBI:37627
name: L-glucopyranose
def: "The <small>L</small>-enantiomer of glucopyranose." []
is_a: CHEBI:37624 ! L-glucose
is_a: CHEBI:37661 ! glucopyranose

[Term]
id: CHEBI:37631
name: beta-L-glucose
def: "A <small>L</small>-glucopyranose with a β-configuration at the anomeric position." []
is_a: CHEBI:37627 ! L-glucopyranose
relationship: RO:0018039 CHEBI:15903 ! is enantiomer of beta-D-glucose

[Term]
id: CHEBI:3764
name: clotrimazole
def: "A member of the class of imidazoles that is 1<em>H</em>-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group." []
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:87069 ! imidazole antifungal drug
is_a: CHEBI:87071 ! conazole antifungal drug
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:37659
name: oleanolic acid
def: "A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a β-hydroxy group at position 3." []
is_a: CHEBI:25872 ! pentacyclic triterpenoid
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:82828 ! is protonated form of oleanolate
relationship: RO:0018040 CHEBI:36481 ! has parent hydride oleanane

[Term]
id: CHEBI:3766
name: clozapine
def: "A benzodiazepine that is 5<em>H</em>-dibenzo[<em>b,e</em>][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like  schizophrenia." []
is_a: CHEBI:22720 ! benzodiazepine
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:46920 ! N-methylpiperazine
is_a: CHEBI:64051 ! dibenzodiazepine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37887 ! has role adrenergic antagonist
relationship: RO:0000087 CHEBI:37956 ! has role histamine antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:48876 ! has role muscarinic antagonist
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic
relationship: RO:0000087 CHEBI:65259 ! has role GABA antagonist
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:37661
name: glucopyranose
is_a: CHEBI:17234 ! glucose

[Term]
id: CHEBI:37667
name: sesquiterpene lactone
def: "Any member of a diverse class of complex, multicyclic phytochemicals showing a variety of skeleton arrangements and bioactivities, and having in common a sesquiterpenoid structure including a lactone ring." []
is_a: CHEBI:26658 ! sesquiterpenoid
is_a: CHEBI:37668 ! terpene lactone

[Term]
id: CHEBI:37668
name: terpene lactone
is_a: CHEBI:25000 ! lactone
is_a: CHEBI:26873 ! terpenoid

[Term]
id: CHEBI:37670
name: protease inhibitor
def: "A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:37684
name: mannose
def: "An aldohexose that is the C-2 epimer of glucose." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33917 ! aldohexose
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:37697
name: indolocarbazole alkaloid
is_a: CHEBI:38958 ! indole alkaloid
is_a: CHEBI:51915 ! indolocarbazole

[Term]
id: CHEBI:37699
name: protein kinase inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of protein kinases." []
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:37700
name: EC 2.7.11.13 (protein kinase C) inhibitor
def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13)." []
is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor

[Term]
id: CHEBI:37716
name: mixed diacylamine
def: "Any imide in which the acyl substituents are any two from carboacyl, sulfonyl and phosphoryl" []
is_a: CHEBI:24782 ! imide

[Term]
id: CHEBI:37733
name: EC 3.1.1.8 (cholinesterase) inhibitor
def: "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8)." []
is_a: CHEBI:76773 ! EC 3.1.1.* (carboxylic ester hydrolase) inhibitor

[Term]
id: CHEBI:37734
name: phosphoric ester
is_a: CHEBI:26079 ! phosphoric acid derivative
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:37735
name: phosphonic ester
def: "A phosphonic acid derivative in which one or both OH groups have been esterified." []
is_a: CHEBI:35701 ! ester
is_a: CHEBI:37588 ! phosphonic acid derivative

[Term]
id: CHEBI:37739
name: glycerophospholipid
def: "Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone." []
is_a: CHEBI:16247 ! phospholipid
is_a: CHEBI:35741 ! glycerolipid

[Term]
id: CHEBI:37749
name: halogen oxide
is_a: CHEBI:24471 ! halogen molecular entity
is_a: CHEBI:24836 ! inorganic oxide

[Term]
id: CHEBI:37750
name: chlorine oxide
is_a: CHEBI:37749 ! halogen oxide

[Term]
id: CHEBI:37757
name: iodoalkane
def: "Any haloalkane carrying at least one iodo group." []
is_a: CHEBI:24469 ! haloalkane

[Term]
id: CHEBI:37758
name: iodoform
is_a: CHEBI:39284 ! iodomethanes

[Term]
id: CHEBI:37761
name: metal hydride
is_a: CHEBI:33242 ! inorganic hydride

[Term]
id: CHEBI:37765
name: halohalide
is_a: CHEBI:24471 ! halogen molecular entity

[Term]
id: CHEBI:37775
name: molybdenum oxide
is_a: CHEBI:35202 ! molybdenum coordination entity

[Term]
id: CHEBI:37784
name: sulfinic acid derivative
is_a: CHEBI:33424 ! sulfur oxoacid derivative
relationship: RO:0018038 CHEBI:29213 ! has functional parent sulfinic acid

[Term]
id: CHEBI:37786
name: acyclic phosphorus acid anhydride
is_a: CHEBI:36608 ! acyclic acid anhydride

[Term]
id: CHEBI:37793
name: amino sulfonic acid
def: "An organosulfonic acid containing one or more amino groups." []
is_a: CHEBI:33551 ! organosulfonic acid
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:37806
name: penicillanic acid
def: "A penam that consists of 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane bearing a carboxy group at position 2 and having (2<i>S</i>,5<i>R</i>)-configuration." []
is_a: CHEBI:25865 ! penicillanic acids

[Term]
id: CHEBI:37808
name: butane
def: "A straight chain alkane composed of 4 carbon atoms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:78017 ! has role food propellant
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:37825
name: p-toluidine
def: "An aminotoluene in which the amino substituent is <em>para</em> to the methyl group." []
is_a: CHEBI:22531 ! aminotoluene

[Term]
id: CHEBI:37826
name: sulfuric acid derivative
is_a: CHEBI:33424 ! sulfur oxoacid derivative
relationship: RO:0018038 CHEBI:26836 ! has functional parent sulfuric acid

[Term]
id: CHEBI:37830
name: pentane
def: "A straight chain alkane consisting of 5 carbon atoms." []
synonym: "PENTANE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:37834
name: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraene
is_a: CHEBI:37835 ! alkatetraene

[Term]
id: CHEBI:37835
name: alkatetraene
def: "Acyclic branched or unbranched hydrocarbons having four carbon-carbon double bonds." []
is_a: CHEBI:33645 ! acyclic olefin

[Term]
id: CHEBI:37838
name: carboacyl group
def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." []
is_a: CHEBI:22221 ! acyl group
relationship: RO:0018037 CHEBI:33575 ! is substitutent group from carboxylic acid

[Term]
id: CHEBI:37845
name: growth hormone
def: "A hormone that specifically regulates growth." []
is_a: CHEBI:24621 ! hormone

[Term]
id: CHEBI:37848
name: plant hormone
def: "A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds." []
is_a: CHEBI:24621 ! hormone
is_a: CHEBI:26155 ! plant growth regulator

[Term]
id: CHEBI:37852
name: organoammonium sulfate salt
is_a: CHEBI:46850 ! organoammonium salt
is_a: CHEBI:51337 ! organic sulfate salt

[Term]
id: CHEBI:37853
name: phosphate salt
is_a: CHEBI:26020 ! phosphate

[Term]
id: CHEBI:37863
name: chalcoperoxol
is_a: CHEBI:36962 ! organochalcogen compound

[Term]
id: CHEBI:37886
name: adrenergic agonist
def: "An agent that selectively binds to and activates adrenergic receptors." []
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:37887
name: adrenergic antagonist
def: "An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists." []
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:37890
name: alpha-adrenergic antagonist
def: "An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma." []
is_a: CHEBI:37887 ! adrenergic antagonist
is_a: CHEBI:48539 ! alpha-adrenergic drug

[Term]
id: CHEBI:37910
name: indene
is_a: CHEBI:35428 ! ortho-fused bicyclic hydrocarbon

[Term]
id: CHEBI:37912
name: hydroxycoumarin
def: "Any coumarin carrying at least one hydroxy substituent." []
is_a: CHEBI:23403 ! coumarins

[Term]
id: CHEBI:37919
name: aryl sulfate
is_a: CHEBI:25704 ! organic sulfate
is_a: CHEBI:26819 ! sulfuric ester
relationship: RO:0018033 CHEBI:139371 ! is deprotonated form of aryl sulfate oxoanion

[Term]
id: CHEBI:37921
name: pyridazines
is_a: CHEBI:38313 ! diazines

[Term]
id: CHEBI:37924
name: atazanavir
def: "A heavily substituted carbohydrazide that is an antiretroviral drug of the protease inhibitor (PI) class used to treat infection of human immunodeficiency virus (HIV)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27267 ! valine derivative
is_a: CHEBI:35363 ! carbohydrazide
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35660 ! has role HIV protease inhibitor
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug

[Term]
id: CHEBI:37929
name: xanthene dye
def: "A dye derived by condensation of phthalic anhydride with resorcinol (and derivatives) or <em>m</em>-aminophenol (and derivatives)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38835 ! xanthenes
relationship: RO:0000087 CHEBI:37958 ! has role dye

[Term]
id: CHEBI:37930
name: phenothiazine antipsychotic drug
is_a: CHEBI:65190 ! first generation antipsychotic

[Term]
id: CHEBI:37931
name: 10H-phenothiazine
def: "The 10<em>H</em>-tautomer of phenothiazine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37932 ! phenothiazine
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018036 CHEBI:37933 ! is tautomer of 4aH-phenothiazine
relationship: RO:0018036 CHEBI:37934 ! is tautomer of 1H-phenothiazine
relationship: RO:0018036 CHEBI:37935 ! is tautomer of 3H-phenothiazine

[Term]
id: CHEBI:37932
name: phenothiazine
is_a: CHEBI:36416 ! mancude organic heterotricyclic parent
is_a: CHEBI:38093 ! phenothiazines

[Term]
id: CHEBI:37933
name: 4aH-phenothiazine
is_a: CHEBI:37932 ! phenothiazine
relationship: RO:0018036 CHEBI:37931 ! is tautomer of 10H-phenothiazine
relationship: RO:0018036 CHEBI:37934 ! is tautomer of 1H-phenothiazine
relationship: RO:0018036 CHEBI:37935 ! is tautomer of 3H-phenothiazine

[Term]
id: CHEBI:37934
name: 1H-phenothiazine
is_a: CHEBI:37932 ! phenothiazine
relationship: RO:0018036 CHEBI:37931 ! is tautomer of 10H-phenothiazine
relationship: RO:0018036 CHEBI:37933 ! is tautomer of 4aH-phenothiazine
relationship: RO:0018036 CHEBI:37935 ! is tautomer of 3H-phenothiazine

[Term]
id: CHEBI:37935
name: 3H-phenothiazine
is_a: CHEBI:37932 ! phenothiazine
relationship: RO:0018036 CHEBI:37931 ! is tautomer of 10H-phenothiazine
relationship: RO:0018036 CHEBI:37933 ! is tautomer of 4aH-phenothiazine
relationship: RO:0018036 CHEBI:37934 ! is tautomer of 1H-phenothiazine

[Term]
id: CHEBI:37941
name: clopidogrel
def: "A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-<em>c</em>]pyridine in which the hydrogen attached to the nitrogen is replaced by an <em>o</em>-chlorobenzyl group, the methylene hydrogen of which is replaced by a  methoxycarbonyl group (the <i>S</i> enantiomer). A P2Y<small><sub>12</sub></small> receptor antagonist, it is used to inhibit blood clots and prevent heart attacks." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:37942 ! thienopyridine
is_a: CHEBI:46874 ! alpha-amino acid ester
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:68563 ! has role P2Y12 receptor antagonist
relationship: RO:0018038 CHEBI:9588 ! has functional parent ticlopidine

[Term]
id: CHEBI:37942
name: thienopyridine
def: "Any organic heterobicyclic compound whose skeleton results from the formal <em>ortho</em>-fusion of any bond of a pyridine with any bond of a thiophene." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:37943
name: colistin
def: "A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of <em>Bacillus polymyxa</em> var. <em>colistinus</em>. An antibiotic, it is used as its sulfate salt (for oral or topical use) or as the sodium salt of the <em>N</em>-methylsulfonic acid derivative (the injectable form) in the treatment of severe Gram-negative infections, partiularly those due to <em>Pseudomonas aeruginosa</em>." []
is_a: CHEBI:25903 ! peptide antibiotic
is_a: CHEBI:59062 ! polymyxin
relationship: BFO:0000051 CHEBI:59064 ! has part colistin A
relationship: BFO:0000051 CHEBI:59673 ! has part colistin B
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50909 ! has role nephrotoxic agent

[Term]
id: CHEBI:37944
name: polysaccharide sulfate
def: "Any carbohydrate sulfate that is a polysaccharide carrying at least one O-sulfo substituent." []
is_a: CHEBI:35724 ! carbohydrate sulfate
is_a: CHEBI:65212 ! polysaccharide derivative

[Term]
id: CHEBI:37947
name: benzothiazoles
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:37948
name: oxaspiro compound
def: "A spiro compound in which at least one of the cyclic components is an oxygen heterocyle." []
is_a: CHEBI:33599 ! spiro compound

[Term]
id: CHEBI:37949
name: azacycloalkane
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:37955
name: H1-receptor antagonist
def: "H<small><sub>1</sub></small>-receptor antagonists are the drugs that selectively bind to but do not activate histamine H<small><sub>1</sub></small> receptors, thereby blocking the actions of endogenous histamine." []
is_a: CHEBI:37956 ! histamine antagonist

[Term]
id: CHEBI:37956
name: histamine antagonist
def: "Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists." []
is_a: CHEBI:37957 ! histaminergic drug
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:37957
name: histaminergic drug
def: "Drugs used for their actions on histaminergic systems." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:37958
name: dye
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:37960
name: cyanine dye
def: "Cyanine dyes are synthetic dyes with the general formula R<small><sub>2</sub></small>N[CH=CH]<small><sub><em>n</em></sub></small>CH=N<small><sup>+</small></sup>R<small><sub>2</sub></small>    ↔ R<small><sub>2</sub></small>N<small><sup>+</small></sup>=CH[CH=CH]<small><sub><em>n</em></sub></small>NR<small><sub>2</sub></small> (<em>n</em> is a small number) in which the nitrogen and part of the conjugated chain usually form part of a heterocyclic system, such as imidazole, pyridine, pyrrole, quinoline and thiazole." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:37958 ! has role dye

[Term]
id: CHEBI:37961
name: H2-receptor antagonist
def: "H<small><sub>2</sub></small>-receptor antagonists are the drugs that selectively bind to but do not activate histamine H<small><sub>2</sub></small> receptors, thereby blocking the actions of endogenous histamine." []
is_a: CHEBI:37956 ! histamine antagonist

[Term]
id: CHEBI:37962
name: adrenergic agent
def: "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:37963
name: pyranone
def: "Any of a class of cyclic chemical compounds that contain an unsaturated six-membered ring with one ring oxygen atom and an oxo substituent." []
is_a: CHEBI:26407 ! pyrans

[Term]
id: CHEBI:37997
name: homopolymer macromolecule
def: "A macromolecule derived from one species of (real, implicit or hypothetical) monomer." []
is_a: CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:38001
name: 2,6-diaminopurines
def: "Any aminopurine that has amino substituents at positions 2 and 6, and their substituted derivatives." []
is_a: CHEBI:22527 ! aminopurine

[Term]
id: CHEBI:38011
name: 1,2,4-benzotriazine
is_a: CHEBI:39097 ! benzotriazine

[Term]
id: CHEBI:38012
name: aminoglycoside sulfate salt
is_a: CHEBI:37852 ! organoammonium sulfate salt

[Term]
id: CHEBI:38032
name: carbotricyclic compound
def: "A carbopolyclic compound comprising of three carbocyclic rings." []
is_a: CHEBI:35294 ! carbopolycyclic compound
is_a: CHEBI:51959 ! organic tricyclic compound

[Term]
id: CHEBI:38034
name: aminonaphthalene
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:33860 ! aromatic amine

[Term]
id: CHEBI:38044
name: trioxane
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:38056
name: triazine
def: "Any of three isomers generated by replacing three of the carbon atoms of benzene with nitrogen atoms." []
is_a: CHEBI:35555 ! mancude organic heteromonocyclic parent
is_a: CHEBI:38102 ! triazines
is_a: CHEBI:38179 ! monocyclic heteroarene

[Term]
id: CHEBI:38060
name: triazine insecticide
is_a: CHEBI:24852 ! insecticide

[Term]
id: CHEBI:38067
name: propazine
def: "A  diamino-1,3,5-triazine that is <em>N</em>,<em>N</em>'-di(propan-2-yl)-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6." []
is_a: CHEBI:38168 ! chloro-1,3,5-triazine
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:38068
name: antimalarial
def: "A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against <em>Plasmodia</em> at different stages in their life cycle in the human." []
is_a: CHEBI:64915 ! antiplasmodial drug

[Term]
id: CHEBI:38069
name: cyanazine
def: "A chloro-1,3,5-triazine that is 2-chloro-1,3,5-triazine substituted by an ethyl amino and a (2-cyanopropan-2-yl)amino group at positions 6 and 4 respectively." []
is_a: CHEBI:38168 ! chloro-1,3,5-triazine
is_a: CHEBI:38176 ! 1,3,5-triazinylamino nitrile
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:38070
name: anti-arrhythmia drug
def: "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres." []
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:38071
name: 1,3,5-triazine-2,4-diamine
is_a: CHEBI:38170 ! diamino-1,3,5-triazine

[Term]
id: CHEBI:38074
name: 2-chloro-1,3,5-triazine
is_a: CHEBI:38168 ! chloro-1,3,5-triazine

[Term]
id: CHEBI:38077
name: polypyrrole
def: "A compound composed of two or more pyrrole units." []
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38079
name: 1,3-dithiolane
is_a: CHEBI:38335 ! dithiolane

[Term]
id: CHEBI:38083
name: malonate ester
def: "An ester of malonic acid; any compound containing a malonate ester skeleton." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:30794 ! has functional parent malonic acid

[Term]
id: CHEBI:38084
name: sulfoximide
def: "Compounds having the structure R<small><sub></sub></small>S(=O)=NR." []
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:38085
name: 2-benzofuran-1(3H)-one
def: "A γ-lactone that is 1,3-dihydro-2-benzofuran in which the hydrogens at position 1 are replaced by an oxo group." []
is_a: CHEBI:37581 ! gamma-lactone
is_a: CHEBI:38831 ! 2-benzofurans

[Term]
id: CHEBI:38088
name: sultone
def: "An intramolecular cyclic ester of a hydroxy sulfonic acid, analogous to lactone." []
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:38092
name: cardenolide glycoside
def: "Any member of the class of cardenolides with glycosyl residues attached to position 3." []
is_a: CHEBI:74634 ! cardenolides
is_a: CHEBI:83970 ! cardiac glycoside

[Term]
id: CHEBI:38093
name: phenothiazines
is_a: CHEBI:26979 ! organic heterotricyclic compound

[Term]
id: CHEBI:38099
name: thiadiazoles
is_a: CHEBI:25693 ! organic heteromonocyclic compound

[Term]
id: CHEBI:38101
name: organonitrogen heterocyclic compound
def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." []
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:38102
name: triazines
def: "Compounds based on a triazine skeleton." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:50893 ! azaarene

[Term]
id: CHEBI:38104
name: oxacycle
def: "Any organic heterocyclic compound containing at least one ring oxygen atom." []
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:38105
name: gitoxigenin
is_a: CHEBI:17354 ! 16beta-hydroxy steroid
is_a: CHEBI:36836 ! 3beta-hydroxy steroid
is_a: CHEBI:36862 ! 14beta-hydroxy steroid
relationship: RO:0018040 CHEBI:35542 ! has parent hydride 5beta-cardanolide

[Term]
id: CHEBI:38106
name: organosulfur heterocyclic compound
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:38124
name: dialdehyde
def: "Any aldehyde with two aldehyde groups." []
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:38127
name: thiocarbamic ester
def: "Any organonitrogen compound with formula RS-C(=X)NH<small><sub>2</sub></small> where X = O (monothiocarbamic esters) or S (dithiocarbamic esters), or their <em>N</em>-substituted derivatives." []
is_a: CHEBI:26959 ! thiocarboxylic ester
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:38128
name: monothiocarbamic ester
def: "A thiocarbamic ester formally derived from a monothiocarbamic acid." []
is_a: CHEBI:38127 ! thiocarbamic ester

[Term]
id: CHEBI:38129
name: dithiocarbamic ester
def: "Any ester derived from a member of the class of dithiocarbamic acids by formal replacement of the -SH group by -SR, where R is an organyl group." []
is_a: CHEBI:38127 ! thiocarbamic ester

[Term]
id: CHEBI:38131
name: lactol
def: "Cyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues." []
is_a: CHEBI:5653 ! hemiacetal

[Term]
id: CHEBI:38147
name: cardiotonic drug
def: "A drug that has a strengthening effect on the heart or that can increase cardiac output." []
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:3815
name: Collagen
is_a: CHEBI:60027 ! polymer

[Term]
id: CHEBI:38155
name: phytosiderophore
def: "Any of low-molecular-mass iron(III)-chelating compounds produced by plants for the purpose of the transport and sequestration of iron." []
is_a: CHEBI:24028 ! iron(3+) chelator
is_a: CHEBI:24874 ! iron ionophore

[Term]
id: CHEBI:38157
name: iron chelator
is_a: CHEBI:38161 ! chelator

[Term]
id: CHEBI:38161
name: chelator
def: "A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate." []
is_a: CHEBI:52214 ! ligand

[Term]
id: CHEBI:38162
name: iron(2+) chelator
is_a: CHEBI:38157 ! iron chelator

[Term]
id: CHEBI:38163
name: organic heterotetracyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:38164
name: organic heteropentacyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:38165
name: organic heterooctacyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:38166
name: organic heteropolycyclic compound
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:33671 ! heteropolycyclic compound

[Term]
id: CHEBI:38168
name: chloro-1,3,5-triazine
def: "A member of the class of 1,3,5-triazines that is 1,3,5-triazine substituted by at least one chloro group at unspecified position." []
is_a: CHEBI:26588 ! 1,3,5-triazines
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:38170
name: diamino-1,3,5-triazine
def: "Any member of the class of 1,3,5-triazines that consists of a 1,3,5-triazine skeleton substituted by two amino groups." []
is_a: CHEBI:23666 ! diamine
is_a: CHEBI:26588 ! 1,3,5-triazines

[Term]
id: CHEBI:38174
name: methylthio-1,3,5-triazine
is_a: CHEBI:26588 ! 1,3,5-triazines
is_a: CHEBI:86315 ! methyl sulfide

[Term]
id: CHEBI:38175
name: triamino-1,3,5-triazine
is_a: CHEBI:26588 ! 1,3,5-triazines

[Term]
id: CHEBI:38176
name: 1,3,5-triazinylamino nitrile
def: "Any diamino-1,3,5-triazine in which the amino group is substituted by at least one cyano group." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:38170 ! diamino-1,3,5-triazine

[Term]
id: CHEBI:38177
name: methoxy-1,3,5-triazine
def: "Any member of the class of 1,3,5-triazines substituted by at least one methoxy group." []
is_a: CHEBI:26588 ! 1,3,5-triazines
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:38179
name: monocyclic heteroarene
is_a: CHEBI:33833 ! heteroarene

[Term]
id: CHEBI:38180
name: polycyclic heteroarene
is_a: CHEBI:33833 ! heteroarene

[Term]
id: CHEBI:38181
name: pyridinemonocarboxylate
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of a pyridinemonocarboxylic acid. A 'closed class'." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:26420 ! is deprotonated form of pyridinemonocarboxylic acid

[Term]
id: CHEBI:38183
name: pyridone
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:38184
name: picolinate
def: "A pyridinemonocarboxylate resulting from the removal of a proton from the carboxy group of picolinic acid." []
is_a: CHEBI:38181 ! pyridinemonocarboxylate
relationship: RO:0018033 CHEBI:28747 ! is deprotonated form of picolinic acid

[Term]
id: CHEBI:38186
name: isonicotinate
def: "A pyridinemonocarboxylate resulting from the deprotonation of the carboxy group of isonicotinic acid." []
is_a: CHEBI:38181 ! pyridinemonocarboxylate
relationship: RO:0018033 CHEBI:6032 ! is deprotonated form of isonicotinic acid

[Term]
id: CHEBI:38188
name: pyridinium salt
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:38193
name: phenylpyridine
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:38207
name: aminopyridine
def: "Compounds containing a pyridine skeleton substituted by one or more amine groups." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:33860 ! aromatic amine

[Term]
id: CHEBI:38210
name: aminonaphthalenesulfonic acid
def: "A naphthalenesulfonic acid having at least one amino substituent." []
is_a: CHEBI:36336 ! naphthalenesulfonic acid
is_a: CHEBI:37793 ! amino sulfonic acid
is_a: CHEBI:38034 ! aminonaphthalene

[Term]
id: CHEBI:38211
name: potassium bromate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22923 ! bromate salt
is_a: CHEBI:26218 ! potassium salt
relationship: RO:0000087 CHEBI:64577 ! has role flour treatment agent

[Term]
id: CHEBI:38214
name: monuron
def: "A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a <em>p</em>-chlorophenyl group while the other is substituted by two methyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:157693 ! 3-(3,4-substituted-phenyl)-1,1-dimethylurea
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:38215
name: calcium channel blocker
def: "One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools." []
is_a: CHEBI:38808 ! calcium channel modulator
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:38218
name: isophthalonitrile
is_a: CHEBI:18379 ! nitrile
relationship: RO:0018038 CHEBI:30802 ! has functional parent isophthalic acid

[Term]
id: CHEBI:38222
name: hydrocarbyl anion
is_a: CHEBI:25696 ! organic anion

[Term]
id: CHEBI:38231
name: phytotoxin
def: "Any toxin produced by a plant." []
is_a: CHEBI:27026 ! toxin
is_a: CHEBI:76924 ! plant metabolite

[Term]
id: CHEBI:38234
name: DNA polymerase inhibitor
def: "Any inhibitor of a DNA polymerase." []
is_a: CHEBI:76815 ! EC 2.7.7.* (nucleotidyltransferase) inhibitor

[Term]
id: CHEBI:38260
name: pyrrolidines
def: "Any of a class of heterocyclic amines having a saturated five-membered ring." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38261
name: imidazolidines
is_a: CHEBI:38304 ! diazolidine

[Term]
id: CHEBI:38263
name: 2-amino-3-hydroxybutanoic acid
def: "An α-amino acid that is butanoic acid substituted by an amino group at position 2 and a hydroxy group at position 3." []
is_a: CHEBI:33704 ! alpha-amino acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:38264
name: 2-amino-3-methylpentanoic acid
def: "A branched chain amino acid that consists of 3-methylpentanoic acid bearing an amino substituent at position 2." []
is_a: CHEBI:22918 ! branched-chain amino acid
is_a: CHEBI:33704 ! alpha-amino acid

[Term]
id: CHEBI:38267
name: boronic acid
def: "The simplest boronic acid, consisting of borane with two of the hydrogens substituted by hydroxy groups." []
is_a: CHEBI:38269 ! boronic acids

[Term]
id: CHEBI:38269
name: boronic acids
def: "Compounds having the structure RB(OH)<small><sub>2</sub></small>." []
is_a: CHEBI:33145 ! boron oxoacid

[Term]
id: CHEBI:38275
name: pyrrolidinone
is_a: CHEBI:38260 ! pyrrolidines

[Term]
id: CHEBI:38278
name: organoboron compound
def: "A compound containing at least one carbon-boron bond." []
is_a: CHEBI:22916 ! boron molecular entity
is_a: CHEBI:33285 ! heteroorganic entity

[Term]
id: CHEBI:38290
name: L-ascorbate
def: "The <small>L</small>-enantiomer of ascorbate and conjugate base of <small>L</small>-ascorbic acid, arising from selective deprotonation of the 3-hydroxy group. Required for a range of essential metabolic reactions in all animals and plants." []
is_a: CHEBI:176783 ! vitamin C
is_a: CHEBI:22651 ! ascorbate
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018033 CHEBI:29073 ! is deprotonated form of L-ascorbic acid

[Term]
id: CHEBI:38295
name: azabicycloalkane
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38297
name: thiabicycloalkane
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:38298
name: benzodioxoles
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:38303
name: azirinopyrroloindole
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38163 ! organic heterotetracyclic compound

[Term]
id: CHEBI:38304
name: diazolidine
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38305
name: gibberellin monocarboxylic acid
is_a: CHEBI:25384 ! monocarboxylic acid

[Term]
id: CHEBI:38307
name: imidazolyl carboxylic acid
def: "Any member of the class of imidazoles in which the imidazole ring is substituted by one (or more) carboxy group(s)." []
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:33859 ! aromatic carboxylic acid
relationship: RO:0018034 CHEBI:38466 ! is protonated form of imidazolyl carboxylic acid anion

[Term]
id: CHEBI:38311
name: cephem
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:27933 ! beta-lactam antibiotic
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:38313
name: diazines
def: "Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure)." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38314
name: pyrazines
is_a: CHEBI:38313 ! diazines

[Term]
id: CHEBI:38315
name: beta-D-arabinoside
is_a: CHEBI:22601 ! arabinoside

[Term]
id: CHEBI:38317
name: EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
def: "An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the activity of 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)." []
is_a: CHEBI:76837 ! EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor

[Term]
id: CHEBI:38321
name: mesotrione
def: "An aromatic ketone that is cyclohexa-1,3-dione in which one of the hydrogens at position 2 is substituted by a 4-(methanesulfonyl)-2-nitrobenzoyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140323 ! beta-triketone
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:35850 ! sulfone
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:138208 ! has role carotenoid biosynthesis inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38317 ! has role EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:41308 ! has functional parent benzophenone

[Term]
id: CHEBI:38323
name: cholinergic drug
def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:38324
name: cholinergic agonist
def: "Any drug that binds to and activates cholinergic receptors." []
is_a: CHEBI:38323 ! cholinergic drug

[Term]
id: CHEBI:38325
name: muscarinic agonist
def: "Any drug that binds to and activates a muscarinic cholinergic receptor." []
is_a: CHEBI:38324 ! cholinergic agonist

[Term]
id: CHEBI:38329
name: oxazolidines
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:38335
name: dithiolane
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:39192 ! dithiolanes

[Term]
id: CHEBI:38337
name: pyrimidone
def: "A pyrimidine carrying one or more oxo substituents." []
is_a: CHEBI:39447 ! pyrimidines

[Term]
id: CHEBI:38338
name: aminopyrimidine
def: "A member of the class of  pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives." []
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:39447 ! pyrimidines

[Term]
id: CHEBI:38340
name: hydroxypyrimidine
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:74818 ! heteroaryl hydroxy compound

[Term]
id: CHEBI:38355
name: hex-4-enoic acid
def: "A hexenoic acid with the double bond at position 4." []
is_a: CHEBI:24580 ! hexenoic acid

[Term]
id: CHEBI:38363
name: hept-6-enoic acid
def: "A heptenoic acid with the double bond at position 6." []
is_a: CHEBI:36151 ! heptenoic acid

[Term]
id: CHEBI:38387
name: 9,11,15-octadecatrienoic acid
def: "Any octadecatrienoic acid with three double bonds at positions 9, 11 and 15." []
is_a: CHEBI:25633 ! octadecatrienoic acid
relationship: RO:0018034 CHEBI:38390 ! is protonated form of 9,11,15-octadecatrienoate

[Term]
id: CHEBI:38390
name: 9,11,15-octadecatrienoate
def: "Any octadecatrienoate having double bonds at positions 9, 11 and 15." []
is_a: CHEBI:36434 ! octadecatrienoate
relationship: RO:0018033 CHEBI:38387 ! is deprotonated form of 9,11,15-octadecatrienoic acid

[Term]
id: CHEBI:38397
name: perfluorononanoic acid
def: "A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:35195 ! has role surfactant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0018038 CHEBI:29019 ! has functional parent nonanoic acid

[Term]
id: CHEBI:38418
name: 1,3-thiazoles
is_a: CHEBI:48901 ! thiazoles

[Term]
id: CHEBI:38419
name: saturated organic heterobicyclic parent
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:36388 ! saturated organic heterocyclic parent

[Term]
id: CHEBI:38443
name: 1-benzopyran
is_a: CHEBI:22727 ! benzopyran

[Term]
id: CHEBI:38444
name: 2-benzopyran
is_a: CHEBI:22727 ! benzopyran

[Term]
id: CHEBI:38445
name: chromenone
is_a: CHEBI:23232 ! chromenes

[Term]
id: CHEBI:38449
name: methoxyfenozide
def: "A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by 3-methoxy-2-methylbenzoyl, 3,5-dimethylbenzoyl,  and <em>tert</em>-butyl groups respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:35363 ! carbohydrazide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38457 ! has functional parent N'-benzoyl-N-(tert-butyl)benzohydrazide

[Term]
id: CHEBI:38452
name: tebufenozide
def: "A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by <em>tert</em>-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35363 ! carbohydrazide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38456 ! has role ecdysone agonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38457 ! has functional parent N'-benzoyl-N-(tert-butyl)benzohydrazide

[Term]
id: CHEBI:38453
name: 1,2-dibenzoylhydrazine
is_a: CHEBI:35363 ! carbohydrazide
relationship: RO:0018038 CHEBI:38454 ! has functional parent benzohydrazide

[Term]
id: CHEBI:38454
name: benzohydrazide
is_a: CHEBI:35363 ! carbohydrazide
relationship: RO:0018038 CHEBI:30746 ! has functional parent benzoic acid

[Term]
id: CHEBI:38455
name: bisacylhydrazine insecticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35363 ! carbohydrazide
relationship: RO:0000087 CHEBI:38456 ! has role ecdysone agonist

[Term]
id: CHEBI:38456
name: ecdysone agonist
is_a: CHEBI:24851 ! insect growth regulator

[Term]
id: CHEBI:38457
name: N'-benzoyl-N-(tert-butyl)benzohydrazide
is_a: CHEBI:38455 ! bisacylhydrazine insecticide
relationship: RO:0018038 CHEBI:38453 ! has functional parent 1,2-dibenzoylhydrazine

[Term]
id: CHEBI:38459
name: oxindoles
def: "Any member of the class of indolones whose structure is based on an oxindole (2-indolone) skeleton." []
is_a: CHEBI:24829 ! indolones
is_a: CHEBI:74222 ! gamma-lactam

[Term]
id: CHEBI:38460
name: methylindole
def: "Any member of the class of indoles carrying one or more methyl substituents." []
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:38461
name: carbamate insecticide
def: "Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR<small><sup>1</small></sup>R<small><sup>2</small></sup>, where ROH is an alcohol, oxime, or phenol and R<small><sup>1</small></sup> is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief." []
is_a: CHEBI:24852 ! insecticide
is_a: CHEBI:38462 ! EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:38462
name: EC 3.1.1.7 (acetylcholinesterase) inhibitor
def: "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid." []
is_a: CHEBI:76773 ! EC 3.1.1.* (carboxylic ester hydrolase) inhibitor

[Term]
id: CHEBI:38466
name: imidazolyl carboxylic acid anion
def: "A monocarboxylic acid anion resulting from the deprotonation of the carboxy group of an imidazolyl carboxylic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:38307 ! is deprotonated form of imidazolyl carboxylic acid

[Term]
id: CHEBI:38467
name: indolyl alcohol
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:38468
name: indol-3-yl carboxylic acid anion
is_a: CHEBI:35757 ! monocarboxylic acid anion

[Term]
id: CHEBI:38472
name: acetonitrile
def: "A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group." []
synonym: "ACETONITRILE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:80291 ! aliphatic nitrile
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:77941 ! has role EC 3.5.1.4 (amidase) inhibitor

[Term]
id: CHEBI:38481
name: alkaloid ester
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:33308 ! carboxylic ester

[Term]
id: CHEBI:38482
name: indole alkaloid fundamental parent
is_a: CHEBI:35506 ! alkaloid fundamental parent

[Term]
id: CHEBI:38494
name: benzoylurea insecticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134043 ! phenylureas
is_a: CHEBI:74266 ! N-acylurea
relationship: RO:0000087 CHEBI:39379 ! has role lepidopteran inhibitor of chitin biosynthesis
relationship: RO:0018038 CHEBI:39416 ! has functional parent N-benzoylurea

[Term]
id: CHEBI:38495
name: aluminium phosphide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35510 ! aluminium salt
relationship: RO:0000087 CHEBI:38500 ! has role EC 1.9.3.1 (cytochrome c oxidase) inhibitor

[Term]
id: CHEBI:38496
name: electron-transport chain inhibitor
is_a: CHEBI:76932 ! pathway inhibitor

[Term]
id: CHEBI:38497
name: respiratory-chain inhibitor
is_a: CHEBI:38496 ! electron-transport chain inhibitor

[Term]
id: CHEBI:38498
name: mitochondrial NADH:ubiquinone reductase inhibitor
is_a: CHEBI:25355 ! mitochondrial respiratory-chain inhibitor
is_a: CHEBI:38503 ! EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor

[Term]
id: CHEBI:38499
name: mitochondrial cytochrome-bc1 complex inhibitor
is_a: CHEBI:25355 ! mitochondrial respiratory-chain inhibitor
is_a: CHEBI:38502 ! cytochrome-bc1 complex inhibitor

[Term]
id: CHEBI:38500
name: EC 1.9.3.1 (cytochrome c oxidase) inhibitor
def: "An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome <em>c</em> oxidase (EC 1.9.3.1)." []
is_a: CHEBI:25355 ! mitochondrial respiratory-chain inhibitor
is_a: CHEBI:76870 ! EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor

[Term]
id: CHEBI:38502
name: cytochrome-bc1 complex inhibitor
is_a: CHEBI:38497 ! respiratory-chain inhibitor

[Term]
id: CHEBI:38503
name: EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor
def: "A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H<small><sup>+</small></sup>-translocating), EC 1.6.5.3." []
is_a: CHEBI:38497 ! respiratory-chain inhibitor
is_a: CHEBI:76866 ! EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor

[Term]
id: CHEBI:38508
name: methiocarb
def: "A carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfanyl)phenol with the carboxy group of  methylcarbamic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:86315 ! methyl sulfide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:33904 ! has role molluscicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38509 ! has functional parent 3,5-dimethyl-4-(methylsulfanyl)phenol
relationship: RO:0018038 CHEBI:45379 ! has functional parent methylcarbamic acid

[Term]
id: CHEBI:38509
name: 3,5-dimethyl-4-(methylsulfanyl)phenol
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35683 ! aryl sulfide

[Term]
id: CHEBI:38512
name: dibenzoquinolizine
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38514
name: quinoline alkaloid fundamental parent
is_a: CHEBI:35506 ! alkaloid fundamental parent

[Term]
id: CHEBI:38515
name: isoquinoline alkaloid fundamental parent
is_a: CHEBI:35506 ! alkaloid fundamental parent

[Term]
id: CHEBI:38523
name: benzazepine alkaloid
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:35676 ! benzazepine

[Term]
id: CHEBI:38527
name: benzazepine alkaloid fundamental parent
is_a: CHEBI:35506 ! alkaloid fundamental parent

[Term]
id: CHEBI:38530
name: quinazolines
def: "Any organic heterobicyclic compound based on a quinazoline skeleton and its substituted derivatives." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38532
name: hydrazone
def: "Compounds having the structure R<small><sub>2</sub></small>C=NNR<small><sub>2</sub></small>, formally derived from aldehydes or ketones by replacing =O by =NNH<small><sub>2</sub></small> (or substituted analogues)." []
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:38534
name: 1-(methylsulfanyl)acetaldoxime
is_a: CHEBI:86315 ! methyl sulfide
relationship: RO:0018038 CHEBI:51280 ! has functional parent S-methyl thioacetate

[Term]
id: CHEBI:38544
name: dimethylcarbamic acid
def: "An amino acid consisting of carbamic acid having two methyl substituents both attached to the nitrogen." []
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018038 CHEBI:28616 ! has functional parent carbamic acid

[Term]
id: CHEBI:38545
name: rosuvastatin
def: "A dihydroxy monocarboxylic acid that is (6<i>E</i>)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3<i>R</i>,5<i>S</i>-diastereomer)." []
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:35972 ! dihydroxy monocarboxylic acid
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:83575 ! monofluorobenzenes
is_a: CHEBI:87635 ! statin (synthetic)
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:49205 ! has role CETP inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77307 ! has role cardioprotective agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:77313 ! is protonated form of rosuvastatin(1-)
relationship: RO:0018038 CHEBI:38363 ! has functional parent hept-6-enoic acid

[Term]
id: CHEBI:38547
name: 2-isopropoxyphenol
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:38548
name: thiodicarb
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33904 ! has role molluscicide
relationship: RO:0000087 CHEBI:38461 ! has role carbamate insecticide
relationship: RO:0018038 CHEBI:6835 ! has functional parent methomyl

[Term]
id: CHEBI:38560
name: simple protein
is_a: CHEBI:36080 ! protein

[Term]
id: CHEBI:38570
name: 2,3,5-trimethylphenol
is_a: CHEBI:33853 ! phenols
relationship: RO:0018040 CHEBI:34039 ! has parent hydride 1,2,4-trimethylbenzene

[Term]
id: CHEBI:38580
name: oxazolo[4,5-b]pyridin-2(3H)-one
is_a: CHEBI:25000 ! lactone
relationship: RO:0018040 CHEBI:38581 ! has parent hydride oxazolo[4,5-b]pyridine

[Term]
id: CHEBI:38581
name: oxazolo[4,5-b]pyridine
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent
is_a: CHEBI:38765 ! oxazolopyridine

[Term]
id: CHEBI:38582
name: difluorobenzene
def: "Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying two fluorine atoms." []
is_a: CHEBI:35496 ! fluorobenzenes

[Term]
id: CHEBI:38584
name: 1,3-difluorobenzene
def: "A difluorobenzene carrying fluoro groups at positions 1 and 3." []
is_a: CHEBI:38582 ! difluorobenzene

[Term]
id: CHEBI:38586
name: 1,2,3-benzotriazine
is_a: CHEBI:39097 ! benzotriazine

[Term]
id: CHEBI:38595
name: 3H-pyrazole
is_a: CHEBI:14973 ! pyrazole
relationship: RO:0018036 CHEBI:17241 ! is tautomer of 1H-pyrazole
relationship: RO:0018036 CHEBI:38599 ! is tautomer of 4H-pyrazole

[Term]
id: CHEBI:38596
name: pyrazolide
def: "An organic anion with formula C<small><sub>3</sub></small>H<small><sub>3</sub></small>N<small><sub>2</sub></small> resulting from the removal of a proton from 1<em>H</em>, 3<em>H</em>, or 4<em>H</em>-pyrazole." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:14973 ! is deprotonated form of pyrazole

[Term]
id: CHEBI:38597
name: triazole
is_a: CHEBI:35555 ! mancude organic heteromonocyclic parent
is_a: CHEBI:35727 ! triazoles

[Term]
id: CHEBI:38599
name: 4H-pyrazole
is_a: CHEBI:14973 ! pyrazole
relationship: RO:0018034 CHEBI:38600 ! is protonated form of 4H-pyrazol-4-ide
relationship: RO:0018036 CHEBI:17241 ! is tautomer of 1H-pyrazole
relationship: RO:0018036 CHEBI:38595 ! is tautomer of 3H-pyrazole

[Term]
id: CHEBI:38600
name: 4H-pyrazol-4-ide
is_a: CHEBI:38596 ! pyrazolide
relationship: RO:0018033 CHEBI:38599 ! is deprotonated form of 4H-pyrazole

[Term]
id: CHEBI:38601
name: pyrazole pesticide
is_a: CHEBI:26410 ! pyrazoles

[Term]
id: CHEBI:38602
name: pyrazole acaricide
is_a: CHEBI:38601 ! pyrazole pesticide

[Term]
id: CHEBI:38605
name: phenethylamine alkaloid
is_a: CHEBI:22315 ! alkaloid

[Term]
id: CHEBI:38623
name: EC 1.4.3.4 (monoamine oxidase) inhibitor
def: "An EC 1.4.3.* (oxidoreductase acting on donor CH-NH<small><sub>2</sub></small> group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4)." []
is_a: CHEBI:76861 ! EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor

[Term]
id: CHEBI:38629
name: 2-isopropyl-6-methylpyrimidin-4-ol
def: "A hydroxypyrimidine that is pyrimidine substituted by an isopropyl group at position 2, a methyl group at position 6 and a hydroxy group at position 4." []
is_a: CHEBI:38340 ! hydroxypyrimidine
relationship: RO:0018036 CHEBI:83445 ! is tautomer of 2-isopropyl-6-methyl-4-pyrimidinone

[Term]
id: CHEBI:38631
name: aminoalkylindole
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:38632
name: membrane transport modulator
def: "Any agent that affects the transport of molecular entities across a biological membrane." []
is_a: CHEBI:52208 ! biophysical role

[Term]
id: CHEBI:38633
name: sodium channel blocker
def: "An agent that inhibits sodium influx through cell membranes." []
is_a: CHEBI:39000 ! sodium channel modulator

[Term]
id: CHEBI:38634
name: voltage-gated sodium channel blocker
def: "Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels." []
is_a: CHEBI:38633 ! sodium channel blocker

[Term]
id: CHEBI:38635
name: 3-methyladenine
def: "A  methyladenine that is adenine substituted with a methyl group at position N-3." []
synonym: "3-Methyladenine" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25272 ! methyladenine
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:88230 ! has role autophagy inhibitor

[Term]
id: CHEBI:38637
name: tyrosine kinase inhibitor
def: "Any protein kinase inhibitor that interferes with the action of tyrosine kinase." []
is_a: CHEBI:37699 ! protein kinase inhibitor

[Term]
id: CHEBI:38641
name: trimethylbenzene
is_a: CHEBI:38975 ! methylbenzene

[Term]
id: CHEBI:38643
name: 6-isopentenylaminopurine
is_a: CHEBI:22527 ! aminopurine
relationship: RO:0018038 CHEBI:16708 ! has functional parent adenine

[Term]
id: CHEBI:38645
name: N-glycosylzeatin
is_a: CHEBI:21731 ! N-glycosyl compound
relationship: RO:0018038 CHEBI:15333 ! has functional parent zeatin

[Term]
id: CHEBI:38653
name: methylbutyric acid
def: "A methyl-branched fatty acid comprising a butyric acid core carrying a single methyl substituent." []
is_a: CHEBI:26666 ! short-chain fatty acid
is_a: CHEBI:39417 ! branched-chain saturated fatty acid
is_a: CHEBI:62499 ! methyl-branched fatty acid
relationship: RO:0018038 CHEBI:30772 ! has functional parent butyric acid

[Term]
id: CHEBI:38655
name: (S)-2-methylbutyric acid
def: "The (<i>S</i>)-enantiomer of 2-methylbutanoic acid." []
is_a: CHEBI:37070 ! 2-methylbutyric acid
relationship: RO:0018034 CHEBI:145932 ! is protonated form of (S)-2-methylbutanoate
relationship: RO:0018039 CHEBI:45525 ! is enantiomer of (R)-2-methylbutyric acid

[Term]
id: CHEBI:38656
name: organochlorine pesticide
def: "Any organochlorine compound that has been used as a pesticide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:25944 ! has role pesticide

[Term]
id: CHEBI:38657
name: organochlorine acaricide
def: "Any organochlorine pesticide that has been used as an acaricide." []
is_a: CHEBI:38656 ! organochlorine pesticide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide

[Term]
id: CHEBI:38658
name: dicrotophos
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:25708 ! organophosphate insecticide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:38661
name: disulfoton
def: "An organic thiophosphate that is the diethyl ester of <i>S</i>-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate." []
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:38663
name: ethion
def: "An organic thiophosphate that is S,S'-methanediyl bis[dihydrogen (phosphorodithioate)] in which all the hydroxy groups have been converted to their corresponding ethyl esters respectively. Ethion is an organophosphate insecticide with inhibitory activity towards the enzyme acetylcholinesterase ( EC 3.1.1.7)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:38665
name: ethoprophos
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:38669
name: pyrazolopyrimidine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38670
name: pyrrolopyrimidine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38672
name: flavans
def: "Any flavonoid with a 3,4-dihydro-2-aryl-2<em>H</em>-1-benzopyran skeleton and its substituted derivatives." []
is_a: CHEBI:26004 ! phenylpropanoid
is_a: CHEBI:38443 ! 1-benzopyran
is_a: CHEBI:47916 ! flavonoid

[Term]
id: CHEBI:38677
name: famphur
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35443 ! has role anthelminthic drug
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38678 ! has functional parent 4-hydroxy-N,N-dimethylbenzenesulfonamide

[Term]
id: CHEBI:38678
name: 4-hydroxy-N,N-dimethylbenzenesulfonamide
is_a: CHEBI:35358 ! sulfonamide
relationship: RO:0018038 CHEBI:32354 ! has functional parent 4-hydroxybenzenesulfonic acid

[Term]
id: CHEBI:38680
name: fenamiphos
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:27577 ! phosphoramidate ester
is_a: CHEBI:39094 ! organophosphate nematicide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38681 ! has functional parent 4-(methylsulfanyl)-m-cresol

[Term]
id: CHEBI:38681
name: 4-(methylsulfanyl)-m-cresol
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35683 ! aryl sulfide
relationship: RO:0018038 CHEBI:17231 ! has functional parent m-cresol

[Term]
id: CHEBI:38682
name: bromoform
synonym: "Bromoform" EXACT [KEGG_COMPOUND]
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:39278 ! bromomethanes

[Term]
id: CHEBI:38684
name: tetrahydroxyflavone
def: "Any hydroxyflavone carrying four hydroxy substituents." []
is_a: CHEBI:24698 ! hydroxyflavone

[Term]
id: CHEBI:38685
name: 1,2-epoxypropane
def: "An epoxide that is oxirane substituted by a methyl group at position 2." []
is_a: CHEBI:32955 ! epoxide
relationship: RO:0018038 CHEBI:27561 ! has functional parent oxirane

[Term]
id: CHEBI:38686
name: dihydroxyflavone
def: "Any hydroxyflavone in which two ring hydrogens are replaced by hydroxy substituents." []
is_a: CHEBI:24698 ! hydroxyflavone

[Term]
id: CHEBI:38688
name: 4-(methylsulfinyl)phenol
is_a: CHEBI:22063 ! sulfoxide
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:38689
name: fonofos
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:38697
name: anthocyanin
def: "Any flavonoid that is a glycoside derivative of anthocyanidin. Anthocyanins are water-souluble plant pigments that generally occur as acidic salts exhibiting bright colours." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:47916 ! flavonoid
relationship: BFO:0000051 CHEBI:35218 ! has part anthocyanin cation

[Term]
id: CHEBI:38699
name: sodium fluoroacetate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:18172 ! has part fluoroacetate
relationship: RO:0000087 CHEBI:33288 ! has role rodenticide

[Term]
id: CHEBI:38700
name: organic sodium salt
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:26714 ! sodium salt

[Term]
id: CHEBI:38702
name: inorganic sodium salt
is_a: CHEBI:24839 ! inorganic salt
is_a: CHEBI:26714 ! sodium salt

[Term]
id: CHEBI:38705
name: thiomalic acid
is_a: CHEBI:66873 ! C4-dicarboxylic acid
relationship: RO:0018034 CHEBI:38708 ! is protonated form of thiomalate(1-)
relationship: RO:0018038 CHEBI:15741 ! has functional parent succinic acid

[Term]
id: CHEBI:38706
name: pediculicide
def: "Substance used to treat lice (genus <em>Pediculus</em>) infestation." []
is_a: CHEBI:24852 ! insecticide

[Term]
id: CHEBI:38708
name: thiomalate(1-)
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:38705 ! is deprotonated form of thiomalic acid
relationship: RO:0018034 CHEBI:38710 ! is protonated form of thiomalate(2-)

[Term]
id: CHEBI:38710
name: thiomalate(2-)
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0018033 CHEBI:38708 ! is deprotonated form of thiomalate(1-)
relationship: RO:0018034 CHEBI:38715 ! is protonated form of thiomalate(3-)

[Term]
id: CHEBI:38715
name: thiomalate(3-)
is_a: CHEBI:38717 ! carboxylic acid trianion
relationship: RO:0018033 CHEBI:38710 ! is deprotonated form of thiomalate(2-)
relationship: RO:0018038 CHEBI:30031 ! has functional parent succinate(2-)

[Term]
id: CHEBI:38716
name: carboxylic acid dianion
def: "Any dianion containing at least one carboxy group." []
is_a: CHEBI:29067 ! carboxylic acid anion

[Term]
id: CHEBI:38717
name: carboxylic acid trianion
def: "A trianion containing at least one carboxy group." []
is_a: CHEBI:29067 ! carboxylic acid anion

[Term]
id: CHEBI:38721
name: methamidophos
def: "An organic thiophosphate resulting from the <em>N</em>-deacylation of the proinsecticide acephate." []
is_a: CHEBI:17102 ! phosphoramide
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide

[Term]
id: CHEBI:38725
name: mevinphos
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:25708 ! organophosphate insecticide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38726 ! has functional parent methyl 3-hydroxybut-2-enoate

[Term]
id: CHEBI:38726
name: methyl 3-hydroxybut-2-enoate
is_a: CHEBI:4986 ! fatty acid methyl ester
relationship: RO:0018038 CHEBI:17217 ! has functional parent 2-butenoic acid

[Term]
id: CHEBI:38728
name: monocrotophos
def: "An alkenyl phosphate that is the 4-(methylamino)-4-oxobut-2-en-2-yl ester of dimethyl phosphate." []
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:37494 ! alkenyl phosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33289 ! has role avicide
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38623 ! has role EC 1.4.3.4 (monoamine oxidase) inhibitor

[Term]
id: CHEBI:38729
name: naled
def: "An dialkyl phosphate resulting from the formal condensation of the acidic hydroxy group of dimethyl hydrogen phosphate with the alcoholic hydroxy group of 1,2-dibromo-2,2-dichloroethanol. An organophosphate insecticide, it is no longer approved for use within the European Union." []
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37141 ! organobromine compound
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:38731
name: N-methyl-2-sulfanylacetamide
def: "A monocarboxylic acid amide resulting from formal condensation between mercaptoacetic acid and methylamine." []
is_a: CHEBI:29347 ! monocarboxylic acid amide
relationship: RO:0018038 CHEBI:27856 ! has functional parent acetamide

[Term]
id: CHEBI:38735
name: oxydemeton-methyl
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38736 ! has functional parent 2-(ethanesulfinyl)ethanol

[Term]
id: CHEBI:38736
name: 2-(ethanesulfinyl)ethanol
is_a: CHEBI:22063 ! sulfoxide

[Term]
id: CHEBI:38737
name: tribufos
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:23582 ! has role defoliant

[Term]
id: CHEBI:38738
name: monomethoxyflavanone
def: "Any methoxyflavanone that is flavanone substituted by a methoxy group." []
is_a: CHEBI:25240 ! methoxyflavanone

[Term]
id: CHEBI:38739
name: trihydroxyflavanone
def: "A hydroxyflavanone carrying three hydroxy substituents." []
is_a: CHEBI:24697 ! hydroxyflavanone

[Term]
id: CHEBI:38742
name: tetrahydroxyflavanone
def: "A hydroxyflavanone with at least four hydroxy substituents." []
is_a: CHEBI:24697 ! hydroxyflavanone

[Term]
id: CHEBI:38746
name: parathion-methyl
def: "A <em>C</em>-nitro compound that is  4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4." []
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:16836 ! has functional parent 4-nitrophenol

[Term]
id: CHEBI:38749
name: dihydroxyflavanone
def: "Any  hydroxyflavanone carrying two hydroxy substituents." []
is_a: CHEBI:24697 ! hydroxyflavanone

[Term]
id: CHEBI:38751
name: triamine
def: "Any polyamine that contained three amino groups." []
is_a: CHEBI:88061 ! polyamine

[Term]
id: CHEBI:38755
name: hydroxyisoflavone
def: "Member of the class of isoflavones bearing at least one hydroxy group." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:38757 ! isoflavones

[Term]
id: CHEBI:38756
name: methoxyisoflavone
def: "Members of the class of isoflavones with at least one methoxy substituent." []
is_a: CHEBI:25698 ! ether
is_a: CHEBI:38757 ! isoflavones

[Term]
id: CHEBI:38757
name: isoflavones
def: "Any isoflavonoid with a 3-aryl-1-benzopyran-4-one (3-aryl-4<em>H</em>-chromen-4-one) skeleton and its substituted derivatives." []
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:50753 ! isoflavonoid

[Term]
id: CHEBI:38758
name: isocoumarins
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:38761 ! isochromenes

[Term]
id: CHEBI:38761
name: isochromenes
is_a: CHEBI:38444 ! 2-benzopyran

[Term]
id: CHEBI:38762
name: isochromanes
is_a: CHEBI:38444 ! 2-benzopyran

[Term]
id: CHEBI:38764
name: phorate
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38829 ! has functional parent (ethylsulfanyl)methanethiol

[Term]
id: CHEBI:38765
name: oxazolopyridine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:38767
name: benzothiophenes
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:38768
name: phthalazines
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38769
name: indazoles
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38771
name: quinoxaline derivative
def: "Any naphthyridine derivative that is a derivative of quinoxaline (1,4-naphthyridine)." []
is_a: CHEBI:73539 ! naphthyridine derivative
relationship: RO:0018040 CHEBI:36616 ! has parent hydride quinoxaline

[Term]
id: CHEBI:38773
name: quinolinemonocarboxylate
def: "A monocarboxylic acid anion that is the monoanion obtained by the deprotonation of the carboxy group attached to the quinoline skeleton" []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:26512 ! is deprotonated form of quinolinemonocarboxylic acid

[Term]
id: CHEBI:38776
name: imidazoquinoline
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38777
name: azetidines
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38778
name: triazinanes
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38779
name: 1,3,5-triazinanes
is_a: CHEBI:38778 ! triazinanes

[Term]
id: CHEBI:38780
name: N-nitro compound
def: "A compound having the nitro group (‒NO<small><sub>2</sub></small>) attached to a nitrogen atom." []
is_a: CHEBI:35715 ! nitro compound

[Term]
id: CHEBI:38781
name: thiadiazinane
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:38784
name: oxetanes
def: "Any oxacycle that is oxetane or its substituted derivatives." []
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:38785
name: morpholines
def: "Any compound containing morpholine as part of its structure." []
is_a: CHEBI:46952 ! oxazinane

[Term]
id: CHEBI:38786
name: phosmet
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:82851 ! phthalimides
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38816 ! has functional parent N-(hydroxymethyl)phthalimide

[Term]
id: CHEBI:38791
name: azocanes
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38792
name: azocane
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:37949 ! azacycloalkane
is_a: CHEBI:38791 ! azocanes

[Term]
id: CHEBI:38793
name: pteroate
is_a: CHEBI:38796 ! pteroates
relationship: RO:0018033 CHEBI:38794 ! is deprotonated form of pteroic acid

[Term]
id: CHEBI:38794
name: pteroic acid
is_a: CHEBI:38795 ! pteroic acids
relationship: RO:0018034 CHEBI:38793 ! is protonated form of pteroate

[Term]
id: CHEBI:38795
name: pteroic acids
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:26375 ! pterins

[Term]
id: CHEBI:38796
name: pteroates
is_a: CHEBI:22494 ! aminobenzoate

[Term]
id: CHEBI:38800
name: benzenedicarboxamide
is_a: CHEBI:35779 ! dicarboxylic acid diamide

[Term]
id: CHEBI:38801
name: isophthalamide
is_a: CHEBI:38800 ! benzenedicarboxamide
relationship: RO:0018038 CHEBI:30802 ! has functional parent isophthalic acid

[Term]
id: CHEBI:38804
name: organofluorine insecticide
is_a: CHEBI:38805 ! organofluorine pesticide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide

[Term]
id: CHEBI:38805
name: organofluorine pesticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:25944 ! has role pesticide

[Term]
id: CHEBI:38806
name: organofluorine acaricide
is_a: CHEBI:38805 ! organofluorine pesticide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide

[Term]
id: CHEBI:38807
name: calcium channel agonist
def: "Agents that increase calcium influx into calcium channels of excitable tissues." []
is_a: CHEBI:38808 ! calcium channel modulator

[Term]
id: CHEBI:38808
name: calcium channel modulator
def: "A membrane transport modulator that is able to regulate intracellular calcium levels." []
is_a: CHEBI:38632 ! membrane transport modulator

[Term]
id: CHEBI:38809
name: ryanodine receptor modulator
is_a: CHEBI:38808 ! calcium channel modulator

[Term]
id: CHEBI:38816
name: N-(hydroxymethyl)phthalimide
def: "A primary alcohol comprising phthalimide carrying an <em>N</em>-hydroxymethyl substituent." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:82851 ! phthalimides
relationship: RO:0018038 CHEBI:38817 ! has functional parent phthalimide

[Term]
id: CHEBI:38817
name: phthalimide
def: "A  dicarboximide that is 2,3-dihydro-1<em>H</em>-isoindole substituted by oxo groups at positions 1 and 3." []
is_a: CHEBI:82851 ! phthalimides

[Term]
id: CHEBI:38819
name: quinoxaline antifungal agent
def: "A compound that has significant antifungal properties whose structure contains a quinoxaline moiety." []
is_a: CHEBI:38821 ! quinoxaline pesticide

[Term]
id: CHEBI:38820
name: quinoxaline acaricide
is_a: CHEBI:38821 ! quinoxaline pesticide
is_a: CHEBI:39366 ! organonitrogen acaricide

[Term]
id: CHEBI:38821
name: quinoxaline pesticide
def: "A quinoxaline derivative that has pesticidal properties." []
is_a: CHEBI:38771 ! quinoxaline derivative
is_a: CHEBI:39365 ! organonitrogen pesticide

[Term]
id: CHEBI:38823
name: diazepane
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38824
name: fluorocarbon
def: "Compounds consisting wholly of fluorine and carbon." []
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:38825
name: tetrafluoromethane
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38824 ! fluorocarbon
is_a: CHEBI:39281 ! fluoromethanes
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:38826
name: perfluorooctane
is_a: CHEBI:24067 ! fluoroalkane
is_a: CHEBI:38824 ! fluorocarbon
relationship: RO:0018040 CHEBI:17590 ! has parent hydride octane

[Term]
id: CHEBI:38828
name: nonionic surfactant
def: "A surfactant with an uncharged hydrophilic headgroup." []
is_a: CHEBI:35195 ! surfactant

[Term]
id: CHEBI:38829
name: (ethylsulfanyl)methanethiol
is_a: CHEBI:22327 ! aliphatic sulfide
is_a: CHEBI:47908 ! alkanethiol

[Term]
id: CHEBI:38830
name: 1-benzofurans
def: "A member of the class of benzofurans consisting of a 1-benzofuran skeleton and its substituted derivatives thereof." []
is_a: CHEBI:35259 ! benzofurans

[Term]
id: CHEBI:38831
name: 2-benzofurans
is_a: CHEBI:35259 ! benzofurans

[Term]
id: CHEBI:38835
name: xanthenes
is_a: CHEBI:39203 ! dibenzopyran

[Term]
id: CHEBI:38836
name: 1-benzothiophenes
is_a: CHEBI:38767 ! benzothiophenes

[Term]
id: CHEBI:38843
name: pirimiphos-methyl
def: "An  organic thiophosphate that is <em>O</em>,<em>O</em>-dimethyl <em>O</em>-pyrimidin-4-yl phosphorothioate substituted by a methyl group at position 6 and a diethylamino group at position 2." []
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:38338 ! aminopyrimidine
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38844 ! has functional parent 2-diethylamino-6-methylpyrimidin-4(1H)-one

[Term]
id: CHEBI:38844
name: 2-diethylamino-6-methylpyrimidin-4(1H)-one
is_a: CHEBI:38337 ! pyrimidone
is_a: CHEBI:38338 ! aminopyrimidine

[Term]
id: CHEBI:38845
name: profenofos
is_a: CHEBI:25705 ! organochlorine insecticide
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38852 ! has functional parent 4-bromo-2-chlorophenol

[Term]
id: CHEBI:38846
name: phenoxyacetate
def: "A monocarboxylic acid anion that is the conjugate base of phenoxyacetic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:8075 ! is deprotonated form of phenoxyacetic acid

[Term]
id: CHEBI:38847
name: perfluoroheptane
is_a: CHEBI:38824 ! fluorocarbon
relationship: RO:0018040 CHEBI:43098 ! has parent hydride heptane

[Term]
id: CHEBI:38852
name: 4-bromo-2-chlorophenol
def: "A halophenol that is phenol in which the hydrogens at positions 2 and 4 have been replaced by chlorine and bromine, respectively." []
is_a: CHEBI:37141 ! organobromine compound
is_a: CHEBI:38856 ! halophenol
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:38853
name: decalin
def: "An <em>ortho</em>-fused bicyclic hydrocarbon that is the decahydro- derivative of naphthalene." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35428 ! ortho-fused bicyclic hydrocarbon
relationship: RO:0000087 CHEBI:46787 ! has role solvent

[Term]
id: CHEBI:38856
name: halophenol
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:38857
name: monochlorophenol
is_a: CHEBI:23150 ! chlorophenol
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:38862
name: 4-(methylsulfanyl)phenol
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35683 ! aryl sulfide

[Term]
id: CHEBI:38864
name: propetamphos
is_a: CHEBI:25708 ! organophosphate insecticide
is_a: CHEBI:27577 ! phosphoramidate ester
is_a: CHEBI:35725 ! isopropyl ester
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38868 ! has functional parent isopropyl 3-hydroxybut-2-enoate

[Term]
id: CHEBI:38866
name: tetrafluoroethene
is_a: CHEBI:38824 ! fluorocarbon

[Term]
id: CHEBI:38867
name: anaesthetic
def: "Substance which produces loss of feeling or sensation." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:38868
name: isopropyl 3-hydroxybut-2-enoate
def: "An isopropyl ester resulting from the formal condensation of the carboxy group of 3-hydroxybut-2-enoic acid with isopropanol." []
is_a: CHEBI:35725 ! isopropyl ester
relationship: RO:0018038 CHEBI:38871 ! has functional parent 3-hydroxybut-2-enoic acid

[Term]
id: CHEBI:38869
name: general anaesthetic
def: "Substance that produces loss of consciousness." []
is_a: CHEBI:38867 ! anaesthetic

[Term]
id: CHEBI:38870
name: inhalation anaesthetic
is_a: CHEBI:38869 ! general anaesthetic

[Term]
id: CHEBI:38871
name: 3-hydroxybut-2-enoic acid
is_a: CHEBI:35969 ! 3-hydroxy monocarboxylic acid
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid

[Term]
id: CHEBI:38877
name: intravenous anaesthetic
is_a: CHEBI:38869 ! general anaesthetic

[Term]
id: CHEBI:38879
name: 1-phenylpyrazole
def: "A member of the class of pyrazoles that is 1<em>H</em>-pyrazole substituted by a phenyl group at position 1." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:26410 ! pyrazoles
relationship: RO:0018040 CHEBI:17241 ! has parent hydride 1H-pyrazole

[Term]
id: CHEBI:38884
name: diphenylmethane
def: "A diarylmethane that is methane substituted by two phenyl groups." []
is_a: CHEBI:51614 ! diarylmethane

[Term]
id: CHEBI:38893
name: 2,3,5-trimethylphenyl methylcarbamate
def: "A carbamate ester that consists of 2,3,5-trimethylphenol carrying an <em>O</em>-(<em>N</em>-methylcarbamoyl) group. One of two constituents of trimethacarb." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0018038 CHEBI:38570 ! has functional parent 2,3,5-trimethylphenol

[Term]
id: CHEBI:38900
name: boron halide
is_a: CHEBI:22916 ! boron molecular entity

[Term]
id: CHEBI:38901
name: boron fluoride
is_a: CHEBI:38900 ! boron halide

[Term]
id: CHEBI:38919
name: dithioloquinoxaline
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:3892
name: corticotropin
def: "A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The <em>N</em>-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency." []
is_a: CHEBI:15841 ! polypeptide
is_a: CHEBI:25905 ! peptide hormone
is_a: CHEBI:33694 ! biomacromolecule
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33295 ! has role diagnostic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent

[Term]
id: CHEBI:38920
name: benzochromene
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:38921
name: pyridoquinoline
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38922
name: dibenzofurans
def: "Any organic heterotricyclic compound based on a dibenzofuran skeleton and its substituted derivatives thereof." []
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:38925
name: benzopteridine
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:38929
name: 2-methoxy-1,3,5-triazine
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine

[Term]
id: CHEBI:38930
name: 6-methoxy-1,3,5-triazine-2,4-diamine
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
relationship: RO:0018038 CHEBI:38929 ! has functional parent 2-methoxy-1,3,5-triazine

[Term]
id: CHEBI:38932
name: pyridopyrimidine
def: "Any organic heterobicyclic compound consisting of a pyridine ring <em>ortho</em>-fused at any position to a pyrimidine ring." []
is_a: CHEBI:27171 ! organic heterobicyclic compound

[Term]
id: CHEBI:38934
name: purvalanol
is_a: CHEBI:38001 ! 2,6-diaminopurines

[Term]
id: CHEBI:38940
name: sunitinib
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24828 ! indoles
is_a: CHEBI:26455 ! pyrroles
is_a: CHEBI:29347 ! monocarboxylic acid amide
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:62434 ! has role EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:65207 ! has role vascular endothelial growth factor receptor antagonist
relationship: RO:0018038 CHEBI:17920 ! has functional parent 3-methyleneoxindole

[Term]
id: CHEBI:38941
name: schistosomicide drug
def: "Drugs that used to treat infestations by flukes (trematodes) of the genus <em>Schistosoma</em>." []
is_a: CHEBI:35684 ! antiplatyhelmintic drug

[Term]
id: CHEBI:38945
name: sulfotep
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38947 ! has functional parent dithiodiphosphoric acid

[Term]
id: CHEBI:38947
name: dithiodiphosphoric acid
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26079 ! phosphoric acid derivative
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent

[Term]
id: CHEBI:38949
name: sulprofos
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0018038 CHEBI:38862 ! has functional parent 4-(methylsulfanyl)phenol

[Term]
id: CHEBI:38954
name: temephos
def: "An organic sulfide that is diphenyl sulfide in which the hydrogen at the <em>para</em> position of each of the phenyl groups has been replaced by a (dimethoxyphosphorothioyl)oxy group." []
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:37512 ! organic thiophosphate
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38956 ! has role ectoparasiticide
relationship: RO:0018038 CHEBI:38957 ! has functional parent 4,4'-thiodiphenol

[Term]
id: CHEBI:38956
name: ectoparasiticide
is_a: CHEBI:35442 ! antiparasitic agent

[Term]
id: CHEBI:38957
name: 4,4'-thiodiphenol
is_a: CHEBI:33853 ! phenols
relationship: RO:0018040 CHEBI:38959 ! has parent hydride diphenyl sulfide

[Term]
id: CHEBI:38958
name: indole alkaloid
def: "An alkaloid containing an indole skeleton." []
is_a: CHEBI:22315 ! alkaloid
relationship: BFO:0000051 CHEBI:73398 ! has part indole skeleton

[Term]
id: CHEBI:38959
name: diphenyl sulfide
def: "An  aryl sulfide that consists of two phenyl groups connected by a sulphur atom." []
is_a: CHEBI:35683 ! aryl sulfide

[Term]
id: CHEBI:38961
name: 1-phenylethenol
is_a: CHEBI:33823 ! enol
relationship: RO:0018040 CHEBI:27452 ! has parent hydride styrene

[Term]
id: CHEBI:38967
name: 1-phenyl-1H-1,2,4-triazole
is_a: CHEBI:35727 ! triazoles

[Term]
id: CHEBI:38975
name: methylbenzene
def: "Any alkylbenzene that is benzene substituted with one or more methyl groups." []
is_a: CHEBI:38976 ! alkylbenzene

[Term]
id: CHEBI:38976
name: alkylbenzene
def: "A  monocyclic arene that is benzene substituted with one or more alkyl groups." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:33847 ! monocyclic arene
relationship: RO:0018040 CHEBI:16716 ! has parent hydride benzene

[Term]
id: CHEBI:38999
name: GABA-gated chloride channel antagonist
is_a: CHEBI:38632 ! membrane transport modulator
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:39000
name: sodium channel modulator
is_a: CHEBI:38632 ! membrane transport modulator

[Term]
id: CHEBI:39015
name: apolipoprotein
def: "Protein component on the surface of lipoprotein." []
is_a: CHEBI:13850 ! apoprotein

[Term]
id: CHEBI:39022
name: inclusion compound
def: "A complex in which one component (the host) forms a cavity or, in the case of a crystal, a crystal lattice containing spaces in the shape of long tunnels or channels in which molecular entities of a second chemical species (the guest) are located. There is no covalent bonding between guest and host, the attraction being generally due to van der Waals forces." []
is_a: CHEBI:50967 ! non-covalently-bound molecular entity

[Term]
id: CHEBI:39024
name: clathrate compound
def: "Inclusion compound in which the guest molecule is in a cage formed by the host molecule or by a lattice of host molecules." []
is_a: CHEBI:39022 ! inclusion compound

[Term]
id: CHEBI:39025
name: high-density lipoprotein
def: "A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. They are synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport)." []
is_a: CHEBI:6495 ! lipoprotein
relationship: BFO:0000051 CHEBI:47775 ! has part high-density lipoprotein cholesterol

[Term]
id: CHEBI:39026
name: low-density lipoprotein
def: "A class of lipoproteins of small size (18-25 nm) and low density (1.019-1.063 g/ml) particles with a core composed mainly of cholesterol esters and smaller amounts of triglycerides. The surface monolayer consists mostly of phospholipids, a single copy of apolipoprotein B-100, and free cholesterol molecules. The main function of LDL is to transport cholesterol and cholesterol esters from the liver. Excessive levels are associated with cardiovascular disease." []
is_a: CHEBI:6495 ! lipoprotein
relationship: BFO:0000051 CHEBI:47774 ! has part low-density lipoprotein cholesterol

[Term]
id: CHEBI:39053
name: nitrilotriacetate(1-)
is_a: CHEBI:36299 ! tricarboxylic acid monoanion
is_a: CHEBI:39054 ! NTA
relationship: RO:0018033 CHEBI:44557 ! is deprotonated form of nitrilotriacetic acid
relationship: RO:0018034 CHEBI:39056 ! is protonated form of nitrilotriacetate(2-)

[Term]
id: CHEBI:39054
name: NTA
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:38161 ! has role chelator
relationship: RO:0018038 CHEBI:35026 ! has functional parent triethylamine

[Term]
id: CHEBI:39056
name: nitrilotriacetate(2-)
is_a: CHEBI:36300 ! tricarboxylic acid dianion
is_a: CHEBI:39054 ! NTA
relationship: RO:0018033 CHEBI:39053 ! is deprotonated form of nitrilotriacetate(1-)
relationship: RO:0018034 CHEBI:25548 ! is protonated form of nitrilotriacetate(3-)

[Term]
id: CHEBI:39068
name: cis-chlordane
is_a: CHEBI:34623 ! chlordane

[Term]
id: CHEBI:39069
name: trans-chlordane
is_a: CHEBI:34623 ! chlordane

[Term]
id: CHEBI:39087
name: sulfurous acid derivative
def: "Any sulfur oxoacid derivative derived from sulfurous acid." []
is_a: CHEBI:33424 ! sulfur oxoacid derivative

[Term]
id: CHEBI:39088
name: sulfite ester
is_a: CHEBI:26823 ! sulfites
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:39089
name: cyclic sulfite ester
is_a: CHEBI:39088 ! sulfite ester

[Term]
id: CHEBI:39090
name: phenylpyrazole insecticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26410 ! pyrazoles
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0018038 CHEBI:38879 ! has functional parent 1-phenylpyrazole

[Term]
id: CHEBI:39092
name: organophosphorus nematicide
is_a: CHEBI:39093 ! organophosphorus pesticide
relationship: RO:0000087 CHEBI:25491 ! has role nematicide

[Term]
id: CHEBI:39093
name: organophosphorus pesticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25710 ! organophosphorus compound
relationship: RO:0000087 CHEBI:25944 ! has role pesticide

[Term]
id: CHEBI:39094
name: organophosphate nematicide
is_a: CHEBI:39092 ! organophosphorus nematicide

[Term]
id: CHEBI:39096
name: alpha-hexachlorocyclohexane
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24536 ! hexachlorocyclohexane
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:39097
name: benzotriazine
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent
is_a: CHEBI:38180 ! polycyclic heteroarene
is_a: CHEBI:50893 ! azaarene
is_a: CHEBI:51361 ! benzotriazines

[Term]
id: CHEBI:39100
name: (+)-trans-chrysanthemic acid
def: "A <i>trans</i>-chrysanthemic acid in which both stereocentres have <i>R</i> configuration." []
is_a: CHEBI:39101 ! trans-chrysanthemic acid
relationship: RO:0018034 CHEBI:143900 ! is protonated form of (R,R)-chrysanthemate
relationship: RO:0018038 CHEBI:143899 ! has functional parent (R,R)-chrysanthemal
relationship: RO:0018039 CHEBI:39102 ! is enantiomer of (-)-trans-chrysanthemic acid

[Term]
id: CHEBI:39101
name: trans-chrysanthemic acid
is_a: CHEBI:3680 ! chrysanthemic acid

[Term]
id: CHEBI:39102
name: (-)-trans-chrysanthemic acid
is_a: CHEBI:39101 ! trans-chrysanthemic acid
relationship: RO:0018039 CHEBI:39100 ! is enantiomer of (+)-trans-chrysanthemic acid

[Term]
id: CHEBI:39103
name: cis-chrysanthemic acid
is_a: CHEBI:3680 ! chrysanthemic acid

[Term]
id: CHEBI:39106
name: pyrene
def: "An <em>ortho</em>- and <em>peri</em>-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system." []
synonym: "Pyrene" EXACT [KEGG_COMPOUND]
is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene
relationship: RO:0000087 CHEBI:39442 ! has role fluorescent probe
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:39116
name: pyrethroid ester insecticide
is_a: CHEBI:26413 ! pyrethroid insecticide

[Term]
id: CHEBI:39117
name: trans-allethrin
is_a: CHEBI:34572 ! allethrin
relationship: RO:0018038 CHEBI:39101 ! has functional parent trans-chrysanthemic acid

[Term]
id: CHEBI:39118
name: (+)-trans-allethrin
is_a: CHEBI:39117 ! trans-allethrin
relationship: RO:0018038 CHEBI:39100 ! has functional parent (+)-trans-chrysanthemic acid

[Term]
id: CHEBI:39123
name: calcium cation
is_a: CHEBI:33513 ! alkaline earth cation
is_a: CHEBI:39124 ! calcium ion

[Term]
id: CHEBI:39124
name: calcium ion
is_a: CHEBI:25213 ! metal cation
is_a: CHEBI:35155 ! elemental calcium

[Term]
id: CHEBI:39127
name: magnesium cation
def: "Any magnesium ion that is positively charged." []
is_a: CHEBI:33513 ! alkaline earth cation
is_a: CHEBI:39128 ! magnesium ion

[Term]
id: CHEBI:39128
name: magnesium ion
is_a: CHEBI:33973 ! elemental magnesium

[Term]
id: CHEBI:39129
name: strontium cation
is_a: CHEBI:33513 ! alkaline earth cation
is_a: CHEBI:39130 ! strontium ion

[Term]
id: CHEBI:39130
name: strontium ion
is_a: CHEBI:39131 ! elemental strontium

[Term]
id: CHEBI:39131
name: elemental strontium
is_a: CHEBI:37131 ! strontium molecular entity

[Term]
id: CHEBI:39141
name: Bronsted acid
def: "A molecular entity capable of donating a hydron to an acceptor (Brønsted base)." []
is_a: CHEBI:17891 ! donor
is_a: CHEBI:37527 ! acid

[Term]
id: CHEBI:39142
name: Bronsted base
def: "A molecular entity capable of accepting a hydron from a donor (Brønsted acid)." []
is_a: CHEBI:15339 ! acceptor
is_a: CHEBI:22695 ! base

[Term]
id: CHEBI:39143
name: Lewis acid
def: "A molecular entity that is an electron-pair acceptor and therefore able to form a covalent bond with an electron-pair donor (Lewis base), thereby producing a Lewis adduct." []
is_a: CHEBI:15339 ! acceptor
is_a: CHEBI:37527 ! acid

[Term]
id: CHEBI:39144
name: Lewis base
def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." []
is_a: CHEBI:17891 ! donor
is_a: CHEBI:22695 ! base

[Term]
id: CHEBI:39146
name: trichostatin
is_a: CHEBI:49319 ! carbocyclic antibiotic

[Term]
id: CHEBI:39150
name: 4-oxopentanoate
def: "A member of the class of oxopentanoates that is the conjugate base of 4-oxopentanoic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25798 ! oxopentanoates
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:45630 ! is deprotonated form of 4-oxopentanoic acid

[Term]
id: CHEBI:39154
name: chlorocyclohexane
def: "Any chlorocycloalkane that is cyclohexane substituted by at least one chlorine group." []
is_a: CHEBI:39155 ! chlorocycloalkane
relationship: RO:0018040 CHEBI:29005 ! has parent hydride cyclohexane

[Term]
id: CHEBI:39155
name: chlorocycloalkane
def: "A chlorohydrocarbon that is any cycloalkane substituted by at least one chloro group." []
is_a: CHEBI:23115 ! chlorohydrocarbon

[Term]
id: CHEBI:39157
name: trichostatic acid
is_a: CHEBI:35983 ! 7-oxo monocarboxylic acid
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid

[Term]
id: CHEBI:39158
name: (R)-trichostatic acid
is_a: CHEBI:39157 ! trichostatic acid
relationship: RO:0018039 CHEBI:39159 ! is enantiomer of (S)-trichostatic acid

[Term]
id: CHEBI:39159
name: (S)-trichostatic acid
is_a: CHEBI:39157 ! trichostatic acid
relationship: RO:0018039 CHEBI:39158 ! is enantiomer of (R)-trichostatic acid

[Term]
id: CHEBI:39161
name: 1,1,1-trichloro-2,2-diphenylethane
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0018040 CHEBI:38884 ! has parent hydride diphenylmethane

[Term]
id: CHEBI:39162
name: (R)-nicotine
def: "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has <i>R</i>-configuration." []
is_a: CHEBI:138000 ! 3-(1-methylpyrrolidin-2-yl)pyridine
relationship: RO:0018033 CHEBI:79008 ! is deprotonated form of (R)-nicotinium(1+)
relationship: RO:0018039 CHEBI:17688 ! is enantiomer of (S)-nicotine

[Term]
id: CHEBI:39163
name: acetamiprid
def: "A carboxamidine that is acetamidine in which the amino hydrogens are substituted by a (6-chloropyridin-3-yl)methyl and a methyl group while the hydrogen attached to the imino nitrogen is replaced by a cyano group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35359 ! carboxamidine
is_a: CHEBI:39172 ! monochloropyridine
relationship: RO:0000087 CHEBI:25540 ! has role neonicotinoid insectide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:39174 ! has functional parent 2-chloropyridine

[Term]
id: CHEBI:39164
name: (E)-acetamiprid
def: "The (<i>E</i>)-stereoisomer of acetamiprid." []
is_a: CHEBI:39163 ! acetamiprid

[Term]
id: CHEBI:39165
name: (Z)-acetamiprid
is_a: CHEBI:39163 ! acetamiprid

[Term]
id: CHEBI:39166
name: tetramine
def: "Any polyamine that contains four amino groups." []
is_a: CHEBI:88061 ! polyamine

[Term]
id: CHEBI:39168
name: (E)-imidacloprid
def: "The <i>E</i>-isomer of imidacloprid." []
is_a: CHEBI:5870 ! imidacloprid

[Term]
id: CHEBI:39169
name: (Z)-imidacloprid
def: "The <i>Z</i>-isomer of imidacloprid." []
is_a: CHEBI:5870 ! imidacloprid

[Term]
id: CHEBI:39172
name: monochloropyridine
def: "A chloropyridine in which only one chlorine is attached to the pyridine ring." []
is_a: CHEBI:39173 ! chloropyridine

[Term]
id: CHEBI:39173
name: chloropyridine
def: "Compounds containing a pyridine nucleus substituted with one or more chlorine atoms." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:39174
name: 2-chloropyridine
is_a: CHEBI:39172 ! monochloropyridine

[Term]
id: CHEBI:39175
name: thiacloprid
def: "A  nitrile that is cyanamide in which the hydrogens are replaced by a 1,3-thiazolidin-2-ylidene group which in turn is substituted by a (6-chloropyridin-3-yl)methyl group at the ring nitrogen." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35622 ! thiazolidines
is_a: CHEBI:39172 ! monochloropyridine
relationship: RO:0000087 CHEBI:25540 ! has role neonicotinoid insectide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:16698 ! has functional parent cyanamide
relationship: RO:0018038 CHEBI:39174 ! has functional parent 2-chloropyridine

[Term]
id: CHEBI:39176
name: (Z)-thiacloprid
def: "The (<i>Z</i>)-stereoisomer of thiacloprid." []
is_a: CHEBI:39175 ! thiacloprid

[Term]
id: CHEBI:39177
name: (E)-clothianidin
def: "A clothiadin that has <i>E</i> configuration at the C=N bond of the nitroguanidine moiety." []
is_a: CHEBI:39178 ! clothianidin

[Term]
id: CHEBI:39178
name: clothianidin
def: "An <em>N</em>-nitro compound consisting of 2-nitroguanidine having a (2-chloro-1,3-thiazol-5-yl)methyl group at position 1 and a methyl group at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38418 ! 1,3-thiazoles
is_a: CHEBI:84773 ! 2-nitroguanidine derivative
relationship: RO:0000087 CHEBI:25540 ! has role neonicotinoid insectide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:39187 ! has functional parent 2-chlorothiazole

[Term]
id: CHEBI:39179
name: nitroguanidine
def: "An <em>N</em>-nitro compound that is guanidine in which one of the hydrogens is replaced by a nitro group. It can exist in distinct tautomeric forms, as 1-nitroguanidine (a nitroimine) or 2-nitroguanidine (a nitroamine); in both solid and in solution, the nitroimine form predominates." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38780 ! N-nitro compound
relationship: RO:0000087 CHEBI:63490 ! has role explosive
relationship: RO:0018038 CHEBI:42820 ! has functional parent guanidine
relationship: RO:0018038 CHEBI:616459 ! has functional parent carbamimidoylazanium

[Term]
id: CHEBI:39180
name: 1-nitroguanidine
is_a: CHEBI:39179 ! nitroguanidine
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018036 CHEBI:39181 ! is tautomer of 2-nitroguanidine

[Term]
id: CHEBI:39181
name: 2-nitroguanidine
is_a: CHEBI:39179 ! nitroguanidine
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018036 CHEBI:39180 ! is tautomer of 1-nitroguanidine

[Term]
id: CHEBI:39185
name: thiamethoxam
def: "An oxadiazane that is tetrahydro-<em>N</em>-nitro-4<em>H</em>-1,3,5-oxadiazin-4-imine bearing (2-chloro-1,3-thiazol-5-yl)methyl and methyl substituents at positions 3 and 5 respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38418 ! 1,3-thiazoles
is_a: CHEBI:48898 ! oxadiazane
is_a: CHEBI:84773 ! 2-nitroguanidine derivative
relationship: RO:0000087 CHEBI:22583 ! has role antifeedant
relationship: RO:0000087 CHEBI:25540 ! has role neonicotinoid insectide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:39187 ! has functional parent 2-chlorothiazole

[Term]
id: CHEBI:39186
name: (E)-thiamethoxam
is_a: CHEBI:39185 ! thiamethoxam

[Term]
id: CHEBI:39187
name: 2-chlorothiazole
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38418 ! 1,3-thiazoles

[Term]
id: CHEBI:39189
name: organosulfur pesticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33261 ! organosulfur compound
relationship: RO:0000087 CHEBI:25944 ! has role pesticide

[Term]
id: CHEBI:39192
name: dithiolanes
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:39203
name: dibenzopyran
def: "Any organic heteropolycyclic compound based on a skeleton consisting of a pyran ring fused with two benzene rings." []
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:39205
name: dibenzopyrrole
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:39208
name: antibiotic insecticide
is_a: CHEBI:24852 ! insecticide
is_a: CHEBI:39215 ! antibiotic pesticide

[Term]
id: CHEBI:39209
name: macrolide insecticide
is_a: CHEBI:39221 ! macrolide pesticide
relationship: RO:0000087 CHEBI:39208 ! has role antibiotic insecticide

[Term]
id: CHEBI:39213
name: avermectin insecticide
is_a: CHEBI:39209 ! macrolide insecticide
is_a: CHEBI:39220 ! avermectin pesticide

[Term]
id: CHEBI:39214
name: abamectin
def: "Mixture of 80% avermectin B<small><sub>1a</sub></small> and 20% avermectin B<small><sub>1b</sub></small>." []
is_a: CHEBI:39213 ! avermectin insecticide
is_a: CHEBI:39219 ! avermectin acaricide
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:29534 ! has part avermectin B1a
relationship: BFO:0000051 CHEBI:29537 ! has part avermectin B1b
relationship: RO:0000087 CHEBI:39217 ! has role antibiotic nematicide

[Term]
id: CHEBI:39215
name: antibiotic pesticide
is_a: CHEBI:25944 ! pesticide
is_a: CHEBI:33281 ! antimicrobial agent

[Term]
id: CHEBI:39216
name: antibiotic acaricide
is_a: CHEBI:22153 ! acaricide
is_a: CHEBI:39215 ! antibiotic pesticide

[Term]
id: CHEBI:39217
name: antibiotic nematicide
is_a: CHEBI:25491 ! nematicide
is_a: CHEBI:39215 ! antibiotic pesticide

[Term]
id: CHEBI:39218
name: macrolide acaricide
is_a: CHEBI:39221 ! macrolide pesticide
relationship: RO:0000087 CHEBI:39216 ! has role antibiotic acaricide

[Term]
id: CHEBI:39219
name: avermectin acaricide
is_a: CHEBI:39218 ! macrolide acaricide
is_a: CHEBI:39220 ! avermectin pesticide

[Term]
id: CHEBI:39220
name: avermectin pesticide
is_a: CHEBI:39221 ! macrolide pesticide

[Term]
id: CHEBI:39221
name: macrolide pesticide
is_a: CHEBI:25105 ! macrolide antibiotic

[Term]
id: CHEBI:39226
name: chlorocarbon
def: "Compounds consisting wholly of chlorine and carbon." []
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:39227
name: hexachloroethane
def: "A member of the class of chloroethanes that is ethane in which all the hydrogens are replaced by chloro groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36016 ! chloroethanes
is_a: CHEBI:39226 ! chlorocarbon
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:39258
name: diphenyl ether
def: "An aromatic ether in which the oxygen is attached to two phenyl substituents. It has been found in muscat grapes and vanilla." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:39259
name: pyrethroid ester acaricide
is_a: CHEBI:22153 ! acaricide

[Term]
id: CHEBI:39260
name: pyriproxyfen
def: "An aromatic ether that consists of propylene glycol having a 2-pyridyl group at the O-1 position and a 4-phenoxyphenyl group at the O-3 position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:24942 ! has role juvenile hormone mimic
relationship: RO:0018038 CHEBI:39264 ! has functional parent 4-phenoxyphenol

[Term]
id: CHEBI:39262
name: phenoxyphenol
is_a: CHEBI:33853 ! phenols
relationship: RO:0018038 CHEBI:39258 ! has functional parent diphenyl ether

[Term]
id: CHEBI:39264
name: 4-phenoxyphenol
is_a: CHEBI:39262 ! phenoxyphenol

[Term]
id: CHEBI:39268
name: dibenzothiazepine
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:39270
name: naphthofuran
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:39275
name: bromomethane
def: "A one-carbon compound in which the carbon is attached by single bonds to three hydrogen atoms and one bromine atom. It is produced naturally by marine algae." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:25253 ! methyl halides
is_a: CHEBI:39278 ! bromomethanes
relationship: RO:0000087 CHEBI:39277 ! has role fumigant insecticide
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite

[Term]
id: CHEBI:39276
name: fumigant
def: "A volatile or volatilizable chemical compound utilized for control of pests in buildings, soil, grain, as well as during processing of goods to be imported or exported to prevent transfer of exotic organisms." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:39277
name: fumigant insecticide
is_a: CHEBI:24852 ! insecticide
is_a: CHEBI:39276 ! fumigant

[Term]
id: CHEBI:39278
name: bromomethanes
def: "A halomethane that is methane in which one or more hydrogens has been replaced by bromine." []
is_a: CHEBI:22929 ! bromoalkane
is_a: CHEBI:39279 ! halomethane

[Term]
id: CHEBI:39279
name: halomethane
def: "A haloalkane that is methane in which one (or more) of the hydrogens have been replaced by a halogen atom/halogen atoms." []
is_a: CHEBI:24469 ! haloalkane
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018040 CHEBI:16183 ! has parent hydride methane

[Term]
id: CHEBI:39281
name: fluoromethanes
def: "A halomethane that is methane in which one or more hydrogens has been replaced by fluorine." []
is_a: CHEBI:24067 ! fluoroalkane
is_a: CHEBI:39279 ! halomethane

[Term]
id: CHEBI:39282
name: iodomethane
def: "A member of the class of  iodomethanes that is methane in which one of the hydrogens is replaced by iodine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25253 ! methyl halides
is_a: CHEBI:39284 ! iodomethanes
relationship: RO:0000087 CHEBI:39277 ! has role fumigant insecticide

[Term]
id: CHEBI:39284
name: iodomethanes
def: "A halomethane that is methane in which one or more hydrogens has been replaced by iodine." []
is_a: CHEBI:37757 ! iodoalkane
is_a: CHEBI:39279 ! halomethane

[Term]
id: CHEBI:39285
name: chloropicrin
def: "A <em>C</em>-nitro compound that is nitromethane in which all three hydrogens are replaced by chlorines. It is a severe irritant, and can cause immediate, severe inflammation of the eyes, nose and throat, and significant injuries to the upper and lower respiratory tract. Formerly stockpiled as a chemical warfare agent, it has been widely used in the US as a soil fumigant, particularly for strawberry crops. It is not approved for use within the European Union." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:39277 ! has role fumigant insecticide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:39287
name: sulfuryl difluoride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39443 ! sulfuryl halide
relationship: RO:0000087 CHEBI:39277 ! has role fumigant insecticide

[Term]
id: CHEBI:39288
name: hexafluoroaluminate(3-)
is_a: CHEBI:36668 ! aluminium coordination entity
is_a: CHEBI:51528 ! perfluorometallate anion

[Term]
id: CHEBI:39289
name: trisodium hexafluoroaluminate
is_a: CHEBI:38702 ! inorganic sodium salt
is_a: CHEBI:51531 ! perfluorometallate salt
relationship: BFO:0000051 CHEBI:39288 ! has part hexafluoroaluminate(3-)

[Term]
id: CHEBI:39291
name: flonicamid
def: "A pyridinecarboxamide that is  nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:25529 ! pyridinecarboxamide
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:136644 ! has role proinsecticide
relationship: RO:0000087 CHEBI:22583 ! has role antifeedant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:231554 ! has functional parent flumetnicam

[Term]
id: CHEBI:39292
name: organotin acaricide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39293 ! organotin pesticide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide

[Term]
id: CHEBI:39293
name: organotin pesticide
is_a: CHEBI:25717 ! organotin compound

[Term]
id: CHEBI:39294
name: fenbutatin oxide
is_a: CHEBI:39292 ! organotin acaricide

[Term]
id: CHEBI:39298
name: organosulfur acaricide
is_a: CHEBI:39189 ! organosulfur pesticide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide

[Term]
id: CHEBI:39300
name: propargite
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39088 ! sulfite ester
is_a: CHEBI:73477 ! terminal acetylenic compound
relationship: RO:0000087 CHEBI:39301 ! has role sulfite ester acaricide

[Term]
id: CHEBI:39301
name: sulfite ester acaricide
is_a: CHEBI:22153 ! acaricide

[Term]
id: CHEBI:39308
name: 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0018038 CHEBI:23500 ! has functional parent cyclopropanecarboxylic acid

[Term]
id: CHEBI:39311
name: pymetrozine
def: "A member of the class of 1,2,4-triazines that is 4,5-dihydro-1,2,4-triazin-3(2<em>H</em>)-one substituted by a methyl group at position 6 and a (pyridin-3-ylmethylidene)amino group at position 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:39410 ! 1,2,4-triazines
relationship: RO:0000087 CHEBI:142782 ! has role TRPV channel modulator
relationship: RO:0000087 CHEBI:22583 ! has role antifeedant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:39316
name: mite growth regulator
is_a: CHEBI:22153 ! acaricide
is_a: CHEBI:39317 ! growth regulator

[Term]
id: CHEBI:39317
name: growth regulator
def: "Any chemical substance that inhibits the life-cycle of an organism." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:39318
name: tetrazine acaricide
is_a: CHEBI:22153 ! acaricide

[Term]
id: CHEBI:39319
name: 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid
def: "An organofluorine compound consisting of cyclopropanecarboxylic acid having a 2-chloro-3,3,3-trifluoroprop-1-en-1-yl group at the 3-position and two methyl groups at the 2-position." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0018038 CHEBI:23500 ! has functional parent cyclopropanecarboxylic acid

[Term]
id: CHEBI:39345
name: 2-(4-chlorophenyl)-3-methylbutyric acid
def: "A monocarboxylic acid consisting of isovaleric acid having a 4-chlorophenyl group at the 2-position." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0018038 CHEBI:28484 ! has functional parent isovaleric acid

[Term]
id: CHEBI:39349
name: 4,6-dinitro-o-cresol
def: "A hydroxytoluene that is <em>o</em>-cresol carrying nitro substituents at positions 4 and 6." []
is_a: CHEBI:24751 ! hydroxytoluene
is_a: CHEBI:25566 ! nitrotoluene
is_a: CHEBI:39363 ! dinitrophenol acaricide
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:39415 ! has role dinitrophenol insecticide
relationship: RO:0018038 CHEBI:28054 ! has functional parent o-cresol
relationship: RO:0018038 CHEBI:42017 ! has functional parent 2,4-dinitrophenol

[Term]
id: CHEBI:39351
name: pyrethroid ether insecticide
is_a: CHEBI:26413 ! pyrethroid insecticide

[Term]
id: CHEBI:39352
name: dinitrophenol
def: "Members of the class of  nitrophenol carrying two nitro substituents." []
is_a: CHEBI:25562 ! nitrophenol

[Term]
id: CHEBI:39353
name: fenpropathrin
def: "A cyclopropanecarboxylate ester obtained by formal condensation between  2,2,3,3-tetramethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0000087 CHEBI:39259 ! has role pyrethroid ester acaricide
relationship: RO:0018038 CHEBI:39355 ! has functional parent 2,2,3,3-tetramethylcyclopropanecarboxylic acid

[Term]
id: CHEBI:39355
name: 2,2,3,3-tetramethylcyclopropanecarboxylic acid
def: "A monocarboxylic acid consisting of cyclopropanecarboxylic acid having four methyl substituents." []
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0018038 CHEBI:23500 ! has functional parent cyclopropanecarboxylic acid

[Term]
id: CHEBI:39362
name: mononitrophenol
def: "A nitrophenol that is phenol carrying a single nitro substituent at unspecified position." []
is_a: CHEBI:25562 ! nitrophenol

[Term]
id: CHEBI:39363
name: dinitrophenol acaricide
is_a: CHEBI:39364 ! dinitrophenol pesticide
is_a: CHEBI:39366 ! organonitrogen acaricide

[Term]
id: CHEBI:39364
name: dinitrophenol pesticide
is_a: CHEBI:39365 ! organonitrogen pesticide

[Term]
id: CHEBI:39365
name: organonitrogen pesticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:25944 ! has role pesticide

[Term]
id: CHEBI:39366
name: organonitrogen acaricide
is_a: CHEBI:39365 ! organonitrogen pesticide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide

[Term]
id: CHEBI:39369
name: pyrethroid ether acaricide
is_a: CHEBI:22153 ! acaricide

[Term]
id: CHEBI:39378
name: homopteran inhibitor of chitin biosynthesis
is_a: CHEBI:23100 ! chitin synthesis inhibitor

[Term]
id: CHEBI:39379
name: lepidopteran inhibitor of chitin biosynthesis
is_a: CHEBI:23100 ! chitin synthesis inhibitor

[Term]
id: CHEBI:39387
name: teflubenzuron
def: "A <em>N</em>-acylurea that is <em>N</em>-carbamoyl-2,6-difluorobenzamide substituted by a 3,5-dichloro-2,4-difluorophenyl group at the terminal nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:38582 ! difluorobenzene
is_a: CHEBI:74266 ! N-acylurea
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:39416 ! has functional parent N-benzoylurea

[Term]
id: CHEBI:39397
name: tetramethrin
is_a: CHEBI:39398 ! phthalimide insecticide
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
is_a: CHEBI:55417 ! maleimides
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0018038 CHEBI:3680 ! has functional parent chrysanthemic acid

[Term]
id: CHEBI:39398
name: phthalimide insecticide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:82851 ! phthalimides
relationship: RO:0000087 CHEBI:24852 ! has role insecticide

[Term]
id: CHEBI:39410
name: 1,2,4-triazines
def: "Any compound with a 1,2,4-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 2 and 4 of the core benzene ring structure." []
is_a: CHEBI:38102 ! triazines

[Term]
id: CHEBI:39412
name: bridged diphenyl acaricide
is_a: CHEBI:22153 ! acaricide

[Term]
id: CHEBI:39415
name: dinitrophenol insecticide
is_a: CHEBI:24852 ! insecticide

[Term]
id: CHEBI:39416
name: N-benzoylurea
def: "An <em>N</em>-acylurea that is urea in which one of the hydrogens is replaced by a benzoyl group." []
is_a: CHEBI:74266 ! N-acylurea

[Term]
id: CHEBI:39417
name: branched-chain saturated fatty acid
def: "Any saturated fatty acid with a carbon side-chain or isopropyl termination." []
is_a: CHEBI:26607 ! saturated fatty acid
is_a: CHEBI:35819 ! branched-chain fatty acid
relationship: RO:0018034 CHEBI:58956 ! is protonated form of branched-chain saturated fatty acid anion

[Term]
id: CHEBI:39418
name: straight-chain saturated fatty acid
def: "Any saturated fatty acid lacking a side-chain." []
is_a: CHEBI:26607 ! saturated fatty acid
is_a: CHEBI:59202 ! straight-chain fatty acid
relationship: RO:0018034 CHEBI:58954 ! is protonated form of straight-chain saturated fatty acid anion

[Term]
id: CHEBI:39421
name: perfluorooctane-1-sulfonic acid
def: "A perfluoroalkanesulfonic acid that is octane-1-sulfonic acid in which all seventeen of the hydrogens that are attached to carbons have been replaced by fluorines." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132447 ! perfluoroalkanesulfonic acid
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0018038 CHEBI:39422 ! has functional parent octane-1-sulfonic acid

[Term]
id: CHEBI:39422
name: octane-1-sulfonic acid
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33551 ! organosulfonic acid
relationship: RO:0000087 CHEBI:36333 ! has role local anaesthetic

[Term]
id: CHEBI:39426
name: perfluorobutyric acid
def: "A monocarboxylic acid that is perfluorinated butyric acid." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:59745 ! has role chromatographic reagent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:30772 ! has functional parent butyric acid

[Term]
id: CHEBI:39429
name: hexafluoroacetone
def: "A  ketone that is acetone in which all the methyl hydrogens are replaced by fluoro groups." []
is_a: CHEBI:134091 ! perfluorinated compound
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:39430
name: dioxolane
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:39432
name: furochromene
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:39437
name: tocol
def: "A chromanol with a chroman-6-ol skeleton that is substituted at position 2 by a saturated or triply-unsaturated hydrocarbon chain consisting of three isoprenoid units." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23229 ! chromanol
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0018038 CHEBI:78631 ! has functional parent chroman-6-ol

[Term]
id: CHEBI:39442
name: fluorescent probe
def: "A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy." []
is_a: CHEBI:50406 ! probe

[Term]
id: CHEBI:39443
name: sulfuryl halide
is_a: CHEBI:37826 ! sulfuric acid derivative

[Term]
id: CHEBI:39444
name: diazo compound
def: "Compounds containing a group =N<small><sub>2</sub></small> attached to a single carbon atom. They are named by adding the prefix 'diazo-' to the name of the parent hydride or functional parent." []
is_a: CHEBI:35352 ! organonitrogen compound
relationship: BFO:0000051 CHEBI:30105 ! has part diazo group

[Term]
id: CHEBI:39446
name: pyrimidine ribonucleosides
is_a: CHEBI:18254 ! ribonucleoside
is_a: CHEBI:26440 ! pyrimidine nucleoside

[Term]
id: CHEBI:39447
name: pyrimidines
def: "Any compound having a pyrimidine as part of its structure." []
is_a: CHEBI:38313 ! diazines

[Term]
id: CHEBI:39456
name: antiglaucoma drug
def: "Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye." []
is_a: CHEBI:66981 ! ophthalmology drug

[Term]
id: CHEBI:39457
name: pyrimidine ribonucleoside 5'-monophosphate
is_a: CHEBI:26443 ! pyrimidine ribonucleoside monophosphate
is_a: CHEBI:26446 ! pyrimidine ribonucleotide
is_a: CHEBI:37010 ! ribonucleoside 5'-monophosphate

[Term]
id: CHEBI:39474
name: polyazaalkane
def: "Any azaalkane in which two or more carbons in the chain are replaced by nitrogen." []
is_a: CHEBI:46686 ! azaalkane
is_a: CHEBI:88061 ! polyamine

[Term]
id: CHEBI:39478
name: buta-1,3-diene
def: "A  butadiene with unsaturation at positions 1 and 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39479 ! butadiene
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:39479
name: butadiene
is_a: CHEBI:33646 ! alkadiene

[Term]
id: CHEBI:39481
name: chloroprene
is_a: CHEBI:39482 ! chloroolefin
relationship: RO:0018040 CHEBI:39478 ! has parent hydride buta-1,3-diene

[Term]
id: CHEBI:39482
name: chloroolefin
def: "A chlorohydrocarbon carrying one or more chloro groups at unspecified positions." []
is_a: CHEBI:23115 ! chlorohydrocarbon

[Term]
id: CHEBI:39548
name: atorvastatin
def: "A dihydroxy monocarboxylic acid that is a member of the drug class known as statins, used primarily for lowering blood cholesterol and for preventing cardiovascular diseases." []
is_a: CHEBI:26455 ! pyrroles
is_a: CHEBI:35972 ! dihydroxy monocarboxylic acid
is_a: CHEBI:62733 ! aromatic amide
is_a: CHEBI:83575 ! monofluorobenzenes
is_a: CHEBI:87635 ! statin (synthetic)
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:36335 ! has role trypanocidal drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:50690 ! is protonated form of atorvastatin(1-)
relationship: RO:0018038 CHEBI:45571 ! has functional parent heptanoic acid

[Term]
id: CHEBI:39589
name: (R)-bicalutamide
def: "A <em>N</em>-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide that is the (<i>R</i>)-enantiomer of bicalutamide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:144093 ! N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
relationship: RO:0000087 CHEBI:35497 ! has role androgen antagonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018039 CHEBI:144094 ! is enantiomer of (S)-bicalutamide

[Term]
id: CHEBI:3962
name: curcumin
def: "A β-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of <em>Curcuma longa</em>." []
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:51689 ! enone
is_a: CHEBI:67265 ! beta-diketone
is_a: CHEBI:78802 ! diarylheptanoid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:26130 ! has role biological pigment
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35856 ! has role lipoxygenase inhibitor
relationship: RO:0000087 CHEBI:37958 ! has role dye
relationship: RO:0000087 CHEBI:38157 ! has role iron chelator
relationship: RO:0000087 CHEBI:48550 ! has role EC 1.1.1.21 (aldehyde reductase) inhibitor
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:49323 ! has role contraceptive drug
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50390 ! has role EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:53746 ! has role EC 1.1.1.205 (IMP dehydrogenase) inhibitor
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64670 ! has role EC 1.8.1.9 (thioredoxin reductase) inhibitor
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0000087 CHEBI:76617 ! has role EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
relationship: RO:0000087 CHEBI:77182 ! has role food colouring
relationship: RO:0000087 CHEBI:77484 ! has role EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
relationship: RO:0018038 CHEBI:17620 ! has functional parent trans-ferulic acid

[Term]
id: CHEBI:39678
name: metsulfuron methyl
def: "A <em>N</em>-sulfonylurea in which the sulfonyl group is attached to a 2-(methoxycarbonyl)phenyl group while a (4-methoxy-6-methyl-1,3,5-triazin-2-yl group replaces one of the amino hydrogens of the remaining urea group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36054 ! benzoate ester
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:39745
name: dihydrogenphosphate
def: "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." []
is_a: CHEBI:35780 ! phosphate ion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018034 CHEBI:43474 ! is protonated form of hydrogenphosphate

[Term]
id: CHEBI:39832
name: methoxyethane
def: "An ether that is the methyl ether derivative of ethanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
relationship: RO:0000087 CHEBI:39144 ! has role Lewis base
relationship: RO:0018038 CHEBI:16236 ! has functional parent ethanol

[Term]
id: CHEBI:39867
name: valproic acid
def: "A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem." []
synonym: "2-propylpentanoic acid" EXACT [ChEMBL]
is_a: CHEBI:39417 ! branched-chain saturated fatty acid
is_a: CHEBI:62499 ! methyl-branched fatty acid
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35477 ! has role antimanic drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:51374 ! has role GABA agent
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0018034 CHEBI:60654 ! is protonated form of valproate
relationship: RO:0018038 CHEBI:17418 ! has functional parent valeric acid

[Term]
id: CHEBI:3992
name: cyclic ketone
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:39931
name: 3-nitrotoluene
def: "A mononitrotoluene carrying a nitro group at position 3." []
is_a: CHEBI:63171 ! mononitrotoluene

[Term]
id: CHEBI:40036
name: amitrole
def: "A member of the class of triazoles that is 1<em>H</em>-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties." []
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35727 ! triazoles
relationship: RO:0000087 CHEBI:138208 ! has role carotenoid biosynthesis inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:75380 ! has role EC 1.11.1.6 (catalase) inhibitor

[Term]
id: CHEBI:40116
name: propyl acetate
def: "An  acetate ester obtained by the formal condensation of acetic acid with propanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:48318 ! has role fragrance
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018038 CHEBI:28831 ! has functional parent propan-1-ol

[Term]
id: CHEBI:40235
name: 9H-purine-2,6-diamine
def: "A member of the class of 2,6-diaminopurines that is 9<em>H</em>-purine in which the hydrogens at positions 2 and 6 are replaced by amino groups." []
is_a: CHEBI:38001 ! 2,6-diaminopurines
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018038 CHEBI:16708 ! has functional parent adenine

[Term]
id: CHEBI:40237
name: sitagliptin
def: "A  triazolopyrazine that exhibits  hypoglycemic activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36963 ! organooxygen compound
is_a: CHEBI:48277 ! triazolopyrazine
is_a: CHEBI:83576 ! trifluorobenzene
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:48353 ! has role serine proteinase inhibitor
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:68612 ! has role EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:33706 ! has functional parent beta-amino acid

[Term]
id: CHEBI:4027
name: cyclophosphamide
def: "A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom." []
is_a: CHEBI:35467 ! phosphorodiamide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37598 ! nitrogen mustard
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:40279
name: allopurinol
def: "A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38669 ! pyrazolopyrimidine
is_a: CHEBI:67142 ! nucleobase analogue
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35634 ! has role EC 1.17.3.2 (xanthine oxidase) inhibitor
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018040 CHEBI:50092 ! has parent hydride 1H-pyrazolo[4,3-d]pyrimidine

[Term]
id: CHEBI:40303
name: lovastatin
def: "A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as <em>Aspergillus terreus</em> and <em>Pleurotus ostreatus</em> (oyster mushroom)." []
is_a: CHEBI:142348 ! hexahydronaphthalenes
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:26188 ! polyketide
is_a: CHEBI:35748 ! fatty acid ester
is_a: CHEBI:87632 ! statin (naturally occurring)
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76956 ! has role Aspergillus metabolite
relationship: RO:0018038 CHEBI:34848 ! has functional parent mevastatin
relationship: RO:0018038 CHEBI:38655 ! has functional parent (S)-2-methylbutyric acid

[Term]
id: CHEBI:4031
name: cyclosporin A
def: "A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle." []
is_a: CHEBI:24613 ! homodetic cyclic peptide
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:37153 ! has role EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
relationship: RO:0000087 CHEBI:49167 ! has role anti-asthmatic drug
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:4034
name: cyfluthrin
def: "A carboxylic ester obtained by formal condensation between 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid and (4-fluoro-3-phenoxyphenyl)(hydroxy)acetonitrile." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0018038 CHEBI:39308 ! has functional parent 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid

[Term]
id: CHEBI:4035
name: cyhalothrin
def: "A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0000087 CHEBI:39259 ! has role pyrethroid ester acaricide
relationship: RO:0018038 CHEBI:39319 ! has functional parent 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid

[Term]
id: CHEBI:4042
name: cypermethrin
def: "A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:33904 ! has role molluscicide
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0000087 CHEBI:39259 ! has role pyrethroid ester acaricide
relationship: RO:0018038 CHEBI:39308 ! has functional parent 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid

[Term]
id: CHEBI:4045
name: cyprodinil
def: "A member of the class of aminopyrimidine that is <em>N</em>-phenylpyrimidin-2-amine carrying additional cyclopropyl and methyl substituents at positions 4 and 6 respectively. A broad spectrum fungicide used to control a range of pathogens including <em>Tapesia yallundae</em>, <em>Botrytis</em> spp., <em>Alternaria</em> spp. and <em>Rhynchospium secalis</em>. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds as well as most aquatic organisms and earthworms, but it is not considered toxic to honeybees." []
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:87208 ! anilinopyrimidine fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:72768 ! has role aryl hydrocarbon receptor agonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:404903
name: ertapenem
def: "Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal  and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract." []
is_a: CHEBI:46634 ! carbapenemcarboxylic acid
is_a: CHEBI:46770 ! pyrrolidinecarboxamide
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0018034 CHEBI:60071 ! is protonated form of ertapenem(1-)

[Term]
id: CHEBI:40519
name: adamantane
synonym: "ADAMANTANE" EXACT [PDBeChem]
is_a: CHEBI:35713 ! polycyclic alkane
is_a: CHEBI:51339 ! adamantanes

[Term]
id: CHEBI:405237
name: L-canavanine zwitterion
def: "<small>L</small>-Canavanine in zwitterionic form." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018033 CHEBI:78902 ! is deprotonated form of L-canavanine(1+)
relationship: RO:0018036 CHEBI:609827 ! is tautomer of L-canavanine

[Term]
id: CHEBI:406059
name: cerivastatin(1-)
def: "The anion obtained by removal of a proton from the carboxylic acid group of cerivastatin." []
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0018033 CHEBI:3558 ! is deprotonated form of cerivastatin

[Term]
id: CHEBI:40751
name: (S)-adrenaline
def: "The <i>S</i>-enantiomer of adrenaline." []
is_a: CHEBI:194548 ! 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
relationship: RO:0018039 CHEBI:28918 ! is enantiomer of (R)-adrenaline

[Term]
id: CHEBI:40909
name: azoxystrobin
def: "An aryloxypyrimidine having a 4,6-diphenoxypyrimidine  skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c<small><sub>1</sub></small>, it is used widely as a fungicide in agriculture." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:47985 ! enol ether
is_a: CHEBI:48535 ! aryloxypyrimidine
is_a: CHEBI:86484 ! methoxyacrylate strobilurin antifungal agent
relationship: RO:0000087 CHEBI:141153 ! has role quinone outside inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:40910
name: azide anion
synonym: "azide" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36828 ! pseudohalide anion
relationship: RO:0000087 CHEBI:25355 ! has role mitochondrial respiratory-chain inhibitor
relationship: RO:0018033 CHEBI:29449 ! is deprotonated form of hydrogen azide

[Term]
id: CHEBI:40968
name: astaxanthin
def: "A carotenone that consists of β,β-carotene-4,4'-dione bearing two hydroxy substituents at positions 3 and 3' (the 3<i>S</i>,3'<i>S</i> diastereomer). A carotenoid pigment found mainly in animals (crustaceans, echinoderms) but also occurring in plants. It can occur free (as a red pigment), as an ester, or as a blue, brown or green chromoprotein." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23045 ! carotenol
is_a: CHEBI:35310 ! carotenone
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75767 ! has role animal metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77182 ! has role food colouring
relationship: RO:0018040 CHEBI:17579 ! has parent hydride beta-carotene

[Term]
id: CHEBI:41039
name: benfotiamine
def: "A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and <em>O</em>-phospohorylation." []
is_a: CHEBI:24079 ! formamides
is_a: CHEBI:25703 ! organic phosphate
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:51277 ! thioester
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:50267 ! has role protective agent
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical
relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant
relationship: RO:0000087 CHEBI:72470 ! has role provitamin B1
relationship: RO:0018038 CHEBI:18385 ! has functional parent thiamine(1+)

[Term]
id: CHEBI:41189
name: butane-1,4-diol
def: "A butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16°C) with a high boiling point (230°C), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13643 ! glycol
is_a: CHEBI:52684 ! butanediol
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:41218
name: mercaptoethanol
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:47908 ! alkanethiol
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector

[Term]
id: CHEBI:41275
name: 1H-benzimidazole
def: "The 1<em>H</em>-tautomer of benzimidazole." []
synonym: "BENZIMIDAZOLE" EXACT [PDBeChem]
synonym: "Benzimidazole" EXACT [KEGG_COMPOUND]
synonym: "benzimidazole" EXACT [IUPAC]
is_a: CHEBI:36622 ! benzimidazole
is_a: CHEBI:38180 ! polycyclic heteroarene
relationship: RO:0018034 CHEBI:33173 ! is protonated form of benzimidazolide
relationship: RO:0018036 CHEBI:36623 ! is tautomer of 4H-benzimidazole
relationship: RO:0018036 CHEBI:36639 ! is tautomer of 2H-benzimidazole
relationship: RO:0018036 CHEBI:36641 ! is tautomer of 3aH-benzimidazole

[Term]
id: CHEBI:41308
name: benzophenone
def: "The simplest member of the class of benzophenones, being formaldehyde in which both hydrogens are replaced by phenyl groups." []
synonym: "Benzophenone" EXACT [KEGG_COMPOUND]
synonym: "DIPHENYLMETHANONE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22726 ! benzophenones
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:41320
name: 1,3-diphenylurea
def: "A member of the class of phenylureas that is urea in which one of the hydrogens of each amino group is replaced by a phenyl group. It is present in coconut milk (<em>Cocos nucifera</em>)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134043 ! phenylureas
relationship: RO:0000087 CHEBI:23530 ! has role cytokinin
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:41402
name: carboxymethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group
relationship: RO:0018037 CHEBI:15366 ! is substitutent group from acetic acid

[Term]
id: CHEBI:41423
name: celecoxib
def: "A member of the class of pyrazoles that is 1<em>H</em>-pyrazole which is substituted at positions 1, 3 and 5 by 4-sulfamoylphenyl, trifluoromethyl and <em>p</em>-tolyl groups, respectively. A cyclooxygenase-2 inhibitor, it is used in the treatment of arthritis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:27024 ! toluenes
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50629 ! has role cyclooxygenase 2 inhibitor
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:41550
name: fluoroform
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39281 ! fluoromethanes
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:41607
name: crotonaldehyde
def: "An enal consisting of propene having a formyl group at the 1-position." []
is_a: CHEBI:51688 ! enal

[Term]
id: CHEBI:41609
name: carbonate
is_a: CHEBI:35604 ! carbon oxoanion
relationship: RO:0018033 CHEBI:17544 ! is deprotonated form of hydrogencarbonate

[Term]
id: CHEBI:4167
name: D-glucopyranose
def: "A glucopyranose having <small>D</small>-configuration." []
is_a: CHEBI:17634 ! D-glucose
is_a: CHEBI:37661 ! glucopyranose
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76916 ! has role hyperglycemic agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:41774
name: tamoxifen
is_a: CHEBI:26776 ! stilbenoid
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:37700 ! has role EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50739 ! has role estrogen receptor modulator
relationship: RO:0000087 CHEBI:50792 ! has role estrogen receptor antagonist
relationship: RO:0000087 CHEBI:50837 ! has role estrogen antagonist
relationship: RO:0000087 CHEBI:62872 ! has role EC 1.2.3.1 (aldehyde oxidase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0018040 CHEBI:26775 ! has parent hydride stilbene

[Term]
id: CHEBI:41808
name: decane
def: "A straight-chain alkane with 10 carbon atoms." []
synonym: "DECANE" EXACT [PDBeChem]
is_a: CHEBI:18310 ! alkane

[Term]
id: CHEBI:41879
name: dexamethasone
def: "A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of  glucocorticoids." []
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:50830 ! fluorinated steroid
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:37962 ! has role adrenergic agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50671 ! has role antithyroid drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:41899
name: decylamine-N,N-dimethyl-N-oxide
def: "A tertiary amine oxide that is the <em>N</em>-oxide of <em>N</em>,<em>N</em>-dimethyldecan-1-amine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134363 ! tertiary amine oxide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:41921
name: 1H-indene
def: "An <em>ortho</em>-fused bicyclic arene comprising of benzene and cyclopentene rings." []
synonym: "INDENE" EXACT [PDBeChem]
synonym: "indene" EXACT [NIST_Chemistry_WebBook]
is_a: CHEBI:35426 ! ortho-fused bicyclic arene
is_a: CHEBI:37910 ! indene

[Term]
id: CHEBI:41922
name: diethylstilbestrol
def: "An olefinic compound that is <i>trans</i>-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by <em>p</em>-hydroxyphenyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:26776 ! stilbenoid
relationship: RO:0000087 CHEBI:137626 ! has role EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor
relationship: RO:0000087 CHEBI:138880 ! has role autophagy inducer
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:49200 ! has role EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:76988 ! has role xenoestrogen

[Term]
id: CHEBI:4194
name: D-hexose
def: "A hexose that has <small>D</small>-configuration at position 5." []
is_a: CHEBI:18133 ! hexose

[Term]
id: CHEBI:41941
name: (3,4-dihydroxyphenyl)acetic acid
def: "A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine." []
is_a: CHEBI:33566 ! catechols
is_a: CHEBI:61409 ! dihydroxyphenylacetic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17612 ! is protonated form of (3,4-dihydroxyphenyl)acetate
relationship: RO:0018038 CHEBI:30745 ! has functional parent phenylacetic acid

[Term]
id: CHEBI:41948
name: eflornithine
def: "A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2." []
is_a: CHEBI:24068 ! fluoroamino acid
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36335 ! has role trypanocidal drug
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent
relationship: RO:0018038 CHEBI:18257 ! has functional parent ornithine

[Term]
id: CHEBI:41977
name: daunorubicin
def: "A natural product found in <em>Actinomadura roseola</em>." []
is_a: CHEBI:22507 ! aminoglycoside antibiotic
is_a: CHEBI:25830 ! p-quinones
is_a: CHEBI:48120 ! anthracycline
is_a: CHEBI:51286 ! tetracenequinones
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018033 CHEBI:64677 ! is deprotonated form of daunorubicin(1+)
relationship: RO:0018040 CHEBI:32600 ! has parent hydride tetracene

[Term]
id: CHEBI:41983
name: 4'-epidoxorubicinium
def: "An anthracycline cation resulting from the protonation of the amino group of 4'-epidoxorubicin." []
is_a: CHEBI:64678 ! anthracycline cation
relationship: RO:0018034 CHEBI:47898 ! is protonated form of 4'-epidoxorubicin
relationship: RO:0018038 CHEBI:28748 ! has functional parent doxorubicin

[Term]
id: CHEBI:420128
name: 5-chlorosalicylic acid
def: "A monohydroxybenzoic acid that is 2-hydroxybenzoic acid (salicylic acid) in which the hydrogen at position 5 is replaced by chlorine." []
is_a: CHEBI:23134 ! chlorobenzoic acid
is_a: CHEBI:25389 ! monohydroxybenzoic acid
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0018034 CHEBI:59131 ! is protonated form of 5-chlorosalicylate

[Term]
id: CHEBI:42017
name: 2,4-dinitrophenol
def: "A dinitrophenol having the nitro groups at the 2- and 4-positions." []
synonym: "2,4-DINITROPHENOL" EXACT [PDBeChem]
synonym: "2,4-Dinitrophenol" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39352 ! dinitrophenol
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:73267 ! has role oxidative phosphorylation inhibitor
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0018034 CHEBI:84561 ! is protonated form of 2,4-dinitrophenol(1-)

[Term]
id: CHEBI:42068
name: idarubicin
is_a: CHEBI:35315 ! deoxy hexoside
is_a: CHEBI:49322 ! anthracycline antibiotic
is_a: CHEBI:63367 ! monosaccharide derivative
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018040 CHEBI:32600 ! has parent hydride tetracene

[Term]
id: CHEBI:42111
name: (R)-lactic acid
def: "An optically active form of lactic acid having (<i>R</i>)-configuration." []
is_a: CHEBI:78320 ! 2-hydroxypropanoic acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16004 ! is protonated form of (R)-lactate
relationship: RO:0018039 CHEBI:422 ! is enantiomer of (S)-lactic acid

[Term]
id: CHEBI:421707
name: abacavir
def: "A 2,6-diaminopurine that is (1<i>S</i>)-cyclopent-2-en-1-ylmethanol in which the <em>pro</em>-<i>R</i> hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9<em>H</em>-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26394 ! purine nucleoside
is_a: CHEBI:38001 ! 2,6-diaminopurines
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:421840
name: O-methylsalicylic acid
def: "A  methoxybenzoic acid that is the methyl ether of salicylic acid." []
is_a: CHEBI:25238 ! methoxybenzoic acid
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0018034 CHEBI:59128 ! is protonated form of O-methylsalicylate

[Term]
id: CHEBI:42191
name: EDTA(4-)
def: "A tetracarboxylic acid anion formed by deprotonation of all four carboxy groups in ethylenediaminetetraacetic acid (EDTA)." []
is_a: CHEBI:35754 ! tetracarboxylic acid anion
relationship: RO:0018033 CHEBI:63131 ! is deprotonated form of EDTA(3-)

[Term]
id: CHEBI:422
name: (S)-lactic acid
def: "An optically active form of lactic acid having (<i>S</i>)-configuration." []
is_a: CHEBI:17375 ! (2S)-2-hydroxy monocarboxylic acid
is_a: CHEBI:78320 ! 2-hydroxypropanoic acid
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16651 ! is protonated form of (S)-lactate
relationship: RO:0018039 CHEBI:42111 ! is enantiomer of (R)-lactic acid

[Term]
id: CHEBI:42223
name: emodin
def: "A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37488 ! trihydroxyanthraquinone
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:77659 ! is protonated form of emodin(1-)
relationship: RO:0018038 CHEBI:150013 ! has functional parent emodin anthrone

[Term]
id: CHEBI:42266
name: ethane
def: "An alkane comprising of two carbon atoms." []
synonym: "ETHANE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:42355
name: erythromycin A
def: "An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-<em>C</em>-methyl-3-<em>O</em>-methyl-α-<small>L</small>-<i>ribo</i>-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-<i>xylo</i>-hexopyranosyl residues attahced at positions 4 and 6 respectively." []
synonym: "ERYTHROMYCIN" EXACT [ChEMBL]
synonym: "Erythromycin" EXACT [ChEMBL, KEGG_COMPOUND]
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:48923 ! erythromycin
relationship: RO:0018033 CHEBI:64268 ! is deprotonated form of erythromycin A(1+)
relationship: RO:0018038 CHEBI:48848 ! has functional parent erythronolide A

[Term]
id: CHEBI:42471
name: forskolin
def: "A labdane diterpenoid isolated from the Indian <em>Coleus</em> plant." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:27136 ! triol
is_a: CHEBI:36615 ! triterpenoid
is_a: CHEBI:36770 ! labdane diterpenoid
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78547 ! has role protein kinase A agonist
relationship: RO:0000087 CHEBI:78548 ! has role adenylate cyclase agonist

[Term]
id: CHEBI:42485
name: formyl group
is_a: CHEBI:27207 ! univalent carboacyl group
relationship: RO:0018037 CHEBI:30751 ! is substitutent group from formic acid

[Term]
id: CHEBI:42492
name: fluorescin
is_a: CHEBI:38835 ! xanthenes

[Term]
id: CHEBI:42567
name: fisetin
def: "A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27741 ! 3'-hydroxyflavonoid
is_a: CHEBI:38684 ! tetrahydroxyflavone
is_a: CHEBI:52267 ! 7-hydroxyflavonol
is_a: CHEBI:72010 ! hydroxyflavan
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:71992 ! is protonated form of fisetin(1-)

[Term]
id: CHEBI:425902
name: propiophenone
def: "An aromatic ketone in which the two substituents on the carbonyl C atom are phenyl and ethyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:48318 ! has role fragrance

[Term]
id: CHEBI:42724
name: (R)-amphetamine
def: "A 1-phenylpropan-2-amine that has <i>R</i> configuration." []
is_a: CHEBI:132233 ! 1-phenylpropan-2-amine
is_a: CHEBI:35338 ! amphetamines
relationship: RO:0018039 CHEBI:4469 ! is enantiomer of (S)-amphetamine

[Term]
id: CHEBI:42797
name: gabapentin
def: "A γ-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome." []
is_a: CHEBI:33707 ! gamma-amino acid
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:16865 ! has functional parent gamma-aminobutyric acid

[Term]
id: CHEBI:42820
name: guanidine
def: "An aminocarboxamidine, the parent compound of the guanidines." []
synonym: "GUANIDINE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:35359 ! carboxamidine
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018033 CHEBI:30087 ! is deprotonated form of guanidinium

[Term]
id: CHEBI:42843
name: glycinamide
is_a: CHEBI:22475 ! amino acid amide
is_a: CHEBI:24373 ! glycine derivative

[Term]
id: CHEBI:42896
name: 1-thio-beta-D-glucopyranose
def: "A thiosugar that is β-<small>D</small>-glucopyranose in which the hydroxy group at position 1 is replaced by a sulfanyl group" []
is_a: CHEBI:29256 ! thiol
is_a: CHEBI:63367 ! monosaccharide derivative
is_a: CHEBI:73754 ! thiosugar
relationship: RO:0018038 CHEBI:15903 ! has functional parent beta-D-glucose

[Term]
id: CHEBI:42939
name: cyclohexylammonium
def: "An ammonium ion resulting from the protonation of the amino group of cyclohexylamine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:15773 ! is protonated form of cyclohexylamine

[Term]
id: CHEBI:43035
name: (R)-hydratropic acid
def: "The (<i>R</i>)-enantiomer of hydratropic acid." []
is_a: CHEBI:48526 ! hydratropic acid
relationship: RO:0018039 CHEBI:48527 ! is enantiomer of (S)-hydratropic acid

[Term]
id: CHEBI:43098
name: heptane
def: "A straight-chain alkane with seven carbon atoms. It has been found in Jeffrey pine (<em>Pinus jeffreyi</em>)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:43176
name: hydroxy group
is_a: CHEBI:33246 ! inorganic group

[Term]
id: CHEBI:43254
name: (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one
is_a: CHEBI:38337 ! pyrimidone
relationship: RO:0018036 CHEBI:17568 ! is tautomer of uracil

[Term]
id: CHEBI:43355
name: indoxyl sulfate
def: "An aryl sulfate that is indoxyl in which the hydroxyl hydrogen is substituted by a sulfo group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24828 ! indoles
is_a: CHEBI:37919 ! aryl sulfate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:144643 ! is protonated form of indoxyl sulfate(1-)
relationship: RO:0018038 CHEBI:17840 ! has functional parent indoxyl

[Term]
id: CHEBI:43415
name: dexibuprofen
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:5855 ! ibuprofen
relationship: RO:0018039 CHEBI:47835 ! is enantiomer of levibuprofen

[Term]
id: CHEBI:43451
name: hydrogen iodide
def: "A diatomic molecule containing covalently bonded hydrogen and iodine atoms." []
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18140 ! hydrogen halide
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:50317 ! is deprotonated form of iodonium
relationship: RO:0018034 CHEBI:16382 ! is protonated form of iodide

[Term]
id: CHEBI:43474
name: hydrogenphosphate
def: "A phosphate ion that is the conjugate base of dihydrogenphosphate." []
is_a: CHEBI:35780 ! phosphate ion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:39745 ! is deprotonated form of dihydrogenphosphate
relationship: RO:0018034 CHEBI:18367 ! is protonated form of phosphate(3-)

[Term]
id: CHEBI:43572
name: kojic acid
def: "A pyranone that is 4<em>H</em>-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus <em>Aspergillus oryzae</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131906 ! 4-pyranones
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:33823 ! enol
relationship: RO:0000087 CHEBI:59997 ! has role EC 1.14.18.1 (tyrosinase) inhibitor
relationship: RO:0000087 CHEBI:73240 ! has role NF-kappaB inhibitor
relationship: RO:0000087 CHEBI:76956 ! has role Aspergillus metabolite
relationship: RO:0000087 CHEBI:85046 ! has role skin lightening agent
relationship: RO:0000087 CHEBI:85049 ! has role EC 1.10.3.1 (catechol oxidase) inhibitor
relationship: RO:0000087 CHEBI:85050 ! has role EC 1.10.3.2 (laccase) inhibitor
relationship: RO:0000087 CHEBI:85051 ! has role EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor
relationship: RO:0000087 CHEBI:85052 ! has role EC 1.4.3.3 (D-amino-acid oxidase) inhibitor
relationship: RO:0018040 CHEBI:35593 ! has parent hydride 4H-pyran

[Term]
id: CHEBI:43602
name: obeticholic acid
def: "A dihydroxy-5β-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6α-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis." []
is_a: CHEBI:23775 ! dihydroxy-5beta-cholanic acid
is_a: CHEBI:3098 ! bile acid
is_a: CHEBI:36835 ! 3alpha-hydroxy steroid
is_a: CHEBI:36843 ! 7alpha-hydroxy steroid
relationship: RO:0000087 CHEBI:132972 ! has role farnesoid X receptor agonist
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018038 CHEBI:16755 ! has functional parent chenodeoxycholic acid

[Term]
id: CHEBI:43745
name: pyrimidine-2,4-diamine
def: "An aminopyrimidine in which a pyrimidine nucleus is substituted with amino groups at C-2 and C-4." []
is_a: CHEBI:38338 ! aminopyrimidine

[Term]
id: CHEBI:43799
name: butan-1-amine
def: "A primary aliphatic amine that is butane substituted by an amino group at position 1." []
is_a: CHEBI:17062 ! primary aliphatic amine

[Term]
id: CHEBI:43830
name: 3,7-bis(dimethylamino)phenothiazin-5-ium
def: "An organic cation that is phenothiazin-5-ium substituted by dimethylamino groups at positions 3 and 7. The chloride salt is the histological dye 'methylene blue'." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:78523 ! is protonated form of 3,7-bis(dimethylamino)phenothiazine

[Term]
id: CHEBI:43871
name: fasudil
def: "An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24922 ! isoquinolines
is_a: CHEBI:46946 ! N-sulfonyldiazepane
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:50925 ! has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:66980 ! has role nootropic agent
relationship: RO:0018033 CHEBI:180694 ! is deprotonated form of fasudil(1+)

[Term]
id: CHEBI:43966
name: melagatran
def: "A member of the class of azetidines that is (2<i>S</i>)-azetidine 2-carboxylic acid in which the carboxylic acid has been converted to the amide corresponding to formal condensation with 4-(aminomethyl)benzenecarboximidamide and in which the hydrogen attached to the azetidine nitrogen is replaced by a (2<i>R</i>)-2-cyclohexyl-2-[(carboxymethyl)amino]acetyl group." []
is_a: CHEBI:35359 ! carboxamidine
is_a: CHEBI:35735 ! dicarboxylic acid monoamide
is_a: CHEBI:38777 ! azetidines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:64926 ! has role serine protease inhibitor
relationship: RO:0000087 CHEBI:65232 ! has role EC 3.4.21.5 (thrombin) inhibitor

[Term]
id: CHEBI:43968
name: meropenem
def: "A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively." []
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:46634 ! carbapenemcarboxylic acid
is_a: CHEBI:46770 ! pyrrolidinecarboxamide
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:44107
name: malachite green cation
def: "An iminium ion obtained by dimethylation of the imino group of 4-{[4-(dimethylamino)phenyl](phenyl)methylene}cyclohexa-2,5-dien-1-imine. Used in the form of its chloride salt as a green-coloured dye." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35286 ! iminium ion
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:44156
name: terbutryn
def: "A methylthio-1,3,5-triazine that is 2-(methylsulfanyl)-1,3,5-triazine substituted by a <em>tert</em>-butylamino and an ethylamino group at positions 2 and 4 respectively." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38174 ! methylthio-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:44185
name: methotrexate
is_a: CHEBI:24315 ! glutamic acid derivative
is_a: CHEBI:26373 ! pteridines
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35692 ! dicarboxylic acid
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50683 ! has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor
relationship: RO:0000087 CHEBI:50691 ! has role abortifacient
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018034 CHEBI:50680 ! is protonated form of methotrexate(1-)
relationship: RO:0018038 CHEBI:16015 ! has functional parent L-glutamic acid

[Term]
id: CHEBI:44229
name: naphthalene-2-sulfonic acid
def: "A naphthalenesulfonic acid in which the sulfo group is linked to position 2 of the naphthalene ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36336 ! naphthalenesulfonic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:443725
name: fosmidomycin
def: "Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from <em>Streptomyces lavendulae</em>, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24650 ! hydroxamic acid
is_a: CHEBI:26069 ! phosphonic acids
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77654 ! has role EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor

[Term]
id: CHEBI:44383
name: N-methyl urea
def: "A member of the class of ureas that is urea substituted by a methyl group at one of the nitrogen atoms." []
is_a: CHEBI:47857 ! ureas

[Term]
id: CHEBI:44423
name: hydroxyurea
def: "A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease." []
synonym: "N-HYDROXYUREA" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36963 ! organooxygen compound
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:64911 ! has role antimitotic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:74213 ! has role EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:28976 ! has functional parent carbonic acid

[Term]
id: CHEBI:4445
name: desflurane
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0018038 CHEBI:39832 ! has functional parent methoxyethane

[Term]
id: CHEBI:44557
name: nitrilotriacetic acid
is_a: CHEBI:27093 ! tricarboxylic acid
is_a: CHEBI:39054 ! NTA
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50909 ! has role nephrotoxic agent
relationship: RO:0018034 CHEBI:39053 ! is protonated form of nitrilotriacetate(1-)

[Term]
id: CHEBI:44658
name: okadaic acid
def: "A polycyclic ether that is produced by several species of dinoflagellates, and is known to accumulate in both marine sponges and shellfish.  A polyketide, polyether derivative of a C<small><sub>38</sub></small> fatty acid, it is one of the primary causes of diarrhetic shellfish poisoning (DSP). It is a potent inhibitor of specific protein phosphatases and is known to have a variety of negative effects on cells." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36468 ! polycyclic ether
relationship: RO:0000087 CHEBI:22986 ! has role calcium ionophore
relationship: RO:0000087 CHEBI:37153 ! has role EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite

[Term]
id: CHEBI:4466
name: dexmedetomidine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38975 ! methylbenzene
is_a: CHEBI:48552 ! medetomidine
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35569 ! has role alpha-adrenergic agonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35717 ! has role sedative
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018039 CHEBI:48555 ! is enantiomer of levomedetomidine

[Term]
id: CHEBI:44667
name: L-ornithinium(2+)
def: "The <small>L</small>-enantiomer of ornithinium(2+)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:46913 ! ornithinium(2+)
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:46911 ! is protonated form of L-ornithinium(1+)

[Term]
id: CHEBI:44672
name: 3'-phosphate-adenosine-5'-diphosphate
def: "An adenosine 3'-phosphate that is ADP carrying a phospate group at the 3'-position. It is potent inhibitor of bovine pancreatic ribonuclease A." []
is_a: CHEBI:37096 ! adenosine 5'-phosphate
is_a: CHEBI:37097 ! adenosine 3'-phosphate
relationship: RO:0018038 CHEBI:16761 ! has functional parent ADP

[Term]
id: CHEBI:4469
name: (S)-amphetamine
def: "A 1-phenylpropan-2-amine that has <i>S</i> configuration." []
is_a: CHEBI:132233 ! 1-phenylpropan-2-amine
is_a: CHEBI:35338 ! amphetamines
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:51039 ! has role dopamine uptake inhibitor
relationship: RO:0018039 CHEBI:42724 ! is enantiomer of (R)-amphetamine

[Term]
id: CHEBI:4470
name: dextromethorphan
def: "A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2<em>H</em>-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have <i>S</i>-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough." []
is_a: CHEBI:146178 ! 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
relationship: RO:0000087 CHEBI:146270 ! has role oneirogen
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:29133 ! has functional parent dextrorphan
relationship: RO:0018039 CHEBI:146176 ! is enantiomer of levomethorphan

[Term]
id: CHEBI:44785
name: peroxide
is_a: CHEBI:33263 ! diatomic oxygen

[Term]
id: CHEBI:44811
name: 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
def: "A 2-acetyl-1-alkyl-<em>sn</em>-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36707 ! 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50141 ! has role bronchoconstrictor agent
relationship: RO:0000087 CHEBI:50248 ! has role hematologic agent

[Term]
id: CHEBI:4488
name: diallyl disulfide
def: "An organic disulfide where the organic group specified is allyl. It has been isolated from garlic and other species of the genus <em>Allium</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35489 ! organic disulfide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:44884
name: pentan-1-ol
def: "A short-chain primary fatty alcohol that is pentane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It has been isolated from <em>Melicope ptelefolia</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:143597 ! pentanol
is_a: CHEBI:157770 ! short-chain primary fatty alcohol
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:44915
name: propofol
def: "A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:38976 ! alkylbenzene
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35717 ! has role sedative
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:38877 ! has role intravenous anaesthetic
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:44932
name: acepromazine
def: "A member of the class of  phenothiazines that is 10<em>H</em>-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10." []
is_a: CHEBI:38093 ! phenothiazines
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:51867 ! methyl ketone
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:37930 ! has role phenothiazine antipsychotic drug

[Term]
id: CHEBI:44976
name: phosphonic acid
def: "A phosphorus oxoacid that consists of a single pentavalent phosphorus covalently bound via single bonds to a single hydrogen and two hydroxy groups and via a double bond to an oxygen. The parent of the class of phosphonic acids." []
is_a: CHEBI:26069 ! phosphonic acids
is_a: CHEBI:33457 ! phosphorus oxoacid
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0018034 CHEBI:33462 ! is protonated form of phosphonate(1-)
relationship: RO:0018036 CHEBI:36361 ! is tautomer of phosphorous acid

[Term]
id: CHEBI:4503
name: Dichloroacetylene
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:45064
name: phosphite(3-)
def: "A trivalent inorganic anion obtained by removal of all three protons from phosphorous acid." []
is_a: CHEBI:26045 ! phosphite ion
is_a: CHEBI:79387 ! trivalent inorganic anion
relationship: RO:0018033 CHEBI:29259 ! is deprotonated form of hydrogenphosphite

[Term]
id: CHEBI:4510
name: diclofop-methyl
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-diclofop-methyl. A proherbicide for diclofop, it is used for the control of wild oats and annual weeds in wheat, barley, rye and broad-leaved crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:145413 ! has part (R)-diclofop-methyl
relationship: BFO:0000051 CHEBI:145414 ! has part (S)-diclofop-methyl
relationship: RO:0000087 CHEBI:136646 ! has role proherbicide
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
relationship: RO:0018038 CHEBI:81909 ! has functional parent diclofop

[Term]
id: CHEBI:45133
name: pivalic acid
def: "A branched, short-chain fatty acid composed of propanoic acid having two methyl substituents at the 2-position." []
is_a: CHEBI:26666 ! short-chain fatty acid
is_a: CHEBI:39417 ! branched-chain saturated fatty acid
is_a: CHEBI:62499 ! methyl-branched fatty acid
relationship: RO:0018034 CHEBI:63894 ! is protonated form of pivalate

[Term]
id: CHEBI:45212
name: diphosphate(2-)
def: "A divalent inorganic anion obtained by removal of both protons from diphosphoric acid." []
is_a: CHEBI:35782 ! diphosphate ion
is_a: CHEBI:79388 ! divalent inorganic anion
relationship: RO:0018033 CHEBI:33017 ! is deprotonated form of diphosphate(1-)
relationship: RO:0018034 CHEBI:33019 ! is protonated form of diphosphate(3-)

[Term]
id: CHEBI:45296
name: hexadecane
def: "A straight-chain alkane with 16 carbon atoms. It is a component of essential oil isolated from long pepper." []
synonym: "HEXADECANE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:83563 ! long-chain alkane
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent

[Term]
id: CHEBI:45373
name: sulfanilamide
def: "A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position." []
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:87228 ! sulfonamide antibiotic
relationship: RO:0000087 CHEBI:23018 ! has role EC 4.2.1.1 (carbonic anhydrase) inhibitor
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:45379
name: methylcarbamic acid
def: "An amino acid consisting of carbamic acid having an <em>N</em>-methyl substituent." []
is_a: CHEBI:33709 ! amino acid
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0018034 CHEBI:193111 ! is protonated form of methylcarbamate
relationship: RO:0018038 CHEBI:28616 ! has functional parent carbamic acid

[Term]
id: CHEBI:45409
name: ritonavir
def: "An <small>L</small>-valine derivative that is <small>L</small>-valinamide in which α-amino group has been acylated by a [(2-isopropyl-1,3-thiazol-4-yl)methyl]methylcarbamoyl group and in which a hydrogen of the carboxamide amino group has been replaced by a (2<i>R</i>,4<i>S</i>,5<i>S</i>)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl group. A CYP<small><sub>3</sub></small>A inhibitor and antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS, it is often used as a fixed-dose combination with another protease inhibitor, lopinavir. Also used in combination with dasabuvir sodium hydrate, ombitasvir and paritaprevir (under the trade name Viekira Pak) for treatment of chronic hepatitis C virus genotype 1 infection as well as cirrhosis of the liver." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:21689 ! N-carbamoyl-amino acid
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:38418 ! 1,3-thiazoles
is_a: CHEBI:84129 ! L-valine derivative
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35660 ! has role HIV protease inhibitor
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:45453
name: sinefungin
def: "An adenosine that is the the δ-(5'-adenosyl) derivative of ornithine." []
is_a: CHEBI:22260 ! adenosines
is_a: CHEBI:36988 ! 5'-deoxyribonucleoside
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0018038 CHEBI:15729 ! has functional parent L-ornithine

[Term]
id: CHEBI:45525
name: (R)-2-methylbutyric acid
def: "The (<i>R</i>)-enantiomer of 2-methylbutanoic acid." []
synonym: "2-METHYLBUTANOIC ACID" EXACT [PDBeChem]
is_a: CHEBI:37070 ! 2-methylbutyric acid
relationship: RO:0018039 CHEBI:38655 ! is enantiomer of (S)-2-methylbutyric acid

[Term]
id: CHEBI:45557
name: sec-butyl group
is_a: CHEBI:22323 ! alkyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group
relationship: RO:0018037 CHEBI:37808 ! is substitutent group from butane

[Term]
id: CHEBI:45571
name: heptanoic acid
def: "A C<small><sub>7</sub></small>, straight-chain fatty acid that contributes to the odour of some rancid oils. Used in the preparation of esters for the fragrance industry, and as an additive in cigarettes." []
synonym: "HEPTANOIC ACID" EXACT [PDBeChem]
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
is_a: CHEBI:59554 ! medium-chain fatty acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:32362 ! is protonated form of heptanoate

[Term]
id: CHEBI:45599
name: dodecyl hydrogen sulfate
synonym: "DODECYL SULFATE" EXACT [PDBeChem]
is_a: CHEBI:29281 ! alkyl sulfate
relationship: RO:0018034 CHEBI:23872 ! is protonated form of dodecyl sulfate

[Term]
id: CHEBI:456216
name: ADP(3-)
def: "A nucleoside 5'-diphosphate(3−) arising from deprotonation of all three diphosphate OH groups of adenosine 5'-diphosphate (ADP); major species present at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:57930 ! nucleoside 5'-diphosphate(3-)
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:87518 ! is deprotonated form of ADP(2-)

[Term]
id: CHEBI:45630
name: 4-oxopentanoic acid
def: "An oxopentanoic acid with the oxo group in the 4-position." []
is_a: CHEBI:25799 ! oxopentanoic acid
is_a: CHEBI:39418 ! straight-chain saturated fatty acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:39150 ! is protonated form of 4-oxopentanoate

[Term]
id: CHEBI:45696
name: hydrogensulfate
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: RO:0018033 CHEBI:26836 ! is deprotonated form of sulfuric acid
relationship: RO:0018034 CHEBI:16189 ! is protonated form of sulfate

[Term]
id: CHEBI:45716
name: vorinostat
def: "A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and  hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13248 ! anilide
is_a: CHEBI:24650 ! hydroxamic acid
is_a: CHEBI:35779 ! dicarboxylic acid diamide
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:15429 ! has functional parent hydroxylamine
relationship: RO:0018038 CHEBI:9300 ! has functional parent suberic acid

[Term]
id: CHEBI:45725
name: spermine(4+)
def: "An ammonium ion obtained by the protonation of all four amino groups of spermine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:15746 ! is protonated form of spermine

[Term]
id: CHEBI:45863
name: paclitaxel
def: "A tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, <em>Taxus brevifolia</em>. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50367 ! taxane diterpenoid
is_a: CHEBI:52557 ! tetracyclic diterpenoid
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:61950 ! has role microtubule-stabilising agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018038 CHEBI:32898 ! has functional parent baccatin III

[Term]
id: CHEBI:45895
name: tert-butanol
def: "A tertiary alcohol alcohol that is isobutane substituted by a hydroxy group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26878 ! tertiary alcohol
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018040 CHEBI:30363 ! has parent hydride isobutane

[Term]
id: CHEBI:45906
name: suramin
def: "A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134043 ! phenylureas
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:36336 ! naphthalenesulfonic acid
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36335 ! has role trypanocidal drug
relationship: RO:0000087 CHEBI:37700 ! has role EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0000087 CHEBI:38999 ! has role GABA-gated chloride channel antagonist
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:65259 ! has role GABA antagonist
relationship: RO:0000087 CHEBI:67114 ! has role ryanodine receptor agonist
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:91079 ! has role purinergic receptor P2 antagonist
relationship: RO:0018034 CHEBI:180911 ! is protonated form of suramin(6-)
relationship: RO:0018038 CHEBI:36334 ! has functional parent naphthalene-1,3,5-trisulfonic acid

[Term]
id: CHEBI:45924
name: trimethoprim
def: "An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge." []
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:51683 ! methoxybenzenes
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35498 ! has role diuretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50683 ! has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:45979
name: thiabendazole
def: "A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including <em>Aspergillus, Botrytis, Cladosporium</em> and <em>Fusarium</em>." []
synonym: "2-(1,3-THIAZOL-4-YL)-1H-BENZIMIDAZOLE" EXACT [PDBeChem]
is_a: CHEBI:38418 ! 1,3-thiazoles
is_a: CHEBI:87036 ! benzimidazole fungicide
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018040 CHEBI:41275 ! has parent hydride 1H-benzimidazole

[Term]
id: CHEBI:45993
name: benzothiazole
def: "An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37947 ! benzothiazoles
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:46024
name: trichostatin A
is_a: CHEBI:24650 ! hydroxamic acid
is_a: CHEBI:39146 ! trichostatin
is_a: CHEBI:86478 ! antibiotic antifungal agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018038 CHEBI:39158 ! has functional parent (R)-trichostatic acid

[Term]
id: CHEBI:46053
name: 2,4,6-trinitrotoluene
def: "A trinitrotoluene having the nitro groups at positions 2, 4 and 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27135 ! trinitrotoluene
relationship: RO:0000087 CHEBI:63490 ! has role explosive
relationship: RO:0018038 CHEBI:48113 ! has functional parent 1,3,5-trinitrobenzene

[Term]
id: CHEBI:46077
name: 4H-1,2,4-triazole
synonym: "1,2,4-TRIAZOLE" EXACT [PDBeChem]
is_a: CHEBI:35560 ! 1,2,4-triazole
relationship: RO:0018036 CHEBI:35550 ! is tautomer of 1H-1,2,4-triazole
relationship: RO:0018036 CHEBI:35561 ! is tautomer of 3H-1,2,4-triazole

[Term]
id: CHEBI:46081
name: fluconazole
def: "A member of the class of  triazoles that is propan-2-ol substituted at position 1 and 3 by 1<em>H</em>-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:38582 ! difluorobenzene
is_a: CHEBI:87071 ! conazole antifungal drug
is_a: CHEBI:87101 ! triazole antifungal drug
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50183 ! has role P450 inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38584 ! has functional parent 1,3-difluorobenzene
relationship: RO:0018040 CHEBI:35550 ! has parent hydride 1H-1,2,4-triazole

[Term]
id: CHEBI:4609
name: Dimethyl phthalate
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:35484 ! phthalate ester
is_a: CHEBI:36054 ! benzoate ester
is_a: CHEBI:51307 ! diester
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent

[Term]
id: CHEBI:46149
name: picric acid
def: "A <em>C</em>-nitro compound comprising phenol having three nitro substtituents at the 2-, 4- and 6-positions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25562 ! nitrophenol
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:50913 ! has role fixative
relationship: RO:0000087 CHEBI:63490 ! has role explosive
relationship: RO:0018034 CHEBI:86297 ! is protonated form of picrate anion
relationship: RO:0018038 CHEBI:15882 ! has functional parent phenol
relationship: RO:0018038 CHEBI:48113 ! has functional parent 1,3,5-trinitrobenzene

[Term]
id: CHEBI:46195
name: paracetamol
def: "A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:13248 ! anilide
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50629 ! has role cyclooxygenase 2 inhibitor
relationship: RO:0000087 CHEBI:50630 ! has role cyclooxygenase 1 inhibitor
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:73263 ! has role cyclooxygenase 3 inhibitor
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018038 CHEBI:17602 ! has functional parent 4-aminophenol

[Term]
id: CHEBI:46209
name: L-tyrosinal
def: "An amino aldehyde that is <small>L</small>-tyrosine in which the carboxy group has undergone formal redution to give the corrresponding aldehyde" []
is_a: CHEBI:22492 ! amino aldehyde
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0018033 CHEBI:141668 ! is deprotonated form of L-tyrosinal(1+)

[Term]
id: CHEBI:46245
name: coenzyme Q10
def: "A ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the <i>E</i>- configuration." []
is_a: CHEBI:16389 ! ubiquinones
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:46261
name: N-phenylthiourea
def: "A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in <em>N</em>-phenylthiourea being used in paternity testing prior to the advent of DNA testing." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51276 ! thioureas
relationship: RO:0000087 CHEBI:59997 ! has role EC 1.14.18.1 (tyrosinase) inhibitor
relationship: RO:0018038 CHEBI:36946 ! has functional parent thiourea

[Term]
id: CHEBI:4629
name: diosgenin
def: "A  sapogenin that is spirostan which is substituted by a hydroxy group at the 3β position, contains a double bond at the 5-6 position, and has <i>R</i>- configuration at position 25. A natural product found in <em>Dioscorea</em> (wild yam) species, it is used as the starting point for the commercial synthesis of a number of steroids, including cortisone, pregnenolone and progesterone." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26606 ! sapogenin
is_a: CHEBI:35348 ! 3beta-sterol
is_a: CHEBI:70994 ! hexacyclic triterpenoid
is_a: CHEBI:72600 ! spiroketal
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0018040 CHEBI:26745 ! has parent hydride spirostan

[Term]
id: CHEBI:46342
name: undecane
def: "A straight-chain alkane with 11 carbon atoms." []
synonym: "UNDECANE" EXACT [PDBeChem]
is_a: CHEBI:18310 ! alkane

[Term]
id: CHEBI:46345
name: 5-fluorouracil
def: "A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth." []
synonym: "5-Fluorouracil" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:67142 ! nucleobase analogue
relationship: RO:0000087 CHEBI:132992 ! has role radiosensitizing agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:17568 ! has functional parent uracil

[Term]
id: CHEBI:4638
name: diphenidol
def: "A tertiary alcohol that is butan-1-ol substituted by two phenyl groups at position 1 and a piperidin-1-yl group at position 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:51614 ! diarylmethane
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic

[Term]
id: CHEBI:4640
name: diphenylamine
def: "An aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union." []
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:87039 ! bridged diphenyl fungicide
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:72773 ! has role carotogenesis inhibitor
relationship: RO:0000087 CHEBI:72774 ! has role EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:46416
name: virginiamycin S1
def: "A cyclodepsipeptide that is <em>N</em>-(3-hydroxypicolinoyl)-<small>L</small>-threonyl-<small>D</small>-α-aminobutyryl-<small>L</small>-prolyl-<em>N</em>-methyl-<small>L</small>-phenylalanyl-4-oxo-<small>L</small>-pipecoloyl-<small>L</small>-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the <em>N</em>-(3-hydroxypicolinoyl)-<small>L</small>-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by <em>Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus,</em> and others." []
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:35213 ! cyclodepsipeptide
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:46430
name: (S,S,S)-alpha-tocopherol
def: "The (<i>S</i>,<i>S</i>,<i>S</i>)-stereoisomer of α-tocopherol." []
is_a: CHEBI:22470 ! alpha-tocopherol
relationship: RO:0018039 CHEBI:18145 ! is enantiomer of (R,R,R)-alpha-tocopherol

[Term]
id: CHEBI:46442
name: vanadate(3-)
def: "A vanadium oxoanion that is a trianion with formula VO<small><sub>4</sub></small> in which the vanadium is in the +5 oxidation state and is attached to four oxygen atoms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:30528 ! vanadium oxoanion
is_a: CHEBI:79387 ! trivalent inorganic anion
relationship: RO:0000087 CHEBI:35608 ! has role EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
relationship: RO:0000087 CHEBI:37153 ! has role EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
relationship: RO:0000087 CHEBI:63332 ! has role EC 3.1.3.1 (alkaline phosphatase) inhibitor
relationship: RO:0000087 CHEBI:77024 ! has role EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor
relationship: RO:0018033 CHEBI:35168 ! is deprotonated form of hydrogenvanadate

[Term]
id: CHEBI:46577
name: dextrofloxacin
def: "The (<i>R</i>)-enantiomer of ofloxacin." []
is_a: CHEBI:194135 ! 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
is_a: CHEBI:86324 ! quinolone antibiotic
is_a: CHEBI:87211 ! fluoroquinolone antibiotic
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:53559 ! has role topoisomerase IV inhibitor
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0018039 CHEBI:63598 ! is enantiomer of levofloxacin

[Term]
id: CHEBI:4659
name: disulfiram
def: "An organic disulfide that results from the formal oxidative dimerisation of <em>N</em>,<em>N</em>-diethyldithiocarbamic acid.  A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties." []
is_a: CHEBI:35489 ! organic disulfide
is_a: CHEBI:39298 ! organosulfur acaricide
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:35487 ! has role EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:50276 ! has role EC 5.99.1.2 (DNA topoisomerase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:73240 ! has role NF-kappaB inhibitor
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78444 ! has role EC 3.1.1.1 (carboxylesterase) inhibitor

[Term]
id: CHEBI:46629
name: oxo group
is_a: CHEBI:33246 ! inorganic group

[Term]
id: CHEBI:46630
name: 2,6-dichloroaniline
is_a: CHEBI:23696 ! dichloroaniline

[Term]
id: CHEBI:46631
name: clonidine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:24436 ! guanidines
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35569 ! has role alpha-adrenergic agonist
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:66991 ! has role sympatholytic agent
relationship: RO:0018038 CHEBI:46630 ! has functional parent 2,6-dichloroaniline

[Term]
id: CHEBI:46633
name: carbapenems
def: "The class of β-lactam antibiotics that whose members have a carbapenem skeleton which is variously substituted at positions 3, 4, and 6." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:27933 ! beta-lactam antibiotic
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent

[Term]
id: CHEBI:46634
name: carbapenemcarboxylic acid
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:46633 ! carbapenems

[Term]
id: CHEBI:46640
name: diketone
def: "A compound that contains two ketone functionalities." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:46645
name: isobutanol
def: "An alkyl alcohol that is propan-1-ol substituted by a methyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:50584 ! alkyl alcohol
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018040 CHEBI:30363 ! has parent hydride isobutane

[Term]
id: CHEBI:46648
name: nitrite salt
is_a: CHEBI:25549 ! nitrites
relationship: BFO:0000051 CHEBI:16301 ! has part nitrite

[Term]
id: CHEBI:46661
name: asbestos
def: "Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements." []
is_a: CHEBI:46663 ! silicate mineral

[Term]
id: CHEBI:46662
name: mineral
def: "In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals')." []
is_a: CHEBI:59999 ! chemical substance

[Term]
id: CHEBI:46663
name: silicate mineral
is_a: CHEBI:46662 ! mineral

[Term]
id: CHEBI:46668
name: amino-acid ester
def: "Any  carboxylic ester derivative of an amino acid." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:4667
name: valproate semisodium
def: "A mixture of valproic acid and its sodium salt in a 1:1 molar ratio. It is used for the management and treatment of seizure disorders, mania, and prophylactic treatment of migraine headache." []
is_a: CHEBI:35692 ! dicarboxylic acid
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:39867 ! has part valproic acid
relationship: BFO:0000051 CHEBI:9925 ! has part sodium valproate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35477 ! has role antimanic drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:51374 ! has role GABA agent

[Term]
id: CHEBI:46686
name: azaalkane
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:46687
name: diazaalkane
is_a: CHEBI:39474 ! polyazaalkane

[Term]
id: CHEBI:46690
name: reserpic acid
is_a: CHEBI:27358 ! yohimban alkaloid

[Term]
id: CHEBI:46691
name: 2,3-dihydroxy-5-methyl-1,4-benzoquinone
is_a: CHEBI:132124 ! 1,4-benzoquinones
relationship: RO:0018038 CHEBI:81667 ! has functional parent 2-hydroxy-5-methylquinone

[Term]
id: CHEBI:46695
name: fluorohydrocarbon
def: "A compound derived from a hydrocarbon by replacing one or more hydrogen atoms with fluorine atoms." []
is_a: CHEBI:24472 ! halohydrocarbon
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:46699
name: pyrazolopyridine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:46700
name: benzoxazole
def: "Compounds based on a fused 1,2- or 1,3-oxazole and benzene bicyclic ring skeleton." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:46701
name: pyrrolidinemonocarboxylic acid
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:46767 ! pyrrolidinecarboxylic acid

[Term]
id: CHEBI:4672
name: docetaxel anhydrous
def: "A tetracyclic diterpenoid that is paclitaxel with the <em>N</em>-benzyloxycarbonyl group replaced by <em>N</em>-<em>tert</em>-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:2468 ! secondary alpha-hydroxy ketone
is_a: CHEBI:52557 ! tetracyclic diterpenoid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent
relationship: RO:0018040 CHEBI:36064 ! has parent hydride taxane

[Term]
id: CHEBI:46721
name: carbonate salt
is_a: CHEBI:23016 ! carbonates
relationship: BFO:0000051 CHEBI:41609 ! has part carbonate

[Term]
id: CHEBI:46725
name: oxide mineral
is_a: CHEBI:24836 ! inorganic oxide
is_a: CHEBI:46662 ! mineral

[Term]
id: CHEBI:46733
name: oxabicycloalkane
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:46761
name: dipeptide
def: "Any molecule that contains two amino-acid residues connected by peptide linkages." []
is_a: CHEBI:25676 ! oligopeptide
relationship: RO:0018036 CHEBI:90799 ! is tautomer of dipeptide zwitterion

[Term]
id: CHEBI:46766
name: N-acylpyrrolidine
is_a: CHEBI:32988 ! amide
is_a: CHEBI:38260 ! pyrrolidines

[Term]
id: CHEBI:46767
name: pyrrolidinecarboxylic acid
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:38260 ! pyrrolidines

[Term]
id: CHEBI:46770
name: pyrrolidinecarboxamide
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:38260 ! pyrrolidines

[Term]
id: CHEBI:46771
name: pyrrolopyridine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:46774
name: polyether
def: "Any ether that contains more than one ether linkage." []
is_a: CHEBI:25698 ! ether

[Term]
id: CHEBI:46775
name: N-alkylpyrrolidine
is_a: CHEBI:38260 ! pyrrolidines
is_a: CHEBI:50996 ! tertiary amino compound

[Term]
id: CHEBI:46784
name: diglyme
def: "A polyether that is the dimethyl ether derivative of diethylene glycol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:46774 ! polyether
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:46787 ! has role solvent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:46807 ! has functional parent diethylene glycol

[Term]
id: CHEBI:46786
name: diether
def: "A polyether in which the number of ether linkages is 2." []
is_a: CHEBI:46774 ! polyether

[Term]
id: CHEBI:46787
name: solvent
def: "A substance that dissolves other substances (solutes) to form a solution without any change in their chemical composition." []
is_a: CHEBI:33232 ! application
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:46788
name: 2-ethoxyethanol
def: "A  hydroxyether that is the  ethyl ether derivative of ethylene glycol." []
synonym: "2-ETHOXYETHANOL" EXACT [PDBeChem]
synonym: "2-Ethoxyethanol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:172390 ! glycol ether
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0018038 CHEBI:30742 ! has functional parent ethylene glycol

[Term]
id: CHEBI:46789
name: hydroxyether
def: "Any ether carrying a hydroxy group at unspecified position." []
is_a: CHEBI:25698 ! ether
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:46790
name: 2-methoxyethanol
def: "A hydroxyether that is ethanol substituted by a methoxy group at position 2." []
synonym: "2-METHOXYETHANOL" EXACT [PDBeChem]
is_a: CHEBI:172390 ! glycol ether

[Term]
id: CHEBI:46792
name: hydroxypolyether
def: "A hydroxyether compound containing more than one ether group." []
is_a: CHEBI:46774 ! polyether
is_a: CHEBI:46789 ! hydroxyether

[Term]
id: CHEBI:46793
name: poly(ethylene glycol)
def: "A polymer composed of repeating ethyleneoxy units." []
is_a: CHEBI:46792 ! hydroxypolyether

[Term]
id: CHEBI:46800
name: ethanethioic O-acid
is_a: CHEBI:26952 ! thioacetic acid
relationship: RO:0018036 CHEBI:16555 ! is tautomer of ethanethioic S-acid

[Term]
id: CHEBI:46807
name: diethylene glycol
synonym: "2,2'-Oxydiethanol" EXACT [KEGG_COMPOUND]
is_a: CHEBI:46789 ! hydroxyether

[Term]
id: CHEBI:46812
name: 1,3-oxazoles
is_a: CHEBI:35790 ! oxazole

[Term]
id: CHEBI:46818
name: urate anion
def: "An organic anion obtained by removal of at least one proton from any uric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25696 ! organic anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:27226 ! is deprotonated form of uric acid

[Term]
id: CHEBI:46834
name: indacenes
def: "Molecular entities containing an indacene skeleton." []
is_a: CHEBI:38032 ! carbotricyclic compound

[Term]
id: CHEBI:46842
name: sarcosinium
def: "An α-amino-acid cation that is the conjugate acid of sarcosine, arising from protonation of the amino group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:15611 ! is protonated form of sarcosine

[Term]
id: CHEBI:46844
name: N-acylpiperazine
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:32988 ! amide

[Term]
id: CHEBI:46845
name: N-alkylpiperazine
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:50996 ! tertiary amino compound

[Term]
id: CHEBI:46847
name: N-iminopiperazine
is_a: CHEBI:26144 ! piperazines

[Term]
id: CHEBI:46848
name: N-arylpiperazine
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:50996 ! tertiary amino compound

[Term]
id: CHEBI:46850
name: organoammonium salt
is_a: CHEBI:35276 ! ammonium compound

[Term]
id: CHEBI:46851
name: N-(2-hydroxyethyl)piperazine
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:46845 ! N-alkylpiperazine

[Term]
id: CHEBI:46867
name: indolyl carboxylic acid
is_a: CHEBI:24828 ! indoles
is_a: CHEBI:33575 ! carboxylic acid

[Term]
id: CHEBI:46874
name: alpha-amino acid ester
def: "The amino acid ester derivative obtained the formal condensation of an α-amino acid with an alcohol." []
is_a: CHEBI:46668 ! amino-acid ester
relationship: RO:0018033 CHEBI:83410 ! is deprotonated form of alpha-amino acid ester(1+)
relationship: RO:0018038 CHEBI:33704 ! has functional parent alpha-amino acid

[Term]
id: CHEBI:46883
name: carboxy group
is_a: CHEBI:33249 ! organyl group

[Term]
id: CHEBI:46889
name: S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys
def: "A triacyl lipopeptide that is the pentapeptide Cys-Ser-Lys-Lys-Lys-Lys in which the side-chain thiol hydrogen on the Cys residue has been replaced by a 2,3-bis(palmitoyloxy)propyl group." []
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:46896 ! diacyl lipopeptide

[Term]
id: CHEBI:46895
name: lipopeptide
def: "A compound consisting of a peptide with attached lipid." []
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:18059 ! lipid

[Term]
id: CHEBI:46896
name: diacyl lipopeptide
is_a: CHEBI:46895 ! lipopeptide

[Term]
id: CHEBI:46899
name: benzothiazine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:46904
name: oxalate(1-)
def: "A dicarboxylic acid monoanion that is the conjugate base of oxalic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132952 ! oxalate
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:30623 ! is protonated form of oxalate(2-)

[Term]
id: CHEBI:46905
name: (R)-pantothenic acid
def: "A pantothenic acid having <i>R</i>-configuration." []
is_a: CHEBI:176840 ! vitamin B5
is_a: CHEBI:7916 ! pantothenic acid
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:74530 ! has role antidote to curare poisoning
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018034 CHEBI:29032 ! is protonated form of (R)-pantothenate

[Term]
id: CHEBI:46911
name: L-ornithinium(1+)
def: "A polar amino acid zwitterion of <small>L</small>-ornithine." []
is_a: CHEBI:46912 ! ornithinium(1+)
is_a: CHEBI:62031 ! polar amino acid zwitterion
relationship: RO:0018033 CHEBI:44667 ! is deprotonated form of L-ornithinium(2+)
relationship: RO:0018034 CHEBI:15729 ! is protonated form of L-ornithine

[Term]
id: CHEBI:46912
name: ornithinium(1+)
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:46913 ! is deprotonated form of ornithinium(2+)
relationship: RO:0018034 CHEBI:18257 ! is protonated form of ornithine

[Term]
id: CHEBI:46913
name: ornithinium(2+)
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:46912 ! is protonated form of ornithinium(1+)

[Term]
id: CHEBI:46914
name: L-ornithinate
def: "An <small>L</small>-α-amino acid anion that is the conjugate base of <small>L</small>-ornithine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32964 ! ornithinate
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15729 ! is deprotonated form of L-ornithine

[Term]
id: CHEBI:46915
name: sarcosinate
def: "An α-amino-acid anion that is the conjugate base of sarcosine, arising from deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15611 ! is deprotonated form of sarcosine

[Term]
id: CHEBI:46916
name: vinyl acetate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:747341 ! has role impact modifier

[Term]
id: CHEBI:46920
name: N-methylpiperazine
is_a: CHEBI:46845 ! N-alkylpiperazine

[Term]
id: CHEBI:46923
name: dioxane
def: "Any member of the class of dioxanes that is a cyclohexane in which two carbon atoms are replaced by oxygen atoms." []
is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent
is_a: CHEBI:46926 ! dioxanes

[Term]
id: CHEBI:46926
name: dioxanes
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:46931
name: capsaicinoid
def: "A family of aromatic fatty amides produced as secondary metabolites by chilli peppers." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29348 ! fatty amide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:46932
name: dihydrocapsaicin
is_a: CHEBI:46931 ! capsaicinoid

[Term]
id: CHEBI:46938
name: zebularine
is_a: CHEBI:39446 ! pyrimidine ribonucleosides

[Term]
id: CHEBI:46940
name: indanes
is_a: CHEBI:36785 ! carbobicyclic compound

[Term]
id: CHEBI:46942
name: oxanes
def: "Any organic heteromonocyclic compoundthat is oxane or its substituted derivatives." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:46945
name: N-acyldiazepane
is_a: CHEBI:32988 ! amide
is_a: CHEBI:38823 ! diazepane

[Term]
id: CHEBI:46946
name: N-sulfonyldiazepane
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:46945 ! N-acyldiazepane

[Term]
id: CHEBI:46952
name: oxazinane
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:46955
name: anthracenes
def: "Compounds containing an anthracene skeleton." []
is_a: CHEBI:38032 ! carbotricyclic compound
is_a: CHEBI:51269 ! acenes

[Term]
id: CHEBI:46961
name: phytosphingosine
is_a: CHEBI:22478 ! amino alcohol
is_a: CHEBI:27136 ! triol
is_a: CHEBI:35785 ! sphingoid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:64124 ! is deprotonated form of phytosphingosine(1+)
relationship: RO:0018038 CHEBI:157775 ! has functional parent N-acyl-beta-D-galactosylphytosphingosine
relationship: RO:0018038 CHEBI:16566 ! has functional parent sphinganine

[Term]
id: CHEBI:46963
name: 2-aminooctadecene-1,3-diol
def: "An aminodiol composed of any octadecene having hydroxy functional groups at positions 1 and 3 and an amino substituent at position 2." []
is_a: CHEBI:22501 ! aminodiol
is_a: CHEBI:35785 ! sphingoid

[Term]
id: CHEBI:46964
name: 2-aminooctadec-4-ene-1,3-diol
def: "A 2-aminooctadecene-1,3-diol having its double bond at position 4." []
is_a: CHEBI:46963 ! 2-aminooctadecene-1,3-diol

[Term]
id: CHEBI:46965
name: (2R,3S)-2-aminooctadec-4-ene-1,3-diol
def: "A 2-aminooctadec-4-ene-1,3-diol having (2<i>R</i>,3<i>S</i>)-configuration." []
is_a: CHEBI:46964 ! 2-aminooctadec-4-ene-1,3-diol
relationship: RO:0018039 CHEBI:26743 ! is enantiomer of sphing-4-enine

[Term]
id: CHEBI:46967
name: L-erythro-sphingosine
def: "A (2<i>R</i>,3<i>S</i>)-2-aminooctadec-4-ene-1,3-diol in which the double bond has <i>E</i> geochemistry." []
is_a: CHEBI:46965 ! (2R,3S)-2-aminooctadec-4-ene-1,3-diol
relationship: RO:0018033 CHEBI:77956 ! is deprotonated form of L-erythro-sphingosine(1+)
relationship: RO:0018039 CHEBI:16393 ! is enantiomer of sphingosine

[Term]
id: CHEBI:46968
name: 2-aminooctadecane-1,3-diol
def: "An aminodiol that is octadecane bearing two hydroxy substituents at positions 1 and 3 as well as an amino substituent at position 2." []
is_a: CHEBI:22501 ! aminodiol
is_a: CHEBI:35785 ! sphingoid

[Term]
id: CHEBI:46969
name: benzoxazine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:46986
name: azepanes
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:46997
name: L-ribose
def: "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in <small>L</small>-glyceraldehyde." []
is_a: CHEBI:33942 ! ribose
relationship: RO:0018039 CHEBI:16988 ! is enantiomer of D-ribose

[Term]
id: CHEBI:46998
name: ribofuranose
def: "A cyclic ribose having a 5-membered tetrahydrofuran ring; the predominant (C3'-endo) form of the two cyclic structures (the other is the \"C2'-endo\" form, having a 6-membered ring) adopted by ribose in aqueous solution." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33942 ! ribose
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite

[Term]
id: CHEBI:47000
name: L-ribofuranose
def: "An ribofuranose having <small>L</small>-configuration." []
is_a: CHEBI:46997 ! L-ribose
is_a: CHEBI:46998 ! ribofuranose

[Term]
id: CHEBI:47002
name: beta-D-ribose
def: "A <small>D</small>-ribofuranose in which the anomeric centre has β-configuration." []
is_a: CHEBI:47013 ! D-ribofuranose
relationship: RO:0018039 CHEBI:47005 ! is enantiomer of beta-L-ribose

[Term]
id: CHEBI:47005
name: beta-L-ribose
is_a: CHEBI:47000 ! L-ribofuranose
relationship: RO:0018039 CHEBI:47002 ! is enantiomer of beta-D-ribose

[Term]
id: CHEBI:47013
name: D-ribofuranose
def: "A ribofuranose having <small>D</small>-configuration." []
synonym: "D-Ribose" EXACT [KEGG_COMPOUND]
is_a: CHEBI:16988 ! D-ribose
is_a: CHEBI:46998 ! ribofuranose

[Term]
id: CHEBI:47016
name: tetrahydrofuranone
def: "Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring." []
is_a: CHEBI:26912 ! oxolanes

[Term]
id: CHEBI:47017
name: tetrahydrofuranol
is_a: CHEBI:26912 ! oxolanes

[Term]
id: CHEBI:47018
name: monohydroxytetrahydrofuran
is_a: CHEBI:47017 ! tetrahydrofuranol

[Term]
id: CHEBI:47019
name: dihydroxytetrahydrofuran
is_a: CHEBI:47017 ! tetrahydrofuranol

[Term]
id: CHEBI:47026
name: diselenide
def: "Compounds having the structure RSe<small><sub>2</sub></small>R, with R ≠ H." []
is_a: CHEBI:26628 ! selenium molecular entity

[Term]
id: CHEBI:47032
name: 1,4-dioxane
def: "A dioxane with oxygen atoms at positions 1 and 4." []
synonym: "1,4-Dioxane" EXACT [KEGG_COMPOUND]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:46923 ! dioxane
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:4705
name: double-stranded DNA
is_a: CHEBI:16991 ! deoxyribonucleic acid

[Term]
id: CHEBI:47077
name: dibromomethane
def: "A member of the class of  bromomethanes that is methane substituted by two bromo groups. It is produced by marine algae." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:39278 ! bromomethanes
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite

[Term]
id: CHEBI:47136
name: pentachlorobenzene
def: "A member of the class of pentachlorobenzenes that is benzene in which five of the hydrogens are replaced by chlorines. Now classed as a persistent organic pollutant under the Stockholm Convention." []
synonym: "1,2,3,4,5-PENTACHLOROBENZENE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:83390 ! pentachlorobenzenes
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:47217
name: arsane
synonym: "arsine" EXACT [NIST_Chemistry_WebBook]
is_a: CHEBI:22637 ! arsine
is_a: CHEBI:35823 ! arsanes
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0018033 CHEBI:30272 ! is deprotonated form of arsonium
relationship: RO:0018034 CHEBI:29755 ! is protonated form of arsanide

[Term]
id: CHEBI:472552
name: 5-bromo-2'-deoxyuridine
def: "A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:47266
name: hydrogen bromide
def: "A diatomic molecule containing covalently bonded hydrogen and bromine atoms." []
synonym: "hydrogen bromide" EXACT [NIST_Chemistry_WebBook]
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:18140 ! hydrogen halide
is_a: CHEBI:37176 ! mononuclear parent hydride
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0018033 CHEBI:50316 ! is deprotonated form of bromonium
relationship: RO:0018034 CHEBI:15858 ! is protonated form of bromide

[Term]
id: CHEBI:47319
name: chlorimuron-ethyl
def: "An ethyl ester resulting from the formal condensation of the carboxy group of chlorimuron with ethanol. A proherbicide for chloimuron, it is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops." []
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38656 ! organochlorine pesticide
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:48471 ! sulfamoylbenzoate
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:136646 ! has role proherbicide
relationship: RO:0000087 CHEBI:22180 ! has role EC 2.2.1.6 (acetolactate synthase) inhibitor
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0018034 CHEBI:188144 ! is protonated form of chlorimuron-ethyl(1-)
relationship: RO:0018038 CHEBI:81953 ! has functional parent chlorimuron

[Term]
id: CHEBI:4735
name: ethylenediaminetetraacetic acid
is_a: CHEBI:31577 ! ethylenediamine derivative
is_a: CHEBI:35742 ! tetracarboxylic acid
is_a: CHEBI:60892 ! polyamino carboxylic acid
relationship: RO:0000087 CHEBI:166831 ! has role copper chelator
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:232436 ! has role calcium chelator
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0018034 CHEBI:64755 ! is protonated form of EDTA(2-)
relationship: RO:0018038 CHEBI:35742 ! has functional parent tetracarboxylic acid

[Term]
id: CHEBI:4738
name: EPTC
is_a: CHEBI:32876 ! tertiary amine

[Term]
id: CHEBI:47381
name: diclofenac
def: "A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33709 ! amino acid
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35544 ! has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:48311 ! is protonated form of diclofenac(1-)
relationship: RO:0018038 CHEBI:30745 ! has functional parent phenylacetic acid
relationship: RO:0018038 CHEBI:4640 ! has functional parent diphenylamine

[Term]
id: CHEBI:473990
name: entecavir (anhydrous)
def: "Guanine substituted at the 9 position by a 4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl group. A synthetic analogue of 2'-deoxyguanosine, it is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus. Entecavir is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it has no activity against HIV. It is used for the treatment of chronic hepatitis B." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:20702 ! 2-aminopurines
is_a: CHEBI:25810 ! oxopurine
is_a: CHEBI:26394 ! purine nucleoside
is_a: CHEBI:35681 ! secondary alcohol
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:59897 ! has role EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor

[Term]
id: CHEBI:473992
name: nystatin A1
def: "A polyene macrolide antibiotic; part of the nystatin complex produced by several <em>Streptomyces</em> species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species." []
is_a: CHEBI:59676 ! nystatins

[Term]
id: CHEBI:474180
name: caspofungin
def: "A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-β-<small>D</small>-glucan, an integral component of the fungal cell wall." []
is_a: CHEBI:24613 ! homodetic cyclic peptide
is_a: CHEBI:57248 ! echinocandin
is_a: CHEBI:72588 ! semisynthetic derivative
is_a: CHEBI:87113 ! antibiotic antifungal drug
relationship: RO:0018038 CHEBI:131609 ! has functional parent pneumocandin B0

[Term]
id: CHEBI:47426
name: furosemide
def: "A  chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure." []
is_a: CHEBI:23134 ! chlorobenzoic acid
is_a: CHEBI:24129 ! furans
is_a: CHEBI:35358 ! sulfonamide
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77608 ! has role loop diuretic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:474859
name: maleic anhydride
def: "A cyclic dicarboxylic anhydride that is the cyclic anhydride of maleic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24129 ! furans
is_a: CHEBI:36609 ! cyclic dicarboxylic anhydride
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:47499
name: imipramine
def: "A dibenzoazepine that is 5<em>H</em>-dibenzo[<em>b</em>,<em>f</em>]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47804 ! dibenzoazepine
is_a: CHEBI:53802 ! dibenzooxazepine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0018040 CHEBI:47802 ! has parent hydride 5H-dibenzo[b,f]azepine

[Term]
id: CHEBI:47518
name: (2S,4R)-ketoconazole
def: "A <i>cis</i>-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1<em>H</em>-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2<i>S</i>,4<i>R</i>)-configuration." []
is_a: CHEBI:86411 ! cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0018039 CHEBI:48336 ! is enantiomer of (2R,4S)-ketoconazole

[Term]
id: CHEBI:47519
name: ketoconazole
def: "A racemate consisting of equimolar amounts of (2<i>R</i>,4<i>S</i>)- and (2<i>S</i>,4<i>R</i>)-ketoconazole." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87069 ! imidazole antifungal drug
is_a: CHEBI:87071 ! conazole antifungal drug
relationship: BFO:0000051 CHEBI:47518 ! has part (2S,4R)-ketoconazole
relationship: BFO:0000051 CHEBI:48336 ! has part (2R,4S)-ketoconazole
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent

[Term]
id: CHEBI:47553
name: 2-chloroethyl group
is_a: CHEBI:50491 ! haloalkyl group
relationship: RO:0018037 CHEBI:47554 ! is substitutent group from chloroethane

[Term]
id: CHEBI:47554
name: chloroethane
def: "The simplest and least toxic member of the class of chloroethanes, that is ethane in which a single hydrogen is substituted by a chlorine. A colourless gas at room temperature and pressure (boiling point 12°C), it is used as a mild topical anaesthetic to numb the skin prior to ear piercing, skin biopsies, etc., and is also used in the treatment of sports injuries. It was formerly used in the production of tetraethyllead." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36016 ! chloroethanes
relationship: RO:0000087 CHEBI:36333 ! has role local anaesthetic
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0000087 CHEBI:59683 ! has role antipruritic drug

[Term]
id: CHEBI:4757
name: EDTA monocalcium diisodium salt
def: "An organic calcium salt of EDTA diisodium. It is a chelating agent that is used for the treatment of lead poisoning." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:51031 ! organic calcium salt
relationship: BFO:0000051 CHEBI:64734 ! has part EDTA disodium salt (anhydrous)
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38161 ! has role chelator
relationship: RO:0000087 CHEBI:50247 ! has role antidote

[Term]
id: CHEBI:47600
name: purvalanol A
is_a: CHEBI:38934 ! purvalanol

[Term]
id: CHEBI:47612
name: bezafibrate
def: "A monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:4762
name: eflornithine hydrochloride monohydrate
def: "The hydrochloride and hydrate of the  trypanocidal drug eflornithine." []
is_a: CHEBI:35505 ! hydrate
is_a: CHEBI:36807 ! hydrochloride
relationship: BFO:0000051 CHEBI:41948 ! has part eflornithine

[Term]
id: CHEBI:47622
name: acetate ester
def: "Any carboxylic ester where the carboxylic acid component is acetic acid." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:47696
name: 2,4,6-tribromophenol
def: "A bromophenol that is phenol in which the hydrogens at positions 2, 4 and 6 have been replaced by bromines. It is commonly used as a fungicide and in the preparation of flame retardants." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33624 ! bromophenol
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:47697
name: 4,5,6,7-TETRABROMOBENZOTRIAZOLE
is_a: CHEBI:48912 ! benzotriazoles

[Term]
id: CHEBI:47704
name: ammonium salt
is_a: CHEBI:35276 ! ammonium compound
relationship: BFO:0000051 CHEBI:28938 ! has part ammonium

[Term]
id: CHEBI:47724
name: vancomycin aglycone
def: "A peptide antibiotic that is vancomycin lacking the disaccharide moiety." []
is_a: CHEBI:24533 ! heterodetic cyclic peptide
is_a: CHEBI:25903 ! peptide antibiotic
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:37407 ! cyclic ether
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018034 CHEBI:77981 ! is protonated form of vancomycin aglycone(1-)
relationship: RO:0018036 CHEBI:75954 ! is tautomer of vancomycin aglycone zwitterion

[Term]
id: CHEBI:4775
name: ellagic acid
def: "An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates." []
is_a: CHEBI:25000 ! lactone
is_a: CHEBI:26848 ! tannin
is_a: CHEBI:33566 ! catechols
is_a: CHEBI:38163 ! organic heterotetracyclic compound
is_a: CHEBI:3992 ! cyclic ketone
relationship: RO:0000087 CHEBI:131699 ! has role EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50276 ! has role EC 5.99.1.2 (DNA topoisomerase) inhibitor
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:59997 ! has role EC 1.14.18.1 (tyrosinase) inhibitor
relationship: RO:0000087 CHEBI:64047 ! has role food additive
relationship: RO:0000087 CHEBI:76797 ! has role EC 2.5.1.18 (glutathione transferase) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:84799 ! has role EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor
relationship: RO:0000087 CHEBI:84800 ! has role EC 2.4.1.1 (glycogen phosphorylase) inhibitor
relationship: RO:0000087 CHEBI:84801 ! has role EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor
relationship: RO:0000087 CHEBI:84802 ! has role EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor
relationship: RO:0000087 CHEBI:84804 ! has role EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor
relationship: RO:0000087 CHEBI:85046 ! has role skin lightening agent
relationship: RO:0018034 CHEBI:235343 ! is protonated form of ellagic acid(2-)
relationship: RO:0018038 CHEBI:30778 ! has functional parent gallic acid

[Term]
id: CHEBI:47774
name: low-density lipoprotein cholesterol
def: "Cholesterol esters and free cholesterol which are contained in or bound to low-density lipoproteins (LDL)." []
is_a: CHEBI:50404 ! lipoprotein cholesterol

[Term]
id: CHEBI:47775
name: high-density lipoprotein cholesterol
def: "Cholesterol esters and free cholesterol which are contained in or bound to high-density lipoproteins (HDL)." []
is_a: CHEBI:50404 ! lipoprotein cholesterol

[Term]
id: CHEBI:47778
name: glyceride
def: "Any ester resulting from the condensation of one or more of the hydroxy groups of glycerol (propane-1,2,3-triol) with fatty acids." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:35741 ! glycerolipid

[Term]
id: CHEBI:47779
name: aminoglycoside
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:47781
name: desipramine
def: "A dibenzoazepine consisting of 10,11-dihydro-5<em>H</em>-dibenzo[<em>b</em>,<em>f</em>]azepine substituted on nitrogen with a 3-(methylamino)propyl group." []
synonym: "3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE" EXACT [PDBeChem]
is_a: CHEBI:47804 ! dibenzoazepine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:53802 ! dibenzooxazepine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0000087 CHEBI:37955 ! has role H1-receptor antagonist
relationship: RO:0000087 CHEBI:48873 ! has role cholinergic antagonist
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0000087 CHEBI:76811 ! has role EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:47783
name: cyclopentafuran
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:47787
name: 11-oxo steroid
def: "Any oxo steroid that has an oxo substituent at position 11." []
is_a: CHEBI:35789 ! oxo steroid

[Term]
id: CHEBI:47788
name: 3-oxo steroid
def: "Any oxo steroid where an oxo substituent is located at position 3." []
is_a: CHEBI:35789 ! oxo steroid
is_a: CHEBI:3992 ! cyclic ketone

[Term]
id: CHEBI:47802
name: 5H-dibenzo[b,f]azepine
def: "A mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36416 ! mancude organic heterotricyclic parent
is_a: CHEBI:47804 ! dibenzoazepine
relationship: RO:0000087 CHEBI:83399 ! has role marine xenobiotic metabolite

[Term]
id: CHEBI:47804
name: dibenzoazepine
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:47807
name: sulforaphane
def: "An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22063 ! sulfoxide
is_a: CHEBI:52221 ! isothiocyanate
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:47811
name: penamcarboxylate
is_a: CHEBI:35757 ! monocarboxylic acid anion

[Term]
id: CHEBI:47814
name: tetrahydrofuryl ether
is_a: CHEBI:26912 ! oxolanes

[Term]
id: CHEBI:47835
name: levibuprofen
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:5855 ! ibuprofen
relationship: RO:0018039 CHEBI:43415 ! is enantiomer of dexibuprofen

[Term]
id: CHEBI:47856
name: citronellal
def: "A monoterpenoid, the main component of citronella oil which gives it its distinctive lemon aroma." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17478 ! aldehyde
is_a: CHEBI:25409 ! monoterpenoid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:47857
name: ureas
is_a: CHEBI:33256 ! primary amide
relationship: RO:0018038 CHEBI:16199 ! has functional parent urea

[Term]
id: CHEBI:47867
name: indicator
def: "Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:47868
name: photosensitizing agent
def: "A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:47869
name: thioglycolate(2-)
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:30066 ! is deprotonated form of thioglycolate(1-)

[Term]
id: CHEBI:47875
name: tetrabromomethane
def: "A one-carbon compound substituted by 4 bromo groups." []
is_a: CHEBI:39278 ! bromomethanes

[Term]
id: CHEBI:47880
name: steroid ester
is_a: CHEBI:35341 ! steroid
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:47881
name: 3-oxo monocarboxylic acid
is_a: CHEBI:35871 ! oxo monocarboxylic acid
relationship: RO:0018034 CHEBI:35973 ! is protonated form of 3-oxo monocarboxylic acid anion

[Term]
id: CHEBI:47882
name: cyclic polypyrrole
is_a: CHEBI:38077 ! polypyrrole

[Term]
id: CHEBI:47891
name: steroid acid
def: "Any steroid substituted by at least one carboxy group." []
is_a: CHEBI:35341 ! steroid
is_a: CHEBI:64709 ! organic acid
relationship: RO:0018034 CHEBI:50160 ! is protonated form of steroid acid anion

[Term]
id: CHEBI:47898
name: 4'-epidoxorubicin
def: "An anthracycline that is the 4'-epi-isomer of doxorubicin." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:25830 ! p-quinones
is_a: CHEBI:35315 ! deoxy hexoside
is_a: CHEBI:47779 ! aminoglycoside
is_a: CHEBI:49322 ! anthracycline antibiotic
is_a: CHEBI:63367 ! monosaccharide derivative
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0018033 CHEBI:41983 ! is deprotonated form of 4'-epidoxorubicinium
relationship: RO:0018038 CHEBI:28748 ! has functional parent doxorubicin

[Term]
id: CHEBI:47901
name: alkanesulfonic acid
def: "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group." []
is_a: CHEBI:33551 ! organosulfonic acid
relationship: BFO:0000051 CHEBI:22323 ! has part alkyl group

[Term]
id: CHEBI:47908
name: alkanethiol
def: "An alkanethiol is a compound in which a sulfanyl group, ‒SH, is attached to an alkyl group." []
is_a: CHEBI:29256 ! thiol

[Term]
id: CHEBI:47909
name: 3-oxo-Delta(4) steroid
def: "A 3-oxo steroid conjugated to a C=C double bond at the α,β position." []
is_a: CHEBI:47788 ! 3-oxo steroid
is_a: CHEBI:51689 ! enone
relationship: BFO:0000051 CHEBI:136849 ! has part 3-oxo-Delta(4)-steroid group

[Term]
id: CHEBI:4791
name: endosulfan
def: "A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10." []
is_a: CHEBI:23457 ! cyclodiene organochlorine insecticide
is_a: CHEBI:39089 ! cyclic sulfite ester
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:38999 ! has role GABA-gated chloride channel antagonist
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:47910
name: S-substituted L-cysteine
is_a: CHEBI:26834 ! sulfur-containing amino acid
is_a: CHEBI:83824 ! L-cysteine derivative
relationship: RO:0018036 CHEBI:58717 ! is tautomer of S-substituted L-cysteine zwitterion

[Term]
id: CHEBI:47916
name: flavonoid
def: "Any member of the 'superclass' flavonoids whose skeleton is based on 1-benzopyran with an aryl substituent at position 2. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds." []
is_a: CHEBI:72544 ! flavonoids
relationship: RO:0018034 CHEBI:60038 ! is protonated form of flavonoid oxoanion
relationship: RO:0018038 CHEBI:26004 ! has functional parent phenylpropanoid
relationship: RO:0018038 CHEBI:38443 ! has functional parent 1-benzopyran

[Term]
id: CHEBI:4792
name: enflurane
def: "An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:38867 ! has role anaesthetic
relationship: RO:0018038 CHEBI:39832 ! has functional parent methoxyethane

[Term]
id: CHEBI:47923
name: tripeptide
def: "Any oligopeptide that consists of three amino-acid residues connected by peptide linkages." []
is_a: CHEBI:25676 ! oligopeptide
relationship: RO:0018036 CHEBI:155837 ! is tautomer of tripeptide zwitterion

[Term]
id: CHEBI:47945
name: 2',3'-dideoxyribonucleoside
is_a: CHEBI:23636 ! deoxyribonucleoside

[Term]
id: CHEBI:47956
name: thiocarboxamide
def: "Any primary amide having its amide oxygen replaced by sulfur." []
is_a: CHEBI:33256 ! primary amide

[Term]
id: CHEBI:47958
name: nicotinic acetylcholine receptor agonist
def: "An agonist that selectively binds to and activates a nicotinic acetylcholine receptor." []
is_a: CHEBI:38324 ! cholinergic agonist

[Term]
id: CHEBI:47985
name: enol ether
def: "Ethers ROR' where R has a double bond adjacent to the oxygen of the ether linkage." []
is_a: CHEBI:25698 ! ether
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:47989
name: enamine
def: "An amine RNR'R'' where R has a double bond adjacent to the amine nitrogen." []
is_a: CHEBI:32952 ! amine
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:48001
name: protein synthesis inhibitor
def: "A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein." []
is_a: CHEBI:76932 ! pathway inhibitor

[Term]
id: CHEBI:48009
name: N-glycosyl-1,3,5-triazine
is_a: CHEBI:21731 ! N-glycosyl compound
is_a: CHEBI:26588 ! 1,3,5-triazines

[Term]
id: CHEBI:48024
name: 3'-hydroxyflavanones
def: "Any hydroxyflavanone with a hydroxy substituent at position 3' of the phenyl ring." []
is_a: CHEBI:24697 ! hydroxyflavanone

[Term]
id: CHEBI:48030
name: tetrapeptide
def: "Any molecule that contains four amino-acid residues connected by peptide linkages." []
is_a: CHEBI:25676 ! oligopeptide

[Term]
id: CHEBI:48041
name: microcystin
def: "A family of cyclic heptapeptide hepatotoxins produced by a number of cyanobacteria, the most notable of which is <em>Microcystis</em>, from which the name of the family is derived. Microcystins consist of a heptapeptide macrocycle made up of five non-protein amino acids and two protein amino acids." []
is_a: CHEBI:24533 ! heterodetic cyclic peptide
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:88048 ! has role cyanotoxin

[Term]
id: CHEBI:48080
name: brefeldin A
def: "A metabolite from <em>Penicillium brefeldianum</em> that exhibits a wide range of antibiotic activity." []
is_a: CHEBI:25105 ! macrolide antibiotic
relationship: RO:0000087 CHEBI:76964 ! has role Penicillium metabolite

[Term]
id: CHEBI:48081
name: bacteriocin
def: "Polypeptides synthesized by specific strains of bacteria that are lethal against other strains of the same or related species." []
is_a: CHEBI:25903 ! peptide antibiotic

[Term]
id: CHEBI:480999
name: vinorelbine
def: "A vinca alkaloid with a norvinblastine skeleton." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:27288 ! vinca alkaloid
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:38163 ! organic heterotetracyclic compound
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:47868 ! has role photosensitizing agent

[Term]
id: CHEBI:48107
name: nitric acid
def: "A nitrogen oxoacid of formula HNO<small><sub>3</sub></small> in which the nitrogen atom is bonded to a hydroxy group and by equivalent bonds to the remaining two oxygen atoms." []
is_a: CHEBI:33455 ! nitrogen oxoacid
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:51081 ! nitrates
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:48356 ! has role protic solvent
relationship: RO:0018034 CHEBI:17632 ! is protonated form of nitrate

[Term]
id: CHEBI:48109
name: nitrobenzenes
def: "A <em>C</em>-nitro compound with formula C<small><sub>6</sub></small>H<small><sub>(6−<em>n</em>)</sub></small>(NO<small><sub>2</sub></small>)<small><sub><em>n</em></sub></small> (<em>n</em> can be from 1 up to 6, but is usually 1, 2 or 3). A closed class." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:35716 ! C-nitro compound

[Term]
id: CHEBI:4811
name: epoxiconazole
def: "A racemate composed of equimolar amounts of (2<i>S</i>,3<i>R</i>)- and (2<i>R</i>,3<i>S</i>)-epoxiconazole. A broad-spectrum fungicide for control of diseases caused by <em>Ascomycetes</em>, <em>Basidiomycetes</em> and <em>Deuteromycetes</em>. Epoxiconazole is moderately toxic to birds, honeybees, earthworms and most aquatic organisms." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: BFO:0000051 CHEBI:83759 ! has part (2S,3R)-epoxiconazole
relationship: BFO:0000051 CHEBI:83761 ! has part (2R,3S)-epoxiconazole
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:48110
name: trinitrobenzene
is_a: CHEBI:48109 ! nitrobenzenes

[Term]
id: CHEBI:48113
name: 1,3,5-trinitrobenzene
def: "A trinitrobenzene in which each of the nitro groups is <em>meta</em>- to the other two." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48110 ! trinitrobenzene
relationship: RO:0000087 CHEBI:63490 ! has role explosive

[Term]
id: CHEBI:48117
name: 1-glycosylimidazole
is_a: CHEBI:21731 ! N-glycosyl compound
is_a: CHEBI:24780 ! imidazoles

[Term]
id: CHEBI:48120
name: anthracycline
def: "Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26188 ! polyketide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018033 CHEBI:64678 ! is deprotonated form of anthracycline cation

[Term]
id: CHEBI:48121
name: polyene
def: "An olefin that contains more than one carbon-carbon double bond." []
is_a: CHEBI:33641 ! olefin

[Term]
id: CHEBI:48123
name: silicate ion
is_a: CHEBI:37191 ! silicon oxoanion

[Term]
id: CHEBI:48132
name: tetracenomycin
def: "A polyketide based on a tetracene ring structure." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26188 ! polyketide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:4814
name: eprosartan
def: "A member of the class of  imidazoles and  thiophenes  that is an angiotensin II receptor antagonist used for the treatment of high blood pressure." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:26961 ! thiophenes
is_a: CHEBI:35692 ! dicarboxylic acid
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:61016 ! has role angiotensin receptor antagonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:48154
name: sulfur oxide
is_a: CHEBI:24836 ! inorganic oxide
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:48199
name: sulfamate ester
is_a: CHEBI:35701 ! ester
relationship: RO:0018038 CHEBI:9330 ! has functional parent sulfamic acid

[Term]
id: CHEBI:48210
name: cyclopentafurofurochromene
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:38164 ! organic heteropentacyclic compound

[Term]
id: CHEBI:48218
name: antiseptic drug
def: "A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body)." []
is_a: CHEBI:35441 ! antiinfective agent

[Term]
id: CHEBI:48219
name: disinfectant
def: "An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity." []
is_a: CHEBI:33281 ! antimicrobial agent

[Term]
id: CHEBI:48232
name: calcium oxides
is_a: CHEBI:22985 ! calcium molecular entity

[Term]
id: CHEBI:48235
name: chromium oxide
is_a: CHEBI:35403 ! chromium coordination entity

[Term]
id: CHEBI:48236
name: trichlorofluoromethane
def: "A one-carbon compound that is methane in which the hydrogens have been replaced by three chlorine and one fluorine atom." []
is_a: CHEBI:134024 ! chlorofluorocarbon
is_a: CHEBI:39279 ! halomethane
relationship: RO:0000087 CHEBI:197449 ! has role NMR solvent
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:48242
name: dichromium trioxide
is_a: CHEBI:48235 ! chromium oxide

[Term]
id: CHEBI:48277
name: triazolopyrazine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:48278
name: serotonergic drug
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:48279
name: serotonergic antagonist
def: "Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists." []
is_a: CHEBI:48278 ! serotonergic drug

[Term]
id: CHEBI:48294
name: N-methylserotonin
def: "A member of the class of tryptamines that is serotonin in which one of the hydrogens attached to the primary amino group is replaced by a methyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27162 ! tryptamines
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018038 CHEBI:28790 ! has functional parent serotonin

[Term]
id: CHEBI:48311
name: diclofenac(1-)
def: "The conjugate base of diclofenac." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:47381 ! is deprotonated form of diclofenac

[Term]
id: CHEBI:48318
name: fragrance
def: "A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:48336
name: (2R,4S)-ketoconazole
def: "A <i>cis</i>-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1<em>H</em>-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2<i>R</i>,4<i>S</i>)-configuration." []
is_a: CHEBI:86411 ! cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
relationship: RO:0018039 CHEBI:47518 ! is enantiomer of (2S,4R)-ketoconazole

[Term]
id: CHEBI:48339
name: 1-acetyl-4-(4-\{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy\}phenyl)piperazine
def: "A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [<em>para</em>-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:25698 ! ether
is_a: CHEBI:39430 ! dioxolane
is_a: CHEBI:46844 ! N-acylpiperazine
is_a: CHEBI:46848 ! N-arylpiperazine

[Term]
id: CHEBI:48341
name: dimethoxymethane
def: "An  acetal that is the dimethyl acetal derivative of formaldehyde." []
is_a: CHEBI:46786 ! diether
is_a: CHEBI:59769 ! acetal
relationship: RO:0018038 CHEBI:48397 ! has functional parent methanediol

[Term]
id: CHEBI:48343
name: disulfide
def: "Compounds of structure RSSR'." []
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:48347
name: triclocarban
def: "A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134043 ! phenylureas
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:41320 ! has functional parent 1,3-diphenylurea

[Term]
id: CHEBI:48353
name: serine proteinase inhibitor
def: "An exogenous or endogenous compound which inhibits serine endopeptidases." []
is_a: CHEBI:37670 ! protease inhibitor
is_a: CHEBI:5924 ! EC 3.4.21.* (serine endopeptidase) inhibitor

[Term]
id: CHEBI:48354
name: polar solvent
def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." []
is_a: CHEBI:46787 ! solvent

[Term]
id: CHEBI:48355
name: non-polar solvent
is_a: CHEBI:46787 ! solvent

[Term]
id: CHEBI:48356
name: protic solvent
def: "A polar solvent that is capable of acting as a hydron (proton) donor." []
is_a: CHEBI:39141 ! Bronsted acid
is_a: CHEBI:48354 ! polar solvent

[Term]
id: CHEBI:48357
name: aprotic solvent
is_a: CHEBI:46787 ! solvent

[Term]
id: CHEBI:48358
name: polar aprotic solvent
def: "A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds." []
is_a: CHEBI:48354 ! polar solvent
is_a: CHEBI:48357 ! aprotic solvent

[Term]
id: CHEBI:48359
name: protophilic solvent
def: "Solvent that is capable of acting as a hydron (proton) acceptor." []
is_a: CHEBI:39142 ! Bronsted base
is_a: CHEBI:48354 ! polar solvent

[Term]
id: CHEBI:48360
name: amphiprotic solvent
def: "Self-ionizing solvent possessing both characteristics of Brønsted acids and bases." []
is_a: CHEBI:48356 ! protic solvent
is_a: CHEBI:48359 ! protophilic solvent

[Term]
id: CHEBI:48367
name: hydrobromide
def: "Salts formally resulting from the reaction of hydrobromic acid with an organic base." []
is_a: CHEBI:48369 ! organic bromide salt

[Term]
id: CHEBI:48369
name: organic bromide salt
is_a: CHEBI:22925 ! bromide salt
is_a: CHEBI:51069 ! organic halide salt

[Term]
id: CHEBI:48376
name: carbamimidic acid
is_a: CHEBI:48379 ! isourea
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018036 CHEBI:16199 ! is tautomer of urea

[Term]
id: CHEBI:48377
name: imidic acid
def: "Compounds derived from oxoacids R<small><sub><em>k</em></sub></small>E(=O)<small><sub><em>l</em></sub></small>(OH)<small><sub><em>m</em></sub></small> (<em>l</em> ≠ 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH)." []
is_a: CHEBI:33241 ! oxoacid derivative
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:48378
name: carboximidic acid
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:48377 ! imidic acid

[Term]
id: CHEBI:48379
name: isourea
def: "A carboximidic acid that is the imidic acid tautomer of urea, H<small><sub>2</sub></small>NC(=NH)OH, and its hydrocarbyl derivatives." []
is_a: CHEBI:48378 ! carboximidic acid

[Term]
id: CHEBI:48397
name: methanediol
def: "The simplest member of the class of methanediols that is methane in which two of the hydrogens have been substituted by hydroxy groups." []
is_a: CHEBI:25222 ! methanediols
is_a: CHEBI:63733 ! aldehyde hydrate
is_a: CHEBI:64708 ! one-carbon compound

[Term]
id: CHEBI:48407
name: antiparkinson drug
def: "A drug used in the treatment of Parkinson's disease." []
is_a: CHEBI:66956 ! antidyskinesia agent

[Term]
id: CHEBI:48408
name: ethyl vanillin
def: "A member of the class of benzaldehydes that is vanillin in which the methoxy group is replaced by an ethoxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22698 ! benzaldehydes
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0018038 CHEBI:18346 ! has functional parent vanillin

[Term]
id: CHEBI:48420
name: biphenylyltetrazole
def: "A member of the class of biphenyls that consists of a biphenyl ring system substituted by a tetrazole ring at an unspecified position." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:35689 ! tetrazoles

[Term]
id: CHEBI:48422
name: angiogenesis inhibitor
def: "An agent and endogenous substances that antagonize or inhibit the development of new blood vessels." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:48425
name: topical anaesthetic
def: "A local anesthetic that is used to numb the surface of a body part." []
is_a: CHEBI:36333 ! local anaesthetic

[Term]
id: CHEBI:48430
name: 4-methyl-2-oxopentanoic acid
def: "A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease." []
synonym: "4-Methyl-2-oxopentanoate" EXACT [KEGG_COMPOUND]
is_a: CHEBI:191197 ! branched-chain keto acid
is_a: CHEBI:35910 ! 2-oxo monocarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:17865 ! is protonated form of 4-methyl-2-oxopentanoate
relationship: RO:0018038 CHEBI:17418 ! has functional parent valeric acid

[Term]
id: CHEBI:48431
name: formimidic acid
def: "A carboximidic acid that is  formic acid in which the carbonyl oxygen is replaced by an imino group." []
is_a: CHEBI:48378 ! carboximidic acid
is_a: CHEBI:64708 ! one-carbon compound
relationship: RO:0018036 CHEBI:16397 ! is tautomer of formamide
relationship: RO:0018038 CHEBI:30751 ! has functional parent formic acid

[Term]
id: CHEBI:48432
name: angiotensin II
is_a: CHEBI:48433 ! angiotensin
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent

[Term]
id: CHEBI:48433
name: angiotensin
is_a: CHEBI:25905 ! peptide hormone

[Term]
id: CHEBI:48436
name: thiophenecarboxylic acid
is_a: CHEBI:26961 ! thiophenes
is_a: CHEBI:33575 ! carboxylic acid

[Term]
id: CHEBI:48437
name: cyclopentapyrimidine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:48442
name: purine 2',3'-dideoxyribonucleoside
is_a: CHEBI:47945 ! 2',3'-dideoxyribonucleoside
is_a: CHEBI:60173 ! purine deoxyribonucleoside

[Term]
id: CHEBI:48470
name: amidobenzoic acid
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:29347 ! monocarboxylic acid amide
relationship: RO:0018034 CHEBI:61666 ! is protonated form of amidobenzoate

[Term]
id: CHEBI:48471
name: sulfamoylbenzoate
is_a: CHEBI:22718 ! benzoates
is_a: CHEBI:35358 ! sulfonamide

[Term]
id: CHEBI:48498
name: thiophenol
def: "A thiol in which the sulfanyl group is attached to a phenyl group." []
is_a: CHEBI:82711 ! aryl thiol

[Term]
id: CHEBI:48513
name: carbazoles
is_a: CHEBI:39205 ! dibenzopyrrole

[Term]
id: CHEBI:48518
name: 3-isobutyl-1-methylxanthine
def: "An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively." []
is_a: CHEBI:25810 ! oxopurine
relationship: RO:0018038 CHEBI:15318 ! has functional parent xanthine

[Term]
id: CHEBI:48526
name: hydratropic acid
def: "A 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of α-methylstyrene (AMS), a volatile hydrocarbon." []
is_a: CHEBI:16333 ! 2-arylpropionic acid
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018038 CHEBI:30745 ! has functional parent phenylacetic acid

[Term]
id: CHEBI:48527
name: (S)-hydratropic acid
is_a: CHEBI:48526 ! hydratropic acid
relationship: RO:0018039 CHEBI:43035 ! is enantiomer of (R)-hydratropic acid

[Term]
id: CHEBI:48535
name: aryloxypyrimidine
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:39447 ! pyrimidines

[Term]
id: CHEBI:48539
name: alpha-adrenergic drug
def: "Any drug that acts on an α-adrenergic receptor." []
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:48540
name: beta-adrenergic drug
def: "Any of the drugs that act on β-adrenergic receptors." []
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:48544
name: methanesulfonates
def: "Esters or salts of methanesulfonic acid." []
is_a: CHEBI:33261 ! organosulfur compound
relationship: RO:0018038 CHEBI:27376 ! has functional parent methanesulfonic acid

[Term]
id: CHEBI:48546
name: pyrimidinethione
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:50492 ! thiocarbonyl compound

[Term]
id: CHEBI:48550
name: EC 1.1.1.21 (aldehyde reductase) inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21)." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:48551
name: guanidino group
is_a: CHEBI:33456 ! organoheteryl group
relationship: RO:0018037 CHEBI:42820 ! is substitutent group from guanidine
relationship: RO:0018037 CHEBI:616459 ! is substitutent group from carbamimidoylazanium

[Term]
id: CHEBI:48552
name: medetomidine
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:60911 ! racemate

[Term]
id: CHEBI:48555
name: levomedetomidine
is_a: CHEBI:48552 ! medetomidine
relationship: RO:0018039 CHEBI:4466 ! is enantiomer of dexmedetomidine

[Term]
id: CHEBI:48560
name: dopaminergic agent
def: "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:48561
name: dopaminergic antagonist
def: "A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists." []
is_a: CHEBI:48560 ! dopaminergic agent
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:48563
name: methylsulfanyl group
is_a: CHEBI:33456 ! organoheteryl group
relationship: RO:0018037 CHEBI:16007 ! is substitutent group from methanethiol

[Term]
id: CHEBI:48565
name: methyl 17-hydroxy-20xi-yohimban-16-carboxylate
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:27358 ! yohimban alkaloid
is_a: CHEBI:38164 ! organic heteropentacyclic compound

[Term]
id: CHEBI:48578
name: radical scavenger
def: "A role played by a substance that can react readily with, and thereby eliminate, radicals." []
is_a: CHEBI:22586 ! antioxidant

[Term]
id: CHEBI:48585
name: heteroarylpiperidine
is_a: CHEBI:26151 ! piperidines

[Term]
id: CHEBI:48589
name: piperidones
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:48590
name: hydroxypiperidine
is_a: CHEBI:26151 ! piperidines

[Term]
id: CHEBI:48591
name: N-acylpiperidine
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:32988 ! amide

[Term]
id: CHEBI:48597
name: arsenate(2-)
def: "An arsenate ion resulting from the removal of two protons from arsenic acid." []
is_a: CHEBI:22629 ! arsenate ion
relationship: RO:0018033 CHEBI:48600 ! is deprotonated form of arsenate(1-)
relationship: RO:0018034 CHEBI:29125 ! is protonated form of arsenate(3-)

[Term]
id: CHEBI:48600
name: arsenate(1-)
def: "An arsenate ion resulting from the removal of one proton from arsenic acid." []
is_a: CHEBI:22629 ! arsenate ion
relationship: RO:0018034 CHEBI:48597 ! is protonated form of arsenate(2-)

[Term]
id: CHEBI:48607
name: lithium chloride
def: "A metal chloride salt with a Li(+) counterion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35478 ! lithium salt
is_a: CHEBI:36093 ! inorganic chloride
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:35477 ! has role antimanic drug

[Term]
id: CHEBI:48626
name: pyranoindolizinoquinoline
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:38164 ! organic heteropentacyclic compound

[Term]
id: CHEBI:48654
name: pyrazolylpiperidine
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:48585 ! heteroarylpiperidine

[Term]
id: CHEBI:48676
name: fibrin modulating drug
def: "A drug that affects the function of fibrin in blood coagulation." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:48684
name: benzothiazepine
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:48705
name: agonist
def: "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." []
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:48706
name: antagonist
def: "Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances." []
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:48721
name: mononitroanisoles
def: "Any member of the class of nitroanisoles in which a single nitro group is attached to the anisole ring." []
is_a: CHEBI:48726 ! nitroanisoles

[Term]
id: CHEBI:48722
name: 2-nitroanisole
def: "A member of the class of 2-nitroanisoles that is anisole in which one of the hydrogens <em>ortho</em> to the methoxy group is replaced by a nitro group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48727 ! 2-nitroanisoles
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:48726
name: nitroanisoles
def: "A monomethoxybenzene carrying one or more nitro substituents." []
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:35716 ! C-nitro compound
relationship: RO:0018038 CHEBI:16579 ! has functional parent anisole

[Term]
id: CHEBI:48727
name: 2-nitroanisoles
def: "Any member of the class of mononitroanisoles in which the nitro group is situated <em>ortho</em> to the methoxy group." []
is_a: CHEBI:48721 ! mononitroanisoles

[Term]
id: CHEBI:48730
name: aluminosilicate mineral
def: "Silicate minerals that contain aluminium, silicon, and oxygen, together with other ions. They are a major component of clay minerals." []
is_a: CHEBI:46663 ! silicate mineral

[Term]
id: CHEBI:4875
name: etanercept
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:48765
name: dimethylarsinic acid
def: "The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33406 ! organoarsenic compound
relationship: RO:0000087 CHEBI:76206 ! has role xenobiotic metabolite
relationship: RO:0018034 CHEBI:16223 ! is protonated form of dimethylarsinate
relationship: RO:0018038 CHEBI:29840 ! has functional parent arsinic acid

[Term]
id: CHEBI:4877
name: ethambutol
def: "An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (<i>S</i>,<i>S</i>-configuration). It is a bacteriostatic antimycobacterial drug, effective against <em>Mycobacterium tuberculosis</em> and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of <em>M. tuberculosis</em> are readily produced if ethambutol is used alone." []
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:31577 ! ethylenediamine derivative
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:48775
name: cadmium(2+)
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation
is_a: CHEBI:63063 ! cadmium cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:48819
name: cyano group
is_a: CHEBI:36823 ! pseudohalo group
relationship: RO:0018037 CHEBI:18407 ! is substitutent group from hydrogen cyanide

[Term]
id: CHEBI:48828
name: cobalt(2+)
synonym: "cobalt(2+) ion" EXACT [ChEBI]
synonym: "cobalt(II) cation" EXACT [ChEBI]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23336 ! cobalt cation
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:48844
name: roxithromycin
def: "Semisynthetic derivative of erythromycin A." []
is_a: CHEBI:48924 ! erythromycin derivative
is_a: CHEBI:72588 ! semisynthetic derivative
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0018038 CHEBI:42355 ! has functional parent erythromycin A

[Term]
id: CHEBI:48847
name: heterocyclic fatty acid
def: "Any fatty acid containing a ring composed of atoms including at least one heteroatom." []
is_a: CHEBI:5686 ! heterocyclic compound
is_a: CHEBI:59238 ! cyclic fatty acid

[Term]
id: CHEBI:48848
name: erythronolide A
is_a: CHEBI:23955 ! erythronolide

[Term]
id: CHEBI:48850
name: alkyloxynaphthalene
def: "Naphthalenes in which one or more alkyloxy groups are bonded to a naphthalene ring system." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:48851
name: methoxynaphthalene
def: "Any alkyloxynaphthalene bearing one or more methoxy substituents." []
is_a: CHEBI:48850 ! alkyloxynaphthalene

[Term]
id: CHEBI:48853
name: dimethylnaphthalene
def: "Any member of the class of  naphthalenes carrying two methyl groups at unspecified positions." []
is_a: CHEBI:25477 ! naphthalenes
relationship: RO:0018040 CHEBI:16482 ! has parent hydride naphthalene

[Term]
id: CHEBI:48854
name: sulfurous acid
synonym: "Sulfite" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33402 ! sulfur oxoacid
relationship: RO:0018034 CHEBI:17137 ! is protonated form of hydrogensulfite
relationship: RO:0018036 CHEBI:29214 ! is tautomer of sulfonic acid

[Term]
id: CHEBI:48857
name: sulfite salt
is_a: CHEBI:24839 ! inorganic salt
is_a: CHEBI:26823 ! sulfites

[Term]
id: CHEBI:48864
name: benzothiadiazole
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:48873
name: cholinergic antagonist
def: "Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists." []
is_a: CHEBI:38323 ! cholinergic drug

[Term]
id: CHEBI:48876
name: muscarinic antagonist
def: "A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists." []
is_a: CHEBI:48873 ! cholinergic antagonist

[Term]
id: CHEBI:48878
name: nicotinic antagonist
def: "An antagonist at the nicotinic cholinergic receptor." []
is_a: CHEBI:48873 ! cholinergic antagonist

[Term]
id: CHEBI:48888
name: pyridoindole
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:48891
name: thiazolidinone
is_a: CHEBI:35622 ! thiazolidines

[Term]
id: CHEBI:48898
name: oxadiazane
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:48901
name: thiazoles
def: "An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom." []
is_a: CHEBI:38106 ! organosulfur heterocyclic compound
is_a: CHEBI:68452 ! azole

[Term]
id: CHEBI:48902
name: 1,2-thiazoles
is_a: CHEBI:48901 ! thiazoles

[Term]
id: CHEBI:48909
name: imidazothiazole
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:48912
name: benzotriazoles
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:48923
name: erythromycin
def: "Any of several wide-spectrum macrolide antibiotics obtained from actinomycete <em>Saccharopolyspora erythraea</em> (formerly known as <em>Streptomyces erythraeus</em>)." []
is_a: CHEBI:23953 ! erythromycins
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:64290 ! is protonated form of erythromycin cation

[Term]
id: CHEBI:48924
name: erythromycin derivative
is_a: CHEBI:23953 ! erythromycins

[Term]
id: CHEBI:48927
name: N-acyl-L-alpha-amino acid
def: "Any <small>L</small>-α-amino acid carrying an <em>N</em>-acyl substituent." []
is_a: CHEBI:21644 ! N-acyl-L-amino acid
relationship: RO:0018034 CHEBI:59874 ! is protonated form of N-acyl-L-alpha-amino acid anion
relationship: RO:0018038 CHEBI:15705 ! has functional parent L-alpha-amino acid

[Term]
id: CHEBI:48929
name: 3-carboxy-2,3-dihydroxypropanoate
def: "A tartaric acid anion that is the conjugate base of 2,3-dihydroxybutanedioic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132950 ! tartrate
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:15674 ! is deprotonated form of 2,3-dihydroxybutanedioic acid
relationship: RO:0018034 CHEBI:30929 ! is protonated form of 2,3-dihydroxybutanedioate

[Term]
id: CHEBI:48935
name: (E)-roxithromycin
def: "A major geometrical isomer of roxithromycin." []
is_a: CHEBI:48844 ! roxithromycin
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:48942
name: isovalerate
def: "A branched-chain saturated fatty acid anion that is the conjugate base of isovaleric acid; reported to improve ruminal fermentation and feed digestion in cattle." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58951 ! short-chain fatty acid anion
is_a: CHEBI:58956 ! branched-chain saturated fatty acid anion
is_a: CHEBI:83972 ! 3-methyl fatty acid anion
relationship: RO:0000087 CHEBI:75768 ! has role mammalian metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:28484 ! is deprotonated form of isovaleric acid

[Term]
id: CHEBI:48943
name: isobutyraldehyde
def: "A member of the class of propanals that is propanal substituted by a methyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26282 ! propanals
is_a: CHEBI:49188 ! 2-methyl-branched fatty aldehyde
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite

[Term]
id: CHEBI:48946
name: 2-methylbutyrate
is_a: CHEBI:58951 ! short-chain fatty acid anion
is_a: CHEBI:58956 ! branched-chain saturated fatty acid anion
relationship: RO:0018033 CHEBI:37070 ! is deprotonated form of 2-methylbutyric acid

[Term]
id: CHEBI:48958
name: 1,1'-azobis(N,N-dimethylformamide)
is_a: CHEBI:48959 ! monoazo compound

[Term]
id: CHEBI:48959
name: monoazo compound
def: "Compounds containing single ‒N=N‒ group." []
is_a: CHEBI:37533 ! azo compound

[Term]
id: CHEBI:48960
name: bis(azo) compound
def: "Any  azo compound containing two ‒N=N‒ groups." []
is_a: CHEBI:37533 ! azo compound

[Term]
id: CHEBI:48975
name: substituted aniline
is_a: CHEBI:22562 ! anilines

[Term]
id: CHEBI:48976
name: 4-nitroanisoles
def: "Any member of the class of mononitroanisoles in which the nitro group is situated <em>para</em> to the methoxy group." []
is_a: CHEBI:48721 ! mononitroanisoles

[Term]
id: CHEBI:48977
name: 2-methoxy-5-nitroaniline
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:48976 ! 4-nitroanisoles

[Term]
id: CHEBI:48999
name: 4-hydroxyphenylacetate
def: "A monocarboxylic acid anion that is obtained by removal of a proton from the carboxylic acid group of 4-hydroxyphenylacetic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76946 ! has role fungal metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:18101 ! is deprotonated form of 4-hydroxyphenylacetic acid
relationship: RO:0018038 CHEBI:30089 ! has functional parent acetate

[Term]
id: CHEBI:49000
name: 2-phenylethanol
def: "A primary alcohol that is ethanol substituted by a phenyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:22712 ! benzenes
relationship: RO:0000087 CHEBI:35219 ! has role plant growth retardant
relationship: RO:0000087 CHEBI:48318 ! has role fragrance
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76956 ! has role Aspergillus metabolite

[Term]
id: CHEBI:49005
name: deferasirox
def: "A member of the class of triazoles, deferasirox is 1,2,4-triazole substituted by a 4-carboxyphenyl group at position 1 and by 2-hydroxyphenyl groups at positions 3 and 5. An orally active iron chelator, it is used to manage chronic iron overload in patients receiving long-term blood transfusions." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35727 ! triazoles
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38157 ! has role iron chelator
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:855 ! has functional parent 2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol

[Term]
id: CHEBI:49007
name: D-citrulline
is_a: CHEBI:18211 ! citrulline
relationship: RO:0018039 CHEBI:16349 ! is enantiomer of L-citrulline

[Term]
id: CHEBI:490095
name: esculetin
def: "A  hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37912 ! hydroxycoumarin
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:73335 ! has role ultraviolet filter
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:49020
name: hormone antagonist
def: "A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." []
is_a: CHEBI:48706 ! antagonist
is_a: CHEBI:51061 ! hormone receptor modulator

[Term]
id: CHEBI:49023
name: prostaglandin antagonist
def: "A compound that inhibits the action of prostaglandins." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:49028
name: acetimidic acid
def: "A carboximidic acid that is  acetic acid in which the carbonyl oxygen is replaced by an imino group." []
is_a: CHEBI:48378 ! carboximidic acid
relationship: RO:0018036 CHEBI:27856 ! is tautomer of acetamide
relationship: RO:0018038 CHEBI:15366 ! has functional parent acetic acid

[Term]
id: CHEBI:49029
name: N-hydroxyacetimidic acid
def: "A carbohydroximic acid consisting of acetimidic acid having a hydroxy group attached to the imide nitrogen." []
is_a: CHEBI:61398 ! carbohydroximic acid
relationship: RO:0018036 CHEBI:27777 ! is tautomer of acetohydroxamic acid
relationship: RO:0018038 CHEBI:49028 ! has functional parent acetimidic acid

[Term]
id: CHEBI:4903
name: 17alpha-ethynylestradiol
def: "A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a  xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36834 ! 3-hydroxy steroid
is_a: CHEBI:36838 ! 17-hydroxy steroid
is_a: CHEBI:73477 ! terminal acetylenic compound
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:76988 ! has role xenoestrogen
relationship: RO:0018038 CHEBI:16469 ! has functional parent 17beta-estradiol

[Term]
id: CHEBI:49043
name: beta-lactone
is_a: CHEBI:25000 ! lactone

[Term]
id: CHEBI:49073
name: beta-propiolactone
is_a: CHEBI:49074 ! propan-3-olide
relationship: RO:0018038 CHEBI:33404 ! has functional parent 3-hydroxypropionic acid
relationship: RO:0018040 CHEBI:30965 ! has parent hydride oxetane

[Term]
id: CHEBI:49074
name: propan-3-olide
is_a: CHEBI:49043 ! beta-lactone

[Term]
id: CHEBI:490877
name: didanosine
def: "A purine 2',3'-dideoxyribonucleoside that is inosine in which the hydroxy groups at both the 2' and the 3' positions on the sugar moiety have been replaced by hydrogen. An antiviral drug, it is used as a medication to treat HIV/AIDS." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25810 ! oxopurine
is_a: CHEBI:48442 ! purine 2',3'-dideoxyribonucleoside
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor
relationship: RO:0000087 CHEBI:63090 ! has role EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor

[Term]
id: CHEBI:49095
name: beta-amino-acid anion
is_a: CHEBI:37022 ! amino-acid anion

[Term]
id: CHEBI:4910
name: etomidate
def: "The ethyl ester of 1-[(1<i>R</i>)-1-phenylethyl]-1<em>H</em>-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:24780 ! imidazoles
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35717 ! has role sedative
relationship: RO:0000087 CHEBI:38877 ! has role intravenous anaesthetic
relationship: RO:0018038 CHEBI:60458 ! has functional parent 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid

[Term]
id: CHEBI:49103
name: drug metabolite
is_a: CHEBI:76967 ! human xenobiotic metabolite

[Term]
id: CHEBI:49105
name: thiamine hydrochloride
def: "A hydrochloride obtained by combining thiamine chloride with one molar equivalent of hydrochloric acid." []
is_a: CHEBI:26948 ! vitamin B1
is_a: CHEBI:36807 ! hydrochloride
relationship: BFO:0000051 CHEBI:49107 ! has part thiamine(2+)
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:71692 ! has role insect repellent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:49107
name: thiamine(2+)
def: "A primary ammonium ion that is the conjugate acid of thiamine(1+) resulting from the protonation of the primary amino group." []
is_a: CHEBI:26948 ! vitamin B1
is_a: CHEBI:65296 ! primary ammonium ion
relationship: RO:0018034 CHEBI:18385 ! is protonated form of thiamine(1+)

[Term]
id: CHEBI:4911
name: etoposide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22798 ! beta-D-glucoside
is_a: CHEBI:50307 ! furonaphthodioxole
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0018038 CHEBI:50305 ! has functional parent podophyllotoxin
relationship: RO:0018038 CHEBI:74422 ! has functional parent 4'-demethylepipodophyllotoxin

[Term]
id: CHEBI:49110
name: peripheral nervous system drug
def: "A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:49159
name: leukotriene antagonist
def: "A drug designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:49165
name: montelukast(1-)
is_a: CHEBI:22327 ! aliphatic sulfide
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:50730 ! is deprotonated form of montelukast

[Term]
id: CHEBI:49167
name: anti-asthmatic drug
def: "A drug used to treat asthma." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:65023 ! anti-asthmatic agent

[Term]
id: CHEBI:49168
name: dopa
def: "A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring." []
is_a: CHEBI:24734 ! hydroxyphenylalanine
is_a: CHEBI:62761 ! tyrosine derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:49169
name: D-dopa
def: "The <small>D</small>-enantiomer of dopa." []
is_a: CHEBI:49168 ! dopa
is_a: CHEBI:84124 ! D-tyrosine derivative
relationship: RO:0018036 CHEBI:149689 ! is tautomer of D-dopa zwitterion
relationship: RO:0018039 CHEBI:15765 ! is enantiomer of L-dopa

[Term]
id: CHEBI:4917
name: eugenol
def: "A phenylpropanoid formally derived from guaiacol with an allyl chain substituted <em>para</em> to the hydroxy group. It is a major component of clove essential oil, and exhibits antibacterial, analgesic and antioxidant properties. It has been widely used in dentistry to treat toothache and pulpitis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:195237 ! alkenylbenzene
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:26004 ! phenylpropanoid
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:139492 ! has role sensitiser
relationship: RO:0000087 CHEBI:27311 ! has role volatile oil component
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0000087 CHEBI:38623 ! has role EC 1.4.3.4 (monoamine oxidase) inhibitor
relationship: RO:0000087 CHEBI:38634 ! has role voltage-gated sodium channel blocker
relationship: RO:0000087 CHEBI:38867 ! has role anaesthetic
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:73240 ! has role NF-kappaB inhibitor
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018038 CHEBI:28591 ! has functional parent guaiacol

[Term]
id: CHEBI:4918
name: O-methyleugenol
is_a: CHEBI:26004 ! phenylpropanoid
relationship: RO:0018038 CHEBI:4917 ! has functional parent eugenol

[Term]
id: CHEBI:49188
name: 2-methyl-branched fatty aldehyde
is_a: CHEBI:35746 ! fatty aldehyde

[Term]
id: CHEBI:49200
name: EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
def: "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H<small><sup>+</small></sup>/K<small><sup>+</small></sup>-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors." []
is_a: CHEBI:76895 ! EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor

[Term]
id: CHEBI:49201
name: anti-ulcer drug
def: "One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:49202
name: elemental platinum
is_a: CHEBI:33749 ! platinum molecular entity

[Term]
id: CHEBI:49205
name: CETP inhibitor
def: "Any inhibitor of cholesterylester transfer protein (CETP), which transfers cholesterol from high density lipoproteins (HDL, the 'good' cholesterol-containing particles) to low or very low density lipoproteins (LDL or VLDL, the 'bad' cholesterol-containing particles). Inhibition of this process results in higher HDL levels and lower LDL levels. CETP inhibitors are under investigation as potential drugs to reduce the risk of arteriosclerotic vascular disease (atherosclerosis)." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:49267
name: bisanthene
is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene

[Term]
id: CHEBI:49302
name: 2-hydroxy monocarboxylic acid
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid

[Term]
id: CHEBI:49318
name: piperidine antibiotic
is_a: CHEBI:25558 ! organonitrogen heterocyclic antibiotic
is_a: CHEBI:26151 ! piperidines

[Term]
id: CHEBI:49319
name: carbocyclic antibiotic
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33598 ! carbocyclic compound
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:49322
name: anthracycline antibiotic
def: "An organic compound that has a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine and which exhibits antibiotic activity." []
is_a: CHEBI:48120 ! anthracycline
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:49323
name: contraceptive drug
def: "A chemical substance that prevents or reduces the probability of conception." []
is_a: CHEBI:50689 ! reproductive control drug

[Term]
id: CHEBI:49324
name: female contraceptive drug
def: "A chemical substance or agent with contraceptive activity in females." []
is_a: CHEBI:49323 ! contraceptive drug

[Term]
id: CHEBI:49325
name: oral contraceptive
def: "A compound, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy." []
is_a: CHEBI:49324 ! female contraceptive drug

[Term]
id: CHEBI:49326
name: synthetic oral contraceptive
def: "An oral contraceptive which owes its effectiveness to synthetic preparation." []
is_a: CHEBI:49325 ! oral contraceptive

[Term]
id: CHEBI:49339
name: methyl L-phenylalaninate
def: "An α-amino acid ester that is the methyl ester of <small>L</small>-phenylalanine." []
is_a: CHEBI:46874 ! alpha-amino acid ester
is_a: CHEBI:84144 ! L-phenylalanine derivative

[Term]
id: CHEBI:49375
name: dasatinib (anhydrous)
def: "An aminopyrimidine that is 2-methylpyrimidine which is substituted at position 4 by the primary amino group of 2-amino-1,3-thiazole-5-carboxylic acid and at position 6 by a 4-(2-hydroxyethyl)piperazin-1-yl group, and in which the carboxylic acid group has been formally condensed with 2-chloro-6-methylaniline to afford the corresponding amide. A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN) as well as to anhydrous dasatinib (INN)." []
synonym: "N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE" EXACT [PDBeChem]
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:38418 ! 1,3-thiazoles
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:46851 ! N-(2-hydroxyethyl)piperazine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018033 CHEBI:190514 ! is deprotonated form of dasatinib(1+)

[Term]
id: CHEBI:49382
name: bromic acid
synonym: "bromic acid" EXACT [PDBeChem]
is_a: CHEBI:33427 ! bromine oxoacid
relationship: RO:0018034 CHEBI:29223 ! is protonated form of bromate

[Term]
id: CHEBI:4940
name: Euphol
is_a: CHEBI:36615 ! triterpenoid

[Term]
id: CHEBI:49468
name: silver(1+)
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25414 ! monoatomic monocation
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:60242 ! monovalent inorganic cation
is_a: CHEBI:60253 ! silver cation
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent

[Term]
id: CHEBI:49470
name: aluminium(3+)
def: "An aluminium cation that has a charge of +3." []
is_a: CHEBI:27153 ! monoatomic trication
is_a: CHEBI:33627 ! monoatomic aluminium
is_a: CHEBI:63062 ! aluminium cation

[Term]
id: CHEBI:49475
name: argon atom
synonym: "Ar" EXACT [IUPAC]
synonym: "argon" EXACT [ChEBI]
is_a: CHEBI:33309 ! noble gas atom
is_a: CHEBI:33560 ! p-block element atom

[Term]
id: CHEBI:49496
name: gold(3+)
is_a: CHEBI:231853 ! gold cation
is_a: CHEBI:27153 ! monoatomic trication

[Term]
id: CHEBI:4953
name: exemestane
def: "A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19168 ! 17-oxo steroid
is_a: CHEBI:36834 ! 3-hydroxy steroid
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50113 ! has role androgen
relationship: RO:0000087 CHEBI:50790 ! has role EC 1.14.14.14 (aromatase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018040 CHEBI:35509 ! has parent hydride androstane

[Term]
id: CHEBI:49544
name: chromium(3+)
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27153 ! monoatomic trication
is_a: CHEBI:33516 ! chromium cation
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:49547
name: caesium(1+)
synonym: "caesium" EXACT [IUPAC]
is_a: CHEBI:231854 ! caesium cation
is_a: CHEBI:25414 ! monoatomic monocation
is_a: CHEBI:60242 ! monovalent inorganic cation

[Term]
id: CHEBI:49553
name: copper(II) chloride
def: "An inorganic chloride of copper in which the metal is in the +2 oxidation state." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23377 ! copper molecular entity
is_a: CHEBI:36093 ! inorganic chloride
relationship: BFO:0000051 CHEBI:29036 ! has part copper(2+)
relationship: RO:0000087 CHEBI:86385 ! has role EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor

[Term]
id: CHEBI:49575
name: diazepam
def: "A 1,4-benzodiazepinone that is 1,3-dihydro-2<em>H</em>-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5." []
is_a: CHEBI:35500 ! 1,4-benzodiazepinone
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35717 ! has role sedative
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:49603
name: lapatinib
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24129 ! furans
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38530 ! quinazolines
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0018038 CHEBI:5115 ! has functional parent monofluorobenzene

[Term]
id: CHEBI:49631
name: gallium atom
def: "A metallic element predicted as eka-aluminium by Mendeleev in 1870 and discovered by Paul-Emile Lecoq de Boisbaudran in 1875. Named in honour of France (Latin <em>Gallia</em>) and perhaps also from the Latin <em>gallus</em> cock, a translation of Lecoq." []
is_a: CHEBI:233500 ! post-transition metal atom
is_a: CHEBI:33317 ! boron group element atom

[Term]
id: CHEBI:49637
name: hydrogen atom
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24835 ! inorganic molecular entity
is_a: CHEBI:25585 ! nonmetal atom
is_a: CHEBI:33559 ! s-block element atom
relationship: RO:0000087 CHEBI:33937 ! has role macronutrient

[Term]
id: CHEBI:49662
name: indometacin
def: "A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by <em>p</em>-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis." []
is_a: CHEBI:24803 ! indole-3-acetic acids
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:75884 ! N-acylindole
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35544 ! has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:49666
name: iridium atom
is_a: CHEBI:33358 ! cobalt group element atom
is_a: CHEBI:33365 ! platinum group metal atom

[Term]
id: CHEBI:49668
name: gefitinib
def: "A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer." []
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38530 ! quinazolines
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:83575 ! monofluorobenzenes
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:74440 ! has role epidermal growth factor receptor antagonist

[Term]
id: CHEBI:49703
name: latrunculin B
def: "A macrolide consisting of a 14-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge <em>Latrunculia magnifica</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25106 ! macrolide
is_a: CHEBI:46733 ! oxabicycloalkane
is_a: CHEBI:48891 ! thiazolidinone
is_a: CHEBI:59780 ! cyclic hemiketal
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:70728 ! has role actin polymerisation inhibitor

[Term]
id: CHEBI:49704
name: iridium(3+)
is_a: CHEBI:27153 ! monoatomic trication
is_a: CHEBI:37228 ! iridium molecular entity

[Term]
id: CHEBI:49706
name: perchlorate
def: "A monovalent inorganic anion obtained by deprotonation of perchloric acid." []
is_a: CHEBI:33437 ! chlorine oxoanion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:29221 ! is deprotonated form of perchloric acid

[Term]
id: CHEBI:49709
name: chlorate
def: "A monovalent inorganic anion obtained by deprotonation of chloric acid." []
is_a: CHEBI:33437 ! chlorine oxoanion
is_a: CHEBI:79389 ! monovalent inorganic anion
relationship: RO:0018033 CHEBI:17322 ! is deprotonated form of chloric acid

[Term]
id: CHEBI:49713
name: lithium(1+)
is_a: CHEBI:25414 ! monoatomic monocation
is_a: CHEBI:33504 ! alkali metal cation
is_a: CHEBI:60242 ! monovalent inorganic cation

[Term]
id: CHEBI:49747
name: methylmercury(1+)
is_a: CHEBI:25322 ! methylmercury compound

[Term]
id: CHEBI:497734
name: L-thialysine
def: "A cysteine derivative that is the <i>S</i>-(2-aminoethyl) analogue of <small>L</small>-cysteine; reported to have cytotoxic effects." []
is_a: CHEBI:27532 ! L-cysteine thioether
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:75190 ! has role EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor
relationship: RO:0018033 CHEBI:156132 ! is deprotonated form of L-thialysinium

[Term]
id: CHEBI:49786
name: nickel(2+)
def: "A nickel cation in which the nickel carries a double positive charge." []
is_a: CHEBI:25516 ! nickel cation
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation
is_a: CHEBI:88186 ! metal cation allergen

[Term]
id: CHEBI:49807
name: lead(2+)
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:30412 ! monoatomic dication
is_a: CHEBI:60240 ! divalent metal cation
is_a: CHEBI:60252 ! lead cation
relationship: RO:0000087 CHEBI:23357 ! has role cofactor

[Term]
id: CHEBI:4986
name: fatty acid methyl ester
def: "A fatty acid ester that is the carboxylic ester obtained by the formal condensation of a fatty acid with methanol." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:35748 ! fatty acid ester

[Term]
id: CHEBI:49900
name: arsenous acid
def: "An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom." []
is_a: CHEBI:33407 ! arsenic oxoacid
relationship: RO:0018034 CHEBI:29242 ! is protonated form of arsenite(1-)

[Term]
id: CHEBI:49960
name: vandetanib
def: "A quinazoline that is 7-[(1-methylpiperidin-4-yl)methoxy]quinazoline bearing additional methoxy and 4-bromo-2-fluorophenylamino substituents at positions 6 and 4 respectively. Used for the treatment of symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease." []
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37141 ! organobromine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38530 ! quinazolines
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor

[Term]
id: CHEBI:49976
name: zinc dichloride
def: "A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn<small><sup>2+</small></sup> ions are trigonal planar coordinated to four chloride ions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:27364 ! zinc molecular entity
is_a: CHEBI:36093 ! inorganic chloride
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:39143 ! has role Lewis acid
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:74783 ! has role astringent
relationship: RO:0000087 CHEBI:86385 ! has role EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor

[Term]
id: CHEBI:4998
name: fenarimol
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-fenarimol. A sterol demethylation inhibitor, it is used as a fungicide for the treatment of blackspot, mildew and rust in tomatoes, peppers and melons, but is not approved for use within the European Union." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87207 ! pyrimidine fungicide
relationship: BFO:0000051 CHEBI:83688 ! has part (R)-fenarimol
relationship: BFO:0000051 CHEBI:83689 ! has part (S)-fenarimol
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:5001
name: fenofibrate
def: "A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23135 ! chlorobenzophenone
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:35725 ! isopropyl ester
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:41308 ! has functional parent benzophenone

[Term]
id: CHEBI:50018
name: glycosyloxyflavone
def: "A member of the class of flavones having one or more glycosyl residues attached at unspecified positions." []
is_a: CHEBI:24043 ! flavones
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:50025
name: beta-pinene
def: "An isomer of pinene with an exocyclic double bond. It is a component of essential oils from many plants." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17187 ! pinene
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:50047
name: organic amino compound
def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:39142 ! has role Bronsted base
relationship: RO:0018040 CHEBI:16134 ! has parent hydride ammonia

[Term]
id: CHEBI:50075
name: dihydropyridine
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:5008
name: Fenoxaprop ethyl
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:50081
name: oxygen halide
is_a: CHEBI:25806 ! oxygen molecular entity

[Term]
id: CHEBI:5009
name: fenoxycarb
def: "A carbamate ester that is the <em>O</em>-ethyl carbamate of 2-(4-phenoxyphenoxy)ethylamine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:24942 ! has role juvenile hormone mimic
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:39264 ! has functional parent 4-phenoxyphenol

[Term]
id: CHEBI:50092
name: 1H-pyrazolo[4,3-d]pyrimidine
is_a: CHEBI:35570 ! mancude organic heterobicyclic parent

[Term]
id: CHEBI:50093
name: selenium coordination entity
is_a: CHEBI:26628 ! selenium molecular entity

[Term]
id: CHEBI:50094
name: sulfur coordination entity
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:50096
name: sulfinyl halide
is_a: CHEBI:37578 ! halide
is_a: CHEBI:37784 ! sulfinic acid derivative
relationship: BFO:0000051 CHEBI:29822 ! has part sulfinyl group

[Term]
id: CHEBI:50099
name: (4-chloro-2-methylphenoxy)acetic acid
def: "A chlorophenoxyacetic acid that is (4-chlorophenoxy)acetic acid substituted by a methyl group at position 2." []
is_a: CHEBI:23152 ! chlorophenoxyacetic acid
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:231609 ! is protonated form of (4-chloro-2-methylphenoxy)acetate

[Term]
id: CHEBI:50102
name: N-methyl-N-nitrosourea
def: "A member of the class of <em>N</em>-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:76551 ! N-nitrosoureas
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent

[Term]
id: CHEBI:50103
name: excitatory amino acid agonist
def: "An agent that binds to and activates excitatory amino acid receptors." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:50112
name: sex hormone
def: "Any hormone that is responsible for controlling sexual characteristics and reproductive function." []
is_a: CHEBI:24621 ! hormone

[Term]
id: CHEBI:50113
name: androgen
def: "A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors." []
is_a: CHEBI:50112 ! sex hormone

[Term]
id: CHEBI:50114
name: estrogen
def: "A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens." []
is_a: CHEBI:50112 ! sex hormone

[Term]
id: CHEBI:50122
name: rosiglitazone
is_a: CHEBI:38207 ! aminopyridine
is_a: CHEBI:50990 ! thiazolidinediones
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:83157 ! has role EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor
relationship: RO:0018034 CHEBI:188074 ! is protonated form of rosiglitazone(1-)

[Term]
id: CHEBI:50127
name: trifluoromethyl group
is_a: CHEBI:50491 ! haloalkyl group
relationship: RO:0018037 CHEBI:38825 ! is substitutent group from tetrafluoromethane
relationship: RO:0018037 CHEBI:41550 ! is substitutent group from fluoroform

[Term]
id: CHEBI:50137
name: mu-opioid receptor antagonist
def: "Any compound that exhibits antagonist activity at the μ-opioid receptor" []
is_a: CHEBI:60599 ! mu-opioid agent
is_a: CHEBI:60605 ! opioid receptor antagonist

[Term]
id: CHEBI:50139
name: heptan-3-one
def: "A dialkyl ketone with butyl and ethyl as the two alkyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18044 ! dialkyl ketone
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:59163 ! has role biomarker

[Term]
id: CHEBI:5014
name: fenvalerate
def: "A carboxylic ester obtained by formal condensation between 2-(4-chlorophenyl)-3-methylbutyric acid and cyano(3-phenoxyphenyl)methanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0000087 CHEBI:39259 ! has role pyrethroid ester acaricide
relationship: RO:0018038 CHEBI:39345 ! has functional parent 2-(4-chlorophenyl)-3-methylbutyric acid

[Term]
id: CHEBI:50141
name: bronchoconstrictor agent
def: "A drug which causes a narrowing of the lumen of a bronchus or bronchiole." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50144
name: sodium pyruvate
is_a: CHEBI:25754 ! oxo carboxylic acid
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:15361 ! has part pyruvate
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent

[Term]
id: CHEBI:50145
name: fenpropimorph
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-fenpropimorph. It is a systemic fungicide, used to control a variety of fungal diseases in cereal crops." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87134 ! morpholine fungicide
relationship: BFO:0000051 CHEBI:50146 ! has part (S)-fenpropimorph
relationship: BFO:0000051 CHEBI:50147 ! has part (R)-fenpropimorph
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:83317 ! has role sterol biosynthesis inhibitor
relationship: RO:0000087 CHEBI:83319 ! has role EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:50146
name: (S)-fenpropimorph
def: "A 4-[3-(4-<em>tert</em>-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine in which the methyl substituents on the morpholine ring are in a <i>cis</i> relationship to each other and in which the remaining stereocentre has <i>S</i> configuration." []
is_a: CHEBI:50148 ! 4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine
relationship: RO:0018039 CHEBI:50147 ! is enantiomer of (R)-fenpropimorph

[Term]
id: CHEBI:50147
name: (R)-fenpropimorph
def: "A 4-[3-(4-<em>tert</em>-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine in which the methyl substituents on the morpholine ring are in a <i>cis</i> relationship to each other and in which the remaining stereocentre has <i>R</i> configuration." []
is_a: CHEBI:50148 ! 4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine
relationship: RO:0018039 CHEBI:50146 ! is enantiomer of (S)-fenpropimorph

[Term]
id: CHEBI:50148
name: 4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine
def: "A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a 3-(<em>p</em>-<em>tert</em>-butylphenyl)-2-methylpropyl group." []
is_a: CHEBI:38785 ! morpholines

[Term]
id: CHEBI:5015
name: ferbam
def: "A dithiocarbamate salt that is the iron(III) salt of dimethyldithiocarbamic acid. Formerly used as a fungicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33892 ! iron coordination entity
is_a: CHEBI:83060 ! dithiocarbamate salt
relationship: BFO:0000051 CHEBI:29034 ! has part iron(3+)
relationship: BFO:0000051 CHEBI:84293 ! has part dimethyldithiocarbamate
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:83061 ! has functional parent dimethyldithiocarbamic acid

[Term]
id: CHEBI:50160
name: steroid acid anion
def: "Any anion formed by loss of a proton from a steroid acid." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:47891 ! is deprotonated form of steroid acid

[Term]
id: CHEBI:50176
name: keratolytic drug
def: "A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases." []
is_a: CHEBI:50177 ! dermatologic drug

[Term]
id: CHEBI:50177
name: dermatologic drug
def: "A drug used to treat or prevent skin disorders or for the routine care of skin." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50183
name: P450 inhibitor
def: "An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances." []
is_a: CHEBI:76898 ! EC 1.14.14.1 (unspecific monooxygenase) inhibitor

[Term]
id: CHEBI:50188
name: provitamin
def: "A substance that can be converted into a vitamin by animal tissues." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:50196
name: dihydroxybenzaldehyde
def: "Any member of the class of benzaldehydes in which the phenyl ring is substituted by two hydroxy groups." []
is_a: CHEBI:22698 ! benzaldehydes
is_a: CHEBI:33570 ! benzenediols

[Term]
id: CHEBI:50202
name: naringenin
def: "A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'." []
is_a: CHEBI:140331 ! 4'-hydroxyflavanones
is_a: CHEBI:38739 ! trihydroxyflavanone

[Term]
id: CHEBI:50205
name: 3,4-dihydroxybenzaldehyde
is_a: CHEBI:50196 ! dihydroxybenzaldehyde

[Term]
id: CHEBI:50211
name: retinol
def: "A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraen-1-ol substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134394 ! primary allylic alcohol
is_a: CHEBI:26537 ! retinoid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:50218
name: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
def: "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*)." []
is_a: CHEBI:76760 ! EC 3.1.* (ester hydrolase) inhibitor

[Term]
id: CHEBI:50247
name: antidote
def: "Any protective agent counteracting or neutralizing the action of poisons." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:50248
name: hematologic agent
def: "Drug that acts on blood and blood-forming organs and those that affect the hemostatic system." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50249
name: anticoagulant
def: "An agent that prevents blood clotting." []
is_a: CHEBI:50248 ! hematologic agent

[Term]
id: CHEBI:50263
name: 2-hydroxydicarboxylic acid
def: "Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position α to the carboxy group." []
is_a: CHEBI:35692 ! dicarboxylic acid
relationship: RO:0018034 CHEBI:167114 ! is protonated form of 2-hydroxydicarboxylate(2-)

[Term]
id: CHEBI:50264
name: thiazide
def: "Heterocyclic compound with sulfur and nitrogen in the ring." []
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:50265
name: benzothiadiazine
def: "Heterocyclic compound of a ring with sulfur and two nitrogen atoms fused to a benzene ring. Members inhibit sodium-potassium-chloride symporters and are used as diuretics." []
is_a: CHEBI:50264 ! thiazide

[Term]
id: CHEBI:50266
name: prodrug
def: "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug." []
is_a: CHEBI:136859 ! pro-agent
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50267
name: protective agent
def: "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50268
name: GABA modulator
def: "A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act." []
is_a: CHEBI:38632 ! membrane transport modulator
is_a: CHEBI:51374 ! GABA agent

[Term]
id: CHEBI:50276
name: EC 5.99.1.2 (DNA topoisomerase) inhibitor
def: "A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA." []
is_a: CHEBI:70727 ! topoisomerase inhibitor

[Term]
id: CHEBI:50297
name: canonical nucleotide residue
is_a: CHEBI:50319 ! nucleotide residue

[Term]
id: CHEBI:50298
name: canonical deoxyribonucleotide residue
is_a: CHEBI:50297 ! canonical nucleotide residue

[Term]
id: CHEBI:50299
name: canonical ribonucleotide residue
is_a: CHEBI:50297 ! canonical nucleotide residue

[Term]
id: CHEBI:50305
name: podophyllotoxin
def: "An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of <em>Podophyllum</em> species and is used for the topical treatment of genital warts." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25036 ! lignan
is_a: CHEBI:50307 ! furonaphthodioxole
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50176 ! has role keratolytic drug
relationship: RO:0000087 CHEBI:61951 ! has role microtubule-destabilising agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:50307
name: furonaphthodioxole
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:38163 ! organic heterotetracyclic compound

[Term]
id: CHEBI:50308
name: cytidine 5'-monophosphate residue
def: "A canonical ribonucleotide residue derived from cytidine 5'-monophosphate" []
is_a: CHEBI:50299 ! canonical ribonucleotide residue
relationship: RO:0018034 CHEBI:82748 ! is protonated form of cytidine 5'-monophosphate(1-) residue
relationship: RO:0018037 CHEBI:17361 ! is substitutent group from cytidine 5'-monophosphate

[Term]
id: CHEBI:50312
name: onium compound
is_a: CHEBI:37577 ! heteroatomic molecular entity

[Term]
id: CHEBI:50313
name: onium cation
def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." []
is_a: CHEBI:50312 ! onium compound

[Term]
id: CHEBI:50314
name: fluoronium
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:29228 ! is protonated form of hydrogen fluoride

[Term]
id: CHEBI:50315
name: chloronium
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:17883 ! is protonated form of hydrogen chloride

[Term]
id: CHEBI:50316
name: bromonium
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:47266 ! is protonated form of hydrogen bromide

[Term]
id: CHEBI:50317
name: iodonium
is_a: CHEBI:50313 ! onium cation
relationship: RO:0018034 CHEBI:43451 ! is protonated form of hydrogen iodide

[Term]
id: CHEBI:50319
name: nucleotide residue
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:50320
name: nucleoside residue
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:50325
name: proteinogenic amino-acid side-chain group
def: "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." []
is_a: CHEBI:33249 ! organyl group

[Term]
id: CHEBI:50326
name: sulfanylmethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50327
name: selanylmethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50329
name: 2-carboxyethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50330
name: 2-amino-2-oxoethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50331
name: 3-amino-3-oxopropyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50334
name: pyridinium ion
is_a: CHEBI:25697 ! organic cation

[Term]
id: CHEBI:50335
name: organic nitrogen anion
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:50336
name: 4-hydroxybenzyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50337
name: 1H-indol-3-ylmethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50338
name: 1H-imidazol-4-ylmethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50339
name: 4-aminobutyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group
relationship: RO:0018037 CHEBI:43799 ! is substitutent group from butan-1-amine

[Term]
id: CHEBI:50340
name: 3-carbamimidamidopropyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50341
name: 1-hydroxyethyl group
is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group

[Term]
id: CHEBI:50344
name: avermectin
def: "Any of the macrolides obtained as fermentation products from the bacterium <em>Streptomyces avermitilis</em> and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25106 ! macrolide
is_a: CHEBI:59779 ! cyclic ketal
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:50351
name: cyclopropanecarboxylate ester
def: "A carboxylic ester resulting from the formal condensation of the hydroxy group of an alcohol or phenol with the carboxy group of cyclopropanecarboxylic acid or its substituted derivatives." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:51454 ! cyclopropanes
relationship: RO:0018038 CHEBI:23500 ! has functional parent cyclopropanecarboxylic acid

[Term]
id: CHEBI:50356
name: organic iodide salt
is_a: CHEBI:24858 ! iodide salt
is_a: CHEBI:51069 ! organic halide salt

[Term]
id: CHEBI:50358
name: pantoprazole(1-)
is_a: CHEBI:22715 ! benzimidazoles
relationship: RO:0018033 CHEBI:7915 ! is deprotonated form of pantoprazole

[Term]
id: CHEBI:50366
name: 6-methylprednisolone
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0018038 CHEBI:8378 ! has functional parent prednisolone

[Term]
id: CHEBI:50367
name: taxane diterpenoid
is_a: CHEBI:23849 ! diterpenoid
relationship: RO:0018040 CHEBI:36064 ! has parent hydride taxane

[Term]
id: CHEBI:50370
name: parasympatholytic
def: "Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists." []
is_a: CHEBI:48873 ! cholinergic antagonist

[Term]
id: CHEBI:50378
name: nitisinone
def: "A cyclohexanone that is cyclohexane-1,3-dione substituted at position 2 by a 2-nitro-4-(trifluoromethyl)benzoyl group. It is used in the treatment of hereditary tyrosinemia type 1." []
is_a: CHEBI:23482 ! cyclohexanones
is_a: CHEBI:38321 ! mesotrione
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes

[Term]
id: CHEBI:50382
name: EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor
def: "An  EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the activity of ceramide glucosyltransferase (EC 2.4.1.80)." []
is_a: CHEBI:76789 ! EC 2.4.1.* (hexosyltransferase) inhibitor

[Term]
id: CHEBI:50386
name: cysteamine bitartrate
is_a: CHEBI:29256 ! thiol
is_a: CHEBI:50562 ! tartrate salt
relationship: BFO:0000051 CHEBI:15193 ! has part DL-tartrate(2-)

[Term]
id: CHEBI:50390
name: EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
def: "An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2." []
is_a: CHEBI:76866 ! EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor

[Term]
id: CHEBI:50393
name: warfarin(1-)
def: "A racemate comprising equal amounts of (<i>R</i>)- and (<i>S</i>)-warfarin(1−)." []
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:87743 ! has part (R)-warfarin(1-)
relationship: BFO:0000051 CHEBI:87744 ! has part (S)-warfarin(1-)
relationship: RO:0018033 CHEBI:10033 ! is deprotonated form of warfarin

[Term]
id: CHEBI:50394
name: organic potassium salt
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:26218 ! potassium salt

[Term]
id: CHEBI:50401
name: cholestanoid
def: "Any steroid based on a cholestane skeleton and its derivatives." []
is_a: CHEBI:35341 ! steroid
relationship: RO:0018040 CHEBI:35516 ! has parent hydride cholestane

[Term]
id: CHEBI:50402
name: androstanoid
def: "Any steroid based on an  androstane skeleton and its derivatives." []
is_a: CHEBI:35341 ! steroid
relationship: RO:0018040 CHEBI:35509 ! has parent hydride androstane

[Term]
id: CHEBI:50403
name: ergostanoid
is_a: CHEBI:35341 ! steroid
relationship: RO:0018040 CHEBI:35512 ! has parent hydride ergostane

[Term]
id: CHEBI:50404
name: lipoprotein cholesterol
def: "Cholesterol esters and free cholesterol which are contained in or bound to lipoproteins." []
is_a: CHEBI:50401 ! cholestanoid

[Term]
id: CHEBI:50406
name: probe
def: "A role played by a molecular entity used to study the microscopic environment." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:50407
name: acid-base indicator
def: "An acid or base which exhibits a colour change on neutralization by the basic or acidic titrant at or near the equivalence point of a titration." []
is_a: CHEBI:50410 ! colour indicator

[Term]
id: CHEBI:50408
name: visual indicator
def: "Anything used in a scientific experiment that gives a visual change to indicate the presence of a substance or quality, change in a body, etc." []
is_a: CHEBI:47867 ! indicator

[Term]
id: CHEBI:50410
name: colour indicator
is_a: CHEBI:50408 ! visual indicator

[Term]
id: CHEBI:50411
name: one-colour indicator
def: "A colour indicator that is colourless on one side of the transition interval." []
is_a: CHEBI:50410 ! colour indicator

[Term]
id: CHEBI:50412
name: two-colour indicator
def: "A colour indicator that possesses a different colour on each side of the transition interval." []
is_a: CHEBI:50410 ! colour indicator

[Term]
id: CHEBI:50413
name: hydroxyaldehyde
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:50414
name: methylpyridine
is_a: CHEBI:26421 ! pyridines

[Term]
id: CHEBI:50415
name: 2-methylpyridine
def: "A methylpyridine carrying a methyl substituent at position 2." []
synonym: "2-Methylpyridine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:50414 ! methylpyridine

[Term]
id: CHEBI:50424
name: acrylate ester
is_a: CHEBI:51702 ! enoate ester

[Term]
id: CHEBI:50427
name: platelet aggregation inhibitor
def: "A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system." []
is_a: CHEBI:50248 ! hematologic agent

[Term]
id: CHEBI:50441
name: N-substituted diamine
is_a: CHEBI:23666 ! diamine

[Term]
id: CHEBI:50448
name: naphthylamine
def: "A primary arylamine that is naphthalene substituted by an amino group at unspecified position." []
is_a: CHEBI:38034 ! aminonaphthalene
is_a: CHEBI:50471 ! primary arylamine

[Term]
id: CHEBI:50450
name: 1-naphthylamine
def: "A naphthylamine that is naphthalene substituted by an amino group at position 1." []
is_a: CHEBI:50448 ! naphthylamine
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite

[Term]
id: CHEBI:50462
name: citronellol
def: "A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25409 ! monoterpenoid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:50469
name: EC 3.1.1.4 (phospholipase A2) inhibitor
def: "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of phospholipase A<small><sub>2</sub></small> (EC 3.1.1.4)." []
is_a: CHEBI:76773 ! EC 3.1.1.* (carboxylic ester hydrolase) inhibitor

[Term]
id: CHEBI:50471
name: primary arylamine
def: "A primary amine formally derived from ammonia by replacing one hydrogen atom by an aryl group. R-NH<small><sub>2</sub></small> where R is an aryl group." []
is_a: CHEBI:32877 ! primary amine
is_a: CHEBI:33860 ! aromatic amine

[Term]
id: CHEBI:50477
name: butyrate ester
def: "Any carboxylic ester where the carboxylic acid component is butyric acid." []
is_a: CHEBI:35748 ! fatty acid ester
relationship: RO:0018038 CHEBI:30772 ! has functional parent butyric acid

[Term]
id: CHEBI:50491
name: haloalkyl group
def: "A group derived from a haloalkane by removal of a hydrogen atom." []
is_a: CHEBI:33249 ! organyl group

[Term]
id: CHEBI:50492
name: thiocarbonyl compound
def: "Any compound containing the thiocarbonyl group, C=S." []
is_a: CHEBI:33261 ! organosulfur compound
relationship: BFO:0000051 CHEBI:30256 ! has part thiocarbonyl group

[Term]
id: CHEBI:50502
name: EC 2.5.1.15 (dihydropteroate synthase) inhibitor
def: "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of  dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from <em>p</em>-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate." []
is_a: CHEBI:76663 ! EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor

[Term]
id: CHEBI:50503
name: laxative
def: "An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50504
name: osmotic diuretic
def: "Compound that increase urine volume by increasing the amount of osmotically active solute in the urine. It also increases the osmolarity of plasma." []
is_a: CHEBI:35498 ! diuretic

[Term]
id: CHEBI:50505
name: sweetening agent
def: "Substance that sweeten food, beverages, medications, etc." []
is_a: CHEBI:35617 ! flavouring agent

[Term]
id: CHEBI:50509
name: potassium channel blocker
def: "An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions." []
is_a: CHEBI:50510 ! potassium channel modulator

[Term]
id: CHEBI:50510
name: potassium channel modulator
is_a: CHEBI:38632 ! membrane transport modulator

[Term]
id: CHEBI:50511
name: bipyridines
def: "Compounds containing a bipyridine group." []
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:64459 ! biaryl

[Term]
id: CHEBI:50513
name: mydriatic agent
def: "Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50514
name: vasoconstrictor agent
def: "Drug used to cause constriction of the blood vessels." []
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:50515
name: 24-hydroxycholesterol
def: "An oxysterol that is cholesterol which is substituted by a hydroxy group at position 24." []
is_a: CHEBI:1722 ! 3beta-hydroxy-Delta(5)-steroid
is_a: CHEBI:36865 ! 24-hydroxy steroid
is_a: CHEBI:53030 ! oxysterol

[Term]
id: CHEBI:50523
name: butenolide
def: "A γ-lactone that consists of a 2-furanone skeleton and its substituted derivatives." []
is_a: CHEBI:24129 ! furans
is_a: CHEBI:37581 ! gamma-lactone

[Term]
id: CHEBI:50524
name: catecholate(1-)
def: "A phenolate anion that is the conjugate base of catechol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:18135 ! is deprotonated form of catechol
relationship: RO:0018034 CHEBI:32402 ! is protonated form of catecholate(2-)

[Term]
id: CHEBI:50525
name: phenolate anion
def: "An organic anion arising from deprotonation of the OH function of a phenol compound." []
is_a: CHEBI:25696 ! organic anion

[Term]
id: CHEBI:50526
name: phenolate
def: "A phenolate anion that is the conjugate base of phenol obtained by deprotonation of the OH group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:15882 ! is deprotonated form of phenol

[Term]
id: CHEBI:50527
name: arsenic oxide
is_a: CHEBI:22632 ! arsenic molecular entity

[Term]
id: CHEBI:50533
name: protein denaturant
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:50536
name: phosphorus coordination entity
is_a: CHEBI:26082 ! phosphorus molecular entity
is_a: CHEBI:36562 ! main-group coordination entity

[Term]
id: CHEBI:50539
name: thiolate anion
is_a: CHEBI:84291 ! organic sulfur anion

[Term]
id: CHEBI:50562
name: tartrate salt
def: "A salt of the organic compound tartaric acid." []
is_a: CHEBI:24868 ! organic salt

[Term]
id: CHEBI:50566
name: nitric oxide donor
def: "An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide." []
is_a: CHEBI:17891 ! donor

[Term]
id: CHEBI:50569
name: isobutyl acetate
def: "The acetate ester of isobutanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018038 CHEBI:46645 ! has functional parent isobutanol

[Term]
id: CHEBI:50582
name: alkenyl alcohol
def: "Any aliphatic alcohol in which the carbon chain contains one or more olefinic bonds." []
is_a: CHEBI:2571 ! aliphatic alcohol
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:50584
name: alkyl alcohol
def: "An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position." []
is_a: CHEBI:2571 ! aliphatic alcohol

[Term]
id: CHEBI:506227
name: N-acetyl-D-glucosamine
def: "The <small>D</small> isomer of <em>N</em>-acetylglucosamine." []
is_a: CHEBI:21601 ! N-acetyl-D-hexosamine
is_a: CHEBI:59640 ! N-acetylglucosamine
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:50629
name: cyclooxygenase 2 inhibitor
def: "A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2." []
is_a: CHEBI:35544 ! EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor

[Term]
id: CHEBI:5063
name: fipronil
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-fipronil." []
is_a: CHEBI:39090 ! phenylpyrazole insecticide
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83395 ! has part (R)-fipronil
relationship: BFO:0000051 CHEBI:83396 ! has part (S)-fipronil
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38999 ! has role GABA-gated chloride channel antagonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:50630
name: cyclooxygenase 1 inhibitor
def: "A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1." []
is_a: CHEBI:35544 ! EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor

[Term]
id: CHEBI:50631
name: nitronaphthalene
def: "A nitroarene that is  naphthalene substituted by at least one nitro group." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:51132 ! nitroarene
relationship: RO:0018040 CHEBI:16482 ! has parent hydride naphthalene

[Term]
id: CHEBI:50632
name: mononitronaphthalene
def: "A nitronaphthalene carrying a single nitro group at unspecified position." []
is_a: CHEBI:50631 ! nitronaphthalene

[Term]
id: CHEBI:50635
name: EC 3.5.1.5 (urease) inhibitor
def: "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis." []
is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor

[Term]
id: CHEBI:50637
name: 2-nitronaphthalene
def: "A mononitronaphthalene carrying a nitro group at position 2." []
is_a: CHEBI:50632 ! mononitronaphthalene

[Term]
id: CHEBI:50643
name: EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor
def: "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dimethylallyl<i>trans</i>transferase (EC 2.5.1.1)." []
is_a: CHEBI:76663 ! EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor

[Term]
id: CHEBI:50646
name: bone density conservation agent
def: "An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50647
name: alendronate(1-)
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:2567 ! is deprotonated form of alendronic acid

[Term]
id: CHEBI:50648
name: 9-cis-retinoic acid
def: "A retinoic acid in which the exocyclic double bonds have 7<i>E</i>,9<i>Z</i>,11<i>E</i>,13<i>E</i> geometry." []
is_a: CHEBI:26536 ! retinoic acid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50176 ! has role keratolytic drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:63794 ! has role retinoid X receptor agonist
relationship: RO:0018034 CHEBI:78630 ! is protonated form of 9-cis-retinoate

[Term]
id: CHEBI:50658
name: ampicillin(1-)
is_a: CHEBI:51356 ! penicillinate anion
relationship: RO:0018033 CHEBI:28971 ! is deprotonated form of ampicillin

[Term]
id: CHEBI:50659
name: dronedarone
def: "A member of the class of  1-benzofurans used for the treatment of  cardiac arrhythmias." []
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38830 ! 1-benzofurans
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:50667
name: mercaptopurine
def: "A member of the class of purines that is 6,7-dihydro-1<em>H</em>-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26401 ! purines
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018036 CHEBI:2208 ! is tautomer of purine-6-thiol

[Term]
id: CHEBI:50671
name: antithyroid drug
def: "A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:50673
name: methimazole
def: "A member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen which is attached to a nitrogen." []
synonym: "1-METHYL-1,3-DIHYDRO-2H-IMIDAZOLE-2-THIONE" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:139340 ! 1,3-dihydroimidazole-2-thiones
relationship: RO:0000087 CHEBI:50671 ! has role antithyroid drug

[Term]
id: CHEBI:50680
name: methotrexate(1-)
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:44185 ! is deprotonated form of methotrexate
relationship: RO:0018034 CHEBI:50681 ! is protonated form of methotrexate(2-)

[Term]
id: CHEBI:50681
name: methotrexate(2-)
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0018033 CHEBI:50680 ! is deprotonated form of methotrexate(1-)

[Term]
id: CHEBI:50683
name: EC 1.5.1.3 (dihydrofolate reductase) inhibitor
def: "An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3)." []
is_a: CHEBI:73913 ! antifolate
is_a: CHEBI:76863 ! EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:50684
name: cross-linking reagent
def: "A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified." []
is_a: CHEBI:33893 ! reagent

[Term]
id: CHEBI:50685
name: antitrichomonal drug
def: "A drug used to treat trichomonas infections." []
is_a: CHEBI:35820 ! antiprotozoal drug

[Term]
id: CHEBI:50686
name: atorvastatin calcium
def: "An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51031 ! organic calcium salt
is_a: CHEBI:62733 ! aromatic amide
relationship: BFO:0000051 CHEBI:50690 ! has part atorvastatin(1-)
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:50689
name: reproductive control drug
def: "A substance used either in the prevention or facilitation of pregnancy." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50690
name: atorvastatin(1-)
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:39548 ! is deprotonated form of atorvastatin

[Term]
id: CHEBI:50691
name: abortifacient
def: "A chemical substance that interrupts pregnancy after implantation." []
is_a: CHEBI:50689 ! reproductive control drug

[Term]
id: CHEBI:50694
name: minocycline
def: "A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5." []
synonym: "(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE" EXACT [PDBeChem]
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:26895 ! tetracyclines
is_a: CHEBI:48132 ! tetracenomycin
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0018034 CHEBI:71337 ! is protonated form of minocycline(1-)
relationship: RO:0018036 CHEBI:77906 ! is tautomer of minocycline zwitterion

[Term]
id: CHEBI:50696
name: EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
def: "An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129)." []
is_a: CHEBI:76789 ! EC 2.4.1.* (hexosyltransferase) inhibitor

[Term]
id: CHEBI:50699
name: oligosaccharide
def: "A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues." []
is_a: CHEBI:16646 ! carbohydrate
is_a: CHEBI:167559 ! glycan

[Term]
id: CHEBI:50729
name: mitoxantrone
def: "A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37484 ! dihydroxyanthraquinone
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent

[Term]
id: CHEBI:50730
name: montelukast
is_a: CHEBI:22327 ! aliphatic sulfide
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:26513 ! quinolines
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:49159 ! has role leukotriene antagonist
relationship: RO:0000087 CHEBI:49167 ! has role anti-asthmatic drug
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018034 CHEBI:49165 ! is protonated form of montelukast(1-)

[Term]
id: CHEBI:50733
name: nutraceutical
def: "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50739
name: estrogen receptor modulator
def: "A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:507393
name: taurine zwitterion
def: "The zwitterion formed from taurine by transfer of a proton from the sulfonyl to the amino group.  It is the major species existing at physiological pH." []
is_a: CHEBI:27369 ! zwitterion
relationship: RO:0018036 CHEBI:15891 ! is tautomer of taurine

[Term]
id: CHEBI:50744
name: citrate salt
def: "A salt of citric acid." []
is_a: CHEBI:24868 ! organic salt

[Term]
id: CHEBI:50745
name: progestogen
def: "A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone." []
is_a: CHEBI:50112 ! sex hormone

[Term]
id: CHEBI:50748
name: antipsoriatic
def: "A drug used to treat psoriasis." []
is_a: CHEBI:50177 ! dermatologic drug

[Term]
id: CHEBI:50750
name: EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
def: "A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands." []
is_a: CHEBI:70727 ! topoisomerase inhibitor

[Term]
id: CHEBI:50753
name: isoflavonoid
def: "Any 1-benzopyran with an aryl substituent at position 3. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds." []
is_a: CHEBI:26004 ! phenylpropanoid
is_a: CHEBI:38443 ! 1-benzopyran
is_a: CHEBI:72544 ! flavonoids

[Term]
id: CHEBI:50779
name: appetite enhancer
def: "A drug which increases appetite." []
is_a: CHEBI:50780 ! appetite regulator

[Term]
id: CHEBI:50780
name: appetite regulator
def: "An agent which regulates the physiologic mechanisms that control the appetite and food intake." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50781
name: EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
def: "An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor) inhibitor that interferes with the action of of 3-oxo-5α-steroid 4-dehydrogenase (NADP<small><sup>+</small></sup>), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5α-dihydrotestosterone." []
is_a: CHEBI:76857 ! EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:50784
name: pivalate ester
def: "A carboxylic ester of pivalic acid." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:45133 ! has functional parent pivalic acid

[Term]
id: CHEBI:50786
name: anabolic androgenic steroid
def: "A steroid hormone related to the hormone testosterone. It increases protein synthesis within cells, which results in the buildup of cellular tissue (anabolism), especially in muscles. It also has androgenic and virilizing properties." []
is_a: CHEBI:26764 ! steroid hormone
relationship: RO:0000087 CHEBI:36413 ! has role anabolic agent
relationship: RO:0000087 CHEBI:50113 ! has role androgen

[Term]
id: CHEBI:50790
name: EC 1.14.14.14 (aromatase) inhibitor
def: "An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones." []
is_a: CHEBI:76838 ! EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor

[Term]
id: CHEBI:50792
name: estrogen receptor antagonist
def: "An antagonist at the estrogen receptor." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:50795
name: nanostructure
def: "A nanometre sized object." []
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:50803
name: nanoparticle
def: "A nanosized spherical or capsule-shaped structure." []
is_a: CHEBI:50795 ! nanostructure

[Term]
id: CHEBI:50816
name: iron oxide
is_a: CHEBI:24873 ! iron molecular entity

[Term]
id: CHEBI:50817
name: iron oxide mineral
is_a: CHEBI:46725 ! oxide mineral
is_a: CHEBI:50816 ! iron oxide

[Term]
id: CHEBI:50818
name: hematite
is_a: CHEBI:50817 ! iron oxide mineral
is_a: CHEBI:50819 ! ferric oxide

[Term]
id: CHEBI:50819
name: ferric oxide
is_a: CHEBI:50816 ! iron oxide

[Term]
id: CHEBI:50822
name: iron oxide nanoparticle
def: "A nanoparticle consisting of an iron oxide." []
is_a: CHEBI:50816 ! iron oxide
is_a: CHEBI:52855 ! inorganic nanoparticle

[Term]
id: CHEBI:50826
name: silver nanoparticle
def: "A nanoparticle consisting of silver atoms." []
is_a: CHEBI:33966 ! elemental silver
is_a: CHEBI:52855 ! inorganic nanoparticle

[Term]
id: CHEBI:50830
name: fluorinated steroid
def: "A steroid which is substituted with one or more fluorine atoms in any position." []
is_a: CHEBI:35341 ! steroid
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:50834
name: cadmium selenide
is_a: CHEBI:22978 ! cadmium molecular entity

[Term]
id: CHEBI:50835
name: cadmium selenide nanoparticle
is_a: CHEBI:50834 ! cadmium selenide
is_a: CHEBI:52855 ! inorganic nanoparticle

[Term]
id: CHEBI:50837
name: estrogen antagonist
def: "A compound which inhibits or antagonises the biosynthesis or actions of estrogens." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:50842
name: norflurazon
def: "A pyridazinone that is pyridazin-3(2<em>H</em>)-one which is substituted at positions 2, 4, and 5 by <em>m</em>-(trifluoromethyl)phenyl, chloro, and methylamino groups, respectively. A pre-emergence herbicide used to control grasses and broad-leafed weeds in a variety of crops. Not approved for use within the European Union." []
is_a: CHEBI:26414 ! pyridazinone
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:138208 ! has role carotenoid biosynthesis inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:50843
name: antimineralocorticoid
def: "A compound which inhibits or antagonizes the biosynthesis or actions of mineralocorticoids, a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:50844
name: aldosterone antagonist
def: "A compound which inhibits or antagonizes the biosynthesis or actions of aldosterone." []
is_a: CHEBI:50843 ! antimineralocorticoid

[Term]
id: CHEBI:50845
name: doxycycline
def: "Tetracycline in which the 5β-hydrogen is replaced by a hydroxy group, while the 6α-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis." []
synonym: "(4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE" EXACT [PDBeChem]
is_a: CHEBI:26895 ! tetracyclines
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:50846
name: immunomodulator
def: "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:50847
name: immunological adjuvant
def: "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity." []
is_a: CHEBI:50846 ! immunomodulator
is_a: CHEBI:60809 ! adjuvant

[Term]
id: CHEBI:50855
name: antiatherogenic agent
def: "A cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries. Compare with <a href=\"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:145947\" target=\"_blank\">antiatherosclerotic agent</a>." []
is_a: CHEBI:35554 ! cardiovascular drug

[Term]
id: CHEBI:50856
name: 2-furoate ester
def: "Any carboxylic ester where the carboxylic acid component is 2-furoic acid." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:30845 ! has functional parent 2-furoic acid

[Term]
id: CHEBI:50857
name: anti-allergic agent
def: "A drug used to treat allergic reactions." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50858
name: corticosteroid
def: "A natural or synthetic analogue of the hormones secreted by the adrenal gland." []
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:50860
name: organic molecular entity
def: "Any molecular entity that contains carbon." []
is_a: CHEBI:33582 ! carbon group molecular entity
relationship: BFO:0000051 CHEBI:27594 ! has part carbon atom

[Term]
id: CHEBI:50861
name: treprostinil
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:38032 ! carbotricyclic compound
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:55347 ! has role vitamin K antagonist
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite

[Term]
id: CHEBI:50864
name: insulin-sensitizing drug
def: "An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma)." []
is_a: CHEBI:35526 ! hypoglycemic agent
is_a: CHEBI:48705 ! agonist
is_a: CHEBI:70781 ! PPAR modulator

[Term]
id: CHEBI:50887
name: haloarene
def: "A compound derived from an arene by replacing a hydrogen atom with a halogen atom." []
is_a: CHEBI:24472 ! halohydrocarbon

[Term]
id: CHEBI:50893
name: azaarene
is_a: CHEBI:33833 ! heteroarene
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:50900
name: dextronorgestrel
def: "The (+)-enantiomer of norgestrel." []
is_a: CHEBI:231594 ! 17-ethynyl-17-hydroxy-18a-homoestr-4-en-3-one
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
relationship: RO:0018039 CHEBI:6443 ! is enantiomer of levonorgestrel

[Term]
id: CHEBI:50902
name: genotoxin
def: "A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:50903
name: carcinogenic agent
def: "A role played by a chemical compound which is known to  induce a process of carcinogenesis  by corrupting  normal cellular pathways, leading to the acquistion of tumoral capabilities." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:50904
name: allergen
def: "A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:50905
name: teratogenic agent
def: "A role played by a chemical compound  in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:50906
name: role
def: "A role is particular behaviour which a material entity may exhibit." []

[Term]
id: CHEBI:50908
name: hepatotoxic agent
def: "A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:50909
name: nephrotoxic agent
def: "A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:50910
name: neurotoxin
def: "A poison that interferes with the functions of the nervous system." []
is_a: CHEBI:52209 ! aetiopathogenetic role
is_a: CHEBI:64909 ! poison

[Term]
id: CHEBI:50912
name: cardiotoxic agent
def: "A role played by a chemical compound exhibiting itself through the ability to induce damage to the heart and cardiomyocytes." []
is_a: CHEBI:52209 ! aetiopathogenetic role

[Term]
id: CHEBI:50913
name: fixative
def: "Any compound used for the purpose of preserving biological tissues from decay in such a way as to allow for the preparation of thin, stained sections for subsequent histological study." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:50914
name: EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
def: "An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol." []
is_a: CHEBI:50916 ! lipid kinase inhibitor
is_a: CHEBI:76881 ! EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor

[Term]
id: CHEBI:50916
name: lipid kinase inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of lipid kinases." []
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:50919
name: antiemetic
def: "A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50921
name: fumarate salt
def: "An organic salt derived from fumaric acid." []
is_a: CHEBI:24868 ! organic salt

[Term]
id: CHEBI:50924
name: sorafenib
def: "A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 4-chloro-3-trifluorophenyl group while the other is substituted by a phenyl group which, in turn, is substituted at the <em>para</em> position by a [2-(methylcarbamoyl)pyridin-4-yl]oxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134043 ! phenylureas
is_a: CHEBI:25529 ! pyridinecarboxamide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50925 ! has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor

[Term]
id: CHEBI:50925
name: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine." []
is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor

[Term]
id: CHEBI:50926
name: angiogenesis modulating agent
def: "An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:50928
name: sorafenib tosylate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:64382 ! organosulfonate salt
relationship: BFO:0000051 CHEBI:50924 ! has part sorafenib
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:50929
name: aziridinium
is_a: CHEBI:37949 ! azacycloalkane
is_a: CHEBI:50946 ! aziridinium ion
relationship: RO:0018034 CHEBI:30969 ! is protonated form of aziridine

[Term]
id: CHEBI:50946
name: aziridinium ion
def: "Compounds containing an aziridine ring that contains a quaternary nitrogen atom." []
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:50949
name: serotonin uptake inhibitor
def: "A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent." []
is_a: CHEBI:48278 ! serotonergic drug

[Term]
id: CHEBI:50955
name: arsonic acids
def: "Arsonic acid and its As-hydrocarbyl derivatives." []
is_a: CHEBI:33407 ! arsenic oxoacid

[Term]
id: CHEBI:50956
name: organoarsonic acid anion
is_a: CHEBI:33406 ! organoarsenic compound

[Term]
id: CHEBI:50967
name: non-covalently-bound molecular entity
def: "Systems consisting of two or more molecular entities held together by non-covalent interactions." []
is_a: CHEBI:36357 ! polyatomic entity

[Term]
id: CHEBI:5097
name: fluazifop-butyl
def: "A racemate that is the butyl ester of fluazifop. It is used as a post-emergence herbicide for the control grass weeds in various broad-leaved crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:132964 ! has part fluazifop-P-butyl
relationship: BFO:0000051 CHEBI:132965 ! has part (S)-fluazifop-butyl
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor

[Term]
id: CHEBI:5098
name: flucloxacillin
def: "A penicillin compound having a 6β-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido] side-chain." []
is_a: CHEBI:16670 ! peptide
is_a: CHEBI:88187 ! penicillin allergen
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0018034 CHEBI:52037 ! is protonated form of flucloxacillin(1-)

[Term]
id: CHEBI:50981
name: secondary aliphatic amine
is_a: CHEBI:32863 ! secondary amine
relationship: RO:0018033 CHEBI:58855 ! is deprotonated form of secondary aliphatic ammonium ion

[Term]
id: CHEBI:50990
name: thiazolidinediones
def: "A thiadiazolidine in which the 1,3-thiazolidine ring is substituted by two oxo groups." []
is_a: CHEBI:35622 ! thiazolidines

[Term]
id: CHEBI:50994
name: primary amino compound
def: "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." []
is_a: CHEBI:50047 ! organic amino compound
relationship: RO:0018033 CHEBI:65296 ! is deprotonated form of primary ammonium ion

[Term]
id: CHEBI:50995
name: secondary amino compound
def: "A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups." []
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:50996
name: tertiary amino compound
def: "A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups." []
is_a: CHEBI:50047 ! organic amino compound
relationship: RO:0018033 CHEBI:137982 ! is deprotonated form of tertiary ammonium ion

[Term]
id: CHEBI:51002
name: bis(eta(5)-cyclopentadienyl)metal(II)
is_a: CHEBI:33963 ! metallocene

[Term]
id: CHEBI:51005
name: ferrocenes
def: "Compounds containing a ferrocene skeleton." []
is_a: CHEBI:33892 ! iron coordination entity
is_a: CHEBI:33963 ! metallocene

[Term]
id: CHEBI:51026
name: macrocycle
def: "A cyclic compound containing nine or more atoms as part of the cyclic system." []
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:51029
name: nedocromil(2-)
is_a: CHEBI:38716 ! carboxylic acid dianion
relationship: RO:0018033 CHEBI:7492 ! is deprotonated form of nedocromil

[Term]
id: CHEBI:51031
name: organic calcium salt
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:35156 ! calcium salt

[Term]
id: CHEBI:51039
name: dopamine uptake inhibitor
def: "A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake." []
is_a: CHEBI:48560 ! dopaminergic agent

[Term]
id: CHEBI:51041
name: acamprosate
def: "An  organosulfonic acid that is propane-1-sulfonic acid substituted by an acetylamino group at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:33551 ! organosulfonic acid
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35942 ! has role neurotransmitter agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:51050
name: titanium dioxide nanoparticle
def: "A nanoparticle consisting of titanium dioxide." []
is_a: CHEBI:134441 ! titanium oxide nanoparticle
is_a: CHEBI:32234 ! titanium dioxide

[Term]
id: CHEBI:51057
name: 3-phenylpropionate
def: "A monocarboxylic acid anion that is the conjugate base of 3-phenylpropionic acid, obtained by deprotonation of the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28631 ! is deprotonated form of 3-phenylpropionic acid

[Term]
id: CHEBI:51060
name: hormone agonist
def: "A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." []
is_a: CHEBI:48705 ! agonist
is_a: CHEBI:51061 ! hormone receptor modulator

[Term]
id: CHEBI:51061
name: hormone receptor modulator
def: "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." []
is_a: CHEBI:90710 ! receptor modulator

[Term]
id: CHEBI:51067
name: tetraphenes
is_a: CHEBI:33836 ! benzenoid aromatic compound

[Term]
id: CHEBI:51069
name: organic halide salt
is_a: CHEBI:24868 ! organic salt

[Term]
id: CHEBI:51076
name: antifouling biocide
def: "A compound that inhibits the growth of marine organisms." []
is_a: CHEBI:25944 ! pesticide

[Term]
id: CHEBI:51080
name: nitrate ester
def: "Any member of the class of nitrates resulting from the esterification of nitric acid with an alcohol." []
is_a: CHEBI:36963 ! organooxygen compound
is_a: CHEBI:51081 ! nitrates

[Term]
id: CHEBI:51081
name: nitrates
def: "Salts or esters of nitric acid." []
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: RO:0018038 CHEBI:48107 ! has functional parent nitric acid

[Term]
id: CHEBI:51082
name: nitrate salt
is_a: CHEBI:24866 ! salt
relationship: BFO:0000051 CHEBI:17632 ! has part nitrate

[Term]
id: CHEBI:51084
name: inorganic nitrate salt
is_a: CHEBI:24839 ! inorganic salt
is_a: CHEBI:51082 ! nitrate salt

[Term]
id: CHEBI:51086
name: chemical role
def: "A role played by the molecular entity or part thereof within a chemical context." []
is_a: CHEBI:50906 ! role

[Term]
id: CHEBI:51119
name: tricyclic hydrocarbon
is_a: CHEBI:33666 ! polycyclic hydrocarbon

[Term]
id: CHEBI:51121
name: fluorescent dye
is_a: CHEBI:37958 ! dye

[Term]
id: CHEBI:51125
name: s-indacenes
def: "Molecular entities containing an <em>s</em>-indacene skeleton." []
is_a: CHEBI:46834 ! indacenes

[Term]
id: CHEBI:51129
name: nitrohydrocarbon
def: "A <em>C</em>-nitro compound that is a hydrocarbon in which one or more of the hydrogens has been replaced by nitro groups." []
is_a: CHEBI:35716 ! C-nitro compound

[Term]
id: CHEBI:51132
name: nitroarene
def: "A nitrohydrocarbon that consists of an arene skeleton substituted by one or more nitro groups at unspecified positions." []
is_a: CHEBI:51129 ! nitrohydrocarbon

[Term]
id: CHEBI:51143
name: nitrogen molecular entity
is_a: CHEBI:33302 ! pnictogen molecular entity
relationship: BFO:0000051 CHEBI:25555 ! has part nitrogen atom

[Term]
id: CHEBI:51144
name: nitrogen group
is_a: CHEBI:24433 ! group

[Term]
id: CHEBI:51149
name: xanthones
def: "Any member of the class of  xanthenes based on a xanthone skeleton." []
is_a: CHEBI:38835 ! xanthenes
is_a: CHEBI:3992 ! cyclic ketone

[Term]
id: CHEBI:5115
name: monofluorobenzene
def: "The simplest member of the class of  monofluorobenzenes that is benzene carrying a single fluoro substituent." []
is_a: CHEBI:83575 ! monofluorobenzenes

[Term]
id: CHEBI:51151
name: dipolar compound
def: "An  organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." []
is_a: CHEBI:72695 ! organic molecule

[Term]
id: CHEBI:51175
name: organoaluminium compound
def: "A compound containing at least one carbon-aluminium bond." []
is_a: CHEBI:25707 ! organometallic compound

[Term]
id: CHEBI:51177
name: antitussive
def: "An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with  <em>expectorants</em>, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and <em>mucolytics</em>, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:5118
name: fluoxetine
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:86991 ! has part (R)-fluoxetine
relationship: BFO:0000051 CHEBI:86992 ! has part (S)-fluoxetine
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:36810 ! has functional parent (trifluoromethyl)benzene

[Term]
id: CHEBI:51214
name: diamminedichloroplatinum
is_a: CHEBI:33862 ! platinum coordination entity

[Term]
id: CHEBI:51217
name: fluorochrome
def: "A fluorescent dye used to stain biological specimens." []
is_a: CHEBI:51121 ! fluorescent dye

[Term]
id: CHEBI:51256
name: amoxicillin(1-)
is_a: CHEBI:51356 ! penicillinate anion
relationship: RO:0018033 CHEBI:2676 ! is deprotonated form of amoxicillin

[Term]
id: CHEBI:51269
name: acenes
def: "Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives." []
is_a: CHEBI:33836 ! benzenoid aromatic compound

[Term]
id: CHEBI:51270
name: tetracenes
def: "Compounds containing a tetracene skeleton." []
is_a: CHEBI:51269 ! acenes

[Term]
id: CHEBI:51276
name: thioureas
def: "Compounds of general formula RR'NC(=S)NR''R'''." []
is_a: CHEBI:50492 ! thiocarbonyl compound

[Term]
id: CHEBI:51277
name: thioester
def: "A compound of general formula RC(=O)SR'. Compare with thionoester, RC(=S)OR'." []
is_a: CHEBI:26959 ! thiocarboxylic ester
is_a: CHEBI:36586 ! carbonyl compound

[Term]
id: CHEBI:51280
name: S-methyl thioacetate
is_a: CHEBI:51277 ! thioester
relationship: RO:0018038 CHEBI:16555 ! has functional parent ethanethioic S-acid

[Term]
id: CHEBI:51285
name: acenoquinone
def: "Quinones containing an acene fused ring system." []
is_a: CHEBI:36141 ! quinone
is_a: CHEBI:51269 ! acenes

[Term]
id: CHEBI:51286
name: tetracenequinones
is_a: CHEBI:51285 ! acenoquinone
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:51307
name: diester
def: "A diester is a compound containing two ester groups." []
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:51308
name: dinitrile
def: "A dinitrile is a compound containing two nitrile groups." []
is_a: CHEBI:18379 ! nitrile

[Term]
id: CHEBI:51311
name: bromoethene
is_a: CHEBI:51313 ! monohaloethene
is_a: CHEBI:51328 ! bromoalkene

[Term]
id: CHEBI:51313
name: monohaloethene
def: "A haloethene in which only one of the hydrogen atoms in ethene is replaced by a halogen atom." []
is_a: CHEBI:51316 ! haloethene

[Term]
id: CHEBI:51314
name: fluoroethene
is_a: CHEBI:138675 ! gas molecular entity
is_a: CHEBI:51313 ! monohaloethene

[Term]
id: CHEBI:51316
name: haloethene
def: "A compound derived from ethene by replacing one or more hydrogen atoms with halogen atoms." []
is_a: CHEBI:5610 ! haloalkene
relationship: RO:0018040 CHEBI:18153 ! has parent hydride ethene

[Term]
id: CHEBI:51324
name: vinylarene
def: "A vinyl-substituted arene." []
is_a: CHEBI:33658 ! arene

[Term]
id: CHEBI:51328
name: bromoalkene
def: "A compound derived from an alkene by replacing a hydrogen atom with a bromine atom." []
is_a: CHEBI:22926 ! bromohydrocarbon
is_a: CHEBI:5610 ! haloalkene

[Term]
id: CHEBI:51336
name: metal sulfate
def: "Sulfate salts where the cation is a metal ion." []
is_a: CHEBI:24840 ! inorganic sulfate salt

[Term]
id: CHEBI:51337
name: organic sulfate salt
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:35175 ! sulfate salt

[Term]
id: CHEBI:51339
name: adamantanes
def: "Compounds containing an adamantane skeleton." []
is_a: CHEBI:35294 ! carbopolycyclic compound

[Term]
id: CHEBI:5134
name: fluticasone
def: "A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36834 ! 3-hydroxy steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:50830 ! fluorinated steroid
is_a: CHEBI:50858 ! corticosteroid
is_a: CHEBI:51277 ! thioester
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:49167 ! has role anti-asthmatic drug
relationship: RO:0000087 CHEBI:50113 ! has role androgen
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0018040 CHEBI:35509 ! has parent hydride androstane

[Term]
id: CHEBI:51349
name: polyamine macromolecule
def: "A macromolecule composed of units connected by imino (‒NR‒) linkages." []
synonym: "Polyamine" EXACT [KEGG_COMPOUND]
is_a: CHEBI:33839 ! macromolecule
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:5135
name: fluvalinate
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:25705 ! organochlorine insecticide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38657 ! organochlorine acaricide
is_a: CHEBI:38804 ! organofluorine insecticide
is_a: CHEBI:38806 ! organofluorine acaricide
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0000087 CHEBI:39259 ! has role pyrethroid ester acaricide
relationship: RO:0018038 CHEBI:27266 ! has functional parent valine

[Term]
id: CHEBI:51354
name: benzylpenicillin(1-)
is_a: CHEBI:51356 ! penicillinate anion
relationship: RO:0018033 CHEBI:18208 ! is deprotonated form of benzylpenicillin

[Term]
id: CHEBI:51356
name: penicillinate anion
def: "Any anion formed by loss of a proton from the carboxy group of a penicillin." []
is_a: CHEBI:47811 ! penamcarboxylate
relationship: RO:0018033 CHEBI:17334 ! is deprotonated form of penicillin

[Term]
id: CHEBI:51361
name: benzotriazines
def: "Compounds based on a fused triazine and benzene ring skeleton." []
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:51371
name: muscle relaxant
def: "A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis." []
is_a: CHEBI:51372 ! neuromuscular agent

[Term]
id: CHEBI:51372
name: neuromuscular agent
def: "A drug used for its actions on skeletal muscle." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:51373
name: GABA agonist
def: "A drug that binds to and activates γ-aminobutyric acid receptors." []
is_a: CHEBI:51374 ! GABA agent

[Term]
id: CHEBI:51374
name: GABA agent
def: "A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:5138
name: fluvoxamine
def: "An oxime <em>O</em>-ether that is benzene substituted by a (1<i>E</i>)-<em>N</em>-(2-aminoethoxy)-5-methoxypentanimidoyl group at position 1 and a trifluoromethyl group at position 4. It is a selective serotonin reuptake inhibitor that is used for the treatment of obsessive-compulsive disorder." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36815 ! 5-methoxyvalerophenone O-(2-aminoethyl)oxime
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0018038 CHEBI:36810 ! has functional parent (trifluoromethyl)benzene

[Term]
id: CHEBI:51384
name: D-ascorbic acid
is_a: CHEBI:22652 ! ascorbic acid
relationship: RO:0018039 CHEBI:29073 ! is enantiomer of L-ascorbic acid

[Term]
id: CHEBI:51396
name: dinitrobenzene
def: "Any member of the class of nitrobenzenes that consists of a benzene ring substituted by two nitro groups. A closed class." []
is_a: CHEBI:48109 ! nitrobenzenes

[Term]
id: CHEBI:51397
name: 1,3-dinitrobenzene
def: "A dinitrobenzene that is benzene disubstituted at positions 1 and 3 with nitro groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51396 ! dinitrobenzene
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:51398
name: 1,4-dinitrobenzene
def: "A dinitrobenzene carrying nitro groups at positions 1 and 4." []
is_a: CHEBI:51396 ! dinitrobenzene

[Term]
id: CHEBI:51402
name: phenylenediamine
def: "A benzene substituted with two amino groups." []
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35410 ! primary diamine

[Term]
id: CHEBI:51403
name: 1,4-phenylenediamine
def: "A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus." []
is_a: CHEBI:51402 ! phenylenediamine
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:37958 ! has role dye
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:59174 ! has role hapten

[Term]
id: CHEBI:51422
name: organodiyl group
def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." []
is_a: CHEBI:51446 ! organic divalent group

[Term]
id: CHEBI:51446
name: organic divalent group
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:51447
name: organic univalent group
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:51451
name: endothelin receptor antagonist
def: "A hormone antagonist that blocks endothelin receptors." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:51454
name: cyclopropanes
def: "Cyclopropane and its derivatives formed by substitution." []
is_a: CHEBI:33598 ! carbocyclic compound

[Term]
id: CHEBI:51455
name: cyclopropenes
def: "A carbocyclic compound that is cyclopropene and its derivatives formed by substitution." []
is_a: CHEBI:33598 ! carbocyclic compound

[Term]
id: CHEBI:51518
name: halometallate anion
def: "An anionic coordination entity where halido ligands are coordinated to a metal centre." []
is_a: CHEBI:33240 ! coordination entity
is_a: CHEBI:33273 ! polyatomic anion

[Term]
id: CHEBI:51519
name: perhalometallate anion
def: "A halometallate anion where all of the ligands coordinated to the metal atom are halido ligands." []
is_a: CHEBI:51518 ! halometallate anion

[Term]
id: CHEBI:51527
name: fluorometallate anion
def: "An anionic coordination entity where fluorido ligands are coordinated to a metal centre." []
is_a: CHEBI:51518 ! halometallate anion

[Term]
id: CHEBI:51528
name: perfluorometallate anion
def: "An anionic coordination entity where all of the ligands coordinated to the metal atom are fluorido ligands." []
is_a: CHEBI:51519 ! perhalometallate anion
is_a: CHEBI:51527 ! fluorometallate anion

[Term]
id: CHEBI:51529
name: halometallate salt
def: "A salt where the anion is a halometallate anion." []
is_a: CHEBI:24866 ! salt
relationship: BFO:0000051 CHEBI:51518 ! has part halometallate anion

[Term]
id: CHEBI:51530
name: perhalometallate salt
def: "A salt where the anion is a perhalometallate anion." []
is_a: CHEBI:51529 ! halometallate salt
relationship: BFO:0000051 CHEBI:51519 ! has part perhalometallate anion

[Term]
id: CHEBI:51531
name: perfluorometallate salt
def: "A salt where the anion is a perfluorometallate anion." []
is_a: CHEBI:51530 ! perhalometallate salt
is_a: CHEBI:51532 ! fluorometallate salt
relationship: BFO:0000051 CHEBI:51528 ! has part perfluorometallate anion

[Term]
id: CHEBI:51532
name: fluorometallate salt
def: "A salt where the anion is an fluorometallate anion." []
is_a: CHEBI:51529 ! halometallate salt
relationship: BFO:0000051 CHEBI:51527 ! has part fluorometallate anion

[Term]
id: CHEBI:51545
name: 1,2-benzoxazoles
def: "Compounds based on a fused 1,2-oxazole and benzene bicyclic ring skeleton, with the O atom positioned adjacent to one of the positions of ring fusion." []
is_a: CHEBI:51549 ! benzisoxazole

[Term]
id: CHEBI:51548
name: 1,3-benzoxazoles
def: "Compounds based on a fused 1,3-oxazole and benzene bicyclic ring skeleton." []
is_a: CHEBI:46700 ! benzoxazole

[Term]
id: CHEBI:51549
name: benzisoxazole
def: "Compounds based on a fused 1,2-oxazole and benzene bicyclic ring skeleton." []
is_a: CHEBI:46700 ! benzoxazole

[Term]
id: CHEBI:51569
name: N-acyl-amino acid
def: "A carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of an amino acid." []
is_a: CHEBI:33575 ! carboxylic acid
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:33709 ! has functional parent amino acid

[Term]
id: CHEBI:51570
name: biotins
def: "Compounds containing a biotin (5-[(3a<i>S</i>,4<i>S</i>,6a<i>R</i>)-2-oxohexahydro-1<em>H</em>-thieno[3,4-<em>d</em>]imidazol-4-yl]pentanoic acid) skeleton." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:38295 ! azabicycloalkane
is_a: CHEBI:38297 ! thiabicycloalkane
is_a: CHEBI:47857 ! ureas

[Term]
id: CHEBI:51580
name: phthalocyanines
def: "Compounds containing a phthalocyanine skeleton." []
is_a: CHEBI:36309 ! cyclic tetrapyrrole

[Term]
id: CHEBI:51584
name: metallophthalocyanines
is_a: CHEBI:33909 ! metallotetrapyrrole
is_a: CHEBI:51580 ! phthalocyanines

[Term]
id: CHEBI:51585
name: metallophthalocyanine
is_a: CHEBI:51584 ! metallophthalocyanines

[Term]
id: CHEBI:51614
name: diarylmethane
def: "Any compound containing two aryl groups connected by a single C atom." []
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:51659
name: dihydrofuran
def: "Compounds containing a mono-unsaturated furan ring skeleton." []
is_a: CHEBI:24129 ! furans

[Term]
id: CHEBI:51683
name: methoxybenzenes
def: "Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:51685
name: diborane
def: "Boranes containing only two B atoms, linked either directly by a B‒B bond or via hydrogen bridging atoms." []
is_a: CHEBI:33589 ! boranes

[Term]
id: CHEBI:51688
name: enal
def: "An α,β-unsaturated aldehyde of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒CH=O in which the aldehydic C=O function is conjugated to a C=C double bond at the α,β position." []
is_a: CHEBI:51718 ! alpha,beta-unsaturated aldehyde
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:51689
name: enone
def: "An α,β-unsaturated ketone of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒C(=O)R<small><sup>4</small></sup> (R<small><sup>4</small></sup> ≠ H) in which the C=O function is conjugated to a C=C double bond at the α,β position." []
is_a: CHEBI:51721 ! alpha,beta-unsaturated ketone
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:5169
name: fraxetin
def: "A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37912 ! hydroxycoumarin
relationship: RO:0000087 CHEBI:140602 ! has role Arabidopsis thaliana metabolite
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:51702
name: enoate ester
def: "An α,β-unsaturated carboxylic ester of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒C(=O)OR<small><sup>4</small></sup> (R<small><sup>4</small></sup> ≠ H) in which the ester C=O function is conjugated to a C=C double bond at the α,β position." []
is_a: CHEBI:51737 ! alpha,beta-unsaturated carboxylic ester
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:51718
name: alpha,beta-unsaturated aldehyde
def: "An aldehyde of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒CH=O or RC≡C‒CH=O in which the aldehydic C=O function is conjugated to an unsaturated C-C bond at the α,β position." []
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:51721
name: alpha,beta-unsaturated ketone
def: "A ketone of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒C(=O)R<small><sup>4</small></sup> (R<small><sup>4</small></sup> ≠ H) or R<small><sup>1</small></sup>C≡C‒C(=O)R<small><sup>2</small></sup> (R<small><sup>2</small></sup> ≠ H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the α,β position." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:51737
name: alpha,beta-unsaturated carboxylic ester
def: "A carboxylic ester of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒C(=O)OR<small><sup>4</small></sup> (R<small><sup>4</small></sup> ≠ H) or R<small><sup>1</small></sup>C≡C‒C(=O)OR<small><sup>2</small></sup> (R<small><sup>2</small></sup> ≠ H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the α,β position." []
is_a: CHEBI:33308 ! carboxylic ester

[Term]
id: CHEBI:51750
name: alpha,beta-unsaturated carboxylic acid amide
def: "A monocarboxylic amide of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒C(=O)NR<small><sup>4</small></sup>R<small><sup>5</small></sup>  or R<small><sup>1</small></sup>C≡C‒C(=O)NR<small><sup>2</small></sup>R<small><sup>3</small></sup> in which the amide C=O function is conjugated to an unsaturated C-C bond at the α,β position." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:51751
name: enamide
def: "An α,β-unsaturated carboxylic acid amide of general formula R<small><sup>1</small></sup>R<small><sup>2</small></sup>C=CR<small><sup>3</small></sup>‒C(=O)NR<small><sup>4</small></sup>R<small><sup>5</small></sup> in which the amide C=O function is conjugated to a C=C double bond at the α,β position." []
is_a: CHEBI:51750 ! alpha,beta-unsaturated carboxylic acid amide
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:5181
name: fucoidan
def: "A type of fucose-rich sulfated polysaccharide found in various species of brown algae, seaweed and sea-cucumbers." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37944 ! polysaccharide sulfate
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35679 ! has role antilipemic drug
relationship: RO:0000087 CHEBI:63054 ! has role osteogenesis regulator
relationship: RO:0000087 CHEBI:64933 ! has role melanin synthesis inhibitor
relationship: RO:0000087 CHEBI:67239 ! has role EC 3.2.1.20 (alpha-glucosidase) inhibitor
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite

[Term]
id: CHEBI:51851
name: ketonitrile
def: "A compound containing both ketone and nitrile functionalities." []
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:18379 ! nitrile

[Term]
id: CHEBI:51852
name: alpha-ketonitrile
def: "A ketonitrile where the ketone and nitrile functionalities are on adjacent atoms." []
is_a: CHEBI:51851 ! ketonitrile

[Term]
id: CHEBI:51856
name: methylphenidate(1+)
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:6887 ! is protonated form of methylphenidate

[Term]
id: CHEBI:51857
name: methyl (S)-phenyl[(S)-piperidin-2-yl]acetate
def: "A methyl phenyl(piperidin-2-yl)acetate in which both stereocentres have <i>S</i> configuration. It is the inactive enantiomer in the racemic drug methylphenidate." []
is_a: CHEBI:84276 ! methyl phenyl(piperidin-2-yl)acetate
relationship: RO:0018039 CHEBI:51860 ! is enantiomer of dexmethylphenidate

[Term]
id: CHEBI:51860
name: dexmethylphenidate
def: "A methyl phenyl(piperidin-2-yl)acetate in which both stereocentres have <i>R</i> configuration.  It is the active enantiomer in the racemic drug methylphenidate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:84276 ! methyl phenyl(piperidin-2-yl)acetate
relationship: RO:0000087 CHEBI:37962 ! has role adrenergic agent
relationship: RO:0018039 CHEBI:51857 ! is enantiomer of methyl (S)-phenyl[(S)-piperidin-2-yl]acetate

[Term]
id: CHEBI:51867
name: methyl ketone
def: "A ketone of formula RC(=O)CH<small><sub>3</sub></small> (R ≠ H)." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:51874
name: auramine O free base
def: "A member of the class of imines that is benzophenone imine carrying two dimethylamino substituents at positions 4 and 4'. The hydrochloride salt is the biological stain 'auramine O'" []
is_a: CHEBI:24783 ! imine
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0018033 CHEBI:87485 ! is deprotonated form of auramine O(1+)

[Term]
id: CHEBI:51915
name: indolocarbazole
def: "Compounds based upon an indolo[2,3-<em>a</em>]carbazole skeleton." []
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:51917
name: formamidines
def: "Amidines with the general formula R<small><sup>1</small></sup>N=CHNR<small><sup>2</small></sup>R<small><sup>3</small></sup> (R<small><sup>1</small></sup>, R<small><sup>2</small></sup>, R<small><sup>3</small></sup> can be H)." []
is_a: CHEBI:35359 ! carboxamidine

[Term]
id: CHEBI:51937
name: butyronitrile
def: "A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a propyl group." []
is_a: CHEBI:80291 ! aliphatic nitrile

[Term]
id: CHEBI:51958
name: organic polycyclic compound
is_a: CHEBI:33635 ! polycyclic compound
is_a: CHEBI:33832 ! organic cyclic compound

[Term]
id: CHEBI:51959
name: organic tricyclic compound
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:52023
name: hyodeoxycholic acid
def: "A member of the class of 5β-cholanic acids that is (5β)-cholan-24-oic acid substituted by α-hydroxy groups at positions 3 and 6. It is a bioactive compound extracted from Calculus bovis." []
is_a: CHEBI:131620 ! C24-steroid
is_a: CHEBI:3098 ! bile acid
is_a: CHEBI:363227 ! 6alpha,20xi-murideoxycholic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:58875 ! is protonated form of hyodeoxycholate
relationship: RO:0018038 CHEBI:16359 ! has functional parent cholic acid

[Term]
id: CHEBI:52037
name: flucloxacillin(1-)
is_a: CHEBI:51356 ! penicillinate anion
relationship: RO:0018033 CHEBI:5098 ! is deprotonated form of flucloxacillin

[Term]
id: CHEBI:52090
name: methoxide
def: "An organic anion that is the conjugate base of methanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25696 ! organic anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17790 ! is deprotonated form of methanol

[Term]
id: CHEBI:52092
name: ethoxide
def: "An organic anion that is the conjugate base of ethanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25696 ! organic anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16236 ! is deprotonated form of ethanol

[Term]
id: CHEBI:52145
name: pyrrolidinium ion
def: "The ion formed by protonating nitrogen in pyrrolidine." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:33135 ! is protonated form of pyrrolidine

[Term]
id: CHEBI:52153
name: 2-diethylaminoethanol
def: "A member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:747339 ! has role plastic light stabilizer
relationship: RO:0000087 CHEBI:747342 ! has role polymerization initiator
relationship: RO:0018038 CHEBI:16000 ! has functional parent ethanolamine
relationship: RO:0018040 CHEBI:35026 ! has parent hydride triethylamine

[Term]
id: CHEBI:52157
name: organic heteroheptacyclic compound
is_a: CHEBI:38166 ! organic heteropolycyclic compound

[Term]
id: CHEBI:52172
name: nilotinib
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug

[Term]
id: CHEBI:52206
name: biochemical role
def: "A biological role played by the molecular entity or part thereof within a biochemical context." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52208
name: biophysical role
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52209
name: aetiopathogenetic role
def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52210
name: pharmacological role
def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52211
name: physiological role
def: "A biological role relating to the normal mechanisms and their interactions within a living system." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52214
name: ligand
def: "Any molecule or ion capable of binding to a central metal atom to form coordination complexes." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:52215
name: photochemical role
def: "A  chemical role played by the molecular entity or part thereof in a photochemical process." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:52217
name: pharmaceutical
def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:52218
name: pinacyanol iodide
is_a: CHEBI:37960 ! cyanine dye
is_a: CHEBI:50356 ! organic iodide salt
relationship: BFO:0000051 CHEBI:52877 ! has part pinacyanol cation
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome

[Term]
id: CHEBI:52221
name: isothiocyanate
def: "An organosulfur compound with the general formula R‒N=C=S." []
is_a: CHEBI:33261 ! organosulfur compound
relationship: RO:0018038 CHEBI:24928 ! has functional parent isothiocyanic acid

[Term]
id: CHEBI:52242
name: 1,4-diphenylbenzene
def: "A <em>para</em>-terphenyl that consists of benzene attached to two phenyl units at positions 1 and 4 respectively." []
is_a: CHEBI:75874 ! para-terphenyl

[Term]
id: CHEBI:52261
name: rose bengal
def: "An organic potassium salt that is the dipotassium salt of 2,3,4,5-tetrachloro-6-(2,4,5,7-tetraiodo-6-hydroxy-3-oxoxanthen-9-yl)benzoic acid." []
is_a: CHEBI:37929 ! xanthene dye
is_a: CHEBI:50394 ! organic potassium salt
relationship: BFO:0000051 CHEBI:52904 ! has part rose bengal(2-)
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0018038 CHEBI:42492 ! has functional parent fluorescin

[Term]
id: CHEBI:52267
name: 7-hydroxyflavonol
def: "Any flavonol carrying a 7-hydroxy substituent." []
is_a: CHEBI:28802 ! flavonols
relationship: RO:0018034 CHEBI:60090 ! is protonated form of 7-hydroxyflavon-3-olate

[Term]
id: CHEBI:52289
name: wortmannin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:132992 ! has role radiosensitizing agent
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50914 ! has role EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
relationship: RO:0000087 CHEBI:76964 ! has role Penicillium metabolite
relationship: RO:0000087 CHEBI:88230 ! has role autophagy inhibitor

[Term]
id: CHEBI:52290
name: mitogen
def: "A chemical substance that encourages a cell to commence cell division, triggering mitosis." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:52342
name: ethyl formate
def: "A formate ester resulting from the formal condensation of formic acid with ethanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:52343 ! formate ester
relationship: RO:0000087 CHEBI:39276 ! has role fumigant
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:52343
name: formate ester
def: "An ester of formic acid." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:30751 ! has functional parent formic acid

[Term]
id: CHEBI:52357
name: chlorine dioxide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36871 ! inorganic radical
is_a: CHEBI:37750 ! chlorine oxide
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:132717 ! has role bleaching agent
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary

[Term]
id: CHEBI:52362
name: ortho-fused heteroarene
def: "An <em>ortho</em>-fused compound in which at least one of the rings contains at least one heteroatom." []
is_a: CHEBI:33637 ! ortho-fused compound
is_a: CHEBI:38180 ! polycyclic heteroarene

[Term]
id: CHEBI:52424
name: EC 3.2.1.* (glycosidase) inhibitor
def: "An EC 3.2.* (glycosylase) inhibitor that interferes with the action of any glycosidase (i.e. enzymes hydrolysing <em>O</em>- and <em>S</em>-glycosyl compounds, EC 3.2.1.*)." []
is_a: CHEBI:76761 ! EC 3.2.* (glycosylase) inhibitor

[Term]
id: CHEBI:52425
name: EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
def: "An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell." []
is_a: CHEBI:36044 ! antiviral drug
is_a: CHEBI:52424 ! EC 3.2.1.* (glycosidase) inhibitor

[Term]
id: CHEBI:52440
name: cephalosporin carboxylic acid anion
is_a: CHEBI:29067 ! carboxylic acid anion

[Term]
id: CHEBI:52464
name: jasmonate ester
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:36130 ! cyclic terpene ketone
relationship: RO:0018038 CHEBI:18292 ! has functional parent jasmonic acid

[Term]
id: CHEBI:52496
name: phenylcarbamic acid
is_a: CHEBI:33709 ! amino acid
relationship: RO:0018038 CHEBI:28616 ! has functional parent carbamic acid

[Term]
id: CHEBI:52497
name: maneb
def: "A polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. An agrochemical fungicide, it is used to control a variety of diseases including blight, leaf spot, rust, downy mildew and scab." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:35117 ! has part manganese coordination entity
relationship: BFO:0000051 CHEBI:83060 ! has part dithiocarbamate salt
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:52498
name: zineb
def: "A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33839 ! macromolecule
is_a: CHEBI:36566 ! zinc coordination entity
is_a: CHEBI:83060 ! dithiocarbamate salt
relationship: BFO:0000051 CHEBI:77308 ! has part ethylenebis(dithiocarbamate)
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:52507
name: haloindole
def: "A compound based on an indole skeleton, containing one or more halogen atoms" []
is_a: CHEBI:24828 ! indoles

[Term]
id: CHEBI:52535
name: dihydroporphyrin
def: "A porphyrin compound containing a porphyrin ring with one double bond fewer than in porphyrin itself." []
is_a: CHEBI:26214 ! porphyrins

[Term]
id: CHEBI:5254
name: galactolipid
def: "A glycolipid and which the glyco component is specified as galactosyl." []
is_a: CHEBI:33563 ! glycolipid

[Term]
id: CHEBI:52557
name: tetracyclic diterpenoid
def: "A diterpenoid with a tetracyclic skeleton." []
is_a: CHEBI:23849 ! diterpenoid

[Term]
id: CHEBI:52575
name: alkylglycerol
def: "A glycerol ether having at least one alkyl substituent on oxygen." []
is_a: CHEBI:24353 ! glycerol ether

[Term]
id: CHEBI:52625
name: inorganic hydroxy compound
is_a: CHEBI:24651 ! hydroxides
is_a: CHEBI:24835 ! inorganic molecular entity

[Term]
id: CHEBI:52629
name: EC 3.1.26.13 (retroviral ribonuclease H) inhibitor
def: "An inhibitor of ribonuclease H (EC 3.1.26.13), an enzyme required for specific hydrolysis of the RNA strand of an RNA/DNA hybrid." []
is_a: CHEBI:64947 ! anti-HIV-1 agent
is_a: CHEBI:76785 ! EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor

[Term]
id: CHEBI:52646
name: leptomycin B
def: "A leptomycin having a (2<i>E</i>,10<i>E</i>,12<i>E</i>,16<i>Z</i>,18<i>E</i>)-double bond configuration as well as an ethyl substituent at position 17." []
is_a: CHEBI:140345 ! hydroxy polyunsaturated fatty acid
is_a: CHEBI:52651 ! leptomycin
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:52651
name: leptomycin
def: "A complex, very long chain, polyunsaturated fatty acid whose core structure comprises 8-oxononadeca-2,10,12,16,18-pentaenoic acid having methyl substituents at positions 3, 5, 7, 9, 11 and 15 and a 3,6-dihydropyran-6-one-2-yl group at position 19." []
is_a: CHEBI:24654 ! hydroxy fatty acid
is_a: CHEBI:25000 ! lactone
is_a: CHEBI:26208 ! polyunsaturated fatty acid
is_a: CHEBI:27283 ! very long-chain fatty acid
is_a: CHEBI:35819 ! branched-chain fatty acid
is_a: CHEBI:59644 ! oxo fatty acid
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
relationship: RO:0018038 CHEBI:28866 ! has functional parent tetracosanoic acid

[Term]
id: CHEBI:52684
name: butanediol
def: "A member of the class of butanediols that is butane in which two of the hydrogens have been replaced by hydroxy groups." []
is_a: CHEBI:22944 ! butanediols
relationship: RO:0018040 CHEBI:37808 ! has parent hydride butane

[Term]
id: CHEBI:52717
name: bortezomib
def: "<small>L</small>-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at <em>N</em><small><sup>α</small></sup> by a pyrazin-2-ylcarbonyl group. It is a dipeptidyl boronic acid that reversibly inhibits the 26S proteasome." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22475 ! amino acid amide
is_a: CHEBI:38314 ! pyrazines
is_a: CHEBI:84144 ! L-phenylalanine derivative
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35820 ! has role antiprotozoal drug
relationship: RO:0000087 CHEBI:37670 ! has role protease inhibitor
relationship: RO:0000087 CHEBI:52726 ! has role proteasome inhibitor
relationship: RO:0018038 CHEBI:38267 ! has functional parent boronic acid

[Term]
id: CHEBI:52726
name: proteasome inhibitor
def: "A drug that blocks the action of proteasomes, cellular complexes that break down proteins." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:52837
name: quinolinium ion
is_a: CHEBI:25697 ! organic cation

[Term]
id: CHEBI:52845
name: cyclic organic group
def: "An organic group that consists of a closed ring. It may be a substituent or a skeleton." []
is_a: CHEBI:33247 ! organic group

[Term]
id: CHEBI:52855
name: inorganic nanoparticle
def: "A nanoparticle that contains no carbon." []
is_a: CHEBI:50803 ! nanoparticle

[Term]
id: CHEBI:52877
name: pinacyanol cation
def: "A cationic C3 cyanine dye having quinolin-2-yl units at each end." []
is_a: CHEBI:37960 ! cyanine dye
is_a: CHEBI:52837 ! quinolinium ion
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome

[Term]
id: CHEBI:528881
name: (9Z,12Z,15Z)-octadeca-9,12,15-trienoate
is_a: CHEBI:57560 ! long-chain fatty acid anion
relationship: RO:0018033 CHEBI:27432 ! is deprotonated form of alpha-linolenic acid

[Term]
id: CHEBI:52904
name: rose bengal(2-)
def: "The anionic form of a fluorescent dye derived from a polyhalogenated fluorescin." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
is_a: CHEBI:37929 ! xanthene dye
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0018033 CHEBI:87202 ! is deprotonated form of rose bengal free acid
relationship: RO:0018038 CHEBI:42492 ! has functional parent fluorescin

[Term]
id: CHEBI:5296
name: gemfibrozil
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35679 ! has role antilipemic drug
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:17418 ! has functional parent valeric acid

[Term]
id: CHEBI:52990
name: tin oxide
def: "A metal oxide containing tin and oxygen." []
is_a: CHEBI:133331 ! metal oxide
is_a: CHEBI:27008 ! tin molecular entity

[Term]
id: CHEBI:52991
name: tin dioxide
def: "A tin oxide compound consisting of tin(IV) covalently bound to two oxygen atoms." []
is_a: CHEBI:52990 ! tin oxide

[Term]
id: CHEBI:53000
name: epitope
def: "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:53030
name: oxysterol
def: "An oxygenated derivative of cholesterol" []
is_a: CHEBI:15889 ! sterol
relationship: RO:0018038 CHEBI:16113 ! has functional parent cholesterol

[Term]
id: CHEBI:53063
name: 2,4,6-trinitrobenzenesulfonic acid
def: "The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33555 ! arenesulfonic acid
is_a: CHEBI:35716 ! C-nitro compound
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:53000 ! has role epitope
relationship: RO:0000087 CHEBI:63490 ! has role explosive

[Term]
id: CHEBI:53091
name: carbodiimide
def: "Any organonitrogen compound that consists of two primary amino groups joined to a central carbon atom via N=C linkages." []
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:53095
name: imidazolines
def: "Diazoline compounds having the nitrogen atoms at the 1- and 3-positions and a double bond at an unspecified position." []
is_a: CHEBI:53123 ! diazoline

[Term]
id: CHEBI:5312
name: gentamicin sulfate
is_a: CHEBI:17833 ! gentamycin
is_a: CHEBI:38012 ! aminoglycoside sulfate salt
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent

[Term]
id: CHEBI:53121
name: adenosine A2A receptor antagonist
def: "An antagonist at the A<small><sub>2A</sub></small> receptor." []
is_a: CHEBI:71232 ! adenosine receptor antagonist

[Term]
id: CHEBI:53123
name: diazoline
def: "A five-membered organic heteromonocyclic compound containing two nitrogen atoms and a double bond." []
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:53156
name: polychlorobiphenyl
def: "A biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings." []
is_a: CHEBI:134045 ! polychlorinated dibenzodioxines and related compounds
is_a: CHEBI:35446 ! chlorobiphenyl
relationship: RO:0000087 CHEBI:138015 ! has role endocrine disruptor

[Term]
id: CHEBI:53181
name: pristane
def: "A norterpene that is an acyclic saturated hydrocarbon derived from phytane by loss of its C-16 terminal methyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:53182 ! norterpene
is_a: CHEBI:83563 ! long-chain alkane
relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant
relationship: RO:0000087 CHEBI:59163 ! has role biomarker

[Term]
id: CHEBI:53182
name: norterpene
def: "Any hydrocarbon formed by loss of a methyl group from a terpene." []
is_a: CHEBI:24632 ! hydrocarbon

[Term]
id: CHEBI:53183
name: apo carotenoid
def: "A compound arising from loss of part of the carotene skeleton (excluding retinoids)" []
is_a: CHEBI:24913 ! isoprenoid

[Term]
id: CHEBI:53212
name: isocyanates
def: "Organonitrogen compounds that are derivatives of isocyanic acid; compounds containing the isocyanate functional group ‒N=C=O (as opposed to the cyanate group, -O-C≡N)." []
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0018038 CHEBI:29202 ! has functional parent isocyanic acid

[Term]
id: CHEBI:53213
name: diisocyanate
def: "An isocyanate compound containing two isocyanate functional groups. Manufactured for reaction with polyols in the production of polyurethanes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:53212 ! isocyanates
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:53214
name: isophorone diisocyanate
def: "A diisocyanate in which the two isocyanate groups are linked by an isophorone substituent." []
is_a: CHEBI:53213 ! diisocyanate
relationship: RO:0018038 CHEBI:34800 ! has functional parent isophorone

[Term]
id: CHEBI:53216
name: dicyclohexylmethane-4,4'-diisocyanate
def: "A diisocyanate consisting of dicyclohexylmethane with two isocyanate groups at the 4- and 4'-positions." []
is_a: CHEBI:53213 ! diisocyanate

[Term]
id: CHEBI:53218
name: diphenylmethane-4,4'-diisocyanate
def: "A diisocyanate consisting of diphenylmethane with two isocyanate groups at the 4- and 4'-positions." []
is_a: CHEBI:53213 ! diisocyanate
relationship: RO:0000087 CHEBI:59174 ! has role hapten
relationship: RO:0018040 CHEBI:38884 ! has parent hydride diphenylmethane

[Term]
id: CHEBI:53225
name: poly(alkylene) macromolecule
def: "A macromolecule composed of repeating alkane or substituted alkane units." []
is_a: CHEBI:37997 ! homopolymer macromolecule

[Term]
id: CHEBI:53226
name: polyethylene macromolecule
def: "A macromolecule composed of ethane or substituted ethane units." []
is_a: CHEBI:53225 ! poly(alkylene) macromolecule

[Term]
id: CHEBI:53232
name: polyimide macromolecule
def: "A macromolecule composed of units connected by dicarboximide (-C(=O)-NR-C(=O)-) linkages, where R can be H or organyl." []
is_a: CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:53242
name: vinyl polymer macromolecule
def: "A macromolecule composed of repeating -CHR-CH2- units." []
is_a: CHEBI:53226 ! polyethylene macromolecule

[Term]
id: CHEBI:53259
name: poly(ethylene terephthalate) macromolecule
def: "A macromolecule composed of repeating ethylene terephthalate units." []
is_a: CHEBI:26178 ! polyester macromolecule

[Term]
id: CHEBI:53270
name: polystyrene macromolecule
def: "Macromolecules composed of repeating substituted or unsubstituted ethylbenzene units." []
is_a: CHEBI:53242 ! vinyl polymer macromolecule

[Term]
id: CHEBI:53276
name: poly(styrene)
def: "A polymer composed of repeating ethyl benzene groups." []
is_a: CHEBI:53270 ! polystyrene macromolecule

[Term]
id: CHEBI:53284
name: polyurethane macromolecule
def: "A homopolymer macromolecule composed of units connected by carbamate (-O-CO-NH-) linkages." []
is_a: CHEBI:37997 ! homopolymer macromolecule

[Term]
id: CHEBI:53291
name: 2-halophenol
def: "A halophenol in which the halogen atom is bonded to the carbon atom adjacent to the C‒OH group." []
is_a: CHEBI:38856 ! halophenol

[Term]
id: CHEBI:53309
name: polyanionic macromolecule
def: "A polymer carrying multiple negative charges." []
is_a: CHEBI:53368 ! ionic macromolecule

[Term]
id: CHEBI:53310
name: copolymer macromolecule
def: "A macromolecule derived from two or more species of monomer." []
is_a: CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:53339
name: olefinic fatty acid
def: "Any fatty acid containing at least one C=C double bond." []
is_a: CHEBI:27208 ! unsaturated fatty acid
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:53353
name: GHB receptor agonist
def: "A drug that binds to and activates γ-hydroxybutyric acid receptors." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:53368
name: ionic macromolecule
def: "A macromolecule containing ionic groups." []
is_a: CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:53404
name: poly(alkylene vinylene) macromolecule
def: "A macromolecule with the general formula (-CR<small><sub>2</sub></small>-CR=C(R)CR<small><sub>2</sub></small>-)n where R=H or an alkyl group." []
is_a: CHEBI:37997 ! homopolymer macromolecule

[Term]
id: CHEBI:53405
name: poly(isoprene) macromolecule
def: "A macromolecule composed of repeating 2-methylbut-2-ene units." []
is_a: CHEBI:53404 ! poly(alkylene vinylene) macromolecule

[Term]
id: CHEBI:53406
name: cis-1,4-polyisoprene
def: "A polymer composed of repeating <i>cis</i>-2-methylbut-2-ene units." []
is_a: CHEBI:53405 ! poly(isoprene) macromolecule

[Term]
id: CHEBI:53407
name: poly(lactic acid) macromolecule
def: "A macromolecule composed of repeating 2-hydroxypropanoyl units." []
is_a: CHEBI:26178 ! polyester macromolecule
is_a: CHEBI:37997 ! homopolymer macromolecule

[Term]
id: CHEBI:53443
name: salicylamides
is_a: CHEBI:22702 ! benzamides
relationship: RO:0018038 CHEBI:16914 ! has functional parent salicylic acid

[Term]
id: CHEBI:53448
name: methyl cellulose
def: "A (1→4)-β-<small>D</small>-glucan compound formed by methylating cellulose through exposure to NaOH/CH3Cl." []
is_a: CHEBI:28793 ! beta-D-glucan
relationship: RO:0018038 CHEBI:18246 ! has functional parent (1->4)-beta-D-glucan

[Term]
id: CHEBI:53468
name: salicylanilides
def: "The compound salicylanilide and its derivatives." []
is_a: CHEBI:13248 ! anilide
relationship: RO:0018038 CHEBI:32114 ! has functional parent salicylamide

[Term]
id: CHEBI:53503
name: cobalt chloride hexahydrate
def: "A hydrate of cobalt chloride containing cobalt (in +2 oxidation state), chloride and water moieties in the ratio 1:2:6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35505 ! hydrate
relationship: BFO:0000051 CHEBI:35696 ! has part cobalt dichloride
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:53505
name: 2-methoxypropane
def: "An ether compound having methyl and isopropyl as the two alkyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
relationship: RO:0000087 CHEBI:38867 ! has role anaesthetic

[Term]
id: CHEBI:53509
name: erlotinib hydrochloride
def: "The hydrochloride salt of erlotinib." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
is_a: CHEBI:73477 ! terminal acetylenic compound
relationship: BFO:0000051 CHEBI:114785 ! has part erlotinib
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37699 ! has role protein kinase inhibitor

[Term]
id: CHEBI:53521
name: random copolymer
def: "A copolymer consisting of macromolecules in which the probability of finding a given monomeric unit at any given site in the chain is independent of the nature of the adjacent units." []
is_a: CHEBI:53310 ! copolymer macromolecule

[Term]
id: CHEBI:53526
name: tritiated thymidine
def: "Thymidine linked to the radioisotope tritium. Used to label DNA in the study of cellular and viral DNA synthesis." []
is_a: CHEBI:139359 ! tritiated compound
is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside
relationship: RO:0018038 CHEBI:17748 ! has functional parent thymidine

[Term]
id: CHEBI:53555
name: toluene meta-diisocyanate
def: "A diisocyanate that consists of toluene bearing two isocyanato functional groups positioned <em>meta</em> to one another." []
is_a: CHEBI:53213 ! diisocyanate

[Term]
id: CHEBI:53556
name: toluene 2,4-diisocyanate
def: "A toluene <em>meta</em>-diisocyanate in which the isocyanato groups are at positions 2 and 4 relative to the methyl group on the benzene ring." []
is_a: CHEBI:53555 ! toluene meta-diisocyanate
relationship: RO:0000087 CHEBI:59174 ! has role hapten

[Term]
id: CHEBI:53557
name: toluene 2,6-diisocyanate
def: "A toluene <em>meta</em>-diisocyanate in which the isocyanato groups are at positions 2 and 6 relative to the methyl group on the benzene ring." []
is_a: CHEBI:53555 ! toluene meta-diisocyanate
relationship: RO:0000087 CHEBI:59174 ! has role hapten

[Term]
id: CHEBI:53559
name: topoisomerase IV inhibitor
def: "A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands." []
is_a: CHEBI:70727 ! topoisomerase inhibitor

[Term]
id: CHEBI:53578
name: hexamethylene diisocyanate
def: "A diisocyanate compound with the two isocyanates linked by a hexane-1,6-diyl group." []
is_a: CHEBI:53213 ! diisocyanate
relationship: RO:0000087 CHEBI:59174 ! has role hapten

[Term]
id: CHEBI:53620
name: methylisothiazolinone
def: "A 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom. It is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon<small><sup>TM</small></sup>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48902 ! 1,2-thiazoles
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:51076 ! has role antifouling biocide

[Term]
id: CHEBI:53621
name: chloromethylisothiazolinone
def: "A 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5. It is a powerful biocide and preservative and is the major active ingredient in the commercial product Kathon<small><sup>TM</small></sup>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:48902 ! 1,2-thiazoles
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:53620 ! has functional parent methylisothiazolinone

[Term]
id: CHEBI:53658
name: ceftriaxone(1-)
def: "A cephalosporin carboxylis acid anion having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups, formed by proton loss from the carboxy group of ceftriaxone." []
is_a: CHEBI:52440 ! cephalosporin carboxylic acid anion
relationship: RO:0018033 CHEBI:29007 ! is deprotonated form of ceftriaxone

[Term]
id: CHEBI:53661
name: alexidine
def: "An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge." []
is_a: CHEBI:53662 ! biguanides
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent

[Term]
id: CHEBI:53662
name: biguanides
def: "A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24436 ! guanidines
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent

[Term]
id: CHEBI:53665
name: oxazinoquinoline
def: "Any organic heterotricyclic compound based on a skeleton comprised of an oxazine ring fused onto a quinoline system." []
is_a: CHEBI:26979 ! organic heterotricyclic compound

[Term]
id: CHEBI:53669
name: cefadroxil(1-)
def: "A cephalosporin carboxylic acid anion having a 7β-[(2<i>R</i>)-2-amino-2-(4-hydroxyphenyl)acetyl]amino side-chain, formed by proton loss from the carboxy group of the cephalosporin cefadroxil." []
is_a: CHEBI:52440 ! cephalosporin carboxylic acid anion
relationship: RO:0018033 CHEBI:3479 ! is deprotonated form of cefadroxil

[Term]
id: CHEBI:53670
name: cefotaxime(1-)
def: "A cephalosporin carboxylic acid anion having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups, formed by proton loss from the carboxy group of the cephalosporin cefotaxime." []
is_a: CHEBI:52440 ! cephalosporin carboxylic acid anion
relationship: RO:0018033 CHEBI:204928 ! is deprotonated form of cefotaxime

[Term]
id: CHEBI:53676
name: ceftazidime(1-)
def: "A cephalosporin carboxylic acid anion formed by proton loss from the carboxy group of ceftazidime, a cephalosporin having 7β-[(2<i>Z</i>)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino and 3-pyridinium-1-ylmethyl side-groups." []
is_a: CHEBI:52440 ! cephalosporin carboxylic acid anion
relationship: RO:0018033 CHEBI:3508 ! is deprotonated form of ceftazidime

[Term]
id: CHEBI:53691
name: amidotrizoic acid
def: "A member of the class of benzoic acids that is benzoic acid having iodo substituents at the 2-, 4- and 6-positions and acetamido substituents at the 3- and 5-positions. It is used, mainly as its <em>N</em>-methylglucamine and sodium salts, as an X-ray contrast medium in gastrointestinal studies, angiography, and urography." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:48470 ! amidobenzoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37338 ! has role radioopaque medium
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:59731 ! is protonated form of amidotrizoic acid anion

[Term]
id: CHEBI:53720
name: poly(sulfide) macromolecule
def: "A macromolecule containing sulfur‒sulfur linkages in the backbone." []
is_a: CHEBI:33839 ! macromolecule

[Term]
id: CHEBI:53724
name: poly(chloroprene) macromolecule
def: "A macromolecule composed of repeating (2<i>Z</i>)-2-chlorobut-2-ene-1,4-diyl units." []
is_a: CHEBI:37997 ! homopolymer macromolecule

[Term]
id: CHEBI:53746
name: EC 1.1.1.205 (IMP dehydrogenase) inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:53756
name: HIV-1 reverse transcriptase inhibitor
def: "An entity which inhibits the activity of HIV-1 reverse transcriptase." []
is_a: CHEBI:52629 ! EC 3.1.26.13 (retroviral ribonuclease H) inhibitor

[Term]
id: CHEBI:53784
name: antispasmodic drug
def: "A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder." []
is_a: CHEBI:51371 ! muscle relaxant

[Term]
id: CHEBI:53802
name: dibenzooxazepine
def: "An organic heterotricyclic compound consisting of two benzene rings fused to a seven-membered ring containing one oxygen and one nitrogen atom." []
is_a: CHEBI:26979 ! organic heterotricyclic compound

[Term]
id: CHEBI:5384
name: glipizide
def: "An <em>N</em>-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:38314 ! pyrazines
is_a: CHEBI:62733 ! aromatic amide
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:77194 ! has role EC 2.7.1.33 (pantothenate kinase) inhibitor
relationship: RO:0000087 CHEBI:90415 ! has role insulin secretagogue

[Term]
id: CHEBI:5391
name: glucagon
def: "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." []
is_a: CHEBI:25905 ! peptide hormone
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:76916 ! has role hyperglycemic agent

[Term]
id: CHEBI:5417
name: glucosamine
is_a: CHEBI:24271 ! glucosamines

[Term]
id: CHEBI:5435
name: piperidine-2,6-dione
def: "A dicarboximide that is piperidine which is substituted by oxo groups at positions 2 and 6." []
is_a: CHEBI:35356 ! dicarboximide
is_a: CHEBI:48589 ! piperidones

[Term]
id: CHEBI:5441
name: glyburide
def: "An <em>N</em>-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:76983 ! N-sulfonylurea
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:131770 ! has role EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:77194 ! has role EC 2.7.1.33 (pantothenate kinase) inhibitor

[Term]
id: CHEBI:5445
name: glyceraldehyde
def: "An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33914 ! aldotriose
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite

[Term]
id: CHEBI:545959
name: homovanillic acid
def: "A monocarboxylic acid that is the 3-<em>O</em>-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite." []
is_a: CHEBI:134251 ! guaiacols
is_a: CHEBI:25384 ! monocarboxylic acid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:133744 ! is protonated form of homovanillate
relationship: RO:0018038 CHEBI:41941 ! has functional parent (3,4-dihydroxyphenyl)acetic acid

[Term]
id: CHEBI:55322
name: mu-opioid receptor agonist
def: "A compound that exhibits agonist activity at the μ-opioid receptor." []
is_a: CHEBI:60599 ! mu-opioid agent
is_a: CHEBI:60606 ! opioid receptor agonist

[Term]
id: CHEBI:55323
name: antidiarrhoeal drug
def: "Any drug found useful in the symptomatic treatment of diarrhoea." []
is_a: CHEBI:55324 ! gastrointestinal drug

[Term]
id: CHEBI:55324
name: gastrointestinal drug
def: "A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:55326
name: pentolinium tartrate
def: "The bitartrate salt of pentolinium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36963 ! organooxygen compound
is_a: CHEBI:50562 ! tartrate salt
relationship: BFO:0000051 CHEBI:347401 ! has part pentolinium ion
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0018038 CHEBI:35742 ! has functional parent tetracarboxylic acid

[Term]
id: CHEBI:55327
name: aci-nitroethane(1-)
def: "A nitrogen oxoanion arising from deprotonation of the hydroxy group of nitroethane." []
is_a: CHEBI:33458 ! nitrogen oxoanion
relationship: RO:0018033 CHEBI:77894 ! is deprotonated form of aci-nitroethane

[Term]
id: CHEBI:55339
name: camphorsulfonate salt
def: "Any salt of camphorsulfonic acid." []
is_a: CHEBI:55382 ! camphorsulfonates

[Term]
id: CHEBI:55347
name: vitamin K antagonist
def: "A class of anticoagulants which act by inhibiting the action of vitamin K." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:55352
name: (R)-atenolol
def: "The (<i>R</i>)-enantiomer of atenolol." []
is_a: CHEBI:2904 ! atenolol

[Term]
id: CHEBI:55366
name: ribonucleotide residue
def: "A nucleotide residue consisting of a nucleobase bound at the glycosidic nitrogen to a ribose ring that has a free valence at an oxygen atom and which is bound at the O-5' atom to a phosphate group, having a further free valence at one of its oxygen atoms." []
is_a: CHEBI:50319 ! nucleotide residue
relationship: RO:0018034 CHEBI:90675 ! is protonated form of ribonucleotide residue(1-)

[Term]
id: CHEBI:55369
name: ifosfamides
def: "Compounds containing an ifosfamide skeleton." []
is_a: CHEBI:35467 ! phosphorodiamide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37598 ! nitrogen mustard

[Term]
id: CHEBI:55370
name: imidazolidinone
def: "An imidazolidine containing one or more oxo groups." []
is_a: CHEBI:38261 ! imidazolidines

[Term]
id: CHEBI:55373
name: isoxazoles
def: "Oxazoles in which the N and O atoms are adjacent." []
is_a: CHEBI:35790 ! oxazole

[Term]
id: CHEBI:55374
name: oxazolidinone
def: "An oxazolidine containing one or more oxo groups." []
is_a: CHEBI:38329 ! oxazolidines

[Term]
id: CHEBI:55375
name: isoxazolidinone
def: "An oxazolidinone in which the N and O atoms are adjacent." []
is_a: CHEBI:55374 ! oxazolidinone

[Term]
id: CHEBI:55379
name: camphorsulfonic acid
def: "A sulfonic acid containing the camphorsulfonate anion." []
is_a: CHEBI:33551 ! organosulfonic acid
relationship: RO:0018034 CHEBI:55384 ! is protonated form of camphorsulfonate anion
relationship: RO:0018038 CHEBI:36773 ! has functional parent camphor

[Term]
id: CHEBI:55380
name: beta-hydroxy ketone
def: "A ketone containing a hydroxy group on the β-carbon relative to the C=O group." []
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:55381
name: diacetone alcohol
def: "A β-hydroxy ketone formed by hydroxylation of 4-methylpentan-2-one at the 4-position. It has been isolated from <em>Achnatherum robustum</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:55380 ! beta-hydroxy ketone
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:55382
name: camphorsulfonates
def: "Any salt or ester of camphorsulfonic acid." []
is_a: CHEBI:24532 ! organic heterocyclic compound
relationship: RO:0018038 CHEBI:55379 ! has functional parent camphorsulfonic acid

[Term]
id: CHEBI:55384
name: camphorsulfonate anion
def: "The conjugate base of camphorsulfonic acid." []
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:55379 ! is deprotonated form of camphorsulfonic acid

[Term]
id: CHEBI:55401
name: (R)-camphorsulfonic acid
def: "The <i>R</i> enantiomer of camphorsulfonic acid." []
is_a: CHEBI:55379 ! camphorsulfonic acid
relationship: RO:0018034 CHEBI:55407 ! is protonated form of (R)-camphorsulfonate
relationship: RO:0018039 CHEBI:55403 ! is enantiomer of (S)-camphorsulfonic acid

[Term]
id: CHEBI:55403
name: (S)-camphorsulfonic acid
def: "The <i>S</i> enantiomer of camphorsulfonic acid." []
is_a: CHEBI:55379 ! camphorsulfonic acid
relationship: RO:0018034 CHEBI:55408 ! is protonated form of (S)-camphorsulfonate
relationship: RO:0018039 CHEBI:55401 ! is enantiomer of (R)-camphorsulfonic acid

[Term]
id: CHEBI:55407
name: (R)-camphorsulfonate
def: "The <i>R</i> enantiomer of camphorsulfonate." []
is_a: CHEBI:55384 ! camphorsulfonate anion
relationship: RO:0018033 CHEBI:55401 ! is deprotonated form of (R)-camphorsulfonic acid
relationship: RO:0018039 CHEBI:55408 ! is enantiomer of (S)-camphorsulfonate

[Term]
id: CHEBI:55408
name: (S)-camphorsulfonate
def: "The <i>S</i> enantiomer of camphorsulfonate." []
is_a: CHEBI:55384 ! camphorsulfonate anion
relationship: RO:0018033 CHEBI:55403 ! is deprotonated form of (S)-camphorsulfonic acid
relationship: RO:0018039 CHEBI:55407 ! is enantiomer of (R)-camphorsulfonate

[Term]
id: CHEBI:55417
name: maleimides
def: "Compounds containing a cyclic dicarboximide skeleton in which the two carboacyl groups on nitrogen together with the nitrogen itself form a 1<em>H</em>-pyrrole-2,5-dione structure." []
is_a: CHEBI:35356 ! dicarboximide
relationship: RO:0018038 CHEBI:18300 ! has functional parent maleic acid

[Term]
id: CHEBI:55465
name: 7-hydroxyisoflavones
def: "A hydroxyisoflavone compound having a hydroxy group at the 7-position." []
is_a: CHEBI:38755 ! hydroxyisoflavone

[Term]
id: CHEBI:55505
name: 1,2-benzisothiazole
def: "A benzothiazole consisting of a benzene ring fused to an isothiazole." []
is_a: CHEBI:37947 ! benzothiazoles

[Term]
id: CHEBI:55517
name: trichothecene
def: "Any one of a large family of chemically related mycotoxins with a structure based on a sesquiterpene skeleton. The most important structural features causing the biological activities of trichothecenes are a 12,13-epoxy ring, the presence of hydroxy or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26658 ! sesquiterpenoid
is_a: CHEBI:32955 ! epoxide
is_a: CHEBI:38166 ! organic heteropolycyclic compound
relationship: RO:0000087 CHEBI:25442 ! has role mycotoxin

[Term]
id: CHEBI:5557
name: guanethidine
def: "A member of the class of  guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:38791 ! azocanes
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:37887 ! has role adrenergic antagonist
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:66991 ! has role sympatholytic agent
relationship: RO:0018038 CHEBI:42820 ! has functional parent guanidine
relationship: RO:0018040 CHEBI:38792 ! has parent hydride azocane

[Term]
id: CHEBI:5610
name: haloalkene
def: "A compound derived from an alkene by replacing a hydrogen atom with a halogen atom." []
is_a: CHEBI:24472 ! halohydrocarbon

[Term]
id: CHEBI:5613
name: haloperidol
def: "A compound composed of a central piperidine structure with hydroxy and <em>p</em>-chlorophenyl substituents at position 4 and an <em>N</em>-linked <em>p</em>-fluorobutyrophenone moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:48590 ! hydroxypiperidine
is_a: CHEBI:76224 ! aromatic ketone
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:65190 ! has role first generation antipsychotic
relationship: RO:0000087 CHEBI:66956 ! has role antidyskinesia agent

[Term]
id: CHEBI:5615
name: halothane
def: "A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24469 ! haloalkane
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37141 ! organobromine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic

[Term]
id: CHEBI:5631
name: heavy metal
def: "Any metal that is characterized by its rather high atomic mass and density. Although typically occurring in low concentrations, they can be found all throughout the Earth's crust (Commonly, a density of at least 5 g cm<small><sup>3</small></sup> is used to define a heavy metal and to differentiate it from other, ''light'' metals)." []
is_a: CHEBI:33521 ! metal atom

[Term]
id: CHEBI:5635
name: helenalin
def: "A sesquiterpene lactone that is 3,3a,4,4a,7a,8,9,9a-octahydroazuleno[6,5-<em>b</em>]furan-2,5-dione substituted by a hydroxy group at position 4, methyl groups at positions 4a and 8 and a methylidene group at position 3 (the 3a<i>S</i>,4<i>S</i>,4a<i>R</i>,7a<i>R</i>,8<i>R</i>,9a<i>R</i> stereoisomer)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:37581 ! gamma-lactone
is_a: CHEBI:37667 ! sesquiterpene lactone
is_a: CHEBI:3992 ! cyclic ketone
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:5653
name: hemiacetal
def: "A compound having the general formula RR'C(OH)OR'' (R'' ≠ H)." []
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:566274
name: malonaldehyde
def: "A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists <em>in vivo</em> mainly in the enol form." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38124 ! dialdehyde
relationship: RO:0000087 CHEBI:59163 ! has role biomarker

[Term]
id: CHEBI:566789
name: ethylaminium
def: "An ammonium ion resulting from the protonation of the nitrogen of ethylamine. The conjugate acid of ethylamine; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:15862 ! is protonated form of ethylamine

[Term]
id: CHEBI:5672
name: heptan-2-one
def: "A dialkyl ketone with methyl and pentyl as the alkyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18044 ! dialkyl ketone
is_a: CHEBI:51867 ! methyl ketone
relationship: RO:0000087 CHEBI:26013 ! has role pheromone
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite

[Term]
id: CHEBI:567361
name: cladribine
def: "2'-Deoxyadenosine in which the hydrogen at position 2 on the purine ring has been substituted by chlorine. It inhibits the synthesis and repair of DNA, particularly in  lymphocytes and monocytes, and is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including  hairy-cell leukaemia and chronic lymphocytic leukaemia." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19254 ! purine 2'-deoxyribonucleoside
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:5686
name: heterocyclic compound
def: "A cyclic compound having as ring members atoms of at least two different elements." []
is_a: CHEBI:33595 ! cyclic compound

[Term]
id: CHEBI:5691
name: Hexachloro-1,3-butadiene
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:5692
name: hexachlorobenzene
def: "A member of the class of chlorobenzenes that is benzene in which all of the hydrogens are replaced by chlorines. An agricultural fungicide introduced in the mid-1940s and formerly used as a seed treatment, its use has been banned since 1984 under the Stockholm Convention on Persistent Organic Pollutants." []
is_a: CHEBI:23132 ! chlorobenzenes
is_a: CHEBI:87034 ! aromatic fungicide
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:5693
name: hexachlorophene
def: "An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union." []
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:51614 ! diarylmethane
is_a: CHEBI:87039 ! bridged diphenyl fungicide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:569624
name: papulacandin B
def: "A papulacandin that is papulacandin A in which the (2<i>E</i>,4<i>E</i>)-deca-2,4-dienoyl chain at the <em>O</em>-(6') position is replaced by a (2<i>E</i>,4<i>Z</i>,6<i>E</i>)-8-hydroxydeca-2,4,6-trienoyl chain. It is the major carbohydrate-containing antibiotic from the deuteromycetous fungus <em>Papularia sphaerosperma</em> which shows potent antifungal activity against <em>Candida albicans</em>." []
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:63353 ! disaccharide derivative
is_a: CHEBI:72596 ! papulacandin
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0018038 CHEBI:36219 ! has functional parent alpha-lactose

[Term]
id: CHEBI:5705
name: Hexazinone
is_a: CHEBI:26588 ! 1,3,5-triazines

[Term]
id: CHEBI:57248
name: echinocandin
def: "Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-β-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most <em>Candida</em> spp and fungistatic against <em>Aspergillus</em> spp." []
is_a: CHEBI:46895 ! lipopeptide
is_a: CHEBI:86478 ! antibiotic antifungal agent
relationship: RO:0000087 CHEBI:230471 ! has role EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor

[Term]
id: CHEBI:57287
name: coenzyme A(4-)
def: "Tetraanion of coenzyme A." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15346 ! is deprotonated form of coenzyme A

[Term]
id: CHEBI:57295
name: (-)-ephedrinium
def: "Conjugate acid of (−)-ephedrine." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:15407 ! is protonated form of (-)-ephedrine
relationship: RO:0018039 CHEBI:149673 ! is enantiomer of (1S,2R)-ephedrine(1+)

[Term]
id: CHEBI:57299
name: ATP(3-)
def: "A ribonucleoside triphosphate oxoanion that is the trianion of adenosine 5'-triphosphate arising from deprotonation of three of the four free triphosphate OH groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:59724 ! ribonucleoside triphosphate oxoanion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:15422 ! is deprotonated form of ATP
relationship: RO:0018033 CHEBI:237958 ! is deprotonated form of ({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate
relationship: RO:0018034 CHEBI:30616 ! is protonated form of ATP(4-)

[Term]
id: CHEBI:57305
name: glycine zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of glycine." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:15428 ! is tautomer of glycine

[Term]
id: CHEBI:57406
name: prostaglandin D2(1-)
def: "A prostaglandin carboxylic acid anion that is the conjugate base of prostaglandin D<small><sub>2</sub></small>., obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:59326 ! prostaglandin carboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15555 ! is deprotonated form of prostaglandin D2

[Term]
id: CHEBI:57416
name: D-alanine zwitterion
def: "Zwitterionic form of <small>D</small>-alanine." []
is_a: CHEBI:66916 ! alanine zwitterion
relationship: RO:0018036 CHEBI:15570 ! is tautomer of D-alanine

[Term]
id: CHEBI:57427
name: L-leucine zwitterion
def: "Zwitterionic form of <small>L</small>-leucine." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:15603 ! is tautomer of L-leucine

[Term]
id: CHEBI:57433
name: sarcosine zwitterion
def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of sarcosine; major species at pH 7.3." []
is_a: CHEBI:66884 ! N-alkylglycine zwitterion
relationship: RO:0018036 CHEBI:15611 ! is tautomer of sarcosine

[Term]
id: CHEBI:57476
name: L-homoserine zwitterion
def: "Zwitterionic form of <small>L</small>-homoserine." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:15699 ! is tautomer of L-homoserine

[Term]
id: CHEBI:57491
name: staurosporinium
def: "Conjugate acid of staurosporine." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:15738 ! is protonated form of staurosporine

[Term]
id: CHEBI:57492
name: isopropylaminium
def: "Conjugate acid of isopropylamine." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:15739 ! is protonated form of isopropylamine

[Term]
id: CHEBI:57504
name: L-dopa zwitterion
def: "An amino acid zwitterion obtained from the transfer of a proton from the carboxy group to the amino group of <small>L</small>-dopa. Major microspecies at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:15765 ! is tautomer of L-dopa
relationship: RO:0018039 CHEBI:149689 ! is enantiomer of D-dopa zwitterion

[Term]
id: CHEBI:575568
name: atovaquone
def: "A naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132157 ! hydroxy-1,4-naphthoquinone
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:171664 ! has role antiamoebic agent
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:38503 ! has role EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor
relationship: RO:0000087 CHEBI:77103 ! has role EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor
relationship: RO:0000087 CHEBI:77106 ! has role EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor

[Term]
id: CHEBI:57560
name: long-chain fatty acid anion
def: "A fatty acid anion with a chain length of C<small><sub>13</sub></small> to C<small><sub>22</sub></small>." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:15904 ! is deprotonated form of long-chain fatty acid

[Term]
id: CHEBI:57586
name: biotinate
def: "Conjugate base of biotin arising from deprotonation of the carboxy group." []
is_a: CHEBI:176841 ! vitamin B7
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15956 ! is deprotonated form of biotin

[Term]
id: CHEBI:57592
name: cyclohexylsulfamate
def: "An organic sulfamate oxoanion that is the conjugate base of cyclohexylsulfamic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:61660 ! organic sulfamate oxoanion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:15964 ! is deprotonated form of cyclohexylsulfamic acid

[Term]
id: CHEBI:57603
name: ethanolaminium(1+)
def: "A primary aliphatic ammonium ion that is the conjugate acid of ethanolamine arising from protonation of the primary amino function." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58001 ! primary aliphatic ammonium ion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16000 ! is protonated form of ethanolamine

[Term]
id: CHEBI:57606
name: 5-oxoprolinate
def: "The conjugate base of 5-oxoproline." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16010 ! is deprotonated form of 5-oxoproline

[Term]
id: CHEBI:57630
name: gamma-amino-beta-hydroxybutyric acid zwitterion
def: "Zwitterionic form of γ-amino-β-hydroxybutyric acid having an anionic carboxy group and a protonated amino group." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018034 CHEBI:11955 ! is protonated form of 4-amino-3-hydroxybutanoate
relationship: RO:0018036 CHEBI:16080 ! is tautomer of gamma-amino-beta-hydroxybutyric acid

[Term]
id: CHEBI:57644
name: chlorogenate
def: "A monocarboxylic acid anion that is the conjugate base of chlorogenic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:16112 ! is deprotonated form of chlorogenic acid
relationship: RO:0018038 CHEBI:29751 ! has functional parent (-)-quinate

[Term]
id: CHEBI:57668
name: D-ornithinium(1+)
def: "The conjugate acid of <small>D</small>-ornithine having an anionic carboxy group and both amino groups protonated; major species at pH 7.3." []
is_a: CHEBI:35274 ! ammonium ion derivative
is_a: CHEBI:46912 ! ornithinium(1+)
relationship: RO:0018034 CHEBI:16176 ! is protonated form of D-ornithine

[Term]
id: CHEBI:57670
name: N-acylglycinate
def: "A carboxylic acid anion obtained by deprotonation of the carboxy group of any <em>N</em>-acylglycine." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:16180 ! is deprotonated form of N-acylglycine
relationship: RO:0018038 CHEBI:32508 ! has functional parent glycinate

[Term]
id: CHEBI:57694
name: quercetin-7-olate
def: "Conjugate base of quercetin arising from selective deprotonation of the 7-hydroxy group; major species at pH 7.3." []
is_a: CHEBI:58588 ! flavonol oxoanion
relationship: RO:0018033 CHEBI:16243 ! is deprotonated form of quercetin

[Term]
id: CHEBI:57703
name: 2-nitrophenolate
def: "The conjugate base of 2-nitrophenol; major apecies at pH 7.3." []
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0018033 CHEBI:16260 ! is deprotonated form of 2-nitrophenol

[Term]
id: CHEBI:57704
name: cationic chitosan
def: "Polycationic form of chitosan arising from global protonation of the 2-amino groups; major species at pH 7.3." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:16261 ! is protonated form of chitosan

[Term]
id: CHEBI:57726
name: D-proline zwitterion
def: "A <small>D</small>-α-amino acid zwitterion that is <small>D</small>-proline in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:16313 ! is tautomer of D-proline

[Term]
id: CHEBI:57738
name: 2-arylpropionate
def: "A class of carboxylic acid anions of general formula RCHCH3C(=O)O(−) where R represents an aryl group." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:16333 ! is deprotonated form of 2-arylpropionic acid
relationship: RO:0018038 CHEBI:17272 ! has functional parent propionate

[Term]
id: CHEBI:57742
name: guanidinoacetic acid zwitterion
def: "Zwitterionic form of guanidinoacetic acid having an anionic carboxy group and a protonated guanidino group; major species at pH 7.3." []
is_a: CHEBI:27369 ! zwitterion
relationship: RO:0018036 CHEBI:16344 ! is tautomer of guanidinoacetic acid

[Term]
id: CHEBI:57743
name: L-citrulline zwitterion
def: "Zwitterionic form of <small>L</small>-citrulline having an anionic carboxy group and a protonated amino group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0018036 CHEBI:16349 ! is tautomer of L-citrulline

[Term]
id: CHEBI:57746
name: 3',5'-cyclic GMP(1-)
def: "The conjugate base of guanosine 3',5'-cyclic phosphate arising from deprotonation of the free phosphate OH group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16356 ! is deprotonated form of 3',5'-cyclic GMP

[Term]
id: CHEBI:57756
name: sphingosine(1+)
def: "The cationic sphingoid resulting from the protonation of the amino group of sphingosine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:84410 ! sphingoid base(1+)
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16393 ! is protonated form of sphingosine
relationship: RO:0018039 CHEBI:77956 ! is enantiomer of L-erythro-sphingosine(1+)

[Term]
id: CHEBI:57757
name: D-threonine zwitterion
def: "A <small>D</small>-α-amino acid zwitterion that is <small>D</small>-threonine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:16398 ! is tautomer of D-threonine

[Term]
id: CHEBI:57762
name: L-valine zwitterion
def: "An <small>L</small>-α-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of <small>L</small>-valine; major species at pH 7.3." []
is_a: CHEBI:59869 ! L-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:16414 ! is tautomer of L-valine

[Term]
id: CHEBI:57770
name: trans-caffeate
def: "The conjugate base of <i>trans</i>-caffeic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16433 ! is deprotonated form of trans-caffeic acid

[Term]
id: CHEBI:5778
name: hydrochlorothiazide
def: "A benzothiadiazine that is 3,4-dihydro-2<em>H</em>-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:50265 ! benzothiadiazine
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35498 ! has role diuretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:57817
name: sphinganine(1+)
def: "A cationic sphingoid obtained by protonation of the amino group of sphinganine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:84410 ! sphingoid base(1+)
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16566 ! is protonated form of sphinganine

[Term]
id: CHEBI:57834
name: spermidine(3+)
def: "An ammonium ion that is the trication of spermidine, formed by protonation at all three nitrogens." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:16610 ! is protonated form of spermidine

[Term]
id: CHEBI:57865
name: uridine 5'-monophosphate(2-)
def: "A pyrimidine nucleoside 5'-monophosphate(2−) that results from the removal of two protons from the phosphate group of UMP." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138238 ! pyrimidine ribonucleoside 5'-monophosphate(2-)
is_a: CHEBI:26443 ! pyrimidine ribonucleoside monophosphate
is_a: CHEBI:26446 ! pyrimidine ribonucleotide
is_a: CHEBI:37010 ! ribonucleoside 5'-monophosphate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16695 ! is deprotonated form of uridine 5'-monophosphate

[Term]
id: CHEBI:57867
name: nucleoside 5'-phosphate dianion
def: "The conjugate base of a nucleoside 5'-phosphate." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:16701 ! is deprotonated form of nucleoside 5'-phosphate

[Term]
id: CHEBI:57869
name: 6-aminopenicillanic acid zwitterion
def: "Zwitterionic form of 6-aminopenicillanic acid arising from migration of a proton from the carboxy group to the 6-amino group; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018034 CHEBI:30938 ! is protonated form of 6-aminopenicillanate
relationship: RO:0018036 CHEBI:16705 ! is tautomer of 6-aminopenicillanic acid

[Term]
id: CHEBI:57871
name: codeine(1+)
def: "The conjugate acid of codeine arising from protonation of the tertiary amino group; major species at pH 7.3." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:16714 ! is protonated form of codeine

[Term]
id: CHEBI:57887
name: tryptaminium
def: "An  ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:65296 ! primary ammonium ion
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16765 ! is protonated form of tryptamine

[Term]
id: CHEBI:57917
name: 4-nitrophenolate
def: "A phenolate anion that is the conjugate base of 4-nitrophenol; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:16836 ! is deprotonated form of 4-nitrophenol

[Term]
id: CHEBI:57925
name: glutathionate(1-)
def: "A peptide anion obtained by deprotonation of both carboxy groups and protonation of the glutamyl amino group of glutathione; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60334 ! peptide anion
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16856 ! is deprotonated form of glutathione

[Term]
id: CHEBI:57926
name: L-threonine zwitterion
def: "Zwitterionic form of <small>L</small>-threonine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:16857 ! is tautomer of L-threonine

[Term]
id: CHEBI:57930
name: nucleoside 5'-diphosphate(3-)
def: "Trianion of nucleoside diphosphate arising from deprotonation of all three free OH groups of the diphosphate; major species at pH 7.3." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:16862 ! is deprotonated form of nucleoside 5'-diphosphate

[Term]
id: CHEBI:57954
name: 3-cyano-L-alaninate
def: "The conjugate base of 3-cyano-<small>L</small>-alanine; major species at pH 7.3." []
is_a: CHEBI:59814 ! L-alpha-amino acid anion
is_a: CHEBI:66934 ! cyanoamino acid anion
relationship: RO:0018033 CHEBI:16934 ! is deprotonated form of 3-cyano-L-alanine
relationship: RO:0018033 CHEBI:77860 ! is deprotonated form of 3-cyano-L-alanine zwitterion

[Term]
id: CHEBI:57966
name: beta-alanine zwitterion
def: "Zwitterionic form of β-alanine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:16958 ! is tautomer of beta-alanine

[Term]
id: CHEBI:57970
name: 1-acyl-sn-glycerol 3-phosphate(2-)
def: "Dianion of a 1-acyl-<em>sn</em>-glycerol 3-phosphate arising from deprotonation of both phosphate OH groups; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:77589 ! monoacyl-sn-glycerol 3-phosphate(2-)
is_a: CHEBI:78166 ! 2-lysophosphatidate(2-)
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16975 ! is deprotonated form of 1-acyl-sn-glycerol 3-phosphate

[Term]
id: CHEBI:57972
name: L-alanine zwitterion
def: "Zwitterionic form of <small>L</small>-alanine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." []
is_a: CHEBI:66916 ! alanine zwitterion
relationship: RO:0018036 CHEBI:16977 ! is tautomer of L-alanine

[Term]
id: CHEBI:57977
name: bilirubin(2-)
def: "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:28965 ! dicarboxylic acid dianion
is_a: CHEBI:59252 ! linear tetrapyrrole anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16990 ! is deprotonated form of bilirubin IXalpha

[Term]
id: CHEBI:57981
name: D-phenylalanine zwitterion
def: "A <small>D</small>-α-amino acid zwitterion that is <small>D</small>-phenylalanine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:16998 ! is tautomer of D-phenylalanine
relationship: RO:0018039 CHEBI:58095 ! is enantiomer of L-phenylalanine zwitterion

[Term]
id: CHEBI:57986
name: riboflavin(1-)
def: "An organic anion that is the conjugate base of riboflavin resulting from the removal of a proton from the nitrogen at position 3 (between the two carbonyl groups). Major microspecies at pH 7.3." []
is_a: CHEBI:176838 ! vitamin B2
is_a: CHEBI:60531 ! flavin(1-)
relationship: RO:0000087 CHEBI:23357 ! has role cofactor
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:17015 ! is deprotonated form of riboflavin

[Term]
id: CHEBI:58000
name: D-glutamine zwitterion
def: "Zwitterionic form of <small>D</small>-glutamine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:17061 ! is tautomer of D-glutamine

[Term]
id: CHEBI:58001
name: primary aliphatic ammonium ion
def: "The conjugate acid of a primary aliphatic amine." []
is_a: CHEBI:65296 ! primary ammonium ion
relationship: RO:0018034 CHEBI:17062 ! is protonated form of primary aliphatic amine

[Term]
id: CHEBI:58007
name: streptomycin(3+)
def: "Trication of streptomycin arising from protonation of the guanidino and secondary amino groups." []
is_a: CHEBI:60251 ! guanidinium ion
relationship: RO:0018034 CHEBI:17076 ! is protonated form of streptomycin

[Term]
id: CHEBI:5801
name: hydroxychloroquine
def: "An aminoquinoline that is chloroquine in which one of the <em>N</em>-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:36709 ! aminoquinoline
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0018033 CHEBI:149564 ! is deprotonated form of hydroxychloroquine(2+)
relationship: RO:0018038 CHEBI:3638 ! has functional parent chloroquine

[Term]
id: CHEBI:58029
name: cysteaminium
def: "An ammonium ion that is the conjugate acid of cysteamine; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17141 ! is protonated form of cysteamine

[Term]
id: CHEBI:58040
name: dimethylaminium
def: "An organic cation that is the conjugate acid of dimethylamine; major species at pH 7.3." []
is_a: CHEBI:58855 ! secondary aliphatic ammonium ion
relationship: RO:0018034 CHEBI:17170 ! is protonated form of dimethylamine

[Term]
id: CHEBI:58043
name: nucleoside 5'-monophosphate(2-)
def: "The dianion of a nucleoside monophosphate: major species at pH 7.3." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:17188 ! is deprotonated form of nucleoside 5'-monophosphate

[Term]
id: CHEBI:58046
name: 3,5-dibromo-4-oxidobenzonitrile(1-)
def: "The conjugate base of 3,5-dibromo-4-hydroxybenzonitrile; major species at pH 7.3." []
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0018033 CHEBI:17192 ! is deprotonated form of 3,5-dibromo-4-hydroxybenzonitrile

[Term]
id: CHEBI:58048
name: L-asparagine zwitterion
def: "Zwitterionic form of <small>L</small>-asparagine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:17196 ! is tautomer of L-asparagine

[Term]
id: CHEBI:58053
name: IMP(2-)
def: "A nucleoside 5'-monophosphate(2−) that results from the removal of two protons from the phosphate group of IMP; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58043 ! nucleoside 5'-monophosphate(2-)
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17202 ! is deprotonated form of IMP

[Term]
id: CHEBI:580604
name: (R)-ketamine
def: "The <i>R</i>- (less active) enantiomer of ketamine." []
is_a: CHEBI:6121 ! ketamine
relationship: RO:0018039 CHEBI:60799 ! is enantiomer of esketamine

[Term]
id: CHEBI:58070
name: dehydroascorbide(1-)
def: "Conjugate base of dehydroascorbic acid arising from removal of the acidic proton at the  C-2 position; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25696 ! organic anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17242 ! is deprotonated form of dehydroascorbic acid

[Term]
id: CHEBI:58072
name: carbon monoxide(1+)
def: "Conjugate acid of carbon monoxide arising from protonation of the carbon; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:17245 ! is protonated form of carbon monoxide

[Term]
id: CHEBI:58095
name: L-phenylalanine zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of <small>L</small>-phenylalanine; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:17295 ! is tautomer of L-phenylalanine
relationship: RO:0018039 CHEBI:57981 ! is enantiomer of D-phenylalanine zwitterion

[Term]
id: CHEBI:58097
name: morphine(1+)
def: "The conjugate acid of morphine arising from protonation of the tertiary amino group; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:17303 ! is protonated form of morphine

[Term]
id: CHEBI:58104
name: nucleoside 5'-triphoshate(3-)
def: "Trianion of nucleoside triphosphate arising from deprotonation of three of the four free triphosphate OH groups." []
is_a: CHEBI:59724 ! ribonucleoside triphosphate oxoanion
relationship: RO:0018033 CHEBI:17326 ! is deprotonated form of nucleoside 5'-triphoshate
relationship: RO:0018034 CHEBI:61557 ! is protonated form of nucleoside 5'-triphoshate(4-)

[Term]
id: CHEBI:58115
name: guanosine 5'-monophosphate(2-)
def: "A nucleoside 5'-monophosphate(2−) that results from the removal of two protons from the phosphate group of GMP." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58043 ! nucleoside 5'-monophosphate(2-)
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17345 ! is deprotonated form of guanosine 5'-monophosphate

[Term]
id: CHEBI:58123
name: (2S)-2-hydroxy monocarboxylic acid anion
def: "A hydroxy monocarboxylic acid anion where the hydroxy group is placed at position 2 (α to the carboxy group) and has (<i>S</i>)-stereochemistry; major species at pH 7.3." []
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0018033 CHEBI:17375 ! is deprotonated form of (2S)-2-hydroxy monocarboxylic acid
relationship: RO:0018039 CHEBI:58314 ! is enantiomer of (2R)-2-hydroxy monocarboxylic acid anion

[Term]
id: CHEBI:58145
name: agmatinium(2+)
def: "The dication resulting from deprotonation of the amino and guanidino groups of agmatine; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60251 ! guanidinium ion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:17431 ! is protonated form of agmatine

[Term]
id: CHEBI:58149
name: 3-hydroxyphenylacetate
def: "A hydroxy monocarboxylic acid anion that is the conjugate base of 3-hydroxyphenylacetic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:17445 ! is deprotonated form of 3-hydroxyphenylacetic acid

[Term]
id: CHEBI:58165
name: 3',5'-cyclic AMP(1-)
def: "An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17489 ! is deprotonated form of 3',5'-cyclic AMP

[Term]
id: CHEBI:58217
name: pentachlorophenolate
def: "A phenolate anion that is the conjugate base of pentachlorophenol; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018033 CHEBI:17642 ! is deprotonated form of pentachlorophenol

[Term]
id: CHEBI:58297
name: glutathione disulfide(2-)
def: "A doubly-charged peptide anion arising from deprotonation of the four carboxy groups and protonation of the two amino groups of glutathione disulfide; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60334 ! peptide anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17858 ! is deprotonated form of glutathione disulfide

[Term]
id: CHEBI:58314
name: (2R)-2-hydroxy monocarboxylic acid anion
def: "A hydroxy monocarboxylic acid anion where the hydroxy group is placed at position 2 (α to the carboxy group) and has (<i>R</i>)-stereochemistry; major species at pH 7.3." []
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0018033 CHEBI:17893 ! is deprotonated form of (2R)-2-hydroxy monocarboxylic acid
relationship: RO:0018039 CHEBI:58123 ! is enantiomer of (2S)-2-hydroxy monocarboxylic acid anion

[Term]
id: CHEBI:58315
name: L-tyrosine zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of <small>L</small>-tyrosine; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018033 CHEBI:32762 ! is deprotonated form of L-tyrosinium
relationship: RO:0018034 CHEBI:32760 ! is protonated form of L-tyrosinate(1-)
relationship: RO:0018036 CHEBI:17895 ! is tautomer of L-tyrosine

[Term]
id: CHEBI:5835
name: hypericin
is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0018040 CHEBI:49267 ! has parent hydride bisanthene

[Term]
id: CHEBI:58359
name: L-glutamine zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of <small>L</small>-glutamine; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:62031 ! polar amino acid zwitterion
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018036 CHEBI:18050 ! is tautomer of L-glutamine

[Term]
id: CHEBI:58360
name: 1-aminocyclopropanecarboxylic acid zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of 1-aminocyclopropanecarboxylic acid; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:30526 ! is protonated form of 1-aminocyclopropanecarboxylate
relationship: RO:0018036 CHEBI:18053 ! is tautomer of 1-aminocyclopropanecarboxylic acid

[Term]
id: CHEBI:58384
name: cadaverine(2+)
def: "An alkane-α,ω-diammonium(2+) ion that is the doubly-charged ammonium ion, arising from protonation of both nitrogens of cadaverine. The major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:70977 ! alkane-alpha,omega-diammonium(2+)
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:18127 ! is protonated form of cadaverine

[Term]
id: CHEBI:58389
name: trimethylammonium
def: "An ammonium ion that is the conjugate acid of trimethylamine, obtained via protonation of the nitrogen; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:18139 ! is protonated form of trimethylamine

[Term]
id: CHEBI:58395
name: myricetin(1-)
def: "A flavonol oxoanion that is the conjugate base of myricetin, arising from selective deprotonation of the 3-hydroxy group; major species at pH 7.3." []
is_a: CHEBI:58588 ! flavonol oxoanion
relationship: RO:0018033 CHEBI:18152 ! is deprotonated form of myricetin

[Term]
id: CHEBI:58429
name: alpha,alpha-trehalose 6-phosphate(2-)
def: "Dianion of α,α-trehalose 6-phosphate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:18283 ! is deprotonated form of alpha,alpha-trehalose 6-phosphate
relationship: RO:0018038 CHEBI:16551 ! has functional parent alpha,alpha-trehalose

[Term]
id: CHEBI:58431
name: jasmonate(1-)
def: "A 5-oxo monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of jasmonic acid. The major species at pH 7.3." []
is_a: CHEBI:136184 ! jasmonic acid anion
is_a: CHEBI:167055 ! Jasmonate derivatives
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:18292 ! is deprotonated form of jasmonic acid

[Term]
id: CHEBI:58432
name: histaminium
def: "An ammonium ion that is the conjugate acid of histamine protonated on the side-chain nitrogen." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:18295 ! is protonated form of histamine

[Term]
id: CHEBI:58448
name: L-thyroxine zwitterion
def: "Zwitterionic form of <small>L</small>-thyroxine." []
is_a: CHEBI:305790 ! thyroxine zwitterion
relationship: RO:0018036 CHEBI:18332 ! is tautomer of L-thyroxine

[Term]
id: CHEBI:58464
name: nucleoside 3',5'-cyclic phosphate anion
def: "The conjugate base of a nucleoside 3',5'-cyclic phosphate." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:18375 ! is deprotonated form of nucleoside 3',5'-cyclic phosphate

[Term]
id: CHEBI:58470
name: apigenin-7-olate
def: "The 7-oxoanion of apigenin." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:18388 ! is deprotonated form of apigenin

[Term]
id: CHEBI:58496
name: N-acetyl-D-amino acid anion
def: "The conjugate base of an <em>N</em>-acetyl-<small>D</small>-amino acid." []
is_a: CHEBI:59876 ! N-acyl-D-alpha-amino acid anion
relationship: RO:0018033 CHEBI:21501 ! is deprotonated form of N-acetyl-D-amino acid

[Term]
id: CHEBI:58535
name: N(8)-acetylspermidinium(2+)
def: "The dication of <em>N</em><small><sup>8</small></sup>-acetylspermidine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:27911 ! is protonated form of N(8)-acetylspermidine

[Term]
id: CHEBI:58549
name: kanamycin B(5+)
def: "An organic cation that is the pentacation of kanamycin B, obtained by protonation of the primary amino groups." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:28098 ! is protonated form of kanamycin B

[Term]
id: CHEBI:5855
name: ibuprofen
def: "A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:48578 ! has role radical scavenger
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50629 ! has role cyclooxygenase 2 inhibitor
relationship: RO:0000087 CHEBI:50630 ! has role cyclooxygenase 1 inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:132922 ! is protonated form of ibuprofen(1-)
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:58562
name: all-cis-5,8,11,14,17-icosapentaenoate
def: "An icosapentaenoate that is the conjugate base of <i>all</i>-<i>cis</i>-5,8,11,14,17-icosapentaenoic acid, arising from deprotonation of the carboxylic acid group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:61330 ! icosapentaenoate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28364 ! is deprotonated form of all-cis-5,8,11,14,17-icosapentaenoic acid

[Term]
id: CHEBI:58570
name: D-tyrosine zwitterion
def: "A <small>D</small>-α-amino acid zwitterion that is <small>D</small>-tyrosine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:28479 ! is tautomer of D-tyrosine

[Term]
id: CHEBI:58588
name: flavonol oxoanion
def: "The conjugate base of a flavonol compound." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:28802 ! is deprotonated form of flavonols

[Term]
id: CHEBI:5864
name: ifosfamide
def: "The simplest member of the class of  ifosfamides that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by 2-chloroethyl groups on both the nitrogen atoms respectively. It is a nitrogen mustard alkylating agent used in the treatment of advanced breast cancer." []
is_a: CHEBI:55369 ! ifosfamides
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:5870
name: imidacloprid
def: "An imidazolidine that is <em>N</em>-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38261 ! imidazolidines
is_a: CHEBI:39172 ! monochloropyridine
relationship: RO:0000087 CHEBI:25540 ! has role neonicotinoid insectide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:39174 ! has functional parent 2-chloropyridine

[Term]
id: CHEBI:58717
name: S-substituted L-cysteine zwitterion
def: "The zwitterionic form of an <em>S</em>-substituted <small>L</small>-cysteine." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:47910 ! is tautomer of S-substituted L-cysteine

[Term]
id: CHEBI:5882
name: imipramine hydrochloride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
relationship: BFO:0000051 CHEBI:47499 ! has part imipramine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant

[Term]
id: CHEBI:58855
name: secondary aliphatic ammonium ion
def: "A secondary aliphatic amine protonated on nitrogen." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:50981 ! is protonated form of secondary aliphatic amine

[Term]
id: CHEBI:58875
name: hyodeoxycholate
def: "A bile acid anion that is the conjugate base of hyodeoxycholic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36235 ! bile acid anion
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:52023 ! is deprotonated form of hyodeoxycholic acid

[Term]
id: CHEBI:5893
name: indapamide
def: "A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1<em>H</em>-indol-1-amine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24828 ! indoles
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35498 ! has role diuretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0018038 CHEBI:28179 ! has functional parent benzamide

[Term]
id: CHEBI:58942
name: cationic amino-acid residue
def: "An amino-acid residue protonated on nitrogen." []
is_a: CHEBI:64769 ! organic cationic group
relationship: RO:0018034 CHEBI:33708 ! is protonated form of amino-acid residue

[Term]
id: CHEBI:58945
name: organophosphate oxoanion
def: "An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated." []
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:26079 ! phosphoric acid derivative

[Term]
id: CHEBI:58950
name: very long-chain fatty acid anion
def: "Any fatty acid anion with a chain length greater than C<small><sub>22</sub></small>." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:27283 ! is deprotonated form of very long-chain fatty acid

[Term]
id: CHEBI:58951
name: short-chain fatty acid anion
def: "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C<small><sub>6</sub></small>)." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:26666 ! is deprotonated form of short-chain fatty acid

[Term]
id: CHEBI:58953
name: saturated fatty acid anion
def: "Any fatty acid anion in which there is no C‒C unsaturation." []
is_a: CHEBI:28868 ! fatty acid anion

[Term]
id: CHEBI:58954
name: straight-chain saturated fatty acid anion
def: "Any saturated fatty acid anion lacking a carbon side-chain." []
is_a: CHEBI:58953 ! saturated fatty acid anion
relationship: RO:0018033 CHEBI:39418 ! is deprotonated form of straight-chain saturated fatty acid

[Term]
id: CHEBI:58955
name: branched-chain fatty acid anion
def: "Any fatty acid anion with a carbon side-chain or isopropyl termination." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:35819 ! is deprotonated form of branched-chain fatty acid

[Term]
id: CHEBI:58956
name: branched-chain saturated fatty acid anion
def: "Any saturated fatty acid anion with a carbon side-chain or isopropyl termination." []
is_a: CHEBI:58953 ! saturated fatty acid anion
is_a: CHEBI:58955 ! branched-chain fatty acid anion
relationship: RO:0018033 CHEBI:39417 ! is deprotonated form of branched-chain saturated fatty acid

[Term]
id: CHEBI:58958
name: organosulfate oxoanion
def: "An organic anion of general formula RS(=O)2O(−) where R is an organyl group." []
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: RO:0018033 CHEBI:25704 ! is deprotonated form of organic sulfate
relationship: RO:0018038 CHEBI:16189 ! has functional parent sulfate

[Term]
id: CHEBI:589779
name: piperidinium
def: "The conjugate acid of piperidine; major species at pH 7.3." []
is_a: CHEBI:137419 ! secondary ammonium ion
relationship: RO:0018034 CHEBI:18049 ! is protonated form of piperidine

[Term]
id: CHEBI:58987
name: sildenafil citrate
def: "The citrate salt of sildenafil." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:50744 ! citrate salt
relationship: BFO:0000051 CHEBI:9139 ! has part sildenafil
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:71942 ! has role EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor

[Term]
id: CHEBI:59001
name: 4-vinylcyclohexene dioxide
def: "The diepoxide of 4-vinylcyclohexene." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32955 ! epoxide
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:59050
name: dimethyl sulfate
def: "The dimethyl ester of sulfuric acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29281 ! alkyl sulfate
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent

[Term]
id: CHEBI:59059
name: methyl isocyanate
def: "The isocyanate that is methane modified by a single isocyanato substituent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:53212 ! isocyanates
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:59062
name: polymyxin
def: "Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium <em>Bacillus polymyxa</em> and are selectively toxic for Gram-negative bacteria." []
is_a: CHEBI:24533 ! heterodetic cyclic peptide
is_a: CHEBI:46895 ! lipopeptide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent

[Term]
id: CHEBI:59064
name: colistin A
is_a: CHEBI:25903 ! peptide antibiotic
is_a: CHEBI:59062 ! polymyxin

[Term]
id: CHEBI:59105
name: EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor
def: "Any inhibitor of an acid—<small>D</small>-amino-acid ligase (EC 6.3.2.*)." []
is_a: CHEBI:75600 ! EC 6.3.* (C-N bond-forming ligase) inhibitor

[Term]
id: CHEBI:59107
name: EC 3.4.24.* (metalloendopeptidase) inhibitor
def: "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*)." []
is_a: CHEBI:37670 ! protease inhibitor

[Term]
id: CHEBI:59128
name: O-methylsalicylate
def: "Conjugate base of <em>O</em>-methylsalicylic acid." []
is_a: CHEBI:25236 ! methoxybenzoate
relationship: RO:0018033 CHEBI:421840 ! is deprotonated form of O-methylsalicylic acid

[Term]
id: CHEBI:59131
name: 5-chlorosalicylate
def: "Conjugate base of 5-chlorosalicylic acid." []
is_a: CHEBI:23133 ! chlorobenzoate
is_a: CHEBI:24675 ! hydroxybenzoate
relationship: RO:0018033 CHEBI:420128 ! is deprotonated form of 5-chlorosalicylic acid

[Term]
id: CHEBI:59132
name: antigen
def: "Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC)." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:59139
name: gibberellin carboxylic acid anion
def: "A carboxylic acid anion arising from deprotonation of one or more carboxy groups of any gibberellin." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:24250 ! is deprotonated form of gibberellin

[Term]
id: CHEBI:59163
name: biomarker
def: "A substance used as an indicator  of a biological state." []
is_a: CHEBI:47867 ! indicator

[Term]
id: CHEBI:59174
name: hapten
def: "Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:59202
name: straight-chain fatty acid
def: "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:59203 ! is protonated form of straight-chain fatty acid anion

[Term]
id: CHEBI:59203
name: straight-chain fatty acid anion
def: "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:59202 ! is deprotonated form of straight-chain fatty acid

[Term]
id: CHEBI:59219
name: ceruletide
def: "A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction." []
is_a: CHEBI:25676 ! oligopeptide
relationship: RO:0000087 CHEBI:33295 ! has role diagnostic agent
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug

[Term]
id: CHEBI:59230
name: acetate salt
def: "Any salt prepared using acetic acid as the acid component." []
is_a: CHEBI:24868 ! organic salt

[Term]
id: CHEBI:59238
name: cyclic fatty acid
def: "Any fatty acid containing anywhere in its structure a ring of atoms." []
is_a: CHEBI:35366 ! fatty acid

[Term]
id: CHEBI:5924
name: EC 3.4.21.* (serine endopeptidase) inhibitor
def: "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:59252
name: linear tetrapyrrole anion
def: "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." []
is_a: CHEBI:25696 ! organic anion

[Term]
id: CHEBI:59282
name: kappa-opioid receptor agonist
def: "A compound that exhibits agonist activity at the κ-opioid receptor." []
is_a: CHEBI:60603 ! kappa-opioid agent
is_a: CHEBI:60606 ! opioid receptor agonist

[Term]
id: CHEBI:59283
name: delta-opioid receptor antagonist
def: "Any compound that exhibits antagonist activity at the δ-opioid receptor." []
is_a: CHEBI:60601 ! delta-opioid agent
is_a: CHEBI:60605 ! opioid receptor antagonist

[Term]
id: CHEBI:59285
name: EC 1.14.13.132 (squalene monooxygenase) inhibitor
def: "An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132)." []
is_a: CHEBI:76841 ! EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor

[Term]
id: CHEBI:5931
name: insulin (human)
def: "An insulin that is produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two peptide chains, one containing 21 amino acid residues and the other containing 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into <em>E. coli</em>, which then produces insulin for human use. It is used in the treatment of type I and type II diabetes." []
is_a: CHEBI:145810 ! insulin
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent

[Term]
id: CHEBI:59326
name: prostaglandin carboxylic acid anion
def: "A prostanoid anion obtained by deprotonation of the carboxy group of any prostaglandin." []
is_a: CHEBI:62943 ! prostanoid anion
relationship: RO:0018033 CHEBI:26333 ! is deprotonated form of prostaglandin

[Term]
id: CHEBI:59331
name: mephedrone
def: "An aromatic ketone that is propiophenone substituted at C-4 and at C-β with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes." []
is_a: CHEBI:35338 ! amphetamines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:425902 ! has functional parent propiophenone

[Term]
id: CHEBI:59338
name: methylammonium
def: "The conjugate acid of methylamine; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:16830 ! is protonated form of methylamine

[Term]
id: CHEBI:5938
name: Interferon beta-1b
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:59414
name: muramyl dipeptide
def: "A glycopeptide that is <em>N</em>-propionyl-<small>L</small>-alanyl-<small>D</small>-α-glutamine in which the pro-<i>R</i> hydrogen of the propionyl group has been replaced by the oxygen at position 3 of 2-acetamido-2-deoxy-β-<small>D</small>-glucopyranose. A peptidoglycan constituent of both Gram-positive and Gram-negative bacteria." []
is_a: CHEBI:24396 ! glycopeptide
relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant
relationship: RO:0018034 CHEBI:194491 ! is protonated form of N-acetyl-beta-D-muramoyl-L-alanyl-D-isoglutamine(1-)

[Term]
id: CHEBI:59499
name: EC 3.4.13.* (dipeptidase) inhibitor
def: "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the action of a dipeptidase (EC 3.4.13.*)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:59512
name: cilastatin(1-)
def: "The anion resulting from the removal of a proton from a carboxylic acid group of cilastatin." []
is_a: CHEBI:35695 ! dicarboxylic acid monoanion
relationship: RO:0018033 CHEBI:3697 ! is deprotonated form of cilastatin

[Term]
id: CHEBI:59517
name: DNA synthesis inhibitor
def: "Any substance that inhibits the synthesis of DNA." []
is_a: CHEBI:76932 ! pathway inhibitor

[Term]
id: CHEBI:59527
name: naproxen(1-)
def: "The anion formed from naproxen by loss of a proton from the carboxy group." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:7476 ! is deprotonated form of naproxen

[Term]
id: CHEBI:59544
name: phosphoantigen
def: "Any antigen that is a phosphorylated microbial metabolite which activates an immune response in humans." []
is_a: CHEBI:59132 ! antigen

[Term]
id: CHEBI:59549
name: essential fatty acid
def: "Any member of the sub-set of polyunsaturated fatty acid for which there is an absolute dietary requirement." []
is_a: CHEBI:26208 ! polyunsaturated fatty acid

[Term]
id: CHEBI:59554
name: medium-chain fatty acid
def: "Any fatty acid with a chain length of between C<small><sub>6</sub></small> and C<small><sub>12</sub></small>." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:59558 ! is protonated form of medium-chain fatty acid anion

[Term]
id: CHEBI:59558
name: medium-chain fatty acid anion
def: "A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:59554 ! is deprotonated form of medium-chain fatty acid

[Term]
id: CHEBI:59561
name: diamino acid anion
def: "An  organic anion that is the conjugate base of diamino acid." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:35987 ! is deprotonated form of diamino acid

[Term]
id: CHEBI:5959
name: irbesartan
def: "A  biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension." []
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:35624 ! azaspiro compound
is_a: CHEBI:48420 ! biphenylyltetrazole
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:61016 ! has role angiotensin receptor antagonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:59607
name: quaternium-15
def: "A quaternary ammonium salt derived from hexamethylenetetramine; used as a preservative in many cosmetics and industrial substances. Also acts as a disinfectant and allergenic agent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35273 ! quaternary ammonium salt
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:59174 ! has role hapten
relationship: RO:0018038 CHEBI:6824 ! has functional parent hexamethylenetetramine

[Term]
id: CHEBI:5962
name: irgarol 1051
def: "A diamino-1,3,5-triazine that is  1,3,5-triazine-2,4-diamine carrying a <em>N</em>-<em>tert</em>-butyl, <em>N</em>'-cyclopropyl and a methylsulfanyl group at position 6." []
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:51454 ! cyclopropanes
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:51076 ! has role antifouling biocide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38071 ! has functional parent 1,3,5-triazine-2,4-diamine
relationship: RO:0018040 CHEBI:30259 ! has parent hydride 1,3,5-triazine

[Term]
id: CHEBI:59640
name: N-acetylglucosamine
def: "An <em>N</em>-acylglucosamine where the <em>N</em>-acyl group is specified as acetyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:21638 ! N-acylglucosamine
relationship: RO:0000087 CHEBI:78366 ! has role EC 2.7.1.1 (hexokinase) inhibitor

[Term]
id: CHEBI:59643
name: thia fatty acid
def: "Any fatty acid having at least one of the chain methylene groups replaced by sulfur. Members of this group are believed to have important pharmacological (antioxidant and antiatherosclerosis) properties." []
is_a: CHEBI:33576 ! sulfur-containing carboxylic acid
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:59848 ! is protonated form of thia fatty acid anion

[Term]
id: CHEBI:59644
name: oxo fatty acid
def: "Any fatty acid containing at least one aldehydic or ketonic group in addition to the carboxylic acid group." []
is_a: CHEBI:25754 ! oxo carboxylic acid
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:59836 ! is protonated form of oxo fatty acid anion

[Term]
id: CHEBI:59659
name: pyrenes
def: "Compounds containing a pyrene skeleton." []
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:59673
name: colistin B
is_a: CHEBI:25903 ! peptide antibiotic
is_a: CHEBI:59062 ! polymyxin

[Term]
id: CHEBI:59676
name: nystatins
def: "A class of polyene antifungal antibiotics produced by <em>Streptomyces noursei</em>, and other <em>Streptomyces</em> species." []
is_a: CHEBI:22507 ! aminoglycoside antibiotic
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:26191 ! polyol
is_a: CHEBI:36244 ! dicarboxylic acid monoester
is_a: CHEBI:48121 ! polyene
is_a: CHEBI:87113 ! antibiotic antifungal drug
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:59680
name: vasopressin receptor antagonist
def: "Any drug which blocks vasopressin receptors." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:59683
name: antipruritic drug
def: "A drug, usually applied topically, that relieves pruritus (itching)." []
is_a: CHEBI:50177 ! dermatologic drug

[Term]
id: CHEBI:59698
name: phosphoric acids
def: "Compounds containing one or more phosphoric acid units." []
is_a: CHEBI:33457 ! phosphorus oxoacid

[Term]
id: CHEBI:5971
name: irinotecan hydrochloride (anhydrous)
def: "A hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
relationship: BFO:0000051 CHEBI:90895 ! has part irinotecan(1+)
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50276 ! has role EC 5.99.1.2 (DNA topoisomerase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:59720
name: HPETE anion
def: "An anion arising from deprotonation of the carboxylic acid function of any mono-hydroperoxy (e)icosatetraenoic acid (HPETE)" []
is_a: CHEBI:134019 ! hydroperoxy polyunsaturated fatty acid anion
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:62937 ! icosanoid anion
relationship: RO:0018033 CHEBI:24644 ! is deprotonated form of HPETE

[Term]
id: CHEBI:59724
name: ribonucleoside triphosphate oxoanion
def: "An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate." []
is_a: CHEBI:58945 ! organophosphate oxoanion

[Term]
id: CHEBI:59731
name: amidotrizoic acid anion
def: "The anion obtained by removal of the proton from the carboxylic acid group of amidotrizoic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:48425 ! has role topical anaesthetic
relationship: RO:0018033 CHEBI:53691 ! is deprotonated form of amidotrizoic acid

[Term]
id: CHEBI:59739
name: electrophilic reagent
def: "A reagent that forms a bond to its reaction partner (the nucleophile) by accepting both bonding electrons from that reaction partner." []
is_a: CHEBI:33893 ! reagent
is_a: CHEBI:39143 ! Lewis acid

[Term]
id: CHEBI:59740
name: nucleophilic reagent
def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." []
is_a: CHEBI:33893 ! reagent
is_a: CHEBI:39144 ! Lewis base

[Term]
id: CHEBI:59745
name: chromatographic reagent
def: "A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase." []
is_a: CHEBI:33893 ! reagent

[Term]
id: CHEBI:59768
name: aliphatic aldehyde
def: "An aldehyde derived from an aliphatic compound" []
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:59769
name: acetal
def: "An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' ≠ H). Mixed acetals have R'' and R''' groups which differ." []
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:59770
name: cyclic acetal
def: "An acetal in the molecule of which the acetal carbon and one or both oxygen atoms thereon are members of a ring." []
is_a: CHEBI:24532 ! organic heterocyclic compound
is_a: CHEBI:59769 ! acetal

[Term]
id: CHEBI:59772
name: hemiketal
def: "A hemiacetal having the structure RR<small><sup>1</small></sup>C(OH)OR<small><sup>2</small></sup> (R, R<small><sup>1</small></sup>, R<small><sup>2</small></sup> ≠ H), derived from a ketone by formal addition of an alcohol to the carbonyl group." []
is_a: CHEBI:5653 ! hemiacetal

[Term]
id: CHEBI:59777
name: ketal
def: "An acetal of formula R<small><sub>2</sub></small>C(OR)<small><sub>2</sub></small> (R ≠ H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals." []
is_a: CHEBI:59769 ! acetal

[Term]
id: CHEBI:59779
name: cyclic ketal
def: "A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring." []
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:59777 ! ketal

[Term]
id: CHEBI:59780
name: cyclic hemiketal
def: "A hemiacetal  having the structure R<small><sub>2</sub></small>C(OH)OR (R ≠ H), derived from a ketone by formal addition of an alcohol to the carbonyl group. The term 'cyclic hemiketals', once abandoned by IUPAC, has been reinstated as a subclass of hemiacetals." []
is_a: CHEBI:38131 ! lactol
is_a: CHEBI:59772 ! hemiketal

[Term]
id: CHEBI:59792
name: thioacetal
def: "The sulfur analogue of 'acetal'.  The term includes monothioacetals having the structure R<small><sub>2</sub></small>C(OR')(SR') (subclass monothioketals, R ≠ H); and dithioacetals having the structure R<small><sub>2</sub></small>C(SR')<small><sub>2</sub></small> (subclass dithioketals, R ≠ H, R' ≠ H)." []
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:59793
name: monothioacetal
def: "A thioacetal having the structure R<small><sub>2</sub></small>C(OR')(SR'). The term includes monothioketals, R ≠ H, as a subclass." []
is_a: CHEBI:59792 ! thioacetal

[Term]
id: CHEBI:59794
name: dithioacetal
def: "A thioacetal having the structure R<small><sub>2</sub></small>C(SR')<small><sub>2</sub></small>. The term includes dithioketals (R ≠ H, R' ≠ H) as a subclass." []
is_a: CHEBI:59792 ! thioacetal

[Term]
id: CHEBI:59800
name: dithioketal
def: "A dithioacetal of formula R<small><sub>2</sub></small>C(SR')<small><sub>2</sub></small>, R ≠ H, R' ≠ H." []
is_a: CHEBI:59794 ! dithioacetal

[Term]
id: CHEBI:59806
name: (S)-nicotinium(1+)
def: "The conjugate acid of (<em>S</em>)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:17688 ! is protonated form of (S)-nicotine
relationship: RO:0018039 CHEBI:79008 ! is enantiomer of (R)-nicotinium(1+)

[Term]
id: CHEBI:59809
name: docetaxel trihydrate
def: "The trihydrate form of  docetaxel. It is used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:2468 ! secondary alpha-hydroxy ketone
is_a: CHEBI:35505 ! hydrate
relationship: BFO:0000051 CHEBI:4672 ! has part docetaxel anhydrous
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:59814
name: L-alpha-amino acid anion
def: "Conjugate base of an <small>L</small>-α-amino acid arising from deprotonation of the C-1 carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:15705 ! is deprotonated form of L-alpha-amino acid

[Term]
id: CHEBI:59826
name: progestin
def: "A synthetic progestogen." []
is_a: CHEBI:50745 ! progestogen

[Term]
id: CHEBI:59831
name: enyne
def: "An  acetylenic and an olefinic  compound containing a carbon chain that contains a carbon-carbon double bond and a carbon-carbon triple bond." []
is_a: CHEBI:73474 ! acetylenic compound
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:59835
name: hydroxy fatty acid anion
def: "The conjugate base of any hydroxy fatty acid, formed by deprotonation of the carboxylic acid moiety." []
is_a: CHEBI:28868 ! fatty acid anion
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0018033 CHEBI:24654 ! is deprotonated form of hydroxy fatty acid

[Term]
id: CHEBI:59836
name: oxo fatty acid anion
def: "A fatty acid anion carrying one or more oxo substituents" []
is_a: CHEBI:28868 ! fatty acid anion
is_a: CHEBI:35903 ! oxo carboxylic acid anion
relationship: RO:0018033 CHEBI:59644 ! is deprotonated form of oxo fatty acid

[Term]
id: CHEBI:59848
name: thia fatty acid anion
def: "The conjugate base of any thia fatty acid, formed by deprotonation of the carboxylic acid moiety." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:59643 ! is deprotonated form of thia fatty acid

[Term]
id: CHEBI:59851
name: benzyl halide
def: "Any compound containing a (halomethyl)benzene skeleton." []
is_a: CHEBI:17792 ! organohalogen compound

[Term]
id: CHEBI:59852
name: benzyl chlorides
def: "Any benzyl halide containing a (chloromethyl)benzene skeleton." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:59851 ! benzyl halide

[Term]
id: CHEBI:59864
name: depigmentation drug
def: "Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:59869
name: L-alpha-amino acid zwitterion
def: "Zwitterionic form of an <small>L</small>-α-amino acid having an anionic carboxy group and a protonated amino group." []
is_a: CHEBI:78608 ! alpha-amino-acid zwitterion
relationship: RO:0018036 CHEBI:15705 ! is tautomer of L-alpha-amino acid

[Term]
id: CHEBI:59871
name: D-alpha-amino acid zwitterion
def: "Zwitterionic form of a <small>D</small>-α-amino acid having an anionic carboxy group and a protonated amino group." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:16733 ! is tautomer of D-alpha-amino acid

[Term]
id: CHEBI:59874
name: N-acyl-L-alpha-amino acid anion
def: "A carboxylic acid anion that is the conjugate base of an <em>N</em>-acyl-<small>L</small>-α-amino acid arising from deprotonation of the C-1 carboxy group." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:48927 ! is deprotonated form of N-acyl-L-alpha-amino acid
relationship: RO:0018038 CHEBI:59814 ! has functional parent L-alpha-amino acid anion

[Term]
id: CHEBI:59876
name: N-acyl-D-alpha-amino acid anion
def: "The conjugate base of an <em>N</em>-acyl-<small>D</small>-α-amino acid arising from deprotonation of the C-1 carboxy group." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:15778 ! is deprotonated form of N-acyl-D-amino acid

[Term]
id: CHEBI:59888
name: gamma-aminobutyric acid zwitterion
def: "Zwitterionic form of γ-aminobutyric acid having an anionic carboxy group and a protonated amino group." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:16865 ! is tautomer of gamma-aminobutyric acid

[Term]
id: CHEBI:59897
name: EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
def: "A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce." []
is_a: CHEBI:22587 ! antiviral agent
is_a: CHEBI:38234 ! DNA polymerase inhibitor

[Term]
id: CHEBI:59900
name: caspofungin acetate
def: "The diacetate salt of caspofungin. It is used for the treatment of invasive candidiasis, and of aspergillosis in patients who are refractory to, or intolerant of, other therapy." []
is_a: CHEBI:59230 ! acetate salt
is_a: CHEBI:87113 ! antibiotic antifungal drug
relationship: BFO:0000051 CHEBI:474180 ! has part caspofungin

[Term]
id: CHEBI:59905
name: dopaminium(1+)
def: "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:18243 ! is protonated form of dopamine

[Term]
id: CHEBI:59997
name: EC 1.14.18.1 (tyrosinase) inhibitor
def: "Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC 1.14.18.1, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals." []
is_a: CHEBI:76845 ! EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor

[Term]
id: CHEBI:59999
name: chemical substance
def: "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." []
is_a: CHEBI:24431 ! chemical entity

[Term]
id: CHEBI:6000
name: Isocorydine
is_a: CHEBI:134209 ! aporphine alkaloid

[Term]
id: CHEBI:60004
name: mixture
def: "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." []
is_a: CHEBI:59999 ! chemical substance

[Term]
id: CHEBI:600103
name: daptomycin
def: "A polypeptide comprising <em>N</em>-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, <small>D</small>-alanine, aspartic acid, glycine, <small>D</small>-serine, <em>threo</em>-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine  with the alcohol group of the threonine residue." []
is_a: CHEBI:24533 ! heterodetic cyclic peptide
is_a: CHEBI:25061 ! lipopeptide antibiotic
is_a: CHEBI:25106 ! macrolide
relationship: RO:0000087 CHEBI:140190 ! has role calcium-dependent antibiotics
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:60027
name: polymer
def: "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." []
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:33839 ! has part macromolecule

[Term]
id: CHEBI:60029
name: homopolymer
def: "A homopolymer is a polymer composed of macromolecules, all of which are derived from one species of monomer." []
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:37997 ! has part homopolymer macromolecule

[Term]
id: CHEBI:60031
name: poly(alkylene) polymer
def: "A poly(alkylene) polymer is a homopolymer, composed of poly(alkylene) macromolecules." []
is_a: CHEBI:60029 ! homopolymer
relationship: BFO:0000051 CHEBI:53225 ! has part poly(alkylene) macromolecule

[Term]
id: CHEBI:60034
name: polyethylene polymer
def: "Polyethylene polymer is a poly(alkylene) polymer composed of polyethylene macromolecules." []
is_a: CHEBI:60031 ! poly(alkylene) polymer
relationship: BFO:0000051 CHEBI:53226 ! has part polyethylene macromolecule

[Term]
id: CHEBI:60038
name: flavonoid oxoanion
def: "Any anion arising from deprotonation of at least one OH group in a flavonoid compound." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:47916 ! is deprotonated form of flavonoid

[Term]
id: CHEBI:60039
name: L-proline zwitterion
def: "The zwitterion formed from <small>L</small>-proline by proton transfer from the carboxy group to the ring nitrogen. It is the predominant species at physiological pH." []
synonym: "L-proline" EXACT [UniProt]
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:17203 ! is tautomer of L-proline

[Term]
id: CHEBI:600520
name: micafungin
def: "A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-β-<small>D</small>-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy." []
is_a: CHEBI:57248 ! echinocandin
is_a: CHEBI:87113 ! antibiotic antifungal drug

[Term]
id: CHEBI:60056
name: cocaine(1+)
def: "The conjugate base of cocaine arising from protonation of the tertiary amino group; major species at pH 7.3." []
is_a: CHEBI:35274 ! ammonium ion derivative
is_a: CHEBI:37332 ! tropane alkaloid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:27958 ! is protonated form of cocaine

[Term]
id: CHEBI:60071
name: ertapenem(1-)
def: "The mono-anion resulting from the removal of a proton from one of the carboxyic acid groups of ertapenem." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:404903 ! is deprotonated form of ertapenem

[Term]
id: CHEBI:60082
name: vinca alkaloid cation
def: "Any cation arising from protonation of at least one of the amino functions in a vinca alkaloid." []
is_a: CHEBI:35274 ! ammonium ion derivative

[Term]
id: CHEBI:60090
name: 7-hydroxyflavon-3-olate
def: "Conjugate base of a 7-hydroxyflavonol compound arising from selective deprotonation of the 3-hydroxy group; major species at pH 7.3." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:52267 ! is deprotonated form of 7-hydroxyflavonol

[Term]
id: CHEBI:6015
name: isoflurane
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0018038 CHEBI:39832 ! has functional parent methoxyethane

[Term]
id: CHEBI:60151
name: oxidised LDL
def: "An oxidised form of low-density lipoprotein (LDL), regulated <em>in vivo</em> by a complex set of biochemical reactions and chiefly stimulated by the presence of necrotic cell debris and free radicals in the endothelium." []
is_a: CHEBI:39026 ! low-density lipoprotein

[Term]
id: CHEBI:60159
name: poly(lactic acid) polymer
def: "Poly(lactic acid) polymer is a homopolymer, composed of poly(lactic acid) macromolecules." []
is_a: CHEBI:60029 ! homopolymer
is_a: CHEBI:60160 ! polyester polymer
relationship: BFO:0000051 CHEBI:53407 ! has part poly(lactic acid) macromolecule

[Term]
id: CHEBI:60160
name: polyester polymer
def: "Polyester polymer is a polymer, composed of polyester macromolecules." []
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:26178 ! has part polyester macromolecule

[Term]
id: CHEBI:60164
name: ionic polymer
def: "An ionic polymer is a polymer, composed of ionic macromolecules." []
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:53368 ! has part ionic macromolecule

[Term]
id: CHEBI:60173
name: purine deoxyribonucleoside
def: "A deoxyribonucleoside containing a purine base." []
is_a: CHEBI:23636 ! deoxyribonucleoside
is_a: CHEBI:26394 ! purine nucleoside

[Term]
id: CHEBI:60186
name: EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
def: "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of <em>Ca</em><small><sup>2+</small></sup>-transporting ATPase (EC 3.6.3.8)." []
is_a: CHEBI:76895 ! EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor

[Term]
id: CHEBI:60194
name: peptide cation
def: "A cation formed by protonation of a peptide." []
is_a: CHEBI:25697 ! organic cation

[Term]
id: CHEBI:60240
name: divalent metal cation
def: "A metal cation with a valence of two." []
is_a: CHEBI:25213 ! metal cation
is_a: CHEBI:64641 ! divalent inorganic cation

[Term]
id: CHEBI:60242
name: monovalent inorganic cation
def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." []
is_a: CHEBI:36915 ! inorganic cation

[Term]
id: CHEBI:60247
name: silver ion
def: "A silver atom having a net electric charge." []
is_a: CHEBI:33966 ! elemental silver
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:60248
name: nickel ion
def: "A nickel atom having a net electric charge." []
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:60249
name: lead ion
def: "A lead atom having a net electric charge." []
is_a: CHEBI:36914 ! inorganic ion
is_a: CHEBI:37193 ! elemental lead

[Term]
id: CHEBI:60250
name: selenium ion
def: "A selenium atom having a net electric charge." []
is_a: CHEBI:36904 ! elemental selenium
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:60251
name: guanidinium ion
def: "R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives." []
is_a: CHEBI:35286 ! iminium ion

[Term]
id: CHEBI:60252
name: lead cation
def: "A lead atom having a positive net electric charge." []
is_a: CHEBI:25213 ! metal cation
is_a: CHEBI:60249 ! lead ion

[Term]
id: CHEBI:60253
name: silver cation
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:60247 ! silver ion

[Term]
id: CHEBI:60258
name: EC 3.4.* (hydrolases acting on peptide bond) inhibitor
def: "A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*)." []
is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor

[Term]
id: CHEBI:60270
name: caesium ion
def: "A caesium atom having a net electric charge." []
is_a: CHEBI:36914 ! inorganic ion
is_a: CHEBI:37128 ! caesium molecular entity

[Term]
id: CHEBI:60271
name: tellurium ion
def: "A tellurium atom having a net electric charge." []
is_a: CHEBI:36660 ! elemental tellurium
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:60272
name: aluminium ion
def: "An aluminium atom having a net electric charge." []
is_a: CHEBI:33628 ! elemental aluminium
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:6030
name: isoniazide
def: "A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine." []
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
is_a: CHEBI:35363 ! carbohydrazide
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:6032 ! has functional parent isonicotinic acid

[Term]
id: CHEBI:60302
name: L-thyroxine(1-)
def: "The α-amino-acid anion resulting from the removal of the proton from the carboxylic acid group of <small>L</small>-thyroxine." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:18332 ! is deprotonated form of L-thyroxine

[Term]
id: CHEBI:60311
name: thyroid hormone
def: "Any hormone produced by the thyroid gland" []
is_a: CHEBI:24621 ! hormone

[Term]
id: CHEBI:6032
name: isonicotinic acid
def: "A pyridinemonocarboxylic acid in which the carboxy group is at position 4 of the pyridine ring." []
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:38186 ! is protonated form of isonicotinate

[Term]
id: CHEBI:60330
name: 2-methyl-2-(methylsulfanyl)propanal oxime
def: "The oxime resulting from the formal condensation of 2-methyl-2-(methylsulfanyl)propanal with hydroxylamine. Addition of the oxime group to methyl isocyanate forms the final step in the synthesis of the systemic insecticide aldicarb." []
is_a: CHEBI:82744 ! aliphatic aldoxime
is_a: CHEBI:86315 ! methyl sulfide

[Term]
id: CHEBI:60334
name: peptide anion
def: "An anion formed by deprotonation of at least one peptide carboxy group." []
is_a: CHEBI:25696 ! organic anion

[Term]
id: CHEBI:60377
name: cytidine 5'-monophosphate(2-)
def: "A pyrimidine nucleoside 5'-monophosphate(2−) that results from the removal of two protons from the phosphate group of cytidine 5'-monophosphate; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:138238 ! pyrimidine ribonucleoside 5'-monophosphate(2-)
is_a: CHEBI:26443 ! pyrimidine ribonucleoside monophosphate
is_a: CHEBI:26446 ! pyrimidine ribonucleotide
is_a: CHEBI:37010 ! ribonucleoside 5'-monophosphate
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:17361 ! is deprotonated form of cytidine 5'-monophosphate

[Term]
id: CHEBI:60458
name: 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid
def: "Ethylbenzene in which the <em>pro</em>-<i>R</i> α-hydrogen is substituted by the nitrogen at the 1 position of 1<em>H</em>-imidazole-5-carboxylic acid. Its ethyl ester, etomidate, is used as an intravenous anaesthetic." []
is_a: CHEBI:38307 ! imidazolyl carboxylic acid

[Term]
id: CHEBI:60466
name: peptide zwitterion
def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." []
is_a: CHEBI:27369 ! zwitterion
relationship: RO:0018036 CHEBI:16670 ! is tautomer of peptide

[Term]
id: CHEBI:6047
name: isoprothiolane
def: "A malonate ester that is diisopropyl malonate in which the two methylene hydrogens at position 2 are replaced by a 1,3-dithiolan-2-ylidene group. An insecticide and fungicide used to control a range of diseases including <em>Pyricularia oryzae</em>, <em>Helminthosporium sigmoideum</em> and <em>Fusarium nivale</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35725 ! isopropyl ester
is_a: CHEBI:38083 ! malonate ester
is_a: CHEBI:39192 ! dithiolanes
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:83741 ! has role phospholipid biosynthesis inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018040 CHEBI:38079 ! has parent hydride 1,3-dithiolane

[Term]
id: CHEBI:60479
name: lysophosphatidylcholine
def: "An acylglycerophosphocholine resulting from partial hydrolysis of a phosphatidylcholine, which removes one of the fatty acyl groups. The structure is depicted in the image where R1 = acyl, R2 = H or where R1 = H, R2 = acyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36313 ! glycerophosphocholine
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:6049
name: isoproturon
def: "A member of the class of phenylureas that is 1,1-dimethylurea substituted by a <em>p</em>-cumenyl group at position 3. A selective, systemic herbicide used to control annual grasses and broadleaf weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:157693 ! 3-(3,4-substituted-phenyl)-1,1-dimethylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:60505
name: poly(chloroprene) polymer
def: "A homopolymer composed of poly(chloroprene) macromolecules." []
is_a: CHEBI:60029 ! homopolymer
relationship: BFO:0000051 CHEBI:53724 ! has part poly(chloroprene) macromolecule

[Term]
id: CHEBI:60521
name: indole alkaloid cation
def: "Any cation arising from protonation of at least one of the amino functions in an indole alkaloid." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative

[Term]
id: CHEBI:60531
name: flavin(1-)
def: "Flavin protonated to pH 7.3" []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:30527 ! is deprotonated form of flavin

[Term]
id: CHEBI:6054
name: Isosafrole
is_a: CHEBI:38298 ! benzodioxoles

[Term]
id: CHEBI:60575
name: phenoxy herbicide
def: "Any member of the class of herbicides whose members contain a phenoxy or substituted phenoxy group." []
is_a: CHEBI:24527 ! herbicide

[Term]
id: CHEBI:60598
name: opioid agent
def: "Any agent that acts on an opioid receptor or affects the life cycle of an opioid  transmitter." []
is_a: CHEBI:35942 ! neurotransmitter agent

[Term]
id: CHEBI:60599
name: mu-opioid agent
def: "Any agent that acts on a μ-opioid receptor." []
is_a: CHEBI:60598 ! opioid agent

[Term]
id: CHEBI:60600
name: amide fungicide
def: "Compounds that contain an amide group as a key feature of their structure and which have been used as fungicides." []
is_a: CHEBI:87012 ! amide antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:60601
name: delta-opioid agent
def: "Any agent that acts on a δ-opioid receptor." []
is_a: CHEBI:60598 ! opioid agent

[Term]
id: CHEBI:60603
name: kappa-opioid agent
def: "Any agent that acts on a κ-opioid receptor." []
is_a: CHEBI:60598 ! opioid agent

[Term]
id: CHEBI:60605
name: opioid receptor antagonist
def: "An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists." []
is_a: CHEBI:48706 ! antagonist
is_a: CHEBI:60598 ! opioid agent

[Term]
id: CHEBI:60606
name: opioid receptor agonist
def: "An agent that selectively binds to and activates an opioid receptor." []
is_a: CHEBI:48705 ! agonist
is_a: CHEBI:60598 ! opioid agent

[Term]
id: CHEBI:60607
name: metalaxyl-M
def: "A methyl <em>N</em>-(2,6-dimethylphenyl)-<em>N</em>-(methoxyacetyl)alaninate that is the more active <i>R</i>-enantiomer of metalaxyl. A systemic fungicide, it is active against phytopathogens of the order <em>Peronosporales</em> and is used to conrtrol <em>Pythium</em> in a number of vegetable crops." []
is_a: CHEBI:82790 ! methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate
is_a: CHEBI:83944 ! D-alanine derivative
is_a: CHEBI:87013 ! acylamino acid fungicide
is_a: CHEBI:87015 ! anilide fungicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0018039 CHEBI:82791 ! is enantiomer of (S)-metalaxyl

[Term]
id: CHEBI:60643
name: NMDA receptor antagonist
def: "Any substance that inhibits the action of <em>N</em>-methyl-<small>D</small>-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs." []
is_a: CHEBI:60798 ! excitatory amino acid antagonist

[Term]
id: CHEBI:60644
name: bridged diphenyl antifungal agent
def: "Any organic aromatic compound containing two phenyl (or substituted phenyl) groups attached to a single carbon or heteroatom and which has significant antifungal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33659 ! organic aromatic compound
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:60645
name: 2-hydroxy-3-methylbutyric acid
def: "A valine derivative that is valine in which the amino group has been replaced by a hydroxy group." []
is_a: CHEBI:49302 ! 2-hydroxy monocarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:64669 ! is protonated form of 2-hydroxy-3-methylbutyrate
relationship: RO:0018038 CHEBI:28484 ! has functional parent isovaleric acid

[Term]
id: CHEBI:60654
name: valproate
def: "A branched-chain saturated fatty acid anion that is the conjugate base of valproic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:58956 ! branched-chain saturated fatty acid anion
relationship: RO:0000087 CHEBI:35477 ! has role antimanic drug
relationship: RO:0018033 CHEBI:39867 ! is deprotonated form of valproic acid
relationship: RO:0018038 CHEBI:31011 ! has functional parent valerate

[Term]
id: CHEBI:6067
name: isotretinoin
def: "A retinoic acid that is <i>all</i>-<i>trans</i>-retinoic acid in which the double bond which is α,β- to the carboxy group is isomerised to <i>Z</i> configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases." []
is_a: CHEBI:26536 ! retinoic acid
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:50176 ! has role keratolytic drug
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0018034 CHEBI:169952 ! is protonated form of 13-cis-retinoate

[Term]
id: CHEBI:60720
name: sodium silicate
def: "An inorganic sodium salt having silicate as the counterion." []
is_a: CHEBI:38702 ! inorganic sodium salt
relationship: BFO:0000051 CHEBI:48123 ! has part silicate ion

[Term]
id: CHEBI:60737
name: polyurethane polymer
def: "A homopolymer, composed of polyurethane macromolecules." []
is_a: CHEBI:60029 ! homopolymer
relationship: BFO:0000051 CHEBI:53284 ! has part polyurethane macromolecule

[Term]
id: CHEBI:6076
name: itraconazole
def: "An <em>N</em>-arylpiperazine that is <i>cis</i>-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a <em>p</em>-[(±)1-<em>sec</em>-butyl-5-oxo-1,5-dihydro-4<em>H</em>-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:39430 ! dioxolane
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:59779 ! cyclic ketal
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87071 ! conazole antifungal drug
is_a: CHEBI:87101 ! triazole antifungal drug
relationship: RO:0000087 CHEBI:140921 ! has role Hedgehog signaling pathway inhibitor
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50183 ! has role P450 inhibitor
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:77748 ! has role EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor

[Term]
id: CHEBI:60761
name: floxuridine
def: "A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:60783 ! nucleoside analogue
relationship: RO:0000087 CHEBI:132992 ! has role radiosensitizing agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug

[Term]
id: CHEBI:6078
name: ivermectin
def: "A mixture consisting of ≥ 90% 22,23-dihydroavermectin B<small><sub>1a</sub></small> (R = Me) and ≤ 10% 22,23-dihydroavermectin B<small><sub>1b</sub></small> (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:63941 ! has part 22,23-dihydroavermectin B1a
relationship: BFO:0000051 CHEBI:63943 ! has part 22,23-dihydroavermectin B1b
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent
relationship: RO:0000087 CHEBI:73333 ! has role scabicide

[Term]
id: CHEBI:60783
name: nucleoside analogue
def: "An analogue of a nucleoside, being an <em>N</em>-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells." []
is_a: CHEBI:21731 ! N-glycosyl compound

[Term]
id: CHEBI:60798
name: excitatory amino acid antagonist
def: "Any substance which inhibits the action of receptors for excitatory amino acids." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:60799
name: esketamine
def: "The <i>S</i>- (more active) enantiomer of ketamine." []
is_a: CHEBI:6121 ! ketamine
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0018039 CHEBI:580604 ! is enantiomer of (R)-ketamine

[Term]
id: CHEBI:60804
name: copolymer
def: "A polymer, composed of copolymer macromolecules." []
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:53310 ! has part copolymer macromolecule

[Term]
id: CHEBI:60807
name: anaesthesia adjuvant
def: "Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time." []
is_a: CHEBI:60809 ! adjuvant

[Term]
id: CHEBI:60809
name: adjuvant
def: "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." []
is_a: CHEBI:52217 ! pharmaceutical

[Term]
id: CHEBI:60832
name: tubulin modulator
def: "Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules." []
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:60834
name: beta-carbolines
def: "Any pyridoindole containing a β-carboline skeleton and their hydrogenated derivatives" []
is_a: CHEBI:48888 ! pyridoindole

[Term]
id: CHEBI:60892
name: polyamino carboxylic acid
def: "An amino acid containing one or more nitrogen atoms connected through carbon atoms to one or more carboxy groups." []
is_a: CHEBI:33709 ! amino acid

[Term]
id: CHEBI:60895
name: D-alpha-amino acid anion
def: "Any α-amino acid anion in which the parent amino acid has <small>D</small>-configuration." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:16733 ! is deprotonated form of D-alpha-amino acid

[Term]
id: CHEBI:60911
name: racemate
def: "A racemate is an equimolar mixture of a pair of enantiomers." []
is_a: CHEBI:60004 ! mixture

[Term]
id: CHEBI:60915
name: diastereoisomeric mixture
def: "A mixture composed of two or more diastereoisomers (stereoisomers not related as mirror images)." []
is_a: CHEBI:60004 ! mixture

[Term]
id: CHEBI:60926
name: amino monosaccharide
def: "Any  amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group." []
is_a: CHEBI:28963 ! amino sugar

[Term]
id: CHEBI:60974
name: cyanoamino acid
def: "A non-proteinogenic amino acid modified by the addition of a cyano group." []
is_a: CHEBI:80291 ! aliphatic nitrile
is_a: CHEBI:83820 ! non-proteinogenic amino acid
relationship: RO:0018034 CHEBI:66934 ! is protonated form of cyanoamino acid anion

[Term]
id: CHEBI:60977
name: phenylalkylamine
def: "An arylalkylamine in which the aryl group is phenyl." []
is_a: CHEBI:22644 ! arylalkylamine

[Term]
id: CHEBI:60980
name: beta-glucoside
def: "A glucoside in which the anomeric carbon of the glycosidic bond is in a β configuration" []
is_a: CHEBI:24278 ! glucoside

[Term]
id: CHEBI:609827
name: L-canavanine
def: "A non-proteinogenic <small>L</small>-α-amino acid that is <small>L</small>-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. Although structurally related to <small>L</small>-arginine, it is non-proteinogenic." []
is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid
relationship: RO:0000087 CHEBI:22917 ! has role phytogenic insecticide
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:78902 ! is deprotonated form of L-canavanine(1+)
relationship: RO:0018036 CHEBI:405237 ! is tautomer of L-canavanine zwitterion
relationship: RO:0018038 CHEBI:15699 ! has functional parent L-homoserine

[Term]
id: CHEBI:61015
name: nephrotoxin
def: "A toxin that is produced by a biological organism such as a microbe, animal or plant which interferes with the function of the kidney in animals." []
is_a: CHEBI:27026 ! toxin
is_a: CHEBI:50909 ! nephrotoxic agent

[Term]
id: CHEBI:61016
name: angiotensin receptor antagonist
def: "A hormone antagonist that blocks angiotensin receptors." []
is_a: CHEBI:49020 ! hormone antagonist

[Term]
id: CHEBI:61049
name: tacrolimus (anhydrous)
def: "A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria <em>Streptomyces tsukubaensis</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:145565 ! macrolide lactam
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:61050
name: alkyl hydroperoxide
def: "A peroxol R‒OOH where the substituent R is an alkyl group." []
is_a: CHEBI:35924 ! peroxol

[Term]
id: CHEBI:61051
name: lipid hydroperoxide
def: "Any lipid carrying one or more hydroperoxy substituents." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:35924 ! peroxol

[Term]
id: CHEBI:61057
name: tacrolimus hydrate
def: "A hydrate that is the monohydrate form of tacrolimus." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35505 ! hydrate
relationship: BFO:0000051 CHEBI:61049 ! has part tacrolimus (anhydrous)
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent

[Term]
id: CHEBI:61073
name: oxygen radical
def: "An inorganic radical in which a free electron resides on one or more oxygen atoms of an oxygen species." []
is_a: CHEBI:26523 ! reactive oxygen species
is_a: CHEBI:36871 ! inorganic radical

[Term]
id: CHEBI:61115
name: EC 3.5.1.98 (histone deacetylase) inhibitor
def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." []
is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor

[Term]
id: CHEBI:61120
name: nucleobase-containing molecular entity
def: "Any compound that has a nucleobase as a part." []
is_a: CHEBI:33833 ! heteroarene
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: RO:0018038 CHEBI:18282 ! has functional parent nucleobase

[Term]
id: CHEBI:61153
name: clenbuterol(1+)
def: "The ammonium ion that is the conjugate acid of clenbuterol, formed by protonation of the secondary amine nitrogen atom." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:174690 ! is protonated form of clenbuterol

[Term]
id: CHEBI:61170
name: metoclopramide(1+)
def: "An ammonium ion obtained by protonation of the tertiary amino group of metoclopramide." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018033 CHEBI:61172 ! is deprotonated form of metoclopramide(2+)
relationship: RO:0018034 CHEBI:107736 ! is protonated form of metoclopramide

[Term]
id: CHEBI:61172
name: metoclopramide(2+)
def: "An ammonium ion that is obtained by protonation of both the tertiary amino group and the anilino nitrogen of metoclopramide." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:61170 ! is protonated form of metoclopramide(1+)

[Term]
id: CHEBI:6121
name: ketamine
def: "A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group." []
is_a: CHEBI:23482 ! cyclohexanones
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38877 ! has role intravenous anaesthetic
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:91519 ! has functional parent norketamine

[Term]
id: CHEBI:61249
name: hesperetin(1-)
def: "A flavonoid oxoanion that is the conjugate base of hesperetin arising from selective deprtotonation of the 7-hydroxy group." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:28230 ! is deprotonated form of hesperetin

[Term]
id: CHEBI:61266
name: hemicellulose
def: "Hemicelluloses are polysaccharides in plant cell walls that have β-(1→4)-linked backbones with an equatorial configuration. Hemicelluloses include xyloglucans, xylans, mannans and glucomannans, and β-(1→3,1→4)-glucans." []
is_a: CHEBI:18154 ! polysaccharide

[Term]
id: CHEBI:61269
name: scopolamine(1+)
def: "The ammonium ion resulting from the protonation of the amino group of scopolamine." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:16794 ! is protonated form of scopolamine

[Term]
id: CHEBI:6128
name: ketoprofen
def: "An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2." []
is_a: CHEBI:22726 ! benzophenones
is_a: CHEBI:35871 ! oxo monocarboxylic acid
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35544 ! has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:61292
name: guanyl nucleotide
def: "A nucleotide having guanine as the base." []
is_a: CHEBI:26395 ! purine nucleotide
relationship: RO:0018038 CHEBI:16235 ! has functional parent guanine

[Term]
id: CHEBI:61293
name: adenyl nucleotide
def: "A  nucleotide having adenine as the base." []
is_a: CHEBI:26395 ! purine nucleotide

[Term]
id: CHEBI:61295
name: guanyl ribonucleotide
def: "A purine ribonucleotide where the purine is guanine." []
is_a: CHEBI:26400 ! purine ribonucleotide
is_a: CHEBI:61292 ! guanyl nucleotide

[Term]
id: CHEBI:61296
name: adenyl ribonucleotide
def: "A purine riboncleotide where adenine is the purine." []
is_a: CHEBI:26400 ! purine ribonucleotide
is_a: CHEBI:61293 ! adenyl nucleotide

[Term]
id: CHEBI:61298
name: D-glucose- and/or D-galactose-substituted mannan
def: "A heteroglycan in which a backbone composed of <small>D</small>-mannose units is substituted with <small>D</small>-glucose and/or <small>D</small>-galactose units." []
is_a: CHEBI:16966 ! heteroglycan

[Term]
id: CHEBI:61310
name: chromium ion
def: "An chromium atom having a net electric charge." []
is_a: CHEBI:23237 ! chromium molecular entity
is_a: CHEBI:36914 ! inorganic ion

[Term]
id: CHEBI:61313
name: C21-steroid
def: "A steroid that has a structure based on a 21-carbon (pregnane) skeleton. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure." []
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:61330
name: icosapentaenoate
def: "A C<small><sub>20</sub></small>, straight-chain, polyunsaturated fatty acid anion containing five double bonds." []
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion

[Term]
id: CHEBI:61336
name: C4-dicarboxylate
def: "A dicarboxylate that contains four carbon atoms." []
is_a: CHEBI:28965 ! dicarboxylic acid dianion
relationship: RO:0018033 CHEBI:66873 ! is deprotonated form of C4-dicarboxylic acid

[Term]
id: CHEBI:61355
name: 3-hydroxy carboxylic acid
def: "Any hydroxy carboxylic acid which contains a hydroxy group located β- to the carboxylic acid group." []
is_a: CHEBI:24669 ! hydroxy carboxylic acid

[Term]
id: CHEBI:61379
name: harmala alkaloid
def: "Any member of a class of naturally occurring alkaloids based on a 1-methyl-9<em>H</em>-β-carboline skeleton." []
is_a: CHEBI:22315 ! alkaloid
is_a: CHEBI:60834 ! beta-carbolines

[Term]
id: CHEBI:61398
name: carbohydroximic acid
def: "A carboximidic acid having an OH or OR (R = organyl) group attached to the imide nitrogen." []
is_a: CHEBI:48378 ! carboximidic acid

[Term]
id: CHEBI:61409
name: dihydroxyphenylacetic acid
def: "A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents." []
is_a: CHEBI:25978 ! phenylacetic acids
is_a: CHEBI:35972 ! dihydroxy monocarboxylic acid

[Term]
id: CHEBI:61452
name: poly(ethylene terephthalate) polymer
def: "A polyester polymer, composed of poly(ethylene terephthalate) macromolecules." []
is_a: CHEBI:60160 ! polyester polymer
relationship: BFO:0000051 CHEBI:53259 ! has part poly(ethylene terephthalate) macromolecule
relationship: RO:0018034 CHEBI:131701 ! is protonated form of poly(ethylene terephthalate)(1-)

[Term]
id: CHEBI:61469
name: polyanionic polymer
def: "A polymer, composed of polyanion macromolecules." []
is_a: CHEBI:60164 ! ionic polymer
relationship: BFO:0000051 CHEBI:53309 ! has part polyanionic macromolecule

[Term]
id: CHEBI:61484
name: polyimide polymer
def: "A polymer, composed of polyimide macromolecules." []
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:53232 ! has part polyimide macromolecule

[Term]
id: CHEBI:61485
name: thiopental(1-)
def: "A thiolate anion resulting from the removal of a proton from one of the nitrogens of thiopental and tautomerisation." []
is_a: CHEBI:50539 ! thiolate anion
relationship: RO:0018033 CHEBI:102166 ! is deprotonated form of thiopental

[Term]
id: CHEBI:61557
name: nucleoside 5'-triphoshate(4-)
def: "A ribonucleoside triphosphate oxoanion arising from global deprotonation of the  triphosphate groups of any nucleoside triphosphate; major species at pH 7.3." []
is_a: CHEBI:59724 ! ribonucleoside triphosphate oxoanion
relationship: RO:0018033 CHEBI:58104 ! is deprotonated form of nucleoside 5'-triphoshate(3-)

[Term]
id: CHEBI:615597
name: benzyl chloride
def: "A member of the class of  benzyl chlorides that is toluene substituted on the α-carbon with chlorine." []
is_a: CHEBI:59852 ! benzyl chlorides

[Term]
id: CHEBI:61595
name: p-nitrophenyl group
def: "An aryl group obtained via removal of the hydrogen atom from the 4-position of nitrobenzene." []
is_a: CHEBI:33249 ! organyl group
relationship: RO:0018037 CHEBI:27798 ! is substitutent group from nitrobenzene

[Term]
id: CHEBI:616459
name: carbamimidoylazanium
is_a: CHEBI:35359 ! carboxamidine
relationship: RO:0018033 CHEBI:30087 ! is deprotonated form of guanidinium

[Term]
id: CHEBI:61655
name: steroid saponin
def: "Any saponin derived from a hydroxysteroid." []
is_a: CHEBI:26605 ! saponin
is_a: CHEBI:35341 ! steroid

[Term]
id: CHEBI:61660
name: organic sulfamate oxoanion
def: "An anion resulting from the removal of a proton from an organic sulfamic acid group." []
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:33482 ! sulfur oxoanion

[Term]
id: CHEBI:61666
name: amidobenzoate
def: "Any benzoate anion carrying one or more amido substituents." []
is_a: CHEBI:22718 ! benzoates
relationship: RO:0018033 CHEBI:48470 ! is deprotonated form of amidobenzoic acid

[Term]
id: CHEBI:61689
name: amino cyclitol
def: "Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups." []
is_a: CHEBI:23451 ! cyclitol

[Term]
id: CHEBI:61697
name: fatty acid derivative
def: "Any organic molecular entity derived from a fatty acid." []
is_a: CHEBI:18059 ! lipid
relationship: RO:0018038 CHEBI:35366 ! has functional parent fatty acid

[Term]
id: CHEBI:61777
name: terpene glycoside
def: "A terpenoid in which one or more hydroxy functions are glycosylated." []
is_a: CHEBI:24400 ! glycoside
is_a: CHEBI:26873 ! terpenoid

[Term]
id: CHEBI:61778
name: triterpenoid saponin
def: "A terpene glycoside in which the terpene moiety is a triterpenoid." []
is_a: CHEBI:26605 ! saponin
is_a: CHEBI:61777 ! terpene glycoside

[Term]
id: CHEBI:61870
name: monounsaturated fatty aldehyde
def: "Any fatty aldehyde with one double or triple bond located at any position in the aliphatic chain." []
is_a: CHEBI:231547 ! unsaturated fatty aldehyde

[Term]
id: CHEBI:61908
name: EC 1.14.13.39 (nitric oxide synthase) inhibitor
def: "An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39)." []
is_a: CHEBI:76841 ! EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor

[Term]
id: CHEBI:61950
name: microtubule-stabilising agent
def: "Any substance that interacts with tubulin to promote polymerisation of microtubules." []
is_a: CHEBI:60832 ! tubulin modulator

[Term]
id: CHEBI:61951
name: microtubule-destabilising agent
def: "Any substance that interacts with tubulin to inhibit polymerisation of microtubules." []
is_a: CHEBI:60832 ! tubulin modulator
is_a: CHEBI:64911 ! antimitotic

[Term]
id: CHEBI:61966
name: metabotropic glutamate receptor agonist
def: "An agonist that selectively binds to and activates a metabotropic glutamate receptor." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:62031
name: polar amino acid zwitterion
def: "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:26167 ! is tautomer of polar amino acid

[Term]
id: CHEBI:62049
name: acyl donor
def: "Any donor that can transfer acyl groups between molecular entities." []
is_a: CHEBI:17891 ! donor

[Term]
id: CHEBI:62064
name: butane-2,3-diol
def: "A butanediol in which hydroxylation is at C-2 and C-3." []
is_a: CHEBI:13643 ! glycol
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:52684 ! butanediol

[Term]
id: CHEBI:62071
name: 2-cis-abscisate
def: "A monocarboxylic acid anion that is the conjugate base of <i>cis</i>-abscisic acid; major species at pH 7.3." []
is_a: CHEBI:62432 ! abscisates
relationship: RO:0018033 CHEBI:22152 ! is deprotonated form of 2-cis-abscisic acid

[Term]
id: CHEBI:62081
name: 1,1-diunsubstituted alkanesulfonate
def: "An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134249 ! alkanesulfonate oxoanion
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic

[Term]
id: CHEBI:62086
name: metamizole(1-)
def: "An organosulfonate oxoanion resulting from the removal of a proton from the sulfonic acid group of metamizole." []
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:62088 ! is deprotonated form of metamizole

[Term]
id: CHEBI:62088
name: metamizole
def: "A pyrazole that is antiipyrine substituted at C-4 by a methyl(sulfomethyl)amino group, the sodium salt of which, metamizole sodium, was widely used as a powerful analgesic and antipyretic, but withdrawn from many markets from the 1970s due to a risk of causing risk of causing agranulocytosis." []
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:37793 ! amino sulfonic acid
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:49110 ! has role peripheral nervous system drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73263 ! has role cyclooxygenase 3 inhibitor
relationship: RO:0018034 CHEBI:62086 ! is protonated form of metamizole(1-)
relationship: RO:0018038 CHEBI:31225 ! has functional parent antipyrine

[Term]
id: CHEBI:62215
name: allelochemical
def: "A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory." []
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:62319
name: beta-Glcp-(1->6)-\{beta-Glcp-(1->6)-\{[beta-Glcp-(1->3)]5\}-[beta-Glcp-(1->3)]5\}-[beta-Glcp-(1->3)]4-beta-Glcp
def: "A β-<small>D</small>-glucan consisting of [3)-β-<small>D</small>-Glc<em>p</em>-(1→]<small><sub>15</sub></small> in which the fifth and tenth glucosides from the reducing end are substituted at position 6 by β-<small>D</small>-glucoside residues." []
is_a: CHEBI:28793 ! beta-D-glucan

[Term]
id: CHEBI:62431
name: abscisic acids
def: "Any apo carotenoid sesquiterpenoid that is 3-methylpenta-2,4-dienoic acid substituted at position 5 by a 1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl group and in which the acyclic double bond between positions 4 and 5 has <i>E</i>-configuration." []
is_a: CHEBI:134397 ! tertiary allylic alcohol
is_a: CHEBI:36758 ! apo carotenoid sesquiterpenoid
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
relationship: RO:0018034 CHEBI:62432 ! is protonated form of abscisates

[Term]
id: CHEBI:62432
name: abscisates
def: "A monocarboxylic acid anion obtained by removal of a proton from the carboxy group of any member of the class of abscisic acids." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:62431 ! is deprotonated form of abscisic acids

[Term]
id: CHEBI:62434
name: EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
def: "An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1)." []
is_a: CHEBI:38637 ! tyrosine kinase inhibitor
is_a: CHEBI:76817 ! EC 2.7.10.* (protein-tyrosine kinase) inhibitor

[Term]
id: CHEBI:62448
name: indole-3-carboxylate
def: "A monocarboxylic acid anion resulting from the deprotonation of the carboxyl group of indole-3-carboxylic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:24809 ! is deprotonated form of indole-3-carboxylic acid

[Term]
id: CHEBI:62488
name: signalling molecule
def: "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." []
is_a: CHEBI:33280 ! molecular messenger

[Term]
id: CHEBI:62499
name: methyl-branched fatty acid
def: "Any branched-chain fatty acid containing methyl branches only." []
is_a: CHEBI:35819 ! branched-chain fatty acid
relationship: RO:0018034 CHEBI:67013 ! is protonated form of methyl-branched fatty acid anion

[Term]
id: CHEBI:62501
name: folate(2-)
def: "The dicarboxylic acid dianion formed from folic acid by loss of a proton from each of the two carboxy groups in the glutamic acid moiety." []
is_a: CHEBI:28965 ! dicarboxylic acid dianion
is_a: CHEBI:67011 ! folates
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0018033 CHEBI:27470 ! is deprotonated form of folic acid

[Term]
id: CHEBI:62607
name: arsonium ion
def: "Arsonium, AsH<small><sub>4</sub></small><small><sup>+</small></sup>, and derivatives formed by substitution by univalent groups." []
is_a: CHEBI:22632 ! arsenic molecular entity
is_a: CHEBI:33702 ! polyatomic cation

[Term]
id: CHEBI:62608
name: EC 4.2.1.3 (aconitate hydratase) inhibitor
def: "An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the function of aconitase (EC 4.2.1.3)." []
is_a: CHEBI:76907 ! EC 4.2.1.* (hydro-lyases) inhibitor

[Term]
id: CHEBI:62643
name: anionic phospholipid
def: "Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1−), phosphatidate(2−), phosphatidylglycerol(1−)." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:16247 ! is deprotonated form of phospholipid

[Term]
id: CHEBI:62732
name: aromatic ester
def: "An ester where the ester linkage is bonded directly to an aromatic system." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:35701 ! ester

[Term]
id: CHEBI:62733
name: aromatic amide
def: "An amide in which the amide linkage is bonded directly to an aromatic system." []
is_a: CHEBI:32988 ! amide
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:62754
name: glycine receptor antagonist
def: "An antagonist that blocks glycine receptors." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:62761
name: tyrosine derivative
def: "An amino acid derivative resulting from reaction of tyrosine at the amino group or the carboxy group, any substitution of phenyl hydrogens, or from the replacement of any hydrogen of tyrosine by a heteroatom. The definition normally excludes peptides containing tyrosine residues." []
is_a: CHEBI:25985 ! phenylalanine derivative
relationship: RO:0018038 CHEBI:18186 ! has functional parent tyrosine

[Term]
id: CHEBI:62764
name: reactive nitrogen species
def: "A family of nitrogen molecular entities which are highly reactive and derived from nitric oxide (•NO) and superoxide (O<small><sub>2</sub></small>•<small><sup>−</small></sup>) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively." []
is_a: CHEBI:51143 ! nitrogen molecular entity

[Term]
id: CHEBI:62803
name: fuel additive
def: "Any additive that enhances the efficiency of fuel." []
is_a: CHEBI:747325 ! additive

[Term]
id: CHEBI:62805
name: isooctane
def: "An alkane that consists of pentane bearing two methyl substituents at position 2 and a single methyl substituent at position 4." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:18310 ! alkane
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent
relationship: RO:0000087 CHEBI:50909 ! has role nephrotoxic agent
relationship: RO:0000087 CHEBI:62803 ! has role fuel additive

[Term]
id: CHEBI:62837
name: 1-oleoyl-sn-glycerol 3-phosphate
def: "A 1-acyl-<em>sn</em>-glycerol 3-phosphate having oleoyl as the 1-<em>O</em>-acyl group." []
is_a: CHEBI:16975 ! 1-acyl-sn-glycerol 3-phosphate
relationship: RO:0018034 CHEBI:74544 ! is protonated form of 1-oleoyl-sn-glycero-3-phosphate(2-)

[Term]
id: CHEBI:62867
name: soyasaponin III
def: "A triterpenoid saponin that is composed of soyasapogenol B having a β-<small>D</small>-galactopyranosyl-(1→2)-β-<small>D</small>-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage." []
is_a: CHEBI:25872 ! pentacyclic triterpenoid
is_a: CHEBI:61778 ! triterpenoid saponin
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0018034 CHEBI:62911 ! is protonated form of soyasaponin III(1-)
relationship: RO:0018038 CHEBI:9209 ! has functional parent soyasapogenol B

[Term]
id: CHEBI:62868
name: hepatoprotective agent
def: "Any compound that is able to prevent damage to the liver." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:62871
name: EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor
def: "An EC 4.3.* (<em>C</em>‒<em>N</em> lyase) inhibitor that interferes with the action of phenylalanine ammonia-lyase (EC 4.3.1.24)." []
is_a: CHEBI:76832 ! EC 4.3.1.* (ammonia-lyase) inhibitor

[Term]
id: CHEBI:62872
name: EC 1.2.3.1 (aldehyde oxidase) inhibitor
def: "An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1)." []
is_a: CHEBI:76853 ! EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor

[Term]
id: CHEBI:62880
name: veliparib
def: "A benzimidazole substituted with a carbamoyl group at C-4 and a (2<i>R</i>)-2-methylpyrrolidin-2-yl moiety at C-2.  It is a potent, orally bioavailable PARP inhibitor." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22715 ! benzimidazoles
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:62913 ! has role EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor

[Term]
id: CHEBI:62889
name: organic diphosphate
def: "An organic phosphate ester formed by condensation of diphosphoric acid with one or more alcohols." []
is_a: CHEBI:25703 ! organic phosphate

[Term]
id: CHEBI:62911
name: soyasaponin III(1-)
def: "The monocarboxylic acid anion formed by removal of a proton from the carboxy group of soyasaponin III. It is the major microspecies present at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
is_a: CHEBI:63551 ! carbohydrate acid derivative anion
relationship: RO:0018033 CHEBI:62867 ! is deprotonated form of soyasaponin III

[Term]
id: CHEBI:62913
name: EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
def: "An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD<small><sup>+</small></sup> ADP-ribosyltransferase (EC 2.4.2.30)." []
is_a: CHEBI:76790 ! EC 2.4.2.* (pentosyltransferase) inhibitor

[Term]
id: CHEBI:62920
name: icosatetraenoate
def: "A polyunsaturated fatty acid anion that is the conjugate base of icosatetraenoic acid, obtained by deprotonation of the carboxy group. Major species at pH 7.3." []
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:36033 ! is deprotonated form of icosatetraenoic acid

[Term]
id: CHEBI:62932
name: mycophenolate
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of mycophenolic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:168396 ! is deprotonated form of mycophenolic acid

[Term]
id: CHEBI:62937
name: icosanoid anion
def: "The carboxylic acid anion that is the conjugate base of an icosanoid, formed when the carboxy group is deprotonated." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:23899 ! is deprotonated form of icosanoid

[Term]
id: CHEBI:62941
name: glycosylceramide
def: "A ceramide compound formed by the replacement of the glycosidic hydroxy group of a cyclic form of a monosaccharide (or derivative) by a ceramide group." []
is_a: CHEBI:17761 ! ceramide
is_a: CHEBI:24402 ! glycosphingolipid

[Term]
id: CHEBI:62943
name: prostanoid anion
def: "An icosanoid anion that is the conjugate base of a prostanoid." []
is_a: CHEBI:2580 ! unsaturated fatty acid anion
is_a: CHEBI:62937 ! icosanoid anion
relationship: RO:0018033 CHEBI:26347 ! is deprotonated form of prostanoid

[Term]
id: CHEBI:62968
name: crystalline cellulose
def: "A (1→4)-β-<small>D</small>-glucan (cellulose) in crystalline form with a structure consisting of several hundred to over ten thousand <small>D</small>-glucose residues joined by β(1→4) glycosidic linkages." []
is_a: CHEBI:18246 ! (1->4)-beta-D-glucan
is_a: CHEBI:72813 ! exopolysaccharide

[Term]
id: CHEBI:62980
name: homoserinate
def: "An α-amino-acid anion resulting from the removal of a proton from the carboxy group of homoserine." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:30653 ! is deprotonated form of homoserine

[Term]
id: CHEBI:62995
name: 2-methylpentane-2,4-diol
def: "A glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane)." []
is_a: CHEBI:13643 ! glycol

[Term]
id: CHEBI:63046
name: emulsifier
def: "The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:63047
name: food emulsifier
def: "A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food." []
is_a: CHEBI:63046 ! emulsifier
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:63048
name: 1,3-thiazolium cation
def: "An organic cation resulting from protonation or quaternisation at the 3-position of any 1,3-thiazole." []
is_a: CHEBI:25697 ! organic cation

[Term]
id: CHEBI:63054
name: osteogenesis regulator
def: "Any compound that induces or regulates osteogenesis." []
is_a: CHEBI:39317 ! growth regulator

[Term]
id: CHEBI:63056
name: zinc cation
def: "Any zinc ion that is positively charged." []
is_a: CHEBI:27365 ! zinc ion
is_a: CHEBI:33515 ! transition element cation

[Term]
id: CHEBI:63062
name: aluminium cation
def: "An aluminium atom having a positive net electric charge." []
is_a: CHEBI:25213 ! metal cation
is_a: CHEBI:60272 ! aluminium ion

[Term]
id: CHEBI:63063
name: cadmium cation
def: "A transition element cation where the metal is specifed as cadmium." []
is_a: CHEBI:33515 ! transition element cation

[Term]
id: CHEBI:63070
name: beta-alaninate
def: "A β-amino-acid anion that is the conjugate base of β-alanine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:49095 ! beta-amino-acid anion
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018033 CHEBI:16958 ! is deprotonated form of beta-alanine

[Term]
id: CHEBI:63090
name: EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor
def: "An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of purine nucleoside phosphorylase (EC 2.4.2.1)." []
is_a: CHEBI:76790 ! EC 2.4.2.* (pentosyltransferase) inhibitor

[Term]
id: CHEBI:63113
name: fingolimod(1+)
def: "An organic cation that is the conjugate acid of fingolimod." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:63115 ! is protonated form of fingolimod

[Term]
id: CHEBI:63114
name: sphingosine-1-phosphate receptor agonist
def: "An agonist that binds to and activates sphingosine 1-phosphate receptors." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:63115
name: fingolimod
def: "An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate." []
is_a: CHEBI:22501 ! aminodiol
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:63114 ! has role sphingosine-1-phosphate receptor agonist
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73416 ! has role CB1 receptor antagonist
relationship: RO:0018033 CHEBI:63113 ! is deprotonated form of fingolimod(1+)

[Term]
id: CHEBI:63131
name: EDTA(3-)
def: "A tetracarboxylic acid anion formed by deprotonation of three of the four carboxy groups in ethylenediaminetetraacetic acid (EDTA)." []
is_a: CHEBI:35754 ! tetracarboxylic acid anion
relationship: RO:0018033 CHEBI:64755 ! is deprotonated form of EDTA(2-)
relationship: RO:0018034 CHEBI:42191 ! is protonated form of EDTA(4-)

[Term]
id: CHEBI:63156
name: EC 1.1.3.13 (alcohol oxidase) inhibitor
def: "An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of alcohol oxidase (EC 1.1.3.13)." []
is_a: CHEBI:76836 ! EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor

[Term]
id: CHEBI:63157
name: EC 4.2.1.22 (cystathionine beta-synthase) inhibitor
def: "An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine β-synthase (EC 4.2.1.22)." []
is_a: CHEBI:76907 ! EC 4.2.1.* (hydro-lyases) inhibitor

[Term]
id: CHEBI:63158
name: EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor
def: "An  EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of mitochondrial carnitine <em>O</em>-palmitoyltransferase (EC 2.3.1.21)." []
is_a: CHEBI:76878 ! EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor

[Term]
id: CHEBI:63161
name: glycosyl compound
def: "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity." []
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:63165
name: ribonucleoside monophosphate oxoanion
def: "An organophosphate oxoanion resulting from deprotonation of at least one of the acidic hydroxy groups from the phosphate moiety of a ribonucleoside monophosphate." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:26558 ! is deprotonated form of ribonucleoside monophosphate

[Term]
id: CHEBI:63171
name: mononitrotoluene
def: "A nitrotoluene bearing a single nitro substituent at any position. A \"closed class\"." []
is_a: CHEBI:25566 ! nitrotoluene

[Term]
id: CHEBI:63173
name: T-cell proliferation inhibitor
def: "An inhibitor that interferes with the process of T-cell proliferation." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:63247
name: reducing agent
def: "The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:63248
name: oxidising agent
def: "A substance that removes electrons from another reactant in a redox reaction." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:63299
name: carbohydrate derivative
def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." []
is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives
relationship: RO:0018038 CHEBI:16646 ! has functional parent carbohydrate

[Term]
id: CHEBI:63317
name: barium chloride
def: "The inorganic dichloride salt of barium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36093 ! inorganic chloride
is_a: CHEBI:63320 ! barium salt
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:50509 ! has role potassium channel blocker

[Term]
id: CHEBI:63320
name: barium salt
def: "An alkaline earth salt that has barium(2+) as the cation." []
is_a: CHEBI:36364 ! alkaline earth salt
is_a: CHEBI:37133 ! barium molecular entity

[Term]
id: CHEBI:63332
name: EC 3.1.3.1 (alkaline phosphatase) inhibitor
def: "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1)." []
is_a: CHEBI:76775 ! EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor

[Term]
id: CHEBI:63353
name: disaccharide derivative
def: "A carbohydrate derivative that is formally obtained from a disaccharide." []
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: RO:0018038 CHEBI:36233 ! has functional parent disaccharide

[Term]
id: CHEBI:63367
name: monosaccharide derivative
def: "A carbohydrate derivative that is formally obtained from a monosaccharide." []
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: RO:0018038 CHEBI:35381 ! has functional parent monosaccharide

[Term]
id: CHEBI:63409
name: pentose derivative
def: "A monosaccharide derivative that is formally obtained from a pentose." []
is_a: CHEBI:63367 ! monosaccharide derivative
relationship: RO:0018038 CHEBI:25901 ! has functional parent pentose

[Term]
id: CHEBI:63423
name: alditol derivative
def: "A carbohydrate derivative that is formally obtained from an alditol." []
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: RO:0018038 CHEBI:17522 ! has functional parent alditol

[Term]
id: CHEBI:6343
name: labetalol
def: "A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((<i>R</i>,<i>S</i>)-labetolol, (<i>S</i>,<i>R</i>)-labetolol, (<i>S</i>,<i>S</i>)-labetalol and (<i>R</i>,<i>R</i>)-labetalol). It is an adrenergic antagonist used to treat high blood pressure." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:60915 ! diastereoisomeric mixture
relationship: BFO:0000051 CHEBI:167639 ! has part (S,S)-labetalol
relationship: BFO:0000051 CHEBI:167640 ! has part (R,S)-labetolol
relationship: BFO:0000051 CHEBI:167641 ! has part (S,R)-labetolol
relationship: BFO:0000051 CHEBI:94471 ! has part (R,R)-labetalol
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0000087 CHEBI:66991 ! has role sympatholytic agent

[Term]
id: CHEBI:63436
name: carbohydrate acid derivative
def: "A carbohydrate derivative that is formally obtained from a carbohydrate acid." []
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: RO:0018034 CHEBI:63551 ! is protonated form of carbohydrate acid derivative anion
relationship: RO:0018038 CHEBI:33720 ! has functional parent carbohydrate acid

[Term]
id: CHEBI:63457
name: fibroblast growth factor receptor antagonist
def: "An antagonist at the fibroblast growth factor receptor." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:63470
name: sulfur-containing amino-acid anion
def: "A sulfur-containing amino acid whose α-carboxylic acid group is ionized (not protonated)." []
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:26834 ! is deprotonated form of sulfur-containing amino acid

[Term]
id: CHEBI:63471
name: branched-chain amino-acid anion
def: "A branched-chain amino acid whose α-carboxylic acid group is ionized." []
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:22918 ! is deprotonated form of branched-chain amino acid

[Term]
id: CHEBI:63473
name: aromatic amino-acid anion
def: "An aromatic amino acid whose α-carboxylic acid group is ionized (non-protonated)." []
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:33856 ! is deprotonated form of aromatic amino acid

[Term]
id: CHEBI:63477
name: iodothyroninate
def: "An iodothyronine whose alpha carboxylic acid group of the tyrosine is ionized (not protonated)." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:24864 ! is deprotonated form of iodothyronine

[Term]
id: CHEBI:63490
name: explosive
def: "A substance capable of undergoing rapid and highly exothermic decomposition." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:63526
name: platinum cation
def: "A transition element cation that is a form of platinum having had electrons removed resulting in the 2+, 3+, or 4+ cation." []
is_a: CHEBI:33515 ! transition element cation
is_a: CHEBI:49202 ! elemental platinum

[Term]
id: CHEBI:63533
name: gonadotropin releasing hormone agonist
def: "Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response." []
is_a: CHEBI:51060 ! hormone agonist

[Term]
id: CHEBI:63534
name: monoamine
def: "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." []
is_a: CHEBI:64365 ! aralkylamino compound

[Term]
id: CHEBI:63551
name: carbohydrate acid derivative anion
def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:63436 ! is deprotonated form of carbohydrate acid derivative
relationship: RO:0018038 CHEBI:33721 ! has functional parent carbohydrate acid anion

[Term]
id: CHEBI:63578
name: iopromide
def: "A dicarboxylic acid diamide that consists of <em>N</em>-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A water soluble x-ray contrast agent for intravascular administration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35779 ! dicarboxylic acid diamide
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37338 ! has role radioopaque medium
relationship: RO:0000087 CHEBI:50909 ! has role nephrotoxic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:17754 ! has functional parent glycerol
relationship: RO:0018038 CHEBI:38801 ! has functional parent isophthalamide

[Term]
id: CHEBI:63580
name: ribavirin
def: "A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140324 ! primary carboxamide
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:61120 ! nucleobase-containing molecular entity
is_a: CHEBI:62733 ! aromatic amide
is_a: CHEBI:63594 ! 1-ribosyltriazole
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:59897 ! has role EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0018038 CHEBI:180482 ! has functional parent 1,2,4-triazole-3-carboxamide

[Term]
id: CHEBI:63581
name: stavudine
def: "A nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. An inhibitor of HIV-1 reverse transcriptase" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51659 ! dihydrofuran
is_a: CHEBI:60783 ! nucleoside analogue
is_a: CHEBI:61120 ! nucleobase-containing molecular entity
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:59897 ! has role EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0018038 CHEBI:17821 ! has functional parent thymine

[Term]
id: CHEBI:63593
name: 1-glycosyltriazole
def: "An <em>N</em>-glycosyl compound that consists of any triazole having a glycosyl residue attached at position 1." []
is_a: CHEBI:21731 ! N-glycosyl compound
is_a: CHEBI:35727 ! triazoles

[Term]
id: CHEBI:63594
name: 1-ribosyltriazole
def: "A 1-glycosyltriazole in which the glycosyl residue is specified as ribosyl." []
is_a: CHEBI:63593 ! 1-glycosyltriazole

[Term]
id: CHEBI:63598
name: levofloxacin
def: "An optically active form of ofloxacin having (<i>S</i>)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase." []
is_a: CHEBI:194135 ! 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:86324 ! quinolone antibiotic
is_a: CHEBI:87211 ! fluoroquinolone antibiotic
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:53559 ! has role topoisomerase IV inhibitor
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0018034 CHEBI:231553 ! is protonated form of levofloxacin(1-)
relationship: RO:0018039 CHEBI:46577 ! is enantiomer of dextrofloxacin

[Term]
id: CHEBI:63599
name: fludarabine phosphate
def: "A purine arabinonucleoside monophosphate having 2-fluoroadenine as the nucleobase. A prodrug, it is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. Once incorporated into DNA, 2-fluoro-ara-ATP functions as a DNA chain terminator. It is used for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to, or whose disease has progressed during, treatment with at least one standard alkylating-agent containing regimenas." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26397 ! purine ribonucleoside monophosphate
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:37514 ! purine arabinonucleoside monophosphate
is_a: CHEBI:60783 ! nucleoside analogue
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018038 CHEBI:72457 ! has functional parent 2-fluoroadenine

[Term]
id: CHEBI:63607
name: linezolid
def: "An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an <em>N</em>-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:55374 ! oxazolidinone
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor

[Term]
id: CHEBI:63613
name: nevirapine
def: "A dipyridodiazepine that is  5,11-dihydro-6<em>H</em>-dipyrido[3,2-<em>b</em>:2',3'-<em>e</em>][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:63667 ! dipyridodiazepine
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor

[Term]
id: CHEBI:63616
name: pemetrexed
def: "An <em>N</em>-acylglutamic acid in which the <em>N</em>-acyl group is specified as 4-[2-(2-amino-4-oxo-4,7-dihydro-1<em>H</em>-pyrrolo[2,3-<em>d</em>]pyrimidin-5-yl)ethyl]benzoyl. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT)." []
is_a: CHEBI:21650 ! N-acyl-L-glutamic acid
is_a: CHEBI:38670 ! pyrrolopyrimidine
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50683 ! has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor
relationship: RO:0000087 CHEBI:63720 ! has role EC 2.1.1.45 (thymidylate synthase) inhibitor
relationship: RO:0000087 CHEBI:63721 ! has role EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
relationship: RO:0018034 CHEBI:63724 ! is protonated form of pemetrexed(2-)

[Term]
id: CHEBI:63618
name: pravastatin
def: "A carboxylic ester resulting from the formal condensation of (<i>S</i>)-2-methylbutyric acid with the hydroxy group adjacent to the ring junction of (3<i>R</i>,5<i>R</i>)-7-[(1<i>S</i>,2<i>S</i>,6<i>S</i>,8<i>S</i>,8a<i>R</i>)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid. Derived from microbial transformation of mevastatin, pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). The sodium salt is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin." []
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:35744 ! carbocyclic fatty acid
is_a: CHEBI:35868 ! hydroxy monocarboxylic acid
is_a: CHEBI:36785 ! carbobicyclic compound
is_a: CHEBI:61355 ! 3-hydroxy carboxylic acid
is_a: CHEBI:87633 ! statin (semi-synthetic)
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:63660 ! is protonated form of pravastatin(1-)
relationship: RO:0018038 CHEBI:38655 ! has functional parent (S)-2-methylbutyric acid
relationship: RO:0018038 CHEBI:63655 ! has functional parent (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid

[Term]
id: CHEBI:63622
name: sotalol
def: "A sulfonamide that is <em>N</em>-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both β-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias." []
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:63647 ! is deprotonated form of sotalol(1+)

[Term]
id: CHEBI:63624
name: telbivudine
def: "A pyrimidine 2'-deoxyribonucleoside that is the <small>L</small>-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:59897 ! has role EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0018038 CHEBI:17821 ! has functional parent thymine
relationship: RO:0018039 CHEBI:17748 ! is enantiomer of thymidine

[Term]
id: CHEBI:63625
name: tenofovir (anhydrous)
def: "A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26069 ! phosphonic acids
is_a: CHEBI:26401 ! purines
is_a: CHEBI:60783 ! nucleoside analogue
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0018034 CHEBI:134504 ! is protonated form of tenofovir(1-)

[Term]
id: CHEBI:63632
name: topotecan
def: "A pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48626 ! pyranoindolizinoquinoline
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50276 ! has role EC 5.99.1.2 (DNA topoisomerase) inhibitor

[Term]
id: CHEBI:63633
name: triptorelin
def: "An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, <small>D</small>-tryptophyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It is an agonist analogue of gonadotropin-releasing hormone." []
is_a: CHEBI:15841 ! polypeptide
is_a: CHEBI:25676 ! oligopeptide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:49323 ! has role contraceptive drug
relationship: RO:0000087 CHEBI:63533 ! has role gonadotropin releasing hormone agonist
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:63637
name: vemurafenib
def: "A pyrrolopyridine that is 1<em>H</em>-pyrrolo[2,3-<em>b</em>]pyridine which is substituted at position 5 by a <em>p</em>-chlorophenyl group and at positions 3 by a 3-amino-2,6-difluorobenzoyl group, the amino group of which has undergone formal condensation with propane-1-sulfonic acid to give the corresponding sulfonamide. An inhibitor of BRAF and other kinases." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:38582 ! difluorobenzene
is_a: CHEBI:46771 ! pyrrolopyridine
is_a: CHEBI:76224 ! aromatic ketone
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75047 ! has role B-Raf inhibitor

[Term]
id: CHEBI:63647
name: sotalol(1+)
def: "An ammonium ion resulting from the protonation of the nitrogen of the secondary amino group of sotalol." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:63622 ! is protonated form of sotalol

[Term]
id: CHEBI:63655
name: (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
def: "A 3-hydroxy carboxylic acid that is (3<i>R</i>,5<i>R</i>)-3,5-dihydroxyheptanoic acid in which one of the methyl hydrogens is substituted by a (1<i>S</i>,2<i>S</i>,6<i>S</i>,8<i>S</i>,8a<i>R</i>)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl group." []
is_a: CHEBI:134396 ! secondary allylic alcohol
is_a: CHEBI:142348 ! hexahydronaphthalenes
is_a: CHEBI:61355 ! 3-hydroxy carboxylic acid

[Term]
id: CHEBI:63660
name: pravastatin(1-)
def: "A monocarboxylic acid anion resulting from the deprotonation of the carboxylic acid group of pravastatin." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:63618 ! is deprotonated form of pravastatin

[Term]
id: CHEBI:63667
name: dipyridodiazepine
def: "An organic heterotricyclic compound whose skeleton consists of a diazepine ring which is fused to two pyridine rings." []
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:6367
name: lamotrigine
def: "A member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:39410 ! 1,2,4-triazines
is_a: CHEBI:50471 ! primary arylamine
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35477 ! has role antimanic drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:60798 ! has role excitatory amino acid antagonist
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:63677
name: erythromycin D(1+)
def: "An erythromycin cation resulting from the protonation of the tertiary amino group of erythromycin D; the major species at pH 7.3." []
is_a: CHEBI:64290 ! erythromycin cation
relationship: RO:0018034 CHEBI:28331 ! is protonated form of erythromycin D

[Term]
id: CHEBI:63717
name: tenofovir disoproxil
def: "An organic phosphonate that is the disoproxil ester of tenofovir. A prodrug for tenofovir, an HIV-1 reverse transcriptase inhibitor, tenofovir disoproxil is used as the fumaric acid salt in combination therapy for the treatment of HIV infection." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26401 ! purines
is_a: CHEBI:37592 ! organic phosphonate
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0018038 CHEBI:63625 ! has functional parent tenofovir (anhydrous)

[Term]
id: CHEBI:63718
name: tenofovir disoproxil fumarate
def: "A fumarate salt prepared from equimolar amounts of tenofovir disoproxil and fumaric acid. It is used in combination therapy for the treatment of HIV infection." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26401 ! purines
is_a: CHEBI:50921 ! fumarate salt
relationship: BFO:0000051 CHEBI:63717 ! has part tenofovir disoproxil
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:53756 ! has role HIV-1 reverse transcriptase inhibitor
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent

[Term]
id: CHEBI:63720
name: EC 2.1.1.45 (thymidylate synthase) inhibitor
def: "An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of thymidylate synthase (EC 2.1.1.45)." []
is_a: CHEBI:76871 ! EC 2.1.1.* (methyltransferases) inhibitor

[Term]
id: CHEBI:63721
name: EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
def: "An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)." []
is_a: CHEBI:76874 ! EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor

[Term]
id: CHEBI:63724
name: pemetrexed(2-)
def: "A dicarboxylic acid dianion obtained by deprotonation of both carboxy groups of pemetrexed." []
is_a: CHEBI:28965 ! dicarboxylic acid dianion
is_a: CHEBI:59874 ! N-acyl-L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:63616 ! is deprotonated form of pemetrexed

[Term]
id: CHEBI:63726
name: neuroprotective agent
def: "Any compound that can be used for the treatment of neurodegenerative disorders." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:63732
name: 1,1-diol
def: "Any alcohol in which two hydroxy groups are bonded to the same atom." []
is_a: CHEBI:30879 ! alcohol

[Term]
id: CHEBI:63733
name: aldehyde hydrate
def: "A 1,1-diol resulting from the formal addition of water to the carbonyl group of a aldehyde." []
is_a: CHEBI:63732 ! 1,1-diol

[Term]
id: CHEBI:63791
name: lenalidomide
def: "A dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-α." []
is_a: CHEBI:24897 ! isoindoles
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35356 ! dicarboximide
is_a: CHEBI:48589 ! piperidones
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:63794
name: retinoid X receptor agonist
def: "An agonist that selectively binds to and activates a retinoid X receptor." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:63894
name: pivalate
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of pivalic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:45133 ! is deprotonated form of pivalic acid

[Term]
id: CHEBI:63895
name: ionic liquid
def: "Any salt, particularly one with a low melting point, that can be used in the liquid phase as a solvent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24866 ! salt
relationship: RO:0000087 CHEBI:48354 ! has role polar solvent

[Term]
id: CHEBI:63920
name: artemisinin derivative
def: "Any organic peroxide formally obtained from artemisinin." []
is_a: CHEBI:25702 ! organic peroxide
relationship: RO:0018038 CHEBI:223316 ! has functional parent (+)-artemisinin

[Term]
id: CHEBI:63921
name: 2-butoxyethanol
def: "A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group. A high-boiling (171°C) colourless liquid, it is used as a solvent for paints and inks, as well as in some dry cleaning solutions." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:172390 ! glycol ether

[Term]
id: CHEBI:63933
name: Aroclor 1254
def: "A mixture of polychlorobiphenyls of unspecified composition, containing 54% chlorine (X = Cl or H)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:53156 ! has part polychlorobiphenyl
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:63941
name: 22,23-dihydroavermectin B1a
def: "A macrocyclic lactone that is avermectin B<small><sub>1a</sub></small> in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin." []
is_a: CHEBI:63944 ! macrocyclic lactone
is_a: CHEBI:72600 ! spiroketal
relationship: RO:0018038 CHEBI:29534 ! has functional parent avermectin B1a

[Term]
id: CHEBI:63943
name: 22,23-dihydroavermectin B1b
def: "A macrocyclic lactone that is avermectin B<small><sub>1b</sub></small> in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin." []
is_a: CHEBI:63944 ! macrocyclic lactone
is_a: CHEBI:72600 ! spiroketal
relationship: RO:0018038 CHEBI:29537 ! has functional parent avermectin B1b

[Term]
id: CHEBI:63944
name: macrocyclic lactone
def: "Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule." []
is_a: CHEBI:25000 ! lactone
is_a: CHEBI:51026 ! macrocycle

[Term]
id: CHEBI:63954
name: ionomycin
def: "A very long-chain fatty acid that is docosa-10,16-dienoic acid which is substituted by methyl groups at positions 4, 6, 8, 12, 14, 18 and 20, by hydroxy groups at positions 11, 19 and 21, and by a (2',5-dimethyloctahydro-2,2'-bifuran-5-yl)ethanol group at position 21. An ionophore produced by <em>Streptomyces conglobatus</em>, it is used in research to raise the intracellular level of Ca<small><sup>2+</small></sup> and as a research tool to understand Ca<small><sup>2+</small></sup> transport across biological membranes." []
is_a: CHEBI:26208 ! polyunsaturated fatty acid
is_a: CHEBI:27283 ! very long-chain fatty acid
is_a: CHEBI:33823 ! enol
is_a: CHEBI:37407 ! cyclic ether
relationship: RO:0000087 CHEBI:22986 ! has role calcium ionophore
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:63956
name: isoxaben
def: "A benzamide obtained by formal condensation of the carboxy group of 2,6-dimethoxybenzoic acid and the amino group of 3-(3-methylpentan-3-yl)-1,2-oxazol-5-amine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:55373 ! isoxazoles
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:63958 ! has role cellulose synthesis inhibitor

[Term]
id: CHEBI:63958
name: cellulose synthesis inhibitor
def: "An pathway inhibitor that inhibits the synthesis of cellulose." []
is_a: CHEBI:76932 ! pathway inhibitor

[Term]
id: CHEBI:63959
name: celastrol
def: "A pentacyclic triterpenoid that is 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid bearing an oxo substituent at position 2, a hydroxy substituent at position 3 and two methyl groups at positions 9 and 13. An antioxidant and anti-inflammatory agent. Potently inhibits lipid peroxidation in mitochondria and inhibits TNF-α-induced NFκB activation. Also shown to inhibit topoisomerase II activity in vitro (IC50 = 7.41 μM)." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:25872 ! pentacyclic triterpenoid
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:63962 ! has role Hsp90 inhibitor

[Term]
id: CHEBI:63962
name: Hsp90 inhibitor
def: "An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90." []
is_a: CHEBI:76939 ! EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor

[Term]
id: CHEBI:64009
name: hydroperoxy fatty acid
def: "Any fatty acid carrying one or more hydroperoxy substituents." []
is_a: CHEBI:35366 ! fatty acid
is_a: CHEBI:61051 ! lipid hydroperoxide
relationship: RO:0018034 CHEBI:64012 ! is protonated form of hydroperoxy fatty acid anion

[Term]
id: CHEBI:64012
name: hydroperoxy fatty acid anion
def: "A fatty acid anion that is the conjugate base of any hydroperoxy fatty acid, formed by deprotonation of the carboxylic acid moiety." []
is_a: CHEBI:28868 ! fatty acid anion
relationship: RO:0018033 CHEBI:64009 ! is deprotonated form of hydroperoxy fatty acid

[Term]
id: CHEBI:64018
name: protein kinase C agonist
def: "An agonist that selectively binds to and activates a protein kinase C receptor" []
is_a: CHEBI:64106 ! protein kinase agonist

[Term]
id: CHEBI:64019
name: 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
def: "A member of the class of chromanes that is 2,2'-iminodiethanol in which one hydrogen attached to each hydroxy-bearing carbon is replaced by a  6-fluorochroman-2-yl group." []
is_a: CHEBI:23230 ! chromanes
is_a: CHEBI:23824 ! diol
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:50995 ! secondary amino compound

[Term]
id: CHEBI:6402
name: leflunomide
def: "A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:55373 ! isoxazoles
is_a: CHEBI:62733 ! aromatic amide
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:37153 ! has role EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:68542 ! has role EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor
relationship: RO:0000087 CHEBI:68543 ! has role pyrimidine synthesis inhibitor

[Term]
id: CHEBI:64020
name: (R,S,S,S)-nebivolol
def: "A 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2<em>H</em>-chromen-2-yl)ethanol] that has (1<i>S</i>,1'<i>S</i>,2<i>R</i>,2'<i>S</i>)-configuration." []
is_a: CHEBI:64019 ! 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
relationship: RO:0018033 CHEBI:132915 ! is deprotonated form of (R,S,S,S)-nebivolol(1+)
relationship: RO:0018039 CHEBI:64021 ! is enantiomer of (S,R,R,R)-nebivolol

[Term]
id: CHEBI:64021
name: (S,R,R,R)-nebivolol
def: "A 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2<em>H</em>-chromen-2-yl)ethanol] that has (1<i>R</i>,1'<i>R</i>,2<i>R</i>,2'<i>S</i>)-configuration." []
is_a: CHEBI:64019 ! 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
relationship: RO:0018033 CHEBI:132916 ! is deprotonated form of (S,R,R,R)-nebivolol(1+)
relationship: RO:0018039 CHEBI:64020 ! is enantiomer of (R,S,S,S)-nebivolol

[Term]
id: CHEBI:64022
name: nebivolol
def: "A racemate consisting of equal amounts of (<i>R</i>,<i>S</i>,<i>S</i>,<i>S</i>)-nebivolol and (<i>S</i>,<i>R</i>,<i>R</i>,<i>R</i>)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:64020 ! has part (R,S,S,S)-nebivolol
relationship: BFO:0000051 CHEBI:64021 ! has part (S,R,R,R)-nebivolol
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent

[Term]
id: CHEBI:64045
name: amisulpride
def: "A member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D<small><sub>2</sub></small> and D<small><sub>3</sub></small> receptor antagonist. It is an atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects." []
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35850 ! sulfone
is_a: CHEBI:38260 ! pyrrolidines
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:64047
name: food additive
def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." []
is_a: CHEBI:747325 ! additive
is_a: CHEBI:78295 ! food component

[Term]
id: CHEBI:64049
name: food acidity regulator
def: "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:64051
name: dibenzodiazepine
def: "Any organic heterotricyclic compound with a skeleton consisting of two benzene rings fused to a diazepine ring." []
is_a: CHEBI:26979 ! organic heterotricyclic compound

[Term]
id: CHEBI:64054
name: delta-opioid receptor agonist
def: "A compound that exhibits agonist activity at the δ-opioid receptor." []
is_a: CHEBI:60601 ! delta-opioid agent
is_a: CHEBI:60606 ! opioid receptor agonist

[Term]
id: CHEBI:6407
name: lenacil
def: "A cyclopentapyrimidine that is 6,7-dihydro-1<em>H</em>-cyclopenta[<em>d</em>]pyrimidine-2,4(3<em>H</em>,5<em>H</em>)-dione substituted by a cyclohexyl group at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48437 ! cyclopentapyrimidine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:64090
name: tert-butyl hydroperoxide
def: "An alkyl hydroperoxide in which the alkyl group is <em>tert</em>-butyl. It is widely used in a variety of oxidation processes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:61050 ! alkyl hydroperoxide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent

[Term]
id: CHEBI:64096
name: benzodioxine
def: "Any organic heterobicyclic compound containing <em>ortho</em>-fused benzene and dioxine rings." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38104 ! oxacycle

[Term]
id: CHEBI:64103
name: sodium butyrate
def: "An organic sodium salt resulting from the replacement of the proton from the carboxy group of butyric acid by a sodium ion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:61697 ! fatty acid derivative
relationship: BFO:0000051 CHEBI:17968 ! has part butyrate
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor

[Term]
id: CHEBI:64106
name: protein kinase agonist
def: "An agonist that selectively binds to and activates a protein kinase receptor." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:64124
name: phytosphingosine(1+)
def: "A cationic sphingoid that is the conjugate acid of phytosphingosine, obtained by protonation of the primary amino function; major species at pH 7.3." []
is_a: CHEBI:84410 ! sphingoid base(1+)
relationship: RO:0018034 CHEBI:46961 ! is protonated form of phytosphingosine

[Term]
id: CHEBI:6413
name: letrozole
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:51614 ! diarylmethane
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50790 ! has role EC 1.14.14.14 (aromatase) inhibitor

[Term]
id: CHEBI:64133
name: EC 2.5.1.58 (protein farnesyltransferase) inhibitor
def: "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group." []
is_a: CHEBI:76663 ! EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor

[Term]
id: CHEBI:64152
name: cysteine protease inhibitor
def: "Any protease inhibitor that restricts the action of a cysteine protease." []
is_a: CHEBI:37670 ! protease inhibitor
is_a: CHEBI:76796 ! EC 3.4.22.* (cysteine endopeptidase) inhibitor

[Term]
id: CHEBI:64163
name: diquat
def: "The organic cation formed formally by addition of an ethylene bridge between the nitrogen atoms of 2,2'-bipyridine. Most often available as the dibromide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25697 ! organic cation
relationship: RO:0000087 CHEBI:23582 ! has role defoliant
relationship: RO:0018040 CHEBI:30351 ! has parent hydride 2,2'-bipyridine

[Term]
id: CHEBI:64197
name: paroxetinium(1+)
def: "An organic cation that is the conjugate acid of paroxetine, arising from protonation of the piperidine nitrogen." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:7936 ! is protonated form of paroxetine

[Term]
id: CHEBI:64214
name: sertraline(1+)
def: "An ammonium ion resulting from the protonation of the amino group of sertraline." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:9123 ! is protonated form of sertraline

[Term]
id: CHEBI:64220
name: monosodium glutamate
def: "An organic sodium salt that is the monosodium salt of glutamic acid." []
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:14321 ! has part glutamate(1-)

[Term]
id: CHEBI:64228
name: tunicamycin A0
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64237
name: EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor
def: "An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-<em>N</em>-acetylglucosamine—dolichyl-phosphate <em>N</em>-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of <em>N</em>-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins." []
is_a: CHEBI:76816 ! EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor

[Term]
id: CHEBI:64243
name: monosodium L-glutamate
def: "An optically active form of monosodium glutamate having <small>L</small>-configuration." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:64220 ! monosodium glutamate
relationship: BFO:0000051 CHEBI:29985 ! has part L-glutamate(1-)
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0018039 CHEBI:64244 ! is enantiomer of monosodium D-glutamate

[Term]
id: CHEBI:64244
name: monosodium D-glutamate
def: "An optically active form of monosodium glutamate having <small>D</small>-configuration." []
is_a: CHEBI:64220 ! monosodium glutamate
relationship: BFO:0000051 CHEBI:29986 ! has part D-glutamate(1-)
relationship: RO:0018039 CHEBI:64243 ! is enantiomer of monosodium L-glutamate

[Term]
id: CHEBI:64245
name: tunicamycin A1
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64246
name: tunicamycin A2
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64248
name: tunicamycin B1
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64250
name: tunicamycin B2
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64255
name: tunicamycin B3
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64256
name: tunicamycin C1
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0000087 CHEBI:76507 ! has role marine metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:64257
name: tunicamycin C2
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64258
name: erythromycin C(1+)
def: "An erythromycin cation that is the conjugate acid of erythromycin C, arising from protonation of the tertiary amino group on the 3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-<i>xylo</i>-hexopyranosyl residue; major species at pH 7.3." []
is_a: CHEBI:64290 ! erythromycin cation
relationship: RO:0018034 CHEBI:64273 ! is protonated form of erythromycin C

[Term]
id: CHEBI:64268
name: erythromycin A(1+)
def: "An erythromycin cation that is the conjugate acid of erythromycin A, arising from protonation of the tertiary amino group on the 3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-<i>xylo</i>-hexopyranosyl residue; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:64290 ! erythromycin cation
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0018034 CHEBI:42355 ! is protonated form of erythromycin A

[Term]
id: CHEBI:64271
name: tunicamycin D1
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64272
name: tunicamycin D2
def: "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33838 ! nucleoside
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:64273
name: erythromycin C
def: "An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-<em>C</em>-methyl-α-<small>L</small>-<i>ribo</i>-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-β-<small>D</small>-<i>xylo</i>-hexopyranosyl residues attahced at positions 4 and 6 respectively." []
is_a: CHEBI:48923 ! erythromycin
relationship: RO:0018033 CHEBI:64258 ! is deprotonated form of erythromycin C(1+)
relationship: RO:0018038 CHEBI:48848 ! has functional parent erythronolide A

[Term]
id: CHEBI:64276
name: glutaraldehyde
def: "A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5." []
synonym: "PENTANEDIAL" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38124 ! dialdehyde
relationship: RO:0000087 CHEBI:48219 ! has role disinfectant
relationship: RO:0000087 CHEBI:50684 ! has role cross-linking reagent
relationship: RO:0000087 CHEBI:50913 ! has role fixative

[Term]
id: CHEBI:64290
name: erythromycin cation
def: "An organic cation obtained by protonation of any erythromycin." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018033 CHEBI:48923 ! is deprotonated form of erythromycin

[Term]
id: CHEBI:64301
name: calcium cyanamide
def: "The calcium salt of cyanamide, formed when calcium carbide reacts with nitrogen" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35156 ! calcium salt
is_a: CHEBI:53091 ! carbodiimide
relationship: BFO:0000051 CHEBI:64302 ! has part cyanamide(2-)
relationship: RO:0000087 CHEBI:33287 ! has role fertilizer

[Term]
id: CHEBI:64302
name: cyanamide(2-)
def: "An organic nitrogen anion formed from cyanamide by loss of its two protons." []
is_a: CHEBI:50335 ! organic nitrogen anion
relationship: RO:0018033 CHEBI:16698 ! is deprotonated form of cyanamide

[Term]
id: CHEBI:64310
name: crizotinib
def: "A  3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has <i>R</i> configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)" []
is_a: CHEBI:46699 ! pyrazolopyridine
is_a: CHEBI:77562 ! 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:62434 ! has role EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
relationship: RO:0018039 CHEBI:77555 ! is enantiomer of ent-crizotinib

[Term]
id: CHEBI:64312
name: memantine
def: "A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels." []
is_a: CHEBI:17062 ! primary aliphatic amine
is_a: CHEBI:51339 ! adamantanes
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:48560 ! has role dopaminergic agent
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018033 CHEBI:64325 ! is deprotonated form of memantinium(1+)
relationship: RO:0018040 CHEBI:40519 ! has parent hydride adamantane

[Term]
id: CHEBI:64317
name: isoprenaline
def: "A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on β-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders." []
is_a: CHEBI:33566 ! catechols
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:35523 ! has role bronchodilator agent
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:38147 ! has role cardiotonic drug

[Term]
id: CHEBI:6432
name: levamisole
def: "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-<em>b</em>][1,3]thiazole that has <i>S</i> configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine." []
is_a: CHEBI:77278 ! 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
relationship: RO:0000087 CHEBI:35444 ! has role antinematodal drug
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant
relationship: RO:0000087 CHEBI:63332 ! has role EC 3.1.3.1 (alkaline phosphatase) inhibitor
relationship: RO:0018039 CHEBI:77282 ! is enantiomer of dexamisole

[Term]
id: CHEBI:64325
name: memantinium(1+)
def: "An organic cation that is the conjugate acid of memantine obtained by protonation of the primary amino function." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:64312 ! is protonated form of memantine

[Term]
id: CHEBI:64345
name: MALDI matrix material
def: "A compound used to form the matrix for MALDI (matrix-assisted laser desorption/ionization) mass spectrometry. MALDI matrix materials are crystalline compounds with a fairly low molecular weight, so as to allow facile vaporization, have strong absorption at UV or IR wavelengths (to rapidly and efficiently absorb laser irradiation), generally contain polar groups (enabling them to be used in aqueous solutions) and are frequently acidic (so assisting ionisation of the compound being studied, which is contained within the matrix material)." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:64365
name: aralkylamino compound
def: "An organic amino compound in which an aminoalkyl group is linked to an arene." []
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:6437
name: levetiracetam
def: "A pyrrolidinone and carboxamide that is <em>N</em>-methylpyrrolidin-2-one in which one of the methyl hydrogens is replaced by an aminocarbonyl group, while another is replaced by an ethyl group (the <i>S</i> enantiomer). An anticonvulsant, it is used for the treatment of epilepsy in both human and veterinary medicine." []
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:74223 ! pyrrolidin-2-ones
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:64370
name: glutamate transporter activator
def: "A neurotransmitter transporter modulator that activates glutamate transporters." []
is_a: CHEBI:64371 ! neurotransmitter transporter modulator

[Term]
id: CHEBI:64371
name: neurotransmitter transporter modulator
def: "A membrane transport modulator that affects the transport of neurotransmitters." []
is_a: CHEBI:35942 ! neurotransmitter agent
is_a: CHEBI:38632 ! membrane transport modulator

[Term]
id: CHEBI:64382
name: organosulfonate salt
def: "Any organic salt prepared using an organosulfonic acid as the acid component." []
is_a: CHEBI:24868 ! organic salt
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:64406
name: EC 3.4.22.38 (cathepsin K) inhibitor
def: "A cysteine protease inhibitor which inhibits cathepsin K (EC 3.4.22.38)." []
is_a: CHEBI:64152 ! cysteine protease inhibitor

[Term]
id: CHEBI:64411
name: EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor
def: "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of geranylgeranyl diphosphate synthase (EC 2.5.1.29)." []
is_a: CHEBI:76663 ! EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor

[Term]
id: CHEBI:64416
name: EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
def: "An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43)." []
is_a: CHEBI:76857 ! EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:6443
name: levonorgestrel
def: "The (−)-enantiomer of norgestrel." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:231594 ! 17-ethynyl-17-hydroxy-18a-homoestr-4-en-3-one
is_a: CHEBI:35343 ! 17beta-hydroxy steroid
is_a: CHEBI:36834 ! 3-hydroxy steroid
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:49326 ! has role synthetic oral contraceptive
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:59826 ! has role progestin
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0018039 CHEBI:50900 ! is enantiomer of dextronorgestrel

[Term]
id: CHEBI:6444
name: Levorphanol
is_a: CHEBI:25418 ! morphinane alkaloid

[Term]
id: CHEBI:64448
name: arsonate(1-)
def: "The arsenic oxoanion formed by loss os a single proton from arsonic acid." []
is_a: CHEBI:35776 ! arsenic oxoanion
relationship: RO:0018033 CHEBI:29850 ! is deprotonated form of arsonic acid
relationship: RO:0018034 CHEBI:29754 ! is protonated form of arsonate(2-)

[Term]
id: CHEBI:64459
name: biaryl
def: "An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond." []
is_a: CHEBI:33659 ! organic aromatic compound

[Term]
id: CHEBI:64477
name: monolignol
def: "A metabolite of plant origin (phytochemical) which acts as a source material for biosynthesis of both lignans and lignin." []
is_a: CHEBI:76924 ! plant metabolite

[Term]
id: CHEBI:64513
name: thianthrenes
def: "An organic heterotricyclic compound containing a thianthrene skeleton." []
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:38106 ! organosulfur heterocyclic compound

[Term]
id: CHEBI:64554
name: tryptophan zwitterion
def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of tryptophan; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:27897 ! is tautomer of tryptophan

[Term]
id: CHEBI:64558
name: methionine zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of methionine; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:16811 ! is tautomer of methionine

[Term]
id: CHEBI:6456
name: lidocaine
def: "The monocarboxylic acid amide resulting from the formal condensation of <em>N</em>,<em>N</em>-diethylglycine with 2,6-dimethylaniline." []
is_a: CHEBI:22475 ! amino acid amide
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:36333 ! has role local anaesthetic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:42843 ! has functional parent glycinamide

[Term]
id: CHEBI:6457
name: lignin
def: "A polyphenylpropanoid derived from three monolignol monomers: <i>trans</i>-<em>p</em>-coumaryl alcohol, coniferol and <i>trans</i>-sinapyl alcohol. There is extensive cross-linking and no defined primary structure." []
is_a: CHEBI:26196 ! polyphenylpropanoid

[Term]
id: CHEBI:64570
name: EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor
def: "An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1)." []
is_a: CHEBI:76874 ! EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor

[Term]
id: CHEBI:64571
name: NMDA receptor agonist
def: "An excitatory amino acid agonist which binds to NMDA receptors and triggers a response." []
is_a: CHEBI:50103 ! excitatory amino acid agonist

[Term]
id: CHEBI:64577
name: flour treatment agent
def: "A food additive which is added to flour or dough to improve baking quality and/or colour." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:64584
name: uremic toxin
def: "A toxin that accumulates in patients with chronic kidney disease." []
is_a: CHEBI:27026 ! toxin

[Term]
id: CHEBI:64588
name: glycine transporter 1 inhibitor
def: "Any glycine transporter inhibitor that interferes with the action of glycine 1 transporters." []
is_a: CHEBI:85425 ! glycine transporter inhibitor

[Term]
id: CHEBI:64589
name: glycine receptor agonist
def: "An agonist that binds to and activates glycine receptors" []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:64598
name: 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
def: "A differentiation-inducing factor that is hexaphenone bearing two chloro substituents at positions 3 and 5, two hydroxy substituents at positions 2 and 6 as well as a single methoxy substituent at position 4. A secreted, chlorinated molecule that controls cell fate during development of <em>Dictyostelium</em> cells." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:33572 ! resorcinols
is_a: CHEBI:64672 ! differentiation-inducing factor
relationship: RO:0000087 CHEBI:62488 ! has role signalling molecule
relationship: RO:0018034 CHEBI:90397 ! is protonated form of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one(1-)
relationship: RO:0018038 CHEBI:90396 ! has functional parent (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one

[Term]
id: CHEBI:64600
name: C21-steroid hormone
def: "A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone." []
is_a: CHEBI:26764 ! steroid hormone
is_a: CHEBI:61313 ! C21-steroid

[Term]
id: CHEBI:64611
name: ether lipid
def: "A lipid similar in structure to a glycerolipid but in which one or more of the carbon atoms on glycerol is bonded to an alkyl chain via an ether linkage, as opposed to the usual ester linkage." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:52575 ! alkylglycerol

[Term]
id: CHEBI:64637
name: O-polysaccharide
def: "A repetitive glycan polysaccharide contained within a lipopolysaccharide (LPS). The <em>O</em>-antigen is attached to the core oligosaccharide, and comprises the outermost domain of the LPS molecule." []
is_a: CHEBI:65212 ! polysaccharide derivative

[Term]
id: CHEBI:64641
name: divalent inorganic cation
def: "An inorganic cation with a valency of two." []
is_a: CHEBI:36915 ! inorganic cation

[Term]
id: CHEBI:64645
name: amyloid-beta
def: "A peptide of 36-43 amino acids that is processed from the amyloid precursor protein. Appears to be the main constituent of amyloid plaques (deposits found in the brains of Alzheimer's disease patients)." []
is_a: CHEBI:15841 ! polypeptide

[Term]
id: CHEBI:64669
name: 2-hydroxy-3-methylbutyrate
def: "A hydroxy monocarboxylic acid anion that is the conjugate base of 2-hydroxy-3-methylbutyric acid, formed by loss of a proton from the carboxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:60645 ! is deprotonated form of 2-hydroxy-3-methylbutyric acid

[Term]
id: CHEBI:64670
name: EC 1.8.1.9 (thioredoxin reductase) inhibitor
def: "An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of thioredoxin reductase (EC 1.8.1.9)." []
is_a: CHEBI:76869 ! EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:64672
name: differentiation-inducing factor
def: "An aromatic ketone that is penta- or hexaphenone bearing chloro, hydroxy and methoxy substituents on the benzene ring. A class of effector molecules isolated from <em>Dictyostelium discoideum</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:51683 ! methoxybenzenes
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:35224 ! has role effector
relationship: RO:0000087 CHEBI:75763 ! has role eukaryotic metabolite

[Term]
id: CHEBI:64677
name: daunorubicin(1+)
def: "An anthracycline cation that is the conjugate acid of daunorubicin, arising from protonation of the amino group." []
is_a: CHEBI:64678 ! anthracycline cation
relationship: RO:0018034 CHEBI:41977 ! is protonated form of daunorubicin

[Term]
id: CHEBI:64678
name: anthracycline cation
def: "An organic cation obtained by protonation of any anthracycline." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:48120 ! is protonated form of anthracycline

[Term]
id: CHEBI:64682
name: metronidazole(1+)
def: "An organic cation resulting from the addition of a proton to metronidazole." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:6909 ! is protonated form of metronidazole

[Term]
id: CHEBI:64708
name: one-carbon compound
def: "An organic molecular entity containing a single carbon atom (C<small><sub>1</sub></small>)." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:64709
name: organic acid
def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:64712
name: trivalent inorganic cation
def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of three." []
is_a: CHEBI:36915 ! inorganic cation

[Term]
id: CHEBI:6472
name: lincomycin
def: "A carbohydrate-containing antibiotic produced by the actinomyces <em>Streptomyces lincolnensis</em>." []
is_a: CHEBI:23007 ! carbohydrate-containing antibiotic
is_a: CHEBI:35275 ! S-glycosyl compound
is_a: CHEBI:46770 ! pyrrolidinecarboxamide
is_a: CHEBI:84186 ! L-proline derivative
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:64734
name: EDTA disodium salt (anhydrous)
def: "An organic sodium salt that is the anhydrous form of the disodium salt of ethylenediaminetetraacetic acid (EDTA)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:64755 ! has part EDTA(2-)
relationship: RO:0000087 CHEBI:38161 ! has role chelator

[Term]
id: CHEBI:64755
name: EDTA(2-)
def: "A tetracarboxylic acid anion formed by deprotonation of two of the four carboxy groups in ethylenediaminetetraacetic acid (EDTA)." []
is_a: CHEBI:35754 ! tetracarboxylic acid anion
relationship: RO:0018033 CHEBI:4735 ! is deprotonated form of ethylenediaminetetraacetic acid
relationship: RO:0018034 CHEBI:63131 ! is protonated form of EDTA(3-)

[Term]
id: CHEBI:64763
name: EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
def: "An  EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C (EC 3.1.4.11)." []
is_a: CHEBI:50218 ! EC 3.1.4.* (phosphoric diester hydrolase) inhibitor

[Term]
id: CHEBI:64766
name: cationic group
def: "A group that carries an overall positive charge." []
is_a: CHEBI:24433 ! group

[Term]
id: CHEBI:64767
name: anionic group
def: "A group that carries an overall negative charge." []
is_a: CHEBI:24433 ! group

[Term]
id: CHEBI:64769
name: organic cationic group
def: "A cationic group that contains carbon." []
is_a: CHEBI:64766 ! cationic group
relationship: RO:0018034 CHEBI:33247 ! is protonated form of organic group

[Term]
id: CHEBI:64775
name: organic anionic group
def: "An anionic group that contains carbon." []
is_a: CHEBI:64767 ! anionic group
relationship: RO:0018033 CHEBI:33247 ! is deprotonated form of organic group

[Term]
id: CHEBI:64816
name: doxorubicin(1+)
def: "An anthracycline cation that is the conjugate acid of doxorubicin, arising from protonation of the amino group; major species at pH 7.3." []
is_a: CHEBI:64678 ! anthracycline cation
relationship: RO:0018034 CHEBI:28748 ! is protonated form of doxorubicin

[Term]
id: CHEBI:6482
name: linuron
def: "A member of the class of phenylureas that is <em>N</em>-methyl urea substituted by a methoxy group at position 1 and a 3,4-dichlorophenyl group at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134043 ! phenylureas
is_a: CHEBI:23697 ! dichlorobenzene
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:44383 ! has functional parent N-methyl urea

[Term]
id: CHEBI:64857
name: cosmetic
def: "The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:64898
name: anionic amino-acid residue
def: "An amino-acid residue carrying an overall negative charge." []
is_a: CHEBI:64775 ! organic anionic group
relationship: RO:0018033 CHEBI:33708 ! is deprotonated form of amino-acid residue

[Term]
id: CHEBI:64909
name: poison
def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:64911
name: antimitotic
def: "Any compound that inhibits cell division (mitosis)." []
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:64912
name: antimycobacterial drug
def: "A drug used to treat or prevent infections caused by <em>Mycobacteria</em>, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy." []
is_a: CHEBI:36047 ! antibacterial drug

[Term]
id: CHEBI:64915
name: antiplasmodial drug
def: "An antiparasitic drug which is effective against Apicomplexan parasites in the genus <em>Plasmodium</em>. The genus contains over 200 species and includes those responsible for malaria." []
is_a: CHEBI:35820 ! antiprotozoal drug

[Term]
id: CHEBI:64926
name: serine protease inhibitor
def: "Any protease inhibitor that restricts the action of a serine protease." []
is_a: CHEBI:37670 ! protease inhibitor

[Term]
id: CHEBI:64933
name: melanin synthesis inhibitor
def: "A depigmentation agent which inhibits the synthesis of melanin." []
is_a: CHEBI:59864 ! depigmentation drug

[Term]
id: CHEBI:64946
name: anti-HIV agent
def: "An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus." []
is_a: CHEBI:22587 ! antiviral agent

[Term]
id: CHEBI:64947
name: anti-HIV-1 agent
def: "An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus." []
is_a: CHEBI:64946 ! anti-HIV agent

[Term]
id: CHEBI:64948
name: pyrrolizidine alkaloid
def: "An alkaloid based on the structure of pyrrolizidine." []
is_a: CHEBI:22315 ! alkaloid
relationship: RO:0018040 CHEBI:64950 ! has parent hydride pyrrolizidine

[Term]
id: CHEBI:6495
name: lipoprotein
def: "A clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33837 ! conjugated protein
is_a: CHEBI:39024 ! clathrate compound
relationship: BFO:0000051 CHEBI:39015 ! has part apolipoprotein
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite

[Term]
id: CHEBI:64950
name: pyrrolizidine
def: "A bicyclic organonitrogen heterocyclic compound comprised of two <em>ortho</em>-fused pyrrolidine rings which share a common nitrogen atom." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:64951
name: anti-HBV agent
def: "An antiviral agent that destroys or inhibits the replication of the hepatitis B virus." []
is_a: CHEBI:22587 ! antiviral agent

[Term]
id: CHEBI:64952
name: anti-HSV agent
def: "An antiviral agent that destroys or inhibits the replication of the herpes simplex virus (also known as the human herpes virus)." []
is_a: CHEBI:22587 ! antiviral agent

[Term]
id: CHEBI:64953
name: anti-HSV-1 agent
def: "An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-1." []
is_a: CHEBI:64952 ! anti-HSV agent

[Term]
id: CHEBI:64964
name: EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
def: "A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34)." []
is_a: CHEBI:35856 ! lipoxygenase inhibitor

[Term]
id: CHEBI:64986
name: benzochromenone
def: "A benzochromene in which the heterotricyclic ring system is substituted by an oxo group." []
is_a: CHEBI:38920 ! benzochromene

[Term]
id: CHEBI:64996
name: EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
def: "A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33)." []
is_a: CHEBI:35856 ! lipoxygenase inhibitor

[Term]
id: CHEBI:65001
name: EC 3.1.1.3 (triacylglycerol lipase) inhibitor
def: "Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3)." []
is_a: CHEBI:76773 ! EC 3.1.1.* (carboxylic ester hydrolase) inhibitor

[Term]
id: CHEBI:65023
name: anti-asthmatic agent
def: "Any compound that has anti-asthmatic effects." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:6504
name: lithium carbonate
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35478 ! lithium salt
is_a: CHEBI:46721 ! carbonate salt
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35477 ! has role antimanic drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug

[Term]
id: CHEBI:65053
name: EC 4.1.1.19 (arginine decarboxylase) inhibitor
def: "An  EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of arginine decarboxylase (EC 4.1.1.19)." []
is_a: CHEBI:76906 ! EC 4.1.1.* (carboxy-lyase) inhibitor

[Term]
id: CHEBI:65056
name: EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
def: "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11)." []
is_a: CHEBI:76775 ! EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor

[Term]
id: CHEBI:65057
name: adenosine A1 receptor agonist
def: "An agonist at the A<small><sub>1</sub></small> receptor." []
is_a: CHEBI:73311 ! adenosine receptor agonist

[Term]
id: CHEBI:65064
name: EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor
def: "An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of cyclopropane fatty acid synthase (EC 2.1.1.79)." []
is_a: CHEBI:76871 ! EC 2.1.1.* (methyltransferases) inhibitor

[Term]
id: CHEBI:65065
name: EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor
def: "An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of site-specific DNA-methyltransferase (adenine-specific), EC 2.1.1.72." []
is_a: CHEBI:76871 ! EC 2.1.1.* (methyltransferases) inhibitor

[Term]
id: CHEBI:65172
name: ximelagatran
def: "A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted into the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:38777 ! azetidines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:65234 ! amidoxime
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:64926 ! has role serine protease inhibitor
relationship: RO:0000087 CHEBI:65232 ! has role EC 3.4.21.5 (thrombin) inhibitor
relationship: RO:0018036 CHEBI:136702 ! is tautomer of ximelagatran (hydroxylamine form)
relationship: RO:0018038 CHEBI:43966 ! has functional parent melagatran

[Term]
id: CHEBI:65173
name: iloperidone
def: "A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia." []
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:51545 ! 1,2-benzoxazoles
is_a: CHEBI:51867 ! methyl ketone
is_a: CHEBI:63534 ! monoamine
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic

[Term]
id: CHEBI:65190
name: first generation antipsychotic
def: "Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased." []
is_a: CHEBI:35476 ! antipsychotic agent

[Term]
id: CHEBI:65191
name: second generation antipsychotic
def: "Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements." []
is_a: CHEBI:35476 ! antipsychotic agent

[Term]
id: CHEBI:65207
name: vascular endothelial growth factor receptor antagonist
def: "An antagonist at the vascular endothelial growth factor receptor." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:65212
name: polysaccharide derivative
def: "A carbohydrate derivative that is any derivative of a polysaccharide." []
is_a: CHEBI:167559 ! glycan
is_a: CHEBI:33694 ! biomacromolecule
is_a: CHEBI:63299 ! carbohydrate derivative
relationship: RO:0018038 CHEBI:18154 ! has functional parent polysaccharide

[Term]
id: CHEBI:65232
name: EC 3.4.21.5 (thrombin) inhibitor
def: "An  EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of thrombin (EC 3.4.21.5)." []
is_a: CHEBI:5924 ! EC 3.4.21.* (serine endopeptidase) inhibitor

[Term]
id: CHEBI:65234
name: amidoxime
def: "Amidines of general formula RC(=NOH)NR<small><sup>1</small></sup>R<small><sup>2</small></sup>, in which the imino nitrogen is substituted by a hydroxy group." []
is_a: CHEBI:2634 ! amidine

[Term]
id: CHEBI:65255
name: food preservative
def: "Substances which are added to food in order to prevent decomposition caused by  microbial growth or by undesirable chemical changes." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:65256
name: antimicrobial food preservative
def: "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." []
is_a: CHEBI:33281 ! antimicrobial agent
is_a: CHEBI:65255 ! food preservative

[Term]
id: CHEBI:65259
name: GABA antagonist
def: "A compound that inhibits the action of γ-aminobutyric acid." []
is_a: CHEBI:48706 ! antagonist
is_a: CHEBI:51374 ! GABA agent

[Term]
id: CHEBI:65265
name: antacid
def: "Any substance which is used to neutralise stomach acidity." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:65296
name: primary ammonium ion
def: "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:50994 ! is protonated form of primary amino compound

[Term]
id: CHEBI:65311
name: corticotropin-releasing hormone
def: "A family of peptide hormones derived from a 191-membered prehormone, secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. The first full sequence was discovered in sheep, those in rats and humans differ from the ovine sequence by 7 amino acids." []
is_a: CHEBI:15841 ! polypeptide
is_a: CHEBI:25905 ! peptide hormone
is_a: CHEBI:33694 ! biomacromolecule
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter

[Term]
id: CHEBI:6532
name: loperamide
def: "A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:51614 ! diarylmethane
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug
relationship: RO:0018033 CHEBI:86969 ! is deprotonated form of loperamide(1+)

[Term]
id: CHEBI:65321
name: terpenoid indole alkaloid
def: "An indole alkaloid which is biosynthesised from <small>L</small>-tryptophan and isoprenoid building blocks." []
is_a: CHEBI:38958 ! indole alkaloid

[Term]
id: CHEBI:65323
name: monoterpenoid indole alkaloid
def: "A terpenoid indole alkaloid which is biosynthesised from <small>L</small>-tryptophan and diisoprenoid (usually secolaganin) building blocks." []
is_a: CHEBI:65321 ! terpenoid indole alkaloid

[Term]
id: CHEBI:65326
name: pictrelisib
def: "A sulfonamide composed of indazole, morpholine, and methylsulfonyl-substituted piperazine rings bound to a thienopyrimidine ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:143212 ! thienopyrimidine
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:38769 ! indazoles
is_a: CHEBI:38785 ! morpholines
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50914 ! has role EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor

[Term]
id: CHEBI:6533
name: loperamide hydrochloride
def: "A hydrochloride obtained by combining loperamide with one equivalent of hydrochloric acid. Used for treatment of diarrhoea resulting from gastroenteritis or inflammatory bowel disease." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
is_a: CHEBI:51614 ! diarylmethane
relationship: BFO:0000051 CHEBI:86969 ! has part loperamide(1+)
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug

[Term]
id: CHEBI:65347
name: carfilzomib
def: "A synthetic tetrapeptide consisting of morpholin-4-acetyl, <small>L</small>-2-amino-4-phenylbutanoyl, <small>L</small>-leucyl and <small>L</small>-phenylalanyl residues joined in sequence with the C-terminus connected to the amino group of (2<em>S</em>)-2-amino-4-methyl-1-[(2<i>R</i>)-2-methyloxiran-2-yl]-1-oxopentan-1-one via an amide linkage. Used for the treatment of patients with multiple myeloma" []
is_a: CHEBI:15841 ! polypeptide
is_a: CHEBI:32955 ! epoxide
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:48030 ! tetrapeptide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:52726 ! has role proteasome inhibitor

[Term]
id: CHEBI:65349
name: mirabegron
def: "A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2-amino-1,3-thiazol-4-ylacetic acid with the anilino group of (1<i>R</i>)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol. Used for the treatment of overactive bladder syndrome." []
is_a: CHEBI:13248 ! anilide
is_a: CHEBI:23981 ! ethanolamines
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:38418 ! 1,3-thiazoles
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35846 ! has role renal agent

[Term]
id: CHEBI:6541
name: losartan
def: "A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:48420 ! biphenylyltetrazole
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:51451 ! has role endothelin receptor antagonist
relationship: RO:0000087 CHEBI:61016 ! has role angiotensin receptor antagonist
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0018034 CHEBI:149504 ! is protonated form of losartan(1-)

[Term]
id: CHEBI:6650
name: malic acid
def: "A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group." []
is_a: CHEBI:50263 ! 2-hydroxydicarboxylic acid
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:66873 ! C4-dicarboxylic acid
relationship: RO:0000087 CHEBI:64049 ! has role food acidity regulator
relationship: RO:0000087 CHEBI:78675 ! has role fundamental metabolite
relationship: RO:0018034 CHEBI:15595 ! is protonated form of malate(2-)
relationship: RO:0018038 CHEBI:15741 ! has functional parent succinic acid

[Term]
id: CHEBI:6651
name: malathion
def: "A racemate comprising equimolar amounts of (<i>R</i>) and (<i>S</i>)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including <em>Coleoptera</em>, <em>Diptera</em>, fruit flies, mosquitos and spider mites." []
is_a: CHEBI:25715 ! organothiophosphate insecticide
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:141475 ! has part (R)-malathion
relationship: BFO:0000051 CHEBI:141476 ! has part (S)-malathion
relationship: RO:0000087 CHEBI:136644 ! has role proinsecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38706 ! has role pediculicide
relationship: RO:0000087 CHEBI:73333 ! has role scabicide

[Term]
id: CHEBI:66682
name: maslinic acid
def: "A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2α,3β stereoisomer). It is isolated from <em>Olea europaea</em> and <em>Salvia canariensis</em> and exhibits anti-inflammatory, antioxidant and antineoplastic activity." []
is_a: CHEBI:25872 ! pentacyclic triterpenoid
is_a: CHEBI:35972 ! dihydroxy monocarboxylic acid
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018040 CHEBI:36481 ! has parent hydride oleanane

[Term]
id: CHEBI:66873
name: C4-dicarboxylic acid
def: "Any dicarboxylic acid that contains four carbon atoms." []
is_a: CHEBI:35692 ! dicarboxylic acid
relationship: RO:0018034 CHEBI:61336 ! is protonated form of C4-dicarboxylate

[Term]
id: CHEBI:66884
name: N-alkylglycine zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of any <em>N</em>-alkylglycine; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:66933 ! is tautomer of N-alkylglycine
relationship: RO:0018038 CHEBI:57305 ! has functional parent glycine zwitterion

[Term]
id: CHEBI:66891
name: 5-nitro-o-toluidine
def: "A <em>C</em>-nitro compound in which the nitro compound is <em>meta</em> to the amino group and <em>para</em> to the methyl group of <em>o</em>-toluidine." []
is_a: CHEBI:35716 ! C-nitro compound
relationship: RO:0018038 CHEBI:66892 ! has functional parent o-toluidine

[Term]
id: CHEBI:66892
name: o-toluidine
def: "An aminotoluene in which the amino substituent is <em>ortho</em> to the methyl group." []
is_a: CHEBI:22531 ! aminotoluene
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:66910
name: axitinib
def: "An indazole substituted at position 3 by a 2-(pyridin-2-yl)vinyl group and at position 6 by a 2-(<em>N</em>-methylaminocarboxy)phenylsulfanyl group. Used for the treatment of advanced renal cell carcinoma after failure of a first line systemic treatment." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:38769 ! indazoles
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:65207 ! has role vascular endothelial growth factor receptor antagonist

[Term]
id: CHEBI:66916
name: alanine zwitterion
def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of alanine; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:16449 ! is tautomer of alanine

[Term]
id: CHEBI:66922
name: citrullinate
def: "An α-amino acid anion that is the conjugate base of citrulline, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:18211 ! is deprotonated form of citrulline

[Term]
id: CHEBI:66933
name: N-alkylglycine
def: "Any glycine derivative in which glycine is substituted at position 2 by an alkyl group." []
is_a: CHEBI:24373 ! glycine derivative
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid
relationship: RO:0018036 CHEBI:66884 ! is tautomer of N-alkylglycine zwitterion

[Term]
id: CHEBI:66934
name: cyanoamino acid anion
def: "An amino acid anion modified by the addition of a cyano group." []
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:60974 ! is deprotonated form of cyanoamino acid

[Term]
id: CHEBI:66956
name: antidyskinesia agent
def: "Any compound which can be used to treat or alleviate the symptoms of dyskinesia." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:66980
name: nootropic agent
def: "Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:66981
name: ophthalmology drug
def: "Any compound used for the treatment of eye conditions or eye diseases." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:66987
name: radiation protective agent
def: "Any compound that is able to protect normal cells from the damage caused by radiation therapy." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:66991
name: sympatholytic agent
def: "Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS)." []
is_a: CHEBI:37962 ! adrenergic agent

[Term]
id: CHEBI:66993
name: tocolytic agent
def: "Any compound used to suppress premature labour and immature birth by suppressing uterine contractions." []
is_a: CHEBI:50689 ! reproductive control drug

[Term]
id: CHEBI:67008
name: kynureninate
def: "An α-amino-acid anion obtained by the deprotonation of the carboxy group of kynurenine." []
is_a: CHEBI:33558 ! alpha-amino-acid anion
relationship: RO:0018033 CHEBI:28683 ! is deprotonated form of kynurenine

[Term]
id: CHEBI:67011
name: folates
def: "An <em>N</em>-acyl-<small>L</small>-α-amino acid anion obtained by deprotonation of any folic acid." []
is_a: CHEBI:176842 ! vitamin B9
is_a: CHEBI:59874 ! N-acyl-L-alpha-amino acid anion
relationship: RO:0018033 CHEBI:37445 ! is deprotonated form of folic acids

[Term]
id: CHEBI:67012
name: L-dopa(1-)
def: "A <small>L</small>-α-amino acid anion which is the conjugate base of <small>L</small>-dopa, obtained by deprotonation of the carboxy group: major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:59814 ! L-alpha-amino acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15765 ! is deprotonated form of L-dopa

[Term]
id: CHEBI:67013
name: methyl-branched fatty acid anion
def: "Any branched-chain fatty acid anion containing methyl branches only." []
is_a: CHEBI:58955 ! branched-chain fatty acid anion
relationship: RO:0018033 CHEBI:62499 ! is deprotonated form of methyl-branched fatty acid

[Term]
id: CHEBI:67016
name: tetrahydrofolate
def: "A folate obtained by deprotonation of any tetrahydrofolic acid." []
is_a: CHEBI:67011 ! folates
relationship: RO:0018033 CHEBI:26907 ! is deprotonated form of tetrahydrofolic acid

[Term]
id: CHEBI:67052
name: glyphosate(2-)
def: "An organophosphate oxoanion obtained by the deprotonation of the carboxy and one of the phosphate OH groups of glyphosate." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:133673 ! is deprotonated form of glyphosate(1-)

[Term]
id: CHEBI:67072
name: cannabinoid receptor agonist
def: "An agonist that binds to and activates cannabinoid receptors." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:67079
name: anti-inflammatory agent
def: "Any compound that has anti-inflammatory effects." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:67105
name: insect sterilant
def: "A chemosterilant intended to sterilize insects." []
is_a: CHEBI:23092 ! chemosterilant
is_a: CHEBI:24852 ! insecticide

[Term]
id: CHEBI:67114
name: ryanodine receptor agonist
def: "A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction." []
is_a: CHEBI:38809 ! ryanodine receptor modulator

[Term]
id: CHEBI:67142
name: nucleobase analogue
def: "A molecule that can substitute for a normal nucleobase in nucleic acids." []
is_a: CHEBI:33832 ! organic cyclic compound

[Term]
id: CHEBI:67144
name: 2-(morpholin-4-yl)ethanol
def: "A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group." []
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:50996 ! tertiary amino compound

[Term]
id: CHEBI:6717
name: mefenamic acid
def: "An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis." []
is_a: CHEBI:22495 ! aminobenzoic acid
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35544 ! has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:67189
name: EC 3.4.24.3 (microbial collagenase) inhibitor
def: "An EC 3.4.24.* (metalloendopeptidase) inhibitor which interferes with the action of microbial collagenase (EC 3.4.24.3, also formerly EC 3.4.4.19 and EC 3.4.99.5)." []
is_a: CHEBI:59107 ! EC 3.4.24.* (metalloendopeptidase) inhibitor

[Term]
id: CHEBI:67194
name: cannabinoid
def: "A diverse group of pharmacologically active secondary metabolite characteristic to <em>Cannabis</em> plant as well as produced naturally in the body by humans and animals. Cannabinoids contain oxygen as a part of the heterocyclic ring or in the form of various functional groups. They are subdivided on the basis of their origin." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0000087 CHEBI:67072 ! has role cannabinoid receptor agonist

[Term]
id: CHEBI:67195
name: gap junctional intercellular communication inhibitor
def: "An inhibitor that interferes with the process of gap junctional intercellular communication." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:67196
name: phytocannabinoid
def: "A class of cannabinoid which are C<small><sub>21</sub></small> terpenophenolic compounds isolated primarily from <em>Cannabis sativa</em>." []
is_a: CHEBI:67194 ! cannabinoid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:67197
name: endocannabinoid
def: "A class of cannabinoids present in mammalian biological fluids and tissues that activate cannabinoid receptors." []
is_a: CHEBI:18059 ! lipid
is_a: CHEBI:67194 ! cannabinoid
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:67198
name: retinoic acid receptor agonist
def: "An agonist that selectively binds to and activates a retinoic acid receptor." []
is_a: CHEBI:48705 ! agonist
is_a: CHEBI:90708 ! retinoic acid receptor modulator

[Term]
id: CHEBI:67199
name: AP-1 antagonist
def: "An antogonist that interferes with the action of activator protein 1 (AP-1)." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:67200
name: provitamin A
def: "A provitamin that can be converted into vitamin A by enzymes from animal tissues." []
is_a: CHEBI:50188 ! provitamin

[Term]
id: CHEBI:67208
name: double-stranded RNA
def: "A ribonucleic acid with two complementary strands, similar to the DNA found in all cells." []
is_a: CHEBI:33697 ! ribonucleic acid

[Term]
id: CHEBI:67239
name: EC 3.2.1.20 (alpha-glucosidase) inhibitor
def: "An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of α-glucosidase (EC 3.2.1.20)." []
is_a: CHEBI:52424 ! EC 3.2.1.* (glycosidase) inhibitor

[Term]
id: CHEBI:67265
name: beta-diketone
def: "A diketone in which the two keto groups are separated by a single carbon atom." []
is_a: CHEBI:46640 ! diketone

[Term]
id: CHEBI:67268
name: HIV-1 integrase inhibitor
def: "An inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells." []
is_a: CHEBI:64947 ! anti-HIV-1 agent
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:67271
name: MK-2206
def: "An organic heterotricyclic compound that is [1,2,4]triazolo[3,4-<em>f</em>][1,6]naphthyridin-3(2<em>H</em>)-one substituted by 4-(1-aminocyclobutyl)phenyl and phenyl groups at positions 8 and 9, respectively. It is an allosteric Akt inhibitor." []
is_a: CHEBI:156473 ! cyclobutanes
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:73539 ! naphthyridine derivative
relationship: RO:0000087 CHEBI:138880 ! has role autophagy inducer
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50925 ! has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:67273
name: monohydroxy-1,4-benzoquinones
def: "Any 1,4-benzoquinone carrying a single hydroxy substituent." []
is_a: CHEBI:132124 ! 1,4-benzoquinones
is_a: CHEBI:71648 ! hydroxybenzoquinone

[Term]
id: CHEBI:6736
name: melittin
def: "A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH<small><sub>2</sub></small> residues joined in sequence. It is the principal active component of bee venom." []
is_a: CHEBI:15722 ! peptidyl amide
is_a: CHEBI:15841 ! polypeptide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37700 ! has role EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:75767 ! has role animal metabolite
relationship: RO:0000087 CHEBI:78505 ! has role venom

[Term]
id: CHEBI:67410
name: p-hydroxybenzyl alcohol
def: "A member of the class of  benzyl alcohols that is  benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from <em>Arcangelisia gusanlung</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22743 ! benzyl alcohols
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:6775
name: mesalamine
def: "A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:25389 ! monohydroxybenzoic acid
is_a: CHEBI:33709 ! amino acid
is_a: CHEBI:33860 ! aromatic amine
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0018034 CHEBI:20551 ! is protonated form of mesalaminate(1-)
relationship: RO:0018038 CHEBI:16914 ! has functional parent salicylic acid

[Term]
id: CHEBI:6790
name: metalaxyl
def: "A racemate comprising equal amounts of (<i>R</i>)- and (<i>S</i>)-metalaxyl. A systemic fungicide, it is active against phytopathogens of the order <em>Peronosporales</em> and is used to conrtrol <em>Pythium</em> in a number of vegetable crops." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87013 ! acylamino acid fungicide
is_a: CHEBI:87015 ! anilide fungicide
relationship: BFO:0000051 CHEBI:60607 ! has part metalaxyl-M
relationship: BFO:0000051 CHEBI:82791 ! has part (S)-metalaxyl
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6791
name: metamitron
def: "A member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4<em>H</em>)-one substituted by an amino group at position 4, a methyl group at position 3 and a phenyl group at position 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39410 ! 1,2,4-triazines
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6798
name: metazachlor
def: "An organochlorine compound that is 2-chloroacetamide substituted by a 2,6-dimethylphenyl and a (1<em>H</em>-pyrazol-1-ylmethyl) group at the nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6801
name: metformin
def: "A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1." []
is_a: CHEBI:53662 ! biguanides
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35816 ! has role leprostatic drug
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:90688 ! is deprotonated form of metformin(1+)
relationship: RO:0018038 CHEBI:3095 ! has functional parent biguanide

[Term]
id: CHEBI:6802
name: metformin hydrochloride
def: "A hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride." []
is_a: CHEBI:36807 ! hydrochloride
is_a: CHEBI:53662 ! biguanides
relationship: BFO:0000051 CHEBI:90688 ! has part metformin(1+)
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6804
name: methacholine
def: "A quaternary ammonium ion in which the nitrogen is substituted with three methyl groups and a 2-acetoxypropyl group. Parasympathomimetic bronchoconstrictor drug used in clinical diagnosis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35267 ! quaternary ammonium ion
is_a: CHEBI:47622 ! acetate ester
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:38325 ! has role muscarinic agonist
relationship: RO:0000087 CHEBI:50141 ! has role bronchoconstrictor agent
relationship: RO:0000087 CHEBI:53000 ! has role epitope
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent

[Term]
id: CHEBI:6807
name: methadone
def: "A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:136003 ! has part levomethadone
relationship: BFO:0000051 CHEBI:167308 ! has part dextromethadone
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6809
name: methamphetamine
def: "A member of the class of amphetamines in which the amino group of (<i>S</i>)-amphetamine carries a methyl substituent." []
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:35338 ! amphetamines
relationship: RO:0000087 CHEBI:35471 ! has role psychotropic drug
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:132297 ! is deprotonated form of methamphetamine(1+)
relationship: RO:0018038 CHEBI:4469 ! has functional parent (S)-amphetamine

[Term]
id: CHEBI:6824
name: hexamethylenetetramine
def: "A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms." []
is_a: CHEBI:33640 ! polycyclic cage
is_a: CHEBI:38779 ! 1,3,5-triazinanes
is_a: CHEBI:39166 ! tetramine
is_a: CHEBI:39474 ! polyazaalkane
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug

[Term]
id: CHEBI:6835
name: methomyl
def: "A carbamate ester obtained by the formal condensation of  methylcarbamic acid with the hydroxy group of  1-(methylsulfanyl)acetaldoxime." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22327 ! aliphatic sulfide
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38534 ! has functional parent 1-(methylsulfanyl)acetaldoxime
relationship: RO:0018038 CHEBI:45379 ! has functional parent methylcarbamic acid

[Term]
id: CHEBI:6842
name: methoxychlor
is_a: CHEBI:25705 ! organochlorine insecticide
relationship: RO:0018038 CHEBI:39161 ! has functional parent 1,1,1-trichloro-2,2-diphenylethane

[Term]
id: CHEBI:6843
name: methoxyflurane
def: "An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:50909 ! has role nephrotoxic agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary

[Term]
id: CHEBI:68452
name: azole
def: "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." []
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38179 ! monocyclic heteroarene

[Term]
id: CHEBI:68472
name: pyrimidine deoxyribonucleoside
def: "A deoxyribonucleoside containing a pyrimidine base." []
is_a: CHEBI:23636 ! deoxyribonucleoside
is_a: CHEBI:26440 ! pyrimidine nucleoside

[Term]
id: CHEBI:68478
name: everolimus
def: "A macrocyclic lactone that is rapamycin in which the hydroxy group attached to the cyclohexyl moiety has been converted into the corresponding 2-hydroxyethyl ether. It is an immunosuppressant and antineoplastic agent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:145565 ! macrolide lactam
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:25698 ! ether
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:59770 ! cyclic acetal
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:68481 ! has role mTOR inhibitor
relationship: RO:0018038 CHEBI:9168 ! has functional parent sirolimus

[Term]
id: CHEBI:68481
name: mTOR inhibitor
def: "A protein kinase inhibitor of the <em>m</em>ammalian <em>t</em>arget <em>o</em>f <em>r</em>apamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer." []
is_a: CHEBI:37699 ! protein kinase inhibitor

[Term]
id: CHEBI:68487
name: strigolactone
def: "A family of sesquiterpene lactones with a common structure consisting of two lactone moieties (one a butenolide, the other a tricyclic γ-lactone) connected by an enol-ether bridge. Originally used to describe phytohormones with diverse signaling activities, biosynthesised from carotenoids, the term also includes synthetic analogues." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:37667 ! sesquiterpene lactone
is_a: CHEBI:50523 ! butenolide
relationship: RO:0000087 CHEBI:37848 ! has role plant hormone

[Term]
id: CHEBI:68489
name: alkyl,acyl-sn-glycero-3-phosphocholine
def: "A glycerophosphocholine that is <em>sn</em>-glycero-3-phosphocholine in which positions 1 and 2 are substituted by unspecified acyl and alkyl groups, and in which the positions of the acyl and alkyl groups are also unspecified." []
is_a: CHEBI:78189 ! alkylacylglycero-3-phosphocholine

[Term]
id: CHEBI:68494
name: apoptosis inhibitor
def: "Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:68495
name: apoptosis inducer
def: "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:68508
name: diethyl maleate
def: "A maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. A colourless liquid at room temperature (m.p. -10°C) with boiling point 220°C at 1 atm., it is commonly used as a dienophile for Diels-Alder-type cycloaddition reactions in organic synthesis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:35486 ! maleate ester
relationship: RO:0000087 CHEBI:68509 ! has role glutathione depleting agent

[Term]
id: CHEBI:68509
name: glutathione depleting agent
def: "A compound which causes a reduction in the levels of glutathione in cells." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:68542
name: EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor
def: "An EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitor that interferes with the action of dihydroorotate oxidase (fumarate), EC 1.3.98.1 (formerly EC 1.3.3.1)." []
is_a: CHEBI:76858 ! EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitor

[Term]
id: CHEBI:68543
name: pyrimidine synthesis inhibitor
def: "A pathway inhibitor that inhibits the synthesis of pyrimidine." []
is_a: CHEBI:76932 ! pathway inhibitor

[Term]
id: CHEBI:68563
name: P2Y12 receptor antagonist
def: "An antagonist at the P2Y<small><sub>12</sub></small> receptor" []
is_a: CHEBI:91079 ! purinergic receptor P2 antagonist

[Term]
id: CHEBI:68581
name: EC 3.4.21.6 (coagulation factor Xa) inhibitor
def: "An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of coagulation factor Xa (EC 3.4.21.6)." []
is_a: CHEBI:5924 ! EC 3.4.21.* (serine endopeptidase) inhibitor

[Term]
id: CHEBI:68612
name: EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor
def: "An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that specifically inhibits dipeptidyl peptidase-4 (EC 3.4.14.5)." []
is_a: CHEBI:76788 ! EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor

[Term]
id: CHEBI:68639
name: abiraterone acetate
def: "A sterol ester obtained by formal condensation of the 3-hydroxy group of abiraterone with the carboxy group of acetic acid. A prodrug that is converted <em>in vivo </em> into abiraterone. Used for treatment of metastatic castrate-resistant prostate cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35915 ! sterol ester
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:68640 ! has role EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor
relationship: RO:0018038 CHEBI:68642 ! has functional parent abiraterone

[Term]
id: CHEBI:68640
name: EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor
def: "An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of cytochrome P450 17-α-hydroxylase/C17,20-lyase (EC 1.14.99.9)." []
is_a: CHEBI:76840 ! EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

[Term]
id: CHEBI:68642
name: abiraterone
def: "A 3β-sterol that is androsta-5,16-dien-3β-ol substituted at position 17 by a 3-pyridyl group. Administered as the <em>O</em>-acetate, it is used for treatment of metastatic castrate-resistant prostate cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:1722 ! 3beta-hydroxy-Delta(5)-steroid
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35348 ! 3beta-sterol
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50113 ! has role androgen
relationship: RO:0000087 CHEBI:68640 ! has role EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor
relationship: RO:0018040 CHEBI:35509 ! has parent hydride androstane

[Term]
id: CHEBI:68657
name: zingerone
def: "A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:51867 ! methyl ketone
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0000087 CHEBI:48318 ! has role fragrance
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:66987 ! has role radiation protective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:6872
name: methylene blue
def: "An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties." []
is_a: CHEBI:36094 ! organic chloride salt
is_a: CHEBI:46899 ! benzothiazine
relationship: BFO:0000051 CHEBI:43830 ! has part 3,7-bis(dimethylamino)phenothiazin-5-ium
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35208 ! has role physical tracer
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:38623 ! has role EC 1.4.3.4 (monoamine oxidase) inhibitor
relationship: RO:0000087 CHEBI:50407 ! has role acid-base indicator
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0000087 CHEBI:77307 ! has role cardioprotective agent
relationship: RO:0000087 CHEBI:78678 ! has role EC 4.6.1.2 (guanylate cyclase) inhibitor

[Term]
id: CHEBI:68747
name: chaetocin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:6887
name: methylphenidate
def: "A racemate comprising equimolar amounts of the two <i>threo</i> isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:51857 ! has part methyl (S)-phenyl[(S)-piperidin-2-yl]acetate
relationship: BFO:0000051 CHEBI:51860 ! has part dexmethylphenidate
relationship: RO:0000087 CHEBI:35337 ! has role central nervous system stimulant
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:51039 ! has role dopamine uptake inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0018033 CHEBI:51856 ! is deprotonated form of methylphenidate(1+)

[Term]
id: CHEBI:6888
name: 6alpha-methylprednisolone
def: "The 6α-stereoisomer of  6-methylprednisolone." []
is_a: CHEBI:36699 ! corticosteroid hormone
is_a: CHEBI:50366 ! 6-methylprednisolone
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:37962 ! has role adrenergic agent
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:68889
name: hydroxytyrosol
def: "A member of the class of catechols that is benzene-1,2-diol substituted by a 2-hydroxyethyl group at position 4. Isolated from <em>Olea europaea</em>, it exhibits antioxidant and antineoplastic activities." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:33566 ! catechols
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018038 CHEBI:1879 ! has functional parent 2-(4-hydroxyphenyl)ethanol

[Term]
id: CHEBI:6902
name: metolachlor
def: "A racemate that consists of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-metolachlor." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83646 ! has part (R)-metolachlor
relationship: BFO:0000051 CHEBI:83647 ! has part (S)-metolachlor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6904
name: metoprolol
def: "A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a  4-(2-methoxyethyl)phenoxy group at position 1." []
is_a: CHEBI:35533 ! propanolamine
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6908
name: trichlorfon
def: "A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37592 ! organic phosphonate
is_a: CHEBI:37735 ! phosphonic ester
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35443 ! has role anthelminthic drug
relationship: RO:0000087 CHEBI:37733 ! has role EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: CHEBI:6909
name: metronidazole
def: "A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:35716 ! C-nitro compound
relationship: RO:0000087 CHEBI:132992 ! has role radiosensitizing agent
relationship: RO:0000087 CHEBI:171664 ! has role antiamoebic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50685 ! has role antitrichomonal drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug
relationship: RO:0018033 CHEBI:64682 ! is deprotonated form of metronidazole(1+)

[Term]
id: CHEBI:69136
name: latrunculin A
def: "A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge <em>Latrunculia magnifica</em> and from the Fiji Islands sponge <em>Cacospongia mycofijiensis</em>. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes." []
synonym: "(4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one" EXACT [PDBeChem]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25106 ! macrolide
is_a: CHEBI:46733 ! oxabicycloalkane
is_a: CHEBI:48891 ! thiazolidinone
is_a: CHEBI:59780 ! cyclic hemiketal
relationship: RO:0000087 CHEBI:27026 ! has role toxin
relationship: RO:0000087 CHEBI:70728 ! has role actin polymerisation inhibitor

[Term]
id: CHEBI:6925
name: microcystin-LR
def: "A microcystin consisting of <small>D</small>-alanyl, <small>L</small>-leucyl, (3<i>S</i>)-3-methyl-<small>D</small>-β-aspartyl,<small>L</small>-arginyl, 2<i>S</i>,3<i>S</i>,4<i>E</i>,6<i>E</i>,8<i>S</i>,9<i>S</i>)-3-amino-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyldecanoyl, <small>D</small>-γ-glutamyl, and 2,3-didehydro-<em>N</em>-methylalanyl residues joined into a 25-membered macrocycle. Produced by the cyanobacterium <em>Microcystis aeruginosa</em>, it is the most studied of the microcystins." []
is_a: CHEBI:48041 ! microcystin
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37153 ! has role EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:6931
name: midazolam
def: "An imidazobenzodiazepine that is 4<em>H</em>-imidazo[1,5-<em>a</em>][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively." []
is_a: CHEBI:142118 ! imidazobenzodiazepine
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:83575 ! monofluorobenzenes
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35717 ! has role sedative
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:38869 ! has role general anaesthetic
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:51371 ! has role muscle relaxant
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:91016 ! has role GABAA receptor agonist

[Term]
id: CHEBI:69441
name: p-methoxyphenol
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:51683 ! methoxybenzenes
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:69478
name: cannabidiol
def: "An cannabinoid that is cyclohexene which is substituted by a methyl group at position 1, a 2,6-dihydroxy-4-pentylphenyl group at position 3, and a prop-1-en-2-yl group at position 4." []
is_a: CHEBI:33572 ! resorcinols
is_a: CHEBI:67196 ! phytocannabinoid
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:69581
name: Paeonol
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:51683 ! methoxybenzenes
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:6964
name: molinate
def: "A member of the class of azepanes that is azepane in which the nitrogen is substituted by an (ethylsulfanyl)carbonyl group, -C(=O)SEt. A thiocarbamate herbicide not approved for use in the U.S. or European Union, it is used control grass weeds in rice paddies." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38128 ! monothiocarbamic ester
is_a: CHEBI:46986 ! azepanes
relationship: RO:0000087 CHEBI:145047 ! has role antispermatogenic agent
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:69797
name: catalpol
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:6980
name: monocrotaline
is_a: CHEBI:64948 ! pyrrolizidine alkaloid

[Term]
id: CHEBI:70436
name: platycodin D
is_a: CHEBI:61778 ! triterpenoid saponin

[Term]
id: CHEBI:70709
name: progesterone receptor agonist
def: "A hormone agonist that binds to and activates progesterone receptors." []
is_a: CHEBI:51060 ! hormone agonist

[Term]
id: CHEBI:7071
name: N,N-diethyl-m-toluamide
def: "A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of <em>m</em>-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:71692 ! has role insect repellent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:10589 ! has functional parent m-toluic acid

[Term]
id: CHEBI:70722
name: EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
def: "An EC 6.4.1.* (<em>C</em>‒<em>C</em> bond-forming ligase) inhibitor that interferes with the action of acetyl-CoA carboxylase (EC 6.4.1.2)." []
is_a: CHEBI:76824 ! EC 6.4.1.* (carboxylase) inhibitor

[Term]
id: CHEBI:70723
name: reversine
def: "A member of the class of purines that is 9<em>H</em>-purine in which the hydrogens at positions 2 and 6 are replaced by a [4-(morpholin-4-yl)phenyl]nitrilo group and a cyclohexylamino group, respectively." []
is_a: CHEBI:26401 ! purines
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:70724 ! has role cell dedifferentiation agent
relationship: RO:0000087 CHEBI:70725 ! has role adenosine A3 receptor antagonist
relationship: RO:0000087 CHEBI:70770 ! has role Aurora kinase inhibitor
relationship: RO:0018038 CHEBI:40235 ! has functional parent 9H-purine-2,6-diamine

[Term]
id: CHEBI:70724
name: cell dedifferentiation agent
def: "Any compound which induces a partially or terminally differentiated cell to revert to an earlier developmental stage." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:70725
name: adenosine A3 receptor antagonist
def: "An antagonist at the A<small><sub>3</sub></small> receptor." []
is_a: CHEBI:71232 ! adenosine receptor antagonist

[Term]
id: CHEBI:70726
name: hesperadin
def: "An oxindole that is indolin-2-one which is substituted at position 5 by an (ethylsulfonyl)nitrilo group and at position 2 by a methylidene group, which is itself substituted by a phenyl group and a [4-(piperidin-1-ylmethyl)phenyl]amino group. An Aurora B kinase inhibitor, it is used to inhibit chromosome alignment and segregation." []
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:38459 ! oxindoles
is_a: CHEBI:47989 ! enamine
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:70770 ! has role Aurora kinase inhibitor

[Term]
id: CHEBI:70727
name: topoisomerase inhibitor
def: "An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA)." []
is_a: CHEBI:76830 ! EC 5.99.1.* (miscellaneous isomerase) inhibitor

[Term]
id: CHEBI:70728
name: actin polymerisation inhibitor
def: "Any substance that inhibits the polymerisation of the protein actin." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:70734
name: lurasidone(1+)
def: "An organic cation that is the conjugate acid of lurasidone." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:70735 ! is protonated form of lurasidone

[Term]
id: CHEBI:70735
name: lurasidone
def: "An <em>N</em>-arylpiperazine that is (3a<i>R</i>,4<i>S</i>,7<i>R</i>,7a<i>S</i>)-2-{[(1<i>R</i>,2<i>R</i>)-2-(piperazin-1-ylmethyl)cyclohexyl]methyl}hexahydro-1<em>H</em>-4,7-methanoisoindole-1,3(2<em>H</em>)-dione in which position N4 of the piperazine ring is substituted by a 1,2-benzothiazol-3-yl group. Lurasidone is used (generally as the hydrochloride salt) as an atypical antipsychotic for the treatment of schizophrenia." []
is_a: CHEBI:35356 ! dicarboximide
is_a: CHEBI:35990 ! bridged compound
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:55505 ! 1,2-benzisothiazole
relationship: RO:0000087 CHEBI:37887 ! has role adrenergic antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic
relationship: RO:0018033 CHEBI:70734 ! is deprotonated form of lurasidone(1+)
relationship: RO:0018038 CHEBI:16072 ! has functional parent maleimide

[Term]
id: CHEBI:70744
name: Gly-Pro
def: "A dipeptide consisting of <small>L</small>-proline having a glycyl residue attached to its α-amino group." []
is_a: CHEBI:46761 ! dipeptide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018036 CHEBI:73779 ! is tautomer of Gly-Pro zwitterion
relationship: RO:0018038 CHEBI:15428 ! has functional parent glycine
relationship: RO:0018038 CHEBI:17203 ! has functional parent L-proline

[Term]
id: CHEBI:70746
name: dabigatran etexilate
def: "An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{<em>N</em>'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1<em>H</em>-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl <em>N</em>-pyridin-2-yl-β-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:22823 ! beta-alanine derivative
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:35359 ! carboxamidine
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:65232 ! has role EC 3.4.21.5 (thrombin) inhibitor
relationship: RO:0018033 CHEBI:70751 ! is deprotonated form of dabigatran etexilate(1+)
relationship: RO:0018038 CHEBI:70752 ! has functional parent dabigatran

[Term]
id: CHEBI:70751
name: dabigatran etexilate(1+)
def: "An organic cation that is the conjugate acid of dabigatran etexilate." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:70746 ! is protonated form of dabigatran etexilate

[Term]
id: CHEBI:70752
name: dabigatran
def: "An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1<em>H</em>-benzimidazole-5-carboxylic acid with the secondary amoino group of <em>N</em>-pyridin-2-yl-β-alanine. The active metabolite of the prodrug  dabigatran etexilate, it acts as an anticoagulant which is used for the prevention of stroke and systemic embolism." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:22823 ! beta-alanine derivative
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35359 ! carboxamidine
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:65232 ! has role EC 3.4.21.5 (thrombin) inhibitor
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:77020 ! has role EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor

[Term]
id: CHEBI:70770
name: Aurora kinase inhibitor
def: "Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation)." []
is_a: CHEBI:37699 ! protein kinase inhibitor

[Term]
id: CHEBI:70773
name: capsazepine
def: "A benzazepine that is 2,3,4,5-tetrahydro-1<em>H</em>-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(<em>p</em>-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33566 ! catechols
is_a: CHEBI:35676 ! benzazepine
is_a: CHEBI:51276 ! thioureas
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:70774 ! has role capsaicin receptor antagonist

[Term]
id: CHEBI:70774
name: capsaicin receptor antagonist
def: "Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:70778
name: GW 7647
def: "A monocarboxylic acid that is 2-(phenylsulfanyl)isobutyric acid in which the phenyl group is substituted at the <em>para</em>- position by a 3-aza-7-cyclohexylhept-1-yl group in which the nitrogen is acylated by a (cyclohexylamino)carbonyl group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:47857 ! ureas
relationship: RO:0000087 CHEBI:70782 ! has role PPARalpha agonist

[Term]
id: CHEBI:70781
name: PPAR modulator
def: "Any compound which acts on the peroxisome proliferator-activated receptor." []
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:70782
name: PPARalpha agonist
def: "A PPAR modulator which activates the peroxisome proliferator-activated receptor-α." []
is_a: CHEBI:48705 ! agonist
is_a: CHEBI:70781 ! PPAR modulator

[Term]
id: CHEBI:70817
name: EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor
def: "An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor) inhibitor that interferes with the action of glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)." []
is_a: CHEBI:76852 ! EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:70868
name: antileishmanial agent
def: "An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus <em>Leishmania</em>." []
is_a: CHEBI:35820 ! antiprotozoal drug

[Term]
id: CHEBI:70977
name: alkane-alpha,omega-diammonium(2+)
def: "An organic cation obtained by protonation of the amino groups of any alkane-α,ω-diamine; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:35411 ! is protonated form of alkane-alpha,omega-diamine

[Term]
id: CHEBI:70982
name: reactive oxygen species generator
def: "Any entity used to generate reactive oxygen species." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:70994
name: hexacyclic triterpenoid
def: "A triterpenoid that consists of a hexacyclic ring system." []
is_a: CHEBI:36615 ! triterpenoid
is_a: CHEBI:51958 ! organic polycyclic compound

[Term]
id: CHEBI:70998
name: G-protein-coupled receptor agonist
def: "An agonist that binds to and activates G-protein-coupled receptors" []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:71019
name: omacetaxine mepesuccinate
def: "A cephalotaxine-derived alkaloid ester obtained from <em>Cephalotaxus harringtonia</em>; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:38481 ! alkaloid ester
is_a: CHEBI:38523 ! benzazepine alkaloid
is_a: CHEBI:47985 ! enol ether
is_a: CHEBI:59770 ! cyclic acetal
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0018038 CHEBI:3540 ! has functional parent cephalotaxine

[Term]
id: CHEBI:71181
name: Sir2 inhibitor
def: "An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2." []
is_a: CHEBI:61115 ! EC 3.5.1.98 (histone deacetylase) inhibitor

[Term]
id: CHEBI:71200
name: tofacitinib
def: "A pyrrolopyrimidine that is pyrrolo[2,3-<em>d</em>]pyrimidine substituted at position 4 by an <em>N</em>-methyl,<em>N</em>-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:38670 ! pyrrolopyrimidine
is_a: CHEBI:48591 ! N-acylpiperidine
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:76617 ! has role EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

[Term]
id: CHEBI:71212
name: prohormone
def: "Any intra-glandular substance that acts as a precursor of a hormone, usually having minimal hormonal effect itself. Prohormones generally help in amplifying the effect of existing hormones." []
is_a: CHEBI:24432 ! biological role

[Term]
id: CHEBI:71217
name: pazopanib hydrochloride
def: "A hydrochloride salt prepared from equimolar amounts of pazopanib and hydrochloric acid. Used for treatment of kidney cancer." []
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:36807 ! hydrochloride
is_a: CHEBI:50996 ! tertiary amino compound
relationship: BFO:0000051 CHEBI:71218 ! has part pazopanib(1+)
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:50926 ! has role angiogenesis modulating agent
relationship: RO:0000087 CHEBI:65207 ! has role vascular endothelial growth factor receptor antagonist

[Term]
id: CHEBI:71218
name: pazopanib(1+)
def: "An organic cation that is the conjugate acid of pazopanib." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:71219 ! is protonated form of pazopanib

[Term]
id: CHEBI:71219
name: pazopanib
def: "A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer." []
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:38769 ! indazoles
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50926 ! has role angiogenesis modulating agent
relationship: RO:0000087 CHEBI:65207 ! has role vascular endothelial growth factor receptor antagonist
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0018033 CHEBI:71218 ! is deprotonated form of pazopanib(1+)

[Term]
id: CHEBI:71230
name: dihydrochalcones
def: "Any ketone that is 1,3-diphenylpropanone and its derivatives obtained by substitution." []
is_a: CHEBI:72544 ! flavonoids
is_a: CHEBI:76224 ! aromatic ketone

[Term]
id: CHEBI:71232
name: adenosine receptor antagonist
def: "An antagonist at any adenosine receptor." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:71240
name: sodium diphosphate
def: "An inorganic sodium salt comprised of a diphosphate(4−) anion and four sodium(1+) cations. More commonly known as tetrasodium pyrophosphate, it finds much use in the food industry as an emulsifier and in dental hygiene as a calcium-chelating salt." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38702 ! inorganic sodium salt
is_a: CHEBI:62889 ! organic diphosphate
relationship: BFO:0000051 CHEBI:18361 ! has part diphosphate(4-)
relationship: RO:0000087 CHEBI:38161 ! has role chelator
relationship: RO:0000087 CHEBI:63047 ! has role food emulsifier
relationship: RO:0000087 CHEBI:77970 ! has role food thickening agent

[Term]
id: CHEBI:71300
name: EC 2.* (transferase) inhibitor
def: "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" []
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:71337
name: minocycline(1-)
def: "An organic anion that is the conjugate base of minocycline, obtained by deprotonation of the two enolic hydroxy groups and protonation of the non-aromatic tertiary amino group." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:50694 ! is deprotonated form of minocycline
relationship: RO:0018033 CHEBI:77906 ! is deprotonated form of minocycline zwitterion

[Term]
id: CHEBI:71365
name: rifampicin zwitterion
def: "A zwitterion obtained by transfer of a proton from the 5-hydroxy group to the tertiary amino group of rifampicin; major species at pH 7.3." []
is_a: CHEBI:27369 ! zwitterion
relationship: RO:0018036 CHEBI:28077 ! is tautomer of rifampicin

[Term]
id: CHEBI:71392
name: tetracycline(1-)
def: "An organic anion that is the conjugate base of tetracycline zwitterion obtained by deprotonation of the two enolic hydroxy groups and protonation of the tertiary amino group." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:77932 ! is deprotonated form of tetracycline zwitterion

[Term]
id: CHEBI:71406
name: (R)-adrenaline(1+)
def: "An organic cation that is the conjugate acid of (<i>R</i>)-adrenaline, obtained by protonation of the amino group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:28918 ! is protonated form of (R)-adrenaline

[Term]
id: CHEBI:71415
name: nitrofurantoin
def: "An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA." []
is_a: CHEBI:24628 ! imidazolidine-2,4-dione
is_a: CHEBI:87230 ! nitrofuran antibiotic
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0018038 CHEBI:28306 ! has functional parent semicarbazide

[Term]
id: CHEBI:71418
name: triamcinolone acetonide
def: "A synthetic glucocorticoid that is the 16,17-acetonide of triamcinolone. Used to treat various skin infections." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:50830 ! fluorinated steroid
is_a: CHEBI:59779 ! cyclic ketal
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0018038 CHEBI:9667 ! has functional parent triamcinolone
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:71449
name: hexadec-9-enoate
def: "A long-chain unsaturated fatty acid anion that is the conjugate base of hexadec-9-enoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:78095 ! hexadecenoate
relationship: RO:0018033 CHEBI:72004 ! is deprotonated form of hexadec-9-enoic acid

[Term]
id: CHEBI:71476
name: EC 2.3.1.85 (fatty acid synthase) inhibitor
def: "An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis." []
is_a: CHEBI:76878 ! EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor

[Term]
id: CHEBI:71543
name: rotenoid
def: "Members of the class of tetrahydrochromenochromene that consists of a <i>cis</i>-fused tetrahydrochromeno[3,4-<em>b</em>]chromene skeleton and its substituted derivatives. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds." []
is_a: CHEBI:72544 ! flavonoids
is_a: CHEBI:72579 ! tetrahydrochromenochromene

[Term]
id: CHEBI:71554
name: PPARgamma agonist
def: "A PPAR modulator which activates the peroxisome proliferator-activated receptor-γ." []
is_a: CHEBI:48705 ! agonist
is_a: CHEBI:70781 ! PPAR modulator

[Term]
id: CHEBI:71648
name: hydroxybenzoquinone
def: "Benzoquinones with at least one hydroxy substituent." []
is_a: CHEBI:132130 ! hydroxyquinone
is_a: CHEBI:22729 ! benzoquinones
is_a: CHEBI:33823 ! enol

[Term]
id: CHEBI:71666
name: gamma-amino acid anion
def: "An amino-acid anion in which the amino group is situated γ- to the carboxylate group." []
is_a: CHEBI:37022 ! amino-acid anion
relationship: RO:0018033 CHEBI:33707 ! is deprotonated form of gamma-amino acid

[Term]
id: CHEBI:71692
name: insect repellent
def: "An insecticide that acts as a repellent to insects." []
is_a: CHEBI:24852 ! insecticide

[Term]
id: CHEBI:71942
name: EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor
def: "An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that blocks the action of 3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35)." []
is_a: CHEBI:50218 ! EC 3.1.4.* (phosphoric diester hydrolase) inhibitor

[Term]
id: CHEBI:71944
name: aldehydic acid anion
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of an aldehydic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:26643 ! is deprotonated form of aldehydic acid

[Term]
id: CHEBI:71971
name: neoflavonoid
def: "Any 1-benzopyran with an aryl substituent at position 4. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds." []
is_a: CHEBI:26004 ! phenylpropanoid
is_a: CHEBI:38443 ! 1-benzopyran
is_a: CHEBI:72544 ! flavonoids

[Term]
id: CHEBI:71989
name: ortho ester
def: "Any organooxygen compound that has the general formula RC(OR<small><sup>1</small></sup>)(OR<small><sup>2</small></sup>)(OR<small><sup>3</small></sup>), where R<small><sup>1</small></sup>, R<small><sup>2</small></sup>, R<small><sup>3</small></sup> ≠ H." []
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:71992
name: fisetin(1-)
def: "A flavonoid oxoanion that is the conjugate base of fisetin." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:42567 ! is deprotonated form of fisetin

[Term]
id: CHEBI:72004
name: hexadec-9-enoic acid
def: "A hexadecenoic acid in which the double bond is located at position 9." []
is_a: CHEBI:24548 ! hexadecenoic acid
relationship: RO:0018034 CHEBI:71449 ! is protonated form of hexadec-9-enoate

[Term]
id: CHEBI:72010
name: hydroxyflavan
def: "A member of the class of flavans in which one or more ring hydrogens are replaced by hydroxy groups." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:38672 ! flavans

[Term]
id: CHEBI:7203
name: N-acetylhexosamine
is_a: CHEBI:21656 ! N-acyl-hexosamine

[Term]
id: CHEBI:72292
name: bedaquiline
def: "A quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:26776 ! stilbenoid
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37141 ! organobromine compound
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:20854 ! has role ATP synthase inhibitor
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35816 ! has role leprostatic drug
relationship: RO:0018033 CHEBI:72706 ! is deprotonated form of bedaquiline(2+)

[Term]
id: CHEBI:72296
name: apixaban
def: "A pyrazolopyridine that is 7-oxo-4,5,6,7-tetrahydro-1<em>H</em>-pyrazolo[3,4-<em>c</em>]pyridine-3-carboxamide substituted at position 1 by a 4-methoxyphenyl group and at position 6 by a 4-(2-oxopiperidin-1-yl)phenyl group. It is used for the prevention and treatment of thromboembolic diseases." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24995 ! lactam
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:46699 ! pyrazolopyridine
is_a: CHEBI:48589 ! piperidones
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:68581 ! has role EC 3.4.21.6 (coagulation factor Xa) inhibitor
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:72316
name: virulence factor
def: "Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host." []
is_a: CHEBI:27026 ! toxin

[Term]
id: CHEBI:72317
name: cabozantinib
def: "A dicarboxylic acid diamide that is <em>N</em>-phenyl-<em>N</em>'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:35779 ! dicarboxylic acid diamide
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor

[Term]
id: CHEBI:72449
name: malachite green
def: "An organic chloride salt that is the monochloride salt of malachite green cation. Used as a green-coloured dye, as a counter-stain in histology, and for its anti-fungal properties in aquaculture." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36094 ! organic chloride salt
relationship: BFO:0000051 CHEBI:44107 ! has part malachite green cation
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:72457
name: 2-fluoroadenine
def: "An organofluorine compound that is adenine in which the hydrogen at position 2 (the carbon between the two nitrogens of the pyrimidine ring) is replaced by a fluorine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26401 ! purines
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:72470
name: provitamin B1
def: "A provitamin that can be converted into vitamin B<small><sub>1</sub></small> by enzymes from animal tissues." []
is_a: CHEBI:50188 ! provitamin

[Term]
id: CHEBI:72542
name: 4-[4-(dimethylamino)styryl]-N-methylpyridinium
def: "A pyridinium cation obtained by methylation at position 1 of 4-(4-dimethylaminostyryl)pyridine" []
is_a: CHEBI:50334 ! pyridinium ion

[Term]
id: CHEBI:72544
name: flavonoids
def: "Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C<small><sub>15</sub></small> or C<small><sub>16</sub></small> skeleton, or such a structure which is condensed with a C<small><sub>6</sub></small>-C<small><sub>3</sub></small> lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them." []
is_a: CHEBI:25806 ! oxygen molecular entity
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:72564
name: temozolomide
def: "An imidazotetrazine that is 3,4-dihydroimidazo[5,1-<em>d</em>][1,2,3,5]tetrazine which is substituted at positions 3, 4, and 8 by methyl, oxo, and carboxamide groups, respectively. A prodrug for MTIC (5-(3-methyltriaz-1-en-1-yl)-1<em>H</em>-imidazole-4-carboxamide, formed by spontaneous hydrolysis of temozolomide in the body), it is used as an oral alkylating agent for the treatment of newly diagnosed malignant  glioblastoma multiforme (concomitantly with radiotherapy) and malignant melanoma." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:72565 ! imidazotetrazine
is_a: CHEBI:72573 ! triazene derivative
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug

[Term]
id: CHEBI:72565
name: imidazotetrazine
def: "Any organic heterobicyclic compound containing ortho-fused imidazole and tetrazine rings." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:72571
name: pro-angiogenic agent
def: "Any compound that promotes the growth of new blood vessels from pre-existing vessels." []
is_a: CHEBI:50926 ! angiogenesis modulating agent

[Term]
id: CHEBI:72572
name: isoflavans
def: "Any isoflavonoid with a 3,4-dihydro-3-aryl-2<em>H</em>-1-benzopyran skeleton and its substituted derivatives." []
is_a: CHEBI:50753 ! isoflavonoid

[Term]
id: CHEBI:72573
name: triazene derivative
def: "A nitrogen molecular entity resulting from the formal substitution of one or more of the hydrogens of triazene." []
is_a: CHEBI:51143 ! nitrogen molecular entity
relationship: RO:0018040 CHEBI:35468 ! has parent hydride triazene

[Term]
id: CHEBI:72579
name: tetrahydrochromenochromene
def: "Any chromenochromene resulting from the formal <i>cis</i>-fusion of two dihydro chromene rings, together with their substituted derivatives." []
is_a: CHEBI:133135 ! chromenochromene

[Term]
id: CHEBI:72581
name: rotenones
def: "Members of the class of rotenoid which consists of a 6a,12a-dihydrochromeno[3,4-<em>b</em>]chromen-12(6<em>H</em>)-one skeleton and its substituted products." []
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:71543 ! rotenoid

[Term]
id: CHEBI:72588
name: semisynthetic derivative
def: "Any organic molecular entity derived from a natural product by partial chemical synthesis." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:72596
name: papulacandin
def: "Any of the carbohydrate-containing antibiotic compounds obtained from the deuteromycetous fungus <em>Papularia sphaerosperma</em> and generally consisting of <em>o</em>-orsellinic acid linked via a spirocyclic structure to a lactose moiety with two different side-chains: a shorter fatty-acid chain at the <em>O</em>-(6') position and a longer side-chain at the <em>O</em>-(3) position of the glucose moiety. Papulacandin D, the simplest member of the papulacandin family, lacks the <em>O</em>-(6'-acyl-β-galactoside) at the <em>O</em>-(4) position of the glucose residue. The papulacandins show potent antifungal activity against <em>Candida albicans</em>, <em>Geotrichum lactis</em>, <em>Saccharomyces cerevisiae</em>, and <em>Pneumocytis carinii</em>, but are inactive against filamentous fungi, bacteria, and protazoa." []
is_a: CHEBI:20857 ! C-glycosyl compound
is_a: CHEBI:23007 ! carbohydrate-containing antibiotic
is_a: CHEBI:35748 ! fatty acid ester
is_a: CHEBI:38831 ! 2-benzofurans
is_a: CHEBI:72600 ! spiroketal
relationship: RO:0018038 CHEBI:32807 ! has functional parent o-orsellinic acid

[Term]
id: CHEBI:72600
name: spiroketal
def: "A cyclic ketal in which the ketal carbon is the only common atom of two rings." []
is_a: CHEBI:37948 ! oxaspiro compound
is_a: CHEBI:59779 ! cyclic ketal

[Term]
id: CHEBI:72695
name: organic molecule
def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." []
is_a: CHEBI:25367 ! molecule
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:72704
name: chromenyliums
def: "Any organic cation that consists of a chromenylium skeleton and its substituted derivatives thereof." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35573 ! organic mancude parent
relationship: RO:0018040 CHEBI:35601 ! has parent hydride 2H-chromene
relationship: RO:0018040 CHEBI:35603 ! has parent hydride 4H-chromene

[Term]
id: CHEBI:72706
name: bedaquiline(2+)
def: "An ammonium ion resulting from the protonation of both nitrogen atoms of bedaquiline." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:72292 ! is protonated form of bedaquiline

[Term]
id: CHEBI:72709
name: flavonolignan
def: "Any lignan condensed with a 2-aryl-1-benzopyran skeleton and its substituted derivatives." []
is_a: CHEBI:25036 ! lignan
is_a: CHEBI:38443 ! 1-benzopyran
is_a: CHEBI:72544 ! flavonoids

[Term]
id: CHEBI:72720
name: flavonoid oligomer
def: "A phenylpropanoid obtained by the coupling of two or more units of aryl-substituted benzopyran units and their substituted derivatives." []
is_a: CHEBI:26004 ! phenylpropanoid
is_a: CHEBI:38443 ! 1-benzopyran
is_a: CHEBI:72544 ! flavonoids

[Term]
id: CHEBI:72730
name: flavanone glycoside
def: "A member of the class of flavanones having one or more glycosyl residues attached at unspecified positions." []
is_a: CHEBI:24400 ! glycoside
is_a: CHEBI:28863 ! flavanones

[Term]
id: CHEBI:72768
name: aryl hydrocarbon receptor agonist
def: "An agonist that binds to and activates aryl hydrocarbon receptors (AhRs)." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:72773
name: carotogenesis inhibitor
def: "Any inhibitor of the biosynthesis of carotenoids." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:72774
name: EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor
def: "An EC 1.3.99.* (oxidoreductase acting on donor CH-CH group with other acceptors) inhibitor that interferes with the action of phytoene desaturase (ζ-carotene-forming), EC 1.3.99.29, an enzyme of carotenoid biosynthesis that converts phytoene into ζ-carotene (zeta-carotene) via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene." []
is_a: CHEBI:76859 ! EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitor

[Term]
id: CHEBI:72813
name: exopolysaccharide
def: "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." []
is_a: CHEBI:33694 ! biomacromolecule

[Term]
id: CHEBI:72818
name: 5-fluoroindole
def: "An organofluorine compound that is the 5-fluoro derivative of indole." []
is_a: CHEBI:131960 ! fluoroindole

[Term]
id: CHEBI:72854
name: EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor
def: "An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the action of indoleamine 2,3-dioxygenase (EC 1.13.11.52)." []
is_a: CHEBI:76837 ! EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor

[Term]
id: CHEBI:73044
name: lumiracoxib
def: "An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33709 ! amino acid
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:50629 ! has role cyclooxygenase 2 inhibitor

[Term]
id: CHEBI:73080
name: hemiaminal
def: "Any organic amino compound that has an amino group and a hydroxy group attached to the same carbon atom. Hemiaminals are intermediates in the formation of imines by addition of an amine to an aldehyde or ketone; those derived from primary amines are particularly unstable." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:73155
name: trienoic fatty acid
def: "Any polyunsaturated fatty acid that contains three double bonds." []
is_a: CHEBI:26208 ! polyunsaturated fatty acid
is_a: CHEBI:53339 ! olefinic fatty acid

[Term]
id: CHEBI:73159
name: pyrabactin
def: "A sulfonamide obtained by formal condensation of the sulfo group of 4-bromonaphthalene-1-sulfonic acid with the exocyclic amino group of 2-pyridylmethylamine. Mimics the action of the abscisic acid, a phytohormone." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:37141 ! organobromine compound
relationship: RO:0000087 CHEBI:24621 ! has role hormone
relationship: RO:0000087 CHEBI:26155 ! has role plant growth regulator
relationship: RO:0000087 CHEBI:73191 ! has role abscisic acid receptor agonist

[Term]
id: CHEBI:73163
name: oryzalin
def: "A sulfonamide that is benzenesulfonamide substituted at positions 3 and 5 by nitro groups and at position 4 by a dipropylamino group." []
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:64911 ! has role antimitotic

[Term]
id: CHEBI:73173
name: 2,4-DB
def: "A monocarboxylic acid that is butyric acid in which one of the hydrogens at position 4 is replaced by a 2,4-dichlorophenoxy group. A selective post-emergence herbicide." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0018034 CHEBI:143277 ! is protonated form of 4-(2,4-dichlorophenoxy)butanoate

[Term]
id: CHEBI:73178
name: acibenzolar-S-methyl
def: "A benzothiadiazole that is the <em>S</em>-methyl thioester derivative of acibenzolar. A profungicide (by hydrolysis of the thioester group to give the corresponding carboxylic acid), it is used as a fungicide and plant activator on a variety of crops, including cotton, chili peppers, lettuce, onions, spinach, tobacco, and tomatoes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48864 ! benzothiadiazole
is_a: CHEBI:51277 ! thioester
relationship: RO:0000087 CHEBI:136645 ! has role profungicide
relationship: RO:0000087 CHEBI:73182 ! has role plant activator
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:73185 ! has functional parent acibenzolar

[Term]
id: CHEBI:73181
name: EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor
def: "An  EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of <small>L</small>-ascorbate peroxidase (EC 1.11.1.11)." []
is_a: CHEBI:75381 ! EC 1.11.1.* (peroxidases) inhibitor

[Term]
id: CHEBI:73182
name: plant activator
def: "Any compound that protects plants by activating their defence mechanisms." []
is_a: CHEBI:33286 ! agrochemical

[Term]
id: CHEBI:73185
name: acibenzolar
def: "A benzothiadiazole that is 1,2,3-benzothiadiazole in which the hydrogen at position 7 is replaced by a sulfanylcarbonyl group. It is used (particularly as its <em>S</em>-methyl thioester) as a fungicide and plant activator." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48864 ! benzothiadiazole
relationship: RO:0000087 CHEBI:73182 ! has role plant activator
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:73191
name: abscisic acid receptor agonist
def: "An agonist that binds to and activates abscisic acid receptors." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:73192
name: EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor
def: "An EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitor that interferes with the action of protoporphyrinogen oxidase (EC 1.3.3.4)." []
is_a: CHEBI:76860 ! EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor

[Term]
id: CHEBI:73193
name: gibberellin biosynthesis inhibitor
def: "Any compound that inhibits one or more steps in the pathway leading to the synthesis of gibberellins." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:73214
name: EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor
def: "An  EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H<small><sup>+</small></sup>-transporting two-sector ATPase inhibitor (EC 3.6.3.14)." []
is_a: CHEBI:76895 ! EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor

[Term]
id: CHEBI:73216
name: EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor
def: "Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*)." []
is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor

[Term]
id: CHEBI:73240
name: NF-kappaB inhibitor
def: "An inhibitor of NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:73263
name: cyclooxygenase 3 inhibitor
def: "A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 3." []
is_a: CHEBI:35544 ! EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor

[Term]
id: CHEBI:73267
name: oxidative phosphorylation inhibitor
def: "Any compound that inhibits oxidative phosphorylation." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:73273
name: sodium-glucose transport protein subtype 2 inhibitor
def: "Any inhibitor that interferes with the action of sodium-glucose transport protein subtype 2." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:73311
name: adenosine receptor agonist
def: "An agonist at any adenosine receptor." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:73333
name: scabicide
def: "An acaricide that kills mites of the genus <em>Sarcoptes</em>." []
is_a: CHEBI:22153 ! acaricide

[Term]
id: CHEBI:73335
name: ultraviolet filter
def: "A photochemical role realized in the absorption of ultraviolet light, for example to protect skin cells from damage." []
is_a: CHEBI:52215 ! photochemical role

[Term]
id: CHEBI:73336
name: vulnerary
def: "A drug used in treating and healing of wounds." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:73359
name: alpha-CH2-containing aldehyde
def: "An aldehyde of general formula R-CH<small><sub>2</sub></small>-CH=O in which the aldehydic C=O function is attached to a CH<small><sub>2</sub></small> group at the α-position." []
is_a: CHEBI:17478 ! aldehyde

[Term]
id: CHEBI:73360
name: EC 3.4.11.18 (methionyl aminopeptidase) inhibitor
def: "Any EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of methionyl aminopeptidase (EC 3.4.11.18)." []
is_a: CHEBI:76787 ! EC 3.4.11.* (aminopeptidase) inhibitor

[Term]
id: CHEBI:73361
name: methionine aminopeptidase 2 inhibitor
def: "Any methionyl aminopeptidase inhibitor that inhibits the action of methionyl aminopeptidase 2." []
is_a: CHEBI:73360 ! EC 3.4.11.18 (methionyl aminopeptidase) inhibitor

[Term]
id: CHEBI:73398
name: indole skeleton
def: "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." []
is_a: CHEBI:73541 ! organic heterobicyclic ring

[Term]
id: CHEBI:73413
name: cannabinoid receptor antagonist
def: "An antagonist that binds to and deactivates cannabinoid receptors." []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:73416
name: CB1 receptor antagonist
def: "An antagonist that binds to and deactivates type 1 cannabinoid receptors." []
is_a: CHEBI:73413 ! cannabinoid receptor antagonist

[Term]
id: CHEBI:73474
name: acetylenic compound
def: "Any organic molecule containing a C≡C bond." []
is_a: CHEBI:72695 ! organic molecule

[Term]
id: CHEBI:73477
name: terminal acetylenic compound
def: "An acetylenic compound which a carbon of the C≡C moiety is attached to a hydrogen atom." []
is_a: CHEBI:73474 ! acetylenic compound

[Term]
id: CHEBI:73539
name: naphthyridine derivative
def: "Any organonitrogen heterocyclic compound that is a derivative of a naphthyridine." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
relationship: RO:0018040 CHEBI:36624 ! has parent hydride naphthyridine

[Term]
id: CHEBI:73541
name: organic heterobicyclic ring
def: "A bicyclic organic group that contains both carbon and hetero atoms." []
is_a: CHEBI:52845 ! cyclic organic group

[Term]
id: CHEBI:73558
name: D3 vitamins
def: "A vitamin D that is calciol or its hydroxylated metabolites calcidiol and calcitriol. Calciol (also known as vitamin D<small><sub>3</sub></small>) acts as a hormone precursor, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D<small><sub>3</sub></small>), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D<small><sub>3</sub></small>), the active hormone." []
is_a: CHEBI:27300 ! vitamin D

[Term]
id: CHEBI:73678
name: tobramycin(5+)
def: "An organic cation obtained by protonation of the five amino groups of tobramycin." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:28864 ! is protonated form of tobramycin

[Term]
id: CHEBI:73690
name: erythrose 4-phosphate/phosphoenolpyruvate family amino acid
def: "An <small>L</small>-α-amino acid which is biosynthesised from erythrose 4-phosphate and phosphoenolpyruvate (i.e. phenylalanine, tyrosine, and tryptophan). A closed class." []
is_a: CHEBI:15705 ! L-alpha-amino acid
is_a: CHEBI:83813 ! proteinogenic amino acid

[Term]
id: CHEBI:73693
name: ketone body
def: "A carbonyl compound produced as a water-soluble byproduct when fatty acids are broken down for energy in the liver. There are three endogenous ketone bodies: acetone, acetoacetic acid, and (<i>R</i>)-3-hydroxybutyric acid; others may be produced as a result of the metabolism of synthetic triglycerides." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36586 ! carbonyl compound
is_a: CHEBI:61697 ! fatty acid derivative
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent

[Term]
id: CHEBI:73716
name: diazomethane
def: "The simplest diazo compound, in which a diazo group is attached to a methylene group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39444 ! diazo compound
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:64909 ! has role poison

[Term]
id: CHEBI:73726
name: GW 501516
def: "An aromatic ether that is phenoxyacetic acid in which the phenyl group is substituted at position 2 by a methyl group and at position 4 by a (1,3-thiazol-5-ylmethyl)sulfanediyl group, and in which the 1,3-thiazolyl group is substituted at positions 2 and 4 by <em>p</em>-trifluoromethylphenyl and methyl groups, respectively." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38418 ! 1,3-thiazoles
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:73730 ! has role PPARbeta/delta agonist

[Term]
id: CHEBI:73730
name: PPARbeta/delta agonist
def: "A PPAR modulator which activates the peroxisome proliferator-activated receptor-β/δ." []
is_a: CHEBI:48705 ! agonist
is_a: CHEBI:70781 ! PPAR modulator

[Term]
id: CHEBI:73754
name: thiosugar
def: "A carbohydrate derivative in which one or more of the oxygens or hydroxy groups of the parent carbohydrate is replaced by sulfur or -SR, where R can be hydrogen or any group." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:63299 ! carbohydrate derivative

[Term]
id: CHEBI:73755
name: 1,2-dimethylhydrazine
def: "A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24631 ! hydrazines
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018033 CHEBI:73760 ! is deprotonated form of 1,2-dimethylhydrazine(2+)

[Term]
id: CHEBI:73760
name: 1,2-dimethylhydrazine(2+)
def: "An organic cation resulting from the protonation of both of the nitrogens of 1,2-dimethylhydrazine." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:73755 ! is protonated form of 1,2-dimethylhydrazine

[Term]
id: CHEBI:73779
name: Gly-Pro zwitterion
def: "A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino terminus of Gly-Pro." []
is_a: CHEBI:90799 ! dipeptide zwitterion
relationship: RO:0018036 CHEBI:70744 ! is tautomer of Gly-Pro

[Term]
id: CHEBI:73904
name: Gly-Gly-Leu
def: "A tripeptide composed of glycine, glycine and <small>L</small>-leucine residues joined in sequence." []
is_a: CHEBI:47923 ! tripeptide
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:73913
name: antifolate
def: "An antimetabolite that impairs the action of folic acids" []
is_a: CHEBI:35221 ! antimetabolite

[Term]
id: CHEBI:73992
name: alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranose
def: "A disaccharide consisting of α-<small>L</small>-rhamnose and β-<small>D</small>-glucose linked via a 1→2 glycosidic bond." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24405 ! glycosylglucose
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:74136
name: lachrymator
def: "Any substance that stimulates the corneal nerves in the eves to cause tears." []
is_a: CHEBI:52208 ! biophysical role

[Term]
id: CHEBI:74213
name: EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor
def: "An  EC 1.17.* (oxidoreductase acting on CH or CH<small><sub>2</sub></small>) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1)." []
is_a: CHEBI:76848 ! EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor

[Term]
id: CHEBI:74222
name: gamma-lactam
def: "A lactam in which the amide bond is contained within a five-membered ring, which includes the amide nitrogen and the carbonyl carbon." []
is_a: CHEBI:24995 ! lactam

[Term]
id: CHEBI:74223
name: pyrrolidin-2-ones
def: "A pyrrolidinone in which the oxo group is at position 2 of the pyrrolidine ring." []
is_a: CHEBI:38275 ! pyrrolidinone
is_a: CHEBI:74222 ! gamma-lactam

[Term]
id: CHEBI:74224
name: genistein(1-)
def: "An organic anion that is the conjugate base of genistein, obtained by selective deprotonation of the 7-hydroxy group." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:28088 ! is deprotonated form of genistein

[Term]
id: CHEBI:74234
name: EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the activity of sepiapterin reductase (<small>L</small>-<i>erythro</i>-7,8-dihydrobiopterin forming), EC 1.1.1.153, which plays an important part in the biosynthesis of tetrahydrobiopterin." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:74236
name: polymerisation monomer
def: "Any compound used as a monomer for a polymerisation process. The term is generally used in relation to industrial polymerisation processes." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:74266
name: N-acylurea
def: "A member of the class of ureas that has the general formula R-CO-NH-CO-NH<small><sub>2</sub></small> or R-CO-NH-CO-NH-CO-R', formally derived by the acylation of one or both of the nitrogens of a urea moiety." []
is_a: CHEBI:47857 ! ureas

[Term]
id: CHEBI:74337
name: D-asparagine zwitterion
def: "A <small>D</small>-α-amino acid zwitterion that is <small>D</small>-asparagine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:28159 ! is tautomer of D-asparagine

[Term]
id: CHEBI:74338
name: D-valine zwitterion
def: "A <small>D</small>-α-amino acid zwitterion that is <small>D</small>-valine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." []
is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion
relationship: RO:0018036 CHEBI:27477 ! is tautomer of D-valine

[Term]
id: CHEBI:74345
name: 1-(5-hydroxy-2-oxo-2,3-dihydroimidazol-4-yl)urea
def: "An imidazolidinone that is imidazolin-2-one substituted at positions 4 and 5 by hydroxy and ureido groups respectively." []
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:55370 ! imidazolidinone
relationship: RO:0018036 CHEBI:15676 ! is tautomer of allantoin
relationship: RO:0018038 CHEBI:27612 ! has functional parent hydantoin

[Term]
id: CHEBI:74357
name: S-methyl methanethiosulfonate
def: "A sulfonic acid derivative obtained by condensaton of methanesulfonic acid with methanethiol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33552 ! sulfonic acid derivative
is_a: CHEBI:75521 ! thiosulfonate ester
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018038 CHEBI:16007 ! has functional parent methanethiol
relationship: RO:0018038 CHEBI:27376 ! has functional parent methanesulfonic acid

[Term]
id: CHEBI:74422
name: 4'-demethylepipodophyllotoxin
def: "An organic heterotetracyclic compound that is the 9- epimer of 4'-demethylpodophyllotoxin." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:50307 ! furonaphthodioxole
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:74440
name: epidermal growth factor receptor antagonist
def: "An antagonist at the epidermal growth factor receptor." []
is_a: CHEBI:37699 ! protein kinase inhibitor
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:74494
name: pyrimidine 5'-deoxyribonucleoside
def: "A pyrimidine deoxyribonucleoside that is a pyrimidine ribonucleoside in which the hydroxy group at the 5' position is replaced by a hydrogen." []
is_a: CHEBI:68472 ! pyrimidine deoxyribonucleoside

[Term]
id: CHEBI:74518
name: anti-obesity agent
def: "Any substance which is used to reduce or control weight." []
is_a: CHEBI:52210 ! pharmacological role

[Term]
id: CHEBI:74529
name: antidote to paracetamol poisoning
def: "A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen)." []
is_a: CHEBI:50247 ! antidote

[Term]
id: CHEBI:74530
name: antidote to curare poisoning
def: "A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare." []
is_a: CHEBI:50247 ! antidote

[Term]
id: CHEBI:74544
name: 1-oleoyl-sn-glycero-3-phosphate(2-)
def: "A 1-acyl-<em>sn</em>-glycerol 3-phosphate(2−) obtained by deprotonation of the phosphate OH groups of 1-oleoyl-<em>sn</em>-glycero-3-phosphate." []
is_a: CHEBI:57970 ! 1-acyl-sn-glycerol 3-phosphate(2-)
is_a: CHEBI:84973 ! oleoyl-sn-glycero-3-phosphate(2-)
relationship: RO:0018033 CHEBI:62837 ! is deprotonated form of 1-oleoyl-sn-glycerol 3-phosphate

[Term]
id: CHEBI:74571
name: iodoacetic acid
def: "A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom." []
is_a: CHEBI:16277 ! haloacetic acid
is_a: CHEBI:37142 ! organoiodine compound
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent

[Term]
id: CHEBI:74634
name: cardenolides
def: "Any steroid lactone that is a  C23 steroid with a five-membered lactone ring at C-17 and its substituted derivatives. They form the aglycone constituents of cardiac glycosides." []
is_a: CHEBI:26766 ! steroid lactone
is_a: CHEBI:50523 ! butenolide

[Term]
id: CHEBI:7465
name: naltrexone
def: "An  organic heteropentacyclic compound that is naloxone substituted in which the allyl group attached to the nitrogen is replaced by a cyclopropylmethyl group. A μ-opioid receptor antagonist, it is used to treat alcohol dependence." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38164 ! organic heteropentacyclic compound
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:83818 ! morphinane-like compound
relationship: RO:0000087 CHEBI:35488 ! has role central nervous system depressant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50137 ! has role mu-opioid receptor antagonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:90755 ! has role antidote to opioid poisoning
relationship: RO:0018033 CHEBI:134688 ! is deprotonated form of naltrexone(1+)

[Term]
id: CHEBI:7466
name: nandrolone
def: "A 3-oxo Δ<small><sup>4</small></sup>-steroid that is estr-4-en-3-one substituted by a β-hydroxy group at position 17." []
is_a: CHEBI:35343 ! 17beta-hydroxy steroid
is_a: CHEBI:36834 ! 3-hydroxy steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:50786 ! anabolic androgenic steroid
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018040 CHEBI:23966 ! has parent hydride estrane

[Term]
id: CHEBI:746933
name: globular protein
def: "Protein characterized by a compact, spherical shape and generally soluble in water" []
is_a: CHEBI:36080 ! protein

[Term]
id: CHEBI:746957
name: N-methylserotonin(1+)
is_a: CHEBI:131823 ! methylated primary amine(1+)
relationship: RO:0018034 CHEBI:48294 ! is protonated form of N-methylserotonin

[Term]
id: CHEBI:747163
name: Remodelin
def: "Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:747204
name: reference compound
def: "Any well-characterized compound that serves as a standard for the identification, quantification, calibration, or quality control of substances in scientific analysis." []
is_a: CHEBI:33232 ! application
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:747302
name: Centrinone
def: "Centrinone (LCR-263) is a selective and reversible inhibitor of polo-like kinase 4 (PLK4) with a Ki of 0.16 nM." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:747325
name: additive
def: "a role for a chemical additive to a mixture" []
is_a: CHEBI:33232 ! application
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:747326
name: plastic additive
def: "an additive to a plastic" []
is_a: CHEBI:747325 ! additive

[Term]
id: CHEBI:747330
name: stabilizer
def: "an additive used to preserve the structure of a material" []
is_a: CHEBI:747325 ! additive

[Term]
id: CHEBI:747331
name: plastic stabilizer
def: "an additive that stabilizes the structure of a plastic" []
is_a: CHEBI:747326 ! plastic additive
is_a: CHEBI:747330 ! stabilizer

[Term]
id: CHEBI:747332
name: filler
def: "an additive that adds mass to a substance" []
is_a: CHEBI:747325 ! additive

[Term]
id: CHEBI:747333
name: plastic filler
def: "an additive to a plastic that increases its mass" []
is_a: CHEBI:747332 ! filler

[Term]
id: CHEBI:747334
name: plastic processing aid
def: "an additive added during the production of plastics to improve the efficiency/effectiveness of production" []
is_a: CHEBI:747326 ! plastic additive

[Term]
id: CHEBI:747339
name: plastic light stabilizer
def: "a plastic additive that prevent degradation caused by light, heat, and UV from the sun" []
is_a: CHEBI:747326 ! plastic additive

[Term]
id: CHEBI:747341
name: impact modifier
def: "an additive to plastics that enhance toughness and flexibility" []
is_a: CHEBI:747326 ! plastic additive

[Term]
id: CHEBI:747342
name: polymerization initiator
def: "a substance that triggers polymerization process, leading to the formation of polymers from monomers" []
is_a: CHEBI:747345 ! polymerization aid

[Term]
id: CHEBI:747345
name: polymerization aid
def: "a substance used in the manufacturing process of polymers to facilitate the reaction, often acting as a catalyst, initiator, or solvent.  Polymerization aids are not typically intended to remain a part of the final structure" []
is_a: CHEBI:747334 ! plastic processing aid

[Term]
id: CHEBI:7476
name: naproxen
def: "A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation  and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:48851 ! methoxynaphthalene
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50629 ! has role cyclooxygenase 2 inhibitor
relationship: RO:0000087 CHEBI:50630 ! has role cyclooxygenase 1 inhibitor
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:59527 ! is protonated form of naproxen(1-)

[Term]
id: CHEBI:74783
name: astringent
def: "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:74818
name: heteroaryl hydroxy compound
def: "Any organic aromatic compound having one or more hydroxy groups attached to a heteroarene ring." []
is_a: CHEBI:33659 ! organic aromatic compound
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:74880
name: 1-dodecylguanidine
def: "A member of the class of guanidines that is guanidine in which one of the amino groups is substituted by a dodecyl group. It is used (generally as its acetate salt, known as dodine) as a agrochemical fungicide." []
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:86417 ! aliphatic nitrogen antifungal agent
relationship: BFO:0000051 CHEBI:23870 ! has part dodecyl group
relationship: BFO:0000051 CHEBI:48551 ! has part guanidino group
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018033 CHEBI:74887 ! is deprotonated form of 1-dodecylguanidine(1+)

[Term]
id: CHEBI:74887
name: 1-dodecylguanidine(1+)
def: "A guanidinium ion resulting from the protonation of the imino nitrogen of 1-dodecylguanidine. The major species at pH 7.3." []
is_a: CHEBI:60251 ! guanidinium ion
relationship: RO:0018034 CHEBI:74880 ! is protonated form of 1-dodecylguanidine

[Term]
id: CHEBI:74899
name: fluticasone furoate
def: "A trifluorinated corticosteroid that consists of 6α,9-difluoro-11β,17α-dihydroxy-17β-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:47880 ! steroid ester
is_a: CHEBI:50830 ! fluorinated steroid
is_a: CHEBI:50856 ! 2-furoate ester
is_a: CHEBI:50858 ! corticosteroid
is_a: CHEBI:51277 ! thioester
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:49167 ! has role anti-asthmatic drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0018038 CHEBI:5134 ! has functional parent fluticasone
relationship: RO:0018040 CHEBI:35509 ! has parent hydride androstane

[Term]
id: CHEBI:7492
name: nedocromil
is_a: CHEBI:26513 ! quinolines
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:35692 ! dicarboxylic acid
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:49167 ! has role anti-asthmatic drug
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0018034 CHEBI:51029 ! is protonated form of nedocromil(2-)

[Term]
id: CHEBI:74961
name: raffinose family oligosaccharide
def: "Any oligosaccharide that has a biosynthetic pathway in common with that of raffinose." []
is_a: CHEBI:50699 ! oligosaccharide

[Term]
id: CHEBI:74978
name: ginsenoside
def: "Triterpenoid saponins with a dammarane-like skeleton originally isolated from ginseng (<em>Panax</em>) species. Use of the term has been extended to include semi-synthetic derivatives." []
is_a: CHEBI:61655 ! steroid saponin
is_a: CHEBI:61778 ! triterpenoid saponin

[Term]
id: CHEBI:75045
name: dabrafenib
def: "An organofluorine compound and antineoplastic agent, used as its mesylate salt in treatment of metastatic melanoma." []
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:38418 ! 1,3-thiazoles
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75047 ! has role B-Raf inhibitor

[Term]
id: CHEBI:75047
name: B-Raf inhibitor
def: "A serine/threonine kinase inhibitor that specifically inhibits human mutant serine/threonine kinase (B-Raf)" []
is_a: CHEBI:50925 ! EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor

[Term]
id: CHEBI:75050
name: chromogenic compound
def: "Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates." []
is_a: CHEBI:50411 ! one-colour indicator

[Term]
id: CHEBI:75095
name: chrysin
def: "A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38686 ! dihydroxyflavone
is_a: CHEBI:52267 ! 7-hydroxyflavonol
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78763 ! has role EC 2.7.11.18 (myosin-light-chain kinase) inhibitor

[Term]
id: CHEBI:75190
name: EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor
def: "An EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor that interferes with the action of lysine 2,3-aminomutase (EC 5.4.3.2)." []
is_a: CHEBI:76829 ! EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor

[Term]
id: CHEBI:75212
name: dazomet
def: "A dithiocarbamic ester that is 1,3,5-thiadiazinane with a thione moiety at position 2 and in which the hydrogens attached to the nitrogens are replaced by methyl groups. A fungicide, herbicide and nematicide, it is used prior to sowing or planting for the control of soil fungi, nematodes, bacteria and germinating weeds, and as fumigant for poultry litter and eggs to control <em>Salmonella</em>. It is a non-ozone-depleting alternative to methyl bromide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38129 ! dithiocarbamic ester
is_a: CHEBI:38781 ! thiadiazinane
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:75281
name: myclobutanil
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-myclobutanil. A sterol demethylation inhibitor, it is a widely-used agricultural fungicide." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: BFO:0000051 CHEBI:83730 ! has part (R)-myclobutanil
relationship: BFO:0000051 CHEBI:83731 ! has part (S)-myclobutanil
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:75282
name: ergosterol biosynthesis inhibitor
def: "Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol." []
is_a: CHEBI:83317 ! sterol biosynthesis inhibitor

[Term]
id: CHEBI:75283
name: miltefosine
def: "A phospholipid that is the hexadecyl monoester of phosphocholine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:16247 ! phospholipid
is_a: CHEBI:36700 ! phosphocholines
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:37699 ! has role protein kinase inhibitor
relationship: RO:0000087 CHEBI:50846 ! has role immunomodulator
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent

[Term]
id: CHEBI:75284
name: (R)-2-(4-chloro-2-methylphenoxy)propanoate
def: "A monocarboxylic acid anion that is the conjugate base of (<i>R</i>)-2-(4-chloro-2-methylphenoxy)propanoic acid, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:75703 ! is deprotonated form of (R)-mecoprop
relationship: RO:0018039 CHEBI:75285 ! is enantiomer of (S)-2-(4-chloro-2-methylphenoxy)propanoate

[Term]
id: CHEBI:75285
name: (S)-2-(4-chloro-2-methylphenoxy)propanoate
def: "A monocarboxylic acid anion that is the conjugate base of (<i>S</i>)-2-(4-chloro-2-methylphenoxy)propanoic acid, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:75712 ! is deprotonated form of (S)-mecoprop
relationship: RO:0018039 CHEBI:75284 ! is enantiomer of (R)-2-(4-chloro-2-methylphenoxy)propanoate

[Term]
id: CHEBI:75287
name: (S)-dichlorprop(1-)
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of (<i>S</i>)-dichlorprop. The major species at pH 7.3" []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:75374 ! is deprotonated form of (S)-dichlorprop
relationship: RO:0018039 CHEBI:75288 ! is enantiomer of (R)-dichlorprop(1-)

[Term]
id: CHEBI:75288
name: (R)-dichlorprop(1-)
def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of (<i>R</i>)-dichlorprop. The major species at pH 7.3" []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:75373 ! is deprotonated form of (R)-dichlorprop
relationship: RO:0018039 CHEBI:75287 ! is enantiomer of (S)-dichlorprop(1-)

[Term]
id: CHEBI:75324
name: excipient
def: "A generally pharmacologically inactive substance that is formulated with the active ingredient of a medication." []
is_a: CHEBI:747332 ! filler

[Term]
id: CHEBI:75331
name: benzotriazole
def: "The simplest member of the class of benzotriazoles that consists of a benzene nucleus fused to a 1<em>H</em>-1,2,3-triazole ring." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48912 ! benzotriazoles
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:75370
name: 2-(2,4-dichlorophenoxy)propanoic acid
def: "An aromatic ether that is 2-hydroxypropanoic acid in which the hydroxy group at position 2 has been converted to its 2,4-dichlorophenyl ether." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:75373
name: (R)-dichlorprop
def: "The <i>R</i>- (active) enantiomer of dichlorprop. It is used as a herbicide for killing annual and broad leaf weeds." []
is_a: CHEBI:75370 ! 2-(2,4-dichlorophenoxy)propanoic acid
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:75380 ! has role EC 1.11.1.6 (catalase) inhibitor
relationship: RO:0018034 CHEBI:75288 ! is protonated form of (R)-dichlorprop(1-)
relationship: RO:0018039 CHEBI:75374 ! is enantiomer of (S)-dichlorprop

[Term]
id: CHEBI:75374
name: (S)-dichlorprop
def: "The <i>S</i>- (inactive) enantiomer of dichlorprop." []
is_a: CHEBI:75370 ! 2-(2,4-dichlorophenoxy)propanoic acid
relationship: RO:0018034 CHEBI:75287 ! is protonated form of (S)-dichlorprop(1-)
relationship: RO:0018039 CHEBI:75373 ! is enantiomer of (R)-dichlorprop

[Term]
id: CHEBI:75375
name: dichlorprop
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-dichlorprop. It is widely used as a herbicide for killing annual and broad leaf weeds. Only the <i>R</i>-enantiomer has herbicidal activity; the <i>S</i>-enantiomer is inactive." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:75373 ! has part (R)-dichlorprop
relationship: BFO:0000051 CHEBI:75374 ! has part (S)-dichlorprop
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:75380 ! has role EC 1.11.1.6 (catalase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:75380
name: EC 1.11.1.6 (catalase) inhibitor
def: "An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of catalase (EC 1.11.1.6)." []
is_a: CHEBI:75381 ! EC 1.11.1.* (peroxidases) inhibitor

[Term]
id: CHEBI:75381
name: EC 1.11.1.* (peroxidases) inhibitor
def: "An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*)." []
is_a: CHEBI:76738 ! EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor

[Term]
id: CHEBI:75393
name: Y-27632
def: "A monocarboxylic acid amide that is <i>trans</i>-[(1<i>R</i>)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme." []
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:50925 ! has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor

[Term]
id: CHEBI:7550
name: nicardipine
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-nicardipine. It is a calcium channel blocker which is used to treat hypertension." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:135777 ! has part (S)-nicardipine
relationship: BFO:0000051 CHEBI:180904 ! has part (R)-nicardipine
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:88230 ! has role autophagy inhibitor

[Term]
id: CHEBI:75521
name: thiosulfonate ester
def: "An organosulfur compound with the formula RSO<small><sub>2</sub></small>SR." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:7553
name: niclosamide
def: "A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:53468 ! salicylanilides
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:167183 ! has role piscicide
relationship: RO:0000087 CHEBI:33904 ! has role molluscicide
relationship: RO:0000087 CHEBI:35443 ! has role anthelminthic drug
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:87183 ! has role STAT3 inhibitor
relationship: RO:0018038 CHEBI:420128 ! has functional parent 5-chlorosalicylic acid

[Term]
id: CHEBI:7554
name: nicosulfuron
def: "A <em>N</em>-sulfonylurea that is 2-(carbamoylsulfamoyl)-<em>N</em>,<em>N</em>-dimethylpyridine-3-carboxamide substituted by a 4,6-dimethoxypyrimidin-2-yl group at the amino nitrogen." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:75596
name: EC 5.* (isomerase) inhibitor
def: "An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*)." []
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:75599
name: EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor
def: "An acid—amino-acid ligase inhibitor that inhibits the action of a glutamate—cysteine ligase (EC 6.3.2.2)" []
is_a: CHEBI:59105 ! EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor

[Term]
id: CHEBI:75600
name: EC 6.3.* (C-N bond-forming ligase) inhibitor
def: "A ligase inhibitor that interferes with the action of a <em>C</em>‒<em>N</em> bond-forming ligase (EC 6.3.*.*)." []
is_a: CHEBI:75603 ! EC 6.* (ligase) inhibitor

[Term]
id: CHEBI:75603
name: EC 6.* (ligase) inhibitor
def: "Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." []
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:75604
name: EC 6.4.* (C-C bond-forming ligase) inhibitor
def: "A ligase inhibitor that interferes with the action of a <em>C</em>‒<em>C</em> bond-forming ligase (EC 6.4.*.*)." []
is_a: CHEBI:75603 ! EC 6.* (ligase) inhibitor

[Term]
id: CHEBI:75606
name: hydroxamic acid ester
def: "A carboxamide that is a hydroxamic acid in which the hydrogen of the hydroxy group is replaced by an organyl group." []
is_a: CHEBI:37622 ! carboxamide
relationship: RO:0018038 CHEBI:24650 ! has functional parent hydroxamic acid

[Term]
id: CHEBI:7565
name: nifedipine
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:50075 ! dihydropyridine
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:66993 ! has role tocolytic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:7566
name: Nifurtimox
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87230 ! nitrofuran antibiotic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:36335 ! has role trypanocidal drug
relationship: RO:0000087 CHEBI:70868 ! has role antileishmanial agent

[Term]
id: CHEBI:7569
name: nigericin
def: "A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by <em>Streptomyces hygroscopicus</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36468 ! polycyclic ether
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:88227 ! has role potassium ionophore

[Term]
id: CHEBI:7570
name: nigerose
def: "A glycosylglucose consisting of <small>D</small>-glucose with undefined anomeric stereochemistry and an α-<small>D</small>-glucosyl residue attached at the 3-position." []
is_a: CHEBI:24405 ! glycosylglucose

[Term]
id: CHEBI:75701
name: sarin
def: "A racemate composed of equal amounts of (<i>R</i>)- and (<i>S</i>)-sarin. A potent and irreversible inhibitor of acetylcholinesterase that is toxic to the nervous system and is employed as a chemical warfare agent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:75871 ! has part (S)-sarin
relationship: BFO:0000051 CHEBI:75872 ! has part (R)-sarin
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:75703
name: (R)-mecoprop
def: "The (<i>R</i>)-enantiomer of 2-(4-chloro-2-methylphenoxy)propanoic acid; the active stereoisomer of the racemic herbicide mecoprop." []
is_a: CHEBI:75704 ! 2-(4-chloro-2-methylphenoxy)propanoic acid
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0018034 CHEBI:75284 ! is protonated form of (R)-2-(4-chloro-2-methylphenoxy)propanoate
relationship: RO:0018039 CHEBI:75712 ! is enantiomer of (S)-mecoprop

[Term]
id: CHEBI:75704
name: 2-(4-chloro-2-methylphenoxy)propanoic acid
def: "A monocarboxylic acid that is lactic acid in which the hydroxyl hydrogen is replaced by a 4-chloro-2-methylphenyl group." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0018038 CHEBI:28358 ! has functional parent rac-lactic acid

[Term]
id: CHEBI:75711
name: mecoprop
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-mecoprop." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:75703 ! has part (R)-mecoprop
relationship: BFO:0000051 CHEBI:75712 ! has part (S)-mecoprop
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:75712
name: (S)-mecoprop
def: "The (<i>S</i>)-enantiomer of 2-(4-chloro-2-methylphenoxy)propanoic acid; the inactive stereoisomer of the racemic herbicide mecoprop." []
is_a: CHEBI:75704 ! 2-(4-chloro-2-methylphenoxy)propanoic acid
relationship: RO:0018034 CHEBI:75285 ! is protonated form of (S)-2-(4-chloro-2-methylphenoxy)propanoate
relationship: RO:0018039 CHEBI:75703 ! is enantiomer of (R)-mecoprop

[Term]
id: CHEBI:75722
name: 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
def: "A tertiary alcohol that is cyclohexanol substituted at positions 1 and 2 by 3-methoxyphenyl and dimethylaminomethyl groups respectively." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0018038 CHEBI:18099 ! has functional parent cyclohexanol

[Term]
id: CHEBI:75725
name: (R,R)-tramadol
def: "A 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have <i>R</i>-configuration; the (<i>R</i>,<i>R</i>)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (<i>S</i>,<i>S</i>)-enantiomer." []
is_a: CHEBI:75722 ! 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48876 ! has role muscarinic antagonist
relationship: RO:0000087 CHEBI:48878 ! has role nicotinic antagonist
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:59282 ! has role kappa-opioid receptor agonist
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:64054 ! has role delta-opioid receptor agonist
relationship: RO:0000087 CHEBI:70774 ! has role capsaicin receptor antagonist
relationship: RO:0018033 CHEBI:75737 ! is deprotonated form of (R,R)-tramadol(1+)
relationship: RO:0018039 CHEBI:75731 ! is enantiomer of (S,S)-tramadol

[Term]
id: CHEBI:75731
name: (S,S)-tramadol
def: "A 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have <i>S</i>-configuration; the (<i>S</i>,<i>S</i>)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold lower analgesic potency than the (<i>R</i>,<i>R</i>)-enantiomer." []
is_a: CHEBI:75722 ! 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48876 ! has role muscarinic antagonist
relationship: RO:0000087 CHEBI:48878 ! has role nicotinic antagonist
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:59282 ! has role kappa-opioid receptor agonist
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:64054 ! has role delta-opioid receptor agonist
relationship: RO:0000087 CHEBI:70774 ! has role capsaicin receptor antagonist
relationship: RO:0018033 CHEBI:75738 ! is deprotonated form of (S,S)-tramadol(1+)
relationship: RO:0018039 CHEBI:75725 ! is enantiomer of (R,R)-tramadol

[Term]
id: CHEBI:75736
name: tramadol(1+)
def: "A racemate consisting of equal amounts of (<i>R</i>,<i>R</i>)- and (<i>S</i>,<i>S</i>)-tramadol(1+)." []
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:75737 ! has part (R,R)-tramadol(1+)
relationship: BFO:0000051 CHEBI:75738 ! has part (S,S)-tramadol(1+)
relationship: RO:0018034 CHEBI:9648 ! is protonated form of tramadol

[Term]
id: CHEBI:75737
name: (R,R)-tramadol(1+)
def: "An organic cation obtained by protonation of the tertiary amino group of (<i>R</i>,<i>R</i>)-tramadol." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:75725 ! is protonated form of (R,R)-tramadol
relationship: RO:0018039 CHEBI:75738 ! is enantiomer of (S,S)-tramadol(1+)

[Term]
id: CHEBI:75738
name: (S,S)-tramadol(1+)
def: "An organic cation obtained by protonation of the tertiary amino group of (<i>S</i>,<i>S</i>)-tramadol." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:75731 ! is protonated form of (S,S)-tramadol
relationship: RO:0018039 CHEBI:75737 ! is enantiomer of (R,R)-tramadol(1+)

[Term]
id: CHEBI:75763
name: eukaryotic metabolite
def: "Any  metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." []
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:75767
name: animal metabolite
def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." []
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CHEBI:75768
name: mammalian metabolite
def: "Any animal metabolite produced during a metabolic reaction in mammals." []
is_a: CHEBI:75767 ! animal metabolite

[Term]
id: CHEBI:75769
name: B vitamin
def: "Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B<small><sub>1</sub></small>, B<small><sub>2</sub></small>, B<small><sub>3</sub></small>, B<small><sub>5</sub></small>, B<small><sub>6</sub></small>, B<small><sub>7</sub></small>, B<small><sub>9</sub></small>, and B<small><sub>12</sub></small> (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0000087 CHEBI:27314 ! has role water-soluble vitamin (role)
relationship: RO:0000087 CHEBI:50733 ! has role nutraceutical

[Term]
id: CHEBI:75771
name: mouse metabolite
def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (<em>Mus musculus</em>)." []
is_a: CHEBI:75768 ! mammalian metabolite

[Term]
id: CHEBI:75772
name: Saccharomyces cerevisiae metabolite
def: "Any  fungal metabolite produced during a metabolic reaction in Baker's yeast (<em>Saccharomyces cerevisiae </em>)." []
is_a: CHEBI:76946 ! fungal metabolite

[Term]
id: CHEBI:75782
name: vitamin B complex
def: "A mixture containing all eight of the B vitamins (B<small><sub>1</sub></small>, B<small><sub>2</sub></small>, B<small><sub>3</sub></small>, B<small><sub>5</sub></small>, B<small><sub>6</sub></small>, B<small><sub>7</sub></small>, B<small><sub>9</sub></small>, and B<small><sub>12</sub></small>). It is used as a dietary supplement and as a component of growth media for microorganisms." []
is_a: CHEBI:60004 ! mixture
is_a: CHEBI:75769 ! B vitamin
relationship: BFO:0000051 CHEBI:15940 ! has part nicotinic acid
relationship: BFO:0000051 CHEBI:15956 ! has part biotin
relationship: BFO:0000051 CHEBI:17015 ! has part riboflavin
relationship: BFO:0000051 CHEBI:26948 ! has part vitamin B1
relationship: BFO:0000051 CHEBI:27306 ! has part vitamin B6
relationship: BFO:0000051 CHEBI:27470 ! has part folic acid
relationship: BFO:0000051 CHEBI:30411 ! has part cobalamin
relationship: BFO:0000051 CHEBI:46905 ! has part (R)-pantothenic acid

[Term]
id: CHEBI:75787
name: prokaryotic metabolite
def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." []
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:75832
name: iron(2+) sulfate (anhydrous)
def: "A compound of iron and sulfate in which the ratio of iron(2+) to sulfate ions is 1:1. Various hydrates occur naturally - most commonly the heptahydrate, which loses water to form the tetrahydrate at 57°C and the monohydrate at 65°C." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24873 ! iron molecular entity
is_a: CHEBI:51336 ! metal sulfate
relationship: BFO:0000051 CHEBI:29033 ! has part iron(2+)
relationship: RO:0000087 CHEBI:63247 ! has role reducing agent

[Term]
id: CHEBI:75835
name: anti-anaemic agent
def: "A compound which increases either the number of red cells or the amount of haemoglobin in the blood." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:7587
name: nitroalkane
def: "A nitrohydrocarbon that is an alkane in which one of the hydrogens has been replaced by a nitro group." []
is_a: CHEBI:51129 ! nitrohydrocarbon

[Term]
id: CHEBI:75871
name: (S)-sarin
def: "The (<i>S</i>)-enantiomer of sarin; the more potent enantiomer of racemic sarin, a nerve agent that is employed as a chemical warfare agent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:75873 ! isopropyl methylphosphonofluoridate
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0018039 CHEBI:75872 ! is enantiomer of (R)-sarin

[Term]
id: CHEBI:75872
name: (R)-sarin
def: "The (<i>S</i>)-enantiomer of sarin; the less active enantiomer of racemic sarin, a nerve agent that is employed as a chemical warfare agent." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:75873 ! isopropyl methylphosphonofluoridate
relationship: RO:0000087 CHEBI:38462 ! has role EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0018039 CHEBI:75871 ! is enantiomer of (S)-sarin

[Term]
id: CHEBI:75873
name: isopropyl methylphosphonofluoridate
def: "A phosphinic ester that is the isopropyl ester of methylphosphonofluoridic acid." []
is_a: CHEBI:24062 ! fluorine molecular entity
is_a: CHEBI:26043 ! phosphinic ester

[Term]
id: CHEBI:75874
name: para-terphenyl
def: "A ring assembly based on a 1,4-diphenylbenzene skeleton and its substituted derivatives thereof." []
is_a: CHEBI:33836 ! benzenoid aromatic compound
is_a: CHEBI:36820 ! ring assembly

[Term]
id: CHEBI:75884
name: N-acylindole
def: "A carboxamide resulting from the formal condensation of a carboxylic acid with the nitrogen of an indole." []
is_a: CHEBI:24828 ! indoles
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:75885
name: 2-pyranones
def: "A pyranone based on the structure of 2<em>H</em>-pyran-2-one and its substituted derivatives." []
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:37963 ! pyranone

[Term]
id: CHEBI:7590
name: nitrofen
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:73192 ! has role EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor

[Term]
id: CHEBI:75902
name: hispidulin
def: "A monomethoxyflavone that is scutellarein methylated at position 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25401 ! monomethoxyflavone
is_a: CHEBI:27116 ! trihydroxyflavone
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018038 CHEBI:9062 ! has functional parent scutellarein

[Term]
id: CHEBI:75954
name: vancomycin aglycone zwitterion
def: "A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino group of vancomycin aglycone." []
is_a: CHEBI:60466 ! peptide zwitterion
relationship: RO:0018034 CHEBI:77981 ! is protonated form of vancomycin aglycone(1-)
relationship: RO:0018036 CHEBI:47724 ! is tautomer of vancomycin aglycone

[Term]
id: CHEBI:75955
name: copper(II) oxide
def: "A metal oxide that has the formula CuO. It has an ionic structure." []
is_a: CHEBI:134069 ! copper oxide
relationship: BFO:0000051 CHEBI:29036 ! has part copper(2+)

[Term]
id: CHEBI:7596
name: nitroprusside
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33892 ! iron coordination entity
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent

[Term]
id: CHEBI:75991
name: trametinib dimethyl sulfoxide
def: "An addition compound obtained by combining equimolar amounts of trametinib and dimethyl sulfoxide. Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35504 ! addition compound
relationship: BFO:0000051 CHEBI:28262 ! has part dimethyl sulfoxide
relationship: BFO:0000051 CHEBI:75998 ! has part trametinib
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:79091 ! has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

[Term]
id: CHEBI:75998
name: trametinib
def: "A pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38932 ! pyridopyrimidine
is_a: CHEBI:51454 ! cyclopropanes
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:79091 ! has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

[Term]
id: CHEBI:76004
name: dimethyl fumarate
def: "An enoate ester resulting from the formal condensation of both carboxy groups of fumaric acid with methanol. Used for treatment of adults with relapsing forms of multiple sclerosis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:35748 ! fatty acid ester
is_a: CHEBI:51307 ! diester
is_a: CHEBI:51702 ! enoate ester
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0018038 CHEBI:18012 ! has functional parent fumaric acid

[Term]
id: CHEBI:76010
name: dolutegravir
def: "A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (4<i>R</i>,12a<i>S</i>)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2<em>H</em>-pyrido[1',2':4,5]pyrazino[2,1-<em>b</em>][1,3]oxazine-9-carboxylic acid with the amino group of 2,4-difluorobenzylamine. Used (as its sodium salt) for treatment of HIV-1." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:38582 ! difluorobenzene
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:67268 ! has role HIV-1 integrase inhibitor
relationship: RO:0018034 CHEBI:76014 ! is protonated form of dolutegravir(1-)

[Term]
id: CHEBI:76014
name: dolutegravir(1-)
def: "An organic anion that is the conjugate base of dolutegravir, obtained by deptotonation of the 7-hydroxy group." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:76010 ! is deprotonated form of dolutegravir

[Term]
id: CHEBI:76042
name: aromatic amino-acid zwitterion
def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:33856 ! is tautomer of aromatic amino acid

[Term]
id: CHEBI:76172
name: loxoprofen
def: "A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted into its active <i>trans</i>-alcohol metabolite following oral administration." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:36140 ! cyclopentanones
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35481 ! has role non-narcotic analgesic
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:35544 ! has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0018034 CHEBI:76199 ! is protonated form of loxoprofen(1-)
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:76199
name: loxoprofen(1-)
def: "An oxo monocarboxylic acid anion that is the conjugate base of loxoprofen, obtained by deprotonation of the carboxy group." []
is_a: CHEBI:35902 ! oxo monocarboxylic acid anion
relationship: RO:0018033 CHEBI:76172 ! is deprotonated form of loxoprofen

[Term]
id: CHEBI:76206
name: xenobiotic metabolite
def: "Any metabolite produced by metabolism of a xenobiotic compound." []
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:76212
name: triphenylmethane
def: "A triarylmethane in which the three aryl groups are phenyl. It forms the basic skeleton of several synthetic dyes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:76214 ! triarylmethane
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:76214
name: triarylmethane
def: "Any benzenoid aromatic compound containing three aryl groups connected by a single C atom." []
is_a: CHEBI:33836 ! benzenoid aromatic compound

[Term]
id: CHEBI:7622
name: norathyriol
def: "A member of the class of xanthones that is 9<em>H</em>-xanthen-9-one substituted by hydroxy groups at positions 1, 3, 6 and 7. Isolated from <em>Garcinia mangostana</em> and <em>Maclura pomifera</em>, it exhibits inhibitory activity against protein kinase C." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:51149 ! xanthones
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37700 ! has role EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:76224
name: aromatic ketone
def: "A ketone in which the carbonyl group is attached to an aromatic ring." []
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:76250
name: hydroxyisoflavans
def: "A member of the class of isoflavans in which one or more ring hydrogens are replaced by hydroxy groups." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:72572 ! isoflavans

[Term]
id: CHEBI:76261
name: 1-nitropropane
def: "A nitroalkane that is propane substituted at C-1 by a nitro group." []
is_a: CHEBI:133972 ! primary nitroalkane
relationship: RO:0018040 CHEBI:32879 ! has parent hydride propane

[Term]
id: CHEBI:76282
name: suberate(2-)
is_a: CHEBI:132953 ! suberate
is_a: CHEBI:133291 ! saturated dicarboxylic acid dianion(2-)

[Term]
id: CHEBI:76287
name: pentachloroethane
def: "A member of the class of chloroethanes that is ethane in which five of the six hydrogens are replaced by chlorines. A non-flammable, high-boiling liquid (b.p. 161-162°C) with relative density 1.67 and an odour resembling that of chloroform, it is used as a solvent for oil and grease, in metal cleaning, and in the separation of coal from impurities." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36016 ! chloroethanes
relationship: RO:0000087 CHEBI:48355 ! has role non-polar solvent

[Term]
id: CHEBI:7630
name: norgestrel
def: "A racemate comprising equimolar amounts of levonorgestrel and dextronorgestrel." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:50900 ! has part dextronorgestrel
relationship: BFO:0000051 CHEBI:6443 ! has part levonorgestrel
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:49326 ! has role synthetic oral contraceptive
relationship: RO:0000087 CHEBI:59826 ! has role progestin
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent

[Term]
id: CHEBI:76307
name: omega-hydroxy fatty acid anion
def: "A hydroxy fatty acid anion obtained by deprotonation of the carboxy group of any ω-hydroxy fatty acid; major species at pH 7.3." []
is_a: CHEBI:59835 ! hydroxy fatty acid anion
relationship: RO:0018033 CHEBI:10615 ! is deprotonated form of omega-hydroxy fatty acid

[Term]
id: CHEBI:76324
name: N-nitrosopiperidine
def: "A nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite." []
is_a: CHEBI:18049 ! piperidine
is_a: CHEBI:35803 ! nitrosamine
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:76326
name: N-nitrosomorpholine
def: "A nitrosamine that is morpholine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. A carcinogen and mutagen, it is found in snuff tobacco." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35803 ! nitrosamine
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:76329
name: 3-methyl-4'-dimethylaminoazobenzene
def: "A member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 3 by a methyl group, while the other is substituted at position 4 by a dimethylamino group. It is a potent liver carcinogen." []
is_a: CHEBI:22682 ! azobenzenes
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:7640
name: nortriptyline
def: "An organic tricyclic compound that is 10,11-dihydro-5<em>H</em>-dibenzo[<em>a,d</em>][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of  amitriptyline." []
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:51959 ! organic tricyclic compound
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0018038 CHEBI:2666 ! has functional parent amitriptyline
relationship: RO:0018040 CHEBI:35642 ! has parent hydride dibenzo[a,d][7]annulene

[Term]
id: CHEBI:76413
name: greenhouse gas
def: "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:76414
name: propellant
def: "A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:76507
name: marine metabolite
def: "Any metabolite produced during a metabolic reaction in marine macro- and microorganisms." []
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:76530
name: sn-glycero-3-monophosphate(2-)
def: "An anionic phospholipid having a phosphate group at <em>sn</em>-3 position of the glycerol backbone, and with a combination of one or two acyl groups, alkyl groups, or alkenyl groups attached at the <em>sn</em>-1 and <em>sn</em>-2 positions through ester, ether or vinyl linkages respectively." []
is_a: CHEBI:78185 ! glycero-3-monophosphate(2-)

[Term]
id: CHEBI:76551
name: N-nitrosoureas
def: "A nitroso compound that is any urea in which one of the nitrogens is substituted by a nitroso group" []
is_a: CHEBI:35800 ! nitroso compound
is_a: CHEBI:47857 ! ureas

[Term]
id: CHEBI:76567
name: polyunsaturated fatty acid anion
def: "Any unsaturated fatty acid anion containing more than one C-C unsaturated bond.  Major species at pH 7.3." []
is_a: CHEBI:2580 ! unsaturated fatty acid anion
relationship: RO:0018033 CHEBI:26208 ! is deprotonated form of polyunsaturated fatty acid

[Term]
id: CHEBI:76579
name: triradylglycerol
def: "Any glycerolipid that is glycerol bearing three substituent groups - either acyl, alkyl, or alk-1-enyl at each of the three possible positions." []
is_a: CHEBI:35741 ! glycerolipid

[Term]
id: CHEBI:76595
name: nephroprotective agent
def: "Any protective agent that is able to prevent damage to the kidney." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:7660
name: nystatin
def: "A heterogeneous mixture of polyene compounds produced by cultures of <em>Streptomyces noursei</em>. It mainly consists of three biologically active components designated nystatin A<small><sub>1</sub></small>, nystatin A<small><sub>2</sub></small>, and nystatin A<small><sub>3</sub></small>. It is used to treat oral and dermal fungal infections." []
is_a: CHEBI:22507 ! aminoglycoside antibiotic
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:26191 ! polyol
is_a: CHEBI:36244 ! dicarboxylic acid monoester
is_a: CHEBI:48121 ! polyene
is_a: CHEBI:60004 ! mixture
is_a: CHEBI:87113 ! antibiotic antifungal drug
relationship: BFO:0000051 CHEBI:192979 ! has part nystatin A2
relationship: BFO:0000051 CHEBI:31927 ! has part nystatin A3
relationship: BFO:0000051 CHEBI:473992 ! has part nystatin A1
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:76603
name: chlorendic acid
def: "A bridged organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with maleic anhydride followed by hydrolysis of the resulting anhydride. A chemical intermediate used in the preparation of fire-retardant polyester resins and plasticisers." []
is_a: CHEBI:35692 ! dicarboxylic acid
is_a: CHEBI:35990 ! bridged compound
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:76612
name: ibrutinib
def: "A member of the class of acrylamides that is (3<i>R</i>)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-<em>d</em>]pyrimidin-1-yl]piperidine in which the piperidine nitrogen is replaced by an acryloyl group. A selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase, it is used for treatment of B-cell malignancies." []
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:22216 ! acrylamides
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38669 ! pyrazolopyrimidine
is_a: CHEBI:48591 ! N-acylpiperidine
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76617 ! has role EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

[Term]
id: CHEBI:76617
name: EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
def: "An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2)." []
is_a: CHEBI:38637 ! tyrosine kinase inhibitor
is_a: CHEBI:76817 ! EC 2.7.10.* (protein-tyrosine kinase) inhibitor

[Term]
id: CHEBI:76619
name: omega-methyl fatty acid anion
def: "A fatty acid anion obtained by deprotonation of the carboxy group of any ω-methyl fatty acid; major species at pH 7.3." []
is_a: CHEBI:28868 ! fatty acid anion

[Term]
id: CHEBI:76629
name: 2-lysophosphatidic acid
def: "Any member of the class of lysophosphatidic acids which has a free hydroxy group at the 2-position of the glycerol moiety." []
is_a: CHEBI:132742 ! lysophosphatidic acid
relationship: RO:0018034 CHEBI:78166 ! is protonated form of 2-lysophosphatidate(2-)

[Term]
id: CHEBI:76655
name: EC 2.1.* (C1-transferase) inhibitor
def: "A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*)." []
is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor

[Term]
id: CHEBI:76660
name: EC 2.2.* (aldehyde or ketone transferase) inhibitor
def: "A transferase inhibitor interfering with the action of any transferase that transfers an aldehyde or ketone group (EC 2.2.*.*)." []
is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor

[Term]
id: CHEBI:76661
name: EC 2.3.* (acyltransferase) inhibitor
def: "A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*)." []
is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor

[Term]
id: CHEBI:76662
name: EC 2.4.* (glycosyltransferase) inhibitor
def: "A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*)." []
is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor

[Term]
id: CHEBI:76663
name: EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor
def: "A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*)." []
is_a: CHEBI:76834 ! EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor

[Term]
id: CHEBI:76668
name: EC 2.7.* (P-containing group transferase) inhibitor
def: "A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*)." []
is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor

[Term]
id: CHEBI:76694
name: EC 5.3.* (intramolecular oxidoreductase) inhibitor
def: "An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*)." []
is_a: CHEBI:75596 ! EC 5.* (isomerase) inhibitor

[Term]
id: CHEBI:76695
name: EC 5.4.* (intramolecular transferase) inhibitor
def: "An isomerase inhibitor that interferes with the action of an intramolecular transferase (EC 5.4.*.*)." []
is_a: CHEBI:75596 ! EC 5.* (isomerase) inhibitor

[Term]
id: CHEBI:76697
name: EC 5.99.* (other isomerases) inhibitor
def: "An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*)." []
is_a: CHEBI:75596 ! EC 5.* (isomerase) inhibitor

[Term]
id: CHEBI:76707
name: EC 6.2.* (C-S bond-forming ligase) inhibitor
def: "A ligase inhibitor that interferes with the action of a <em>C</em>‒<em>S</em> bond-forming ligase (EC 6.2.*.*)." []
is_a: CHEBI:75603 ! EC 6.* (ligase) inhibitor

[Term]
id: CHEBI:76710
name: EC 4.* (lyase) inhibitor
def: "An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving <em>C</em>‒<em>C</em>, <em>C</em>‒<em>O</em>, <em>C</em>‒<em>N</em> and other bonds by other means than by hydrolysis or oxidation." []
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:76711
name: EC 4.1.* (C-C lyase) inhibitor
def: "A lyase inhibitor which inhibits the action of a <em>C</em>‒<em>C</em> lyase (EC 4.1.*.*)." []
is_a: CHEBI:76710 ! EC 4.* (lyase) inhibitor

[Term]
id: CHEBI:76712
name: EC 4.2.* (C-O lyase) inhibitor
def: "A lyase inhibitor which inhibits the action of a <em>C</em>‒<em>O</em> lyase (EC 4.2.*.*)." []
is_a: CHEBI:76710 ! EC 4.* (lyase) inhibitor

[Term]
id: CHEBI:76713
name: EC 4.3.* (C-N lyase) inhibitor
def: "A lyase inhibitor which inhibits the action of a <em>C</em>‒<em>N</em> lyase (EC 4.3.*.*)." []
is_a: CHEBI:76710 ! EC 4.* (lyase) inhibitor

[Term]
id: CHEBI:76716
name: EC 4.6.* (P-O lyase) inhibitor
def: "A lyase inhibitor which inhibits the action of a <em>P</em>‒<em>O</em> lyase (EC 4.6.*.*)." []
is_a: CHEBI:76710 ! EC 4.* (lyase) inhibitor

[Term]
id: CHEBI:76725
name: EC 1.* (oxidoreductase) inhibitor
def: "An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*)." []
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:76726
name: EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76727
name: EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76729
name: EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76730
name: EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH‒NH<small><sub>2</sub></small> group of donors (EC 1.4.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76731
name: EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76733
name: EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on  NADH or NADPH (EC 1.6.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76735
name: EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76736
name: EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76737
name: EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on diphenols and related substances as donors (EC 1.10.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76738
name: EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76740
name: EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76741
name: EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76744
name: EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH<small><sub>2</sub></small> (EC 1.17.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76748
name: EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor
def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*.*)." []
is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor

[Term]
id: CHEBI:76759
name: EC 3.* (hydrolase) inhibitor
def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." []
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:76760
name: EC 3.1.* (ester hydrolase) inhibitor
def: "A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*)." []
is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor

[Term]
id: CHEBI:76761
name: EC 3.2.* (glycosylase) inhibitor
def: "A hydrolase inhibitor that interferes with the action of any glycosylase (EC 3.2.*.*)." []
is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor

[Term]
id: CHEBI:76764
name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor
def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." []
is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor

[Term]
id: CHEBI:76773
name: EC 3.1.1.* (carboxylic ester hydrolase) inhibitor
def: "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*)." []
is_a: CHEBI:76760 ! EC 3.1.* (ester hydrolase) inhibitor

[Term]
id: CHEBI:76775
name: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor
def: "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*)." []
is_a: CHEBI:76760 ! EC 3.1.* (ester hydrolase) inhibitor

[Term]
id: CHEBI:76777
name: poly(inosinic acid)
def: "A polynucleotide comprised of inosine units connected via 3'→5' phosphodiester linkages." []
is_a: CHEBI:15986 ! polynucleotide
relationship: BFO:0000051 CHEBI:76778 ! has part IMP residue

[Term]
id: CHEBI:76778
name: IMP residue
def: "A canonical ribonucleotide residue derived from IMP." []
is_a: CHEBI:50299 ! canonical ribonucleotide residue
relationship: RO:0018034 CHEBI:82852 ! is protonated form of inosine 5'-phosphate(1-) residue
relationship: RO:0018037 CHEBI:17202 ! is substitutent group from IMP

[Term]
id: CHEBI:76779
name: EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
def: "Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26)." []
is_a: CHEBI:5924 ! EC 3.4.21.* (serine endopeptidase) inhibitor

[Term]
id: CHEBI:76782
name: EC 3.4.15.* (peptidyl-dipeptidase) inhibitor
def: "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a peptidyl dipeptidase (EC 3.4.15.*)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:76785
name: EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor
def: "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*)." []
is_a: CHEBI:76760 ! EC 3.1.* (ester hydrolase) inhibitor

[Term]
id: CHEBI:76787
name: EC 3.4.11.* (aminopeptidase) inhibitor
def: "An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes wtih the action of any aminopeptidase (EC 3.4.11.*)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:76788
name: EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor
def: "An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of any dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:76789
name: EC 2.4.1.* (hexosyltransferase) inhibitor
def: "An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*)." []
is_a: CHEBI:76662 ! EC 2.4.* (glycosyltransferase) inhibitor

[Term]
id: CHEBI:76790
name: EC 2.4.2.* (pentosyltransferase) inhibitor
def: "An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*)." []
is_a: CHEBI:76662 ! EC 2.4.* (glycosyltransferase) inhibitor

[Term]
id: CHEBI:76796
name: EC 3.4.22.* (cysteine endopeptidase) inhibitor
def: "An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:76797
name: EC 2.5.1.18 (glutathione transferase) inhibitor
def: "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18)." []
is_a: CHEBI:76663 ! EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor

[Term]
id: CHEBI:76807
name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor
def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." []
is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor

[Term]
id: CHEBI:76808
name: EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor
def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*)." []
is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor

[Term]
id: CHEBI:76811
name: EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor
def: "An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of sphingomyelin phosphodiesterase (EC 3.1.4.12)." []
is_a: CHEBI:50218 ! EC 3.1.4.* (phosphoric diester hydrolase) inhibitor

[Term]
id: CHEBI:76812
name: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*)." []
is_a: CHEBI:37699 ! protein kinase inhibitor

[Term]
id: CHEBI:76815
name: EC 2.7.7.* (nucleotidyltransferase) inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*)." []
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:76816
name: EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category." []
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:76817
name: EC 2.7.10.* (protein-tyrosine kinase) inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of any protein-tyrosine kinase (EC 2.7.10.*)." []
is_a: CHEBI:37699 ! protein kinase inhibitor

[Term]
id: CHEBI:76823
name: EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor
def: "An EC 6.3.* (<em>C</em>‒<em>N</em> bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*)." []
is_a: CHEBI:75600 ! EC 6.3.* (C-N bond-forming ligase) inhibitor

[Term]
id: CHEBI:76824
name: EC 6.4.1.* (carboxylase) inhibitor
def: "An EC 6.4.* (<em>C</em>‒<em>C</em> bond-forming ligase) inhibitor that interferes with the action of a carboxylating enzyme (EC 6.4.1.*)." []
is_a: CHEBI:75604 ! EC 6.4.* (C-C bond-forming ligase) inhibitor

[Term]
id: CHEBI:76829
name: EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor
def: "An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring amino groups (EC 5.4.3.*)." []
is_a: CHEBI:76695 ! EC 5.4.* (intramolecular transferase) inhibitor

[Term]
id: CHEBI:76830
name: EC 5.99.1.* (miscellaneous isomerase) inhibitor
def: "An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class." []
is_a: CHEBI:76697 ! EC 5.99.* (other isomerases) inhibitor

[Term]
id: CHEBI:76832
name: EC 4.3.1.* (ammonia-lyase) inhibitor
def: "An EC 4.3.* (<em>C</em>‒<em>N</em> lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*)." []
is_a: CHEBI:76713 ! EC 4.3.* (C-N lyase) inhibitor

[Term]
id: CHEBI:76834
name: EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor
def: "An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*)." []
is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor

[Term]
id: CHEBI:76835
name: EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
def: "An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor (EC 1.1.1.*)." []
is_a: CHEBI:76726 ! EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor

[Term]
id: CHEBI:76836
name: EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor
def: "An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.1.3.*)." []
is_a: CHEBI:76726 ! EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor

[Term]
id: CHEBI:76837
name: EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor
def: "An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*)." []
is_a: CHEBI:76740 ! EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor

[Term]
id: CHEBI:76838
name: EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
def: "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*)." []
is_a: CHEBI:76741 ! EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

[Term]
id: CHEBI:76840
name: EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
def: "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any enzyme in the EC 1.14.99.* (miscellaneous) category." []
is_a: CHEBI:76741 ! EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

[Term]
id: CHEBI:76841
name: EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
def: "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*)." []
is_a: CHEBI:76741 ! EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

[Term]
id: CHEBI:76842
name: vancomycin(1+)
def: "An organic cation that is the conjugate acid of vancomycin, obtained by deprotonation of the carboxy group and protonation of the two amino functions; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:28001 ! is protonated form of vancomycin

[Term]
id: CHEBI:76845
name: EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor
def: "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using a miscellaneous compound as one donor and incorporating one atom of oxygen (EC 1.14.18.*)." []
is_a: CHEBI:76741 ! EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

[Term]
id: CHEBI:76848
name: EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor
def: "An EC 1.17.* (oxidoreductase acting on CH or CH<small><sub>2</sub></small>) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*)." []
is_a: CHEBI:76744 ! EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor

[Term]
id: CHEBI:76850
name: EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor
def: "An EC 1.17.* (oxidoreductase acting on CH or CH<small><sub>2</sub></small>) inhibitor that interferes with the function of any such enzyme that uses oxygen as acceptor (EC 1.17.3.*)." []
is_a: CHEBI:76744 ! EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor

[Term]
id: CHEBI:76852
name: EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor
def: "An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor (EC 1.2.1.*)." []
is_a: CHEBI:76727 ! EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor

[Term]
id: CHEBI:76853
name: EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor
def: "An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*)." []
is_a: CHEBI:76727 ! EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor

[Term]
id: CHEBI:76857
name: EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor
def: "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor (EC 1.3.1.*)." []
is_a: CHEBI:76729 ! EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor

[Term]
id: CHEBI:76858
name: EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitor
def: "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other, known, acceptors) category." []
is_a: CHEBI:76729 ! EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor

[Term]
id: CHEBI:76859
name: EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitor
def: "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other acceptors) category." []
is_a: CHEBI:76729 ! EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor

[Term]
id: CHEBI:76860
name: EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor
def: "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.3.3.*)." []
is_a: CHEBI:76729 ! EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor

[Term]
id: CHEBI:76861
name: EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor
def: "An EC 1.4.* (oxidoreductase acting on donor CH-NH<small><sub>2</sub></small> group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*)." []
is_a: CHEBI:76730 ! EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor

[Term]
id: CHEBI:76863
name: EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor
def: "An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor (EC 1.5.1.*)." []
is_a: CHEBI:76731 ! EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor

[Term]
id: CHEBI:76866
name: EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor
def: "An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*)." []
is_a: CHEBI:76733 ! EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor

[Term]
id: CHEBI:76869
name: EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor
def: "An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor (EC 1.8.1.*)." []
is_a: CHEBI:76735 ! EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor

[Term]
id: CHEBI:76870
name: EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor
def: "An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*)." []
is_a: CHEBI:76736 ! EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor

[Term]
id: CHEBI:76871
name: EC 2.1.1.* (methyltransferases) inhibitor
def: "An EC 2.1.* (C<small><sub>1</sub></small>-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*)." []
is_a: CHEBI:76655 ! EC 2.1.* (C1-transferase) inhibitor

[Term]
id: CHEBI:76874
name: EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor
def: "An EC 2.1.* (C<small><sub>1</sub></small>-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*)." []
is_a: CHEBI:76655 ! EC 2.1.* (C1-transferase) inhibitor

[Term]
id: CHEBI:76876
name: EC 2.2.1.* (transketolase/transaldolase) inhibitor
def: "An EC 2.2.* (aldehyde or ketone transferase) inhibitor that interferes with the action of any (transketolase or transaldolase (EC 2.2.1.*)." []
is_a: CHEBI:76660 ! EC 2.2.* (aldehyde or ketone transferase) inhibitor

[Term]
id: CHEBI:76878
name: EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor
def: "An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*)." []
is_a: CHEBI:76661 ! EC 2.3.* (acyltransferase) inhibitor

[Term]
id: CHEBI:76881
name: EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*)." []
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:76891
name: EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor
def: "An EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of cytosol alanyl aminopeptidase (EC 3.4.11.14)." []
is_a: CHEBI:76787 ! EC 3.4.11.* (aminopeptidase) inhibitor

[Term]
id: CHEBI:76893
name: EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor
def: "An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that interferes with the action of dipeptidyl-peptidase II (EC 3.4.14.2)." []
is_a: CHEBI:76788 ! EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor

[Term]
id: CHEBI:76895
name: EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor
def: "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*)." []
is_a: CHEBI:73216 ! EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor

[Term]
id: CHEBI:76898
name: EC 1.14.14.1 (unspecific monooxygenase) inhibitor
def: "An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1)." []
is_a: CHEBI:76838 ! EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor

[Term]
id: CHEBI:76902
name: EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
def: "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the function of any such enzyme using 2-oxoglutarate as one donor and incorporating one atom each of oxygen into both donors (EC 1.14.11.*)." []
is_a: CHEBI:76741 ! EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor

[Term]
id: CHEBI:76906
name: EC 4.1.1.* (carboxy-lyase) inhibitor
def: "An EC 4.1.* (<em>C</em>‒<em>C</em> lyase) inhibitor that interferes with the action of any carboxy-lyase (EC 4.1.1.*)." []
is_a: CHEBI:76711 ! EC 4.1.* (C-C lyase) inhibitor

[Term]
id: CHEBI:76907
name: EC 4.2.1.* (hydro-lyases) inhibitor
def: "An EC 4.2.* (<em>C</em>‒<em>O</em> lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*)." []
is_a: CHEBI:76712 ! EC 4.2.* (C-O lyase) inhibitor

[Term]
id: CHEBI:76916
name: hyperglycemic agent
def: "A drug which increases the blood glucose level." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:76924
name: plant metabolite
def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." []
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CHEBI:76926
name: EC 3.4.13.19 (membrane dipeptidase) inhibitor
def: "An EC 3.4.13.* (dipeptidase) inhibitor that interferes with the action of membrane dipeptidase (EC 3.4.13.19)." []
is_a: CHEBI:59499 ! EC 3.4.13.* (dipeptidase) inhibitor

[Term]
id: CHEBI:76928
name: 2,3-saturated fatty acid(1-)
def: "A fatty acid anion obtained by deprotonation of the carboxy group of any 2,3-saturated fatty acid." []
is_a: CHEBI:83955 ! 2-saturated fatty acid anion
relationship: RO:0018033 CHEBI:76929 ! is deprotonated form of 2,3-saturated fatty acid

[Term]
id: CHEBI:76929
name: 2,3-saturated fatty acid
def: "Any fatty acid in which the first two carbons of the chain attached to the carboxy group are saturated and unbranched." []
is_a: CHEBI:35366 ! fatty acid
relationship: RO:0018034 CHEBI:76928 ! is protonated form of 2,3-saturated fatty acid(1-)

[Term]
id: CHEBI:76932
name: pathway inhibitor
def: "An enzyme inhibitor that interferes with one or more steps in a metabolic pathway." []
is_a: CHEBI:23924 ! enzyme inhibitor

[Term]
id: CHEBI:76938
name: EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor
def: "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on ATP and involved in cellular and subcellular movement (EC 3.6.4.*)." []
is_a: CHEBI:73216 ! EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor

[Term]
id: CHEBI:76939
name: EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor
def: "An EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor that interferes with the action of a non-chaperonin molecular chaperone ATPase (EC 3.6.4.10)." []
is_a: CHEBI:76938 ! EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor

[Term]
id: CHEBI:76946
name: fungal metabolite
def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." []
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CHEBI:76956
name: Aspergillus metabolite
def: "Any fungal metabolite produced during a metabolic reaction in the mould, <em>Aspergillus </em>." []
is_a: CHEBI:76946 ! fungal metabolite

[Term]
id: CHEBI:76964
name: Penicillium metabolite
def: "Any fungal metabolite produced during a metabolic reaction in <em>Penicillium</em>." []
is_a: CHEBI:76946 ! fungal metabolite

[Term]
id: CHEBI:76967
name: human xenobiotic metabolite
def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." []
is_a: CHEBI:76206 ! xenobiotic metabolite
is_a: CHEBI:77746 ! human metabolite

[Term]
id: CHEBI:76968
name: fungal xenobiotic metabolite
def: "Any fungal  metabolite produced by metabolism of a xenobiotic compound in fungi." []
is_a: CHEBI:76206 ! xenobiotic metabolite
is_a: CHEBI:76946 ! fungal metabolite

[Term]
id: CHEBI:76969
name: bacterial metabolite
def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." []
is_a: CHEBI:75787 ! prokaryotic metabolite

[Term]
id: CHEBI:76971
name: Escherichia coli metabolite
def: "Any bacterial metabolite produced during a metabolic reaction in <em>Escherichia coli</em>." []
is_a: CHEBI:76969 ! bacterial metabolite

[Term]
id: CHEBI:76976
name: bacterial xenobiotic metabolite
def: "Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria." []
is_a: CHEBI:76206 ! xenobiotic metabolite
is_a: CHEBI:76969 ! bacterial metabolite

[Term]
id: CHEBI:76983
name: N-sulfonylurea
def: "A urea in which one of the hydrogens attached to a nitrogen of the urea group is replaced by a sulfonyl group. The <em>N</em>-sulfonylurea moiety is a key group in various herbicides, as well as in a number of antidiabetic drugs used in the management of type 2 diabetis mellitus." []
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:47857 ! ureas

[Term]
id: CHEBI:76988
name: xenoestrogen
def: "A synthetic or semi-synthetic compound that has oestrogenic activity." []
is_a: CHEBI:138015 ! endocrine disruptor
is_a: CHEBI:50114 ! estrogen

[Term]
id: CHEBI:76989
name: phytoestrogen
def: "Any compound produced by a plant that happens to have estrogenic activity." []
is_a: CHEBI:50114 ! estrogen

[Term]
id: CHEBI:76990
name: mycoestrogen
def: "Any compound produced by a fungus that happens to have estrogenic activity." []
is_a: CHEBI:50114 ! estrogen

[Term]
id: CHEBI:77016
name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate
def: "A polyunsaturated fatty acid anion that is the conjugate base of (4<i>Z</i>,7<i>Z</i>,10<i>Z</i>,13<i>Z</i>,16<i>Z</i>,19<i>Z</i>)-docosahexaenoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:149500 ! (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl derivative
is_a: CHEBI:78060 ! docosahexaenoate
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28125 ! is deprotonated form of all-cis-docosa-4,7,10,13,16,19-hexaenoic acid

[Term]
id: CHEBI:77019
name: EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor
def: "An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme in the EC 1.10.99.* category." []
is_a: CHEBI:76737 ! EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor

[Term]
id: CHEBI:77020
name: EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor
def: "An EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor that interferes with the action of ribosyldihydronicotinamide dehydrogenase (quinone), EC 1.10.99.2." []
is_a: CHEBI:77019 ! EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor

[Term]
id: CHEBI:77024
name: EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor
def: "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41)." []
is_a: CHEBI:76775 ! EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor

[Term]
id: CHEBI:77034
name: mucolytic
def: "A compound that alters the structure of mucus so as to decrease its viscosity and thereby facilitate its removal by ciliary action and expectoration. Compare with <em>antitussives</em>, which suppress the cough reflex, and <em>expectorants</em>, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:77035
name: expectorant
def: "Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with <em>mucolytics</em>, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and <em>antitussives</em>, which suppress the cough reflex." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:77047
name: tylosin(1+)
def: "An organic cation that is the conjugate acid of tylosin, obtained by protonation of the tertiary amino group; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:17658 ! is protonated form of tylosin

[Term]
id: CHEBI:77090
name: EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
def: "An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of serine-sulfate ammonia-lyase (EC 4.3.1.10)." []
is_a: CHEBI:76832 ! EC 4.3.1.* (ammonia-lyase) inhibitor

[Term]
id: CHEBI:77102
name: EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor
def: "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*)." []
is_a: CHEBI:76729 ! EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor

[Term]
id: CHEBI:77103
name: EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor
def: "An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of dihydroorotate dehydrogenase (quinone), EC 1.3.5.2." []
is_a: CHEBI:77102 ! EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor

[Term]
id: CHEBI:77105
name: EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor
def: "An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using a cytochrome as acceptor (EC 1.10.2.*)." []
is_a: CHEBI:76737 ! EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor

[Term]
id: CHEBI:77106
name: EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor
def: "An EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor that interferes with the action of quinol—cytochrome-<em>c</em> reductase (EC 1.10.2.2)." []
is_a: CHEBI:77105 ! EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor

[Term]
id: CHEBI:77108
name: EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of 15-hydroxyprostaglandin dehydrogenase (NAD<small><sup>+</small></sup>) (EC 1.1.1.141)." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:77109
name: EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor
def: "An EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.21.3.*)." []
is_a: CHEBI:76748 ! EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor

[Term]
id: CHEBI:77110
name: EC 1.21.3.3 (reticuline oxidase) inhibitor
def: "An EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor that interferes with the action of reticuline oxidase (EC 1.21.3.3, previously EC 1.5.3.9)." []
is_a: CHEBI:77109 ! EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor

[Term]
id: CHEBI:77111
name: EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor
def: "An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of 3'-hydroxy-<em>N</em>-methyl-(<i>S</i>)-coclaurine 4'-<em>O</em>-methyltransferase (EC 2.1.1.116)." []
is_a: CHEBI:76871 ! EC 2.1.1.* (methyltransferases) inhibitor

[Term]
id: CHEBI:77113
name: EC 2.7.11.10 (IkappaB kinase) inhibitor
def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of IκB kinase (EC 2.7.11.10)." []
is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor

[Term]
id: CHEBI:77115
name: EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor
def: "An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (<i>S</i>)-tetrahydroprotoberberine <em>N</em>-methyltransferase (EC 2.1.1.122)." []
is_a: CHEBI:76871 ! EC 2.1.1.* (methyltransferases) inhibitor

[Term]
id: CHEBI:77119
name: EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of prostaglandin-E<small><sub>2</sub></small> 9-reductase (EC 1.1.1.189)." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:77148
name: ginsenoside Re
def: "A ginsenoside found in <em>Panax ginseng</em> that is dammarane which is substituted by hydroxy groups at the 3β, 6α, 12β and 20 <em>pro</em>-<i>S</i> positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding α-<small>L</small>-rhamnopyranosyl-(1→2)-β-<small>D</small>-glucopyranoside and β-<small>D</small>-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position." []
is_a: CHEBI:143563 ! 3beta-hydroxy-4,4-dimethylsteroid
is_a: CHEBI:22798 ! beta-D-glucoside
is_a: CHEBI:26893 ! tetracyclic triterpenoid
is_a: CHEBI:36847 ! 12beta-hydroxy steroid
is_a: CHEBI:63353 ! disaccharide derivative
is_a: CHEBI:74978 ! ginsenoside
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018040 CHEBI:36488 ! has parent hydride dammarane

[Term]
id: CHEBI:77166
name: 3-oxo-Delta(1),Delta(4)-steroid
def: "A 3-oxo-Δ<small><sup>1</small></sup> steroid containing an additional double bond between positions 4 and 5." []
is_a: CHEBI:20156 ! 3-oxo-Delta(1) steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid

[Term]
id: CHEBI:77178
name: histological dye
def: "A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm." []
is_a: CHEBI:37958 ! dye

[Term]
id: CHEBI:77182
name: food colouring
def: "A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199)." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:7719
name: ochratoxin A
def: "A phenylalanine derivative resulting from the formal condensation of the amino group of <small>L</small>-phenylalanine with the carboxy group of (3<i>R</i>)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1<em>H</em>-2-benzopyran-7-carboxylic acid (ochratoxin α). It is among the most widely occurring food-contaminating mycotoxins, produced by <em>Aspergillus ochraceus</em>, <em>Aspergillus carbonarius</em> and <em>Penicillium verrucosum</em>." []
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38762 ! isochromanes
is_a: CHEBI:77673 ! N-acyl-L-phenylalanine
relationship: RO:0000087 CHEBI:25442 ! has role mycotoxin
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:61015 ! has role nephrotoxin
relationship: RO:0000087 CHEBI:76956 ! has role Aspergillus metabolite
relationship: RO:0000087 CHEBI:76964 ! has role Penicillium metabolite
relationship: RO:0018034 CHEBI:166829 ! is protonated form of ochratoxin A(1-)
relationship: RO:0018038 CHEBI:133917 ! has functional parent ochratoxin alpha

[Term]
id: CHEBI:77194
name: EC 2.7.1.33 (pantothenate kinase) inhibitor
def: "An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33)." []
is_a: CHEBI:76881 ! EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor

[Term]
id: CHEBI:77255
name: EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
def: "An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83)." []
is_a: CHEBI:59107 ! EC 3.4.24.* (metalloendopeptidase) inhibitor

[Term]
id: CHEBI:77278
name: 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
def: "An imidazothiazole that is imidazo[2,1-<em>b</em>][1,3]thiazole in which the double bonds at the 2-3 and 5-6 positions have been reduced to single bonds and in which one of the hydrogens at position 6 is replaced by a phenyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48909 ! imidazothiazole
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:77282
name: dexamisole
def: "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-<em>b</em>][1,3]thiazole that has <i>R</i> configuration." []
is_a: CHEBI:77278 ! 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0018039 CHEBI:6432 ! is enantiomer of levamisole

[Term]
id: CHEBI:77307
name: cardioprotective agent
def: "Any protective agent that is able to prevent damage to the heart." []
is_a: CHEBI:50267 ! protective agent

[Term]
id: CHEBI:77308
name: ethylenebis(dithiocarbamate)
def: "A member of the class of dithiocarbamate anions resulting from the deprotonation of both of the dithiocarbamic acid moieties of ethylenebis(dithiocarbamic acid). The major species at pH 7.3." []
is_a: CHEBI:84292 ! dithiocarbamate anions
relationship: RO:0018033 CHEBI:83986 ! is deprotonated form of ethylenebis(dithiocarbamic acid)

[Term]
id: CHEBI:77313
name: rosuvastatin(1-)
def: "A hydroxy monocarboxylic acid anion that is the conjugate base of rosuvastatin, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:36059 ! hydroxy monocarboxylic acid anion
relationship: RO:0018033 CHEBI:38545 ! is deprotonated form of rosuvastatin

[Term]
id: CHEBI:77318
name: pregnane X receptor agonist
def: "An agonist that selectively binds to and activates a pregnane X receptor." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:77326
name: androstane receptor agonist
def: "An agonist that selectively binds to and activates androstane receptors." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:7735
name: olanzapine
def: "A benzodiazepine that is 10<em>H</em>-thieno[2,3-<em>b</em>][1,5]benzodiazepine substituted by a methyl group at position 2 and a 4-methylpiperazin-1-yl group at position 4." []
is_a: CHEBI:22720 ! benzodiazepine
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:46920 ! N-methylpiperazine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37956 ! has role histamine antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:48876 ! has role muscarinic antagonist
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:77383
name: 1,1-bis(phosphonic acid)
def: "Any member of the class of phosphonic acids in which a carbon atom is directly attached to two phosphonic acid groups. They are analogues of pyrophosphates (with the central oxygen atom replaced by a carbon atom) and like pyrophosphates they tend to have a strong affinity for bone, so are frequently used for their antiresorptive and hypocalcaemic properties." []
is_a: CHEBI:26069 ! phosphonic acids

[Term]
id: CHEBI:77397
name: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
def: "A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a <em>p</em>-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:37407 ! cyclic ether
is_a: CHEBI:38831 ! 2-benzofurans
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0018033 CHEBI:77408 ! is deprotonated form of 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium

[Term]
id: CHEBI:77402
name: EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
def: "An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12)." []
is_a: CHEBI:76869 ! EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:77405
name: (R)-citalopram(1+)
def: "A 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-<em>N</em>,<em>N</em>-dimethylpropan-1-aminium resulting from the protonation of the tertiary amino group of (<i>R</i>)-citalopram." []
is_a: CHEBI:77408 ! 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium
relationship: RO:0018034 CHEBI:36792 ! is protonated form of (R)-citalopram
relationship: RO:0018039 CHEBI:77406 ! is enantiomer of escitalopram(1+)

[Term]
id: CHEBI:77406
name: escitalopram(1+)
def: "A 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-<em>N</em>,<em>N</em>-dimethylpropan-1-aminium resulting from the protonation of the tertiary amino group of escitalopram." []
is_a: CHEBI:77408 ! 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium
relationship: RO:0018034 CHEBI:36791 ! is protonated form of escitalopram
relationship: RO:0018039 CHEBI:77405 ! is enantiomer of (R)-citalopram(1+)

[Term]
id: CHEBI:77408
name: 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium
def: "An ammonium ion resulting from the protonation of the tertiary amino group of  1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:77397 ! is protonated form of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile

[Term]
id: CHEBI:77420
name: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide
def: "A hydrobromide resulting from the reaction of equimolar amounts of  1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile and hydrogen bromide." []
is_a: CHEBI:48367 ! hydrobromide
relationship: BFO:0000051 CHEBI:77408 ! has part 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium

[Term]
id: CHEBI:77422
name: (R)-citalopram hydrobromide
def: "A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide resulting from the reaction of equimolar amounts of (<i>R</i>)-citalopram and hydrogen bromide." []
is_a: CHEBI:77420 ! 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide
relationship: RO:0018039 CHEBI:77423 ! is enantiomer of escitalopram hydrobromide

[Term]
id: CHEBI:77423
name: escitalopram hydrobromide
def: "A 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide resulting from the reaction of equimolar amounts of escitalopram and hydrogen bromide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:77420 ! 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0018039 CHEBI:77422 ! is enantiomer of (R)-citalopram hydrobromide

[Term]
id: CHEBI:77425
name: EC 1.1.1.188 (prostaglandin-F synthase) inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of prostaglandin-F synthase (EC 1.1.1.188)." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:77450
name: dicarboxylic acid monoamide(1-)
def: "A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any dicarboxylic acid monoamide; major species at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:35735 ! is deprotonated form of dicarboxylic acid monoamide

[Term]
id: CHEBI:77484
name: EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25)." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:77517
name: 3-methyl-2-butanol
def: "A secondary alcohol that is 2-butanol carrying an additional methyl substituent at position 3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35681 ! secondary alcohol
relationship: RO:0000087 CHEBI:48354 ! has role polar solvent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018040 CHEBI:30362 ! has parent hydride isopentane

[Term]
id: CHEBI:77521
name: thermal degradation product
def: "Any product obtained as a result of thermally induced non-enzymatic degradation." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:77523
name: Maillard reaction product
def: "Any thermal degradation product obtained as a result of a chemical reaction between an amino acid and a reducing sugar (Maillard reaction, a non-enzymatic browning procedure that usually imparts flavour to starch-based food products)." []
is_a: CHEBI:77521 ! thermal degradation product

[Term]
id: CHEBI:77555
name: ent-crizotinib
def: "A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that is the (<i>S</i>)-enantiomer of crizotinib." []
is_a: CHEBI:77562 ! 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
relationship: RO:0018039 CHEBI:64310 ! is enantiomer of crizotinib

[Term]
id: CHEBI:77562
name: 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
def: "A pyrazolylpiperidine that consists of 4-(pyrazol-1-yl)piperidine carrying a 2-amino-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-5-yl group at the 4-position of the pyrazole ring." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38207 ! aminopyridine
is_a: CHEBI:48654 ! pyrazolylpiperidine

[Term]
id: CHEBI:77589
name: monoacyl-sn-glycerol 3-phosphate(2-)
def: "An <em>sn</em>-glycerol 3-phosphate(2−) resulting from partial hydrolysis of a phosphatidate, which removes one of the fatty acid groups." []
is_a: CHEBI:76530 ! sn-glycero-3-monophosphate(2-)
relationship: RO:0018033 CHEBI:17088 ! is deprotonated form of monoacyl-sn-glycerol 3-phosphate

[Term]
id: CHEBI:77608
name: loop diuretic
def: "A diuretic that acts on the ascending loop of Henle in the kidney." []
is_a: CHEBI:35498 ! diuretic

[Term]
id: CHEBI:77615
name: terbinafine(1+)
def: "An organic cation that is the conjugate acid of terbinafine, obtained by protonation of the amino group; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:9448 ! is protonated form of terbinafine

[Term]
id: CHEBI:77654
name: EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor
def: "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> acceptor) inhibitor that interferes with the action of 1-deoxy-<small>D</small>-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267)." []
is_a: CHEBI:76835 ! EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor

[Term]
id: CHEBI:77659
name: emodin(1-)
def: "A phenolate anion that is the conjugate base of emodin, obtained by deprotonation of the phenolic hydroxy group at position 2; major species at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:42223 ! is deprotonated form of emodin

[Term]
id: CHEBI:77672
name: N-acyl-D-phenylalanine
def: "Any <em>N</em>-acyl-<small>D</small>-amino acid obtained by the formal <em>N</em>-acylation of <small>D</small>-phenylalanine." []
is_a: CHEBI:15778 ! N-acyl-D-amino acid
relationship: RO:0018038 CHEBI:16998 ! has functional parent D-phenylalanine
relationship: RO:0018039 CHEBI:77673 ! is enantiomer of N-acyl-L-phenylalanine

[Term]
id: CHEBI:77673
name: N-acyl-L-phenylalanine
def: "Any <em>N</em>-acyl-<small>L</small>-amino acid obtained by the formal <em>N</em>-acylation of <small>L</small>-phenylalanine." []
is_a: CHEBI:21644 ! N-acyl-L-amino acid
is_a: CHEBI:84144 ! L-phenylalanine derivative
relationship: RO:0018039 CHEBI:77672 ! is enantiomer of N-acyl-D-phenylalanine

[Term]
id: CHEBI:77674
name: queuine(1+)
def: "An organic cation that is the conjugate acid of queuine, obtained by protonation of the secondary amino group; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:17433 ! is protonated form of queuine

[Term]
id: CHEBI:77688
name: formononetin(1-)
def: "A flavonoid oxoanion that is the conjugate base of formononetin, obtained by deprotonation of the 7-hydroxy group. Major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:18088 ! is deprotonated form of formononetin

[Term]
id: CHEBI:77699
name: methyl formate
def: "A formate ester resulting from the formal condensation of formic acid with methanol. A low-boiling (31.5 °C) colourless, flammable liquid, it has been used as a fumigant and larvicide for tobacco and food crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:52343 ! formate ester
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:39276 ! has role fumigant
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:78433 ! has role refrigerant

[Term]
id: CHEBI:77700
name: methyl acetate
def: "An acetate ester resulting from the formal condensation of acetic acid with methanol. A low-boiling (57 °C) colourless, flammable liquid, it is used as a solvent for many resins and oils." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:48318 ! has role fragrance
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:77706 ! has role EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor

[Term]
id: CHEBI:77701
name: nitromethane
def: "A primary nitroalkane that is methane in which one of the hydrogens is replace by a nitro group. A polar solvent (b.p. 101 °C), it is an important starting material in organic synthesis. It is also used as a fuel for rockets and radio-controlled models." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133972 ! primary nitroalkane
is_a: CHEBI:134179 ! volatile organic compound
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:63490 ! has role explosive
relationship: RO:0000087 CHEBI:77703 ! has role EC 4.3.1.3 (histidine ammonia-lyase) inhibitor

[Term]
id: CHEBI:77703
name: EC 4.3.1.3 (histidine ammonia-lyase) inhibitor
def: "An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3)." []
is_a: CHEBI:76832 ! EC 4.3.1.* (ammonia-lyase) inhibitor

[Term]
id: CHEBI:77705
name: EC 3.4.19.* (omega-peptidase) inhibitor
def: "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any omega-peptidase (EC 3.4.19.*)." []
is_a: CHEBI:60258 ! EC 3.4.* (hydrolases acting on peptide bond) inhibitor

[Term]
id: CHEBI:77706
name: EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
def: "An EC 3.4.19.* (omega-peptidase) inhibitor that interferes with the action of pyroglutamyl-peptidase I (EC 3.4.19.3)." []
is_a: CHEBI:77705 ! EC 3.4.19.* (omega-peptidase) inhibitor

[Term]
id: CHEBI:77710
name: 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-)
def: "A flavonoid oxoanion obtained by deprotonation of the 5-hydroxy group of 3',4',5-trihydroxy-3,7-dimethoxyflavone. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:18010 ! is deprotonated form of 3',4',5-trihydroxy-3,7-dimethoxyflavone

[Term]
id: CHEBI:77715
name: nasal decongestant
def: "A drug used to relieve nasal congestion in the upper respiratory tract." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:77727
name: delta-lactam
def: "A lactam in which the amide bond is contained within a six-membered ring, which includes the amide nitrogen and the carbonyl carbon." []
is_a: CHEBI:24995 ! lactam

[Term]
id: CHEBI:7773
name: Ondansetron
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48513 ! carbazoles
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:55323 ! has role antidiarrhoeal drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent

[Term]
id: CHEBI:77733
name: 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile
def: "A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:46774 ! polyether
is_a: CHEBI:50996 ! tertiary amino compound

[Term]
id: CHEBI:77734
name: dexverapamil
def: "A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has <i>R</i> configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:77733 ! 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
relationship: RO:0000087 CHEBI:77748 ! has role EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor
relationship: RO:0018033 CHEBI:77737 ! is deprotonated form of dexverapamil(1+)
relationship: RO:0018039 CHEBI:77736 ! is enantiomer of (S)-verapamil

[Term]
id: CHEBI:77736
name: (S)-verapamil
def: "A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has <i>S</i> configuration." []
is_a: CHEBI:77733 ! 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
relationship: RO:0018033 CHEBI:77738 ! is deprotonated form of (S)-verapamil(1+)
relationship: RO:0018039 CHEBI:77734 ! is enantiomer of dexverapamil

[Term]
id: CHEBI:77737
name: dexverapamil(1+)
def: "An ammonium ion resulting from the protonation of the tertiary amino group of dexverapamil." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:77734 ! is protonated form of dexverapamil
relationship: RO:0018039 CHEBI:77738 ! is enantiomer of (S)-verapamil(1+)

[Term]
id: CHEBI:77738
name: (S)-verapamil(1+)
def: "An ammonium ion resulting from the protonation of the tertiary amino group of (<i>S</i>)-verapamil." []
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:77736 ! is protonated form of (S)-verapamil
relationship: RO:0018039 CHEBI:77737 ! is enantiomer of dexverapamil(1+)

[Term]
id: CHEBI:77745
name: EC 3.4.24.18 (meprin A) inhibitor
def: "An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18)." []
is_a: CHEBI:59107 ! EC 3.4.24.* (metalloendopeptidase) inhibitor

[Term]
id: CHEBI:77746
name: human metabolite
def: "Any mammalian metabolite  produced during a metabolic reaction in humans (<em>Homo sapiens</em>)." []
is_a: CHEBI:75768 ! mammalian metabolite

[Term]
id: CHEBI:77747
name: EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor
def: "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1)." []
is_a: CHEBI:76895 ! EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor

[Term]
id: CHEBI:77748
name: EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor
def: "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44)." []
is_a: CHEBI:76895 ! EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor

[Term]
id: CHEBI:77764
name: daidzein(1-)
def: "A flavonoid oxoanion obtained by deprotonation of the 7-hydroxy group of daidzein. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0000087 CHEBI:131699 ! has role EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76989 ! has role phytoestrogen
relationship: RO:0018033 CHEBI:28197 ! is deprotonated form of daidzein

[Term]
id: CHEBI:7778
name: orbencarb
def: "A monothiocarbamic ester that is carbamothioic <i>S</i>-acid substituted by two ethyl groups at the nitrogen atom and a 2-chlorobenzyl group at the the sulfur atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38128 ! monothiocarbamic ester
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:77850
name: toxaphene
def: "A highly complex mixture of several hundred polychlorinated compounds obtained by chlorination of camphene to an overall chlorine content of 67-69% by weight and having an overall empirical formula of C<small><sub>10</sub></small>H<small><sub>10</sub></small>Cl<small><sub>8</sub></small> (including optical isomers, it could theoretically contain over 32,000 congeners). Toxaphene was used from the mid-1940s as an agricultural insecticide (mostly in the USA, particularly on corn and soybeans). Use increased with the phasing out of DDT in the 1970s (it became the most heavily manufactured pesticide in the US) but it is now banned due to concerns about toxicity and carcinogenicity. Total production since its first use is estimated at around 500,000 tons. In the environment, most of the components of toxaphene get metabolised, but from 10 to >100 resist biodegradation, depending on the medium and the specialisation of the enzyme system. Breathing, drinking or eating high levels of toxaphene can damage the lungs, kidneys, and nervous system." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:77853
name: persistent organic pollutant
def: "Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains." []
is_a: CHEBI:78298 ! environmental contaminant

[Term]
id: CHEBI:77860
name: 3-cyano-L-alanine zwitterion
def: "An <small>L</small>-α-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of 3-cyano-<small>L</small>-alanine. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:59869 ! L-alpha-amino acid zwitterion
relationship: RO:0018034 CHEBI:57954 ! is protonated form of 3-cyano-L-alaninate
relationship: RO:0018036 CHEBI:16934 ! is tautomer of 3-cyano-L-alanine

[Term]
id: CHEBI:77881
name: EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
def: "An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of diaminopropionate ammonia-lyase (EC 4.3.1.15)." []
is_a: CHEBI:76832 ! EC 4.3.1.* (ammonia-lyase) inhibitor

[Term]
id: CHEBI:77884
name: EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
def: "An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14α-demethylase)." []
is_a: CHEBI:76841 ! EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor
is_a: CHEBI:83734 ! sterol demethylation inhibitor

[Term]
id: CHEBI:77894
name: aci-nitroethane
def: "An <em>aci</em>-nitro compound that is the predominant form of ethylnitronate at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:136622 ! aci-nitro compound
relationship: RO:0018034 CHEBI:55327 ! is protonated form of aci-nitroethane(1-)
relationship: RO:0018036 CHEBI:16268 ! is tautomer of nitroethane

[Term]
id: CHEBI:77906
name: minocycline zwitterion
def: "A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of minocycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:144644 ! a tetracycline zwitterion
is_a: CHEBI:27369 ! zwitterion
relationship: RO:0018034 CHEBI:71337 ! is protonated form of minocycline(1-)
relationship: RO:0018036 CHEBI:50694 ! is tautomer of minocycline

[Term]
id: CHEBI:77932
name: tetracycline zwitterion
def: "A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of tetracycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:144644 ! a tetracycline zwitterion
is_a: CHEBI:27369 ! zwitterion
relationship: RO:0000087 CHEBI:35820 ! has role antiprotozoal drug
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor
relationship: RO:0018034 CHEBI:71392 ! is protonated form of tetracycline(1-)
relationship: RO:0018036 CHEBI:27902 ! is tautomer of tetracycline

[Term]
id: CHEBI:77941
name: EC 3.5.1.4 (amidase) inhibitor
def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." []
is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor

[Term]
id: CHEBI:77956
name: L-erythro-sphingosine(1+)
def: "A cationic sphingoid resulting from the protonation of the amino group of <small>L</small>-<i>erythro</i>-sphingosine; major species at pH 7.3." []
is_a: CHEBI:83876 ! cationic sphingoid
relationship: RO:0018034 CHEBI:46967 ! is protonated form of L-erythro-sphingosine
relationship: RO:0018039 CHEBI:57756 ! is enantiomer of sphingosine(1+)

[Term]
id: CHEBI:77960
name: food firming agent
def: "A food additive that is used to make or keep fruit or vegetable tissues firm and crisp. or which interacts with gelling agents such as pectin to produce or strengthen a gel." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:77962
name: food antioxidant
def: "An antioxidant that used as a food additives to help guard against food deterioration." []
is_a: CHEBI:22586 ! antioxidant
is_a: CHEBI:65255 ! food preservative

[Term]
id: CHEBI:77964
name: anticaking agent
def: "A substance added to powdered or granulated materials in order to prevent the formation of lumps and so facilitate its packaging or transport." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:77965
name: food anticaking agent
def: "An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another." []
is_a: CHEBI:64047 ! food additive
is_a: CHEBI:77964 ! anticaking agent

[Term]
id: CHEBI:77966
name: food stabiliser
def: "A food additive that is used to preserve the structure of food." []
is_a: CHEBI:64047 ! food additive
is_a: CHEBI:747330 ! stabilizer

[Term]
id: CHEBI:77968
name: humectant
def: "A compound that is used to keep a substance moist." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:77969
name: food humectant
def: "A humectant that is used as a food additive to prevent foodstuffs from drying out." []
is_a: CHEBI:64047 ! food additive
is_a: CHEBI:77968 ! humectant

[Term]
id: CHEBI:77970
name: food thickening agent
def: "A food additive that is used to increase the viscosity of foodstuffs." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:77971
name: raising agent
def: "A food additive which liberates gas so as to increase the volume of a dough or batter, resulting in a lighter and softer finished product." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:77974
name: food packaging gas
def: "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:7798
name: oseltamivir
def: "A cyclohexenecarboxylate ester that is the ethyl ester of oseltamivir acid. An antiviral prodrug (it is hydrolysed to the active free carboxylic acid in the liver), it is used to slow the spread of influenza." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:37529 ! cyclohexenecarboxylate ester
is_a: CHEBI:46668 ! amino-acid ester
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:52425 ! has role EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:33707 ! has functional parent gamma-amino acid

[Term]
id: CHEBI:77981
name: vancomycin aglycone(1-)
def: "A peptide anion that is the conjugate base of vancomycin aglycone and the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:50525 ! phenolate anion
is_a: CHEBI:60334 ! peptide anion
relationship: RO:0018033 CHEBI:47724 ! is deprotonated form of vancomycin aglycone
relationship: RO:0018033 CHEBI:75954 ! is deprotonated form of vancomycin aglycone zwitterion

[Term]
id: CHEBI:78000
name: perindopril(1-)
def: "A monocarboxylic acid anion that is the conjugate base of perindopril, obtained by deprotonation of the hydroxy group; major species at pH 7.3." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:8024 ! is deprotonated form of perindopril

[Term]
id: CHEBI:78003
name: food bleaching agent
def: "A food additive that is used for the purpose of decolourising food." []
is_a: CHEBI:132717 ! bleaching agent
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:78004
name: food bulking agent
def: "A food additive that contributes to the bulk of a food without significantly contributing to its available energy value." []
is_a: CHEBI:64047 ! food additive
is_a: CHEBI:747332 ! filler

[Term]
id: CHEBI:78006
name: food colour retention agent
def: "A food additive that intensifies, retains or stabilises the colour of a food." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:78016
name: food gelling agent
def: "A food additive that enhances the texture of a foodstuff by gel formation." []
is_a: CHEBI:64047 ! food additive

[Term]
id: CHEBI:78017
name: food propellant
def: "A propellant that is used to expel foods from an aerosol container." []
is_a: CHEBI:64047 ! food additive
is_a: CHEBI:76414 ! propellant

[Term]
id: CHEBI:78049
name: octadecenoate
def: "A fatty acid anion containing 18 carbons and one double bond. Formed by deprotonation of the carboxylic acid group. Major species at pH 7.3." []
is_a: CHEBI:82680 ! monounsaturated fatty acid anion
relationship: RO:0018033 CHEBI:25634 ! is deprotonated form of octadecenoic acid

[Term]
id: CHEBI:78060
name: docosahexaenoate
def: "A polyunsaturated fatty acid anion that is the conjugate base of docosahexaenoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:76567 ! polyunsaturated fatty acid anion
relationship: RO:0018033 CHEBI:36005 ! is deprotonated form of docosahexaenoic acid

[Term]
id: CHEBI:78095
name: hexadecenoate
def: "A long-chain unsaturated fatty acid anion that is the conjugate base of hexadecenoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:82680 ! monounsaturated fatty acid anion
relationship: RO:0018033 CHEBI:24548 ! is deprotonated form of hexadecenoic acid

[Term]
id: CHEBI:78113
name: fatty acid anion 3:0
def: "Any saturated fatty acid anion containing 3 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58951 ! short-chain fatty acid anion
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78115
name: fatty acid anion 4:0
def: "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58951 ! short-chain fatty acid anion
is_a: CHEBI:58953 ! saturated fatty acid anion
relationship: RO:0018033 CHEBI:140601 ! is deprotonated form of fatty acid 4:0

[Term]
id: CHEBI:78116
name: fatty acid anion 6:0
def: "Any saturated fatty acid anion containing 6 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion
is_a: CHEBI:59558 ! medium-chain fatty acid anion

[Term]
id: CHEBI:78117
name: fatty acid anion 8:0
def: "Any saturated fatty acid anion containing 8 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78118
name: fatty acid anion 10:0
def: "Any saturated fatty acid anion containing 10 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78119
name: fatty acid anion 12:0
def: "Any saturated fatty acid anion containing 12 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78121
name: fatty acid anion 14:0
def: "Any saturated fatty acid anion containing 14 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78123
name: fatty acid anion 16:0
def: "Any saturated fatty acid anion containing 16 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78125
name: fatty acid anion 18:0
def: "Any saturated fatty acid anion containing 18 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78128
name: fatty acid anion 24:0
def: "Any saturated fatty acid anion containing 24 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." []
is_a: CHEBI:58953 ! saturated fatty acid anion

[Term]
id: CHEBI:78152
name: enzyme mimic
def: "Any small molecule that mimics the action of an enzyme." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:78166
name: 2-lysophosphatidate(2-)
def: "Any monoacylglycerol 3-phosphate(2−) which has a free hydroxy group at the 2-position of the glycerol moiety." []
is_a: CHEBI:78172 ! monoacylglycerol 3-phosphate(2-)
relationship: RO:0018033 CHEBI:76629 ! is deprotonated form of 2-lysophosphatidic acid

[Term]
id: CHEBI:78172
name: monoacylglycerol 3-phosphate(2-)
def: "Any glycero-3-monophosphate carrying a single acyl substituent in an unspecified position (<em>sn</em>-1, <em>sn</em>-2 or <em>sn</em>-3)." []
is_a: CHEBI:78185 ! glycero-3-monophosphate(2-)

[Term]
id: CHEBI:78185
name: glycero-3-monophosphate(2-)
def: "An anionic phospholipid having a phosphate group at <em>sn</em>-1 or <em>sn</em>-3 position of the glycerol backbone, and with a combination of one or two acyl groups, alkyl groups, or alkenyl groups  attached at the <em>sn</em>-1, <em>sn</em>-2, or <em>sn</em>-3 positions through ester, ether or vinyl linkages respectively." []
is_a: CHEBI:62643 ! anionic phospholipid

[Term]
id: CHEBI:78186
name: 1-alkyl-2-acyl-glycero-3-phosphocholine
def: "An alkylacylglycero-3-phosphocholine in which the alkyl and acyl groups are located at positions 1 and 2 respectively. Major species at pH 7.3." []
is_a: CHEBI:78189 ! alkylacylglycero-3-phosphocholine

[Term]
id: CHEBI:78189
name: alkylacylglycero-3-phosphocholine
def: "A glycerophosphocholine that is glycero-3-phosphocholine carrying one alkyl and one acyl group in unspecified positions. Major species at pH 7.3." []
is_a: CHEBI:36313 ! glycerophosphocholine
is_a: CHEBI:64611 ! ether lipid

[Term]
id: CHEBI:7823
name: oxazepam
def: "A 1,4-benzodiazepinone that is 1,3-dihydro-2<em>H</em>-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5." []
is_a: CHEBI:35500 ! 1,4-benzodiazepinone
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:78236
name: N-acetyl-L-cysteinate
def: "A monocarboxylic acid anion that is the conjugate base of  <em>N</em>-acetyl-<small>L</small>-cysteine, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:233443 ! N-acetyl-L-alpha-amino acid anion
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:36044 ! has role antiviral drug
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:74529 ! has role antidote to paracetamol poisoning
relationship: RO:0000087 CHEBI:77034 ! has role mucolytic
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:28939 ! is deprotonated form of N-acetyl-L-cysteine

[Term]
id: CHEBI:7824
name: oxcarbazepine
def: "A dibenzoazepine derivative, having a carbamoyl group at the ring nitrogen, substituted with an oxo group at C-4 of the azepeine ring which is also hydrogenated at C-4 and C-5. It is a anticholinergic anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:47804 ! dibenzoazepine
is_a: CHEBI:53802 ! dibenzooxazepine
relationship: BFO:0000051 CHEBI:23004 ! has part carbamoyl group
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:78240
name: benzoxaborole
def: "Any organic heterobicyclic compound that consists of an oxoborole ring that is <em>ortho</em>-fused to a benzene ring." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38278 ! organoboron compound

[Term]
id: CHEBI:78279
name: lysophosphatidate 18:1
def: "A monoacyl-<em>sn</em>-glycerol 3-phosphate in which the acyl group is specified as octadecenoyl and is attached at either <em>sn</em>-1 or <em>sn</em>-2 position; major species at pH 7.3." []
is_a: CHEBI:77589 ! monoacyl-sn-glycerol 3-phosphate(2-)

[Term]
id: CHEBI:78295
name: food component
def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." []
is_a: CHEBI:52211 ! physiological role

[Term]
id: CHEBI:78298
name: environmental contaminant
def: "Any minor or unwanted substance introduced into the environment that can have undesired effects." []
is_a: CHEBI:51086 ! chemical role

[Term]
id: CHEBI:78299
name: environmental food contaminant
def: "Any unwanted chemical in food. The term includes agrochemicals and industrial chemicals that may contaminate foodstuffs during their production, transportation or storage." []
is_a: CHEBI:78295 ! food component
is_a: CHEBI:78298 ! environmental contaminant

[Term]
id: CHEBI:78320
name: 2-hydroxypropanoic acid
def: "A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the α-hydrogens is replaced by a hydroxy group." []
is_a: CHEBI:49302 ! 2-hydroxy monocarboxylic acid
relationship: RO:0000087 CHEBI:83056 ! has role Daphnia magna metabolite
relationship: RO:0000087 CHEBI:84735 ! has role algal metabolite
relationship: RO:0018034 CHEBI:24996 ! is protonated form of lactate
relationship: RO:0018038 CHEBI:30768 ! has functional parent propionic acid

[Term]
id: CHEBI:78328
name: scutellarein(1-)
def: "A flavonoid oxoanion that is the conjugate base of scutellarein, obtained by selective deprotonation of the 7-hydroxy group. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:60038 ! flavonoid oxoanion
relationship: RO:0018033 CHEBI:9062 ! is deprotonated form of scutellarein

[Term]
id: CHEBI:78337
name: methyl isothiocyanate
def: "An isothiocyanate having a methyl group attached to the nitrogen. It is also the active nematicide of the pronematicide metam-sodium." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:52221 ! isothiocyanate
relationship: RO:0000087 CHEBI:25491 ! has role nematicide
relationship: RO:0000087 CHEBI:39276 ! has role fumigant
relationship: RO:0000087 CHEBI:74136 ! has role lachrymator

[Term]
id: CHEBI:78366
name: EC 2.7.1.1 (hexokinase) inhibitor
def: "An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate." []
is_a: CHEBI:50916 ! lipid kinase inhibitor
is_a: CHEBI:76881 ! EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor

[Term]
id: CHEBI:78420
name: icariin
def: "A member of the class of flavonols that is kaempferol which is substituted at position 8 by a 3-methylbut-2-en-1-yl group and in which the hydroxy groups at positions 3, 4', and 7 have been converted to the corresponding 6-deoxy-α-<small>L</small>-mannopyranoside, methyl ether, and β-D-glucopyranoside, respectively. A phoshphodiesterase-5 inhibitor, it is obtained from several species of plants in the genus <em>Epimedium</em> and is thought to be the main active ingredient of the Chinese herbal medicine Herba Epimedii (yinyanghuo)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:28802 ! flavonols
is_a: CHEBI:50018 ! glycosyloxyflavone
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:71942 ! has role EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor
relationship: RO:0000087 CHEBI:76989 ! has role phytoestrogen

[Term]
id: CHEBI:78433
name: refrigerant
def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:78444
name: EC 3.1.1.1 (carboxylesterase) inhibitor
def: "Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 )." []
is_a: CHEBI:76773 ! EC 3.1.1.* (carboxylic ester hydrolase) inhibitor

[Term]
id: CHEBI:78492
name: diallyl trisulfide
def: "An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity" []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:78493 ! organic trisulfide
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35679 ! has role antilipemic drug
relationship: RO:0000087 CHEBI:35820 ! has role antiprotozoal drug
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:50792 ! has role estrogen receptor antagonist
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:78493
name: organic trisulfide
def: "An organosulfur compound with structure Compounds of structure R<small><sup>1</small></sup>SSSR<small><sup>2</small></sup> in which R<small><sup>1</small></sup> and R<small><sup>2</small></sup> are organic groups." []
is_a: CHEBI:33261 ! organosulfur compound

[Term]
id: CHEBI:78505
name: venom
def: "A toxin used by animals and injected into their victims by a bite or sting." []
is_a: CHEBI:27026 ! toxin

[Term]
id: CHEBI:78523
name: 3,7-bis(dimethylamino)phenothiazine
def: "A member of the class of phenothiazines that is 4a<em>H</em>-phenothiazine substituted by dimethylamino groups at positions 3 and 7." []
is_a: CHEBI:38093 ! phenothiazines
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0018033 CHEBI:43830 ! is deprotonated form of 3,7-bis(dimethylamino)phenothiazin-5-ium
relationship: RO:0018040 CHEBI:37933 ! has parent hydride 4aH-phenothiazine

[Term]
id: CHEBI:78547
name: protein kinase A agonist
def: "A protein kinase agonist that selectively binds to and activates a protein kinase A receptor" []
is_a: CHEBI:64106 ! protein kinase agonist

[Term]
id: CHEBI:78548
name: adenylate cyclase agonist
def: "Any agonist of one or more of the isoforms of adenylate cyclase (EC 4.6.1.1)." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:78592
name: vesicant
def: "Any compound that causes severe skin, eye and mucosal pain and irritation." []
is_a: CHEBI:52208 ! biophysical role

[Term]
id: CHEBI:78604
name: ursodeoxycholate
def: "A bile acid anion that is the conjugate base of ursodeoxycholic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131878 ! cholanic acid anion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:9907 ! is deprotonated form of ursodeoxycholic acid

[Term]
id: CHEBI:78608
name: alpha-amino-acid zwitterion
def: "An amino acid-zwitterion obtained by transfer of a proton from the carboxy to the amino group of any α-amino acid; major species at pH 7.3." []
is_a: CHEBI:35238 ! amino-acid zwitterion
relationship: RO:0018036 CHEBI:33704 ! is tautomer of alpha-amino acid

[Term]
id: CHEBI:78616
name: carbohydrates and carbohydrate derivatives
def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula C<small><sub><em>m</em></sub></small>(H<small><sub>2</sub></small>O)<small><sub><em>n</em></sub></small>; carbohydrate derivatives may contain other elements by substitution or condensation." []
is_a: CHEBI:36963 ! organooxygen compound

[Term]
id: CHEBI:78630
name: 9-cis-retinoate
def: "A retinoate that is the conjugate base of 9-<i>cis</i>-retinoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:15036 ! retinoate
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50176 ! has role keratolytic drug
relationship: RO:0000087 CHEBI:63794 ! has role retinoid X receptor agonist
relationship: RO:0018033 CHEBI:50648 ! is deprotonated form of 9-cis-retinoic acid

[Term]
id: CHEBI:78631
name: chroman-6-ol
def: "A chromanol that is chromane in which the hydrogen at position 6 is replaced by a hydroxy group." []
is_a: CHEBI:23229 ! chromanol
is_a: CHEBI:33853 ! phenols
relationship: RO:0018040 CHEBI:33224 ! has parent hydride chromane

[Term]
id: CHEBI:78673
name: cumene hydroperoxide
def: "A peroxol that is cumene in which the α-hydrogen is replaced by a hydroperoxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35924 ! peroxol
relationship: RO:0000087 CHEBI:131604 ! has role Mycoplasma genitalium metabolite
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018040 CHEBI:34656 ! has parent hydride cumene

[Term]
id: CHEBI:78675
name: fundamental metabolite
def: "Any metabolite produced by all living cells." []
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:78678
name: EC 4.6.1.2 (guanylate cyclase) inhibitor
def: "An EC 4.6.* (<em>P</em>‒<em>O</em> lyase) inhibitor that interferes with the action of enzyme guanylate cyclase (EC 4.6.1.2)." []
is_a: CHEBI:76716 ! EC 4.6.* (P-O lyase) inhibitor

[Term]
id: CHEBI:78741
name: oxidopamine
def: "A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease)." []
is_a: CHEBI:22707 ! benzenetriol
is_a: CHEBI:33567 ! catecholamine
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0018038 CHEBI:18243 ! has functional parent dopamine

[Term]
id: CHEBI:78763
name: EC 2.7.11.18 (myosin-light-chain kinase) inhibitor
def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of myosin-light-chain kinase (EC 2.7.11.18)." []
is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor

[Term]
id: CHEBI:78780
name: pyraclostrobin
def: "A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1<em>H</em>-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including <em>Septoria tritici</em>, <em>Puccinia</em> spp. and <em>Pyrenophora teres</em>." []
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:86485 ! methoxycarbanilate strobilurin antifungal agent
is_a: CHEBI:87066 ! carbanilate fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38499 ! has role mitochondrial cytochrome-bc1 complex inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:78787
name: dithiocarbamic acids
def: "Any organic acid in which both oxygens of a carbamic acid have been replaced by sulfur." []
is_a: CHEBI:35352 ! organonitrogen compound
is_a: CHEBI:50492 ! thiocarbonyl compound
is_a: CHEBI:64709 ! organic acid
relationship: RO:0018034 CHEBI:84292 ! is protonated form of dithiocarbamate anions

[Term]
id: CHEBI:78802
name: diarylheptanoid
def: "A family of plant metabolites with a common 1,7-diphenylheptane structural skeleton, carrying various substituents. They are mainly distributed in the roots, rhizomes and bark of <em>Alpinia, Zingiber, Curcuma</em> and <em>Alnus</em> species." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:33836 ! benzenoid aromatic compound
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:78803
name: nematode metabolite
def: "An animal metabolite produced by any member of the phylum Nematoda." []
is_a: CHEBI:75767 ! animal metabolite

[Term]
id: CHEBI:78804
name: Caenorhabditis elegans metabolite
def: "A nematode metabolite produced by <em>Caenorhabditis elegans</em>." []
is_a: CHEBI:78803 ! nematode metabolite

[Term]
id: CHEBI:78840
name: olefinic compound
def: "Any organic molecular entity that contains at least one C=C bond." []
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:78870
name: sodium nitrite
def: "An inorganic sodium salt having nitrite as the counterion. Used as a food preservative and antidote to cyanide poisoning." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38702 ! inorganic sodium salt
is_a: CHEBI:46648 ! nitrite salt
is_a: CHEBI:50860 ! organic molecular entity
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:64909 ! has role poison
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:65256 ! has role antimicrobial food preservative
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77962 ! has role food antioxidant
relationship: RO:0000087 CHEBI:90749 ! has role antidote to cyanide poisoning

[Term]
id: CHEBI:78887
name: tirapazamine
def: "A member of the class of benzotriazines that is 1,2,4-benzotriazine carrying an amino substituent at position 3 and two oxido substituents at positions 1 and 4." []
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35580 ! N-oxide
is_a: CHEBI:39410 ! 1,2,4-triazines
is_a: CHEBI:51361 ! benzotriazines
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0018038 CHEBI:38011 ! has functional parent 1,2,4-benzotriazine

[Term]
id: CHEBI:78897
name: trypan blue
def: "An organosulfonate salt that is the tetrasodium salt of 3,3'-[(3,3'-dimethylbiphenyl-4,4'-diyl)didiazene-2,1-diyl]bis(5-amino-4-hydroxynaphthalene-2,7-disulfonic acid)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36336 ! naphthalenesulfonic acid
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:64382 ! organosulfonate salt
relationship: BFO:0000051 CHEBI:78899 ! has part trypan blue(4-)
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:77178 ! has role histological dye

[Term]
id: CHEBI:78899
name: trypan blue(4-)
def: "An organosulfonate oxoanion that is the tetraanionic form of trypan blue." []
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:78900 ! is deprotonated form of trypan blue sulfonic acid

[Term]
id: CHEBI:78900
name: trypan blue sulfonic acid
def: "An aminonaphthalenesulfonic acid that is the free acid form of trypan blue dye." []
is_a: CHEBI:22682 ! azobenzenes
is_a: CHEBI:25392 ! naphthols
is_a: CHEBI:38210 ! aminonaphthalenesulfonic acid
relationship: RO:0000087 CHEBI:37958 ! has role dye
relationship: RO:0018034 CHEBI:78899 ! is protonated form of trypan blue(4-)

[Term]
id: CHEBI:78902
name: L-canavanine(1+)
def: "An α-amino-acid cation that is the conjugate acid of <small>L</small>-canavanine; major species at pH 7.3." []
is_a: CHEBI:33719 ! alpha-amino-acid cation
relationship: RO:0018034 CHEBI:405237 ! is protonated form of L-canavanine zwitterion
relationship: RO:0018034 CHEBI:609827 ! is protonated form of L-canavanine

[Term]
id: CHEBI:7896
name: hexadecanoate
def: "A long-chain fatty acid anion that is the conjugate base of hexadecanoic acid (palmitic acid); major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:57560 ! long-chain fatty acid anion
is_a: CHEBI:76619 ! omega-methyl fatty acid anion
is_a: CHEBI:78123 ! fatty acid anion 16:0
is_a: CHEBI:83955 ! 2-saturated fatty acid anion
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:15756 ! is deprotonated form of hexadecanoic acid

[Term]
id: CHEBI:79008
name: (R)-nicotinium(1+)
def: "The conjugate acid of (<i>R</i>)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:39162 ! is protonated form of (R)-nicotine
relationship: RO:0018039 CHEBI:59806 ! is enantiomer of (S)-nicotinium(1+)

[Term]
id: CHEBI:79020
name: alpha,beta-unsaturated monocarboxylic acid
def: "A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C≡C bond." []
is_a: CHEBI:25384 ! monocarboxylic acid

[Term]
id: CHEBI:79056
name: plasticiser
def: "Any compound that is used as an additive to increase the plasticity or fluidity of a substance, particularly but not exclusively to synthetic polymers." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:79091
name: EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24)." []
is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor

[Term]
id: CHEBI:7915
name: pantoprazole
def: "A member of the class of  benzimidazoles that is 1<em>H</em>-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22063 ! sulfoxide
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:49200 ! has role EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:50358 ! is protonated form of pantoprazole(1-)

[Term]
id: CHEBI:7916
name: pantothenic acid
def: "A member of the class of pantothenic acids that is an amide formed from pantoic acid and β-alanine." []
is_a: CHEBI:25848 ! pantothenic acids
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:16454 ! is protonated form of pantothenate

[Term]
id: CHEBI:79313
name: glycosinolic acid
def: "An organic sulfate that is the oxime hydrogen sulfate of an <em>S</em>-acyl thioglycoside." []
is_a: CHEBI:25704 ! organic sulfate
is_a: CHEBI:35275 ! S-glycosyl compound
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0018034 CHEBI:24401 ! is protonated form of glycosinolate

[Term]
id: CHEBI:79314
name: flame retardant
def: "Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire." []
is_a: CHEBI:33232 ! application

[Term]
id: CHEBI:79316
name: glucosinolic acid
def: "A glycosinolic acid derived from glucose. Glucosinolic acids have a central C atom which is bonded via an S atom to a glucosyl group and via an N atom to a sulfonated oxime group, and which also carries a side-group. The side-chain and sulfate group have an <i>anti</i> stereochemical configuration across the C=N double bond." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:136440 ! beta-D-thioglucoside
is_a: CHEBI:79313 ! glycosinolic acid
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018034 CHEBI:24279 ! is protonated form of glucosinolate
relationship: RO:0018038 CHEBI:136442 ! has functional parent desulfoglucosinolic acid

[Term]
id: CHEBI:79323
name: 4-hydroxybenzoate ester
def: "A benzoate ester that is an ester of 4-hydroxybenzoic acid." []
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:36054 ! benzoate ester
relationship: RO:0018038 CHEBI:30763 ! has functional parent 4-hydroxybenzoic acid

[Term]
id: CHEBI:7936
name: paroxetine
def: "A benzodioxole that consists of piperidine bearing 1,3-benzodioxol-5-yloxy)methyl and 4-fluorophenyl substituents at positions 3 and 4 respectively; the (3<i>S</i>,4<i>R</i>)-diastereomer. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for α1-, α2- or β-adrenoceptors, 5-HT<small><sub>2A</sub></small>, 5-HT<small><sub>1A</sub></small>, D<small><sub>2</sub></small> or H<small><sub>1</sub></small> receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38298 ! benzodioxoles
is_a: CHEBI:83575 ! monofluorobenzenes
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:50183 ! has role P450 inhibitor
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0018033 CHEBI:64197 ! is deprotonated form of paroxetinium(1+)

[Term]
id: CHEBI:79387
name: trivalent inorganic anion
def: "Any inorganic anion with a valency of three." []
is_a: CHEBI:24834 ! inorganic anion

[Term]
id: CHEBI:79388
name: divalent inorganic anion
def: "Any inorganic anion with a valency of two." []
is_a: CHEBI:24834 ! inorganic anion

[Term]
id: CHEBI:79389
name: monovalent inorganic anion
def: "Any inorganic anion with a valency of one." []
is_a: CHEBI:24834 ! inorganic anion

[Term]
id: CHEBI:79395
name: willow bark extract
def: "A mixture resulting from extraction of the bark (also leaves) of any member of the genus <em>Salix</em>. The main active ingredient is salicin." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:17814 ! has part salicin
relationship: BFO:0000051 CHEBI:26267 ! has part proanthocyanidin
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic

[Term]
id: CHEBI:79401
name: vincristine sulfate
def: "An organic sulfate salt containing equimolar amounts of vincristine(2+) and sulfate. Used for the treatment of a variety of cancers." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:51337 ! organic sulfate salt
relationship: BFO:0000051 CHEBI:143658 ! has part vincristine(2+)
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:79516
name: Nonylphenol
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:7983
name: pentobarbital
def: "A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and <em>sec</em>-pentyl groups." []
is_a: CHEBI:22693 ! barbiturates
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:91016 ! has role GABAA receptor agonist

[Term]
id: CHEBI:7984
name: Pentobarbital sodium
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate

[Term]
id: CHEBI:79932
name: Flurogestone acetate
is_a: CHEBI:36699 ! corticosteroid hormone

[Term]
id: CHEBI:8005
name: peptidoglycan
def: "A peptidoglycosaminoglycan formed by alternating residues of β-(1→4)-linked <em>N</em>-acetylglucosamine and <em>N</em>-acetylmuramic acid {2-amino-3-<em>O</em>-[(<i>S</i>)-1-carboxyethyl]-2-deoxy-<small>D</small>-glucose} residues. Attached to the carboxy group of the muramic acid is a peptide chain of three to five amino acids." []
is_a: CHEBI:86469 ! peptidoglycosaminoglycan

[Term]
id: CHEBI:8024
name: perindopril
def: "An α-amino acid ester that is the ethyl ester of <em>N</em>-{(2<i>S</i>)-1-[(2<i>S</i>,3a<i>S</i>,7a<i>S</i>)-2-carboxyoctahydro-1<em>H</em>-indol-1-yl]-1-oxopropan-2-yl}-<small>L</small>-norvaline" []
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:36244 ! dicarboxylic acid monoester
is_a: CHEBI:46761 ! dipeptide
is_a: CHEBI:46874 ! alpha-amino acid ester
relationship: RO:0000087 CHEBI:35457 ! has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0018034 CHEBI:78000 ! is protonated form of perindopril(1-)

[Term]
id: CHEBI:8028
name: perphenazine
def: "A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:38093 ! phenothiazines
is_a: CHEBI:46851 ! N-(2-hydroxyethyl)piperazine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:37930 ! has role phenothiazine antipsychotic drug
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0018040 CHEBI:37931 ! has parent hydride 10H-phenothiazine

[Term]
id: CHEBI:80291
name: aliphatic nitrile
def: "Any nitrile derived from an aliphatic compound." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:33653 ! aliphatic compound

[Term]
id: CHEBI:80308
name: substance P
def: "A neuropeptide consisting of 11-amino acids. It preferentially activates neurokinin-1 receptors, exterting excitatory effects on central and peripheral neurons and involved in pain transmission." []
is_a: CHEBI:16670 ! peptide
relationship: RO:0000087 CHEBI:194137 ! has role neurokinin-1 receptor agonist
relationship: RO:0000087 CHEBI:25512 ! has role neurotransmitter
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0018033 CHEBI:190692 ! is deprotonated form of substance P(3+)

[Term]
id: CHEBI:80495
name: benzidine
def: "A member of the class of biphenyls that is 1,1'-biphenyl in which the hydrogen at the <em>para</em>-position of each phenyl group has been replaced by an amino group." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:48975 ! substituted aniline
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:80501
name: Coal-tar pitch
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:8058
name: phencyclidine
def: "A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group.  Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:32952 ! amine
relationship: RO:0000087 CHEBI:35471 ! has role psychotropic drug
relationship: RO:0000087 CHEBI:38867 ! has role anaesthetic
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0018040 CHEBI:18049 ! has parent hydride piperidine

[Term]
id: CHEBI:80630
name: irinotecan
def: "A member of the class of pyranoindolizinoquinolines that is the carbamate ester obtained by formal condensation of the carboxy group of [1,4'-bipiperidine]-1'-carboxylic acid with the phenolic hydroxy group of (4<i>S</i>)-4,11-diethyl-4,9-dihydroxy-1<em>H</em>-pyrano[3',4':6,7]indolizino[1,2- hydrochloride]quinoline-3,14-dione. Used (in the form of its hydrochloride salt trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active." []
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:36820 ! ring assembly
is_a: CHEBI:48591 ! N-acylpiperidine
is_a: CHEBI:48626 ! pyranoindolizinoquinoline
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50276 ! has role EC 5.99.1.2 (DNA topoisomerase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0018033 CHEBI:90895 ! is deprotonated form of irinotecan(1+)
relationship: RO:0018038 CHEBI:8988 ! has functional parent SN-38

[Term]
id: CHEBI:8069
name: phenobarbital
def: "A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups." []
synonym: "5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione" EXACT [ChEMBL]
is_a: CHEBI:22693 ! barbiturates
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35717 ! has role sedative
relationship: RO:0000087 CHEBI:60798 ! has role excitatory amino acid antagonist
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:80690
name: Thyroglobulin triiodothyronine
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:80730
name: Coronatine
is_a: CHEBI:51569 ! N-acyl-amino acid

[Term]
id: CHEBI:8075
name: phenoxyacetic acid
def: "A monocarboxylic acid that is the <em>O</em>-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:35219 ! has role plant growth retardant
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:76956 ! has role Aspergillus metabolite
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0018034 CHEBI:38846 ! is protonated form of phenoxyacetate
relationship: RO:0018038 CHEBI:17497 ! has functional parent glycolic acid

[Term]
id: CHEBI:80774
name: tauroursodeoxycholic acid
def: "A bile acid taurine conjugate derived from ursoodeoxycholic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23219 ! bile acid taurine conjugate
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:68494 ! has role apoptosis inhibitor
relationship: RO:0000087 CHEBI:77307 ! has role cardioprotective agent
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:132028 ! is protonated form of tauroursodeoxycholate
relationship: RO:0018038 CHEBI:9907 ! has functional parent ursodeoxycholic acid

[Term]
id: CHEBI:80793
name: Arctiin
is_a: CHEBI:24400 ! glycoside
is_a: CHEBI:25036 ! lignan

[Term]
id: CHEBI:80795
name: Atractylodin
is_a: CHEBI:24129 ! furans

[Term]
id: CHEBI:8092
name: 1,3-phenylenediamine
def: "A  phenylenediamine  taht is benzene substituted at positions 1 and 3 with amino functions." []
is_a: CHEBI:51402 ! phenylenediamine

[Term]
id: CHEBI:8093
name: phenylephrine
def: "A member of the class of the class of phenylethanolamines that is (1<i>R</i>)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring." []
is_a: CHEBI:25990 ! phenylethanolamines
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35524 ! has role sympathomimetic agent
relationship: RO:0000087 CHEBI:35569 ! has role alpha-adrenergic agonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38147 ! has role cardiotonic drug
relationship: RO:0000087 CHEBI:50267 ! has role protective agent
relationship: RO:0000087 CHEBI:50513 ! has role mydriatic agent
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0018033 CHEBI:132294 ! is deprotonated form of phenylephrine(1+)

[Term]
id: CHEBI:81068
name: Shikonin
is_a: CHEBI:132157 ! hydroxy-1,4-naphthoquinone

[Term]
id: CHEBI:8107
name: phenytoin
def: "A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5." []
synonym: "5,5-diphenylimidazolidine-2,4-dione" EXACT [ChEMBL]
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24628 ! imidazolidine-2,4-dione
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:38633 ! has role sodium channel blocker
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:27612 ! has functional parent hydantoin

[Term]
id: CHEBI:8116
name: phorbol
def: "A diterpenoid with the structure of tigliane hydroxylated at C-4, -9, -12(β), -13 and -20, with an oxo group at C-3 and unsaturation at the 1- and 6-positions." []
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:51689 ! enone
is_a: CHEBI:52557 ! tetracyclic diterpenoid
relationship: RO:0018040 CHEBI:37526 ! has parent hydride tigliane

[Term]
id: CHEBI:81217
name: chrysanthemol
is_a: CHEBI:134362 ! homoallylic alcohol
is_a: CHEBI:15734 ! primary alcohol
is_a: CHEBI:25409 ! monoterpenoid
is_a: CHEBI:51454 ! cyclopropanes

[Term]
id: CHEBI:81244
name: hyocholic acid
def: "A trihydroxy-5β-cholanic acid in which the three hydroxy substituents are located at the 3α-, 6α- and 7α-positions." []
is_a: CHEBI:134216 ! muricholic acids
is_a: CHEBI:36843 ! 7alpha-hydroxy steroid
is_a: CHEBI:36850 ! 6alpha-hydroxy steroid
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0000087 CHEBI:86264 ! has role rat metabolite
relationship: RO:0018034 CHEBI:133661 ! is protonated form of hyocholate

[Term]
id: CHEBI:81278
name: 4-(4-Hydroxyphenyl)-2-butanol
is_a: CHEBI:33853 ! phenols

[Term]
id: CHEBI:81364
name: Dioxation
is_a: CHEBI:46926 ! dioxanes
is_a: CHEBI:60911 ! racemate

[Term]
id: CHEBI:81502
name: 1,2,3,4,7,8-Hexachlorodibenzodioxin
is_a: CHEBI:36682 ! polychlorinated dibenzodioxine

[Term]
id: CHEBI:81503
name: 1,2,3,6,7,8-Hexachlorodibenzodioxin
is_a: CHEBI:36682 ! polychlorinated dibenzodioxine

[Term]
id: CHEBI:81505
name: 1,2,3,4,6,7,8-Heptachlorodibenzodioxin
is_a: CHEBI:36682 ! polychlorinated dibenzodioxine

[Term]
id: CHEBI:81506
name: 2,3,7,8-Tetrachlorodibenzofuran
is_a: CHEBI:134046 ! polychlorinated dibenzofuran

[Term]
id: CHEBI:81513
name: 1,2,3,4,6,7,8-Heptachlorodibenzofuran
is_a: CHEBI:134046 ! polychlorinated dibenzofuran

[Term]
id: CHEBI:81516
name: 3,4,4',5-Tetrachlorobiphenyl
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36720 ! tetrachlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:81517
name: 3,4,5,3',4',5'-Hexachlorobiphenyl
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:81518
name: 2,3,4,3',4'-Pentachlorobiphenyl
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36721 ! pentachlorobiphenyl

[Term]
id: CHEBI:81519
name: 2,3,4,4',5-Pentachlorobiphenyl
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:36721 ! pentachlorobiphenyl
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:81520
name: 2,3',4,4',5-Pentachlorobiphenyl
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36721 ! pentachlorobiphenyl

[Term]
id: CHEBI:81521
name: 2,3',4,4',5'-Pentachlorobiphenyl
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36721 ! pentachlorobiphenyl

[Term]
id: CHEBI:81522
name: 2,3,3',4,4',5-Hexachlorobiphenyl
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:81523
name: 2,3,3',4,4',5'-Hexachlorobiphenyl
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:81524
name: 2,3',4,4',5,5'-Hexachlorobiphenyl
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:36722 ! hexachlorobiphenyl

[Term]
id: CHEBI:81525
name: 2,3,3',4,4',5,5'-Heptachlorobiphenyl
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:85782 ! heptachlorobiphenyl

[Term]
id: CHEBI:81534
name: 2,2',4,4',5,5'-Hexabromodiphenyl ether
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:81535
name: 2,2',4,4',5,6'-Hexabromodiphenyl ether
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:81537
name: 2,2',3,4,4',5',6-Heptabromodiphenyl ether
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:81539
name: metiram
def: "A polymer comprising ethylenebis(dithiocarbamate) units and (ammonia)zinc(II). It is used in agriculture for the control of scab in fruit, blight in tomatoes and potatoes, and downy mildew in hops and grapes." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60027 ! polymer
relationship: BFO:0000051 CHEBI:36566 ! has part zinc coordination entity
relationship: BFO:0000051 CHEBI:83060 ! has part dithiocarbamate salt
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81542
name: Octachlorostyrene
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:81555
name: Enterolactone
is_a: CHEBI:25036 ! lignan

[Term]
id: CHEBI:81556
name: Enterodiol
is_a: CHEBI:25036 ! lignan

[Term]
id: CHEBI:81567
name: thyroid stimulating hormone
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17089 ! glycoprotein
relationship: RO:0000087 CHEBI:24621 ! has role hormone

[Term]
id: CHEBI:81568
name: Luteinizing hormone
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:17089 ! glycoprotein
relationship: RO:0000087 CHEBI:24621 ! has role hormone

[Term]
id: CHEBI:81582
name: 2,4-dibromophenyl 2,4,5-tribromophenyl ether
def: "A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, 5, 2', and 4' positions have been replaced by bromines." []
is_a: CHEBI:134094 ! polybromodiphenyl ether

[Term]
id: CHEBI:81584
name: 2,2',4,4'-Tetrabromodiphenyl ether
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37141 ! organobromine compound

[Term]
id: CHEBI:81599
name: 1,1-Dichloroethane
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:81667
name: 2-hydroxy-5-methylquinone
def: "A member of the class of monohydroxy-1,4-benzoquinones that is 2-hydroxy-1,4-benzoquinone carrying an additional methyl substituent at position 5." []
is_a: CHEBI:67273 ! monohydroxy-1,4-benzoquinones
relationship: RO:0018034 CHEBI:88190 ! is protonated form of 2-oxido-5-methylquinone

[Term]
id: CHEBI:81696
name: asulam
def: "A carbamate ester that is methyl carbamate substituted by a (4-aminophenyl)sulfonyl group at the nitrogen atom. A dihydropteroate synthase inhibitor, it is used (normally as the corresponding sodium salt, asulam-sodium) as a herbicide, mainly for killing bracken." []
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50502 ! has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:142669 ! is protonated form of asulam(1-)

[Term]
id: CHEBI:81728
name: Anilofos
is_a: CHEBI:13248 ! anilide

[Term]
id: CHEBI:81733
name: desmedipham
def: "A carbamate ester that is phenylcarbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(ethoxycarbonyl)amino]phenyl group. It is an agrochemical used as a herbicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:52496 ! has functional parent phenylcarbamic acid

[Term]
id: CHEBI:81734
name: phenmedipham
def: "A carbamate ester that is (3-methylphenyl)carbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(methoxycarbonyl)amino]phenyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81758
name: cyproconazole
def: "A diastereoisomeric mixture composed of the enantiomeric pair (2<i>R</i>,3<i>S</i>)- and (2<i>S</i>,3<i>R</i>)-cyproconazole in ratio 1:1 with the enantiomeric pair (2<i>R</i>,3<i>R</i>)- and (2<i>S</i>,3<i>S</i>)-cyproconazole. A broad spectrum fungicide, it is used on cereals and other field crops used to control Septoria, rust, powdery mildew and other diseases." []
is_a: CHEBI:60915 ! diastereoisomeric mixture
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: BFO:0000051 CHEBI:83749 ! has part (2R,3S)-cyproconazole
relationship: BFO:0000051 CHEBI:83750 ! has part (2S,3S)-cyproconazole
relationship: BFO:0000051 CHEBI:83752 ! has part (2S,3R)-cyproconazole
relationship: BFO:0000051 CHEBI:83753 ! has part (2R,3R)-cyproconazole
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50908 ! has role hepatotoxic agent
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81760
name: difenoconazole
def: "A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups.  A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms." []
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:39430 ! dioxolane
is_a: CHEBI:59779 ! cyclic ketal
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81773
name: metconazole
def: "A member of the class of cyclopentanols carrying 1,2,4-triazol-1-ylmethyl and 4-chlorobenzyl and geminal dimethyl substituents at positions 1, 2 and 5 respectively. Used to control a range of fungal infections including alternaria, rusts, fusarium and septoria diseases." []
is_a: CHEBI:23495 ! cyclopentanols
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81781
name: tebuconazole
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: BFO:0000051 CHEBI:83780 ! has part (S)-tebuconazole
relationship: BFO:0000051 CHEBI:83781 ! has part (R)-tebuconazole
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81788
name: cymoxanil
def: "A member of the class of ureas that is urea in which the two nitrogen atoms are substituted by an ethyl group and a 2-cyano-2-(methoxyimino)acetyl group respectively. A fungicide used to control <em>Peronosporales</em> on a range of crops including vines, hops and potatoes." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:36816 ! oxime O-ether
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:86417 ! aliphatic nitrogen antifungal agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81789
name: dimethenamid
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-dimethenamid. A herbicide, it is applied to the soil for the control of various broad-leaved weeds and grasses. Only the <i>S</i> enantiomer (generally known as dimethenamid-P) is active." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83639 ! has part (R)-dimethenamid
relationship: BFO:0000051 CHEBI:83640 ! has part dimethenamid-P
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:64911 ! has role antimitotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81805
name: fluazifop
def: "A racemate comprising equimolar amounts of (<i>R</i>)-fluazipop (the active enantiomer, also known as fluazifop-P) and (<i>S</i>)-fluazifop (the inactive enantiomer). Both fluazifop and fluazifop-P have been used (generally as the corresponidng n-butyl esters, known as fluazifop-butyl and fluazifop-P-butyl, respectively) as herbicides for the pre-emergence control of grass weeds in a variety of crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83599 ! has part fluazifop-P
relationship: BFO:0000051 CHEBI:83600 ! has part (S)-fluazifop
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81806
name: 2-methyl-4-chlorophenoxybutyric acid
def: "A monocarboxylic acid that is butyric acid substituted by a 2-methyl-4-chlorophenoxy group at position 4." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81807
name: quizalofop-ethyl
def: "A racemate coprising equimolar amounts of  quizalofop-P-ethyl and its enantiomer, (<i>S</i>)-quizalofop-ethyl. A proherbicide for quizalofop." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:137938 ! has part quizalofop-P-ethyl
relationship: BFO:0000051 CHEBI:137939 ! has part (S)-quizalofop-ethyl
relationship: RO:0000087 CHEBI:136646 ! has role proherbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:81815
name: Sethoxydim
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:81817
name: trinexapac-ethyl
def: "An ethyl ester resulting from the formal condensation of the carboxy group of trinexapac with ethanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23482 ! cyclohexanones
is_a: CHEBI:23990 ! ethyl ester
is_a: CHEBI:33823 ! enol
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:55380 ! beta-hydroxy ketone
relationship: RO:0000087 CHEBI:136859 ! has role pro-agent
relationship: RO:0000087 CHEBI:26155 ! has role plant growth regulator
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:73193 ! has role gibberellin biosynthesis inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:83454 ! has functional parent trinexapac

[Term]
id: CHEBI:81821
name: ioxynil
def: "A  nitrile that is benzonitrile substituted by a hydroxy group at position 4 and iodo groups at positions 3 and 5." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:24863 ! iodophenol
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81822
name: boscalid
def: "A pyridinecarboxamide obtained by formal condensation of the carboxy group of 2-chloronicotinic acid with the amino group of 4'-chlorobiphenyl-2-amine. A fungicide active against a broad range of fungal pathogens including <em>Botrytis</em> spp., <em>Alternaria</em> spp. and <em>Sclerotinia</em> spp. for use on a wide range of crops including fruit, vegetables and ornamentals." []
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:25529 ! pyridinecarboxamide
is_a: CHEBI:62733 ! aromatic amide
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:87015 ! anilide fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:83072 ! has role EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:15940 ! has functional parent nicotinic acid

[Term]
id: CHEBI:81824
name: diflufenican
def: "A pyridinecarboxamide that is pyridine-3-carboxamide substituted by a 2,4-difluorophenyl group at the carbamoyl nitrogen and a 3-(trifluoromethyl)phenoxy group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25529 ! pyridinecarboxamide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:138208 ! has role carotenoid biosynthesis inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81838
name: chloridazon
def: "A pyridazinone that is pyridazin-3(2<em>H</em>)-one substituted by an amino group at position 5, a chloro group at position 4 and a phenyl group at position 2." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:26414 ! pyridazinone
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81843
name: fluazinam
def: "A member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens." []
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:38207 ! aminopyridine
is_a: CHEBI:39173 ! chloropyridine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81848
name: dimethomorph
def: "A mixture of (<i>E</i>)- and (<i>Z</i>)-dimethomorph in an unspecified ratio. It is used as a systemic fungicide used on vines, potatoes, and greenhouse crops; only the <i>Z</i> isomer has fungicidal activity." []
is_a: CHEBI:60004 ! mixture
is_a: CHEBI:87134 ! morpholine fungicide
relationship: BFO:0000051 CHEBI:83426 ! has part (E)-dimethomorph
relationship: BFO:0000051 CHEBI:83427 ! has part (Z)-dimethomorph
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81856
name: dicamba
def: "A methoxybenzoic acid that is <em>O</em>-methylsalicylic acid substituted by chloro groups at positions 3 and 6." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:25238 ! methoxybenzoic acid
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:141349 ! is protonated form of 3,6-dichloro-2-methoxybenzoate

[Term]
id: CHEBI:81857
name: imazamox
def: "A racemate composed of equimolar amounts of (<i>S</i>)- and (<i>R</i>)-imazamox. An inhibitor of acetohydroxyacid synthase, it is used (particularly as the corresponding ammonium salt, known as imazamox-ammonium) as a herbicide for the control of grass, broad-leaf weeds, and pond weed." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83743 ! has part (S)-imazamox
relationship: BFO:0000051 CHEBI:83744 ! has part (R)-imazamox
relationship: RO:0000087 CHEBI:22180 ! has role EC 2.2.1.6 (acetolactate synthase) inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81859
name: Dalapon
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:33575 ! carboxylic acid

[Term]
id: CHEBI:81883
name: Dinoterb
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35716 ! C-nitro compound

[Term]
id: CHEBI:81909
name: diclofop
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-diclofop. It is a metabolite of declofop-methyl and a postemergence herbicide used for the control of wild oats and annual weeds in wheat, barley, rye and broad-leaved crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:145403 ! has part (R)-diclofop
relationship: BFO:0000051 CHEBI:145404 ! has part (S)-diclofop
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide

[Term]
id: CHEBI:81911
name: dimethachlor
def: "An organochlorine compound that is 2-chloroacetamide substituted by a 2-methoxyethyl and a 2,6-dimethylphenyl group at the nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81912
name: Dimethipin
is_a: CHEBI:35850 ! sulfone

[Term]
id: CHEBI:81915
name: Diphenamid
is_a: CHEBI:51614 ! diarylmethane

[Term]
id: CHEBI:81917
name: fenpropidin
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-fenpropidin. A systemic fungicide, it is used for the control of foliar diseases in cereals and sugar beet." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83293 ! has part (R)-fenpropidin
relationship: BFO:0000051 CHEBI:83294 ! has part (S)-fenpropidin
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:83317 ! has role sterol biosynthesis inhibitor
relationship: RO:0000087 CHEBI:83319 ! has role EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81920
name: flufenacet
def: "An aromatic amide that is acetamide in which the amino hydrogens have been replaced by a propan-2-yl and 4-fluorophenyl groups while the methyl hydrogen is replaced by a [5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38099 ! thiadiazoles
is_a: CHEBI:62733 ! aromatic amide
is_a: CHEBI:83575 ! monofluorobenzenes
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81922
name: flusilazole
def: "An organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by <em>p</em>-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1<em>H</em>-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops." []
is_a: CHEBI:25713 ! organosilicon compound
is_a: CHEBI:83575 ! monofluorobenzenes
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81925
name: fomesafen
def: "An <em>N</em>-sulfonylcarboxamide that is <em>N</em>-(methylsulfonyl)benzamide in which the phenyl ring is substituted by a nitro group at position 2 and a 2-chloro-4-(trifluoromethyl)phenoxy group at position 5. A protoporphyrinogen oxidase inhibitor, it was specially developed for use (generally as the corresponding sodium salt, fomesafen-sodium) for post-emergence control of broad-leaf weeds in soya." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:90852 ! N-sulfonylcarboxamide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:73192 ! has role EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor
relationship: RO:0018034 CHEBI:138163 ! is protonated form of fomesafen(1-)

[Term]
id: CHEBI:81927
name: enilconazole
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-enilconazole. A fungicide used to control a wide range of fungi including <em>Tilletia</em> and <em>Helminthosporium</em> spp. on fruit, vegetables and ornamentals. In veterinary medicine, it is used topically for the treatment of fungal skin infections in cattle, dogs, and horses; it is also used by inhalation for the treatment of aspergillosis in ostriches." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87068 ! imidazole fungicide
is_a: CHEBI:87069 ! imidazole antifungal drug
is_a: CHEBI:87071 ! conazole antifungal drug
relationship: BFO:0000051 CHEBI:83830 ! has part (S)-enilconazole
relationship: BFO:0000051 CHEBI:83831 ! has part (R)-enilconazole
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81934
name: nabam
def: "A dithiocarbamate salt that is the disodium salt of ethylenebis(dithiocarbamic acid). A fungicide, algicide and bactericide used on various crops including on cotton, capsicums, onions and rice crops, it is considered to be a carcinogen, so is not licensed for use within the European Union. Mixing nabam with zinc sulfate affords the fungicide zineb." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:83060 ! dithiocarbamate salt
relationship: BFO:0000051 CHEBI:77308 ! has part ethylenebis(dithiocarbamate)
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81935
name: nitrapyrin
def: "A chloropyridine that is 2-chloropyridine which is substituted by a trichloromethyl group at position 6. It is a nitrification inhibitor that is co-applied with nitrogen fertilizer in agroecosystems." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:148436 ! has role nitrification inhibitor
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical

[Term]
id: CHEBI:81936
name: octhilinone
def: "A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It is no longer approved for use within the European Union." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48902 ! 1,2-thiazoles
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81938
name: captafol
def: "A dicarboximide that captan in which the trichloromethyl group is replaced by a 1,1,2,2-tetrachloroethyl group. A broad-spectrum fungicide used to control diseases in fruit and potatoes, it is no longer approved for use in the European Community." []
is_a: CHEBI:24897 ! isoindoles
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:87198 ! phthalimide fungicide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:81939
name: Pebulate
is_a: CHEBI:32876 ! tertiary amine

[Term]
id: CHEBI:81941
name: prosulfocarb
def: "A monothiocarbamic ester that is carbamothioic <i>S</i>-acid substituted by two propyl groups at the nitrogen atom and a benzyl group at the the sulfur atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:38128 ! monothiocarbamic ester
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81945
name: sulfluramid
def: "A sulfonamide obtained by the formal condensation of perfluorooctane-1-sulfonic acid with  ethylamine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35358 ! sulfonamide
relationship: RO:0000087 CHEBI:22153 ! has role acaricide
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:15862 ! has functional parent ethylamine
relationship: RO:0018038 CHEBI:39421 ! has functional parent perfluorooctane-1-sulfonic acid

[Term]
id: CHEBI:81947
name: terbumeton
def: "A diamino-1,3,5-triazine that is <em>N</em>-<em>tert</em>-butyl-<em>N</em>'-ethyl-1,3,5-triazine-2,4-diamine substituted by a methoxy group at position 6. It is an agrochemical used as a herbicide." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81950
name: Ammonium sulfamate
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:81953
name: chlorimuron
def: "An <em>N</em>-sulfonylurea that is urea in which one of the nitrogens has been substituted by a (2-carboxyphenyl)sulfonyl group, while the other has been substituted by a 4-chloro-6-methoxypyrimidin-2-yl group. An acetolactate synthase inhibitor, it is used (generally as the corresponding ethyl ester) as a herbicide." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38656 ! organochlorine pesticide
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:48471 ! sulfamoylbenzoate
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:22180 ! has role EC 2.2.1.6 (acetolactate synthase) inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide

[Term]
id: CHEBI:81955
name: Cycloate
is_a: CHEBI:17062 ! primary aliphatic amine

[Term]
id: CHEBI:81978
name: Tri-allate
is_a: CHEBI:32876 ! tertiary amine

[Term]
id: CHEBI:81981
name: chlorotoluron
def: "A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a 3-chloro-4-methylphenyl group. A herbicide that is non-toxic to honeybees but moderately toxic to mammals, birds, earthworms and most aquatic organisms." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134043 ! phenylureas
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:81990
name: ethofumesate
def: "A racemate comprising of equimolar amounts of (<i>S</i>)- and (<i>R</i>)-ethofumesate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83769 ! has part (S)-ethofumesate
relationship: BFO:0000051 CHEBI:83770 ! has part (R)-ethofumesate
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82012
name: fluometuron
def: "A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-(trifluoromethyl)phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of broadleaf weeds and annual grasses in cotton." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:157693 ! 3-(3,4-substituted-phenyl)-1,1-dimethylurea
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:26089 ! has role photosystem-II inhibitor
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82017
name: fluroxypyr
def: "An aminopyridine that is pyridin-4-amine substituted by chloro groups at positions 3 and 5, a fluoro group at position 6 and a carboxymethoxy group at position 2." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38207 ! aminopyridine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82019
name: folpet
def: "A member of the class of phthalimides that is phthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethylthio group. An agricultural fungicide, it has been used to control mildew, leaf spot, and other diseases in crops sice the 1950s." []
is_a: CHEBI:33261 ! organosulfur compound
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:87198 ! phthalimide fungicide
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:38817 ! has functional parent phthalimide

[Term]
id: CHEBI:82023
name: iprovalicarb
def: "A diastereoisomeric mixture comprising equimolar amounts of <small>L</small>-(<i>R</i>)- and <small>L</small>-(<i>S</i>)-iprovalicarb. It is a systemic fungicide, specific to oomycetes, used on potatoes and grape vines." []
is_a: CHEBI:60915 ! diastereoisomeric mixture
is_a: CHEBI:87029 ! valinamide fungicide
is_a: CHEBI:87061 ! carbamate fungicide
relationship: BFO:0000051 CHEBI:83590 ! has part L-(R)-iprovalicarb
relationship: BFO:0000051 CHEBI:83591 ! has part L-(S)-iprovalicarb
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:82025
name: napropamide
def: "A racemate composed of equimolar amounts of (<i>S</i>)- and (<i>R</i>)-napropamide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83772 ! has part (R)-napropamide
relationship: BFO:0000051 CHEBI:83773 ! has part (S)-napropamide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82029
name: Oxyfluorfen
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35618 ! aromatic ether
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:73192 ! has role EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor

[Term]
id: CHEBI:82033
name: propamocarb
def: "A carbamate ester that is the propyl ester of 3-(dimethylamino)propylcarbamic acid. It is a systemic fungicide, used (normally as the hydrochloride salt) for the control of soil, root and leaf diseases caused by oomycetes, particularly  <em>Phytophthora </em> and <em>Pythium </em> species." []
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:87061 ! carbamate fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:28831 ! has functional parent propan-1-ol

[Term]
id: CHEBI:82034
name: propaquizafop
def: "A quinoxaline derivative used as systemic herbicide for annual and perennial grasses." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33308 ! carboxylic ester
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:36816 ! oxime O-ether
is_a: CHEBI:38771 ! quinoxaline derivative
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82043
name: tebutam
def: "A monocarboxylic acid amide that is propanamide substituted by a benzyl and an isopropyl group at the nitrogen atom and two methyl groups at position 2. It is an agrochemical used as a herbicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:29347 ! monocarboxylic acid amide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82076
name: anilazine
def: "A member of the class of triazenes that is dichlorotriazene in which the hydrogen is replaced by an <em>o</em>-chloroanilino group. A fungicide formerly used to control leaf spots and downy mildew, it is no longer approved for use within the European Union." []
is_a: CHEBI:38102 ! triazines
is_a: CHEBI:38656 ! organochlorine pesticide
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:82100
name: Isodrin
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:82111
name: Crufomate
is_a: CHEBI:38976 ! alkylbenzene
is_a: CHEBI:60911 ! racemate

[Term]
id: CHEBI:82125
name: Fenchlorphos
is_a: CHEBI:37512 ! organic thiophosphate

[Term]
id: CHEBI:82149
name: TEPP
is_a: CHEBI:62889 ! organic diphosphate

[Term]
id: CHEBI:82163
name: rac-1,2-dichloropropane
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-1,2-dichloropropane. It is used as a fumigant to control nematodes in soil and insects in stored grain." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:142469 ! has part (R)-1,2-dichloropropane
relationship: BFO:0000051 CHEBI:142471 ! has part (S)-1,2-dichloropropane
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:39277 ! has role fumigant insecticide
relationship: RO:0000087 CHEBI:48358 ! has role polar aprotic solvent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:82183
name: Chloramben
is_a: CHEBI:23134 ! chlorobenzoic acid

[Term]
id: CHEBI:82220
name: atraton
def: "A diamino-1,3,5-triazine that is <em>N</em>-ethyl-<em>N</em>'-(propan-2-yl)-1,3,5-triazine-2,4-diamine substituted by a methoxy group at position 6. It is an agrochemical used as a herbicide." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82228
name: secbumeton
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-secbumeton. It is an agrochemical used as a herbicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83787 ! has part (R)-secbumeton
relationship: BFO:0000051 CHEBI:83788 ! has part (S)-secbumeton
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:82244
name: Methazole
is_a: CHEBI:23697 ! dichlorobenzene

[Term]
id: CHEBI:82256
name: ANTU
is_a: CHEBI:25477 ! naphthalenes

[Term]
id: CHEBI:82261
name: Pindone
is_a: CHEBI:140323 ! beta-triketone
is_a: CHEBI:24789 ! indanones

[Term]
id: CHEBI:82270
name: bis(chloromethyl) ether
def: "An ether that is dimethyl ether in which one of the hydrogens attached to each of the methyl group has replaced by a chlorine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:22333 ! has role alkylating agent
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:82271
name: Chloromethyl methyl ether
is_a: CHEBI:25698 ! ether

[Term]
id: CHEBI:82273
name: Benzal chloride
is_a: CHEBI:22712 ! benzenes

[Term]
id: CHEBI:82274
name: (trichloromethyl)benzene
def: "An organochlorine compound that is toluene in which all three hydrogens of the methyl group have been replaced by chlorines. It is used as an intermediate in organic synthesis and dye chemistry." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:134179 ! volatile organic compound
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:82275
name: benzoyl chloride
def: "An acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group. It is an important chemical intermediate for the manufacture of other chemicals, dyes, perfumes, herbicides and pharmaceuticals." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:36687 ! acyl chloride
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0018038 CHEBI:30746 ! has functional parent benzoic acid

[Term]
id: CHEBI:8228
name: pioglitazone
def: "A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:50990 ! thiazolidinediones
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:71554 ! has role PPARgamma agonist
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77194 ! has role EC 2.7.1.33 (pantothenate kinase) inhibitor
relationship: RO:0000087 CHEBI:77307 ! has role cardioprotective agent
relationship: RO:0000087 CHEBI:83157 ! has role EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor

[Term]
id: CHEBI:82280
name: Dimethylcarbamoyl chloride
is_a: CHEBI:37578 ! halide
relationship: RO:0018038 CHEBI:28616 ! has functional parent carbamic acid

[Term]
id: CHEBI:82282
name: tris(2,3-dibromopropyl) phosphate
def: "A trialkyl phosphate that is phosphoric acid in which the three hydroxy groups are substituted by 2,3-dibromopropoxy groups." []
is_a: CHEBI:172368 ! brominated flame retardant
is_a: CHEBI:37562 ! trialkyl phosphate
relationship: RO:0000087 CHEBI:25435 ! has role mutagen
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent

[Term]
id: CHEBI:82285
name: ortho-Aminoazotoluene
is_a: CHEBI:22682 ! azobenzenes

[Term]
id: CHEBI:82288
name: o-anisidine
def: "A substituted aniline that is aniline in which the hydrogen <em>ortho</em> to the amino group has been replaced by a methoxy group. It is used as a chemical intermediate in the synthesis of azo pigments and dyes." []
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50994 ! primary amino compound
relationship: RO:0000087 CHEBI:33893 ! has role reagent
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin

[Term]
id: CHEBI:8229
name: Pioglitazone hydrochloride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent

[Term]
id: CHEBI:82297
name: carbon black
def: "An elemental carbon in the form of virtually pure colloidal particles that are produced by incomplete combustion or thermal decomposition of gaseous or liquid hydrocarbons under controlled conditions. A black, finely divided pellet or powder, its properties of specific surface area, particle size and structure, conductivity and colour can be varied by varying the exact conditions for its production. It is used in tyres, rubber and plastic products, printing inks and coatings." []
is_a: CHEBI:33415 ! elemental carbon

[Term]
id: CHEBI:82304
name: 1-Amino-2,4-dibromoanthraquinone
is_a: CHEBI:22580 ! anthraquinone

[Term]
id: CHEBI:82307
name: para-Cresidine
is_a: CHEBI:51683 ! methoxybenzenes

[Term]
id: CHEBI:82309
name: 2,4-Diaminoanisole
is_a: CHEBI:51683 ! methoxybenzenes

[Term]
id: CHEBI:82315
name: 3,3'-Dichlorobenzidine
is_a: CHEBI:22888 ! biphenyls
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:82318
name: Diglycidyl resorcinol ether
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:82319
name: Dihydrosafrole
is_a: CHEBI:38298 ! benzodioxoles

[Term]
id: CHEBI:82321
name: 3,3'-Dimethoxybenzidine
is_a: CHEBI:22888 ! biphenyls

[Term]
id: CHEBI:82327
name: Ethyl acrylate
is_a: CHEBI:51702 ! enoate ester

[Term]
id: CHEBI:82340
name: 2-Methylaziridine
is_a: CHEBI:22681 ! aziridines

[Term]
id: CHEBI:82342
name: 5-Methylchrysene
is_a: CHEBI:35294 ! carbopolycyclic compound

[Term]
id: CHEBI:82344
name: Methyl isobutyl ketone
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:82351
name: 6-Nitrochrysene
is_a: CHEBI:35294 ! carbopolycyclic compound

[Term]
id: CHEBI:82355
name: 4-Nitropyrene
is_a: CHEBI:59659 ! pyrenes

[Term]
id: CHEBI:82356
name: N-Nitrosodi-n-butylamine
is_a: CHEBI:35800 ! nitroso compound

[Term]
id: CHEBI:82358
name: N-Nitrosodi-n-propylamine
is_a: CHEBI:35800 ! nitroso compound

[Term]
id: CHEBI:82361
name: N-Nitrosomethylvinylamine
is_a: CHEBI:35800 ! nitroso compound

[Term]
id: CHEBI:82367
name: Phenyl glycidyl ether
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:82370
name: 1,3-Propane sultone
is_a: CHEBI:38088 ! sultone

[Term]
id: CHEBI:82372
name: Tetranitromethane
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:82374
name: 4,4'-Thiodianiline
is_a: CHEBI:48975 ! substituted aniline

[Term]
id: CHEBI:82379
name: Allyl chloride
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:82382
name: 1-Amino-2-methylanthraquinone
is_a: CHEBI:22580 ! anthraquinone

[Term]
id: CHEBI:82392
name: Arsenobetaine
is_a: CHEBI:24868 ! organic salt

[Term]
id: CHEBI:82405
name: Benzoyl peroxide
is_a: CHEBI:25702 ! organic peroxide
is_a: CHEBI:36586 ! carbonyl compound
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent

[Term]
id: CHEBI:82409
name: Bis(2-chloro-1-methylethyl)ether
is_a: CHEBI:25698 ! ether

[Term]
id: CHEBI:82411
name: Brilliant Blue
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:82415
name: Chloramine
is_a: CHEBI:37578 ! halide

[Term]
id: CHEBI:82417
name: Chlorodifluoromethane
is_a: CHEBI:134040 ! hydrochlorofluorocarbon

[Term]
id: CHEBI:82436
name: decabromodiphenyl ether
def: "A polybromodiphenyl ether that is diphenyl ether in which all of the hydrogens have been replaced by bromines." []
is_a: CHEBI:134094 ! polybromodiphenyl ether
relationship: RO:0000087 CHEBI:50910 ! has role neurotoxin

[Term]
id: CHEBI:82446
name: trans-1,4-Dichlorobutene
is_a: CHEBI:36683 ! organochlorine compound

[Term]
id: CHEBI:82451
name: 3,3'-Dimethoxybenzidine-4,4'-diisocyanate
is_a: CHEBI:22888 ! biphenyls

[Term]
id: CHEBI:82471
name: Guinea Green B
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:8248
name: pirimicarb
def: "An aminopyrimidine that is <em>N</em>,<em>N</em>,4,5-tetramethylpyrimidin-2-amine substituted by a (dimethylcarbamoyl)oxy group at position 4." []
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38461 ! has role carbamate insecticide
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:38544 ! has functional parent dimethylcarbamic acid

[Term]
id: CHEBI:82482
name: Methyl acrylate
is_a: CHEBI:51702 ! enoate ester

[Term]
id: CHEBI:82492
name: N-Methylolacrylamide
is_a: CHEBI:140325 ! secondary carboxamide

[Term]
id: CHEBI:82496
name: 1,5-Naphthalene diisocyanate
is_a: CHEBI:25477 ! naphthalenes

[Term]
id: CHEBI:82504
name: 4-Nitrobiphenyl
is_a: CHEBI:22888 ! biphenyls

[Term]
id: CHEBI:82534
name: Sudan II
is_a: CHEBI:22682 ! azobenzenes

[Term]
id: CHEBI:82548
name: Vat Yellow 4
is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene

[Term]
id: CHEBI:82550
name: Vinylidene fluoride
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:82632
name: phytochrome chromophore
def: "A chromophore that is a linear tetrapyrrolic prosthetic group covalently attached to a large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far-red light absorbing form." []
is_a: CHEBI:23240 ! chromophore

[Term]
id: CHEBI:82644
name: ractopamine
def: "A diastereoisomeric mixture of approximately equal amounts of all four possible diastereoisomers of 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol. A β-adrenergic agonist, it is used (generally as the hydrochloride salt) as a feed additive for use in pigs and other livestock to promote protein deposition, resulting in leaner meat. The <i>R</i>,<i>R</i> diastereoisomer, butopamine, is responsible for most of the leanness-enhancing effects. While use of ractopamine has been banned in over 120 countries including throughout the EU, in the US it used in an estimated 80% of all beef, pork and turkey production." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:60915 ! diastereoisomeric mixture
relationship: BFO:0000051 CHEBI:82648 ! has part butopamine
relationship: BFO:0000051 CHEBI:82649 ! has part ent-butopamine
relationship: BFO:0000051 CHEBI:82652 ! has part 4-[(1S)-1-hydroxy-2-{[(2R)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl]phenol
relationship: BFO:0000051 CHEBI:82653 ! has part 4-[(1R)-1-hydroxy-2-{[(2S)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl]phenol
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:82655 ! has role animal growth promotant

[Term]
id: CHEBI:82647
name: 4-(1-hydroxy-2-\{[4-(4-hydroxyphenyl)butan-2-yl]amino\}ethyl)phenol
def: "A secondary amino compound that is 4-(2-amino-1-hydroxyethyl)phenol in which one of the hydrogens attached to the nitrogen is replaced by a 4-(<em>p</em>-hydroxyphenyl)butan-2-yl group." []
is_a: CHEBI:22743 ! benzyl alcohols
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:50995 ! secondary amino compound

[Term]
id: CHEBI:82648
name: butopamine
def: "A 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol in which both stereocentres have <i>R</i> configuration. It is the most active of the four diastereoisomers that make up the animal feed additive ractopamine." []
is_a: CHEBI:82647 ! 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol
relationship: RO:0000087 CHEBI:35522 ! has role beta-adrenergic agonist
relationship: RO:0000087 CHEBI:82655 ! has role animal growth promotant
relationship: RO:0018039 CHEBI:82649 ! is enantiomer of ent-butopamine

[Term]
id: CHEBI:82649
name: ent-butopamine
def: "A 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol in which both stereocentres have <i>S</i> configuration." []
is_a: CHEBI:82647 ! 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol
relationship: RO:0018039 CHEBI:82648 ! is enantiomer of butopamine

[Term]
id: CHEBI:82652
name: 4-[(1S)-1-hydroxy-2-\{[(2R)-4-(4-hydroxyphenyl)butan-2-yl]amino\}ethyl]phenol
def: "A 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol in which the carbon bearing the hydroxy group has <i>S</i> configuration while the remaining stereocentre has <i>R</i> configuration." []
is_a: CHEBI:82647 ! 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol
relationship: RO:0018039 CHEBI:82653 ! is enantiomer of 4-[(1R)-1-hydroxy-2-{[(2S)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl]phenol

[Term]
id: CHEBI:82653
name: 4-[(1R)-1-hydroxy-2-\{[(2S)-4-(4-hydroxyphenyl)butan-2-yl]amino\}ethyl]phenol
def: "A 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol in which the carbon bearing the hydroxy group has <i>R</i> configuration while the remaining stereocentre has <i>S</i> configuration." []
is_a: CHEBI:82647 ! 4-(1-hydroxy-2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)phenol
relationship: RO:0018039 CHEBI:82652 ! is enantiomer of 4-[(1S)-1-hydroxy-2-{[(2R)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl]phenol

[Term]
id: CHEBI:82655
name: animal growth promotant
def: "Substances that are administered to farmed animals to improve productivity by promoting weight gain, increasing muscle mass, limiting fat deposition, reducing feed consumption, and reducing waste production." []
is_a: CHEBI:33286 ! agrochemical

[Term]
id: CHEBI:82663
name: elemental iron
def: "An elemental molecular entity in which all of the atoms have atomic number 26." []
is_a: CHEBI:24873 ! iron molecular entity
is_a: CHEBI:33259 ! elemental molecular entity

[Term]
id: CHEBI:82665
name: EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cyclin-dependent kinase (EC 2.7.11.22)." []
is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor

[Term]
id: CHEBI:82680
name: monounsaturated fatty acid anion
def: "Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain." []
is_a: CHEBI:2580 ! unsaturated fatty acid anion
relationship: RO:0018033 CHEBI:25413 ! is deprotonated form of monounsaturated fatty acid

[Term]
id: CHEBI:82711
name: aryl thiol
def: "An aryl thiol is a thiol in which a sulfanyl group, SH, is attached to an aryl group." []
is_a: CHEBI:29256 ! thiol

[Term]
id: CHEBI:82720
name: empagliflozin
def: "A <em>C</em>-glycosyl compound consisting of a β-glucosyl residue having a (4-chloro-3-{4-[(3<i>S</i>)-tetrahydrofuran-3-yloxy]benzyl}phenyl group at the anomeric centre. A sodium-glucose co-transporter 2 inhibitor used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:20857 ! C-glycosyl compound
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:47814 ! tetrahydrofuryl ether
is_a: CHEBI:51614 ! diarylmethane
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:73273 ! has role sodium-glucose transport protein subtype 2 inhibitor
relationship: RO:0000087 CHEBI:76916 ! has role hyperglycemic agent

[Term]
id: CHEBI:8273
name: plumbagin
def: "A  hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:132157 ! hydroxy-1,4-naphthoquinone
is_a: CHEBI:33853 ! phenols
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant

[Term]
id: CHEBI:82744
name: aliphatic aldoxime
def: "Any aldoxime derived from an aliphatic aldehyde." []
is_a: CHEBI:22307 ! aldoxime

[Term]
id: CHEBI:82748
name: cytidine 5'-monophosphate(1-) residue
def: "An organic anionic group that is the conjugate base of CMP residue, obtained by deprotonation of the phosphate OH group; major species at pH 7.3." []
is_a: CHEBI:90675 ! ribonucleotide residue(1-)
relationship: RO:0018033 CHEBI:50308 ! is deprotonated form of cytidine 5'-monophosphate residue
relationship: RO:0018037 CHEBI:60377 ! is substitutent group from cytidine 5'-monophosphate(2-)

[Term]
id: CHEBI:82752
name: eliglustat
def: "A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1<i>R</i>,2<i>R</i>)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease." []
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:46775 ! N-alkylpyrrolidine
is_a: CHEBI:64096 ! benzodioxine
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50382 ! has role EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor
relationship: RO:0018033 CHEBI:83355 ! is deprotonated form of eliglustat(1+)

[Term]
id: CHEBI:82790
name: methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate
def: "An alanine derivative that is methyl alaninate in which one of the hydrogens attached to the nitrogen is substituted by a methoxyacetyl group, while the other is substituted by a 2,6-dimethylphenyl group." []
is_a: CHEBI:22278 ! alanine derivative
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:25698 ! ether
is_a: CHEBI:37622 ! carboxamide
is_a: CHEBI:62733 ! aromatic amide

[Term]
id: CHEBI:82791
name: (S)-metalaxyl
def: "A methyl <em>N</em>-(2,6-dimethylphenyl)-<em>N</em>-(methoxyacetyl)alaninate that is the less active <i>S</i>-enantiomer of metalaxyl." []
is_a: CHEBI:82790 ! methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate
is_a: CHEBI:83943 ! L-alanine derivative
relationship: RO:0018039 CHEBI:60607 ! is enantiomer of metalaxyl-M

[Term]
id: CHEBI:82812
name: diltiazem(1+)
def: "An ammonium ion resulting from the protonation of the nitrogen of the dimethylaminoethyl substituent of diltiazem. The major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35678 ! has role histamine agonist
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0018034 CHEBI:101278 ! is protonated form of diltiazem
relationship: RO:0018039 CHEBI:82816 ! is enantiomer of ent-diltiazem(1+)

[Term]
id: CHEBI:82813
name: ent-diltiazem
def: "A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have <i>R</i> configuration. It is a cGMP-activated K+ channel blocker." []
is_a: CHEBI:82814 ! 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate
relationship: RO:0000087 CHEBI:50509 ! has role potassium channel blocker
relationship: RO:0018033 CHEBI:82816 ! is deprotonated form of ent-diltiazem(1+)
relationship: RO:0018039 CHEBI:101278 ! is enantiomer of diltiazem

[Term]
id: CHEBI:82814
name: 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate
def: "A lactam that is 2,3-dihydro-1,5-benzothiazepin-4(5<em>H</em>)-one in which positions 2 and 3 are substituted by 4-methoxyphenyl and acetoxy, respectively, while the hydrogen attached to the nitrogen is substituted by a 2-(dimethylamino)ethyl group." []
is_a: CHEBI:24995 ! lactam
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:47622 ! acetate ester
is_a: CHEBI:48684 ! benzothiazepine
is_a: CHEBI:50996 ! tertiary amino compound

[Term]
id: CHEBI:82816
name: ent-diltiazem(1+)
def: "An ammonium ion resulting from the protonation of the nitrogen of the dimethylaminoethyl substituent of <em>ent</em>-diltiazem. The major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0000087 CHEBI:50509 ! has role potassium channel blocker
relationship: RO:0018034 CHEBI:82813 ! is protonated form of ent-diltiazem
relationship: RO:0018039 CHEBI:82812 ! is enantiomer of diltiazem(1+)

[Term]
id: CHEBI:82828
name: oleanolate
def: "A monocarboxylic acid anion that is the conjugate base of oleanolic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0018033 CHEBI:37659 ! is deprotonated form of oleanolic acid

[Term]
id: CHEBI:82851
name: phthalimides
def: "A dicarboximide that is phthalimide or derivatives obtained from it by the formal replacement of one or more hydrogens." []
is_a: CHEBI:24897 ! isoindoles
is_a: CHEBI:35356 ! dicarboximide

[Term]
id: CHEBI:82852
name: inosine 5'-phosphate(1-) residue
def: "An organic anionic group obtained by deprotonation of the phosphate function of inosine 5'-phosphate residue; major species at 7.3." []
is_a: CHEBI:64775 ! organic anionic group
relationship: RO:0018033 CHEBI:76778 ! is deprotonated form of IMP residue

[Term]
id: CHEBI:82914
name: p-cresol sulfate
def: "An aryl sulfate that is <em>p</em>-cresol in which the phenolic hydrogen has been replaced by a sulfo group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37919 ! aryl sulfate
relationship: RO:0000087 CHEBI:64584 ! has role uremic toxin
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0000087 CHEBI:82933 ! has role gut flora metabolite
relationship: RO:0018034 CHEBI:133670 ! is protonated form of p-cresol sulfate(1-)
relationship: RO:0018038 CHEBI:17847 ! has functional parent p-cresol

[Term]
id: CHEBI:82933
name: gut flora metabolite
def: "Metabolites produced by the gut microbiota or microorganisms (e.g. bacteria and fungi) that live in the digestive tracts of animals." []
is_a: CHEBI:25212 ! metabolite

[Term]
id: CHEBI:82978
name: paliperidone
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-paliperidone. Paliperidone is the primary active metabolite of the older antipsychotic risperidone and is used for treatment of schizophrenia." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83805 ! has part (S)-paliperidone
relationship: BFO:0000051 CHEBI:83806 ! has part (R)-paliperidone
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0000087 CHEBI:37955 ! has role H1-receptor antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic

[Term]
id: CHEBI:83038
name: Daphnia galeata metabolite
def: "A <em>Daphnia</em> metabolite produced by the species <em>Daphnia galeata</em>." []
is_a: CHEBI:83057 ! Daphnia metabolite

[Term]
id: CHEBI:83039
name: crustacean metabolite
def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." []
is_a: CHEBI:75767 ! animal metabolite

[Term]
id: CHEBI:83056
name: Daphnia magna metabolite
def: "A <em>Daphnia</em> metabolite produced by the species <em>Daphnia magna</em>." []
is_a: CHEBI:83057 ! Daphnia metabolite

[Term]
id: CHEBI:83057
name: Daphnia metabolite
def: "A crustacean metabolite produced by the genus of small planktonic arthropods, <em>Daphnia</em>" []
is_a: CHEBI:83039 ! crustacean metabolite

[Term]
id: CHEBI:83060
name: dithiocarbamate salt
def: "Any salt derived from a member of the class of dithiocarbamic acids by the formal replacement of the hydrogen of the dithiocarboxy group by a metal." []
is_a: CHEBI:24868 ! organic salt
relationship: BFO:0000051 CHEBI:84292 ! has part dithiocarbamate anions

[Term]
id: CHEBI:83061
name: dimethyldithiocarbamic acid
def: "A member of the class of dithiocarbamic acids that is dimethylcarbamic acid in which both of the oxygens are replaced by sulfur." []
is_a: CHEBI:78787 ! dithiocarbamic acids
relationship: RO:0018034 CHEBI:84293 ! is protonated form of dimethyldithiocarbamate

[Term]
id: CHEBI:83072
name: EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
def: "An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1." []
is_a: CHEBI:77102 ! EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor

[Term]
id: CHEBI:83146
name: Daphnia tenebrosa metabolite
def: "A <em>Daphnia</em> metabolite produced by the species <em>Daphnia tenebrosa</em>." []
is_a: CHEBI:83057 ! Daphnia metabolite

[Term]
id: CHEBI:83156
name: EC 6.2.1.* (acid-thiol ligase) inhibitor
def: "An EC 6.2.* (<em>C</em>‒<em>S</em> bond-forming ligase) inhibitor that interferes with the action of an acid-thiol ligase inhibitor (EC 6.2.1.*)." []
is_a: CHEBI:76707 ! EC 6.2.* (C-S bond-forming ligase) inhibitor

[Term]
id: CHEBI:83157
name: EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor
def: "An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of a long-chain-fatty-acid—CoA ligase (EC 6.2.1.3)." []
is_a: CHEBI:83156 ! EC 6.2.1.* (acid-thiol ligase) inhibitor

[Term]
id: CHEBI:83279
name: 3-iodoprop-2-yn-1-yl butylcarbamate
def: "A carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. A fungicide, it is used as a preservative and sapstain control chemical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products." []
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:73474 ! acetylenic compound
is_a: CHEBI:87061 ! carbamate fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:83291
name: 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine
def: "A member of the class of piperidines that is <em>N</em>-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a <em>p</em>-<em>tert</em>-butylphenyl group." []
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:32876 ! tertiary amine

[Term]
id: CHEBI:83293
name: (R)-fenpropidin
def: "A 1-[3-(4-<em>tert</em>-butylphenyl)-2-methylpropyl]piperidine that has <i>R</i> configuration." []
is_a: CHEBI:83291 ! 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine
relationship: RO:0018039 CHEBI:83294 ! is enantiomer of (S)-fenpropidin

[Term]
id: CHEBI:83294
name: (S)-fenpropidin
def: "A 1-[3-(4-<em>tert</em>-butylphenyl)-2-methylpropyl]piperidine that has <i>S</i> configuration." []
is_a: CHEBI:83291 ! 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine
relationship: RO:0018039 CHEBI:83293 ! is enantiomer of (R)-fenpropidin

[Term]
id: CHEBI:83317
name: sterol biosynthesis inhibitor
def: "Any compound that inhibits the biosynthesis of any sterol." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:83319
name: EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor
def: "An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD<small><sup>+</small></sup> or NADP<small><sup>+</small></sup> as acceptor) inhibitor that interferes with the action of Δ<small><sup>14</small></sup>-sterol reductase (EC 1.3.1.70)." []
is_a: CHEBI:76857 ! EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor

[Term]
id: CHEBI:83328
name: pyrazolone
def: "A member of the class of pyrazoles in which one of the carbons of the pyrazole ring is substituted by an oxo group." []
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:36586 ! carbonyl compound

[Term]
id: CHEBI:83347
name: organosulfonic ester
def: "An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid." []
is_a: CHEBI:33424 ! sulfur oxoacid derivative
is_a: CHEBI:35701 ! ester
relationship: RO:0018038 CHEBI:33551 ! has functional parent organosulfonic acid

[Term]
id: CHEBI:83355
name: eliglustat(1+)
def: "An organic cation obtained by protonation of the tertiary amino function of eliglustat." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:82752 ! is protonated form of eliglustat

[Term]
id: CHEBI:83372
name: meptyldinocap
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-meptyldinocap.  A fungicide that is active against powdery mildew mainly on grapes, cucurbits and strawberries. Whilst it is not highly to toxic to birds is is toxic to many aquatic species including fish and algae." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83376 ! has part (R)-meptyldinocap
relationship: BFO:0000051 CHEBI:83378 ! has part (S)-meptyldinocap
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:83375
name: 2,4-dinitro-6-(octan-2-yl)phenyl (E)-but-2-enoate
def: "An enoate ester obtained by formal condensation of the carboxy group of 3-methylacrylic acid with the phenolic hydroxy group of 2,4-dinitro-6-(octan-2-yl)phenol." []
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:51702 ! enoate ester

[Term]
id: CHEBI:83376
name: (R)-meptyldinocap
def: "A 2,4-dinitro-6-(octan-2-yl)phenyl (<i>E</i>)-but-2-enoate that is the (<i>R</i>)-enantiomer of meptyldinocap." []
is_a: CHEBI:83375 ! 2,4-dinitro-6-(octan-2-yl)phenyl (E)-but-2-enoate
relationship: RO:0018039 CHEBI:83378 ! is enantiomer of (S)-meptyldinocap

[Term]
id: CHEBI:83378
name: (S)-meptyldinocap
def: "A 2,4-dinitro-6-(octan-2-yl)phenyl (<i>E</i>)-but-2-enoate that is the (<i>S</i>)-enantiomer of meptyldinocap." []
is_a: CHEBI:83375 ! 2,4-dinitro-6-(octan-2-yl)phenyl (E)-but-2-enoate
relationship: RO:0018039 CHEBI:83376 ! is enantiomer of (R)-meptyldinocap

[Term]
id: CHEBI:83379
name: dinocap
def: "A multi-component mixture comprising 2,6-dinitro-4-octanylphenyl and 2,4-dinitro-6-octanylphenyl esters of (2<i>E</i>)-but-2-enoic acid in which 'octanyl' is a mixture of octan-2-yl, octan-3-yl and octan-4-yl groups. The mixture is used as a protectant fungicide for powdery mildew control. The most active component is 2-(1-methylheptyl)-4,6-dinitrophenyl (2<i>E</i>)-2-butenoate, which has the ISO common name meptyldinocap." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:83380 ! has part dinocap-4
relationship: BFO:0000051 CHEBI:83382 ! has part dinocap-6
relationship: RO:0000087 CHEBI:50905 ! has role teratogenic agent
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:83380
name: dinocap-4
def: "A mixture of 2,6-dinitro-4-octylphenyl crotonates in which 'octyl' is a mixture of 1-methylheptyl, 1-ethylhexyl and 1-propylpentyl groups. A component of dinocap, which is used as a protectant fungicide for powdery mildew control." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:83382
name: dinocap-6
def: "A mixture of 2,4-dinitro-6-octylphenyl crotonates in which 'octyl' is a mixture of 1-methylheptyl, 1-ethylhexyl and 1-propylpentyl groups. A component of dinocap, which is used as a protectant fungicide for powdery mildew control. The most active component is where R = 1-methylheptyl, which has the ISO common name meptyldinocap." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:83372 ! has part meptyldinocap
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:83390
name: pentachlorobenzenes
def: "Any member of the class of chlorobenzenes in which a benzene ring is substituted by five chloro groups." []
is_a: CHEBI:23132 ! chlorobenzenes

[Term]
id: CHEBI:83394
name: 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile
def: "A member of the class of pyrazoles that is 1<em>H</em>-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfinyl, and amino groups, respectively." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:22063 ! sulfoxide
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes

[Term]
id: CHEBI:83395
name: (R)-fipronil
def: "A 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile that has <i>R</i> configuration at the sulfoxide." []
is_a: CHEBI:83394 ! 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile
relationship: RO:0018039 CHEBI:83396 ! is enantiomer of (S)-fipronil

[Term]
id: CHEBI:83396
name: (S)-fipronil
def: "A 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile that has <i>S</i> configuration at the sulfoxide." []
is_a: CHEBI:83394 ! 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile
relationship: RO:0018039 CHEBI:83395 ! is enantiomer of (R)-fipronil

[Term]
id: CHEBI:83399
name: marine xenobiotic metabolite
def: "Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms." []
is_a: CHEBI:76206 ! xenobiotic metabolite
is_a: CHEBI:76507 ! marine metabolite

[Term]
id: CHEBI:83403
name: monochlorobenzenes
def: "Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine." []
is_a: CHEBI:23132 ! chlorobenzenes

[Term]
id: CHEBI:83410
name: alpha-amino acid ester(1+)
def: "A primary ammonium ion obtained by protonation of the amino group of any α-amino acid ester; major species at pH 7.3." []
is_a: CHEBI:65296 ! primary ammonium ion
relationship: RO:0018034 CHEBI:46874 ! is protonated form of alpha-amino acid ester

[Term]
id: CHEBI:83414
name: alkyl sulfate(1-)
def: "An organosulfate oxoanion obtained by deprotonation of the sulfo group of any alkyl sulfate; major species at pH 7.3." []
is_a: CHEBI:58958 ! organosulfate oxoanion
relationship: RO:0018033 CHEBI:29281 ! is deprotonated form of alkyl sulfate

[Term]
id: CHEBI:83426
name: (E)-dimethomorph
def: "An enamide resulting from the formal condensation of (2<i>E</i>)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acrylic acid with the amino group of morpholine. The agricultural fungicide dimethomorph is a mixture of (<i>E</i>)- and (<i>Z</i>)-dimethomorph; only the <i>Z</i> isomer has fungicidal activity." []
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:51751 ! enamide
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:83427
name: (Z)-dimethomorph
def: "An enamide resulting from the formal condensation of (2<i>Z</i>)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acrylic acid with the amino group of morpholine. The agricultural fungicide dimethomorph is a mixture of (<i>E</i>)- and (<i>Z</i>)-dimethomorph; only the <i>Z</i> isomer has fungicidal activity." []
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:51751 ! enamide
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:87134 ! morpholine fungicide

[Term]
id: CHEBI:83445
name: 2-isopropyl-6-methyl-4-pyrimidinone
def: "A  pyrimidone that is pyrimidin-4(1<em>H</em>)-one substituted by a methyl group at position 6 and an isopropyl group at position 2. It is a metabolite of diazinon." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38337 ! pyrimidone
relationship: RO:0000087 CHEBI:83399 ! has role marine xenobiotic metabolite
relationship: RO:0018036 CHEBI:38629 ! is tautomer of 2-isopropyl-6-methylpyrimidin-4-ol

[Term]
id: CHEBI:83453
name: thifensulfuron-methyl
def: "A methyl ester resulting from the formal condensation of the carboxy group of thifensulfuron with methanol. It is used  as a post-emergence herbicide for the control of grass and broad-leaved weeds." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:26588 ! 1,3,5-triazines
is_a: CHEBI:26961 ! thiophenes
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:132053 ! has functional parent thifensulfuron

[Term]
id: CHEBI:83454
name: trinexapac
def: "A monocarboxylic acid that is 3,5-dioxocyclohexanecarboxylic acid substituted by a cyclopropyl(hydroxy)methylidene group at position 4. It is a metabolite of the plant growth regulator trinexapac-ethyl." []
is_a: CHEBI:23482 ! cyclohexanones
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:33823 ! enol
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:55380 ! beta-hydroxy ketone
relationship: RO:0000087 CHEBI:26155 ! has role plant growth regulator
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:73193 ! has role gibberellin biosynthesis inhibitor
relationship: RO:0000087 CHEBI:83399 ! has role marine xenobiotic metabolite

[Term]
id: CHEBI:83455
name: 5-methyl-1H-benzotriazole
def: "A member of the class of  benzotriazoles that is 1<em>H</em>-benzotriazole substituted by a methyl group at position 5." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48912 ! benzotriazoles
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83465
name: sulcotrione
def: "An  aromatic ketone that is cyclohexane-1,3-dione substituted by a 2-chloro-4-(methylsulfonyl)benzoyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140323 ! beta-triketone
is_a: CHEBI:23482 ! cyclohexanones
is_a: CHEBI:35850 ! sulfone
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:138208 ! has role carotenoid biosynthesis inhibitor
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83490
name: 3,5,6-trichloropyridine-2-one
def: "A pyridone that is pyridin-2(1<em>H</em>)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38183 ! pyridone
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:83399 ! has role marine xenobiotic metabolite
relationship: RO:0018036 CHEBI:143794 ! is tautomer of 3,5,6-trichloro-2-pyridinol

[Term]
id: CHEBI:83491
name: perfluoropentanoic acid
def: "A monocarboxylic acid that is perfluorinated pentanoic acid." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:17418 ! has functional parent valeric acid

[Term]
id: CHEBI:83492
name: perfluorohexanoic acid
def: "A monocarboxylic acid that is perfluorinated hexanoic acid." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:30776 ! has functional parent hexanoic acid

[Term]
id: CHEBI:83493
name: perfluoroundecanoic acid
def: "A fluoroalkanoic acid that is perfluorinated undecanoic acid." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:32368 ! has functional parent undecanoic acid

[Term]
id: CHEBI:83494
name: 6:2 fluorotelomer unsaturated carboxylic acid
def: "A fluorotelomer that is oct-2-enoic acid substituted by fluoro groups at positions 3, 4, 4, 5, 5,6, 6, 7, 7, 8, 8 and 8 respectively." []
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
is_a: CHEBI:83814 ! fluorotelomer
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:83495
name: 8:2 fluorotelomer unsaturated carboxylic acid
def: "A fluorotelomer that is dec-2-enoic acid substituted by fluoro groups at positions 3, 4, 4, 5, 5, 6, 6, 7, 7, 8, 8, 9, 9, 10, 10 and 10 respectively." []
is_a: CHEBI:79020 ! alpha,beta-unsaturated monocarboxylic acid
is_a: CHEBI:83814 ! fluorotelomer
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77853 ! has role persistent organic pollutant

[Term]
id: CHEBI:83499
name: climbazole
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-climbazole. It is a topically applied antifungal agent used to treat human fungal skin infections." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87069 ! imidazole antifungal drug
is_a: CHEBI:87071 ! conazole antifungal drug
relationship: BFO:0000051 CHEBI:83720 ! has part (R)-climbazole
relationship: BFO:0000051 CHEBI:83722 ! has part (S)-climbazole
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83500
name: tritosulfuron
def: "A sulfonamide  that is benzenesulfonamide substituted by a trifluoromethyl group at position 2 and a [4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-yl]carbamoyl group at the nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
is_a: CHEBI:76983 ! N-sulfonylurea
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83501
name: acesulfame
def: "A sulfamate ester that is 1,2,3-oxathiazin-4(3<em>H</em>)-one 2,2-dioxide substituted by a methyl group at position 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25693 ! organic heteromonocyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound
is_a: CHEBI:38104 ! oxacycle
is_a: CHEBI:48199 ! sulfamate ester
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83502
name: foramsulfuron
def: "A member of the class of  benzamides that is <em>N</em>,<em>N</em>-dimethylbenzamide substituted by a formylamino group at position 4 and a [(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:47857 ! ureas
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83503
name: neotame
def: "A dipeptide composed of <em>N</em>-(3,3-dimethylbutyl)-<small>L</small>-aspartic acid and methyl <small>L</small>-phenylalanate units joined by a peptide linkage." []
is_a: CHEBI:46761 ! dipeptide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83505
name: perfluorooctane sulfonamidoacetic acid
def: "A monocarboxylic acid that is (sulfoamino)acetic acid substituted by a heptadecafluorooctyl group at the sulfur atom." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:138089 ! has functional parent perfluorooctanesulfonamide
relationship: RO:0018038 CHEBI:39421 ! has functional parent perfluorooctane-1-sulfonic acid

[Term]
id: CHEBI:83506
name: N-methylperfluorooctane sulfonamidoacetic acid
def: "A sulfonamide that is the <em>N</em>-methyl derivative of perfluorooctane sulfonamidoacetic acid." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83507
name: N-ethylperfluorooctane sulfonamidoacetic acid
def: "A sulfonamide that is the <em>N</em>-ethyl derivative of perfluorooctane sulfonamidoacetic acid." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83508
name: perfluorooctyl phosphate
def: "A monoalkyl phosphate that is 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol in which the hydroxyl hydrogen is substituted by a phosphate group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25381 ! monoalkyl phosphate
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83517
name: iooxitalamic acid
def: "An  organoiodine compound that is 2,4,6-triiodobenzoic acid substituted by an acetylamino group at position 3 and a (2-hydroxyethyl)carbamoyl group at position 5. It is used as a contrast medium." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:35735 ! dicarboxylic acid monoamide
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:48470 ! amidobenzoic acid
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37338 ! has role radioopaque medium
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83518
name: 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone
def: "A 1,2-thiazole that is 1,2-thiazol-3(2<em>H</em>)-one substituted by chloro groups at positions 4 and 5 and an octyl group at position 2. It is used as a fungicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:48902 ! 1,2-thiazoles
relationship: RO:0000087 CHEBI:24127 ! has role fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83521
name: sebuthylazine
def: "A racemate composed of equimolar amounts of (<i>R</i>)- and (<i>S</i>)-sebuthylazine. It is an agrochemical used as a herbicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83790 ! has part (R)-sebuthylazine
relationship: BFO:0000051 CHEBI:83791 ! has part (S)-sebuthylazine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83523
name: pethoxamide
def: "A monocarboxylic acid amide that is acetamide substituted by a chloro group at position 2 and a  2-ethoxyethyl and a 2-methyl-1-phenylprop-1-en-1-yl at the nitrogen atom. It is an agrochemical used as a herbicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83524
name: pinoxaden
def: "A pyrazolooxadiazepine that is 7-oxo-1,2,4,5-tetrahydro-7<em>H</em>-pyrazolo[1,2-<em>d</em>][1,4,5]oxadiazepin which is substituted at positions 8 and 9 by 2,6-diethyl-4-methylphenyl and pivaloyloxy groups, respectively. A pro-herbicide (by hydrolysis of the pivalate ester to give the corresponding enol), it is used for control of grass weeds in cereal crops." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:136684 ! pyrazolooxadiazepine
is_a: CHEBI:50784 ! pivalate ester
relationship: RO:0000087 CHEBI:136646 ! has role proherbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:141347 ! has functional parent pinoxaden acid

[Term]
id: CHEBI:83531
name: moclobemide
def: "A member of the class of  benzamides that is benzamide substituted by a chloro group at position 4 and a 2-(morpholin-4-yl)ethyl group at the nitrogen atom. It acts as a reversible monoamine oxidase inhibitor and is used in the treatment of depression." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83535
name: neohesperidin dihydrochalcone
def: "A member of the  dihydrochalcones that is 3,2',4',6'-tetrahydroxy-4-methoxydihydrochalcone attached to a neohesperidosyl residue at position 4' via glycosidic linkage. It is found in sweet orange." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25495 ! neohesperidoside
is_a: CHEBI:71230 ! dihydrochalcones
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50505 ! has role sweetening agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83536
name: 1-(3-(trifluoromethyl)phenyl)piperazine
def: "A <em>N</em>-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug." []
is_a: CHEBI:46848 ! N-arylpiperazine
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes
relationship: RO:0000087 CHEBI:35471 ! has role psychotropic drug
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35941 ! has role serotonergic agonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83537
name: 1-benzylpiperazine
def: "A tertiary amino compound that is piperazine substituted by a benzyl group at position 1. It is a  serotonergic agonist used as a recreational drug." []
is_a: CHEBI:46845 ! N-alkylpiperazine
relationship: RO:0000087 CHEBI:35471 ! has role psychotropic drug
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35941 ! has role serotonergic agonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83539
name: bisperfluorooctyl phosphate
def: "A dialkyl phosphate in which the alkyl group specified is perfluorooctyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83540
name: bisperfluorodecyl phosphate
def: "A dialkyl phosphate in which the alkyl group specified is perfluorodecyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:16648 ! dialkyl phosphate
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83541
name: perfluorodecyl phosphate
def: "A monoalkyl phosphate in which the alkyl group specified is perfluorodecyl." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25381 ! monoalkyl phosphate
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83563
name: long-chain alkane
def: "Any alkane having a chain length of at least 13 carbon atoms." []
is_a: CHEBI:18310 ! alkane

[Term]
id: CHEBI:83565
name: (trifluoromethyl)benzenes
def: "An organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:37143 ! organofluorine compound
relationship: BFO:0000051 CHEBI:50127 ! has part trifluoromethyl group

[Term]
id: CHEBI:83569
name: pendimethalin
def: "A member of the class of substituted anilines that is <em>N</em>-(pentan-3-yl)aniline bearing two additional nitro substituents at positions 2 and 6 as well as two methyl substituents at positions 3 and 4. A herbicide used to control most annual grasses and many annual broad-leaved weeds." []
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:83571
name: tribenuron
def: "An <em>N</em>-sulfonylurea that is <em>N</em>-(2-carboxybenzenesulfonyl)urea bearing additional methyl and 4-methoxy-6-methyl-1,3,5-triazin-2-yl substituents at position N3. A foliar acting, post-emergence herbicide used to control broad-leaved weeds in cereals, normally used as the methyl variant." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide

[Term]
id: CHEBI:83575
name: monofluorobenzenes
def: "Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent." []
is_a: CHEBI:35496 ! fluorobenzenes

[Term]
id: CHEBI:83576
name: trifluorobenzene
def: "Any member of the class of fluorobenzenes carrying three fluorine substituents at unspecified positions." []
is_a: CHEBI:35496 ! fluorobenzenes

[Term]
id: CHEBI:83590
name: L-(R)-iprovalicarb
def: "The stereoisomer of isopropyl (3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl)carbamate resulting from the formal condensation of <small>L</small>-valine <em>N</em><small><sup>α</small></sup>-isopropyl carbamate with (1<i>R</i>)-1-(<em>p</em>-tolyl)ethylamine." []
is_a: CHEBI:83593 ! isopropyl (3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl)carbamate

[Term]
id: CHEBI:83591
name: L-(S)-iprovalicarb
def: "The stereoisomer of isopropyl (3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl)carbamate resulting from the formal condensation of <small>L</small>-valine <em>N</em><small><sup>α</small></sup>-isopropyl carbamate with (1<i>S</i>)-1-(<em>p</em>-tolyl)ethylamine." []
is_a: CHEBI:83593 ! isopropyl (3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl)carbamate

[Term]
id: CHEBI:83593
name: isopropyl (3-methyl-1-\{[1-(4-methylphenyl)ethyl]amino\}-1-oxobutan-2-yl)carbamate
def: "A carbamate ester that is valinamide in which one of the hydrogens attached to the amide nitrogen is replaced by a 1-(<em>p</em>-tolyl)ethyl group and the α-amino group has been converted to the corresponding isopropyl carbamate." []
is_a: CHEBI:22475 ! amino acid amide
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:27267 ! valine derivative

[Term]
id: CHEBI:83598
name: 2-(4-\{[5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoic acid
def: "A monocarboxylic acid that is propanoic acid substituted by a 4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy group at position 2." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:83599
name: fluazifop-P
def: "A 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid that has <i>R</i> configuration. It is the active enantiomer of the herbicide fluazifop and is the major metabolite of fluazifop-P-butyl." []
is_a: CHEBI:83598 ! 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:60575 ! has role phenoxy herbicide
relationship: RO:0000087 CHEBI:70722 ! has role EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor
relationship: RO:0018039 CHEBI:83600 ! is enantiomer of (S)-fluazifop

[Term]
id: CHEBI:83600
name: (S)-fluazifop
def: "The (<i>S</i>)-enantiomer of 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid. It is the inactive enantiomer of the racemic herbicide fluazifop." []
is_a: CHEBI:83598 ! 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid
relationship: RO:0018039 CHEBI:83599 ! is enantiomer of fluazifop-P

[Term]
id: CHEBI:83628
name: N-acylammonia
def: "A carboxamide obtained by the formal condensation of the carboxy group of any carboxylic acid with ammonia." []
is_a: CHEBI:37622 ! carboxamide

[Term]
id: CHEBI:83630
name: essential oil
def: "A mixture that is a concentrated hydrophobic liquid containing volatile aroma compounds obtained from plants, commonly by distillation (particularly steam distillation), but also by solvent extraction, or by crushing of seeds or fruits in a press." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:60004 ! mixture
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:83632
name: 2-(butan-2-yl)-4,6-dinitrophenol
def: "A dinitrophenol that is 2,4-dinitrophenol substituted by a butan-2-yl group at position 2." []
is_a: CHEBI:39352 ! dinitrophenol

[Term]
id: CHEBI:83633
name: (R)-dinoseb
def: "The (<i>R</i>)-enantiomer of 2-(butan-2-yl)-4,6-dinitrophenol." []
is_a: CHEBI:83632 ! 2-(butan-2-yl)-4,6-dinitrophenol
relationship: RO:0018039 CHEBI:83636 ! is enantiomer of (S)-dinoseb

[Term]
id: CHEBI:83636
name: (S)-dinoseb
def: "The (<i>S</i>)-enantiomer of 2-(butan-2-yl)-4,6-dinitrophenol." []
is_a: CHEBI:83632 ! 2-(butan-2-yl)-4,6-dinitrophenol
relationship: RO:0018039 CHEBI:83633 ! is enantiomer of (R)-dinoseb

[Term]
id: CHEBI:83638
name: 2-chloro-N-(2,4-dimethylthiophen-3-yl)-N-(1-methoxypropan-2-yl)acetamide
def: "An  organochlorine compound that is 2-chloroacetamide substituted by a 2,4-dimethylthiophen-3-yl and a 1-methoxypropan-2-yl group at the nitrogen atom." []
is_a: CHEBI:25698 ! ether
is_a: CHEBI:26961 ! thiophenes
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:62733 ! aromatic amide

[Term]
id: CHEBI:83639
name: (R)-dimethenamid
def: "A 2-chloro-<em>N</em>-(2,4-dimethylthiophen-3-yl)-<em>N</em>-[(2<i>R</i>)-1-methoxypropan-2-yl]acetamide that has <i>R</i> configuration. It is the inactive enantiomer; its (active) enantiomer is the herbicide known as dimethenamid-P; the racemate is the herbicide dimethenamid." []
is_a: CHEBI:83638 ! 2-chloro-N-(2,4-dimethylthiophen-3-yl)-N-(1-methoxypropan-2-yl)acetamide
relationship: RO:0018039 CHEBI:83640 ! is enantiomer of dimethenamid-P

[Term]
id: CHEBI:83640
name: dimethenamid-P
def: "The (<i>S</i>)-enantiomer of 2-chloro-<em>N</em>-(2,4-dimethylthiophen-3-yl)-<em>N</em>-[(2<i>S</i>)-1-methoxypropan-2-yl]acetamide. It is the active enantiomer of dimethenamid, a herbicide applied to the soil to control various broad-leaved weeds and grasses." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:83638 ! 2-chloro-N-(2,4-dimethylthiophen-3-yl)-N-(1-methoxypropan-2-yl)acetamide
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:64911 ! has role antimitotic
relationship: RO:0018039 CHEBI:83639 ! is enantiomer of (R)-dimethenamid

[Term]
id: CHEBI:83645
name: 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide
def: "An  organochlorine compound that is 2-chloroacetamide substituted by a (2-ethyl-6-methylphenyl)-<em>N</em>-(1-methoxypropan-2-yl) group at the nitrogen atom." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:25698 ! ether
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:62733 ! aromatic amide

[Term]
id: CHEBI:83646
name: (R)-metolachlor
def: "The (<i>R</i>)-enantiomer of 2-chloro-<em>N</em>-(2-ethyl-6-methylphenyl)-<em>N</em>-(1-methoxypropan-2-yl)acetamide." []
is_a: CHEBI:83645 ! 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide
relationship: RO:0018039 CHEBI:83647 ! is enantiomer of (S)-metolachlor

[Term]
id: CHEBI:83647
name: (S)-metolachlor
def: "The (<i>S</i>)-enantiomer of 2-chloro-<em>N</em>-(2-ethyl-6-methylphenyl)-<em>N</em>-(1-methoxypropan-2-yl)acetamide." []
is_a: CHEBI:83645 ! 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide
relationship: RO:0018039 CHEBI:83646 ! is enantiomer of (R)-metolachlor

[Term]
id: CHEBI:83658
name: 5-bromo-3-(butan-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione
def: "A pyrimidone that is pyrimidine-2,4(1<em>H</em>,3<em>H</em>)-dione substituted by a bromo group at position 5, a butan-2-yl group at position 3 and a methyl group at position 6." []
is_a: CHEBI:37141 ! organobromine compound
is_a: CHEBI:38337 ! pyrimidone

[Term]
id: CHEBI:83659
name: (R)-bromacil
def: "The (<i>R</i>)-enantiomer of 5-bromo-3-(butan-2-yl)-6-methylpyrimidine-2,4(1<em>H</em>,3<em>H</em>)-dione." []
is_a: CHEBI:83658 ! 5-bromo-3-(butan-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione
relationship: RO:0018039 CHEBI:83660 ! is enantiomer of (S)-bromacil

[Term]
id: CHEBI:83660
name: (S)-bromacil
def: "The (<i>S</i>)-enantiomer of 5-bromo-3-(butan-2-yl)-6-methylpyrimidine-2,4(1<em>H</em>,3<em>H</em>)-dione." []
is_a: CHEBI:83658 ! 5-bromo-3-(butan-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione
relationship: RO:0018039 CHEBI:83659 ! is enantiomer of (R)-bromacil

[Term]
id: CHEBI:83686
name: (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol
def: "A member of the class of pyrimidines that is pyrimidin-5-ylmethanol in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 2-chlorophenyl group while the other is replaced by a 4-chlorophenyl group." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:83688
name: (R)-fenarimol
def: "A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has <i>R</i> configuration." []
is_a: CHEBI:83686 ! (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol
relationship: RO:0018039 CHEBI:83689 ! is enantiomer of (S)-fenarimol

[Term]
id: CHEBI:83689
name: (S)-fenarimol
def: "A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has <i>S</i> configuration." []
is_a: CHEBI:83686 ! (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol
relationship: RO:0018039 CHEBI:83688 ! is enantiomer of (R)-fenarimol

[Term]
id: CHEBI:83719
name: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
def: "A ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1<em>H</em>-imidazol-1-yl group at position 1 and 2 methyl groups at position 3." []
is_a: CHEBI:141498 ! hemiaminal ether
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:83720
name: (R)-climbazole
def: "The (<i>R</i>)-enantiomer of 1-(4-chlorophenoxy)-1-(1<em>H</em>-imidazol-1-yl)-3,3-dimethylbutan-2-one." []
is_a: CHEBI:83719 ! 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
relationship: RO:0018039 CHEBI:83722 ! is enantiomer of (S)-climbazole

[Term]
id: CHEBI:83722
name: (S)-climbazole
def: "The (<i>S</i>)-enantiomer of 1-(4-chlorophenoxy)-1-(1<em>H</em>-imidazol-1-yl)-3,3-dimethylbutan-2-one." []
is_a: CHEBI:83719 ! 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
relationship: RO:0018039 CHEBI:83720 ! is enantiomer of (R)-climbazole

[Term]
id: CHEBI:83729
name: 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile
def: "A nitrile that is hexanenitrile substituted at the 2-position by <em>p</em>-chlorophenyl and (1,2,4-triazol-1-yl)methyl groups." []
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:83730
name: (R)-myclobutanil
def: "A 2-(4-chlorophenyl)-2-(1<em>H</em>-1,2,4-triazol-1-ylmethyl)hexanenitrile that has <i>R</i> configuration." []
is_a: CHEBI:83729 ! 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile
relationship: RO:0018039 CHEBI:83731 ! is enantiomer of (S)-myclobutanil

[Term]
id: CHEBI:83731
name: (S)-myclobutanil
def: "A 2-(4-chlorophenyl)-2-(1<em>H</em>-1,2,4-triazol-1-ylmethyl)hexanenitrile that has <i>S</i> configuration." []
is_a: CHEBI:83729 ! 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile
relationship: RO:0018039 CHEBI:83730 ! is enantiomer of (R)-myclobutanil

[Term]
id: CHEBI:83732
name: 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione
def: "A member of the class of oxazolidinones that is 5-ethenyl-5-methyl-2,4-oxazolidinedione in which the imide hydrogen is replaced by a 3,5-dichlorophenyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:35356 ! dicarboximide
is_a: CHEBI:55374 ! oxazolidinone
is_a: CHEBI:78840 ! olefinic compound

[Term]
id: CHEBI:83733
name: (R)-vinclozolin
def: "A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (<i>R</i>)-enantiomer of vinclozolin." []
is_a: CHEBI:83732 ! 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione
relationship: RO:0018039 CHEBI:83735 ! is enantiomer of (S)-vinclozolin

[Term]
id: CHEBI:83734
name: sterol demethylation inhibitor
def: "A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis." []
is_a: CHEBI:35718 ! antifungal agent
is_a: CHEBI:83317 ! sterol biosynthesis inhibitor

[Term]
id: CHEBI:83735
name: (S)-vinclozolin
def: "A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (<i>S</i>)-enantiomer of vinclozolin." []
is_a: CHEBI:83732 ! 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione
relationship: RO:0018039 CHEBI:83733 ! is enantiomer of (R)-vinclozolin

[Term]
id: CHEBI:83741
name: phospholipid biosynthesis inhibitor
def: "Any compound that inhibits the biosynthesis of any phospholipid." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:83742
name: 2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)-5-(methoxymethyl)nicotinic acid
def: "A pyridinemonocarboxylic acid that is nicotinic acid which is substituted substituted at position 5 by a methoxymethyl group and at position 2 by a 4,5-dihydro-1<em>H</em>-imidazol-2-yl group, that in turn is substituted by isopropyl, methyl, and oxo groups at positions 4, 4, and 5, respectively." []
is_a: CHEBI:20432 ! imidazolone
is_a: CHEBI:25698 ! ether
is_a: CHEBI:26420 ! pyridinemonocarboxylic acid
is_a: CHEBI:53095 ! imidazolines

[Term]
id: CHEBI:83743
name: (S)-imazamox
def: "The (<i>S</i>)-enantiomer of 2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1<em>H</em>-imidazol-2-yl)-5-(methoxymethyl)nicotinic acid." []
is_a: CHEBI:83742 ! 2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)-5-(methoxymethyl)nicotinic acid
relationship: RO:0018034 CHEBI:133193 ! is protonated form of (S)-imazamox(1-)
relationship: RO:0018039 CHEBI:83744 ! is enantiomer of (R)-imazamox

[Term]
id: CHEBI:83744
name: (R)-imazamox
def: "The (<i>R</i>)-enantiomer of 5-(methoxymethyl)-2-[4-methyl-5-oxo-4-(propan-2-yl)-4,5-dihydro-1<em>H</em>-imidazol-2-yl]pyridine-3-carboxylic acid." []
is_a: CHEBI:83742 ! 2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)-5-(methoxymethyl)nicotinic acid
relationship: RO:0018034 CHEBI:131899 ! is protonated form of (R)-imazamox(1-)
relationship: RO:0018039 CHEBI:83743 ! is enantiomer of (S)-imazamox

[Term]
id: CHEBI:83748
name: 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
def: "A tertiary alcohol that is butan-2-ol substituted by a 4-chlorophenyl group at position 2, a cyclopropyl group at position 3 and a 1<em>H</em>-1,2,4-triazol-1-yl group at position 1." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:83749
name: (2R,3S)-cyproconazole
def: "The (2<i>R</i>,3<i>S</i>)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1<em>H</em>-1,2,4-triazol-1-yl)butan-2-ol." []
is_a: CHEBI:83748 ! 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
relationship: RO:0018039 CHEBI:83752 ! is enantiomer of (2S,3R)-cyproconazole

[Term]
id: CHEBI:83750
name: (2S,3S)-cyproconazole
def: "The (2<i>S</i>,3<i>S</i>)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1<em>H</em>-1,2,4-triazol-1-yl)butan-2-ol." []
is_a: CHEBI:83748 ! 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
relationship: RO:0018039 CHEBI:83753 ! is enantiomer of (2R,3R)-cyproconazole

[Term]
id: CHEBI:83752
name: (2S,3R)-cyproconazole
def: "The (2<i>S</i>,3<i>R</i>)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1<em>H</em>-1,2,4-triazol-1-yl)butan-2-ol." []
is_a: CHEBI:83748 ! 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
relationship: RO:0018039 CHEBI:83749 ! is enantiomer of (2R,3S)-cyproconazole

[Term]
id: CHEBI:83753
name: (2R,3R)-cyproconazole
def: "The (2<i>R</i>,3<i>R</i>)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1<em>H</em>-1,2,4-triazol-1-yl)butan-2-ol." []
is_a: CHEBI:83748 ! 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
relationship: RO:0018039 CHEBI:83750 ! is enantiomer of (2S,3S)-cyproconazole

[Term]
id: CHEBI:83758
name: 1-\{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl\}-1H-1,2,4-triazole
def: "An  epoxide that is oxirane substituted by a 2-chlorophenyl, 4-fluorophenyl and a 1<em>H</em>-1,2,4-triazol-1-ylmethyl groups." []
is_a: CHEBI:32955 ! epoxide
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:83403 ! monochlorobenzenes
is_a: CHEBI:83575 ! monofluorobenzenes

[Term]
id: CHEBI:83759
name: (2S,3R)-epoxiconazole
def: "The (2<i>S</i>,3<i>R</i>)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1<em>H</em>-1,2,4-triazole." []
is_a: CHEBI:83758 ! 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole
relationship: RO:0018039 CHEBI:83761 ! is enantiomer of (2R,3S)-epoxiconazole

[Term]
id: CHEBI:83761
name: (2R,3S)-epoxiconazole
def: "The (2<i>R</i>,3<i>S</i>)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1<em>H</em>-1,2,4-triazole." []
is_a: CHEBI:83758 ! 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole
relationship: RO:0018039 CHEBI:83759 ! is enantiomer of (2S,3R)-epoxiconazole

[Term]
id: CHEBI:83766
name: olaparib
def: "A member of the class of <em>N</em>-acylpiperazines obtained by formal condensation of the carboxy group of 2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoic acid with the free amino group of <em>N</em>-(cyclpropylcarbonyl)piperazine; used to treat advanced ovarian cancer." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38768 ! phthalazines
is_a: CHEBI:46844 ! N-acylpiperazine
is_a: CHEBI:51454 ! cyclopropanes
is_a: CHEBI:83575 ! monofluorobenzenes
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:62913 ! has role EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:83768
name: 2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl methanesulfonate
def: "A methanesulfonate ester that is methanesulfonic acid in which the hydrogen of the hydroxy group has been replaced by a 2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl group." []
is_a: CHEBI:25223 ! methanesulfonate ester
is_a: CHEBI:25698 ! ether
is_a: CHEBI:38830 ! 1-benzofurans

[Term]
id: CHEBI:83769
name: (S)-ethofumesate
def: "The (<i>S</i>)-enantiomer of  2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl methanesulfonate." []
is_a: CHEBI:83768 ! 2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl methanesulfonate
relationship: RO:0018039 CHEBI:83770 ! is enantiomer of (R)-ethofumesate

[Term]
id: CHEBI:83770
name: (R)-ethofumesate
def: "The (<i>R</i>)-enantiomer of  2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl methanesulfonate." []
is_a: CHEBI:83768 ! 2-ethoxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl methanesulfonate
relationship: RO:0018039 CHEBI:83769 ! is enantiomer of (S)-ethofumesate

[Term]
id: CHEBI:83771
name: N,N-diethyl-2-(naphthalen-1-yloxy)propanamide
def: "A monocarboxylic acid amide that is propanamide substituted by two ethyl groups at the nitrogen atom and a naphthalen-1-yloxy group at position 2." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:35618 ! aromatic ether

[Term]
id: CHEBI:83772
name: (R)-napropamide
def: "The (<i>R</i>)-enantiomer of <em>N</em>,<em>N</em>-diethyl-2-(naphthalen-1-yloxy)propanamide." []
is_a: CHEBI:83771 ! N,N-diethyl-2-(naphthalen-1-yloxy)propanamide
relationship: RO:0018039 CHEBI:83773 ! is enantiomer of (S)-napropamide

[Term]
id: CHEBI:83773
name: (S)-napropamide
def: "The (<i>S</i>)-enantiomer of <em>N</em>,<em>N</em>-diethyl-2-(naphthalen-1-yloxy)propanamide." []
is_a: CHEBI:83771 ! N,N-diethyl-2-(naphthalen-1-yloxy)propanamide
relationship: RO:0018039 CHEBI:83772 ! is enantiomer of (R)-napropamide

[Term]
id: CHEBI:83779
name: 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol
def: "A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1<em>H</em>-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively." []
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:8378
name: prednisolone
def: "A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding β-hydroxy group. It is a drug metabolite of prednisone." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:61313 ! C21-steroid
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35816 ! has role leprostatic drug
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:37962 ! has role adrenergic agent
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50671 ! has role antithyroid drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:34073 ! has functional parent Delta(1)-progesterone

[Term]
id: CHEBI:83780
name: (S)-tebuconazole
def: "The (<i>S</i>)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1<em>H</em>-1,2,4-triazol-1-ylmethyl)pentan-3-ol." []
is_a: CHEBI:83779 ! 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol
relationship: RO:0018039 CHEBI:83781 ! is enantiomer of (R)-tebuconazole

[Term]
id: CHEBI:83781
name: (R)-tebuconazole
def: "The (<i>R</i>)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1<em>H</em>-1,2,4-triazol-1-ylmethyl)pentan-3-ol." []
is_a: CHEBI:83779 ! 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol
relationship: RO:0018039 CHEBI:83780 ! is enantiomer of (S)-tebuconazole

[Term]
id: CHEBI:83786
name: N-(butan-2-yl)-N'-ethyl-6-methoxy-1,3,5-triazine-2,4-diamine
def: "A diamino-1,3,5-triazine that is <em>N</em>-(butan-2-yl)-<em>N</em>'-ethyl-1,3,5-triazine-2,4-diamine substituted by a methoxy group at position 6." []
is_a: CHEBI:38170 ! diamino-1,3,5-triazine
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine

[Term]
id: CHEBI:83787
name: (R)-secbumeton
def: "The (<i>R</i>)-enantiomer of <em>N</em>-(butan-2-yl)-<em>N</em>'-ethyl-6-methoxy-1,3,5-triazine-2,4-diamine." []
is_a: CHEBI:83786 ! N-(butan-2-yl)-N'-ethyl-6-methoxy-1,3,5-triazine-2,4-diamine
relationship: RO:0018039 CHEBI:83788 ! is enantiomer of (S)-secbumeton

[Term]
id: CHEBI:83788
name: (S)-secbumeton
def: "The (<i>S</i>)-enantiomer of <em>N</em>-(butan-2-yl)-<em>N</em>'-ethyl-6-methoxy-1,3,5-triazine-2,4-diamine." []
is_a: CHEBI:83786 ! N-(butan-2-yl)-N'-ethyl-6-methoxy-1,3,5-triazine-2,4-diamine
relationship: RO:0018039 CHEBI:83787 ! is enantiomer of (R)-secbumeton

[Term]
id: CHEBI:83789
name: N-(butan-2-yl)-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine
def: "A diamino-1,3,5-triazine that is <em>N</em>-(butan-2-yl)-<em>N</em>'-ethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6." []
is_a: CHEBI:38168 ! chloro-1,3,5-triazine
is_a: CHEBI:38170 ! diamino-1,3,5-triazine

[Term]
id: CHEBI:83790
name: (R)-sebuthylazine
def: "The (<i>R</i>)-enantiomer of <em>N</em>-(butan-2-yl)-6-chloro-<em>N</em>'-ethyl-1,3,5-triazine-2,4-diamine." []
is_a: CHEBI:83789 ! N-(butan-2-yl)-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine

[Term]
id: CHEBI:83791
name: (S)-sebuthylazine
def: "The (<i>S</i>)-enantiomer of <em>N</em>-(butan-2-yl)-6-chloro-<em>N</em>'-ethyl-1,3,5-triazine-2,4-diamine." []
is_a: CHEBI:83789 ! N-(butan-2-yl)-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine

[Term]
id: CHEBI:83804
name: 3-\{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl\}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
def: "A member of the class of pyridopyrimidines that is 9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-<em>a</em>]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2." []
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38932 ! pyridopyrimidine
is_a: CHEBI:48585 ! heteroarylpiperidine
is_a: CHEBI:51545 ! 1,2-benzoxazoles

[Term]
id: CHEBI:83805
name: (S)-paliperidone
def: "A 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-<em>a</em>]pyrimidin-4-one that is the (<i>S</i>)-enantiomer of paliperidone." []
is_a: CHEBI:83804 ! 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
relationship: RO:0018039 CHEBI:83806 ! is enantiomer of (R)-paliperidone

[Term]
id: CHEBI:83806
name: (R)-paliperidone
def: "A 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-<em>a</em>]pyrimidin-4-one that is the (<i>R</i>)-enantiomer of paliperidone." []
is_a: CHEBI:83804 ! 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
relationship: RO:0018039 CHEBI:83805 ! is enantiomer of (S)-paliperidone

[Term]
id: CHEBI:83807
name: paliperidone palmitate
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-paliperidone palmitate. A long-acting injectable formulation of paliperidone (the major active metabolite of risperidone) that is used for treatment of schizophrenia." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:83809 ! has part (S)-paliperidone palmitate
relationship: BFO:0000051 CHEBI:83810 ! has part (R)-paliperidone palmitate
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0000087 CHEBI:37955 ! has role H1-receptor antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic

[Term]
id: CHEBI:83808
name: 3-\{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl\}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl hexadecanoate
def: "A fatty acid ester obtained by the formal condensation of the carboxy group of hexadecanoic acid with the hydroxy group of 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-<em>a</em>]pyrimidin-4-one." []
is_a: CHEBI:35748 ! fatty acid ester
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38932 ! pyridopyrimidine
is_a: CHEBI:48585 ! heteroarylpiperidine
is_a: CHEBI:51545 ! 1,2-benzoxazoles

[Term]
id: CHEBI:83809
name: (S)-paliperidone palmitate
def: "A 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-<em>a</em>]pyrimidin-9-yl hexadecanoate that is the (<i>S</i>)-enantiomer of paliperidone palmitate." []
is_a: CHEBI:83808 ! 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl hexadecanoate
relationship: RO:0018039 CHEBI:83810 ! is enantiomer of (R)-paliperidone palmitate

[Term]
id: CHEBI:83810
name: (R)-paliperidone palmitate
def: "A 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-<em>a</em>]pyrimidin-9-yl hexadecanoate that is the (<i>R</i>)-enantiomer of paliperidone palmitate." []
is_a: CHEBI:83808 ! 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl hexadecanoate
relationship: RO:0018039 CHEBI:83809 ! is enantiomer of (S)-paliperidone palmitate

[Term]
id: CHEBI:83811
name: proteinogenic amino acid derivative
def: "Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom." []
is_a: CHEBI:83821 ! amino-acid derivative
relationship: RO:0018038 CHEBI:83813 ! has functional parent proteinogenic amino acid

[Term]
id: CHEBI:83812
name: non-proteinogenic amino acid derivative
def: "Any derivative of a non-proteinogenic amino acid resulting from reaction at an amino group or carboxy group, or from the replacement of any hydrogen by a heteroatom." []
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:83813
name: proteinogenic amino acid
def: "Any of the 23 α-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and <em>N</em>-formylmethionine. Apart from glycine, which is non-chiral, all have <small>L</small> configuration." []
is_a: CHEBI:33709 ! amino acid

[Term]
id: CHEBI:83814
name: fluorotelomer
def: "Any organofluorine compound that is a oligomer or telomer synthesised by telomerization (a chain transfer reaction to produce an oligomer of a limited size). They are generally used in fire-fighting foams, leather protectants, food packaging and stain resistants." []
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:83818
name: morphinane-like compound
def: "Any organonitrogen heterocyclic compound based on a morphinan skeleton. These are synthetic or semi-synthetic compounds that resemble the  morphinane (opioid) alkaloids in their pharmacological effects." []
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:8382
name: prednisone
def: "A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a β-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:47787 ! 11-oxo steroid
is_a: CHEBI:61313 ! C21-steroid
is_a: CHEBI:77166 ! 3-oxo-Delta(1),Delta(4)-steroid
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:37962 ! has role adrenergic agent
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent

[Term]
id: CHEBI:83820
name: non-proteinogenic amino acid
def: "Any amino-acid that is not naturally encoded in the genetic code of any organism." []
is_a: CHEBI:33709 ! amino acid

[Term]
id: CHEBI:83821
name: amino-acid derivative
def: "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." []
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:83822
name: non-proteinogenic L-alpha-amino acid
def: "Any <small>L</small>-α-amino acid which is not a member of the group of 23 proteinogenic amino acids." []
is_a: CHEBI:15705 ! L-alpha-amino acid
is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid

[Term]
id: CHEBI:83824
name: L-cysteine derivative
def: "A proteinogenic amino acid derivative resulting from the formal reaction of <small>L</small>-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of <small>L</small>-cysteine by a heteroatom." []
is_a: CHEBI:23509 ! cysteine derivative
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:17561 ! has functional parent L-cysteine

[Term]
id: CHEBI:83829
name: 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole
def: "A member of the class of imidazoles in which the hydrogen at position 1 is replaced by a 2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:25698 ! ether

[Term]
id: CHEBI:83830
name: (S)-enilconazole
def: "A 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that is the (<i>S</i>)-enantiomer of enilconazole" []
is_a: CHEBI:83829 ! 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole
relationship: RO:0018039 CHEBI:83831 ! is enantiomer of (R)-enilconazole

[Term]
id: CHEBI:83831
name: (R)-enilconazole
def: "A 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that is the (<i>R</i>)-enantiomer of enilconazole." []
is_a: CHEBI:83829 ! 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole
relationship: RO:0018039 CHEBI:83830 ! is enantiomer of (S)-enilconazole

[Term]
id: CHEBI:8386
name: pregnane
is_a: CHEBI:35508 ! steroid fundamental parent

[Term]
id: CHEBI:83876
name: cationic sphingoid
def: "An organic cation obtained by protonation of the amino function of any sphingoid" []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:35785 ! is protonated form of sphingoid

[Term]
id: CHEBI:8389
name: estrone sodium sulfate
is_a: CHEBI:16158 ! steroid sulfate
is_a: CHEBI:35789 ! oxo steroid
is_a: CHEBI:38700 ! organic sodium salt
relationship: RO:0018038 CHEBI:17263 ! has functional parent estrone

[Term]
id: CHEBI:83925
name: non-proteinogenic alpha-amino acid
def: "Any  α-amino acid which is not a member of the group of 23 proteinogenic amino acids." []
is_a: CHEBI:33704 ! alpha-amino acid
is_a: CHEBI:83820 ! non-proteinogenic amino acid

[Term]
id: CHEBI:83943
name: L-alanine derivative
def: "A proteinogenic amino acid derivative resulting from reaction of <small>L</small>-alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>L</small>-alanine by a heteroatom." []
is_a: CHEBI:22278 ! alanine derivative
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:16977 ! has functional parent L-alanine

[Term]
id: CHEBI:83944
name: D-alanine derivative
def: "A non-proteinogenic amino acid derivative resulting from reaction of <small>D</small>-alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>D</small>-alanine by a heteroatom." []
is_a: CHEBI:22278 ! alanine derivative
is_a: CHEBI:83812 ! non-proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:15570 ! has functional parent D-alanine

[Term]
id: CHEBI:83955
name: 2-saturated fatty acid anion
def: "A fatty acid anion obtained by deprotonation of the carboxy group of any 2-saturated fatty acid." []
is_a: CHEBI:28868 ! fatty acid anion

[Term]
id: CHEBI:83970
name: cardiac glycoside
def: "Steroid lactones containing sugar residues that act on the contractile force of the cardiac muscles." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24400 ! glycoside
is_a: CHEBI:26766 ! steroid lactone
relationship: RO:0000087 CHEBI:77307 ! has role cardioprotective agent

[Term]
id: CHEBI:83972
name: 3-methyl fatty acid anion
def: "A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 3-methyl fatty acid; major species at pH 7.3." []
is_a: CHEBI:67013 ! methyl-branched fatty acid anion

[Term]
id: CHEBI:83976
name: 2-methyl fatty acid anion
def: "A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 2-methyl fatty acid; major species at pH 7.3." []
is_a: CHEBI:67013 ! methyl-branched fatty acid anion

[Term]
id: CHEBI:83982
name: L-glutamic acid derivative
def: "A proteinogenic amino acid derivative resulting from reaction of <small>L</small>-glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen of <small>L</small>-glutamic acid by a heteroatom." []
is_a: CHEBI:24315 ! glutamic acid derivative
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:16015 ! has functional parent L-glutamic acid

[Term]
id: CHEBI:83986
name: ethylenebis(dithiocarbamic acid)
def: "A dithiocarbamic acid resulting from the formal addition of a molecule of carbon disulfide to each amino group of ethylenediamine." []
is_a: CHEBI:78787 ! dithiocarbamic acids
relationship: RO:0018034 CHEBI:77308 ! is protonated form of ethylenebis(dithiocarbamate)
relationship: RO:0018038 CHEBI:30347 ! has functional parent ethylenediamine

[Term]
id: CHEBI:83991
name: imidothioate
def: "A compound with the general formula R'-N=C(SR)R'' where R is organyl and R' and R'' can be organyl or H." []
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:35352 ! organonitrogen compound

[Term]
id: CHEBI:84002
name: 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one
def: "A member of the class of triazoles that is 1-hydroxy-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one in which the hydroxyl hydrogen is replaced by a 4-chlorophenyl group." []
is_a: CHEBI:141498 ! hemiaminal ether
is_a: CHEBI:17087 ! ketone
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:83403 ! monochlorobenzenes

[Term]
id: CHEBI:84003
name: (R)-triadimefon
def: "A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (<i>R</i>)-enantiomer of triadimefon." []
is_a: CHEBI:84002 ! 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one
relationship: RO:0018039 CHEBI:84004 ! is enantiomer of (S)-triadimefon

[Term]
id: CHEBI:84004
name: (S)-triadimefon
def: "A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (<i>S</i>)-enantiomer of triadimefon." []
is_a: CHEBI:84002 ! 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one
relationship: RO:0018039 CHEBI:84003 ! is enantiomer of (R)-triadimefon

[Term]
id: CHEBI:84043
name: gallium(3+)
def: "A monoatomic trication derived from gallium." []
is_a: CHEBI:231855 ! gallium cation
is_a: CHEBI:27153 ! monoatomic trication

[Term]
id: CHEBI:8405
name: primaquine
def: "An <em>N</em>-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N<small><sup>4</small></sup> position. It is a drug used in the treatment of malaria and <em>Pneumocystis</em> pneumonia." []
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36709 ! aminoquinoline
is_a: CHEBI:50441 ! N-substituted diamine
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent

[Term]
id: CHEBI:84055
name: pentose phosphate
def: "Any phospho sugar that is the phosphate derivative of pentose." []
is_a: CHEBI:33447 ! phospho sugar
is_a: CHEBI:63409 ! pentose derivative

[Term]
id: CHEBI:84069
name: pentanal
def: "A saturated fatty aldehyde composed from five carbons in a straight chain." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:133249 ! saturated fatty aldehyde
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:84087
name: human urinary metabolite
def: "Any metabolite (endogenous or exogenous) found in human urine samples." []
is_a: CHEBI:77746 ! human metabolite

[Term]
id: CHEBI:8412
name: primidone
def: "A pyrimidone that is dihydropyrimidine-4,6(1<em>H</em>,5<em>H</em>)-dione substituted by an ethyl and a phenyl group at position 5. It is used as an  anticonvulsant for treatment of various types of seizures." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38337 ! pyrimidone
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:84124
name: D-tyrosine derivative
def: "A non-proteinogenic amino acid derivative resulting from reaction of <small>D</small>-tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>D</small>-tyrosine by a heteroatom." []
is_a: CHEBI:62761 ! tyrosine derivative
is_a: CHEBI:84143 ! D-phenylalanine derivative
relationship: RO:0018038 CHEBI:28479 ! has functional parent D-tyrosine

[Term]
id: CHEBI:84129
name: L-valine derivative
def: "A proteinogenic amino acid derivative resulting from reaction of <small>L</small>-valine at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>L</small>-valine by a heteroatom." []
is_a: CHEBI:27267 ! valine derivative
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:16414 ! has functional parent L-valine

[Term]
id: CHEBI:84143
name: D-phenylalanine derivative
def: "A non-proteinogenic amino acid derivative resulting from reaction of <small>D</small>-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>D</small>-phenylalanine by a heteroatom." []
is_a: CHEBI:25985 ! phenylalanine derivative
is_a: CHEBI:83812 ! non-proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:16998 ! has functional parent D-phenylalanine

[Term]
id: CHEBI:84144
name: L-phenylalanine derivative
def: "A proteinogenic amino acid derivative resulting from reaction of <small>L</small>-phenylalanine  at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>L</small>-phenylalanine  by a heteroatom." []
is_a: CHEBI:25985 ! phenylalanine derivative
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:17295 ! has functional parent L-phenylalanine

[Term]
id: CHEBI:84186
name: L-proline derivative
def: "A proteinogenic amino acid derivative resulting from reaction of <small>L</small>-proline at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>L</small>-proline  by a heteroatom." []
is_a: CHEBI:26273 ! proline derivative
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:17203 ! has functional parent L-proline

[Term]
id: CHEBI:84189
name: L-threonine derivative
def: "A proteinogenic amino acid derivative resulting from reaction of <small>L</small>-threonine  at the amino group or the carboxy group, or from the replacement of any hydrogen of <small>L</small>-threonine  by a heteroatom." []
is_a: CHEBI:26987 ! threonine derivative
is_a: CHEBI:83811 ! proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:16857 ! has functional parent L-threonine

[Term]
id: CHEBI:84192
name: teixobactin
def: "A cyclodepsipeptide that is isolated from the previously unculturable bacterial species <em>Eleftheria terrae</em> and is active against gram-positive bacteria." []
is_a: CHEBI:25903 ! peptide antibiotic
is_a: CHEBI:35213 ! cyclodepsipeptide
is_a: CHEBI:51026 ! macrocycle
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent

[Term]
id: CHEBI:84199
name: quinmerac
def: "A quinolinemonocarboxylic acid that is quinoline-8-carboxylic acid carrying additional methyl and chloro substituents at positions 3 and 7 respectively. A residual herbicide used to control broad-leaved weeds on a range of crops including cereals, rape and beet." []
is_a: CHEBI:26512 ! quinolinemonocarboxylic acid
is_a: CHEBI:36683 ! organochlorine compound
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:26841 ! has role synthetic auxin
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:84254
name: N,N-dimethylacetamide
def: "A member of the class of  acetamides that is  acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:29347 ! monocarboxylic acid amide
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018038 CHEBI:27856 ! has functional parent acetamide

[Term]
id: CHEBI:84264
name: EC 3.5.1.19 (nicotinamidase) inhibitor
def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19)." []
is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor

[Term]
id: CHEBI:8427
name: probucol
def: "A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:38976 ! alkylbenzene
is_a: CHEBI:59800 ! dithioketal
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug

[Term]
id: CHEBI:84276
name: methyl phenyl(piperidin-2-yl)acetate
def: "A amino acid ester that is methyl phenylacetate in which one of the hydrogens α to the carbonyl group is replaced by a piperidin-2-yl group." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:85139 ! beta-amino acid ester

[Term]
id: CHEBI:84291
name: organic sulfur anion
def: "An organic anion in which the charge resides on a sulfur atom." []
is_a: CHEBI:25696 ! organic anion
is_a: CHEBI:26835 ! sulfur molecular entity

[Term]
id: CHEBI:84292
name: dithiocarbamate anions
def: "Any organic sulfur anion resulting from the removal of a proton from any <em>N</em>-substituted dithiocarbamic acid." []
is_a: CHEBI:84291 ! organic sulfur anion
relationship: RO:0018033 CHEBI:78787 ! is deprotonated form of dithiocarbamic acids

[Term]
id: CHEBI:84293
name: dimethyldithiocarbamate
def: "A member of the class of dithiocarbamate anions resulting from the removal of the proton from the dithiocarbamic acid moiety of dimethyldithiocarbamic acid. The major species at pH 7.3." []
is_a: CHEBI:84292 ! dithiocarbamate anions
relationship: RO:0018033 CHEBI:83061 ! is deprotonated form of dimethyldithiocarbamic acid

[Term]
id: CHEBI:8434
name: prochloraz
def: "A member of the class of ureas that is 1<em>H</em>-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables." []
is_a: CHEBI:27096 ! trichlorobenzene
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:47857 ! ureas
is_a: CHEBI:60600 ! amide fungicide
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87068 ! imidazole fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:84410
name: sphingoid base(1+)
def: "A cationic sphingoid obtained by protonation of the amino group of any 2-amino-1,3-dihydroxysphingoid base." []
is_a: CHEBI:35785 ! sphingoid
is_a: CHEBI:83876 ! cationic sphingoid

[Term]
id: CHEBI:84415
name: acetyltaurine
def: "An amino sulfonic acid that is taurine substituted by an acetyl group at the N atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:33551 ! organosulfonic acid
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018034 CHEBI:133737 ! is protonated form of acetyltaurine(1-)
relationship: RO:0018038 CHEBI:15891 ! has functional parent taurine

[Term]
id: CHEBI:84491
name: poly(I:C)
def: "A mismatched double-stranded RNA with one strand being a polymer of inosinic acid, the other a polymer of cytidylic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:67208 ! double-stranded RNA
relationship: BFO:0000051 CHEBI:76777 ! has part poly(inosinic acid)
relationship: BFO:0000051 CHEBI:84498 ! has part poly(cytidylic acid)
relationship: RO:0000087 CHEBI:50847 ! has role immunological adjuvant

[Term]
id: CHEBI:84498
name: poly(cytidylic acid)
def: "A polynucleotide comprised of cytidine units connected via 3'→5' phosphodiester linkages." []
is_a: CHEBI:15986 ! polynucleotide
relationship: BFO:0000051 CHEBI:50308 ! has part cytidine 5'-monophosphate residue

[Term]
id: CHEBI:84500
name: varenicline
def: "An organic heterotetracyclic compound that acts as a partial agonist for nicotinic cholinergic receptors and is used (in the form of its tartate salt) as an aid to giving up smoking." []
is_a: CHEBI:35990 ! bridged compound
is_a: CHEBI:38163 ! organic heterotetracyclic compound
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:35941 ! has role serotonergic agonist
relationship: RO:0000087 CHEBI:47958 ! has role nicotinic acetylcholine receptor agonist
relationship: RO:0018033 CHEBI:84508 ! is deprotonated form of varenicline(1+)

[Term]
id: CHEBI:84508
name: varenicline(1+)
def: "An organic cation obtained by protonation of the secondary amino group of varenicline." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:84500 ! is protonated form of varenicline

[Term]
id: CHEBI:84561
name: 2,4-dinitrophenol(1-)
def: "A phenolate anion obtained from 2,4-dinitrophenol. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0000087 CHEBI:76976 ! has role bacterial xenobiotic metabolite
relationship: RO:0018033 CHEBI:42017 ! is deprotonated form of 2,4-dinitrophenol

[Term]
id: CHEBI:84698
name: bromochlorodifluoromethane
def: "A one-carbon compound that is methane in which the hydrogens have been replaced by two fluorines, a bromine, and a chlorine. Widely used in 'vapourising liquid'-type fire extinguishers, its use is now generally banned under the Montreal Protocol (ozone-depleting substances), although it is still used in certain applications (e.g. aviation)." []
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37141 ! organobromine compound
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:64708 ! one-carbon compound

[Term]
id: CHEBI:84729
name: hydroxyindoles
def: "Any member of the class of  indoles carrying at least one hydroxy group." []
is_a: CHEBI:24828 ! indoles
is_a: CHEBI:33822 ! organic hydroxy compound

[Term]
id: CHEBI:8473
name: propane-1-thiol
def: "An alkanethiol that is propane substituted by a thiol group at position 1." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47908 ! alkanethiol
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:84735
name: algal metabolite
def: "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." []
is_a: CHEBI:75763 ! eukaryotic metabolite

[Term]
id: CHEBI:84745
name: amiloride(1+)
def: "An organic cation obtained by protonation of amiloride." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:2639 ! is protonated form of amiloride

[Term]
id: CHEBI:84771
name: nitroguanidine derivative
def: "Any <em>N</em>-nitro compound obtained by formal replacement of one or more of the hydrogens of a nitroguanidine by an organyl group." []
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:38780 ! N-nitro compound

[Term]
id: CHEBI:84773
name: 2-nitroguanidine derivative
def: "Any nitroguanidine derivative resulting from the replacement of one or more hydrogens of 2-nitroguanidine by an organyl group." []
is_a: CHEBI:84771 ! nitroguanidine derivative
relationship: RO:0018038 CHEBI:39181 ! has functional parent 2-nitroguanidine

[Term]
id: CHEBI:84799
name: EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor
def: "An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of arylamine <em>N</em>-acetyltransferase (EC 2.3.1.5)." []
is_a: CHEBI:76878 ! EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor

[Term]
id: CHEBI:84800
name: EC 2.4.1.1 (glycogen phosphorylase) inhibitor
def: "Any EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of glycogen phosphorylase (EC 2.4.1.1)." []
is_a: CHEBI:76789 ! EC 2.4.1.* (hexosyltransferase) inhibitor

[Term]
id: CHEBI:84801
name: EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor
def: "Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-trisphosphate 3-kinase (EC 2.7.1.127)." []
is_a: CHEBI:76881 ! EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor

[Term]
id: CHEBI:84802
name: EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor
def: "Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-polyphosphate multikinase (EC 2.7.1.151)." []
is_a: CHEBI:76881 ! EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor

[Term]
id: CHEBI:84803
name: EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor
def: "Any EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with a phosphate group as acceptor (EC 2.7.4.*)." []
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:84804
name: EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor
def: "Any EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor that interferes with the action of nucleoside-diphosphate kinase (EC 2.7.4.6)." []
is_a: CHEBI:84803 ! EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor

[Term]
id: CHEBI:8489
name: propiconazole
def: "The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1<em>H</em>-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:59779 ! cyclic ketal
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:84973
name: oleoyl-sn-glycero-3-phosphate(2-)
def: "A lysophosphatidate 18:1 in which the acyl group is specified as oleoyl (attached at either <em>sn</em>-1 or <em>sn</em>-2 position)." []
is_a: CHEBI:78279 ! lysophosphatidate 18:1

[Term]
id: CHEBI:8499
name: propranolol
def: "A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:32863 ! secondary amine
is_a: CHEBI:35533 ! propanolamine
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35530 ! has role beta-adrenergic antagonist
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:50646 ! has role bone density conservation agent
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66980 ! has role nootropic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76916 ! has role hyperglycemic agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:85234 ! has role human blood serum metabolite
relationship: RO:0018038 CHEBI:10319 ! has functional parent 1-naphthol

[Term]
id: CHEBI:8500
name: propranolol hydrochloride
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:8499 ! has part propranolol
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug

[Term]
id: CHEBI:8502
name: 6-propyl-2-thiouracil
def: "A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:48546 ! pyrimidinethione
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35221 ! has role antimetabolite
relationship: RO:0000087 CHEBI:50671 ! has role antithyroid drug
relationship: RO:0000087 CHEBI:50903 ! has role carcinogenic agent
relationship: RO:0000087 CHEBI:61908 ! has role EC 1.14.13.39 (nitric oxide synthase) inhibitor
relationship: RO:0000087 CHEBI:74529 ! has role antidote to paracetamol poisoning
relationship: RO:0018038 CHEBI:17568 ! has functional parent uracil

[Term]
id: CHEBI:8504
name: prostanoic acid
def: "A carbocyclic fatty acid composed of heptanoic acid having a (1<i>S</i>,2<i>S</i>)-2-octylcyclopentyl substituent at position 7." []
is_a: CHEBI:15904 ! long-chain fatty acid
is_a: CHEBI:26607 ! saturated fatty acid
is_a: CHEBI:35744 ! carbocyclic fatty acid

[Term]
id: CHEBI:85046
name: skin lightening agent
def: "Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin." []
is_a: CHEBI:64857 ! cosmetic

[Term]
id: CHEBI:85048
name: EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor
def: "An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.10.3.*)." []
is_a: CHEBI:76737 ! EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor

[Term]
id: CHEBI:85049
name: EC 1.10.3.1 (catechol oxidase) inhibitor
def: "Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of catechol oxidase (EC 1.10.3.1)." []
is_a: CHEBI:85048 ! EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor

[Term]
id: CHEBI:85050
name: EC 1.10.3.2 (laccase) inhibitor
def: "Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of laccase (EC 1.10.3.2)." []
is_a: CHEBI:85048 ! EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor

[Term]
id: CHEBI:85051
name: EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor
def: "Any EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 <em>O</em> atoms) inhibitor that interferes with the action of quercetin 2,3-dioxygenase (EC 1.13.1.24)." []
is_a: CHEBI:76837 ! EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor

[Term]
id: CHEBI:85052
name: EC 1.4.3.3 (D-amino-acid oxidase) inhibitor
def: "Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH<small><sub>2</sub></small> group, oxygen as acceptor) inhibitor that interferes with the action of <small>D</small>-amino-acid oxidase (EC 1.4.3.3)." []
is_a: CHEBI:76861 ! EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor

[Term]
id: CHEBI:85122
name: paraben
def: "A 4-hydroxybenzoate ester in which the esterifying alcohol is an alkanol (in diagram, R = alkyl). Commonly used as preservatives in cosmetic and pharmaceutical products." []
is_a: CHEBI:79323 ! 4-hydroxybenzoate ester

[Term]
id: CHEBI:85139
name: beta-amino acid ester
def: "An amino acid ester resulting from the formal condensation of the carboxy group of a β-amino acid with the hydroxy group of an alcohol or phenol." []
is_a: CHEBI:46668 ! amino-acid ester
is_a: CHEBI:83812 ! non-proteinogenic amino acid derivative
relationship: RO:0018038 CHEBI:33706 ! has functional parent beta-amino acid

[Term]
id: CHEBI:85164
name: nintedanib
def: "A member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:38459 ! oxindoles
is_a: CHEBI:46845 ! N-alkylpiperazine
is_a: CHEBI:46867 ! indolyl carboxylic acid
is_a: CHEBI:47989 ! enamine
is_a: CHEBI:62732 ! aromatic ester
is_a: CHEBI:62733 ! aromatic amide
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38637 ! has role tyrosine kinase inhibitor
relationship: RO:0000087 CHEBI:48422 ! has role angiogenesis inhibitor
relationship: RO:0000087 CHEBI:63457 ! has role fibroblast growth factor receptor antagonist
relationship: RO:0000087 CHEBI:65207 ! has role vascular endothelial growth factor receptor antagonist
relationship: RO:0018033 CHEBI:85172 ! is deprotonated form of nintedanib(1+)

[Term]
id: CHEBI:85172
name: nintedanib(1+)
def: "An organic cation obtained by protonation of nintedanib." []
is_a: CHEBI:25697 ! organic cation
relationship: RO:0018034 CHEBI:85164 ! is protonated form of nintedanib

[Term]
id: CHEBI:85184
name: dihydroxycholanic acid
def: "Any member of the class of cholanic acids carrying two hydroxy substituents at unspecified positions." []
is_a: CHEBI:33822 ! organic hydroxy compound
is_a: CHEBI:36278 ! cholanic acids

[Term]
id: CHEBI:85234
name: human blood serum metabolite
def: "Any metabolite (endogenous or exogenous) found in human blood serum samples." []
is_a: CHEBI:77746 ! human metabolite

[Term]
id: CHEBI:85259
name: diethylamine
def: "A secondary aliphatic amine where both <em>N</em>-substituents are ethyl." []
is_a: CHEBI:50981 ! secondary aliphatic amine
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0018033 CHEBI:132181 ! is deprotonated form of diethylammonium

[Term]
id: CHEBI:85267
name: flumequine
def: "A racemate comprising equimolar amounts of <i>R</i>- and <i>S</i>-flumequine. A broad-spectrum antibiotic, formerly used in veterinary medicine for stock breeding and treatment of aquacultures." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:85272 ! has part (S)-flumequine
relationship: BFO:0000051 CHEBI:85273 ! has part (R)-flumequine
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50750 ! has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0000087 CHEBI:53559 ! has role topoisomerase IV inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:85269
name: 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
def: "A member of the class of pyridoquinolines that is 1-oxo-6,7-dihydro-1<em>H</em>,5<em>H</em>-pyrido[3,2,1-<em>ij</em>]quinoline carrying additional carboxy, methyl and fluoro substituents at positions 2, 5 and 9 respectively." []
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38921 ! pyridoquinoline
is_a: CHEBI:47881 ! 3-oxo monocarboxylic acid
is_a: CHEBI:86324 ! quinolone antibiotic

[Term]
id: CHEBI:85272
name: (S)-flumequine
def: "A 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1<em>H</em>,5<em>H</em>-pyrido[3,2,1-<em>ij</em>]quinoline-2-carboxylic acid that is the (<i>S</i>)-enantiomer of flumequine." []
is_a: CHEBI:85269 ! 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
relationship: RO:0018039 CHEBI:85273 ! is enantiomer of (R)-flumequine

[Term]
id: CHEBI:85273
name: (R)-flumequine
def: "A 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1<em>H</em>,5<em>H</em>-pyrido[3,2,1-<em>ij</em>]quinoline-2-carboxylic acid that is the (<i>R</i>)-enantiomer of flumequine." []
is_a: CHEBI:85269 ! 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
relationship: RO:0018039 CHEBI:85272 ! is enantiomer of (S)-flumequine

[Term]
id: CHEBI:85278
name: 17beta-hydroxyandrostan-3-one
def: "A 17β-hydroxy steroid that is testosterone in which the 4-5 double bond has been reduced to a single bond with unspecified configuration at position 5." []
is_a: CHEBI:35343 ! 17beta-hydroxy steroid
is_a: CHEBI:47788 ! 3-oxo steroid
relationship: RO:0018040 CHEBI:35509 ! has parent hydride androstane

[Term]
id: CHEBI:85425
name: glycine transporter inhibitor
def: "Any substance that inhibits the action of glycine transporters." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:855
name: 2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol
def: "A member of the class of  triazoles that is 1-phenyl-1<em>H</em>-1,2,4-triazole substituted by 2-hydroxyphenyl groups at positions 3 and 5." []
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:35727 ! triazoles
relationship: RO:0018040 CHEBI:38967 ! has parent hydride 1-phenyl-1H-1,2,4-triazole

[Term]
id: CHEBI:85541
name: elemental bismuth
is_a: CHEBI:33259 ! elemental molecular entity
is_a: CHEBI:37196 ! bismuth molecular entity

[Term]
id: CHEBI:85543
name: bismuth ion
def: "A bismuth atom having a net electric charge." []
is_a: CHEBI:36914 ! inorganic ion
is_a: CHEBI:85541 ! elemental bismuth

[Term]
id: CHEBI:85572
name: Ku-0063794
def: "A member of the class of pyridopyrimidines that is an mTOR inhibitor and shows anti-tumour properties." []
is_a: CHEBI:22743 ! benzyl alcohols
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:38932 ! pyridopyrimidine
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:68481 ! has role mTOR inhibitor

[Term]
id: CHEBI:85638
name: haloacetate(1-)
def: "A monocarboxylic acid anion resulting from the deprotonation of the carboxy group of a haloacetic acid." []
is_a: CHEBI:35757 ! monocarboxylic acid anion
relationship: RO:0018033 CHEBI:16277 ! is deprotonated form of haloacetic acid
relationship: RO:0018038 CHEBI:30089 ! has functional parent acetate

[Term]
id: CHEBI:85782
name: heptachlorobiphenyl
def: "Any polychlorobiphenyl with molecular formula C<small><sub>12</sub></small>H<small><sub>3</sub></small>Cl<small><sub>7</sub></small>." []
is_a: CHEBI:53156 ! polychlorobiphenyl

[Term]
id: CHEBI:85993
name: palbociclib
def: "A member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-<em>d</em>]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combination with letrozole for the treatment of metastatic breast cancer." []
is_a: CHEBI:23493 ! cyclopentanes
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:38207 ! aminopyridine
is_a: CHEBI:38932 ! pyridopyrimidine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:82665 ! has role EC 2.7.11.22 (cyclin-dependent kinase) inhibitor

[Term]
id: CHEBI:86264
name: rat metabolite
def: "Any mammalian metabolite produced during a metabolic reaction in rat (<em>Rattus norvegicus</em>)." []
is_a: CHEBI:75768 ! mammalian metabolite

[Term]
id: CHEBI:86297
name: picrate anion
def: "A phenolate anion resulting from deprotonation of the phenolic hydroxy group of picric acid." []
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0018033 CHEBI:46149 ! is deprotonated form of picric acid

[Term]
id: CHEBI:86315
name: methyl sulfide
def: "Any aliphatic sulfide in which at least one of the organyl groups attached to the sulfur is a methyl group." []
is_a: CHEBI:16385 ! organic sulfide

[Term]
id: CHEBI:86322
name: alkaloid antibiotic
def: "Any alkaloid that has significant antibiotic properties." []
is_a: CHEBI:22315 ! alkaloid
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:86323
name: conazole antifungal agent
def: "A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties.  They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:68452 ! azole
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:75282 ! has role ergosterol biosynthesis inhibitor

[Term]
id: CHEBI:86324
name: quinolone antibiotic
def: "An organonitrogen heterocyclic antibiotic whose structure contains a quinolone or quinolone-related skeleton." []
is_a: CHEBI:25558 ! organonitrogen heterocyclic antibiotic

[Term]
id: CHEBI:86327
name: antifungal drug
def: "Any antifungal agent used to prevent or treat fungal infections in humans or animals." []
is_a: CHEBI:35441 ! antiinfective agent
is_a: CHEBI:35718 ! antifungal agent

[Term]
id: CHEBI:86328
name: antifungal agrochemical
def: "Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties." []
is_a: CHEBI:24127 ! fungicide
is_a: CHEBI:33286 ! agrochemical

[Term]
id: CHEBI:8633
name: puerarin
def: "A hydroxyisoflavone that is  isoflavone substituted by hydroxy groups at positions 7 and 4' and a β-<small>D</small>-glucopyranosyl residue at position 8 via a <em>C</em>-glycosidic linkage." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:20857 ! C-glycosyl compound
is_a: CHEBI:38755 ! hydroxyisoflavone
relationship: RO:0000087 CHEBI:138880 ! has role autophagy inducer
relationship: RO:0000087 CHEBI:173084 ! has role ferroptosis inhibitor
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:35493 ! has role antipyretic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:77307 ! has role cardioprotective agent
relationship: RO:0018034 CHEBI:229573 ! is protonated form of puerarin(1-)
relationship: RO:0018038 CHEBI:18220 ! has functional parent isoflavone

[Term]
id: CHEBI:86349
name: N-carbamoylglutamic acid
def: "A glutamic acid derivative that is glutamic acid substituted by a carbamoyl group at the nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24315 ! glutamic acid derivative
is_a: CHEBI:47857 ! ureas
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:233559 ! is protonated form of N-carbamoylglutamate(2-)

[Term]
id: CHEBI:86383
name: EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor
def: "An EC 5.3.* (intramolecular oxidoreductase) inhibitor that inhibits the action of any such enzyme that transposes C=C bonds (EC 5.3.3.*)." []
is_a: CHEBI:76694 ! EC 5.3.* (intramolecular oxidoreductase) inhibitor

[Term]
id: CHEBI:86385
name: EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
def: "An EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor that interferes with the action of a cholestenol Δ-isomerase (EC 5.3.3.5)." []
is_a: CHEBI:86383 ! EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor

[Term]
id: CHEBI:86411
name: cis-1-acetyl-4-(4-\{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy\}phenyl)piperazine
def: "Either of the two diastereoisomers of 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1<em>H</em>-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the imidazol-1-ylmethyl group and the aryloxymethyl group are in a <i>cis</i> relationship to each other - i.e. they are both on the same side of the plane of the dioxolane ring. The antifungal drug ketoconazole is a racemic mixture of the two <i>cis</i> diastereoisomers." []
is_a: CHEBI:48339 ! 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine

[Term]
id: CHEBI:86417
name: aliphatic nitrogen antifungal agent
def: "Organonitrogen compounds containing an aliphatic nitrogen that have significant antifungal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:86420
name: imidazole antifungal agent
def: "A compound that has significant antifungal properties whose structure contains an imidazole moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24780 ! imidazoles
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:86421
name: 2-nitrophenols
def: "A mononitrophenol that is 2-nitrophenol and its derivatives resulting from substitution of one or more of the hydrogens attached to the benzene ring by a non-nitro group." []
is_a: CHEBI:39362 ! mononitrophenol

[Term]
id: CHEBI:86426
name: triazole antifungal agent
def: "A member of the class of triazole that has significant antifungal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35727 ! triazoles
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:86469
name: peptidoglycosaminoglycan
def: "A family of glycosaminoglycan formed by alternating residues of <small>D</small>-glucosamine and either muramic acid {2-amino-3-<em>O</em>-[(<i>S</i>)-1-carboxyethyl]-2-deoxy-<small>D</small>-glucose} or <small>L</small>-talosaminuronic acid (2-amino-2-deoxy-<small>L</small>-taluronic acid), which are usually <em>N</em>-acetylated or <em>N</em>-glycoloylated. Those containing muramic acid residues are known as peptidoglycans while those containing <small>L</small>-talosaminuronic acid residues are known as pseudopeptidoglycans. The carboxyl group of the muramic acid is commonly substituted by a peptide containing residues of both <small>L</small>- and <small>D</small>-amino acids, whereas that of <small>L</small>-talosaminuronic acid is substituted by a peptide consisting of <small>L</small>-amino acids only." []
is_a: CHEBI:18085 ! glycosaminoglycan

[Term]
id: CHEBI:86478
name: antibiotic antifungal agent
def: "Heteroorganic entities that are microbial metabolites (or compounds derived from them) which have significant antifungal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33285 ! heteroorganic entity
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:86482
name: strobilurin antifungal agent
def: "Any antibiotic antifungal agents whose structure is based on the antifungal agents originally isolated from the fungus <em>Strobilurus tenacellus</em>." []
is_a: CHEBI:86478 ! antibiotic antifungal agent

[Term]
id: CHEBI:86484
name: methoxyacrylate strobilurin antifungal agent
def: "Any strobilurin antifungal agent that contains a methoxyacrylate group." []
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:51702 ! enoate ester
is_a: CHEBI:86482 ! strobilurin antifungal agent

[Term]
id: CHEBI:86485
name: methoxycarbanilate strobilurin antifungal agent
def: "Any strobilurin antifungal agent that contains a methoxycarbanilate group." []
is_a: CHEBI:23003 ! carbamate ester
is_a: CHEBI:86482 ! strobilurin antifungal agent

[Term]
id: CHEBI:86488
name: methoxyiminoacetate strobilurin antifungal agent
def: "Any strobilurin antifungal agent that contains a methoxyiminoacetate group, RC(=NOMe)CO<small><sub>2</sub></small>Me." []
is_a: CHEBI:86482 ! strobilurin antifungal agent

[Term]
id: CHEBI:86494
name: botanical anti-fungal agent
def: "Heteroorganic entities that are plant metabolites which have significant antifungal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33285 ! heteroorganic entity
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:86511
name: 6H-dibenzo[b,d]pyran-6-one
def: "A benzochromenone that is 6<em>H</em>-dibenzo[<em>b,d</em>]pyran substituted by an oxo group at position 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:64986 ! benzochromenone
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:86564
name: 4-guanidinobutyric acid
def: "A monocarboxylic acid that is butanoic acid substituted by a guanidino group at position 4." []
is_a: CHEBI:24436 ! guanidines
is_a: CHEBI:25384 ! monocarboxylic acid

[Term]
id: CHEBI:86644
name: Gibberellic acid
is_a: CHEBI:20858 ! C19-gibberellin
is_a: CHEBI:38305 ! gibberellin monocarboxylic acid

[Term]
id: CHEBI:8666
name: Pyridostigmine bromide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38188 ! pyridinium salt
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50514 ! has role vasoconstrictor agent
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug

[Term]
id: CHEBI:8673
name: pyrimethamine
def: "An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a <em>p</em>-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis." []
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50683 ! has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:8674
name: pyrimethanil
def: "A member of the class of aminopyrimidines that is <em>N</em>-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6.  A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control <em>Botrytis cinerea</em> throughout the winemaking process in grapes, must, fermenting must and wine." []
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:87208 ! anilinopyrimidine fungicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:72768 ! has role aryl hydrocarbon receptor agonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:86969
name: loperamide(1+)
def: "An organic cation obtained by protonation of the tertiary amino function of loperamide." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:6532 ! is protonated form of loperamide

[Term]
id: CHEBI:86990
name: N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
def: "An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group." []
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:83565 ! (trifluoromethyl)benzenes

[Term]
id: CHEBI:86991
name: (R)-fluoxetine
def: "An <em>N</em>-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has <i>R</i> configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-fluoxetine]." []
is_a: CHEBI:86990 ! N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0018033 CHEBI:86993 ! is deprotonated form of (R)-fluoxetine(1+)
relationship: RO:0018039 CHEBI:86992 ! is enantiomer of (S)-fluoxetine

[Term]
id: CHEBI:86992
name: (S)-fluoxetine
def: "An <em>N</em>-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has <i>S</i> configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-fluoxetine]." []
is_a: CHEBI:86990 ! N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0018033 CHEBI:86995 ! is deprotonated form of (S)-fluoxetine(1+)
relationship: RO:0018039 CHEBI:86991 ! is enantiomer of (R)-fluoxetine

[Term]
id: CHEBI:86993
name: (R)-fluoxetine(1+)
def: "An organic cation resulting from the protonation of the amino group of (<i>R</i>)-fluoxetine." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:86991 ! is protonated form of (R)-fluoxetine
relationship: RO:0018039 CHEBI:86995 ! is enantiomer of (S)-fluoxetine(1+)

[Term]
id: CHEBI:86995
name: (S)-fluoxetine(1+)
def: "An organic cation resulting from the protonation of the amino group of (<i>S</i>)-fluoxetine." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:86992 ! is protonated form of (S)-fluoxetine
relationship: RO:0018039 CHEBI:86993 ! is enantiomer of (R)-fluoxetine(1+)

[Term]
id: CHEBI:87012
name: amide antifungal agent
def: "A compound that has significant antifungal properties whose structure contains an amide moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:87013
name: acylamino acid fungicide
def: "An amide fungicide whose structure contains an acylamino acid skeleton." []
is_a: CHEBI:60600 ! amide fungicide

[Term]
id: CHEBI:87015
name: anilide fungicide
def: "Any amide fungicide whose structure contains an anilide group." []
is_a: CHEBI:60600 ! amide fungicide

[Term]
id: CHEBI:87029
name: valinamide fungicide
def: "An amide fungicide whose structure contains a valine amide moiety." []
is_a: CHEBI:60600 ! amide fungicide
is_a: CHEBI:83821 ! amino-acid derivative

[Term]
id: CHEBI:87034
name: aromatic fungicide
def: "An organic aromatic compound that has been used as a fungicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33659 ! organic aromatic compound
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87036
name: benzimidazole fungicide
def: "Compounds that contain a benzimidazole moiety as a key feature of their structure and which have been used as fungicides." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22715 ! benzimidazoles
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87039
name: bridged diphenyl fungicide
def: "Any organic aromatic compound containing two phenyl (or substituted phenyl) groups attached to a single carbon or heteroatom and which has been used as a fungicide." []
is_a: CHEBI:60644 ! bridged diphenyl antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87061
name: carbamate fungicide
def: "Compounds that contain a carbamate ester moiety as a key feature of their structure and which have been used as fungicides." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23003 ! carbamate ester
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87064
name: benzimidazolylcarbamate fungicide
def: "Any carbamate fungicide that contains a benzimidazolyl group attached to the nitrogen of the carbamate moiety." []
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:87061 ! carbamate fungicide

[Term]
id: CHEBI:87066
name: carbanilate fungicide
def: "Any carbamate fungicide that has a phenyl or substituted-phenyl group attached to the nitrogen of the carbamate group." []
is_a: CHEBI:87061 ! carbamate fungicide

[Term]
id: CHEBI:87067
name: conazole fungicide
def: "Any conazole antifungal agent that has been used as a fungicide." []
is_a: CHEBI:86323 ! conazole antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87068
name: imidazole fungicide
def: "Any imidazole antifungal agent that has been used as a fungicide." []
is_a: CHEBI:86420 ! imidazole antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87069
name: imidazole antifungal drug
def: "Any imidazole antifungal agent that has been used for the treatment of fungal infections in humans or animals." []
is_a: CHEBI:86420 ! imidazole antifungal agent
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:8707
name: quetiapine
is_a: CHEBI:39268 ! dibenzothiazepine
is_a: CHEBI:46845 ! N-alkylpiperazine
is_a: CHEBI:46848 ! N-arylpiperazine
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:37887 ! has role adrenergic antagonist
relationship: RO:0000087 CHEBI:37956 ! has role histamine antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:50779 ! has role appetite enhancer
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic

[Term]
id: CHEBI:87071
name: conazole antifungal drug
def: "Any conazole antifungal agent that has been used for the treatment of fungal infections in animals or humans." []
is_a: CHEBI:86323 ! conazole antifungal agent
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:87094
name: acid red 4
def: "An organic sodium salt having 4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-1-sulfonate as the counterion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:87099 ! has part 4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-1-sulfonate
relationship: RO:0000087 CHEBI:37958 ! has role dye
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:87098
name: 4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-1-sulfonic acid
def: "A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid carrying additional hydroxy and (2-methoxyphenyl)diazenyl substituents at positions 4 and 3 respectively. The sodium salt is the biological stain 'acid red 4'." []
is_a: CHEBI:22682 ! azobenzenes
is_a: CHEBI:25392 ! naphthols
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:36336 ! naphthalenesulfonic acid
relationship: RO:0018034 CHEBI:87099 ! is protonated form of 4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-1-sulfonate

[Term]
id: CHEBI:87099
name: 4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-1-sulfonate
def: "An organosulfonate oxoanion obtained by deprotonation of the sulfo group of 4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-1-sulfonic acid." []
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:87098 ! is deprotonated form of 4-hydroxy-3-[(2-methoxyphenyl)diazenyl]naphthalene-1-sulfonic acid

[Term]
id: CHEBI:87100
name: triazole fungicide
def: "Any triazole antifungal agent that has been used as a fungicide." []
is_a: CHEBI:86426 ! triazole antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87101
name: triazole antifungal drug
def: "Any triazole antifungal agent that has been used for the treatment of fungal infections in humans or animals." []
is_a: CHEBI:86426 ! triazole antifungal agent
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:87113
name: antibiotic antifungal drug
def: "Any antibiotic antifungal agent used to treat fungal infections in humans or animals." []
is_a: CHEBI:86478 ! antibiotic antifungal agent
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:87114
name: antibiotic fungicide
def: "Any antibiotic antifungal agent that has been used as a fungicide." []
is_a: CHEBI:86478 ! antibiotic antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87127
name: allylamine antifungal drug
def: "An organonitrogen compound that contains an amino group that is attached to a carbon which is itself attached to an olefinic carbon and which has been used as an antifungal drug." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35352 ! organonitrogen compound
relationship: RO:0000087 CHEBI:86327 ! has role antifungal drug

[Term]
id: CHEBI:87132
name: morpholine antifungal agent
def: "A member of the class of morpholines that has significant antifungal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38785 ! morpholines
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:87134
name: morpholine fungicide
def: "Any morpholine antifungal agent used as a fungicide." []
is_a: CHEBI:87132 ! morpholine antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87183
name: STAT3 inhibitor
def: "An inhibitor of signal transducer and activator of transcription 3 (STAT3)" []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:87185
name: florfenicol
def: "A carboxamide that is the <em>N</em>-dichloroacetyl derivative of (1<i>R</i>,2<i>S</i>)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respiratory disease and foot rot; also used in aquaculture." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:33552 ! sulfonic acid derivative
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:35850 ! sulfone
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0018038 CHEBI:36386 ! has functional parent dichloroacetic acid

[Term]
id: CHEBI:87195
name: dicarboximide fungicide
def: "Any dicarboximide antifungal agent used as a fungicide." []
is_a: CHEBI:87200 ! dicarboximide antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87197
name: dichlorophenyl dicarboximide fungicide
def: "A dicarboximide fungicide in which the nitrogen of the dicarboximide group is substituted by a dichlorophenyl group." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:87195 ! dicarboximide fungicide

[Term]
id: CHEBI:87198
name: phthalimide fungicide
def: "A dicarboximide fungicide whose structure contains a phthalimide derivative." []
is_a: CHEBI:87195 ! dicarboximide fungicide

[Term]
id: CHEBI:87200
name: dicarboximide antifungal agent
def: "A compound that has significant antifungal properties whose structure contains a dicarboximide moiety." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35356 ! dicarboximide
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:87202
name: rose bengal free acid
def: "A xanthene dye that is fluorescein bearing bromine substituents at positions 2', 4', 5' and 7' (on the xanthene ring) and iodine substituents at position 2, 3, 4, and 5 (on the phenyl ring). The dipotassium salt is the biological stain 'rose bengal'." []
is_a: CHEBI:22723 ! benzoic acids
is_a: CHEBI:26888 ! tetrachlorobenzene
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:37929 ! xanthene dye
is_a: CHEBI:71971 ! neoflavonoid
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0018034 CHEBI:52904 ! is protonated form of rose bengal(2-)
relationship: RO:0018038 CHEBI:42492 ! has functional parent fluorescin

[Term]
id: CHEBI:87204
name: pyrimidine antifungal agent
def: "A member of the class of pyrimidines that has significant antifungal properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:39447 ! pyrimidines
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent

[Term]
id: CHEBI:87207
name: pyrimidine fungicide
def: "Any pyrimidine antifungal agent that has been used as a fungicide." []
is_a: CHEBI:87204 ! pyrimidine antifungal agent
relationship: RO:0000087 CHEBI:24127 ! has role fungicide

[Term]
id: CHEBI:87208
name: anilinopyrimidine fungicide
def: "Any pyrimidine fungicide in which the pyrimidine ring is substituted by the nitrogen of an aniline moiety." []
is_a: CHEBI:87207 ! pyrimidine fungicide

[Term]
id: CHEBI:87209
name: virginiamycin
def: "A mixture of cyclic polypeptide streptogramin antibiotics produced by <em>Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus,</em> and others. The two major components are virginiamycin M<small><sub>1</sub></small> (also known as  pristinamycin IIA) and virginiamycin S<small><sub>1</sub></small>. Virginiamycin has been widely used as a growth promotion agent in livestock and has been to have bacteriostatic activity against Gram-positive organisms such as staphylococci and streptococci." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60004 ! mixture
relationship: BFO:0000051 CHEBI:46416 ! has part virginiamycin S1
relationship: BFO:0000051 CHEBI:9997 ! has part pristinamycin IIA
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:87211
name: fluoroquinolone antibiotic
def: "An organonitrogen heterocyclic antibiotic containing a quinolone (or quinolone-like) moiety and which have a fluorine atom attached to the central ring system." []
is_a: CHEBI:25558 ! organonitrogen heterocyclic antibiotic
is_a: CHEBI:37143 ! organofluorine compound

[Term]
id: CHEBI:87228
name: sulfonamide antibiotic
def: "A class of sulfonamides whose members generally have bacteriostatic antibiotic properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35358 ! sulfonamide
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent

[Term]
id: CHEBI:87230
name: nitrofuran antibiotic
def: "A member of the class of furans in which the furan ring is substituted by a nitro group and which also has significant antibiotic properties." []
is_a: CHEBI:24129 ! furans
is_a: CHEBI:25558 ! organonitrogen heterocyclic antibiotic
is_a: CHEBI:25807 ! organooxygen heterocyclic antibiotic
is_a: CHEBI:35716 ! C-nitro compound

[Term]
id: CHEBI:8736
name: (R)-(+)-propranolol
is_a: CHEBI:8499 ! propranolol

[Term]
id: CHEBI:87362
name: pentyl acetate
def: "An acetate ester of pentanol." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:47622 ! acetate ester
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018038 CHEBI:44884 ! has functional parent pentan-1-ol

[Term]
id: CHEBI:8746
name: (R)-salbutamol
is_a: CHEBI:22743 ! benzyl alcohols
is_a: CHEBI:2549 ! albuterol

[Term]
id: CHEBI:87485
name: auramine O(1+)
is_a: CHEBI:35286 ! iminium ion
relationship: RO:0018034 CHEBI:51874 ! is protonated form of auramine O free base

[Term]
id: CHEBI:87518
name: ADP(2-)
def: "An organophosphate oxoanion obtained by deprotonation of two of the three diphosphate OH groups of adenosine 5'-diphosphate." []
is_a: CHEBI:58945 ! organophosphate oxoanion
relationship: RO:0018033 CHEBI:16761 ! is deprotonated form of ADP
relationship: RO:0018034 CHEBI:456216 ! is protonated form of ADP(3-)

[Term]
id: CHEBI:87631
name: statin
def: "Any organooxygen compound whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36963 ! organooxygen compound
relationship: RO:0000087 CHEBI:35664 ! has role EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
relationship: RO:0000087 CHEBI:35821 ! has role anticholesteremic drug

[Term]
id: CHEBI:87632
name: statin (naturally occurring)
def: "Any statin that occurs in nature. The class includes compactin (also known as mevastatin), isolated from a fermentation broth of <em>Penicillium citrinum</em>, and lovastatin, isolated from <em>Aspergillus terreus</em>." []
is_a: CHEBI:87631 ! statin
relationship: RO:0000087 CHEBI:25212 ! has role metabolite

[Term]
id: CHEBI:87633
name: statin (semi-synthetic)
def: "A statin that is derived from a naturally occurring statin by partial chemical synthesis." []
is_a: CHEBI:72588 ! semisynthetic derivative
is_a: CHEBI:87631 ! statin

[Term]
id: CHEBI:87635
name: statin (synthetic)
def: "A statin which does not occur naturally and which is not obtained by chemical transformation of a naturally occurring statin." []
is_a: CHEBI:87631 ! statin

[Term]
id: CHEBI:8764
name: mycophenolate mofetil
def: "A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases." []
is_a: CHEBI:25698 ! ether
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:37581 ! gamma-lactone
is_a: CHEBI:38831 ! 2-benzofurans
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35845 ! has role gout suppressant
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:50671 ! has role antithyroid drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:53746 ! has role EC 1.1.1.205 (IMP dehydrogenase) inhibitor
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:76595 ! has role nephroprotective agent
relationship: RO:0018038 CHEBI:168396 ! has functional parent mycophenolic acid
relationship: RO:0018038 CHEBI:67144 ! has functional parent 2-(morpholin-4-yl)ethanol

[Term]
id: CHEBI:87691
name: tetradecanoate ester
def: "A fatty acid ester obtained by condensation of the carboxy group of tetradecanoic acid (also known as myristic acid) with a hydroxy group of an alcohol or phenol." []
is_a: CHEBI:35748 ! fatty acid ester
relationship: RO:0018038 CHEBI:28875 ! has functional parent tetradecanoic acid

[Term]
id: CHEBI:87732
name: 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one
def: "A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group." []
is_a: CHEBI:22712 ! benzenes
is_a: CHEBI:37912 ! hydroxycoumarin
is_a: CHEBI:51867 ! methyl ketone

[Term]
id: CHEBI:87737
name: (R)-warfarin
def: "A 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2<em>H</em>-1-benzopyran-2-one that has (<i>R</i>)-configuration (the racemate is warfarin, an anticoagulant drug and rodenticide)." []
is_a: CHEBI:87732 ! 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one
relationship: RO:0018034 CHEBI:87743 ! is protonated form of (R)-warfarin(1-)
relationship: RO:0018039 CHEBI:87738 ! is enantiomer of (S)-warfarin

[Term]
id: CHEBI:87738
name: (S)-warfarin
def: "A 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2<em>H</em>-1-benzopyran-2-one that has (<i>S</i>)-configuration (the racemate is warfarin, an anticoagulant drug and rodenticide)." []
is_a: CHEBI:87732 ! 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one
relationship: RO:0018034 CHEBI:87744 ! is protonated form of (S)-warfarin(1-)
relationship: RO:0018039 CHEBI:87737 ! is enantiomer of (R)-warfarin

[Term]
id: CHEBI:87743
name: (R)-warfarin(1-)
def: "An organic anion that is the conjugate base of (<i>R</i>)-warfarin,  obtained by deprotonation of the hydroxy group." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:87737 ! is deprotonated form of (R)-warfarin
relationship: RO:0018039 CHEBI:87744 ! is enantiomer of (S)-warfarin(1-)

[Term]
id: CHEBI:87744
name: (S)-warfarin(1-)
def: "An organic anion that is the conjugate base of (<i>S</i>)-warfarin, obtained by deprotonation of the hydroxy group." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:87738 ! is deprotonated form of (S)-warfarin
relationship: RO:0018039 CHEBI:87743 ! is enantiomer of (R)-warfarin(1-)

[Term]
id: CHEBI:87751
name: ocimene
def: "A monoterpene based on an octatriene skeleton." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35187 ! monoterpene
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:87755
name: pentan-3-one
def: "A pentanone that is pentane carrying an oxo group at position 3. It has been isolated from  <em>Triatoma brasiliensis</em> and <em>Triatoma infestans</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25892 ! pentanone
relationship: RO:0000087 CHEBI:75767 ! has role animal metabolite

[Term]
id: CHEBI:8776
name: ranitidine
def: "A member of the class of  furans used to treat  peptic ulcer disease (PUD) and gastroesophageal reflux disease." []
is_a: CHEBI:16385 ! organic sulfide
is_a: CHEBI:24129 ! furans
is_a: CHEBI:35716 ! C-nitro compound
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:37961 ! has role H2-receptor antagonist
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen

[Term]
id: CHEBI:88048
name: cyanotoxin
def: "Any toxin produced by cyanobacteria (blue-green algae)." []
is_a: CHEBI:27026 ! toxin
is_a: CHEBI:76969 ! bacterial metabolite

[Term]
id: CHEBI:88061
name: polyamine
def: "Any organic amino compound that contains two or more amino groups." []
is_a: CHEBI:50047 ! organic amino compound

[Term]
id: CHEBI:8811
name: resmethrin
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24129 ! furans
is_a: CHEBI:50351 ! cyclopropanecarboxylate ester
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:39116 ! has role pyrethroid ester insecticide
relationship: RO:0018038 CHEBI:3680 ! has functional parent chrysanthemic acid

[Term]
id: CHEBI:88173
name: brilliant green
def: "An organic hydrogensulfate salt having 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-<em>N</em>,<em>N</em>-diethylcyclohexa-2,5-dien-1-iminium as the counterion." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:88175 ! organic hydrogensulfate salt
relationship: BFO:0000051 CHEBI:88176 ! has part brilliant green cation
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:64909 ! has role poison
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:88175
name: organic hydrogensulfate salt
def: "An organic salt containing hydrogensulfate as the anionic component." []
is_a: CHEBI:24868 ! organic salt
relationship: BFO:0000051 CHEBI:45696 ! has part hydrogensulfate

[Term]
id: CHEBI:88176
name: brilliant green cation
def: "An iminium ion that is the cationic component of the histological dye 'brilliant green'." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35286 ! iminium ion
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:64909 ! has role poison
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:88184
name: metal allergen
def: "Any metal which causes the onset of an allergic reaction." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:33521 ! metal atom
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:88186
name: metal cation allergen
def: "Any metal cation which causes the onset of an allergic reaction." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25213 ! metal cation
relationship: RO:0000087 CHEBI:50904 ! has role allergen

[Term]
id: CHEBI:88187
name: penicillin allergen
def: "Any penicillin which causes the onset of an allergic reaction." []
is_a: CHEBI:17334 ! penicillin

[Term]
id: CHEBI:88188
name: drug allergen
def: "Any drug which causes the onset of an allergic reaction." []
is_a: CHEBI:23888 ! drug
is_a: CHEBI:50904 ! allergen

[Term]
id: CHEBI:88190
name: 2-oxido-5-methylquinone
def: "An organic anion obtained by deprotonation of the hydroxy group of 2-hydroxy-5-methylquinone. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." []
is_a: CHEBI:25696 ! organic anion
relationship: RO:0018033 CHEBI:81667 ! is deprotonated form of 2-hydroxy-5-methylquinone

[Term]
id: CHEBI:88191
name: Sirius red 4B
def: "An organic sodium salt resulting from the formal condensation of Sirius red 4B (acid form) with two equivalents of sodium hydroxide. Used as the plasma stain in some trichrome staining methods." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:88193 ! has part Sirius red 4B(2-)
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:64909 ! has role poison
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:88192
name: Sirius red 4B (acid form)
def: "A naphthalenesulfonic acid that is 7-amino-4-hydroxy-3-({4-[(4-sulfophenyl)diazenyl]phenyl}diazenyl)naphthalene-2-sulfonic acid in which one of the amino hydrogens is replaced by a benzoyl group. The disodium salt is the histological dye 'Sirius red 4B'." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22682 ! azobenzenes
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:25392 ! naphthols
is_a: CHEBI:36336 ! naphthalenesulfonic acid
is_a: CHEBI:48960 ! bis(azo) compound
relationship: RO:0000087 CHEBI:51217 ! has role fluorochrome
relationship: RO:0000087 CHEBI:64909 ! has role poison
relationship: RO:0000087 CHEBI:77178 ! has role histological dye
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018034 CHEBI:88193 ! is protonated form of Sirius red 4B(2-)

[Term]
id: CHEBI:88193
name: Sirius red 4B(2-)
def: "An organosulfonate oxoanion obtained by deprotonation of the sulfonic acid groups of Sirius red 4B (acid form)." []
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0018033 CHEBI:88192 ! is deprotonated form of Sirius red 4B (acid form)

[Term]
id: CHEBI:88215
name: osmium tetroxide
def: "An osmium coordination entity consisting of four oxygen atoms bound to a central osmium atom via covalent double bonds." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35731 ! osmium coordination entity
relationship: RO:0000087 CHEBI:228364 ! has role NMR chemical shift reference compound
relationship: RO:0000087 CHEBI:50913 ! has role fixative
relationship: RO:0000087 CHEBI:63248 ! has role oxidising agent
relationship: RO:0000087 CHEBI:64909 ! has role poison
relationship: RO:0000087 CHEBI:77178 ! has role histological dye

[Term]
id: CHEBI:88227
name: potassium ionophore
def: "Any ionophore capable of transportation of potassium ions across membranes." []
is_a: CHEBI:24869 ! ionophore

[Term]
id: CHEBI:88230
name: autophagy inhibitor
def: "Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell)." []
is_a: CHEBI:35222 ! inhibitor
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:88249
name: PD 0325901
def: "A hydroxamic acid ester that is benzhydroxamic acid (<em>N</em>-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position 2 by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the <i>R</i> enantiomer)." []
is_a: CHEBI:26284 ! propane-1,2-diols
is_a: CHEBI:36586 ! carbonyl compound
is_a: CHEBI:37142 ! organoiodine compound
is_a: CHEBI:38582 ! difluorobenzene
is_a: CHEBI:50995 ! secondary amino compound
is_a: CHEBI:75606 ! hydroxamic acid ester
is_a: CHEBI:83575 ! monofluorobenzenes
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:88286 ! has role EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor

[Term]
id: CHEBI:88285
name: EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor
def: "An EC 2.7.* (<em>P</em>-containing group transferase) inhibitor that interferes with the action of duals specificity kinases acting on Ser/Thr and Tyr residues." []
is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor

[Term]
id: CHEBI:88286
name: EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
def: "An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of mitogen-activated protein kinase kinase (EC 2.7.12.2)." []
is_a: CHEBI:88285 ! EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor

[Term]
id: CHEBI:88306
name: 4-nitrophenols
def: "A mononitrophenol that is 4-nitrophenol and its derivatives resulting from substitution of one or more of the hydrogens attached to the benzene ring by a non-nitro group." []
is_a: CHEBI:39362 ! mononitrophenol

[Term]
id: CHEBI:88341
name: pyrrolotriazine
def: "Any organic heterobicyclic compound containing ortho-fused pyrrolidine and triazine rings." []
is_a: CHEBI:27171 ! organic heterobicyclic compound
is_a: CHEBI:38101 ! organonitrogen heterocyclic compound

[Term]
id: CHEBI:88432
name: 5-methyl-2-hexanone
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:8852
name: Ricin
is_a: CHEBI:50860 ! organic molecular entity

[Term]
id: CHEBI:88542
name: Butylparaben
is_a: CHEBI:79323 ! 4-hydroxybenzoate ester

[Term]
id: CHEBI:8866
name: rimsulfuron
def: "A  <em>N</em>-sulfonylurea that is <em>N</em>-carbamoyl-3-(ethylsulfonyl)pyridine-2-sulfonamide substituted by a 4,6-dimethoxypyrimidin-2-yl group at the amino nitrogen atom." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:35850 ! sulfone
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:8871
name: risperidone
def: "A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37143 ! organofluorine compound
is_a: CHEBI:38932 ! pyridopyrimidine
is_a: CHEBI:48585 ! heteroarylpiperidine
is_a: CHEBI:51545 ! 1,2-benzoxazoles
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0000087 CHEBI:37955 ! has role H1-receptor antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:65191 ! has role second generation antipsychotic
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor

[Term]
id: CHEBI:8884
name: rocuronium
def: "A 5α-androstane compound having 3α-hydroxy-, 17β-acetoxy-, 2β-morpholino- and 16β-<em>N</em>-allyllyrrolidinium substituents." []
is_a: CHEBI:35267 ! quaternary ammonium ion
is_a: CHEBI:35509 ! androstane
is_a: CHEBI:36835 ! 3alpha-hydroxy steroid
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:47622 ! acetate ester
is_a: CHEBI:47880 ! steroid ester
is_a: CHEBI:50996 ! tertiary amino compound
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:51371 ! has role muscle relaxant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0000087 CHEBI:90753 ! has role antidote to organophosphate poisoning
relationship: RO:0018040 CHEBI:28859 ! has parent hydride 5alpha-androstane

[Term]
id: CHEBI:88902
name: O-Desmethylangolensin
is_a: CHEBI:26776 ! stilbenoid

[Term]
id: CHEBI:89052
name: 2,5-dimethylfuran
def: "A member of the class of furans that is furan in which the hydrogens at positions 2 and 5 are replaced by methyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24129 ! furans
relationship: RO:0000087 CHEBI:33292 ! has role fuel
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:39276 ! has role fumigant
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite
relationship: RO:0000087 CHEBI:77523 ! has role Maillard reaction product
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite

[Term]
id: CHEBI:89195
name: 2-Methyl-4-heptanone
is_a: CHEBI:17087 ! ketone

[Term]
id: CHEBI:89484
name: 4-heptanone
def: "A dialkyl ketone that is heptane in which the two methylene protons at position 4 have been replaced by an oxo group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18044 ! dialkyl ketone
relationship: RO:0000087 CHEBI:59163 ! has role biomarker
relationship: RO:0000087 CHEBI:76967 ! has role human xenobiotic metabolite
relationship: RO:0000087 CHEBI:84087 ! has role human urinary metabolite
relationship: RO:0000087 CHEBI:86264 ! has role rat metabolite
relationship: RO:0018040 CHEBI:43098 ! has parent hydride heptane

[Term]
id: CHEBI:8984
name: sodium dodecyl sulfate
def: "An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26819 ! sulfuric ester
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:23872 ! has part dodecyl sulfate
relationship: RO:0000087 CHEBI:27780 ! has role detergent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:50533 ! has role protein denaturant

[Term]
id: CHEBI:8988
name: SN-38
def: "A member of the class of pyranoindolizinoquinolines that is (4<i>S</i>)-pyrano[3',4':6,7]indolizino[1,2-<em>b</em>]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:33853 ! phenols
is_a: CHEBI:48626 ! pyranoindolizinoquinoline
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:50276 ! has role EC 5.99.1.2 (DNA topoisomerase) inhibitor
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:8994
name: safrole
def: "A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38298 ! benzodioxoles
relationship: RO:0000087 CHEBI:24852 ! has role insecticide
relationship: RO:0000087 CHEBI:35617 ! has role flavouring agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:89993
name: 4-Methyl-3-penten-2-one, 9CI
is_a: CHEBI:78840 ! olefinic compound
relationship: RO:0018038 CHEBI:18308 ! has functional parent acrylic acid

[Term]
id: CHEBI:9009
name: Salidroside
is_a: CHEBI:24400 ! glycoside

[Term]
id: CHEBI:90318
name: EC 6.4.1.1 (pyruvate carboxylase) inhibitor
def: "An EC 6.4.1.* (carboxylase) inhibitor that interferes with the action of pyruvate carboxylase (EC 6.4.1.1)." []
is_a: CHEBI:76824 ! EC 6.4.1.* (carboxylase) inhibitor

[Term]
id: CHEBI:90396
name: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one
def: "An aromatic ketone that is phloroglucinol in which two of the hydrogens attached to the benzene ring have been replaced by chlorines while the third has been replaced by a hexanoyl group. It is the immediate biosynthetic precursor for differentiation-inducing factor 1 (DIF-1). DIF-1 is released by developing <em>Dictyostelium</em> amoebae, inducing them to differentiate into stalk cells." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22707 ! benzenetriol
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:75763 ! has role eukaryotic metabolite
relationship: RO:0018034 CHEBI:90398 ! is protonated form of (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one(1-)

[Term]
id: CHEBI:90397
name: 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one(1-)
def: "A phenolate anion resulting from the removal of a proton from one of the hydroxy groups of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one (DIF-1). The major structure at pH 7.3." []
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0018033 CHEBI:64598 ! is deprotonated form of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one

[Term]
id: CHEBI:90398
name: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one(1-)
def: "A phenolate anion resulting from removal of the proton from the phenolic hydroxy group of (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one that is <em>para</em> to the hexanoyl group. The major structure at pH 7.3." []
is_a: CHEBI:50525 ! phenolate anion
relationship: RO:0018033 CHEBI:90396 ! is deprotonated form of (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one

[Term]
id: CHEBI:90414
name: secretagogue
def: "A substance that causes another substance to be secreted." []
is_a: CHEBI:52206 ! biochemical role

[Term]
id: CHEBI:90415
name: insulin secretagogue
def: "A secretagogue that causes the secretion of insulin." []
is_a: CHEBI:90414 ! secretagogue

[Term]
id: CHEBI:9048
name: Schisantherin A
is_a: CHEBI:26848 ! tannin

[Term]
id: CHEBI:9062
name: scutellarein
def: "Flavone substituted with hydroxy groups at C-4', -5, -6 and -7." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38684 ! tetrahydroxyflavone
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0018034 CHEBI:78328 ! is protonated form of scutellarein(1-)
relationship: RO:0018038 CHEBI:18388 ! has functional parent apigenin

[Term]
id: CHEBI:90628
name: benzyl ester
def: "A carboxylic acid resulting from the formal condensation of the carboxy group of any carboxylic acid with the hydroxy group of benzyl alcohol." []
is_a: CHEBI:33308 ! carboxylic ester
relationship: RO:0018038 CHEBI:17987 ! has functional parent benzyl alcohol
relationship: RO:0018038 CHEBI:33575 ! has functional parent carboxylic acid

[Term]
id: CHEBI:90633
name: perfluorododecanoic acid
def: "A fluoroalkanoic acid that is dodecanoic acid in which all of the hydrogens attached to carbon atoms are replaced by fluorines. It is a highly persistent, bioaccumulative breakdown product of stain- and grease-proof coatings on food packaging, soft furnishings and carpets." []
is_a: CHEBI:35551 ! fluoroalkanoic acid
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:30805 ! has functional parent dodecanoic acid

[Term]
id: CHEBI:90675
name: ribonucleotide residue(1-)
def: "An organic anionic group obtained by deprotonation of the phosphate OH group of any ribonucleotide residue; major species at pH 7.3." []
is_a: CHEBI:64775 ! organic anionic group
relationship: RO:0018033 CHEBI:55366 ! is deprotonated form of ribonucleotide residue

[Term]
id: CHEBI:90688
name: metformin(1+)
def: "A guanidinium ion obtained by monoprotonation of metformin." []
is_a: CHEBI:60251 ! guanidinium ion
relationship: RO:0018034 CHEBI:6801 ! is protonated form of metformin

[Term]
id: CHEBI:90700
name: strychnine(1+)
def: "An indole alkaloid cation obtained by protonation of the tertiary amino group of strychnine." []
is_a: CHEBI:60521 ! indole alkaloid cation
relationship: RO:0018034 CHEBI:28973 ! is protonated form of strychnine

[Term]
id: CHEBI:90708
name: retinoic acid receptor modulator
def: "A nuclear receptor modulator that affects the retinoic acid receptor" []
is_a: CHEBI:90709 ! nuclear receptor modulator

[Term]
id: CHEBI:90709
name: nuclear receptor modulator
def: "Any receptor modulator acting on nuclear receptors" []
is_a: CHEBI:90710 ! receptor modulator

[Term]
id: CHEBI:90710
name: receptor modulator
def: "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." []
is_a: CHEBI:23888 ! drug

[Term]
id: CHEBI:90749
name: antidote to cyanide poisoning
def: "A role borne by a molecule that acts to counteract or neutralize the deleterious effects of cyanide." []
is_a: CHEBI:50247 ! antidote

[Term]
id: CHEBI:90753
name: antidote to organophosphate poisoning
def: "A role borne by a molecule that acts to counteract or neutralise the deleterious effects of organophosphates or acetylcholinesterase inhibitors (nerve agents)." []
is_a: CHEBI:50247 ! antidote

[Term]
id: CHEBI:90755
name: antidote to opioid poisoning
def: "A role borne by a molecule that acts to counteract or neutralise the deleterious effects of opioids." []
is_a: CHEBI:50247 ! antidote

[Term]
id: CHEBI:90799
name: dipeptide zwitterion
def: "Any peptide zwitterion comprising two amino acid residues. Major structure at pH 7.3." []
is_a: CHEBI:60466 ! peptide zwitterion
relationship: RO:0018036 CHEBI:46761 ! is tautomer of dipeptide

[Term]
id: CHEBI:90828
name: CHZ868
def: "A memger of the class of benzimidazoles that is benzimidazole that is substituted by methyl groups at positions 1 and 4, by a 2,4-difluoroanilino group at position 2, and by a (2-acetamidopyridin-4-yl)oxy group at position 5. It is a type II JAK2 inhibitor with antineoplastic activity." []
is_a: CHEBI:22160 ! acetamides
is_a: CHEBI:22715 ! benzimidazoles
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:33860 ! aromatic amine
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38582 ! difluorobenzene
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:76617 ! has role EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

[Term]
id: CHEBI:90852
name: N-sulfonylcarboxamide
def: "A mixed diacylamine resulting from the formal condensation of the nitrogen of a carboxamide with a sulphonic acid." []
is_a: CHEBI:37716 ! mixed diacylamine

[Term]
id: CHEBI:90895
name: irinotecan(1+)
def: "An organic cation obtained by protonation of the tertiary amino group of irinotecan." []
is_a: CHEBI:25697 ! organic cation
is_a: CHEBI:35274 ! ammonium ion derivative
relationship: RO:0018034 CHEBI:80630 ! is protonated form of irinotecan

[Term]
id: CHEBI:90929
name: lesinurad
def: "A member of the class of triazoles that is [(3-bromo-1,2,4-triazol-5-yl)sulfanyl]acetic acid substituted at position 1 of the triazole ring by a 4-cyclopropylnaphthalen-1-yl group. Used for treatment of gout." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:35683 ! aryl sulfide
is_a: CHEBI:35727 ! triazoles
is_a: CHEBI:37141 ! organobromine compound
is_a: CHEBI:51454 ! cyclopropanes
relationship: RO:0000087 CHEBI:35841 ! has role uricosuric drug

[Term]
id: CHEBI:9093
name: selenocysteine
def: "An α-amino acid that consists of alanine where one of the methyl hydrogens is substituted with a seleno group." []
is_a: CHEBI:33704 ! alpha-amino acid
relationship: BFO:0000051 CHEBI:50327 ! has part selanylmethyl group
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:32754 ! is deprotonated form of selenocysteinium
relationship: RO:0018034 CHEBI:32752 ! is protonated form of selenocysteinate(1-)

[Term]
id: CHEBI:91007
name: aromatic carboxylate
def: "A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3." []
is_a: CHEBI:29067 ! carboxylic acid anion
relationship: RO:0018033 CHEBI:33859 ! is deprotonated form of aromatic carboxylic acid

[Term]
id: CHEBI:91016
name: GABAA receptor agonist
def: "A GABA receptor agonist specific for GABA<small><sub>A</sub></small> receptors, ligand-gated ion channels (also known as ionotropic receptors)." []
is_a: CHEBI:51373 ! GABA agonist

[Term]
id: CHEBI:91025
name: erythropoietin inhibitor
def: "Any inhibitor of erythropoietin, a glycoprotein hormone that controls erythropoiesis (red blood cell production)." []
is_a: CHEBI:35222 ! inhibitor

[Term]
id: CHEBI:91079
name: purinergic receptor P2 antagonist
def: "An antagonist at purinergic P2 receptors" []
is_a: CHEBI:48706 ! antagonist

[Term]
id: CHEBI:91091
name: CHIR 99021
def: "A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively." []
is_a: CHEBI:23438 ! cyanopyridine
is_a: CHEBI:23666 ! diamine
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:24780 ! imidazoles
is_a: CHEBI:38207 ! aminopyridine
is_a: CHEBI:38338 ! aminopyrimidine
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:91092 ! has role EC 2.7.11.26 (tau-protein kinase) inhibitor

[Term]
id: CHEBI:91092
name: EC 2.7.11.26 (tau-protein kinase) inhibitor
def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of <em>tau</em>-protein kinase inhibitor (EC 2.7.11.26)." []
is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor

[Term]
id: CHEBI:91139
name: elastin-laminin receptor agonist
def: "An agonist that selectively binds to and activates elastin-laminin receptors." []
is_a: CHEBI:48705 ! agonist

[Term]
id: CHEBI:9123
name: sertraline
def: "A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the <i>S</i>,<i>S</i> diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder." []
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:36786 ! tetralins
is_a: CHEBI:50995 ! secondary amino compound
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0018033 CHEBI:64214 ! is deprotonated form of sertraline(1+)
relationship: RO:0018040 CHEBI:35008 ! has parent hydride tetralin

[Term]
id: CHEBI:9124
name: sertraline hydrochloride
def: "A hydrochloride resulting from the reaction of equimolar amounts of sertraline and hydrogen chloride. A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:36807 ! hydrochloride
relationship: BFO:0000051 CHEBI:64214 ! has part sertraline(1+)
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor

[Term]
id: CHEBI:91251
name: sodium glyoxylate
def: "An organic sodium salt that is the monosodium salt of glyoxylic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
relationship: BFO:0000051 CHEBI:36655 ! has part glyoxylate
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:75772 ! has role Saccharomyces cerevisiae metabolite
relationship: RO:0000087 CHEBI:76971 ! has role Escherichia coli metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite

[Term]
id: CHEBI:9130
name: sevoflurane
def: "An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25698 ! ether
is_a: CHEBI:37143 ! organofluorine compound
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:38870 ! has role inhalation anaesthetic
relationship: RO:0000087 CHEBI:50247 ! has role antidote
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0018038 CHEBI:53505 ! has functional parent 2-methoxypropane

[Term]
id: CHEBI:9139
name: sildenafil
def: "A pyrazolo[4,3-<em>d</em>]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26144 ! piperazines
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:38669 ! pyrazolopyrimidine
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:39456 ! has role antiglaucoma drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:49201 ! has role anti-ulcer drug
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:71942 ! has role EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent

[Term]
id: CHEBI:9144
name: silibinin
def: "A flavonolignan isolated from milk thistle, <em>Silybum marianum</em>, that has been shown to exhibit antioxidant and antineoplastic activities." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:2468 ! secondary alpha-hydroxy ketone
is_a: CHEBI:26195 ! polyphenol
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:64096 ! benzodioxine
is_a: CHEBI:72709 ! flavonolignan
relationship: RO:0000087 CHEBI:22586 ! has role antioxidant
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:9150
name: simvastatin
def: "A member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug." []
is_a: CHEBI:142348 ! hexahydronaphthalenes
is_a: CHEBI:18946 ! delta-lactone
is_a: CHEBI:35748 ! fatty acid ester
is_a: CHEBI:87633 ! statin (semi-synthetic)
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:50266 ! has role prodrug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:65023 ! has role anti-asthmatic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75835 ! has role anti-anaemic agent
relationship: RO:0000087 CHEBI:77255 ! has role EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
relationship: RO:0018038 CHEBI:40303 ! has functional parent lovastatin

[Term]
id: CHEBI:91519
name: norketamine
def: "A member of the class of cyclohexanones that is cyclohexanone in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by an amino group. It is the major metabolite of ketamine." []
is_a: CHEBI:23482 ! cyclohexanones
is_a: CHEBI:50994 ! primary amino compound
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:228138 ! has role antinociceptive agent
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:48878 ! has role nicotinic antagonist
relationship: RO:0000087 CHEBI:49103 ! has role drug metabolite
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist

[Term]
id: CHEBI:9168
name: sirolimus
def: "A macrolide lactam isolated from <em>Streptomyces hygroscopicus</em> consisting of a 29-membered ring containing 4 <i>trans</i> double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent." []
is_a: CHEBI:145565 ! macrolide lactam
is_a: CHEBI:25698 ! ether
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:59770 ! cyclic acetal
is_a: CHEBI:87113 ! antibiotic antifungal drug
relationship: RO:0000087 CHEBI:149553 ! has role anticoronaviral agent
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:68481 ! has role mTOR inhibitor
relationship: RO:0000087 CHEBI:76969 ! has role bacterial metabolite

[Term]
id: CHEBI:9195
name: Soman
is_a: CHEBI:37735 ! phosphonic ester

[Term]
id: CHEBI:920
name: 2,4-dinitrotoluene
def: "A dinitrotoluene in which the methyl group is <em>ortho</em> to one of the nitro groups and <em>para</em> to the other. It is the most common isomer of dinitrotoluene." []
is_a: CHEBI:23822 ! dinitrotoluene

[Term]
id: CHEBI:9209
name: soyasapogenol B
def: "A pentacyclic triterpenoid that is oleanane containing a double bond between positions 12 and 13 and substituted by hydroxy groups at the 3β, 22β and 24-positions." []
is_a: CHEBI:25872 ! pentacyclic triterpenoid
relationship: RO:0018040 CHEBI:36481 ! has parent hydride oleanane

[Term]
id: CHEBI:92184
name: GW405833
def: "A methylindole that is 2-methyl-1<em>H</em>-indole substituted by 2,3-dichlorobenzoyl, 2-(morpholin-4-yl)ethyl, and methoxy groups at positions 1, 3 and 5, respectively. It is a partial agonist of the cannabinoid CB<small><sub>2</sub></small> receptor (EC<small><sub>50</sub></small> = 0.65 nM)." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22702 ! benzamides
is_a: CHEBI:23697 ! dichlorobenzene
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:38460 ! methylindole
is_a: CHEBI:38785 ! morpholines
is_a: CHEBI:75884 ! N-acylindole
relationship: RO:0000087 CHEBI:146246 ! has role CB2 receptor agonist
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent

[Term]
id: CHEBI:9241
name: spironolactone
def: "A  steroid lactone that is 17α-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an α-acetylsulfanyl group at position 7." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26766 ! steroid lactone
is_a: CHEBI:37948 ! oxaspiro compound
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:51277 ! thioester
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35498 ! has role diuretic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:50844 ! has role aldosterone antagonist
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:9242
name: spiroxamine
def: "The spiroketal resulting from the formal condensation of 4-<em>tert</em>-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powdery mildew in the production of cereals, bananas and grapes." []
is_a: CHEBI:39430 ! dioxolane
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:72600 ! spiroketal
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:83317 ! has role sterol biosynthesis inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:9288
name: streptozocin
def: "An <em>N</em>-nitrosourea that is an antibiotic produced by <em>Streptomyces achromogenes</em>. It is used as an antineoplastic agent and to induce diabetes in experimental animals." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:21638 ! N-acylglucosamine
is_a: CHEBI:76551 ! N-nitrosoureas
relationship: RO:0000087 CHEBI:25212 ! has role metabolite
relationship: RO:0000087 CHEBI:33281 ! has role antimicrobial agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:59517 ! has role DNA synthesis inhibitor

[Term]
id: CHEBI:9300
name: suberic acid
def: "An α,ω-dicarboxylic acid that is the 1,6-dicarboxy derivative of hexane." []
is_a: CHEBI:189840 ! dicarboxylic fatty acid
is_a: CHEBI:28383 ! alpha,omega-dicarboxylic acid
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:76282 ! is protonated form of suberate(2-)

[Term]
id: CHEBI:9328
name: sulfadiazine
def: "A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position." []
is_a: CHEBI:39447 ! pyrimidines
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:87228 ! sulfonamide antibiotic
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35818 ! has role coccidiostat
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50502 ! has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor
relationship: RO:0000087 CHEBI:74234 ! has role EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018034 CHEBI:33127 ! is protonated form of sulfadiazinate
relationship: RO:0018038 CHEBI:45373 ! has functional parent sulfanilamide

[Term]
id: CHEBI:9330
name: sulfamic acid
def: "The simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to hydroxy and amino groups and by double bonds to two oxygen atoms." []
is_a: CHEBI:35719 ! sulfamic acids

[Term]
id: CHEBI:9332
name: sulfamethoxazole
def: "An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position." []
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:55373 ! isoxazoles
is_a: CHEBI:87228 ! sulfonamide antibiotic
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:33231 ! has role antitubercular agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:38068 ! has role antimalarial
relationship: RO:0000087 CHEBI:50177 ! has role dermatologic drug
relationship: RO:0000087 CHEBI:50183 ! has role P450 inhibitor
relationship: RO:0000087 CHEBI:50502 ! has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor
relationship: RO:0000087 CHEBI:53000 ! has role epitope
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:74234 ! has role EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:45373 ! has functional parent sulfanilamide

[Term]
id: CHEBI:9334
name: sulfasalazine
def: "An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:22682 ! azobenzenes
is_a: CHEBI:26421 ! pyridines
is_a: CHEBI:35358 ! sulfonamide
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35475 ! has role non-steroidal anti-inflammatory drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:50919 ! has role antiemetic
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug
relationship: RO:0000087 CHEBI:76797 ! has role EC 2.5.1.18 (glutathione transferase) inhibitor
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:45373 ! has functional parent sulfanilamide

[Term]
id: CHEBI:9337
name: sulfathiazole
def: "A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position." []
is_a: CHEBI:38418 ! 1,3-thiazoles
is_a: CHEBI:48975 ! substituted aniline
is_a: CHEBI:87228 ! sulfonamide antibiotic
relationship: RO:0000087 CHEBI:33282 ! has role antibacterial agent
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50502 ! has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0000087 CHEBI:88188 ! has role drug allergen
relationship: RO:0018038 CHEBI:45373 ! has functional parent sulfanilamide

[Term]
id: CHEBI:9341
name: sulfinate
is_a: CHEBI:33482 ! sulfur oxoanion
relationship: RO:0018033 CHEBI:29213 ! is deprotonated form of sulfinic acid

[Term]
id: CHEBI:9398
name: tamsulosin
def: "A 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide that has (<i>R</i>)-configuration. A specific α<small><sub>1</sub></small> adrenoceptor antagonist used (generally as its hydrochloride salt, tamsulosin hydrochloride) in the treatment of prostatic hyperplasia, chronic prostatitis, urinary retention, and help with the passage of kidney stones." []
is_a: CHEBI:142546 ! 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide
is_a: CHEBI:35338 ! amphetamines
relationship: RO:0000087 CHEBI:35441 ! has role antiinfective agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0018033 CHEBI:142544 ! is deprotonated form of tamsulosin(1+)
relationship: RO:0018039 CHEBI:142548 ! is enantiomer of ent-tamsulosin

[Term]
id: CHEBI:9407
name: taurochenodeoxycholate
def: "An organosulfonate oxoanion that is the conjugate base of taurochenodeoxycholic acid arising from deprotonation of the sulfonate OH group; major species at pH 7.3." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:131879 ! cholanic acid conjugate anion
is_a: CHEBI:33554 ! organosulfonate oxoanion
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018033 CHEBI:16525 ! is deprotonated form of taurochenodeoxycholic acid

[Term]
id: CHEBI:9422
name: tebufenpyrad
is_a: CHEBI:26409 ! pyrazole insecticide
is_a: CHEBI:38602 ! pyrazole acaricide
relationship: RO:0000087 CHEBI:38498 ! has role mitochondrial NADH:ubiquinone reductase inhibitor

[Term]
id: CHEBI:94288
name: L-buthionine-(S,R)-sulfoximine
def: "A 2-amino-4-(<em>S</em>-butylsulfonimidoyl)butanoic acid which has <i>S</i>-configuration. It is a inhibitor of γ-glutamylcysteine synthetase and glutathione (GSH) biosynthesis and is capable of enhancing the apoptotic effects of several chemotherapeutic agents." []
is_a: CHEBI:176510 ! 2-amino-4-(S-butylsulfonimidoyl)butanoic acid
relationship: RO:0000087 CHEBI:173085 ! has role ferroptosis inducer
relationship: RO:0000087 CHEBI:75599 ! has role EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor

[Term]
id: CHEBI:943
name: 2,6-dichlorobenzonitrile
def: "A nitrile that is benzonitrile which is substituted by chlorines at positions 2 and 6. A cellulose synthesis inhibitor, it is used as a pre-emergent and early post-emergent herbicide." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:23697 ! dichlorobenzene
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:63958 ! has role cellulose synthesis inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:27991 ! has functional parent benzonitrile

[Term]
id: CHEBI:94301
name: YK-4-279
def: "A member of the class of indolones that is 1,3-dihydro-2<em>H</em>-indol-2-one substituted by hydroxy, 2-(4-methoxyphenyl)-2-oxoethyl, chloro, and chloro groups at positions 3, 3, 4, and 7, respectively. It blocks RNA helicase A binding to EWS-FLI1, induces apoptosis, and exhibits antineoplastic activity." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:24829 ! indolones
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:76224 ! aromatic ketone
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:68495 ! has role apoptosis inducer

[Term]
id: CHEBI:9434
name: telmisartan
def: "A member of the class of  benzimidazoles  used widely in the treatment of hypertension." []
is_a: CHEBI:141493 ! carboxybiphenyl
is_a: CHEBI:22715 ! benzimidazoles
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35457 ! has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:61016 ! has role angiotensin receptor antagonist
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:94373
name: mosapride
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT<small><sub>4</sub></small>) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:167205 ! has part (R)-mosapride
relationship: BFO:0000051 CHEBI:167206 ! has part (S)-mosapride
relationship: RO:0000087 CHEBI:35941 ! has role serotonergic agonist
relationship: RO:0000087 CHEBI:50503 ! has role laxative
relationship: RO:0000087 CHEBI:53784 ! has role antispasmodic drug
relationship: RO:0000087 CHEBI:55324 ! has role gastrointestinal drug

[Term]
id: CHEBI:9447
name: Terbacil
is_a: CHEBI:17792 ! organohalogen compound
is_a: CHEBI:39447 ! pyrimidines

[Term]
id: CHEBI:94471
name: (R,R)-labetalol
def: "A 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1<i>R</i>,2<i>R</i>-configuration." []
is_a: CHEBI:167638 ! 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide
relationship: RO:0018033 CHEBI:191214 ! is deprotonated form of dilevalol(1+)

[Term]
id: CHEBI:9448
name: terbinafine
def: "A tertiary amine that is <em>N</em>-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(<em>tert</em>butylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections." []
is_a: CHEBI:25477 ! naphthalenes
is_a: CHEBI:32876 ! tertiary amine
is_a: CHEBI:59831 ! enyne
is_a: CHEBI:87127 ! allylamine antifungal drug
relationship: RO:0000087 CHEBI:50183 ! has role P450 inhibitor
relationship: RO:0000087 CHEBI:59285 ! has role EC 1.14.13.132 (squalene monooxygenase) inhibitor
relationship: RO:0000087 CHEBI:64951 ! has role anti-HBV agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:83317 ! has role sterol biosynthesis inhibitor
relationship: RO:0018033 CHEBI:77615 ! is deprotonated form of terbinafine(1+)

[Term]
id: CHEBI:94633
name: 2-(tetradecylthio)acetic acid
is_a: CHEBI:59202 ! straight-chain fatty acid

[Term]
id: CHEBI:94646
name: N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester
is_a: CHEBI:38207 ! aminopyridine
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent

[Term]
id: CHEBI:94770
name: pirarubicin
def: "An anthracycline that is doxorubicin in which the hydroxy group at position 4' is replaced by a (2<i>R</i>)-tetrahydro-2<em>H</em>-pyran-2-yloxy group." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:25830 ! p-quinones
is_a: CHEBI:35315 ! deoxy hexoside
is_a: CHEBI:46942 ! oxanes
is_a: CHEBI:47779 ! aminoglycoside
is_a: CHEBI:48120 ! anthracycline
is_a: CHEBI:51286 ! tetracenequinones
is_a: CHEBI:63367 ! monosaccharide derivative
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50912 ! has role cardiotoxic agent
relationship: RO:0018038 CHEBI:28748 ! has functional parent doxorubicin

[Term]
id: CHEBI:9495
name: thiram
def: "An organic disulfide that results from the formal oxidative dimerisation of <em>N</em>,<em>N</em>-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:35489 ! organic disulfide
relationship: BFO:0000051 CHEBI:84293 ! has part dimethyldithiocarbamate
relationship: RO:0000087 CHEBI:35442 ! has role antiparasitic agent
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug
relationship: RO:0000087 CHEBI:48218 ! has role antiseptic drug
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical
relationship: RO:0018038 CHEBI:83061 ! has functional parent dimethyldithiocarbamic acid

[Term]
id: CHEBI:95028
name: sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7-pyrrolo[2,3-d]pyrimidinyl]-2-hydroxycyclopentyl]methyl ester
is_a: CHEBI:46940 ! indanes

[Term]
id: CHEBI:9516
name: thapsigargin
def: "An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of <em>Thapsia garganica</em> L., <em>Apiaceae</em>. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits <em>Ca</em><small><sup>2+</small></sup>-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26979 ! organic heterotricyclic compound
is_a: CHEBI:37667 ! sesquiterpene lactone
is_a: CHEBI:50477 ! butyrate ester
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:60186 ! has role EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor

[Term]
id: CHEBI:95341
name: baricitinib
def: "A pyrrolopyrimidine that is 7<em>H</em>-pyrrolo[2,3-<em>d</em>]pyrimidine substituted by a 1-[3-(cyanomethyl)-1-(ethanesulfonyl)azetidin-3-yl]-1<em>H</em>-pyrazol-4-yl group at position 5. It is an FDA approved selective Janus Kinase 1 and 2 (JAK1 and JAK2) inhibitor used for the treatment of rheumatoid arthritis." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:18379 ! nitrile
is_a: CHEBI:26410 ! pyrazoles
is_a: CHEBI:35358 ! sulfonamide
is_a: CHEBI:38670 ! pyrrolopyrimidine
is_a: CHEBI:38777 ! azetidines
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35705 ! has role immunosuppressive agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:63726 ! has role neuroprotective agent
relationship: RO:0000087 CHEBI:64946 ! has role anti-HIV agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:76617 ! has role EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

[Term]
id: CHEBI:9553
name: thioglucoside
def: "An <em>S</em>-glycosyl in which the anomeric hydroxyl group of a glucose has been replaced by a sulfide (-SR) group." []
is_a: CHEBI:35275 ! S-glycosyl compound
relationship: RO:0018038 CHEBI:17234 ! has functional parent glucose

[Term]
id: CHEBI:9566
name: thioridazine
def: "A phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26151 ! piperidines
is_a: CHEBI:38093 ! phenothiazines
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:48563 ! has part methylsulfanyl group
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:37890 ! has role alpha-adrenergic antagonist
relationship: RO:0000087 CHEBI:37955 ! has role H1-receptor antagonist
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48561 ! has role dopaminergic antagonist
relationship: RO:0000087 CHEBI:65190 ! has role first generation antipsychotic
relationship: RO:0000087 CHEBI:76779 ! has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0000087 CHEBI:77402 ! has role EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor

[Term]
id: CHEBI:957
name: 2,6-dinitrotoluene
def: "A dinitrotoluene carrying nitro substituents at positions 2 and 6." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23822 ! dinitrotoluene
relationship: RO:0000087 CHEBI:50902 ! has role genotoxin

[Term]
id: CHEBI:9588
name: ticlopidine
def: "A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-<em>c</em>]pyridine in which the hydrogen attached to the nitrogen is replaced by an <em>o</em>-chlorobenzyl group." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:37942 ! thienopyridine
is_a: CHEBI:83403 ! monochlorobenzenes
relationship: RO:0000087 CHEBI:48676 ! has role fibrin modulating drug
relationship: RO:0000087 CHEBI:50249 ! has role anticoagulant
relationship: RO:0000087 CHEBI:50427 ! has role platelet aggregation inhibitor
relationship: RO:0000087 CHEBI:68563 ! has role P2Y12 receptor antagonist

[Term]
id: CHEBI:9648
name: tramadol
def: "A racemate consisting of equal amounts of (<i>R</i>,<i>R</i>)- and (<i>S</i>,<i>S</i>)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (<i>R</i>,<i>R</i>)-enantiomer exhibits ten-fold higher analgesic potency than the (<i>S</i>,<i>S</i>)-enantiomer. Originally developed by Grünenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree <em>Nauclea latifolia</em>." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:75725 ! has part (R,R)-tramadol
relationship: BFO:0000051 CHEBI:75731 ! has part (S,S)-tramadol
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35482 ! has role opioid analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:48279 ! has role serotonergic antagonist
relationship: RO:0000087 CHEBI:48876 ! has role muscarinic antagonist
relationship: RO:0000087 CHEBI:48878 ! has role nicotinic antagonist
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:51177 ! has role antitussive
relationship: RO:0000087 CHEBI:55322 ! has role mu-opioid receptor agonist
relationship: RO:0000087 CHEBI:59282 ! has role kappa-opioid receptor agonist
relationship: RO:0000087 CHEBI:60643 ! has role NMDA receptor antagonist
relationship: RO:0000087 CHEBI:64054 ! has role delta-opioid receptor agonist
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:70774 ! has role capsaicin receptor antagonist
relationship: RO:0000087 CHEBI:73336 ! has role vulnerary
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018033 CHEBI:75736 ! is deprotonated form of tramadol(1+)

[Term]
id: CHEBI:9665
name: triadimefon
def: "A racemate comprising equal amounts of (<i>R</i>)- and (<i>S</i>)-triadimefon. A fungicide used to control powdery mildew, rusts and other infections in crops." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87067 ! conazole fungicide
is_a: CHEBI:87100 ! triazole fungicide
relationship: BFO:0000051 CHEBI:84003 ! has part (R)-triadimefon
relationship: BFO:0000051 CHEBI:84004 ! has part (S)-triadimefon
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:9667
name: triamcinolone
def: "A C<small><sub>21</sub></small>-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11β, 16α, 17α and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections." []
is_a: CHEBI:139590 ! primary alpha-hydroxy ketone
is_a: CHEBI:139592 ! tertiary alpha-hydroxy ketone
is_a: CHEBI:16799 ! 16alpha-hydroxy steroid
is_a: CHEBI:24261 ! glucocorticoid
is_a: CHEBI:35342 ! 17alpha-hydroxy steroid
is_a: CHEBI:35344 ! 21-hydroxy steroid
is_a: CHEBI:35346 ! 11beta-hydroxy steroid
is_a: CHEBI:36885 ! 20-oxo steroid
is_a: CHEBI:47909 ! 3-oxo-Delta(4) steroid
is_a: CHEBI:50830 ! fluorinated steroid
is_a: CHEBI:64600 ! C21-steroid hormone
relationship: RO:0000087 CHEBI:35472 ! has role anti-inflammatory drug
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:50748 ! has role antipsoriatic
relationship: RO:0000087 CHEBI:50857 ! has role anti-allergic agent
relationship: RO:0000087 CHEBI:66981 ! has role ophthalmology drug
relationship: RO:0000087 CHEBI:77715 ! has role nasal decongestant
relationship: RO:0018040 CHEBI:8386 ! has parent hydride pregnane

[Term]
id: CHEBI:9678
name: tribenuron methyl
def: "The methyl ester of tribenuron." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:25248 ! methyl ester
is_a: CHEBI:36054 ! benzoate ester
is_a: CHEBI:38177 ! methoxy-1,3,5-triazine
is_a: CHEBI:76983 ! N-sulfonylurea
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0018038 CHEBI:83571 ! has functional parent tribenuron

[Term]
id: CHEBI:9682
name: trichlopyr
def: "A monocarboxylic acid that is (pyridin-2-yloxy)acetic acid substituted by chloro groups at positions 3, 5 and 6. It is an agrochemical used as a herbicide." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:35618 ! aromatic ether
is_a: CHEBI:39173 ! chloropyridine
relationship: RO:0000087 CHEBI:24527 ! has role herbicide
relationship: RO:0000087 CHEBI:33286 ! has role agrochemical
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:9688
name: trichodermin
def: "A tetracyclic spiroepoxide which acts as an antifungal and protein synthesis inhibitor." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:32955 ! epoxide
is_a: CHEBI:38163 ! organic heterotetracyclic compound
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35718 ! has role antifungal agent
relationship: RO:0000087 CHEBI:48001 ! has role protein synthesis inhibitor

[Term]
id: CHEBI:9715
name: triforine
def: "A member of the class of <em>N</em>-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust." []
is_a: CHEBI:24079 ! formamides
is_a: CHEBI:36683 ! organochlorine compound
is_a: CHEBI:46845 ! N-alkylpiperazine
is_a: CHEBI:60600 ! amide fungicide
relationship: RO:0000087 CHEBI:50904 ! has role allergen
relationship: RO:0000087 CHEBI:77884 ! has role EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:9728
name: trimethaphan
def: "A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:26830 ! sulfonium compound
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:48878 ! has role nicotinic antagonist
relationship: RO:0000087 CHEBI:50864 ! has role insulin-sensitizing drug
relationship: RO:0000087 CHEBI:60807 ! has role anaesthesia adjuvant

[Term]
id: CHEBI:9729
name: trimethaphan camsylate
def: "The (<i>S</i>)-camphorsulfonate salt of trimethaphan." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:55339 ! camphorsulfonate salt
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:55408 ! has part (S)-camphorsulfonate
relationship: BFO:0000051 CHEBI:9728 ! has part trimethaphan
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent

[Term]
id: CHEBI:9738
name: trimipramine
def: "A dibenzoazepine that is 10,11-dihydro-5<em>H</em>-dibenzo[<em>b,f</em>]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant." []
is_a: CHEBI:47804 ! dibenzoazepine
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35474 ! has role anxiolytic drug
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant
relationship: RO:0018038 CHEBI:47499 ! has functional parent imipramine

[Term]
id: CHEBI:9747
name: Triptolide
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:23849 ! diterpenoid
is_a: CHEBI:32955 ! epoxide
is_a: CHEBI:52157 ! organic heteroheptacyclic compound
is_a: CHEBI:74222 ! gamma-lactam
relationship: RO:0000087 CHEBI:145047 ! has role antispermatogenic agent
relationship: RO:0000087 CHEBI:76924 ! has role plant metabolite

[Term]
id: CHEBI:9750
name: Triton X-100
def: "A poly(ethylene glycol) derivative that is poly(ethylene glycol) in which one of the terminal hydroxy groups has been converted into the corresponding <em>p</em>-(2,4,4-trimethylpentan-3-yl)phenyl ether." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:139322 ! poly(ethylene glycol) derivative
relationship: RO:0000087 CHEBI:38828 ! has role nonionic surfactant

[Term]
id: CHEBI:9907
name: ursodeoxycholic acid
def: "A bile acid found in the bile of bears (Ursidae) as a conjugate with taurine. Used therapeutically, it prevents the synthesis and absorption of cholesterol and can lead to the dissolution of gallstones." []
is_a: CHEBI:131620 ! C24-steroid
is_a: CHEBI:23775 ! dihydroxy-5beta-cholanic acid
is_a: CHEBI:3098 ! bile acid
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:233423 ! has role antifibrotic agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35554 ! has role cardiovascular drug
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35842 ! has role antirheumatic drug
relationship: RO:0000087 CHEBI:48407 ! has role antiparkinson drug
relationship: RO:0000087 CHEBI:62868 ! has role hepatoprotective agent
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:74518 ! has role anti-obesity agent
relationship: RO:0000087 CHEBI:75771 ! has role mouse metabolite
relationship: RO:0000087 CHEBI:77746 ! has role human metabolite
relationship: RO:0018034 CHEBI:78604 ! is protonated form of ursodeoxycholate

[Term]
id: CHEBI:9925
name: sodium valproate
def: "The sodium salt of valproic acid." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:38700 ! organic sodium salt
is_a: CHEBI:61697 ! fatty acid derivative
relationship: BFO:0000051 CHEBI:60654 ! has part valproate
relationship: RO:0000087 CHEBI:176497 ! has role geroprotector
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35623 ! has role anticonvulsant
relationship: RO:0000087 CHEBI:61115 ! has role EC 3.5.1.98 (histone deacetylase) inhibitor

[Term]
id: CHEBI:9927
name: valsartan
def: "A monocarboxylic acid amide consisting of <small>L</small>-valine in which the amino hydrogens have been replaced by a pentanoyl and a  [2'-(1<em>H</em>-tetrazol-5-yl)biphenyl]-4-yl]methyl group. It exhibits  antihypertensive activity." []
is_a: CHEBI:25384 ! monocarboxylic acid
is_a: CHEBI:29347 ! monocarboxylic acid amide
is_a: CHEBI:48420 ! biphenylyltetrazole
is_a: CHEBI:51569 ! N-acyl-amino acid
relationship: RO:0000087 CHEBI:145947 ! has role antiatherosclerotic agent
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:231911 ! has role renoprotective agent
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:61016 ! has role angiotensin receptor antagonist
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:9937
name: vasopressin
def: "A family of cyclic nonapeptide hormones found in most mammals. Synthesised in the hypothalamus and stored in the post-pituitary, vasopressins play a key rôle in homeostasis, particularly in regulating the body's water content. Together with the similar neuropeptide oxytocin, they are believed to influence social cognition and behaviour." []
is_a: CHEBI:24533 ! heterodetic cyclic peptide
is_a: CHEBI:25905 ! peptide hormone

[Term]
id: CHEBI:9943
name: venlafaxine
def: "A tertiary amino compound that is <em>N</em>,<em>N</em>-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group." []
is_a: CHEBI:23480 ! cyclohexanols
is_a: CHEBI:25235 ! monomethoxybenzene
is_a: CHEBI:26878 ! tertiary alcohol
is_a: CHEBI:50996 ! tertiary amino compound
is_a: CHEBI:60911 ! racemate
relationship: RO:0000087 CHEBI:35469 ! has role antidepressant
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35640 ! has role adrenergic uptake inhibitor
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:50949 ! has role serotonin uptake inhibitor
relationship: RO:0000087 CHEBI:51039 ! has role dopamine uptake inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:9948
name: verapamil
def: "A racemate comprising equimolar amounts of dexverapamil and (<i>S</i>)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine." []
is_a: BFO:0000004 ! independent continuant
is_a: CHEBI:50860 ! organic molecular entity
is_a: CHEBI:60911 ! racemate
relationship: BFO:0000051 CHEBI:77734 ! has part dexverapamil
relationship: BFO:0000051 CHEBI:77736 ! has part (S)-verapamil
relationship: RO:0000087 CHEBI:22587 ! has role antiviral agent
relationship: RO:0000087 CHEBI:35476 ! has role antipsychotic agent
relationship: RO:0000087 CHEBI:35480 ! has role analgesic
relationship: RO:0000087 CHEBI:35526 ! has role hypoglycemic agent
relationship: RO:0000087 CHEBI:35610 ! has role antineoplastic agent
relationship: RO:0000087 CHEBI:35620 ! has role vasodilator agent
relationship: RO:0000087 CHEBI:35674 ! has role antihypertensive agent
relationship: RO:0000087 CHEBI:35703 ! has role xenobiotic
relationship: RO:0000087 CHEBI:38070 ! has role anti-arrhythmia drug
relationship: RO:0000087 CHEBI:38215 ! has role calcium channel blocker
relationship: RO:0000087 CHEBI:62872 ! has role EC 1.2.3.1 (aldehyde oxidase) inhibitor
relationship: RO:0000087 CHEBI:67079 ! has role anti-inflammatory agent
relationship: RO:0000087 CHEBI:77255 ! has role EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
relationship: RO:0000087 CHEBI:77745 ! has role EC 3.4.24.18 (meprin A) inhibitor
relationship: RO:0000087 CHEBI:77747 ! has role EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor
relationship: RO:0000087 CHEBI:77748 ! has role EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: CHEBI:9986
name: vinclozolin
def: "A racemate comprising equimolar amounts of (<i>R</i>)- and (<i>S</i>)-vinclozolin.  A fungicide used mainly on oilseed rape, vines, fruit and vegetables to control <em>Botrytis</em>, <em>Sclerotinia</em> and <em>Monilia</em> spp." []
is_a: CHEBI:60911 ! racemate
is_a: CHEBI:87197 ! dichlorophenyl dicarboximide fungicide
relationship: BFO:0000051 CHEBI:83733 ! has part (R)-vinclozolin
relationship: BFO:0000051 CHEBI:83735 ! has part (S)-vinclozolin
relationship: RO:0000087 CHEBI:35497 ! has role androgen antagonist
relationship: RO:0000087 CHEBI:86328 ! has role antifungal agrochemical

[Term]
id: CHEBI:9997
name: pristinamycin IIA
def: "A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by <em>Streptomyces pristinaespiralis</em>. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant <em>Staphylococcus aureus</em>." []
is_a: CHEBI:140325 ! secondary carboxamide
is_a: CHEBI:140326 ! tertiary carboxamide
is_a: CHEBI:23763 ! pyrroline
is_a: CHEBI:24995 ! lactam
is_a: CHEBI:25105 ! macrolide antibiotic
is_a: CHEBI:35681 ! secondary alcohol
is_a: CHEBI:3992 ! cyclic ketone
is_a: CHEBI:46812 ! 1,3-oxazoles
is_a: CHEBI:51751 ! enamide
relationship: RO:0000087 CHEBI:131604 ! has role Mycoplasma genitalium metabolite
relationship: RO:0000087 CHEBI:36047 ! has role antibacterial drug

[Term]
id: ECTO:0000001
name: exposure to radiation
def: "A exposure event involving the interaction of an exposure receptor to radiation." []
synonym: "radiation exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001023 ! has exposure stimulus radiation
relationship: RO:0002309 ENVO:01001023 ! has exposure stimulus radiation

[Term]
id: ECTO:0000002
name: exposure to electromagnetic radiation
def: "A exposure event involving the interaction of an exposure receptor to electromagnetic radiation." []
synonym: "electromagnetic radiation exposure" EXACT []
is_a: ECTO:0000001 ! exposure to radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001026 ! has exposure stimulus electromagnetic radiation
relationship: RO:0002309 ENVO:01001026 ! has exposure stimulus electromagnetic radiation

[Term]
id: ECTO:0000006
name: exposure to ultraviolet radiation
def: "A exposure event involving the interaction of an exposure receptor to ultraviolet radiation." []
synonym: "ultraviolet radiation exposure" EXACT []
is_a: ECTO:0000002 ! exposure to electromagnetic radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001216 ! has exposure stimulus ultraviolet radiation
relationship: RO:0002309 ENVO:21001216 ! has exposure stimulus ultraviolet radiation

[Term]
id: ECTO:0000007
name: exposure to visible light radiation
def: "A exposure event involving the interaction of an exposure receptor to visible spectrum radiation." []
synonym: "visible spectrum radiation exposure" EXACT []
is_a: ECTO:0000002 ! exposure to electromagnetic radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001215 ! has exposure stimulus visible spectrum radiation
relationship: RO:0002309 ENVO:21001215 ! has exposure stimulus visible spectrum radiation

[Term]
id: ECTO:0000015
name: exposure to environmental material
def: "A exposure event involving the interaction of an exposure receptor to environmental material." []
synonym: "environmental material exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00010483 ! has exposure stimulus environmental material
relationship: RO:0002309 ENVO:00010483 ! has exposure stimulus environmental material

[Term]
id: ECTO:0000135
name: exposure to organic compound
def: "An exposure to organic molecular entity." []
synonym: "organic molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50860 ! has exposure stimulus organic molecular entity
relationship: RO:0002309 CHEBI:50860 ! has exposure stimulus organic molecular entity

[Term]
id: ECTO:0000163
name: exposure to organic cyclic compound
def: "An exposure to organic cyclic compound." []
synonym: "organic cyclic compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33832 ! has exposure stimulus organic cyclic compound
relationship: RO:0002309 CHEBI:33832 ! has exposure stimulus organic cyclic compound

[Term]
id: ECTO:0000172
name: exposure to methotrexate
def: "An exposure to methotrexate." []
synonym: "methotrexate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44185 ! has exposure stimulus methotrexate
relationship: RO:0002309 CHEBI:44185 ! has exposure stimulus methotrexate

[Term]
id: ECTO:0000173
name: exposure to corticosteroid
def: "An exposure to corticosteroid." []
synonym: "corticosteroid exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50858 ! has exposure stimulus corticosteroid
relationship: RO:0002309 CHEBI:50858 ! has exposure stimulus corticosteroid

[Term]
id: ECTO:0000200
name: exposure to lipid
def: "An exposure to lipid." []
synonym: "lipid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18059 ! has exposure stimulus lipid
relationship: RO:0002309 CHEBI:18059 ! has exposure stimulus lipid

[Term]
id: ECTO:0000207
name: exposure to carbon monoxide
def: "An exposure to carbon monoxide." []
synonym: "carbon monoxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17245 ! has exposure stimulus carbon monoxide
relationship: RO:0002309 CHEBI:17245 ! has exposure stimulus carbon monoxide

[Term]
id: ECTO:0000231
name: exposure to chemical
def: "An exposure to chemical entity." []
synonym: "chemical entity exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24431 ! has exposure stimulus chemical entity
relationship: RO:0002309 CHEBI:24431 ! has exposure stimulus chemical entity

[Term]
id: ECTO:0000258
name: exposure to steroid hormone
def: "An exposure to steroid hormone." []
synonym: "steroid hormone exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26764 ! has exposure stimulus steroid hormone
relationship: RO:0002309 CHEBI:26764 ! has exposure stimulus steroid hormone

[Term]
id: ECTO:0000259
name: exposure to glucocorticoid
def: "An exposure to glucocorticoid." []
synonym: "glucocorticoid exposure" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
is_a: ECTO:0000258 ! exposure to steroid hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24261 ! has exposure stimulus glucocorticoid
relationship: RO:0002309 CHEBI:24261 ! has exposure stimulus glucocorticoid

[Term]
id: ECTO:0000371
name: exposure to oxygen molecular entity
def: "An exposure to oxygen molecular entity." []
synonym: "oxygen molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25806 ! has exposure stimulus oxygen molecular entity
relationship: RO:0002309 CHEBI:25806 ! has exposure stimulus oxygen molecular entity

[Term]
id: ECTO:0000439
name: exposure to formaldehyde
def: "An exposure to formaldehyde." []
synonym: "formaldehyde exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16842 ! has exposure stimulus formaldehyde
relationship: RO:0002309 CHEBI:16842 ! has exposure stimulus formaldehyde

[Term]
id: ECTO:0000481
name: exposure to transition element
def: "An exposure to transition element molecular entity." []
synonym: "transition element molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33497 ! has exposure stimulus transition element molecular entity
relationship: RO:0002309 CHEBI:33497 ! has exposure stimulus transition element molecular entity

[Term]
id: ECTO:0000485
name: exposure to chemical with biological effect
def: "An exposure to biological role." []
synonym: "biological role exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24432 ! has exposure stimulus biological role
relationship: RO:0002309 CHEBI:24432 ! has exposure stimulus biological role

[Term]
id: ECTO:0000486
name: exposure to chemical with application
def: "An exposure to application." []
synonym: "application exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33232 ! has exposure stimulus application
relationship: RO:0002309 CHEBI:33232 ! has exposure stimulus application

[Term]
id: ECTO:0000487
name: exposure to chemical with chemical role
def: "An exposure to chemical role." []
synonym: "chemical role exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51086 ! has exposure stimulus chemical role
relationship: RO:0002309 CHEBI:51086 ! has exposure stimulus chemical role

[Term]
id: ECTO:0000496
name: exposure to alkylating agent
def: "An exposure to alkylating agent." []
synonym: "alkylating agent exposure" EXACT []
is_a: ECTO:0000523 ! exposure to mutagen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22333 ! has exposure stimulus alkylating agent
relationship: RO:0002309 CHEBI:22333 ! has exposure stimulus alkylating agent

[Term]
id: ECTO:0000509
name: exposure to drug
def: "An exposure to drug." []
synonym: "drug exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23888 ! has exposure stimulus drug
relationship: RO:0002309 CHEBI:23888 ! has exposure stimulus drug

[Term]
id: ECTO:0000515
name: exposure to herbicide
def: "An exposure to herbicide." []
synonym: "herbicide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24527 ! has exposure stimulus herbicide
relationship: RO:0002309 CHEBI:24527 ! has exposure stimulus herbicide

[Term]
id: ECTO:0000516
name: exposure to hormone
def: "An exposure to hormone." []
synonym: "hormone exposure" EXACT []
is_a: ECTO:0000543 ! exposure to molecular messenger
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24621 ! has exposure stimulus hormone
relationship: RO:0002309 CHEBI:24621 ! has exposure stimulus hormone

[Term]
id: ECTO:0000522
name: exposure to mitochondrial respiratory-chain inhibitor
def: "An exposure to mitochondrial respiratory-chain inhibitor." []
synonym: "mitochondrial respiratory-chain inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25355 ! has exposure stimulus mitochondrial respiratory-chain inhibitor
relationship: RO:0002309 CHEBI:25355 ! has exposure stimulus mitochondrial respiratory-chain inhibitor

[Term]
id: ECTO:0000523
name: exposure to mutagen
def: "An exposure to mutagen." []
synonym: "mutagen exposure" EXACT []
is_a: ECTO:0000724 ! exposure to genotoxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25435 ! has exposure stimulus mutagen
relationship: RO:0002309 CHEBI:25435 ! has exposure stimulus mutagen

[Term]
id: ECTO:0000524
name: exposure to mycotoxin
def: "An exposure to mycotoxin." []
synonym: "mycotoxin exposure" EXACT []
is_a: ECTO:0000537 ! exposure to toxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25442 ! has exposure stimulus mycotoxin
relationship: RO:0002309 CHEBI:25442 ! has exposure stimulus mycotoxin

[Term]
id: ECTO:0000526
name: exposure to neurotransmitter
def: "An exposure to neurotransmitter." []
synonym: "neurotransmitter exposure" EXACT []
is_a: ECTO:0000543 ! exposure to molecular messenger
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25512 ! has exposure stimulus neurotransmitter
relationship: RO:0002309 CHEBI:25512 ! has exposure stimulus neurotransmitter

[Term]
id: ECTO:0000530
name: exposure to pesticide
def: "An exposure to pesticide." []
synonym: "pesticide exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25944 ! has exposure stimulus pesticide
relationship: RO:0002309 CHEBI:25944 ! has exposure stimulus pesticide

[Term]
id: ECTO:0000537
name: exposure to toxin
def: "An exposure to toxin." []
synonym: "toxin exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27026 ! has exposure stimulus toxin
relationship: RO:0002309 CHEBI:27026 ! has exposure stimulus toxin

[Term]
id: ECTO:0000543
name: exposure to molecular messenger
def: "An exposure to molecular messenger." []
synonym: "molecular messenger exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33280 ! has exposure stimulus molecular messenger
relationship: RO:0002309 CHEBI:33280 ! has exposure stimulus molecular messenger

[Term]
id: ECTO:0000544
name: exposure to antimicrobial agent
def: "An exposure to antimicrobial agent." []
synonym: "antimicrobial agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33281 ! has exposure stimulus antimicrobial agent
relationship: RO:0002309 CHEBI:33281 ! has exposure stimulus antimicrobial agent

[Term]
id: ECTO:0000557
name: exposure to inhibitor
def: "An exposure to inhibitor." []
synonym: "inhibitor exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35222 ! has exposure stimulus inhibitor
relationship: RO:0002309 CHEBI:35222 ! has exposure stimulus inhibitor

[Term]
id: ECTO:0000590
name: exposure to vasodilator agent
def: "An exposure to vasodilator agent." []
synonym: "vasodilator agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35620 ! has exposure stimulus vasodilator agent
relationship: RO:0002309 CHEBI:35620 ! has exposure stimulus vasodilator agent

[Term]
id: ECTO:0000637
name: exposure to EC 1.9.3.1 (cytochrome c oxidase) inhibitor
def: "An exposure to EC 1.9.3.1 (cytochrome c oxidase) inhibitor." []
synonym: "EC 1.9.3.1 (cytochrome c oxidase) inhibitor exposure" EXACT []
is_a: ECTO:0000522 ! exposure to mitochondrial respiratory-chain inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38500 ! has exposure stimulus EC 1.9.3.1 (cytochrome c oxidase) inhibitor
relationship: RO:0002309 CHEBI:38500 ! has exposure stimulus EC 1.9.3.1 (cytochrome c oxidase) inhibitor

[Term]
id: ECTO:0000650
name: exposure to Bronsted acid
def: "An exposure to Bronsted acid." []
synonym: "Bronsted acid exposure" EXACT []
is_a: ECTO:9002146 ! exposure to acids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39141 ! has exposure stimulus Bronsted acid
relationship: RO:0002309 CHEBI:39141 ! has exposure stimulus Bronsted acid

[Term]
id: ECTO:0000657
name: exposure to disinfectant
def: "An exposure to disinfectant." []
synonym: "disinfectant exposure" EXACT []
is_a: ECTO:0000544 ! exposure to antimicrobial agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48219 ! has exposure stimulus disinfectant
relationship: RO:0002309 CHEBI:48219 ! has exposure stimulus disinfectant

[Term]
id: ECTO:0000672
name: exposure to agonist
def: "An exposure to agonist." []
synonym: "agonist exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48705 ! has exposure stimulus agonist
relationship: RO:0002309 CHEBI:48705 ! has exposure stimulus agonist

[Term]
id: ECTO:0000689
name: exposure to P450 inhibitor
def: "An exposure to P450 inhibitor." []
synonym: "P450 inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50183 ! has exposure stimulus P450 inhibitor
relationship: RO:0002309 CHEBI:50183 ! has exposure stimulus P450 inhibitor

[Term]
id: ECTO:0000699
name: exposure to probe
def: "An exposure to probe." []
synonym: "probe exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50406 ! has exposure stimulus probe
relationship: RO:0002309 CHEBI:50406 ! has exposure stimulus probe

[Term]
id: ECTO:0000724
name: exposure to genotoxin
def: "An exposure to genotoxin." []
synonym: "genotoxin exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50902 ! has exposure stimulus genotoxin
relationship: RO:0002309 CHEBI:50902 ! has exposure stimulus genotoxin

[Term]
id: ECTO:0000725
name: exposure to carcinogenic agent
def: "An exposure to carcinogenic agent." []
synonym: "carcinogenic agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50903 ! has exposure stimulus carcinogenic agent
relationship: RO:0002309 CHEBI:50903 ! has exposure stimulus carcinogenic agent

[Term]
id: ECTO:0000726
name: exposure to allergen
def: "An exposure to allergen." []
synonym: "allergen exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50904 ! has exposure stimulus allergen
relationship: RO:0002309 CHEBI:50904 ! has exposure stimulus allergen

[Term]
id: ECTO:0000730
name: exposure to neurotoxin
def: "An exposure to neurotoxin." []
synonym: "neurotoxin exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50910 ! has exposure stimulus neurotoxin
relationship: RO:0002309 CHEBI:50910 ! has exposure stimulus neurotoxin

[Term]
id: ECTO:0000738
name: exposure to ligand
def: "An exposure to ligand." []
synonym: "ligand exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52214 ! has exposure stimulus ligand
relationship: RO:0002309 CHEBI:52214 ! has exposure stimulus ligand

[Term]
id: ECTO:0000750
name: exposure to biomarker
def: "An exposure to biomarker." []
synonym: "biomarker exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59163 ! has exposure stimulus biomarker
relationship: RO:0002309 CHEBI:59163 ! has exposure stimulus biomarker

[Term]
id: ECTO:0000776
name: exposure to signalling molecule
def: "An exposure to signalling molecule." []
synonym: "signalling molecule exposure" EXACT []
is_a: ECTO:0000543 ! exposure to molecular messenger
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62488 ! has exposure stimulus signalling molecule
relationship: RO:0002309 CHEBI:62488 ! has exposure stimulus signalling molecule

[Term]
id: ECTO:0000922
name: exposure to EC 3.5.1.4 (amidase) inhibitor
def: "An exposure to EC 3.5.1.4 (amidase) inhibitor." []
synonym: "EC 3.5.1.4 (amidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77941 ! has exposure stimulus EC 3.5.1.4 (amidase) inhibitor
relationship: RO:0002309 CHEBI:77941 ! has exposure stimulus EC 3.5.1.4 (amidase) inhibitor

[Term]
id: ECTO:0000931
name: exposure to environmental contaminant
def: "An exposure to environmental contaminant." []
synonym: "environmental contaminant exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78298 ! has exposure stimulus environmental contaminant
relationship: RO:0002309 CHEBI:78298 ! has exposure stimulus environmental contaminant

[Term]
id: ECTO:0000979
name: exposure to temperature of environmental surroundings
def: "A exposure event involving the interaction of an exposure receptor to temperature of environmental material." []
synonym: "temperature of environmental material exposure" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:09200000 ! has exposure stimulus temperature of environmental material
relationship: RO:0002309 ENVO:09200000 ! has exposure stimulus temperature of environmental material

[Term]
id: ECTO:0000980
name: exposure to temperature of air in surroundings
def: "A exposure event involving the interaction of an exposure receptor to temperature of air." []
synonym: "temperature of air exposure" EXACT []
is_a: ECTO:0000979 ! exposure to temperature of environmental surroundings
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:09200001 ! has exposure stimulus temperature of air
relationship: RO:0002309 ENVO:09200001 ! has exposure stimulus temperature of air

[Term]
id: ECTO:0001055
name: exposure to decreased air temperature
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of temperature of air." []
synonym: "exposure to decreased amount in temperature of air" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:0001057
name: exposure to decreased temperature
def: "A exposure event involving the interaction of an exposure receptor to decreased temperature." []
synonym: "decreased temperature exposure" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001306 ! has exposure stimulus decreased temperature
relationship: RO:0002309 PATO:0001306 ! has exposure stimulus decreased temperature

[Term]
id: ECTO:0001082
name: exposure to alcohol consumption
def: "An exposure event involving Alcohol Consumption" []
synonym: "Alcohol Consumption exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C16273 ! has exposure stimulus Alcohol Consumption
relationship: RO:0002309 NCIT:C16273 ! has exposure stimulus Alcohol Consumption

[Term]
id: ECTO:0001108
name: exposure to aflatoxin
def: "An exposure to aflatoxin." []
synonym: "aflatoxin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22271 ! has exposure stimulus aflatoxin
relationship: RO:0002309 CHEBI:22271 ! has exposure stimulus aflatoxin

[Term]
id: ECTO:0001152
name: exposure to organochlorine compound
def: "An exposure to organochlorine compound." []
synonym: "organochlorine compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000077 ! exposure to chlorine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36683 ! has exposure stimulus organochlorine compound
relationship: RO:0002309 CHEBI:36683 ! has exposure stimulus organochlorine compound

[Term]
id: ECTO:0001566
name: exposure to cadmium
def: "An exposure to cadmium molecular entity." []
synonym: "cadmium molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22978 ! has exposure stimulus cadmium molecular entity
relationship: RO:0002309 CHEBI:22978 ! has exposure stimulus cadmium molecular entity

[Term]
id: ECTO:0001571
name: exposure to mercury
def: "An exposure to mercury molecular entity." []
synonym: "mercury molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25196 ! has exposure stimulus mercury molecular entity
relationship: RO:0002309 CHEBI:25196 ! has exposure stimulus mercury molecular entity

[Term]
id: ECTO:0001591
name: exposure to occupation
def: "An exposure event involving Occupation" []
synonym: "Occupation exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C25193 ! has exposure stimulus Occupation
relationship: RO:0002309 NCIT:C25193 ! has exposure stimulus Occupation

[Term]
id: ECTO:0001659
name: exposure to chloroacetic acid
def: "An exposure to chloroacetic acid." []
synonym: "chloroacetic acid exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002412 ! exposure to haloacetic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27869 ! has exposure stimulus chloroacetic acid
relationship: RO:0002309 CHEBI:27869 ! has exposure stimulus chloroacetic acid

[Term]
id: ECTO:0002002
name: exposure to steroid
def: "An exposure to steroid." []
synonym: "steroid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35341 ! has exposure stimulus steroid
relationship: RO:0002309 CHEBI:35341 ! has exposure stimulus steroid

[Term]
id: ECTO:0010000
name: exposure to environmental quality
def: "A exposure event involving the interaction of an exposure receptor to quality." []
synonym: "quality exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0000001 ! has exposure stimulus quality
relationship: RO:0002309 PATO:0000001 ! has exposure stimulus quality

[Term]
id: ECTO:0010001
name: exposure to qualitative environmental quality
def: "A exposure event involving the interaction of an exposure receptor to qualitative." []
synonym: "qualitative exposure" EXACT []
is_a: ECTO:0010000 ! exposure to environmental quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0000068 ! has exposure stimulus qualitative
relationship: RO:0002309 PATO:0000068 ! has exposure stimulus qualitative

[Term]
id: ECTO:0010002
name: exposure to environmental process quality
def: "A exposure event involving the interaction of an exposure receptor to process quality." []
synonym: "process quality exposure" EXACT []
is_a: ECTO:0010000 ! exposure to environmental quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001236 ! has exposure stimulus process quality
relationship: RO:0002309 PATO:0001236 ! has exposure stimulus process quality

[Term]
id: ECTO:0010003
name: exposure to environmental physical object quality
def: "A exposure event involving the interaction of an exposure receptor to physical object quality." []
synonym: "physical object quality exposure" EXACT []
is_a: ECTO:0010000 ! exposure to environmental quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001241 ! has exposure stimulus physical object quality
relationship: RO:0002309 PATO:0001241 ! has exposure stimulus physical object quality

[Term]
id: ECTO:0010004
name: exposure to acidity of soil
def: "A exposure event involving the interaction of an exposure receptor to acidity of soil." []
synonym: "acidity of soil exposure" EXACT []
is_a: ECTO:0010000 ! exposure to environmental quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:09200010 ! has exposure stimulus acidity of soil
relationship: RO:0002309 ENVO:09200010 ! has exposure stimulus acidity of soil

[Term]
id: ECTO:0010005
name: exposure to acidic environment
def: "A exposure event involving the interaction of an exposure receptor to acidic environment." []
synonym: "acidic environment exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000315 ! has exposure stimulus acidic environment
relationship: RO:0002309 ENVO:01000315 ! has exposure stimulus acidic environment

[Term]
id: ECTO:0010006
name: exposure to elevation
def: "A exposure event involving the interaction of an exposure receptor to elevation." []
synonym: "elevation exposure" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001687 ! has exposure stimulus elevation
relationship: RO:0002309 PATO:0001687 ! has exposure stimulus elevation

[Term]
id: ECTO:0010007
name: exposure to humidity
def: "A exposure event involving the interaction of an exposure receptor to humidity." []
synonym: "humidity exposure" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0015009 ! has exposure stimulus humidity
relationship: RO:0002309 PATO:0015009 ! has exposure stimulus humidity

[Term]
id: ECTO:0010008
name: exposure to salinity
def: "A exposure event involving the interaction of an exposure receptor to salinity." []
synonym: "salinity exposure" EXACT []
is_a: ECTO:0010000 ! exposure to environmental quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0085001 ! has exposure stimulus salinity
relationship: RO:0002309 PATO:0085001 ! has exposure stimulus salinity

[Term]
id: ECTO:0010009
name: exposure to tension
def: "A exposure event involving the interaction of an exposure receptor to tension." []
synonym: "tension exposure" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0002284 ! has exposure stimulus tension
relationship: RO:0002309 PATO:0002284 ! has exposure stimulus tension

[Term]
id: ECTO:0010010
name: exposure to increased osmolarity
def: "A exposure event involving the interaction of an exposure receptor to increased osmolarity." []
synonym: "increased osmolarity exposure" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001657 ! has exposure stimulus increased osmolarity
relationship: RO:0002309 PATO:0001657 ! has exposure stimulus increased osmolarity

[Term]
id: ECTO:0010011
name: exposure to temperature of sea surface
def: "A exposure event involving the interaction of an exposure receptor to temperature of sea surface." []
synonym: "temperature of sea surface exposure" EXACT []
is_a: ECTO:1000043 ! exposure to temperature of water
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:04000002 ! has exposure stimulus temperature of sea surface
relationship: RO:0002309 ENVO:04000002 ! has exposure stimulus temperature of sea surface

[Term]
id: ECTO:0020000
name: exposure to automotive occupations
def: "An exposure event involving Automotive Occupations" []
synonym: "Automotive Occupations exposure" EXACT []
is_a: ECTO:0001591 ! exposure to occupation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C103933 ! has exposure stimulus Automotive Occupations
relationship: RO:0002309 NCIT:C103933 ! has exposure stimulus Automotive Occupations

[Term]
id: ECTO:0030000
name: obsolete exposure to a diet
is_obsolete: true

[Term]
id: ECTO:0030001
name: obsolete exposure to high vegetable diet
is_obsolete: true

[Term]
id: ECTO:0050000
name: exposure to high-carbohydrate diet
def: "An exposure event involving high-carbohydrate diet" []
synonym: "high-carbohydrate diet exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ONS:1000039 ! has exposure stimulus high-carbohydrate diet
relationship: RO:0002309 ONS:1000039 ! has exposure stimulus high-carbohydrate diet

[Term]
id: ECTO:0050001
name: exposure to mediterranean diet
def: "An exposure event involving mediterranean diet" []
synonym: "mediterranean diet exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ONS:1000038 ! has exposure stimulus mediterranean diet
relationship: RO:0002309 ONS:1000038 ! has exposure stimulus mediterranean diet

[Term]
id: ECTO:0070000
name: exposure to probiotic or bacteria supplement via ingestion
def: "An exposure to probiotic or bacteria supplement via ingestion." []
synonym: "probiotic or bacteria supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03401308 ! has exposure stimulus probiotic or bacteria supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03401308 ! has exposure stimulus probiotic or bacteria supplement

[Term]
id: ECTO:0070001
name: exposure to skim milk via ingestion
def: "An exposure to skim milk (pasteurized, vitamin A and D fortified) via ingestion." []
synonym: "skim milk (pasteurized, vitamin A and D fortified) exposure via ingestion" EXACT []
is_a: ECTO:0070204 ! exposure to cow milk (liquid) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311235 ! has exposure stimulus skim milk (pasteurized, vitamin A and D fortified)
relationship: RO:0002309 FOODON:03311235 ! has exposure stimulus skim milk (pasteurized, vitamin A and D fortified)

[Term]
id: ECTO:0070002
name: exposure to lowfat milk via ingestion
def: "An exposure to lowfat cow milk (1% fat) via ingestion." []
synonym: "lowfat cow milk (1% fat) exposure via ingestion" EXACT []
is_a: ECTO:0070204 ! exposure to cow milk (liquid) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002815 ! has exposure stimulus lowfat cow milk (1% fat)
relationship: RO:0002309 FOODON:00002815 ! has exposure stimulus lowfat cow milk (1% fat)

[Term]
id: ECTO:0070003
name: exposure to whole milk via ingestion
def: "An exposure to cow whole milk 3.5% fat via ingestion." []
synonym: "cow whole milk 3.5% fat exposure via ingestion" EXACT []
is_a: ECTO:0070204 ! exposure to cow milk (liquid) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310780 ! has exposure stimulus cow whole milk 3.5% fat
relationship: RO:0002309 FOODON:03310780 ! has exposure stimulus cow whole milk 3.5% fat

[Term]
id: ECTO:0070004
name: exposure to almond milk via ingestion
def: "An exposure to almond milk via ingestion." []
synonym: "almond milk exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003157 ! has exposure stimulus almond milk
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003157 ! has exposure stimulus almond milk

[Term]
id: ECTO:0070005
name: exposure to soybean milk via ingestion
def: "An exposure to soybean milk via ingestion." []
synonym: "soybean milk exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305289 ! has exposure stimulus soybean milk
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03305289 ! has exposure stimulus soybean milk

[Term]
id: ECTO:0070006
name: exposure to milk beverage analog via ingestion
def: "An exposure to milk beverage analog via ingestion." []
synonym: "milk beverage analog exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002034 ! has exposure stimulus milk beverage analog
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002034 ! has exposure stimulus milk beverage analog

[Term]
id: ECTO:0070007
name: exposure to heavy cream via ingestion
def: "An exposure to heavy cream via ingestion." []
synonym: "heavy cream exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310795 ! has exposure stimulus heavy cream
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310795 ! has exposure stimulus heavy cream

[Term]
id: ECTO:0070008
name: exposure to imitation half and half via ingestion
def: "An exposure to imitation half and half via ingestion." []
synonym: "imitation half and half exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03304468 ! has exposure stimulus imitation half and half
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03304468 ! has exposure stimulus imitation half and half

[Term]
id: ECTO:0070009
name: exposure to frozen yogurt via ingestion
def: "An exposure to frozen yogurt via ingestion." []
synonym: "frozen yogurt exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03307445 ! has exposure stimulus frozen yogurt
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03307445 ! has exposure stimulus frozen yogurt

[Term]
id: ECTO:0070010
name: exposure to ice cream via ingestion
def: "An exposure to ice cream food product via ingestion." []
synonym: "ice cream food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001045 ! has exposure stimulus ice cream food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001045 ! has exposure stimulus ice cream food product

[Term]
id: ECTO:0070011
name: exposure to butter via ingestion
def: "An exposure to butter via ingestion." []
synonym: "butter exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310351 ! has exposure stimulus butter
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310351 ! has exposure stimulus butter

[Term]
id: ECTO:0070012
name: exposure to margarine via ingestion
def: "An exposure to margarine via ingestion." []
synonym: "margarine exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301672 ! has exposure stimulus margarine
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301672 ! has exposure stimulus margarine

[Term]
id: ECTO:0070013
name: exposure to butter spread via ingestion
def: "An exposure to butter blend spread via ingestion." []
synonym: "butter blend spread exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303711 ! has exposure stimulus butter blend spread
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303711 ! has exposure stimulus butter blend spread

[Term]
id: ECTO:0070014
name: exposure to non fat yogurt via ingestion
def: "An exposure to yogurt (nonfat) via ingestion." []
synonym: "yogurt (nonfat) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305085 ! has exposure stimulus yogurt (nonfat)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03305085 ! has exposure stimulus yogurt (nonfat)

[Term]
id: ECTO:0070015
name: exposure to lowfat yogurt via ingestion
def: "An exposure to yogurt (lowfat) via ingestion." []
synonym: "yogurt (lowfat) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03307444 ! has exposure stimulus yogurt (lowfat)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03307444 ! has exposure stimulus yogurt (lowfat)

[Term]
id: ECTO:0070016
name: exposure to regular yogurt via ingestion
def: "An exposure to yogurt (plain) via ingestion." []
synonym: "yogurt (plain) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301502 ! has exposure stimulus yogurt (plain)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301502 ! has exposure stimulus yogurt (plain)

[Term]
id: ECTO:0070017
name: exposure to cottage cheese via ingestion
def: "An exposure to cottage cheese (lowfat) via ingestion." []
synonym: "cottage cheese (lowfat) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303720 ! has exposure stimulus cottage cheese (lowfat)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303720 ! has exposure stimulus cottage cheese (lowfat)

[Term]
id: ECTO:0070018
name: exposure to cream cheese via ingestion
def: "An exposure to cream cheese via ingestion." []
synonym: "cream cheese exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301889 ! has exposure stimulus cream cheese
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301889 ! has exposure stimulus cream cheese

[Term]
id: ECTO:0070020
name: exposure to lowfat cheese via ingestion
def: "An exposure to cheese (lowfat) via ingestion." []
synonym: "cheese (lowfat) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303902 ! has exposure stimulus cheese (lowfat)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303902 ! has exposure stimulus cheese (lowfat)

[Term]
id: ECTO:0070021
name: exposure to cheese (natural) via ingestion
def: "An exposure to cheese (natural) via ingestion." []
synonym: "cheese (natural) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303504 ! has exposure stimulus cheese (natural)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303504 ! has exposure stimulus cheese (natural)

[Term]
id: ECTO:0070022
name: exposure to apple via ingestion
def: "An exposure to apple via ingestion." []
synonym: "apple exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002473 ! has exposure stimulus apple
relationship: RO:0002309 FOODON:00002473 ! has exposure stimulus apple

[Term]
id: ECTO:0070023
name: exposure to avocado via ingestion
def: "An exposure to avocado (raw) via ingestion." []
synonym: "avocado (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070182 ! exposure to stone fruit via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305236 ! has exposure stimulus avocado (raw)
relationship: RO:0002309 FOODON:03305236 ! has exposure stimulus avocado (raw)

[Term]
id: ECTO:0070024
name: exposure to banana via ingestion
def: "An exposure to banana via ingestion." []
synonym: "banana exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00004183 ! has exposure stimulus banana
relationship: RO:0002309 FOODON:00004183 ! has exposure stimulus banana

[Term]
id: ECTO:0070025
name: exposure to blueberries via ingestion
def: "An exposure to blueberry (raw) via ingestion." []
synonym: "blueberry (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302045 ! has exposure stimulus blueberry (raw)
relationship: RO:0002309 FOODON:03302045 ! has exposure stimulus blueberry (raw)

[Term]
id: ECTO:0070026
name: exposure to cantaloupe via ingestion
def: "An exposure to cantaloupe (raw) via ingestion." []
synonym: "cantaloupe (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302805 ! has exposure stimulus cantaloupe (raw)
relationship: RO:0002309 FOODON:03302805 ! has exposure stimulus cantaloupe (raw)

[Term]
id: ECTO:0070027
name: exposure to grapes via ingestion
def: "An exposure to grape (raw) via ingestion." []
synonym: "grape (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301123 ! has exposure stimulus grape (raw)
relationship: RO:0002309 FOODON:03301123 ! has exposure stimulus grape (raw)

[Term]
id: ECTO:0070028
name: exposure to grapefruit via ingestion
def: "An exposure to grapefruit (raw) via ingestion." []
synonym: "grapefruit (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070214 ! exposure to citrus fruit (raw) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301702 ! has exposure stimulus grapefruit (raw)
relationship: RO:0002309 FOODON:03301702 ! has exposure stimulus grapefruit (raw)

[Term]
id: ECTO:0070029
name: exposure to navel orange via ingestion
def: "An exposure to navel orange (raw) via ingestion." []
synonym: "navel orange (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070214 ! exposure to citrus fruit (raw) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002511 ! has exposure stimulus navel orange (raw)
relationship: RO:0002309 FOODON:00002511 ! has exposure stimulus navel orange (raw)

[Term]
id: ECTO:0070030
name: exposure to peach via ingestion
def: "An exposure to peach (raw) via ingestion." []
synonym: "peach (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070182 ! exposure to stone fruit via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301719 ! has exposure stimulus peach (raw)
relationship: RO:0002309 FOODON:03301719 ! has exposure stimulus peach (raw)

[Term]
id: ECTO:0070031
name: exposure to plum via ingestion
def: "An exposure to plum (raw) via ingestion." []
synonym: "plum (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070182 ! exposure to stone fruit via ingestion
is_a: ECTO:0070220 ! exposure to fruit food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301580 ! has exposure stimulus plum (raw)
relationship: RO:0002309 FOODON:03301580 ! has exposure stimulus plum (raw)

[Term]
id: ECTO:0070032
name: exposure to apricot via ingestion
def: "An exposure to apricot (raw) via ingestion." []
synonym: "apricot (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070182 ! exposure to stone fruit via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301701 ! has exposure stimulus apricot (raw)
relationship: RO:0002309 FOODON:03301701 ! has exposure stimulus apricot (raw)

[Term]
id: ECTO:0070033
name: exposure to pear via ingestion
def: "An exposure to pear (raw) via ingestion." []
synonym: "pear (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301724 ! has exposure stimulus pear (raw)
relationship: RO:0002309 FOODON:03301724 ! has exposure stimulus pear (raw)

[Term]
id: ECTO:0070034
name: exposure to raspberry via ingestion
def: "An exposure to raspberry (raw) via ingestion." []
synonym: "raspberry (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03307119 ! has exposure stimulus raspberry (raw)
relationship: RO:0002309 FOODON:03307119 ! has exposure stimulus raspberry (raw)

[Term]
id: ECTO:0070035
name: exposure to strawberry via ingestion
def: "An exposure to strawberry (raw) via ingestion." []
synonym: "strawberry (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301722 ! has exposure stimulus strawberry (raw)
relationship: RO:0002309 FOODON:03301722 ! has exposure stimulus strawberry (raw)

[Term]
id: ECTO:0070036
name: exposure to tomato via ingestion
def: "An exposure to tomato via ingestion." []
synonym: "tomato exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301453 ! has exposure stimulus tomato
relationship: RO:0002309 FOODON:03301453 ! has exposure stimulus tomato

[Term]
id: ECTO:0070037
name: exposure to tomato juice via ingestion
def: "An exposure to tomato juice via ingestion." []
synonym: "tomato juice exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301454 ! has exposure stimulus tomato juice
relationship: RO:0002309 FOODON:03301454 ! has exposure stimulus tomato juice

[Term]
id: ECTO:0070038
name: exposure to tomato sauce via ingestion
def: "An exposure to tomato sauce via ingestion." []
synonym: "tomato sauce exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301217 ! has exposure stimulus tomato sauce
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301217 ! has exposure stimulus tomato sauce

[Term]
id: ECTO:0070039
name: exposure to watermelon via ingestion
def: "An exposure to watermelon (raw) via ingestion." []
synonym: "watermelon (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301040 ! has exposure stimulus watermelon (raw)
relationship: RO:0002309 FOODON:03301040 ! has exposure stimulus watermelon (raw)

[Term]
id: ECTO:0070040
name: exposure to bean via ingestion
def: "An exposure to bean via ingestion." []
synonym: "bean exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002753 ! has exposure stimulus bean
relationship: RO:0002309 FOODON:00002753 ! has exposure stimulus bean

[Term]
id: ECTO:0070041
name: exposure to lentil via ingestion
def: "An exposure to lentil via ingestion." []
synonym: "lentil exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310641 ! has exposure stimulus lentil
relationship: RO:0002309 FOODON:03310641 ! has exposure stimulus lentil

[Term]
id: ECTO:0070042
name: exposure to bell pepper via ingestion
def: "An exposure to bell pepper via ingestion." []
synonym: "bell pepper exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003546 ! has exposure stimulus bell pepper
relationship: RO:0002309 FOODON:00003546 ! has exposure stimulus bell pepper

[Term]
id: ECTO:0070043
name: exposure to broccoli via ingestion
def: "An exposure to broccoli floret (raw) via ingestion." []
synonym: "broccoli floret (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301713 ! has exposure stimulus broccoli floret (raw)
relationship: RO:0002309 FOODON:03301713 ! has exposure stimulus broccoli floret (raw)

[Term]
id: ECTO:0070044
name: exposure to brussels sprout via ingestion
def: "An exposure to brussels sprout via ingestion." []
synonym: "brussels sprout exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311885 ! has exposure stimulus brussels sprout
relationship: RO:0002309 FOODON:03311885 ! has exposure stimulus brussels sprout

[Term]
id: ECTO:0070045
name: exposure to cabbage via ingestion
def: "An exposure to cabbage head via ingestion." []
synonym: "cabbage head exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003406 ! has exposure stimulus cabbage head
relationship: RO:0002309 FOODON:00003406 ! has exposure stimulus cabbage head

[Term]
id: ECTO:0070046
name: exposure to carrot via ingestion
def: "An exposure to carrot root via ingestion." []
synonym: "carrot root exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003408 ! has exposure stimulus carrot root
relationship: RO:0002309 FOODON:00003408 ! has exposure stimulus carrot root

[Term]
id: ECTO:0070047
name: exposure to cauliflower via ingestion
def: "An exposure to cauliflower floret via ingestion." []
synonym: "cauliflower floret exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003410 ! has exposure stimulus cauliflower floret
relationship: RO:0002309 FOODON:00003410 ! has exposure stimulus cauliflower floret

[Term]
id: ECTO:0070048
name: exposure to corn via ingestion
def: "An exposure to corn kernel via ingestion." []
synonym: "corn kernel exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03317387 ! has exposure stimulus corn kernel
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03317387 ! has exposure stimulus corn kernel

[Term]
id: ECTO:0070049
name: exposure to eggplant via ingestion
def: "An exposure to eggplant via ingestion." []
synonym: "eggplant exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003618 ! has exposure stimulus eggplant
relationship: RO:0002309 FOODON:00003618 ! has exposure stimulus eggplant

[Term]
id: ECTO:0070050
name: exposure to zucchini via ingestion
def: "An exposure to zucchini squash via ingestion." []
synonym: "zucchini squash exposure via ingestion" EXACT []
is_a: ECTO:0070051 ! exposure to squash via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310943 ! has exposure stimulus zucchini squash
relationship: RO:0002309 FOODON:03310943 ! has exposure stimulus zucchini squash

[Term]
id: ECTO:0070051
name: exposure to squash via ingestion
def: "An exposure to squash via ingestion." []
synonym: "squash exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003539 ! has exposure stimulus squash
relationship: RO:0002309 FOODON:00003539 ! has exposure stimulus squash

[Term]
id: ECTO:0070052
name: exposure to kale via ingestion
def: "An exposure to kale leaf (raw) via ingestion." []
synonym: "kale leaf (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070184 ! exposure to plant leaf vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03304859 ! has exposure stimulus kale leaf (raw)
relationship: RO:0002309 FOODON:03304859 ! has exposure stimulus kale leaf (raw)

[Term]
id: ECTO:0070053
name: exposure to collard greens via ingestion
def: "An exposure to collard leaf (raw) via ingestion." []
synonym: "collard leaf (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03304860 ! has exposure stimulus collard leaf (raw)
relationship: RO:0002309 FOODON:03304860 ! has exposure stimulus collard leaf (raw)

[Term]
id: ECTO:0070054
name: exposure to mustard greens via ingestion
def: "An exposure to mustard greens via ingestion." []
synonym: "mustard greens exposure via ingestion" EXACT []
is_a: ECTO:0070184 ! exposure to plant leaf vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002684 ! has exposure stimulus mustard greens
relationship: RO:0002309 FOODON:00002684 ! has exposure stimulus mustard greens

[Term]
id: ECTO:0070055
name: exposure to swiss chard via ingestion
def: "An exposure to swiss chard leaf via ingestion." []
synonym: "swiss chard leaf exposure via ingestion" EXACT []
is_a: ECTO:0070184 ! exposure to plant leaf vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003631 ! has exposure stimulus swiss chard leaf
relationship: RO:0002309 FOODON:00003631 ! has exposure stimulus swiss chard leaf

[Term]
id: ECTO:0070056
name: exposure to onion via ingestion
def: "An exposure to onion (raw) via ingestion." []
synonym: "onion (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301704 ! has exposure stimulus onion (raw)
relationship: RO:0002309 FOODON:03301704 ! has exposure stimulus onion (raw)

[Term]
id: ECTO:0070057
name: exposure to peas via ingestion
def: "An exposure to pea via ingestion." []
synonym: "pea exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301300 ! has exposure stimulus pea
relationship: RO:0002309 FOODON:03301300 ! has exposure stimulus pea

[Term]
id: ECTO:0070058
name: exposure to lima bean via ingestion
def: "An exposure to baby lima bean via ingestion." []
synonym: "baby lima bean exposure via ingestion" EXACT []
is_a: ECTO:0070040 ! exposure to bean via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302061 ! has exposure stimulus baby lima bean
relationship: RO:0002309 FOODON:03302061 ! has exposure stimulus baby lima bean

[Term]
id: ECTO:0070059
name: exposure to spinach leaf (whole) via ingestion
def: "An exposure to spinach leaf via ingestion." []
synonym: "spinach leaf exposure via ingestion" EXACT []
is_a: ECTO:0070184 ! exposure to plant leaf vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003495 ! has exposure stimulus spinach leaf
relationship: RO:0002309 FOODON:00003495 ! has exposure stimulus spinach leaf

[Term]
id: ECTO:0070060
name: exposure to spinach leaf (whole, raw) via ingestion
def: "An exposure to spinach leaf (raw) via ingestion." []
synonym: "spinach leaf (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070059 ! exposure to spinach leaf (whole) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301716 ! has exposure stimulus spinach leaf (raw)
relationship: RO:0002309 FOODON:03301716 ! has exposure stimulus spinach leaf (raw)

[Term]
id: ECTO:0070061
name: exposure to saccharin via ingestion
def: "An exposure to saccharin via ingestion." []
synonym: "saccharin exposure via ingestion" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000597 ! exposure to saccharin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:32111 ! has exposure stimulus saccharin

[Term]
id: ECTO:0070062
name: exposure to green bean via ingestion
def: "An exposure to green bean pod via ingestion." []
synonym: "green bean pod exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305806 ! has exposure stimulus green bean pod
relationship: RO:0002309 FOODON:03305806 ! has exposure stimulus green bean pod

[Term]
id: ECTO:0070063
name: exposure to tofu via ingestion
def: "An exposure to tofu food product via ingestion." []
synonym: "tofu food product exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03309664 ! has exposure stimulus tofu food product
relationship: RO:0002309 FOODON:03309664 ! has exposure stimulus tofu food product

[Term]
id: ECTO:0070064
name: exposure to vegetarian burger via ingestion
def: "An exposure to vegetarian burger via ingestion." []
synonym: "vegetarian burger exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003177 ! has exposure stimulus vegetarian burger
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003177 ! has exposure stimulus vegetarian burger

[Term]
id: ECTO:0070065
name: exposure to miso via ingestion
def: "An exposure to miso via ingestion." []
synonym: "miso exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003208 ! has exposure stimulus miso
relationship: RO:0002309 FOODON:00003208 ! has exposure stimulus miso

[Term]
id: ECTO:0070066
name: exposure to soybean via ingestion
def: "An exposure to soybean via ingestion." []
synonym: "soybean exposure via ingestion" EXACT []
is_a: ECTO:0070040 ! exposure to bean via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301415 ! has exposure stimulus soybean
relationship: RO:0002309 FOODON:03301415 ! has exposure stimulus soybean

[Term]
id: ECTO:0070067
name: exposure to winter squash via ingestion
def: "An exposure to squash (raw) via ingestion." []
synonym: "squash (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070051 ! exposure to squash via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301577 ! has exposure stimulus squash (raw)
relationship: RO:0002309 FOODON:03301577 ! has exposure stimulus squash (raw)

[Term]
id: ECTO:0070068
name: exposure to yam via ingestion
def: "An exposure to yam via ingestion." []
synonym: "yam exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003448 ! has exposure stimulus yam
relationship: RO:0002309 FOODON:00003448 ! has exposure stimulus yam

[Term]
id: ECTO:0070069
name: exposure to sweet potato via ingestion
def: "An exposure to sweet potato via ingestion." []
synonym: "sweet potato exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003445 ! has exposure stimulus sweet potato
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003445 ! has exposure stimulus sweet potato

[Term]
id: ECTO:0070070
name: exposure to egg via ingestion
def: "An exposure to chicken egg via ingestion." []
synonym: "chicken egg exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03316061 ! has exposure stimulus chicken egg
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03316061 ! has exposure stimulus chicken egg

[Term]
id: ECTO:0070071
name: exposure to hotdog via ingestion
def: "An exposure to hot dog via ingestion." []
synonym: "hot dog exposure via ingestion" EXACT []
is_a: ECTO:0070084 ! exposure to processed meat food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001009 ! has exposure stimulus hot dog
relationship: RO:0002309 FOODON:00001009 ! has exposure stimulus hot dog

[Term]
id: ECTO:0070072
name: exposure to pork sausage via ingestion
def: "An exposure to pork sausage (oven-cooked) via ingestion." []
synonym: "pork sausage (oven-cooked) exposure via ingestion" EXACT []
is_a: ECTO:0070078 ! exposure to luncheon meat via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311131 ! has exposure stimulus pork sausage (oven-cooked)
relationship: RO:0002309 FOODON:03311131 ! has exposure stimulus pork sausage (oven-cooked)

[Term]
id: ECTO:0070073
name: exposure to chicken frankfurter via ingestion
def: "An exposure to chicken frankfurter via ingestion." []
synonym: "chicken frankfurter exposure via ingestion" EXACT []
is_a: ECTO:0070071 ! exposure to hotdog via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310576 ! has exposure stimulus chicken frankfurter
relationship: RO:0002309 FOODON:03310576 ! has exposure stimulus chicken frankfurter

[Term]
id: ECTO:0070074
name: exposure to turkey sausage via ingestion
def: "An exposure to turkey sausage via ingestion." []
synonym: "turkey sausage exposure via ingestion" EXACT []
is_a: ECTO:0070084 ! exposure to processed meat food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003297 ! has exposure stimulus turkey sausage
relationship: RO:0002309 FOODON:00003297 ! has exposure stimulus turkey sausage

[Term]
id: ECTO:0070075
name: exposure to poultry via ingestion
def: "An exposure to poultry (cooked) via ingestion." []
synonym: "poultry (cooked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03317344 ! has exposure stimulus poultry (cooked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03317344 ! has exposure stimulus poultry (cooked)

[Term]
id: ECTO:0070076
name: exposure to bacon (fried) via ingestion
def: "An exposure to bacon (fried) via ingestion." []
synonym: "bacon (fried) exposure via ingestion" EXACT []
is_a: ECTO:0070185 ! exposure to bacon (whole cut or parts) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310564 ! has exposure stimulus bacon (fried)
relationship: RO:0002309 FOODON:03310564 ! has exposure stimulus bacon (fried)

[Term]
id: ECTO:0070077
name: exposure to bacon (baked) via ingestion
def: "An exposure to bacon (baked) via ingestion." []
synonym: "bacon (baked) exposure via ingestion" EXACT []
is_a: ECTO:0070185 ! exposure to bacon (whole cut or parts) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311588 ! has exposure stimulus bacon (baked)
relationship: RO:0002309 FOODON:03311588 ! has exposure stimulus bacon (baked)

[Term]
id: ECTO:0070078
name: exposure to luncheon meat via ingestion
def: "An exposure to luncheon meat via ingestion." []
synonym: "luncheon meat exposure via ingestion" EXACT []
is_a: ECTO:0070084 ! exposure to processed meat food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310675 ! has exposure stimulus luncheon meat
relationship: RO:0002309 FOODON:03310675 ! has exposure stimulus luncheon meat

[Term]
id: ECTO:0070079
name: exposure to salami via ingestion
def: "An exposure to salami via ingestion." []
synonym: "salami exposure via ingestion" EXACT []
is_a: ECTO:0070078 ! exposure to luncheon meat via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03312067 ! has exposure stimulus salami
relationship: RO:0002309 FOODON:03312067 ! has exposure stimulus salami

[Term]
id: ECTO:0070080
name: exposure to bologna via ingestion
def: "An exposure to bologna via ingestion." []
synonym: "bologna exposure via ingestion" EXACT []
is_a: ECTO:0070084 ! exposure to processed meat food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03306503 ! has exposure stimulus bologna
relationship: RO:0002309 FOODON:03306503 ! has exposure stimulus bologna

[Term]
id: ECTO:0070081
name: exposure to beef sausage via ingestion
def: "An exposure to beef sausage via ingestion." []
synonym: "beef sausage exposure via ingestion" EXACT []
is_a: ECTO:0070078 ! exposure to luncheon meat via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002958 ! has exposure stimulus beef sausage
relationship: RO:0002309 FOODON:00002958 ! has exposure stimulus beef sausage

[Term]
id: ECTO:0070082
name: exposure to kielbasa via ingestion
def: "An exposure to Kielbasa via ingestion." []
synonym: "Kielbasa exposure via ingestion" EXACT []
is_a: ECTO:0070084 ! exposure to processed meat food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002728 ! has exposure stimulus Kielbasa
relationship: RO:0002309 FOODON:00002728 ! has exposure stimulus Kielbasa

[Term]
id: ECTO:0070083
name: exposure to meat (processed) via ingestion
def: "An exposure to meat (processed) via ingestion." []
synonym: "meat (processed) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310826 ! has exposure stimulus meat (processed)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310826 ! has exposure stimulus meat (processed)

[Term]
id: ECTO:0070084
name: exposure to processed meat food product via ingestion
def: "An exposure to processed meat food product via ingestion." []
synonym: "processed meat food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001010 ! has exposure stimulus processed meat food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001010 ! has exposure stimulus processed meat food product

[Term]
id: ECTO:0070085
name: exposure to ground beef via ingestion
def: "An exposure to ground beef (cooked) via ingestion." []
synonym: "ground beef (cooked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310753 ! has exposure stimulus ground beef (cooked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310753 ! has exposure stimulus ground beef (cooked)

[Term]
id: ECTO:0070086
name: exposure to beef hamburger (dish) via ingestion
def: "An exposure to beef hamburger (dish) via ingestion." []
synonym: "beef hamburger (dish) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002737 ! has exposure stimulus beef hamburger (dish)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002737 ! has exposure stimulus beef hamburger (dish)

[Term]
id: ECTO:0070087
name: exposure to beef (cooked) via ingestion
def: "An exposure to beef (cooked) via ingestion." []
synonym: "beef (cooked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03309738 ! has exposure stimulus beef (cooked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03309738 ! has exposure stimulus beef (cooked)

[Term]
id: ECTO:0070088
name: exposure to pork via ingestion
def: "An exposure to pork (cooked) via ingestion." []
synonym: "pork (cooked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311610 ! has exposure stimulus pork (cooked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03311610 ! has exposure stimulus pork (cooked)

[Term]
id: ECTO:0070089
name: exposure to lamb via ingestion
def: "An exposure to lamb (roasted) via ingestion." []
synonym: "lamb (roasted) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311664 ! has exposure stimulus lamb (roasted)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03311664 ! has exposure stimulus lamb (roasted)

[Term]
id: ECTO:0070090
name: exposure to ham (sliced, cooked) via ingestion
def: "An exposure to ham (sliced, cooked) via ingestion." []
synonym: "ham (sliced, cooked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311694 ! has exposure stimulus ham (sliced, cooked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03311694 ! has exposure stimulus ham (sliced, cooked)

[Term]
id: ECTO:0070091
name: exposure to canned tuna via ingestion
def: "An exposure to tuna (white, solid pack, canned in water) via ingestion." []
synonym: "tuna (white, solid pack, canned in water) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03309003 ! has exposure stimulus tuna (white, solid pack, canned in water)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03309003 ! has exposure stimulus tuna (white, solid pack, canned in water)

[Term]
id: ECTO:0070092
name: exposure to shrimp via ingestion
def: "An exposure to shrimp via ingestion." []
synonym: "shrimp exposure via ingestion" EXACT []
is_a: ECTO:0070188 ! exposure to shellfish via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411237 ! has exposure stimulus shrimp
relationship: RO:0002309 FOODON:03411237 ! has exposure stimulus shrimp

[Term]
id: ECTO:0070093
name: exposure to lobster via ingestion
def: "An exposure to lobster via ingestion." []
synonym: "lobster exposure via ingestion" EXACT []
is_a: ECTO:0070188 ! exposure to shellfish via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411505 ! has exposure stimulus lobster
relationship: RO:0002309 FOODON:03411505 ! has exposure stimulus lobster

[Term]
id: ECTO:0070094
name: exposure to scallops via ingestion
def: "An exposure to scallop via ingestion." []
synonym: "scallop exposure via ingestion" EXACT []
is_a: ECTO:0070188 ! exposure to shellfish via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:02020805 ! has exposure stimulus scallop
relationship: RO:0002309 FOODON:02020805 ! has exposure stimulus scallop

[Term]
id: ECTO:0070095
name: exposure to tuna steak via ingestion
def: "An exposure to tuna steak via ingestion." []
synonym: "tuna steak exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002987 ! has exposure stimulus tuna steak
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002987 ! has exposure stimulus tuna steak

[Term]
id: ECTO:0070096
name: exposure to mackerel via ingestion
def: "An exposure to mackerel via ingestion." []
synonym: "mackerel exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411043 ! has exposure stimulus mackerel
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03411043 ! has exposure stimulus mackerel

[Term]
id: ECTO:0070097
name: exposure to salmon via ingestion
def: "An exposure to salmon via ingestion." []
synonym: "salmon exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003473 ! has exposure stimulus salmon
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003473 ! has exposure stimulus salmon

[Term]
id: ECTO:0070098
name: exposure to sardine via ingestion
def: "An exposure to sardine via ingestion." []
synonym: "sardine exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411558 ! has exposure stimulus sardine
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03411558 ! has exposure stimulus sardine

[Term]
id: ECTO:0070099
name: exposure to bluefish via ingestion
def: "An exposure to bluefish food product via ingestion." []
synonym: "bluefish food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001659 ! has exposure stimulus bluefish food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001659 ! has exposure stimulus bluefish food product

[Term]
id: ECTO:0070100
name: exposure to swordfish via ingestion
def: "An exposure to swordfish food product via ingestion." []
synonym: "swordfish food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002307 ! has exposure stimulus swordfish food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002307 ! has exposure stimulus swordfish food product

[Term]
id: ECTO:0070101
name: exposure to cod via ingestion
def: "An exposure to cod via ingestion." []
synonym: "cod exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411423 ! has exposure stimulus cod
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03411423 ! has exposure stimulus cod

[Term]
id: ECTO:0070102
name: exposure to haddock (raw) via ingestion
def: "An exposure to haddock (raw) via ingestion." []
synonym: "haddock (raw) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03308024 ! has exposure stimulus haddock (raw)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03308024 ! has exposure stimulus haddock (raw)

[Term]
id: ECTO:0070103
name: exposure to halibut via ingestion
def: "An exposure to halibut via ingestion." []
synonym: "halibut exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411532 ! has exposure stimulus halibut
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03411532 ! has exposure stimulus halibut

[Term]
id: ECTO:0070104
name: exposure to cold cereal via ingestion
def: "An exposure to cereal (dry) via ingestion." []
synonym: "cereal (dry) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03316213 ! has exposure stimulus cereal (dry)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03316213 ! has exposure stimulus cereal (dry)

[Term]
id: ECTO:0070105
name: exposure to cooked oatmeal via ingestion
def: "An exposure to oatmeal (cooked) via ingestion." []
synonym: "oatmeal (cooked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310806 ! has exposure stimulus oatmeal (cooked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310806 ! has exposure stimulus oatmeal (cooked)

[Term]
id: ECTO:0070106
name: exposure to cooked oat bran via ingestion
def: "An exposure to oat bran via ingestion." []
synonym: "oat bran exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003774 ! has exposure stimulus oat bran
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003774 ! has exposure stimulus oat bran

[Term]
id: ECTO:0070107
name: exposure to cooked breakfast cereal via ingestion
def: "An exposure to breakfast cereal (cooked) via ingestion." []
synonym: "breakfast cereal (cooked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311540 ! has exposure stimulus breakfast cereal (cooked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03311540 ! has exposure stimulus breakfast cereal (cooked)

[Term]
id: ECTO:0070108
name: exposure to whole wheat crackers via ingestion
def: "An exposure to whole wheat cracker via ingestion." []
synonym: "whole wheat cracker exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302651 ! has exposure stimulus whole wheat cracker
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03302651 ! has exposure stimulus whole wheat cracker

[Term]
id: ECTO:0070109
name: exposure to crackers via ingestion
def: "An exposure to cracker via ingestion." []
synonym: "cracker exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002711 ! has exposure stimulus cracker
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002711 ! has exposure stimulus cracker

[Term]
id: ECTO:0070110
name: exposure to white bread via ingestion
def: "An exposure to white bread via ingestion." []
synonym: "white bread exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301055 ! has exposure stimulus white bread
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301055 ! has exposure stimulus white bread

[Term]
id: ECTO:0070111
name: exposure to pita bread via ingestion
def: "An exposure to pita bread via ingestion." []
synonym: "pita bread exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003060 ! has exposure stimulus pita bread
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003060 ! has exposure stimulus pita bread

[Term]
id: ECTO:0070112
name: exposure to rye bread via ingestion
def: "An exposure to rye bread (enriched) via ingestion." []
synonym: "rye bread (enriched) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305210 ! has exposure stimulus rye bread (enriched)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03305210 ! has exposure stimulus rye bread (enriched)

[Term]
id: ECTO:0070113
name: exposure to pumpernickel bread via ingestion
def: "An exposure to pumpernickel bread via ingestion." []
synonym: "pumpernickel bread exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302357 ! has exposure stimulus pumpernickel bread
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03302357 ! has exposure stimulus pumpernickel bread

[Term]
id: ECTO:0070114
name: exposure to whole wheat bread via ingestion
def: "An exposure to whole wheat bread via ingestion." []
synonym: "whole wheat bread exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301119 ! has exposure stimulus whole wheat bread
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301119 ! has exposure stimulus whole wheat bread

[Term]
id: ECTO:0070115
name: exposure to multigrain bread via ingestion
def: "An exposure to multigrain bread via ingestion." []
synonym: "multigrain bread exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302478 ! has exposure stimulus multigrain bread
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03302478 ! has exposure stimulus multigrain bread

[Term]
id: ECTO:0070116
name: exposure to bagel via ingestion
def: "An exposure to bagel via ingestion." []
synonym: "bagel exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03309554 ! has exposure stimulus bagel
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03309554 ! has exposure stimulus bagel

[Term]
id: ECTO:0070117
name: exposure to english muffin via ingestion
def: "An exposure to english muffin via ingestion." []
synonym: "english muffin exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305833 ! has exposure stimulus english muffin
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03305833 ! has exposure stimulus english muffin

[Term]
id: ECTO:0070118
name: exposure to bread roll via ingestion
def: "An exposure to wheat roll or bun via ingestion." []
synonym: "wheat roll or bun exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301931 ! has exposure stimulus wheat roll or bun
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301931 ! has exposure stimulus wheat roll or bun

[Term]
id: ECTO:0070119
name: exposure to muffin via ingestion
def: "An exposure to muffin via ingestion." []
synonym: "muffin exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03309530 ! has exposure stimulus muffin
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03309530 ! has exposure stimulus muffin

[Term]
id: ECTO:0070120
name: exposure to biscuit via ingestion
def: "An exposure to biscuit (quick bread) via ingestion." []
synonym: "biscuit (quick bread) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301884 ! has exposure stimulus biscuit (quick bread)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301884 ! has exposure stimulus biscuit (quick bread)

[Term]
id: ECTO:0070121
name: exposure to pancake via ingestion
def: "An exposure to pancake via ingestion." []
synonym: "pancake exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315258 ! has exposure stimulus pancake
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03315258 ! has exposure stimulus pancake

[Term]
id: ECTO:0070122
name: exposure to waffle via ingestion
def: "An exposure to waffle via ingestion." []
synonym: "waffle exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315259 ! has exposure stimulus waffle
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03315259 ! has exposure stimulus waffle

[Term]
id: ECTO:0070123
name: exposure to brown rice via ingestion
def: "An exposure to brown rice kernel via ingestion." []
synonym: "brown rice kernel exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003436 ! has exposure stimulus brown rice kernel
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003436 ! has exposure stimulus brown rice kernel

[Term]
id: ECTO:0070124
name: exposure to white rice via ingestion
def: "An exposure to white rice via ingestion." []
synonym: "white rice exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003787 ! has exposure stimulus white rice
relationship: RO:0002309 FOODON:00003787 ! has exposure stimulus white rice

[Term]
id: ECTO:0070125
name: exposure to pasta via ingestion
def: "An exposure to pasta via ingestion." []
synonym: "pasta exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03306347 ! has exposure stimulus pasta
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03306347 ! has exposure stimulus pasta

[Term]
id: ECTO:0070126
name: exposure to spaghetti noodle via ingestion
def: "An exposure to spaghetti macaroni (enriched) via ingestion." []
synonym: "spaghetti macaroni (enriched) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03304262 ! has exposure stimulus spaghetti macaroni (enriched)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03304262 ! has exposure stimulus spaghetti macaroni (enriched)

[Term]
id: ECTO:0070127
name: exposure to couscous via ingestion
def: "An exposure to couscous (dried) via ingestion." []
synonym: "couscous (dried) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303207 ! has exposure stimulus couscous (dried)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303207 ! has exposure stimulus couscous (dried)

[Term]
id: ECTO:0070128
name: exposure to tortilla via ingestion
def: "An exposure to tortilla via ingestion." []
synonym: "tortilla exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03307668 ! has exposure stimulus tortilla
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03307668 ! has exposure stimulus tortilla

[Term]
id: ECTO:0070129
name: exposure to french fries via ingestion
def: "An exposure to potato (french-fried) via ingestion." []
synonym: "potato (french-fried) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301959 ! has exposure stimulus potato (french-fried)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301959 ! has exposure stimulus potato (french-fried)

[Term]
id: ECTO:0070130
name: exposure to potato via ingestion
def: "An exposure to potato via ingestion." []
synonym: "potato exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315354 ! has exposure stimulus potato
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03315354 ! has exposure stimulus potato

[Term]
id: ECTO:0070131
name: exposure to pizza via ingestion
def: "An exposure to pizza food product via ingestion." []
synonym: "pizza food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310775 ! has exposure stimulus pizza food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310775 ! has exposure stimulus pizza food product

[Term]
id: ECTO:0070132
name: exposure to tea (decaffeinated) via ingestion
def: "An exposure to tea (decaffeinated) via ingestion." []
synonym: "tea (decaffeinated) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03312068 ! has exposure stimulus tea (decaffeinated)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03312068 ! has exposure stimulus tea (decaffeinated)

[Term]
id: ECTO:0070133
name: exposure to tea (steeped) via ingestion
def: "An exposure to tea (steeped) via ingestion." []
synonym: "tea (steeped) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310546 ! has exposure stimulus tea (steeped)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310546 ! has exposure stimulus tea (steeped)

[Term]
id: ECTO:0070134
name: exposure to coffee (liquid beverage) via ingestion
def: "An exposure to coffee (liquid drink) via ingestion." []
synonym: "coffee (liquid drink) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301036 ! has exposure stimulus coffee (liquid drink)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301036 ! has exposure stimulus coffee (liquid drink)

[Term]
id: ECTO:0070135
name: exposure to water via ingestion
def: "An exposure to spring water via ingestion." []
synonym: "spring water exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03307813 ! has exposure stimulus spring water
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03307813 ! has exposure stimulus spring water

[Term]
id: ECTO:0070136
name: exposure to sparkling water via ingestion
def: "An exposure to soda water via ingestion." []
synonym: "soda water exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302269 ! has exposure stimulus soda water
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03302269 ! has exposure stimulus soda water

[Term]
id: ECTO:0070137
name: exposure to milk chocolate via ingestion
def: "An exposure to milk chocolate via ingestion." []
synonym: "milk chocolate exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302806 ! has exposure stimulus milk chocolate
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03302806 ! has exposure stimulus milk chocolate

[Term]
id: ECTO:0070138
name: exposure to dark chocolate via ingestion
def: "An exposure to dark chocolate via ingestion." []
synonym: "dark chocolate exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303588 ! has exposure stimulus dark chocolate
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303588 ! has exposure stimulus dark chocolate

[Term]
id: ECTO:0070139
name: exposure to candy via ingestion
def: "An exposure to candy via ingestion." []
synonym: "candy exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301051 ! has exposure stimulus candy
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301051 ! has exposure stimulus candy

[Term]
id: ECTO:0070140
name: exposure to cookie via ingestion
def: "An exposure to cookie via ingestion." []
synonym: "cookie exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301585 ! has exposure stimulus cookie
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301585 ! has exposure stimulus cookie

[Term]
id: ECTO:0070141
name: exposure to brownie via ingestion
def: "An exposure to chocolate brownie via ingestion." []
synonym: "chocolate brownie exposure via ingestion" EXACT []
is_a: ECTO:0070144 ! exposure to cake via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002562 ! has exposure stimulus chocolate brownie
relationship: RO:0002309 FOODON:00002562 ! has exposure stimulus chocolate brownie

[Term]
id: ECTO:0070142
name: exposure to doughnut via ingestion
def: "An exposure to doughnut via ingestion." []
synonym: "doughnut exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301938 ! has exposure stimulus doughnut
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301938 ! has exposure stimulus doughnut

[Term]
id: ECTO:0070143
name: exposure to pastry via ingestion
def: "An exposure to pastry via ingestion." []
synonym: "pastry exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315272 ! has exposure stimulus pastry
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03315272 ! has exposure stimulus pastry

[Term]
id: ECTO:0070144
name: exposure to cake via ingestion
def: "An exposure to cake food product via ingestion." []
synonym: "cake food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001278 ! has exposure stimulus cake food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001278 ! has exposure stimulus cake food product

[Term]
id: ECTO:0070145
name: exposure to pie via ingestion
def: "An exposure to pie (baked) via ingestion." []
synonym: "pie (baked) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03317288 ! has exposure stimulus pie (baked)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03317288 ! has exposure stimulus pie (baked)

[Term]
id: ECTO:0070146
name: exposure to jam via ingestion
def: "An exposure to jam via ingestion." []
synonym: "jam exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03309973 ! has exposure stimulus jam
relationship: RO:0002309 FOODON:03309973 ! has exposure stimulus jam

[Term]
id: ECTO:0070147
name: exposure to jelly via ingestion
def: "An exposure to fruit jelly food product via ingestion." []
synonym: "fruit jelly food product exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001888 ! has exposure stimulus fruit jelly food product
relationship: RO:0002309 FOODON:00001888 ! has exposure stimulus fruit jelly food product

[Term]
id: ECTO:0070148
name: exposure to preserve via ingestion
def: "An exposure to fruit preserves via ingestion." []
synonym: "fruit preserves exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305304 ! has exposure stimulus fruit preserves
relationship: RO:0002309 FOODON:03305304 ! has exposure stimulus fruit preserves

[Term]
id: ECTO:0070149
name: exposure to honey via ingestion
def: "An exposure to honey food product via ingestion." []
synonym: "honey food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001178 ! has exposure stimulus honey food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001178 ! has exposure stimulus honey food product

[Term]
id: ECTO:0070150
name: exposure to syrup via ingestion
def: "An exposure to syrup via ingestion." []
synonym: "syrup exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303225 ! has exposure stimulus syrup
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303225 ! has exposure stimulus syrup

[Term]
id: ECTO:0070151
name: exposure to peanut butter via ingestion
def: "An exposure to peanut butter via ingestion." []
synonym: "peanut butter exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03306867 ! has exposure stimulus peanut butter
relationship: RO:0002309 FOODON:03306867 ! has exposure stimulus peanut butter

[Term]
id: ECTO:0070152
name: exposure to potato chips via ingestion
def: "An exposure to potato chip via ingestion." []
synonym: "potato chip exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301833 ! has exposure stimulus potato chip
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301833 ! has exposure stimulus potato chip

[Term]
id: ECTO:0070153
name: exposure to pretzels via ingestion
def: "An exposure to pretzel via ingestion." []
synonym: "pretzel exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303929 ! has exposure stimulus pretzel
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303929 ! has exposure stimulus pretzel

[Term]
id: ECTO:0070154
name: exposure to peanut via ingestion
def: "An exposure to peanut via ingestion." []
synonym: "peanut exposure via ingestion" EXACT []
is_a: ECTO:0070183 ! exposure to legume food product via ingestion
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003206 ! has exposure stimulus peanut
relationship: RO:0002309 FOODON:00003206 ! has exposure stimulus peanut

[Term]
id: ECTO:0070155
name: exposure to walnuts via ingestion
def: "An exposure to walnut (raw) via ingestion." []
synonym: "walnut (raw) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315233 ! has exposure stimulus walnut (raw)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03315233 ! has exposure stimulus walnut (raw)

[Term]
id: ECTO:0070156
name: exposure to nuts via ingestion
def: "An exposure to nut (whole or pieces) via ingestion." []
synonym: "nut (whole or pieces) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03306632 ! has exposure stimulus nut (whole or pieces)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03306632 ! has exposure stimulus nut (whole or pieces)

[Term]
id: ECTO:0070157
name: exposure to olive oil (extra virgin) via ingestion
def: "An exposure to olive oil (extra-virgin) via ingestion." []
synonym: "olive oil (extra-virgin) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002808 ! has exposure stimulus olive oil (extra-virgin)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002808 ! has exposure stimulus olive oil (extra-virgin)

[Term]
id: ECTO:0070158
name: exposure to mayonnaise via ingestion
def: "An exposure to mayonnaise via ingestion." []
synonym: "mayonnaise exposure via ingestion" EXACT []
is_a: ECTO:0070159 ! exposure to salad dressing via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301440 ! has exposure stimulus mayonnaise
relationship: RO:0002309 FOODON:03301440 ! has exposure stimulus mayonnaise

[Term]
id: ECTO:0070159
name: exposure to salad dressing via ingestion
def: "An exposure to salad dressing via ingestion." []
synonym: "salad dressing exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001290 ! has exposure stimulus salad dressing
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001290 ! has exposure stimulus salad dressing

[Term]
id: ECTO:0070160
name: exposure to aspartame via ingestion
def: "An exposure to aspartame via ingestion." []
synonym: "aspartame exposure via ingestion" EXACT []
is_a: ECTO:0900059 ! exposure to peptide via ingestion
is_a: ECTO:9000578 ! exposure to aspartame
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:2877 ! has exposure stimulus aspartame

[Term]
id: ECTO:0070161
name: exposure to sugar (granulated) via ingestion
def: "An exposure to sugar (granulated) via ingestion." []
synonym: "sugar (granulated) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301073 ! has exposure stimulus sugar (granulated)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301073 ! has exposure stimulus sugar (granulated)

[Term]
id: ECTO:0070162
name: exposure to black cohosh supplement via ingestion
def: "An exposure to black cohosh supplement via ingestion." []
synonym: "black cohosh supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600000 ! has exposure stimulus black cohosh supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600000 ! has exposure stimulus black cohosh supplement

[Term]
id: ECTO:0070163
name: exposure to coenzyme Q10 supplement via ingestion
def: "An exposure to coenzyme Q10 supplement via ingestion." []
synonym: "coenzyme Q10 supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600001 ! has exposure stimulus coenzyme Q10 supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600001 ! has exposure stimulus coenzyme Q10 supplement

[Term]
id: ECTO:0070164
name: exposure to fish oil supplement via ingestion
def: "An exposure to fish oil supplement via ingestion." []
synonym: "fish oil supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600002 ! has exposure stimulus fish oil supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600002 ! has exposure stimulus fish oil supplement

[Term]
id: ECTO:0070165
name: exposure to flaxseed oil supplement via ingestion
def: "An exposure to flaxseed oil supplement via ingestion." []
synonym: "flaxseed oil supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600003 ! has exposure stimulus flaxseed oil supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600003 ! has exposure stimulus flaxseed oil supplement

[Term]
id: ECTO:0070166
name: exposure to ginkgo biloba supplement via ingestion
def: "An exposure to ginkgo biloba supplement via ingestion." []
synonym: "ginkgo biloba supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600004 ! has exposure stimulus ginkgo biloba supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600004 ! has exposure stimulus ginkgo biloba supplement

[Term]
id: ECTO:0070167
name: exposure to ginseng supplement via ingestion
def: "An exposure to ginseng supplement via ingestion." []
synonym: "ginseng supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600005 ! has exposure stimulus ginseng supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600005 ! has exposure stimulus ginseng supplement

[Term]
id: ECTO:0070168
name: exposure to glucosamine supplement via ingestion
def: "An exposure to glucosamine supplement via ingestion." []
synonym: "glucosamine supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600006 ! has exposure stimulus glucosamine supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600006 ! has exposure stimulus glucosamine supplement

[Term]
id: ECTO:0070169
name: exposure to melatonin supplement via ingestion
def: "An exposure to melatonin supplement via ingestion." []
synonym: "melatonin supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600007 ! has exposure stimulus melatonin supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600007 ! has exposure stimulus melatonin supplement

[Term]
id: ECTO:0070170
name: exposure to milk thistle supplement via ingestion
def: "An exposure to milk thistle supplement via ingestion." []
synonym: "milk thistle supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600008 ! has exposure stimulus milk thistle supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600008 ! has exposure stimulus milk thistle supplement

[Term]
id: ECTO:0070171
name: exposure to omega-3- fatty acid supplement via ingestion
def: "An exposure to omega-3- fatty acid supplement via ingestion." []
synonym: "omega-3- fatty acid supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600009 ! has exposure stimulus omega-3- fatty acid supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600009 ! has exposure stimulus omega-3- fatty acid supplement

[Term]
id: ECTO:0070172
name: exposure to red yeast rice supplement via ingestion
def: "An exposure to red yeast rice supplement via ingestion." []
synonym: "red yeast rice supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600010 ! has exposure stimulus red yeast rice supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600010 ! has exposure stimulus red yeast rice supplement

[Term]
id: ECTO:0070173
name: exposure to resveratrol supplement via ingestion
def: "An exposure to resveratrol supplement via ingestion." []
synonym: "resveratrol supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600011 ! has exposure stimulus resveratrol supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600011 ! has exposure stimulus resveratrol supplement

[Term]
id: ECTO:0070174
name: exposure to St. John's wort supplement via ingestion
def: "An exposure to St. John's wort supplement via ingestion." []
synonym: "St. John's wort supplement exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03600012 ! has exposure stimulus St. John's wort supplement
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03600012 ! has exposure stimulus St. John's wort supplement

[Term]
id: ECTO:0070175
name: exposure to butter (unsalted) via ingestion
def: "An exposure to butter (unsalted) via ingestion." []
synonym: "butter (unsalted) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301777 ! has exposure stimulus butter (unsalted)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301777 ! has exposure stimulus butter (unsalted)

[Term]
id: ECTO:0070176
name: exposure to butter (salted) via ingestion
def: "An exposure to butter (salted) via ingestion." []
synonym: "butter (salted) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302643 ! has exposure stimulus butter (salted)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03302643 ! has exposure stimulus butter (salted)

[Term]
id: ECTO:0070177
name: exposure to peanut butter (smooth) via ingestion
def: "An exposure to peanut butter (creamy) via ingestion." []
synonym: "peanut butter (creamy) exposure via ingestion" EXACT []
is_a: ECTO:0070151 ! exposure to peanut butter via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03306903 ! has exposure stimulus peanut butter (creamy)
relationship: RO:0002309 FOODON:03306903 ! has exposure stimulus peanut butter (creamy)

[Term]
id: ECTO:0070178
name: exposure to Williams pear via ingestion
def: "An exposure to Williams pear via ingestion." []
synonym: "Williams pear exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003575 ! has exposure stimulus Williams pear
relationship: RO:0002309 FOODON:00003575 ! has exposure stimulus Williams pear

[Term]
id: ECTO:0070179
name: exposure to red onion via ingestion
def: "An exposure to red onion (raw) via ingestion." []
synonym: "red onion (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070056 ! exposure to onion via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003515 ! has exposure stimulus red onion (raw)
relationship: RO:0002309 FOODON:00003515 ! has exposure stimulus red onion (raw)

[Term]
id: ECTO:0070180
name: exposure to white onion via ingestion
def: "An exposure to white onion (raw) via ingestion." []
synonym: "white onion (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070056 ! exposure to onion via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003349 ! has exposure stimulus white onion (raw)
relationship: RO:0002309 FOODON:00003349 ! has exposure stimulus white onion (raw)

[Term]
id: ECTO:0070181
name: exposure to yellow onion via ingestion
def: "An exposure to yellow onion (raw) via ingestion." []
synonym: "yellow onion (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070056 ! exposure to onion via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311276 ! has exposure stimulus yellow onion (raw)
relationship: RO:0002309 FOODON:03311276 ! has exposure stimulus yellow onion (raw)

[Term]
id: ECTO:0070182
name: exposure to stone fruit via ingestion
def: "An exposure to stone fruit food product via ingestion." []
synonym: "stone fruit food product exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002277 ! has exposure stimulus stone fruit food product
relationship: RO:0002309 FOODON:00002277 ! has exposure stimulus stone fruit food product

[Term]
id: ECTO:0070183
name: exposure to legume food product via ingestion
def: "An exposure to legume food product via ingestion." []
synonym: "legume food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001264 ! has exposure stimulus legume food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001264 ! has exposure stimulus legume food product

[Term]
id: ECTO:0070184
name: exposure to plant leaf vegetable food product via ingestion
def: "An exposure to plant leaf food product via ingestion." []
synonym: "plant leaf food product exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002143 ! has exposure stimulus plant leaf food product
relationship: RO:0002309 FOODON:00002143 ! has exposure stimulus plant leaf food product

[Term]
id: ECTO:0070185
name: exposure to bacon (whole cut or parts) via ingestion
def: "An exposure to bacon (whole cut or pieces) via ingestion." []
synonym: "bacon (whole cut or pieces) exposure via ingestion" EXACT []
is_a: ECTO:0070084 ! exposure to processed meat food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03317331 ! has exposure stimulus bacon (whole cut or pieces)
relationship: RO:0002309 FOODON:03317331 ! has exposure stimulus bacon (whole cut or pieces)

[Term]
id: ECTO:0070186
name: exposure to poultry (processed) via ingestion
def: "An exposure to poultry (processed) via ingestion." []
synonym: "poultry (processed) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310828 ! has exposure stimulus poultry (processed)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03310828 ! has exposure stimulus poultry (processed)

[Term]
id: ECTO:0070187
name: exposure to red meat (raw) via ingestion
def: "An exposure to red meat (raw) via ingestion." []
synonym: "red meat (raw) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301297 ! has exposure stimulus red meat (raw)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301297 ! has exposure stimulus red meat (raw)

[Term]
id: ECTO:0070188
name: exposure to shellfish via ingestion
def: "An exposure to shellfish species via ingestion." []
synonym: "shellfish species exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411433 ! has exposure stimulus shellfish species
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03411433 ! has exposure stimulus shellfish species

[Term]
id: ECTO:0070189
name: exposure to whitefish via ingestion
def: "An exposure to whitefish (fisheries term) via ingestion." []
synonym: "whitefish (fisheries term) exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003281 ! has exposure stimulus whitefish (fisheries term)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003281 ! has exposure stimulus whitefish (fisheries term)

[Term]
id: ECTO:0070190
name: exposure to spinach (cooked) via ingestion
def: "An exposure to spinach (cooked) via ingestion." []
synonym: "spinach (cooked) exposure via ingestion" EXACT []
is_a: ECTO:0070184 ! exposure to plant leaf vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003908 ! has exposure stimulus spinach (cooked)
relationship: RO:0002309 FOODON:00003908 ! has exposure stimulus spinach (cooked)

[Term]
id: ECTO:0070191
name: exposure to whole grain bread via ingestion
def: "An exposure to whole grain bread via ingestion." []
synonym: "whole grain bread exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003923 ! has exposure stimulus whole grain bread
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003923 ! has exposure stimulus whole grain bread

[Term]
id: ECTO:0070192
name: exposure to whole oat bread via ingestion
def: "An exposure to whole oat bread via ingestion." []
synonym: "whole oat bread exposure via ingestion" EXACT []
is_a: ECTO:0070191 ! exposure to whole grain bread via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003938 ! has exposure stimulus whole oat bread
relationship: RO:0002309 FOODON:00003938 ! has exposure stimulus whole oat bread

[Term]
id: ECTO:0070193
name: exposure to soft drink (diet, caffeinated) via ingestion
def: "An exposure to diet soft drink (caffeinated) via ingestion." []
synonym: "diet soft drink (caffeinated) exposure via ingestion" EXACT []
is_a: ECTO:0070194 ! exposure to soft drink (caffeinated) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003939 ! has exposure stimulus diet soft drink (caffeinated)
relationship: RO:0002309 FOODON:00003939 ! has exposure stimulus diet soft drink (caffeinated)

[Term]
id: ECTO:0070194
name: exposure to soft drink (caffeinated) via ingestion
def: "An exposure to soft drink (caffeinated) via ingestion." []
synonym: "soft drink (caffeinated) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003940 ! has exposure stimulus soft drink (caffeinated)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003940 ! has exposure stimulus soft drink (caffeinated)

[Term]
id: ECTO:0070195
name: exposure to tea (liquid, decaffeinated) via ingestion
def: "An exposure to tea (liquid, decafeinated) via ingestion." []
synonym: "tea (liquid, decafeinated) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003941 ! has exposure stimulus tea (liquid, decafeinated)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003941 ! has exposure stimulus tea (liquid, decafeinated)

[Term]
id: ECTO:0070196
name: exposure to tea (liquid, caffeinated) via ingestion
def: "An exposure to tea (liquid, caffeinated) via ingestion." []
synonym: "tea (liquid, caffeinated) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003942 ! has exposure stimulus tea (liquid, caffeinated)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003942 ! has exposure stimulus tea (liquid, caffeinated)

[Term]
id: ECTO:0070197
name: exposure to coffee (liquid, decaffeinated) via ingestion
def: "An exposure to coffee (liquid, decafeinated) via ingestion." []
synonym: "coffee (liquid, decafeinated) exposure via ingestion" EXACT []
is_a: ECTO:0070134 ! exposure to coffee (liquid beverage) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003943 ! has exposure stimulus coffee (liquid, decafeinated)
relationship: RO:0002309 FOODON:00003943 ! has exposure stimulus coffee (liquid, decafeinated)

[Term]
id: ECTO:0070198
name: exposure to dairy-based coffee drink via ingestion
def: "An exposure to dairy-based coffee drink via ingestion." []
synonym: "dairy-based coffee drink exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003944 ! has exposure stimulus dairy-based coffee drink
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003944 ! has exposure stimulus dairy-based coffee drink

[Term]
id: ECTO:0070199
name: exposure to cow milk cheese (nonfat) via ingestion
def: "An exposure to cow milk cheese (nonfat) via ingestion." []
synonym: "cow milk cheese (nonfat) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003945 ! has exposure stimulus cow milk cheese (nonfat)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003945 ! has exposure stimulus cow milk cheese (nonfat)

[Term]
id: ECTO:0070200
name: exposure to winter squash (whole) via ingestion
def: "An exposure to winter squash via ingestion." []
synonym: "winter squash exposure via ingestion" EXACT []
is_a: ECTO:0070051 ! exposure to squash via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003946 ! has exposure stimulus winter squash
relationship: RO:0002309 FOODON:00003946 ! has exposure stimulus winter squash

[Term]
id: ECTO:0070201
name: exposure to sucralose-based sweetener via ingestion
def: "An exposure to sucralose-based sweetener via ingestion." []
synonym: "sucralose-based sweetener exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003947 ! has exposure stimulus sucralose-based sweetener
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003947 ! has exposure stimulus sucralose-based sweetener

[Term]
id: ECTO:0070202
name: exposure to aspartame-based sweetener via ingestion
def: "An exposure to aspartame-based sweetener via ingestion." []
synonym: "aspartame-based sweetener exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003948 ! has exposure stimulus aspartame-based sweetener
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003948 ! has exposure stimulus aspartame-based sweetener

[Term]
id: ECTO:0070203
name: exposure to saccharin-based sweetener via ingestion
def: "An exposure to saccharin-based sweetener via ingestion." []
synonym: "saccharin-based sweetener exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003949 ! has exposure stimulus saccharin-based sweetener
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003949 ! has exposure stimulus saccharin-based sweetener

[Term]
id: ECTO:0070204
name: exposure to cow milk (liquid) via ingestion
def: "An exposure to cow milk (liquid) via ingestion." []
synonym: "cow milk (liquid) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03302116 ! has exposure stimulus cow milk (liquid)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03302116 ! has exposure stimulus cow milk (liquid)

[Term]
id: ECTO:0070205
name: exposure to high mercury food material via ingestion
def: "An exposure to high mercury food material via ingestion." []
synonym: "high mercury food material exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00004101 ! has exposure stimulus high mercury food material
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00004101 ! has exposure stimulus high mercury food material

[Term]
id: ECTO:0070206
name: exposure to rice milk via ingestion
def: "An exposure to rice milk beverage via ingestion." []
synonym: "rice milk beverage exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311386 ! has exposure stimulus rice milk beverage
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03311386 ! has exposure stimulus rice milk beverage

[Term]
id: ECTO:0070207
name: exposure to coconut milk via ingestion
def: "An exposure to coconut milk via ingestion." []
synonym: "coconut milk exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303084 ! has exposure stimulus coconut milk
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303084 ! has exposure stimulus coconut milk

[Term]
id: ECTO:0070208
name: exposure to cashew milk via ingestion
def: "An exposure to cashew milk via ingestion." []
synonym: "cashew milk exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003866 ! has exposure stimulus cashew milk
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00003866 ! has exposure stimulus cashew milk

[Term]
id: ECTO:0070209
name: exposure to dark fish flesh via ingestion
def: "An exposure to dark fish flesh via ingestion." []
synonym: "dark fish flesh exposure via ingestion" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03530058 ! has exposure stimulus dark fish flesh
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03530058 ! has exposure stimulus dark fish flesh

[Term]
id: ECTO:0070210
name: exposure to multivitamin preparation via ingestion
def: "An exposure to multivitamin preparation via ingestion." []
synonym: "multivitamin preparation exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315171 ! has exposure stimulus multivitamin preparation
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03315171 ! has exposure stimulus multivitamin preparation

[Term]
id: ECTO:0070211
name: exposure to mineral water via ingestion
def: "An exposure to mineral water via ingestion." []
synonym: "mineral water exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301328 ! has exposure stimulus mineral water
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301328 ! has exposure stimulus mineral water

[Term]
id: ECTO:0070212
name: exposure to infant formula based on isolated amino acids and/or protein hydrolysates via ingestion
def: "An exposure to infant formula based on isolated amino acids and/or protein hydrolysates via ingestion." []
synonym: "infant formula based on isolated amino acids and/or protein hydrolysates exposure via ingestion" EXACT []
is_a: ECTO:0070225 ! exposure to infant formula via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315760 ! has exposure stimulus infant formula based on isolated amino acids and/or protein hydrolysates
relationship: RO:0002309 FOODON:03315760 ! has exposure stimulus infant formula based on isolated amino acids and/or protein hydrolysates

[Term]
id: ECTO:0070213
name: exposure to blue mussel via ingestion
def: "An exposure to blue mussel via ingestion." []
synonym: "blue mussel exposure via ingestion" EXACT []
is_a: ECTO:0070188 ! exposure to shellfish via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03412875 ! has exposure stimulus blue mussel
relationship: RO:0002309 FOODON:03412875 ! has exposure stimulus blue mussel

[Term]
id: ECTO:0070214
name: exposure to citrus fruit (raw) via ingestion
def: "An exposure to citrus fruit (raw) via ingestion." []
synonym: "citrus fruit (raw) exposure via ingestion" EXACT []
is_a: ECTO:0070220 ! exposure to fruit food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301337 ! has exposure stimulus citrus fruit (raw)
relationship: RO:0002309 FOODON:03301337 ! has exposure stimulus citrus fruit (raw)

[Term]
id: ECTO:0070215
name: exposure to feedstuff (food for agricultural animals) via ingestion
def: "An exposure to feedstuff (food for agricultural animals) via ingestion." []
synonym: "feedstuff (food for agricultural animals) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00004172 ! has exposure stimulus feedstuff (food for agricultural animals)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00004172 ! has exposure stimulus feedstuff (food for agricultural animals)

[Term]
id: ECTO:0070216
name: exposure to watercress via ingestion
def: "An exposure to watercress via ingestion." []
synonym: "watercress exposure via ingestion" EXACT []
is_a: ECTO:0070184 ! exposure to plant leaf vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003064 ! has exposure stimulus watercress
relationship: RO:0002309 FOODON:00003064 ! has exposure stimulus watercress

[Term]
id: ECTO:0070217
name: exposure to high fiber food via ingestion
def: "An exposure to high fiber food via ingestion." []
synonym: "high fiber food exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03510048 ! has exposure stimulus high fiber food
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03510048 ! has exposure stimulus high fiber food

[Term]
id: ECTO:0070218
name: exposure to sodium chloride food material via ingestion
def: "An exposure to sodium chloride food material via ingestion." []
synonym: "sodium chloride food material exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002250 ! has exposure stimulus sodium chloride food material
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002250 ! has exposure stimulus sodium chloride food material

[Term]
id: ECTO:0070219
name: exposure to brewers grains (exhausted) via ingestion
def: "An exposure to brewers grains (exhausted) via ingestion." []
synonym: "brewers grains (exhausted) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03305501 ! has exposure stimulus brewers grains (exhausted)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03305501 ! has exposure stimulus brewers grains (exhausted)

[Term]
id: ECTO:0070220
name: exposure to fruit food product via ingestion
def: "An exposure to fruit food product via ingestion." []
synonym: "fruit food product exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315615 ! has exposure stimulus fruit food product
relationship: RO:0002309 FOODON:03315615 ! has exposure stimulus fruit food product

[Term]
id: ECTO:0070221
name: exposure to fruit-flavored beverage (carbonated) via ingestion
def: "An exposure to fruit-flavored beverage (carbonated) via ingestion." []
synonym: "fruit-flavored beverage (carbonated) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301869 ! has exposure stimulus fruit-flavored beverage (carbonated)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301869 ! has exposure stimulus fruit-flavored beverage (carbonated)

[Term]
id: ECTO:0070222
name: exposure to starch (hydrolyzed, solid) via ingestion
def: "An exposure to starch (hydrolyzed, solid) via ingestion." []
synonym: "starch (hydrolyzed, solid) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03317669 ! has exposure stimulus starch (hydrolyzed, solid)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03317669 ! has exposure stimulus starch (hydrolyzed, solid)

[Term]
id: ECTO:0070223
name: exposure to high fibre food material via ingestion
def: "An exposure to high fibre food material via ingestion." []
synonym: "high fibre food material exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00004103 ! has exposure stimulus high fibre food material
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00004103 ! has exposure stimulus high fibre food material

[Term]
id: ECTO:0070224
name: exposure to human milk (raw) via ingestion
def: "An exposure to human milk (raw) via ingestion." []
synonym: "human milk (raw) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303918 ! has exposure stimulus human milk (raw)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303918 ! has exposure stimulus human milk (raw)

[Term]
id: ECTO:0070225
name: exposure to infant formula via ingestion
def: "An exposure to infant formula via ingestion." []
synonym: "infant formula exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03303130 ! has exposure stimulus infant formula
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03303130 ! has exposure stimulus infant formula

[Term]
id: ECTO:0070226
name: exposure to infant formula (milk-based) via ingestion
def: "An exposure to infant formula (milk-based) via ingestion." []
synonym: "infant formula (milk-based) exposure via ingestion" EXACT []
is_a: ECTO:0070225 ! exposure to infant formula via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03311523 ! has exposure stimulus infant formula (milk-based)
relationship: RO:0002309 FOODON:03311523 ! has exposure stimulus infant formula (milk-based)

[Term]
id: ECTO:0070227
name: exposure to liquid food (prepared, ready for consumption) via ingestion
def: "An exposure to liquid food (prepared, ready for consumption) via ingestion." []
synonym: "liquid food (prepared, ready for consumption) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03317133 ! has exposure stimulus liquid food (prepared, ready for consumption)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03317133 ! has exposure stimulus liquid food (prepared, ready for consumption)

[Term]
id: ECTO:0070228
name: exposure to red wine via ingestion
def: "An exposure to red wine via ingestion." []
synonym: "red wine exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03310272 ! has exposure stimulus red wine
relationship: RO:0002309 FOODON:03310272 ! has exposure stimulus red wine

[Term]
id: ECTO:0070229
name: exposure to noodle via ingestion
def: "An exposure to noodle via ingestion." []
synonym: "noodle exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03306944 ! has exposure stimulus noodle
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03306944 ! has exposure stimulus noodle

[Term]
id: ECTO:0070230
name: exposure to rapeseed food product via ingestion
def: "An exposure to rapeseed food product via ingestion." []
synonym: "rapeseed food product exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002187 ! has exposure stimulus rapeseed food product
relationship: RO:0002309 FOODON:00002187 ! has exposure stimulus rapeseed food product

[Term]
id: ECTO:0070232
name: exposure to vegetable food product via ingestion
def: "An exposure to vegetable food product via ingestion." []
synonym: "vegetable food product exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001261 ! has exposure stimulus vegetable food product
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001261 ! has exposure stimulus vegetable food product

[Term]
id: ECTO:0070233
name: exposure to vegetable or vegetable product (us cfr) via ingestion
def: "An exposure to vegetable or vegetable product (us cfr) via ingestion." []
synonym: "vegetable or vegetable product (us cfr) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03400152 ! has exposure stimulus vegetable or vegetable product (us cfr)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03400152 ! has exposure stimulus vegetable or vegetable product (us cfr)

[Term]
id: ECTO:0070234
name: exposure to whey protein isolate via ingestion
def: "An exposure to whey protein isolate via ingestion." []
synonym: "whey protein isolate exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00005524 ! has exposure stimulus whey protein isolate
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00005524 ! has exposure stimulus whey protein isolate

[Term]
id: ECTO:0070235
name: exposure to apple juice (from cores and peels) via ingestion
def: "An exposure to apple juice (from cores and peels) via ingestion." []
synonym: "apple juice (from cores and peels) exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03304795 ! has exposure stimulus apple juice (from cores and peels)
relationship: RO:0002309 FOODON:03304795 ! has exposure stimulus apple juice (from cores and peels)

[Term]
id: ECTO:0070236
name: exposure to carbohydrate reduced food via ingestion
def: "An exposure to carbohydrate reduced food via ingestion." []
synonym: "carbohydrate reduced food exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03315824 ! has exposure stimulus carbohydrate reduced food
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03315824 ! has exposure stimulus carbohydrate reduced food

[Term]
id: ECTO:0070237
name: exposure to grain or starch product (us cfr) via ingestion
def: "An exposure to grain or starch product (us cfr) via ingestion." []
synonym: "grain or starch product (us cfr) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03400125 ! has exposure stimulus grain or starch product (us cfr)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03400125 ! has exposure stimulus grain or starch product (us cfr)

[Term]
id: ECTO:0070239
name: exposure to seaweed via ingestion
def: "An exposure to seaweed via ingestion." []
synonym: "seaweed exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03412266 ! has exposure stimulus seaweed
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03412266 ! has exposure stimulus seaweed

[Term]
id: ECTO:0070240
name: exposure to spirulina via ingestion
def: "An exposure to spirulina via ingestion." []
synonym: "spirulina exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03412039 ! has exposure stimulus spirulina
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03412039 ! has exposure stimulus spirulina

[Term]
id: ECTO:0070241
name: exposure to wheat germ via ingestion
def: "An exposure to wheat germ via ingestion." []
synonym: "wheat germ exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301595 ! has exposure stimulus wheat germ
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03301595 ! has exposure stimulus wheat germ

[Term]
id: ECTO:0070242
name: exposure to blood meal via ingestion
def: "An exposure to blood meal via ingestion." []
synonym: "blood meal exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001564 ! has exposure stimulus blood meal
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00001564 ! has exposure stimulus blood meal

[Term]
id: ECTO:0070243
name: exposure to celery food product via ingestion
def: "An exposure to celery food product via ingestion." []
synonym: "celery food product exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00001704 ! has exposure stimulus celery food product
relationship: RO:0002309 FOODON:00001704 ! has exposure stimulus celery food product

[Term]
id: ECTO:0070244
name: exposure to crustacean (whole or flesh piece) via ingestion
def: "An exposure to crustacean (whole or flesh piece) via ingestion." []
synonym: "crustacean (whole or flesh piece) exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03317448 ! has exposure stimulus crustacean (whole or flesh piece)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03317448 ! has exposure stimulus crustacean (whole or flesh piece)

[Term]
id: ECTO:0070245
name: exposure to dietary supplement, vitamin(s) and fatty acids via ingestion
def: "An exposure to dietary supplement, vitamin(s) and fatty acids via ingestion." []
synonym: "dietary supplement, vitamin(s) and fatty acids exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03401324 ! has exposure stimulus dietary supplement, vitamin(s) and fatty acids
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03401324 ! has exposure stimulus dietary supplement, vitamin(s) and fatty acids

[Term]
id: ECTO:0070246
name: exposure to broad bean via ingestion
def: "An exposure to broad bean via ingestion." []
synonym: "broad bean exposure via ingestion" EXACT []
is_a: ECTO:0070040 ! exposure to bean via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301227 ! has exposure stimulus broad bean
relationship: RO:0002309 FOODON:03301227 ! has exposure stimulus broad bean

[Term]
id: ECTO:0070247
name: exposure to fat content 50-80%, > 25% pufa via ingestion
def: "An exposure to fat content 50-80%, > 25% pufa via ingestion." []
synonym: "fat content 50-80%, > 25% pufa exposure via ingestion" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03530201 ! has exposure stimulus fat content 50-80%, > 25% pufa
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03530201 ! has exposure stimulus fat content 50-80%, > 25% pufa

[Term]
id: ECTO:0070248
name: exposure to high fructose food material via ingestion
def: "An exposure to high fructose food material via ingestion." []
synonym: "high fructose food material exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00004102 ! has exposure stimulus high fructose food material
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00004102 ! has exposure stimulus high fructose food material

[Term]
id: ECTO:0070249
name: exposure to insect via ingestion
def: "An exposure to insect via ingestion." []
synonym: "insect exposure via ingestion" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03411220 ! has exposure stimulus insect
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03411220 ! has exposure stimulus insect

[Term]
id: ECTO:0070250
name: exposure to milk fat via ingestion
def: "An exposure to milk fat via ingestion." []
synonym: "milk fat exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00002681 ! has exposure stimulus milk fat
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:00002681 ! has exposure stimulus milk fat

[Term]
id: ECTO:0070251
name: exposure to fat content 46-60% via ingestion
def: "An exposure to fat content 46-60% via ingestion." []
synonym: "fat content 46-60% exposure via ingestion" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03530195 ! has exposure stimulus fat content 46-60%
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03530195 ! has exposure stimulus fat content 46-60%

[Term]
id: ECTO:0070252
name: exposure to mammalian milk protein via ingestion
def: "An exposure to mammalian milk protein via ingestion." []
synonym: "mammalian milk protein exposure via ingestion" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03460748 ! has exposure stimulus mammalian milk protein
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03460748 ! has exposure stimulus mammalian milk protein

[Term]
id: ECTO:0070253
name: exposure to pumpkin via ingestion
def: "An exposure to pumpkin via ingestion." []
synonym: "pumpkin exposure via ingestion" EXACT []
is_a: ECTO:0070200 ! exposure to winter squash (whole) via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:00003486 ! has exposure stimulus pumpkin
relationship: RO:0002309 FOODON:00003486 ! has exposure stimulus pumpkin

[Term]
id: ECTO:0070254
name: exposure to tomato powder via ingestion
def: "An exposure to tomato powder via ingestion." []
synonym: "tomato powder exposure via ingestion" EXACT []
is_a: ECTO:0070232 ! exposure to vegetable food product via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03301459 ! has exposure stimulus tomato powder
relationship: RO:0002309 FOODON:03301459 ! has exposure stimulus tomato powder

[Term]
id: ECTO:0080000
name: exposure to arsenic in water via ingestion
def: "An exposure to arsenic atom mixed in liquid water via ingestion route." []
synonym: "arsenic atom exposure in liquid water via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002355 ! exposure to arsenic atom
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27563 ! has exposure stimulus arsenic atom
intersection_of: RO:0016004 ENVO:00002006 ! has exposure medium liquid water
relationship: RO:0016004 ENVO:00002006 ! has exposure medium liquid water

[Term]
id: ECTO:0080001
name: exposure to polycyclic hydrocarbon in air via inhalation
def: "An exposure to polycyclic hydrocarbon mixed in air via inhalation route." []
synonym: "polycyclic hydrocarbon exposure in air via inhalation route" EXACT []
is_a: ECTO:9002148 ! exposure to polycyclic hydrocarbon
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:33666 ! has exposure stimulus polycyclic hydrocarbon
intersection_of: RO:0016004 ENVO:00002005 ! has exposure medium air
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route
relationship: RO:0016004 ENVO:00002005 ! has exposure medium air

[Term]
id: ECTO:0080002
name: exposure to chlorpyrifos in apple via ingestion
def: "An exposure to chlorpyrifos mixed in apple via ingestion route." []
synonym: "chlorpyrifos exposure in apple via ingestion route" EXACT []
is_a: ECTO:0900088 ! exposure to phosphorus via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000633 ! exposure to chlorpyrifos
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:34631 ! has exposure stimulus chlorpyrifos
intersection_of: RO:0016004 FOODON:00002473 ! has exposure medium apple
relationship: RO:0016004 FOODON:00002473 ! has exposure medium apple

[Term]
id: ECTO:0080003
name: exposure to lead in water via ingestion
def: "An exposure to lead molecular entity mixed in liquid water via ingestion route." []
synonym: "lead molecular entity exposure in liquid water via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000945 ! exposure to lead
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33585 ! has exposure stimulus lead molecular entity
intersection_of: RO:0016004 ENVO:00002006 ! has exposure medium liquid water
relationship: RO:0016004 ENVO:00002006 ! has exposure medium liquid water

[Term]
id: ECTO:0080004
name: exposure to hydrogen chloride in air via inhalation
def: "An exposure to hydrogen chloride mixed in air via inhalation route." []
synonym: "hydrogen chloride exposure in air via inhalation route" EXACT []
is_a: ECTO:9000016 ! exposure to hydrogen chloride
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:17883 ! has exposure stimulus hydrogen chloride
intersection_of: RO:0016004 ENVO:00002005 ! has exposure medium air
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route
relationship: RO:0016004 ENVO:00002005 ! has exposure medium air

[Term]
id: ECTO:0080005
name: exposure to radon in air via inhalation
def: "An exposure to radon molecular entity mixed in air via inhalation route." []
synonym: "radon molecular entity exposure in air via inhalation route" EXACT []
is_a: ECTO:9000097 ! exposure to radon
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:36911 ! has exposure stimulus radon molecular entity
intersection_of: RO:0016004 ENVO:00002005 ! has exposure medium air
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route
relationship: RO:0016004 ENVO:00002005 ! has exposure medium air

[Term]
id: ECTO:0080006
name: exposure to calcium in water via ingestion
def: "An exposure to calcium molecular entity mixed in liquid water via ingestion route." []
synonym: "calcium molecular entity exposure in liquid water via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22985 ! has exposure stimulus calcium molecular entity
intersection_of: RO:0016004 ENVO:00002006 ! has exposure medium liquid water
relationship: RO:0002309 CHEBI:22985 ! has exposure stimulus calcium molecular entity
relationship: RO:0016004 ENVO:00002006 ! has exposure medium liquid water

[Term]
id: ECTO:0080007
name: exposure to magnesium in water via ingestion
def: "An exposure to magnesium molecular entity mixed in liquid water via ingestion route." []
synonym: "magnesium molecular entity exposure in liquid water via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25108 ! has exposure stimulus magnesium molecular entity
intersection_of: RO:0016004 ENVO:00002006 ! has exposure medium liquid water
relationship: RO:0002309 CHEBI:25108 ! has exposure stimulus magnesium molecular entity
relationship: RO:0016004 ENVO:00002006 ! has exposure medium liquid water

[Term]
id: ECTO:0090001
name: exposure to glucose in food
def: "An exposure to glucose mixed in food product." []
synonym: "glucose exposure in food product" EXACT []
is_a: ECTO:0090005 ! exposure to monosaccharide in food
is_a: ECTO:9000165 ! exposure to glucose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:17234 ! has exposure stimulus glucose

[Term]
id: ECTO:0090002
name: exposure to fructose in food
def: "An exposure to fructose mixed in food product." []
synonym: "fructose exposure in food product" EXACT []
is_a: ECTO:0090005 ! exposure to monosaccharide in food
is_a: ECTO:9000166 ! exposure to fructose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:28757 ! has exposure stimulus fructose

[Term]
id: ECTO:0090003
name: exposure to sucrose in food
def: "An exposure to sucrose mixed in food product." []
synonym: "sucrose exposure in food product" EXACT []
is_a: ECTO:9000163 ! exposure to sucrose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:17992 ! has exposure stimulus sucrose
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0090004
name: exposure to protein in food
def: "An exposure to protein mixed in food product." []
synonym: "protein exposure in food product" EXACT []
is_a: ECTO:9002133 ! exposure to protein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:36080 ! has exposure stimulus protein
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0090005
name: exposure to monosaccharide in food
def: "An exposure to monosaccharide mixed in food product." []
synonym: "monosaccharide exposure in food product" EXACT []
is_a: ECTO:9000239 ! exposure to monosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:35381 ! has exposure stimulus monosaccharide
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0090006
name: exposure to cholesterol in food
def: "An exposure to cholesterol mixed in food product." []
synonym: "cholesterol exposure in food product" EXACT []
is_a: ECTO:0090010 ! exposure to lipid in food
is_a: ECTO:9000310 ! exposure to cholesterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:16113 ! has exposure stimulus cholesterol

[Term]
id: ECTO:0090007
name: exposure to triglyceride in food
def: "An exposure to triglyceride mixed in food product." []
synonym: "triglyceride exposure in food product" EXACT []
is_a: ECTO:0090010 ! exposure to lipid in food
is_a: ECTO:9000236 ! exposure to triglyceride
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:17855 ! has exposure stimulus triglyceride

[Term]
id: ECTO:0090008
name: exposure to low-density lipoprotein in food
def: "An exposure to low-density lipoprotein mixed in food product." []
synonym: "low-density lipoprotein exposure in food product" EXACT []
is_a: ECTO:0090004 ! exposure to protein in food
is_a: ECTO:9002134 ! exposure to low-density lipoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:39026 ! has exposure stimulus low-density lipoprotein

[Term]
id: ECTO:0090009
name: exposure to high-density lipoprotein in food
def: "An exposure to high-density lipoprotein mixed in food product." []
synonym: "high-density lipoprotein exposure in food product" EXACT []
is_a: ECTO:0090004 ! exposure to protein in food
is_a: ECTO:9002135 ! exposure to high-density lipoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:39025 ! has exposure stimulus high-density lipoprotein

[Term]
id: ECTO:0090010
name: exposure to lipid in food
def: "An exposure to lipid mixed in food product." []
synonym: "lipid exposure in food product" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 FOODON:00001002 ! has exposure transport path food product
intersection_of: RO:0002309 CHEBI:18059 ! has exposure stimulus lipid
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0090011
name: exposure to paraquat in air
def: "An exposure to paraquat mixed in air." []
synonym: "paraquat exposure in air" EXACT []
is_a: ECTO:9000395 ! exposure to paraquat
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 ENVO:00002005 ! has exposure transport path air
intersection_of: RO:0002309 CHEBI:34905 ! has exposure stimulus paraquat
relationship: RO:0002243 ENVO:00002005 ! has exposure transport path air

[Term]
id: ECTO:0090012
name: exposure to paraquat in soil
def: "An exposure to paraquat mixed in soil." []
synonym: "paraquat exposure in soil" EXACT []
is_a: ECTO:9000395 ! exposure to paraquat
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 ENVO:00001998 ! has exposure transport path soil
intersection_of: RO:0002309 CHEBI:34905 ! has exposure stimulus paraquat
relationship: RO:0002243 ENVO:00001998 ! has exposure transport path soil

[Term]
id: ECTO:0090013
name: exposure to paraquat in water
def: "An exposure to paraquat mixed in liquid water." []
synonym: "paraquat exposure in liquid water" EXACT []
is_a: ECTO:9000395 ! exposure to paraquat
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 ENVO:00002006 ! has exposure transport path liquid water
intersection_of: RO:0002309 CHEBI:34905 ! has exposure stimulus paraquat
relationship: RO:0002243 ENVO:00002006 ! has exposure transport path liquid water

[Term]
id: ECTO:0090014
name: exposure to DDT in air
def: "An exposure to DDT mixed in air." []
synonym: "DDT exposure in air" EXACT []
is_a: ECTO:9000281 ! exposure to DDT
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 ENVO:00002005 ! has exposure transport path air
intersection_of: RO:0002309 CHEBI:16130 ! has exposure stimulus DDT
relationship: RO:0002243 ENVO:00002005 ! has exposure transport path air

[Term]
id: ECTO:0090015
name: exposure to DDT in soil
def: "An exposure to DDT mixed in soil." []
synonym: "DDT exposure in soil" EXACT []
is_a: ECTO:9000281 ! exposure to DDT
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 ENVO:00001998 ! has exposure transport path soil
intersection_of: RO:0002309 CHEBI:16130 ! has exposure stimulus DDT
relationship: RO:0002243 ENVO:00001998 ! has exposure transport path soil

[Term]
id: ECTO:0090016
name: exposure to DDT in water
def: "An exposure to DDT mixed in liquid water." []
synonym: "DDT exposure in liquid water" EXACT []
is_a: ECTO:9000281 ! exposure to DDT
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002243 ENVO:00002006 ! has exposure transport path liquid water
intersection_of: RO:0002309 CHEBI:16130 ! has exposure stimulus DDT
relationship: RO:0002243 ENVO:00002006 ! has exposure transport path liquid water

[Term]
id: ECTO:0100000
name: exposure to nicotine addictive consumption
def: "An exposure event involving nicotine consumption of an addictive substance" []
synonym: "nicotine consumption of an addictive substance exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100001
name: exposure to drinking alcohol
def: "An exposure event involving ethanol consumption of an addictive substance" []
synonym: "ethanol consumption of an addictive substance exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100002
name: exposure to smoking nicotine
def: "An exposure event involving nicotine smoking behavior" []
synonym: "nicotine smoking behavior exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100003
name: exposure to cigarette smoking
def: "An exposure event involving nicotine cigarette smoking behavior" []
synonym: "nicotine cigarette smoking behavior exposure" EXACT []
is_a: ECTO:0100002 ! exposure to smoking nicotine

[Term]
id: ECTO:0100004
name: exposure to cigar smoking
def: "An exposure event involving nicotine cigar smoking behavior" []
synonym: "nicotine cigar smoking behavior exposure" EXACT []
is_a: ECTO:0100002 ! exposure to smoking nicotine

[Term]
id: ECTO:0100005
name: exposure to cannabis
def: "An exposure event involving Cannabis sativa consumption of an addictive substance" []
synonym: "Cannabis sativa consumption of an addictive substance exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100006
name: exposure to morphiane alkaloid
def: "An exposure event involving morphinane alkaloid consumption of an addictive substance" []
synonym: "morphinane alkaloid consumption of an addictive substance exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100007
name: exposure to cocaine addictive consumption
def: "An exposure event involving cocaine consumption of an addictive substance" []
synonym: "cocaine consumption of an addictive substance exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100008
name: exposure to methamphetamine addictive consumption
def: "An exposure event involving methamphetamine consumption of an addictive substance" []
synonym: "methamphetamine consumption of an addictive substance exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100009
name: exposure to heroin addictive consumption
def: "An exposure event involving heroin consumption of an addictive substance" []
synonym: "heroin consumption of an addictive substance exposure" EXACT []
is_a: ECTO:0100006 ! exposure to morphiane alkaloid

[Term]
id: ECTO:0100010
name: exposure to tobacco pipe smoking
def: "An exposure event involving nicotine pipe smoking behavior" []
synonym: "nicotine pipe smoking behavior exposure" EXACT []
is_a: ECTO:0100002 ! exposure to smoking nicotine

[Term]
id: ECTO:0100011
name: exposure to tobacco chewing
def: "An exposure event involving nicotine tobacco chewing behavior" []
synonym: "nicotine tobacco chewing behavior exposure" EXACT []
is_a: ECTO:0100013 ! exposure to tobacco

[Term]
id: ECTO:0100012
name: exposure to snuffing
def: "An exposure event involving nicotine snuffing behavior" []
synonym: "nicotine snuffing behavior exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0100013
name: exposure to tobacco
def: "An exposure event involving nicotine tobacco consumption" []
synonym: "nicotine tobacco consumption exposure" EXACT []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:0200001
name: exposure to corticosteroid therapy via inhalation
def: "An exposure to inhaled corticosteroid agent therapy via inhalation route." []
synonym: "inhaled corticosteroid agent therapy exposure via inhalation route" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 MAXO:0000314 ! has exposure stimulus inhaled corticosteroid agent therapy
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route
relationship: RO:0002309 MAXO:0000314 ! has exposure stimulus inhaled corticosteroid agent therapy

[Term]
id: ECTO:0200002
name: exposure to glycemic agent therapy via ingestion
def: "An exposure to glycemic agent therapy via ingestion route." []
synonym: "glycemic agent therapy exposure via ingestion route" EXACT []
is_a: ECTO:2000035 ! exposure to glycemic agents
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 MAXO:0000258 ! has exposure stimulus glycemic agent therapy
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0200003
name: exposure to anticoagulant therapy via ingestion
def: "An exposure to anticoagulant agent therapy via ingestion route." []
synonym: "anticoagulant agent therapy exposure via ingestion route" EXACT []
is_a: ECTO:2000027 ! exposure to anticoagulants
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 MAXO:0000178 ! has exposure stimulus anticoagulant agent therapy
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0200004
name: exposure to maternal pharmacotherapy
def: "An exposure to pharmacotherapy via maternal." []
synonym: "pharmacotherapy exposure via maternal" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 MAXO:0000058 ! has exposure stimulus pharmacotherapy
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300000
name: exposure to nicotine via maternal
def: "An exposure event involving nicotine consumption of an addictive substance via maternal" []
synonym: "nicotine consumption of an addictive substance exposure via maternal" EXACT []
is_a: ECTO:0100000 ! exposure to nicotine addictive consumption
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300001
name: exposure to drinking alcohol via maternal
def: "An exposure event involving ethanol consumption of an addictive substance via maternal" []
synonym: "ethanol consumption of an addictive substance exposure via maternal" EXACT []
is_a: ECTO:0100001 ! exposure to drinking alcohol
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300002
name: exposure to smoking nicotine via maternal
def: "An exposure event involving nicotine smoking behavior via maternal" []
synonym: "nicotine smoking behavior exposure via maternal" EXACT []
is_a: ECTO:0100002 ! exposure to smoking nicotine
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300003
name: exposure to cigarette smoking via maternal
def: "An exposure event involving nicotine cigarette smoking behavior via maternal" []
synonym: "nicotine cigarette smoking behavior exposure via maternal" EXACT []
is_a: ECTO:0100003 ! exposure to cigarette smoking
is_a: ECTO:0300002 ! exposure to smoking nicotine via maternal

[Term]
id: ECTO:0300004
name: exposure to cigar smoking via maternal
def: "An exposure event involving nicotine cigar smoking behavior via maternal" []
synonym: "nicotine cigar smoking behavior exposure via maternal" EXACT []
is_a: ECTO:0100004 ! exposure to cigar smoking
is_a: ECTO:0300002 ! exposure to smoking nicotine via maternal

[Term]
id: ECTO:0300006
name: exposure to morphiane alkaloid via maternal
def: "An exposure event involving morphinane alkaloid consumption of an addictive substance via maternal" []
synonym: "morphinane alkaloid consumption of an addictive substance exposure via maternal" EXACT []
is_a: ECTO:0100006 ! exposure to morphiane alkaloid
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300007
name: exposure to cocaine via maternal
def: "An exposure event involving cocaine consumption of an addictive substance via maternal" []
synonym: "cocaine consumption of an addictive substance exposure via maternal" EXACT []
is_a: ECTO:0100007 ! exposure to cocaine addictive consumption
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300008
name: exposure to methamphetamine via maternal
def: "An exposure event involving methamphetamine consumption of an addictive substance via maternal" []
synonym: "methamphetamine consumption of an addictive substance exposure via maternal" EXACT []
is_a: ECTO:0100008 ! exposure to methamphetamine addictive consumption
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300009
name: exposure to heroin via maternal
def: "An exposure event involving heroin consumption of an addictive substance via maternal" []
synonym: "heroin consumption of an addictive substance exposure via maternal" EXACT []
is_a: ECTO:0100009 ! exposure to heroin addictive consumption
is_a: ECTO:0300006 ! exposure to morphiane alkaloid via maternal
is_a: ECTO:0300011 ! exposure to opioid agent via maternal

[Term]
id: ECTO:0300010
name: exposure to cannabinoid via maternal
def: "An exposure event involving cannabinoid consumption of an addictive substance via maternal" []
synonym: "cannabinoid consumption of an addictive substance exposure via maternal" EXACT []
is_a: ExO:0000002 ! exposure event
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0300011
name: exposure to opioid agent via maternal
def: "An exposure event involving opioid agent consumption of an addictive substance via maternal" []
synonym: "opioid agent consumption of an addictive substance exposure via maternal" EXACT []
is_a: ExO:0000002 ! exposure event
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0400000
name: exposure to environmental layer
def: "A exposure event involving the interaction of an exposure receptor to layer." []
synonym: "layer exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000281 ! has exposure stimulus layer
relationship: RO:0002309 ENVO:01000281 ! has exposure stimulus layer

[Term]
id: ECTO:0400001
name: exposure to increased salt in water
def: "A exposure event involving the interaction of an exposure receptor to increased amount of salt in liquid water." []
synonym: "increased amount exposure to salt in liquid water" EXACT []
is_a: ECTO:4000002 ! exposure to increased salt
relationship: RO:0002243 ENVO:00002006 ! has exposure transport path liquid water

[Term]
id: ECTO:0400002
name: exposure to decreased salt in water
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of salt in liquid water." []
synonym: "decreased amount exposure to salt in liquid water" EXACT []
is_a: ECTO:4000003 ! exposure to decreased salt
relationship: RO:0002243 ENVO:00002006 ! has exposure transport path liquid water

[Term]
id: ECTO:0400003
name: exposure to increased salt in soil
def: "A exposure event involving the interaction of an exposure receptor to increased amount of salt in soil." []
synonym: "increased amount exposure to salt in soil" EXACT []
is_a: ECTO:4000002 ! exposure to increased salt
relationship: RO:0002243 ENVO:00001998 ! has exposure transport path soil

[Term]
id: ECTO:0400004
name: exposure to decreased salt in soil
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of salt in soil." []
synonym: "decreased amount exposure to salt in soil" EXACT []
is_a: ECTO:4000003 ! exposure to decreased salt
relationship: RO:0002243 ENVO:00001998 ! has exposure transport path soil

[Term]
id: ECTO:0400005
name: exposure to increased methane in air
def: "A exposure event involving the interaction of an exposure receptor to increased amount of methane in air." []
synonym: "increased amount exposure to methane in air" EXACT []
is_a: ECTO:4000004 ! exposure to increased methane
relationship: RO:0002243 ENVO:00002005 ! has exposure transport path air

[Term]
id: ECTO:0400006
name: exposure to decreased methane in air
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of methane in air." []
synonym: "decreased amount exposure to methane in air" EXACT []
is_a: ECTO:4000005 ! exposure to decreased methane
relationship: RO:0002243 ENVO:00002005 ! has exposure transport path air

[Term]
id: ECTO:0400007
name: exposure to increased glucose in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of glucose in food product." []
synonym: "increased amount exposure to glucose in food product" EXACT []
is_a: ECTO:0400011 ! exposure to increased monosaccharide in food
is_a: ECTO:4000006 ! exposure to increased glucose

[Term]
id: ECTO:0400008
name: exposure to increased fructose in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of fructose in food product." []
synonym: "increased amount exposure to fructose in food product" EXACT []
is_a: ECTO:0400011 ! exposure to increased monosaccharide in food
is_a: ECTO:4000007 ! exposure to increased fructose

[Term]
id: ECTO:0400009
name: exposure to increased sucrose in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of sucrose in food product." []
synonym: "increased amount exposure to sucrose in food product" EXACT []
is_a: ECTO:4000008 ! exposure to increased sucrose
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400010
name: exposure to increased protein in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of protein in food product." []
synonym: "increased amount exposure to protein in food product" EXACT []
is_a: ECTO:4000009 ! exposure to increased protein
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400011
name: exposure to increased monosaccharide in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of monosaccharide in food product." []
synonym: "increased amount exposure to monosaccharide in food product" EXACT []
is_a: ECTO:4000010 ! exposure to increased monosaccharide
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400012
name: exposure to increased cholesterol in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of cholesterol in food product." []
synonym: "increased amount exposure to cholesterol in food product" EXACT []
is_a: ECTO:4000011 ! exposure to increased cholesterol
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400013
name: exposure to increased triglyceride in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of triglyceride in food product." []
synonym: "increased amount exposure to triglyceride in food product" EXACT []
is_a: ECTO:4000012 ! exposure to increased triglyceride
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400014
name: exposure to increased low-density lipoprotein in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of low-density lipoprotein in food product." []
synonym: "increased amount exposure to low-density lipoprotein in food product" EXACT []
is_a: ECTO:0400010 ! exposure to increased protein in food
is_a: ECTO:4000013 ! exposure to increased low-density lipoprotein

[Term]
id: ECTO:0400015
name: exposure to increased high-density lipoprotein in food
def: "A exposure event involving the interaction of an exposure receptor to increased amount of high-density lipoprotein in food product." []
synonym: "increased amount exposure to high-density lipoprotein in food product" EXACT []
is_a: ECTO:0400010 ! exposure to increased protein in food
is_a: ECTO:4000014 ! exposure to increased high-density lipoprotein

[Term]
id: ECTO:0400016
name: exposure to decreased glucose in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of glucose in food product." []
synonym: "decreased amount exposure to glucose in food product" EXACT []
is_a: ECTO:0400020 ! exposure to decreased monosaccharide in food
is_a: ECTO:4000015 ! exposure to decreased glucose

[Term]
id: ECTO:0400017
name: exposure to decreased fructose in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of fructose in food product." []
synonym: "decreased amount exposure to fructose in food product" EXACT []
is_a: ECTO:0400020 ! exposure to decreased monosaccharide in food
is_a: ECTO:4000016 ! exposure to decreased fructose

[Term]
id: ECTO:0400018
name: exposure to decreased sucrose in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of sucrose in food product." []
synonym: "decreased amount exposure to sucrose in food product" EXACT []
is_a: ECTO:4000017 ! exposure to decreased sucrose
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400019
name: exposure to decreased protein in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of protein in food product." []
synonym: "decreased amount exposure to protein in food product" EXACT []
is_a: ECTO:4000018 ! exposure to decreased protein
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400020
name: exposure to decreased monosaccharide in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of monosaccharide in food product." []
synonym: "decreased amount exposure to monosaccharide in food product" EXACT []
is_a: ECTO:4000019 ! exposure to decreased monosaccharide
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400021
name: exposure to decreased cholesterol in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of cholesterol in food product." []
synonym: "decreased amount exposure to cholesterol in food product" EXACT []
is_a: ECTO:4000020 ! exposure to decreased cholesterol
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400022
name: exposure to decreased triglyceride in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of triglyceride in food product." []
synonym: "decreased amount exposure to triglyceride in food product" EXACT []
is_a: ECTO:4000021 ! exposure to decreased triglyceride
relationship: RO:0002243 FOODON:00001002 ! has exposure transport path food product

[Term]
id: ECTO:0400023
name: exposure to decreased low-density lipoprotein in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of low-density lipoprotein in food product." []
synonym: "decreased amount exposure to low-density lipoprotein in food product" EXACT []
is_a: ECTO:0400019 ! exposure to decreased protein in food
is_a: ECTO:4000022 ! exposure to decreased low-density lipoprotein

[Term]
id: ECTO:0400024
name: exposure to decreased high-density lipoprotein in food
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of high-density lipoprotein in food product." []
synonym: "decreased amount exposure to high-density lipoprotein in food product" EXACT []
is_a: ECTO:0400019 ! exposure to decreased protein in food
is_a: ECTO:4000023 ! exposure to decreased high-density lipoprotein

[Term]
id: ECTO:0500000
name: exposure to environmental disposition
def: "A exposure event involving the interaction of an exposure receptor to environmental disposition." []
synonym: "environmental disposition exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000452 ! has exposure stimulus environmental disposition
relationship: RO:0002309 ENVO:01000452 ! has exposure stimulus environmental disposition

[Term]
id: ECTO:0500001
name: exposure to brake fluid
def: "A exposure event involving the interaction of an exposure receptor to brake fluid." []
synonym: "brake fluid exposure" EXACT []
is_a: ECTO:0500002 ! exposure to hydraulic fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510001 ! has exposure stimulus brake fluid
relationship: RO:0002309 ENVO:03510001 ! has exposure stimulus brake fluid

[Term]
id: ECTO:0500002
name: exposure to hydraulic fluid
def: "A exposure event involving the interaction of an exposure receptor to hydraulic fluid." []
synonym: "hydraulic fluid exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510004 ! has exposure stimulus hydraulic fluid
relationship: RO:0002309 ENVO:03510004 ! has exposure stimulus hydraulic fluid

[Term]
id: ECTO:0500003
name: exposure to automatic transmission fluid
def: "A exposure event involving the interaction of an exposure receptor to automatic transmission fluid." []
synonym: "automatic transmission fluid exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510002 ! has exposure stimulus automatic transmission fluid
relationship: RO:0002309 ENVO:03510002 ! has exposure stimulus automatic transmission fluid

[Term]
id: ECTO:0500004
name: exposure to motor oil
def: "A exposure event involving the interaction of an exposure receptor to motor oil." []
synonym: "motor oil exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510005 ! has exposure stimulus motor oil
relationship: RO:0002309 ENVO:03510005 ! has exposure stimulus motor oil

[Term]
id: ECTO:0500005
name: exposure to dye
def: "A exposure event involving the interaction of an exposure receptor to dye." []
synonym: "dye exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510010 ! has exposure stimulus dye
relationship: RO:0002309 ENVO:03510010 ! has exposure stimulus dye

[Term]
id: ECTO:0500006
name: exposure to leather dye
def: "A exposure event involving the interaction of an exposure receptor to leather dye." []
synonym: "leather dye exposure" EXACT []
is_a: ECTO:0500005 ! exposure to dye
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510011 ! has exposure stimulus leather dye
relationship: RO:0002309 ENVO:03510011 ! has exposure stimulus leather dye

[Term]
id: ECTO:0500007
name: exposure to paper dye
def: "A exposure event involving the interaction of an exposure receptor to paper dye." []
synonym: "paper dye exposure" EXACT []
is_a: ECTO:0500005 ! exposure to dye
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510012 ! has exposure stimulus paper dye
relationship: RO:0002309 ENVO:03510012 ! has exposure stimulus paper dye

[Term]
id: ECTO:0500008
name: exposure to textile dye
def: "A exposure event involving the interaction of an exposure receptor to textile dye." []
synonym: "textile dye exposure" EXACT []
is_a: ECTO:0500005 ! exposure to dye
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510013 ! has exposure stimulus textile dye
relationship: RO:0002309 ENVO:03510013 ! has exposure stimulus textile dye

[Term]
id: ECTO:0500009
name: exposure to India ink
def: "A exposure event involving the interaction of an exposure receptor to India ink." []
synonym: "India ink exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510014 ! has exposure stimulus India ink
relationship: RO:0002309 ENVO:03510014 ! has exposure stimulus India ink

[Term]
id: ECTO:0500010
name: exposure to fountain pen ink
def: "A exposure event involving the interaction of an exposure receptor to fountain pen ink." []
synonym: "fountain pen ink exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510017 ! has exposure stimulus fountain pen ink
relationship: RO:0002309 ENVO:03510017 ! has exposure stimulus fountain pen ink

[Term]
id: ECTO:0500011
name: exposure to cleaning agent
def: "A exposure event involving the interaction of an exposure receptor to cleaning agent." []
synonym: "cleaning agent exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510019 ! has exposure stimulus cleaning agent
relationship: RO:0002309 ENVO:03510019 ! has exposure stimulus cleaning agent

[Term]
id: ECTO:0500012
name: exposure to degreaser
def: "A exposure event involving the interaction of an exposure receptor to degreaser." []
synonym: "degreaser exposure" EXACT []
is_a: ECTO:0500011 ! exposure to cleaning agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510020 ! has exposure stimulus degreaser
relationship: RO:0002309 ENVO:03510020 ! has exposure stimulus degreaser

[Term]
id: ECTO:0500013
name: exposure to varnish
def: "A exposure event involving the interaction of an exposure receptor to varnish." []
synonym: "varnish exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510021 ! has exposure stimulus varnish
relationship: RO:0002309 ENVO:03510021 ! has exposure stimulus varnish

[Term]
id: ECTO:0500014
name: exposure to resin (gum) varnish
def: "A exposure event involving the interaction of an exposure receptor to resin (gum) varnish." []
synonym: "resin (gum) varnish exposure" EXACT []
is_a: ECTO:0500013 ! exposure to varnish
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510022 ! has exposure stimulus resin (gum) varnish
relationship: RO:0002309 ENVO:03510022 ! has exposure stimulus resin (gum) varnish

[Term]
id: ECTO:0500015
name: exposure to stain
def: "A exposure event involving the interaction of an exposure receptor to stain." []
synonym: "stain exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510040 ! has exposure stimulus stain
relationship: RO:0002309 ENVO:03510040 ! has exposure stimulus stain

[Term]
id: ECTO:0500016
name: exposure to wood stain
def: "A exposure event involving the interaction of an exposure receptor to wood stain." []
synonym: "wood stain exposure" EXACT []
is_a: ECTO:0500015 ! exposure to stain
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510041 ! has exposure stimulus wood stain
relationship: RO:0002309 ENVO:03510041 ! has exposure stimulus wood stain

[Term]
id: ECTO:0500017
name: exposure to lacquer
def: "A exposure event involving the interaction of an exposure receptor to lacquer." []
synonym: "lacquer exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510024 ! has exposure stimulus lacquer
relationship: RO:0002309 ENVO:03510024 ! has exposure stimulus lacquer

[Term]
id: ECTO:0500018
name: exposure to oil paint thinner
def: "A exposure event involving the interaction of an exposure receptor to oil paint thinner." []
synonym: "oil paint thinner exposure" EXACT []
is_a: ECTO:0500024 ! exposure to paint thinner
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510028 ! has exposure stimulus oil paint thinner
relationship: RO:0002309 ENVO:03510028 ! has exposure stimulus oil paint thinner

[Term]
id: ECTO:0500019
name: exposure to acrylic paint medium
def: "A exposure event involving the interaction of an exposure receptor to acrylic paint medium." []
synonym: "acrylic paint medium exposure" EXACT []
is_a: ECTO:0500024 ! exposure to paint thinner
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510026 ! has exposure stimulus acrylic paint medium
relationship: RO:0002309 ENVO:03510026 ! has exposure stimulus acrylic paint medium

[Term]
id: ECTO:0500020
name: exposure to enamel thinner
def: "A exposure event involving the interaction of an exposure receptor to enamel thinner." []
synonym: "enamel thinner exposure" EXACT []
is_a: ECTO:0500024 ! exposure to paint thinner
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510027 ! has exposure stimulus enamel thinner
relationship: RO:0002309 ENVO:03510027 ! has exposure stimulus enamel thinner

[Term]
id: ECTO:0500021
name: exposure to vitreous enamel
def: "A exposure event involving the interaction of an exposure receptor to vitreous enamel." []
synonym: "vitreous enamel exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510030 ! has exposure stimulus vitreous enamel
relationship: RO:0002309 ENVO:03510030 ! has exposure stimulus vitreous enamel

[Term]
id: ECTO:0500022
name: exposure to turpentine
def: "A exposure event involving the interaction of an exposure receptor to turpentine." []
synonym: "turpentine exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510034 ! has exposure stimulus turpentine
relationship: RO:0002309 ENVO:03510034 ! has exposure stimulus turpentine

[Term]
id: ECTO:0500023
name: exposure to naphtha
def: "A exposure event involving the interaction of an exposure receptor to naphtha." []
synonym: "naphtha exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510035 ! has exposure stimulus naphtha
relationship: RO:0002309 ENVO:03510035 ! has exposure stimulus naphtha

[Term]
id: ECTO:0500024
name: exposure to paint thinner
def: "A exposure event involving the interaction of an exposure receptor to paint thinner." []
synonym: "paint thinner exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510025 ! has exposure stimulus paint thinner
relationship: RO:0002309 ENVO:03510025 ! has exposure stimulus paint thinner

[Term]
id: ECTO:0500025
name: exposure to manufactured product
def: "A exposure event involving the interaction of an exposure receptor to manufactured product." []
synonym: "manufactured product exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003074 ! has exposure stimulus manufactured product
relationship: RO:0002309 ENVO:00003074 ! has exposure stimulus manufactured product

[Term]
id: ECTO:0600000
name: exposure to environmental system
def: "A exposure event involving the interaction of an exposure receptor to environmental system." []
synonym: "environmental system exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000254 ! has exposure stimulus environmental system
relationship: RO:0002309 ENVO:01000254 ! has exposure stimulus environmental system

[Term]
id: ECTO:0600001
name: exposure to aquaculture farm
def: "A exposure event involving the interaction of an exposure receptor to aquaculture farm." []
synonym: "aquaculture farm exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03600074 ! has exposure stimulus aquaculture farm
relationship: RO:0002309 ENVO:03600074 ! has exposure stimulus aquaculture farm

[Term]
id: ECTO:0600002
name: exposure to child care environment
def: "A exposure event involving the interaction of an exposure receptor to child care environment." []
synonym: "child care environment exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03501333 ! has exposure stimulus child care environment
relationship: RO:0002309 ENVO:03501333 ! has exposure stimulus child care environment

[Term]
id: ECTO:0600003
name: exposure to cold room
def: "A exposure event involving the interaction of an exposure receptor to cold room." []
synonym: "cold room exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03600035 ! has exposure stimulus cold room
relationship: RO:0002309 ENVO:03600035 ! has exposure stimulus cold room

[Term]
id: ECTO:0600004
name: exposure to grassland ecosystem
def: "A exposure event involving the interaction of an exposure receptor to grassland ecosystem." []
synonym: "grassland ecosystem exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001206 ! has exposure stimulus grassland ecosystem
relationship: RO:0002309 ENVO:01001206 ! has exposure stimulus grassland ecosystem

[Term]
id: ECTO:0600005
name: exposure to thermal pollution of an aquatic system
def: "A exposure event involving the interaction of an exposure receptor to thermal pollution of an aquatic system." []
synonym: "thermal pollution of an aquatic system exposure" EXACT []
is_a: ECTO:8000038 ! exposure to water pollution
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001266 ! has exposure stimulus thermal pollution of an aquatic system
relationship: RO:0002309 ENVO:01001266 ! has exposure stimulus thermal pollution of an aquatic system

[Term]
id: ECTO:0600006
name: exposure to carbonate system of ocean water
def: "A exposure event involving the interaction of an exposure receptor to carbonate system of ocean water." []
synonym: "carbonate system of ocean water exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001497 ! has exposure stimulus carbonate system of ocean water
relationship: RO:0002309 ENVO:01001497 ! has exposure stimulus carbonate system of ocean water

[Term]
id: ECTO:0600007
name: exposure to space station
def: "A exposure event involving the interaction of an exposure receptor to space station." []
synonym: "space station exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03600050 ! has exposure stimulus space station
relationship: RO:0002309 ENVO:03600050 ! has exposure stimulus space station

[Term]
id: ECTO:0600008
name: exposure to outer space
def: "A exposure event involving the interaction of an exposure receptor to outer space." []
synonym: "outer space exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000637 ! has exposure stimulus outer space
relationship: RO:0002309 ENVO:01000637 ! has exposure stimulus outer space

[Term]
id: ECTO:0600009
name: exposure to marine environment
def: "A exposure event involving the interaction of an exposure receptor to marine environment." []
synonym: "marine environment exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000320 ! has exposure stimulus marine environment
relationship: RO:0002309 ENVO:01000320 ! has exposure stimulus marine environment

[Term]
id: ECTO:0600010
name: exposure to estuary
def: "A exposure event involving the interaction of an exposure receptor to estuary." []
synonym: "estuary exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00000045 ! has exposure stimulus estuary
relationship: RO:0002309 ENVO:00000045 ! has exposure stimulus estuary

[Term]
id: ECTO:0600011
name: exposure to vineyard
def: "A exposure event involving the interaction of an exposure receptor to vineyard." []
synonym: "vineyard exposure" EXACT []
is_a: ECTO:1000034 ! exposure to farm
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00000116 ! has exposure stimulus vineyard
relationship: RO:0002309 ENVO:00000116 ! has exposure stimulus vineyard

[Term]
id: ECTO:0700001
name: exposure to ultrafine respirable suspended particulate matter via inhalation
def: "A exposure event involving the interaction of an exposure receptor to ultrafine respirable suspended particulate matter via inhalation route." []
synonym: "ultrafine respirable suspended particulate matter exposure via inhalation route" EXACT []
is_a: ECTO:0700002 ! exposure to aerosol via inhalation
is_a: ECTO:7000118 ! exposure to ultrafine respirable suspended particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 ENVO:01000416 ! has exposure stimulus ultrafine respirable suspended particulate matter

[Term]
id: ECTO:0700002
name: exposure to aerosol via inhalation
def: "A exposure event involving the interaction of an exposure receptor to aerosol via inhalation route." []
synonym: "aerosol exposure via inhalation route" EXACT []
is_a: ECTO:7000114 ! exposure to aerosol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 ENVO:00010505 ! has exposure stimulus aerosol
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0700003
name: exposure to red meat via ingestion
def: "A exposure event involving the interaction of an exposure receptor to red meat (eurofir) via ingestion route." []
synonym: "red meat (eurofir) exposure via ingestion route" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 FOODON:03400794 ! has exposure stimulus red meat (eurofir)
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route
relationship: RO:0002309 FOODON:03400794 ! has exposure stimulus red meat (eurofir)

[Term]
id: ECTO:0800001
name: exposure to environmental process route
def: "A exposure event involving the interaction of an exposure receptor to environmental system process happening in exposure route of the receptor." []
synonym: "environmental system process exposure in exposure route" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000055 ! has exposure route exposure route
intersection_of: RO:0002309 ENVO:02500000 ! has exposure stimulus environmental system process
relationship: RO:0002242 ExO:0000055 ! has exposure route exposure route

[Term]
id: ECTO:0800002
name: exposure to air pollution via maternal
def: "A exposure event involving the interaction of an exposure receptor to air pollution happening in maternal of the receptor." []
synonym: "air pollution exposure in maternal" EXACT []
is_a: ECTO:0800001 ! exposure to environmental process route
is_a: ECTO:8000036 ! exposure to air pollution
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 ENVO:02500037 ! has exposure stimulus air pollution
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0800003
name: exposure to famine via maternal
def: "A exposure event involving the interaction of an exposure receptor to famine happening in maternal of the receptor." []
synonym: "famine exposure in maternal" EXACT []
is_a: ECTO:0800001 ! exposure to environmental process route
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 ENVO:03510003 ! has exposure stimulus famine
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal
relationship: RO:0002309 ENVO:03510003 ! has exposure stimulus famine

[Term]
id: ECTO:0900001
name: exposure to oral steroids
def: "An exposure to steroid via ingestion route." []
synonym: "steroid exposure via ingestion route" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:0900406 ! exposure to lipid via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35341 ! has exposure stimulus steroid

[Term]
id: ECTO:0900002
name: exposure to aflatoxin via ingestion
def: "An exposure to aflatoxin via ingestion route." []
synonym: "aflatoxin exposure via ingestion route" EXACT []
is_a: ECTO:0001108 ! exposure to aflatoxin
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22271 ! has exposure stimulus aflatoxin

[Term]
id: ECTO:0900003
name: exposure to antimony via ingestion
def: "An exposure to antimony molecular entity via ingestion route." []
synonym: "antimony molecular entity exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000939 ! exposure to antimony
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:36919 ! has exposure stimulus antimony molecular entity

[Term]
id: ECTO:0900004
name: exposure to arsenic via ingestion
def: "An exposure to arsenic molecular entity via ingestion route." []
synonym: "arsenic molecular entity exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000032 ! exposure to arsenic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22632 ! has exposure stimulus arsenic molecular entity

[Term]
id: ECTO:0900005
name: exposure to cadmium via ingestion
def: "An exposure to cadmium molecular entity via ingestion route." []
synonym: "cadmium molecular entity exposure via ingestion route" EXACT []
is_a: ECTO:0001566 ! exposure to cadmium
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22978 ! has exposure stimulus cadmium molecular entity

[Term]
id: ECTO:0900006
name: exposure to mercury via ingestion
def: "An exposure to mercury molecular entity via ingestion route." []
synonym: "mercury molecular entity exposure via ingestion route" EXACT []
is_a: ECTO:0001571 ! exposure to mercury
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25196 ! has exposure stimulus mercury molecular entity

[Term]
id: ECTO:0900007
name: exposure to bisphenol A via ingestion
def: "An exposure to bisphenol A via ingestion route." []
synonym: "bisphenol A exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000057 ! exposure to bisphenol A
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33216 ! has exposure stimulus bisphenol A

[Term]
id: ECTO:0900008
name: exposure to monosodium glutamate via ingestion
def: "An exposure to monosodium glutamate via ingestion route." []
synonym: "monosodium glutamate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000454 ! exposure to monosodium glutamate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:64220 ! has exposure stimulus monosodium glutamate

[Term]
id: ECTO:0900009
name: exposure to disodium 5'-guanylate via ingestion
def: "An exposure to disodium 5'-guanylate via ingestion route." []
synonym: "disodium 5'-guanylate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001540 ! exposure to disodium 5'-guanylate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:132932 ! has exposure stimulus disodium 5'-guanylate

[Term]
id: ECTO:0900010
name: exposure to food additive via ingestion
def: "An exposure to food additive via ingestion route." []
synonym: "food additive exposure via ingestion route" EXACT []
is_a: ECTO:0900120 ! exposure to food component via ingestion
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:64047 ! has exposure stimulus food additive

[Term]
id: ECTO:0900011
name: exposure to sweetening agent via ingestion
def: "An exposure to sweetening agent via ingestion route." []
synonym: "sweetening agent exposure via ingestion route" EXACT []
is_a: ECTO:0900014 ! exposure to flavoring agent via ingestion
is_a: ECTO:9001852 ! exposure to sweetening agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50505 ! has exposure stimulus sweetening agent

[Term]
id: ECTO:0900012
name: exposure to food preservative via ingestion
def: "An exposure to food preservative via ingestion route." []
synonym: "food preservative exposure via ingestion route" EXACT []
is_a: ECTO:0900010 ! exposure to food additive via ingestion
is_a: ECTO:9002130 ! exposure to food preservative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:65255 ! has exposure stimulus food preservative

[Term]
id: ECTO:0900013
name: exposure to food coloring via ingestion
def: "An exposure to food colouring via ingestion route." []
synonym: "food colouring exposure via ingestion route" EXACT []
is_a: ECTO:0900010 ! exposure to food additive via ingestion
is_a: ECTO:9002044 ! exposure to food colouring
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:77182 ! has exposure stimulus food colouring

[Term]
id: ECTO:0900014
name: exposure to flavoring agent via ingestion
def: "An exposure to flavouring agent via ingestion route." []
synonym: "flavouring agent exposure via ingestion route" EXACT []
is_a: ECTO:0900010 ! exposure to food additive via ingestion
is_a: ECTO:9001738 ! exposure to flavouring agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35617 ! has exposure stimulus flavouring agent

[Term]
id: ECTO:0900015
name: exposure to food emulsifier via ingestion
def: "An exposure to food emulsifier via ingestion route." []
synonym: "food emulsifier exposure via ingestion route" EXACT []
is_a: ECTO:0900010 ! exposure to food additive via ingestion
is_a: ECTO:9001930 ! exposure to food emulsifier
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:63047 ! has exposure stimulus food emulsifier

[Term]
id: ECTO:0900017
name: exposure to cadmium cation via ingestion
def: "An exposure to cadmium cation via ingestion route." []
synonym: "cadmium cation exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000286 ! exposure to cadmium cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:63063 ! has exposure stimulus cadmium cation

[Term]
id: ECTO:0900018
name: exposure to mercury cation via ingestion
def: "An exposure to mercury cation via ingestion route." []
synonym: "mercury cation exposure via ingestion route" EXACT []
is_a: ECTO:0900006 ! exposure to mercury via ingestion
is_a: ECTO:9000289 ! exposure to mercury cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25197 ! has exposure stimulus mercury cation

[Term]
id: ECTO:0900019
name: exposure to heroin via injection
def: "An exposure to heroin via injection route." []
synonym: "heroin exposure via injection route" EXACT []
is_a: ECTO:9001386 ! exposure to heroin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:27808 ! has exposure stimulus heroin
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900020
name: exposure to heroin via inhalation
def: "An exposure to heroin via inhalation route." []
synonym: "heroin exposure via inhalation route" EXACT []
is_a: ECTO:9001386 ! exposure to heroin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:27808 ! has exposure stimulus heroin
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900021
name: exposure to methamphetamine via injection
def: "An exposure to methamphetamine via injection route." []
synonym: "methamphetamine exposure via injection route" EXACT []
is_a: ECTO:9000769 ! exposure to methamphetamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:6809 ! has exposure stimulus methamphetamine
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900022
name: exposure to methamphetamine via inhalation
def: "An exposure to methamphetamine via inhalation route." []
synonym: "methamphetamine exposure via inhalation route" EXACT []
is_a: ECTO:9000769 ! exposure to methamphetamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:6809 ! has exposure stimulus methamphetamine
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900023
name: exposure to polycyclic hydrocarbon via maternal
def: "An exposure to polycyclic hydrocarbon via maternal." []
synonym: "polycyclic hydrocarbon exposure via maternal" EXACT []
is_a: ECTO:9002148 ! exposure to polycyclic hydrocarbon
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:33666 ! has exposure stimulus polycyclic hydrocarbon
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900024
name: exposure to vitamin A via ingestion
def: "An exposure to vitamin A via ingestion route." []
synonym: "vitamin A exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000125 ! exposure to vitamin A
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:12777 ! has exposure stimulus vitamin A

[Term]
id: ECTO:0900025
name: exposure to vitamin D via ingestion
def: "An exposure to vitamin D via ingestion route." []
synonym: "vitamin D exposure via ingestion route" EXACT []
is_a: ECTO:0900001 ! exposure to oral steroids
is_a: ECTO:9000133 ! exposure to vitamin D
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27300 ! has exposure stimulus vitamin D

[Term]
id: ECTO:0900026
name: exposure to vitamin E via ingestion
def: "An exposure to vitamin E via ingestion route." []
synonym: "vitamin E exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000224 ! exposure to vitamin E
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33234 ! has exposure stimulus vitamin E

[Term]
id: ECTO:0900027
name: exposure to vitamin K via ingestion
def: "An exposure to vitamin K via ingestion route." []
synonym: "vitamin K exposure via ingestion route" EXACT []
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000139 ! exposure to vitamin K
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28384 ! has exposure stimulus vitamin K

[Term]
id: ECTO:0900028
name: exposure to vitamin C via ingestion
def: "An exposure to vitamin C via ingestion route." []
synonym: "vitamin C exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000143 ! exposure to vitamin C
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:176783 ! has exposure stimulus vitamin C

[Term]
id: ECTO:0900029
name: exposure to vitamin B via ingestion
def: "An exposure to B vitamin via ingestion route." []
synonym: "B vitamin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:75769 ! has exposure stimulus B vitamin

[Term]
id: ECTO:0900030
name: exposure to vitamin B6 via ingestion
def: "An exposure to vitamin B6 via ingestion route." []
synonym: "vitamin B6 exposure via ingestion route" EXACT []
is_a: ECTO:0900029 ! exposure to vitamin B via ingestion
is_a: ECTO:9000243 ! exposure to vitamin B6
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27306 ! has exposure stimulus vitamin B6

[Term]
id: ECTO:0900031
name: exposure to cobalamin via ingestion
def: "An exposure to cobalamin via ingestion route." []
synonym: "cobalamin exposure via ingestion route" EXACT []
is_a: ECTO:0900029 ! exposure to vitamin B via ingestion
is_a: ECTO:9000229 ! exposure to cobalamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:30411 ! has exposure stimulus cobalamin

[Term]
id: ECTO:0900032
name: exposure to niacin (b3) via ingestion
def: "An exposure to nicotinic acid via ingestion route." []
synonym: "nicotinic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900029 ! exposure to vitamin B via ingestion
is_a: ECTO:0900477 ! exposure to alkaloid via ingestion
is_a: ECTO:9002151 ! exposure to niacin(b3)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15940 ! has exposure stimulus nicotinic acid

[Term]
id: ECTO:0900033
name: exposure to calcium via ingestion
def: "An exposure to calcium atom via ingestion route." []
synonym: "calcium atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22984 ! has exposure stimulus calcium atom
relationship: RO:0002309 CHEBI:22984 ! has exposure stimulus calcium atom

[Term]
id: ECTO:0900034
name: exposure to chromium via ingestion
def: "An exposure to chromium atom via ingestion route." []
synonym: "chromium atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28073 ! has exposure stimulus chromium atom
relationship: RO:0002309 CHEBI:28073 ! has exposure stimulus chromium atom

[Term]
id: ECTO:0900035
name: exposure to iron via ingestion
def: "An exposure to iron atom via ingestion route." []
synonym: "iron atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18248 ! has exposure stimulus iron atom
relationship: RO:0002309 CHEBI:18248 ! has exposure stimulus iron atom

[Term]
id: ECTO:0900036
name: exposure to folic acid via ingestion
def: "An exposure to folic acid via ingestion route." []
synonym: "folic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900029 ! exposure to vitamin B via ingestion
is_a: ECTO:9000123 ! exposure to folic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27470 ! has exposure stimulus folic acid

[Term]
id: ECTO:0900037
name: exposure to potassium via ingestion
def: "An exposure to potassium atom via ingestion route." []
synonym: "potassium atom exposure via ingestion route" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26216 ! has exposure stimulus potassium atom
relationship: RO:0002309 CHEBI:26216 ! has exposure stimulus potassium atom

[Term]
id: ECTO:0900038
name: exposure to selenium via ingestion
def: "An exposure to selenium atom via ingestion route." []
synonym: "selenium atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002591 ! exposure to selenium atom
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27568 ! has exposure stimulus selenium atom

[Term]
id: ECTO:0900039
name: exposure to zinc via ingestion
def: "An exposure to zinc atom via ingestion route." []
synonym: "zinc atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27363 ! has exposure stimulus zinc atom
relationship: RO:0002309 CHEBI:27363 ! has exposure stimulus zinc atom

[Term]
id: ECTO:0900040
name: exposure to magnesium via ingestion
def: "An exposure to magnesium atom via ingestion route." []
synonym: "magnesium atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002465 ! exposure to magnesium atom
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25107 ! has exposure stimulus magnesium atom

[Term]
id: ECTO:0900041
name: exposure to deoxynivalenol via ingestion
def: "An exposure to deoxynivalenol via ingestion route." []
synonym: "deoxynivalenol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002330 ! exposure to deoxynivalenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:10022 ! has exposure stimulus deoxynivalenol

[Term]
id: ECTO:0900042
name: exposure to chemical entity via ingestion
def: "An exposure to chemical entity via ingestion route." []
synonym: "chemical entity exposure via ingestion route" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:24431 ! has exposure stimulus chemical entity
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900043
name: exposure to drug via maternal
def: "An exposure to drug via maternal." []
synonym: "drug exposure via maternal" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:23888 ! has exposure stimulus drug
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900044
name: exposure to serotonin uptake inhibitor via maternal
def: "An exposure to serotonin uptake inhibitor via maternal." []
synonym: "serotonin uptake inhibitor exposure via maternal" EXACT []
is_a: ECTO:0900043 ! exposure to drug via maternal
is_a: ECTO:9001883 ! exposure to serotonin uptake inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:50949 ! has exposure stimulus serotonin uptake inhibitor

[Term]
id: ECTO:0900045
name: exposure to lead via maternal
def: "An exposure to lead atom via maternal." []
synonym: "lead atom exposure via maternal" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:25016 ! has exposure stimulus lead atom
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal
relationship: RO:0002309 CHEBI:25016 ! has exposure stimulus lead atom

[Term]
id: ECTO:0900046
name: exposure to glucose via ingestion
def: "An exposure to glucose via ingestion route." []
synonym: "glucose exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9000165 ! exposure to glucose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17234 ! has exposure stimulus glucose

[Term]
id: ECTO:0900047
name: exposure to allergen via inhalation
def: "An exposure to allergen via inhalation route." []
synonym: "allergen exposure via inhalation route" EXACT []
is_a: ECTO:0000726 ! exposure to allergen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:50904 ! has exposure stimulus allergen
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900048
name: exposure to protein via ingestion
def: "An exposure to protein via ingestion route." []
synonym: "protein exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002133 ! exposure to protein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:36080 ! has exposure stimulus protein

[Term]
id: ECTO:0900049
name: exposure to caffeine via ingestion
def: "An exposure to caffeine via ingestion route." []
synonym: "caffeine exposure via ingestion route" EXACT []
is_a: ECTO:0900477 ! exposure to alkaloid via ingestion
is_a: ECTO:9000205 ! exposure to caffeine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27732 ! has exposure stimulus caffeine

[Term]
id: ECTO:0900050
name: exposure to carbohydrate via ingestion
def: "An exposure to carbohydrate via ingestion route." []
synonym: "carbohydrate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000162 ! exposure to carbohydrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16646 ! has exposure stimulus carbohydrate

[Term]
id: ECTO:0900051
name: exposure to dextran sulfate sodium via ingestion
def: "An exposure to dextran sulfate sodium via ingestion route." []
synonym: "dextran sulfate sodium exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002333 ! exposure to dextran sulfate sodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:191875 ! has exposure stimulus dextran sulfate sodium

[Term]
id: ECTO:0900052
name: exposure to omega-3 fatty acid via ingestion
def: "An exposure to omega-3 fatty acid via ingestion route." []
synonym: "omega-3 fatty acid exposure via ingestion route" EXACT []
is_a: ECTO:0900053 ! exposure to polyunsaturated fatty acid via ingestion
is_a: ECTO:9002766 ! exposure to omega-3 fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25681 ! has exposure stimulus omega-3 fatty acid

[Term]
id: ECTO:0900053
name: exposure to polyunsaturated fatty acid via ingestion
def: "An exposure to polyunsaturated fatty acid via ingestion route." []
synonym: "polyunsaturated fatty acid exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002507 ! exposure to polyunsaturated fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26208 ! has exposure stimulus polyunsaturated fatty acid

[Term]
id: ECTO:0900054
name: exposure to aspirin via ingestion
def: "An exposure to acetylsalicylic acid via ingestion route." []
synonym: "acetylsalicylic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000008 ! exposure to aspirin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15365 ! has exposure stimulus acetylsalicylic acid

[Term]
id: ECTO:0900055
name: exposure to polysaccharide via ingestion
def: "An exposure to polysaccharide via ingestion route." []
synonym: "polysaccharide exposure via ingestion route" EXACT []
is_a: ECTO:0900050 ! exposure to carbohydrate via ingestion
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18154 ! has exposure stimulus polysaccharide

[Term]
id: ECTO:0900056
name: exposure to nutrient via ingestion
def: "An exposure to nutrient via ingestion route." []
synonym: "nutrient exposure via ingestion route" EXACT []
is_a: ECTO:0900120 ! exposure to food component via ingestion
is_a: ECTO:9001695 ! exposure to nutrient
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33284 ! has exposure stimulus nutrient

[Term]
id: ECTO:0900057
name: exposure to linoleic acid via ingestion
def: "An exposure to linoleic acid via ingestion route." []
synonym: "linoleic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900053 ! exposure to polyunsaturated fatty acid via ingestion
is_a: ECTO:9002837 ! exposure to linoleic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17351 ! has exposure stimulus linoleic acid

[Term]
id: ECTO:0900058
name: exposure to bile acids via ingestion
def: "An exposure to bile acids via ingestion route." []
synonym: "bile acids exposure via ingestion route" EXACT []
is_a: ECTO:0900001 ! exposure to oral steroids
is_a: ECTO:9002726 ! exposure to bile acids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:138366 ! has exposure stimulus bile acids

[Term]
id: ECTO:0900059
name: exposure to peptide via ingestion
def: "An exposure to peptide via ingestion route." []
synonym: "peptide exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16670 ! has exposure stimulus peptide

[Term]
id: ECTO:0900060
name: exposure to all-cis-docosa-4,7,10,13,16,19-hexaenoic acid via ingestion
def: "An exposure to all-cis-docosa-4,7,10,13,16,19-hexaenoic acid via ingestion route." []
synonym: "all-cis-docosa-4,7,10,13,16,19-hexaenoic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900052 ! exposure to omega-3 fatty acid via ingestion
is_a: ECTO:9002343 ! exposure to all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28125 ! has exposure stimulus all-cis-docosa-4,7,10,13,16,19-hexaenoic acid

[Term]
id: ECTO:0900061
name: exposure to glycerol via ingestion
def: "An exposure to glycerol via ingestion route." []
synonym: "glycerol exposure via ingestion route" EXACT []
is_a: ECTO:0900050 ! exposure to carbohydrate via ingestion
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:9001576 ! exposure to glycerol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17754 ! has exposure stimulus glycerol

[Term]
id: ECTO:0900062
name: exposure to fullerene via inhalation
def: "An exposure to fullerene via inhalation route." []
synonym: "fullerene exposure via inhalation route" EXACT []
is_a: ECTO:9002796 ! exposure to fullerene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:33416 ! has exposure stimulus fullerene
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900063
name: exposure to perfluorooctane-1-sulfonic acid via ingestion
def: "An exposure to perfluorooctane-1-sulfonic acid via ingestion route." []
synonym: "perfluorooctane-1-sulfonic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000094 ! exposure to perfluorooctane-1-sulfonic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:39421 ! has exposure stimulus perfluorooctane-1-sulfonic acid

[Term]
id: ECTO:0900064
name: exposure to statin via ingestion
def: "An exposure to statin via ingestion route." []
synonym: "statin exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000259 ! exposure to statin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:87631 ! has exposure stimulus statin

[Term]
id: ECTO:0900065
name: exposure to sucrose via ingestion
def: "An exposure to sucrose via ingestion route." []
synonym: "sucrose exposure via ingestion route" EXACT []
is_a: ECTO:0900320 ! exposure to oligosaccharide via ingestion
is_a: ECTO:9000163 ! exposure to sucrose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17992 ! has exposure stimulus sucrose

[Term]
id: ECTO:0900066
name: exposure to 6-propyl-2-thiouracil via ingestion
def: "An exposure to 6-propyl-2-thiouracil via ingestion route." []
synonym: "6-propyl-2-thiouracil exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002240 ! exposure to 6-propyl-2-thiouracil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8502 ! has exposure stimulus 6-propyl-2-thiouracil

[Term]
id: ECTO:0900067
name: exposure to ginsenoside Re via ingestion
def: "An exposure to ginsenoside Re via ingestion route." []
synonym: "ginsenoside Re exposure via ingestion route" EXACT []
is_a: ECTO:0900001 ! exposure to oral steroids
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:9002395 ! exposure to ginsenoside Re
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:77148 ! has exposure stimulus ginsenoside Re

[Term]
id: ECTO:0900068
name: exposure to angiogenesis inhibitor via injection
def: "An exposure to angiogenesis inhibitor via injection route." []
synonym: "angiogenesis inhibitor exposure via injection route" EXACT []
is_a: ECTO:9001815 ! exposure to angiogenesis inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:48422 ! has exposure stimulus angiogenesis inhibitor
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900069
name: exposure to Nivolumab via injection
def: "An exposure to Nivolumab via injection route." []
synonym: "Nivolumab exposure via injection route" EXACT []
is_a: ECTO:9002519 ! exposure to Nivolumab
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:231614 ! has exposure stimulus Nivolumab
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900070
name: exposure to antibacterial drug via ingestion
def: "An exposure to antibacterial drug via ingestion route." []
synonym: "antibacterial drug exposure via ingestion route" EXACT []
is_a: ECTO:0900197 ! exposure to antiinfective agent via ingestion
is_a: ECTO:9001757 ! exposure to antibacterial drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:36047 ! has exposure stimulus antibacterial drug

[Term]
id: ECTO:0900071
name: exposure to soyasaponin III(1-) via ingestion
def: "An exposure to soyasaponin III(1-) via ingestion route." []
synonym: "soyasaponin III(1-) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002339 ! exposure to soyasaponin III(1-)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:62911 ! has exposure stimulus soyasaponin III(1-)

[Term]
id: ECTO:0900072
name: exposure to calcium channel blocker via ingestion
def: "An exposure to calcium channel blocker via ingestion route." []
synonym: "calcium channel blocker exposure via ingestion route" EXACT []
is_a: ECTO:9001781 ! exposure to calcium channel blocker
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:38215 ! has exposure stimulus calcium channel blocker
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900073
name: exposure to celecoxib via ingestion
def: "An exposure to celecoxib via ingestion route." []
synonym: "celecoxib exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002278 ! exposure to celecoxib
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:41423 ! has exposure stimulus celecoxib

[Term]
id: ECTO:0900074
name: exposure to citalopram via ingestion
def: "An exposure to citalopram via ingestion route." []
synonym: "citalopram exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000660 ! exposure to citalopram
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:3723 ! has exposure stimulus citalopram

[Term]
id: ECTO:0900075
name: exposure to all-cis-5,8,11,14,17-icosapentaenoic acid via ingestion
def: "An exposure to all-cis-5,8,11,14,17-icosapentaenoic acid via ingestion route." []
synonym: "all-cis-5,8,11,14,17-icosapentaenoic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900052 ! exposure to omega-3 fatty acid via ingestion
is_a: ECTO:9002351 ! exposure to all-cis-5,8,11,14,17-icosapentaenoic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28364 ! has exposure stimulus all-cis-5,8,11,14,17-icosapentaenoic acid

[Term]
id: ECTO:0900076
name: exposure to gliadin via ingestion
def: "An exposure to gliadin via ingestion route." []
synonym: "gliadin exposure via ingestion route" EXACT []
is_a: ECTO:0900048 ! exposure to protein via ingestion
is_a: ECTO:9002396 ! exposure to gliadin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:190522 ! has exposure stimulus gliadin

[Term]
id: ECTO:0900078
name: exposure to macronutrient via ingestion
def: "An exposure to macronutrient via ingestion route." []
synonym: "macronutrient exposure via ingestion route" EXACT []
is_a: ECTO:0900056 ! exposure to nutrient via ingestion
is_a: ECTO:9001702 ! exposure to macronutrient
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33937 ! has exposure stimulus macronutrient

[Term]
id: ECTO:0900079
name: exposure to methionine via ingestion
def: "An exposure to methionine via ingestion route." []
synonym: "methionine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000498 ! exposure to methionine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16811 ! has exposure stimulus methionine

[Term]
id: ECTO:0900080
name: exposure to taurine via ingestion
def: "An exposure to taurine via ingestion route." []
synonym: "taurine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002625 ! exposure to taurine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15891 ! has exposure stimulus taurine

[Term]
id: ECTO:0900081
name: exposure to paclitaxel via injection
def: "An exposure to paclitaxel via injection route." []
synonym: "paclitaxel exposure via injection route" EXACT []
is_a: ECTO:9000388 ! exposure to paclitaxel
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:45863 ! has exposure stimulus paclitaxel
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900082
name: exposure to tenofovir disoproxil fumarate via ingestion
def: "An exposure to tenofovir disoproxil fumarate via ingestion route." []
synonym: "tenofovir disoproxil fumarate exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002630 ! exposure to tenofovir disoproxil fumarate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:63718 ! has exposure stimulus tenofovir disoproxil fumarate

[Term]
id: ECTO:0900083
name: exposure to ethanol via ingestion
def: "An exposure to ethanol via ingestion route." []
synonym: "ethanol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:9000027 ! exposure to ethanol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16236 ! has exposure stimulus ethanol

[Term]
id: ECTO:0900084
name: exposure to anthocyanin via ingestion
def: "An exposure to anthocyanin via ingestion route." []
synonym: "anthocyanin exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:9002857 ! exposure to anthocyanin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:38697 ! has exposure stimulus anthocyanin

[Term]
id: ECTO:0900085
name: exposure to flavonoid via ingestion
def: "An exposure to flavonoid via ingestion route." []
synonym: "flavonoid exposure via ingestion route" EXACT []
is_a: ECTO:0900133 ! exposure to flavonoids via ingestion
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:47916 ! has exposure stimulus flavonoid

[Term]
id: ECTO:0900086
name: exposure to fructooligosaccharide via ingestion
def: "An exposure to fructooligosaccharide via ingestion route." []
synonym: "fructooligosaccharide exposure via ingestion route" EXACT []
is_a: ECTO:0900320 ! exposure to oligosaccharide via ingestion
is_a: ECTO:9002379 ! exposure to fructooligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:190523 ! has exposure stimulus fructooligosaccharide

[Term]
id: ECTO:0900087
name: exposure to gut flora metabolite via ingestion
def: "An exposure to gut flora metabolite via ingestion route." []
synonym: "gut flora metabolite exposure via ingestion route" EXACT []
is_a: ECTO:9002410 ! exposure to gut flora metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:82933 ! has exposure stimulus gut flora metabolite
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900088
name: exposure to phosphorus via ingestion
def: "An exposure to phosphorus molecular entity via ingestion route." []
synonym: "phosphorus molecular entity exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26082 ! has exposure stimulus phosphorus molecular entity

[Term]
id: ECTO:0900089
name: exposure to beta-adrenergic agonist via inhalation
def: "An exposure to beta-adrenergic agonist via inhalation route." []
synonym: "beta-adrenergic agonist exposure via inhalation route" EXACT []
is_a: ECTO:9001730 ! exposure to beta-adrenergic agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:35522 ! has exposure stimulus beta-adrenergic agonist
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900090
name: exposure to nicotinamide via ingestion
def: "An exposure to nicotinamide via ingestion route." []
synonym: "nicotinamide exposure via ingestion route" EXACT []
is_a: ECTO:0900029 ! exposure to vitamin B via ingestion
is_a: ECTO:0900477 ! exposure to alkaloid via ingestion
is_a: ECTO:9002478 ! exposure to nicotinamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17154 ! has exposure stimulus nicotinamide

[Term]
id: ECTO:0900091
name: exposure to non-steroidal anti-inflammatory drug via ingestion
def: "An exposure to non-steroidal anti-inflammatory drug via ingestion route." []
synonym: "non-steroidal anti-inflammatory drug exposure via ingestion route" EXACT []
is_a: ECTO:9001720 ! exposure to non-steroidal anti-inflammatory drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35475 ! has exposure stimulus non-steroidal anti-inflammatory drug
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900092
name: exposure to polyphenol via ingestion
def: "An exposure to polyphenol via ingestion route." []
synonym: "polyphenol exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26195 ! has exposure stimulus polyphenol

[Term]
id: ECTO:0900093
name: exposure to polystyrene macromolecule via ingestion
def: "An exposure to polystyrene macromolecule via ingestion route." []
synonym: "polystyrene macromolecule exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002563 ! exposure to polystyrene macromolecule
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:53270 ! has exposure stimulus polystyrene macromolecule

[Term]
id: ECTO:0900094
name: exposure to serotonin uptake inhibitor via ingestion
def: "An exposure to serotonin uptake inhibitor via ingestion route." []
synonym: "serotonin uptake inhibitor exposure via ingestion route" EXACT []
is_a: ECTO:9001883 ! exposure to serotonin uptake inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50949 ! has exposure stimulus serotonin uptake inhibitor
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900095
name: exposure to sevoflurane via inhalation
def: "An exposure to sevoflurane via inhalation route." []
synonym: "sevoflurane exposure via inhalation route" EXACT []
is_a: ECTO:9002165 ! exposure to sevoflurane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:9130 ! has exposure stimulus sevoflurane
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900096
name: exposure to thiazide via ingestion
def: "An exposure to thiazide via ingestion route." []
synonym: "thiazide exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002635 ! exposure to thiazide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50264 ! has exposure stimulus thiazide

[Term]
id: ECTO:0900097
name: exposure to iodine via injection
def: "An exposure to iodine molecular entity via injection route." []
synonym: "iodine molecular entity exposure via injection route" EXACT []
is_a: ECTO:9000084 ! exposure to iodine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:24860 ! has exposure stimulus iodine molecular entity
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900098
name: exposure to 2-deoxy-D-glucose via injection
def: "An exposure to 2-deoxy-D-glucose via injection route." []
synonym: "2-deoxy-D-glucose exposure via injection route" EXACT []
is_a: ECTO:9002190 ! exposure to 2-deoxy-D-glucose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:15866 ! has exposure stimulus 2-deoxy-D-glucose
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900099
name: exposure to double-stranded RNA via injection
def: "An exposure to double-stranded RNA via injection route." []
synonym: "double-stranded RNA exposure via injection route" EXACT []
is_a: ECTO:9000272 ! exposure to double-stranded RNA
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:67208 ! has exposure stimulus double-stranded RNA
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900100
name: exposure to albuterol via inhalation
def: "An exposure to albuterol via inhalation route." []
synonym: "albuterol exposure via inhalation route" EXACT []
is_a: ECTO:9000565 ! exposure to albuterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:2549 ! has exposure stimulus albuterol
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900101
name: exposure to alcohol via ingestion
def: "An exposure to alcohol via ingestion route." []
synonym: "alcohol exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:30879 ! has exposure stimulus alcohol

[Term]
id: ECTO:0900102
name: exposure to azoxystrobin via ingestion
def: "An exposure to azoxystrobin via ingestion route." []
synonym: "azoxystrobin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000700 ! exposure to azoxystrobin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:40909 ! has exposure stimulus azoxystrobin

[Term]
id: ECTO:0900103
name: maternal exposure to androgen
def: "An exposure to androgen via maternal transfer." []
synonym: "androgen exposure via maternal" EXACT []
is_a: ECTO:9001833 ! exposure to androgen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:50113 ! has exposure stimulus androgen
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900104
name: exposure to angiotensin receptor antagonist via ingestion
def: "An exposure to angiotensin receptor antagonist via ingestion route." []
synonym: "angiotensin receptor antagonist exposure via ingestion route" EXACT []
is_a: ECTO:9001917 ! exposure to angiotensin receptor antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:61016 ! has exposure stimulus angiotensin receptor antagonist
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900105
name: exposure to rifampicin via ingestion
def: "An exposure to rifampicin via ingestion route." []
synonym: "rifampicin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002584 ! exposure to rifampicin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28077 ! has exposure stimulus rifampicin

[Term]
id: ECTO:0900106
name: exposure to antihypertensive agent via ingestion
def: "An exposure to antihypertensive agent via ingestion route." []
synonym: "antihypertensive agent exposure via ingestion route" EXACT []
is_a: ECTO:9001744 ! exposure to antihypertensive agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35674 ! has exposure stimulus antihypertensive agent
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900107
name: exposure to antithyroid drug via ingestion
def: "An exposure to antithyroid drug via ingestion route." []
synonym: "antithyroid drug exposure via ingestion route" EXACT []
is_a: ECTO:9001861 ! exposure to antithyroid drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50671 ! has exposure stimulus antithyroid drug
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900108
name: exposure to isoflurane via inhalation
def: "An exposure to isoflurane via inhalation route." []
synonym: "isoflurane exposure via inhalation route" EXACT []
is_a: ECTO:9002166 ! exposure to isoflurane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:6015 ! has exposure stimulus isoflurane
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900109
name: exposure to L-asparagine via injection
def: "An exposure to L-asparagine via injection route." []
synonym: "L-asparagine exposure via injection route" EXACT []
is_a: ECTO:9002764 ! exposure to L-asparagine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:17196 ! has exposure stimulus L-asparagine
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900110
name: exposure to astaxanthin via ingestion
def: "An exposure to astaxanthin via ingestion route." []
synonym: "astaxanthin exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002719 ! exposure to astaxanthin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:40968 ! has exposure stimulus astaxanthin

[Term]
id: ECTO:0900111
name: exposure to silibinin via ingestion
def: "An exposure to silibinin via ingestion route." []
synonym: "silibinin exposure via ingestion route" EXACT []
is_a: ECTO:0900092 ! exposure to polyphenol via ingestion
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900133 ! exposure to flavonoids via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002785 ! exposure to silibinin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:9144 ! has exposure stimulus silibinin

[Term]
id: ECTO:0900112
name: exposure to capsaicin via ingestion
def: "An exposure to capsaicin via ingestion route." []
synonym: "capsaicin exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002737 ! exposure to capsaicin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:3374 ! has exposure stimulus capsaicin

[Term]
id: ECTO:0900113
name: exposure to carbon monoxide via inhalation
def: "An exposure to carbon monoxide via inhalation route." []
synonym: "carbon monoxide exposure via inhalation route" EXACT []
is_a: ECTO:0000207 ! exposure to carbon monoxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:17245 ! has exposure stimulus carbon monoxide
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900114
name: exposure to icariin via ingestion
def: "An exposure to icariin via ingestion route." []
synonym: "icariin exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:9002811 ! exposure to icariin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:78420 ! has exposure stimulus icariin

[Term]
id: ECTO:0900115
name: exposure to chlorogenic acid via ingestion
def: "An exposure to chlorogenic acid via ingestion route." []
synonym: "chlorogenic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900092 ! exposure to polyphenol via ingestion
is_a: ECTO:9002747 ! exposure to chlorogenic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16112 ! has exposure stimulus chlorogenic acid

[Term]
id: ECTO:0900116
name: exposure to choline via ingestion
def: "An exposure to choline via ingestion route." []
synonym: "choline exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002749 ! exposure to choline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15354 ! has exposure stimulus choline

[Term]
id: ECTO:0900117
name: exposure to hispidulin via ingestion
def: "An exposure to hispidulin via ingestion route." []
synonym: "hispidulin exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:9002763 ! exposure to hispidulin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:75902 ! has exposure stimulus hispidulin

[Term]
id: ECTO:0900118
name: exposure to clopidogrel via ingestion
def: "An exposure to clopidogrel via ingestion route." []
synonym: "clopidogrel exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000440 ! exposure to clopidogrel
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:37941 ! has exposure stimulus clopidogrel

[Term]
id: ECTO:0900119
name: exposure to clozapine via ingestion
def: "An exposure to clozapine via ingestion route." []
synonym: "clozapine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000359 ! exposure to clozapine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:3766 ! has exposure stimulus clozapine

[Term]
id: ECTO:0900120
name: exposure to food component via ingestion
def: "An exposure to food component via ingestion route." []
synonym: "food component exposure via ingestion route" EXACT []
is_a: ECTO:9002063 ! exposure to food component
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:78295 ! has exposure stimulus food component
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900121
name: exposure to Interferon beta-1b via injection
def: "An exposure to Interferon beta-1b via injection route." []
synonym: "Interferon beta-1b exposure via injection route" EXACT []
is_a: ECTO:9002429 ! exposure to Interferon beta-1b
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:5938 ! has exposure stimulus Interferon beta-1b
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900122
name: exposure to quinoline via ingestion
def: "An exposure to quinoline via ingestion route." []
synonym: "quinoline exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9001245 ! exposure to quinoline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17362 ! has exposure stimulus quinoline

[Term]
id: ECTO:0900123
name: exposure to starch via ingestion
def: "An exposure to starch via ingestion route." []
synonym: "starch exposure via ingestion route" EXACT []
is_a: ECTO:0900055 ! exposure to polysaccharide via ingestion
is_a: ECTO:9002389 ! exposure to starch
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28017 ! has exposure stimulus starch

[Term]
id: ECTO:0900124
name: exposure to xenobiotic via ingestion
def: "An exposure to xenobiotic via ingestion route." []
synonym: "xenobiotic exposure via ingestion route" EXACT []
is_a: ECTO:9001746 ! exposure to xenobiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35703 ! has exposure stimulus xenobiotic
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900125
name: exposure to diuretic via ingestion
def: "An exposure to diuretic via ingestion route." []
synonym: "diuretic exposure via ingestion route" EXACT []
is_a: ECTO:9001728 ! exposure to diuretic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35498 ! has exposure stimulus diuretic
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900126
name: exposure to DDE via ingestion
def: "An exposure to DDE via ingestion route." []
synonym: "DDE exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000554 ! exposure to DDE
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16598 ! has exposure stimulus DDE

[Term]
id: ECTO:0900127
name: exposure to efavirenz via ingestion
def: "An exposure to efavirenz via ingestion route." []
synonym: "efavirenz exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002685 ! exposure to efavirenz
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:119486 ! has exposure stimulus efavirenz

[Term]
id: ECTO:0900128
name: exposure to phytotoxin via ingestion
def: "An exposure to phytotoxin via ingestion route." []
synonym: "phytotoxin exposure via ingestion route" EXACT []
is_a: ECTO:9001782 ! exposure to phytotoxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:38231 ! has exposure stimulus phytotoxin
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900129
name: exposure to escitalopram via ingestion
def: "An exposure to escitalopram via ingestion route." []
synonym: "escitalopram exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002780 ! exposure to escitalopram
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:36791 ! has exposure stimulus escitalopram

[Term]
id: ECTO:0900130
name: maternal exposure to estrogens
def: "An exposure to estrogens via maternal transfer." []
synonym: "estrogen exposure via maternal" EXACT []
is_a: ECTO:9000010 ! exposure to estrogens
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:50114 ! has exposure stimulus estrogen
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900131
name: exposure to fenofibrate via ingestion
def: "An exposure to fenofibrate via ingestion route." []
synonym: "fenofibrate exposure via ingestion route" EXACT []
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000390 ! exposure to fenofibrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:5001 ! has exposure stimulus fenofibrate

[Term]
id: ECTO:0900132
name: exposure to glycyrrhizinic acid via ingestion
def: "An exposure to glycyrrhizinic acid via ingestion route." []
synonym: "glycyrrhizinic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9002404 ! exposure to glycyrrhizinic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15939 ! has exposure stimulus glycyrrhizinic acid

[Term]
id: ECTO:0900133
name: exposure to flavonoids via ingestion
def: "An exposure to flavonoids via ingestion route." []
synonym: "flavonoids exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:72544 ! has exposure stimulus flavonoids

[Term]
id: ECTO:0900134
name: exposure to fructose via ingestion
def: "An exposure to fructose via ingestion route." []
synonym: "fructose exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9000166 ! exposure to fructose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28757 ! has exposure stimulus fructose

[Term]
id: ECTO:0900135
name: exposure to glipizide via ingestion
def: "An exposure to glipizide via ingestion route." []
synonym: "glipizide exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002397 ! exposure to glipizide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:5384 ! has exposure stimulus glipizide

[Term]
id: ECTO:0900136
name: exposure to thiamine via ingestion
def: "An exposure to vitamin B1 via ingestion route." []
synonym: "vitamin B1 exposure via ingestion route" EXACT []
is_a: ECTO:0900029 ! exposure to vitamin B via ingestion
is_a: ECTO:9000147 ! exposure to thiamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26948 ! has exposure stimulus vitamin B1

[Term]
id: ECTO:0900137
name: exposure to riboflavin via ingestion
def: "An exposure to riboflavin via ingestion route." []
synonym: "riboflavin exposure via ingestion route" EXACT []
is_a: ECTO:0900029 ! exposure to vitamin B via ingestion
is_a: ECTO:9000149 ! exposure to riboflavin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17015 ! has exposure stimulus riboflavin

[Term]
id: ECTO:0900139
name: exposure to dioxygen via inhalation
def: "An exposure to dioxygen via inhalation route." []
synonym: "dioxygen exposure via inhalation route" EXACT []
is_a: ECTO:9000519 ! exposure to dioxygen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:15379 ! has exposure stimulus dioxygen
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900140
name: exposure to L-arginine, methyl ester via ingestion
def: "An exposure to L-arginine, methyl ester via ingestion route." []
synonym: "L-arginine, methyl ester exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002688 ! exposure to L-arginine, methyl ester
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:184062 ! has exposure stimulus L-arginine, methyl ester

[Term]
id: ECTO:0900141
name: exposure to lactose via ingestion
def: "An exposure to lactose via ingestion route." []
synonym: "lactose exposure via ingestion route" EXACT []
is_a: ECTO:0900320 ! exposure to oligosaccharide via ingestion
is_a: ECTO:9002451 ! exposure to lactose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17716 ! has exposure stimulus lactose

[Term]
id: ECTO:0900142
name: exposure to lipopolysaccharide via inhalation
def: "An exposure to lipopolysaccharide via inhalation route." []
synonym: "lipopolysaccharide exposure via inhalation route" EXACT []
is_a: ECTO:9000215 ! exposure to lipopolysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:16412 ! has exposure stimulus lipopolysaccharide
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900143
name: exposure to maltose via ingestion
def: "An exposure to maltose via ingestion route." []
synonym: "maltose exposure via ingestion route" EXACT []
is_a: ECTO:0900320 ! exposure to oligosaccharide via ingestion
is_a: ECTO:9000241 ! exposure to maltose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17306 ! has exposure stimulus maltose

[Term]
id: ECTO:0900144
name: exposure to metformin via ingestion
def: "An exposure to metformin via ingestion route." []
synonym: "metformin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000391 ! exposure to metformin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:6801 ! has exposure stimulus metformin

[Term]
id: ECTO:0900145
name: maternal exposure to Mitoquinone
def: "An exposure to Mitoquinone via maternal transfer." []
synonym: "Mitoquinone exposure via maternal" EXACT []
is_a: ECTO:9002495 ! exposure to Mitoquinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:233321 ! has exposure stimulus Mitoquinone
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900146
name: exposure to N-carbamoylglutamate(2-) via ingestion
def: "An exposure to N-carbamoylglutamate(2-) via ingestion route." []
synonym: "N-carbamoylglutamate(2-) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002509 ! exposure to N-carbamoylglutamate(2-)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:233559 ! has exposure stimulus N-carbamoylglutamate(2-)

[Term]
id: ECTO:0900147
name: exposure to nicotine via ingestion
def: "An exposure to nicotine via ingestion route." []
synonym: "nicotine exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000250 ! exposure to nicotine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18723 ! has exposure stimulus nicotine

[Term]
id: ECTO:0900148
name: exposure to nitrogen dioxide via inhalation
def: "An exposure to nitrogen dioxide via inhalation route." []
synonym: "nitrogen dioxide exposure via inhalation route" EXACT []
is_a: ECTO:9000252 ! exposure to nitrogen dioxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:33101 ! has exposure stimulus nitrogen dioxide
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900149
name: exposure to obeticholic acid via ingestion
def: "An exposure to obeticholic acid via ingestion route." []
synonym: "obeticholic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900219 ! exposure to bile acid via ingestion
is_a: ECTO:9002524 ! exposure to obeticholic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:43602 ! has exposure stimulus obeticholic acid

[Term]
id: ECTO:0900150
name: exposure to olanzapine via ingestion
def: "An exposure to olanzapine via ingestion route." []
synonym: "olanzapine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000354 ! exposure to olanzapine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:7735 ! has exposure stimulus olanzapine

[Term]
id: ECTO:0900151
name: exposure to essential oil via ingestion
def: "An exposure to essential oil via ingestion route." []
synonym: "essential oil exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002292 ! exposure to essential oil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:83630 ! has exposure stimulus essential oil

[Term]
id: ECTO:0900152
name: exposure to oxaliplatin via injection
def: "An exposure to oxaliplatin via injection route." []
synonym: "oxaliplatin exposure via injection route" EXACT []
is_a: ECTO:0900156 ! exposure to platinum via injection
is_a: ECTO:9002530 ! exposure to oxaliplatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:31941 ! has exposure stimulus oxaliplatin

[Term]
id: ECTO:0900153
name: exposure to ozone via inhalation
def: "An exposure to ozone via inhalation route." []
synonym: "ozone exposure via inhalation route" EXACT []
is_a: ECTO:9000052 ! exposure to ozone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:25812 ! has exposure stimulus ozone
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900154
name: exposure to perfluorohexanesulfonic acid via ingestion
def: "An exposure to perfluorohexanesulfonic acid via ingestion route." []
synonym: "perfluorohexanesulfonic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001623 ! exposure to perfluorohexanesulfonic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:132448 ! has exposure stimulus perfluorohexanesulfonic acid

[Term]
id: ECTO:0900155
name: exposure to perfluorononanoic acid via ingestion
def: "An exposure to perfluorononanoic acid via ingestion route." []
synonym: "perfluorononanoic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000669 ! exposure to perfluorononanoic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:38397 ! has exposure stimulus perfluorononanoic acid

[Term]
id: ECTO:0900156
name: exposure to platinum via injection
def: "An exposure to platinum molecular entity via injection route." []
synonym: "platinum molecular entity exposure via injection route" EXACT []
is_a: ECTO:9000949 ! exposure to platinum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:33749 ! has exposure stimulus platinum molecular entity
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900157
name: exposure to polyethylene polymer via ingestion
def: "An exposure to polyethylene polymer via ingestion route." []
synonym: "polyethylene polymer exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000115 ! exposure to polyethylene polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:60034 ! has exposure stimulus polyethylene polymer

[Term]
id: ECTO:0900158
name: exposure to pravastatin via ingestion
def: "An exposure to pravastatin via ingestion route." []
synonym: "pravastatin exposure via ingestion route" EXACT []
is_a: ECTO:0900064 ! exposure to statin via ingestion
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000753 ! exposure to pravastatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:63618 ! has exposure stimulus pravastatin

[Term]
id: ECTO:0900159
name: exposure to glycerol via inhalation
def: "An exposure to glycerol via inhalation route." []
synonym: "glycerol exposure via inhalation route" EXACT []
is_a: ECTO:9001576 ! exposure to glycerol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:17754 ! has exposure stimulus glycerol
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900160
name: exposure to simvastatin via ingestion
def: "An exposure to simvastatin via ingestion route." []
synonym: "simvastatin exposure via ingestion route" EXACT []
is_a: ECTO:0900064 ! exposure to statin via ingestion
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000438 ! exposure to simvastatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:9150 ! has exposure stimulus simvastatin

[Term]
id: ECTO:0900161
name: exposure to titanium dioxide nanoparticle via inhalation
def: "An exposure to titanium dioxide nanoparticle via inhalation route." []
synonym: "titanium dioxide nanoparticle exposure via inhalation route" EXACT []
is_a: ECTO:9001369 ! exposure to titanium dioxide nanoparticle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:51050 ! has exposure stimulus titanium dioxide nanoparticle
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900162
name: exposure to valproate semisodium via ingestion
def: "An exposure to valproate semisodium via ingestion route." []
synonym: "valproate semisodium exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002239 ! exposure to valproate semisodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:4667 ! has exposure stimulus valproate semisodium

[Term]
id: ECTO:0900163
name: exposure to venlafaxine via ingestion
def: "An exposure to venlafaxine via ingestion route." []
synonym: "venlafaxine exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000904 ! exposure to venlafaxine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:9943 ! has exposure stimulus venlafaxine

[Term]
id: ECTO:0900164
name: exposure to beta-ocimene via inhalation
def: "An exposure to beta-ocimene via inhalation route." []
synonym: "beta-ocimene exposure via inhalation route" EXACT []
is_a: ECTO:9002671 ! exposure to beta-ocimene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:10436 ! has exposure stimulus beta-ocimene
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900165
name: exposure to dicyclohexylmethane-4,4'-diisocyanate via ingestion
def: "An exposure to dicyclohexylmethane-4,4'-diisocyanate via ingestion route." []
synonym: "dicyclohexylmethane-4,4'-diisocyanate exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9001586 ! exposure to dicyclohexylmethane-4,4'-diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:53216 ! has exposure stimulus dicyclohexylmethane-4,4'-diisocyanate

[Term]
id: ECTO:0900166
name: exposure to buta-1,3-diene via inhalation
def: "An exposure to buta-1,3-diene via inhalation route." []
synonym: "buta-1,3-diene exposure via inhalation route" EXACT []
is_a: ECTO:9001003 ! exposure to buta-1,3-diene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:39478 ! has exposure stimulus buta-1,3-diene
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900167
name: exposure to 1,4-Methylimidazoleacetic acid via ingestion
def: "An exposure to 1,4-Methylimidazoleacetic acid via ingestion route." []
synonym: "1,4-Methylimidazoleacetic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002673 ! exposure to 1,4-Methylimidazoleacetic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:185646 ! has exposure stimulus 1,4-Methylimidazoleacetic acid

[Term]
id: ECTO:0900168
name: exposure to diterpene via ingestion
def: "An exposure to diterpene via ingestion route." []
synonym: "diterpene exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000494 ! exposure to diterpene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35190 ! has exposure stimulus diterpene

[Term]
id: ECTO:0900169
name: exposure to 17beta-estradiol via injection
def: "An exposure to 17beta-estradiol via injection route." []
synonym: "17beta-estradiol exposure via injection route" EXACT []
is_a: ECTO:0900287 ! exposure to estradiol via injection
is_a: ECTO:9002670 ! exposure to 17beta-estradiol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:16469 ! has exposure stimulus 17beta-estradiol

[Term]
id: ECTO:0900170
name: exposure to 4-Heptanone via inhalation
def: "An exposure to 4-heptanone via inhalation route." []
synonym: "4-heptanone exposure via inhalation route" EXACT []
is_a: ECTO:9001567 ! exposure to 4-Heptanone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:89484 ! has exposure stimulus 4-heptanone
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900171
name: exposure to 2-hydroxy-3-methylbutyrate via ingestion
def: "An exposure to 2-hydroxy-3-methylbutyrate via ingestion route." []
synonym: "2-hydroxy-3-methylbutyrate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002191 ! exposure to 2-hydroxy-3-methylbutyrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:64669 ! has exposure stimulus 2-hydroxy-3-methylbutyrate

[Term]
id: ECTO:0900172
name: exposure to 24-hydroxycholesterol via injection
def: "An exposure to 24-hydroxycholesterol via injection route." []
synonym: "24-hydroxycholesterol exposure via injection route" EXACT []
is_a: ECTO:9002786 ! exposure to 24-hydroxycholesterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:50515 ! has exposure stimulus 24-hydroxycholesterol
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900173
name: exposure to isophthalonitrile via injection
def: "An exposure to isophthalonitrile via injection route." []
synonym: "isophthalonitrile exposure via injection route" EXACT []
is_a: ECTO:9001597 ! exposure to isophthalonitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:38218 ! has exposure stimulus isophthalonitrile
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900174
name: exposure to 3,5,6-trichloro-2-pyridinol via ingestion
def: "An exposure to 3,5,6-trichloro-2-pyridinol via ingestion route." []
synonym: "3,5,6-trichloro-2-pyridinol exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002196 ! exposure to 3,5,6-trichloro-2-pyridinol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:143794 ! has exposure stimulus 3,5,6-trichloro-2-pyridinol

[Term]
id: ECTO:0900175
name: exposure to 3-phenylpropionic acid via ingestion
def: "An exposure to 3-phenylpropionic acid via ingestion route." []
synonym: "3-phenylpropionic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002200 ! exposure to 3-phenylpropionic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28631 ! has exposure stimulus 3-phenylpropionic acid

[Term]
id: ECTO:0900176
name: exposure to 4-guanidinobutyric acid via ingestion
def: "An exposure to 4-guanidinobutyric acid via ingestion route." []
synonym: "4-guanidinobutyric acid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002202 ! exposure to 4-guanidinobutyric acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:86564 ! has exposure stimulus 4-guanidinobutyric acid

[Term]
id: ECTO:0900177
name: exposure to 5-aminolevulinic acid via ingestion
def: "An exposure to 5-aminolevulinic acid via ingestion route." []
synonym: "5-aminolevulinic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002207 ! exposure to 5-aminolevulinic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17549 ! has exposure stimulus 5-aminolevulinic acid

[Term]
id: ECTO:0900178
name: exposure to 2-deoxy-D-glucose via ingestion
def: "An exposure to 2-deoxy-D-glucose via ingestion route." []
synonym: "2-deoxy-D-glucose exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9002190 ! exposure to 2-deoxy-D-glucose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15866 ! has exposure stimulus 2-deoxy-D-glucose

[Term]
id: ECTO:0900179
name: exposure to GW405833 via ingestion
def: "An exposure to GW405833 via ingestion route." []
synonym: "GW405833 exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002304 ! exposure to GW405833
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:92184 ! has exposure stimulus GW405833

[Term]
id: ECTO:0900180
name: exposure to glycoprotein via ingestion
def: "An exposure to glycoprotein via ingestion route." []
synonym: "glycoprotein exposure via ingestion route" EXACT []
is_a: ECTO:0900048 ! exposure to protein via ingestion
is_a: ECTO:9000487 ! exposure to glycoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17089 ! has exposure stimulus glycoprotein

[Term]
id: ECTO:0900181
name: exposure to abacavir via ingestion
def: "An exposure to abacavir via ingestion route." []
synonym: "abacavir exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002214 ! exposure to abacavir
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:421707 ! has exposure stimulus abacavir

[Term]
id: ECTO:0900182
name: exposure to abiraterone acetate via ingestion
def: "An exposure to abiraterone acetate via ingestion route." []
synonym: "abiraterone acetate exposure via ingestion route" EXACT []
is_a: ECTO:0900001 ! exposure to oral steroids
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002215 ! exposure to abiraterone acetate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:68639 ! has exposure stimulus abiraterone acetate

[Term]
id: ECTO:0900183
name: exposure to acetate via ingestion
def: "An exposure to acetate via ingestion route." []
synonym: "acetate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000171 ! exposure to acetate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:30089 ! has exposure stimulus acetate

[Term]
id: ECTO:0900184
name: exposure to acetic acid via ingestion
def: "An exposure to acetic acid via ingestion route." []
synonym: "acetic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000019 ! exposure to acetic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15366 ! has exposure stimulus acetic acid

[Term]
id: ECTO:0900185
name: exposure to strontium(2+) via ingestion
def: "An exposure to strontium(2+) via ingestion route." []
synonym: "strontium(2+) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002615 ! exposure to strontium(2+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35104 ! has exposure stimulus strontium(2+)

[Term]
id: ECTO:0900186
name: exposure to acrolein via inhalation
def: "An exposure to acrolein via inhalation route." []
synonym: "acrolein exposure via inhalation route" EXACT []
is_a: ECTO:9000964 ! exposure to acrolein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:15368 ! has exposure stimulus acrolein
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900187
name: exposure to acrylamide via injection
def: "An exposure to acrylamide via injection route." []
synonym: "acrylamide exposure via injection route" EXACT []
is_a: ECTO:9000451 ! exposure to acrylamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:28619 ! has exposure stimulus acrylamide
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900188
name: exposure to adenine via ingestion
def: "An exposure to adenine via ingestion route." []
synonym: "adenine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002220 ! exposure to adenine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16708 ! has exposure stimulus adenine

[Term]
id: ECTO:0900189
name: exposure to neotame via ingestion
def: "An exposure to neotame via ingestion route." []
synonym: "neotame exposure via ingestion route" EXACT []
is_a: ECTO:0900059 ! exposure to peptide via ingestion
is_a: ECTO:9000857 ! exposure to neotame
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:83503 ! has exposure stimulus neotame

[Term]
id: ECTO:0900190
name: exposure to angiotensin receptor antagonist via inhalation
def: "An exposure to angiotensin receptor antagonist via inhalation route." []
synonym: "angiotensin receptor antagonist exposure via inhalation route" EXACT []
is_a: ECTO:9001917 ! exposure to angiotensin receptor antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:61016 ! has exposure stimulus angiotensin receptor antagonist
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900191
name: maternal exposure to aluminum
def: "An exposure to aluminum via maternal transfer." []
synonym: "aluminium molecular entity exposure via maternal" EXACT []
is_a: ECTO:9000029 ! exposure to aluminum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:33620 ! has exposure stimulus aluminium molecular entity
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900192
name: exposure to aluminum via ingestion
def: "An exposure to aluminium molecular entity via ingestion route." []
synonym: "aluminium molecular entity exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000029 ! exposure to aluminum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33620 ! has exposure stimulus aluminium molecular entity

[Term]
id: ECTO:0900193
name: exposure to amlodipine via ingestion
def: "An exposure to amlodipine via ingestion route." []
synonym: "amlodipine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000001 ! exposure to amlodipine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:2668 ! has exposure stimulus amlodipine

[Term]
id: ECTO:0900194
name: exposure to amylopectin via ingestion
def: "An exposure to amylopectin via ingestion route." []
synonym: "amylopectin exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000275 ! exposure to amylopectin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28057 ! has exposure stimulus amylopectin

[Term]
id: ECTO:0900195
name: exposure to isoamyl acetate via inhalation
def: "An exposure to isoamyl acetate via inhalation route." []
synonym: "isoamyl acetate exposure via inhalation route" EXACT []
is_a: ECTO:9001458 ! exposure to isoamyl acetate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:31725 ! has exposure stimulus isoamyl acetate
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900196
name: exposure to pheromone via inhalation
def: "An exposure to pheromone via inhalation route." []
synonym: "pheromone exposure via inhalation route" EXACT []
is_a: ECTO:9001680 ! exposure to pheromone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:26013 ! has exposure stimulus pheromone
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900197
name: exposure to antiinfective agent via ingestion
def: "An exposure to antiinfective agent via ingestion route." []
synonym: "antiinfective agent exposure via ingestion route" EXACT []
is_a: ECTO:9001711 ! exposure to antiinfective agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35441 ! has exposure stimulus antiinfective agent
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900198
name: maternal exposure to double-stranded DNA
def: "An exposure to double-stranded DNA via maternal transfer." []
synonym: "double-stranded DNA exposure via maternal" EXACT []
is_a: ECTO:9000518 ! exposure to double-stranded DNA
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:4705 ! has exposure stimulus double-stranded DNA
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900199
name: exposure to antibiotic pesticide via ingestion
def: "An exposure to antibiotic pesticide via ingestion route." []
synonym: "antibiotic pesticide exposure via ingestion route" EXACT []
is_a: ECTO:0900419 ! exposure to pesticide via ingestion
is_a: ECTO:9002108 ! exposure to antibiotic pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:39215 ! has exposure stimulus antibiotic pesticide

[Term]
id: ECTO:0900200
name: exposure to antioxidant via ingestion
def: "An exposure to antioxidant via ingestion route." []
synonym: "antioxidant exposure via ingestion route" EXACT []
is_a: ECTO:9001647 ! exposure to antioxidant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22586 ! has exposure stimulus antioxidant
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900201
name: exposure to sodium channel blocker via ingestion
def: "An exposure to sodium channel blocker via ingestion route." []
synonym: "sodium channel blocker exposure via ingestion route" EXACT []
is_a: ECTO:9001787 ! exposure to sodium channel blocker
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:38633 ! has exposure stimulus sodium channel blocker
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900202
name: exposure to apixaban via ingestion
def: "An exposure to apixaban via ingestion route." []
synonym: "apixaban exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002715 ! exposure to apixaban
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:72296 ! has exposure stimulus apixaban

[Term]
id: ECTO:0900203
name: exposure to plant activator via ingestion
def: "An exposure to plant activator via ingestion route." []
synonym: "plant activator exposure via ingestion route" EXACT []
is_a: ECTO:9002011 ! exposure to plant activator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:73182 ! has exposure stimulus plant activator
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900204
name: exposure to arabinose via ingestion
def: "An exposure to arabinose via ingestion route." []
synonym: "arabinose exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9002768 ! exposure to arabinose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22599 ! has exposure stimulus arabinose

[Term]
id: ECTO:0900205
name: exposure to Arctiin via ingestion
def: "An exposure to Arctiin via ingestion route." []
synonym: "Arctiin exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002716 ! exposure to Arctiin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:80793 ! has exposure stimulus Arctiin

[Term]
id: ECTO:0900206
name: exposure to aripiprazole via ingestion
def: "An exposure to aripiprazole via ingestion route." []
synonym: "aripiprazole exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002243 ! exposure to aripiprazole
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:31236 ! has exposure stimulus aripiprazole

[Term]
id: ECTO:0900207
name: exposure to arsenic(3+) via ingestion
def: "An exposure to arsenic(3+) via ingestion route." []
synonym: "arsenic(3+) exposure via ingestion route" EXACT []
is_a: ECTO:0900004 ! exposure to arsenic via ingestion
is_a: ECTO:9002674 ! exposure to arsenic(3+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35828 ! has exposure stimulus arsenic(3+)

[Term]
id: ECTO:0900208
name: exposure to asbestos via inhalation
def: "An exposure to asbestos via inhalation route." []
synonym: "asbestos exposure via inhalation route" EXACT []
is_a: ECTO:9000033 ! exposure to asbestos
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:46661 ! has exposure stimulus asbestos
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900209
name: exposure to asparagine via ingestion
def: "An exposure to asparagine via ingestion route." []
synonym: "asparagine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002717 ! exposure to asparagine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22653 ! has exposure stimulus asparagine

[Term]
id: ECTO:0900210
name: exposure to atazanavir via ingestion
def: "An exposure to atazanavir via ingestion route." []
synonym: "atazanavir exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002720 ! exposure to atazanavir
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:37924 ! has exposure stimulus atazanavir

[Term]
id: ECTO:0900211
name: exposure to atenolol via ingestion
def: "An exposure to atenolol via ingestion route." []
synonym: "atenolol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000581 ! exposure to atenolol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:2904 ! has exposure stimulus atenolol

[Term]
id: ECTO:0900212
name: exposure to ammonia via inhalation
def: "An exposure to ammonia via inhalation route." []
synonym: "ammonia exposure via inhalation route" EXACT []
is_a: ECTO:9000031 ! exposure to ammonia
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:16134 ! has exposure stimulus ammonia
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900213
name: exposure to atorvastatin via ingestion
def: "An exposure to atorvastatin via ingestion route." []
synonym: "atorvastatin exposure via ingestion route" EXACT []
is_a: ECTO:0900064 ! exposure to statin via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000696 ! exposure to atorvastatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:39548 ! has exposure stimulus atorvastatin

[Term]
id: ECTO:0900214
name: exposure to Amphotericin B via ingestion
def: "An exposure to amphotericin B via ingestion route." []
synonym: "amphotericin B exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002234 ! exposure to Amphotericin B
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:2682 ! has exposure stimulus amphotericin B

[Term]
id: ECTO:0900215
name: exposure to melittin via injection
def: "An exposure to melittin via injection route." []
synonym: "melittin exposure via injection route" EXACT []
is_a: ECTO:0900469 ! exposure to peptide via injection
is_a: ECTO:9002829 ! exposure to melittin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:6736 ! has exposure stimulus melittin

[Term]
id: ECTO:0900216
name: exposure to benzene via inhalation
def: "An exposure to benzene via inhalation route." []
synonym: "benzene exposure via inhalation route" EXACT []
is_a: ECTO:9000034 ! exposure to benzene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:16716 ! has exposure stimulus benzene
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900217
name: exposure to benzene via ingestion
def: "An exposure to benzene via ingestion route." []
synonym: "benzene exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000034 ! exposure to benzene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16716 ! has exposure stimulus benzene

[Term]
id: ECTO:0900218
name: exposure to berberine via ingestion
def: "An exposure to berberine via ingestion route." []
synonym: "berberine exposure via ingestion route" EXACT []
is_a: ECTO:0900477 ! exposure to alkaloid via ingestion
is_a: ECTO:9002259 ! exposure to berberine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16118 ! has exposure stimulus berberine

[Term]
id: ECTO:0900219
name: exposure to bile acid via ingestion
def: "An exposure to bile acid via ingestion route." []
synonym: "bile acid exposure via ingestion route" EXACT []
is_a: ECTO:0900058 ! exposure to bile acids via ingestion
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:3098 ! has exposure stimulus bile acid

[Term]
id: ECTO:0900220
name: exposure to bisphenol F via ingestion
def: "An exposure to bisphenol F via ingestion route." []
synonym: "bisphenol F exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002260 ! exposure to bisphenol F
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:34575 ! has exposure stimulus bisphenol F

[Term]
id: ECTO:0900221
name: maternal exposure to bisphenol A
def: "An exposure to bisphenol A via maternal transfer." []
synonym: "bisphenol A exposure via maternal" EXACT []
is_a: ECTO:9000057 ! exposure to bisphenol A
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:33216 ! has exposure stimulus bisphenol A
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900222
name: exposure to bleomycin via injection
def: "An exposure to bleomycin via injection route." []
synonym: "bleomycin exposure via injection route" EXACT []
is_a: ECTO:0900469 ! exposure to peptide via injection
is_a: ECTO:9000510 ! exposure to bleomycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:22907 ! has exposure stimulus bleomycin

[Term]
id: ECTO:0900223
name: exposure to Brilliant Blue via ingestion
def: "An exposure to Brilliant Blue via ingestion route." []
synonym: "Brilliant Blue exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002731 ! exposure to Brilliant Blue
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:82411 ! has exposure stimulus Brilliant Blue

[Term]
id: ECTO:0900224
name: exposure to bromoform via inhalation
def: "An exposure to bromoform via inhalation route." []
synonym: "bromoform exposure via inhalation route" EXACT []
is_a: ECTO:9001000 ! exposure to bromoform
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:38682 ! has exposure stimulus bromoform
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900225
name: exposure to busulfan via injection
def: "An exposure to busulfan via injection route." []
synonym: "busulfan exposure via injection route" EXACT []
is_a: ECTO:9002734 ! exposure to busulfan
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:28901 ! has exposure stimulus busulfan
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900226
name: exposure to butyrate via ingestion
def: "An exposure to butyrate via ingestion route." []
synonym: "butyrate exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000443 ! exposure to butyrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17968 ! has exposure stimulus butyrate

[Term]
id: ECTO:0900227
name: exposure to cadmium(2+) via ingestion
def: "An exposure to cadmium(2+) via ingestion route." []
synonym: "cadmium(2+) exposure via ingestion route" EXACT []
is_a: ECTO:0900017 ! exposure to cadmium cation via ingestion
is_a: ECTO:9002267 ! exposure to cadmium(2+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:48775 ! has exposure stimulus cadmium(2+)

[Term]
id: ECTO:0900228
name: exposure to candesartan via ingestion
def: "An exposure to candesartan via ingestion route." []
synonym: "candesartan exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000389 ! exposure to candesartan
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:3347 ! has exposure stimulus candesartan

[Term]
id: ECTO:0900229
name: exposure to capecitabine via ingestion
def: "An exposure to capecitabine via ingestion route." []
synonym: "capecitabine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002270 ! exposure to capecitabine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:31348 ! has exposure stimulus capecitabine

[Term]
id: ECTO:0900230
name: exposure to methimazole via ingestion
def: "An exposure to methimazole via ingestion route." []
synonym: "methimazole exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002488 ! exposure to methimazole
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50673 ! has exposure stimulus methimazole

[Term]
id: ECTO:0900231
name: exposure to tetrachloromethane via injection
def: "An exposure to tetrachloromethane via injection route." []
synonym: "tetrachloromethane exposure via injection route" EXACT []
is_a: ECTO:9000048 ! exposure to tetrachloromethane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:27385 ! has exposure stimulus tetrachloromethane
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900232
name: exposure to carboplatin via injection
def: "An exposure to carboplatin via injection route." []
synonym: "carboplatin exposure via injection route" EXACT []
is_a: ECTO:0900156 ! exposure to platinum via injection
is_a: ECTO:9000351 ! exposure to carboplatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:31355 ! has exposure stimulus carboplatin

[Term]
id: ECTO:0900233
name: exposure to catalpol via ingestion
def: "An exposure to catalpol via ingestion route." []
synonym: "catalpol exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002739 ! exposure to catalpol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:69797 ! has exposure stimulus catalpol

[Term]
id: ECTO:0900234
name: exposure to cellobiose via ingestion
def: "An exposure to cellobiose via ingestion route." []
synonym: "cellobiose exposure via ingestion route" EXACT []
is_a: ECTO:0900320 ! exposure to oligosaccharide via ingestion
is_a: ECTO:9002279 ! exposure to cellobiose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17057 ! has exposure stimulus cellobiose

[Term]
id: ECTO:0900235
name: exposure to ceruletide via injection
def: "An exposure to ceruletide via injection route." []
synonym: "ceruletide exposure via injection route" EXACT []
is_a: ECTO:0900469 ! exposure to peptide via injection
is_a: ECTO:9002736 ! exposure to ceruletide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:59219 ! has exposure stimulus ceruletide

[Term]
id: ECTO:0900236
name: exposure to colibactin via ingestion
def: "An exposure to colibactin via ingestion route." []
synonym: "colibactin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002301 ! exposure to colibactin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:156303 ! has exposure stimulus colibactin

[Term]
id: ECTO:0900237
name: exposure to cholesterol in food via ingestion
def: "An exposure to cholesterol via ingestion route." []
synonym: "cholesterol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900425 ! exposure to sterol via ingestion
is_a: ECTO:9000310 ! exposure to cholesterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16113 ! has exposure stimulus cholesterol

[Term]
id: ECTO:0900238
name: exposure to propionate via ingestion
def: "An exposure to propionate via ingestion route." []
synonym: "propionate exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002570 ! exposure to propionate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17272 ! has exposure stimulus propionate

[Term]
id: ECTO:0900239
name: exposure to chromium(3+) via ingestion
def: "An exposure to chromium(3+) via ingestion route." []
synonym: "chromium(3+) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002289 ! exposure to chromium(3+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:49544 ! has exposure stimulus chromium(3+)

[Term]
id: ECTO:0900240
name: exposure to cortisol via ingestion
def: "An exposure to cortisol via ingestion route." []
synonym: "cortisol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900323 ! exposure to corticosteroid via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000297 ! exposure to cortisol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17650 ! has exposure stimulus cortisol

[Term]
id: ECTO:0900241
name: exposure to cisplatin via ingestion
def: "An exposure to cisplatin via ingestion route." []
synonym: "cisplatin exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000330 ! exposure to cisplatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27899 ! has exposure stimulus cisplatin

[Term]
id: ECTO:0900242
name: exposure to citric acid via ingestion
def: "An exposure to citric acid via ingestion route." []
synonym: "citric acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002294 ! exposure to citric acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:30769 ! has exposure stimulus citric acid

[Term]
id: ECTO:0900243
name: exposure to colchicine via ingestion
def: "An exposure to colchicine via ingestion route." []
synonym: "colchicine exposure via ingestion route" EXACT []
is_a: ECTO:0900477 ! exposure to alkaloid via ingestion
is_a: ECTO:9002300 ! exposure to colchicine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:23359 ! has exposure stimulus colchicine

[Term]
id: ECTO:0900244
name: exposure to antitussive via ingestion
def: "An exposure to antitussive via ingestion route." []
synonym: "antitussive exposure via ingestion route" EXACT []
is_a: ECTO:9001885 ! exposure to antitussive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:51177 ! has exposure stimulus antitussive
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900245
name: exposure to Collagen via injection
def: "An exposure to Collagen via injection route." []
synonym: "Collagen exposure via injection route" EXACT []
is_a: ECTO:9002753 ! exposure to Collagen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:3815 ! has exposure stimulus Collagen
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900246
name: exposure to EC 3.4.24.3 (microbial collagenase) inhibitor via injection
def: "An exposure to EC 3.4.24.3 (microbial collagenase) inhibitor via injection route." []
synonym: "EC 3.4.24.3 (microbial collagenase) inhibitor exposure via injection route" EXACT []
is_a: ECTO:9001984 ! exposure to EC 3.4.24.3 (microbial collagenase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:67189 ! has exposure stimulus EC 3.4.24.3 (microbial collagenase) inhibitor
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900247
name: maternal exposure to copper cation
def: "An exposure to copper cation via maternal transfer." []
synonym: "copper cation exposure via maternal" EXACT []
is_a: ECTO:9000288 ! exposure to copper cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:23378 ! has exposure stimulus copper cation
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900248
name: exposure to copper(2+) via ingestion
def: "An exposure to copper(2+) via ingestion route." []
synonym: "copper(2+) exposure via ingestion route" EXACT []
is_a: ECTO:0900249 ! exposure to copper via ingestion
is_a: ECTO:9001531 ! exposure to copper(2+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:29036 ! has exposure stimulus copper(2+)

[Term]
id: ECTO:0900249
name: exposure to copper via ingestion
def: "An exposure to copper molecular entity via ingestion route." []
synonym: "copper molecular entity exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000944 ! exposure to copper
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:23377 ! has exposure stimulus copper molecular entity

[Term]
id: ECTO:0900250
name: exposure to corticosteroid via inhalation
def: "An exposure to corticosteroid via inhalation route." []
synonym: "corticosteroid exposure via inhalation route" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:50858 ! has exposure stimulus corticosteroid
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900251
name: exposure to crotonaldehyde via inhalation
def: "An exposure to crotonaldehyde via inhalation route." []
synonym: "crotonaldehyde exposure via inhalation route" EXACT []
is_a: ECTO:9001048 ! exposure to crotonaldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:41607 ! has exposure stimulus crotonaldehyde
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900252
name: exposure to crystalline cellulose via ingestion
def: "An exposure to crystalline cellulose via ingestion route." []
synonym: "crystalline cellulose exposure via ingestion route" EXACT []
is_a: ECTO:0900055 ! exposure to polysaccharide via ingestion
is_a: ECTO:9002756 ! exposure to crystalline cellulose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:62968 ! has exposure stimulus crystalline cellulose

[Term]
id: ECTO:0900253
name: exposure to curcumin via ingestion
def: "An exposure to curcumin via ingestion route." []
synonym: "curcumin exposure via ingestion route" EXACT []
is_a: ECTO:0900092 ! exposure to polyphenol via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000500 ! exposure to curcumin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:3962 ! has exposure stimulus curcumin

[Term]
id: ECTO:0900254
name: exposure to cyclophosphamide via ingestion
def: "An exposure to cyclophosphamide via ingestion route." []
synonym: "cyclophosphamide exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000417 ! exposure to cyclophosphamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:4027 ! has exposure stimulus cyclophosphamide

[Term]
id: ECTO:0900255
name: exposure to cyromazine via ingestion
def: "An exposure to cyromazine via ingestion route." []
synonym: "cyromazine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002316 ! exposure to cyromazine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:30260 ! has exposure stimulus cyromazine

[Term]
id: ECTO:0900256
name: exposure to cysteamine via ingestion
def: "An exposure to cysteamine via ingestion route." []
synonym: "cysteamine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002317 ! exposure to cysteamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17141 ! has exposure stimulus cysteamine

[Term]
id: ECTO:0900257
name: exposure to D-alanine via ingestion
def: "An exposure to D-alanine via ingestion route." []
synonym: "D-alanine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002290 ! exposure to D-alanine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15570 ! has exposure stimulus D-alanine

[Term]
id: ECTO:0900258
name: exposure to dabigatran etexilate via ingestion
def: "An exposure to dabigatran etexilate via ingestion route." []
synonym: "dabigatran etexilate exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002759 ! exposure to dabigatran etexilate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:70746 ! has exposure stimulus dabigatran etexilate

[Term]
id: ECTO:0900259
name: exposure to platycodin D via ingestion
def: "An exposure to platycodin D via ingestion route." []
synonym: "platycodin D exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002867 ! exposure to platycodin D
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:70436 ! has exposure stimulus platycodin D

[Term]
id: ECTO:0900260
name: exposure to eriodictyol via ingestion
def: "An exposure to eriodictyol via ingestion route." []
synonym: "eriodictyol exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002357 ! exposure to eriodictyol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28412 ! has exposure stimulus eriodictyol

[Term]
id: ECTO:0900261
name: exposure to methylglyoxal via ingestion
def: "An exposure to methylglyoxal via ingestion route." []
synonym: "methylglyoxal exposure via ingestion route" EXACT []
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000301 ! exposure to methylglyoxal
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17158 ! has exposure stimulus methylglyoxal

[Term]
id: ECTO:0900262
name: exposure to dehydroepiandrosterone via ingestion
def: "An exposure to dehydroepiandrosterone via ingestion route." []
synonym: "dehydroepiandrosterone exposure via ingestion route" EXACT []
is_a: ECTO:0900001 ! exposure to oral steroids
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000441 ! exposure to dehydroepiandrosterone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28689 ! has exposure stimulus dehydroepiandrosterone

[Term]
id: ECTO:0900263
name: exposure to sodium benzoate via ingestion
def: "An exposure to sodium benzoate via ingestion route." []
synonym: "sodium benzoate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002693 ! exposure to sodium benzoate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:113455 ! has exposure stimulus sodium benzoate

[Term]
id: ECTO:0900264
name: exposure to deuterium atom via ingestion
def: "An exposure to deuterium atom via ingestion route." []
synonym: "deuterium atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002331 ! exposure to deuterium atom
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:29237 ! has exposure stimulus deuterium atom

[Term]
id: ECTO:0900265
name: exposure to dexmedetomidine via injection
def: "An exposure to dexmedetomidine via injection route." []
synonym: "dexmedetomidine exposure via injection route" EXACT []
is_a: ECTO:9002332 ! exposure to dexmedetomidine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:4466 ! has exposure stimulus dexmedetomidine
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900266
name: exposure to diallyl disulfide via ingestion
def: "An exposure to diallyl disulfide via ingestion route." []
synonym: "diallyl disulfide exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002335 ! exposure to diallyl disulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:4488 ! has exposure stimulus diallyl disulfide

[Term]
id: ECTO:0900267
name: exposure to dieldrin via ingestion
def: "An exposure to dieldrin via ingestion route." []
synonym: "dieldrin exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001430 ! exposure to dieldrin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:34696 ! has exposure stimulus dieldrin

[Term]
id: ECTO:0900268
name: exposure to nutraceutical via ingestion
def: "An exposure to nutraceutical via ingestion route." []
synonym: "nutraceutical exposure via ingestion route" EXACT []
is_a: ECTO:9001865 ! exposure to nutraceutical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50733 ! has exposure stimulus nutraceutical
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900269
name: exposure to triglyceride in food via ingestion
def: "An exposure to triglyceride via ingestion route." []
synonym: "triglyceride exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000236 ! exposure to triglyceride
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17855 ! has exposure stimulus triglyceride

[Term]
id: ECTO:0900270
name: exposure to hexadecanoic acid via ingestion
def: "An exposure to hexadecanoic acid via ingestion route." []
synonym: "hexadecanoic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002185 ! exposure to hexadecanoic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15756 ! has exposure stimulus hexadecanoic acid

[Term]
id: ECTO:0900271
name: exposure to L-asparagine via ingestion
def: "An exposure to L-asparagine via ingestion route." []
synonym: "L-asparagine exposure via ingestion route" EXACT []
is_a: ECTO:0900209 ! exposure to asparagine via ingestion
is_a: ECTO:9002764 ! exposure to L-asparagine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17196 ! has exposure stimulus L-asparagine

[Term]
id: ECTO:0900272
name: exposure to bis(2-ethylhexyl) phthalate via ingestion
def: "An exposure to bis(2-ethylhexyl) phthalate via ingestion route." []
synonym: "bis(2-ethylhexyl) phthalate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001525 ! exposure to bis(2-ethylhexyl) phthalate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17747 ! has exposure stimulus bis(2-ethylhexyl) phthalate

[Term]
id: ECTO:0900273
name: exposure to dimethyl fumarate via ingestion
def: "An exposure to dimethyl fumarate via ingestion route." []
synonym: "dimethyl fumarate exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002770 ! exposure to dimethyl fumarate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:76004 ! has exposure stimulus dimethyl fumarate

[Term]
id: ECTO:0900274
name: exposure to dinocap via ingestion
def: "An exposure to dinocap via ingestion route." []
synonym: "dinocap exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001100 ! exposure to dinocap
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:83379 ! has exposure stimulus dinocap

[Term]
id: ECTO:0900275
name: exposure to EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor via ingestion
def: "An exposure to EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor via ingestion route." []
synonym: "EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor exposure via ingestion route" EXACT []
is_a: ECTO:9002035 ! exposure to EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:76893 ! has exposure stimulus EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900276
name: exposure to disulfiram via ingestion
def: "An exposure to disulfiram via ingestion route." []
synonym: "disulfiram exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001434 ! exposure to disulfiram
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:4659 ! has exposure stimulus disulfiram

[Term]
id: ECTO:0900277
name: exposure to dimethyl sulfoxide via ingestion
def: "An exposure to dimethyl sulfoxide via ingestion route." []
synonym: "dimethyl sulfoxide exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000492 ! exposure to dimethyl sulfoxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28262 ! has exposure stimulus dimethyl sulfoxide

[Term]
id: ECTO:0900278
name: exposure to double-stranded RNA via inhalation
def: "An exposure to double-stranded RNA via inhalation route." []
synonym: "double-stranded RNA exposure via inhalation route" EXACT []
is_a: ECTO:9000272 ! exposure to double-stranded RNA
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:67208 ! has exposure stimulus double-stranded RNA
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900279
name: exposure to dolutegravir via ingestion
def: "An exposure to dolutegravir via ingestion route." []
synonym: "dolutegravir exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002771 ! exposure to dolutegravir
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:76010 ! has exposure stimulus dolutegravir

[Term]
id: ECTO:0900280
name: exposure to doxorubicin via ingestion
def: "An exposure to doxorubicin via ingestion route." []
synonym: "doxorubicin exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000419 ! exposure to doxorubicin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28748 ! has exposure stimulus doxorubicin

[Term]
id: ECTO:0900281
name: exposure to duloxetine via ingestion
def: "An exposure to duloxetine via ingestion route." []
synonym: "duloxetine exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002346 ! exposure to duloxetine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:36796 ! has exposure stimulus duloxetine

[Term]
id: ECTO:0900282
name: exposure to EDTA(2-) via ingestion
def: "An exposure to EDTA(2-) via ingestion route." []
synonym: "EDTA(2-) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000110 ! exposure to EDTA(2-)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:64755 ! has exposure stimulus EDTA(2-)

[Term]
id: ECTO:0900283
name: exposure to ellagic acid via ingestion
def: "An exposure to ellagic acid via ingestion route." []
synonym: "ellagic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900092 ! exposure to polyphenol via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002775 ! exposure to ellagic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:4775 ! has exposure stimulus ellagic acid

[Term]
id: ECTO:0900284
name: exposure to emodin via ingestion
def: "An exposure to emodin via ingestion route." []
synonym: "emodin exposure via ingestion route" EXACT []
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002776 ! exposure to emodin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:42223 ! has exposure stimulus emodin

[Term]
id: ECTO:0900285
name: exposure to myricetin via ingestion
def: "An exposure to myricetin via ingestion route." []
synonym: "myricetin exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:9002506 ! exposure to myricetin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18152 ! has exposure stimulus myricetin

[Term]
id: ECTO:0900286
name: exposure to esketamine via inhalation
def: "An exposure to esketamine via inhalation route." []
synonym: "esketamine exposure via inhalation route" EXACT []
is_a: ECTO:9000750 ! exposure to esketamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:60799 ! has exposure stimulus esketamine
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900287
name: exposure to estradiol via injection
def: "An exposure to estradiol via injection route." []
synonym: "estradiol exposure via injection route" EXACT []
is_a: ECTO:9000212 ! exposure to estradiol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:23965 ! has exposure stimulus estradiol
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900288
name: exposure to etanercept via injection
def: "An exposure to etanercept via injection route." []
synonym: "etanercept exposure via injection route" EXACT []
is_a: ECTO:9002710 ! exposure to etanercept
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:4875 ! has exposure stimulus etanercept
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900289
name: exposure to etomidate via injection
def: "An exposure to etomidate via injection route." []
synonym: "etomidate exposure via injection route" EXACT []
is_a: ECTO:9002359 ! exposure to etomidate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:4910 ! has exposure stimulus etomidate
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900290
name: exposure to O-methyleugenol via inhalation
def: "An exposure to O-methyleugenol via inhalation route." []
synonym: "O-methyleugenol exposure via inhalation route" EXACT []
is_a: ECTO:9001162 ! exposure to O-methyleugenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:4918 ! has exposure stimulus O-methyleugenol
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900291
name: exposure to Schisantherin A via ingestion
def: "An exposure to Schisantherin A via ingestion route." []
synonym: "Schisantherin A exposure via ingestion route" EXACT []
is_a: ECTO:0900092 ! exposure to polyphenol via ingestion
is_a: ECTO:9002878 ! exposure to Schisantherin A
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:9048 ! has exposure stimulus Schisantherin A

[Term]
id: ECTO:0900292
name: maternal exposure to antigen
def: "An exposure to antigen via maternal transfer." []
synonym: "antigen exposure via maternal" EXACT []
is_a: ECTO:9001898 ! exposure to antigen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:59132 ! has exposure stimulus antigen
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900293
name: exposure to chitosan via ingestion
def: "An exposure to chitosan via ingestion route." []
synonym: "chitosan exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002745 ! exposure to chitosan
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16261 ! has exposure stimulus chitosan

[Term]
id: ECTO:0900294
name: exposure to fluoride via ingestion
def: "An exposure to fluoride via ingestion route." []
synonym: "fluoride exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000423 ! exposure to fluoride
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17051 ! has exposure stimulus fluoride

[Term]
id: ECTO:0900295
name: exposure to fluoxetine via injection
def: "An exposure to fluoxetine via injection route." []
synonym: "fluoxetine exposure via injection route" EXACT []
is_a: ECTO:9000204 ! exposure to fluoxetine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:5118 ! has exposure stimulus fluoxetine
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900296
name: exposure to formaldehyde via ingestion
def: "An exposure to formaldehyde via ingestion route." []
synonym: "formaldehyde exposure via ingestion route" EXACT []
is_a: ECTO:0000439 ! exposure to formaldehyde
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16842 ! has exposure stimulus formaldehyde

[Term]
id: ECTO:0900297
name: exposure to antifungal agent via ingestion
def: "An exposure to antifungal agent via ingestion route." []
synonym: "antifungal agent exposure via ingestion route" EXACT []
is_a: ECTO:9001749 ! exposure to antifungal agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35718 ! has exposure stimulus antifungal agent
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900298
name: exposure to gabapentin via ingestion
def: "An exposure to gabapentin via ingestion route." []
synonym: "gabapentin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000704 ! exposure to gabapentin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:42797 ! has exposure stimulus gabapentin

[Term]
id: ECTO:0900299
name: exposure to galactose via ingestion
def: "An exposure to galactose via ingestion route." []
synonym: "galactose exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9002385 ! exposure to galactose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28260 ! has exposure stimulus galactose

[Term]
id: ECTO:0900300
name: exposure to oxolane via inhalation
def: "An exposure to oxolane via inhalation route." []
synonym: "oxolane exposure via inhalation route" EXACT []
is_a: ECTO:9001506 ! exposure to oxolane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:26911 ! has exposure stimulus oxolane
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900301
name: exposure to gefitinib via ingestion
def: "An exposure to gefitinib via ingestion route." []
synonym: "gefitinib exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002388 ! exposure to gefitinib
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:49668 ! has exposure stimulus gefitinib

[Term]
id: ECTO:0900302
name: exposure to gemcitabine via ingestion
def: "An exposure to gemcitabine via ingestion route." []
synonym: "gemcitabine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000258 ! exposure to gemcitabine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:175901 ! has exposure stimulus gemcitabine

[Term]
id: ECTO:0900303
name: exposure to glucocorticoid via inhalation
def: "An exposure to glucocorticoid via inhalation route." []
synonym: "glucocorticoid exposure via inhalation route" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:0900250 ! exposure to corticosteroid via inhalation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:24261 ! has exposure stimulus glucocorticoid

[Term]
id: ECTO:0900304
name: exposure to EC 3.1.3.11 (fructose-bisphosphatase) inhibitor via ingestion
def: "An exposure to EC 3.1.3.11 (fructose-bisphosphatase) inhibitor via ingestion route." []
synonym: "EC 3.1.3.11 (fructose-bisphosphatase) inhibitor exposure via ingestion route" EXACT []
is_a: ECTO:9001968 ! exposure to EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:65056 ! has exposure stimulus EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900305
name: exposure to glucosinolate via ingestion
def: "An exposure to glucosinolate via ingestion route." []
synonym: "glucosinolate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002337 ! exposure to glucosinolate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:24279 ! has exposure stimulus glucosinolate

[Term]
id: ECTO:0900306
name: exposure to glutamate(2-) via ingestion
def: "An exposure to glutamate(2-) via ingestion route." []
synonym: "glutamate(2-) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002399 ! exposure to glutamate(2-)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:29987 ! has exposure stimulus glutamate(2-)

[Term]
id: ECTO:0900307
name: exposure to glutamine via ingestion
def: "An exposure to glutamine via ingestion route." []
synonym: "glutamine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002797 ! exposure to glutamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28300 ! has exposure stimulus glutamine

[Term]
id: ECTO:0900308
name: exposure to N-acetyl-L-cysteine via ingestion
def: "An exposure to N-acetyl-L-cysteine via ingestion route." []
synonym: "N-acetyl-L-cysteine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002508 ! exposure to N-acetyl-L-cysteine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28939 ! has exposure stimulus N-acetyl-L-cysteine

[Term]
id: ECTO:0900309
name: exposure to Gly-Pro via ingestion
def: "An exposure to Gly-Pro via ingestion route." []
synonym: "Gly-Pro exposure via ingestion route" EXACT []
is_a: ECTO:0900059 ! exposure to peptide via ingestion
is_a: ECTO:9002402 ! exposure to Gly-Pro
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:70744 ! has exposure stimulus Gly-Pro

[Term]
id: ECTO:0900310
name: exposure to L-glyceraldehyde via ingestion
def: "An exposure to L-glyceraldehyde via ingestion route." []
synonym: "L-glyceraldehyde exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9002447 ! exposure to L-glyceraldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27975 ! has exposure stimulus L-glyceraldehyde

[Term]
id: ECTO:0900311
name: exposure to glyphosate via ingestion
def: "An exposure to glyphosate via ingestion route." []
synonym: "glyphosate exposure via ingestion route" EXACT []
is_a: ECTO:0900088 ! exposure to phosphorus via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002138 ! exposure to glyphosate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27744 ! has exposure stimulus glyphosate

[Term]
id: ECTO:0900312
name: exposure to triptorelin via injection
def: "An exposure to triptorelin via injection route." []
synonym: "triptorelin exposure via injection route" EXACT []
is_a: ECTO:0900469 ! exposure to peptide via injection
is_a: ECTO:9002406 ! exposure to triptorelin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:63633 ! has exposure stimulus triptorelin

[Term]
id: ECTO:0900313
name: exposure to catechin via ingestion
def: "An exposure to catechin via ingestion route." []
synonym: "catechin exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:9000412 ! exposure to catechin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:23053 ! has exposure stimulus catechin

[Term]
id: ECTO:0900314
name: exposure to guanidinoacetic acid via ingestion
def: "An exposure to guanidinoacetic acid via ingestion route." []
synonym: "guanidinoacetic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002408 ! exposure to guanidinoacetic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16344 ! has exposure stimulus guanidinoacetic acid

[Term]
id: ECTO:0900315
name: exposure to GW 501516 via injection
def: "An exposure to GW 501516 via injection route." []
synonym: "GW 501516 exposure via injection route" EXACT []
is_a: ECTO:9002411 ! exposure to GW 501516
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:73726 ! has exposure stimulus GW 501516
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900316
name: exposure to haloperidol via ingestion
def: "An exposure to haloperidol via ingestion route." []
synonym: "haloperidol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000512 ! exposure to haloperidol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:5613 ! has exposure stimulus haloperidol

[Term]
id: ECTO:0900317
name: exposure to hepatotoxic agent via ingestion
def: "An exposure to hepatotoxic agent via ingestion route." []
synonym: "hepatotoxic agent exposure via ingestion route" EXACT []
is_a: ECTO:9001877 ! exposure to hepatotoxic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50908 ! has exposure stimulus hepatotoxic agent
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900318
name: exposure to haloacetic acid via ingestion
def: "An exposure to haloacetic acid via ingestion route." []
synonym: "haloacetic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002412 ! exposure to haloacetic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16277 ! has exposure stimulus haloacetic acid

[Term]
id: ECTO:0900319
name: exposure to hesperidin via ingestion
def: "An exposure to hesperidin via ingestion route." []
synonym: "hesperidin exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002800 ! exposure to hesperidin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28775 ! has exposure stimulus hesperidin

[Term]
id: ECTO:0900320
name: exposure to oligosaccharide via ingestion
def: "An exposure to oligosaccharide via ingestion route." []
synonym: "oligosaccharide exposure via ingestion route" EXACT []
is_a: ECTO:0900050 ! exposure to carbohydrate via ingestion
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50699 ! has exposure stimulus oligosaccharide

[Term]
id: ECTO:0900321
name: exposure to 4-hydroxynonenal via injection
def: "An exposure to 4-hydroxynonenal via injection route." []
synonym: "4-hydroxynonenal exposure via injection route" EXACT []
is_a: ECTO:9002203 ! exposure to 4-hydroxynonenal
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:142593 ! has exposure stimulus 4-hydroxynonenal
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900322
name: exposure to hydrochlorothiazide via ingestion
def: "An exposure to hydrochlorothiazide via ingestion route." []
synonym: "hydrochlorothiazide exposure via ingestion route" EXACT []
is_a: ECTO:0900096 ! exposure to thiazide via ingestion
is_a: ECTO:9000741 ! exposure to hydrochlorothiazide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:5778 ! has exposure stimulus hydrochlorothiazide

[Term]
id: ECTO:0900323
name: exposure to corticosteroid via ingestion
def: "An exposure to corticosteroid via ingestion route." []
synonym: "corticosteroid exposure via ingestion route" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
is_a: ECTO:0900001 ! exposure to oral steroids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50858 ! has exposure stimulus corticosteroid

[Term]
id: ECTO:0900324
name: exposure to dihydrogen via inhalation
def: "An exposure to dihydrogen via inhalation route." []
synonym: "dihydrogen exposure via inhalation route" EXACT []
is_a: ECTO:9002806 ! exposure to dihydrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:18276 ! has exposure stimulus dihydrogen
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900325
name: maternal exposure to hydrogen peroxide
def: "An exposure to hydrogen peroxide via maternal transfer." []
synonym: "hydrogen peroxide exposure via maternal" EXACT []
is_a: ECTO:9000267 ! exposure to hydrogen peroxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:16240 ! has exposure stimulus hydrogen peroxide
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900326
name: exposure to hydroxychloroquine via ingestion
def: "An exposure to hydroxychloroquine via ingestion route." []
synonym: "hydroxychloroquine exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002419 ! exposure to hydroxychloroquine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:5801 ! has exposure stimulus hydroxychloroquine

[Term]
id: ECTO:0900327
name: exposure to hydroxytyrosol via ingestion
def: "An exposure to hydroxytyrosol via ingestion route." []
synonym: "hydroxytyrosol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:9002761 ! exposure to hydroxytyrosol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:68889 ! has exposure stimulus hydroxytyrosol

[Term]
id: ECTO:0900328
name: exposure to indapamide via ingestion
def: "An exposure to indapamide via ingestion route." []
synonym: "indapamide exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002892 ! exposure to indapamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:5893 ! has exposure stimulus indapamide

[Term]
id: ECTO:0900329
name: exposure to indole-3-butyric acid via ingestion
def: "An exposure to indole-3-butyric acid via ingestion route." []
synonym: "indole-3-butyric acid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000340 ! exposure to indole-3-butyric acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33070 ! has exposure stimulus indole-3-butyric acid

[Term]
id: ECTO:0900330
name: exposure to indole-3-carboxylate via ingestion
def: "An exposure to indole-3-carboxylate via ingestion route." []
synonym: "indole-3-carboxylate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002855 ! exposure to indole-3-carboxylate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:62448 ! has exposure stimulus indole-3-carboxylate

[Term]
id: ECTO:0900331
name: exposure to indoxyl sulfate(1-) via ingestion
def: "An exposure to indoxyl sulfate(1-) via ingestion route." []
synonym: "indoxyl sulfate(1-) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002427 ! exposure to indoxyl sulfate(1-)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:144643 ! has exposure stimulus indoxyl sulfate(1-)

[Term]
id: ECTO:0900332
name: exposure to nitrate via ingestion
def: "An exposure to nitrate via ingestion route." []
synonym: "nitrate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000185 ! exposure to nitrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17632 ! has exposure stimulus nitrate

[Term]
id: ECTO:0900333
name: exposure to Sir2 inhibitor via ingestion
def: "An exposure to Sir2 inhibitor via ingestion route." []
synonym: "Sir2 inhibitor exposure via ingestion route" EXACT []
is_a: ECTO:9002004 ! exposure to Sir2 inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:71181 ! has exposure stimulus Sir2 inhibitor
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900334
name: exposure to ionophore via ingestion
def: "An exposure to ionophore via ingestion route." []
synonym: "ionophore exposure via ingestion route" EXACT []
is_a: ECTO:9001669 ! exposure to ionophore
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:24869 ! has exposure stimulus ionophore
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900335
name: exposure to isobutyraldehyde via inhalation
def: "An exposure to isobutyraldehyde via inhalation route." []
synonym: "isobutyraldehyde exposure via inhalation route" EXACT []
is_a: ECTO:9001142 ! exposure to isobutyraldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:48943 ! has exposure stimulus isobutyraldehyde
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900336
name: exposure to isoprenaline via injection
def: "An exposure to isoprenaline via injection route." []
synonym: "isoprenaline exposure via injection route" EXACT []
is_a: ECTO:9001375 ! exposure to isoprenaline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:64317 ! has exposure stimulus isoprenaline
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900337
name: exposure to itaconate(2-) via inhalation
def: "An exposure to itaconate(2-) via inhalation route." []
synonym: "itaconate(2-) exposure via inhalation route" EXACT []
is_a: ECTO:9002434 ! exposure to itaconate(2-)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:17240 ! has exposure stimulus itaconate(2-)
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900338
name: exposure to YK-4-279 via injection
def: "An exposure to YK-4-279 via injection route." []
synonym: "YK-4-279 exposure via injection route" EXACT []
is_a: ECTO:9002907 ! exposure to YK-4-279
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:94301 ! has exposure stimulus YK-4-279
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900339
name: exposure to ketone via ingestion
def: "An exposure to ketone via ingestion route." []
synonym: "ketone exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17087 ! has exposure stimulus ketone

[Term]
id: ECTO:0900340
name: exposure to L-arginine via injection
def: "An exposure to L-arginine via injection route." []
synonym: "L-arginine exposure via injection route" EXACT []
is_a: ECTO:9000444 ! exposure to L-arginine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:16467 ! has exposure stimulus L-arginine
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900341
name: exposure to carnitine via ingestion
def: "An exposure to carnitine via ingestion route." []
synonym: "carnitine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002444 ! exposure to carnitine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17126 ! has exposure stimulus carnitine

[Term]
id: ECTO:0900342
name: exposure to L-citrulline via injection
def: "An exposure to L-citrulline via injection route." []
synonym: "L-citrulline exposure via injection route" EXACT []
is_a: ECTO:9002445 ! exposure to L-citrulline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:16349 ! has exposure stimulus L-citrulline
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900343
name: exposure to L-leucine via ingestion
def: "An exposure to L-leucine via ingestion route." []
synonym: "L-leucine exposure via ingestion route" EXACT []
is_a: ECTO:0900353 ! exposure to leucine via ingestion
is_a: ECTO:9002765 ! exposure to L-leucine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15603 ! has exposure stimulus L-leucine

[Term]
id: ECTO:0900344
name: exposure to L-arginine via ingestion
def: "An exposure to L-arginine via ingestion route." []
synonym: "L-arginine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000444 ! exposure to L-arginine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16467 ! has exposure stimulus L-arginine

[Term]
id: ECTO:0900345
name: exposure to lamotrigine via ingestion
def: "An exposure to lamotrigine via ingestion route." []
synonym: "lamotrigine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000755 ! exposure to lamotrigine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:6367 ! has exposure stimulus lamotrigine

[Term]
id: ECTO:0900346
name: exposure to carnitine via injection
def: "An exposure to carnitine via injection route." []
synonym: "carnitine exposure via injection route" EXACT []
is_a: ECTO:9002444 ! exposure to carnitine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:17126 ! has exposure stimulus carnitine
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900347
name: exposure to lead(2+) via ingestion
def: "An exposure to lead(2+) via ingestion route." []
synonym: "lead(2+) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002452 ! exposure to lead(2+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:49807 ! has exposure stimulus lead(2+)

[Term]
id: ECTO:0900348
name: maternal exposure to lead(2+)
def: "An exposure to lead(2+) via maternal transfer." []
synonym: "lead(2+) exposure via maternal" EXACT []
is_a: ECTO:0900351 ! maternal exposure to lead
is_a: ECTO:9002452 ! exposure to lead(2+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:49807 ! has exposure stimulus lead(2+)

[Term]
id: ECTO:0900349
name: exposure to lead nitrate via injection
def: "An exposure to lead nitrate via injection route." []
synonym: "lead nitrate exposure via injection route" EXACT []
is_a: ECTO:9002453 ! exposure to lead nitrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:37187 ! has exposure stimulus lead nitrate
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900350
name: exposure to lead nitrate via ingestion
def: "An exposure to lead nitrate via ingestion route." []
synonym: "lead nitrate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002453 ! exposure to lead nitrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:37187 ! has exposure stimulus lead nitrate

[Term]
id: ECTO:0900351
name: maternal exposure to lead
def: "An exposure to lead via maternal transfer." []
synonym: "lead molecular entity exposure via maternal" EXACT []
is_a: ECTO:9000945 ! exposure to lead
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:33585 ! has exposure stimulus lead molecular entity
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900352
name: exposure to letrozole via ingestion
def: "An exposure to letrozole via ingestion route." []
synonym: "letrozole exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002457 ! exposure to letrozole
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:6413 ! has exposure stimulus letrozole

[Term]
id: ECTO:0900353
name: exposure to leucine via ingestion
def: "An exposure to leucine via ingestion route." []
synonym: "leucine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000269 ! exposure to leucine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25017 ! has exposure stimulus leucine

[Term]
id: ECTO:0900354
name: exposure to L-dopa via ingestion
def: "An exposure to L-dopa via ingestion route." []
synonym: "L-dopa exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000475 ! exposure to L-dopa
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15765 ! has exposure stimulus L-dopa

[Term]
id: ECTO:0900355
name: exposure to lignocellulose via ingestion
def: "An exposure to lignocellulose via ingestion route." []
synonym: "lignocellulose exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002461 ! exposure to lignocellulose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:180683 ! has exposure stimulus lignocellulose

[Term]
id: ECTO:0900356
name: exposure to EC 3.1.1.3 (triacylglycerol lipase) inhibitor via ingestion
def: "An exposure to EC 3.1.1.3 (triacylglycerol lipase) inhibitor via ingestion route." []
synonym: "EC 3.1.1.3 (triacylglycerol lipase) inhibitor exposure via ingestion route" EXACT []
is_a: ECTO:9001966 ! exposure to EC 3.1.1.3 (triacylglycerol lipase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:65001 ! has exposure stimulus EC 3.1.1.3 (triacylglycerol lipase) inhibitor
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900357
name: exposure to lipopolysaccharide via injection
def: "An exposure to lipopolysaccharide via injection route." []
synonym: "lipopolysaccharide exposure via injection route" EXACT []
is_a: ECTO:9000215 ! exposure to lipopolysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:16412 ! has exposure stimulus lipopolysaccharide
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900358
name: exposure to lithium(1+) via ingestion
def: "An exposure to lithium(1+) via ingestion route." []
synonym: "lithium(1+) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000188 ! exposure to lithium(1+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:49713 ! has exposure stimulus lithium(1+)

[Term]
id: ECTO:0900359
name: exposure to heparin via ingestion
def: "An exposure to heparin via ingestion route." []
synonym: "heparin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000011 ! exposure to heparin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28304 ! has exposure stimulus heparin

[Term]
id: ECTO:0900360
name: exposure to loxoprofen via ingestion
def: "An exposure to loxoprofen via ingestion route." []
synonym: "loxoprofen exposure via ingestion route" EXACT []
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002467 ! exposure to loxoprofen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:76172 ! has exposure stimulus loxoprofen

[Term]
id: ECTO:0900361
name: exposure to lipopolysaccharide via ingestion
def: "An exposure to lipopolysaccharide via ingestion route." []
synonym: "lipopolysaccharide exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000215 ! exposure to lipopolysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16412 ! has exposure stimulus lipopolysaccharide

[Term]
id: ECTO:0900362
name: exposure to lysophosphatidic acid via ingestion
def: "An exposure to lysophosphatidic acid via ingestion route." []
synonym: "lysophosphatidic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900088 ! exposure to phosphorus via ingestion
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002689 ! exposure to lysophosphatidic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:132742 ! has exposure stimulus lysophosphatidic acid

[Term]
id: ECTO:0900363
name: exposure to fuel additive via ingestion
def: "An exposure to fuel additive via ingestion route." []
synonym: "fuel additive exposure via ingestion route" EXACT []
is_a: ECTO:9001926 ! exposure to fuel additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:62803 ! has exposure stimulus fuel additive
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900364
name: maternal exposure to manganese cation
def: "An exposure to manganese cation via maternal transfer." []
synonym: "manganese cation exposure via maternal" EXACT []
is_a: ECTO:9000179 ! exposure to manganese cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:25155 ! has exposure stimulus manganese cation
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900365
name: exposure to manganese cation via ingestion
def: "An exposure to manganese cation via ingestion route." []
synonym: "manganese cation exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000179 ! exposure to manganese cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25155 ! has exposure stimulus manganese cation

[Term]
id: ECTO:0900366
name: exposure to mannan via ingestion
def: "An exposure to mannan via ingestion route." []
synonym: "mannan exposure via ingestion route" EXACT []
is_a: ECTO:0900055 ! exposure to polysaccharide via ingestion
is_a: ECTO:9002474 ! exposure to mannan
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28808 ! has exposure stimulus mannan

[Term]
id: ECTO:0900367
name: exposure to mannitol via injection
def: "An exposure to mannitol via injection route." []
synonym: "mannitol exposure via injection route" EXACT []
is_a: ECTO:9000197 ! exposure to mannitol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:29864 ! has exposure stimulus mannitol
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900368
name: exposure to maslinic acid via ingestion
def: "An exposure to maslinic acid via ingestion route." []
synonym: "maslinic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002476 ! exposure to maslinic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:66682 ! has exposure stimulus maslinic acid

[Term]
id: ECTO:0900369
name: exposure to micronutrient via ingestion
def: "An exposure to micronutrient via ingestion route." []
synonym: "micronutrient exposure via ingestion route" EXACT []
is_a: ECTO:0900056 ! exposure to nutrient via ingestion
is_a: ECTO:9001687 ! exposure to micronutrient
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27027 ! has exposure stimulus micronutrient

[Term]
id: ECTO:0900370
name: maternal exposure to poly(I:C)
def: "An exposure to poly(I:C) via maternal transfer." []
synonym: "poly(I:C) exposure via maternal" EXACT []
is_a: ECTO:9002477 ! exposure to poly(I:C)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:84491 ! has exposure stimulus poly(I:C)
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900371
name: exposure to mitomycin C via injection
def: "An exposure to mitomycin C via injection route." []
synonym: "mitomycin C exposure via injection route" EXACT []
is_a: ECTO:9002493 ! exposure to mitomycin C
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:27504 ! has exposure stimulus mitomycin C
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900372
name: exposure to melphalan via injection
def: "An exposure to melphalan via injection route." []
synonym: "melphalan exposure via injection route" EXACT []
is_a: ECTO:9002482 ! exposure to melphalan
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:28876 ! has exposure stimulus melphalan
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900373
name: exposure to methanethiol via inhalation
def: "An exposure to methanethiol via inhalation route." []
synonym: "methanethiol exposure via inhalation route" EXACT []
is_a: ECTO:9001471 ! exposure to methanethiol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:16007 ! has exposure stimulus methanethiol
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900374
name: exposure to mercaptopurine via ingestion
def: "An exposure to mercaptopurine via ingestion route." []
synonym: "mercaptopurine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002210 ! exposure to mercaptopurine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50667 ! has exposure stimulus mercaptopurine

[Term]
id: ECTO:0900375
name: exposure to nanoparticle via ingestion
def: "An exposure to nanoparticle via ingestion route." []
synonym: "nanoparticle exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002233 ! exposure to nanoparticle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50803 ! has exposure stimulus nanoparticle

[Term]
id: ECTO:0900376
name: maternal exposure to heavy metal
def: "An exposure to heavy metal via maternal transfer." []
synonym: "heavy metal exposure via maternal" EXACT []
is_a: ECTO:9002163 ! exposure to heavy metal
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:5631 ! has exposure stimulus heavy metal
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900377
name: exposure to methadone via ingestion
def: "An exposure to methadone via ingestion route." []
synonym: "methadone exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000768 ! exposure to methadone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:6807 ! has exposure stimulus methadone

[Term]
id: ECTO:0900378
name: exposure to methotrexate via ingestion
def: "An exposure to methotrexate via ingestion route." []
synonym: "methotrexate exposure via ingestion route" EXACT []
is_a: ECTO:0000172 ! exposure to methotrexate
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:44185 ! has exposure stimulus methotrexate

[Term]
id: ECTO:0900379
name: exposure to metoprolol via ingestion
def: "An exposure to metoprolol via ingestion route." []
synonym: "metoprolol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000773 ! exposure to metoprolol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:6904 ! has exposure stimulus metoprolol

[Term]
id: ECTO:0900380
name: exposure to magnesium cation via ingestion
def: "An exposure to magnesium cation via ingestion route." []
synonym: "magnesium cation exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000210 ! exposure to magnesium cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:39127 ! has exposure stimulus magnesium cation

[Term]
id: ECTO:0900381
name: exposure to boscalid via ingestion
def: "An exposure to boscalid via ingestion route." []
synonym: "boscalid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000818 ! exposure to boscalid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:81822 ! has exposure stimulus boscalid

[Term]
id: ECTO:0900382
name: exposure to MnTBAP via injection
def: "An exposure to MnTBAP via injection route." []
synonym: "MnTBAP exposure via injection route" EXACT []
is_a: ECTO:9002833 ! exposure to MnTBAP
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:233143 ! has exposure stimulus MnTBAP
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900383
name: exposure to monensin A via ingestion
def: "An exposure to monensin A via ingestion route." []
synonym: "monensin A exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002498 ! exposure to monensin A
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27617 ! has exposure stimulus monensin A

[Term]
id: ECTO:0900384
name: exposure to monosodium L-glutamate via ingestion
def: "An exposure to monosodium L-glutamate via ingestion route." []
synonym: "monosodium L-glutamate exposure via ingestion route" EXACT []
is_a: ECTO:0900008 ! exposure to monosodium glutamate via ingestion
is_a: ECTO:9000488 ! exposure to monosodium L-glutamate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:64243 ! has exposure stimulus monosodium L-glutamate

[Term]
id: ECTO:0900385
name: exposure to monosodium urate via injection
def: "An exposure to monosodium urate via injection route." []
synonym: "monosodium urate exposure via injection route" EXACT []
is_a: ECTO:9002500 ! exposure to monosodium urate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:143125 ! has exposure stimulus monosodium urate
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900386
name: exposure to antimycobacterial drug via inhalation
def: "An exposure to antimycobacterial drug via inhalation route." []
synonym: "antimycobacterial drug exposure via inhalation route" EXACT []
is_a: ECTO:9001960 ! exposure to antimycobacterial drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:64912 ! has exposure stimulus antimycobacterial drug
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900387
name: exposure to mycophenolate mofetil via ingestion
def: "An exposure to mycophenolate mofetil via ingestion route." []
synonym: "mycophenolate mofetil exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002838 ! exposure to mycophenolate mofetil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8764 ! has exposure stimulus mycophenolate mofetil

[Term]
id: ECTO:0900388
name: exposure to N-methylserotonin via ingestion
def: "An exposure to N-methylserotonin via ingestion route." []
synonym: "N-methylserotonin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002856 ! exposure to N-methylserotonin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:48294 ! has exposure stimulus N-methylserotonin

[Term]
id: ECTO:0900389
name: exposure to nandrolone via injection
def: "An exposure to nandrolone via injection route." []
synonym: "nandrolone exposure via injection route" EXACT []
is_a: ECTO:9002840 ! exposure to nandrolone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:7466 ! has exposure stimulus nandrolone
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900390
name: exposure to naphthalene via inhalation
def: "An exposure to naphthalene via inhalation route." []
synonym: "naphthalene exposure via inhalation route" EXACT []
is_a: ECTO:9000552 ! exposure to naphthalene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:16482 ! has exposure stimulus naphthalene
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900391
name: exposure to neohesperidin dihydrochalcone via ingestion
def: "An exposure to neohesperidin dihydrochalcone via ingestion route." []
synonym: "neohesperidin dihydrochalcone exposure via ingestion route" EXACT []
is_a: ECTO:0900133 ! exposure to flavonoids via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000868 ! exposure to neohesperidin dihydrochalcone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:83535 ! has exposure stimulus neohesperidin dihydrochalcone

[Term]
id: ECTO:0900392
name: exposure to nevirapine via ingestion
def: "An exposure to nevirapine via ingestion route." []
synonym: "nevirapine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002511 ! exposure to nevirapine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:63613 ! has exposure stimulus nevirapine

[Term]
id: ECTO:0900393
name: exposure to nicotine via inhalation
def: "An exposure to nicotine via inhalation route." []
synonym: "nicotine exposure via inhalation route" EXACT []
is_a: ECTO:9000250 ! exposure to nicotine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:18723 ! has exposure stimulus nicotine
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900394
name: exposure to nitisinone via ingestion
def: "An exposure to nitisinone via ingestion route." []
synonym: "nitisinone exposure via ingestion route" EXACT []
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002517 ! exposure to nitisinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50378 ! has exposure stimulus nitisinone

[Term]
id: ECTO:0900395
name: exposure to dinitrogen via ingestion
def: "An exposure to dinitrogen via ingestion route." []
synonym: "dinitrogen exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002684 ! exposure to dinitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17997 ! has exposure stimulus dinitrogen

[Term]
id: ECTO:0900396
name: exposure to nitrite via ingestion
def: "An exposure to nitrite via ingestion route." []
synonym: "nitrite exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000341 ! exposure to nitrite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16301 ! has exposure stimulus nitrite

[Term]
id: ECTO:0900397
name: exposure to non-steroidal anti-inflammatory drug via injection
def: "An exposure to non-steroidal anti-inflammatory drug via injection route." []
synonym: "non-steroidal anti-inflammatory drug exposure via injection route" EXACT []
is_a: ECTO:9001720 ! exposure to non-steroidal anti-inflammatory drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:35475 ! has exposure stimulus non-steroidal anti-inflammatory drug
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900398
name: exposure to nortriptyline via ingestion
def: "An exposure to nortriptyline via ingestion route." []
synonym: "nortriptyline exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002713 ! exposure to nortriptyline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:7640 ! has exposure stimulus nortriptyline

[Term]
id: ECTO:0900399
name: exposure to nucleotide via ingestion
def: "An exposure to nucleotide via ingestion route." []
synonym: "nucleotide exposure via ingestion route" EXACT []
is_a: ECTO:0900088 ! exposure to phosphorus via ingestion
is_a: ECTO:9002338 ! exposure to nucleotide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:36976 ! has exposure stimulus nucleotide

[Term]
id: ECTO:0900400
name: exposure to nitisinone via injection
def: "An exposure to nitisinone via injection route." []
synonym: "nitisinone exposure via injection route" EXACT []
is_a: ECTO:9002517 ! exposure to nitisinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:50378 ! has exposure stimulus nitisinone
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900401
name: exposure to oleic acid via ingestion
def: "An exposure to oleic acid via ingestion route." []
synonym: "oleic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002527 ! exposure to oleic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16196 ! has exposure stimulus oleic acid

[Term]
id: ECTO:0900402
name: exposure to Ku-0063794 via ingestion
def: "An exposure to Ku-0063794 via ingestion route." []
synonym: "Ku-0063794 exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002503 ! exposure to Ku-0063794
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:85572 ! has exposure stimulus Ku-0063794

[Term]
id: ECTO:0900403
name: exposure to opioid analgesic via ingestion
def: "An exposure to opioid analgesic via ingestion route." []
synonym: "opioid analgesic exposure via ingestion route" EXACT []
is_a: ECTO:9001724 ! exposure to opioid analgesic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35482 ! has exposure stimulus opioid analgesic
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900404
name: maternal exposure to mu-opioid receptor agonist
def: "An exposure to mu-opioid receptor agonist via maternal transfer." []
synonym: "mu-opioid receptor agonist exposure via maternal" EXACT []
is_a: ECTO:0900043 ! exposure to drug via maternal
is_a: ECTO:9001896 ! exposure to mu-opioid receptor agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:55322 ! has exposure stimulus mu-opioid receptor agonist

[Term]
id: ECTO:0900405
name: exposure to oral contraceptive via ingestion
def: "An exposure to oral contraceptive via ingestion route." []
synonym: "oral contraceptive exposure via ingestion route" EXACT []
is_a: ECTO:9002149 ! exposure to oral contraceptive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:49325 ! has exposure stimulus oral contraceptive
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900406
name: exposure to lipid via ingestion
def: "An exposure to lipid via ingestion route." []
synonym: "lipid exposure via ingestion route" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18059 ! has exposure stimulus lipid

[Term]
id: ECTO:0900407
name: exposure to organonitrogen compound via ingestion
def: "An exposure to organonitrogen compound via ingestion route." []
synonym: "organonitrogen compound exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35352 ! has exposure stimulus organonitrogen compound

[Term]
id: ECTO:0900408
name: exposure to laxative via ingestion
def: "An exposure to laxative via ingestion route." []
synonym: "laxative exposure via ingestion route" EXACT []
is_a: ECTO:9001851 ! exposure to laxative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50503 ! has exposure stimulus laxative
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900409
name: exposure to Oxytetracycline hydrochloride via ingestion
def: "An exposure to Oxytetracycline hydrochloride via ingestion route." []
synonym: "Oxytetracycline hydrochloride exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002534 ! exposure to Oxytetracycline hydrochloride
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:31953 ! has exposure stimulus Oxytetracycline hydrochloride

[Term]
id: ECTO:0900410
name: exposure to paliperidone via ingestion
def: "An exposure to paliperidone via ingestion route." []
synonym: "paliperidone exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002538 ! exposure to paliperidone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:82978 ! has exposure stimulus paliperidone

[Term]
id: ECTO:0900411
name: exposure to palmitoleic acid via ingestion
def: "An exposure to palmitoleic acid via ingestion route." []
synonym: "palmitoleic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9000509 ! exposure to palmitoleic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28716 ! has exposure stimulus palmitoleic acid

[Term]
id: ECTO:0900412
name: exposure to Paeonol via ingestion
def: "An exposure to Paeonol via ingestion route." []
synonym: "Paeonol exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002537 ! exposure to Paeonol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:69581 ! has exposure stimulus Paeonol

[Term]
id: ECTO:0900413
name: exposure to pantothenic acid via ingestion
def: "An exposure to pantothenic acid via ingestion route." []
synonym: "pantothenic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002152 ! exposure to pantothenic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:7916 ! has exposure stimulus pantothenic acid

[Term]
id: ECTO:0900414
name: exposure to paracetamol via injection
def: "An exposure to paracetamol via injection route." []
synonym: "paracetamol exposure via injection route" EXACT []
is_a: ECTO:9000387 ! exposure to paracetamol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:46195 ! has exposure stimulus paracetamol
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900415
name: maternal exposure to paracetamol
def: "An exposure to paracetamol via maternal transfer." []
synonym: "paracetamol exposure via maternal" EXACT []
is_a: ECTO:9000387 ! exposure to paracetamol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:46195 ! has exposure stimulus paracetamol
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900416
name: exposure to paraquat via ingestion
def: "An exposure to paraquat via ingestion route." []
synonym: "paraquat exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000395 ! exposure to paraquat
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:34905 ! has exposure stimulus paraquat

[Term]
id: ECTO:0900417
name: exposure to 3-isobutyl-1-methylxanthine via ingestion
def: "An exposure to 3-isobutyl-1-methylxanthine via ingestion route." []
synonym: "3-isobutyl-1-methylxanthine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002198 ! exposure to 3-isobutyl-1-methylxanthine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:48518 ! has exposure stimulus 3-isobutyl-1-methylxanthine

[Term]
id: ECTO:0900418
name: exposure to perphenazine via ingestion
def: "An exposure to perphenazine via ingestion route." []
synonym: "perphenazine exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000355 ! exposure to perphenazine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8028 ! has exposure stimulus perphenazine

[Term]
id: ECTO:0900419
name: exposure to pesticide via ingestion
def: "An exposure to pesticide via ingestion route." []
synonym: "pesticide exposure via ingestion route" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25944 ! has exposure stimulus pesticide
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900420
name: exposure to zinc cation via injection
def: "An exposure to zinc cation via injection route." []
synonym: "zinc cation exposure via injection route" EXACT []
is_a: ECTO:9000180 ! exposure to zinc cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:63056 ! has exposure stimulus zinc cation
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900421
name: exposure to L-tyrosine via ingestion
def: "An exposure to L-tyrosine via ingestion route." []
synonym: "L-tyrosine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002186 ! exposure to L-tyrosine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17895 ! has exposure stimulus L-tyrosine

[Term]
id: ECTO:0900422
name: exposure to phenylephrine via injection
def: "An exposure to phenylephrine via injection route." []
synonym: "phenylephrine exposure via injection route" EXACT []
is_a: ECTO:9001383 ! exposure to phenylephrine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:8093 ! has exposure stimulus phenylephrine
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900423
name: exposure to N-phenylthiourea via ingestion
def: "An exposure to N-phenylthiourea via ingestion route." []
synonym: "N-phenylthiourea exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000422 ! exposure to N-phenylthiourea
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:46261 ! has exposure stimulus N-phenylthiourea

[Term]
id: ECTO:0900424
name: exposure to phenytoin via ingestion
def: "An exposure to phenytoin via ingestion route." []
synonym: "phenytoin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9001224 ! exposure to phenytoin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8107 ! has exposure stimulus phenytoin

[Term]
id: ECTO:0900425
name: exposure to sterol via ingestion
def: "An exposure to sterol via ingestion route." []
synonym: "sterol exposure via ingestion route" EXACT []
is_a: ECTO:0900001 ! exposure to oral steroids
is_a: ECTO:9000264 ! exposure to sterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15889 ! has exposure stimulus sterol

[Term]
id: ECTO:0900426
name: exposure to EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor via ingestion
def: "An exposure to EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor via ingestion route." []
synonym: "EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor exposure via ingestion route" EXACT []
is_a: ECTO:9001880 ! exposure to EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50914 ! has exposure stimulus EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900427
name: exposure to pioglitazone via ingestion
def: "An exposure to pioglitazone via ingestion route." []
synonym: "pioglitazone exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002555 ! exposure to pioglitazone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8228 ! has exposure stimulus pioglitazone

[Term]
id: ECTO:0900428
name: exposure to agomelatine via ingestion
def: "An exposure to agomelatine via ingestion route." []
synonym: "agomelatine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002225 ! exposure to agomelatine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:134990 ! has exposure stimulus agomelatine

[Term]
id: ECTO:0900429
name: exposure to poly(I:C) via injection
def: "An exposure to poly(I:C) via injection route." []
synonym: "poly(I:C) exposure via injection route" EXACT []
is_a: ECTO:0900099 ! exposure to double-stranded RNA via injection
is_a: ECTO:9002477 ! exposure to poly(I:C)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:84491 ! has exposure stimulus poly(I:C)

[Term]
id: ECTO:0900430
name: exposure to polyamine macromolecule via ingestion
def: "An exposure to polyamine macromolecule via ingestion route." []
synonym: "polyamine macromolecule exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000485 ! exposure to polyamine macromolecule
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:51349 ! has exposure stimulus polyamine macromolecule

[Term]
id: ECTO:0900431
name: exposure to disinfectant via inhalation
def: "An exposure to disinfectant via inhalation route." []
synonym: "disinfectant exposure via inhalation route" EXACT []
is_a: ECTO:0000657 ! exposure to disinfectant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:48219 ! has exposure stimulus disinfectant
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900432
name: exposure to 1-dodecylguanidine via inhalation
def: "An exposure to 1-dodecylguanidine via inhalation route." []
synonym: "1-dodecylguanidine exposure via inhalation route" EXACT []
is_a: ECTO:9001105 ! exposure to 1-dodecylguanidine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:74880 ! has exposure stimulus 1-dodecylguanidine
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900433
name: exposure to prednisolone via injection
def: "An exposure to prednisolone via injection route." []
synonym: "prednisolone exposure via injection route" EXACT []
is_a: ECTO:9000875 ! exposure to prednisolone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:8378 ! has exposure stimulus prednisolone
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900434
name: exposure to prednisolone via ingestion
def: "An exposure to prednisolone via ingestion route." []
synonym: "prednisolone exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900323 ! exposure to corticosteroid via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9000875 ! exposure to prednisolone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8378 ! has exposure stimulus prednisolone

[Term]
id: ECTO:0900435
name: exposure to beta-amyloid via injection
def: "An exposure to amyloid-beta via injection route." []
synonym: "amyloid-beta exposure via injection route" EXACT []
is_a: ECTO:0900469 ! exposure to peptide via injection
is_a: ECTO:9000501 ! exposure to beta-amyloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:64645 ! has exposure stimulus amyloid-beta

[Term]
id: ECTO:0900436
name: exposure to L-proline via ingestion
def: "An exposure to L-proline via ingestion route." []
synonym: "L-proline exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002568 ! exposure to L-proline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17203 ! has exposure stimulus L-proline

[Term]
id: ECTO:0900437
name: exposure to propofol via injection
def: "An exposure to propofol via injection route." []
synonym: "propofol exposure via injection route" EXACT []
is_a: ECTO:9002571 ! exposure to propofol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:44915 ! has exposure stimulus propofol
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900438
name: exposure to ethylene glycol via inhalation
def: "An exposure to ethylene glycol via inhalation route." []
synonym: "ethylene glycol exposure via inhalation route" EXACT []
is_a: ECTO:9001111 ! exposure to ethylene glycol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:30742 ! has exposure stimulus ethylene glycol
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900439
name: exposure to protein via inhalation
def: "An exposure to protein via inhalation route." []
synonym: "protein exposure via inhalation route" EXACT []
is_a: ECTO:9002133 ! exposure to protein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:36080 ! has exposure stimulus protein
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900440
name: exposure to puerarin via ingestion
def: "An exposure to puerarin via ingestion route." []
synonym: "puerarin exposure via ingestion route" EXACT []
is_a: ECTO:0900133 ! exposure to flavonoids via ingestion
is_a: ECTO:0900339 ! exposure to ketone via ingestion
is_a: ECTO:9002306 ! exposure to puerarin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8633 ! has exposure stimulus puerarin

[Term]
id: ECTO:0900441
name: exposure to pyrrolizidine alkaloid via ingestion
def: "An exposure to pyrrolizidine alkaloid via ingestion route." []
synonym: "pyrrolizidine alkaloid exposure via ingestion route" EXACT []
is_a: ECTO:0900477 ! exposure to alkaloid via ingestion
is_a: ECTO:9002577 ! exposure to pyrrolizidine alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:64948 ! has exposure stimulus pyrrolizidine alkaloid

[Term]
id: ECTO:0900442
name: exposure to quercetin via ingestion
def: "An exposure to quercetin via ingestion route." []
synonym: "quercetin exposure via ingestion route" EXACT []
is_a: ECTO:0900085 ! exposure to flavonoid via ingestion
is_a: ECTO:9001336 ! exposure to quercetin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16243 ! has exposure stimulus quercetin

[Term]
id: ECTO:0900443
name: exposure to quetiapine via ingestion
def: "An exposure to quetiapine via ingestion route." []
synonym: "quetiapine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000356 ! exposure to quetiapine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8707 ! has exposure stimulus quetiapine

[Term]
id: ECTO:0900444
name: exposure to queuine via ingestion
def: "An exposure to queuine via ingestion route." []
synonym: "queuine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002873 ! exposure to queuine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17433 ! has exposure stimulus queuine

[Term]
id: ECTO:0900445
name: exposure to insulin (human) via injection
def: "An exposure to insulin (human) via injection route." []
synonym: "insulin (human) exposure via injection route" EXACT []
is_a: ECTO:0900469 ! exposure to peptide via injection
is_a: ECTO:9002428 ! exposure to insulin (human)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:5931 ! has exposure stimulus insulin (human)

[Term]
id: ECTO:0900446
name: exposure to fibrin modulating drug via injection
def: "An exposure to fibrin modulating drug via injection route." []
synonym: "fibrin modulating drug exposure via injection route" EXACT []
is_a: ECTO:9001820 ! exposure to fibrin modulating drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:48676 ! has exposure stimulus fibrin modulating drug
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900447
name: exposure to fentanyl via injection
def: "An exposure to fentanyl via injection route." []
synonym: "fentanyl exposure via injection route" EXACT []
is_a: ECTO:9001521 ! exposure to fentanyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:119915 ! has exposure stimulus fentanyl
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900448
name: exposure to resveratrol via ingestion
def: "An exposure to resveratrol via ingestion route." []
synonym: "resveratrol exposure via ingestion route" EXACT []
is_a: ECTO:0900092 ! exposure to polyphenol via ingestion
is_a: ECTO:9000497 ! exposure to resveratrol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:27881 ! has exposure stimulus resveratrol

[Term]
id: ECTO:0900449
name: exposure to rhamnose via ingestion
def: "An exposure to rhamnose via ingestion route." []
synonym: "rhamnose exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9000211 ! exposure to rhamnose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26546 ! has exposure stimulus rhamnose

[Term]
id: ECTO:0900450
name: exposure to risperidone via ingestion
def: "An exposure to risperidone via ingestion route." []
synonym: "risperidone exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000357 ! exposure to risperidone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:8871 ! has exposure stimulus risperidone

[Term]
id: ECTO:0900451
name: exposure to rocuronium via injection
def: "An exposure to rocuronium via injection route." []
synonym: "rocuronium exposure via injection route" EXACT []
is_a: ECTO:9002585 ! exposure to rocuronium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:8884 ! has exposure stimulus rocuronium
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900452
name: exposure to fragrance via inhalation
def: "An exposure to fragrance via inhalation route." []
synonym: "fragrance exposure via inhalation route" EXACT []
is_a: ECTO:9001808 ! exposure to fragrance
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:48318 ! has exposure stimulus fragrance
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900453
name: exposure to rosuvastatin via ingestion
def: "An exposure to rosuvastatin via ingestion route." []
synonym: "rosuvastatin exposure via ingestion route" EXACT []
is_a: ECTO:0900064 ! exposure to statin via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000673 ! exposure to rosuvastatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:38545 ! has exposure stimulus rosuvastatin

[Term]
id: ECTO:0900454
name: exposure to rotenone via injection
def: "An exposure to rotenone via injection route." []
synonym: "rotenone exposure via injection route" EXACT []
is_a: ECTO:9000502 ! exposure to rotenone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:28201 ! has exposure stimulus rotenone
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900455
name: exposure to herbicide via ingestion
def: "An exposure to herbicide via ingestion route." []
synonym: "herbicide exposure via ingestion route" EXACT []
is_a: ECTO:0000515 ! exposure to herbicide
is_a: ECTO:0900419 ! exposure to pesticide via ingestion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:24527 ! has exposure stimulus herbicide

[Term]
id: ECTO:0900456
name: exposure to fluroxypyr via ingestion
def: "An exposure to fluroxypyr via ingestion route." []
synonym: "fluroxypyr exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000835 ! exposure to fluroxypyr
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:82017 ! has exposure stimulus fluroxypyr

[Term]
id: ECTO:0900457
name: exposure to 9-(beta-D-glucosyl)-trans-zeatin via ingestion
def: "An exposure to 9-(beta-D-glucosyl)-trans-zeatin via ingestion route." []
synonym: "9-(beta-D-glucosyl)-trans-zeatin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002319 ! exposure to 9-(beta-D-glucosyl)-trans-zeatin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:133210 ! has exposure stimulus 9-(beta-D-glucosyl)-trans-zeatin

[Term]
id: ECTO:0900458
name: exposure to lycopene via ingestion
def: "An exposure to lycopene via ingestion route." []
synonym: "lycopene exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9001335 ! exposure to lycopene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15948 ! has exposure stimulus lycopene

[Term]
id: ECTO:0900459
name: exposure to CB-5083 via injection
def: "An exposure to CB-5083 via injection route." []
synonym: "CB-5083 exposure via injection route" EXACT []
is_a: ECTO:9002740 ! exposure to CB-5083
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:232521 ! has exposure stimulus CB-5083
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900460
name: exposure to cell dedifferentiation agent via ingestion
def: "An exposure to cell dedifferentiation agent via ingestion route." []
synonym: "cell dedifferentiation agent exposure via ingestion route" EXACT []
is_a: ECTO:9001995 ! exposure to cell dedifferentiation agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:70724 ! has exposure stimulus cell dedifferentiation agent
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900461
name: exposure to second generation antipsychotic via ingestion
def: "An exposure to second generation antipsychotic via ingestion route." []
synonym: "second generation antipsychotic exposure via ingestion route" EXACT []
is_a: ECTO:9001973 ! exposure to second generation antipsychotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:65191 ! has exposure stimulus second generation antipsychotic
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900463
name: exposure to sertraline via ingestion
def: "An exposure to sertraline via ingestion route." []
synonym: "sertraline exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002593 ! exposure to sertraline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:9123 ! has exposure stimulus sertraline

[Term]
id: ECTO:0900464
name: exposure to silver(1+) via injection
def: "An exposure to silver(1+) via injection route." []
synonym: "silver(1+) exposure via injection route" EXACT []
is_a: ECTO:0900465 ! exposure to silver cation via injection
is_a: ECTO:9002342 ! exposure to silver(1+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:49468 ! has exposure stimulus silver(1+)

[Term]
id: ECTO:0900465
name: exposure to silver cation via injection
def: "An exposure to silver cation via injection route." []
synonym: "silver cation exposure via injection route" EXACT []
is_a: ECTO:9000193 ! exposure to silver cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:60253 ! has exposure stimulus silver cation
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900466
name: exposure to silver nanoparticle via ingestion
def: "An exposure to silver nanoparticle via ingestion route." []
synonym: "silver nanoparticle exposure via ingestion route" EXACT []
is_a: ECTO:0900375 ! exposure to nanoparticle via ingestion
is_a: ECTO:9002598 ! exposure to silver nanoparticle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:50826 ! has exposure stimulus silver nanoparticle

[Term]
id: ECTO:0900467
name: exposure to silicon dioxide via inhalation
def: "An exposure to silicon dioxide via inhalation route." []
synonym: "silicon dioxide exposure via inhalation route" EXACT []
is_a: ECTO:9000073 ! exposure to silicon dioxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:30563 ! has exposure stimulus silicon dioxide
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900468
name: exposure to melatonin via ingestion
def: "An exposure to melatonin via ingestion route." []
synonym: "melatonin exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002481 ! exposure to melatonin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:16796 ! has exposure stimulus melatonin

[Term]
id: ECTO:0900469
name: exposure to peptide via injection
def: "An exposure to peptide via injection route." []
synonym: "peptide exposure via injection route" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:16670 ! has exposure stimulus peptide
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900470
name: exposure to sodium atom via ingestion
def: "An exposure to sodium atom via ingestion route." []
synonym: "sodium atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002883 ! exposure to sodium atom
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26708 ! has exposure stimulus sodium atom

[Term]
id: ECTO:0900471
name: exposure to sodium acetate via ingestion
def: "An exposure to sodium acetate via ingestion route." []
synonym: "sodium acetate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002601 ! exposure to sodium acetate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:32954 ! has exposure stimulus sodium acetate

[Term]
id: ECTO:0900472
name: exposure to sodium butyrate via ingestion
def: "An exposure to sodium butyrate via ingestion route." []
synonym: "sodium butyrate exposure via ingestion route" EXACT []
is_a: ECTO:0900406 ! exposure to lipid via ingestion
is_a: ECTO:9002602 ! exposure to sodium butyrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:64103 ! has exposure stimulus sodium butyrate

[Term]
id: ECTO:0900473
name: exposure to sodium chloride via ingestion
def: "An exposure to sodium chloride via ingestion route." []
synonym: "sodium chloride exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001347 ! exposure to sodium chloride
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:26710 ! has exposure stimulus sodium chloride

[Term]
id: ECTO:0900474
name: exposure to sodium fluoride via ingestion
def: "An exposure to sodium fluoride via ingestion route." []
synonym: "sodium fluoride exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001529 ! exposure to sodium fluoride
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28741 ! has exposure stimulus sodium fluoride

[Term]
id: ECTO:0900475
name: exposure to sodium propionate via ingestion
def: "An exposure to sodium propionate via ingestion route." []
synonym: "sodium propionate exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002605 ! exposure to sodium propionate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:132106 ! has exposure stimulus sodium propionate

[Term]
id: ECTO:0900476
name: exposure to potassium(1+) via ingestion
def: "An exposure to potassium(1+) via ingestion route." []
synonym: "potassium(1+) exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000253 ! exposure to potassium(1+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:29103 ! has exposure stimulus potassium(1+)

[Term]
id: ECTO:0900477
name: exposure to alkaloid via ingestion
def: "An exposure to alkaloid via ingestion route." []
synonym: "alkaloid exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22315 ! has exposure stimulus alkaloid

[Term]
id: ECTO:0900478
name: exposure to sotalol via ingestion
def: "An exposure to sotalol via ingestion route." []
synonym: "sotalol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000754 ! exposure to sotalol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:63622 ! has exposure stimulus sotalol

[Term]
id: ECTO:0900479
name: exposure to oxygen-18 atom via ingestion
def: "An exposure to oxygen-18 atom via ingestion route." []
synonym: "oxygen-18 atom exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002533 ! exposure to oxygen-18 atom
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:33815 ! has exposure stimulus oxygen-18 atom

[Term]
id: ECTO:0900480
name: exposure to streptozocin via injection
def: "An exposure to streptozocin via injection route." []
synonym: "streptozocin exposure via injection route" EXACT []
is_a: ECTO:9001384 ! exposure to streptozocin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:9288 ! has exposure stimulus streptozocin
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900481
name: exposure to succinic acid via ingestion
def: "An exposure to succinic acid via ingestion route." []
synonym: "succinic acid exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002618 ! exposure to succinic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:15741 ! has exposure stimulus succinic acid

[Term]
id: ECTO:0900482
name: exposure to sulfoxaflor via ingestion
def: "An exposure to sulfoxaflor via ingestion route." []
synonym: "sulfoxaflor exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002621 ! exposure to sulfoxaflor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:133305 ! has exposure stimulus sulfoxaflor

[Term]
id: ECTO:0900483
name: exposure to sulfur dioxide via inhalation
def: "An exposure to sulfur dioxide via inhalation route." []
synonym: "sulfur dioxide exposure via inhalation route" EXACT []
is_a: ECTO:9000196 ! exposure to sulfur dioxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:18422 ! has exposure stimulus sulfur dioxide
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900484
name: exposure to tafenoquine via ingestion
def: "An exposure to tafenoquine via ingestion route." []
synonym: "tafenoquine exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002888 ! exposure to tafenoquine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:135752 ! has exposure stimulus tafenoquine

[Term]
id: ECTO:0900485
name: exposure to tamoxifen via ingestion
def: "An exposure to tamoxifen via ingestion route." []
synonym: "tamoxifen exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002223 ! exposure to tamoxifen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:41774 ! has exposure stimulus tamoxifen

[Term]
id: ECTO:0900486
name: exposure to taxane via injection
def: "An exposure to taxane via injection route." []
synonym: "taxane exposure via injection route" EXACT []
is_a: ECTO:9002628 ! exposure to taxane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:36064 ! has exposure stimulus taxane
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900487
name: exposure to 2,3,7,8-tetrachlorodibenzodioxine via ingestion
def: "An exposure to 2,3,7,8-tetrachlorodibenzodioxine via ingestion route." []
synonym: "2,3,7,8-tetrachlorodibenzodioxine exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9000490 ! exposure to 2,3,7,8-tetrachlorodibenzodioxine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28119 ! has exposure stimulus 2,3,7,8-tetrachlorodibenzodioxine

[Term]
id: ECTO:0900488
name: exposure to testosterone via injection
def: "An exposure to testosterone via injection route." []
synonym: "testosterone exposure via injection route" EXACT []
is_a: ECTO:9000228 ! exposure to testosterone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:17347 ! has exposure stimulus testosterone
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900489
name: exposure to mitogen via injection
def: "An exposure to mitogen via injection route." []
synonym: "mitogen exposure via injection route" EXACT []
is_a: ECTO:9001888 ! exposure to mitogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:52290 ! has exposure stimulus mitogen
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900490
name: exposure to thiamine(1+) via ingestion
def: "An exposure to thiamine(1+) via ingestion route." []
synonym: "thiamine(1+) exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900136 ! exposure to thiamine via ingestion
is_a: ECTO:9000191 ! exposure to thiamine(1+)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18385 ! has exposure stimulus thiamine(1+)

[Term]
id: ECTO:0900491
name: exposure to thiouracil via ingestion
def: "An exposure to thiouracil via ingestion route." []
synonym: "thiouracil exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002639 ! exposure to thiouracil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:348530 ! has exposure stimulus thiouracil

[Term]
id: ECTO:0900492
name: exposure to thyroid hormone via injection
def: "An exposure to thyroid hormone via injection route." []
synonym: "thyroid hormone exposure via injection route" EXACT []
is_a: ECTO:9001910 ! exposure to thyroid hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:60311 ! has exposure stimulus thyroid hormone
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900493
name: exposure to P2Y12 receptor antagonist via ingestion
def: "An exposure to P2Y12 receptor antagonist via ingestion route." []
synonym: "P2Y12 receptor antagonist exposure via ingestion route" EXACT []
is_a: ECTO:9001993 ! exposure to P2Y12 receptor antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:68563 ! has exposure stimulus P2Y12 receptor antagonist
relationship: RO:0002242 ExO:0000056 ! has exposure route ingestion route

[Term]
id: ECTO:0900494
name: exposure to titanium dioxide nanoparticle via ingestion
def: "An exposure to titanium dioxide nanoparticle via ingestion route." []
synonym: "titanium dioxide nanoparticle exposure via ingestion route" EXACT []
is_a: ECTO:0900375 ! exposure to nanoparticle via ingestion
is_a: ECTO:9001369 ! exposure to titanium dioxide nanoparticle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:51050 ! has exposure stimulus titanium dioxide nanoparticle

[Term]
id: ECTO:0900495
name: exposure to tofacitinib via ingestion
def: "An exposure to tofacitinib via ingestion route." []
synonym: "tofacitinib exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002645 ! exposure to tofacitinib
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:71200 ! has exposure stimulus tofacitinib

[Term]
id: ECTO:0900496
name: exposure to monosaccharide in food via ingestion
def: "An exposure to monosaccharide via ingestion route." []
synonym: "monosaccharide exposure via ingestion route" EXACT []
is_a: ECTO:0900050 ! exposure to carbohydrate via ingestion
is_a: ECTO:9000239 ! exposure to monosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35381 ! has exposure stimulus monosaccharide

[Term]
id: ECTO:0900497
name: exposure to safrole via inhalation
def: "An exposure to safrole via inhalation route." []
synonym: "safrole exposure via inhalation route" EXACT []
is_a: ECTO:9001250 ! exposure to safrole
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:8994 ! has exposure stimulus safrole
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900498
name: exposure to coniferyl aldehyde via inhalation
def: "An exposure to coniferyl aldehyde via inhalation route." []
synonym: "coniferyl aldehyde exposure via inhalation route" EXACT []
is_a: ECTO:9002307 ! exposure to coniferyl aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:16547 ! has exposure stimulus coniferyl aldehyde
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900499
name: exposure to treprostinil via injection
def: "An exposure to treprostinil via injection route." []
synonym: "treprostinil exposure via injection route" EXACT []
is_a: ECTO:9002894 ! exposure to treprostinil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:50861 ! has exposure stimulus treprostinil
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900500
name: exposure to triamcinolone acetonide via injection
def: "An exposure to triamcinolone acetonide via injection route." []
synonym: "triamcinolone acetonide exposure via injection route" EXACT []
is_a: ECTO:9002398 ! exposure to triamcinolone acetonide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:71418 ! has exposure stimulus triamcinolone acetonide
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900501
name: exposure to trimethylamine via inhalation
def: "An exposure to trimethylamine via inhalation route." []
synonym: "trimethylamine exposure via inhalation route" EXACT []
is_a: ECTO:9001512 ! exposure to trimethylamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:18139 ! has exposure stimulus trimethylamine
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900502
name: exposure to trimethylamine via ingestion
def: "An exposure to trimethylamine via ingestion route." []
synonym: "trimethylamine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9001512 ! exposure to trimethylamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18139 ! has exposure stimulus trimethylamine

[Term]
id: ECTO:0900503
name: exposure to L-lysine via ingestion
def: "An exposure to L-lysine via ingestion route." []
synonym: "L-lysine exposure via ingestion route" EXACT []
is_a: ECTO:0900521 ! exposure to lysine via ingestion
is_a: ECTO:9001315 ! exposure to L-lysine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18019 ! has exposure stimulus L-lysine

[Term]
id: ECTO:0900504
name: exposure to tropane via ingestion
def: "An exposure to tropane via ingestion route." []
synonym: "tropane exposure via ingestion route" EXACT []
is_a: ECTO:0900477 ! exposure to alkaloid via ingestion
is_a: ECTO:9000201 ! exposure to tropane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:35615 ! has exposure stimulus tropane

[Term]
id: ECTO:0900505
name: exposure to tryptophol via ingestion
def: "An exposure to tryptophol via ingestion route." []
synonym: "tryptophol exposure via ingestion route" EXACT []
is_a: ECTO:0900101 ! exposure to alcohol via ingestion
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002896 ! exposure to tryptophol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:17890 ! has exposure stimulus tryptophol

[Term]
id: ECTO:0900506
name: maternal exposure to valproate semisodium
def: "An exposure to valproate semisodium via maternal transfer." []
synonym: "valproate semisodium exposure via maternal" EXACT []
is_a: ECTO:9002239 ! exposure to valproate semisodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000159 ! has exposure route maternal
intersection_of: RO:0002309 CHEBI:4667 ! has exposure stimulus valproate semisodium
relationship: RO:0002242 ExO:0000159 ! has exposure route maternal

[Term]
id: ECTO:0900507
name: exposure to valsartan via ingestion
def: "An exposure to valsartan via ingestion route." []
synonym: "valsartan exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000903 ! exposure to valsartan
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:9927 ! has exposure stimulus valsartan

[Term]
id: ECTO:0900508
name: exposure to vancomycin via ingestion
def: "An exposure to vancomycin via ingestion route." []
synonym: "vancomycin exposure via ingestion route" EXACT []
is_a: ECTO:0900059 ! exposure to peptide via ingestion
is_a: ECTO:9002656 ! exposure to vancomycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:28001 ! has exposure stimulus vancomycin

[Term]
id: ECTO:0900509
name: exposure to vanillin via ingestion
def: "An exposure to vanillin via ingestion route." []
synonym: "vanillin exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002659 ! exposure to vanillin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18346 ! has exposure stimulus vanillin

[Term]
id: ECTO:0900510
name: exposure to warfarin via ingestion
def: "An exposure to warfarin via ingestion route." []
synonym: "warfarin exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9002158 ! exposure to warfarin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:10033 ! has exposure stimulus warfarin

[Term]
id: ECTO:0900511
name: exposure to vulnerary via injection
def: "An exposure to vulnerary via injection route." []
synonym: "vulnerary exposure via injection route" EXACT []
is_a: ECTO:9002016 ! exposure to vulnerary
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:73336 ! has exposure stimulus vulnerary
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900512
name: exposure to pirinixic acid via injection
def: "An exposure to pirinixic acid via injection route." []
synonym: "pirinixic acid exposure via injection route" EXACT []
is_a: ECTO:9002906 ! exposure to pirinixic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000060 ! has exposure route injection route
intersection_of: RO:0002309 CHEBI:32509 ! has exposure stimulus pirinixic acid
relationship: RO:0002242 ExO:0000060 ! has exposure route injection route

[Term]
id: ECTO:0900513
name: exposure to ximelagatran via ingestion
def: "An exposure to ximelagatran via ingestion route." []
synonym: "ximelagatran exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000263 ! exposure to ximelagatran
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:65172 ! has exposure stimulus ximelagatran

[Term]
id: ECTO:0900514
name: exposure to xylose via ingestion
def: "An exposure to xylose via ingestion route." []
synonym: "xylose exposure via ingestion route" EXACT []
is_a: ECTO:0900496 ! exposure to monosaccharide in food via ingestion
is_a: ECTO:9002864 ! exposure to xylose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:18222 ! has exposure stimulus xylose

[Term]
id: ECTO:0900515
name: exposure to CHZ868 via ingestion
def: "An exposure to CHZ868 via ingestion route." []
synonym: "CHZ868 exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002291 ! exposure to CHZ868
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:90828 ! has exposure stimulus CHZ868

[Term]
id: ECTO:0900516
name: exposure to ziprasidone via ingestion
def: "An exposure to ziprasidone via ingestion route." []
synonym: "ziprasidone exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9000358 ! exposure to ziprasidone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:10119 ! has exposure stimulus ziprasidone

[Term]
id: ECTO:0900517
name: exposure to zinc oxide via ingestion
def: "An exposure to zinc oxide via ingestion route." []
synonym: "zinc oxide exposure via ingestion route" EXACT []
is_a: ECTO:0900042 ! exposure to chemical entity via ingestion
is_a: ECTO:9001519 ! exposure to zinc oxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:36560 ! has exposure stimulus zinc oxide

[Term]
id: ECTO:0900518
name: exposure to alpha-tocopherol via ingestion
def: "An exposure to alpha-tocopherol via ingestion route." []
synonym: "alpha-tocopherol exposure via ingestion route" EXACT []
is_a: ECTO:0900026 ! exposure to vitamin E via ingestion
is_a: ECTO:9001341 ! exposure to alpha-tocopherol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:22470 ! has exposure stimulus alpha-tocopherol

[Term]
id: ECTO:0900519
name: exposure to beta-Glcp-(1->6)-\{beta-Glcp-(1->6)-\{[beta-Glcp-(1->3)]5\}-[beta-Glcp-(1->3)]5\}-[beta-Glcp-(1->3)]4-beta-Glcp via ingestion
def: "An exposure to beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp via ingestion route." []
synonym: "beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp exposure via ingestion route" EXACT []
is_a: ECTO:0900055 ! exposure to polysaccharide via ingestion
is_a: ECTO:9002361 ! exposure to beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:62319 ! has exposure stimulus beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp

[Term]
id: ECTO:0900520
name: exposure to cannabinoid receptor agonist via inhalation
def: "An exposure to cannabinoid receptor agonist via inhalation route." []
synonym: "cannabinoid receptor agonist exposure via inhalation route" EXACT []
is_a: ECTO:9001981 ! exposure to cannabinoid receptor agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000057 ! has exposure route inhalation route
intersection_of: RO:0002309 CHEBI:67072 ! has exposure stimulus cannabinoid receptor agonist
relationship: RO:0002242 ExO:0000057 ! has exposure route inhalation route

[Term]
id: ECTO:0900521
name: exposure to lysine via ingestion
def: "An exposure to lysine via ingestion route." []
synonym: "lysine exposure via ingestion route" EXACT []
is_a: ECTO:0900407 ! exposure to organonitrogen compound via ingestion
is_a: ECTO:9002767 ! exposure to lysine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002242 ExO:0000056 ! has exposure route ingestion route
intersection_of: RO:0002309 CHEBI:25094 ! has exposure stimulus lysine

[Term]
id: ECTO:1000000
name: exposure to environmental condition
def: "A exposure event involving the interaction of an exposure receptor to the condition of environmental condition." []
synonym: "environmental condition exposure" EXACT []
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000203 ! has exposure stimulus environmental condition
relationship: RO:0002309 ENVO:01000203 ! has exposure stimulus environmental condition

[Term]
id: ECTO:1000001
name: exposure to coal power plant
def: "A exposure event involving the interaction of an exposure receptor to coal power plant." []
synonym: "coal power plant exposure" EXACT []
is_a: ECTO:1000002 ! exposure to fossil fuel power plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:2000038 ! has exposure stimulus coal power plant
relationship: RO:0002309 ENVO:2000038 ! has exposure stimulus coal power plant

[Term]
id: ECTO:1000002
name: exposure to fossil fuel power plant
def: "A exposure event involving the interaction of an exposure receptor to fossil fuel power plant." []
synonym: "fossil fuel power plant exposure" EXACT []
is_a: ECTO:1000009 ! exposure to power plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:2000037 ! has exposure stimulus fossil fuel power plant
relationship: RO:0002309 ENVO:2000037 ! has exposure stimulus fossil fuel power plant

[Term]
id: ECTO:1000003
name: exposure to mine
def: "A exposure event involving the interaction of an exposure receptor to mine." []
synonym: "mine exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00000076 ! has exposure stimulus mine
relationship: RO:0002309 ENVO:00000076 ! has exposure stimulus mine

[Term]
id: ECTO:1000004
name: exposure to wooden building floor
def: "A exposure event involving the interaction of an exposure receptor to wooden building floor." []
synonym: "wooden building floor exposure" EXACT []
is_a: ECTO:0400000 ! exposure to environmental layer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000488 ! has exposure stimulus wooden building floor
relationship: RO:0002309 ENVO:01000488 ! has exposure stimulus wooden building floor

[Term]
id: ECTO:1000005
name: exposure to concrete building floor
def: "A exposure event involving the interaction of an exposure receptor to concrete building floor." []
synonym: "concrete building floor exposure" EXACT []
is_a: ECTO:0400000 ! exposure to environmental layer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000489 ! has exposure stimulus concrete building floor
relationship: RO:0002309 ENVO:01000489 ! has exposure stimulus concrete building floor

[Term]
id: ECTO:1000006
name: exposure to radiation shielding disposition
def: "A exposure event involving the interaction of an exposure receptor to radiation shielding disposition." []
synonym: "radiation shielding disposition exposure" EXACT []
is_a: ECTO:0500000 ! exposure to environmental disposition
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001195 ! has exposure stimulus radiation shielding disposition
relationship: RO:0002309 ENVO:01001195 ! has exposure stimulus radiation shielding disposition

[Term]
id: ECTO:1000007
name: exposure to high temperature environment
def: "A exposure event involving the interaction of an exposure receptor to high temperature environment." []
synonym: "high temperature environment exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000305 ! has exposure stimulus high temperature environment
relationship: RO:0002309 ENVO:01000305 ! has exposure stimulus high temperature environment

[Term]
id: ECTO:1000008
name: exposure to gas power station
def: "A exposure event involving the interaction of an exposure receptor to gas power station." []
synonym: "gas power station exposure" EXACT []
is_a: ECTO:1000002 ! exposure to fossil fuel power plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:2000039 ! has exposure stimulus gas power station
relationship: RO:0002309 ENVO:2000039 ! has exposure stimulus gas power station

[Term]
id: ECTO:1000009
name: exposure to power plant
def: "A exposure event involving the interaction of an exposure receptor to power plant." []
synonym: "power plant exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002214 ! has exposure stimulus power plant
relationship: RO:0002309 ENVO:00002214 ! has exposure stimulus power plant

[Term]
id: ECTO:1000010
name: exposure to geothermal power plant
def: "A exposure event involving the interaction of an exposure receptor to geothermal power plant." []
synonym: "geothermal power plant exposure" EXACT []
is_a: ECTO:1000009 ! exposure to power plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002215 ! has exposure stimulus geothermal power plant
relationship: RO:0002309 ENVO:00002215 ! has exposure stimulus geothermal power plant

[Term]
id: ECTO:1000011
name: exposure to nuclear power plant
def: "A exposure event involving the interaction of an exposure receptor to nuclear power plant." []
synonym: "nuclear power plant exposure" EXACT []
is_a: ECTO:1000009 ! exposure to power plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002271 ! has exposure stimulus nuclear power plant
relationship: RO:0002309 ENVO:00002271 ! has exposure stimulus nuclear power plant

[Term]
id: ECTO:1000012
name: exposure to solar power station
def: "A exposure event involving the interaction of an exposure receptor to solar power station." []
synonym: "solar power station exposure" EXACT []
is_a: ECTO:1000009 ! exposure to power plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:2000041 ! has exposure stimulus solar power station
relationship: RO:0002309 ENVO:2000041 ! has exposure stimulus solar power station

[Term]
id: ECTO:1000013
name: exposure to factory
def: "A exposure event involving the interaction of an exposure receptor to factory." []
synonym: "factory exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000536 ! has exposure stimulus factory
relationship: RO:0002309 ENVO:01000536 ! has exposure stimulus factory

[Term]
id: ECTO:1000014
name: exposure to waste treatment plant
def: "A exposure event involving the interaction of an exposure receptor to waste treatment plant." []
synonym: "waste treatment plant exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002272 ! has exposure stimulus waste treatment plant
relationship: RO:0002309 ENVO:00002272 ! has exposure stimulus waste treatment plant

[Term]
id: ECTO:1000015
name: exposure to wastewater treatment plant
def: "A exposure event involving the interaction of an exposure receptor to wastewater treatment plant." []
synonym: "wastewater treatment plant exposure" EXACT []
is_a: ECTO:1000014 ! exposure to waste treatment plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002043 ! has exposure stimulus wastewater treatment plant
relationship: RO:0002309 ENVO:00002043 ! has exposure stimulus wastewater treatment plant

[Term]
id: ECTO:1000016
name: exposure to agricultural wastewater treatment plant
def: "A exposure event involving the interaction of an exposure receptor to agricultural wastewater treatment plant." []
synonym: "agricultural wastewater treatment plant exposure" EXACT []
is_a: ECTO:1000015 ! exposure to wastewater treatment plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:2000003 ! has exposure stimulus agricultural wastewater treatment plant
relationship: RO:0002309 ENVO:2000003 ! has exposure stimulus agricultural wastewater treatment plant

[Term]
id: ECTO:1000017
name: exposure to industrial wastewater treatment plant
def: "A exposure event involving the interaction of an exposure receptor to industrial wastewate treatment plant." []
synonym: "industrial wastewate treatment plant exposure" EXACT []
is_a: ECTO:1000015 ! exposure to wastewater treatment plant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:2000002 ! has exposure stimulus industrial wastewate treatment plant
relationship: RO:0002309 ENVO:2000002 ! has exposure stimulus industrial wastewate treatment plant

[Term]
id: ECTO:1000018
name: exposure to extreme high temperature environment
def: "A exposure event involving the interaction of an exposure receptor to extreme high temperature environment." []
synonym: "extreme high temperature environment exposure" EXACT []
is_a: ECTO:1000007 ! exposure to high temperature environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000318 ! has exposure stimulus extreme high temperature environment
relationship: RO:0002309 ENVO:01000318 ! has exposure stimulus extreme high temperature environment

[Term]
id: ECTO:1000019
name: exposure to high pressure environment
def: "A exposure event involving the interaction of an exposure receptor to high pressure environment." []
synonym: "high pressure environment exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000304 ! has exposure stimulus high pressure environment
relationship: RO:0002309 ENVO:01000304 ! has exposure stimulus high pressure environment

[Term]
id: ECTO:1000020
name: exposure to weather
def: "A exposure event involving the interaction of an exposure receptor to the condition of weather." []
synonym: "weather exposure" EXACT []
is_a: ECTO:1000000 ! exposure to environmental condition
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001078 ! has exposure stimulus weather
relationship: RO:0002309 ENVO:01001078 ! has exposure stimulus weather

[Term]
id: ECTO:1000021
name: exposure to construction
def: "A exposure event involving the interaction of an exposure receptor to construction." []
synonym: "construction exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001813 ! has exposure stimulus construction
relationship: RO:0002309 ENVO:01001813 ! has exposure stimulus construction

[Term]
id: ECTO:1000022
name: exposure to storm surge
def: "A exposure event involving the interaction of an exposure receptor to storm surge." []
synonym: "storm surge exposure" EXACT []
is_a: ECTO:1000030 ! exposure to flood
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000714 ! has exposure stimulus storm surge
relationship: RO:0002309 ENVO:01000714 ! has exposure stimulus storm surge

[Term]
id: ECTO:1000023
name: exposure to icestorm
def: "A exposure event involving the interaction of an exposure receptor to icestorm." []
synonym: "icestorm exposure" EXACT []
is_a: ECTO:8000017 ! exposure to atmospheric process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000882 ! has exposure stimulus icestorm
relationship: RO:0002309 ENVO:01000882 ! has exposure stimulus icestorm

[Term]
id: ECTO:1000024
name: exposure to tornado
def: "A exposure event involving the interaction of an exposure receptor to tornado." []
synonym: "tornado exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001482 ! has exposure stimulus tornado
relationship: RO:0002309 ENVO:01001482 ! has exposure stimulus tornado

[Term]
id: ECTO:1000025
name: exposure to waterspout
def: "A exposure event involving the interaction of an exposure receptor to waterspout." []
synonym: "waterspout exposure" EXACT []
is_a: ECTO:1000024 ! exposure to tornado
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001487 ! has exposure stimulus waterspout
relationship: RO:0002309 ENVO:01001487 ! has exposure stimulus waterspout

[Term]
id: ECTO:1000026
name: exposure to flash flood
def: "A exposure event involving the interaction of an exposure receptor to flash flood." []
synonym: "flash flood exposure" EXACT []
is_a: ECTO:1000030 ! exposure to flood
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000713 ! has exposure stimulus flash flood
relationship: RO:0002309 ENVO:01000713 ! has exposure stimulus flash flood

[Term]
id: ECTO:1000027
name: exposure to rain
def: "A exposure event involving the interaction of an exposure receptor to rain." []
synonym: "rain exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001564 ! has exposure stimulus rain
relationship: RO:0002309 ENVO:01001564 ! has exposure stimulus rain

[Term]
id: ECTO:1000028
name: exposure to freezing rainfall
def: "A exposure event involving the interaction of an exposure receptor to freezing rainfall." []
synonym: "freezing rainfall exposure" EXACT []
is_a: ECTO:1000056 ! exposure to rainfall
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000896 ! has exposure stimulus freezing rainfall
relationship: RO:0002309 ENVO:01000896 ! has exposure stimulus freezing rainfall

[Term]
id: ECTO:1000029
name: exposure to thunderstorm
def: "A exposure event involving the interaction of an exposure receptor to thunderstorm." []
synonym: "thunderstorm exposure" EXACT []
is_a: ECTO:8000017 ! exposure to atmospheric process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000878 ! has exposure stimulus thunderstorm
relationship: RO:0002309 ENVO:01000878 ! has exposure stimulus thunderstorm

[Term]
id: ECTO:1000030
name: exposure to flood
def: "A exposure event involving the interaction of an exposure receptor to flood." []
synonym: "flood exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000710 ! has exposure stimulus flood
relationship: RO:0002309 ENVO:01000710 ! has exposure stimulus flood

[Term]
id: ECTO:1000031
name: exposure to tropical storm
def: "A exposure event involving the interaction of an exposure receptor to tropical storm." []
synonym: "tropical storm exposure" EXACT []
is_a: ECTO:8000017 ! exposure to atmospheric process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001296 ! has exposure stimulus tropical storm
relationship: RO:0002309 ENVO:01001296 ! has exposure stimulus tropical storm

[Term]
id: ECTO:1000032
name: exposure to air conditioning unit
def: "A exposure event involving the interaction of an exposure receptor to the condition of air conditioning unit." []
synonym: "air conditioning unit exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002874 ! has exposure stimulus air conditioning unit
relationship: RO:0002309 ENVO:00002874 ! has exposure stimulus air conditioning unit

[Term]
id: ECTO:1000033
name: exposure to abattoir
def: "A exposure event involving the interaction of an exposure receptor to abattoir." []
synonym: "abattoir exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000925 ! has exposure stimulus abattoir
relationship: RO:0002309 ENVO:01000925 ! has exposure stimulus abattoir

[Term]
id: ECTO:1000034
name: exposure to farm
def: "A exposure event involving the interaction of an exposure receptor to farm." []
synonym: "farm exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00000078 ! has exposure stimulus farm
relationship: RO:0002309 ENVO:00000078 ! has exposure stimulus farm

[Term]
id: ECTO:1000035
name: exposure to hospital
def: "A exposure event involving the interaction of an exposure receptor to hospital." []
synonym: "hospital exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002173 ! has exposure stimulus hospital
relationship: RO:0002309 ENVO:00002173 ! has exposure stimulus hospital

[Term]
id: ECTO:1000036
name: exposure to laboratory
def: "A exposure event involving the interaction of an exposure receptor to laboratory facility." []
synonym: "laboratory facility exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001406 ! has exposure stimulus laboratory facility
relationship: RO:0002309 ENVO:01001406 ! has exposure stimulus laboratory facility

[Term]
id: ECTO:1000037
name: exposure to office
def: "A exposure event involving the interaction of an exposure receptor to office." []
synonym: "office exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001224 ! has exposure stimulus office
relationship: RO:0002309 ENVO:01001224 ! has exposure stimulus office

[Term]
id: ECTO:1000040
name: exposure to restaurant
def: "A exposure event involving the interaction of an exposure receptor to restaurant." []
synonym: "restaurant exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000934 ! has exposure stimulus restaurant
relationship: RO:0002309 ENVO:01000934 ! has exposure stimulus restaurant

[Term]
id: ECTO:1000041
name: exposure to retail shop
def: "A exposure event involving the interaction of an exposure receptor to shop." []
synonym: "shop exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002221 ! has exposure stimulus shop
relationship: RO:0002309 ENVO:00002221 ! has exposure stimulus shop

[Term]
id: ECTO:1000042
name: exposure to day care building
def: "A exposure event involving the interaction of an exposure receptor to day care building." []
synonym: "day care building exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000927 ! has exposure stimulus day care building
relationship: RO:0002309 ENVO:01000927 ! has exposure stimulus day care building

[Term]
id: ECTO:1000043
name: exposure to temperature of water
def: "A exposure event involving the interaction of an exposure receptor to the condition of temperature of water." []
synonym: "temperature of water exposure" EXACT []
is_a: ECTO:0000979 ! exposure to temperature of environmental surroundings
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:09200014 ! has exposure stimulus temperature of water
relationship: RO:0002309 ENVO:09200014 ! has exposure stimulus temperature of water

[Term]
id: ECTO:1000044
name: exposure to freezing
def: "A exposure event involving the interaction of an exposure receptor to the condition of freezing." []
synonym: "freezing exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001548 ! has exposure stimulus freezing
relationship: RO:0002309 ENVO:01001548 ! has exposure stimulus freezing

[Term]
id: ECTO:1000045
name: exposure to irradiation
def: "A exposure event involving the interaction of an exposure receptor to the condition of irradiation." []
synonym: "irradiation exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01003014 ! has exposure stimulus irradiation
relationship: RO:0002309 ENVO:01003014 ! has exposure stimulus irradiation

[Term]
id: ECTO:1000046
name: exposure to high osmolarity environment
def: "A exposure event involving the interaction of an exposure receptor to the condition of high osmolarity environment." []
synonym: "high osmolarity environment exposure" EXACT []
is_a: ECTO:0600000 ! exposure to environmental system
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000314 ! has exposure stimulus high osmolarity environment
relationship: RO:0002309 ENVO:01000314 ! has exposure stimulus high osmolarity environment

[Term]
id: ECTO:1000056
name: exposure to rainfall
def: "A exposure event involving the interaction of an exposure receptor to water-based rainfall." []
synonym: "water-based rainfall exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000830 ! has exposure stimulus water-based rainfall
relationship: RO:0002309 ENVO:01000830 ! has exposure stimulus water-based rainfall

[Term]
id: ECTO:1000121
name: exposure to landspout
def: "A exposure event involving the interaction of an exposure receptor to landspout." []
synonym: "landspout exposure" EXACT []
is_a: ECTO:1000024 ! exposure to tornado
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001486 ! has exposure stimulus landspout
relationship: RO:0002309 ENVO:01001486 ! has exposure stimulus landspout

[Term]
id: ECTO:2000000
name: exposure to medical action
def: "An exposure to medical action." []
synonym: "medical action exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000001 ! has exposure stimulus medical action
relationship: RO:0002309 MAXO:0000001 ! has exposure stimulus medical action

[Term]
id: ECTO:2000001
name: exposure to medication for hypertension
def: "An exposure to pulmonary antihypertensive agent therapy." []
synonym: "pulmonary antihypertensive agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000321 ! has exposure stimulus pulmonary antihypertensive agent therapy
relationship: RO:0002309 MAXO:0000321 ! has exposure stimulus pulmonary antihypertensive agent therapy

[Term]
id: ECTO:2000002
name: exposure to dyslipidemic agent therapy
def: "An exposure to dyslipidemic agent therapy." []
synonym: "dyslipidemic agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000189 ! has exposure stimulus dyslipidemic agent therapy
relationship: RO:0002309 MAXO:0000189 ! has exposure stimulus dyslipidemic agent therapy

[Term]
id: ECTO:2000003
name: exposure to blood glucose regulator therapy
def: "An exposure to blood glucose regulator therapy." []
synonym: "blood glucose regulator therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000175 ! has exposure stimulus blood glucose regulator therapy
relationship: RO:0002309 MAXO:0000175 ! has exposure stimulus blood glucose regulator therapy

[Term]
id: ECTO:2000004
name: exposure to theraputic insulin treatment
def: "An exposure to insulin treatment." []
synonym: "insulin treatment exposure" EXACT []
is_a: ECTO:2000035 ! exposure to glycemic agents
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000259 ! has exposure stimulus insulin treatment
relationship: RO:0002309 MAXO:0000259 ! has exposure stimulus insulin treatment

[Term]
id: ECTO:2000005
name: exposure to hormone replacement therapy
def: "An exposure to sex hormone modifying agent therapy." []
synonym: "sex hormone modifying agent therapy exposure" EXACT []
is_a: ECTO:2000074 ! exposure to hormone modifying therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000282 ! has exposure stimulus sex hormone modifying agent therapy
relationship: RO:0002309 MAXO:0000282 ! has exposure stimulus sex hormone modifying agent therapy

[Term]
id: ECTO:2000006
name: exposure to estrogen modification therapy
def: "An exposure to estrogen modifying agent therapy." []
synonym: "estrogen modifying agent therapy exposure" EXACT []
is_a: ECTO:2000077 ! exposure to menopausal hormone therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000287 ! has exposure stimulus estrogen modifying agent therapy
relationship: RO:0002309 MAXO:0000287 ! has exposure stimulus estrogen modifying agent therapy

[Term]
id: ECTO:2000007
name: exposure to platelet aggregation inhibitors
def: "An exposure to platelet aggregation inhibitor therapy." []
synonym: "platelet aggregation inhibitor therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000180 ! has exposure stimulus platelet aggregation inhibitor therapy
relationship: RO:0002309 MAXO:0000180 ! has exposure stimulus platelet aggregation inhibitor therapy

[Term]
id: ECTO:2000008
name: exposure to antiarrythmic agents
def: "An exposure to antiarrythmic agent therapy." []
synonym: "antiarrythmic agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000185 ! has exposure stimulus antiarrythmic agent therapy
relationship: RO:0002309 MAXO:0000185 ! has exposure stimulus antiarrythmic agent therapy

[Term]
id: ECTO:2000009
name: exposure to antipsychotic medication
def: "An exposure to antipsychotic agent therapy." []
synonym: "antipsychotic agent therapy exposure" EXACT []
is_a: ECTO:2000031 ! exposure to theraputic tranquilizers
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000166 ! has exposure stimulus antipsychotic agent therapy
relationship: RO:0002309 MAXO:0000166 ! has exposure stimulus antipsychotic agent therapy

[Term]
id: ECTO:2000010
name: exposure to calcium channel blocker treatment
def: "An exposure to calcium channel blocking agent therapy." []
synonym: "calcium channel blocking agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000434 ! has exposure stimulus calcium channel blocking agent therapy
relationship: RO:0002309 MAXO:0000434 ! has exposure stimulus calcium channel blocking agent therapy

[Term]
id: ECTO:2000011
name: exposure to NSAIDs
def: "An exposure to NSAID therapy." []
synonym: "NSAID therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000221 ! has exposure stimulus NSAID therapy
relationship: RO:0002309 MAXO:0000221 ! has exposure stimulus NSAID therapy

[Term]
id: ECTO:2000012
name: exposure to H2 blockers
def: "An exposure to H2-receptor antagonist agent therapy." []
synonym: "H2-receptor antagonist agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000269 ! has exposure stimulus H2-receptor antagonist agent therapy
relationship: RO:0002309 MAXO:0000269 ! has exposure stimulus H2-receptor antagonist agent therapy

[Term]
id: ECTO:2000013
name: exposure to theraputic diuretics
def: "An exposure to diuretic agent therapy." []
synonym: "diuretic agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000165 ! has exposure stimulus diuretic agent therapy
relationship: RO:0002309 MAXO:0000165 ! has exposure stimulus diuretic agent therapy

[Term]
id: ECTO:2000014
name: exposure to anticholinergic bronchodilators
def: "An exposure to anticholinergic bronchodilator agent therapy." []
synonym: "anticholinergic bronchodilator agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000317 ! has exposure stimulus anticholinergic bronchodilator agent therapy
relationship: RO:0002309 MAXO:0000317 ! has exposure stimulus anticholinergic bronchodilator agent therapy

[Term]
id: ECTO:2000015
name: exposure to corticosteroid therapy
def: "An exposure to corticosteroid agent therapy." []
synonym: "corticosteroid agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000640 ! has exposure stimulus corticosteroid agent therapy
relationship: RO:0002309 MAXO:0000640 ! has exposure stimulus corticosteroid agent therapy

[Term]
id: ECTO:2000016
name: exposure to MAO inhibitor
def: "An exposure to monoamine oxidase inhibitor therapy." []
synonym: "monoamine oxidase inhibitor therapy exposure" EXACT []
is_a: ECTO:2000017 ! exposure to antidepressants
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000213 ! has exposure stimulus monoamine oxidase inhibitor therapy
relationship: RO:0002309 MAXO:0000213 ! has exposure stimulus monoamine oxidase inhibitor therapy

[Term]
id: ECTO:2000017
name: exposure to antidepressants
def: "An exposure to antidepressant agent therapy." []
synonym: "antidepressant agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000160 ! has exposure stimulus antidepressant agent therapy
relationship: RO:0002309 MAXO:0000160 ! has exposure stimulus antidepressant agent therapy

[Term]
id: ECTO:2000018
name: exposure to phosphodiesterase inhibitors
def: "An exposure to phosphodiesterase inhibitor bronchodilator agent therapy." []
synonym: "phosphodiesterase inhibitor bronchodilator agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000318 ! has exposure stimulus phosphodiesterase inhibitor bronchodilator agent therapy
relationship: RO:0002309 MAXO:0000318 ! has exposure stimulus phosphodiesterase inhibitor bronchodilator agent therapy

[Term]
id: ECTO:2000019
name: exposure to proton pump inhibitors
def: "An exposure to proton pump inhibitor agent therapy." []
synonym: "proton pump inhibitor agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000272 ! has exposure stimulus proton pump inhibitor agent therapy
relationship: RO:0002309 MAXO:0000272 ! has exposure stimulus proton pump inhibitor agent therapy

[Term]
id: ECTO:2000020
name: exposure to progestin treatment
def: "An exposure to progestin modifying agent therapy." []
synonym: "progestin modifying agent therapy exposure" EXACT []
is_a: ECTO:2000077 ! exposure to menopausal hormone therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000288 ! has exposure stimulus progestin modifying agent therapy
relationship: RO:0002309 MAXO:0000288 ! has exposure stimulus progestin modifying agent therapy

[Term]
id: ECTO:2000021
name: exposure to drugs to treat Parkinsons
def: "An exposure to antiparkinson agent therapy." []
synonym: "antiparkinson agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000157 ! has exposure stimulus antiparkinson agent therapy
relationship: RO:0002309 MAXO:0000157 ! has exposure stimulus antiparkinson agent therapy

[Term]
id: ECTO:2000022
name: exposure to vasodilators
def: "An exposure to vasodilator agent therapy." []
synonym: "vasodilator agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000191 ! has exposure stimulus vasodilator agent therapy
relationship: RO:0002309 MAXO:0000191 ! has exposure stimulus vasodilator agent therapy

[Term]
id: ECTO:2000023
name: exposure to sympathomimetic bronchodilators
def: "An exposure to sympathomimetic bronchodilator agent therapy." []
synonym: "sympathomimetic bronchodilator agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000319 ! has exposure stimulus sympathomimetic bronchodilator agent therapy
relationship: RO:0002309 MAXO:0000319 ! has exposure stimulus sympathomimetic bronchodilator agent therapy

[Term]
id: ECTO:2000024
name: exposure to tricyclic antidepressants
def: "An exposure to tricyclic antidepressant agent therapy." []
synonym: "tricyclic antidepressant agent therapy exposure" EXACT []
is_a: ECTO:2000017 ! exposure to antidepressants
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000215 ! has exposure stimulus tricyclic antidepressant agent therapy
relationship: RO:0002309 MAXO:0000215 ! has exposure stimulus tricyclic antidepressant agent therapy

[Term]
id: ECTO:2000025
name: exposure to thyroid-modifying hormonal therapy
def: "An exposure to thyroid-modifying hormonal agent therapy." []
synonym: "thyroid-modifying hormonal agent therapy exposure" EXACT []
is_a: ECTO:2000074 ! exposure to hormone modifying therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000284 ! has exposure stimulus thyroid-modifying hormonal agent therapy
relationship: RO:0002309 MAXO:0000284 ! has exposure stimulus thyroid-modifying hormonal agent therapy

[Term]
id: ECTO:2000027
name: exposure to anticoagulants
def: "An exposure to anticoagulant agent therapy." []
synonym: "anticoagulant agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000178 ! has exposure stimulus anticoagulant agent therapy
relationship: RO:0002309 MAXO:0000178 ! has exposure stimulus anticoagulant agent therapy

[Term]
id: ECTO:2000028
name: exposure to sartans
def: "An exposure to RAAS inhibitor therapy." []
synonym: "RAAS inhibitor therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000190 ! has exposure stimulus RAAS inhibitor therapy
relationship: RO:0002309 MAXO:0000190 ! has exposure stimulus RAAS inhibitor therapy

[Term]
id: ECTO:2000029
name: exposure to alpha-blockers
def: "An exposure to alpha adrenergic antagonist therapy." []
synonym: "alpha adrenergic antagonist therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000184 ! has exposure stimulus alpha adrenergic antagonist therapy
relationship: RO:0002309 MAXO:0000184 ! has exposure stimulus alpha adrenergic antagonist therapy

[Term]
id: ECTO:2000030
name: exposure to cholinesterase inhibitor
def: "An exposure to cholinesteriase inhibitor therapy." []
synonym: "cholinesteriase inhibitor therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000210 ! has exposure stimulus cholinesteriase inhibitor therapy
relationship: RO:0002309 MAXO:0000210 ! has exposure stimulus cholinesteriase inhibitor therapy

[Term]
id: ECTO:2000031
name: exposure to theraputic tranquilizers
def: "An exposure to mood and behavior-altering agent therapy." []
synonym: "mood and behavior-altering agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000023 ! has exposure stimulus mood and behavior-altering agent therapy
relationship: RO:0002309 MAXO:0000023 ! has exposure stimulus mood and behavior-altering agent therapy

[Term]
id: ECTO:2000032
name: exposure to beta-blockers
def: "An exposure to beta-adrenergic antagonist therapy." []
synonym: "beta-adrenergic antagonist therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000187 ! has exposure stimulus beta-adrenergic antagonist therapy
relationship: RO:0002309 MAXO:0000187 ! has exposure stimulus beta-adrenergic antagonist therapy

[Term]
id: ECTO:2000034
name: exposure to antileukotriene agents
def: "An exposure to antileukotriene agent therapy." []
synonym: "antileukotriene agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000315 ! has exposure stimulus antileukotriene agent therapy
relationship: RO:0002309 MAXO:0000315 ! has exposure stimulus antileukotriene agent therapy

[Term]
id: ECTO:2000035
name: exposure to glycemic agents
def: "An exposure to glycemic agent therapy." []
synonym: "glycemic agent therapy exposure" EXACT []
is_a: ECTO:2000003 ! exposure to blood glucose regulator therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000258 ! has exposure stimulus glycemic agent therapy
relationship: RO:0002309 MAXO:0000258 ! has exposure stimulus glycemic agent therapy

[Term]
id: ECTO:2000036
name: exposure to antigout agent
def: "An exposure to uricosuric agent therapy." []
synonym: "uricosuric agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000164 ! has exposure stimulus uricosuric agent therapy
relationship: RO:0002309 MAXO:0000164 ! has exposure stimulus uricosuric agent therapy

[Term]
id: ECTO:2000037
name: exposure to diagnostic imaging
def: "An exposure to Diagnostic Imaging Testing." []
synonym: "Diagnostic Imaging Testing exposure" EXACT []
is_a: ECTO:6000024 ! exposure to clinical or research activity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C16502 ! has exposure stimulus Diagnostic Imaging Testing
relationship: RO:0002309 NCIT:C16502 ! has exposure stimulus Diagnostic Imaging Testing

[Term]
id: ECTO:2000038
name: exposure to ultrasound tomography
def: "An exposure to Ultrasound Tomography." []
synonym: "Ultrasound Tomography exposure" EXACT []
is_a: ECTO:2000037 ! exposure to diagnostic imaging
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C116448 ! has exposure stimulus Ultrasound Tomography
relationship: RO:0002309 NCIT:C116448 ! has exposure stimulus Ultrasound Tomography

[Term]
id: ECTO:2000039
name: exposure to positron emission tomography
def: "An exposure to Positron Emission Tomography." []
synonym: "Positron Emission Tomography exposure" EXACT []
is_a: ECTO:6000024 ! exposure to clinical or research activity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17007 ! has exposure stimulus Positron Emission Tomography
relationship: RO:0002309 NCIT:C17007 ! has exposure stimulus Positron Emission Tomography

[Term]
id: ECTO:2000040
name: exposure to radiography
def: "An exposure to X-Ray Imaging." []
synonym: "X-Ray Imaging exposure" EXACT []
is_a: ECTO:2000037 ! exposure to diagnostic imaging
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C38101 ! has exposure stimulus X-Ray Imaging
relationship: RO:0002309 NCIT:C38101 ! has exposure stimulus X-Ray Imaging

[Term]
id: ECTO:2000041
name: exposure to mammography
def: "An exposure to Mammography." []
synonym: "Mammography exposure" EXACT []
is_a: ECTO:2000037 ! exposure to diagnostic imaging
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C16818 ! has exposure stimulus Mammography
relationship: RO:0002309 NCIT:C16818 ! has exposure stimulus Mammography

[Term]
id: ECTO:2000042
name: exposure to xeroradiography
def: "An exposure to Xeroradiography." []
synonym: "Xeroradiography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17263 ! has exposure stimulus Xeroradiography
relationship: RO:0002309 NCIT:C17263 ! has exposure stimulus Xeroradiography

[Term]
id: ECTO:2000043
name: exposure to myelography
def: "An exposure to Myelography." []
synonym: "Myelography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C20175 ! has exposure stimulus Myelography
relationship: RO:0002309 NCIT:C20175 ! has exposure stimulus Myelography

[Term]
id: ECTO:2000044
name: exposure to bronchography
def: "An exposure to Bronchography." []
synonym: "Bronchography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C38040 ! has exposure stimulus Bronchography
relationship: RO:0002309 NCIT:C38040 ! has exposure stimulus Bronchography

[Term]
id: ECTO:2000045
name: exposure to cystography
def: "An exposure to Cystography." []
synonym: "Cystography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C38049 ! has exposure stimulus Cystography
relationship: RO:0002309 NCIT:C38049 ! has exposure stimulus Cystography

[Term]
id: ECTO:2000046
name: exposure to vaginography
def: "An exposure to Vaginography." []
synonym: "Vaginography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C38096 ! has exposure stimulus Vaginography
relationship: RO:0002309 NCIT:C38096 ! has exposure stimulus Vaginography

[Term]
id: ECTO:2000047
name: exposure to abdominal radiography
def: "An exposure to Abdominal Radiography." []
synonym: "Abdominal Radiography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C38102 ! has exposure stimulus Abdominal Radiography
relationship: RO:0002309 NCIT:C38102 ! has exposure stimulus Abdominal Radiography

[Term]
id: ECTO:2000048
name: exposure to chest radiography
def: "An exposure to Chest Radiography." []
synonym: "Chest Radiography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C38103 ! has exposure stimulus Chest Radiography
relationship: RO:0002309 NCIT:C38103 ! has exposure stimulus Chest Radiography

[Term]
id: ECTO:2000049
name: exposure to cholangiography
def: "An exposure to Cholangiography." []
synonym: "Cholangiography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C61508 ! has exposure stimulus Cholangiography
relationship: RO:0002309 NCIT:C61508 ! has exposure stimulus Cholangiography

[Term]
id: ECTO:2000050
name: exposure to total body radiography
def: "An exposure to Total Body Radiography." []
synonym: "Total Body Radiography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C96640 ! has exposure stimulus Total Body Radiography
relationship: RO:0002309 NCIT:C96640 ! has exposure stimulus Total Body Radiography

[Term]
id: ECTO:2000051
name: exposure to angiography
def: "An exposure to X-ray Angiography." []
synonym: "X-ray Angiography exposure" EXACT []
is_a: ECTO:2000040 ! exposure to radiography
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C20080 ! has exposure stimulus X-ray Angiography
relationship: RO:0002309 NCIT:C20080 ! has exposure stimulus X-ray Angiography

[Term]
id: ECTO:2000052
name: exposure to radioactivity
def: "An exposure to Radioactivity." []
synonym: "Radioactivity exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17054 ! has exposure stimulus Radioactivity
relationship: RO:0002309 NCIT:C17054 ! has exposure stimulus Radioactivity

[Term]
id: ECTO:2000053
name: exposure to Human Papillomavirus Infection
def: "An exposure to Human Papillomavirus Infection." []
synonym: "Human Papillomavirus Infection exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C27851 ! has exposure stimulus Human Papillomavirus Infection
relationship: RO:0002309 NCIT:C27851 ! has exposure stimulus Human Papillomavirus Infection

[Term]
id: ECTO:2000054
name: exposure to surgery
def: "An exposure to surgical procedure." []
synonym: "surgical procedure exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000004 ! has exposure stimulus surgical procedure
relationship: RO:0002309 MAXO:0000004 ! has exposure stimulus surgical procedure

[Term]
id: ECTO:2000055
name: exposure to kidney implantation
def: "An exposure to whole kidney transplantation." []
synonym: "whole kidney transplantation exposure" EXACT []
is_a: ECTO:2000056 ! exposure to transplant surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010043 ! has exposure stimulus whole kidney transplantation
relationship: RO:0002309 MAXO:0010043 ! has exposure stimulus whole kidney transplantation

[Term]
id: ECTO:2000056
name: exposure to transplant surgery
def: "An exposure to transplantation procedure." []
synonym: "transplantation procedure exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000068 ! has exposure stimulus transplantation procedure
relationship: RO:0002309 MAXO:0000068 ! has exposure stimulus transplantation procedure

[Term]
id: ECTO:2000057
name: exposure to pharmacotherapy
def: "An exposure to pharmacotherapy." []
synonym: "pharmacotherapy exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000058 ! has exposure stimulus pharmacotherapy
relationship: RO:0002309 MAXO:0000058 ! has exposure stimulus pharmacotherapy

[Term]
id: ECTO:2000058
name: exposure to blood transfusion
def: "An exposure to blood transfusion." []
synonym: "blood transfusion exposure" EXACT []
is_a: ECTO:2000056 ! exposure to transplant surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000756 ! has exposure stimulus blood transfusion
relationship: RO:0002309 MAXO:0000756 ! has exposure stimulus blood transfusion

[Term]
id: ECTO:2000059
name: exposure to anesthetics
def: "An exposure to anesthetic agent therapy." []
synonym: "anesthetic agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000170 ! has exposure stimulus anesthetic agent therapy
relationship: RO:0002309 MAXO:0000170 ! has exposure stimulus anesthetic agent therapy

[Term]
id: ECTO:2000060
name: exposure to neck radiograph procedure
def: "An exposure to neck radiograph procedure." []
synonym: "neck radiograph procedure exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010355 ! has exposure stimulus neck radiograph procedure
relationship: RO:0002309 MAXO:0010355 ! has exposure stimulus neck radiograph procedure

[Term]
id: ECTO:2000061
name: exposure to cephalosporin agent therapy
def: "An exposure to cephalosporin agent therapy." []
synonym: "cephalosporin agent therapy exposure" EXACT []
is_a: ECTO:2000082 ! exposure to antibacterial agent therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000197 ! has exposure stimulus cephalosporin agent therapy
relationship: RO:0002309 MAXO:0000197 ! has exposure stimulus cephalosporin agent therapy

[Term]
id: ECTO:2000062
name: exposure to antiretroviral therapy
def: "An exposure to antiretroviral therapy." []
synonym: "antiretroviral therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000573 ! has exposure stimulus antiretroviral therapy
relationship: RO:0002309 MAXO:0000573 ! has exposure stimulus antiretroviral therapy

[Term]
id: ECTO:2000063
name: exposure to arginine supplementation
def: "An exposure to arginine supplementation." []
synonym: "arginine supplementation exposure" EXACT []
is_a: ECTO:2000085 ! exposure to amino acid supplementation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010009 ! has exposure stimulus arginine supplementation
relationship: RO:0002309 MAXO:0010009 ! has exposure stimulus arginine supplementation

[Term]
id: ECTO:2000064
name: exposure to immune stimulant agent therapy
def: "An exposure to immune stimulant agent therapy." []
synonym: "immune stimulant agent therapy exposure" EXACT []
is_a: ECTO:2000124 ! exposure to immunological agent therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000296 ! has exposure stimulus immune stimulant agent therapy
relationship: RO:0002309 MAXO:0000296 ! has exposure stimulus immune stimulant agent therapy

[Term]
id: ECTO:2000065
name: exposure to calorie restrictive diet intake
def: "An exposure to calorie restrictive diet intake." []
synonym: "calorie restrictive diet intake exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000089 ! has exposure stimulus calorie restrictive diet intake
relationship: RO:0002309 MAXO:0000089 ! has exposure stimulus calorie restrictive diet intake

[Term]
id: ECTO:2000066
name: exposure to chemotherapy
def: "An exposure to chemotherapy." []
synonym: "chemotherapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000647 ! has exposure stimulus chemotherapy
relationship: RO:0002309 MAXO:0000647 ! has exposure stimulus chemotherapy

[Term]
id: ECTO:2000067
name: exposure to cancer chemotherapy
def: "An exposure to cancer chemotherapy." []
synonym: "cancer chemotherapy exposure" EXACT []
is_a: ECTO:2000066 ! exposure to chemotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000646 ! has exposure stimulus cancer chemotherapy
relationship: RO:0002309 MAXO:0000646 ! has exposure stimulus cancer chemotherapy

[Term]
id: ECTO:2000068
name: exposure to dietary intervention
def: "An exposure to dietary intervention." []
synonym: "dietary intervention exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000088 ! has exposure stimulus dietary intervention
relationship: RO:0002309 MAXO:0000088 ! has exposure stimulus dietary intervention

[Term]
id: ECTO:2000069
name: exposure to non-nucleoside reverse transcriptase inhibitor therapy
def: "An exposure to non-nucleoside reverse transcriptase inhibitor therapy." []
synonym: "non-nucleoside reverse transcriptase inhibitor therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000250 ! has exposure stimulus non-nucleoside reverse transcriptase inhibitor therapy
relationship: RO:0002309 MAXO:0000250 ! has exposure stimulus non-nucleoside reverse transcriptase inhibitor therapy

[Term]
id: ECTO:2000070
name: exposure to external beam radiation therapy
def: "An exposure to external beam radiation therapy." []
synonym: "external beam radiation therapy exposure" EXACT []
is_a: ECTO:2000079 ! exposure to radiation therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000429 ! has exposure stimulus external beam radiation therapy
relationship: RO:0002309 MAXO:0000429 ! has exposure stimulus external beam radiation therapy

[Term]
id: ECTO:2000071
name: exposure to fecal microbiota transplantation
def: "An exposure to fecal microbiota transplantation." []
synonym: "fecal microbiota transplantation exposure" EXACT []
is_a: ECTO:2000056 ! exposure to transplant surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000748 ! has exposure stimulus fecal microbiota transplantation
relationship: RO:0002309 MAXO:0000748 ! has exposure stimulus fecal microbiota transplantation

[Term]
id: ECTO:2000072
name: exposure to hepatectomy
def: "An exposure to hepatectomy." []
synonym: "hepatectomy exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001056 ! has exposure stimulus hepatectomy
relationship: RO:0002309 MAXO:0001056 ! has exposure stimulus hepatectomy

[Term]
id: ECTO:2000073
name: exposure to high fat diet intake
def: "An exposure to high fat diet intake." []
synonym: "high fat diet intake exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001547 ! has exposure stimulus high fat diet intake
relationship: RO:0002309 MAXO:0001547 ! has exposure stimulus high fat diet intake

[Term]
id: ECTO:2000074
name: exposure to hormone modifying therapy
def: "An exposure to hormone modifying therapy." []
synonym: "hormone modifying therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000283 ! has exposure stimulus hormone modifying therapy
relationship: RO:0002309 MAXO:0000283 ! has exposure stimulus hormone modifying therapy

[Term]
id: ECTO:2000075
name: exposure to dietary lysine intake avoidance
def: "An exposure to dietary lysine intake avoidance." []
synonym: "dietary lysine intake avoidance exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010091 ! has exposure stimulus dietary lysine intake avoidance
relationship: RO:0002309 MAXO:0010091 ! has exposure stimulus dietary lysine intake avoidance

[Term]
id: ECTO:2000076
name: exposure to pregnancy diet intake
def: "An exposure to pregnancy diet intake." []
synonym: "pregnancy diet intake exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000799 ! has exposure stimulus pregnancy diet intake
relationship: RO:0002309 MAXO:0000799 ! has exposure stimulus pregnancy diet intake

[Term]
id: ECTO:2000077
name: exposure to menopausal hormone therapy
def: "An exposure to menopausal hormone therapy." []
synonym: "menopausal hormone therapy exposure" EXACT []
is_a: ECTO:2000005 ! exposure to hormone replacement therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000744 ! has exposure stimulus menopausal hormone therapy
relationship: RO:0002309 MAXO:0000744 ! has exposure stimulus menopausal hormone therapy

[Term]
id: ECTO:2000078
name: exposure to nucleoside and nucleotide reverse transcriptase inhibitor therapy
def: "An exposure to nucleoside and nucleotide reverse transcriptase inhibitor therapy." []
synonym: "nucleoside and nucleotide reverse transcriptase inhibitor therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000251 ! has exposure stimulus nucleoside and nucleotide reverse transcriptase inhibitor therapy
relationship: RO:0002309 MAXO:0000251 ! has exposure stimulus nucleoside and nucleotide reverse transcriptase inhibitor therapy

[Term]
id: ECTO:2000079
name: exposure to radiation therapy
def: "An exposure to radiation therapy." []
synonym: "radiation therapy exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000014 ! has exposure stimulus radiation therapy
relationship: RO:0002309 MAXO:0000014 ! has exposure stimulus radiation therapy

[Term]
id: ECTO:2000080
name: exposure to chenodeoxycholic acid supplementation
def: "An exposure to chenodeoxycholic acid supplementation." []
synonym: "chenodeoxycholic acid supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010011 ! has exposure stimulus chenodeoxycholic acid supplementation
relationship: RO:0002309 MAXO:0010011 ! has exposure stimulus chenodeoxycholic acid supplementation

[Term]
id: ECTO:2000081
name: exposure to thiazide diuretic agent therapy
def: "An exposure to thiazide diuretic agent therapy." []
synonym: "thiazide diuretic agent therapy exposure" EXACT []
is_a: ECTO:2000013 ! exposure to theraputic diuretics
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000742 ! has exposure stimulus thiazide diuretic agent therapy
relationship: RO:0002309 MAXO:0000742 ! has exposure stimulus thiazide diuretic agent therapy

[Term]
id: ECTO:2000082
name: exposure to antibacterial agent therapy
def: "An exposure to antibacterial agent therapy." []
synonym: "antibacterial agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000061 ! has exposure stimulus antibacterial agent therapy
relationship: RO:0002309 MAXO:0000061 ! has exposure stimulus antibacterial agent therapy

[Term]
id: ECTO:2000083
name: exposure to ACE inhibitor therapy
def: "An exposure to ACE inhibitor therapy." []
synonym: "ACE inhibitor therapy exposure" EXACT []
is_a: ECTO:2000022 ! exposure to vasodilators
is_a: ECTO:2000028 ! exposure to sartans
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000652 ! has exposure stimulus ACE inhibitor therapy
relationship: RO:0002309 MAXO:0000652 ! has exposure stimulus ACE inhibitor therapy

[Term]
id: ECTO:2000084
name: exposure to aerobic exercise therapy
def: "An exposure to aerobic exercise therapy." []
synonym: "aerobic exercise therapy exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000065 ! has exposure stimulus aerobic exercise therapy
relationship: RO:0002309 MAXO:0000065 ! has exposure stimulus aerobic exercise therapy

[Term]
id: ECTO:2000085
name: exposure to amino acid supplementation
def: "An exposure to amino acid supplementation." []
synonym: "amino acid supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010020 ! has exposure stimulus amino acid supplementation
relationship: RO:0002309 MAXO:0010020 ! has exposure stimulus amino acid supplementation

[Term]
id: ECTO:2000086
name: exposure to amphetamine agent therapy
def: "An exposure to amphetamine agent therapy." []
synonym: "amphetamine agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000261 ! has exposure stimulus amphetamine agent therapy
relationship: RO:0002309 MAXO:0000261 ! has exposure stimulus amphetamine agent therapy

[Term]
id: ECTO:2000087
name: exposure to atypical antipsychotic agent therapy
def: "An exposure to atypical antipsychotic agent therapy." []
synonym: "atypical antipsychotic agent therapy exposure" EXACT []
is_a: ECTO:2000009 ! exposure to antipsychotic medication
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000243 ! has exposure stimulus atypical antipsychotic agent therapy
relationship: RO:0002309 MAXO:0000243 ! has exposure stimulus atypical antipsychotic agent therapy

[Term]
id: ECTO:2000088
name: exposure to bisphosphonate agent therapy
def: "An exposure to bisphosphonate agent therapy." []
synonym: "bisphosphonate agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000954 ! has exposure stimulus bisphosphonate agent therapy
relationship: RO:0002309 MAXO:0000954 ! has exposure stimulus bisphosphonate agent therapy

[Term]
id: ECTO:2000089
name: exposure to calcium supplementation
def: "An exposure to calcium supplementation." []
synonym: "calcium supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001139 ! has exposure stimulus calcium supplementation
relationship: RO:0002309 MAXO:0001139 ! has exposure stimulus calcium supplementation

[Term]
id: ECTO:2000090
name: exposure to cholic acid supplementation
def: "An exposure to cholic acid supplementation." []
synonym: "cholic acid supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001255 ! has exposure stimulus cholic acid supplementation
relationship: RO:0002309 MAXO:0001255 ! has exposure stimulus cholic acid supplementation

[Term]
id: ECTO:2000091
name: exposure to cognitive behavior therapy
def: "An exposure to cognitive behavior therapy." []
synonym: "cognitive behavior therapy exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000883 ! has exposure stimulus cognitive behavior therapy
relationship: RO:0002309 MAXO:0000883 ! has exposure stimulus cognitive behavior therapy

[Term]
id: ECTO:2000092
name: exposure to cold water immersion therapy
def: "An exposure to cold water immersion therapy." []
synonym: "cold water immersion therapy exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000462 ! has exposure stimulus cold water immersion therapy
relationship: RO:0002309 MAXO:0000462 ! has exposure stimulus cold water immersion therapy

[Term]
id: ECTO:2000093
name: exposure to copper chelator agent therapy
def: "An exposure to copper chelator agent therapy." []
synonym: "copper chelator agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001224 ! has exposure stimulus copper chelator agent therapy
relationship: RO:0002309 MAXO:0001224 ! has exposure stimulus copper chelator agent therapy

[Term]
id: ECTO:2000094
name: exposure to GABA modulator therapy
def: "An exposure to GABA modulator therapy." []
synonym: "GABA modulator therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001322 ! has exposure stimulus GABA modulator therapy
relationship: RO:0002309 MAXO:0001322 ! has exposure stimulus GABA modulator therapy

[Term]
id: ECTO:2000095
name: exposure to hematopoietic stem cell transplantation
def: "An exposure to hematopoietic stem cell transplantation." []
synonym: "hematopoietic stem cell transplantation exposure" EXACT []
is_a: ECTO:2000056 ! exposure to transplant surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000747 ! has exposure stimulus hematopoietic stem cell transplantation
relationship: RO:0002309 MAXO:0000747 ! has exposure stimulus hematopoietic stem cell transplantation

[Term]
id: ECTO:2000096
name: exposure to interferon alpha therapy
def: "An exposure to interferon alpha therapy." []
synonym: "interferon alpha therapy exposure" EXACT []
is_a: ECTO:2000064 ! exposure to immune stimulant agent therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001486 ! has exposure stimulus interferon alpha therapy
relationship: RO:0002309 MAXO:0001486 ! has exposure stimulus interferon alpha therapy

[Term]
id: ECTO:2000097
name: exposure to iron supplementation
def: "An exposure to iron supplementation." []
synonym: "iron supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000108 ! has exposure stimulus iron supplementation
relationship: RO:0002309 MAXO:0000108 ! has exposure stimulus iron supplementation

[Term]
id: ECTO:2000098
name: exposure to isoleucine supplementation
def: "An exposure to isoleucine supplementation." []
synonym: "isoleucine supplementation exposure" EXACT []
is_a: ECTO:2000085 ! exposure to amino acid supplementation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001137 ! has exposure stimulus isoleucine supplementation
relationship: RO:0002309 MAXO:0001137 ! has exposure stimulus isoleucine supplementation

[Term]
id: ECTO:2000099
name: exposure to magnesium supplementation
def: "An exposure to magnesium supplementation." []
synonym: "magnesium supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001149 ! has exposure stimulus magnesium supplementation
relationship: RO:0002309 MAXO:0001149 ! has exposure stimulus magnesium supplementation

[Term]
id: ECTO:2000100
name: exposure to ornithine supplementation
def: "An exposure to ornithine supplementation." []
synonym: "ornithine supplementation exposure" EXACT []
is_a: ECTO:2000085 ! exposure to amino acid supplementation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010015 ! has exposure stimulus ornithine supplementation
relationship: RO:0002309 MAXO:0010015 ! has exposure stimulus ornithine supplementation

[Term]
id: ECTO:2000101
name: exposure to peritoneal dialysis
def: "An exposure to peritoneal dialysis." []
synonym: "peritoneal dialysis exposure" EXACT []
is_a: ECTO:2000104 ! exposure to renal replacement therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000603 ! has exposure stimulus peritoneal dialysis
relationship: RO:0002309 MAXO:0000603 ! has exposure stimulus peritoneal dialysis

[Term]
id: ECTO:2000102
name: exposure to platelet transfusion
def: "An exposure to platelet transfusion." []
synonym: "platelet transfusion exposure" EXACT []
is_a: ECTO:2000058 ! exposure to blood transfusion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001490 ! has exposure stimulus platelet transfusion
relationship: RO:0002309 MAXO:0001490 ! has exposure stimulus platelet transfusion

[Term]
id: ECTO:2000103
name: exposure to potassium supplementation
def: "An exposure to potassium supplementation." []
synonym: "potassium supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001123 ! has exposure stimulus potassium supplementation
relationship: RO:0002309 MAXO:0001123 ! has exposure stimulus potassium supplementation

[Term]
id: ECTO:2000104
name: exposure to renal replacement therapy
def: "An exposure to renal replacement therapy." []
synonym: "renal replacement therapy exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000600 ! has exposure stimulus renal replacement therapy
relationship: RO:0002309 MAXO:0000600 ! has exposure stimulus renal replacement therapy

[Term]
id: ECTO:2000105
name: exposure to serine supplementation
def: "An exposure to serine supplementation." []
synonym: "serine supplementation exposure" EXACT []
is_a: ECTO:2000085 ! exposure to amino acid supplementation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010021 ! has exposure stimulus serine supplementation
relationship: RO:0002309 MAXO:0010021 ! has exposure stimulus serine supplementation

[Term]
id: ECTO:2000106
name: exposure to soluble fiber supplementation
def: "An exposure to soluble fiber supplementation." []
synonym: "soluble fiber supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001147 ! has exposure stimulus soluble fiber supplementation
relationship: RO:0002309 MAXO:0001147 ! has exposure stimulus soluble fiber supplementation

[Term]
id: ECTO:2000107
name: exposure to sulfonylurea agent therapy
def: "An exposure to sulfonylurea agent therapy." []
synonym: "sulfonylurea agent therapy exposure" EXACT []
is_a: ECTO:2000035 ! exposure to glycemic agents
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000743 ! has exposure stimulus sulfonylurea agent therapy
relationship: RO:0002309 MAXO:0000743 ! has exposure stimulus sulfonylurea agent therapy

[Term]
id: ECTO:2000108
name: exposure to supplemental oxygen therapy with nasal cannula
def: "An exposure to supplemental oxygen therapy with nasal cannula." []
synonym: "supplemental oxygen therapy with nasal cannula exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000598 ! has exposure stimulus supplemental oxygen therapy with nasal cannula
relationship: RO:0002309 MAXO:0000598 ! has exposure stimulus supplemental oxygen therapy with nasal cannula

[Term]
id: ECTO:2000109
name: exposure to tumor necrosis factor inhibitor therapy
def: "An exposure to tumor necrosis factor inhibitor therapy." []
synonym: "tumor necrosis factor inhibitor therapy exposure" EXACT []
is_a: ECTO:2000119 ! exposure to immune suppressant agent therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001493 ! has exposure stimulus tumor necrosis factor inhibitor therapy
relationship: RO:0002309 MAXO:0001493 ! has exposure stimulus tumor necrosis factor inhibitor therapy

[Term]
id: ECTO:2000110
name: exposure to vitamin C supplementation
def: "An exposure to vitamin C supplementation." []
synonym: "vitamin C supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000109 ! has exposure stimulus vitamin C supplementation
relationship: RO:0002309 MAXO:0000109 ! has exposure stimulus vitamin C supplementation

[Term]
id: ECTO:2000111
name: exposure to weight loss pharmacotherapy
def: "An exposure to weight loss pharmacotherapy." []
synonym: "weight loss pharmacotherapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000909 ! has exposure stimulus weight loss pharmacotherapy
relationship: RO:0002309 MAXO:0000909 ! has exposure stimulus weight loss pharmacotherapy

[Term]
id: ECTO:2000112
name: exposure to photodynamic therapy
def: "An exposure to photodynamic therapy." []
synonym: "photodynamic therapy exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0020022 ! has exposure stimulus photodynamic therapy
relationship: RO:0002309 MAXO:0020022 ! has exposure stimulus photodynamic therapy

[Term]
id: ECTO:2000113
name: exposure to acupuncture therapy
def: "An exposure to acupuncture therapy." []
synonym: "acupuncture therapy exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000083 ! has exposure stimulus acupuncture therapy
relationship: RO:0002309 MAXO:0000083 ! has exposure stimulus acupuncture therapy

[Term]
id: ECTO:2000114
name: exposure to surgical procedure on cardiovascular system
def: "An exposure to surgical procedure on cardiovascular system." []
synonym: "surgical procedure on cardiovascular system exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0025001 ! has exposure stimulus surgical procedure on cardiovascular system
relationship: RO:0002309 MAXO:0025001 ! has exposure stimulus surgical procedure on cardiovascular system

[Term]
id: ECTO:2000115
name: exposure to cholecystectomy
def: "An exposure to cholecystectomy." []
synonym: "cholecystectomy exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001039 ! has exposure stimulus cholecystectomy
relationship: RO:0002309 MAXO:0001039 ! has exposure stimulus cholecystectomy

[Term]
id: ECTO:2000116
name: exposure to dietary fat or oil intake avoidance
def: "An exposure to dietary fat or oil intake avoidance." []
synonym: "dietary fat or oil intake avoidance exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010003 ! has exposure stimulus dietary fat or oil intake avoidance
relationship: RO:0002309 MAXO:0010003 ! has exposure stimulus dietary fat or oil intake avoidance

[Term]
id: ECTO:2000117
name: exposure to dietary sodium intake avoidance
def: "An exposure to dietary sodium intake avoidance." []
synonym: "dietary sodium intake avoidance exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0010096 ! has exposure stimulus dietary sodium intake avoidance
relationship: RO:0002309 MAXO:0010096 ! has exposure stimulus dietary sodium intake avoidance

[Term]
id: ECTO:2000118
name: exposure to fasting intervention
def: "An exposure to fasting intervention." []
synonym: "fasting intervention exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000098 ! has exposure stimulus fasting intervention
relationship: RO:0002309 MAXO:0000098 ! has exposure stimulus fasting intervention

[Term]
id: ECTO:2000119
name: exposure to immune suppressant agent therapy
def: "An exposure to immune suppressant agent therapy." []
synonym: "immune suppressant agent therapy exposure" EXACT []
is_a: ECTO:2000124 ! exposure to immunological agent therapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000297 ! has exposure stimulus immune suppressant agent therapy
relationship: RO:0002309 MAXO:0000297 ! has exposure stimulus immune suppressant agent therapy

[Term]
id: ECTO:2000120
name: exposure to gastrectomy
def: "An exposure to gastrectomy." []
synonym: "gastrectomy exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001053 ! has exposure stimulus gastrectomy
relationship: RO:0002309 MAXO:0001053 ! has exposure stimulus gastrectomy

[Term]
id: ECTO:2000121
name: exposure to low fat diet intake
def: "An exposure to low fat diet intake." []
synonym: "low fat diet intake exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000766 ! has exposure stimulus low fat diet intake
relationship: RO:0002309 MAXO:0000766 ! has exposure stimulus low fat diet intake

[Term]
id: ECTO:2000122
name: exposure to liver transplantation
def: "An exposure to liver transplantation." []
synonym: "liver transplantation exposure" EXACT []
is_a: ECTO:2000056 ! exposure to transplant surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001175 ! has exposure stimulus liver transplantation
relationship: RO:0002309 MAXO:0001175 ! has exposure stimulus liver transplantation

[Term]
id: ECTO:2000123
name: exposure to multivitamin supplementation
def: "An exposure to multivitamin supplementation." []
synonym: "multivitamin supplementation exposure" EXACT []
is_a: ECTO:2000068 ! exposure to dietary intervention
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000107 ! has exposure stimulus multivitamin supplementation
relationship: RO:0002309 MAXO:0000107 ! has exposure stimulus multivitamin supplementation

[Term]
id: ECTO:2000124
name: exposure to immunological agent therapy
def: "An exposure to immunological agent therapy." []
synonym: "immunological agent therapy exposure" EXACT []
is_a: ECTO:2000057 ! exposure to pharmacotherapy
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000295 ! has exposure stimulus immunological agent therapy
relationship: RO:0002309 MAXO:0000295 ! has exposure stimulus immunological agent therapy

[Term]
id: ECTO:2000125
name: exposure to preventative immunization
def: "An exposure to preventative immunization." []
synonym: "preventative immunization exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000118 ! has exposure stimulus preventative immunization
relationship: RO:0002309 MAXO:0000118 ! has exposure stimulus preventative immunization

[Term]
id: ECTO:2000126
name: exposure to oophorectomy
def: "An exposure to oophorectomy." []
synonym: "oophorectomy exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001067 ! has exposure stimulus oophorectomy
relationship: RO:0002309 MAXO:0001067 ! has exposure stimulus oophorectomy

[Term]
id: ECTO:2000127
name: exposure to splenectomy
def: "An exposure to splenectomy." []
synonym: "splenectomy exposure" EXACT []
is_a: ECTO:2000054 ! exposure to surgery
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001077 ! has exposure stimulus splenectomy
relationship: RO:0002309 MAXO:0001077 ! has exposure stimulus splenectomy

[Term]
id: ECTO:2000128
name: exposure to total parenteral nutrition intake
def: "An exposure to total parenteral nutrition intake." []
synonym: "total parenteral nutrition intake exposure" EXACT []
is_a: ECTO:2000000 ! exposure to medical action
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0000114 ! has exposure stimulus total parenteral nutrition intake
relationship: RO:0002309 MAXO:0000114 ! has exposure stimulus total parenteral nutrition intake

[Term]
id: ECTO:2000129
name: exposure to vaccination
def: "An exposure to vaccination." []
synonym: "vaccination exposure" EXACT []
is_a: ECTO:2000125 ! exposure to preventative immunization
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 MAXO:0001017 ! has exposure stimulus vaccination
relationship: RO:0002309 MAXO:0001017 ! has exposure stimulus vaccination

[Term]
id: ECTO:3000000
name: exposure to organism
def: "A history of exposure to root." []
synonym: "root exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1 ! has exposure stimulus root
relationship: RO:0002309 NCBITaxon:1 ! has exposure stimulus root

[Term]
id: ECTO:3000001
name: exposure to virus
def: "A history of exposure to Viruses." []
synonym: "Viruses exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10239 ! has exposure stimulus Viruses
relationship: RO:0002309 NCBITaxon:10239 ! has exposure stimulus Viruses

[Term]
id: ECTO:3000002
name: exposure to Enterovirus
def: "A history of exposure to Enterovirus." []
synonym: "Enterovirus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12059 ! has exposure stimulus Enterovirus
relationship: RO:0002309 NCBITaxon:12059 ! has exposure stimulus Enterovirus

[Term]
id: ECTO:3000003
name: exposure to Helicobacter pylori
def: "A history of exposure to Helicobacter pylori." []
synonym: "Helicobacter pylori exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:210 ! has exposure stimulus Helicobacter pylori
relationship: RO:0002309 NCBITaxon:210 ! has exposure stimulus Helicobacter pylori

[Term]
id: ECTO:3000004
name: exposure to Papillomaviridae
def: "A history of exposure to Papillomaviridae." []
synonym: "Papillomaviridae exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:151340 ! has exposure stimulus Papillomaviridae
relationship: RO:0002309 NCBITaxon:151340 ! has exposure stimulus Papillomaviridae

[Term]
id: ECTO:3000005
name: exposure to humans
def: "A history of exposure to Homo sapiens." []
synonym: "Homo sapiens exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:9606 ! has exposure stimulus Homo sapiens
relationship: RO:0002309 NCBITaxon:9606 ! has exposure stimulus Homo sapiens

[Term]
id: ECTO:3000006
name: exposure to Toxoplasma gondii
def: "A history of exposure to Toxoplasma gondii." []
synonym: "Toxoplasma gondii exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5811 ! has exposure stimulus Toxoplasma gondii
relationship: RO:0002309 NCBITaxon:5811 ! has exposure stimulus Toxoplasma gondii

[Term]
id: ECTO:3000007
name: exposure to Listeria
def: "A history of exposure to Listeria." []
synonym: "Listeria exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1637 ! has exposure stimulus Listeria
relationship: RO:0002309 NCBITaxon:1637 ! has exposure stimulus Listeria

[Term]
id: ECTO:3000008
name: exposure to Salmonella
def: "A history of exposure to Salmonella." []
synonym: "Salmonella exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:590 ! has exposure stimulus Salmonella
relationship: RO:0002309 NCBITaxon:590 ! has exposure stimulus Salmonella

[Term]
id: ECTO:3000009
name: exposure to Escherichia coli
def: "A history of exposure to Escherichia coli." []
synonym: "Escherichia coli exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:562 ! has exposure stimulus Escherichia coli
relationship: RO:0002309 NCBITaxon:562 ! has exposure stimulus Escherichia coli

[Term]
id: ECTO:3000010
name: exposure to human patient
def: "A history of exposure to patient." []
synonym: "patient exposure" EXACT []
is_a: ECTO:3000005 ! exposure to humans
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 OPMI:0000417 ! has exposure stimulus patient
relationship: RO:0002309 OPMI:0000417 ! has exposure stimulus patient

[Term]
id: ECTO:3000012
name: exposure to Acinetobacter baumannii
def: "A history of exposure to Acinetobacter baumannii." []
synonym: "Acinetobacter baumannii exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:470 ! has exposure stimulus Acinetobacter baumannii
relationship: RO:0002309 NCBITaxon:470 ! has exposure stimulus Acinetobacter baumannii

[Term]
id: ECTO:3000013
name: exposure to Acinetobacter lwoffii
def: "A history of exposure to Acinetobacter lwoffii." []
synonym: "Acinetobacter lwoffii exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:28090 ! has exposure stimulus Acinetobacter lwoffii
relationship: RO:0002309 NCBITaxon:28090 ! has exposure stimulus Acinetobacter lwoffii

[Term]
id: ECTO:3000014
name: exposure to Limosilactobacillus reuteri CF48-3A
def: "A history of exposure to Limosilactobacillus reuteri CF48-3A." []
synonym: "Limosilactobacillus reuteri CF48-3A exposure" EXACT []
is_a: ECTO:3000219 ! exposure to Limosilactobacillus reuteri
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:525341 ! has exposure stimulus Limosilactobacillus reuteri CF48-3A
relationship: RO:0002309 NCBITaxon:525341 ! has exposure stimulus Limosilactobacillus reuteri CF48-3A

[Term]
id: ECTO:3000015
name: exposure to African swine fever virus
def: "A history of exposure to African swine fever virus." []
synonym: "African swine fever virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10497 ! has exposure stimulus African swine fever virus
relationship: RO:0002309 NCBITaxon:10497 ! has exposure stimulus African swine fever virus

[Term]
id: ECTO:3000016
name: exposure to Akkermansia muciniphila
def: "A history of exposure to Akkermansia muciniphila." []
synonym: "Akkermansia muciniphila exposure" EXACT []
is_a: ECTO:3000195 ! exposure to Akkermansia
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:239935 ! has exposure stimulus Akkermansia muciniphila
relationship: RO:0002309 NCBITaxon:239935 ! has exposure stimulus Akkermansia muciniphila

[Term]
id: ECTO:3000017
name: exposure to Alistipes putredinis DSM 17216
def: "A history of exposure to Alistipes putredinis DSM 17216." []
synonym: "Alistipes putredinis DSM 17216 exposure" EXACT []
is_a: ECTO:3000018 ! exposure to Alistipes putredinis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:445970 ! has exposure stimulus Alistipes putredinis DSM 17216
relationship: RO:0002309 NCBITaxon:445970 ! has exposure stimulus Alistipes putredinis DSM 17216

[Term]
id: ECTO:3000018
name: exposure to Alistipes putredinis
def: "A history of exposure to Alistipes putredinis." []
synonym: "Alistipes putredinis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:28117 ! has exposure stimulus Alistipes putredinis
relationship: RO:0002309 NCBITaxon:28117 ! has exposure stimulus Alistipes putredinis

[Term]
id: ECTO:3000019
name: exposure to Amanita
def: "A history of exposure to Amanita." []
synonym: "Amanita exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:41955 ! has exposure stimulus Amanita
relationship: RO:0002309 NCBITaxon:41955 ! has exposure stimulus Amanita

[Term]
id: ECTO:3000020
name: exposure to Diaporthe
def: "A history of exposure to Diaporthe." []
synonym: "Diaporthe exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:36922 ! has exposure stimulus Diaporthe
relationship: RO:0002309 NCBITaxon:36922 ! has exposure stimulus Diaporthe

[Term]
id: ECTO:3000021
name: exposure to Sitobion avenae
def: "A history of exposure to Sitobion avenae." []
synonym: "Sitobion avenae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:44664 ! has exposure stimulus Sitobion avenae
relationship: RO:0002309 NCBITaxon:44664 ! has exposure stimulus Sitobion avenae

[Term]
id: ECTO:3000022
name: exposure to Aspergillus fumigatus var. fumigatus
def: "A history of exposure to Aspergillus fumigatus var. fumigatus." []
synonym: "Aspergillus fumigatus var. fumigatus exposure" EXACT []
is_a: ECTO:3000023 ! exposure to Aspergillus fumigatus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:41122 ! has exposure stimulus Aspergillus fumigatus var. fumigatus
relationship: RO:0002309 NCBITaxon:41122 ! has exposure stimulus Aspergillus fumigatus var. fumigatus

[Term]
id: ECTO:3000023
name: exposure to Aspergillus fumigatus
def: "A history of exposure to Aspergillus fumigatus." []
synonym: "Aspergillus fumigatus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:746128 ! has exposure stimulus Aspergillus fumigatus
relationship: RO:0002309 NCBITaxon:746128 ! has exposure stimulus Aspergillus fumigatus

[Term]
id: ECTO:3000024
name: exposure to Bacillus anthracis str. Sterne
def: "A history of exposure to Bacillus anthracis str. Sterne." []
synonym: "Bacillus anthracis str. Sterne exposure" EXACT []
is_a: ECTO:3000051 ! exposure to Bacillus <firmicutes>
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:260799 ! has exposure stimulus Bacillus anthracis str. Sterne
relationship: RO:0002309 NCBITaxon:260799 ! has exposure stimulus Bacillus anthracis str. Sterne

[Term]
id: ECTO:3000025
name: exposure to Bacillus sp. DU106(2010)
def: "A history of exposure to Bacillus sp. DU106(2010)." []
synonym: "Bacillus sp. DU106(2010) exposure" EXACT []
is_a: ECTO:3000051 ! exposure to Bacillus <firmicutes>
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:865093 ! has exposure stimulus Bacillus sp. DU106(2010)
relationship: RO:0002309 NCBITaxon:865093 ! has exposure stimulus Bacillus sp. DU106(2010)

[Term]
id: ECTO:3000026
name: exposure to Bacillus subtilis
def: "A history of exposure to Bacillus subtilis." []
synonym: "Bacillus subtilis exposure" EXACT []
is_a: ECTO:3000051 ! exposure to Bacillus <firmicutes>
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1423 ! has exposure stimulus Bacillus subtilis
relationship: RO:0002309 NCBITaxon:1423 ! has exposure stimulus Bacillus subtilis

[Term]
id: ECTO:3000027
name: exposure to Bacillus thuringiensis Bt18247
def: "A history of exposure to Bacillus thuringiensis Bt18247." []
synonym: "Bacillus thuringiensis Bt18247 exposure" EXACT []
is_a: ECTO:3000146 ! exposure to Bacillus thuringiensis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1423143 ! has exposure stimulus Bacillus thuringiensis Bt18247
relationship: RO:0002309 NCBITaxon:1423143 ! has exposure stimulus Bacillus thuringiensis Bt18247

[Term]
id: ECTO:3000028
name: exposure to Bacillus thuringiensis Bt407
def: "A history of exposure to Bacillus thuringiensis Bt407." []
synonym: "Bacillus thuringiensis Bt407 exposure" EXACT []
is_a: ECTO:3000146 ! exposure to Bacillus thuringiensis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:527021 ! has exposure stimulus Bacillus thuringiensis Bt407
relationship: RO:0002309 NCBITaxon:527021 ! has exposure stimulus Bacillus thuringiensis Bt407

[Term]
id: ECTO:3000029
name: exposure to Bacillus velezensis
def: "A history of exposure to Bacillus velezensis." []
synonym: "Bacillus velezensis exposure" EXACT []
is_a: ECTO:3000051 ! exposure to Bacillus <firmicutes>
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:492670 ! has exposure stimulus Bacillus velezensis
relationship: RO:0002309 NCBITaxon:492670 ! has exposure stimulus Bacillus velezensis

[Term]
id: ECTO:3000030
name: exposure to Staphylococcus aureus
def: "A history of exposure to Staphylococcus aureus." []
synonym: "Staphylococcus aureus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1280 ! has exposure stimulus Staphylococcus aureus
relationship: RO:0002309 NCBITaxon:1280 ! has exposure stimulus Staphylococcus aureus

[Term]
id: ECTO:3000031
name: exposure to Xanthomonas translucens
def: "A history of exposure to Xanthomonas translucens." []
synonym: "Xanthomonas translucens exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:343 ! has exposure stimulus Xanthomonas translucens
relationship: RO:0002309 NCBITaxon:343 ! has exposure stimulus Xanthomonas translucens

[Term]
id: ECTO:3000032
name: exposure to Pseudomonas syringae
def: "A history of exposure to Pseudomonas syringae." []
synonym: "Pseudomonas syringae exposure" EXACT []
is_a: ECTO:3000296 ! exposure to Pseudomonas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:317 ! has exposure stimulus Pseudomonas syringae
relationship: RO:0002309 NCBITaxon:317 ! has exposure stimulus Pseudomonas syringae

[Term]
id: ECTO:3000033
name: exposure to Bacteroides thetaiotaomicron
def: "A history of exposure to Bacteroides thetaiotaomicron." []
synonym: "Bacteroides thetaiotaomicron exposure" EXACT []
is_a: ECTO:3000085 ! exposure to Bacteroides
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:818 ! has exposure stimulus Bacteroides thetaiotaomicron
relationship: RO:0002309 NCBITaxon:818 ! has exposure stimulus Bacteroides thetaiotaomicron

[Term]
id: ECTO:3000034
name: exposure to Phocaeicola vulgatus CL09T03C04
def: "A history of exposure to Phocaeicola vulgatus CL09T03C04." []
synonym: "Phocaeicola vulgatus CL09T03C04 exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:997891 ! has exposure stimulus Phocaeicola vulgatus CL09T03C04
relationship: RO:0002309 NCBITaxon:997891 ! has exposure stimulus Phocaeicola vulgatus CL09T03C04

[Term]
id: ECTO:3000035
name: exposure to Barley yellow dwarf virus
def: "A history of exposure to Barley yellow dwarf virus." []
synonym: "Barley yellow dwarf virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12037 ! has exposure stimulus Barley yellow dwarf virus
relationship: RO:0002309 NCBITaxon:12037 ! has exposure stimulus Barley yellow dwarf virus

[Term]
id: ECTO:3000036
name: exposure to Beauveria bassiana
def: "A history of exposure to Beauveria bassiana." []
synonym: "Beauveria bassiana exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:176275 ! has exposure stimulus Beauveria bassiana
relationship: RO:0002309 NCBITaxon:176275 ! has exposure stimulus Beauveria bassiana

[Term]
id: ECTO:3000037
name: exposure to Bovine viral diarrhea virus 1
def: "A history of exposure to Bovine viral diarrhea virus 1." []
synonym: "Bovine viral diarrhea virus 1 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11099 ! has exposure stimulus Bovine viral diarrhea virus 1
relationship: RO:0002309 NCBITaxon:11099 ! has exposure stimulus Bovine viral diarrhea virus 1

[Term]
id: ECTO:3000038
name: exposure to Campylobacter jejuni subsp. jejuni
def: "A history of exposure to Campylobacter jejuni subsp. jejuni." []
synonym: "Campylobacter jejuni subsp. jejuni exposure" EXACT []
is_a: ECTO:3000255 ! exposure to Campylobacter jejuni
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:32022 ! has exposure stimulus Campylobacter jejuni subsp. jejuni
relationship: RO:0002309 NCBITaxon:32022 ! has exposure stimulus Campylobacter jejuni subsp. jejuni

[Term]
id: ECTO:3000039
name: exposure to Candida albicans
def: "A history of exposure to Candida albicans." []
synonym: "Candida albicans exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5476 ! has exposure stimulus Candida albicans
relationship: RO:0002309 NCBITaxon:5476 ! has exposure stimulus Candida albicans

[Term]
id: ECTO:3000040
name: exposure to Candidatus Liberibacter asiaticus
def: "A history of exposure to Candidatus Liberibacter asiaticus." []
synonym: "Candidatus Liberibacter asiaticus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:34021 ! has exposure stimulus Candidatus Liberibacter asiaticus
relationship: RO:0002309 NCBITaxon:34021 ! has exposure stimulus Candidatus Liberibacter asiaticus

[Term]
id: ECTO:3000041
name: exposure to Citrobacter rodentium
def: "A history of exposure to Citrobacter rodentium." []
synonym: "Citrobacter rodentium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:67825 ! has exposure stimulus Citrobacter rodentium
relationship: RO:0002309 NCBITaxon:67825 ! has exposure stimulus Citrobacter rodentium

[Term]
id: ECTO:3000042
name: exposure to Clostridioides difficile
def: "A history of exposure to Clostridioides difficile." []
synonym: "Clostridioides difficile exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1496 ! has exposure stimulus Clostridioides difficile
relationship: RO:0002309 NCBITaxon:1496 ! has exposure stimulus Clostridioides difficile

[Term]
id: ECTO:3000044
name: exposure to Bacteroides caccae
def: "A history of exposure to Bacteroides caccae." []
synonym: "Bacteroides caccae exposure" EXACT []
is_a: ECTO:3000085 ! exposure to Bacteroides
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:47678 ! has exposure stimulus Bacteroides caccae
relationship: RO:0002309 NCBITaxon:47678 ! has exposure stimulus Bacteroides caccae

[Term]
id: ECTO:3000045
name: exposure to Bacillus paramycoides
def: "A history of exposure to Bacillus paramycoides." []
synonym: "Bacillus paramycoides exposure" EXACT []
is_a: ECTO:3000051 ! exposure to Bacillus <firmicutes>
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2026194 ! has exposure stimulus Bacillus paramycoides
relationship: RO:0002309 NCBITaxon:2026194 ! has exposure stimulus Bacillus paramycoides

[Term]
id: ECTO:3000046
name: exposure to Mesorhizobium loti
def: "A history of exposure to Mesorhizobium loti." []
synonym: "Mesorhizobium loti exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:381 ! has exposure stimulus Mesorhizobium loti
relationship: RO:0002309 NCBITaxon:381 ! has exposure stimulus Mesorhizobium loti

[Term]
id: ECTO:3000047
name: exposure to Thalassiosira pseudonana
def: "A history of exposure to Thalassiosira pseudonana." []
synonym: "Thalassiosira pseudonana exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:35128 ! has exposure stimulus Thalassiosira pseudonana
relationship: RO:0002309 NCBITaxon:35128 ! has exposure stimulus Thalassiosira pseudonana

[Term]
id: ECTO:3000048
name: exposure to Bacillus siamensis
def: "A history of exposure to Bacillus siamensis." []
synonym: "Bacillus siamensis exposure" EXACT []
is_a: ECTO:3000051 ! exposure to Bacillus <firmicutes>
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:659243 ! has exposure stimulus Bacillus siamensis
relationship: RO:0002309 NCBITaxon:659243 ! has exposure stimulus Bacillus siamensis

[Term]
id: ECTO:3000049
name: exposure to Pseudomonas fluorescens
def: "A history of exposure to Pseudomonas fluorescens." []
synonym: "Pseudomonas fluorescens exposure" EXACT []
is_a: ECTO:3000296 ! exposure to Pseudomonas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:294 ! has exposure stimulus Pseudomonas fluorescens
relationship: RO:0002309 NCBITaxon:294 ! has exposure stimulus Pseudomonas fluorescens

[Term]
id: ECTO:3000050
name: exposure to Fusobacterium nucleatum
def: "A history of exposure to Fusobacterium nucleatum." []
synonym: "Fusobacterium nucleatum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:851 ! has exposure stimulus Fusobacterium nucleatum
relationship: RO:0002309 NCBITaxon:851 ! has exposure stimulus Fusobacterium nucleatum

[Term]
id: ECTO:3000051
name: exposure to Bacillus <firmicutes>
def: "A history of exposure to Bacillus <firmicutes>." []
synonym: "Bacillus <firmicutes> exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1386 ! has exposure stimulus Bacillus <firmicutes>
relationship: RO:0002309 NCBITaxon:1386 ! has exposure stimulus Bacillus <firmicutes>

[Term]
id: ECTO:3000052
name: exposure to Companilactobacillus alimentarius
def: "A history of exposure to Companilactobacillus alimentarius." []
synonym: "Companilactobacillus alimentarius exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1602 ! has exposure stimulus Companilactobacillus alimentarius
relationship: RO:0002309 NCBITaxon:1602 ! has exposure stimulus Companilactobacillus alimentarius

[Term]
id: ECTO:3000053
name: exposure to Coxsackievirus A6
def: "A history of exposure to Coxsackievirus A6." []
synonym: "Coxsackievirus A6 exposure" EXACT []
is_a: ECTO:3000002 ! exposure to Enterovirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:86107 ! has exposure stimulus Coxsackievirus A6
relationship: RO:0002309 NCBITaxon:86107 ! has exposure stimulus Coxsackievirus A6

[Term]
id: ECTO:3000054
name: exposure to Crithidia bombi
def: "A history of exposure to Crithidia bombi." []
synonym: "Crithidia bombi exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:288676 ! has exposure stimulus Crithidia bombi
relationship: RO:0002309 NCBITaxon:288676 ! has exposure stimulus Crithidia bombi

[Term]
id: ECTO:3000055
name: exposure to Cryptococcus neoformans species complex
def: "A history of exposure to Cryptococcus neoformans species complex." []
synonym: "Cryptococcus neoformans species complex exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1897064 ! has exposure stimulus Cryptococcus neoformans species complex
relationship: RO:0002309 NCBITaxon:1897064 ! has exposure stimulus Cryptococcus neoformans species complex

[Term]
id: ECTO:3000056
name: exposure to Cucumber mosaic virus
def: "A history of exposure to Cucumber mosaic virus." []
synonym: "Cucumber mosaic virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12305 ! has exposure stimulus Cucumber mosaic virus
relationship: RO:0002309 NCBITaxon:12305 ! has exposure stimulus Cucumber mosaic virus

[Term]
id: ECTO:3000057
name: exposure to Lactiplantibacillus plantarum
def: "A history of exposure to Lactiplantibacillus plantarum." []
synonym: "Lactiplantibacillus plantarum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1590 ! has exposure stimulus Lactiplantibacillus plantarum
relationship: RO:0002309 NCBITaxon:1590 ! has exposure stimulus Lactiplantibacillus plantarum

[Term]
id: ECTO:3000059
name: exposure to Diplodia sapinea
def: "A history of exposure to Diplodia sapinea." []
synonym: "Diplodia sapinea exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:66738 ! has exposure stimulus Diplodia sapinea
relationship: RO:0002309 NCBITaxon:66738 ! has exposure stimulus Diplodia sapinea

[Term]
id: ECTO:3000060
name: exposure to Diplodia sapinea CMW 190
def: "A history of exposure to Diplodia sapinea CMW 190." []
synonym: "Diplodia sapinea CMW 190 exposure" EXACT []
is_a: ECTO:3000059 ! exposure to Diplodia sapinea
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1400760 ! has exposure stimulus Diplodia sapinea CMW 190
relationship: RO:0002309 NCBITaxon:1400760 ! has exposure stimulus Diplodia sapinea CMW 190

[Term]
id: ECTO:3000061
name: exposure to Dubosiella
def: "A history of exposure to Dubosiella." []
synonym: "Dubosiella exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1937008 ! has exposure stimulus Dubosiella
relationship: RO:0002309 NCBITaxon:1937008 ! has exposure stimulus Dubosiella

[Term]
id: ECTO:3000062
name: exposure to Paxillus involutus f. eburneus
def: "A history of exposure to Paxillus involutus f. eburneus." []
synonym: "Paxillus involutus f. eburneus exposure" EXACT []
is_a: ECTO:3000265 ! exposure to Paxillus involutus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1124488 ! has exposure stimulus Paxillus involutus f. eburneus
relationship: RO:0002309 NCBITaxon:1124488 ! has exposure stimulus Paxillus involutus f. eburneus

[Term]
id: ECTO:3000063
name: exposure to Veillonella sp. oral taxon 780 str. F0422
def: "A history of exposure to Veillonella sp. oral taxon 780 str. F0422." []
synonym: "Veillonella sp. oral taxon 780 str. F0422 exposure" EXACT []
is_a: ECTO:3000266 ! exposure to Veillonella
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:944564 ! has exposure stimulus Veillonella sp. oral taxon 780 str. F0422
relationship: RO:0002309 NCBITaxon:944564 ! has exposure stimulus Veillonella sp. oral taxon 780 str. F0422

[Term]
id: ECTO:3000064
name: exposure to Agrilus planipennis
def: "A history of exposure to Agrilus planipennis." []
synonym: "Agrilus planipennis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:224129 ! has exposure stimulus Agrilus planipennis
relationship: RO:0002309 NCBITaxon:224129 ! has exposure stimulus Agrilus planipennis

[Term]
id: ECTO:3000065
name: exposure to Enterobacter hormaechei
def: "A history of exposure to Enterobacter hormaechei." []
synonym: "Enterobacter hormaechei exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:158836 ! has exposure stimulus Enterobacter hormaechei
relationship: RO:0002309 NCBITaxon:158836 ! has exposure stimulus Enterobacter hormaechei

[Term]
id: ECTO:3000066
name: exposure to Enterococcus faecalis
def: "A history of exposure to Enterococcus faecalis." []
synonym: "Enterococcus faecalis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1351 ! has exposure stimulus Enterococcus faecalis
relationship: RO:0002309 NCBITaxon:1351 ! has exposure stimulus Enterococcus faecalis

[Term]
id: ECTO:3000067
name: exposure to Bacteroides fragilis NCTC 9343
def: "A history of exposure to Bacteroides fragilis NCTC 9343." []
synonym: "Bacteroides fragilis NCTC 9343 exposure" EXACT []
is_a: ECTO:3000068 ! exposure to Bacteroides fragilis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:272559 ! has exposure stimulus Bacteroides fragilis NCTC 9343
relationship: RO:0002309 NCBITaxon:272559 ! has exposure stimulus Bacteroides fragilis NCTC 9343

[Term]
id: ECTO:3000068
name: exposure to Bacteroides fragilis
def: "A history of exposure to Bacteroides fragilis." []
synonym: "Bacteroides fragilis exposure" EXACT []
is_a: ECTO:3000085 ! exposure to Bacteroides
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:817 ! has exposure stimulus Bacteroides fragilis
relationship: RO:0002309 NCBITaxon:817 ! has exposure stimulus Bacteroides fragilis

[Term]
id: ECTO:3000069
name: exposure to Epichloe gansuensis var. inebrians E818
def: "A history of exposure to Epichloe gansuensis var. inebrians E818." []
synonym: "Epichloe gansuensis var. inebrians E818 exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1227659 ! has exposure stimulus Epichloe gansuensis var. inebrians E818
relationship: RO:0002309 NCBITaxon:1227659 ! has exposure stimulus Epichloe gansuensis var. inebrians E818

[Term]
id: ECTO:3000070
name: exposure to Borrelia
def: "A history of exposure to Borrelia." []
synonym: "Borrelia exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:138 ! has exposure stimulus Borrelia
relationship: RO:0002309 NCBITaxon:138 ! has exposure stimulus Borrelia

[Term]
id: ECTO:3000071
name: exposure to Symbiodinium sp. subtype D1a ex Pteraeolidia ianthina
def: "A history of exposure to Symbiodinium sp. subtype D1a ex Pteraeolidia ianthina." []
synonym: "Symbiodinium sp. subtype D1a ex Pteraeolidia ianthina exposure" EXACT []
is_a: ECTO:3000181 ! exposure to Symbiodinium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1509513 ! has exposure stimulus Symbiodinium sp. subtype D1a ex Pteraeolidia ianthina
relationship: RO:0002309 NCBITaxon:1509513 ! has exposure stimulus Symbiodinium sp. subtype D1a ex Pteraeolidia ianthina

[Term]
id: ECTO:3000072
name: exposure to Faecalibaculum rodentium
def: "A history of exposure to Faecalibaculum rodentium." []
synonym: "Faecalibaculum rodentium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1702221 ! has exposure stimulus Faecalibaculum rodentium
relationship: RO:0002309 NCBITaxon:1702221 ! has exposure stimulus Faecalibaculum rodentium

[Term]
id: ECTO:3000073
name: exposure to Nicotiana attenuata
def: "A history of exposure to Nicotiana attenuata." []
synonym: "Nicotiana attenuata exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:49451 ! has exposure stimulus Nicotiana attenuata
relationship: RO:0002309 NCBITaxon:49451 ! has exposure stimulus Nicotiana attenuata

[Term]
id: ECTO:3000074
name: exposure to Flavivirus
def: "A history of exposure to Orthoflavivirus." []
synonym: "Orthoflavivirus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:3044782 ! has exposure stimulus Orthoflavivirus
relationship: RO:0002309 NCBITaxon:3044782 ! has exposure stimulus Orthoflavivirus

[Term]
id: ECTO:3000075
name: exposure to Yellow fever virus
def: "A history of exposure to Yellow fever virus." []
synonym: "Yellow fever virus exposure" EXACT []
is_a: ECTO:3000074 ! exposure to Flavivirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11089 ! has exposure stimulus Yellow fever virus
relationship: RO:0002309 NCBITaxon:11089 ! has exposure stimulus Yellow fever virus

[Term]
id: ECTO:3000076
name: exposure to Zika virus
def: "A history of exposure to Zika virus." []
synonym: "Zika virus exposure" EXACT []
is_a: ECTO:3000074 ! exposure to Flavivirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:64320 ! has exposure stimulus Zika virus
relationship: RO:0002309 NCBITaxon:64320 ! has exposure stimulus Zika virus

[Term]
id: ECTO:3000077
name: exposure to Ceratocystis manginecans
def: "A history of exposure to Ceratocystis manginecans." []
synonym: "Ceratocystis manginecans exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:929235 ! has exposure stimulus Ceratocystis manginecans
relationship: RO:0002309 NCBITaxon:929235 ! has exposure stimulus Ceratocystis manginecans

[Term]
id: ECTO:3000078
name: exposure to Fusarium culmorum
def: "A history of exposure to Fusarium culmorum." []
synonym: "Fusarium culmorum exposure" EXACT []
is_a: ECTO:3000082 ! exposure to Fusarium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5516 ! has exposure stimulus Fusarium culmorum
relationship: RO:0002309 NCBITaxon:5516 ! has exposure stimulus Fusarium culmorum

[Term]
id: ECTO:3000079
name: exposure to Fusarium graminearum
def: "A history of exposure to Fusarium graminearum." []
synonym: "Fusarium graminearum exposure" EXACT []
is_a: ECTO:3000082 ! exposure to Fusarium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5518 ! has exposure stimulus Fusarium graminearum
relationship: RO:0002309 NCBITaxon:5518 ! has exposure stimulus Fusarium graminearum

[Term]
id: ECTO:3000080
name: exposure to Fusarium keratoplasticum
def: "A history of exposure to Fusarium keratoplasticum." []
synonym: "Fusarium keratoplasticum exposure" EXACT []
is_a: ECTO:3000082 ! exposure to Fusarium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1328300 ! has exposure stimulus Fusarium keratoplasticum
relationship: RO:0002309 NCBITaxon:1328300 ! has exposure stimulus Fusarium keratoplasticum

[Term]
id: ECTO:3000081
name: exposure to Fusarium oxysporum
def: "A history of exposure to Fusarium oxysporum." []
synonym: "Fusarium oxysporum exposure" EXACT []
is_a: ECTO:3000082 ! exposure to Fusarium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5507 ! has exposure stimulus Fusarium oxysporum
relationship: RO:0002309 NCBITaxon:5507 ! has exposure stimulus Fusarium oxysporum

[Term]
id: ECTO:3000082
name: exposure to Fusarium
def: "A history of exposure to Fusarium." []
synonym: "Fusarium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5506 ! has exposure stimulus Fusarium
relationship: RO:0002309 NCBITaxon:5506 ! has exposure stimulus Fusarium

[Term]
id: ECTO:3000083
name: exposure to Fusarium pseudograminearum
def: "A history of exposure to Fusarium pseudograminearum." []
synonym: "Fusarium pseudograminearum exposure" EXACT []
is_a: ECTO:3000082 ! exposure to Fusarium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:101028 ! has exposure stimulus Fusarium pseudograminearum
relationship: RO:0002309 NCBITaxon:101028 ! has exposure stimulus Fusarium pseudograminearum

[Term]
id: ECTO:3000084
name: exposure to Gardnerella vaginalis
def: "A history of exposure to Gardnerella vaginalis." []
synonym: "Gardnerella vaginalis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2702 ! has exposure stimulus Gardnerella vaginalis
relationship: RO:0002309 NCBITaxon:2702 ! has exposure stimulus Gardnerella vaginalis

[Term]
id: ECTO:3000085
name: exposure to Bacteroides
def: "A history of exposure to Bacteroides." []
synonym: "Bacteroides exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:816 ! has exposure stimulus Bacteroides
relationship: RO:0002309 NCBITaxon:816 ! has exposure stimulus Bacteroides

[Term]
id: ECTO:3000086
name: exposure to Rhizopus microsporus var. rhizopodiformis
def: "A history of exposure to Rhizopus microsporus var. rhizopodiformis." []
synonym: "Rhizopus microsporus var. rhizopodiformis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:90259 ! has exposure stimulus Rhizopus microsporus var. rhizopodiformis
relationship: RO:0002309 NCBITaxon:90259 ! has exposure stimulus Rhizopus microsporus var. rhizopodiformis

[Term]
id: ECTO:3000087
name: exposure to Grass carp reovirus
def: "A history of exposure to Grass carp reovirus." []
synonym: "Grass carp reovirus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:128987 ! has exposure stimulus Grass carp reovirus
relationship: RO:0002309 NCBITaxon:128987 ! has exposure stimulus Grass carp reovirus

[Term]
id: ECTO:3000088
name: exposure to Giardiavirus
def: "A history of exposure to Giardiavirus." []
synonym: "Giardiavirus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11011 ! has exposure stimulus Giardiavirus
relationship: RO:0002309 NCBITaxon:11011 ! has exposure stimulus Giardiavirus

[Term]
id: ECTO:3000089
name: exposure to Calanus
def: "A history of exposure to Calanus." []
synonym: "Calanus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6836 ! has exposure stimulus Calanus
relationship: RO:0002309 NCBITaxon:6836 ! has exposure stimulus Calanus

[Term]
id: ECTO:3000090
name: exposure to Centropages
def: "A history of exposure to Centropages." []
synonym: "Centropages exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:136182 ! has exposure stimulus Centropages
relationship: RO:0002309 NCBITaxon:136182 ! has exposure stimulus Centropages

[Term]
id: ECTO:3000091
name: exposure to Myzus persicae
def: "A history of exposure to Myzus persicae." []
synonym: "Myzus persicae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:13164 ! has exposure stimulus Myzus persicae
relationship: RO:0002309 NCBITaxon:13164 ! has exposure stimulus Myzus persicae

[Term]
id: ECTO:3000092
name: exposure to Lactobacillus
def: "A history of exposure to Lactobacillus." []
synonym: "Lactobacillus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1578 ! has exposure stimulus Lactobacillus
relationship: RO:0002309 NCBITaxon:1578 ! has exposure stimulus Lactobacillus

[Term]
id: ECTO:3000093
name: exposure to Heligmosomoides polygyrus
def: "A history of exposure to Heligmosomoides polygyrus." []
synonym: "Heligmosomoides polygyrus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6339 ! has exposure stimulus Heligmosomoides polygyrus
relationship: RO:0002309 NCBITaxon:6339 ! has exposure stimulus Heligmosomoides polygyrus

[Term]
id: ECTO:3000094
name: exposure to Hepatitis B virus
def: "A history of exposure to Hepatitis B virus." []
synonym: "Hepatitis B virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10407 ! has exposure stimulus Hepatitis B virus
relationship: RO:0002309 NCBITaxon:10407 ! has exposure stimulus Hepatitis B virus

[Term]
id: ECTO:3000095
name: exposure to Hepatitis C virus HCV-476
def: "A history of exposure to Hepatitis C virus HCV-476." []
synonym: "Hepatitis C virus HCV-476 exposure" EXACT []
is_a: ECTO:3000284 ! exposure to Hepacivirus hominis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:31643 ! has exposure stimulus Hepatitis C virus HCV-476
relationship: RO:0002309 NCBITaxon:31643 ! has exposure stimulus Hepatitis C virus HCV-476

[Term]
id: ECTO:3000096
name: exposure to Hepatitis E virus
def: "A history of exposure to Hepatitis E virus." []
synonym: "Hepatitis E virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:291484 ! has exposure stimulus Hepatitis E virus
relationship: RO:0002309 NCBITaxon:291484 ! has exposure stimulus Hepatitis E virus

[Term]
id: ECTO:3000097
name: exposure to Human alphaherpesvirus 1
def: "A history of exposure to Human alphaherpesvirus 1." []
synonym: "Human alphaherpesvirus 1 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10298 ! has exposure stimulus Human alphaherpesvirus 1
relationship: RO:0002309 NCBITaxon:10298 ! has exposure stimulus Human alphaherpesvirus 1

[Term]
id: ECTO:3000098
name: exposure to Human immunodeficiency virus type 1 (HXB3 ISOLATE)
def: "A history of exposure to Human immunodeficiency virus type 1 (HXB3 ISOLATE)." []
synonym: "Human immunodeficiency virus type 1 (HXB3 ISOLATE) exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11707 ! has exposure stimulus Human immunodeficiency virus type 1 (HXB3 ISOLATE)
relationship: RO:0002309 NCBITaxon:11707 ! has exposure stimulus Human immunodeficiency virus type 1 (HXB3 ISOLATE)

[Term]
id: ECTO:3000099
name: exposure to Human betaherpesvirus 5
def: "A history of exposure to Human betaherpesvirus 5." []
synonym: "Human betaherpesvirus 5 exposure" EXACT []
is_a: ECTO:3000205 ! exposure to Cytomegalovirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10359 ! has exposure stimulus Human betaherpesvirus 5
relationship: RO:0002309 NCBITaxon:10359 ! has exposure stimulus Human betaherpesvirus 5

[Term]
id: ECTO:3000100
name: exposure to Human betaherpesvirus 6
def: "A history of exposure to Human betaherpesvirus 6." []
synonym: "Human betaherpesvirus 6 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10368 ! has exposure stimulus Human betaherpesvirus 6
relationship: RO:0002309 NCBITaxon:10368 ! has exposure stimulus Human betaherpesvirus 6

[Term]
id: ECTO:3000101
name: exposure to Ichthyophthirius multifiliis
def: "A history of exposure to Ichthyophthirius multifiliis." []
synonym: "Ichthyophthirius multifiliis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5932 ! has exposure stimulus Ichthyophthirius multifiliis
relationship: RO:0002309 NCBITaxon:5932 ! has exposure stimulus Ichthyophthirius multifiliis

[Term]
id: ECTO:3000102
name: exposure to Trypanosoma brucei
def: "A history of exposure to Trypanosoma brucei." []
synonym: "Trypanosoma brucei exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5691 ! has exposure stimulus Trypanosoma brucei
relationship: RO:0002309 NCBITaxon:5691 ! has exposure stimulus Trypanosoma brucei

[Term]
id: ECTO:3000103
name: exposure to Newcastle disease virus (strain H)
def: "A history of exposure to Newcastle disease virus (strain H)." []
synonym: "Newcastle disease virus (strain H) exposure" EXACT []
is_a: ECTO:3000303 ! exposure to avian paramyxovirus 1
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:71570 ! has exposure stimulus Newcastle disease virus (strain H)
relationship: RO:0002309 NCBITaxon:71570 ! has exposure stimulus Newcastle disease virus (strain H)

[Term]
id: ECTO:3000104
name: exposure to Infectious bronchitis virus
def: "A history of exposure to Infectious bronchitis virus." []
synonym: "Infectious bronchitis virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11120 ! has exposure stimulus Infectious bronchitis virus
relationship: RO:0002309 NCBITaxon:11120 ! has exposure stimulus Infectious bronchitis virus

[Term]
id: ECTO:3000107
name: exposure to Influenza A virus
def: "A history of exposure to Influenza A virus." []
synonym: "Influenza A virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11320 ! has exposure stimulus Influenza A virus
relationship: RO:0002309 NCBITaxon:11320 ! has exposure stimulus Influenza A virus

[Term]
id: ECTO:3000110
name: exposure to Bacillus thuringiensis serovar kurstaki str. HD-1
def: "A history of exposure to Bacillus thuringiensis serovar kurstaki str. HD-1." []
synonym: "Bacillus thuringiensis serovar kurstaki str. HD-1 exposure" EXACT []
is_a: ECTO:3000146 ! exposure to Bacillus thuringiensis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1261129 ! has exposure stimulus Bacillus thuringiensis serovar kurstaki str. HD-1
relationship: RO:0002309 NCBITaxon:1261129 ! has exposure stimulus Bacillus thuringiensis serovar kurstaki str. HD-1

[Term]
id: ECTO:3000111
name: exposure to Penicillium roqueforti
def: "A history of exposure to Penicillium roqueforti." []
synonym: "Penicillium roqueforti exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5082 ! has exposure stimulus Penicillium roqueforti
relationship: RO:0002309 NCBITaxon:5082 ! has exposure stimulus Penicillium roqueforti

[Term]
id: ECTO:3000113
name: exposure to ammonia-oxidizing bacterium enrichment culture isolate DGGE gel band AOB4
def: "A history of exposure to ammonia-oxidizing bacterium enrichment culture isolate DGGE gel band AOB4." []
synonym: "ammonia-oxidizing bacterium enrichment culture isolate DGGE gel band AOB4 exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1385647 ! has exposure stimulus ammonia-oxidizing bacterium enrichment culture isolate DGGE gel band AOB4
relationship: RO:0002309 NCBITaxon:1385647 ! has exposure stimulus ammonia-oxidizing bacterium enrichment culture isolate DGGE gel band AOB4

[Term]
id: ECTO:3000114
name: exposure to Plasmodium knowlesi
def: "A history of exposure to Plasmodium knowlesi." []
synonym: "Plasmodium knowlesi exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5850 ! has exposure stimulus Plasmodium knowlesi
relationship: RO:0002309 NCBITaxon:5850 ! has exposure stimulus Plasmodium knowlesi

[Term]
id: ECTO:3000115
name: exposure to Bacillus thuringiensis IBL 4222
def: "A history of exposure to Bacillus thuringiensis IBL 4222." []
synonym: "Bacillus thuringiensis IBL 4222 exposure" EXACT []
is_a: ECTO:3000146 ! exposure to Bacillus thuringiensis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:527020 ! has exposure stimulus Bacillus thuringiensis IBL 4222
relationship: RO:0002309 NCBITaxon:527020 ! has exposure stimulus Bacillus thuringiensis IBL 4222

[Term]
id: ECTO:3000116
name: exposure to Human gammaherpesvirus 8
def: "A history of exposure to Human gammaherpesvirus 8." []
synonym: "Human gammaherpesvirus 8 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:37296 ! has exposure stimulus Human gammaherpesvirus 8
relationship: RO:0002309 NCBITaxon:37296 ! has exposure stimulus Human gammaherpesvirus 8

[Term]
id: ECTO:3000117
name: exposure to Klebsiella pneumoniae
def: "A history of exposure to Klebsiella pneumoniae." []
synonym: "Klebsiella pneumoniae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:573 ! has exposure stimulus Klebsiella pneumoniae
relationship: RO:0002309 NCBITaxon:573 ! has exposure stimulus Klebsiella pneumoniae

[Term]
id: ECTO:3000118
name: exposure to Lachnospiraceae bacterium
def: "A history of exposure to Lachnospiraceae bacterium." []
synonym: "Lachnospiraceae bacterium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1898203 ! has exposure stimulus Lachnospiraceae bacterium
relationship: RO:0002309 NCBITaxon:1898203 ! has exposure stimulus Lachnospiraceae bacterium

[Term]
id: ECTO:3000119
name: exposure to Lacticaseibacillus paracasei
def: "A history of exposure to Lacticaseibacillus paracasei." []
synonym: "Lacticaseibacillus paracasei exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1597 ! has exposure stimulus Lacticaseibacillus paracasei
relationship: RO:0002309 NCBITaxon:1597 ! has exposure stimulus Lacticaseibacillus paracasei

[Term]
id: ECTO:3000120
name: exposure to Lactobacillus crispatus
def: "A history of exposure to Lactobacillus crispatus." []
synonym: "Lactobacillus crispatus exposure" EXACT []
is_a: ECTO:3000092 ! exposure to Lactobacillus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:47770 ! has exposure stimulus Lactobacillus crispatus
relationship: RO:0002309 NCBITaxon:47770 ! has exposure stimulus Lactobacillus crispatus

[Term]
id: ECTO:3000121
name: exposure to Lactobacillus johnsonii
def: "A history of exposure to Lactobacillus johnsonii." []
synonym: "Lactobacillus johnsonii exposure" EXACT []
is_a: ECTO:3000092 ! exposure to Lactobacillus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:33959 ! has exposure stimulus Lactobacillus johnsonii
relationship: RO:0002309 NCBITaxon:33959 ! has exposure stimulus Lactobacillus johnsonii

[Term]
id: ECTO:3000122
name: exposure to Lacticaseibacillus rhamnosus
def: "A history of exposure to Lacticaseibacillus rhamnosus." []
synonym: "Lacticaseibacillus rhamnosus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:47715 ! has exposure stimulus Lacticaseibacillus rhamnosus
relationship: RO:0002309 NCBITaxon:47715 ! has exposure stimulus Lacticaseibacillus rhamnosus

[Term]
id: ECTO:3000123
name: exposure to Leuconostoc lactis
def: "A history of exposure to Leuconostoc lactis." []
synonym: "Leuconostoc lactis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1246 ! has exposure stimulus Leuconostoc lactis
relationship: RO:0002309 NCBITaxon:1246 ! has exposure stimulus Leuconostoc lactis

[Term]
id: ECTO:3000124
name: exposure to Limosilactobacillus fermentum
def: "A history of exposure to Limosilactobacillus fermentum." []
synonym: "Limosilactobacillus fermentum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1613 ! has exposure stimulus Limosilactobacillus fermentum
relationship: RO:0002309 NCBITaxon:1613 ! has exposure stimulus Limosilactobacillus fermentum

[Term]
id: ECTO:3000125
name: exposure to Listeria monocytogenes
def: "A history of exposure to Listeria monocytogenes." []
synonym: "Listeria monocytogenes exposure" EXACT []
is_a: ECTO:3000007 ! exposure to Listeria
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1639 ! has exposure stimulus Listeria monocytogenes
relationship: RO:0002309 NCBITaxon:1639 ! has exposure stimulus Listeria monocytogenes

[Term]
id: ECTO:3000126
name: exposure to Pyricularia oryzae
def: "A history of exposure to Pyricularia oryzae." []
synonym: "Pyricularia oryzae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:318829 ! has exposure stimulus Pyricularia oryzae
relationship: RO:0002309 NCBITaxon:318829 ! has exposure stimulus Pyricularia oryzae

[Term]
id: ECTO:3000127
name: exposure to Manduca sexta
def: "A history of exposure to Manduca sexta." []
synonym: "Manduca sexta exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:7130 ! has exposure stimulus Manduca sexta
relationship: RO:0002309 NCBITaxon:7130 ! has exposure stimulus Manduca sexta

[Term]
id: ECTO:3000128
name: exposure to Mayaro virus
def: "A history of exposure to Mayaro virus." []
synonym: "Mayaro virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:59301 ! has exposure stimulus Mayaro virus
relationship: RO:0002309 NCBITaxon:59301 ! has exposure stimulus Mayaro virus

[Term]
id: ECTO:3000129
name: exposure to Meloidogyne incognita
def: "A history of exposure to Meloidogyne incognita." []
synonym: "Meloidogyne incognita exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6306 ! has exposure stimulus Meloidogyne incognita
relationship: RO:0002309 NCBITaxon:6306 ! has exposure stimulus Meloidogyne incognita

[Term]
id: ECTO:3000130
name: exposure to Middle East respiratory syndrome-related coronavirus
def: "A history of exposure to Middle East respiratory syndrome-related coronavirus." []
synonym: "Middle East respiratory syndrome-related coronavirus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1335626 ! has exposure stimulus Middle East respiratory syndrome-related coronavirus
relationship: RO:0002309 NCBITaxon:1335626 ! has exposure stimulus Middle East respiratory syndrome-related coronavirus

[Term]
id: ECTO:3000131
name: exposure to Bacteroides thetaiotaomicron VPI-5482
def: "A history of exposure to Bacteroides thetaiotaomicron VPI-5482." []
synonym: "Bacteroides thetaiotaomicron VPI-5482 exposure" EXACT []
is_a: ECTO:3000033 ! exposure to Bacteroides thetaiotaomicron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:226186 ! has exposure stimulus Bacteroides thetaiotaomicron VPI-5482
relationship: RO:0002309 NCBITaxon:226186 ! has exposure stimulus Bacteroides thetaiotaomicron VPI-5482

[Term]
id: ECTO:3000132
name: exposure to Mycobacterium avium subsp. paratuberculosis
def: "A history of exposure to Mycobacterium avium subsp. paratuberculosis." []
synonym: "Mycobacterium avium subsp. paratuberculosis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1770 ! has exposure stimulus Mycobacterium avium subsp. paratuberculosis
relationship: RO:0002309 NCBITaxon:1770 ! has exposure stimulus Mycobacterium avium subsp. paratuberculosis

[Term]
id: ECTO:3000133
name: exposure to Mycobacterium tuberculosis subsp. tuberculosis
def: "A history of exposure to Mycobacterium tuberculosis subsp. tuberculosis." []
synonym: "Mycobacterium tuberculosis subsp. tuberculosis exposure" EXACT []
is_a: ECTO:3000134 ! exposure to Mycobacterium tuberculosis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:182785 ! has exposure stimulus Mycobacterium tuberculosis subsp. tuberculosis
relationship: RO:0002309 NCBITaxon:182785 ! has exposure stimulus Mycobacterium tuberculosis subsp. tuberculosis

[Term]
id: ECTO:3000134
name: exposure to Mycobacterium tuberculosis
def: "A history of exposure to Mycobacterium tuberculosis." []
synonym: "Mycobacterium tuberculosis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1773 ! has exposure stimulus Mycobacterium tuberculosis
relationship: RO:0002309 NCBITaxon:1773 ! has exposure stimulus Mycobacterium tuberculosis

[Term]
id: ECTO:3000135
name: exposure to Nippostrongylus brasiliensis
def: "A history of exposure to Nippostrongylus brasiliensis." []
synonym: "Nippostrongylus brasiliensis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:27835 ! has exposure stimulus Nippostrongylus brasiliensis
relationship: RO:0002309 NCBITaxon:27835 ! has exposure stimulus Nippostrongylus brasiliensis

[Term]
id: ECTO:3000136
name: exposure to Ophiocordyceps sinensis
def: "A history of exposure to Ophiocordyceps sinensis." []
synonym: "Ophiocordyceps sinensis exposure" EXACT []
is_a: ECTO:3000222 ! exposure to Ophiocordyceps
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:72228 ! has exposure stimulus Ophiocordyceps sinensis
relationship: RO:0002309 NCBITaxon:72228 ! has exposure stimulus Ophiocordyceps sinensis

[Term]
id: ECTO:3000137
name: exposure to Lacticaseibacillus paracasei subsp. paracasei
def: "A history of exposure to Lacticaseibacillus paracasei subsp. paracasei." []
synonym: "Lacticaseibacillus paracasei subsp. paracasei exposure" EXACT []
is_a: ECTO:3000119 ! exposure to Lacticaseibacillus paracasei
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:47714 ! has exposure stimulus Lacticaseibacillus paracasei subsp. paracasei
relationship: RO:0002309 NCBITaxon:47714 ! has exposure stimulus Lacticaseibacillus paracasei subsp. paracasei

[Term]
id: ECTO:3000138
name: exposure to Lacticaseibacillus rhamnosus GG
def: "A history of exposure to Lacticaseibacillus rhamnosus GG." []
synonym: "Lacticaseibacillus rhamnosus GG exposure" EXACT []
is_a: ECTO:3000122 ! exposure to Lacticaseibacillus rhamnosus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:568703 ! has exposure stimulus Lacticaseibacillus rhamnosus GG
relationship: RO:0002309 NCBITaxon:568703 ! has exposure stimulus Lacticaseibacillus rhamnosus GG

[Term]
id: ECTO:3000139
name: exposure to Chlamydia
def: "A history of exposure to Chlamydia." []
synonym: "Chlamydia exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:810 ! has exposure stimulus Chlamydia
relationship: RO:0002309 NCBITaxon:810 ! has exposure stimulus Chlamydia

[Term]
id: ECTO:3000140
name: exposure to Ostreid herpesvirus 1
def: "A history of exposure to Ostreid herpesvirus 1." []
synonym: "Ostreid herpesvirus 1 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:261939 ! has exposure stimulus Ostreid herpesvirus 1
relationship: RO:0002309 NCBITaxon:261939 ! has exposure stimulus Ostreid herpesvirus 1

[Term]
id: ECTO:3000141
name: exposure to Ostreid herpesvirus 1 (isolate France)
def: "A history of exposure to Ostreid herpesvirus 1 (isolate France)." []
synonym: "Ostreid herpesvirus 1 (isolate France) exposure" EXACT []
is_a: ECTO:3000140 ! exposure to Ostreid herpesvirus 1
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:654903 ! has exposure stimulus Ostreid herpesvirus 1 (isolate France)
relationship: RO:0002309 NCBITaxon:654903 ! has exposure stimulus Ostreid herpesvirus 1 (isolate France)

[Term]
id: ECTO:3000142
name: exposure to Parabacteroides distasonis
def: "A history of exposure to Parabacteroides distasonis." []
synonym: "Parabacteroides distasonis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:823 ! has exposure stimulus Parabacteroides distasonis
relationship: RO:0002309 NCBITaxon:823 ! has exposure stimulus Parabacteroides distasonis

[Term]
id: ECTO:3000143
name: exposure to Parabacteroides goldsteinii
def: "A history of exposure to Parabacteroides goldsteinii." []
synonym: "Parabacteroides goldsteinii exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:328812 ! has exposure stimulus Parabacteroides goldsteinii
relationship: RO:0002309 NCBITaxon:328812 ! has exposure stimulus Parabacteroides goldsteinii

[Term]
id: ECTO:3000144
name: exposure to Paracoccidioides brasiliensis
def: "A history of exposure to Paracoccidioides brasiliensis." []
synonym: "Paracoccidioides brasiliensis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:121759 ! has exposure stimulus Paracoccidioides brasiliensis
relationship: RO:0002309 NCBITaxon:121759 ! has exposure stimulus Paracoccidioides brasiliensis

[Term]
id: ECTO:3000145
name: exposure to Lysiphlebia japonica
def: "A history of exposure to Lysiphlebia japonica." []
synonym: "Lysiphlebia japonica exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:104022 ! has exposure stimulus Lysiphlebia japonica
relationship: RO:0002309 NCBITaxon:104022 ! has exposure stimulus Lysiphlebia japonica

[Term]
id: ECTO:3000146
name: exposure to Bacillus thuringiensis
def: "A history of exposure to Bacillus thuringiensis." []
synonym: "Bacillus thuringiensis exposure" EXACT []
is_a: ECTO:3000051 ! exposure to Bacillus <firmicutes>
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1428 ! has exposure stimulus Bacillus thuringiensis
relationship: RO:0002309 NCBITaxon:1428 ! has exposure stimulus Bacillus thuringiensis

[Term]
id: ECTO:3000147
name: exposure to Botrytis cinerea
def: "A history of exposure to Botrytis cinerea." []
synonym: "Botrytis cinerea exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:40559 ! has exposure stimulus Botrytis cinerea
relationship: RO:0002309 NCBITaxon:40559 ! has exposure stimulus Botrytis cinerea

[Term]
id: ECTO:3000148
name: exposure to Pediococcus acidilactici
def: "A history of exposure to Pediococcus acidilactici." []
synonym: "Pediococcus acidilactici exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1254 ! has exposure stimulus Pediococcus acidilactici
relationship: RO:0002309 NCBITaxon:1254 ! has exposure stimulus Pediococcus acidilactici

[Term]
id: ECTO:3000149
name: exposure to Porcine epidemic diarrhea virus
def: "A history of exposure to Porcine epidemic diarrhea virus." []
synonym: "Porcine epidemic diarrhea virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:28295 ! has exposure stimulus Porcine epidemic diarrhea virus
relationship: RO:0002309 NCBITaxon:28295 ! has exposure stimulus Porcine epidemic diarrhea virus

[Term]
id: ECTO:3000150
name: exposure to Aliivibrio fischeri ES114
def: "A history of exposure to Aliivibrio fischeri ES114." []
synonym: "Aliivibrio fischeri ES114 exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:312309 ! has exposure stimulus Aliivibrio fischeri ES114
relationship: RO:0002309 NCBITaxon:312309 ! has exposure stimulus Aliivibrio fischeri ES114

[Term]
id: ECTO:3000151
name: exposure to Phytophthora infestans
def: "A history of exposure to Phytophthora infestans." []
synonym: "Phytophthora infestans exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:4787 ! has exposure stimulus Phytophthora infestans
relationship: RO:0002309 NCBITaxon:4787 ! has exposure stimulus Phytophthora infestans

[Term]
id: ECTO:3000152
name: exposure to Plasmodiophora brassicae
def: "A history of exposure to Plasmodiophora brassicae." []
synonym: "Plasmodiophora brassicae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:37360 ! has exposure stimulus Plasmodiophora brassicae
relationship: RO:0002309 NCBITaxon:37360 ! has exposure stimulus Plasmodiophora brassicae

[Term]
id: ECTO:3000153
name: exposure to Plasmodium coatneyi
def: "A history of exposure to Plasmodium coatneyi." []
synonym: "Plasmodium coatneyi exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:208452 ! has exposure stimulus Plasmodium coatneyi
relationship: RO:0002309 NCBITaxon:208452 ! has exposure stimulus Plasmodium coatneyi

[Term]
id: ECTO:3000154
name: exposure to Plasmodium cynomolgi
def: "A history of exposure to Plasmodium cynomolgi." []
synonym: "Plasmodium cynomolgi exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5827 ! has exposure stimulus Plasmodium cynomolgi
relationship: RO:0002309 NCBITaxon:5827 ! has exposure stimulus Plasmodium cynomolgi

[Term]
id: ECTO:3000155
name: exposure to Plasmodium falciparum
def: "A history of exposure to Plasmodium falciparum." []
synonym: "Plasmodium falciparum exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5833 ! has exposure stimulus Plasmodium falciparum
relationship: RO:0002309 NCBITaxon:5833 ! has exposure stimulus Plasmodium falciparum

[Term]
id: ECTO:3000156
name: exposure to Plasmodium
def: "A history of exposure to Plasmodium <genus>." []
synonym: "Plasmodium <genus> exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5820 ! has exposure stimulus Plasmodium <genus>
relationship: RO:0002309 NCBITaxon:5820 ! has exposure stimulus Plasmodium <genus>

[Term]
id: ECTO:3000157
name: exposure to Plasmodium yoelii yoelii 17XNL
def: "A history of exposure to Plasmodium yoelii yoelii 17XNL." []
synonym: "Plasmodium yoelii yoelii 17XNL exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:352914 ! has exposure stimulus Plasmodium yoelii yoelii 17XNL
relationship: RO:0002309 NCBITaxon:352914 ! has exposure stimulus Plasmodium yoelii yoelii 17XNL

[Term]
id: ECTO:3000158
name: exposure to Plasmodium sp. vivax/simium
def: "A history of exposure to Plasmodium sp. vivax/simium." []
synonym: "Plasmodium sp. vivax/simium exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2052898 ! has exposure stimulus Plasmodium sp. vivax/simium
relationship: RO:0002309 NCBITaxon:2052898 ! has exposure stimulus Plasmodium sp. vivax/simium

[Term]
id: ECTO:3000159
name: exposure to Plutella xylostella
def: "A history of exposure to Plutella xylostella." []
synonym: "Plutella xylostella exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:51655 ! has exposure stimulus Plutella xylostella
relationship: RO:0002309 NCBITaxon:51655 ! has exposure stimulus Plutella xylostella

[Term]
id: ECTO:3000160
name: exposure to Ligilactobacillus salivarius
def: "A history of exposure to Ligilactobacillus salivarius." []
synonym: "Ligilactobacillus salivarius exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1624 ! has exposure stimulus Ligilactobacillus salivarius
relationship: RO:0002309 NCBITaxon:1624 ! has exposure stimulus Ligilactobacillus salivarius

[Term]
id: ECTO:3000161
name: exposure to Pseudogymnoascus destructans
def: "A history of exposure to Pseudogymnoascus destructans." []
synonym: "Pseudogymnoascus destructans exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:655981 ! has exposure stimulus Pseudogymnoascus destructans
relationship: RO:0002309 NCBITaxon:655981 ! has exposure stimulus Pseudogymnoascus destructans

[Term]
id: ECTO:3000162
name: exposure to Pseudomonas aeruginosa
def: "A history of exposure to Pseudomonas aeruginosa." []
synonym: "Pseudomonas aeruginosa exposure" EXACT []
is_a: ECTO:3000296 ! exposure to Pseudomonas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:287 ! has exposure stimulus Pseudomonas aeruginosa
relationship: RO:0002309 NCBITaxon:287 ! has exposure stimulus Pseudomonas aeruginosa

[Term]
id: ECTO:3000163
name: exposure to Pseudomonas syringae pv. tomato str. DC3000
def: "A history of exposure to Pseudomonas syringae pv. tomato str. DC3000." []
synonym: "Pseudomonas syringae pv. tomato str. DC3000 exposure" EXACT []
is_a: ECTO:3000296 ! exposure to Pseudomonas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:223283 ! has exposure stimulus Pseudomonas syringae pv. tomato str. DC3000
relationship: RO:0002309 NCBITaxon:223283 ! has exposure stimulus Pseudomonas syringae pv. tomato str. DC3000

[Term]
id: ECTO:3000164
name: exposure to Suid alphaherpesvirus 1
def: "A history of exposure to Suid alphaherpesvirus 1." []
synonym: "Suid alphaherpesvirus 1 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10345 ! has exposure stimulus Suid alphaherpesvirus 1
relationship: RO:0002309 NCBITaxon:10345 ! has exposure stimulus Suid alphaherpesvirus 1

[Term]
id: ECTO:3000165
name: exposure to Rhizoctonia solani
def: "A history of exposure to Rhizoctonia solani." []
synonym: "Rhizoctonia solani exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:456999 ! has exposure stimulus Rhizoctonia solani
relationship: RO:0002309 NCBITaxon:456999 ! has exposure stimulus Rhizoctonia solani

[Term]
id: ECTO:3000166
name: exposure to Rhizophagus intraradices
def: "A history of exposure to Rhizophagus intraradices." []
synonym: "Rhizophagus intraradices exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:4876 ! has exposure stimulus Rhizophagus intraradices
relationship: RO:0002309 NCBITaxon:4876 ! has exposure stimulus Rhizophagus intraradices

[Term]
id: ECTO:3000167
name: exposure to Rickettsia parkeri
def: "A history of exposure to Rickettsia parkeri." []
synonym: "Rickettsia parkeri exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:35792 ! has exposure stimulus Rickettsia parkeri
relationship: RO:0002309 NCBITaxon:35792 ! has exposure stimulus Rickettsia parkeri

[Term]
id: ECTO:3000168
name: exposure to Trichoderma virens
def: "A history of exposure to Trichoderma virens." []
synonym: "Trichoderma virens exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:29875 ! has exposure stimulus Trichoderma virens
relationship: RO:0002309 NCBITaxon:29875 ! has exposure stimulus Trichoderma virens

[Term]
id: ECTO:3000169
name: exposure to Roseburia inulinivorans
def: "A history of exposure to Roseburia inulinivorans." []
synonym: "Roseburia inulinivorans exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:360807 ! has exposure stimulus Roseburia inulinivorans
relationship: RO:0002309 NCBITaxon:360807 ! has exposure stimulus Roseburia inulinivorans

[Term]
id: ECTO:3000170
name: exposure to Rosenbergiella nectarea
def: "A history of exposure to Rosenbergiella nectarea." []
synonym: "Rosenbergiella nectarea exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:988801 ! has exposure stimulus Rosenbergiella nectarea
relationship: RO:0002309 NCBITaxon:988801 ! has exposure stimulus Rosenbergiella nectarea

[Term]
id: ECTO:3000171
name: exposure to Salmonella enterica
def: "A history of exposure to Salmonella enterica." []
synonym: "Salmonella enterica exposure" EXACT []
is_a: ECTO:3000008 ! exposure to Salmonella
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:28901 ! has exposure stimulus Salmonella enterica
relationship: RO:0002309 NCBITaxon:28901 ! has exposure stimulus Salmonella enterica

[Term]
id: ECTO:3000172
name: exposure to Salmonella enterica subsp. enterica serovar Typhimurium
def: "A history of exposure to Salmonella enterica subsp. enterica serovar Typhimurium." []
synonym: "Salmonella enterica subsp. enterica serovar Typhimurium exposure" EXACT []
is_a: ECTO:3000171 ! exposure to Salmonella enterica
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:90371 ! has exposure stimulus Salmonella enterica subsp. enterica serovar Typhimurium
relationship: RO:0002309 NCBITaxon:90371 ! has exposure stimulus Salmonella enterica subsp. enterica serovar Typhimurium

[Term]
id: ECTO:3000173
name: exposure to Severe acute respiratory syndrome coronavirus 2
def: "A history of exposure to Severe acute respiratory syndrome coronavirus 2." []
synonym: "Severe acute respiratory syndrome coronavirus 2 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2697049 ! has exposure stimulus Severe acute respiratory syndrome coronavirus 2
relationship: RO:0002309 NCBITaxon:2697049 ! has exposure stimulus Severe acute respiratory syndrome coronavirus 2

[Term]
id: ECTO:3000174
name: exposure to Schistosoma mansoni
def: "A history of exposure to Schistosoma mansoni." []
synonym: "Schistosoma mansoni exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6183 ! has exposure stimulus Schistosoma mansoni
relationship: RO:0002309 NCBITaxon:6183 ! has exposure stimulus Schistosoma mansoni

[Term]
id: ECTO:3000175
name: exposure to Simian immunodeficiency virus - mac
def: "A history of exposure to Simian immunodeficiency virus - mac." []
synonym: "Simian immunodeficiency virus - mac exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11711 ! has exposure stimulus Simian immunodeficiency virus - mac
relationship: RO:0002309 NCBITaxon:11711 ! has exposure stimulus Simian immunodeficiency virus - mac

[Term]
id: ECTO:3000176
name: exposure to Aspergillus brasiliensis
def: "A history of exposure to Aspergillus brasiliensis." []
synonym: "Aspergillus brasiliensis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:319629 ! has exposure stimulus Aspergillus brasiliensis
relationship: RO:0002309 NCBITaxon:319629 ! has exposure stimulus Aspergillus brasiliensis

[Term]
id: ECTO:3000177
name: exposure to Streptococcus agalactiae
def: "A history of exposure to Streptococcus agalactiae." []
synonym: "Streptococcus agalactiae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1311 ! has exposure stimulus Streptococcus agalactiae
relationship: RO:0002309 NCBITaxon:1311 ! has exposure stimulus Streptococcus agalactiae

[Term]
id: ECTO:3000178
name: exposure to Streptococcus anginosus
def: "A history of exposure to Streptococcus anginosus." []
synonym: "Streptococcus anginosus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1328 ! has exposure stimulus Streptococcus anginosus
relationship: RO:0002309 NCBITaxon:1328 ! has exposure stimulus Streptococcus anginosus

[Term]
id: ECTO:3000179
name: exposure to Streptococcus pneumoniae
def: "A history of exposure to Streptococcus pneumoniae." []
synonym: "Streptococcus pneumoniae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1313 ! has exposure stimulus Streptococcus pneumoniae
relationship: RO:0002309 NCBITaxon:1313 ! has exposure stimulus Streptococcus pneumoniae

[Term]
id: ECTO:3000180
name: exposure to Streptococcus salivarius
def: "A history of exposure to Streptococcus salivarius." []
synonym: "Streptococcus salivarius exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1304 ! has exposure stimulus Streptococcus salivarius
relationship: RO:0002309 NCBITaxon:1304 ! has exposure stimulus Streptococcus salivarius

[Term]
id: ECTO:3000181
name: exposure to Symbiodinium
def: "A history of exposure to Symbiodinium." []
synonym: "Symbiodinium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2949 ! has exposure stimulus Symbiodinium
relationship: RO:0002309 NCBITaxon:2949 ! has exposure stimulus Symbiodinium

[Term]
id: ECTO:3000182
name: exposure to Enterobacteria phage T7.1
def: "A history of exposure to Enterobacteria phage T7.1." []
synonym: "Enterobacteria phage T7.1 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:338882 ! has exposure stimulus Enterobacteria phage T7.1
relationship: RO:0002309 NCBITaxon:338882 ! has exposure stimulus Enterobacteria phage T7.1

[Term]
id: ECTO:3000183
name: exposure to Tick-borne encephalitis virus
def: "A history of exposure to Tick-borne encephalitis virus." []
synonym: "Tick-borne encephalitis virus exposure" EXACT []
is_a: ECTO:3000074 ! exposure to Flavivirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11084 ! has exposure stimulus Tick-borne encephalitis virus
relationship: RO:0002309 NCBITaxon:11084 ! has exposure stimulus Tick-borne encephalitis virus

[Term]
id: ECTO:3000184
name: exposure to Tomato mottle mosaic virus
def: "A history of exposure to Tomato mottle mosaic virus." []
synonym: "Tomato mottle mosaic virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1391702 ! has exposure stimulus Tomato mottle mosaic virus
relationship: RO:0002309 NCBITaxon:1391702 ! has exposure stimulus Tomato mottle mosaic virus

[Term]
id: ECTO:3000185
name: exposure to Toxocara canis
def: "A history of exposure to Toxocara canis." []
synonym: "Toxocara canis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6265 ! has exposure stimulus Toxocara canis
relationship: RO:0002309 NCBITaxon:6265 ! has exposure stimulus Toxocara canis

[Term]
id: ECTO:3000186
name: exposure to Trypanosoma congolense
def: "A history of exposure to Trypanosoma congolense." []
synonym: "Trypanosoma congolense exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5692 ! has exposure stimulus Trypanosoma congolense
relationship: RO:0002309 NCBITaxon:5692 ! has exposure stimulus Trypanosoma congolense

[Term]
id: ECTO:3000187
name: exposure to Trypanosoma cruzi
def: "A history of exposure to Trypanosoma cruzi." []
synonym: "Trypanosoma cruzi exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5693 ! has exposure stimulus Trypanosoma cruzi
relationship: RO:0002309 NCBITaxon:5693 ! has exposure stimulus Trypanosoma cruzi

[Term]
id: ECTO:3000188
name: exposure to Varroa destructor
def: "A history of exposure to Varroa destructor." []
synonym: "Varroa destructor exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:109461 ! has exposure stimulus Varroa destructor
relationship: RO:0002309 NCBITaxon:109461 ! has exposure stimulus Varroa destructor

[Term]
id: ECTO:3000189
name: exposure to Vesicular stomatitis virus
def: "A history of exposure to Vesicular stomatitis virus." []
synonym: "Vesicular stomatitis virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11276 ! has exposure stimulus Vesicular stomatitis virus
relationship: RO:0002309 NCBITaxon:11276 ! has exposure stimulus Vesicular stomatitis virus

[Term]
id: ECTO:3000190
name: exposure to Vibrio parahaemolyticus
def: "A history of exposure to Vibrio parahaemolyticus." []
synonym: "Vibrio parahaemolyticus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:670 ! has exposure stimulus Vibrio parahaemolyticus
relationship: RO:0002309 NCBITaxon:670 ! has exposure stimulus Vibrio parahaemolyticus

[Term]
id: ECTO:3000191
name: exposure to Marine virus AFVG_15N00002
def: "A history of exposure to Marine virus AFVG_15N00002." []
synonym: "Marine virus AFVG_15N00002 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2573277 ! has exposure stimulus Marine virus AFVG_15N00002
relationship: RO:0002309 NCBITaxon:2573277 ! has exposure stimulus Marine virus AFVG_15N00002

[Term]
id: ECTO:3000192
name: exposure to Wolbachia pipientis wMelPop
def: "A history of exposure to Wolbachia pipientis wMelPop." []
synonym: "Wolbachia pipientis wMelPop exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1317678 ! has exposure stimulus Wolbachia pipientis wMelPop
relationship: RO:0002309 NCBITaxon:1317678 ! has exposure stimulus Wolbachia pipientis wMelPop

[Term]
id: ECTO:3000193
name: exposure to Xanthomonas campestris pv. campestris
def: "A history of exposure to Xanthomonas campestris pv. campestris." []
synonym: "Xanthomonas campestris pv. campestris exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:340 ! has exposure stimulus Xanthomonas campestris pv. campestris
relationship: RO:0002309 NCBITaxon:340 ! has exposure stimulus Xanthomonas campestris pv. campestris

[Term]
id: ECTO:3000194
name: exposure to Xanthomonas oryzae pv. oryzae
def: "A history of exposure to Xanthomonas oryzae pv. oryzae." []
synonym: "Xanthomonas oryzae pv. oryzae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:64187 ! has exposure stimulus Xanthomonas oryzae pv. oryzae
relationship: RO:0002309 NCBITaxon:64187 ! has exposure stimulus Xanthomonas oryzae pv. oryzae

[Term]
id: ECTO:3000195
name: exposure to Akkermansia
def: "A history of exposure to Akkermansia." []
synonym: "Akkermansia exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:239934 ! has exposure stimulus Akkermansia
relationship: RO:0002309 NCBITaxon:239934 ! has exposure stimulus Akkermansia

[Term]
id: ECTO:3000197
name: exposure to Bifidobacterium longum
def: "A history of exposure to Bifidobacterium longum." []
synonym: "Bifidobacterium longum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:216816 ! has exposure stimulus Bifidobacterium longum
relationship: RO:0002309 NCBITaxon:216816 ! has exposure stimulus Bifidobacterium longum

[Term]
id: ECTO:3000198
name: exposure to Burkholderia
def: "A history of exposure to Burkholderia." []
synonym: "Burkholderia exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:32008 ! has exposure stimulus Burkholderia
relationship: RO:0002309 NCBITaxon:32008 ! has exposure stimulus Burkholderia

[Term]
id: ECTO:3000199
name: exposure to Campylobacter coli
def: "A history of exposure to Campylobacter coli." []
synonym: "Campylobacter coli exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:195 ! has exposure stimulus Campylobacter coli
relationship: RO:0002309 NCBITaxon:195 ! has exposure stimulus Campylobacter coli

[Term]
id: ECTO:3000201
name: exposure to Chikungunya virus
def: "A history of exposure to Chikungunya virus." []
synonym: "Chikungunya virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:37124 ! has exposure stimulus Chikungunya virus
relationship: RO:0002309 NCBITaxon:37124 ! has exposure stimulus Chikungunya virus

[Term]
id: ECTO:3000202
name: exposure to Clonorchis sinensis
def: "A history of exposure to Clonorchis sinensis." []
synonym: "Clonorchis sinensis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:79923 ! has exposure stimulus Clonorchis sinensis
relationship: RO:0002309 NCBITaxon:79923 ! has exposure stimulus Clonorchis sinensis

[Term]
id: ECTO:3000204
name: exposure to Clostridium butyricum
def: "A history of exposure to Clostridium butyricum." []
synonym: "Clostridium butyricum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1492 ! has exposure stimulus Clostridium butyricum
relationship: RO:0002309 NCBITaxon:1492 ! has exposure stimulus Clostridium butyricum

[Term]
id: ECTO:3000205
name: exposure to Cytomegalovirus
def: "A history of exposure to Cytomegalovirus." []
synonym: "Cytomegalovirus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10358 ! has exposure stimulus Cytomegalovirus
relationship: RO:0002309 NCBITaxon:10358 ! has exposure stimulus Cytomegalovirus

[Term]
id: ECTO:3000207
name: exposure to Enterobacter ludwigii
def: "A history of exposure to Enterobacter ludwigii." []
synonym: "Enterobacter ludwigii exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:299767 ! has exposure stimulus Enterobacter ludwigii
relationship: RO:0002309 NCBITaxon:299767 ! has exposure stimulus Enterobacter ludwigii

[Term]
id: ECTO:3000209
name: exposure to Enterococcus faecium
def: "A history of exposure to Enterococcus faecium." []
synonym: "Enterococcus faecium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1352 ! has exposure stimulus Enterococcus faecium
relationship: RO:0002309 NCBITaxon:1352 ! has exposure stimulus Enterococcus faecium

[Term]
id: ECTO:3000211
name: exposure to Hendra virus
def: "A history of exposure to Henipavirus hendraense." []
synonym: "Henipavirus hendraense exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:3052223 ! has exposure stimulus Henipavirus hendraense
relationship: RO:0002309 NCBITaxon:3052223 ! has exposure stimulus Henipavirus hendraense

[Term]
id: ECTO:3000212
name: exposure to Human papillomavirus
def: "A history of exposure to Human papillomavirus." []
synonym: "Human papillomavirus exposure" EXACT []
is_a: ECTO:3000004 ! exposure to Papillomaviridae
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10566 ! has exposure stimulus Human papillomavirus
relationship: RO:0002309 NCBITaxon:10566 ! has exposure stimulus Human papillomavirus

[Term]
id: ECTO:3000214
name: exposure to Respiratory syncytial virus
def: "A history of exposure to Respiratory syncytial virus." []
synonym: "Respiratory syncytial virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12814 ! has exposure stimulus Respiratory syncytial virus
relationship: RO:0002309 NCBITaxon:12814 ! has exposure stimulus Respiratory syncytial virus

[Term]
id: ECTO:3000216
name: exposure to Lacticaseibacillus casei
def: "A history of exposure to Lacticaseibacillus casei." []
synonym: "Lacticaseibacillus casei exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1582 ! has exposure stimulus Lacticaseibacillus casei
relationship: RO:0002309 NCBITaxon:1582 ! has exposure stimulus Lacticaseibacillus casei

[Term]
id: ECTO:3000217
name: exposure to Lactobacillus acidophilus
def: "A history of exposure to Lactobacillus acidophilus." []
synonym: "Lactobacillus acidophilus exposure" EXACT []
is_a: ECTO:3000092 ! exposure to Lactobacillus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1579 ! has exposure stimulus Lactobacillus acidophilus
relationship: RO:0002309 NCBITaxon:1579 ! has exposure stimulus Lactobacillus acidophilus

[Term]
id: ECTO:3000218
name: exposure to Lassa virus
def: "A history of exposure to Mammarenavirus lassaense." []
synonym: "Mammarenavirus lassaense exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:3052310 ! has exposure stimulus Mammarenavirus lassaense
relationship: RO:0002309 NCBITaxon:3052310 ! has exposure stimulus Mammarenavirus lassaense

[Term]
id: ECTO:3000219
name: exposure to Limosilactobacillus reuteri
def: "A history of exposure to Limosilactobacillus reuteri." []
synonym: "Limosilactobacillus reuteri exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1598 ! has exposure stimulus Limosilactobacillus reuteri
relationship: RO:0002309 NCBITaxon:1598 ! has exposure stimulus Limosilactobacillus reuteri

[Term]
id: ECTO:3000220
name: exposure to Mycoplasmoides pneumoniae
def: "A history of exposure to Mycoplasmoides pneumoniae." []
synonym: "Mycoplasmoides pneumoniae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2104 ! has exposure stimulus Mycoplasmoides pneumoniae
relationship: RO:0002309 NCBITaxon:2104 ! has exposure stimulus Mycoplasmoides pneumoniae

[Term]
id: ECTO:3000221
name: exposure to Myxobolus
def: "A history of exposure to Myxobolus." []
synonym: "Myxobolus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:35588 ! has exposure stimulus Myxobolus
relationship: RO:0002309 NCBITaxon:35588 ! has exposure stimulus Myxobolus

[Term]
id: ECTO:3000222
name: exposure to Ophiocordyceps
def: "A history of exposure to Ophiocordyceps." []
synonym: "Ophiocordyceps exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:474995 ! has exposure stimulus Ophiocordyceps
relationship: RO:0002309 NCBITaxon:474995 ! has exposure stimulus Ophiocordyceps

[Term]
id: ECTO:3000228
name: exposure to Plasmodium vivax
def: "A history of exposure to Plasmodium vivax." []
synonym: "Plasmodium vivax exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5855 ! has exposure stimulus Plasmodium vivax
relationship: RO:0002309 NCBITaxon:5855 ! has exposure stimulus Plasmodium vivax

[Term]
id: ECTO:3000229
name: exposure to Rhinovirus A
def: "A history of exposure to Rhinovirus A." []
synonym: "Rhinovirus A exposure" EXACT []
is_a: ECTO:3000002 ! exposure to Enterovirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:147711 ! has exposure stimulus Rhinovirus A
relationship: RO:0002309 NCBITaxon:147711 ! has exposure stimulus Rhinovirus A

[Term]
id: ECTO:3000237
name: exposure to Shigella flexneri
def: "A history of exposure to Shigella flexneri." []
synonym: "Shigella flexneri exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:623 ! has exposure stimulus Shigella flexneri
relationship: RO:0002309 NCBITaxon:623 ! has exposure stimulus Shigella flexneri

[Term]
id: ECTO:3000242
name: exposure to Yersinia ruckeri
def: "A history of exposure to Yersinia ruckeri." []
synonym: "Yersinia ruckeri exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:29486 ! has exposure stimulus Yersinia ruckeri
relationship: RO:0002309 NCBITaxon:29486 ! has exposure stimulus Yersinia ruckeri

[Term]
id: ECTO:3000243
name: exposure to Plasmopara viticola
def: "A history of exposure to Plasmopara viticola." []
synonym: "Plasmopara viticola exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:143451 ! has exposure stimulus Plasmopara viticola
relationship: RO:0002309 NCBITaxon:143451 ! has exposure stimulus Plasmopara viticola

[Term]
id: ECTO:3000244
name: exposure to Haemophilus influenzae
def: "A history of exposure to Haemophilus influenzae." []
synonym: "Haemophilus influenzae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:727 ! has exposure stimulus Haemophilus influenzae
relationship: RO:0002309 NCBITaxon:727 ! has exposure stimulus Haemophilus influenzae

[Term]
id: ECTO:3000245
name: exposure to Borreliella burgdorferi
def: "A history of exposure to Borreliella burgdorferi." []
synonym: "Borreliella burgdorferi exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:139 ! has exposure stimulus Borreliella burgdorferi
relationship: RO:0002309 NCBITaxon:139 ! has exposure stimulus Borreliella burgdorferi

[Term]
id: ECTO:3000246
name: exposure to Edwardsiella piscicida
def: "A history of exposure to Edwardsiella piscicida." []
synonym: "Edwardsiella piscicida exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1263550 ! has exposure stimulus Edwardsiella piscicida
relationship: RO:0002309 NCBITaxon:1263550 ! has exposure stimulus Edwardsiella piscicida

[Term]
id: ECTO:3000247
name: exposure to Bacteroides uniformis
def: "A history of exposure to Bacteroides uniformis." []
synonym: "Bacteroides uniformis exposure" EXACT []
is_a: ECTO:3000085 ! exposure to Bacteroides
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:820 ! has exposure stimulus Bacteroides uniformis
relationship: RO:0002309 NCBITaxon:820 ! has exposure stimulus Bacteroides uniformis

[Term]
id: ECTO:3000248
name: exposure to Batrachochytrium dendrobatidis
def: "A history of exposure to Batrachochytrium dendrobatidis." []
synonym: "Batrachochytrium dendrobatidis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:109871 ! has exposure stimulus Batrachochytrium dendrobatidis
relationship: RO:0002309 NCBITaxon:109871 ! has exposure stimulus Batrachochytrium dendrobatidis

[Term]
id: ECTO:3000249
name: exposure to Bifidobacterium animalis subsp. lactis
def: "A history of exposure to Bifidobacterium animalis subsp. lactis." []
synonym: "Bifidobacterium animalis subsp. lactis exposure" EXACT []
is_a: ECTO:3000311 ! exposure to Bifidobacterium animalis
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:302911 ! has exposure stimulus Bifidobacterium animalis subsp. lactis
relationship: RO:0002309 NCBITaxon:302911 ! has exposure stimulus Bifidobacterium animalis subsp. lactis

[Term]
id: ECTO:3000250
name: exposure to Cytobacillus oceanisediminis
def: "A history of exposure to Cytobacillus oceanisediminis." []
synonym: "Cytobacillus oceanisediminis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:665099 ! has exposure stimulus Cytobacillus oceanisediminis
relationship: RO:0002309 NCBITaxon:665099 ! has exposure stimulus Cytobacillus oceanisediminis

[Term]
id: ECTO:3000251
name: exposure to Bombyx mori nucleopolyhedrovirus
def: "A history of exposure to Bombyx mori nucleopolyhedrovirus." []
synonym: "Bombyx mori nucleopolyhedrovirus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:271108 ! has exposure stimulus Bombyx mori nucleopolyhedrovirus
relationship: RO:0002309 NCBITaxon:271108 ! has exposure stimulus Bombyx mori nucleopolyhedrovirus

[Term]
id: ECTO:3000252
name: exposure to Nilaparvata lugens
def: "A history of exposure to Nilaparvata lugens." []
synonym: "Nilaparvata lugens exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:108931 ! has exposure stimulus Nilaparvata lugens
relationship: RO:0002309 NCBITaxon:108931 ! has exposure stimulus Nilaparvata lugens

[Term]
id: ECTO:3000253
name: exposure to Haematobia irritans exigua
def: "A history of exposure to Haematobia irritans exigua." []
synonym: "Haematobia irritans exigua exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:34678 ! has exposure stimulus Haematobia irritans exigua
relationship: RO:0002309 NCBITaxon:34678 ! has exposure stimulus Haematobia irritans exigua

[Term]
id: ECTO:3000254
name: exposure to Burkholderia contaminans
def: "A history of exposure to Burkholderia contaminans." []
synonym: "Burkholderia contaminans exposure" EXACT []
is_a: ECTO:3000198 ! exposure to Burkholderia
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:488447 ! has exposure stimulus Burkholderia contaminans
relationship: RO:0002309 NCBITaxon:488447 ! has exposure stimulus Burkholderia contaminans

[Term]
id: ECTO:3000255
name: exposure to Campylobacter jejuni
def: "A history of exposure to Campylobacter jejuni." []
synonym: "Campylobacter jejuni exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:197 ! has exposure stimulus Campylobacter jejuni
relationship: RO:0002309 NCBITaxon:197 ! has exposure stimulus Campylobacter jejuni

[Term]
id: ECTO:3000256
name: exposure to Canid alphaherpesvirus 1
def: "A history of exposure to Canid alphaherpesvirus 1." []
synonym: "Canid alphaherpesvirus 1 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:170325 ! has exposure stimulus Canid alphaherpesvirus 1
relationship: RO:0002309 NCBITaxon:170325 ! has exposure stimulus Canid alphaherpesvirus 1

[Term]
id: ECTO:3000257
name: exposure to Cetobacterium somerae
def: "A history of exposure to Cetobacterium somerae." []
synonym: "Cetobacterium somerae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:188913 ! has exposure stimulus Cetobacterium somerae
relationship: RO:0002309 NCBITaxon:188913 ! has exposure stimulus Cetobacterium somerae

[Term]
id: ECTO:3000258
name: exposure to Chlamydia trachomatis
def: "A history of exposure to Chlamydia trachomatis." []
synonym: "Chlamydia trachomatis exposure" EXACT []
is_a: ECTO:3000139 ! exposure to Chlamydia
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:813 ! has exposure stimulus Chlamydia trachomatis
relationship: RO:0002309 NCBITaxon:813 ! has exposure stimulus Chlamydia trachomatis

[Term]
id: ECTO:3000259
name: exposure to Christensenella intestinihominis
def: "A history of exposure to Christensenella intestinihominis." []
synonym: "Christensenella intestinihominis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1851429 ! has exposure stimulus Christensenella intestinihominis
relationship: RO:0002309 NCBITaxon:1851429 ! has exposure stimulus Christensenella intestinihominis

[Term]
id: ECTO:3000260
name: exposure to Acetobacter fabarum
def: "A history of exposure to Acetobacter fabarum." []
synonym: "Acetobacter fabarum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:483199 ! has exposure stimulus Acetobacter fabarum
relationship: RO:0002309 NCBITaxon:483199 ! has exposure stimulus Acetobacter fabarum

[Term]
id: ECTO:3000261
name: exposure to Eggerthella lenta
def: "A history of exposure to Eggerthella lenta." []
synonym: "Eggerthella lenta exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:84112 ! has exposure stimulus Eggerthella lenta
relationship: RO:0002309 NCBITaxon:84112 ! has exposure stimulus Eggerthella lenta

[Term]
id: ECTO:3000262
name: exposure to Cryptococcus neoformans
def: "A history of exposure to Cryptococcus neoformans." []
synonym: "Cryptococcus neoformans exposure" EXACT []
is_a: ECTO:3000055 ! exposure to Cryptococcus neoformans species complex
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5207 ! has exposure stimulus Cryptococcus neoformans
relationship: RO:0002309 NCBITaxon:5207 ! has exposure stimulus Cryptococcus neoformans

[Term]
id: ECTO:3000263
name: exposure to Dengue virus
def: "A history of exposure to Dengue virus." []
synonym: "Dengue virus exposure" EXACT []
is_a: ECTO:3000074 ! exposure to Flavivirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12637 ! has exposure stimulus Dengue virus
relationship: RO:0002309 NCBITaxon:12637 ! has exposure stimulus Dengue virus

[Term]
id: ECTO:3000264
name: exposure to Dubosiella newyorkensis
def: "A history of exposure to Dubosiella newyorkensis." []
synonym: "Dubosiella newyorkensis exposure" EXACT []
is_a: ECTO:3000061 ! exposure to Dubosiella
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1862672 ! has exposure stimulus Dubosiella newyorkensis
relationship: RO:0002309 NCBITaxon:1862672 ! has exposure stimulus Dubosiella newyorkensis

[Term]
id: ECTO:3000265
name: exposure to Paxillus involutus
def: "A history of exposure to Paxillus involutus." []
synonym: "Paxillus involutus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:71150 ! has exposure stimulus Paxillus involutus
relationship: RO:0002309 NCBITaxon:71150 ! has exposure stimulus Paxillus involutus

[Term]
id: ECTO:3000266
name: exposure to Veillonella
def: "A history of exposure to Veillonella." []
synonym: "Veillonella exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:29465 ! has exposure stimulus Veillonella
relationship: RO:0002309 NCBITaxon:29465 ! has exposure stimulus Veillonella

[Term]
id: ECTO:3000267
name: exposure to Edwardsiella tarda
def: "A history of exposure to Edwardsiella tarda." []
synonym: "Edwardsiella tarda exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:636 ! has exposure stimulus Edwardsiella tarda
relationship: RO:0002309 NCBITaxon:636 ! has exposure stimulus Edwardsiella tarda

[Term]
id: ECTO:3000268
name: exposure to Cladosporium cladosporioides
def: "A history of exposure to Cladosporium cladosporioides." []
synonym: "Cladosporium cladosporioides exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:29917 ! has exposure stimulus Cladosporium cladosporioides
relationship: RO:0002309 NCBITaxon:29917 ! has exposure stimulus Cladosporium cladosporioides

[Term]
id: ECTO:3000269
name: exposure to Strigomonas culicis
def: "A history of exposure to Strigomonas culicis." []
synonym: "Strigomonas culicis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:28005 ! has exposure stimulus Strigomonas culicis
relationship: RO:0002309 NCBITaxon:28005 ! has exposure stimulus Strigomonas culicis

[Term]
id: ECTO:3000270
name: exposure to Entamoeba histolytica
def: "A history of exposure to Entamoeba histolytica." []
synonym: "Entamoeba histolytica exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5759 ! has exposure stimulus Entamoeba histolytica
relationship: RO:0002309 NCBITaxon:5759 ! has exposure stimulus Entamoeba histolytica

[Term]
id: ECTO:3000271
name: exposure to Enterococcus avium
def: "A history of exposure to Enterococcus avium." []
synonym: "Enterococcus avium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:33945 ! has exposure stimulus Enterococcus avium
relationship: RO:0002309 NCBITaxon:33945 ! has exposure stimulus Enterococcus avium

[Term]
id: ECTO:3000272
name: exposure to Human herpesvirus 4 type 1
def: "A history of exposure to Human herpesvirus 4 type 1." []
synonym: "Human herpesvirus 4 type 1 exposure" EXACT []
is_a: ECTO:3000273 ! exposure to human gammaherpesvirus 4
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:36352 ! has exposure stimulus Human herpesvirus 4 type 1
relationship: RO:0002309 NCBITaxon:36352 ! has exposure stimulus Human herpesvirus 4 type 1

[Term]
id: ECTO:3000273
name: exposure to human gammaherpesvirus 4
def: "A history of exposure to human gammaherpesvirus 4." []
synonym: "human gammaherpesvirus 4 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10376 ! has exposure stimulus human gammaherpesvirus 4
relationship: RO:0002309 NCBITaxon:10376 ! has exposure stimulus human gammaherpesvirus 4

[Term]
id: ECTO:3000274
name: exposure to Orthopoxvirus vaccinia
def: "A history of exposure to Orthopoxvirus vaccinia." []
synonym: "Orthopoxvirus vaccinia exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:10245 ! has exposure stimulus Orthopoxvirus vaccinia
relationship: RO:0002309 NCBITaxon:10245 ! has exposure stimulus Orthopoxvirus vaccinia

[Term]
id: ECTO:3000275
name: exposure to Breviolum minutum
def: "A history of exposure to Breviolum minutum." []
synonym: "Breviolum minutum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2499525 ! has exposure stimulus Breviolum minutum
relationship: RO:0002309 NCBITaxon:2499525 ! has exposure stimulus Breviolum minutum

[Term]
id: ECTO:3000276
name: exposure to Durusdinium trenchii
def: "A history of exposure to Durusdinium trenchii." []
synonym: "Durusdinium trenchii exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1381693 ! has exposure stimulus Durusdinium trenchii
relationship: RO:0002309 NCBITaxon:1381693 ! has exposure stimulus Durusdinium trenchii

[Term]
id: ECTO:3000277
name: exposure to Plasmodium berghei
def: "A history of exposure to Plasmodium berghei." []
synonym: "Plasmodium berghei exposure" EXACT []
is_a: ECTO:3000156 ! exposure to Plasmodium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5821 ! has exposure stimulus Plasmodium berghei
relationship: RO:0002309 NCBITaxon:5821 ! has exposure stimulus Plasmodium berghei

[Term]
id: ECTO:3000278
name: exposure to Fasciola hepatica
def: "A history of exposure to Fasciola hepatica." []
synonym: "Fasciola hepatica exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6192 ! has exposure stimulus Fasciola hepatica
relationship: RO:0002309 NCBITaxon:6192 ! has exposure stimulus Fasciola hepatica

[Term]
id: ECTO:3000279
name: exposure to West Nile virus
def: "A history of exposure to West Nile virus." []
synonym: "West Nile virus exposure" EXACT []
is_a: ECTO:3000074 ! exposure to Flavivirus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:11082 ! has exposure stimulus West Nile virus
relationship: RO:0002309 NCBITaxon:11082 ! has exposure stimulus West Nile virus

[Term]
id: ECTO:3000280
name: exposure to Calanus finmarchicus
def: "A history of exposure to Calanus finmarchicus." []
synonym: "Calanus finmarchicus exposure" EXACT []
is_a: ECTO:3000089 ! exposure to Calanus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6837 ! has exposure stimulus Calanus finmarchicus
relationship: RO:0002309 NCBITaxon:6837 ! has exposure stimulus Calanus finmarchicus

[Term]
id: ECTO:3000281
name: exposure to Centropages typicus
def: "A history of exposure to Centropages typicus." []
synonym: "Centropages typicus exposure" EXACT []
is_a: ECTO:3000090 ! exposure to Centropages
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:463189 ! has exposure stimulus Centropages typicus
relationship: RO:0002309 NCBITaxon:463189 ! has exposure stimulus Centropages typicus

[Term]
id: ECTO:3000282
name: exposure to Lactobacillus apis
def: "A history of exposure to Lactobacillus apis." []
synonym: "Lactobacillus apis exposure" EXACT []
is_a: ECTO:3000092 ! exposure to Lactobacillus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:303541 ! has exposure stimulus Lactobacillus apis
relationship: RO:0002309 NCBITaxon:303541 ! has exposure stimulus Lactobacillus apis

[Term]
id: ECTO:3000283
name: exposure to Bacteroides ovatus
def: "A history of exposure to Bacteroides ovatus." []
synonym: "Bacteroides ovatus exposure" EXACT []
is_a: ECTO:3000085 ! exposure to Bacteroides
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:28116 ! has exposure stimulus Bacteroides ovatus
relationship: RO:0002309 NCBITaxon:28116 ! has exposure stimulus Bacteroides ovatus

[Term]
id: ECTO:3000284
name: exposure to Hepacivirus hominis
def: "A history of exposure to Orthohepacivirus hominis." []
synonym: "Orthohepacivirus hominis exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:3052230 ! has exposure stimulus Orthohepacivirus hominis
relationship: RO:0002309 NCBITaxon:3052230 ! has exposure stimulus Orthohepacivirus hominis

[Term]
id: ECTO:3000285
name: exposure to Lymantria dispar
def: "A history of exposure to Lymantria dispar." []
synonym: "Lymantria dispar exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:13123 ! has exposure stimulus Lymantria dispar
relationship: RO:0002309 NCBITaxon:13123 ! has exposure stimulus Lymantria dispar

[Term]
id: ECTO:3000286
name: exposure to Sesamia nonagrioides
def: "A history of exposure to Sesamia nonagrioides." []
synonym: "Sesamia nonagrioides exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:236805 ! has exposure stimulus Sesamia nonagrioides
relationship: RO:0002309 NCBITaxon:236805 ! has exposure stimulus Sesamia nonagrioides

[Term]
id: ECTO:3000287
name: exposure to Oniscidea
def: "A history of exposure to Oniscidea." []
synonym: "Oniscidea exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:41116 ! has exposure stimulus Oniscidea
relationship: RO:0002309 NCBITaxon:41116 ! has exposure stimulus Oniscidea

[Term]
id: ECTO:3000288
name: exposure to Histomonas
def: "A history of exposure to Histomonas." []
synonym: "Histomonas exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:135587 ! has exposure stimulus Histomonas
relationship: RO:0002309 NCBITaxon:135587 ! has exposure stimulus Histomonas

[Term]
id: ECTO:3000289
name: exposure to Human immunodeficiency virus
def: "A history of exposure to Human immunodeficiency virus." []
synonym: "Human immunodeficiency virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12721 ! has exposure stimulus Human immunodeficiency virus
relationship: RO:0002309 NCBITaxon:12721 ! has exposure stimulus Human immunodeficiency virus

[Term]
id: ECTO:3000290
name: exposure to Lagenisma
def: "A history of exposure to Lagenisma." []
synonym: "Lagenisma exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1682048 ! has exposure stimulus Lagenisma
relationship: RO:0002309 NCBITaxon:1682048 ! has exposure stimulus Lagenisma

[Term]
id: ECTO:3000291
name: exposure to Zymoseptoria tritici
def: "A history of exposure to Zymoseptoria tritici." []
synonym: "Zymoseptoria tritici exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1047171 ! has exposure stimulus Zymoseptoria tritici
relationship: RO:0002309 NCBITaxon:1047171 ! has exposure stimulus Zymoseptoria tritici

[Term]
id: ECTO:3000292
name: exposure to Acrocalymma vagum
def: "A history of exposure to Acrocalymma vagum." []
synonym: "Acrocalymma vagum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1589764 ! has exposure stimulus Acrocalymma vagum
relationship: RO:0002309 NCBITaxon:1589764 ! has exposure stimulus Acrocalymma vagum

[Term]
id: ECTO:3000293
name: exposure to Phoma herbarum
def: "A history of exposure to Phoma herbarum." []
synonym: "Phoma herbarum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:73001 ! has exposure stimulus Phoma herbarum
relationship: RO:0002309 NCBITaxon:73001 ! has exposure stimulus Phoma herbarum

[Term]
id: ECTO:3000294
name: exposure to Nigrospora oryzae
def: "A history of exposure to Nigrospora oryzae." []
synonym: "Nigrospora oryzae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:335854 ! has exposure stimulus Nigrospora oryzae
relationship: RO:0002309 NCBITaxon:335854 ! has exposure stimulus Nigrospora oryzae

[Term]
id: ECTO:3000295
name: exposure to Talaromyces verruculosus
def: "A history of exposure to Talaromyces verruculosus." []
synonym: "Talaromyces verruculosus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:198730 ! has exposure stimulus Talaromyces verruculosus
relationship: RO:0002309 NCBITaxon:198730 ! has exposure stimulus Talaromyces verruculosus

[Term]
id: ECTO:3000296
name: exposure to Pseudomonas
def: "A history of exposure to Pseudomonas." []
synonym: "Pseudomonas exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:286 ! has exposure stimulus Pseudomonas
relationship: RO:0002309 NCBITaxon:286 ! has exposure stimulus Pseudomonas

[Term]
id: ECTO:3000297
name: exposure to Laccaria bicolor
def: "A history of exposure to Laccaria bicolor." []
synonym: "Laccaria bicolor exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:29883 ! has exposure stimulus Laccaria bicolor
relationship: RO:0002309 NCBITaxon:29883 ! has exposure stimulus Laccaria bicolor

[Term]
id: ECTO:3000298
name: exposure to Rhizophagus irregularis
def: "A history of exposure to Rhizophagus irregularis." []
synonym: "Rhizophagus irregularis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:588596 ! has exposure stimulus Rhizophagus irregularis
relationship: RO:0002309 NCBITaxon:588596 ! has exposure stimulus Rhizophagus irregularis

[Term]
id: ECTO:3000299
name: exposure to Henosepilachna vigintioctopunctata
def: "A history of exposure to Henosepilachna vigintioctopunctata." []
synonym: "Henosepilachna vigintioctopunctata exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:420089 ! has exposure stimulus Henosepilachna vigintioctopunctata
relationship: RO:0002309 NCBITaxon:420089 ! has exposure stimulus Henosepilachna vigintioctopunctata

[Term]
id: ECTO:3000300
name: exposure to Massilia
def: "A history of exposure to Massilia." []
synonym: "Massilia exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:149698 ! has exposure stimulus Massilia
relationship: RO:0002309 NCBITaxon:149698 ! has exposure stimulus Massilia

[Term]
id: ECTO:3000301
name: exposure to Myxobolus bejeranoi
def: "A history of exposure to Myxobolus bejeranoi." []
synonym: "Myxobolus bejeranoi exposure" EXACT []
is_a: ECTO:3000221 ! exposure to Myxobolus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2015852 ! has exposure stimulus Myxobolus bejeranoi
relationship: RO:0002309 NCBITaxon:2015852 ! has exposure stimulus Myxobolus bejeranoi

[Term]
id: ECTO:3000302
name: exposure to Myxobolus cerebralis
def: "A history of exposure to Myxobolus cerebralis." []
synonym: "Myxobolus cerebralis exposure" EXACT []
is_a: ECTO:3000221 ! exposure to Myxobolus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:59783 ! has exposure stimulus Myxobolus cerebralis
relationship: RO:0002309 NCBITaxon:59783 ! has exposure stimulus Myxobolus cerebralis

[Term]
id: ECTO:3000303
name: exposure to avian paramyxovirus 1
def: "A history of exposure to avian paramyxovirus 1." []
synonym: "avian paramyxovirus 1 exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2560319 ! has exposure stimulus avian paramyxovirus 1
relationship: RO:0002309 NCBITaxon:2560319 ! has exposure stimulus avian paramyxovirus 1

[Term]
id: ECTO:3000304
name: exposure to Papillibacter cinnamivorans
def: "A history of exposure to Papillibacter cinnamivorans." []
synonym: "Papillibacter cinnamivorans exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:100176 ! has exposure stimulus Papillibacter cinnamivorans
relationship: RO:0002309 NCBITaxon:100176 ! has exposure stimulus Papillibacter cinnamivorans

[Term]
id: ECTO:3000305
name: exposure to Oscillibacter ruminantium
def: "A history of exposure to Oscillibacter ruminantium." []
synonym: "Oscillibacter ruminantium exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1263547 ! has exposure stimulus Oscillibacter ruminantium
relationship: RO:0002309 NCBITaxon:1263547 ! has exposure stimulus Oscillibacter ruminantium

[Term]
id: ECTO:3000306
name: exposure to Phytophthora nicotianae
def: "A history of exposure to Phytophthora nicotianae." []
synonym: "Phytophthora nicotianae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:4792 ! has exposure stimulus Phytophthora nicotianae
relationship: RO:0002309 NCBITaxon:4792 ! has exposure stimulus Phytophthora nicotianae

[Term]
id: ECTO:3000307
name: exposure to Potato virus Y
def: "A history of exposure to Potato virus Y." []
synonym: "Potato virus Y exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12216 ! has exposure stimulus Potato virus Y
relationship: RO:0002309 NCBITaxon:12216 ! has exposure stimulus Potato virus Y

[Term]
id: ECTO:3000308
name: exposure to Triops cancriformis
def: "A history of exposure to Triops cancriformis." []
synonym: "Triops cancriformis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:194544 ! has exposure stimulus Triops cancriformis
relationship: RO:0002309 NCBITaxon:194544 ! has exposure stimulus Triops cancriformis

[Term]
id: ECTO:3000309
name: exposure to Ligilactobacillus murinus
def: "A history of exposure to Ligilactobacillus murinus." []
synonym: "Ligilactobacillus murinus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1622 ! has exposure stimulus Ligilactobacillus murinus
relationship: RO:0002309 NCBITaxon:1622 ! has exposure stimulus Ligilactobacillus murinus

[Term]
id: ECTO:3000310
name: exposure to Streptococcus thermophilus
def: "A history of exposure to Streptococcus thermophilus." []
synonym: "Streptococcus thermophilus exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1308 ! has exposure stimulus Streptococcus thermophilus
relationship: RO:0002309 NCBITaxon:1308 ! has exposure stimulus Streptococcus thermophilus

[Term]
id: ECTO:3000311
name: exposure to Bifidobacterium animalis
def: "A history of exposure to Bifidobacterium animalis." []
synonym: "Bifidobacterium animalis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:28025 ! has exposure stimulus Bifidobacterium animalis
relationship: RO:0002309 NCBITaxon:28025 ! has exposure stimulus Bifidobacterium animalis

[Term]
id: ECTO:3000312
name: exposure to Romboutsia hominis
def: "A history of exposure to Romboutsia hominis." []
synonym: "Romboutsia hominis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:1507512 ! has exposure stimulus Romboutsia hominis
relationship: RO:0002309 NCBITaxon:1507512 ! has exposure stimulus Romboutsia hominis

[Term]
id: ECTO:3000313
name: exposure to Trichoderma harzianum
def: "A history of exposure to Trichoderma harzianum." []
synonym: "Trichoderma harzianum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5544 ! has exposure stimulus Trichoderma harzianum
relationship: RO:0002309 NCBITaxon:5544 ! has exposure stimulus Trichoderma harzianum

[Term]
id: ECTO:3000314
name: exposure to Ruminococcus intestinalis
def: "A history of exposure to Ruminococcus intestinalis." []
synonym: "Ruminococcus intestinalis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:2763066 ! has exposure stimulus Ruminococcus intestinalis
relationship: RO:0002309 NCBITaxon:2763066 ! has exposure stimulus Ruminococcus intestinalis

[Term]
id: ECTO:3000315
name: exposure to Sclerotinia sclerotiorum
def: "A history of exposure to Sclerotinia sclerotiorum." []
synonym: "Sclerotinia sclerotiorum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:5180 ! has exposure stimulus Sclerotinia sclerotiorum
relationship: RO:0002309 NCBITaxon:5180 ! has exposure stimulus Sclerotinia sclerotiorum

[Term]
id: ECTO:3000316
name: exposure to Serratia entomophila
def: "A history of exposure to Serratia entomophila." []
synonym: "Serratia entomophila exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:42906 ! has exposure stimulus Serratia entomophila
relationship: RO:0002309 NCBITaxon:42906 ! has exposure stimulus Serratia entomophila

[Term]
id: ECTO:3000317
name: exposure to Deroceras reticulatum
def: "A history of exposure to Deroceras reticulatum." []
synonym: "Deroceras reticulatum exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:145610 ! has exposure stimulus Deroceras reticulatum
relationship: RO:0002309 NCBITaxon:145610 ! has exposure stimulus Deroceras reticulatum

[Term]
id: ECTO:3000318
name: exposure to Tetracapsuloides bryosalmonae
def: "A history of exposure to Tetracapsuloides bryosalmonae." []
synonym: "Tetracapsuloides bryosalmonae exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:271932 ! has exposure stimulus Tetracapsuloides bryosalmonae
relationship: RO:0002309 NCBITaxon:271932 ! has exposure stimulus Tetracapsuloides bryosalmonae

[Term]
id: ECTO:3000319
name: exposure to Tomato mosaic virus
def: "A history of exposure to Tomato mosaic virus." []
synonym: "Tomato mosaic virus exposure" EXACT []
is_a: ECTO:3000001 ! exposure to virus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:12253 ! has exposure stimulus Tomato mosaic virus
relationship: RO:0002309 NCBITaxon:12253 ! has exposure stimulus Tomato mosaic virus

[Term]
id: ECTO:3000320
name: exposure to Trichinella spiralis
def: "A history of exposure to Trichinella spiralis." []
synonym: "Trichinella spiralis exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:6334 ! has exposure stimulus Trichinella spiralis
relationship: RO:0002309 NCBITaxon:6334 ! has exposure stimulus Trichinella spiralis

[Term]
id: ECTO:3000321
name: exposure to Veillonella parvula
def: "A history of exposure to Veillonella parvula." []
synonym: "Veillonella parvula exposure" EXACT []
is_a: ECTO:3000266 ! exposure to Veillonella
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:29466 ! has exposure stimulus Veillonella parvula
relationship: RO:0002309 NCBITaxon:29466 ! has exposure stimulus Veillonella parvula

[Term]
id: ECTO:3000322
name: exposure to Zingiber mioga
def: "A history of exposure to Zingiber mioga." []
synonym: "Zingiber mioga exposure" EXACT []
is_a: ECTO:3000000 ! exposure to organism
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCBITaxon:136225 ! has exposure stimulus Zingiber mioga
relationship: RO:0002309 NCBITaxon:136225 ! has exposure stimulus Zingiber mioga

[Term]
id: ECTO:4000000
name: exposure to change
def: "A exposure event involving the interaction of an exposure receptor to deviation (from_normal) of quality." []
synonym: "exposure to deviation (from_normal) in quality" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000001
name: exposure to increased temperature
def: "A exposure event involving the interaction of an exposure receptor to increased temperature." []
synonym: "increased temperature exposure" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001305 ! has exposure stimulus increased temperature
relationship: RO:0002309 PATO:0001305 ! has exposure stimulus increased temperature

[Term]
id: ECTO:4000002
name: exposure to increased salt
def: "A exposure event involving the interaction of an exposure receptor to increased amount of salt." []
synonym: "exposure to increased amount in salt" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000003
name: exposure to decreased salt
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of salt." []
synonym: "exposure to decreased amount in salt" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000004
name: exposure to increased methane
def: "A exposure event involving the interaction of an exposure receptor to increased amount of methane." []
synonym: "exposure to increased amount in methane" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000005
name: exposure to decreased methane
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of methane." []
synonym: "exposure to decreased amount in methane" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000006
name: exposure to increased glucose
def: "A exposure event involving the interaction of an exposure receptor to increased amount of glucose." []
synonym: "exposure to increased amount in glucose" EXACT []
is_a: ECTO:4000010 ! exposure to increased monosaccharide

[Term]
id: ECTO:4000007
name: exposure to increased fructose
def: "A exposure event involving the interaction of an exposure receptor to increased amount of fructose." []
synonym: "exposure to increased amount in fructose" EXACT []
is_a: ECTO:4000010 ! exposure to increased monosaccharide

[Term]
id: ECTO:4000008
name: exposure to increased sucrose
def: "A exposure event involving the interaction of an exposure receptor to increased amount of sucrose." []
synonym: "exposure to increased amount in sucrose" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000009
name: exposure to increased protein
def: "A exposure event involving the interaction of an exposure receptor to increased amount of protein." []
synonym: "exposure to increased amount in protein" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000010
name: exposure to increased monosaccharide
def: "A exposure event involving the interaction of an exposure receptor to increased amount of monosaccharide." []
synonym: "exposure to increased amount in monosaccharide" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000011
name: exposure to increased cholesterol
def: "A exposure event involving the interaction of an exposure receptor to increased amount of cholesterol." []
synonym: "exposure to increased amount in cholesterol" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000012
name: exposure to increased triglyceride
def: "A exposure event involving the interaction of an exposure receptor to increased amount of triglyceride." []
synonym: "exposure to increased amount in triglyceride" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000013
name: exposure to increased low-density lipoprotein
def: "A exposure event involving the interaction of an exposure receptor to increased amount of low-density lipoprotein." []
synonym: "exposure to increased amount in low-density lipoprotein" EXACT []
is_a: ECTO:4000009 ! exposure to increased protein

[Term]
id: ECTO:4000014
name: exposure to increased high-density lipoprotein
def: "A exposure event involving the interaction of an exposure receptor to increased amount of high-density lipoprotein." []
synonym: "exposure to increased amount in high-density lipoprotein" EXACT []
is_a: ECTO:4000009 ! exposure to increased protein

[Term]
id: ECTO:4000015
name: exposure to decreased glucose
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of glucose." []
synonym: "exposure to decreased amount in glucose" EXACT []
is_a: ECTO:4000019 ! exposure to decreased monosaccharide

[Term]
id: ECTO:4000016
name: exposure to decreased fructose
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of fructose." []
synonym: "exposure to decreased amount in fructose" EXACT []
is_a: ECTO:4000019 ! exposure to decreased monosaccharide

[Term]
id: ECTO:4000017
name: exposure to decreased sucrose
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of sucrose." []
synonym: "exposure to decreased amount in sucrose" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000018
name: exposure to decreased protein
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of protein." []
synonym: "exposure to decreased amount in protein" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000019
name: exposure to decreased monosaccharide
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of monosaccharide." []
synonym: "exposure to decreased amount in monosaccharide" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000020
name: exposure to decreased cholesterol
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of cholesterol." []
synonym: "exposure to decreased amount in cholesterol" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000021
name: exposure to decreased triglyceride
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of triglyceride." []
synonym: "exposure to decreased amount in triglyceride" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000022
name: exposure to decreased low-density lipoprotein
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of low-density lipoprotein." []
synonym: "exposure to decreased amount in low-density lipoprotein" EXACT []
is_a: ECTO:4000018 ! exposure to decreased protein

[Term]
id: ECTO:4000023
name: exposure to decreased high-density lipoprotein
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of high-density lipoprotein." []
synonym: "exposure to decreased amount in high-density lipoprotein" EXACT []
is_a: ECTO:4000018 ! exposure to decreased protein

[Term]
id: ECTO:4000024
name: exposure to increased air pressure
def: "A exposure event involving the interaction of an exposure receptor to increased amount of pressure of air." []
synonym: "exposure to increased amount in pressure of air" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000025
name: exposure to increased pressure
def: "A exposure event involving the interaction of an exposure receptor to increased pressure." []
synonym: "increased pressure exposure" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001576 ! has exposure stimulus increased pressure
relationship: RO:0002309 PATO:0001576 ! has exposure stimulus increased pressure

[Term]
id: ECTO:4000026
name: exposure to decreased pressure
def: "A exposure event involving the interaction of an exposure receptor to decreased pressure." []
synonym: "decreased pressure exposure" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality
is_a: ECTO:0010003 ! exposure to environmental physical object quality
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 PATO:0001575 ! has exposure stimulus decreased pressure
relationship: RO:0002309 PATO:0001575 ! has exposure stimulus decreased pressure

[Term]
id: ECTO:4000027
name: exposure to freezing water
def: "A exposure event involving the interaction of an exposure receptor to frozen of liquid water." []
synonym: "exposure to frozen in liquid water" EXACT []
is_a: ECTO:1000043 ! exposure to temperature of water

[Term]
id: ECTO:4000028
name: exposure to freezing air
def: "A exposure event involving the interaction of an exposure receptor to frozen of air." []
synonym: "exposure to frozen in air" EXACT []
is_a: ECTO:0000980 ! exposure to temperature of air in surroundings

[Term]
id: ECTO:4000029
name: exposure to increased soil temperature
def: "A exposure event involving the interaction of an exposure receptor to increased amount of temperature of soil." []
synonym: "exposure to increased amount in temperature of soil" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000030
name: exposure to decreased soil temperature
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of temperature of soil." []
synonym: "exposure to decreased amount in temperature of soil" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000031
name: exposure to increased water temperature
def: "A exposure event involving the interaction of an exposure receptor to increased amount of temperature of water." []
synonym: "exposure to increased amount in temperature of water" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000032
name: exposure to decreased water temperature
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of temperature of water." []
synonym: "exposure to decreased amount in temperature of water" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000033
name: exposure to decreased water pressure
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of pressure of water." []
synonym: "exposure to decreased amount in pressure of water" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000034
name: exposure to increased air temperature
def: "A exposure event involving the interaction of an exposure receptor to increased amount of temperature of air." []
synonym: "exposure to increased amount in temperature of air" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000035
name: exposure to increased water pressure
def: "A exposure event involving the interaction of an exposure receptor to increased amount of pressure of water." []
synonym: "exposure to increased amount in pressure of water" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000036
name: exposure to decreased air pressure
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of pressure of air." []
synonym: "exposure to decreased amount in pressure of air" EXACT []
is_a: ECTO:4000000 ! exposure to change

[Term]
id: ECTO:4000037
name: exposure to decreased arginine
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of arginine." []
synonym: "exposure to decreased amount in arginine" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000038
name: exposure to decreased leucine
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of leucine." []
synonym: "exposure to decreased amount in leucine" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:4000039
name: exposure to decreased lysine
def: "A exposure event involving the interaction of an exposure receptor to decreased amount of lysine." []
synonym: "exposure to decreased amount in lysine" EXACT []
is_a: ECTO:0010001 ! exposure to qualitative environmental quality

[Term]
id: ECTO:5000000
name: exposure to geographic feature
def: "A exposure event involving the interaction of an exposure receptor to geographic feature." []
synonym: "geographic feature exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00000000 ! has exposure stimulus geographic feature
relationship: RO:0002309 ENVO:00000000 ! has exposure stimulus geographic feature

[Term]
id: ECTO:5000001
name: exposure to sidewalks
def: "A exposure event involving the interaction of an exposure receptor to sidewalk." []
synonym: "sidewalk exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001279 ! has exposure stimulus sidewalk
relationship: RO:0002309 ENVO:01001279 ! has exposure stimulus sidewalk

[Term]
id: ECTO:5000002
name: exposure to public swimming pool
def: "A exposure event involving the interaction of an exposure receptor to public swimming pool." []
synonym: "public swimming pool exposure" EXACT []
is_a: ECTO:1000021 ! exposure to construction
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000967 ! has exposure stimulus public swimming pool
relationship: RO:0002309 ENVO:01000967 ! has exposure stimulus public swimming pool

[Term]
id: ECTO:5000003
name: exposure to mine drainage
def: "A exposure event involving the interaction of an exposure receptor to mine drainage." []
synonym: "mine drainage exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00001996 ! has exposure stimulus mine drainage
relationship: RO:0002309 ENVO:00001996 ! has exposure stimulus mine drainage

[Term]
id: ECTO:5000004
name: exposure to acid mine drainage
def: "A exposure event involving the interaction of an exposure receptor to acid mine drainage." []
synonym: "acid mine drainage exposure" EXACT []
is_a: ECTO:5000003 ! exposure to mine drainage
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00001997 ! has exposure stimulus acid mine drainage
relationship: RO:0002309 ENVO:00001997 ! has exposure stimulus acid mine drainage

[Term]
id: ECTO:5000005
name: exposure to gold mine drainage
def: "A exposure event involving the interaction of an exposure receptor to gold mine drainage." []
synonym: "gold mine drainage exposure" EXACT []
is_a: ECTO:5000003 ! exposure to mine drainage
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002112 ! has exposure stimulus gold mine drainage
relationship: RO:0002309 ENVO:00002112 ! has exposure stimulus gold mine drainage

[Term]
id: ECTO:5000006
name: exposure to gold mine
def: "A exposure event involving the interaction of an exposure receptor to gold mine." []
synonym: "gold mine exposure" EXACT []
is_a: ECTO:1000003 ! exposure to mine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002168 ! has exposure stimulus gold mine
relationship: RO:0002309 ENVO:00002168 ! has exposure stimulus gold mine

[Term]
id: ECTO:5000007
name: exposure to coal mine
def: "A exposure event involving the interaction of an exposure receptor to coal mine." []
synonym: "coal mine exposure" EXACT []
is_a: ECTO:1000003 ! exposure to mine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002169 ! has exposure stimulus coal mine
relationship: RO:0002309 ENVO:00002169 ! has exposure stimulus coal mine

[Term]
id: ECTO:5000008
name: exposure to petting zoo
def: "A exposure event involving the interaction of an exposure receptor to petting zoo." []
synonym: "petting zoo exposure" EXACT []
is_a: ECTO:5000000 ! exposure to geographic feature
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000923 ! has exposure stimulus petting zoo
relationship: RO:0002309 ENVO:01000923 ! has exposure stimulus petting zoo

[Term]
id: ECTO:5000009
name: exposure to campground
def: "A exposure event involving the interaction of an exposure receptor to campground." []
synonym: "campground exposure" EXACT []
is_a: ECTO:5000000 ! exposure to geographic feature
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000935 ! has exposure stimulus campground
relationship: RO:0002309 ENVO:01000935 ! has exposure stimulus campground

[Term]
id: ECTO:6000000
name: exposure to behavior
def: "An exposure event involving Activity" []
synonym: "Activity exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C43431 ! has exposure stimulus Activity
relationship: RO:0002309 NCIT:C43431 ! has exposure stimulus Activity

[Term]
id: ECTO:6000001
name: exposure to violence
def: "An exposure event involving Violence" []
synonym: "Violence exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C93214 ! has exposure stimulus Violence
relationship: RO:0002309 NCIT:C93214 ! has exposure stimulus Violence

[Term]
id: ECTO:6000002
name: exposure to exercise
def: "An exposure event involving Exercise" []
synonym: "Exercise exposure" EXACT []
is_a: ECTO:6000039 ! exposure to Physical Activity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C16567 ! has exposure stimulus Exercise
relationship: RO:0002309 NCIT:C16567 ! has exposure stimulus Exercise

[Term]
id: ECTO:6000003
name: exposure to walking
def: "An exposure event involving Walking" []
synonym: "Walking exposure" EXACT []
is_a: ECTO:6000039 ! exposure to Physical Activity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C73554 ! has exposure stimulus Walking
relationship: RO:0002309 NCIT:C73554 ! has exposure stimulus Walking

[Term]
id: ECTO:6000004
name: exposure to sedentary lifestyle
def: "An exposure event involving Sedentary Lifestyle" []
synonym: "Sedentary Lifestyle exposure" EXACT []
is_a: ECTO:6000015 ! exposure to lifestyle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C86589 ! has exposure stimulus Sedentary Lifestyle
relationship: RO:0002309 NCIT:C86589 ! has exposure stimulus Sedentary Lifestyle

[Term]
id: ECTO:6000005
name: exposure to coping skills
def: "An exposure event involving Coping Skills" []
synonym: "Coping Skills exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C19382 ! has exposure stimulus Coping Skills
relationship: RO:0002309 NCIT:C19382 ! has exposure stimulus Coping Skills

[Term]
id: ECTO:6000006
name: exposure to sex behavior
def: "An exposure event involving Sex Behavior" []
synonym: "Sex Behavior exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17127 ! has exposure stimulus Sex Behavior
relationship: RO:0002309 NCIT:C17127 ! has exposure stimulus Sex Behavior

[Term]
id: ECTO:6000007
name: exposure to substance abuse
def: "An exposure event involving Substance Abuse" []
synonym: "Substance Abuse exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C18272 ! has exposure stimulus Substance Abuse
relationship: RO:0002309 NCIT:C18272 ! has exposure stimulus Substance Abuse

[Term]
id: ECTO:6000008
name: exposure to drug abuse
def: "An exposure event involving Drug Abuse" []
synonym: "Drug Abuse exposure" EXACT []
is_a: ECTO:6000007 ! exposure to substance abuse
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C16522 ! has exposure stimulus Drug Abuse
relationship: RO:0002309 NCIT:C16522 ! has exposure stimulus Drug Abuse

[Term]
id: ECTO:6000009
name: exposure to alcohol abuse
def: "An exposure event involving Alcohol Abuse" []
synonym: "Alcohol Abuse exposure" EXACT []
is_a: ECTO:6000007 ! exposure to substance abuse
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C20701 ! has exposure stimulus Alcohol Abuse
relationship: RO:0002309 NCIT:C20701 ! has exposure stimulus Alcohol Abuse

[Term]
id: ECTO:6000010
name: exposure to social networking
def: "An exposure event involving Social Networking" []
synonym: "Social Networking exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C19035 ! has exposure stimulus Social Networking
relationship: RO:0002309 NCIT:C19035 ! has exposure stimulus Social Networking

[Term]
id: ECTO:6000011
name: exposure to risk reduction
def: "An exposure event involving Risk Reduction" []
synonym: "Risk Reduction exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C19694 ! has exposure stimulus Risk Reduction
relationship: RO:0002309 NCIT:C19694 ! has exposure stimulus Risk Reduction

[Term]
id: ECTO:6000012
name: exposure to flame-broiling
def: "An exposure event involving Flame-Broiling" []
synonym: "Flame-Broiling exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C20026 ! has exposure stimulus Flame-Broiling
relationship: RO:0002309 NCIT:C20026 ! has exposure stimulus Flame-Broiling

[Term]
id: ECTO:6000013
name: exposure to smoking
def: "An exposure event involving Smoking" []
synonym: "Smoking exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C154329 ! has exposure stimulus Smoking
relationship: RO:0002309 NCIT:C154329 ! has exposure stimulus Smoking

[Term]
id: ECTO:6000014
name: exposure to smoking cessation
def: "An exposure event involving Smoking Cessation" []
synonym: "Smoking Cessation exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17427 ! has exposure stimulus Smoking Cessation
relationship: RO:0002309 NCIT:C17427 ! has exposure stimulus Smoking Cessation

[Term]
id: ECTO:6000015
name: exposure to lifestyle
def: "An exposure event involving Lifestyle" []
synonym: "Lifestyle exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C16795 ! has exposure stimulus Lifestyle
relationship: RO:0002309 NCIT:C16795 ! has exposure stimulus Lifestyle

[Term]
id: ECTO:6000016
name: exposure to personal behavior
def: "An exposure event involving Personal Behavior" []
synonym: "Personal Behavior exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C19683 ! has exposure stimulus Personal Behavior
relationship: RO:0002309 NCIT:C19683 ! has exposure stimulus Personal Behavior

[Term]
id: ECTO:6000017
name: obsolete exposure to dietary practices
is_obsolete: true

[Term]
id: ECTO:6000018
name: obsolete exposure to red meat consumption
is_obsolete: true
replaced_by: ECTO:0700003

[Term]
id: ECTO:6000019
name: obsolete exposure to high vegetable diet
is_obsolete: true
replaced_by: ECTO:0030001

[Term]
id: ECTO:6000020
name: obsolete exposure to feeding regimen
is_obsolete: true

[Term]
id: ECTO:6000021
name: exposure to eating behavior
def: "An exposure event involving Dietary Practices" []
synonym: "Dietary Practices exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C19706 ! has exposure stimulus Dietary Practices
relationship: RO:0002309 NCIT:C19706 ! has exposure stimulus Dietary Practices

[Term]
id: ECTO:6000022
name: exposure to drinking behavior
def: "An exposure event involving drinking behavior" []
synonym: "drinking behavior exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 GO:0042756 ! has exposure stimulus drinking behavior
relationship: RO:0002309 GO:0042756 ! has exposure stimulus drinking behavior

[Term]
id: ECTO:6000023
name: exposure to food processing behavior
def: "An exposure event involving Food Preparation" []
synonym: "Food Preparation exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17604 ! has exposure stimulus Food Preparation
relationship: RO:0002309 NCIT:C17604 ! has exposure stimulus Food Preparation

[Term]
id: ECTO:6000024
name: exposure to clinical or research activity
def: "An exposure event involving Clinical or Research Activity" []
synonym: "Clinical or Research Activity exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C16203 ! has exposure stimulus Clinical or Research Activity
relationship: RO:0002309 NCIT:C16203 ! has exposure stimulus Clinical or Research Activity

[Term]
id: ECTO:6000025
name: exposure to unemployment
def: "An exposure event involving Unemployed" []
synonym: "Unemployed exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C75563 ! has exposure stimulus Unemployed
relationship: RO:0002309 NCIT:C75563 ! has exposure stimulus Unemployed

[Term]
id: ECTO:6000026
name: exposure to poverty
def: "An exposure event involving Poverty" []
synonym: "Poverty exposure" EXACT []
is_a: ECTO:6000028 ! exposure to socioeconomic factors
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17009 ! has exposure stimulus Poverty
relationship: RO:0002309 NCIT:C17009 ! has exposure stimulus Poverty

[Term]
id: ECTO:6000027
name: exposure to social circumstances
def: "An exposure event involving Social Circumstances" []
synonym: "Social Circumstances exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C20188 ! has exposure stimulus Social Circumstances
relationship: RO:0002309 NCIT:C20188 ! has exposure stimulus Social Circumstances

[Term]
id: ECTO:6000028
name: exposure to socioeconomic factors
def: "An exposure event involving Socioeconomic Factors" []
synonym: "Socioeconomic Factors exposure" EXACT []
is_a: ECTO:6000027 ! exposure to social circumstances
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17468 ! has exposure stimulus Socioeconomic Factors
relationship: RO:0002309 NCIT:C17468 ! has exposure stimulus Socioeconomic Factors

[Term]
id: ECTO:6000029
name: exposure to tobacco smoking
def: "An exposure event involving Tobacco Smoking" []
synonym: "Tobacco Smoking exposure" EXACT []
is_a: ECTO:6000013 ! exposure to smoking
is_a: ECTO:6000041 ! exposure to Tobacco Use
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17934 ! has exposure stimulus Tobacco Smoking
relationship: RO:0002309 NCIT:C17934 ! has exposure stimulus Tobacco Smoking

[Term]
id: ECTO:6000030
name: exposure to hunting
def: "An exposure event involving hunting behavior" []
synonym: "hunting behavior exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NBO:0009003 ! has exposure stimulus hunting behavior
relationship: RO:0002309 NBO:0009003 ! has exposure stimulus hunting behavior

[Term]
id: ECTO:6000031
name: exposure to strenuous exercise
def: "An exposure event involving Strenuous Exercise" []
synonym: "Strenuous Exercise exposure" EXACT []
is_a: ECTO:6000002 ! exposure to exercise
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C39773 ! has exposure stimulus Strenuous Exercise
relationship: RO:0002309 NCIT:C39773 ! has exposure stimulus Strenuous Exercise

[Term]
id: ECTO:6000032
name: exposure to weight bearing
def: "An exposure event involving Weight Bearing" []
synonym: "Weight Bearing exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C178214 ! has exposure stimulus Weight Bearing
relationship: RO:0002309 NCIT:C178214 ! has exposure stimulus Weight Bearing

[Term]
id: ECTO:6000033
name: exposure to travel
def: "An exposure event involving Travel" []
synonym: "Travel exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C53462 ! has exposure stimulus Travel
relationship: RO:0002309 NCIT:C53462 ! has exposure stimulus Travel

[Term]
id: ECTO:6000035
name: exposure to isometric exercise
def: "An exposure event involving Isometric Exercise" []
synonym: "Isometric Exercise exposure" EXACT []
is_a: ECTO:6000002 ! exposure to exercise
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C21057 ! has exposure stimulus Isometric Exercise
relationship: RO:0002309 NCIT:C21057 ! has exposure stimulus Isometric Exercise

[Term]
id: ECTO:6000036
name: exposure to moderate exercise
def: "An exposure event involving Moderate Exercise" []
synonym: "Moderate Exercise exposure" EXACT []
is_a: ECTO:6000002 ! exposure to exercise
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C39772 ! has exposure stimulus Moderate Exercise
relationship: RO:0002309 NCIT:C39772 ! has exposure stimulus Moderate Exercise

[Term]
id: ECTO:6000037
name: exposure to High-Intensity Interval Training
def: "An exposure event involving High-Intensity Interval Training" []
synonym: "High-Intensity Interval Training exposure" EXACT []
is_a: ECTO:6000031 ! exposure to strenuous exercise
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C185297 ! has exposure stimulus High-Intensity Interval Training
relationship: RO:0002309 NCIT:C185297 ! has exposure stimulus High-Intensity Interval Training

[Term]
id: ECTO:6000038
name: exposure to Cigarette Smoking
def: "An exposure event involving Cigarette Smoking" []
synonym: "Cigarette Smoking exposure" EXACT []
is_a: ECTO:6000029 ! exposure to tobacco smoking
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C18270 ! has exposure stimulus Cigarette Smoking
relationship: RO:0002309 NCIT:C18270 ! has exposure stimulus Cigarette Smoking

[Term]
id: ECTO:6000039
name: exposure to Physical Activity
def: "An exposure event involving Physical Activity" []
synonym: "Physical Activity exposure" EXACT []
is_a: ECTO:6000000 ! exposure to behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C17708 ! has exposure stimulus Physical Activity
relationship: RO:0002309 NCIT:C17708 ! has exposure stimulus Physical Activity

[Term]
id: ECTO:6000040
name: exposure to Resistance Training
def: "An exposure event involving Resistance Training" []
synonym: "Resistance Training exposure" EXACT []
is_a: ECTO:6000039 ! exposure to Physical Activity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C154219 ! has exposure stimulus Resistance Training
relationship: RO:0002309 NCIT:C154219 ! has exposure stimulus Resistance Training

[Term]
id: ECTO:6000041
name: exposure to Tobacco Use
def: "An exposure event involving Tobacco Use" []
synonym: "Tobacco Use exposure" EXACT []
is_a: ECTO:6000016 ! exposure to personal behavior
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 NCIT:C18059 ! has exposure stimulus Tobacco Use
relationship: RO:0002309 NCIT:C18059 ! has exposure stimulus Tobacco Use

[Term]
id: ECTO:7000001
name: exposure to dust
def: "A exposure event involving the interaction of an exposure receptor to dust." []
synonym: "dust exposure" EXACT []
is_a: ECTO:7000068 ! exposure to particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002008 ! has exposure stimulus dust
relationship: RO:0002309 ENVO:00002008 ! has exposure stimulus dust

[Term]
id: ECTO:7000002
name: exposure to fumes
def: "A exposure event involving the interaction of an exposure receptor to fume." []
synonym: "fume exposure" EXACT []
is_a: ECTO:7000058 ! exposure to gaseous environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000112 ! has exposure stimulus fume
relationship: RO:0002309 ENVO:02000112 ! has exposure stimulus fume

[Term]
id: ECTO:7000003
name: exposure to smog
def: "A exposure event involving the interaction of an exposure receptor to smog." []
synonym: "smog exposure" EXACT []
is_a: ECTO:7000114 ! exposure to aerosol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000842 ! has exposure stimulus smog
relationship: RO:0002309 ENVO:01000842 ! has exposure stimulus smog

[Term]
id: ECTO:7000004
name: exposure to coal
def: "A exposure event involving the interaction of an exposure receptor to coal." []
synonym: "coal exposure" EXACT []
is_a: ECTO:7000018 ! exposure to rock
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000091 ! has exposure stimulus coal
relationship: RO:0002309 ENVO:02000091 ! has exposure stimulus coal

[Term]
id: ECTO:7000005
name: exposure to coal dust
def: "A exposure event involving the interaction of an exposure receptor to coal dust." []
synonym: "coal dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000099 ! has exposure stimulus coal dust
relationship: RO:0002309 ENVO:02000099 ! has exposure stimulus coal dust

[Term]
id: ECTO:7000006
name: exposure to coal mine waste material
def: "A exposure event involving the interaction of an exposure receptor to coal mine waste material." []
synonym: "coal mine waste material exposure" EXACT []
is_a: ECTO:7000094 ! exposure to industrial waste material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002206 ! has exposure stimulus coal mine waste material
relationship: RO:0002309 ENVO:00002206 ! has exposure stimulus coal mine waste material

[Term]
id: ECTO:7000007
name: exposure to self-heating coal mine waste material
def: "A exposure event involving the interaction of an exposure receptor to self-heating coal mine waste material." []
synonym: "self-heating coal mine waste material exposure" EXACT []
is_a: ECTO:7000006 ! exposure to coal mine waste material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002207 ! has exposure stimulus self-heating coal mine waste material
relationship: RO:0002309 ENVO:00002207 ! has exposure stimulus self-heating coal mine waste material

[Term]
id: ECTO:7000008
name: exposure to clay
def: "A exposure event involving the interaction of an exposure receptor to clay." []
synonym: "clay exposure" EXACT []
is_a: ECTO:7000068 ! exposure to particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002982 ! has exposure stimulus clay
relationship: RO:0002309 ENVO:00002982 ! has exposure stimulus clay

[Term]
id: ECTO:7000009
name: exposure to clay dust
def: "A exposure event involving the interaction of an exposure receptor to clay dust." []
synonym: "clay dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000105 ! has exposure stimulus clay dust
relationship: RO:0002309 ENVO:02000105 ! has exposure stimulus clay dust

[Term]
id: ECTO:7000010
name: exposure to brick
def: "A exposure event involving the interaction of an exposure receptor to brick." []
synonym: "brick exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000475 ! has exposure stimulus brick
relationship: RO:0002309 ENVO:01000475 ! has exposure stimulus brick

[Term]
id: ECTO:7000011
name: exposure to brick material
def: "A exposure event involving the interaction of an exposure receptor to brick material." []
synonym: "brick material exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000474 ! has exposure stimulus brick material
relationship: RO:0002309 ENVO:01000474 ! has exposure stimulus brick material

[Term]
id: ECTO:7000012
name: exposure to soil
def: "A exposure event involving the interaction of an exposure receptor to soil." []
synonym: "soil exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00001998 ! has exposure stimulus soil
relationship: RO:0002309 ENVO:00001998 ! has exposure stimulus soil

[Term]
id: ECTO:7000013
name: exposure to asphalt
def: "A exposure event involving the interaction of an exposure receptor to asphalt." []
synonym: "asphalt exposure" EXACT []
is_a: ECTO:7000105 ! exposure to petroleum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000460 ! has exposure stimulus asphalt
relationship: RO:0002309 ENVO:01000460 ! has exposure stimulus asphalt

[Term]
id: ECTO:7000014
name: exposure to refined asphalt
def: "A exposure event involving the interaction of an exposure receptor to refined asphalt." []
synonym: "refined asphalt exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000461 ! has exposure stimulus refined asphalt
relationship: RO:0002309 ENVO:01000461 ! has exposure stimulus refined asphalt

[Term]
id: ECTO:7000015
name: exposure to asphalt concrete
def: "A exposure event involving the interaction of an exposure receptor to asphalt concrete." []
synonym: "asphalt concrete exposure" EXACT []
is_a: ECTO:7000037 ! exposure to concrete
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000459 ! has exposure stimulus asphalt concrete
relationship: RO:0002309 ENVO:01000459 ! has exposure stimulus asphalt concrete

[Term]
id: ECTO:7000016
name: exposure to glass
def: "A exposure event involving the interaction of an exposure receptor to glass." []
synonym: "glass exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000480 ! has exposure stimulus glass
relationship: RO:0002309 ENVO:01000480 ! has exposure stimulus glass

[Term]
id: ECTO:7000017
name: exposure to fibrous glass dust
def: "A exposure event involving the interaction of an exposure receptor to fibrous glass dust." []
synonym: "fibrous glass dust exposure" EXACT []
is_a: ECTO:7000022 ! exposure to fibrous dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000102 ! has exposure stimulus fibrous glass dust
relationship: RO:0002309 ENVO:02000102 ! has exposure stimulus fibrous glass dust

[Term]
id: ECTO:7000018
name: exposure to rock
def: "A exposure event involving the interaction of an exposure receptor to rock." []
synonym: "rock exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00001995 ! has exposure stimulus rock
relationship: RO:0002309 ENVO:00001995 ! has exposure stimulus rock

[Term]
id: ECTO:7000019
name: exposure to ore
def: "A exposure event involving the interaction of an exposure receptor to ore." []
synonym: "ore exposure" EXACT []
is_a: ECTO:7000018 ! exposure to rock
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000094 ! has exposure stimulus ore
relationship: RO:0002309 ENVO:02000094 ! has exposure stimulus ore

[Term]
id: ECTO:7000020
name: exposure to sand
def: "A exposure event involving the interaction of an exposure receptor to sand." []
synonym: "sand exposure" EXACT []
is_a: ECTO:7000068 ! exposure to particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000017 ! has exposure stimulus sand
relationship: RO:0002309 ENVO:01000017 ! has exposure stimulus sand

[Term]
id: ECTO:7000021
name: exposure to metallic dust
def: "A exposure event involving the interaction of an exposure receptor to metallic dust." []
synonym: "metallic dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000103 ! has exposure stimulus metallic dust
relationship: RO:0002309 ENVO:02000103 ! has exposure stimulus metallic dust

[Term]
id: ECTO:7000022
name: exposure to fibrous dust
def: "A exposure event involving the interaction of an exposure receptor to fibrous dust." []
synonym: "fibrous dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000101 ! has exposure stimulus fibrous dust
relationship: RO:0002309 ENVO:02000101 ! has exposure stimulus fibrous dust

[Term]
id: ECTO:7000023
name: exposure to mineral dust
def: "A exposure event involving the interaction of an exposure receptor to mineral dust." []
synonym: "mineral dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
is_a: ECTO:7000073 ! exposure to mineral material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000100 ! has exposure stimulus mineral dust
relationship: RO:0002309 ENVO:02000100 ! has exposure stimulus mineral dust

[Term]
id: ECTO:7000024
name: exposure to grain dust
def: "A exposure event involving the interaction of an exposure receptor to grain dust." []
synonym: "grain dust exposure" EXACT []
is_a: ECTO:7000033 ! exposure to dust from plant parts
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000107 ! has exposure stimulus grain dust
relationship: RO:0002309 ENVO:02000107 ! has exposure stimulus grain dust

[Term]
id: ECTO:7000025
name: exposure to asbestos dust
def: "A exposure event involving the interaction of an exposure receptor to asbestos dust." []
synonym: "asbestos dust exposure" EXACT []
is_a: ECTO:7000022 ! exposure to fibrous dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000106 ! has exposure stimulus asbestos dust
relationship: RO:0002309 ENVO:02000106 ! has exposure stimulus asbestos dust

[Term]
id: ECTO:7000026
name: exposure to cement dust
def: "A exposure event involving the interaction of an exposure receptor to cement dust." []
synonym: "cement dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000104 ! has exposure stimulus cement dust
relationship: RO:0002309 ENVO:02000104 ! has exposure stimulus cement dust

[Term]
id: ECTO:7000027
name: exposure to slate dust
def: "A exposure event involving the interaction of an exposure receptor to slate dust." []
synonym: "slate dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001286 ! has exposure stimulus slate dust
relationship: RO:0002309 ENVO:01001286 ! has exposure stimulus slate dust

[Term]
id: ECTO:7000028
name: exposure to talc dust
def: "A exposure event involving the interaction of an exposure receptor to talc dust." []
synonym: "talc dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001285 ! has exposure stimulus talc dust
relationship: RO:0002309 ENVO:01001285 ! has exposure stimulus talc dust

[Term]
id: ECTO:7000029
name: exposure to kaolin dust
def: "A exposure event involving the interaction of an exposure receptor to kaolin dust." []
synonym: "kaolin dust exposure" EXACT []
is_a: ECTO:7000023 ! exposure to mineral dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001288 ! has exposure stimulus kaolin dust
relationship: RO:0002309 ENVO:01001288 ! has exposure stimulus kaolin dust

[Term]
id: ECTO:7000030
name: exposure to silica dust
def: "A exposure event involving the interaction of an exposure receptor to silica dust." []
synonym: "silica dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001282 ! has exposure stimulus silica dust
relationship: RO:0002309 ENVO:01001282 ! has exposure stimulus silica dust

[Term]
id: ECTO:7000031
name: exposure to barium dust
def: "A exposure event involving the interaction of an exposure receptor to barium dust." []
synonym: "barium dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001284 ! has exposure stimulus barium dust
relationship: RO:0002309 ENVO:01001284 ! has exposure stimulus barium dust

[Term]
id: ECTO:7000032
name: exposure to aluminum dust
def: "A exposure event involving the interaction of an exposure receptor to aluminium dust." []
synonym: "aluminium dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001283 ! has exposure stimulus aluminium dust
relationship: RO:0002309 ENVO:01001283 ! has exposure stimulus aluminium dust

[Term]
id: ECTO:7000033
name: exposure to dust from plant parts
def: "A exposure event involving the interaction of an exposure receptor to dust from plant parts." []
synonym: "dust from plant parts exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000109 ! has exposure stimulus dust from plant parts
relationship: RO:0002309 ENVO:02000109 ! has exposure stimulus dust from plant parts

[Term]
id: ECTO:7000034
name: exposure to wood
def: "A exposure event involving the interaction of an exposure receptor to wood." []
synonym: "wood exposure" EXACT []
is_a: ECTO:7000069 ! exposure to organic material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002040 ! has exposure stimulus wood
relationship: RO:0002309 ENVO:00002040 ! has exposure stimulus wood

[Term]
id: ECTO:7000035
name: exposure to treated wood
def: "A exposure event involving the interaction of an exposure receptor to treated wood." []
synonym: "treated wood exposure" EXACT []
is_a: ECTO:7000034 ! exposure to wood
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002135 ! has exposure stimulus treated wood
relationship: RO:0002309 ENVO:00002135 ! has exposure stimulus treated wood

[Term]
id: ECTO:7000036
name: exposure to charcoal
def: "A exposure event involving the interaction of an exposure receptor to charcoal." []
synonym: "charcoal exposure" EXACT []
is_a: ECTO:7000069 ! exposure to organic material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000560 ! has exposure stimulus charcoal
relationship: RO:0002309 ENVO:01000560 ! has exposure stimulus charcoal

[Term]
id: ECTO:7000037
name: exposure to concrete
def: "A exposure event involving the interaction of an exposure receptor to concrete." []
synonym: "concrete exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000458 ! has exposure stimulus concrete
relationship: RO:0002309 ENVO:01000458 ! has exposure stimulus concrete

[Term]
id: ECTO:7000038
name: exposure to plaster
def: "A exposure event involving the interaction of an exposure receptor to plaster." []
synonym: "plaster exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000476 ! has exposure stimulus plaster
relationship: RO:0002309 ENVO:01000476 ! has exposure stimulus plaster

[Term]
id: ECTO:7000039
name: exposure to cement plaster
def: "A exposure event involving the interaction of an exposure receptor to cement plaster." []
synonym: "cement plaster exposure" EXACT []
is_a: ECTO:7000038 ! exposure to plaster
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000478 ! has exposure stimulus cement plaster
relationship: RO:0002309 ENVO:01000478 ! has exposure stimulus cement plaster

[Term]
id: ECTO:7000040
name: exposure to lime plaster
def: "A exposure event involving the interaction of an exposure receptor to lime plaster." []
synonym: "lime plaster exposure" EXACT []
is_a: ECTO:7000038 ! exposure to plaster
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000479 ! has exposure stimulus lime plaster
relationship: RO:0002309 ENVO:01000479 ! has exposure stimulus lime plaster

[Term]
id: ECTO:7000042
name: exposure to particle radiation
def: "A exposure event involving the interaction of an exposure receptor to particle radiation." []
synonym: "particle radiation exposure" EXACT []
is_a: ECTO:0000001 ! exposure to radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001024 ! has exposure stimulus particle radiation
relationship: RO:0002309 ENVO:01001024 ! has exposure stimulus particle radiation

[Term]
id: ECTO:7000045
name: exposure to stellar radiation
def: "A exposure event involving the interaction of an exposure receptor to stellar radiation." []
synonym: "stellar radiation exposure" EXACT []
is_a: ECTO:0000002 ! exposure to electromagnetic radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001211 ! has exposure stimulus stellar radiation
relationship: RO:0002309 ENVO:01001211 ! has exposure stimulus stellar radiation

[Term]
id: ECTO:7000047
name: exposure to ionizing radiation
def: "A exposure event involving the interaction of an exposure receptor to ionizing radiation." []
synonym: "ionizing radiation exposure" EXACT []
is_a: ECTO:0000002 ! exposure to electromagnetic radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001219 ! has exposure stimulus ionizing radiation
relationship: RO:0002309 ENVO:21001219 ! has exposure stimulus ionizing radiation

[Term]
id: ECTO:7000050
name: exposure to particle beam radiation
def: "A exposure event involving the interaction of an exposure receptor to particle beam radiation." []
synonym: "particle beam radiation exposure" EXACT []
is_a: ECTO:7000042 ! exposure to particle radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001025 ! has exposure stimulus particle beam radiation
relationship: RO:0002309 ENVO:01001025 ! has exposure stimulus particle beam radiation

[Term]
id: ECTO:7000053
name: obsolete exposure to X-ray radiation
is_obsolete: true
replaced_by: ECTO:8000046

[Term]
id: ECTO:7000055
name: exposure to liquefied natural gas
def: "A exposure event involving the interaction of an exposure receptor to liquefied natural gas." []
synonym: "liquefied natural gas exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000557 ! has exposure stimulus liquefied natural gas
relationship: RO:0002309 ENVO:01000557 ! has exposure stimulus liquefied natural gas

[Term]
id: ECTO:7000056
name: exposure to natural gas
def: "A exposure event involving the interaction of an exposure receptor to natural gas." []
synonym: "natural gas exposure" EXACT []
is_a: ECTO:7000058 ! exposure to gaseous environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000552 ! has exposure stimulus natural gas
relationship: RO:0002309 ENVO:01000552 ! has exposure stimulus natural gas

[Term]
id: ECTO:7000057
name: exposure to liquefied petroleum gas
def: "A exposure event involving the interaction of an exposure receptor to liquefied petroleum gas." []
synonym: "liquefied petroleum gas exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000553 ! has exposure stimulus liquefied petroleum gas
relationship: RO:0002309 ENVO:01000553 ! has exposure stimulus liquefied petroleum gas

[Term]
id: ECTO:7000058
name: exposure to gaseous environmental material
def: "A exposure event involving the interaction of an exposure receptor to gaseous environmental material." []
synonym: "gaseous environmental material exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000797 ! has exposure stimulus gaseous environmental material
relationship: RO:0002309 ENVO:01000797 ! has exposure stimulus gaseous environmental material

[Term]
id: ECTO:7000059
name: exposure to smoke
def: "A exposure event involving the interaction of an exposure receptor to smoke." []
synonym: "smoke exposure" EXACT []
is_a: ECTO:7000114 ! exposure to aerosol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000838 ! has exposure stimulus smoke
relationship: RO:0002309 ENVO:01000838 ! has exposure stimulus smoke

[Term]
id: ECTO:7000060
name: exposure to haze
def: "A exposure event involving the interaction of an exposure receptor to haze." []
synonym: "haze exposure" EXACT []
is_a: ECTO:7000114 ! exposure to aerosol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001402 ! has exposure stimulus haze
relationship: RO:0002309 ENVO:01001402 ! has exposure stimulus haze

[Term]
id: ECTO:7000061
name: exposure to microplastic particle
def: "A exposure event involving the interaction of an exposure receptor to microplastic particle." []
synonym: "microplastic particle exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000944 ! has exposure stimulus microplastic particle
relationship: RO:0002309 ENVO:01000944 ! has exposure stimulus microplastic particle

[Term]
id: ECTO:7000062
name: exposure to secondary microplastic particle
def: "A exposure event involving the interaction of an exposure receptor to secondary microplastic particle." []
synonym: "secondary microplastic particle exposure" EXACT []
is_a: ECTO:7000061 ! exposure to microplastic particle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000946 ! has exposure stimulus secondary microplastic particle
relationship: RO:0002309 ENVO:01000946 ! has exposure stimulus secondary microplastic particle

[Term]
id: ECTO:7000063
name: exposure to water in environment
def: "A exposure event involving the interaction of an exposure receptor to liquid water." []
synonym: "liquid water exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002006 ! has exposure stimulus liquid water
relationship: RO:0002309 ENVO:00002006 ! has exposure stimulus liquid water

[Term]
id: ECTO:7000064
name: exposure to air
def: "A exposure event involving the interaction of an exposure receptor to air." []
synonym: "air exposure" EXACT []
is_a: ECTO:7000058 ! exposure to gaseous environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002005 ! has exposure stimulus air
relationship: RO:0002309 ENVO:00002005 ! has exposure stimulus air

[Term]
id: ECTO:7000067
name: exposure to oil
def: "A exposure event involving the interaction of an exposure receptor to oil." []
synonym: "oil exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002985 ! has exposure stimulus oil
relationship: RO:0002309 ENVO:00002985 ! has exposure stimulus oil

[Term]
id: ECTO:7000068
name: exposure to particulate matter
def: "A exposure event involving the interaction of an exposure receptor to particulate environmental material." []
synonym: "particulate environmental material exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000060 ! has exposure stimulus particulate environmental material
relationship: RO:0002309 ENVO:01000060 ! has exposure stimulus particulate environmental material

[Term]
id: ECTO:7000069
name: exposure to organic material
def: "A exposure event involving the interaction of an exposure receptor to organic material." []
synonym: "organic material exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000155 ! has exposure stimulus organic material
relationship: RO:0002309 ENVO:01000155 ! has exposure stimulus organic material

[Term]
id: ECTO:7000070
name: exposure to snow
def: "A exposure event involving the interaction of an exposure receptor to snow." []
synonym: "snow exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000406 ! has exposure stimulus snow
relationship: RO:0002309 ENVO:01000406 ! has exposure stimulus snow

[Term]
id: ECTO:7000071
name: exposure to atmospheric carbon dioxide
def: "A exposure event involving the interaction of an exposure receptor to atmospheric carbon dioxide." []
synonym: "atmospheric carbon dioxide exposure" EXACT []
is_a: ECTO:7000058 ! exposure to gaseous environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000451 ! has exposure stimulus atmospheric carbon dioxide
relationship: RO:0002309 ENVO:01000451 ! has exposure stimulus atmospheric carbon dioxide

[Term]
id: ECTO:7000072
name: exposure to volcanic ash
def: "A exposure event involving the interaction of an exposure receptor to volcanic ash." []
synonym: "volcanic ash exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000701 ! has exposure stimulus volcanic ash
relationship: RO:0002309 ENVO:01000701 ! has exposure stimulus volcanic ash

[Term]
id: ECTO:7000073
name: exposure to mineral material
def: "A exposure event involving the interaction of an exposure receptor to mineral material." []
synonym: "mineral material exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000256 ! has exposure stimulus mineral material
relationship: RO:0002309 ENVO:01000256 ! has exposure stimulus mineral material

[Term]
id: ECTO:7000074
name: exposure to mine tailing
def: "A exposure event involving the interaction of an exposure receptor to mine tailing." []
synonym: "mine tailing exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00000003 ! has exposure stimulus mine tailing
relationship: RO:0002309 ENVO:00000003 ! has exposure stimulus mine tailing

[Term]
id: ECTO:7000075
name: exposure to permafrost
def: "A exposure event involving the interaction of an exposure receptor to permafrost." []
synonym: "permafrost exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00000134 ! has exposure stimulus permafrost
relationship: RO:0002309 ENVO:00000134 ! has exposure stimulus permafrost

[Term]
id: ECTO:7000076
name: exposure to waste water
def: "A exposure event involving the interaction of an exposure receptor to waste water." []
synonym: "waste water exposure" EXACT []
is_a: ECTO:7000092 ! exposure to waste material
is_a: ECTO:7000119 ! exposure to contaminated water
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002001 ! has exposure stimulus waste water
relationship: RO:0002309 ENVO:00002001 ! has exposure stimulus waste water

[Term]
id: ECTO:7000077
name: exposure to feces
def: "A exposure event involving the interaction of an exposure receptor to fecal material." []
synonym: "fecal material exposure" EXACT []
is_a: ECTO:7000112 ! exposure to excreta
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002003 ! has exposure stimulus fecal material
relationship: RO:0002309 ENVO:00002003 ! has exposure stimulus fecal material

[Term]
id: ECTO:7000078
name: exposure to sewage
def: "A exposure event involving the interaction of an exposure receptor to sewage." []
synonym: "sewage exposure" EXACT []
is_a: ECTO:7000076 ! exposure to waste water
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002018 ! has exposure stimulus sewage
relationship: RO:0002309 ENVO:00002018 ! has exposure stimulus sewage

[Term]
id: ECTO:7000079
name: exposure to raw primary sludge
def: "A exposure event involving the interaction of an exposure receptor to raw primary sludge." []
synonym: "raw primary sludge exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002057 ! has exposure stimulus raw primary sludge
relationship: RO:0002309 ENVO:00002057 ! has exposure stimulus raw primary sludge

[Term]
id: ECTO:7000080
name: exposure to secondary sludge
def: "A exposure event involving the interaction of an exposure receptor to secondary sludge." []
synonym: "secondary sludge exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002058 ! has exposure stimulus secondary sludge
relationship: RO:0002309 ENVO:00002058 ! has exposure stimulus secondary sludge

[Term]
id: ECTO:7000081
name: exposure to biosolids
def: "A exposure event involving the interaction of an exposure receptor to biosolids." []
synonym: "biosolids exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002059 ! has exposure stimulus biosolids
relationship: RO:0002309 ENVO:00002059 ! has exposure stimulus biosolids

[Term]
id: ECTO:7000082
name: exposure to oil sludge
def: "A exposure event involving the interaction of an exposure receptor to oil sludge." []
synonym: "oil sludge exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002060 ! has exposure stimulus oil sludge
relationship: RO:0002309 ENVO:00002060 ! has exposure stimulus oil sludge

[Term]
id: ECTO:7000083
name: exposure to contaminated sediment
def: "A exposure event involving the interaction of an exposure receptor to chemically enriched sediment." []
synonym: "chemically enriched sediment exposure" EXACT []
is_a: ECTO:7000068 ! exposure to particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002114 ! has exposure stimulus chemically enriched sediment
relationship: RO:0002309 ENVO:00002114 ! has exposure stimulus chemically enriched sediment

[Term]
id: ECTO:7000084
name: exposure to petroleum contaminated sediment
def: "A exposure event involving the interaction of an exposure receptor to petroleum enriched sediment." []
synonym: "petroleum enriched sediment exposure" EXACT []
is_a: ECTO:7000083 ! exposure to contaminated sediment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002115 ! has exposure stimulus petroleum enriched sediment
relationship: RO:0002309 ENVO:00002115 ! has exposure stimulus petroleum enriched sediment

[Term]
id: ECTO:7000085
name: exposure to contaminated soil
def: "A exposure event involving the interaction of an exposure receptor to contaminated soil." []
synonym: "contaminated soil exposure" EXACT []
is_a: ECTO:7000012 ! exposure to soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002116 ! has exposure stimulus contaminated soil
relationship: RO:0002309 ENVO:00002116 ! has exposure stimulus contaminated soil

[Term]
id: ECTO:7000086
name: exposure to creosote contaminated soil
def: "A exposure event involving the interaction of an exposure receptor to creosote contaminated soil." []
synonym: "creosote contaminated soil exposure" EXACT []
is_a: ECTO:7000085 ! exposure to contaminated soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002117 ! has exposure stimulus creosote contaminated soil
relationship: RO:0002309 ENVO:00002117 ! has exposure stimulus creosote contaminated soil

[Term]
id: ECTO:7000087
name: exposure to arsenic-rich mud
def: "A exposure event involving the interaction of an exposure receptor to arsenic-rich mud." []
synonym: "arsenic-rich mud exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002122 ! has exposure stimulus arsenic-rich mud
relationship: RO:0002309 ENVO:00002122 ! has exposure stimulus arsenic-rich mud

[Term]
id: ECTO:7000088
name: exposure to borax leachate
def: "A exposure event involving the interaction of an exposure receptor to borax leachate." []
synonym: "borax leachate exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002142 ! has exposure stimulus borax leachate
relationship: RO:0002309 ENVO:00002142 ! has exposure stimulus borax leachate

[Term]
id: ECTO:7000089
name: exposure to chromate contaminated soil
def: "A exposure event involving the interaction of an exposure receptor to chromate contaminated soil." []
synonym: "chromate contaminated soil exposure" EXACT []
is_a: ECTO:7000085 ! exposure to contaminated soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002145 ! has exposure stimulus chromate contaminated soil
relationship: RO:0002309 ENVO:00002145 ! has exposure stimulus chromate contaminated soil

[Term]
id: ECTO:7000090
name: exposure to xylene contaminated soil
def: "A exposure event involving the interaction of an exposure receptor to xylene contaminated soil." []
synonym: "xylene contaminated soil exposure" EXACT []
is_a: ECTO:7000085 ! exposure to contaminated soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002146 ! has exposure stimulus xylene contaminated soil
relationship: RO:0002309 ENVO:00002146 ! has exposure stimulus xylene contaminated soil

[Term]
id: ECTO:7000091
name: exposure to agricultural soil
def: "A exposure event involving the interaction of an exposure receptor to agricultural soil." []
synonym: "agricultural soil exposure" EXACT []
is_a: ECTO:7000012 ! exposure to soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002259 ! has exposure stimulus agricultural soil
relationship: RO:0002309 ENVO:00002259 ! has exposure stimulus agricultural soil

[Term]
id: ECTO:7000092
name: exposure to waste material
def: "A exposure event involving the interaction of an exposure receptor to waste material." []
synonym: "waste material exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002264 ! has exposure stimulus waste material
relationship: RO:0002309 ENVO:00002264 ! has exposure stimulus waste material

[Term]
id: ECTO:7000093
name: exposure to chicken breeding waste material
def: "A exposure event involving the interaction of an exposure receptor to chicken breeding waste material." []
synonym: "chicken breeding waste material exposure" EXACT []
is_a: ECTO:7000092 ! exposure to waste material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002266 ! has exposure stimulus chicken breeding waste material
relationship: RO:0002309 ENVO:00002266 ! has exposure stimulus chicken breeding waste material

[Term]
id: ECTO:7000094
name: exposure to industrial waste material
def: "A exposure event involving the interaction of an exposure receptor to industrial waste material." []
synonym: "industrial waste material exposure" EXACT []
is_a: ECTO:7000092 ! exposure to waste material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002267 ! has exposure stimulus industrial waste material
relationship: RO:0002309 ENVO:00002267 ! has exposure stimulus industrial waste material

[Term]
id: ECTO:7000095
name: exposure to fluvisol
def: "A exposure event involving the interaction of an exposure receptor to fluvisol." []
synonym: "fluvisol exposure" EXACT []
is_a: ECTO:7000012 ! exposure to soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002273 ! has exposure stimulus fluvisol
relationship: RO:0002309 ENVO:00002273 ! has exposure stimulus fluvisol

[Term]
id: ECTO:7000096
name: exposure to stagnosol
def: "A exposure event involving the interaction of an exposure receptor to stagnosol." []
synonym: "stagnosol exposure" EXACT []
is_a: ECTO:7000012 ! exposure to soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002274 ! has exposure stimulus stagnosol
relationship: RO:0002309 ENVO:00002274 ! has exposure stimulus stagnosol

[Term]
id: ECTO:7000097
name: exposure to technosol
def: "A exposure event involving the interaction of an exposure receptor to technosol." []
synonym: "technosol exposure" EXACT []
is_a: ECTO:7000012 ! exposure to soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002275 ! has exposure stimulus technosol
relationship: RO:0002309 ENVO:00002275 ! has exposure stimulus technosol

[Term]
id: ECTO:7000098
name: exposure to animal waste material
def: "A exposure event involving the interaction of an exposure receptor to animal waste material." []
synonym: "animal waste material exposure" EXACT []
is_a: ECTO:7000102 ! exposure to organic waste material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002276 ! has exposure stimulus animal waste material
relationship: RO:0002309 ENVO:00002276 ! has exposure stimulus animal waste material

[Term]
id: ECTO:7000099
name: exposure to hay
def: "A exposure event involving the interaction of an exposure receptor to hay." []
synonym: "hay exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002869 ! has exposure stimulus hay
relationship: RO:0002309 ENVO:00002869 ! has exposure stimulus hay

[Term]
id: ECTO:7000100
name: exposure to adobe
def: "A exposure event involving the interaction of an exposure receptor to adobe." []
synonym: "adobe exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002870 ! has exposure stimulus adobe
relationship: RO:0002309 ENVO:00002870 ! has exposure stimulus adobe

[Term]
id: ECTO:7000101
name: exposure to bagasse
def: "A exposure event involving the interaction of an exposure receptor to bagasse." []
synonym: "bagasse exposure" EXACT []
is_a: ECTO:7000092 ! exposure to waste material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002872 ! has exposure stimulus bagasse
relationship: RO:0002309 ENVO:00002872 ! has exposure stimulus bagasse

[Term]
id: ECTO:7000102
name: exposure to organic waste material
def: "A exposure event involving the interaction of an exposure receptor to organic waste material." []
synonym: "organic waste material exposure" EXACT []
is_a: ECTO:7000092 ! exposure to waste material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002873 ! has exposure stimulus organic waste material
relationship: RO:0002309 ENVO:00002873 ! has exposure stimulus organic waste material

[Term]
id: ECTO:7000103
name: exposure to oil contaminated soil
def: "A exposure event involving the interaction of an exposure receptor to oil contaminated soil." []
synonym: "oil contaminated soil exposure" EXACT []
is_a: ECTO:7000085 ! exposure to contaminated soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002875 ! has exposure stimulus oil contaminated soil
relationship: RO:0002309 ENVO:00002875 ! has exposure stimulus oil contaminated soil

[Term]
id: ECTO:7000104
name: exposure to fuel oil
def: "A exposure event involving the interaction of an exposure receptor to fuel oil." []
synonym: "fuel oil exposure" EXACT []
is_a: ECTO:7000067 ! exposure to oil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002983 ! has exposure stimulus fuel oil
relationship: RO:0002309 ENVO:00002983 ! has exposure stimulus fuel oil

[Term]
id: ECTO:7000105
name: exposure to petroleum
def: "A exposure event involving the interaction of an exposure receptor to petroleum." []
synonym: "petroleum exposure" EXACT []
is_a: ECTO:7000067 ! exposure to oil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002984 ! has exposure stimulus petroleum
relationship: RO:0002309 ENVO:00002984 ! has exposure stimulus petroleum

[Term]
id: ECTO:7000106
name: exposure to silage
def: "A exposure event involving the interaction of an exposure receptor to silage." []
synonym: "silage exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003030 ! has exposure stimulus silage
relationship: RO:0002309 ENVO:00003030 ! has exposure stimulus silage

[Term]
id: ECTO:7000107
name: exposure to animal manure
def: "A exposure event involving the interaction of an exposure receptor to animal manure." []
synonym: "animal manure exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003031 ! has exposure stimulus animal manure
relationship: RO:0002309 ENVO:00003031 ! has exposure stimulus animal manure

[Term]
id: ECTO:7000108
name: exposure to fresh animal manure
def: "A exposure event involving the interaction of an exposure receptor to fresh animal manure." []
synonym: "fresh animal manure exposure" EXACT []
is_a: ECTO:7000107 ! exposure to animal manure
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003032 ! has exposure stimulus fresh animal manure
relationship: RO:0002309 ENVO:00003032 ! has exposure stimulus fresh animal manure

[Term]
id: ECTO:7000109
name: exposure to bodily fluid
def: "A exposure event involving the interaction of an exposure receptor to bodily fluid material." []
synonym: "bodily fluid material exposure" EXACT []
is_a: ECTO:7000069 ! exposure to organic material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000019 ! has exposure stimulus bodily fluid material
relationship: RO:0002309 ENVO:02000019 ! has exposure stimulus bodily fluid material

[Term]
id: ECTO:7000110
name: exposure to blood
def: "A exposure event involving the interaction of an exposure receptor to blood material." []
synonym: "blood material exposure" EXACT []
is_a: ECTO:7000109 ! exposure to bodily fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000020 ! has exposure stimulus blood material
relationship: RO:0002309 ENVO:02000020 ! has exposure stimulus blood material

[Term]
id: ECTO:7000111
name: exposure to amniotic fluid
def: "A exposure event involving the interaction of an exposure receptor to amniotic fluid material." []
synonym: "amniotic fluid material exposure" EXACT []
is_a: ECTO:7000109 ! exposure to bodily fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000021 ! has exposure stimulus amniotic fluid material
relationship: RO:0002309 ENVO:02000021 ! has exposure stimulus amniotic fluid material

[Term]
id: ECTO:7000112
name: exposure to excreta
def: "A exposure event involving the interaction of an exposure receptor to excreta material." []
synonym: "excreta material exposure" EXACT []
is_a: ECTO:7000092 ! exposure to waste material
is_a: ECTO:7000109 ! exposure to bodily fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000022 ! has exposure stimulus excreta material
relationship: RO:0002309 ENVO:02000022 ! has exposure stimulus excreta material

[Term]
id: ECTO:7000113
name: exposure to bile
def: "A exposure event involving the interaction of an exposure receptor to bile material." []
synonym: "bile material exposure" EXACT []
is_a: ECTO:7000109 ! exposure to bodily fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000023 ! has exposure stimulus bile material
relationship: RO:0002309 ENVO:02000023 ! has exposure stimulus bile material

[Term]
id: ECTO:7000114
name: exposure to aerosol
def: "A exposure event involving the interaction of an exposure receptor to aerosol." []
synonym: "aerosol exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00010505 ! has exposure stimulus aerosol
relationship: RO:0002309 ENVO:00010505 ! has exposure stimulus aerosol

[Term]
id: ECTO:7000115
name: exposure to waterborne particulate matter
def: "A exposure event involving the interaction of an exposure receptor to waterborne particulate matter." []
synonym: "waterborne particulate matter exposure" EXACT []
is_a: ECTO:7000068 ! exposure to particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000436 ! has exposure stimulus waterborne particulate matter
relationship: RO:0002309 ENVO:01000436 ! has exposure stimulus waterborne particulate matter

[Term]
id: ECTO:7000116
name: exposure to respirable suspended particulate matter
def: "A exposure event involving the interaction of an exposure receptor to respirable suspended particulate matter." []
synonym: "respirable suspended particulate matter exposure" EXACT []
is_a: ECTO:7000114 ! exposure to aerosol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000405 ! has exposure stimulus respirable suspended particulate matter
relationship: RO:0002309 ENVO:01000405 ! has exposure stimulus respirable suspended particulate matter

[Term]
id: ECTO:7000117
name: exposure to fine respirable suspended particulate matter
def: "A exposure event involving the interaction of an exposure receptor to fine respirable suspended particulate matter." []
synonym: "fine respirable suspended particulate matter exposure" EXACT []
is_a: ECTO:7000116 ! exposure to respirable suspended particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000415 ! has exposure stimulus fine respirable suspended particulate matter
relationship: RO:0002309 ENVO:01000415 ! has exposure stimulus fine respirable suspended particulate matter

[Term]
id: ECTO:7000118
name: exposure to ultrafine respirable suspended particulate matter
def: "A exposure event involving the interaction of an exposure receptor to ultrafine respirable suspended particulate matter." []
synonym: "ultrafine respirable suspended particulate matter exposure" EXACT []
is_a: ECTO:7000117 ! exposure to fine respirable suspended particulate matter
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000416 ! has exposure stimulus ultrafine respirable suspended particulate matter
relationship: RO:0002309 ENVO:01000416 ! has exposure stimulus ultrafine respirable suspended particulate matter

[Term]
id: ECTO:7000119
name: exposure to contaminated water
def: "A exposure event involving the interaction of an exposure receptor to contaminated water." []
synonym: "contaminated water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002186 ! has exposure stimulus contaminated water
relationship: RO:0002309 ENVO:00002186 ! has exposure stimulus contaminated water

[Term]
id: ECTO:7000120
name: exposure to pulp-bleaching waste water
def: "A exposure event involving the interaction of an exposure receptor to pulp-bleaching waste water." []
synonym: "pulp-bleaching waste water exposure" EXACT []
is_a: ECTO:7000076 ! exposure to waste water
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002193 ! has exposure stimulus pulp-bleaching waste water
relationship: RO:0002309 ENVO:00002193 ! has exposure stimulus pulp-bleaching waste water

[Term]
id: ECTO:7000122
name: exposure to sea water
def: "A exposure event involving the interaction of an exposure receptor to sea water." []
synonym: "sea water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002149 ! has exposure stimulus sea water
relationship: RO:0002309 ENVO:00002149 ! has exposure stimulus sea water

[Term]
id: ECTO:7000123
name: exposure to river water
def: "A exposure event involving the interaction of an exposure receptor to river water." []
synonym: "river water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000599 ! has exposure stimulus river water
relationship: RO:0002309 ENVO:01000599 ! has exposure stimulus river water

[Term]
id: ECTO:7000124
name: exposure to distilled water
def: "A exposure event involving the interaction of an exposure receptor to distilled water." []
synonym: "distilled water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003065 ! has exposure stimulus distilled water
relationship: RO:0002309 ENVO:00003065 ! has exposure stimulus distilled water

[Term]
id: ECTO:7000125
name: exposure to drinking water
def: "A exposure event involving the interaction of an exposure receptor to drinking water." []
synonym: "drinking water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003064 ! has exposure stimulus drinking water
relationship: RO:0002309 ENVO:00003064 ! has exposure stimulus drinking water

[Term]
id: ECTO:7000126
name: exposure to tap water
def: "A exposure event involving the interaction of an exposure receptor to tap water." []
synonym: "tap water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003096 ! has exposure stimulus tap water
relationship: RO:0002309 ENVO:00003096 ! has exposure stimulus tap water

[Term]
id: ECTO:7000127
name: exposure to groundwater
def: "A exposure event involving the interaction of an exposure receptor to groundwater." []
synonym: "groundwater exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001004 ! has exposure stimulus groundwater
relationship: RO:0002309 ENVO:01001004 ! has exposure stimulus groundwater

[Term]
id: ECTO:7000128
name: exposure to pond water
def: "A exposure event involving the interaction of an exposure receptor to pond water." []
synonym: "pond water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002228 ! has exposure stimulus pond water
relationship: RO:0002309 ENVO:00002228 ! has exposure stimulus pond water

[Term]
id: ECTO:7000129
name: exposure to welding fume
def: "A exposure event involving the interaction of an exposure receptor to welding fume." []
synonym: "welding fume exposure" EXACT []
is_a: ECTO:7000002 ! exposure to fumes
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000113 ! has exposure stimulus welding fume
relationship: RO:0002309 ENVO:02000113 ! has exposure stimulus welding fume

[Term]
id: ECTO:7000130
name: exposure to glue
def: "A exposure event involving the interaction of an exposure receptor to glue." []
synonym: "glue exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00003076 ! has exposure stimulus glue
relationship: RO:0002309 ENVO:00003076 ! has exposure stimulus glue

[Term]
id: ECTO:7000131
name: exposure to resin
def: "A exposure event involving the interaction of an exposure receptor to resin." []
synonym: "resin exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510018 ! has exposure stimulus resin
relationship: RO:0002309 ENVO:03510018 ! has exposure stimulus resin

[Term]
id: ECTO:7000132
name: exposure to shellac
def: "A exposure event involving the interaction of an exposure receptor to shellac." []
synonym: "shellac exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510023 ! has exposure stimulus shellac
relationship: RO:0002309 ENVO:03510023 ! has exposure stimulus shellac

[Term]
id: ECTO:7000133
name: exposure to tragacanth
def: "A exposure event involving the interaction of an exposure receptor to tragacanth." []
synonym: "tragacanth exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510016 ! has exposure stimulus tragacanth
relationship: RO:0002309 ENVO:03510016 ! has exposure stimulus tragacanth

[Term]
id: ECTO:7000134
name: exposure to xanthan gum
def: "A exposure event involving the interaction of an exposure receptor to xanthan gum." []
synonym: "xanthan gum exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510015 ! has exposure stimulus xanthan gum
relationship: RO:0002309 ENVO:03510015 ! has exposure stimulus xanthan gum

[Term]
id: ECTO:7000135
name: exposure to wood dust
def: "A exposure event involving the interaction of an exposure receptor to wood dust." []
synonym: "wood dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510000 ! has exposure stimulus wood dust
relationship: RO:0002309 ENVO:03510000 ! has exposure stimulus wood dust

[Term]
id: ECTO:7000136
name: exposure to diesel fuel
def: "A exposure event involving the interaction of an exposure receptor to diesel fuel." []
synonym: "diesel fuel exposure" EXACT []
is_a: ECTO:7000105 ! exposure to petroleum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510006 ! has exposure stimulus diesel fuel
relationship: RO:0002309 ENVO:03510006 ! has exposure stimulus diesel fuel

[Term]
id: ECTO:7000137
name: exposure to gasoline
def: "A exposure event involving the interaction of an exposure receptor to gasoline." []
synonym: "gasoline exposure" EXACT []
is_a: ECTO:7000105 ! exposure to petroleum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510007 ! has exposure stimulus gasoline
relationship: RO:0002309 ENVO:03510007 ! has exposure stimulus gasoline

[Term]
id: ECTO:7000138
name: exposure to diesel exhaust
def: "A exposure event involving the interaction of an exposure receptor to diesel exhaust." []
synonym: "diesel exhaust exposure" EXACT []
is_a: ECTO:7000058 ! exposure to gaseous environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510008 ! has exposure stimulus diesel exhaust
relationship: RO:0002309 ENVO:03510008 ! has exposure stimulus diesel exhaust

[Term]
id: ECTO:7000139
name: exposure to gasoline exhaust
def: "A exposure event involving the interaction of an exposure receptor to gasoline exhaust." []
synonym: "gasoline exhaust exposure" EXACT []
is_a: ECTO:7000058 ! exposure to gaseous environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510009 ! has exposure stimulus gasoline exhaust
relationship: RO:0002309 ENVO:03510009 ! has exposure stimulus gasoline exhaust

[Term]
id: ECTO:7000140
name: exposure to primer (paint)
def: "A exposure event involving the interaction of an exposure receptor to primer (paint)." []
synonym: "primer (paint) exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510029 ! has exposure stimulus primer (paint)
relationship: RO:0002309 ENVO:03510029 ! has exposure stimulus primer (paint)

[Term]
id: ECTO:7000141
name: exposure to oil-based paint
def: "A exposure event involving the interaction of an exposure receptor to oil-based paint." []
synonym: "oil-based paint exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510031 ! has exposure stimulus oil-based paint
relationship: RO:0002309 ENVO:03510031 ! has exposure stimulus oil-based paint

[Term]
id: ECTO:7000142
name: exposure to acrylic paint
def: "A exposure event involving the interaction of an exposure receptor to acrylic paint." []
synonym: "acrylic paint exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510032 ! has exposure stimulus acrylic paint
relationship: RO:0002309 ENVO:03510032 ! has exposure stimulus acrylic paint

[Term]
id: ECTO:7000143
name: exposure to luminescent paint
def: "A exposure event involving the interaction of an exposure receptor to luminescent paint." []
synonym: "luminescent paint exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510033 ! has exposure stimulus luminescent paint
relationship: RO:0002309 ENVO:03510033 ! has exposure stimulus luminescent paint

[Term]
id: ECTO:7000144
name: exposure to rock dust
def: "A exposure event involving the interaction of an exposure receptor to rock dust." []
synonym: "rock dust exposure" EXACT []
is_a: ECTO:7000001 ! exposure to dust
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510036 ! has exposure stimulus rock dust
relationship: RO:0002309 ENVO:03510036 ! has exposure stimulus rock dust

[Term]
id: ECTO:7000145
name: exposure to radioactive material
def: "A exposure event involving the interaction of an exposure receptor to radioactive material." []
synonym: "radioactive material exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510037 ! has exposure stimulus radioactive material
relationship: RO:0002309 ENVO:03510037 ! has exposure stimulus radioactive material

[Term]
id: ECTO:7000146
name: exposure to cyanoacrylate
def: "A exposure event involving the interaction of an exposure receptor to volume of cyanoacrylate." []
synonym: "volume of cyanoacrylate exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510038 ! has exposure stimulus volume of cyanoacrylate
relationship: RO:0002309 ENVO:03510038 ! has exposure stimulus volume of cyanoacrylate

[Term]
id: ECTO:7000147
name: exposure to plastic production compound
def: "A exposure event involving the interaction of an exposure receptor to a plastic production compound." []
is_a: ExO:0000002 ! exposure event

[Term]
id: ECTO:7000148
name: exposure to cotton dust
def: "A exposure event involving the interaction of an exposure receptor to cotton dust." []
synonym: "cotton dust exposure" EXACT []
is_a: ECTO:7000033 ! exposure to dust from plant parts
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000108 ! has exposure stimulus cotton dust
relationship: RO:0002309 ENVO:02000108 ! has exposure stimulus cotton dust

[Term]
id: ECTO:7000149
name: exposure to rubber cement
def: "A exposure event involving the interaction of an exposure receptor to rubber cement." []
synonym: "rubber cement exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510055 ! has exposure stimulus rubber cement
relationship: RO:0002309 ENVO:03510055 ! has exposure stimulus rubber cement

[Term]
id: ECTO:7000150
name: exposure to methyl cellulose paste
def: "A exposure event involving the interaction of an exposure receptor to methyl cellulose paste." []
synonym: "methyl cellulose paste exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
is_a: ECTO:7000069 ! exposure to organic material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510056 ! has exposure stimulus methyl cellulose paste
relationship: RO:0002309 ENVO:03510056 ! has exposure stimulus methyl cellulose paste

[Term]
id: ECTO:7000151
name: exposure to permanent hair dye
def: "A exposure event involving the interaction of an exposure receptor to permanent hair dye." []
synonym: "permanent hair dye exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510057 ! has exposure stimulus permanent hair dye
relationship: RO:0002309 ENVO:03510057 ! has exposure stimulus permanent hair dye

[Term]
id: ECTO:7000152
name: exposure to pharmaceutical ink
def: "A exposure event involving the interaction of an exposure receptor to pharmaceutical ink." []
synonym: "pharmaceutical ink exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
is_a: ECTO:7000157 ! exposure to colorant fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510058 ! has exposure stimulus pharmaceutical ink
relationship: RO:0002309 ENVO:03510058 ! has exposure stimulus pharmaceutical ink

[Term]
id: ECTO:7000153
name: exposure to gel ink
def: "A exposure event involving the interaction of an exposure receptor to gel ink." []
synonym: "gel ink exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
is_a: ECTO:7000157 ! exposure to colorant fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510060 ! has exposure stimulus gel ink
relationship: RO:0002309 ENVO:03510060 ! has exposure stimulus gel ink

[Term]
id: ECTO:7000154
name: exposure to soy ink
def: "A exposure event involving the interaction of an exposure receptor to soy ink." []
synonym: "soy ink exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
is_a: ECTO:7000157 ! exposure to colorant fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510061 ! has exposure stimulus soy ink
relationship: RO:0002309 ENVO:03510061 ! has exposure stimulus soy ink

[Term]
id: ECTO:7000155
name: exposure to aqueous inkjet printer ink
def: "A exposure event involving the interaction of an exposure receptor to aqueous inkjet printer ink." []
synonym: "aqueous inkjet printer ink exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
is_a: ECTO:7000157 ! exposure to colorant fluid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510062 ! has exposure stimulus aqueous inkjet printer ink
relationship: RO:0002309 ENVO:03510062 ! has exposure stimulus aqueous inkjet printer ink

[Term]
id: ECTO:7000156
name: exposure to emissions from petroleum combustion
def: "A exposure event involving the interaction of an exposure receptor to emissions from petroleum combustion." []
synonym: "emissions from petroleum combustion exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510064 ! has exposure stimulus emissions from petroleum combustion
relationship: RO:0002309 ENVO:03510064 ! has exposure stimulus emissions from petroleum combustion

[Term]
id: ECTO:7000157
name: exposure to colorant fluid
def: "A exposure event involving the interaction of an exposure receptor to colorant fluid." []
synonym: "colorant fluid exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510065 ! has exposure stimulus colorant fluid
relationship: RO:0002309 ENVO:03510065 ! has exposure stimulus colorant fluid

[Term]
id: ECTO:7000158
name: exposure to chemical colorant
def: "A exposure event involving the interaction of an exposure receptor to chemical colorant." []
synonym: "chemical colorant exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03510066 ! has exposure stimulus chemical colorant
relationship: RO:0002309 ENVO:03510066 ! has exposure stimulus chemical colorant

[Term]
id: ECTO:7000159
name: exposure to fly ash
def: "A exposure event involving the interaction of an exposure receptor to fly ash." []
synonym: "fly ash exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02000128 ! has exposure stimulus fly ash
relationship: RO:0002309 ENVO:02000128 ! has exposure stimulus fly ash

[Term]
id: ECTO:7000160
name: exposure to plastic
def: "A exposure event involving the interaction of an exposure receptor to plastic." []
synonym: "plastic exposure" EXACT []
is_a: ECTO:0000015 ! exposure to environmental material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:06105101 ! has exposure stimulus plastic
relationship: RO:0002309 ENVO:06105101 ! has exposure stimulus plastic

[Term]
id: ECTO:7000161
name: exposure to saline water environment
def: "A exposure event involving the interaction of an exposure receptor to saline water environment." []
synonym: "saline water environment exposure" EXACT []
is_a: ECTO:1000046 ! exposure to high osmolarity environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000307 ! has exposure stimulus saline water environment
relationship: RO:0002309 ENVO:01000307 ! has exposure stimulus saline water environment

[Term]
id: ECTO:7000162
name: exposure to sea water environment
def: "A exposure event involving the interaction of an exposure receptor to sea water environment." []
synonym: "sea water environment exposure" EXACT []
is_a: ECTO:7000161 ! exposure to saline water environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000321 ! has exposure stimulus sea water environment
relationship: RO:0002309 ENVO:01000321 ! has exposure stimulus sea water environment

[Term]
id: ECTO:7000163
name: exposure to soil organic matter
def: "A exposure event involving the interaction of an exposure receptor to soil organic matter." []
synonym: "soil organic matter exposure" EXACT []
is_a: ECTO:7000069 ! exposure to organic material
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:04000008 ! has exposure stimulus soil organic matter
relationship: RO:0002309 ENVO:04000008 ! has exposure stimulus soil organic matter

[Term]
id: ECTO:7000164
name: exposure to treated wastewater
def: "A exposure event involving the interaction of an exposure receptor to treated wastewater." []
synonym: "treated wastewater exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:06105268 ! has exposure stimulus treated wastewater
relationship: RO:0002309 ENVO:06105268 ! has exposure stimulus treated wastewater

[Term]
id: ECTO:7000165
name: exposure to water-based cloud droplet
def: "A exposure event involving the interaction of an exposure receptor to water-based cloud droplet." []
synonym: "water-based cloud droplet exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000836 ! has exposure stimulus water-based cloud droplet
relationship: RO:0002309 ENVO:01000836 ! has exposure stimulus water-based cloud droplet

[Term]
id: ECTO:7000166
name: exposure to clay soil
def: "A exposure event involving the interaction of an exposure receptor to clay soil." []
synonym: "clay soil exposure" EXACT []
is_a: ECTO:7000012 ! exposure to soil
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:00002262 ! has exposure stimulus clay soil
relationship: RO:0002309 ENVO:00002262 ! has exposure stimulus clay soil

[Term]
id: ECTO:7000167
name: exposure to smokeless tobacco
def: "A exposure event involving the interaction of an exposure receptor to smokeless tobacco." []
synonym: "smokeless tobacco exposure" EXACT []
is_a: ECTO:0500025 ! exposure to manufactured product
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03600049 ! has exposure stimulus smokeless tobacco
relationship: RO:0002309 ENVO:03600049 ! has exposure stimulus smokeless tobacco

[Term]
id: ECTO:7000168
name: exposure to highly saline water
def: "A exposure event involving the interaction of an exposure receptor to highly saline water." []
synonym: "highly saline water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001039 ! has exposure stimulus highly saline water
relationship: RO:0002309 ENVO:01001039 ! has exposure stimulus highly saline water

[Term]
id: ECTO:7000169
name: exposure to atmosphere
def: "A exposure event involving the interaction of an exposure receptor to atmosphere." []
synonym: "atmosphere exposure" EXACT []
is_a: ECTO:0400000 ! exposure to environmental layer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000267 ! has exposure stimulus atmosphere
relationship: RO:0002309 ENVO:01000267 ! has exposure stimulus atmosphere

[Term]
id: ECTO:7000170
name: exposure to cloud water
def: "A exposure event involving the interaction of an exposure receptor to cloud water." []
synonym: "cloud water exposure" EXACT []
is_a: ECTO:7000063 ! exposure to water in environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03600081 ! has exposure stimulus cloud water
relationship: RO:0002309 ENVO:03600081 ! has exposure stimulus cloud water

[Term]
id: ECTO:8000000
name: exposure to environmental process
def: "A exposure event involving the interaction of an exposure receptor to environmental system process." []
synonym: "environmental system process exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500000 ! has exposure stimulus environmental system process
relationship: RO:0002309 ENVO:02500000 ! has exposure stimulus environmental system process

[Term]
id: ECTO:8000001
name: exposure to methane gas emission process
def: "A exposure event involving the interaction of an exposure receptor to methane gas emission process." []
synonym: "methane gas emission process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03000094 ! has exposure stimulus methane gas emission process
relationship: RO:0002309 ENVO:03000094 ! has exposure stimulus methane gas emission process

[Term]
id: ECTO:8000002
name: exposure to atmospheric aerosolisation of dust
def: "A exposure event involving the interaction of an exposure receptor to atmospheric aerosolisation of dust." []
synonym: "atmospheric aerosolisation of dust exposure" EXACT []
is_a: ECTO:8000003 ! exposure to aerosolisation of dust
is_a: ECTO:8000017 ! exposure to atmospheric process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001399 ! has exposure stimulus atmospheric aerosolisation of dust
relationship: RO:0002309 ENVO:01001399 ! has exposure stimulus atmospheric aerosolisation of dust

[Term]
id: ECTO:8000003
name: exposure to aerosolisation of dust
def: "A exposure event involving the interaction of an exposure receptor to aerosolisation of dust." []
synonym: "aerosolisation of dust exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001398 ! has exposure stimulus aerosolisation of dust
relationship: RO:0002309 ENVO:01001398 ! has exposure stimulus aerosolisation of dust

[Term]
id: ECTO:8000004
name: exposure to lumber production process
def: "A exposure event involving the interaction of an exposure receptor to lumber production process." []
synonym: "lumber production process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001223 ! has exposure stimulus lumber production process
relationship: RO:0002309 ENVO:01001223 ! has exposure stimulus lumber production process

[Term]
id: ECTO:8000005
name: exposure to greenhouse effect
def: "A exposure event involving the interaction of an exposure receptor to greenhouse effect." []
synonym: "greenhouse effect exposure" EXACT []
is_a: ECTO:8000017 ! exposure to atmospheric process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500004 ! has exposure stimulus greenhouse effect
relationship: RO:0002309 ENVO:02500004 ! has exposure stimulus greenhouse effect

[Term]
id: ECTO:8000006
name: exposure to combusion process
def: "A exposure event involving the interaction of an exposure receptor to combustion process." []
synonym: "combustion process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000839 ! has exposure stimulus combustion process
relationship: RO:0002309 ENVO:01000839 ! has exposure stimulus combustion process

[Term]
id: ECTO:8000007
name: exposure to plastic pollution
def: "A exposure event involving the interaction of an exposure receptor to plastic pollution." []
synonym: "plastic pollution exposure" EXACT []
is_a: ECTO:8000019 ! exposure to environmental pollution
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500040 ! has exposure stimulus plastic pollution
relationship: RO:0002309 ENVO:02500040 ! has exposure stimulus plastic pollution

[Term]
id: ECTO:8000008
name: exposure to climate change
def: "A exposure event involving the interaction of an exposure receptor to climate change." []
synonym: "climate change exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000629 ! has exposure stimulus climate change
relationship: RO:0002309 ENVO:01000629 ! has exposure stimulus climate change

[Term]
id: ECTO:8000009
name: exposure to acidification of an aquatic environment
def: "A exposure event involving the interaction of an exposure receptor to acidification of an aquatic environment." []
synonym: "acidification of an aquatic environment exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000630 ! has exposure stimulus acidification of an aquatic environment
relationship: RO:0002309 ENVO:01000630 ! has exposure stimulus acidification of an aquatic environment

[Term]
id: ECTO:8000010
name: exposure to volcanic eruption
def: "A exposure event involving the interaction of an exposure receptor to volcanic eruption." []
synonym: "volcanic eruption exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000634 ! has exposure stimulus volcanic eruption
relationship: RO:0002309 ENVO:01000634 ! has exposure stimulus volcanic eruption

[Term]
id: ECTO:8000011
name: exposure to earthquake
def: "A exposure event involving the interaction of an exposure receptor to earthquake." []
synonym: "earthquake exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000677 ! has exposure stimulus earthquake
relationship: RO:0002309 ENVO:01000677 ! has exposure stimulus earthquake

[Term]
id: ECTO:8000012
name: exposure to tsunami
def: "A exposure event involving the interaction of an exposure receptor to tsunami." []
synonym: "tsunami exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000689 ! has exposure stimulus tsunami
relationship: RO:0002309 ENVO:01000689 ! has exposure stimulus tsunami

[Term]
id: ECTO:8000013
name: exposure to soil degradation
def: "A exposure event involving the interaction of an exposure receptor to soil degradation." []
synonym: "soil degradation exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000705 ! has exposure stimulus soil degradation
relationship: RO:0002309 ENVO:01000705 ! has exposure stimulus soil degradation

[Term]
id: ECTO:8000014
name: exposure to material extraction process
def: "A exposure event involving the interaction of an exposure receptor to material extraction process." []
synonym: "material extraction process exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000785 ! has exposure stimulus material extraction process
relationship: RO:0002309 ENVO:01000785 ! has exposure stimulus material extraction process

[Term]
id: ECTO:8000015
name: exposure to desertification
def: "A exposure event involving the interaction of an exposure receptor to desertification." []
synonym: "desertification exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500001 ! has exposure stimulus desertification
relationship: RO:0002309 ENVO:02500001 ! has exposure stimulus desertification

[Term]
id: ECTO:8000016
name: exposure to flooding
def: "A exposure event involving the interaction of an exposure receptor to flooding." []
synonym: "flooding exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500002 ! has exposure stimulus flooding
relationship: RO:0002309 ENVO:02500002 ! has exposure stimulus flooding

[Term]
id: ECTO:8000017
name: exposure to atmospheric process
def: "A exposure event involving the interaction of an exposure receptor to atmospheric process." []
synonym: "atmospheric process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500003 ! has exposure stimulus atmospheric process
relationship: RO:0002309 ENVO:02500003 ! has exposure stimulus atmospheric process

[Term]
id: ECTO:8000018
name: exposure to deforestation
def: "A exposure event involving the interaction of an exposure receptor to deforestation." []
synonym: "deforestation exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500012 ! has exposure stimulus deforestation
relationship: RO:0002309 ENVO:02500012 ! has exposure stimulus deforestation

[Term]
id: ECTO:8000019
name: exposure to environmental pollution
def: "A exposure event involving the interaction of an exposure receptor to environmental pollution." []
synonym: "environmental pollution exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500036 ! has exposure stimulus environmental pollution
relationship: RO:0002309 ENVO:02500036 ! has exposure stimulus environmental pollution

[Term]
id: ECTO:8000020
name: exposure to ocean acidification
def: "A exposure event involving the interaction of an exposure receptor to ocean acidification." []
synonym: "ocean acidification exposure" EXACT []
is_a: ECTO:8000009 ! exposure to acidification of an aquatic environment
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000631 ! has exposure stimulus ocean acidification
relationship: RO:0002309 ENVO:01000631 ! has exposure stimulus ocean acidification

[Term]
id: ECTO:8000021
name: exposure to tectonic earthquake
def: "A exposure event involving the interaction of an exposure receptor to tectonic earthquake." []
synonym: "tectonic earthquake exposure" EXACT []
is_a: ECTO:8000011 ! exposure to earthquake
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000678 ! has exposure stimulus tectonic earthquake
relationship: RO:0002309 ENVO:01000678 ! has exposure stimulus tectonic earthquake

[Term]
id: ECTO:8000022
name: exposure to landslide process
def: "A exposure event involving the interaction of an exposure receptor to landslide process." []
synonym: "landslide process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000692 ! has exposure stimulus landslide process
relationship: RO:0002309 ENVO:01000692 ! has exposure stimulus landslide process

[Term]
id: ECTO:8000023
name: exposure to mudslide
def: "A exposure event involving the interaction of an exposure receptor to mudslide." []
synonym: "mudslide exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000695 ! has exposure stimulus mudslide
relationship: RO:0002309 ENVO:01000695 ! has exposure stimulus mudslide

[Term]
id: ECTO:8000024
name: exposure to coastal flooding
def: "A exposure event involving the interaction of an exposure receptor to coastal flooding." []
synonym: "coastal flooding exposure" EXACT []
is_a: ECTO:8000016 ! exposure to flooding
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000707 ! has exposure stimulus coastal flooding
relationship: RO:0002309 ENVO:01000707 ! has exposure stimulus coastal flooding

[Term]
id: ECTO:8000025
name: exposure to riverine flooding
def: "A exposure event involving the interaction of an exposure receptor to riverine flooding." []
synonym: "riverine flooding exposure" EXACT []
is_a: ECTO:8000016 ! exposure to flooding
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000708 ! has exposure stimulus riverine flooding
relationship: RO:0002309 ENVO:01000708 ! has exposure stimulus riverine flooding

[Term]
id: ECTO:8000026
name: exposure to flash flooding
def: "A exposure event involving the interaction of an exposure receptor to flash flooding." []
synonym: "flash flooding exposure" EXACT []
is_a: ECTO:8000016 ! exposure to flooding
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000709 ! has exposure stimulus flash flooding
relationship: RO:0002309 ENVO:01000709 ! has exposure stimulus flash flooding

[Term]
id: ECTO:8000027
name: exposure to metotsunami
def: "A exposure event involving the interaction of an exposure receptor to meteotsunami." []
synonym: "meteotsunami exposure" EXACT []
is_a: ECTO:8000012 ! exposure to tsunami
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000715 ! has exposure stimulus meteotsunami
relationship: RO:0002309 ENVO:01000715 ! has exposure stimulus meteotsunami

[Term]
id: ECTO:8000028
name: exposure to storm surge process
def: "A exposure event involving the interaction of an exposure receptor to storm surge process." []
synonym: "storm surge process exposure" EXACT []
is_a: ECTO:8000024 ! exposure to coastal flooding
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000716 ! has exposure stimulus storm surge process
relationship: RO:0002309 ENVO:01000716 ! has exposure stimulus storm surge process

[Term]
id: ECTO:8000029
name: exposure to areal flooding
def: "A exposure event involving the interaction of an exposure receptor to areal flooding." []
synonym: "areal flooding exposure" EXACT []
is_a: ECTO:8000016 ! exposure to flooding
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000717 ! has exposure stimulus areal flooding
relationship: RO:0002309 ENVO:01000717 ! has exposure stimulus areal flooding

[Term]
id: ECTO:8000030
name: exposure to urban flooding
def: "A exposure event involving the interaction of an exposure receptor to urban flooding." []
synonym: "urban flooding exposure" EXACT []
is_a: ECTO:8000016 ! exposure to flooding
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000718 ! has exposure stimulus urban flooding
relationship: RO:0002309 ENVO:01000718 ! has exposure stimulus urban flooding

[Term]
id: ECTO:8000031
name: exposure to carbon dioxide emission process
def: "A exposure event involving the interaction of an exposure receptor to carbon dioxide emission process." []
synonym: "carbon dioxide emission process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000769 ! has exposure stimulus carbon dioxide emission process
relationship: RO:0002309 ENVO:01000769 ! has exposure stimulus carbon dioxide emission process

[Term]
id: ECTO:8000032
name: obsolete exposure to greenhouse effect
is_obsolete: true
replaced_by: ECTO:8000005

[Term]
id: ECTO:8000033
name: exposure to accumulation of toxins from algal bloom process
def: "A exposure event involving the interaction of an exposure receptor to accumulation of toxins from algal bloom process." []
synonym: "accumulation of toxins from algal bloom process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500024 ! has exposure stimulus accumulation of toxins from algal bloom process
relationship: RO:0002309 ENVO:02500024 ! has exposure stimulus accumulation of toxins from algal bloom process

[Term]
id: ECTO:8000034
name: exposure to degradation of toxins from algal bloom process
def: "A exposure event involving the interaction of an exposure receptor to degradation of toxins from algal bloom process." []
synonym: "degradation of toxins from algal bloom process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500025 ! has exposure stimulus degradation of toxins from algal bloom process
relationship: RO:0002309 ENVO:02500025 ! has exposure stimulus degradation of toxins from algal bloom process

[Term]
id: ECTO:8000035
name: exposure to anthropogenic modulatory intervention process
def: "A exposure event involving the interaction of an exposure receptor to anthropogenic modulatory intervention process." []
synonym: "anthropogenic modulatory intervention process exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500026 ! has exposure stimulus anthropogenic modulatory intervention process
relationship: RO:0002309 ENVO:02500026 ! has exposure stimulus anthropogenic modulatory intervention process

[Term]
id: ECTO:8000036
name: exposure to air pollution
def: "A exposure event involving the interaction of an exposure receptor to air pollution." []
synonym: "air pollution exposure" EXACT []
is_a: ECTO:8000019 ! exposure to environmental pollution
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500037 ! has exposure stimulus air pollution
relationship: RO:0002309 ENVO:02500037 ! has exposure stimulus air pollution

[Term]
id: ECTO:8000037
name: exposure to soil pollution
def: "A exposure event involving the interaction of an exposure receptor to soil pollution." []
synonym: "soil pollution exposure" EXACT []
is_a: ECTO:8000019 ! exposure to environmental pollution
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500038 ! has exposure stimulus soil pollution
relationship: RO:0002309 ENVO:02500038 ! has exposure stimulus soil pollution

[Term]
id: ECTO:8000038
name: exposure to water pollution
def: "A exposure event involving the interaction of an exposure receptor to water pollution." []
synonym: "water pollution exposure" EXACT []
is_a: ECTO:8000019 ! exposure to environmental pollution
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500039 ! has exposure stimulus water pollution
relationship: RO:0002309 ENVO:02500039 ! has exposure stimulus water pollution

[Term]
id: ECTO:8000039
name: obsolete exposure to plastic pollution
is_obsolete: true
replaced_by: ECTO:8000007

[Term]
id: ECTO:8000040
name: exposure to urban pollution
def: "A exposure event involving the interaction of an exposure receptor to urban pollution." []
synonym: "urban pollution exposure" EXACT []
is_a: ECTO:8000019 ! exposure to environmental pollution
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:02500044 ! has exposure stimulus urban pollution
relationship: RO:0002309 ENVO:02500044 ! has exposure stimulus urban pollution

[Term]
id: ECTO:8000041
name: exposure to drought
def: "A exposure event involving the interaction of an exposure receptor to drought." []
synonym: "drought exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:1000745 ! has exposure stimulus drought
relationship: RO:0002309 ENVO:1000745 ! has exposure stimulus drought

[Term]
id: ECTO:8000044
name: exposure to sound radiation
def: "A exposure event involving the interaction of an exposure receptor to acoustic radiation." []
synonym: "acoustic radiation exposure" EXACT []
is_a: ECTO:0000001 ! exposure to radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001027 ! has exposure stimulus acoustic radiation
relationship: RO:0002309 ENVO:01001027 ! has exposure stimulus acoustic radiation

[Term]
id: ECTO:8000045
name: exposure to gamma radiation
def: "A exposure event involving the interaction of an exposure receptor to gamma-ray radiation." []
synonym: "gamma-ray radiation exposure" EXACT []
is_a: ECTO:7000047 ! exposure to ionizing radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001218 ! has exposure stimulus gamma-ray radiation
relationship: RO:0002309 ENVO:21001218 ! has exposure stimulus gamma-ray radiation

[Term]
id: ECTO:8000046
name: exposure to x-ray radiation
def: "A exposure event involving the interaction of an exposure receptor to X-ray radiation." []
synonym: "X-ray radiation exposure" EXACT []
is_a: ECTO:7000047 ! exposure to ionizing radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001217 ! has exposure stimulus X-ray radiation
relationship: RO:0002309 ENVO:21001217 ! has exposure stimulus X-ray radiation

[Term]
id: ECTO:8000049
name: exposure to infrared radiation
def: "A exposure event involving the interaction of an exposure receptor to infrared radiation." []
synonym: "infrared radiation exposure" EXACT []
is_a: ECTO:0000002 ! exposure to electromagnetic radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001214 ! has exposure stimulus infrared radiation
relationship: RO:0002309 ENVO:21001214 ! has exposure stimulus infrared radiation

[Term]
id: ECTO:8000050
name: exposure to far-infrared radiation
def: "A exposure event involving the interaction of an exposure receptor to far-infrared radiation." []
synonym: "far-infrared radiation exposure" EXACT []
is_a: ECTO:8000049 ! exposure to infrared radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03500015 ! has exposure stimulus far-infrared radiation
relationship: RO:0002309 ENVO:03500015 ! has exposure stimulus far-infrared radiation

[Term]
id: ECTO:8000051
name: exposure to mid-infrared radiation
def: "A exposure event involving the interaction of an exposure receptor to mid-infrared radiation." []
synonym: "mid-infrared radiation exposure" EXACT []
is_a: ECTO:8000049 ! exposure to infrared radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03500013 ! has exposure stimulus mid-infrared radiation
relationship: RO:0002309 ENVO:03500013 ! has exposure stimulus mid-infrared radiation

[Term]
id: ECTO:8000052
name: exposure to near-infrared radiation
def: "A exposure event involving the interaction of an exposure receptor to near-infrared radiation." []
synonym: "near-infrared radiation exposure" EXACT []
is_a: ECTO:8000049 ! exposure to infrared radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03500014 ! has exposure stimulus near-infrared radiation
relationship: RO:0002309 ENVO:03500014 ! has exposure stimulus near-infrared radiation

[Term]
id: ECTO:8000053
name: exposure to microwave radiation
def: "A exposure event involving the interaction of an exposure receptor to microwave radiation." []
synonym: "microwave radiation exposure" EXACT []
is_a: ECTO:0000002 ! exposure to electromagnetic radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001212 ! has exposure stimulus microwave radiation
relationship: RO:0002309 ENVO:21001212 ! has exposure stimulus microwave radiation

[Term]
id: ECTO:8000054
name: exposure to radiowave radiation
def: "A exposure event involving the interaction of an exposure receptor to radio wave radiation." []
synonym: "radio wave radiation exposure" EXACT []
is_a: ECTO:0000002 ! exposure to electromagnetic radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:21001213 ! has exposure stimulus radio wave radiation
relationship: RO:0002309 ENVO:21001213 ! has exposure stimulus radio wave radiation

[Term]
id: ECTO:8000055
name: exposure to ultrasound radiation
def: "A exposure event involving the interaction of an exposure receptor to ultrasound radiation." []
synonym: "ultrasound radiation exposure" EXACT []
is_a: ECTO:8000044 ! exposure to sound radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03500012 ! has exposure stimulus ultrasound radiation
relationship: RO:0002309 ENVO:03500012 ! has exposure stimulus ultrasound radiation

[Term]
id: ECTO:8000056
name: exposure to infrasound
def: "A exposure event involving the interaction of an exposure receptor to infrasound." []
synonym: "infrasound exposure" EXACT []
is_a: ECTO:8000044 ! exposure to sound radiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001566 ! has exposure stimulus infrasound
relationship: RO:0002309 ENVO:01001566 ! has exposure stimulus infrasound

[Term]
id: ECTO:8000057
name: exposure to fire
def: "A exposure event involving the interaction of an exposure receptor to fire." []
synonym: "fire exposure" EXACT []
is_a: ECTO:8000006 ! exposure to combusion process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01000786 ! has exposure stimulus fire
relationship: RO:0002309 ENVO:01000786 ! has exposure stimulus fire

[Term]
id: ECTO:8000058
name: exposure to cyclone
def: "A exposure event involving the interaction of an exposure receptor to cyclone." []
synonym: "cyclone exposure" EXACT []
is_a: ECTO:8000017 ! exposure to atmospheric process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001297 ! has exposure stimulus cyclone
relationship: RO:0002309 ENVO:01001297 ! has exposure stimulus cyclone

[Term]
id: ECTO:8000059
name: exposure to acidic water-based rain
def: "A exposure event involving the interaction of an exposure receptor to acidic water-based rain." []
synonym: "acidic water-based rain exposure" EXACT []
is_a: ECTO:1000027 ! exposure to rain
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:03000128 ! has exposure stimulus acidic water-based rain
relationship: RO:0002309 ENVO:03000128 ! has exposure stimulus acidic water-based rain

[Term]
id: ECTO:8000060
name: exposure to vibration
def: "A exposure event involving the interaction of an exposure receptor to vibration process." []
synonym: "vibration process exposure" EXACT []
is_a: ECTO:8000000 ! exposure to environmental process
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001759 ! has exposure stimulus vibration process
relationship: RO:0002309 ENVO:01001759 ! has exposure stimulus vibration process

[Term]
id: ECTO:8000061
name: exposure to Solar radiation
def: "A exposure event involving the interaction of an exposure receptor to Solar radiation." []
synonym: "Solar radiation exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01001862 ! has exposure stimulus Solar radiation
relationship: RO:0002309 ENVO:01001862 ! has exposure stimulus Solar radiation

[Term]
id: ECTO:8000062
name: exposure to irradiation by ionizing radiation
def: "A exposure event involving the interaction of an exposure receptor to irradiation by ionizing radiation." []
synonym: "irradiation by ionizing radiation exposure" EXACT []
is_a: ECTO:1000045 ! exposure to irradiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01003015 ! has exposure stimulus irradiation by ionizing radiation
relationship: RO:0002309 ENVO:01003015 ! has exposure stimulus irradiation by ionizing radiation

[Term]
id: ECTO:8000063
name: exposure to irradiation by photosynthetically active radiation
def: "A exposure event involving the interaction of an exposure receptor to irradiation by photosynthetically active radiation." []
synonym: "irradiation by photosynthetically active radiation exposure" EXACT []
is_a: ECTO:1000045 ! exposure to irradiation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 ENVO:01003017 ! has exposure stimulus irradiation by photosynthetically active radiation
relationship: RO:0002309 ENVO:01003017 ! has exposure stimulus irradiation by photosynthetically active radiation

[Term]
id: ECTO:9000001
name: exposure to amlodipine
def: "An exposure to amlodipine." []
synonym: "amlodipine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2668 ! has exposure stimulus amlodipine
relationship: RO:0002309 CHEBI:2668 ! has exposure stimulus amlodipine

[Term]
id: ECTO:9000002
name: exposure to biguanide
def: "An exposure to biguanide." []
synonym: "biguanide exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3095 ! has exposure stimulus biguanide
relationship: RO:0002309 CHEBI:3095 ! has exposure stimulus biguanide

[Term]
id: ECTO:9000003
name: exposure to digitalin
def: "An exposure to digitalin." []
synonym: "digitalin exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000436 ! exposure to glycoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28143 ! has exposure stimulus digitalin
relationship: RO:0002309 CHEBI:28143 ! has exposure stimulus digitalin

[Term]
id: ECTO:9000004
name: exposure to nitroglycerin
def: "An exposure to nitroglycerin." []
synonym: "nitroglycerin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28787 ! has exposure stimulus nitroglycerin
relationship: RO:0002309 CHEBI:28787 ! has exposure stimulus nitroglycerin

[Term]
id: ECTO:9000006
name: exposure to premarin
def: "An exposure to estrone sodium sulfate." []
synonym: "estrone sodium sulfate exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8389 ! has exposure stimulus estrone sodium sulfate
relationship: RO:0002309 CHEBI:8389 ! has exposure stimulus estrone sodium sulfate

[Term]
id: ECTO:9000007
name: exposure to probucol
def: "An exposure to probucol." []
synonym: "probucol exposure" EXACT []
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8427 ! has exposure stimulus probucol
relationship: RO:0002309 CHEBI:8427 ! has exposure stimulus probucol

[Term]
id: ECTO:9000008
name: exposure to aspirin
def: "An exposure to acetylsalicylic acid." []
synonym: "acetylsalicylic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15365 ! has exposure stimulus acetylsalicylic acid
relationship: RO:0002309 CHEBI:15365 ! has exposure stimulus acetylsalicylic acid

[Term]
id: ECTO:9000009
name: exposure to diltiazem
def: "An exposure to diltiazem." []
synonym: "diltiazem exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:101278 ! has exposure stimulus diltiazem
relationship: RO:0002309 CHEBI:101278 ! has exposure stimulus diltiazem

[Term]
id: ECTO:9000010
name: exposure to estrogens
def: "An exposure to estrogen." []
synonym: "estrogen exposure" EXACT []
is_a: ECTO:9002127 ! exposure to sex hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50114 ! has exposure stimulus estrogen
relationship: RO:0002309 CHEBI:50114 ! has exposure stimulus estrogen

[Term]
id: ECTO:9000011
name: exposure to heparin
def: "An exposure to heparin." []
synonym: "heparin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28304 ! has exposure stimulus heparin
relationship: RO:0002309 CHEBI:28304 ! has exposure stimulus heparin

[Term]
id: ECTO:9000012
name: exposure to nifedipine
def: "An exposure to nifedipine." []
synonym: "nifedipine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7565 ! has exposure stimulus nifedipine
relationship: RO:0002309 CHEBI:7565 ! has exposure stimulus nifedipine

[Term]
id: ECTO:9000013
name: exposure to thiazolidinediones
def: "An exposure to thiazolidinediones." []
synonym: "thiazolidinediones exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50990 ! has exposure stimulus thiazolidinediones
relationship: RO:0002309 CHEBI:50990 ! has exposure stimulus thiazolidinediones

[Term]
id: ECTO:9000014
name: exposure to verapamil
def: "An exposure to verapamil." []
synonym: "verapamil exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9948 ! has exposure stimulus verapamil
relationship: RO:0002309 CHEBI:9948 ! has exposure stimulus verapamil

[Term]
id: ECTO:9000016
name: exposure to hydrogen chloride
def: "An exposure to hydrogen chloride." []
synonym: "hydrogen chloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17883 ! has exposure stimulus hydrogen chloride
relationship: RO:0002309 CHEBI:17883 ! has exposure stimulus hydrogen chloride

[Term]
id: ECTO:9000017
name: exposure to sulfuric acid
def: "An exposure to sulfuric acid." []
synonym: "sulfuric acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26836 ! has exposure stimulus sulfuric acid
relationship: RO:0002309 CHEBI:26836 ! has exposure stimulus sulfuric acid

[Term]
id: ECTO:9000018
name: exposure to phosphoric acid
def: "An exposure to phosphoric acid." []
synonym: "phosphoric acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26078 ! has exposure stimulus phosphoric acid
relationship: RO:0002309 CHEBI:26078 ! has exposure stimulus phosphoric acid

[Term]
id: ECTO:9000019
name: exposure to acetic acid
def: "An exposure to acetic acid." []
synonym: "acetic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15366 ! has exposure stimulus acetic acid
relationship: RO:0002309 CHEBI:15366 ! has exposure stimulus acetic acid

[Term]
id: ECTO:9000020
name: exposure to nitric acid
def: "An exposure to nitric acid." []
synonym: "nitric acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48107 ! has exposure stimulus nitric acid
relationship: RO:0002309 CHEBI:48107 ! has exposure stimulus nitric acid

[Term]
id: ECTO:9000021
name: exposure to alkali metal salt
def: "An exposure to alkali metal salt." []
synonym: "alkali metal salt exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35479 ! has exposure stimulus alkali metal salt
relationship: RO:0002309 CHEBI:35479 ! has exposure stimulus alkali metal salt

[Term]
id: ECTO:9000022
name: exposure to sodium hydroxide
def: "An exposure to sodium hydroxide." []
synonym: "sodium hydroxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32145 ! has exposure stimulus sodium hydroxide
relationship: RO:0002309 CHEBI:32145 ! has exposure stimulus sodium hydroxide

[Term]
id: ECTO:9000023
name: exposure to magnesium hydroxide
def: "An exposure to magnesium hydroxide." []
synonym: "magnesium hydroxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35149 ! has exposure stimulus magnesium hydroxide
relationship: RO:0002309 CHEBI:35149 ! has exposure stimulus magnesium hydroxide

[Term]
id: ECTO:9000024
name: exposure to calcium hydroxide
def: "An exposure to calcium hydroxide." []
synonym: "calcium hydroxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35150 ! has exposure stimulus calcium hydroxide
relationship: RO:0002309 CHEBI:35150 ! has exposure stimulus calcium hydroxide

[Term]
id: ECTO:9000025
name: exposure to potassium hydroxide
def: "An exposure to potassium hydroxide." []
synonym: "potassium hydroxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32035 ! has exposure stimulus potassium hydroxide
relationship: RO:0002309 CHEBI:32035 ! has exposure stimulus potassium hydroxide

[Term]
id: ECTO:9000026
name: exposure to alcohol
def: "An exposure to alcohol." []
synonym: "alcohol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30879 ! has exposure stimulus alcohol
relationship: RO:0002309 CHEBI:30879 ! has exposure stimulus alcohol

[Term]
id: ECTO:9000027
name: exposure to ethanol
def: "An exposure to ethanol." []
synonym: "ethanol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16236 ! has exposure stimulus ethanol
relationship: RO:0002309 CHEBI:16236 ! has exposure stimulus ethanol

[Term]
id: ECTO:9000028
name: exposure to methanol
def: "An exposure to methanol." []
synonym: "methanol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17790 ! has exposure stimulus methanol
relationship: RO:0002309 CHEBI:17790 ! has exposure stimulus methanol

[Term]
id: ECTO:9000029
name: exposure to aluminum
def: "An exposure to aluminium molecular entity." []
synonym: "aluminium molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33620 ! has exposure stimulus aluminium molecular entity
relationship: RO:0002309 CHEBI:33620 ! has exposure stimulus aluminium molecular entity

[Term]
id: ECTO:9000030
name: exposure to aluminum oxides
def: "An exposure to aluminium oxides." []
synonym: "aluminium oxides exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000029 ! exposure to aluminum
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33623 ! has exposure stimulus aluminium oxides
relationship: RO:0002309 CHEBI:33623 ! has exposure stimulus aluminium oxides

[Term]
id: ECTO:9000031
name: exposure to ammonia
def: "An exposure to ammonia." []
synonym: "ammonia exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16134 ! has exposure stimulus ammonia
relationship: RO:0002309 CHEBI:16134 ! has exposure stimulus ammonia

[Term]
id: ECTO:9000032
name: exposure to arsenic
def: "An exposure to arsenic molecular entity." []
synonym: "arsenic molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22632 ! has exposure stimulus arsenic molecular entity
relationship: RO:0002309 CHEBI:22632 ! has exposure stimulus arsenic molecular entity

[Term]
id: ECTO:9000033
name: exposure to asbestos
def: "An exposure to asbestos." []
synonym: "asbestos exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46661 ! has exposure stimulus asbestos
relationship: RO:0002309 CHEBI:46661 ! has exposure stimulus asbestos

[Term]
id: ECTO:9000034
name: exposure to benzene
def: "An exposure to benzene." []
synonym: "benzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16716 ! has exposure stimulus benzene
relationship: RO:0002309 CHEBI:16716 ! has exposure stimulus benzene

[Term]
id: ECTO:9000035
name: exposure to xylene
def: "An exposure to xylene." []
synonym: "xylene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27338 ! has exposure stimulus xylene
relationship: RO:0002309 CHEBI:27338 ! has exposure stimulus xylene

[Term]
id: ECTO:9000036
name: exposure to toluene
def: "An exposure to toluene." []
synonym: "toluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17578 ! has exposure stimulus toluene
relationship: RO:0002309 CHEBI:17578 ! has exposure stimulus toluene

[Term]
id: ECTO:9000037
name: exposure to chromium
def: "An exposure to chromium molecular entity." []
synonym: "chromium molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23237 ! has exposure stimulus chromium molecular entity
relationship: RO:0002309 CHEBI:23237 ! has exposure stimulus chromium molecular entity

[Term]
id: ECTO:9000038
name: exposure to chromate(2-)
def: "An exposure to chromate(2-)." []
synonym: "chromate(2-) exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000037 ! exposure to chromium
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35404 ! has exposure stimulus chromate(2-)
relationship: RO:0002309 CHEBI:35404 ! has exposure stimulus chromate(2-)

[Term]
id: ECTO:9000039
name: exposure to 1,2-dichloroethane
def: "An exposure to 1,2-dichloroethane." []
synonym: "1,2-dichloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27789 ! has exposure stimulus 1,2-dichloroethane
relationship: RO:0002309 CHEBI:27789 ! has exposure stimulus 1,2-dichloroethane

[Term]
id: ECTO:9000042
name: exposure to chloroform
def: "An exposure to chloroform." []
synonym: "chloroform exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35255 ! has exposure stimulus chloroform
relationship: RO:0002309 CHEBI:35255 ! has exposure stimulus chloroform

[Term]
id: ECTO:9000043
name: exposure to chloroprene
def: "An exposure to chloroprene." []
synonym: "chloroprene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39481 ! has exposure stimulus chloroprene
relationship: RO:0002309 CHEBI:39481 ! has exposure stimulus chloroprene

[Term]
id: ECTO:9000044
name: exposure to ketone
def: "An exposure to ketone." []
synonym: "ketone exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17087 ! has exposure stimulus ketone
relationship: RO:0002309 CHEBI:17087 ! has exposure stimulus ketone

[Term]
id: ECTO:9000045
name: exposure to dichloromethane
def: "An exposure to dichloromethane." []
synonym: "dichloromethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15767 ! has exposure stimulus dichloromethane
relationship: RO:0002309 CHEBI:15767 ! has exposure stimulus dichloromethane

[Term]
id: ECTO:9000048
name: exposure to tetrachloromethane
def: "An exposure to tetrachloromethane." []
synonym: "exposure to carbon tetrachloride" EXACT []
synonym: "tetrachloromethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27385 ! has exposure stimulus tetrachloromethane
relationship: RO:0002309 CHEBI:27385 ! has exposure stimulus tetrachloromethane

[Term]
id: ECTO:9000049
name: exposure to carbon dioxide
def: "An exposure to carbon dioxide." []
synonym: "carbon dioxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16526 ! has exposure stimulus carbon dioxide
relationship: RO:0002309 CHEBI:16526 ! has exposure stimulus carbon dioxide

[Term]
id: ECTO:9000051
name: exposure to dinitrogen oxide
def: "An exposure to dinitrogen oxide." []
synonym: "dinitrogen oxide exposure" EXACT []
synonym: "exposure to nitrous oxide" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17045 ! has exposure stimulus dinitrogen oxide
relationship: RO:0002309 CHEBI:17045 ! has exposure stimulus dinitrogen oxide

[Term]
id: ECTO:9000052
name: exposure to ozone
def: "An exposure to ozone." []
synonym: "ozone exposure" EXACT []
is_a: ECTO:9000150 ! exposure to reactive oxygen species
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
is_a: ECTO:9002338 ! exposure to nucleotide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25812 ! has exposure stimulus ozone
relationship: RO:0002309 CHEBI:25812 ! has exposure stimulus ozone

[Term]
id: ECTO:9000055
name: exposure to talc
def: "An exposure to Talc." []
synonym: "Talc exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32178 ! has exposure stimulus Talc
relationship: RO:0002309 CHEBI:32178 ! has exposure stimulus Talc

[Term]
id: ECTO:9000056
name: exposure to biphenyls
def: "An exposure to biphenyls." []
synonym: "biphenyls exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22888 ! has exposure stimulus biphenyls
relationship: RO:0002309 CHEBI:22888 ! has exposure stimulus biphenyls

[Term]
id: ECTO:9000057
name: exposure to bisphenol A
def: "An exposure to bisphenol A." []
synonym: "bisphenol A exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33216 ! has exposure stimulus bisphenol A
relationship: RO:0002309 CHEBI:33216 ! has exposure stimulus bisphenol A

[Term]
id: ECTO:9000058
name: exposure to dichlorobenzene
def: "An exposure to dichlorobenzene." []
synonym: "dichlorobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23697 ! has exposure stimulus dichlorobenzene
relationship: RO:0002309 CHEBI:23697 ! has exposure stimulus dichlorobenzene

[Term]
id: ECTO:9000059
name: exposure to ethylbenzene
def: "An exposure to ethylbenzene." []
synonym: "ethylbenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16101 ! has exposure stimulus ethylbenzene
relationship: RO:0002309 CHEBI:16101 ! has exposure stimulus ethylbenzene

[Term]
id: ECTO:9000060
name: exposure to 1,2-dibromoethane
def: "An exposure to 1,2-dibromoethane." []
synonym: "1,2-dibromoethane exposure" EXACT []
synonym: "exposure to ethyl dibromide" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28534 ! has exposure stimulus 1,2-dibromoethane
relationship: RO:0002309 CHEBI:28534 ! has exposure stimulus 1,2-dibromoethane

[Term]
id: ECTO:9000062
name: exposure to coal-tar pitch
def: "An exposure to Coal-tar pitch." []
synonym: "Coal-tar pitch exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80501 ! has exposure stimulus Coal-tar pitch
relationship: RO:0002309 CHEBI:80501 ! has exposure stimulus Coal-tar pitch

[Term]
id: ECTO:9000063
name: exposure to nickel
def: "An exposure to nickel molecular entity." []
synonym: "nickel molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33748 ! has exposure stimulus nickel molecular entity
relationship: RO:0002309 CHEBI:33748 ! has exposure stimulus nickel molecular entity

[Term]
id: ECTO:9000064
name: exposure to chloroethane
def: "An exposure to chloroethane." []
synonym: "chloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47554 ! has exposure stimulus chloroethane
relationship: RO:0002309 CHEBI:47554 ! has exposure stimulus chloroethane

[Term]
id: ECTO:9000065
name: exposure to 2-methoxyethanol
def: "An exposure to 2-methoxyethanol." []
synonym: "2-methoxyethanol exposure" EXACT []
is_a: ECTO:9002161 ! exposure to glycol ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46790 ! has exposure stimulus 2-methoxyethanol
relationship: RO:0002309 CHEBI:46790 ! has exposure stimulus 2-methoxyethanol

[Term]
id: ECTO:9000066
name: exposure to 2-ethoxyethanol
def: "An exposure to 2-ethoxyethanol." []
synonym: "2-ethoxyethanol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002161 ! exposure to glycol ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46788 ! has exposure stimulus 2-ethoxyethanol
relationship: RO:0002309 CHEBI:46788 ! has exposure stimulus 2-ethoxyethanol

[Term]
id: ECTO:9000067
name: exposure to 2-butoxyethanol
def: "An exposure to 2-butoxyethanol." []
synonym: "2-butoxyethanol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002161 ! exposure to glycol ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63921 ! has exposure stimulus 2-butoxyethanol
relationship: RO:0002309 CHEBI:63921 ! has exposure stimulus 2-butoxyethanol

[Term]
id: ECTO:9000068
name: exposure to polychlorobiphenyl
def: "An exposure to polychlorobiphenyl." []
synonym: "exposure to polychlorinated biphenyl" EXACT []
synonym: "polychlorobiphenyl exposure" EXACT []
is_a: ECTO:9001537 ! exposure to polychlorinated dibenzodioxines and related compounds
is_a: ECTO:9002155 ! exposure to chlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53156 ! has exposure stimulus polychlorobiphenyl
relationship: RO:0002309 CHEBI:53156 ! has exposure stimulus polychlorobiphenyl

[Term]
id: ECTO:9000069
name: exposure to styrene
def: "An exposure to styrene." []
synonym: "styrene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27452 ! has exposure stimulus styrene
relationship: RO:0002309 CHEBI:27452 ! has exposure stimulus styrene

[Term]
id: ECTO:9000070
name: exposure to phosgene
def: "An exposure to phosgene." []
synonym: "phosgene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29365 ! has exposure stimulus phosgene
relationship: RO:0002309 CHEBI:29365 ! has exposure stimulus phosgene

[Term]
id: ECTO:9000071
name: exposure to phenol
def: "An exposure to phenol." []
synonym: "phenol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15882 ! has exposure stimulus phenol
relationship: RO:0002309 CHEBI:15882 ! has exposure stimulus phenol

[Term]
id: ECTO:9000073
name: exposure to silicon dioxide
def: "An exposure to silicon dioxide." []
synonym: "silicon dioxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30563 ! has exposure stimulus silicon dioxide
relationship: RO:0002309 CHEBI:30563 ! has exposure stimulus silicon dioxide

[Term]
id: ECTO:9000074
name: exposure to tetrachloroethene
def: "An exposure to tetrachloroethene." []
synonym: "exposure to perchloroethylene" EXACT []
synonym: "tetrachloroethene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17300 ! has exposure stimulus tetrachloroethene
relationship: RO:0002309 CHEBI:17300 ! has exposure stimulus tetrachloroethene

[Term]
id: ECTO:9000075
name: obsolete trichloroethene exposure
is_obsolete: true
replaced_by: ECTO:9000530

[Term]
id: ECTO:9000076
name: exposure to sodium hypochlorite
def: "An exposure to sodium hypochlorite." []
synonym: "exposure to chlorine bleach" EXACT []
synonym: "sodium hypochlorite exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32146 ! has exposure stimulus sodium hypochlorite
relationship: RO:0002309 CHEBI:32146 ! has exposure stimulus sodium hypochlorite

[Term]
id: ECTO:9000077
name: exposure to chlorine
def: "An exposure to chlorine molecular entity." []
synonym: "chlorine molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23117 ! has exposure stimulus chlorine molecular entity
relationship: RO:0002309 CHEBI:23117 ! has exposure stimulus chlorine molecular entity

[Term]
id: ECTO:9000078
name: exposure to triclosan
def: "An exposure to triclosan." []
synonym: "triclosan exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:164200 ! has exposure stimulus triclosan
relationship: RO:0002309 CHEBI:164200 ! has exposure stimulus triclosan

[Term]
id: ECTO:9000079
name: exposure to polyvinyl acetate
def: "An exposure to poly(vinyl acetate)." []
synonym: "exposure to white glue" EXACT []
synonym: "exposure to wood glue" EXACT []
synonym: "poly(vinyl acetate) exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32028 ! has exposure stimulus poly(vinyl acetate)
relationship: RO:0002309 CHEBI:32028 ! has exposure stimulus poly(vinyl acetate)

[Term]
id: ECTO:9000081
name: exposure to urethane
def: "An exposure to urethane." []
synonym: "urethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17967 ! has exposure stimulus urethane
relationship: RO:0002309 CHEBI:17967 ! has exposure stimulus urethane

[Term]
id: ECTO:9000082
name: exposure to polyurethane polymer
def: "An exposure to polyurethane polymer." []
synonym: "polyurethane polymer exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60737 ! has exposure stimulus polyurethane polymer
relationship: RO:0002309 CHEBI:60737 ! has exposure stimulus polyurethane polymer

[Term]
id: ECTO:9000083
name: exposure to butanone
def: "An exposure to butanone." []
synonym: "butanone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22951 ! has exposure stimulus butanone
relationship: RO:0002309 CHEBI:22951 ! has exposure stimulus butanone

[Term]
id: ECTO:9000084
name: exposure to iodine
def: "An exposure to iodine molecular entity." []
synonym: "iodine molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24860 ! has exposure stimulus iodine molecular entity
relationship: RO:0002309 CHEBI:24860 ! has exposure stimulus iodine molecular entity

[Term]
id: ECTO:9000085
name: exposure to acetone
def: "An exposure to acetone." []
synonym: "acetone exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15347 ! has exposure stimulus acetone
relationship: RO:0002309 CHEBI:15347 ! has exposure stimulus acetone

[Term]
id: ECTO:9000087
name: exposure to iron
def: "An exposure to iron molecular entity." []
synonym: "iron molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24873 ! has exposure stimulus iron molecular entity
relationship: RO:0002309 CHEBI:24873 ! has exposure stimulus iron molecular entity

[Term]
id: ECTO:9000089
name: exposure to insecticide
def: "An exposure to insecticide." []
synonym: "insecticide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24852 ! has exposure stimulus insecticide
relationship: RO:0002309 CHEBI:24852 ! has exposure stimulus insecticide

[Term]
id: ECTO:9000090
name: exposure to rodenticide
def: "An exposure to rodenticide." []
synonym: "rodenticide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33288 ! has exposure stimulus rodenticide
relationship: RO:0002309 CHEBI:33288 ! has exposure stimulus rodenticide

[Term]
id: ECTO:9000091
name: exposure to fertilizer
def: "An exposure to fertilizer." []
synonym: "fertilizer exposure" EXACT []
is_a: ECTO:9001696 ! exposure to agrochemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33287 ! has exposure stimulus fertilizer
relationship: RO:0002309 CHEBI:33287 ! has exposure stimulus fertilizer

[Term]
id: ECTO:9000092
name: exposure to fungicide
def: "An exposure to fungicide." []
synonym: "fungicide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
is_a: ECTO:9001749 ! exposure to antifungal agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24127 ! has exposure stimulus fungicide
relationship: RO:0002309 CHEBI:24127 ! has exposure stimulus fungicide

[Term]
id: ECTO:9000094
name: exposure to perfluorooctane-1-sulfonic acid
def: "An exposure to perfluorooctane-1-sulfonic acid." []
synonym: "perfluorooctane-1-sulfonic acid exposure" EXACT []
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39421 ! has exposure stimulus perfluorooctane-1-sulfonic acid
relationship: RO:0002309 CHEBI:39421 ! has exposure stimulus perfluorooctane-1-sulfonic acid

[Term]
id: ECTO:9000095
name: exposure to perfluorooctanoic acid
def: "An exposure to perfluorooctanoic acid." []
synonym: "perfluorooctanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35549 ! has exposure stimulus perfluorooctanoic acid
relationship: RO:0002309 CHEBI:35549 ! has exposure stimulus perfluorooctanoic acid

[Term]
id: ECTO:9000096
name: exposure to methyl tert-butyl ether
def: "An exposure to methyl tert-butyl ether." []
synonym: "methyl tert-butyl ether exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27642 ! has exposure stimulus methyl tert-butyl ether
relationship: RO:0002309 CHEBI:27642 ! has exposure stimulus methyl tert-butyl ether

[Term]
id: ECTO:9000097
name: exposure to radon
def: "An exposure to radon molecular entity." []
synonym: "radon molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36911 ! has exposure stimulus radon molecular entity
relationship: RO:0002309 CHEBI:36911 ! has exposure stimulus radon molecular entity

[Term]
id: ECTO:9000098
name: exposure to methyl bromide
def: "An exposure to bromomethane." []
synonym: "bromomethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39275 ! has exposure stimulus bromomethane
relationship: RO:0002309 CHEBI:39275 ! has exposure stimulus bromomethane

[Term]
id: ECTO:9000099
name: exposure to propan-2-ol
def: "An exposure to propan-2-ol." []
synonym: "exposure to isopropanol" EXACT []
synonym: "exposure to isopropyl alcohol" EXACT []
synonym: "exposure to rubbing alcohol" EXACT []
synonym: "propan-2-ol exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17824 ! has exposure stimulus propan-2-ol
relationship: RO:0002309 CHEBI:17824 ! has exposure stimulus propan-2-ol

[Term]
id: ECTO:9000100
name: exposure to butan-1-ol
def: "An exposure to butan-1-ol." []
synonym: "butan-1-ol exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28885 ! has exposure stimulus butan-1-ol
relationship: RO:0002309 CHEBI:28885 ! has exposure stimulus butan-1-ol

[Term]
id: ECTO:9000101
name: exposure to toluene meta-diisocyanate
def: "An exposure to toluene meta-diisocyanate." []
synonym: "toluene meta-diisocyanate exposure" EXACT []
is_a: ECTO:9001309 ! exposure to diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53555 ! has exposure stimulus toluene meta-diisocyanate
relationship: RO:0002309 CHEBI:53555 ! has exposure stimulus toluene meta-diisocyanate

[Term]
id: ECTO:9000102
name: exposure to toluene 2,6-diisocyanate
def: "An exposure to toluene 2,6-diisocyanate." []
synonym: "toluene 2,6-diisocyanate exposure" EXACT []
is_a: ECTO:9000101 ! exposure to toluene meta-diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53557 ! has exposure stimulus toluene 2,6-diisocyanate
relationship: RO:0002309 CHEBI:53557 ! has exposure stimulus toluene 2,6-diisocyanate

[Term]
id: ECTO:9000103
name: exposure to toluene 2,4-diisocyanate
def: "An exposure to toluene 2,4-diisocyanate." []
synonym: "toluene 2,4-diisocyanate exposure" EXACT []
is_a: ECTO:9000101 ! exposure to toluene meta-diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53556 ! has exposure stimulus toluene 2,4-diisocyanate
relationship: RO:0002309 CHEBI:53556 ! has exposure stimulus toluene 2,4-diisocyanate

[Term]
id: ECTO:9000104
name: exposure to diphenylmethane-4,4'-diisocyanate
def: "An exposure to diphenylmethane-4,4'-diisocyanate." []
synonym: "diphenylmethane-4,4'-diisocyanate exposure" EXACT []
is_a: ECTO:9001309 ! exposure to diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53218 ! has exposure stimulus diphenylmethane-4,4'-diisocyanate
relationship: RO:0002309 CHEBI:53218 ! has exposure stimulus diphenylmethane-4,4'-diisocyanate

[Term]
id: ECTO:9000105
name: exposure to uranium
def: "An exposure to uranium molecular entity." []
synonym: "uranium molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33499 ! has exposure stimulus uranium molecular entity
relationship: RO:0002309 CHEBI:33499 ! has exposure stimulus uranium molecular entity

[Term]
id: ECTO:9000106
name: exposure to polymer
def: "An exposure to polymer." []
synonym: "polymer exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60027 ! has exposure stimulus polymer
relationship: RO:0002309 CHEBI:60027 ! has exposure stimulus polymer

[Term]
id: ECTO:9000107
name: exposure to solvent
def: "An exposure to solvent." []
synonym: "solvent exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46787 ! has exposure stimulus solvent
relationship: RO:0002309 CHEBI:46787 ! has exposure stimulus solvent

[Term]
id: ECTO:9000108
name: exposure to sodium carbonate
def: "An exposure to sodium carbonate." []
synonym: "sodium carbonate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29377 ! has exposure stimulus sodium carbonate
relationship: RO:0002309 CHEBI:29377 ! has exposure stimulus sodium carbonate

[Term]
id: ECTO:9000109
name: exposure to sodium silicate
def: "An exposure to sodium silicate." []
synonym: "sodium silicate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60720 ! has exposure stimulus sodium silicate
relationship: RO:0002309 CHEBI:60720 ! has exposure stimulus sodium silicate

[Term]
id: ECTO:9000110
name: exposure to EDTA(2-)
def: "An exposure to EDTA(2-)." []
synonym: "EDTA(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64755 ! has exposure stimulus EDTA(2-)
relationship: RO:0002309 CHEBI:64755 ! has exposure stimulus EDTA(2-)

[Term]
id: ECTO:9000111
name: exposure to hexane
def: "An exposure to hexane." []
synonym: "hexane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29021 ! has exposure stimulus hexane
relationship: RO:0002309 CHEBI:29021 ! has exposure stimulus hexane

[Term]
id: ECTO:9000112
name: exposure to heptane
def: "An exposure to heptane." []
synonym: "heptane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43098 ! has exposure stimulus heptane
relationship: RO:0002309 CHEBI:43098 ! has exposure stimulus heptane

[Term]
id: ECTO:9000113
name: exposure to rubber particle
def: "An exposure to rubber particle." []
synonym: "rubber particle exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28798 ! has exposure stimulus rubber particle
relationship: RO:0002309 CHEBI:28798 ! has exposure stimulus rubber particle

[Term]
id: ECTO:9000114
name: exposure to epichlorohydrin
def: "An exposure to epichlorohydrin." []
synonym: "epichlorohydrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37144 ! has exposure stimulus epichlorohydrin
relationship: RO:0002309 CHEBI:37144 ! has exposure stimulus epichlorohydrin

[Term]
id: ECTO:9000115
name: exposure to polyethylene polymer
def: "An exposure to polyethylene polymer." []
synonym: "polyethylene polymer exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60034 ! has exposure stimulus polyethylene polymer
relationship: RO:0002309 CHEBI:60034 ! has exposure stimulus polyethylene polymer

[Term]
id: ECTO:9000116
name: exposure to alpha-pinene
def: "An exposure to alpha-pinene." []
synonym: "alpha-pinene exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36740 ! has exposure stimulus alpha-pinene
relationship: RO:0002309 CHEBI:36740 ! has exposure stimulus alpha-pinene

[Term]
id: ECTO:9000117
name: exposure to beta-pinene
def: "An exposure to beta-pinene." []
synonym: "beta-pinene exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50025 ! has exposure stimulus beta-pinene
relationship: RO:0002309 CHEBI:50025 ! has exposure stimulus beta-pinene

[Term]
id: ECTO:9000118
name: exposure to citronellol
def: "An exposure to citronellol." []
synonym: "citronellol exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50462 ! has exposure stimulus citronellol
relationship: RO:0002309 CHEBI:50462 ! has exposure stimulus citronellol

[Term]
id: ECTO:9000119
name: exposure to citronellal
def: "An exposure to citronellal." []
synonym: "citronellal exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47856 ! has exposure stimulus citronellal
relationship: RO:0002309 CHEBI:47856 ! has exposure stimulus citronellal

[Term]
id: ECTO:9000120
name: exposure to geraniol
def: "An exposure to geraniol." []
synonym: "geraniol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17447 ! has exposure stimulus geraniol
relationship: RO:0002309 CHEBI:17447 ! has exposure stimulus geraniol

[Term]
id: ECTO:9000121
name: exposure to N,N-diethyl-m-toluamide
def: "An exposure to N,N-diethyl-m-toluamide." []
synonym: "N,N-diethyl-m-toluamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7071 ! has exposure stimulus N,N-diethyl-m-toluamide
relationship: RO:0002309 CHEBI:7071 ! has exposure stimulus N,N-diethyl-m-toluamide

[Term]
id: ECTO:9000122
name: exposure to cyfluthrin
def: "An exposure to cyfluthrin." []
synonym: "cyfluthrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4034 ! has exposure stimulus cyfluthrin
relationship: RO:0002309 CHEBI:4034 ! has exposure stimulus cyfluthrin

[Term]
id: ECTO:9000123
name: exposure to folic acid
def: "An exposure to folic acid." []
synonym: "folic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27470 ! has exposure stimulus folic acid
relationship: RO:0002309 CHEBI:27470 ! has exposure stimulus folic acid

[Term]
id: ECTO:9000124
name: exposure to 5-methyltetrahydrofolate
def: "An exposure to 5-methyltetrahydrofolate." []
synonym: "5-methyltetrahydrofolate exposure" EXACT []
is_a: ECTO:9000476 ! exposure to tetrahydrofolate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:20612 ! has exposure stimulus 5-methyltetrahydrofolate
relationship: RO:0002309 CHEBI:20612 ! has exposure stimulus 5-methyltetrahydrofolate

[Term]
id: ECTO:9000125
name: exposure to vitamin A
def: "An exposure to vitamin A." []
synonym: "vitamin A exposure" EXACT []
is_a: ECTO:9001346 ! exposure to retinoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:12777 ! has exposure stimulus vitamin A
relationship: RO:0002309 CHEBI:12777 ! has exposure stimulus vitamin A

[Term]
id: ECTO:9000126
name: exposure to beta-carotene
def: "An exposure to beta-carotene." []
synonym: "beta-carotene exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17579 ! has exposure stimulus beta-carotene
relationship: RO:0002309 CHEBI:17579 ! has exposure stimulus beta-carotene

[Term]
id: ECTO:9000127
name: exposure to retinyl palmitate
def: "An exposure to retinyl palmitate." []
synonym: "retinyl palmitate exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15040 ! has exposure stimulus retinyl palmitate
relationship: RO:0002309 CHEBI:15040 ! has exposure stimulus retinyl palmitate

[Term]
id: ECTO:9000128
name: exposure to all-trans-retinol
def: "An exposure to all-trans-retinol." []
synonym: "all-trans-retinol exposure" EXACT []
is_a: ECTO:9000125 ! exposure to vitamin A
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17336 ! has exposure stimulus all-trans-retinol
relationship: RO:0002309 CHEBI:17336 ! has exposure stimulus all-trans-retinol

[Term]
id: ECTO:9000129
name: exposure to all-trans-retinal
def: "An exposure to all-trans-retinal." []
synonym: "all-trans-retinal exposure" EXACT []
is_a: ECTO:9000125 ! exposure to vitamin A
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17898 ! has exposure stimulus all-trans-retinal
relationship: RO:0002309 CHEBI:17898 ! has exposure stimulus all-trans-retinal

[Term]
id: ECTO:9000130
name: exposure to 11-cis-retinal
def: "An exposure to 11-cis-retinal." []
synonym: "11-cis-retinal exposure" EXACT []
is_a: ECTO:9001346 ! exposure to retinoid
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16066 ! has exposure stimulus 11-cis-retinal
relationship: RO:0002309 CHEBI:16066 ! has exposure stimulus 11-cis-retinal

[Term]
id: ECTO:9000131
name: exposure to all-trans-retinoic acid
def: "An exposure to all-trans-retinoic acid." []
synonym: "all-trans-retinoic acid exposure" EXACT []
is_a: ECTO:9000125 ! exposure to vitamin A
is_a: ECTO:9000216 ! exposure to retinoic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15367 ! has exposure stimulus all-trans-retinoic acid
relationship: RO:0002309 CHEBI:15367 ! has exposure stimulus all-trans-retinoic acid

[Term]
id: ECTO:9000132
name: exposure to 9-cis-retinoic acid
def: "An exposure to 9-cis-retinoic acid." []
synonym: "9-cis-retinoic acid exposure" EXACT []
is_a: ECTO:9000216 ! exposure to retinoic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50648 ! has exposure stimulus 9-cis-retinoic acid
relationship: RO:0002309 CHEBI:50648 ! has exposure stimulus 9-cis-retinoic acid

[Term]
id: ECTO:9000133
name: exposure to vitamin D
def: "An exposure to vitamin D." []
synonym: "vitamin D exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27300 ! has exposure stimulus vitamin D
relationship: RO:0002309 CHEBI:27300 ! has exposure stimulus vitamin D

[Term]
id: ECTO:9000134
name: exposure to vitamin D2
def: "An exposure to vitamin D2." []
synonym: "vitamin D2 exposure" EXACT []
is_a: ECTO:9000133 ! exposure to vitamin D
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28934 ! has exposure stimulus vitamin D2
relationship: RO:0002309 CHEBI:28934 ! has exposure stimulus vitamin D2

[Term]
id: ECTO:9000135
name: exposure to vitamin D3
def: "An exposure to D3 vitamins." []
synonym: "D3 vitamins exposure" EXACT []
is_a: ECTO:9000133 ! exposure to vitamin D
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73558 ! has exposure stimulus D3 vitamins
relationship: RO:0002309 CHEBI:73558 ! has exposure stimulus D3 vitamins

[Term]
id: ECTO:9000136
name: exposure to tocopherol
def: "An exposure to tocopherol." []
synonym: "tocopherol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27013 ! has exposure stimulus tocopherol
relationship: RO:0002309 CHEBI:27013 ! has exposure stimulus tocopherol

[Term]
id: ECTO:9000137
name: exposure to (+)-alpha-tocopherol
def: "An exposure to (R,R,R)-alpha-tocopherol." []
synonym: "(R,R,R)-alpha-tocopherol exposure" EXACT []
is_a: ECTO:9001341 ! exposure to alpha-tocopherol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18145 ! has exposure stimulus (R,R,R)-alpha-tocopherol
relationship: RO:0002309 CHEBI:18145 ! has exposure stimulus (R,R,R)-alpha-tocopherol

[Term]
id: ECTO:9000138
name: exposure to (-)-alpha-tocopherol
def: "An exposure to (S,S,S)-alpha-tocopherol." []
synonym: "(S,S,S)-alpha-tocopherol exposure" EXACT []
is_a: ECTO:9001341 ! exposure to alpha-tocopherol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46430 ! has exposure stimulus (S,S,S)-alpha-tocopherol
relationship: RO:0002309 CHEBI:46430 ! has exposure stimulus (S,S,S)-alpha-tocopherol

[Term]
id: ECTO:9000139
name: exposure to vitamin K
def: "An exposure to vitamin K." []
synonym: "vitamin K exposure" EXACT []
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28384 ! has exposure stimulus vitamin K
relationship: RO:0002309 CHEBI:28384 ! has exposure stimulus vitamin K

[Term]
id: ECTO:9000140
name: exposure to phylloquinone
def: "An exposure to phylloquinone." []
synonym: "phylloquinone exposure" EXACT []
is_a: ECTO:9000139 ! exposure to vitamin K
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18067 ! has exposure stimulus phylloquinone
relationship: RO:0002309 CHEBI:18067 ! has exposure stimulus phylloquinone

[Term]
id: ECTO:9000141
name: exposure to menaquinone
def: "An exposure to menaquinone." []
synonym: "menaquinone exposure" EXACT []
is_a: ECTO:9000139 ! exposure to vitamin K
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16374 ! has exposure stimulus menaquinone
relationship: RO:0002309 CHEBI:16374 ! has exposure stimulus menaquinone

[Term]
id: ECTO:9000142
name: exposure to menadione
def: "An exposure to menadione." []
synonym: "menadione exposure" EXACT []
is_a: ECTO:9000139 ! exposure to vitamin K
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28869 ! has exposure stimulus menadione
relationship: RO:0002309 CHEBI:28869 ! has exposure stimulus menadione

[Term]
id: ECTO:9000143
name: exposure to vitamin C
def: "An exposure to vitamin C." []
synonym: "vitamin C exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:176783 ! has exposure stimulus vitamin C
relationship: RO:0002309 CHEBI:176783 ! has exposure stimulus vitamin C

[Term]
id: ECTO:9000144
name: exposure to L-ascorbic acid
def: "An exposure to L-ascorbic acid." []
synonym: "L-ascorbic acid exposure" EXACT []
is_a: ECTO:9000143 ! exposure to vitamin C
is_a: ECTO:9000145 ! exposure to ascorbic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29073 ! has exposure stimulus L-ascorbic acid
relationship: RO:0002309 CHEBI:29073 ! has exposure stimulus L-ascorbic acid

[Term]
id: ECTO:9000145
name: exposure to ascorbic acid
def: "An exposure to ascorbic acid." []
synonym: "ascorbic acid exposure" EXACT []
is_a: ECTO:9000239 ! exposure to monosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22652 ! has exposure stimulus ascorbic acid
relationship: RO:0002309 CHEBI:22652 ! has exposure stimulus ascorbic acid

[Term]
id: ECTO:9000146
name: exposure to sodium ascorbate
def: "An exposure to sodium ascorbate." []
synonym: "sodium ascorbate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000143 ! exposure to vitamin C
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:113451 ! has exposure stimulus sodium ascorbate
relationship: RO:0002309 CHEBI:113451 ! has exposure stimulus sodium ascorbate

[Term]
id: ECTO:9000147
name: exposure to thiamine
def: "An exposure to vitamin B1." []
synonym: "vitamin B1 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26948 ! has exposure stimulus vitamin B1
relationship: RO:0002309 CHEBI:26948 ! has exposure stimulus vitamin B1

[Term]
id: ECTO:9000148
name: exposure to thiamine hydrochloride
def: "An exposure to thiamine hydrochloride." []
synonym: "thiamine hydrochloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000147 ! exposure to thiamine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49105 ! has exposure stimulus thiamine hydrochloride
relationship: RO:0002309 CHEBI:49105 ! has exposure stimulus thiamine hydrochloride

[Term]
id: ECTO:9000149
name: exposure to riboflavin
def: "An exposure to riboflavin." []
synonym: "riboflavin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17015 ! has exposure stimulus riboflavin
relationship: RO:0002309 CHEBI:17015 ! has exposure stimulus riboflavin

[Term]
id: ECTO:9000150
name: exposure to reactive oxygen species
def: "An exposure to reactive oxygen species." []
synonym: "reactive oxygen species exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26523 ! has exposure stimulus reactive oxygen species
relationship: RO:0002309 CHEBI:26523 ! has exposure stimulus reactive oxygen species

[Term]
id: ECTO:9000151
name: exposure to superoxide
def: "An exposure to superoxide." []
synonym: "superoxide exposure" EXACT []
is_a: ECTO:9000153 ! exposure to oxygen radical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18421 ! has exposure stimulus superoxide
relationship: RO:0002309 CHEBI:18421 ! has exposure stimulus superoxide

[Term]
id: ECTO:9000152
name: exposure to singlet dioxygen
def: "An exposure to singlet dioxygen." []
synonym: "singlet dioxygen exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000150 ! exposure to reactive oxygen species
is_a: ECTO:9000519 ! exposure to dioxygen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26689 ! has exposure stimulus singlet dioxygen
relationship: RO:0002309 CHEBI:26689 ! has exposure stimulus singlet dioxygen

[Term]
id: ECTO:9000153
name: exposure to oxygen radical
def: "An exposure to oxygen radical." []
synonym: "oxygen radical exposure" EXACT []
is_a: ECTO:9000150 ! exposure to reactive oxygen species
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61073 ! has exposure stimulus oxygen radical
relationship: RO:0002309 CHEBI:61073 ! has exposure stimulus oxygen radical

[Term]
id: ECTO:9000154
name: exposure to amphetamine
def: "An exposure to amphetamine." []
synonym: "amphetamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2679 ! has exposure stimulus amphetamine
relationship: RO:0002309 CHEBI:2679 ! has exposure stimulus amphetamine

[Term]
id: ECTO:9000155
name: exposure to lipid hydroperoxide
def: "An exposure to lipid hydroperoxide." []
synonym: "lipid hydroperoxide exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000222 ! exposure to hydroperoxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61051 ! has exposure stimulus lipid hydroperoxide
relationship: RO:0002309 CHEBI:61051 ! has exposure stimulus lipid hydroperoxide

[Term]
id: ECTO:9000156
name: exposure to water
def: "An exposure to water." []
synonym: "water exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15377 ! has exposure stimulus water
relationship: RO:0002309 CHEBI:15377 ! has exposure stimulus water

[Term]
id: ECTO:9000157
name: exposure to photon
def: "An exposure to photon." []
synonym: "photon exposure" EXACT []
is_a: ExO:0000002 ! exposure event
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30212 ! has exposure stimulus photon
relationship: RO:0002309 CHEBI:30212 ! has exposure stimulus photon

[Term]
id: ECTO:9000158
name: exposure to ethene
def: "An exposure to ethene." []
synonym: "ethene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18153 ! has exposure stimulus ethene
relationship: RO:0002309 CHEBI:18153 ! has exposure stimulus ethene

[Term]
id: ECTO:9000159
name: exposure to 2-cis-abscisic acid
def: "An exposure to 2-cis-abscisic acid." []
synonym: "2-cis-abscisic acid exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22152 ! has exposure stimulus 2-cis-abscisic acid
relationship: RO:0002309 CHEBI:22152 ! has exposure stimulus 2-cis-abscisic acid

[Term]
id: ECTO:9000160
name: exposure to gibberellin
def: "An exposure to gibberellin." []
synonym: "gibberellin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24250 ! has exposure stimulus gibberellin
relationship: RO:0002309 CHEBI:24250 ! has exposure stimulus gibberellin

[Term]
id: ECTO:9000161
name: exposure to brassinosteroid
def: "An exposure to brassinosteroid." []
synonym: "brassinosteroid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22921 ! has exposure stimulus brassinosteroid
relationship: RO:0002309 CHEBI:22921 ! has exposure stimulus brassinosteroid

[Term]
id: ECTO:9000162
name: exposure to carbohydrate
def: "An exposure to carbohydrate." []
synonym: "carbohydrate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16646 ! has exposure stimulus carbohydrate
relationship: RO:0002309 CHEBI:16646 ! has exposure stimulus carbohydrate

[Term]
id: ECTO:9000163
name: exposure to sucrose
def: "An exposure to sucrose." []
synonym: "sucrose exposure" EXACT []
is_a: ECTO:9000240 ! exposure to disaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17992 ! has exposure stimulus sucrose
relationship: RO:0002309 CHEBI:17992 ! has exposure stimulus sucrose

[Term]
id: ECTO:9000164
name: exposure to hexose
def: "An exposure to hexose." []
synonym: "hexose exposure" EXACT []
is_a: ECTO:9000239 ! exposure to monosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18133 ! has exposure stimulus hexose
relationship: RO:0002309 CHEBI:18133 ! has exposure stimulus hexose

[Term]
id: ECTO:9000165
name: exposure to glucose
def: "An exposure to glucose." []
synonym: "glucose exposure" EXACT []
is_a: ECTO:9000164 ! exposure to hexose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17234 ! has exposure stimulus glucose
relationship: RO:0002309 CHEBI:17234 ! has exposure stimulus glucose

[Term]
id: ECTO:9000166
name: exposure to fructose
def: "An exposure to fructose." []
synonym: "fructose exposure" EXACT []
is_a: ECTO:9000164 ! exposure to hexose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28757 ! has exposure stimulus fructose
relationship: RO:0002309 CHEBI:28757 ! has exposure stimulus fructose

[Term]
id: ECTO:9000167
name: exposure to salicylic acid
def: "An exposure to salicylic acid." []
synonym: "salicylic acid exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16914 ! has exposure stimulus salicylic acid
relationship: RO:0002309 CHEBI:16914 ! has exposure stimulus salicylic acid

[Term]
id: ECTO:9000168
name: exposure to jasmonic acid
def: "An exposure to jasmonic acid." []
synonym: "jasmonic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18292 ! has exposure stimulus jasmonic acid
relationship: RO:0002309 CHEBI:18292 ! has exposure stimulus jasmonic acid

[Term]
id: ECTO:9000169
name: exposure to 1-aminocyclopropanecarboxylic acid
def: "An exposure to 1-aminocyclopropanecarboxylic acid." []
synonym: "1-aminocyclopropanecarboxylic acid exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18053 ! has exposure stimulus 1-aminocyclopropanecarboxylic acid
relationship: RO:0002309 CHEBI:18053 ! has exposure stimulus 1-aminocyclopropanecarboxylic acid

[Term]
id: ECTO:9000171
name: exposure to acetate
def: "An exposure to acetate." []
synonym: "acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30089 ! has exposure stimulus acetate
relationship: RO:0002309 CHEBI:30089 ! has exposure stimulus acetate

[Term]
id: ECTO:9000172
name: exposure to inorganic compound
def: "An exposure to inorganic molecular entity." []
synonym: "inorganic molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24835 ! has exposure stimulus inorganic molecular entity
relationship: RO:0002309 CHEBI:24835 ! has exposure stimulus inorganic molecular entity

[Term]
id: ECTO:9000173
name: exposure to boron
def: "An exposure to boron molecular entity." []
synonym: "boron molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22916 ! has exposure stimulus boron molecular entity
relationship: RO:0002309 CHEBI:22916 ! has exposure stimulus boron molecular entity

[Term]
id: ECTO:9000175
name: exposure to metal cation
def: "An exposure to metal cation." []
synonym: "metal cation exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25213 ! has exposure stimulus metal cation
relationship: RO:0002309 CHEBI:25213 ! has exposure stimulus metal cation

[Term]
id: ECTO:9000176
name: exposure to iron cation
def: "An exposure to iron cation." []
synonym: "iron cation exposure" EXACT []
is_a: ECTO:9000087 ! exposure to iron
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24875 ! has exposure stimulus iron cation
relationship: RO:0002309 CHEBI:24875 ! has exposure stimulus iron cation

[Term]
id: ECTO:9000177
name: exposure to iron(2+)
def: "An exposure to iron(2+)." []
synonym: "iron(2+) exposure" EXACT []
is_a: ECTO:9000176 ! exposure to iron cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29033 ! has exposure stimulus iron(2+)
relationship: RO:0002309 CHEBI:29033 ! has exposure stimulus iron(2+)

[Term]
id: ECTO:9000178
name: exposure to iron(3+)
def: "An exposure to iron(3+)." []
synonym: "iron(3+) exposure" EXACT []
is_a: ECTO:9000176 ! exposure to iron cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29034 ! has exposure stimulus iron(3+)
relationship: RO:0002309 CHEBI:29034 ! has exposure stimulus iron(3+)

[Term]
id: ECTO:9000179
name: exposure to manganese cation
def: "An exposure to manganese cation." []
synonym: "manganese cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9001154 ! exposure to elemental manganese
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25155 ! has exposure stimulus manganese cation
relationship: RO:0002309 CHEBI:25155 ! has exposure stimulus manganese cation

[Term]
id: ECTO:9000180
name: exposure to zinc cation
def: "An exposure to zinc cation." []
synonym: "zinc cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9001306 ! exposure to elemental zinc
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63056 ! has exposure stimulus zinc cation
relationship: RO:0002309 CHEBI:63056 ! has exposure stimulus zinc cation

[Term]
id: ECTO:9000181
name: exposure to aluminium cation
def: "An exposure to aluminium cation." []
synonym: "aluminium cation exposure" EXACT []
is_a: ECTO:9000029 ! exposure to aluminum
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63062 ! has exposure stimulus aluminium cation
relationship: RO:0002309 CHEBI:63062 ! has exposure stimulus aluminium cation

[Term]
id: ECTO:9000182
name: exposure to nickel cation
def: "An exposure to nickel cation." []
synonym: "nickel cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25516 ! has exposure stimulus nickel cation
relationship: RO:0002309 CHEBI:25516 ! has exposure stimulus nickel cation

[Term]
id: ECTO:9000183
name: exposure to chlorate
def: "An exposure to chlorate." []
synonym: "chlorate exposure" EXACT []
is_a: ECTO:9002504 ! exposure to chlorine oxoanion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49709 ! has exposure stimulus chlorate
relationship: RO:0002309 CHEBI:49709 ! has exposure stimulus chlorate

[Term]
id: ECTO:9000184
name: exposure to caesium
def: "An exposure to caesium molecular entity." []
synonym: "caesium molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37128 ! has exposure stimulus caesium molecular entity
relationship: RO:0002309 CHEBI:37128 ! has exposure stimulus caesium molecular entity

[Term]
id: ECTO:9000185
name: exposure to nitrate
def: "An exposure to nitrate." []
synonym: "nitrate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17632 ! has exposure stimulus nitrate
relationship: RO:0002309 CHEBI:17632 ! has exposure stimulus nitrate

[Term]
id: ECTO:9000187
name: exposure to chitin
def: "An exposure to chitin." []
synonym: "chitin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17029 ! has exposure stimulus chitin
relationship: RO:0002309 CHEBI:17029 ! has exposure stimulus chitin

[Term]
id: ECTO:9000188
name: exposure to lithium(1+)
def: "An exposure to lithium(1+)." []
synonym: "lithium(1+) exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49713 ! has exposure stimulus lithium(1+)
relationship: RO:0002309 CHEBI:49713 ! has exposure stimulus lithium(1+)

[Term]
id: ECTO:9000189
name: exposure to proline
def: "An exposure to proline." []
synonym: "proline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26271 ! has exposure stimulus proline
relationship: RO:0002309 CHEBI:26271 ! has exposure stimulus proline

[Term]
id: ECTO:9000190
name: exposure to organonitrogen compound
def: "An exposure to organonitrogen compound." []
synonym: "organonitrogen compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35352 ! has exposure stimulus organonitrogen compound
relationship: RO:0002309 CHEBI:35352 ! has exposure stimulus organonitrogen compound

[Term]
id: ECTO:9000191
name: exposure to thiamine(1+)
def: "An exposure to thiamine(1+)." []
synonym: "thiamine(1+) exposure" EXACT []
is_a: ECTO:9000147 ! exposure to thiamine
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18385 ! has exposure stimulus thiamine(1+)
relationship: RO:0002309 CHEBI:18385 ! has exposure stimulus thiamine(1+)

[Term]
id: ECTO:9000192
name: exposure to selenium ion
def: "An exposure to selenium ion." []
synonym: "selenium ion exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000950 ! exposure to selenium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60250 ! has exposure stimulus selenium ion
relationship: RO:0002309 CHEBI:60250 ! has exposure stimulus selenium ion

[Term]
id: ECTO:9000193
name: exposure to silver cation
def: "An exposure to silver cation." []
synonym: "silver cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9001252 ! exposure to elemental silver
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60253 ! has exposure stimulus silver cation
relationship: RO:0002309 CHEBI:60253 ! has exposure stimulus silver cation

[Term]
id: ECTO:9000194
name: exposure to lead cation
def: "An exposure to lead cation." []
synonym: "lead cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9000945 ! exposure to lead
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60252 ! has exposure stimulus lead cation
relationship: RO:0002309 CHEBI:60252 ! has exposure stimulus lead cation

[Term]
id: ECTO:9000195
name: exposure to trehalose
def: "An exposure to trehalose." []
synonym: "trehalose exposure" EXACT []
is_a: ECTO:9000240 ! exposure to disaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27082 ! has exposure stimulus trehalose
relationship: RO:0002309 CHEBI:27082 ! has exposure stimulus trehalose

[Term]
id: ECTO:9000196
name: exposure to sulfur dioxide
def: "An exposure to sulfur dioxide." []
synonym: "sulfur dioxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18422 ! has exposure stimulus sulfur dioxide
relationship: RO:0002309 CHEBI:18422 ! has exposure stimulus sulfur dioxide

[Term]
id: ECTO:9000197
name: exposure to mannitol
def: "An exposure to mannitol." []
synonym: "mannitol exposure" EXACT []
is_a: ECTO:9001449 ! exposure to alditol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29864 ! has exposure stimulus mannitol
relationship: RO:0002309 CHEBI:29864 ! has exposure stimulus mannitol

[Term]
id: ECTO:9000199
name: exposure to cycloalkane
def: "An exposure to cycloalkane." []
synonym: "cycloalkane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23453 ! has exposure stimulus cycloalkane
relationship: RO:0002309 CHEBI:23453 ! has exposure stimulus cycloalkane

[Term]
id: ECTO:9000200
name: exposure to isoquinoline alkaloid
def: "An exposure to isoquinoline alkaloid." []
synonym: "isoquinoline alkaloid exposure" EXACT []
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24921 ! has exposure stimulus isoquinoline alkaloid
relationship: RO:0002309 CHEBI:24921 ! has exposure stimulus isoquinoline alkaloid

[Term]
id: ECTO:9000201
name: exposure to tropane
def: "An exposure to tropane." []
synonym: "tropane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35615 ! has exposure stimulus tropane
relationship: RO:0002309 CHEBI:35615 ! has exposure stimulus tropane

[Term]
id: ECTO:9000202
name: exposure to purines
def: "An exposure to purines." []
synonym: "purines exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26401 ! has exposure stimulus purines
relationship: RO:0002309 CHEBI:26401 ! has exposure stimulus purines

[Term]
id: ECTO:9000203
name: exposure to amine
def: "An exposure to amine." []
synonym: "amine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32952 ! has exposure stimulus amine
relationship: RO:0002309 CHEBI:32952 ! has exposure stimulus amine

[Term]
id: ECTO:9000204
name: exposure to fluoxetine
def: "An exposure to fluoxetine." []
synonym: "fluoxetine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5118 ! has exposure stimulus fluoxetine
relationship: RO:0002309 CHEBI:5118 ! has exposure stimulus fluoxetine

[Term]
id: ECTO:9000205
name: exposure to caffeine
def: "An exposure to caffeine." []
synonym: "caffeine exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27732 ! has exposure stimulus caffeine
relationship: RO:0002309 CHEBI:27732 ! has exposure stimulus caffeine

[Term]
id: ECTO:9000206
name: exposure to brefeldin A
def: "An exposure to brefeldin A." []
synonym: "brefeldin A exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48080 ! has exposure stimulus brefeldin A
relationship: RO:0002309 CHEBI:48080 ! has exposure stimulus brefeldin A

[Term]
id: ECTO:9000209
name: exposure to cobalt cation
def: "An exposure to cobalt cation." []
synonym: "cobalt cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23336 ! has exposure stimulus cobalt cation
relationship: RO:0002309 CHEBI:23336 ! has exposure stimulus cobalt cation

[Term]
id: ECTO:9000210
name: exposure to magnesium cation
def: "An exposure to magnesium cation." []
synonym: "magnesium cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39127 ! has exposure stimulus magnesium cation
relationship: RO:0002309 CHEBI:39127 ! has exposure stimulus magnesium cation

[Term]
id: ECTO:9000211
name: exposure to rhamnose
def: "An exposure to rhamnose." []
synonym: "rhamnose exposure" EXACT []
is_a: ECTO:9000164 ! exposure to hexose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26546 ! has exposure stimulus rhamnose
relationship: RO:0002309 CHEBI:26546 ! has exposure stimulus rhamnose

[Term]
id: ECTO:9000212
name: exposure to estradiol
def: "An exposure to estradiol." []
synonym: "estradiol exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23965 ! has exposure stimulus estradiol
relationship: RO:0002309 CHEBI:23965 ! has exposure stimulus estradiol

[Term]
id: ECTO:9000213
name: exposure to peptidoglycan
def: "An exposure to peptidoglycan." []
synonym: "peptidoglycan exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8005 ! has exposure stimulus peptidoglycan
relationship: RO:0002309 CHEBI:8005 ! has exposure stimulus peptidoglycan

[Term]
id: ECTO:9000214
name: exposure to muramyl dipeptide
def: "An exposure to muramyl dipeptide." []
synonym: "muramyl dipeptide exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59414 ! has exposure stimulus muramyl dipeptide
relationship: RO:0002309 CHEBI:59414 ! has exposure stimulus muramyl dipeptide

[Term]
id: ECTO:9000215
name: exposure to lipopolysaccharide
def: "An exposure to lipopolysaccharide." []
synonym: "lipopolysaccharide exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16412 ! has exposure stimulus lipopolysaccharide
relationship: RO:0002309 CHEBI:16412 ! has exposure stimulus lipopolysaccharide

[Term]
id: ECTO:9000216
name: exposure to retinoic acid
def: "An exposure to retinoic acid." []
synonym: "retinoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001346 ! exposure to retinoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26536 ! has exposure stimulus retinoic acid
relationship: RO:0002309 CHEBI:26536 ! has exposure stimulus retinoic acid

[Term]
id: ECTO:9000217
name: exposure to progesterone
def: "An exposure to progesterone." []
synonym: "progesterone exposure" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
is_a: ECTO:0000258 ! exposure to steroid hormone
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17026 ! has exposure stimulus progesterone
relationship: RO:0002309 CHEBI:17026 ! has exposure stimulus progesterone

[Term]
id: ECTO:9000218
name: obsolete vitamin K exposure
is_obsolete: true
replaced_by: ECTO:9000139

[Term]
id: ECTO:9000219
name: obsolete menaquinone exposure
is_obsolete: true
replaced_by: ECTO:9000141

[Term]
id: ECTO:9000220
name: obsolete phylloquinone exposure
is_obsolete: true
replaced_by: ECTO:9000140

[Term]
id: ECTO:9000222
name: exposure to hydroperoxide
def: "An exposure to hydroperoxide." []
synonym: "hydroperoxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35923 ! has exposure stimulus hydroperoxide
relationship: RO:0002309 CHEBI:35923 ! has exposure stimulus hydroperoxide

[Term]
id: ECTO:9000223
name: exposure to alkyl hydroperoxide
def: "An exposure to alkyl hydroperoxide." []
synonym: "alkyl hydroperoxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000222 ! exposure to hydroperoxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61050 ! has exposure stimulus alkyl hydroperoxide
relationship: RO:0002309 CHEBI:61050 ! has exposure stimulus alkyl hydroperoxide

[Term]
id: ECTO:9000224
name: exposure to vitamin E
def: "An exposure to vitamin E." []
synonym: "vitamin E exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33234 ! has exposure stimulus vitamin E
relationship: RO:0002309 CHEBI:33234 ! has exposure stimulus vitamin E

[Term]
id: ECTO:9000225
name: exposure to ATP
def: "An exposure to ATP." []
synonym: "ATP exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9002338 ! exposure to nucleotide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15422 ! has exposure stimulus ATP
relationship: RO:0002309 CHEBI:15422 ! has exposure stimulus ATP

[Term]
id: ECTO:9000226
name: obsolete riboflavin exposure
is_obsolete: true
replaced_by: ECTO:9000149

[Term]
id: ECTO:9000228
name: exposure to testosterone
def: "An exposure to testosterone." []
synonym: "testosterone exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17347 ! has exposure stimulus testosterone
relationship: RO:0002309 CHEBI:17347 ! has exposure stimulus testosterone

[Term]
id: ECTO:9000229
name: exposure to cobalamin
def: "An exposure to cobalamin." []
synonym: "cobalamin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000943 ! exposure to cobalt
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30411 ! has exposure stimulus cobalamin
relationship: RO:0002309 CHEBI:30411 ! has exposure stimulus cobalamin

[Term]
id: ECTO:9000231
name: exposure to hydroxyisoflavone
def: "An exposure to hydroxyisoflavone." []
synonym: "hydroxyisoflavone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38755 ! has exposure stimulus hydroxyisoflavone
relationship: RO:0002309 CHEBI:38755 ! has exposure stimulus hydroxyisoflavone

[Term]
id: ECTO:9000232
name: exposure to genistein
def: "An exposure to genistein." []
synonym: "genistein exposure" EXACT []
is_a: ECTO:9000231 ! exposure to hydroxyisoflavone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28088 ! has exposure stimulus genistein
relationship: RO:0002309 CHEBI:28088 ! has exposure stimulus genistein

[Term]
id: ECTO:9000233
name: exposure to glucagon
def: "An exposure to glucagon." []
synonym: "glucagon exposure" EXACT []
is_a: ECTO:9000273 ! exposure to peptide hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5391 ! has exposure stimulus glucagon
relationship: RO:0002309 CHEBI:5391 ! has exposure stimulus glucagon

[Term]
id: ECTO:9000236
name: exposure to triglyceride
def: "An exposure to triglyceride." []
synonym: "triglyceride exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17855 ! has exposure stimulus triglyceride
relationship: RO:0002309 CHEBI:17855 ! has exposure stimulus triglyceride

[Term]
id: ECTO:9000237
name: obsolete silicon dioxide exposure
is_obsolete: true
replaced_by: ECTO:9000073

[Term]
id: ECTO:9000238
name: exposure to oleate
def: "An exposure to oleate." []
synonym: "oleate exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30823 ! has exposure stimulus oleate
relationship: RO:0002309 CHEBI:30823 ! has exposure stimulus oleate

[Term]
id: ECTO:9000239
name: exposure to monosaccharide
def: "An exposure to monosaccharide." []
synonym: "monosaccharide exposure" EXACT []
is_a: ECTO:9000162 ! exposure to carbohydrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35381 ! has exposure stimulus monosaccharide
relationship: RO:0002309 CHEBI:35381 ! has exposure stimulus monosaccharide

[Term]
id: ECTO:9000240
name: exposure to disaccharide
def: "An exposure to disaccharide." []
synonym: "disaccharide exposure" EXACT []
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36233 ! has exposure stimulus disaccharide
relationship: RO:0002309 CHEBI:36233 ! has exposure stimulus disaccharide

[Term]
id: ECTO:9000241
name: exposure to maltose
def: "An exposure to maltose." []
synonym: "maltose exposure" EXACT []
is_a: ECTO:9000240 ! exposure to disaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17306 ! has exposure stimulus maltose
relationship: RO:0002309 CHEBI:17306 ! has exposure stimulus maltose

[Term]
id: ECTO:9000243
name: exposure to vitamin B6
def: "An exposure to vitamin B6." []
synonym: "vitamin B6 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27306 ! has exposure stimulus vitamin B6
relationship: RO:0002309 CHEBI:27306 ! has exposure stimulus vitamin B6

[Term]
id: ECTO:9000244
name: exposure to prostaglandin
def: "An exposure to prostaglandin." []
synonym: "prostaglandin exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26333 ! has exposure stimulus prostaglandin
relationship: RO:0002309 CHEBI:26333 ! has exposure stimulus prostaglandin

[Term]
id: ECTO:9000245
name: exposure to prostaglandins E
def: "An exposure to prostaglandins E." []
synonym: "prostaglandins E exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000244 ! exposure to prostaglandin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26338 ! has exposure stimulus prostaglandins E
relationship: RO:0002309 CHEBI:26338 ! has exposure stimulus prostaglandins E

[Term]
id: ECTO:9000246
name: exposure to prostaglandins F
def: "An exposure to prostaglandins F." []
synonym: "prostaglandins F exposure" EXACT []
is_a: ECTO:9000244 ! exposure to prostaglandin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26340 ! has exposure stimulus prostaglandins F
relationship: RO:0002309 CHEBI:26340 ! has exposure stimulus prostaglandins F

[Term]
id: ECTO:9000247
name: exposure to prostaglandins I
def: "An exposure to prostaglandins I." []
synonym: "prostaglandins I exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000244 ! exposure to prostaglandin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26345 ! has exposure stimulus prostaglandins I
relationship: RO:0002309 CHEBI:26345 ! has exposure stimulus prostaglandins I

[Term]
id: ECTO:9000248
name: exposure to histamine
def: "An exposure to histamine." []
synonym: "histamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18295 ! has exposure stimulus histamine
relationship: RO:0002309 CHEBI:18295 ! has exposure stimulus histamine

[Term]
id: ECTO:9000249
name: exposure to ecdysone
def: "An exposure to ecdysone." []
synonym: "ecdysone exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000264 ! exposure to sterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16688 ! has exposure stimulus ecdysone
relationship: RO:0002309 CHEBI:16688 ! has exposure stimulus ecdysone

[Term]
id: ECTO:9000250
name: exposure to nicotine
def: "An exposure to nicotine." []
synonym: "nicotine exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18723 ! has exposure stimulus nicotine
relationship: RO:0002309 CHEBI:18723 ! has exposure stimulus nicotine

[Term]
id: ECTO:9000251
name: exposure to stilbenoid
def: "An exposure to stilbenoid." []
synonym: "stilbenoid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26776 ! has exposure stimulus stilbenoid
relationship: RO:0002309 CHEBI:26776 ! has exposure stimulus stilbenoid

[Term]
id: ECTO:9000252
name: exposure to nitrogen dioxide
def: "An exposure to nitrogen dioxide." []
synonym: "nitrogen dioxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33101 ! has exposure stimulus nitrogen dioxide
relationship: RO:0002309 CHEBI:33101 ! has exposure stimulus nitrogen dioxide

[Term]
id: ECTO:9000253
name: exposure to potassium(1+)
def: "An exposure to potassium(1+)." []
synonym: "potassium(1+) exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29103 ! has exposure stimulus potassium(1+)
relationship: RO:0002309 CHEBI:29103 ! has exposure stimulus potassium(1+)

[Term]
id: ECTO:9000254
name: exposure to trichostatin A
def: "An exposure to trichostatin A." []
synonym: "trichostatin A exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46024 ! has exposure stimulus trichostatin A
relationship: RO:0002309 CHEBI:46024 ! has exposure stimulus trichostatin A

[Term]
id: ECTO:9000255
name: exposure to amiloride
def: "An exposure to amiloride." []
synonym: "amiloride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2639 ! has exposure stimulus amiloride
relationship: RO:0002309 CHEBI:2639 ! has exposure stimulus amiloride

[Term]
id: ECTO:9000256
name: exposure to methylamine
def: "An exposure to methylamine." []
synonym: "methylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16830 ! has exposure stimulus methylamine
relationship: RO:0002309 CHEBI:16830 ! has exposure stimulus methylamine

[Term]
id: ECTO:9000257
name: exposure to methylphenidate
def: "An exposure to methylphenidate." []
synonym: "methylphenidate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6887 ! has exposure stimulus methylphenidate
relationship: RO:0002309 CHEBI:6887 ! has exposure stimulus methylphenidate

[Term]
id: ECTO:9000258
name: exposure to gemcitabine
def: "An exposure to gemcitabine." []
synonym: "gemcitabine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:175901 ! has exposure stimulus gemcitabine
relationship: RO:0002309 CHEBI:175901 ! has exposure stimulus gemcitabine

[Term]
id: ECTO:9000259
name: exposure to statin
def: "An exposure to statin." []
synonym: "statin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87631 ! has exposure stimulus statin
relationship: RO:0002309 CHEBI:87631 ! has exposure stimulus statin

[Term]
id: ECTO:9000260
name: exposure to lapatinib
def: "An exposure to lapatinib." []
synonym: "lapatinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49603 ! has exposure stimulus lapatinib
relationship: RO:0002309 CHEBI:49603 ! has exposure stimulus lapatinib

[Term]
id: ECTO:9000261
name: exposure to 5-fluorouracil
def: "An exposure to 5-fluorouracil." []
synonym: "5-fluorouracil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46345 ! has exposure stimulus 5-fluorouracil
relationship: RO:0002309 CHEBI:46345 ! has exposure stimulus 5-fluorouracil

[Term]
id: ECTO:9000262
name: exposure to iloperidone
def: "An exposure to iloperidone." []
synonym: "iloperidone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000318 ! exposure to monoamine
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65173 ! has exposure stimulus iloperidone
relationship: RO:0002309 CHEBI:65173 ! has exposure stimulus iloperidone

[Term]
id: ECTO:9000263
name: exposure to ximelagatran
def: "An exposure to ximelagatran." []
synonym: "ximelagatran exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65172 ! has exposure stimulus ximelagatran
relationship: RO:0002309 CHEBI:65172 ! has exposure stimulus ximelagatran

[Term]
id: ECTO:9000264
name: exposure to sterol
def: "An exposure to sterol." []
synonym: "sterol exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15889 ! has exposure stimulus sterol
relationship: RO:0002309 CHEBI:15889 ! has exposure stimulus sterol

[Term]
id: ECTO:9000265
name: exposure to cocaine
def: "An exposure to cocaine." []
synonym: "cocaine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27958 ! has exposure stimulus cocaine
relationship: RO:0002309 CHEBI:27958 ! has exposure stimulus cocaine

[Term]
id: ECTO:9000266
name: obsolete chemical entity exposure
is_obsolete: true
replaced_by: ECTO:0000231

[Term]
id: ECTO:9000267
name: exposure to hydrogen peroxide
def: "An exposure to hydrogen peroxide." []
synonym: "hydrogen peroxide exposure" EXACT []
is_a: ECTO:9000150 ! exposure to reactive oxygen species
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16240 ! has exposure stimulus hydrogen peroxide
relationship: RO:0002309 CHEBI:16240 ! has exposure stimulus hydrogen peroxide

[Term]
id: ECTO:9000268
name: exposure to amino acid
def: "An exposure to amino acid." []
synonym: "amino acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33709 ! has exposure stimulus amino acid
relationship: RO:0002309 CHEBI:33709 ! has exposure stimulus amino acid

[Term]
id: ECTO:9000269
name: exposure to leucine
def: "An exposure to leucine." []
synonym: "leucine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25017 ! has exposure stimulus leucine
relationship: RO:0002309 CHEBI:25017 ! has exposure stimulus leucine

[Term]
id: ECTO:9000270
name: exposure to morphine
def: "An exposure to morphine." []
synonym: "morphine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000200 ! exposure to isoquinoline alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17303 ! has exposure stimulus morphine
relationship: RO:0002309 CHEBI:17303 ! has exposure stimulus morphine

[Term]
id: ECTO:9000271
name: exposure to alkaloid
def: "An exposure to alkaloid." []
synonym: "alkaloid exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22315 ! has exposure stimulus alkaloid
relationship: RO:0002309 CHEBI:22315 ! has exposure stimulus alkaloid

[Term]
id: ECTO:9000272
name: exposure to double-stranded RNA
def: "An exposure to double-stranded RNA." []
synonym: "double-stranded RNA exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67208 ! has exposure stimulus double-stranded RNA
relationship: RO:0002309 CHEBI:67208 ! has exposure stimulus double-stranded RNA

[Term]
id: ECTO:9000273
name: exposure to peptide hormone
def: "An exposure to peptide hormone." []
synonym: "peptide hormone exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25905 ! has exposure stimulus peptide hormone
relationship: RO:0002309 CHEBI:25905 ! has exposure stimulus peptide hormone

[Term]
id: ECTO:9000274
name: exposure to corticotropin-releasing hormone
def: "An exposure to corticotropin-releasing hormone." []
synonym: "corticotropin-releasing hormone exposure" EXACT []
is_a: ECTO:9000273 ! exposure to peptide hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65311 ! has exposure stimulus corticotropin-releasing hormone
relationship: RO:0002309 CHEBI:65311 ! has exposure stimulus corticotropin-releasing hormone

[Term]
id: ECTO:9000275
name: exposure to amylopectin
def: "An exposure to amylopectin." []
synonym: "amylopectin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28057 ! has exposure stimulus amylopectin
relationship: RO:0002309 CHEBI:28057 ! has exposure stimulus amylopectin

[Term]
id: ECTO:9000276
name: exposure to pullulan
def: "An exposure to pullulan." []
synonym: "pullulan exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27941 ! has exposure stimulus pullulan
relationship: RO:0002309 CHEBI:27941 ! has exposure stimulus pullulan

[Term]
id: ECTO:9000278
name: exposure to ether
def: "An exposure to ether." []
synonym: "ether exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25698 ! has exposure stimulus ether
relationship: RO:0002309 CHEBI:25698 ! has exposure stimulus ether

[Term]
id: ECTO:9000279
name: exposure to bacteriocin
def: "An exposure to bacteriocin." []
synonym: "bacteriocin exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48081 ! has exposure stimulus bacteriocin
relationship: RO:0002309 CHEBI:48081 ! has exposure stimulus bacteriocin

[Term]
id: ECTO:9000280
name: exposure to streptomycin
def: "An exposure to streptomycin." []
synonym: "streptomycin exposure" EXACT []
is_a: ECTO:9002231 ! exposure to aminoglycoside antibiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17076 ! has exposure stimulus streptomycin
relationship: RO:0002309 CHEBI:17076 ! has exposure stimulus streptomycin

[Term]
id: ECTO:9000281
name: exposure to DDT
def: "An exposure to DDT." []
synonym: "DDT exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16130 ! has exposure stimulus DDT
relationship: RO:0002309 CHEBI:16130 ! has exposure stimulus DDT

[Term]
id: ECTO:9000282
name: exposure to carbamate
def: "An exposure to carbamate." []
synonym: "carbamate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:13941 ! has exposure stimulus carbamate
relationship: RO:0002309 CHEBI:13941 ! has exposure stimulus carbamate

[Term]
id: ECTO:9000283
name: exposure to cyclodiene organochlorine insecticide
def: "An exposure to cyclodiene organochlorine insecticide." []
synonym: "cyclodiene organochlorine insecticide exposure" EXACT []
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23457 ! has exposure stimulus cyclodiene organochlorine insecticide
relationship: RO:0002309 CHEBI:23457 ! has exposure stimulus cyclodiene organochlorine insecticide

[Term]
id: ECTO:9000284
name: exposure to organophosphorus compound
def: "An exposure to organophosphorus compound." []
synonym: "organophosphorus compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25710 ! has exposure stimulus organophosphorus compound
relationship: RO:0002309 CHEBI:25710 ! has exposure stimulus organophosphorus compound

[Term]
id: ECTO:9000285
name: obsolete arsenic molecular entity exposure
is_obsolete: true
replaced_by: ECTO:9000032

[Term]
id: ECTO:9000286
name: exposure to cadmium cation
def: "An exposure to cadmium cation." []
synonym: "cadmium cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63063 ! has exposure stimulus cadmium cation
relationship: RO:0002309 CHEBI:63063 ! has exposure stimulus cadmium cation

[Term]
id: ECTO:9000288
name: exposure to copper cation
def: "An exposure to copper cation." []
synonym: "copper cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9000944 ! exposure to copper
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23378 ! has exposure stimulus copper cation
relationship: RO:0002309 CHEBI:23378 ! has exposure stimulus copper cation

[Term]
id: ECTO:9000289
name: exposure to mercury cation
def: "An exposure to mercury cation." []
synonym: "mercury cation exposure" EXACT []
is_a: ECTO:0001571 ! exposure to mercury
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25197 ! has exposure stimulus mercury cation
relationship: RO:0002309 CHEBI:25197 ! has exposure stimulus mercury cation

[Term]
id: ECTO:9000290
name: exposure to tellurium ion
def: "An exposure to tellurium ion." []
synonym: "tellurium ion exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60271 ! has exposure stimulus tellurium ion
relationship: RO:0002309 CHEBI:60271 ! has exposure stimulus tellurium ion

[Term]
id: ECTO:9000291
name: exposure to cycloheximide
def: "An exposure to cycloheximide." []
synonym: "cycloheximide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27641 ! has exposure stimulus cycloheximide
relationship: RO:0002309 CHEBI:27641 ! has exposure stimulus cycloheximide

[Term]
id: ECTO:9000294
name: exposure to mineralocorticoid
def: "An exposure to mineralocorticoid." []
synonym: "mineralocorticoid exposure" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
is_a: ECTO:0000258 ! exposure to steroid hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25354 ! has exposure stimulus mineralocorticoid
relationship: RO:0002309 CHEBI:25354 ! has exposure stimulus mineralocorticoid

[Term]
id: ECTO:9000296
name: exposure to cortisone
def: "An exposure to cortisone." []
synonym: "cortisone exposure" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16962 ! has exposure stimulus cortisone
relationship: RO:0002309 CHEBI:16962 ! has exposure stimulus cortisone

[Term]
id: ECTO:9000297
name: exposure to cortisol
def: "An exposure to cortisol." []
synonym: "cortisol exposure" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17650 ! has exposure stimulus cortisol
relationship: RO:0002309 CHEBI:17650 ! has exposure stimulus cortisol

[Term]
id: ECTO:9000298
name: exposure to 3',5'-cyclic AMP
def: "An exposure to 3',5'-cyclic AMP." []
synonym: "3',5'-cyclic AMP exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9002338 ! exposure to nucleotide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17489 ! has exposure stimulus 3',5'-cyclic AMP
relationship: RO:0002309 CHEBI:17489 ! has exposure stimulus 3',5'-cyclic AMP

[Term]
id: ECTO:9000299
name: exposure to calcium cation
def: "An exposure to calcium cation." []
synonym: "calcium cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39123 ! has exposure stimulus calcium cation
relationship: RO:0002309 CHEBI:39123 ! has exposure stimulus calcium cation

[Term]
id: ECTO:9000301
name: exposure to methylglyoxal
def: "An exposure to methylglyoxal." []
synonym: "methylglyoxal exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17158 ! has exposure stimulus methylglyoxal
relationship: RO:0002309 CHEBI:17158 ! has exposure stimulus methylglyoxal

[Term]
id: ECTO:9000302
name: exposure to methylmercury(1+)
def: "An exposure to methylmercury(1+)." []
synonym: "methylmercury(1+) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0001571 ! exposure to mercury
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49747 ! has exposure stimulus methylmercury(1+)
relationship: RO:0002309 CHEBI:49747 ! has exposure stimulus methylmercury(1+)

[Term]
id: ECTO:9000303
name: exposure to lipoprotein
def: "An exposure to lipoprotein." []
synonym: "lipoprotein exposure" EXACT []
is_a: ECTO:9002133 ! exposure to protein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6495 ! has exposure stimulus lipoprotein
relationship: RO:0002309 CHEBI:6495 ! has exposure stimulus lipoprotein

[Term]
id: ECTO:9000304
name: exposure to ammonium ion
def: "An exposure to ammonium ion derivative." []
synonym: "ammonium ion derivative exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35274 ! has exposure stimulus ammonium ion derivative
relationship: RO:0002309 CHEBI:35274 ! has exposure stimulus ammonium ion derivative

[Term]
id: ECTO:9000305
name: exposure to 3',5'-cyclic GMP
def: "An exposure to 3',5'-cyclic GMP." []
synonym: "3',5'-cyclic GMP exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9002338 ! exposure to nucleotide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16356 ! has exposure stimulus 3',5'-cyclic GMP
relationship: RO:0002309 CHEBI:16356 ! has exposure stimulus 3',5'-cyclic GMP

[Term]
id: ECTO:9000306
name: exposure to lipoteichoic acid
def: "An exposure to lipoteichoic acid." []
synonym: "lipoteichoic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28640 ! has exposure stimulus lipoteichoic acid
relationship: RO:0002309 CHEBI:28640 ! has exposure stimulus lipoteichoic acid

[Term]
id: ECTO:9000307
name: exposure to platinum cation
def: "An exposure to platinum cation." []
synonym: "platinum cation exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9000949 ! exposure to platinum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63526 ! has exposure stimulus platinum cation
relationship: RO:0002309 CHEBI:63526 ! has exposure stimulus platinum cation

[Term]
id: ECTO:9000308
name: exposure to fatty acid
def: "An exposure to fatty acid." []
synonym: "fatty acid exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35366 ! has exposure stimulus fatty acid
relationship: RO:0002309 CHEBI:35366 ! has exposure stimulus fatty acid

[Term]
id: ECTO:9000309
name: exposure to linoleate
def: "An exposure to linoleate." []
synonym: "linoleate exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30245 ! has exposure stimulus linoleate
relationship: RO:0002309 CHEBI:30245 ! has exposure stimulus linoleate

[Term]
id: ECTO:9000310
name: exposure to cholesterol
def: "An exposure to cholesterol." []
synonym: "cholesterol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000264 ! exposure to sterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16113 ! has exposure stimulus cholesterol
relationship: RO:0002309 CHEBI:16113 ! has exposure stimulus cholesterol

[Term]
id: ECTO:9000311
name: exposure to biotin
def: "An exposure to biotin." []
synonym: "biotin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15956 ! has exposure stimulus biotin
relationship: RO:0002309 CHEBI:15956 ! has exposure stimulus biotin

[Term]
id: ECTO:9000313
name: exposure to mycophenolate
def: "An exposure to mycophenolate." []
synonym: "mycophenolate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62932 ! has exposure stimulus mycophenolate
relationship: RO:0002309 CHEBI:62932 ! has exposure stimulus mycophenolate

[Term]
id: ECTO:9000314
name: exposure to dexamethasone
def: "An exposure to dexamethasone." []
synonym: "dexamethasone exposure" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41879 ! has exposure stimulus dexamethasone
relationship: RO:0002309 CHEBI:41879 ! has exposure stimulus dexamethasone

[Term]
id: ECTO:9000315
name: exposure to indole-3-methanol
def: "An exposure to indole-3-methanol." []
synonym: "indole-3-methanol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24814 ! has exposure stimulus indole-3-methanol
relationship: RO:0002309 CHEBI:24814 ! has exposure stimulus indole-3-methanol

[Term]
id: ECTO:9000316
name: exposure to nitric oxide
def: "An exposure to nitric oxide." []
synonym: "nitric oxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16480 ! has exposure stimulus nitric oxide
relationship: RO:0002309 CHEBI:16480 ! has exposure stimulus nitric oxide

[Term]
id: ECTO:9000317
name: exposure to prostaglandins D
def: "An exposure to prostaglandins D." []
synonym: "prostaglandins D exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000244 ! exposure to prostaglandin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26337 ! has exposure stimulus prostaglandins D
relationship: RO:0002309 CHEBI:26337 ! has exposure stimulus prostaglandins D

[Term]
id: ECTO:9000318
name: exposure to monoamine
def: "An exposure to monoamine." []
synonym: "monoamine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63534 ! has exposure stimulus monoamine
relationship: RO:0002309 CHEBI:63534 ! has exposure stimulus monoamine

[Term]
id: ECTO:9000319
name: exposure to catecholamine
def: "An exposure to catecholamine." []
synonym: "catecholamine exposure" EXACT []
is_a: ECTO:9000318 ! exposure to monoamine
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33567 ! has exposure stimulus catecholamine
relationship: RO:0002309 CHEBI:33567 ! has exposure stimulus catecholamine

[Term]
id: ECTO:9000320
name: exposure to adrenaline
def: "An exposure to adrenaline." []
synonym: "adrenaline exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33568 ! has exposure stimulus adrenaline
relationship: RO:0002309 CHEBI:33568 ! has exposure stimulus adrenaline

[Term]
id: ECTO:9000321
name: exposure to noradrenaline
def: "An exposure to noradrenaline." []
synonym: "noradrenaline exposure" EXACT []
is_a: ECTO:9000319 ! exposure to catecholamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33569 ! has exposure stimulus noradrenaline
relationship: RO:0002309 CHEBI:33569 ! has exposure stimulus noradrenaline

[Term]
id: ECTO:9000322
name: exposure to bismuth ion
def: "An exposure to bismuth ion." []
synonym: "bismuth ion exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85543 ! has exposure stimulus bismuth ion
relationship: RO:0002309 CHEBI:85543 ! has exposure stimulus bismuth ion

[Term]
id: ECTO:9000323
name: exposure to methyl methanesulfonate
def: "An exposure to methyl methanesulfonate." []
synonym: "methyl methanesulfonate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25255 ! has exposure stimulus methyl methanesulfonate
relationship: RO:0002309 CHEBI:25255 ! has exposure stimulus methyl methanesulfonate

[Term]
id: ECTO:9000324
name: exposure to mercaptoethanol
def: "An exposure to mercaptoethanol." []
synonym: "mercaptoethanol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41218 ! has exposure stimulus mercaptoethanol
relationship: RO:0002309 CHEBI:41218 ! has exposure stimulus mercaptoethanol

[Term]
id: ECTO:9000325
name: exposure to sodium dodecyl sulfate
def: "An exposure to sodium dodecyl sulfate." []
synonym: "sodium dodecyl sulfate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8984 ! has exposure stimulus sodium dodecyl sulfate
relationship: RO:0002309 CHEBI:8984 ! has exposure stimulus sodium dodecyl sulfate

[Term]
id: ECTO:9000326
name: exposure to glucitol
def: "An exposure to glucitol." []
synonym: "glucitol exposure" EXACT []
is_a: ECTO:9001449 ! exposure to alditol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30911 ! has exposure stimulus glucitol
relationship: RO:0002309 CHEBI:30911 ! has exposure stimulus glucitol

[Term]
id: ECTO:9000327
name: exposure to hydroxyurea
def: "An exposure to hydroxyurea." []
synonym: "hydroxyurea exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44423 ! has exposure stimulus hydroxyurea
relationship: RO:0002309 CHEBI:44423 ! has exposure stimulus hydroxyurea

[Term]
id: ECTO:9000328
name: exposure to thiabendazole
def: "An exposure to thiabendazole." []
synonym: "thiabendazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45979 ! has exposure stimulus thiabendazole
relationship: RO:0002309 CHEBI:45979 ! has exposure stimulus thiabendazole

[Term]
id: ECTO:9000329
name: exposure to actinomycin D
def: "An exposure to actinomycin D." []
synonym: "actinomycin D exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27666 ! has exposure stimulus actinomycin D
relationship: RO:0002309 CHEBI:27666 ! has exposure stimulus actinomycin D

[Term]
id: ECTO:9000330
name: exposure to cisplatin
def: "An exposure to cisplatin." []
synonym: "cisplatin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000949 ! exposure to platinum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27899 ! has exposure stimulus cisplatin
relationship: RO:0002309 CHEBI:27899 ! has exposure stimulus cisplatin

[Term]
id: ECTO:9000331
name: exposure to 1,4-dithiothreitol
def: "An exposure to 1,4-dithiothreitol." []
synonym: "1,4-dithiothreitol exposure" EXACT []
is_a: ECTO:9002156 ! exposure to glycol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18320 ! has exposure stimulus 1,4-dithiothreitol
relationship: RO:0002309 CHEBI:18320 ! has exposure stimulus 1,4-dithiothreitol

[Term]
id: ECTO:9000332
name: exposure to amitrole
def: "An exposure to amitrole." []
synonym: "amitrole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:40036 ! has exposure stimulus amitrole
relationship: RO:0002309 CHEBI:40036 ! has exposure stimulus amitrole

[Term]
id: ECTO:9000333
name: exposure to 4-nitroquinoline N-oxide
def: "An exposure to 4-nitroquinoline N-oxide." []
synonym: "4-nitroquinoline N-oxide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16907 ! has exposure stimulus 4-nitroquinoline N-oxide
relationship: RO:0002309 CHEBI:16907 ! has exposure stimulus 4-nitroquinoline N-oxide

[Term]
id: ECTO:9000334
name: exposure to CCCP
def: "An exposure to CCCP." []
synonym: "CCCP exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3259 ! has exposure stimulus CCCP
relationship: RO:0002309 CHEBI:3259 ! has exposure stimulus CCCP

[Term]
id: ECTO:9000335
name: exposure to papulacandin B
def: "An exposure to papulacandin B." []
synonym: "papulacandin B exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:569624 ! has exposure stimulus papulacandin B
relationship: RO:0002309 CHEBI:569624 ! has exposure stimulus papulacandin B

[Term]
id: ECTO:9000336
name: exposure to staurosporine
def: "An exposure to staurosporine." []
synonym: "staurosporine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15738 ! has exposure stimulus staurosporine
relationship: RO:0002309 CHEBI:15738 ! has exposure stimulus staurosporine

[Term]
id: ECTO:9000337
name: exposure to tert-butyl hydroperoxide
def: "An exposure to tert-butyl hydroperoxide." []
synonym: "tert-butyl hydroperoxide exposure" EXACT []
is_a: ECTO:9000223 ! exposure to alkyl hydroperoxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64090 ! has exposure stimulus tert-butyl hydroperoxide
relationship: RO:0002309 CHEBI:64090 ! has exposure stimulus tert-butyl hydroperoxide

[Term]
id: ECTO:9000338
name: exposure to 1,1'-azobis(N,N-dimethylformamide)
def: "An exposure to 1,1'-azobis(N,N-dimethylformamide)." []
synonym: "1,1'-azobis(N,N-dimethylformamide) exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48958 ! has exposure stimulus 1,1'-azobis(N,N-dimethylformamide)
relationship: RO:0002309 CHEBI:48958 ! has exposure stimulus 1,1'-azobis(N,N-dimethylformamide)

[Term]
id: ECTO:9000339
name: exposure to benzoic acid
def: "An exposure to benzoic acid." []
synonym: "benzoic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30746 ! has exposure stimulus benzoic acid
relationship: RO:0002309 CHEBI:30746 ! has exposure stimulus benzoic acid

[Term]
id: ECTO:9000340
name: exposure to indole-3-butyric acid
def: "An exposure to indole-3-butyric acid." []
synonym: "indole-3-butyric acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33070 ! has exposure stimulus indole-3-butyric acid
relationship: RO:0002309 CHEBI:33070 ! has exposure stimulus indole-3-butyric acid

[Term]
id: ECTO:9000341
name: exposure to nitrite
def: "An exposure to nitrite." []
synonym: "nitrite exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16301 ! has exposure stimulus nitrite
relationship: RO:0002309 CHEBI:16301 ! has exposure stimulus nitrite

[Term]
id: ECTO:9000342
name: exposure to histidine
def: "An exposure to histidine." []
synonym: "histidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27570 ! has exposure stimulus histidine
relationship: RO:0002309 CHEBI:27570 ! has exposure stimulus histidine

[Term]
id: ECTO:9000343
name: exposure to phenylalanine
def: "An exposure to phenylalanine." []
synonym: "phenylalanine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28044 ! has exposure stimulus phenylalanine
relationship: RO:0002309 CHEBI:28044 ! has exposure stimulus phenylalanine

[Term]
id: ECTO:9000344
name: exposure to alpha,alpha-trehalose 6-phosphate(2-)
def: "An exposure to alpha,alpha-trehalose 6-phosphate(2-)." []
synonym: "alpha,alpha-trehalose 6-phosphate(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:58429 ! has exposure stimulus alpha,alpha-trehalose 6-phosphate(2-)
relationship: RO:0002309 CHEBI:58429 ! has exposure stimulus alpha,alpha-trehalose 6-phosphate(2-)

[Term]
id: ECTO:9000345
name: exposure to phenylpropanoid
def: "An exposure to phenylpropanoid." []
synonym: "phenylpropanoid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26004 ! has exposure stimulus phenylpropanoid
relationship: RO:0002309 CHEBI:26004 ! has exposure stimulus phenylpropanoid

[Term]
id: ECTO:9000346
name: exposure to L-thyroxine
def: "An exposure to L-thyroxine." []
synonym: "L-thyroxine exposure" EXACT []
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9000470 ! exposure to L-phenylalanine derivative
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18332 ! has exposure stimulus L-thyroxine
relationship: RO:0002309 CHEBI:18332 ! has exposure stimulus L-thyroxine

[Term]
id: ECTO:9000347
name: exposure to azide anion
def: "An exposure to azide anion." []
synonym: "azide anion exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:40910 ! has exposure stimulus azide anion
relationship: RO:0002309 CHEBI:40910 ! has exposure stimulus azide anion

[Term]
id: ECTO:9000349
name: exposure to farnesol
def: "An exposure to farnesol." []
synonym: "farnesol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28600 ! has exposure stimulus farnesol
relationship: RO:0002309 CHEBI:28600 ! has exposure stimulus farnesol

[Term]
id: ECTO:9000350
name: exposure to N-acetyl-D-glucosamine
def: "An exposure to N-acetyl-D-glucosamine." []
synonym: "N-acetyl-D-glucosamine exposure" EXACT []
is_a: ECTO:9002788 ! exposure to N-acetylglucosamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:506227 ! has exposure stimulus N-acetyl-D-glucosamine
relationship: RO:0002309 CHEBI:506227 ! has exposure stimulus N-acetyl-D-glucosamine

[Term]
id: ECTO:9000351
name: exposure to carboplatin
def: "An exposure to carboplatin." []
synonym: "carboplatin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000949 ! exposure to platinum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31355 ! has exposure stimulus carboplatin
relationship: RO:0002309 CHEBI:31355 ! has exposure stimulus carboplatin

[Term]
id: ECTO:9000352
name: exposure to 5-fluoro-2'-deoxyuridine
def: "An exposure to floxuridine." []
synonym: "floxuridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60761 ! has exposure stimulus floxuridine
relationship: RO:0002309 CHEBI:60761 ! has exposure stimulus floxuridine

[Term]
id: ECTO:9000353
name: exposure to cytarabine
def: "An exposure to cytarabine." []
synonym: "cytarabine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000436 ! exposure to glycoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28680 ! has exposure stimulus cytarabine
relationship: RO:0002309 CHEBI:28680 ! has exposure stimulus cytarabine

[Term]
id: ECTO:9000354
name: exposure to olanzapine
def: "An exposure to olanzapine." []
synonym: "olanzapine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7735 ! has exposure stimulus olanzapine
relationship: RO:0002309 CHEBI:7735 ! has exposure stimulus olanzapine

[Term]
id: ECTO:9000355
name: exposure to perphenazine
def: "An exposure to perphenazine." []
synonym: "perphenazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8028 ! has exposure stimulus perphenazine
relationship: RO:0002309 CHEBI:8028 ! has exposure stimulus perphenazine

[Term]
id: ECTO:9000356
name: exposure to quetiapine
def: "An exposure to quetiapine." []
synonym: "quetiapine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8707 ! has exposure stimulus quetiapine
relationship: RO:0002309 CHEBI:8707 ! has exposure stimulus quetiapine

[Term]
id: ECTO:9000357
name: exposure to risperidone
def: "An exposure to risperidone." []
synonym: "risperidone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8871 ! has exposure stimulus risperidone
relationship: RO:0002309 CHEBI:8871 ! has exposure stimulus risperidone

[Term]
id: ECTO:9000358
name: exposure to ziprasidone
def: "An exposure to ziprasidone." []
synonym: "ziprasidone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10119 ! has exposure stimulus ziprasidone
relationship: RO:0002309 CHEBI:10119 ! has exposure stimulus ziprasidone

[Term]
id: ECTO:9000359
name: exposure to clozapine
def: "An exposure to clozapine." []
synonym: "clozapine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3766 ! has exposure stimulus clozapine
relationship: RO:0002309 CHEBI:3766 ! has exposure stimulus clozapine

[Term]
id: ECTO:9000360
name: exposure to chloramphenicol
def: "An exposure to chloramphenicol." []
synonym: "chloramphenicol exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17698 ! has exposure stimulus chloramphenicol
relationship: RO:0002309 CHEBI:17698 ! has exposure stimulus chloramphenicol

[Term]
id: ECTO:9000361
name: exposure to erythromycin
def: "An exposure to erythromycin." []
synonym: "erythromycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48923 ! has exposure stimulus erythromycin
relationship: RO:0002309 CHEBI:48923 ! has exposure stimulus erythromycin

[Term]
id: ECTO:9000362
name: exposure to trichodermin
def: "An exposure to trichodermin." []
synonym: "trichodermin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9688 ! has exposure stimulus trichodermin
relationship: RO:0002309 CHEBI:9688 ! has exposure stimulus trichodermin

[Term]
id: ECTO:9000363
name: exposure to antimycin A
def: "An exposure to antimycin A." []
synonym: "antimycin A exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2762 ! has exposure stimulus antimycin A
relationship: RO:0002309 CHEBI:2762 ! has exposure stimulus antimycin A

[Term]
id: ECTO:9000364
name: exposure to tetracycline
def: "An exposure to tetracycline." []
synonym: "tetracycline exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27902 ! has exposure stimulus tetracycline
relationship: RO:0002309 CHEBI:27902 ! has exposure stimulus tetracycline

[Term]
id: ECTO:9000365
name: exposure to tacrolimus hydrate
def: "An exposure to tacrolimus hydrate." []
synonym: "tacrolimus hydrate exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61057 ! has exposure stimulus tacrolimus hydrate
relationship: RO:0002309 CHEBI:61057 ! has exposure stimulus tacrolimus hydrate

[Term]
id: ECTO:9000366
name: exposure to cytochalasin B
def: "An exposure to cytochalasin B." []
synonym: "cytochalasin B exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23527 ! has exposure stimulus cytochalasin B
relationship: RO:0002309 CHEBI:23527 ! has exposure stimulus cytochalasin B

[Term]
id: ECTO:9000367
name: exposure to leptomycin B
def: "An exposure to leptomycin B." []
synonym: "leptomycin B exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002507 ! exposure to polyunsaturated fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52646 ! has exposure stimulus leptomycin B
relationship: RO:0002309 CHEBI:52646 ! has exposure stimulus leptomycin B

[Term]
id: ECTO:9000368
name: exposure to L-thialysine
def: "An exposure to L-thialysine." []
synonym: "L-thialysine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:497734 ! has exposure stimulus L-thialysine
relationship: RO:0002309 CHEBI:497734 ! has exposure stimulus L-thialysine

[Term]
id: ECTO:9000369
name: exposure to L-canavanine
def: "An exposure to L-canavanine." []
synonym: "L-canavanine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:609827 ! has exposure stimulus L-canavanine
relationship: RO:0002309 CHEBI:609827 ! has exposure stimulus L-canavanine

[Term]
id: ECTO:9000370
name: exposure to sirolimus
def: "An exposure to sirolimus." []
synonym: "sirolimus exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9168 ! has exposure stimulus sirolimus
relationship: RO:0002309 CHEBI:9168 ! has exposure stimulus sirolimus

[Term]
id: ECTO:9000371
name: exposure to L-cysteine
def: "An exposure to L-cysteine." []
synonym: "L-cysteine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17561 ! has exposure stimulus L-cysteine
relationship: RO:0002309 CHEBI:17561 ! has exposure stimulus L-cysteine

[Term]
id: ECTO:9000372
name: exposure to glutathione
def: "An exposure to glutathione." []
synonym: "glutathione exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16856 ! has exposure stimulus glutathione
relationship: RO:0002309 CHEBI:16856 ! has exposure stimulus glutathione

[Term]
id: ECTO:9000376
name: exposure to formic acid
def: "An exposure to formic acid." []
synonym: "formic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30751 ! has exposure stimulus formic acid
relationship: RO:0002309 CHEBI:30751 ! has exposure stimulus formic acid

[Term]
id: ECTO:9000377
name: exposure to furfural
def: "An exposure to furfural." []
synonym: "furfural exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34768 ! has exposure stimulus furfural
relationship: RO:0002309 CHEBI:34768 ! has exposure stimulus furfural

[Term]
id: ECTO:9000378
name: exposure to propan-1-ol
def: "An exposure to propan-1-ol." []
synonym: "propan-1-ol exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28831 ! has exposure stimulus propan-1-ol
relationship: RO:0002309 CHEBI:28831 ! has exposure stimulus propan-1-ol

[Term]
id: ECTO:9000379
name: exposure to decalin
def: "An exposure to decalin." []
synonym: "decalin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38853 ! has exposure stimulus decalin
relationship: RO:0002309 CHEBI:38853 ! has exposure stimulus decalin

[Term]
id: ECTO:9000380
name: exposure to diphenyl ether
def: "An exposure to diphenyl ether." []
synonym: "diphenyl ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39258 ! has exposure stimulus diphenyl ether
relationship: RO:0002309 CHEBI:39258 ! has exposure stimulus diphenyl ether

[Term]
id: ECTO:9000381
name: exposure to tetralin
def: "An exposure to tetralin." []
synonym: "tetralin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35008 ! has exposure stimulus tetralin
relationship: RO:0002309 CHEBI:35008 ! has exposure stimulus tetralin

[Term]
id: ECTO:9000383
name: exposure to p-xylene
def: "An exposure to p-xylene." []
synonym: "p-xylene exposure" EXACT []
is_a: ECTO:9000035 ! exposure to xylene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27417 ! has exposure stimulus p-xylene
relationship: RO:0002309 CHEBI:27417 ! has exposure stimulus p-xylene

[Term]
id: ECTO:9000385
name: exposure to hypochlorite
def: "An exposure to hypochlorite." []
synonym: "hypochlorite exposure" EXACT []
is_a: ECTO:9002504 ! exposure to chlorine oxoanion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29222 ! has exposure stimulus hypochlorite
relationship: RO:0002309 CHEBI:29222 ! has exposure stimulus hypochlorite

[Term]
id: ECTO:9000386
name: exposure to raffinose
def: "An exposure to raffinose." []
synonym: "raffinose exposure" EXACT []
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16634 ! has exposure stimulus raffinose
relationship: RO:0002309 CHEBI:16634 ! has exposure stimulus raffinose

[Term]
id: ECTO:9000387
name: exposure to paracetamol
def: "An exposure to paracetamol." []
synonym: "paracetamol exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46195 ! has exposure stimulus paracetamol
relationship: RO:0002309 CHEBI:46195 ! has exposure stimulus paracetamol

[Term]
id: ECTO:9000388
name: exposure to paclitaxel
def: "An exposure to paclitaxel." []
synonym: "paclitaxel exposure" EXACT []
is_a: ECTO:9002627 ! exposure to taxane diterpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45863 ! has exposure stimulus paclitaxel
relationship: RO:0002309 CHEBI:45863 ! has exposure stimulus paclitaxel

[Term]
id: ECTO:9000389
name: exposure to candesartan
def: "An exposure to candesartan." []
synonym: "candesartan exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3347 ! has exposure stimulus candesartan
relationship: RO:0002309 CHEBI:3347 ! has exposure stimulus candesartan

[Term]
id: ECTO:9000390
name: exposure to fenofibrate
def: "An exposure to fenofibrate." []
synonym: "fenofibrate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5001 ! has exposure stimulus fenofibrate
relationship: RO:0002309 CHEBI:5001 ! has exposure stimulus fenofibrate

[Term]
id: ECTO:9000391
name: exposure to metformin
def: "An exposure to metformin." []
synonym: "metformin exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6801 ! has exposure stimulus metformin
relationship: RO:0002309 CHEBI:6801 ! has exposure stimulus metformin

[Term]
id: ECTO:9000392
name: exposure to ribavirin
def: "An exposure to ribavirin." []
synonym: "ribavirin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63580 ! has exposure stimulus ribavirin
relationship: RO:0002309 CHEBI:63580 ! has exposure stimulus ribavirin

[Term]
id: ECTO:9000393
name: exposure to purvalanol A
def: "An exposure to purvalanol A." []
synonym: "purvalanol A exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47600 ! has exposure stimulus purvalanol A
relationship: RO:0002309 CHEBI:47600 ! has exposure stimulus purvalanol A

[Term]
id: ECTO:9000394
name: exposure to benomyl
def: "An exposure to benomyl." []
synonym: "benomyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3015 ! has exposure stimulus benomyl
relationship: RO:0002309 CHEBI:3015 ! has exposure stimulus benomyl

[Term]
id: ECTO:9000395
name: exposure to paraquat
def: "An exposure to paraquat." []
synonym: "paraquat exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34905 ! has exposure stimulus paraquat
relationship: RO:0002309 CHEBI:34905 ! has exposure stimulus paraquat

[Term]
id: ECTO:9000396
name: exposure to camptothecin
def: "An exposure to camptothecin." []
synonym: "camptothecin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27656 ! has exposure stimulus camptothecin
relationship: RO:0002309 CHEBI:27656 ! has exposure stimulus camptothecin

[Term]
id: ECTO:9000397
name: exposure to GW 7647
def: "An exposure to GW 7647." []
synonym: "GW 7647 exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70778 ! has exposure stimulus GW 7647
relationship: RO:0002309 CHEBI:70778 ! has exposure stimulus GW 7647

[Term]
id: ECTO:9000398
name: exposure to capsazepine
def: "An exposure to capsazepine." []
synonym: "capsazepine exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70773 ! has exposure stimulus capsazepine
relationship: RO:0002309 CHEBI:70773 ! has exposure stimulus capsazepine

[Term]
id: ECTO:9000399
name: exposure to hesperadin
def: "An exposure to hesperadin." []
synonym: "hesperadin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000203 ! exposure to amine
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70726 ! has exposure stimulus hesperadin
relationship: RO:0002309 CHEBI:70726 ! has exposure stimulus hesperadin

[Term]
id: ECTO:9000400
name: exposure to reversine
def: "An exposure to reversine." []
synonym: "reversine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70723 ! has exposure stimulus reversine
relationship: RO:0002309 CHEBI:70723 ! has exposure stimulus reversine

[Term]
id: ECTO:9000401
name: exposure to carbendazim
def: "An exposure to carbendazim." []
synonym: "carbendazim exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3392 ! has exposure stimulus carbendazim
relationship: RO:0002309 CHEBI:3392 ! has exposure stimulus carbendazim

[Term]
id: ECTO:9000402
name: exposure to peptide
def: "An exposure to peptide." []
synonym: "peptide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16670 ! has exposure stimulus peptide
relationship: RO:0002309 CHEBI:16670 ! has exposure stimulus peptide

[Term]
id: ECTO:9000404
name: exposure to nitrogen
def: "An exposure to nitrogen molecular entity." []
synonym: "nitrogen molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51143 ! has exposure stimulus nitrogen molecular entity
relationship: RO:0002309 CHEBI:51143 ! has exposure stimulus nitrogen molecular entity

[Term]
id: ECTO:9000406
name: exposure to tamsulosin
def: "An exposure to tamsulosin." []
synonym: "tamsulosin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9398 ! has exposure stimulus tamsulosin
relationship: RO:0002309 CHEBI:9398 ! has exposure stimulus tamsulosin

[Term]
id: ECTO:9000407
name: exposure to ketamine
def: "An exposure to ketamine." []
synonym: "ketamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6121 ! has exposure stimulus ketamine
relationship: RO:0002309 CHEBI:6121 ! has exposure stimulus ketamine

[Term]
id: ECTO:9000408
name: exposure to L-glutamate(2-)
def: "An exposure to L-glutamate(2-)." []
synonym: "L-glutamate(2-) exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002399 ! exposure to glutamate(2-)
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29988 ! has exposure stimulus L-glutamate(2-)
relationship: RO:0002309 CHEBI:29988 ! has exposure stimulus L-glutamate(2-)

[Term]
id: ECTO:9000409
name: exposure to salt
def: "An exposure to salt." []
synonym: "salt exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24866 ! has exposure stimulus salt
relationship: RO:0002309 CHEBI:24866 ! has exposure stimulus salt

[Term]
id: ECTO:9000410
name: exposure to diethyl maleate
def: "An exposure to diethyl maleate." []
synonym: "diethyl maleate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68508 ! has exposure stimulus diethyl maleate
relationship: RO:0002309 CHEBI:68508 ! has exposure stimulus diethyl maleate

[Term]
id: ECTO:9000411
name: exposure to inositol
def: "An exposure to inositol." []
synonym: "inositol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24848 ! has exposure stimulus inositol
relationship: RO:0002309 CHEBI:24848 ! has exposure stimulus inositol

[Term]
id: ECTO:9000412
name: exposure to catechin
def: "An exposure to catechin." []
synonym: "catechin exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23053 ! has exposure stimulus catechin
relationship: RO:0002309 CHEBI:23053 ! has exposure stimulus catechin

[Term]
id: ECTO:9000413
name: exposure to strigolactone
def: "An exposure to strigolactone." []
synonym: "strigolactone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68487 ! has exposure stimulus strigolactone
relationship: RO:0002309 CHEBI:68487 ! has exposure stimulus strigolactone

[Term]
id: ECTO:9000414
name: exposure to chloroquine
def: "An exposure to chloroquine." []
synonym: "chloroquine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3638 ! has exposure stimulus chloroquine
relationship: RO:0002309 CHEBI:3638 ! has exposure stimulus chloroquine

[Term]
id: ECTO:9000415
name: exposure to imidacloprid
def: "An exposure to imidacloprid." []
synonym: "imidacloprid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5870 ! has exposure stimulus imidacloprid
relationship: RO:0002309 CHEBI:5870 ! has exposure stimulus imidacloprid

[Term]
id: ECTO:9000416
name: exposure to vanadate(3-)
def: "An exposure to vanadate(3-)." []
synonym: "vanadate(3-) exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001298 ! exposure to vanadium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46442 ! has exposure stimulus vanadate(3-)
relationship: RO:0002309 CHEBI:46442 ! has exposure stimulus vanadate(3-)

[Term]
id: ECTO:9000417
name: exposure to cyclophosphamide
def: "An exposure to cyclophosphamide." []
synonym: "cyclophosphamide exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4027 ! has exposure stimulus cyclophosphamide
relationship: RO:0002309 CHEBI:4027 ! has exposure stimulus cyclophosphamide

[Term]
id: ECTO:9000418
name: exposure to docetaxel trihydrate
def: "An exposure to docetaxel trihydrate." []
synonym: "docetaxel trihydrate exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59809 ! has exposure stimulus docetaxel trihydrate
relationship: RO:0002309 CHEBI:59809 ! has exposure stimulus docetaxel trihydrate

[Term]
id: ECTO:9000419
name: exposure to doxorubicin
def: "An exposure to doxorubicin." []
synonym: "doxorubicin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9001246 ! exposure to quinone
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002237 ! exposure to anthracycline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28748 ! has exposure stimulus doxorubicin
relationship: RO:0002309 CHEBI:28748 ! has exposure stimulus doxorubicin

[Term]
id: ECTO:9000420
name: exposure to etoposide
def: "An exposure to etoposide." []
synonym: "etoposide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000495 ! exposure to glucoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4911 ! has exposure stimulus etoposide
relationship: RO:0002309 CHEBI:4911 ! has exposure stimulus etoposide

[Term]
id: ECTO:9000421
name: exposure to 4'-epidoxorubicin
def: "An exposure to 4'-epidoxorubicin." []
synonym: "4'-epidoxorubicin exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9001246 ! exposure to quinone
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002237 ! exposure to anthracycline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47898 ! has exposure stimulus 4'-epidoxorubicin
relationship: RO:0002309 CHEBI:47898 ! has exposure stimulus 4'-epidoxorubicin

[Term]
id: ECTO:9000422
name: exposure to N-phenylthiourea
def: "An exposure to N-phenylthiourea." []
synonym: "N-phenylthiourea exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46261 ! has exposure stimulus N-phenylthiourea
relationship: RO:0002309 CHEBI:46261 ! has exposure stimulus N-phenylthiourea

[Term]
id: ECTO:9000423
name: exposure to fluoride
def: "An exposure to fluoride." []
synonym: "fluoride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17051 ! has exposure stimulus fluoride
relationship: RO:0002309 CHEBI:17051 ! has exposure stimulus fluoride

[Term]
id: ECTO:9000424
name: exposure to isobutanol
def: "An exposure to isobutanol." []
synonym: "isobutanol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46645 ! has exposure stimulus isobutanol
relationship: RO:0002309 CHEBI:46645 ! has exposure stimulus isobutanol

[Term]
id: ECTO:9000425
name: exposure to plumbagin
def: "An exposure to plumbagin." []
synonym: "plumbagin exposure" EXACT []
is_a: ECTO:9001246 ! exposure to quinone
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8273 ! has exposure stimulus plumbagin
relationship: RO:0002309 CHEBI:8273 ! has exposure stimulus plumbagin

[Term]
id: ECTO:9000426
name: exposure to alkane
def: "An exposure to alkane." []
synonym: "alkane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18310 ! has exposure stimulus alkane
relationship: RO:0002309 CHEBI:18310 ! has exposure stimulus alkane

[Term]
id: ECTO:9000427
name: exposure to nonane
def: "An exposure to nonane." []
synonym: "nonane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32892 ! has exposure stimulus nonane
relationship: RO:0002309 CHEBI:32892 ! has exposure stimulus nonane

[Term]
id: ECTO:9000428
name: exposure to decane
def: "An exposure to decane." []
synonym: "decane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41808 ! has exposure stimulus decane
relationship: RO:0002309 CHEBI:41808 ! has exposure stimulus decane

[Term]
id: ECTO:9000429
name: exposure to undecane
def: "An exposure to undecane." []
synonym: "undecane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46342 ! has exposure stimulus undecane
relationship: RO:0002309 CHEBI:46342 ! has exposure stimulus undecane

[Term]
id: ECTO:9000430
name: exposure to dodecane
def: "An exposure to dodecane." []
synonym: "dodecane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28817 ! has exposure stimulus dodecane
relationship: RO:0002309 CHEBI:28817 ! has exposure stimulus dodecane

[Term]
id: ECTO:9000431
name: exposure to isooctane
def: "An exposure to isooctane." []
synonym: "isooctane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62805 ! has exposure stimulus isooctane
relationship: RO:0002309 CHEBI:62805 ! has exposure stimulus isooctane

[Term]
id: ECTO:9000432
name: exposure to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
def: "An exposure to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one." []
synonym: "1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64598 ! has exposure stimulus 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one
relationship: RO:0002309 CHEBI:64598 ! has exposure stimulus 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one

[Term]
id: ECTO:9000433
name: exposure to polycyclic arene
def: "An exposure to polycyclic arene." []
synonym: "polycyclic arene exposure" EXACT []
is_a: ECTO:9002148 ! exposure to polycyclic hydrocarbon
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33848 ! has exposure stimulus polycyclic arene
relationship: RO:0002309 CHEBI:33848 ! has exposure stimulus polycyclic arene

[Term]
id: ECTO:9000434
name: exposure to dopamine
def: "An exposure to dopamine." []
synonym: "dopamine exposure" EXACT []
is_a: ECTO:9000319 ! exposure to catecholamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18243 ! has exposure stimulus dopamine
relationship: RO:0002309 CHEBI:18243 ! has exposure stimulus dopamine

[Term]
id: ECTO:9000435
name: exposure to bile acid
def: "An exposure to bile acid." []
synonym: "bile acid exposure" EXACT []
is_a: ECTO:9002726 ! exposure to bile acids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3098 ! has exposure stimulus bile acid
relationship: RO:0002309 CHEBI:3098 ! has exposure stimulus bile acid

[Term]
id: ECTO:9000436
name: exposure to glycoside
def: "An exposure to glycoside." []
synonym: "glycoside exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24400 ! has exposure stimulus glycoside
relationship: RO:0002309 CHEBI:24400 ! has exposure stimulus glycoside

[Term]
id: ECTO:9000437
name: exposure to lipoic acid
def: "An exposure to lipoic acid." []
synonym: "lipoic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16494 ! has exposure stimulus lipoic acid
relationship: RO:0002309 CHEBI:16494 ! has exposure stimulus lipoic acid

[Term]
id: ECTO:9000438
name: exposure to simvastatin
def: "An exposure to simvastatin." []
synonym: "simvastatin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000259 ! exposure to statin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9150 ! has exposure stimulus simvastatin
relationship: RO:0002309 CHEBI:9150 ! has exposure stimulus simvastatin

[Term]
id: ECTO:9000439
name: exposure to acetylsalicylate
def: "An exposure to acetylsalicylate." []
synonym: "acetylsalicylate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:13719 ! has exposure stimulus acetylsalicylate
relationship: RO:0002309 CHEBI:13719 ! has exposure stimulus acetylsalicylate

[Term]
id: ECTO:9000440
name: exposure to clopidogrel
def: "An exposure to clopidogrel." []
synonym: "clopidogrel exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37941 ! has exposure stimulus clopidogrel
relationship: RO:0002309 CHEBI:37941 ! has exposure stimulus clopidogrel

[Term]
id: ECTO:9000441
name: exposure to dehydroepiandrosterone
def: "An exposure to dehydroepiandrosterone." []
synonym: "dehydroepiandrosterone exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28689 ! has exposure stimulus dehydroepiandrosterone
relationship: RO:0002309 CHEBI:28689 ! has exposure stimulus dehydroepiandrosterone

[Term]
id: ECTO:9000442
name: exposure to 11-deoxycorticosterone
def: "An exposure to 11-deoxycorticosterone." []
synonym: "11-deoxycorticosterone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000294 ! exposure to mineralocorticoid
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16973 ! has exposure stimulus 11-deoxycorticosterone
relationship: RO:0002309 CHEBI:16973 ! has exposure stimulus 11-deoxycorticosterone

[Term]
id: ECTO:9000443
name: exposure to butyrate
def: "An exposure to butyrate." []
synonym: "butyrate exposure" EXACT []
is_a: ECTO:9002589 ! exposure to saturated fatty acid anion
is_a: ECTO:9002596 ! exposure to short-chain fatty acid anion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17968 ! has exposure stimulus butyrate
relationship: RO:0002309 CHEBI:17968 ! has exposure stimulus butyrate

[Term]
id: ECTO:9000444
name: exposure to L-arginine
def: "An exposure to L-arginine." []
synonym: "L-arginine exposure" EXACT []
is_a: ECTO:9002242 ! exposure to arginine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16467 ! has exposure stimulus L-arginine
relationship: RO:0002309 CHEBI:16467 ! has exposure stimulus L-arginine

[Term]
id: ECTO:9000446
name: exposure to arsenite(3-)
def: "An exposure to arsenite(3-)." []
synonym: "arsenite(3-) exposure" EXACT []
is_a: ECTO:9000447 ! exposure to arsenite ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29866 ! has exposure stimulus arsenite(3-)
relationship: RO:0002309 CHEBI:29866 ! has exposure stimulus arsenite(3-)

[Term]
id: ECTO:9000447
name: exposure to arsenite ion
def: "An exposure to arsenite ion." []
synonym: "arsenite ion exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000032 ! exposure to arsenic
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22633 ! has exposure stimulus arsenite ion
relationship: RO:0002309 CHEBI:22633 ! has exposure stimulus arsenite ion

[Term]
id: ECTO:9000449
name: exposure to cyanide
def: "An exposure to cyanide." []
synonym: "cyanide exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17514 ! has exposure stimulus cyanide
relationship: RO:0002309 CHEBI:17514 ! has exposure stimulus cyanide

[Term]
id: ECTO:9000450
name: exposure to sodium arsenite
def: "An exposure to sodium arsenite." []
synonym: "sodium arsenite exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000032 ! exposure to arsenic
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29678 ! has exposure stimulus sodium arsenite
relationship: RO:0002309 CHEBI:29678 ! has exposure stimulus sodium arsenite

[Term]
id: ECTO:9000451
name: exposure to acrylamide
def: "An exposure to acrylamide." []
synonym: "acrylamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28619 ! has exposure stimulus acrylamide
relationship: RO:0002309 CHEBI:28619 ! has exposure stimulus acrylamide

[Term]
id: ECTO:9000452
name: exposure to latrunculin B
def: "An exposure to latrunculin B." []
synonym: "latrunculin B exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49703 ! has exposure stimulus latrunculin B
relationship: RO:0002309 CHEBI:49703 ! has exposure stimulus latrunculin B

[Term]
id: ECTO:9000453
name: exposure to micafungin
def: "An exposure to micafungin." []
synonym: "micafungin exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:600520 ! has exposure stimulus micafungin
relationship: RO:0002309 CHEBI:600520 ! has exposure stimulus micafungin

[Term]
id: ECTO:9000454
name: exposure to monosodium glutamate
def: "An exposure to monosodium glutamate." []
synonym: "monosodium glutamate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64220 ! has exposure stimulus monosodium glutamate
relationship: RO:0002309 CHEBI:64220 ! has exposure stimulus monosodium glutamate

[Term]
id: ECTO:9000455
name: exposure to Aroclor 1254
def: "An exposure to Aroclor 1254." []
synonym: "Aroclor 1254 exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63933 ! has exposure stimulus Aroclor 1254
relationship: RO:0002309 CHEBI:63933 ! has exposure stimulus Aroclor 1254

[Term]
id: ECTO:9000456
name: exposure to serotonin
def: "An exposure to serotonin." []
synonym: "serotonin exposure" EXACT []
is_a: ECTO:9000318 ! exposure to monoamine
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28790 ! has exposure stimulus serotonin
relationship: RO:0002309 CHEBI:28790 ! has exposure stimulus serotonin

[Term]
id: ECTO:9000457
name: exposure to Thyroglobulin triiodothyronine
def: "An exposure to Thyroglobulin triiodothyronine." []
synonym: "Thyroglobulin triiodothyronine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80690 ! has exposure stimulus Thyroglobulin triiodothyronine
relationship: RO:0002309 CHEBI:80690 ! has exposure stimulus Thyroglobulin triiodothyronine

[Term]
id: ECTO:9000458
name: exposure to aldosterone
def: "An exposure to aldosterone." []
synonym: "aldosterone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000294 ! exposure to mineralocorticoid
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27584 ! has exposure stimulus aldosterone
relationship: RO:0002309 CHEBI:27584 ! has exposure stimulus aldosterone

[Term]
id: ECTO:9000459
name: exposure to acadesine
def: "An exposure to acadesine." []
synonym: "acadesine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28498 ! has exposure stimulus acadesine
relationship: RO:0002309 CHEBI:28498 ! has exposure stimulus acadesine

[Term]
id: ECTO:9000460
name: exposure to vasopressin
def: "An exposure to vasopressin." []
synonym: "vasopressin exposure" EXACT []
is_a: ECTO:9000273 ! exposure to peptide hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9937 ! has exposure stimulus vasopressin
relationship: RO:0002309 CHEBI:9937 ! has exposure stimulus vasopressin

[Term]
id: ECTO:9000461
name: exposure to Nonylphenol
def: "An exposure to Nonylphenol." []
synonym: "Nonylphenol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:79516 ! has exposure stimulus Nonylphenol
relationship: RO:0002309 CHEBI:79516 ! has exposure stimulus Nonylphenol

[Term]
id: ECTO:9000462
name: exposure to desipramine
def: "An exposure to desipramine." []
synonym: "desipramine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47781 ! has exposure stimulus desipramine
relationship: RO:0002309 CHEBI:47781 ! has exposure stimulus desipramine

[Term]
id: ECTO:9000463
name: exposure to cordycepin
def: "An exposure to cordycepin." []
synonym: "cordycepin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29014 ! has exposure stimulus cordycepin
relationship: RO:0002309 CHEBI:29014 ! has exposure stimulus cordycepin

[Term]
id: ECTO:9000464
name: exposure to gold(3+)
def: "An exposure to gold(3+)." []
synonym: "gold(3+) exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9000516 ! exposure to gold
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49496 ! has exposure stimulus gold(3+)
relationship: RO:0002309 CHEBI:49496 ! has exposure stimulus gold(3+)

[Term]
id: ECTO:9000465
name: exposure to methamphetamine hydrochloride
def: "An exposure to methamphetamine hydrochloride." []
synonym: "methamphetamine hydrochloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000203 ! exposure to amine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35340 ! has exposure stimulus methamphetamine hydrochloride
relationship: RO:0002309 CHEBI:35340 ! has exposure stimulus methamphetamine hydrochloride

[Term]
id: ECTO:9000466
name: exposure to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
def: "An exposure to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine." []
synonym: "2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000304 ! exposure to ammonium ion
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44811 ! has exposure stimulus 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
relationship: RO:0002309 CHEBI:44811 ! has exposure stimulus 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine

[Term]
id: ECTO:9000467
name: exposure to forskolin
def: "An exposure to forskolin." []
synonym: "forskolin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42471 ! has exposure stimulus forskolin
relationship: RO:0002309 CHEBI:42471 ! has exposure stimulus forskolin

[Term]
id: ECTO:9000468
name: exposure to kainic acid
def: "An exposure to kainic acid." []
synonym: "kainic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31746 ! has exposure stimulus kainic acid
relationship: RO:0002309 CHEBI:31746 ! has exposure stimulus kainic acid

[Term]
id: ECTO:9000469
name: exposure to sodium phosphate
def: "An exposure to sodium phosphate." []
synonym: "sodium phosphate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9002802 ! exposure to inorganic phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37586 ! has exposure stimulus sodium phosphate
relationship: RO:0002309 CHEBI:37586 ! has exposure stimulus sodium phosphate

[Term]
id: ECTO:9000470
name: exposure to L-phenylalanine derivative
def: "An exposure to L-phenylalanine derivative." []
synonym: "L-phenylalanine derivative exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84144 ! has exposure stimulus L-phenylalanine derivative
relationship: RO:0002309 CHEBI:84144 ! has exposure stimulus L-phenylalanine derivative

[Term]
id: ECTO:9000471
name: exposure to Thyroid stimulating hormone
def: "An exposure to thyroid stimulating hormone." []
synonym: "thyroid stimulating hormone exposure" EXACT []
is_a: ECTO:9000487 ! exposure to glycoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81567 ! has exposure stimulus thyroid stimulating hormone
relationship: RO:0002309 CHEBI:81567 ! has exposure stimulus thyroid stimulating hormone

[Term]
id: ECTO:9000472
name: exposure to nocodazole
def: "An exposure to nocodazole." []
synonym: "nocodazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34892 ! has exposure stimulus nocodazole
relationship: RO:0002309 CHEBI:34892 ! has exposure stimulus nocodazole

[Term]
id: ECTO:9000474
name: exposure to D-galactosamine
def: "An exposure to D-galactosamine." []
synonym: "D-galactosamine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28328 ! has exposure stimulus D-galactosamine
relationship: RO:0002309 CHEBI:28328 ! has exposure stimulus D-galactosamine

[Term]
id: ECTO:9000475
name: exposure to L-dopa
def: "An exposure to L-dopa." []
synonym: "L-dopa exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9000470 ! exposure to L-phenylalanine derivative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15765 ! has exposure stimulus L-dopa
relationship: RO:0002309 CHEBI:15765 ! has exposure stimulus L-dopa

[Term]
id: ECTO:9000476
name: exposure to tetrahydrofolate
def: "An exposure to tetrahydrofolate." []
synonym: "tetrahydrofolate exposure" EXACT []
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67016 ! has exposure stimulus tetrahydrofolate
relationship: RO:0002309 CHEBI:67016 ! has exposure stimulus tetrahydrofolate

[Term]
id: ECTO:9000477
name: exposure to 17alpha-ethynylestradiol
def: "An exposure to 17alpha-ethynylestradiol." []
synonym: "17alpha-ethynylestradiol exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4903 ! has exposure stimulus 17alpha-ethynylestradiol
relationship: RO:0002309 CHEBI:4903 ! has exposure stimulus 17alpha-ethynylestradiol

[Term]
id: ECTO:9000478
name: exposure to arachidonic acid
def: "An exposure to arachidonic acid." []
synonym: "arachidonic acid exposure" EXACT []
is_a: ECTO:9002507 ! exposure to polyunsaturated fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15843 ! has exposure stimulus arachidonic acid
relationship: RO:0002309 CHEBI:15843 ! has exposure stimulus arachidonic acid

[Term]
id: ECTO:9000479
name: exposure to dextromethorphan
def: "An exposure to dextromethorphan." []
synonym: "dextromethorphan exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000200 ! exposure to isoquinoline alkaloid
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4470 ! has exposure stimulus dextromethorphan
relationship: RO:0002309 CHEBI:4470 ! has exposure stimulus dextromethorphan

[Term]
id: ECTO:9000480
name: exposure to diphenidol
def: "An exposure to diphenidol." []
synonym: "diphenidol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4638 ! has exposure stimulus diphenidol
relationship: RO:0002309 CHEBI:4638 ! has exposure stimulus diphenidol

[Term]
id: ECTO:9000481
name: exposure to 1-oleoyl-sn-glycerol 3-phosphate
def: "An exposure to 1-oleoyl-sn-glycerol 3-phosphate." []
synonym: "1-oleoyl-sn-glycerol 3-phosphate exposure" EXACT []
is_a: ECTO:9002689 ! exposure to lysophosphatidic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62837 ! has exposure stimulus 1-oleoyl-sn-glycerol 3-phosphate
relationship: RO:0002309 CHEBI:62837 ! has exposure stimulus 1-oleoyl-sn-glycerol 3-phosphate

[Term]
id: ECTO:9000482
name: exposure to wortmannin
def: "An exposure to wortmannin." []
synonym: "wortmannin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52289 ! has exposure stimulus wortmannin
relationship: RO:0002309 CHEBI:52289 ! has exposure stimulus wortmannin

[Term]
id: ECTO:9000483
name: exposure to tunicamycin
def: "An exposure to tunicamycin." []
synonym: "tunicamycin exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29699 ! has exposure stimulus tunicamycin
relationship: RO:0002309 CHEBI:29699 ! has exposure stimulus tunicamycin

[Term]
id: ECTO:9000484
name: exposure to thapsigargin
def: "An exposure to thapsigargin." []
synonym: "thapsigargin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9516 ! has exposure stimulus thapsigargin
relationship: RO:0002309 CHEBI:9516 ! has exposure stimulus thapsigargin

[Term]
id: ECTO:9000485
name: exposure to polyamine macromolecule
def: "An exposure to polyamine macromolecule." []
synonym: "polyamine macromolecule exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51349 ! has exposure stimulus polyamine macromolecule
relationship: RO:0002309 CHEBI:51349 ! has exposure stimulus polyamine macromolecule

[Term]
id: ECTO:9000486
name: exposure to putrescine
def: "An exposure to putrescine." []
synonym: "putrescine exposure" EXACT []
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17148 ! has exposure stimulus putrescine
relationship: RO:0002309 CHEBI:17148 ! has exposure stimulus putrescine

[Term]
id: ECTO:9000487
name: exposure to glycoprotein
def: "An exposure to glycoprotein." []
synonym: "glycoprotein exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002133 ! exposure to protein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17089 ! has exposure stimulus glycoprotein
relationship: RO:0002309 CHEBI:17089 ! has exposure stimulus glycoprotein

[Term]
id: ECTO:9000488
name: exposure to monosodium L-glutamate
def: "An exposure to monosodium L-glutamate." []
synonym: "monosodium L-glutamate exposure" EXACT []
is_a: ECTO:9000454 ! exposure to monosodium glutamate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64243 ! has exposure stimulus monosodium L-glutamate
relationship: RO:0002309 CHEBI:64243 ! has exposure stimulus monosodium L-glutamate

[Term]
id: ECTO:9000489
name: exposure to 3,3',4,4',5-pentachlorobiphenyl
def: "An exposure to 3,3',4,4',5-pentachlorobiphenyl." []
synonym: "3,3',4,4',5-pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000654 ! exposure to pentachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34317 ! has exposure stimulus 3,3',4,4',5-pentachlorobiphenyl
relationship: RO:0002309 CHEBI:34317 ! has exposure stimulus 3,3',4,4',5-pentachlorobiphenyl

[Term]
id: ECTO:9000490
name: exposure to 2,3,7,8-tetrachlorodibenzodioxine
def: "An exposure to 2,3,7,8-tetrachlorodibenzodioxine." []
synonym: "2,3,7,8-tetrachlorodibenzodioxine exposure" EXACT []
is_a: ECTO:9001625 ! exposure to polychlorinated dibenzodioxine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28119 ! has exposure stimulus 2,3,7,8-tetrachlorodibenzodioxine
relationship: RO:0002309 CHEBI:28119 ! has exposure stimulus 2,3,7,8-tetrachlorodibenzodioxine

[Term]
id: ECTO:9000491
name: exposure to biphenyl
def: "An exposure to biphenyl." []
synonym: "biphenyl exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17097 ! has exposure stimulus biphenyl
relationship: RO:0002309 CHEBI:17097 ! has exposure stimulus biphenyl

[Term]
id: ECTO:9000492
name: exposure to dimethyl sulfoxide
def: "An exposure to dimethyl sulfoxide." []
synonym: "dimethyl sulfoxide exposure" EXACT []
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28262 ! has exposure stimulus dimethyl sulfoxide
relationship: RO:0002309 CHEBI:28262 ! has exposure stimulus dimethyl sulfoxide

[Term]
id: ECTO:9000493
name: exposure to phorbol 13-acetate 12-myristate
def: "An exposure to phorbol 13-acetate 12-myristate." []
synonym: "phorbol 13-acetate 12-myristate exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37537 ! has exposure stimulus phorbol 13-acetate 12-myristate
relationship: RO:0002309 CHEBI:37537 ! has exposure stimulus phorbol 13-acetate 12-myristate

[Term]
id: ECTO:9000494
name: exposure to diterpene
def: "An exposure to diterpene." []
synonym: "diterpene exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35190 ! has exposure stimulus diterpene
relationship: RO:0002309 CHEBI:35190 ! has exposure stimulus diterpene

[Term]
id: ECTO:9000495
name: exposure to glucoside
def: "An exposure to glucoside." []
synonym: "glucoside exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24278 ! has exposure stimulus glucoside
relationship: RO:0002309 CHEBI:24278 ! has exposure stimulus glucoside

[Term]
id: ECTO:9000496
name: exposure to ionomycin
def: "An exposure to ionomycin." []
synonym: "ionomycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002507 ! exposure to polyunsaturated fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63954 ! has exposure stimulus ionomycin
relationship: RO:0002309 CHEBI:63954 ! has exposure stimulus ionomycin

[Term]
id: ECTO:9000497
name: exposure to resveratrol
def: "An exposure to resveratrol." []
synonym: "resveratrol exposure" EXACT []
is_a: ECTO:9000251 ! exposure to stilbenoid
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27881 ! has exposure stimulus resveratrol
relationship: RO:0002309 CHEBI:27881 ! has exposure stimulus resveratrol

[Term]
id: ECTO:9000498
name: exposure to methionine
def: "An exposure to methionine." []
synonym: "methionine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16811 ! has exposure stimulus methionine
relationship: RO:0002309 CHEBI:16811 ! has exposure stimulus methionine

[Term]
id: ECTO:9000499
name: exposure to dinitrophenol
def: "An exposure to dinitrophenol." []
synonym: "dinitrophenol exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39352 ! has exposure stimulus dinitrophenol
relationship: RO:0002309 CHEBI:39352 ! has exposure stimulus dinitrophenol

[Term]
id: ECTO:9000500
name: exposure to curcumin
def: "An exposure to curcumin." []
synonym: "curcumin exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3962 ! has exposure stimulus curcumin
relationship: RO:0002309 CHEBI:3962 ! has exposure stimulus curcumin

[Term]
id: ECTO:9000501
name: exposure to beta-amyloid
def: "An exposure to amyloid-beta." []
synonym: "amyloid-beta exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64645 ! has exposure stimulus amyloid-beta
relationship: RO:0002309 CHEBI:64645 ! has exposure stimulus amyloid-beta

[Term]
id: ECTO:9000502
name: exposure to rotenone
def: "An exposure to rotenone." []
synonym: "rotenone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28201 ! has exposure stimulus rotenone
relationship: RO:0002309 CHEBI:28201 ! has exposure stimulus rotenone

[Term]
id: ECTO:9000503
name: exposure to 3-methylcholanthrene
def: "An exposure to 3-methylcholanthrene." []
synonym: "3-methylcholanthrene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34342 ! has exposure stimulus 3-methylcholanthrene
relationship: RO:0002309 CHEBI:34342 ! has exposure stimulus 3-methylcholanthrene

[Term]
id: ECTO:9000505
name: exposure to latrunculin A
def: "An exposure to latrunculin A." []
synonym: "latrunculin A exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:69136 ! has exposure stimulus latrunculin A
relationship: RO:0002309 CHEBI:69136 ! has exposure stimulus latrunculin A

[Term]
id: ECTO:9000507
name: exposure to L-glutamine
def: "An exposure to L-glutamine." []
synonym: "L-glutamine exposure" EXACT []
is_a: ECTO:9002797 ! exposure to glutamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18050 ! has exposure stimulus L-glutamine
relationship: RO:0002309 CHEBI:18050 ! has exposure stimulus L-glutamine

[Term]
id: ECTO:9000508
name: exposure to hydrogen sulfide
def: "An exposure to hydrogen sulfide." []
synonym: "hydrogen sulfide exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16136 ! has exposure stimulus hydrogen sulfide
relationship: RO:0002309 CHEBI:16136 ! has exposure stimulus hydrogen sulfide

[Term]
id: ECTO:9000509
name: exposure to palmitoleic acid
def: "An exposure to palmitoleic acid." []
synonym: "palmitoleic acid exposure" EXACT []
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28716 ! has exposure stimulus palmitoleic acid
relationship: RO:0002309 CHEBI:28716 ! has exposure stimulus palmitoleic acid

[Term]
id: ECTO:9000510
name: exposure to bleomycin
def: "An exposure to bleomycin." []
synonym: "bleomycin exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22907 ! has exposure stimulus bleomycin
relationship: RO:0002309 CHEBI:22907 ! has exposure stimulus bleomycin

[Term]
id: ECTO:9000511
name: exposure to diosgenin
def: "An exposure to diosgenin." []
synonym: "diosgenin exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000264 ! exposure to sterol
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4629 ! has exposure stimulus diosgenin
relationship: RO:0002309 CHEBI:4629 ! has exposure stimulus diosgenin

[Term]
id: ECTO:9000512
name: exposure to haloperidol
def: "An exposure to haloperidol." []
synonym: "haloperidol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5613 ! has exposure stimulus haloperidol
relationship: RO:0002309 CHEBI:5613 ! has exposure stimulus haloperidol

[Term]
id: ECTO:9000513
name: exposure to acetylcholine
def: "An exposure to acetylcholine." []
synonym: "acetylcholine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000304 ! exposure to ammonium ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15355 ! has exposure stimulus acetylcholine
relationship: RO:0002309 CHEBI:15355 ! has exposure stimulus acetylcholine

[Term]
id: ECTO:9000514
name: exposure to temozolomide
def: "An exposure to temozolomide." []
synonym: "temozolomide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72564 ! has exposure stimulus temozolomide
relationship: RO:0002309 CHEBI:72564 ! has exposure stimulus temozolomide

[Term]
id: ECTO:9000516
name: exposure to gold
def: "An exposure to gold molecular entity." []
synonym: "gold molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33969 ! has exposure stimulus gold molecular entity
relationship: RO:0002309 CHEBI:33969 ! has exposure stimulus gold molecular entity

[Term]
id: ECTO:9000517
name: exposure to angiotensin
def: "An exposure to angiotensin." []
synonym: "angiotensin exposure" EXACT []
is_a: ECTO:9000273 ! exposure to peptide hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48433 ! has exposure stimulus angiotensin
relationship: RO:0002309 CHEBI:48433 ! has exposure stimulus angiotensin

[Term]
id: ECTO:9000518
name: exposure to double-stranded DNA
def: "An exposure to double-stranded DNA." []
synonym: "double-stranded DNA exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4705 ! has exposure stimulus double-stranded DNA
relationship: RO:0002309 CHEBI:4705 ! has exposure stimulus double-stranded DNA

[Term]
id: ECTO:9000519
name: exposure to dioxygen
def: "An exposure to dioxygen." []
synonym: "dioxygen exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15379 ! has exposure stimulus dioxygen
relationship: RO:0002309 CHEBI:15379 ! has exposure stimulus dioxygen

[Term]
id: ECTO:9000521
name: exposure to atrazine
def: "An exposure to atrazine." []
synonym: "atrazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15930 ! has exposure stimulus atrazine
relationship: RO:0002309 CHEBI:15930 ! has exposure stimulus atrazine

[Term]
id: ECTO:9000522
name: exposure to phthalate
def: "An exposure to phthalate." []
synonym: "phthalate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26092 ! has exposure stimulus phthalate
relationship: RO:0002309 CHEBI:26092 ! has exposure stimulus phthalate

[Term]
id: ECTO:9000524
name: exposure to chlorobenzene
def: "An exposure to chlorobenzene." []
synonym: "chlorobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28097 ! has exposure stimulus chlorobenzene
relationship: RO:0002309 CHEBI:28097 ! has exposure stimulus chlorobenzene

[Term]
id: ECTO:9000527
name: exposure to nitrobenzene
def: "An exposure to nitrobenzene." []
synonym: "nitrobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27798 ! has exposure stimulus nitrobenzene
relationship: RO:0002309 CHEBI:27798 ! has exposure stimulus nitrobenzene

[Term]
id: ECTO:9000528
name: obsolete styrene exposure
is_obsolete: true
replaced_by: ECTO:9000069

[Term]
id: ECTO:9000529
name: obsolete tetrachloroethene exposure
is_obsolete: true
replaced_by: ECTO:9000074

[Term]
id: ECTO:9000530
name: exposure to trichloroethene
def: "An exposure to trichloroethene." []
synonym: "trichloroethene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16602 ! has exposure stimulus trichloroethene
relationship: RO:0002309 CHEBI:16602 ! has exposure stimulus trichloroethene

[Term]
id: ECTO:9000531
name: exposure to o-xylene
def: "An exposure to o-xylene." []
synonym: "o-xylene exposure" EXACT []
is_a: ECTO:9000035 ! exposure to xylene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28063 ! has exposure stimulus o-xylene
relationship: RO:0002309 CHEBI:28063 ! has exposure stimulus o-xylene

[Term]
id: ECTO:9000532
name: exposure to thiocyanate
def: "An exposure to thiocyanate." []
synonym: "thiocyanate exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18022 ! has exposure stimulus thiocyanate
relationship: RO:0002309 CHEBI:18022 ! has exposure stimulus thiocyanate

[Term]
id: ECTO:9000533
name: exposure to organofluorine compound
def: "An exposure to organofluorine compound." []
synonym: "organofluorine compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9001124 ! exposure to fluorine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37143 ! has exposure stimulus organofluorine compound
relationship: RO:0002309 CHEBI:37143 ! has exposure stimulus organofluorine compound

[Term]
id: ECTO:9000534
name: exposure to organoarsenic compound
def: "An exposure to organoarsenic compound." []
synonym: "organoarsenic compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000032 ! exposure to arsenic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33406 ! has exposure stimulus organoarsenic compound
relationship: RO:0002309 CHEBI:33406 ! has exposure stimulus organoarsenic compound

[Term]
id: ECTO:9000535
name: obsolete polychlorobiphenyl exposure
is_obsolete: true
replaced_by: ECTO:9000068

[Term]
id: ECTO:9000537
name: exposure to ciprofloxacin
def: "An exposure to ciprofloxacin." []
synonym: "ciprofloxacin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002374 ! exposure to fluoroquinolone antibiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:100241 ! has exposure stimulus ciprofloxacin
relationship: RO:0002309 CHEBI:100241 ! has exposure stimulus ciprofloxacin

[Term]
id: ECTO:9000538
name: exposure to norfloxacin
def: "An exposure to norfloxacin." []
synonym: "norfloxacin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002374 ! exposure to fluoroquinolone antibiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:100246 ! has exposure stimulus norfloxacin
relationship: RO:0002309 CHEBI:100246 ! has exposure stimulus norfloxacin

[Term]
id: ECTO:9000539
name: exposure to thiopental
def: "An exposure to thiopental." []
synonym: "thiopental exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:102166 ! has exposure stimulus thiopental
relationship: RO:0002309 CHEBI:102166 ! has exposure stimulus thiopental

[Term]
id: ECTO:9000540
name: exposure to sulfamethazine
def: "An exposure to sulfamethazine." []
synonym: "sulfamethazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:102265 ! has exposure stimulus sulfamethazine
relationship: RO:0002309 CHEBI:102265 ! has exposure stimulus sulfamethazine

[Term]
id: ECTO:9000541
name: exposure to 1-(3-chlorophenyl)piperazine
def: "An exposure to 1-(3-chlorophenyl)piperazine." []
synonym: "1-(3-chlorophenyl)piperazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10588 ! has exposure stimulus 1-(3-chlorophenyl)piperazine
relationship: RO:0002309 CHEBI:10588 ! has exposure stimulus 1-(3-chlorophenyl)piperazine

[Term]
id: ECTO:9000542
name: exposure to metoclopramide
def: "An exposure to metoclopramide." []
synonym: "metoclopramide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:107736 ! has exposure stimulus metoclopramide
relationship: RO:0002309 CHEBI:107736 ! has exposure stimulus metoclopramide

[Term]
id: ECTO:9000543
name: exposure to 2-hydroxybenzothiazole
def: "An exposure to 2-hydroxybenzothiazole." []
synonym: "2-hydroxybenzothiazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:115196 ! has exposure stimulus 2-hydroxybenzothiazole
relationship: RO:0002309 CHEBI:115196 ! has exposure stimulus 2-hydroxybenzothiazole

[Term]
id: ECTO:9000544
name: exposure to diuron
def: "An exposure to diuron." []
synonym: "diuron exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:116509 ! has exposure stimulus diuron
relationship: RO:0002309 CHEBI:116509 ! has exposure stimulus diuron

[Term]
id: ECTO:9000545
name: exposure to atomoxetine
def: "An exposure to atomoxetine." []
synonym: "atomoxetine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:127342 ! has exposure stimulus atomoxetine
relationship: RO:0002309 CHEBI:127342 ! has exposure stimulus atomoxetine

[Term]
id: ECTO:9000546
name: exposure to sulfapyridine
def: "An exposure to sulfapyridine." []
synonym: "sulfapyridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132842 ! has exposure stimulus sulfapyridine
relationship: RO:0002309 CHEBI:132842 ! has exposure stimulus sulfapyridine

[Term]
id: ECTO:9000547
name: exposure to 3,3',4,4'-tetrachlorobiphenyl
def: "An exposure to 3,3',4,4'-tetrachlorobiphenyl." []
synonym: "3,3',4,4'-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:1367 ! has exposure stimulus 3,3',4,4'-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:1367 ! has exposure stimulus 3,3',4,4'-tetrachlorobiphenyl

[Term]
id: ECTO:9000548
name: exposure to (-)-ephedrine
def: "An exposure to (-)-ephedrine." []
synonym: "(-)-ephedrine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15407 ! has exposure stimulus (-)-ephedrine
relationship: RO:0002309 CHEBI:15407 ! has exposure stimulus (-)-ephedrine

[Term]
id: ECTO:9000549
name: exposure to cyclohexylsulfamic acid
def: "An exposure to cyclohexylsulfamic acid." []
synonym: "cyclohexylsulfamic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15964 ! has exposure stimulus cyclohexylsulfamic acid
relationship: RO:0002309 CHEBI:15964 ! has exposure stimulus cyclohexylsulfamic acid

[Term]
id: ECTO:9000550
name: exposure to aminophenazone
def: "An exposure to aminophenazone." []
synonym: "aminophenazone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:160246 ! has exposure stimulus aminophenazone
relationship: RO:0002309 CHEBI:160246 ! has exposure stimulus aminophenazone

[Term]
id: ECTO:9000551
name: exposure to pyridine
def: "An exposure to pyridine." []
synonym: "pyridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16227 ! has exposure stimulus pyridine
relationship: RO:0002309 CHEBI:16227 ! has exposure stimulus pyridine

[Term]
id: ECTO:9000552
name: exposure to naphthalene
def: "An exposure to naphthalene." []
synonym: "naphthalene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16482 ! has exposure stimulus naphthalene
relationship: RO:0002309 CHEBI:16482 ! has exposure stimulus naphthalene

[Term]
id: ECTO:9000553
name: exposure to chlordecone
def: "An exposure to chlordecone." []
synonym: "chlordecone exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16548 ! has exposure stimulus chlordecone
relationship: RO:0002309 CHEBI:16548 ! has exposure stimulus chlordecone

[Term]
id: ECTO:9000554
name: exposure to DDE
def: "An exposure to DDE." []
synonym: "DDE exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16598 ! has exposure stimulus DDE
relationship: RO:0002309 CHEBI:16598 ! has exposure stimulus DDE

[Term]
id: ECTO:9000555
name: exposure to benzo[d]isothiazol-3-one
def: "An exposure to benzo[d]isothiazol-3-one." []
synonym: "benzo[d]isothiazol-3-one exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:167099 ! has exposure stimulus benzo[d]isothiazol-3-one
relationship: RO:0002309 CHEBI:167099 ! has exposure stimulus benzo[d]isothiazol-3-one

[Term]
id: ECTO:9000556
name: exposure to codeine
def: "An exposure to codeine." []
synonym: "codeine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000200 ! exposure to isoquinoline alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16714 ! has exposure stimulus codeine
relationship: RO:0002309 CHEBI:16714 ! has exposure stimulus codeine

[Term]
id: ECTO:9000557
name: exposure to mycophenolic acid
def: "An exposure to mycophenolic acid." []
synonym: "mycophenolic acid exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:168396 ! has exposure stimulus mycophenolic acid
relationship: RO:0002309 CHEBI:168396 ! has exposure stimulus mycophenolic acid

[Term]
id: ECTO:9000558
name: exposure to biphenyl-2-ol
def: "An exposure to biphenyl-2-ol." []
synonym: "biphenyl-2-ol exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17043 ! has exposure stimulus biphenyl-2-ol
relationship: RO:0002309 CHEBI:17043 ! has exposure stimulus biphenyl-2-ol

[Term]
id: ECTO:9000559
name: exposure to 3,5-dibromo-4-hydroxybenzonitrile
def: "An exposure to 3,5-dibromo-4-hydroxybenzonitrile." []
synonym: "3,5-dibromo-4-hydroxybenzonitrile exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17192 ! has exposure stimulus 3,5-dibromo-4-hydroxybenzonitrile
relationship: RO:0002309 CHEBI:17192 ! has exposure stimulus 3,5-dibromo-4-hydroxybenzonitrile

[Term]
id: ECTO:9000560
name: exposure to tylosin
def: "An exposure to tylosin." []
synonym: "tylosin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17658 ! has exposure stimulus tylosin
relationship: RO:0002309 CHEBI:17658 ! has exposure stimulus tylosin

[Term]
id: ECTO:9000561
name: exposure to propachlor
def: "An exposure to propachlor." []
synonym: "propachlor exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:19503 ! has exposure stimulus propachlor
relationship: RO:0002309 CHEBI:19503 ! has exposure stimulus propachlor

[Term]
id: ECTO:9000562
name: exposure to ametryn
def: "An exposure to ametryn." []
synonym: "ametryn exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002558 ! exposure to polyamine
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22472 ! has exposure stimulus ametryn
relationship: RO:0002309 CHEBI:22472 ! has exposure stimulus ametryn

[Term]
id: ECTO:9000563
name: exposure to acetochlor
def: "An exposure to acetochlor." []
synonym: "acetochlor exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2394 ! has exposure stimulus acetochlor
relationship: RO:0002309 CHEBI:2394 ! has exposure stimulus acetochlor

[Term]
id: ECTO:9000564
name: exposure to alachlor
def: "An exposure to alachlor." []
synonym: "alachlor exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2533 ! has exposure stimulus alachlor
relationship: RO:0002309 CHEBI:2533 ! has exposure stimulus alachlor

[Term]
id: ECTO:9000565
name: exposure to albuterol
def: "An exposure to albuterol." []
synonym: "albuterol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2549 ! has exposure stimulus albuterol
relationship: RO:0002309 CHEBI:2549 ! has exposure stimulus albuterol

[Term]
id: ECTO:9000566
name: exposure to aldrin
def: "An exposure to aldrin." []
synonym: "aldrin exposure" EXACT []
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2564 ! has exposure stimulus aldrin
relationship: RO:0002309 CHEBI:2564 ! has exposure stimulus aldrin

[Term]
id: ECTO:9000567
name: exposure to prometryn
def: "An exposure to prometryn." []
synonym: "prometryn exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002558 ! exposure to polyamine
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26276 ! has exposure stimulus prometryn
relationship: RO:0002309 CHEBI:26276 ! has exposure stimulus prometryn

[Term]
id: ECTO:9000568
name: exposure to amitraz
def: "An exposure to amitraz." []
synonym: "amitraz exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2665 ! has exposure stimulus amitraz
relationship: RO:0002309 CHEBI:2665 ! has exposure stimulus amitraz

[Term]
id: ECTO:9000569
name: exposure to amitriptyline
def: "An exposure to amitriptyline." []
synonym: "amitriptyline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2666 ! has exposure stimulus amitriptyline
relationship: RO:0002309 CHEBI:2666 ! has exposure stimulus amitriptyline

[Term]
id: ECTO:9000570
name: exposure to 1-chloro-2,2-bis(4'-chlorophenyl)ethylene
def: "An exposure to 1-chloro-2,2-bis(4'-chlorophenyl)ethylene." []
synonym: "1-chloro-2,2-bis(4'-chlorophenyl)ethylene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27454 ! has exposure stimulus 1-chloro-2,2-bis(4'-chlorophenyl)ethylene
relationship: RO:0002309 CHEBI:27454 ! has exposure stimulus 1-chloro-2,2-bis(4'-chlorophenyl)ethylene

[Term]
id: ECTO:9000571
name: exposure to simazine
def: "An exposure to simazine." []
synonym: "simazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27496 ! has exposure stimulus simazine
relationship: RO:0002309 CHEBI:27496 ! has exposure stimulus simazine

[Term]
id: ECTO:9000572
name: exposure to 4-aminobenzenesulfonic acid
def: "An exposure to 4-aminobenzenesulfonic acid." []
synonym: "4-aminobenzenesulfonic acid exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27500 ! has exposure stimulus 4-aminobenzenesulfonic acid
relationship: RO:0002309 CHEBI:27500 ! has exposure stimulus 4-aminobenzenesulfonic acid

[Term]
id: ECTO:9000573
name: exposure to erythromycin B
def: "An exposure to erythromycin B." []
synonym: "erythromycin B exposure" EXACT []
is_a: ECTO:9000361 ! exposure to erythromycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28196 ! has exposure stimulus erythromycin B
relationship: RO:0002309 CHEBI:28196 ! has exposure stimulus erythromycin B

[Term]
id: ECTO:9000574
name: exposure to erythromycin E
def: "An exposure to erythromycin E." []
synonym: "erythromycin E exposure" EXACT []
is_a: ECTO:9000361 ! exposure to erythromycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28239 ! has exposure stimulus erythromycin E
relationship: RO:0002309 CHEBI:28239 ! has exposure stimulus erythromycin E

[Term]
id: ECTO:9000575
name: exposure to erythromycin D
def: "An exposure to erythromycin D." []
synonym: "erythromycin D exposure" EXACT []
is_a: ECTO:9000361 ! exposure to erythromycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28331 ! has exposure stimulus erythromycin D
relationship: RO:0002309 CHEBI:28331 ! has exposure stimulus erythromycin D

[Term]
id: ECTO:9000576
name: exposure to beta-hexachlorocyclohexane
def: "An exposure to beta-hexachlorocyclohexane." []
synonym: "beta-hexachlorocyclohexane exposure" EXACT []
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
is_a: ECTO:9002415 ! exposure to hexachlorocyclohexane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28428 ! has exposure stimulus beta-hexachlorocyclohexane
relationship: RO:0002309 CHEBI:28428 ! has exposure stimulus beta-hexachlorocyclohexane

[Term]
id: ECTO:9000577
name: exposure to reserpine
def: "An exposure to reserpine." []
synonym: "reserpine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28487 ! has exposure stimulus reserpine
relationship: RO:0002309 CHEBI:28487 ! has exposure stimulus reserpine

[Term]
id: ECTO:9000578
name: exposure to aspartame
def: "An exposure to aspartame." []
synonym: "aspartame exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2877 ! has exposure stimulus aspartame
relationship: RO:0002309 CHEBI:2877 ! has exposure stimulus aspartame

[Term]
id: ECTO:9000579
name: exposure to phenanthrene
def: "An exposure to phenanthrene." []
synonym: "phenanthrene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28851 ! has exposure stimulus phenanthrene
relationship: RO:0002309 CHEBI:28851 ! has exposure stimulus phenanthrene

[Term]
id: ECTO:9000580
name: exposure to 2,4-D
def: "An exposure to 2,4-D." []
synonym: "2,4-D exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28854 ! has exposure stimulus 2,4-D
relationship: RO:0002309 CHEBI:28854 ! has exposure stimulus 2,4-D

[Term]
id: ECTO:9000581
name: exposure to atenolol
def: "An exposure to atenolol." []
synonym: "atenolol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2904 ! has exposure stimulus atenolol
relationship: RO:0002309 CHEBI:2904 ! has exposure stimulus atenolol

[Term]
id: ECTO:9000582
name: exposure to atorvastatin calcium trihydrate
def: "An exposure to atorvastatin calcium trihydrate." []
synonym: "atorvastatin calcium trihydrate exposure" EXACT []
is_a: ECTO:9000259 ! exposure to statin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2911 ! has exposure stimulus atorvastatin calcium trihydrate
relationship: RO:0002309 CHEBI:2911 ! has exposure stimulus atorvastatin calcium trihydrate

[Term]
id: ECTO:9000583
name: exposure to azithromycin
def: "An exposure to azithromycin." []
synonym: "azithromycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2955 ! has exposure stimulus azithromycin
relationship: RO:0002309 CHEBI:2955 ! has exposure stimulus azithromycin

[Term]
id: ECTO:9000584
name: exposure to kresoxim-methyl
def: "An exposure to kresoxim-methyl." []
synonym: "kresoxim-methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2962 ! has exposure stimulus kresoxim-methyl
relationship: RO:0002309 CHEBI:2962 ! has exposure stimulus kresoxim-methyl

[Term]
id: ECTO:9000585
name: exposure to bentazone
def: "An exposure to bentazone." []
synonym: "bentazone exposure" EXACT []
is_a: ECTO:9002635 ! exposure to thiazide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3018 ! has exposure stimulus bentazone
relationship: RO:0002309 CHEBI:3018 ! has exposure stimulus bentazone

[Term]
id: ECTO:9000586
name: exposure to terbutylazine
def: "An exposure to terbutylazine." []
synonym: "terbutylazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30263 ! has exposure stimulus terbutylazine
relationship: RO:0002309 CHEBI:30263 ! has exposure stimulus terbutylazine

[Term]
id: ECTO:9000587
name: exposure to simeton
def: "An exposure to simeton." []
synonym: "simeton exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30264 ! has exposure stimulus simeton
relationship: RO:0002309 CHEBI:30264 ! has exposure stimulus simeton

[Term]
id: ECTO:9000588
name: exposure to naphthalene-2,7-disulfonic acid
def: "An exposure to naphthalene-2,7-disulfonic acid." []
synonym: "naphthalene-2,7-disulfonic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30898 ! has exposure stimulus naphthalene-2,7-disulfonic acid
relationship: RO:0002309 CHEBI:30898 ! has exposure stimulus naphthalene-2,7-disulfonic acid

[Term]
id: ECTO:9000589
name: exposure to bicalutamide
def: "An exposure to bicalutamide." []
synonym: "bicalutamide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3090 ! has exposure stimulus bicalutamide
relationship: RO:0002309 CHEBI:3090 ! has exposure stimulus bicalutamide

[Term]
id: ECTO:9000590
name: exposure to antipyrine
def: "An exposure to antipyrine." []
synonym: "antipyrine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31225 ! has exposure stimulus antipyrine
relationship: RO:0002309 CHEBI:31225 ! has exposure stimulus antipyrine

[Term]
id: ECTO:9000591
name: exposure to esatenolol
def: "An exposure to esatenolol." []
synonym: "esatenolol exposure" EXACT []
is_a: ECTO:9000581 ! exposure to atenolol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31556 ! has exposure stimulus esatenolol
relationship: RO:0002309 CHEBI:31556 ! has exposure stimulus esatenolol

[Term]
id: ECTO:9000592
name: exposure to iobitridol
def: "An exposure to iobitridol." []
synonym: "iobitridol exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31701 ! has exposure stimulus iobitridol
relationship: RO:0002309 CHEBI:31701 ! has exposure stimulus iobitridol

[Term]
id: ECTO:9000593
name: exposure to iohexol
def: "An exposure to iohexol." []
synonym: "iohexol exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31709 ! has exposure stimulus iohexol
relationship: RO:0002309 CHEBI:31709 ! has exposure stimulus iohexol

[Term]
id: ECTO:9000594
name: exposure to iomeprol
def: "An exposure to iomeprol." []
synonym: "iomeprol exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31710 ! has exposure stimulus iomeprol
relationship: RO:0002309 CHEBI:31710 ! has exposure stimulus iomeprol

[Term]
id: ECTO:9000595
name: exposure to iopamidol
def: "An exposure to iopamidol." []
synonym: "iopamidol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31711 ! has exposure stimulus iopamidol
relationship: RO:0002309 CHEBI:31711 ! has exposure stimulus iopamidol

[Term]
id: ECTO:9000596
name: exposure to bromacil
def: "An exposure to bromacil." []
synonym: "bromacil exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3177 ! has exposure stimulus bromacil
relationship: RO:0002309 CHEBI:3177 ! has exposure stimulus bromacil

[Term]
id: ECTO:9000597
name: exposure to saccharin
def: "An exposure to saccharin." []
synonym: "saccharin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32111 ! has exposure stimulus saccharin
relationship: RO:0002309 CHEBI:32111 ! has exposure stimulus saccharin

[Term]
id: ECTO:9000598
name: exposure to sucralose
def: "An exposure to sucralose." []
synonym: "sucralose exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32159 ! has exposure stimulus sucralose
relationship: RO:0002309 CHEBI:32159 ! has exposure stimulus sucralose

[Term]
id: ECTO:9000599
name: exposure to sulfadimethoxine
def: "An exposure to sulfadimethoxine." []
synonym: "sulfadimethoxine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32161 ! has exposure stimulus sulfadimethoxine
relationship: RO:0002309 CHEBI:32161 ! has exposure stimulus sulfadimethoxine

[Term]
id: ECTO:9000600
name: exposure to bupropion
def: "An exposure to bupropion." []
synonym: "bupropion exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3219 ! has exposure stimulus bupropion
relationship: RO:0002309 CHEBI:3219 ! has exposure stimulus bupropion

[Term]
id: ECTO:9000601
name: exposure to gamma-hexachlorocyclohexane
def: "An exposure to gamma-hexachlorocyclohexane." []
synonym: "gamma-hexachlorocyclohexane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000283 ! exposure to cyclodiene organochlorine insecticide
is_a: ECTO:9002415 ! exposure to hexachlorocyclohexane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32888 ! has exposure stimulus gamma-hexachlorocyclohexane
relationship: RO:0002309 CHEBI:32888 ! has exposure stimulus gamma-hexachlorocyclohexane

[Term]
id: ECTO:9000602
name: exposure to 2-nitrotoluene
def: "An exposure to 2-nitrotoluene." []
synonym: "2-nitrotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33098 ! has exposure stimulus 2-nitrotoluene
relationship: RO:0002309 CHEBI:33098 ! has exposure stimulus 2-nitrotoluene

[Term]
id: ECTO:9000603
name: exposure to carbamazepine
def: "An exposure to carbamazepine." []
synonym: "carbamazepine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3387 ! has exposure stimulus carbamazepine
relationship: RO:0002309 CHEBI:3387 ! has exposure stimulus carbamazepine

[Term]
id: ECTO:9000604
name: exposure to carbetamide
def: "An exposure to carbetamide." []
synonym: "carbetamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3394 ! has exposure stimulus carbetamide
relationship: RO:0002309 CHEBI:3394 ! has exposure stimulus carbetamide

[Term]
id: ECTO:9000605
name: exposure to 1-nitronaphthalene
def: "An exposure to 1-nitronaphthalene." []
synonym: "1-nitronaphthalene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34104 ! has exposure stimulus 1-nitronaphthalene
relationship: RO:0002309 CHEBI:34104 ! has exposure stimulus 1-nitronaphthalene

[Term]
id: ECTO:9000606
name: exposure to 2,2',3,3',5,5'-hexachlorobiphenyl
def: "An exposure to 2,2',3,3',5,5'-hexachlorobiphenyl." []
synonym: "2,2',3,3',5,5'-hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34197 ! has exposure stimulus 2,2',3,3',5,5'-hexachlorobiphenyl
relationship: RO:0002309 CHEBI:34197 ! has exposure stimulus 2,2',3,3',5,5'-hexachlorobiphenyl

[Term]
id: ECTO:9000607
name: exposure to 2,2',3,3',6,6'-hexachlorobiphenyl
def: "An exposure to 2,2',3,3',6,6'-hexachlorobiphenyl." []
synonym: "2,2',3,3',6,6'-hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34199 ! has exposure stimulus 2,2',3,3',6,6'-hexachlorobiphenyl
relationship: RO:0002309 CHEBI:34199 ! has exposure stimulus 2,2',3,3',6,6'-hexachlorobiphenyl

[Term]
id: ECTO:9000608
name: exposure to 2,2',4,4',5,5'-hexachlorobiphenyl
def: "An exposure to 2,2',4,4',5,5'-hexachlorobiphenyl." []
synonym: "2,2',4,4',5,5'-hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34202 ! has exposure stimulus 2,2',4,4',5,5'-hexachlorobiphenyl
relationship: RO:0002309 CHEBI:34202 ! has exposure stimulus 2,2',4,4',5,5'-hexachlorobiphenyl

[Term]
id: ECTO:9000609
name: exposure to 2,2',4,4',6,6'-hexachlorobiphenyl
def: "An exposure to 2,2',4,4',6,6'-hexachlorobiphenyl." []
synonym: "2,2',4,4',6,6'-hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34203 ! has exposure stimulus 2,2',4,4',6,6'-hexachlorobiphenyl
relationship: RO:0002309 CHEBI:34203 ! has exposure stimulus 2,2',4,4',6,6'-hexachlorobiphenyl

[Term]
id: ECTO:9000610
name: exposure to 2,2',4,4'-tetrachlorobiphenyl
def: "An exposure to 2,2',4,4'-tetrachlorobiphenyl." []
synonym: "2,2',4,4'-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34204 ! has exposure stimulus 2,2',4,4'-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:34204 ! has exposure stimulus 2,2',4,4'-tetrachlorobiphenyl

[Term]
id: ECTO:9000611
name: exposure to 2,2',4,5-tetrachlorobiphenyl
def: "An exposure to 2,2',4,5-tetrachlorobiphenyl." []
synonym: "2,2',4,5-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34205 ! has exposure stimulus 2,2',4,5-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:34205 ! has exposure stimulus 2,2',4,5-tetrachlorobiphenyl

[Term]
id: ECTO:9000612
name: exposure to 2,2',5,5'-tetrachlorobiphenyl
def: "An exposure to 2,2',5,5'-tetrachlorobiphenyl." []
synonym: "2,2',5,5'-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34206 ! has exposure stimulus 2,2',5,5'-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:34206 ! has exposure stimulus 2,2',5,5'-tetrachlorobiphenyl

[Term]
id: ECTO:9000613
name: exposure to 2,3',5-trichlorobiphenyl
def: "An exposure to 2,3',5-trichlorobiphenyl." []
synonym: "2,3',5-trichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000652 ! exposure to trichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34215 ! has exposure stimulus 2,3',5-trichlorobiphenyl
relationship: RO:0002309 CHEBI:34215 ! has exposure stimulus 2,3',5-trichlorobiphenyl

[Term]
id: ECTO:9000614
name: exposure to 2,3,3',4,5-pentachlorobiphenyl
def: "An exposure to 2,3,3',4,5-pentachlorobiphenyl." []
synonym: "2,3,3',4,5-pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000654 ! exposure to pentachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34216 ! has exposure stimulus 2,3,3',4,5-pentachlorobiphenyl
relationship: RO:0002309 CHEBI:34216 ! has exposure stimulus 2,3,3',4,5-pentachlorobiphenyl

[Term]
id: ECTO:9000615
name: exposure to 2,3,4,4'-tetrachlorobiphenyl
def: "An exposure to 2,3,4,4'-tetrachlorobiphenyl." []
synonym: "2,3,4,4'-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34218 ! has exposure stimulus 2,3,4,4'-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:34218 ! has exposure stimulus 2,3,4,4'-tetrachlorobiphenyl

[Term]
id: ECTO:9000616
name: exposure to 2,3,4,5,6-pentachlorobiphenyl
def: "An exposure to 2,3,4,5,6-pentachlorobiphenyl." []
synonym: "2,3,4,5,6-pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000654 ! exposure to pentachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34219 ! has exposure stimulus 2,3,4,5,6-pentachlorobiphenyl
relationship: RO:0002309 CHEBI:34219 ! has exposure stimulus 2,3,4,5,6-pentachlorobiphenyl

[Term]
id: ECTO:9000617
name: exposure to 2,3,4,5-tetrachlorobiphenyl
def: "An exposure to 2,3,4,5-tetrachlorobiphenyl." []
synonym: "2,3,4,5-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34221 ! has exposure stimulus 2,3,4,5-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:34221 ! has exposure stimulus 2,3,4,5-tetrachlorobiphenyl

[Term]
id: ECTO:9000618
name: exposure to 2,3,4-trichlorobiphenyl
def: "An exposure to 2,3,4-trichlorobiphenyl." []
synonym: "2,3,4-trichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000652 ! exposure to trichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34222 ! has exposure stimulus 2,3,4-trichlorobiphenyl
relationship: RO:0002309 CHEBI:34222 ! has exposure stimulus 2,3,4-trichlorobiphenyl

[Term]
id: ECTO:9000619
name: exposure to 2,3,5,6-tetrachlorobiphenyl
def: "An exposure to 2,3,5,6-tetrachlorobiphenyl." []
synonym: "2,3,5,6-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34224 ! has exposure stimulus 2,3,5,6-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:34224 ! has exposure stimulus 2,3,5,6-tetrachlorobiphenyl

[Term]
id: ECTO:9000620
name: exposure to 2,3,6-trichlorobiphenyl
def: "An exposure to 2,3,6-trichlorobiphenyl." []
synonym: "2,3,6-trichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000652 ! exposure to trichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34225 ! has exposure stimulus 2,3,6-trichlorobiphenyl
relationship: RO:0002309 CHEBI:34225 ! has exposure stimulus 2,3,6-trichlorobiphenyl

[Term]
id: ECTO:9000621
name: exposure to 2,4'-dichlorobiphenyl
def: "An exposure to 2,4'-dichlorobiphenyl." []
synonym: "2,4'-dichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000651 ! exposure to dichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34232 ! has exposure stimulus 2,4'-dichlorobiphenyl
relationship: RO:0002309 CHEBI:34232 ! has exposure stimulus 2,4'-dichlorobiphenyl

[Term]
id: ECTO:9000622
name: exposure to 2,4,4',6-tetrachlorobiphenyl
def: "An exposure to 2,4,4',6-tetrachlorobiphenyl." []
synonym: "2,4,4',6-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34233 ! has exposure stimulus 2,4,4',6-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:34233 ! has exposure stimulus 2,4,4',6-tetrachlorobiphenyl

[Term]
id: ECTO:9000623
name: exposure to 2,5-dichlorobiphenyl
def: "An exposure to 2,5-dichlorobiphenyl." []
synonym: "2,5-dichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000651 ! exposure to dichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34246 ! has exposure stimulus 2,5-dichlorobiphenyl
relationship: RO:0002309 CHEBI:34246 ! has exposure stimulus 2,5-dichlorobiphenyl

[Term]
id: ECTO:9000624
name: exposure to 2,6-dichlorobiphenyl
def: "An exposure to 2,6-dichlorobiphenyl." []
synonym: "2,6-dichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000651 ! exposure to dichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34249 ! has exposure stimulus 2,6-dichlorobiphenyl
relationship: RO:0002309 CHEBI:34249 ! has exposure stimulus 2,6-dichlorobiphenyl

[Term]
id: ECTO:9000625
name: exposure to 2,6-dimethylnaphthalene
def: "An exposure to 2,6-dimethylnaphthalene." []
synonym: "2,6-dimethylnaphthalene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34251 ! has exposure stimulus 2,6-dimethylnaphthalene
relationship: RO:0002309 CHEBI:34251 ! has exposure stimulus 2,6-dimethylnaphthalene

[Term]
id: ECTO:9000626
name: exposure to oxybenzone
def: "An exposure to oxybenzone." []
synonym: "oxybenzone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34283 ! has exposure stimulus oxybenzone
relationship: RO:0002309 CHEBI:34283 ! has exposure stimulus oxybenzone

[Term]
id: ECTO:9000627
name: exposure to fenobucarb
def: "An exposure to fenobucarb." []
synonym: "fenobucarb exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34304 ! has exposure stimulus fenobucarb
relationship: RO:0002309 CHEBI:34304 ! has exposure stimulus fenobucarb

[Term]
id: ECTO:9000628
name: exposure to 3,5-dichlorobiphenyl
def: "An exposure to 3,5-dichlorobiphenyl." []
synonym: "3,5-dichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000651 ! exposure to dichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34326 ! has exposure stimulus 3,5-dichlorobiphenyl
relationship: RO:0002309 CHEBI:34326 ! has exposure stimulus 3,5-dichlorobiphenyl

[Term]
id: ECTO:9000629
name: exposure to 4,4'-dichlorobiphenyl
def: "An exposure to 4,4'-dichlorobiphenyl." []
synonym: "4,4'-dichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000651 ! exposure to dichlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34364 ! has exposure stimulus 4,4'-dichlorobiphenyl
relationship: RO:0002309 CHEBI:34364 ! has exposure stimulus 4,4'-dichlorobiphenyl

[Term]
id: ECTO:9000630
name: exposure to 4-nonylphenol
def: "An exposure to 4-nonylphenol." []
synonym: "4-nonylphenol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34440 ! has exposure stimulus 4-nonylphenol
relationship: RO:0002309 CHEBI:34440 ! has exposure stimulus 4-nonylphenol

[Term]
id: ECTO:9000631
name: exposure to bromodichloromethane
def: "An exposure to bromodichloromethane." []
synonym: "bromodichloromethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34591 ! has exposure stimulus bromodichloromethane
relationship: RO:0002309 CHEBI:34591 ! has exposure stimulus bromodichloromethane

[Term]
id: ECTO:9000632
name: exposure to chlordane
def: "An exposure to chlordane." []
synonym: "chlordane exposure" EXACT []
is_a: ECTO:9000283 ! exposure to cyclodiene organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34623 ! has exposure stimulus chlordane
relationship: RO:0002309 CHEBI:34623 ! has exposure stimulus chlordane

[Term]
id: ECTO:9000633
name: exposure to chlorpyrifos
def: "An exposure to chlorpyrifos." []
synonym: "chlorpyrifos exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34631 ! has exposure stimulus chlorpyrifos
relationship: RO:0002309 CHEBI:34631 ! has exposure stimulus chlorpyrifos

[Term]
id: ECTO:9000634
name: exposure to chlorpyrifos-methyl
def: "An exposure to chlorpyrifos-methyl." []
synonym: "chlorpyrifos-methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34632 ! has exposure stimulus chlorpyrifos-methyl
relationship: RO:0002309 CHEBI:34632 ! has exposure stimulus chlorpyrifos-methyl

[Term]
id: ECTO:9000635
name: exposure to decachlorobiphenyl
def: "An exposure to decachlorobiphenyl." []
synonym: "decachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000068 ! exposure to polychlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34666 ! has exposure stimulus decachlorobiphenyl
relationship: RO:0002309 CHEBI:34666 ! has exposure stimulus decachlorobiphenyl

[Term]
id: ECTO:9000636
name: exposure to diazinon
def: "An exposure to diazinon." []
synonym: "diazinon exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34682 ! has exposure stimulus diazinon
relationship: RO:0002309 CHEBI:34682 ! has exposure stimulus diazinon

[Term]
id: ECTO:9000637
name: exposure to dibutyl phthalate
def: "An exposure to dibutyl phthalate." []
synonym: "dibutyl phthalate exposure" EXACT []
is_a: ECTO:9000906 ! exposure to phthalate ester
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34687 ! has exposure stimulus dibutyl phthalate
relationship: RO:0002309 CHEBI:34687 ! has exposure stimulus dibutyl phthalate

[Term]
id: ECTO:9000638
name: exposure to dimethoate
def: "An exposure to dimethoate." []
synonym: "dimethoate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34714 ! has exposure stimulus dimethoate
relationship: RO:0002309 CHEBI:34714 ! has exposure stimulus dimethoate

[Term]
id: ECTO:9000639
name: exposure to dinoseb
def: "An exposure to dinoseb." []
synonym: "dinoseb exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34719 ! has exposure stimulus dinoseb
relationship: RO:0002309 CHEBI:34719 ! has exposure stimulus dinoseb

[Term]
id: ECTO:9000640
name: exposure to heptachlor
def: "An exposure to heptachlor." []
synonym: "heptachlor exposure" EXACT []
is_a: ECTO:9000283 ! exposure to cyclodiene organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34785 ! has exposure stimulus heptachlor
relationship: RO:0002309 CHEBI:34785 ! has exposure stimulus heptachlor

[Term]
id: ECTO:9000641
name: exposure to metribuzin
def: "An exposure to metribuzin." []
synonym: "metribuzin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34846 ! has exposure stimulus metribuzin
relationship: RO:0002309 CHEBI:34846 ! has exposure stimulus metribuzin

[Term]
id: ECTO:9000642
name: exposure to mirex
def: "An exposure to mirex." []
synonym: "mirex exposure" EXACT []
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34852 ! has exposure stimulus mirex
relationship: RO:0002309 CHEBI:34852 ! has exposure stimulus mirex

[Term]
id: ECTO:9000643
name: exposure to prometon
def: "An exposure to prometon." []
synonym: "prometon exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34934 ! has exposure stimulus prometon
relationship: RO:0002309 CHEBI:34934 ! has exposure stimulus prometon

[Term]
id: ECTO:9000644
name: exposure to trifluralin
def: "An exposure to trifluralin." []
synonym: "trifluralin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35027 ! has exposure stimulus trifluralin
relationship: RO:0002309 CHEBI:35027 ! has exposure stimulus trifluralin

[Term]
id: ECTO:9000645
name: exposure to tris(2-butoxyethyl) phosphate
def: "An exposure to tris(2-butoxyethyl) phosphate." []
synonym: "tris(2-butoxyethyl) phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35038 ! has exposure stimulus tris(2-butoxyethyl) phosphate
relationship: RO:0002309 CHEBI:35038 ! has exposure stimulus tris(2-butoxyethyl) phosphate

[Term]
id: ECTO:9000646
name: exposure to 3,3',5,5'-tetrachlorobiphenyl
def: "An exposure to 3,3',5,5'-tetrachlorobiphenyl." []
synonym: "3,3',5,5'-tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35445 ! has exposure stimulus 3,3',5,5'-tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:35445 ! has exposure stimulus 3,3',5,5'-tetrachlorobiphenyl

[Term]
id: ECTO:9000647
name: exposure to perfluorodecanoic acid
def: "An exposure to perfluorodecanoic acid." []
synonym: "perfluorodecanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35546 ! has exposure stimulus perfluorodecanoic acid
relationship: RO:0002309 CHEBI:35546 ! has exposure stimulus perfluorodecanoic acid

[Term]
id: ECTO:9000648
name: exposure to perfluoroheptanoic acid
def: "An exposure to perfluoroheptanoic acid." []
synonym: "perfluoroheptanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35547 ! has exposure stimulus perfluoroheptanoic acid
relationship: RO:0002309 CHEBI:35547 ! has exposure stimulus perfluoroheptanoic acid

[Term]
id: ECTO:9000649
name: obsolete perfluorooctanoic acid exposure
is_obsolete: true
replaced_by: ECTO:9000095

[Term]
id: ECTO:9000650
name: exposure to cetirizine
def: "An exposure to cetirizine." []
synonym: "cetirizine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3561 ! has exposure stimulus cetirizine
relationship: RO:0002309 CHEBI:3561 ! has exposure stimulus cetirizine

[Term]
id: ECTO:9000651
name: exposure to dichlorobiphenyl
def: "An exposure to dichlorobiphenyl." []
synonym: "dichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000068 ! exposure to polychlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36718 ! has exposure stimulus dichlorobiphenyl
relationship: RO:0002309 CHEBI:36718 ! has exposure stimulus dichlorobiphenyl

[Term]
id: ECTO:9000652
name: exposure to trichlorobiphenyl
def: "An exposure to trichlorobiphenyl." []
synonym: "trichlorobiphenyl exposure" EXACT []
is_a: ECTO:9000068 ! exposure to polychlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36719 ! has exposure stimulus trichlorobiphenyl
relationship: RO:0002309 CHEBI:36719 ! has exposure stimulus trichlorobiphenyl

[Term]
id: ECTO:9000653
name: exposure to tetrachlorobiphenyl
def: "An exposure to tetrachlorobiphenyl." []
synonym: "tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000068 ! exposure to polychlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36720 ! has exposure stimulus tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:36720 ! has exposure stimulus tetrachlorobiphenyl

[Term]
id: ECTO:9000654
name: exposure to pentachlorobiphenyl
def: "An exposure to pentachlorobiphenyl." []
synonym: "pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000068 ! exposure to polychlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36721 ! has exposure stimulus pentachlorobiphenyl
relationship: RO:0002309 CHEBI:36721 ! has exposure stimulus pentachlorobiphenyl

[Term]
id: ECTO:9000655
name: exposure to hexachlorobiphenyl
def: "An exposure to hexachlorobiphenyl." []
synonym: "hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000068 ! exposure to polychlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36722 ! has exposure stimulus hexachlorobiphenyl
relationship: RO:0002309 CHEBI:36722 ! has exposure stimulus hexachlorobiphenyl

[Term]
id: ECTO:9000656
name: exposure to (S)-bupropion
def: "An exposure to (S)-bupropion." []
synonym: "(S)-bupropion exposure" EXACT []
is_a: ECTO:9000600 ! exposure to bupropion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36793 ! has exposure stimulus (S)-bupropion
relationship: RO:0002309 CHEBI:36793 ! has exposure stimulus (S)-bupropion

[Term]
id: ECTO:9000657
name: exposure to (R)-bupropion
def: "An exposure to (R)-bupropion." []
synonym: "(R)-bupropion exposure" EXACT []
is_a: ECTO:9000600 ! exposure to bupropion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36794 ! has exposure stimulus (R)-bupropion
relationship: RO:0002309 CHEBI:36794 ! has exposure stimulus (R)-bupropion

[Term]
id: ECTO:9000658
name: exposure to (trifluoromethyl)benzene
def: "An exposure to (trifluoromethyl)benzene." []
synonym: "(trifluoromethyl)benzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36810 ! has exposure stimulus (trifluoromethyl)benzene
relationship: RO:0002309 CHEBI:36810 ! has exposure stimulus (trifluoromethyl)benzene

[Term]
id: ECTO:9000659
name: exposure to cilastatin
def: "An exposure to cilastatin." []
synonym: "cilastatin exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3697 ! has exposure stimulus cilastatin
relationship: RO:0002309 CHEBI:3697 ! has exposure stimulus cilastatin

[Term]
id: ECTO:9000660
name: exposure to citalopram
def: "An exposure to citalopram." []
synonym: "citalopram exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3723 ! has exposure stimulus citalopram
relationship: RO:0002309 CHEBI:3723 ! has exposure stimulus citalopram

[Term]
id: ECTO:9000661
name: exposure to clarithromycin
def: "An exposure to clarithromycin." []
synonym: "clarithromycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3732 ! has exposure stimulus clarithromycin
relationship: RO:0002309 CHEBI:3732 ! has exposure stimulus clarithromycin

[Term]
id: ECTO:9000662
name: exposure to clindamycin
def: "An exposure to clindamycin." []
synonym: "clindamycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3745 ! has exposure stimulus clindamycin
relationship: RO:0002309 CHEBI:3745 ! has exposure stimulus clindamycin

[Term]
id: ECTO:9000663
name: exposure to clomazone
def: "An exposure to clomazone." []
synonym: "clomazone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3751 ! has exposure stimulus clomazone
relationship: RO:0002309 CHEBI:3751 ! has exposure stimulus clomazone

[Term]
id: ECTO:9000664
name: exposure to clotrimazole
def: "An exposure to clotrimazole." []
synonym: "clotrimazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3764 ! has exposure stimulus clotrimazole
relationship: RO:0002309 CHEBI:3764 ! has exposure stimulus clotrimazole

[Term]
id: ECTO:9000665
name: exposure to propazine
def: "An exposure to propazine." []
synonym: "propazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38067 ! has exposure stimulus propazine
relationship: RO:0002309 CHEBI:38067 ! has exposure stimulus propazine

[Term]
id: ECTO:9000666
name: exposure to cyanazine
def: "An exposure to cyanazine." []
synonym: "cyanazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002139 ! exposure to nitrile
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38069 ! has exposure stimulus cyanazine
relationship: RO:0002309 CHEBI:38069 ! has exposure stimulus cyanazine

[Term]
id: ECTO:9000667
name: exposure to monuron
def: "An exposure to monuron." []
synonym: "monuron exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38214 ! has exposure stimulus monuron
relationship: RO:0002309 CHEBI:38214 ! has exposure stimulus monuron

[Term]
id: ECTO:9000668
name: exposure to mesotrione
def: "An exposure to mesotrione." []
synonym: "mesotrione exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38321 ! has exposure stimulus mesotrione
relationship: RO:0002309 CHEBI:38321 ! has exposure stimulus mesotrione

[Term]
id: ECTO:9000669
name: exposure to perfluorononanoic acid
def: "An exposure to perfluorononanoic acid." []
synonym: "perfluorononanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38397 ! has exposure stimulus perfluorononanoic acid
relationship: RO:0002309 CHEBI:38397 ! has exposure stimulus perfluorononanoic acid

[Term]
id: ECTO:9000670
name: exposure to methoxyfenozide
def: "An exposure to methoxyfenozide." []
synonym: "methoxyfenozide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38449 ! has exposure stimulus methoxyfenozide
relationship: RO:0002309 CHEBI:38449 ! has exposure stimulus methoxyfenozide

[Term]
id: ECTO:9000671
name: exposure to tebufenozide
def: "An exposure to tebufenozide." []
synonym: "tebufenozide exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38452 ! has exposure stimulus tebufenozide
relationship: RO:0002309 CHEBI:38452 ! has exposure stimulus tebufenozide

[Term]
id: ECTO:9000672
name: exposure to methiocarb
def: "An exposure to methiocarb." []
synonym: "methiocarb exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38508 ! has exposure stimulus methiocarb
relationship: RO:0002309 CHEBI:38508 ! has exposure stimulus methiocarb

[Term]
id: ECTO:9000673
name: exposure to rosuvastatin
def: "An exposure to rosuvastatin." []
synonym: "rosuvastatin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000259 ! exposure to statin
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38545 ! has exposure stimulus rosuvastatin
relationship: RO:0002309 CHEBI:38545 ! has exposure stimulus rosuvastatin

[Term]
id: ECTO:9000674
name: exposure to ethion
def: "An exposure to ethion." []
synonym: "ethion exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38663 ! has exposure stimulus ethion
relationship: RO:0002309 CHEBI:38663 ! has exposure stimulus ethion

[Term]
id: ECTO:9000675
name: exposure to parathion-methyl
def: "An exposure to parathion-methyl." []
synonym: "parathion-methyl exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38746 ! has exposure stimulus parathion-methyl
relationship: RO:0002309 CHEBI:38746 ! has exposure stimulus parathion-methyl

[Term]
id: ECTO:9000676
name: exposure to pirimiphos-methyl
def: "An exposure to pirimiphos-methyl." []
synonym: "pirimiphos-methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38843 ! has exposure stimulus pirimiphos-methyl
relationship: RO:0002309 CHEBI:38843 ! has exposure stimulus pirimiphos-methyl

[Term]
id: ECTO:9000677
name: exposure to cis-chlordane
def: "An exposure to cis-chlordane." []
synonym: "cis-chlordane exposure" EXACT []
is_a: ECTO:9000632 ! exposure to chlordane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39068 ! has exposure stimulus cis-chlordane
relationship: RO:0002309 CHEBI:39068 ! has exposure stimulus cis-chlordane

[Term]
id: ECTO:9000678
name: exposure to trans-chlordane
def: "An exposure to trans-chlordane." []
synonym: "trans-chlordane exposure" EXACT []
is_a: ECTO:9000632 ! exposure to chlordane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39069 ! has exposure stimulus trans-chlordane
relationship: RO:0002309 CHEBI:39069 ! has exposure stimulus trans-chlordane

[Term]
id: ECTO:9000679
name: exposure to alpha-hexachlorocyclohexane
def: "An exposure to alpha-hexachlorocyclohexane." []
synonym: "alpha-hexachlorocyclohexane exposure" EXACT []
is_a: ECTO:9002415 ! exposure to hexachlorocyclohexane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39096 ! has exposure stimulus alpha-hexachlorocyclohexane
relationship: RO:0002309 CHEBI:39096 ! has exposure stimulus alpha-hexachlorocyclohexane

[Term]
id: ECTO:9000680
name: exposure to acetamiprid
def: "An exposure to acetamiprid." []
synonym: "acetamiprid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39163 ! has exposure stimulus acetamiprid
relationship: RO:0002309 CHEBI:39163 ! has exposure stimulus acetamiprid

[Term]
id: ECTO:9000681
name: exposure to (E)-acetamiprid
def: "An exposure to (E)-acetamiprid." []
synonym: "(E)-acetamiprid exposure" EXACT []
is_a: ECTO:9000680 ! exposure to acetamiprid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39164 ! has exposure stimulus (E)-acetamiprid
relationship: RO:0002309 CHEBI:39164 ! has exposure stimulus (E)-acetamiprid

[Term]
id: ECTO:9000682
name: exposure to (Z)-acetamiprid
def: "An exposure to (Z)-acetamiprid." []
synonym: "(Z)-acetamiprid exposure" EXACT []
is_a: ECTO:9000680 ! exposure to acetamiprid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39165 ! has exposure stimulus (Z)-acetamiprid
relationship: RO:0002309 CHEBI:39165 ! has exposure stimulus (Z)-acetamiprid

[Term]
id: ECTO:9000683
name: exposure to (E)-imidacloprid
def: "An exposure to (E)-imidacloprid." []
synonym: "(E)-imidacloprid exposure" EXACT []
is_a: ECTO:9000415 ! exposure to imidacloprid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39168 ! has exposure stimulus (E)-imidacloprid
relationship: RO:0002309 CHEBI:39168 ! has exposure stimulus (E)-imidacloprid

[Term]
id: ECTO:9000684
name: exposure to (Z)-imidacloprid
def: "An exposure to (Z)-imidacloprid." []
synonym: "(Z)-imidacloprid exposure" EXACT []
is_a: ECTO:9000415 ! exposure to imidacloprid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39169 ! has exposure stimulus (Z)-imidacloprid
relationship: RO:0002309 CHEBI:39169 ! has exposure stimulus (Z)-imidacloprid

[Term]
id: ECTO:9000685
name: exposure to thiacloprid
def: "An exposure to thiacloprid." []
synonym: "thiacloprid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39175 ! has exposure stimulus thiacloprid
relationship: RO:0002309 CHEBI:39175 ! has exposure stimulus thiacloprid

[Term]
id: ECTO:9000686
name: exposure to (Z)-thiacloprid
def: "An exposure to (Z)-thiacloprid." []
synonym: "(Z)-thiacloprid exposure" EXACT []
is_a: ECTO:9000685 ! exposure to thiacloprid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39176 ! has exposure stimulus (Z)-thiacloprid
relationship: RO:0002309 CHEBI:39176 ! has exposure stimulus (Z)-thiacloprid

[Term]
id: ECTO:9000687
name: exposure to (E)-clothianidin
def: "An exposure to (E)-clothianidin." []
synonym: "(E)-clothianidin exposure" EXACT []
is_a: ECTO:9000688 ! exposure to clothianidin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39177 ! has exposure stimulus (E)-clothianidin
relationship: RO:0002309 CHEBI:39177 ! has exposure stimulus (E)-clothianidin

[Term]
id: ECTO:9000688
name: exposure to clothianidin
def: "An exposure to clothianidin." []
synonym: "clothianidin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39178 ! has exposure stimulus clothianidin
relationship: RO:0002309 CHEBI:39178 ! has exposure stimulus clothianidin

[Term]
id: ECTO:9000689
name: exposure to thiamethoxam
def: "An exposure to thiamethoxam." []
synonym: "thiamethoxam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39185 ! has exposure stimulus thiamethoxam
relationship: RO:0002309 CHEBI:39185 ! has exposure stimulus thiamethoxam

[Term]
id: ECTO:9000690
name: exposure to (E)-thiamethoxam
def: "An exposure to (E)-thiamethoxam." []
synonym: "(E)-thiamethoxam exposure" EXACT []
is_a: ECTO:9000689 ! exposure to thiamethoxam
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39186 ! has exposure stimulus (E)-thiamethoxam
relationship: RO:0002309 CHEBI:39186 ! has exposure stimulus (E)-thiamethoxam

[Term]
id: ECTO:9000691
name: exposure to flonicamid
def: "An exposure to flonicamid." []
synonym: "flonicamid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39291 ! has exposure stimulus flonicamid
relationship: RO:0002309 CHEBI:39291 ! has exposure stimulus flonicamid

[Term]
id: ECTO:9000692
name: exposure to pymetrozine
def: "An exposure to pymetrozine." []
synonym: "pymetrozine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39311 ! has exposure stimulus pymetrozine
relationship: RO:0002309 CHEBI:39311 ! has exposure stimulus pymetrozine

[Term]
id: ECTO:9000693
name: exposure to teflubenzuron
def: "An exposure to teflubenzuron." []
synonym: "teflubenzuron exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39387 ! has exposure stimulus teflubenzuron
relationship: RO:0002309 CHEBI:39387 ! has exposure stimulus teflubenzuron

[Term]
id: ECTO:9000695
name: exposure to perfluorobutyric acid
def: "An exposure to perfluorobutyric acid." []
synonym: "perfluorobutyric acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39426 ! has exposure stimulus perfluorobutyric acid
relationship: RO:0002309 CHEBI:39426 ! has exposure stimulus perfluorobutyric acid

[Term]
id: ECTO:9000696
name: exposure to atorvastatin
def: "An exposure to atorvastatin." []
synonym: "atorvastatin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000259 ! exposure to statin
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39548 ! has exposure stimulus atorvastatin
relationship: RO:0002309 CHEBI:39548 ! has exposure stimulus atorvastatin

[Term]
id: ECTO:9000697
name: exposure to metsulfuron methyl
def: "An exposure to metsulfuron methyl." []
synonym: "metsulfuron methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39678 ! has exposure stimulus metsulfuron methyl
relationship: RO:0002309 CHEBI:39678 ! has exposure stimulus metsulfuron methyl

[Term]
id: ECTO:9000698
name: exposure to sitagliptin
def: "An exposure to sitagliptin." []
synonym: "sitagliptin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:40237 ! has exposure stimulus sitagliptin
relationship: RO:0002309 CHEBI:40237 ! has exposure stimulus sitagliptin

[Term]
id: ECTO:9000699
name: exposure to cyprodinil
def: "An exposure to cyprodinil." []
synonym: "cyprodinil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4045 ! has exposure stimulus cyprodinil
relationship: RO:0002309 CHEBI:4045 ! has exposure stimulus cyprodinil

[Term]
id: ECTO:9000700
name: exposure to azoxystrobin
def: "An exposure to azoxystrobin." []
synonym: "azoxystrobin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:40909 ! has exposure stimulus azoxystrobin
relationship: RO:0002309 CHEBI:40909 ! has exposure stimulus azoxystrobin

[Term]
id: ECTO:9000701
name: exposure to decylamine-N,N-dimethyl-N-oxide
def: "An exposure to decylamine-N,N-dimethyl-N-oxide." []
synonym: "decylamine-N,N-dimethyl-N-oxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41899 ! has exposure stimulus decylamine-N,N-dimethyl-N-oxide
relationship: RO:0002309 CHEBI:41899 ! has exposure stimulus decylamine-N,N-dimethyl-N-oxide

[Term]
id: ECTO:9000702
name: exposure to erythromycin A
def: "An exposure to erythromycin A." []
synonym: "erythromycin A exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000361 ! exposure to erythromycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42355 ! has exposure stimulus erythromycin A
relationship: RO:0002309 CHEBI:42355 ! has exposure stimulus erythromycin A

[Term]
id: ECTO:9000703
name: exposure to (R)-amphetamine
def: "An exposure to (R)-amphetamine." []
synonym: "(R)-amphetamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42724 ! has exposure stimulus (R)-amphetamine
relationship: RO:0002309 CHEBI:42724 ! has exposure stimulus (R)-amphetamine

[Term]
id: ECTO:9000704
name: exposure to gabapentin
def: "An exposure to gabapentin." []
synonym: "gabapentin exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42797 ! has exposure stimulus gabapentin
relationship: RO:0002309 CHEBI:42797 ! has exposure stimulus gabapentin

[Term]
id: ECTO:9000705
name: exposure to dexibuprofen
def: "An exposure to dexibuprofen." []
synonym: "dexibuprofen exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000743 ! exposure to ibuprofen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43415 ! has exposure stimulus dexibuprofen
relationship: RO:0002309 CHEBI:43415 ! has exposure stimulus dexibuprofen

[Term]
id: ECTO:9000706
name: exposure to terbutryn
def: "An exposure to terbutryn." []
synonym: "terbutryn exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002558 ! exposure to polyamine
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44156 ! has exposure stimulus terbutryn
relationship: RO:0002309 CHEBI:44156 ! has exposure stimulus terbutryn

[Term]
id: ECTO:9000707
name: exposure to naphthalene-2-sulfonic acid
def: "An exposure to naphthalene-2-sulfonic acid." []
synonym: "naphthalene-2-sulfonic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44229 ! has exposure stimulus naphthalene-2-sulfonic acid
relationship: RO:0002309 CHEBI:44229 ! has exposure stimulus naphthalene-2-sulfonic acid

[Term]
id: ECTO:9000708
name: exposure to (S)-amphetamine
def: "An exposure to (S)-amphetamine." []
synonym: "(S)-amphetamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4469 ! has exposure stimulus (S)-amphetamine
relationship: RO:0002309 CHEBI:4469 ! has exposure stimulus (S)-amphetamine

[Term]
id: ECTO:9000709
name: exposure to ritonavir
def: "An exposure to ritonavir." []
synonym: "ritonavir exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45409 ! has exposure stimulus ritonavir
relationship: RO:0002309 CHEBI:45409 ! has exposure stimulus ritonavir

[Term]
id: ECTO:9000710
name: exposure to trimethoprim
def: "An exposure to trimethoprim." []
synonym: "trimethoprim exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45924 ! has exposure stimulus trimethoprim
relationship: RO:0002309 CHEBI:45924 ! has exposure stimulus trimethoprim

[Term]
id: ECTO:9000711
name: exposure to benzothiazole
def: "An exposure to benzothiazole." []
synonym: "benzothiazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45993 ! has exposure stimulus benzothiazole
relationship: RO:0002309 CHEBI:45993 ! has exposure stimulus benzothiazole

[Term]
id: ECTO:9000712
name: exposure to fluconazole
def: "An exposure to fluconazole." []
synonym: "fluconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46081 ! has exposure stimulus fluconazole
relationship: RO:0002309 CHEBI:46081 ! has exposure stimulus fluconazole

[Term]
id: ECTO:9000713
name: exposure to diglyme
def: "An exposure to diglyme." []
synonym: "diglyme exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46784 ! has exposure stimulus diglyme
relationship: RO:0002309 CHEBI:46784 ! has exposure stimulus diglyme

[Term]
id: ECTO:9000714
name: exposure to pentachlorobenzene
def: "An exposure to pentachlorobenzene." []
synonym: "pentachlorobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47136 ! has exposure stimulus pentachlorobenzene
relationship: RO:0002309 CHEBI:47136 ! has exposure stimulus pentachlorobenzene

[Term]
id: ECTO:9000715
name: exposure to diclofenac
def: "An exposure to diclofenac." []
synonym: "diclofenac exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47381 ! has exposure stimulus diclofenac
relationship: RO:0002309 CHEBI:47381 ! has exposure stimulus diclofenac

[Term]
id: ECTO:9000716
name: exposure to furosemide
def: "An exposure to furosemide." []
synonym: "furosemide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47426 ! has exposure stimulus furosemide
relationship: RO:0002309 CHEBI:47426 ! has exposure stimulus furosemide

[Term]
id: ECTO:9000717
name: exposure to bezafibrate
def: "An exposure to bezafibrate." []
synonym: "bezafibrate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47612 ! has exposure stimulus bezafibrate
relationship: RO:0002309 CHEBI:47612 ! has exposure stimulus bezafibrate

[Term]
id: ECTO:9000718
name: exposure to 2,4,6-tribromophenol
def: "An exposure to 2,4,6-tribromophenol." []
synonym: "2,4,6-tribromophenol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47696 ! has exposure stimulus 2,4,6-tribromophenol
relationship: RO:0002309 CHEBI:47696 ! has exposure stimulus 2,4,6-tribromophenol

[Term]
id: ECTO:9000719
name: exposure to levibuprofen
def: "An exposure to levibuprofen." []
synonym: "levibuprofen exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000743 ! exposure to ibuprofen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47835 ! has exposure stimulus levibuprofen
relationship: RO:0002309 CHEBI:47835 ! has exposure stimulus levibuprofen

[Term]
id: ECTO:9000720
name: exposure to endosulfan
def: "An exposure to endosulfan." []
synonym: "endosulfan exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000283 ! exposure to cyclodiene organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4791 ! has exposure stimulus endosulfan
relationship: RO:0002309 CHEBI:4791 ! has exposure stimulus endosulfan

[Term]
id: ECTO:9000721
name: exposure to epoxiconazole
def: "An exposure to epoxiconazole." []
synonym: "epoxiconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4811 ! has exposure stimulus epoxiconazole
relationship: RO:0002309 CHEBI:4811 ! has exposure stimulus epoxiconazole

[Term]
id: ECTO:9000722
name: exposure to eprosartan
def: "An exposure to eprosartan." []
synonym: "eprosartan exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4814 ! has exposure stimulus eprosartan
relationship: RO:0002309 CHEBI:4814 ! has exposure stimulus eprosartan

[Term]
id: ECTO:9000723
name: exposure to trichlorofluoromethane
def: "An exposure to trichlorofluoromethane." []
synonym: "trichlorofluoromethane exposure" EXACT []
is_a: ECTO:9001542 ! exposure to chlorofluorocarbon
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48236 ! has exposure stimulus trichlorofluoromethane
relationship: RO:0002309 CHEBI:48236 ! has exposure stimulus trichlorofluoromethane

[Term]
id: ECTO:9000724
name: exposure to triclocarban
def: "An exposure to triclocarban." []
synonym: "triclocarban exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48347 ! has exposure stimulus triclocarban
relationship: RO:0002309 CHEBI:48347 ! has exposure stimulus triclocarban

[Term]
id: ECTO:9000725
name: exposure to ethambutol
def: "An exposure to ethambutol." []
synonym: "ethambutol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4877 ! has exposure stimulus ethambutol
relationship: RO:0002309 CHEBI:4877 ! has exposure stimulus ethambutol

[Term]
id: ECTO:9000726
name: exposure to (E)-roxithromycin
def: "An exposure to (E)-roxithromycin." []
synonym: "(E)-roxithromycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48935 ! has exposure stimulus (E)-roxithromycin
relationship: RO:0002309 CHEBI:48935 ! has exposure stimulus (E)-roxithromycin

[Term]
id: ECTO:9000727
name: exposure to exemestane
def: "An exposure to exemestane." []
synonym: "exemestane exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4953 ! has exposure stimulus exemestane
relationship: RO:0002309 CHEBI:4953 ! has exposure stimulus exemestane

[Term]
id: ECTO:9000728
name: exposure to diazepam
def: "An exposure to diazepam." []
synonym: "diazepam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49575 ! has exposure stimulus diazepam
relationship: RO:0002309 CHEBI:49575 ! has exposure stimulus diazepam

[Term]
id: ECTO:9000729
name: exposure to indometacin
def: "An exposure to indometacin." []
synonym: "indometacin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49662 ! has exposure stimulus indometacin
relationship: RO:0002309 CHEBI:49662 ! has exposure stimulus indometacin

[Term]
id: ECTO:9000730
name: exposure to fenoxycarb
def: "An exposure to fenoxycarb." []
synonym: "fenoxycarb exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5009 ! has exposure stimulus fenoxycarb
relationship: RO:0002309 CHEBI:5009 ! has exposure stimulus fenoxycarb

[Term]
id: ECTO:9000731
name: exposure to (4-chloro-2-methylphenoxy)acetic acid
def: "An exposure to (4-chloro-2-methylphenoxy)acetic acid." []
synonym: "(4-chloro-2-methylphenoxy)acetic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50099 ! has exposure stimulus (4-chloro-2-methylphenoxy)acetic acid
relationship: RO:0002309 CHEBI:50099 ! has exposure stimulus (4-chloro-2-methylphenoxy)acetic acid

[Term]
id: ECTO:9000732
name: exposure to fenpropimorph
def: "An exposure to fenpropimorph." []
synonym: "fenpropimorph exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50145 ! has exposure stimulus fenpropimorph
relationship: RO:0002309 CHEBI:50145 ! has exposure stimulus fenpropimorph

[Term]
id: ECTO:9000733
name: exposure to fipronil
def: "An exposure to fipronil." []
synonym: "fipronil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5063 ! has exposure stimulus fipronil
relationship: RO:0002309 CHEBI:5063 ! has exposure stimulus fipronil

[Term]
id: ECTO:9000734
name: exposure to dronedarone
def: "An exposure to dronedarone." []
synonym: "dronedarone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50659 ! has exposure stimulus dronedarone
relationship: RO:0002309 CHEBI:50659 ! has exposure stimulus dronedarone

[Term]
id: ECTO:9000735
name: exposure to acamprosate
def: "An exposure to acamprosate." []
synonym: "acamprosate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51041 ! has exposure stimulus acamprosate
relationship: RO:0002309 CHEBI:51041 ! has exposure stimulus acamprosate

[Term]
id: ECTO:9000736
name: exposure to (RS)-amphetamine
is_obsolete: true
replaced_by: ECTO:9000154

[Term]
id: ECTO:9000737
name: exposure to chloromethylisothiazolinone
def: "An exposure to chloromethylisothiazolinone." []
synonym: "chloromethylisothiazolinone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53621 ! has exposure stimulus chloromethylisothiazolinone
relationship: RO:0002309 CHEBI:53621 ! has exposure stimulus chloromethylisothiazolinone

[Term]
id: ECTO:9000738
name: exposure to amidotrizoic acid
def: "An exposure to amidotrizoic acid." []
synonym: "amidotrizoic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53691 ! has exposure stimulus amidotrizoic acid
relationship: RO:0002309 CHEBI:53691 ! has exposure stimulus amidotrizoic acid

[Term]
id: ECTO:9000739
name: exposure to (R)-atenolol
def: "An exposure to (R)-atenolol." []
synonym: "(R)-atenolol exposure" EXACT []
is_a: ECTO:9000581 ! exposure to atenolol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:55352 ! has exposure stimulus (R)-atenolol
relationship: RO:0002309 CHEBI:55352 ! has exposure stimulus (R)-atenolol

[Term]
id: ECTO:9000740
name: exposure to hexachlorobenzene
def: "An exposure to hexachlorobenzene." []
synonym: "hexachlorobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5692 ! has exposure stimulus hexachlorobenzene
relationship: RO:0002309 CHEBI:5692 ! has exposure stimulus hexachlorobenzene

[Term]
id: ECTO:9000741
name: exposure to hydrochlorothiazide
def: "An exposure to hydrochlorothiazide." []
synonym: "hydrochlorothiazide exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
is_a: ECTO:9002635 ! exposure to thiazide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5778 ! has exposure stimulus hydrochlorothiazide
relationship: RO:0002309 CHEBI:5778 ! has exposure stimulus hydrochlorothiazide

[Term]
id: ECTO:9000742
name: exposure to (R)-ketamine
def: "An exposure to (R)-ketamine." []
synonym: "(R)-ketamine exposure" EXACT []
is_a: ECTO:9000407 ! exposure to ketamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:580604 ! has exposure stimulus (R)-ketamine
relationship: RO:0002309 CHEBI:580604 ! has exposure stimulus (R)-ketamine

[Term]
id: ECTO:9000743
name: exposure to ibuprofen
def: "An exposure to ibuprofen." []
synonym: "ibuprofen exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5855 ! has exposure stimulus ibuprofen
relationship: RO:0002309 CHEBI:5855 ! has exposure stimulus ibuprofen

[Term]
id: ECTO:9000744
name: exposure to ifosfamide
def: "An exposure to ifosfamide." []
synonym: "ifosfamide exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5864 ! has exposure stimulus ifosfamide
relationship: RO:0002309 CHEBI:5864 ! has exposure stimulus ifosfamide

[Term]
id: ECTO:9000745
name: exposure to mephedrone
def: "An exposure to mephedrone." []
synonym: "mephedrone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59331 ! has exposure stimulus mephedrone
relationship: RO:0002309 CHEBI:59331 ! has exposure stimulus mephedrone

[Term]
id: ECTO:9000746
name: exposure to irbesartan
def: "An exposure to irbesartan." []
synonym: "irbesartan exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5959 ! has exposure stimulus irbesartan
relationship: RO:0002309 CHEBI:5959 ! has exposure stimulus irbesartan

[Term]
id: ECTO:9000747
name: exposure to irgarol 1051
def: "An exposure to irgarol 1051." []
synonym: "irgarol 1051 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002558 ! exposure to polyamine
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5962 ! has exposure stimulus irgarol 1051
relationship: RO:0002309 CHEBI:5962 ! has exposure stimulus irgarol 1051

[Term]
id: ECTO:9000748
name: exposure to isoprothiolane
def: "An exposure to isoprothiolane." []
synonym: "isoprothiolane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6047 ! has exposure stimulus isoprothiolane
relationship: RO:0002309 CHEBI:6047 ! has exposure stimulus isoprothiolane

[Term]
id: ECTO:9000749
name: exposure to isoproturon
def: "An exposure to isoproturon." []
synonym: "isoproturon exposure" EXACT []
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6049 ! has exposure stimulus isoproturon
relationship: RO:0002309 CHEBI:6049 ! has exposure stimulus isoproturon

[Term]
id: ECTO:9000750
name: exposure to esketamine
def: "An exposure to esketamine." []
synonym: "esketamine exposure" EXACT []
is_a: ECTO:9000407 ! exposure to ketamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60799 ! has exposure stimulus esketamine
relationship: RO:0002309 CHEBI:60799 ! has exposure stimulus esketamine

[Term]
id: ECTO:9000751
name: exposure to ketoprofen
def: "An exposure to ketoprofen." []
synonym: "ketoprofen exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6128 ! has exposure stimulus ketoprofen
relationship: RO:0002309 CHEBI:6128 ! has exposure stimulus ketoprofen

[Term]
id: ECTO:9000752
name: exposure to iopromide
def: "An exposure to iopromide." []
synonym: "iopromide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63578 ! has exposure stimulus iopromide
relationship: RO:0002309 CHEBI:63578 ! has exposure stimulus iopromide

[Term]
id: ECTO:9000753
name: exposure to pravastatin
def: "An exposure to pravastatin." []
synonym: "pravastatin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000259 ! exposure to statin
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63618 ! has exposure stimulus pravastatin
relationship: RO:0002309 CHEBI:63618 ! has exposure stimulus pravastatin

[Term]
id: ECTO:9000754
name: exposure to sotalol
def: "An exposure to sotalol." []
synonym: "sotalol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63622 ! has exposure stimulus sotalol
relationship: RO:0002309 CHEBI:63622 ! has exposure stimulus sotalol

[Term]
id: ECTO:9000755
name: exposure to lamotrigine
def: "An exposure to lamotrigine." []
synonym: "lamotrigine exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6367 ! has exposure stimulus lamotrigine
relationship: RO:0002309 CHEBI:6367 ! has exposure stimulus lamotrigine

[Term]
id: ECTO:9000756
name: exposure to amisulpride
def: "An exposure to amisulpride." []
synonym: "amisulpride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64045 ! has exposure stimulus amisulpride
relationship: RO:0002309 CHEBI:64045 ! has exposure stimulus amisulpride

[Term]
id: ECTO:9000757
name: exposure to lenacil
def: "An exposure to lenacil." []
synonym: "lenacil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6407 ! has exposure stimulus lenacil
relationship: RO:0002309 CHEBI:6407 ! has exposure stimulus lenacil

[Term]
id: ECTO:9000758
name: exposure to erythromycin C
def: "An exposure to erythromycin C." []
synonym: "erythromycin C exposure" EXACT []
is_a: ECTO:9000361 ! exposure to erythromycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64273 ! has exposure stimulus erythromycin C
relationship: RO:0002309 CHEBI:64273 ! has exposure stimulus erythromycin C

[Term]
id: ECTO:9000759
name: exposure to levamisole
def: "An exposure to levamisole." []
synonym: "levamisole exposure" EXACT []
is_a: ECTO:9000787 ! exposure to 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6432 ! has exposure stimulus levamisole
relationship: RO:0002309 CHEBI:6432 ! has exposure stimulus levamisole

[Term]
id: ECTO:9000760
name: exposure to levetiracetam
def: "An exposure to levetiracetam." []
synonym: "levetiracetam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6437 ! has exposure stimulus levetiracetam
relationship: RO:0002309 CHEBI:6437 ! has exposure stimulus levetiracetam

[Term]
id: ECTO:9000761
name: exposure to lidocaine
def: "An exposure to lidocaine." []
synonym: "lidocaine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6456 ! has exposure stimulus lidocaine
relationship: RO:0002309 CHEBI:6456 ! has exposure stimulus lidocaine

[Term]
id: ECTO:9000762
name: exposure to linuron
def: "An exposure to linuron." []
synonym: "linuron exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6482 ! has exposure stimulus linuron
relationship: RO:0002309 CHEBI:6482 ! has exposure stimulus linuron

[Term]
id: ECTO:9000763
name: exposure to mefenamic acid
def: "An exposure to mefenamic acid." []
synonym: "mefenamic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6717 ! has exposure stimulus mefenamic acid
relationship: RO:0002309 CHEBI:6717 ! has exposure stimulus mefenamic acid

[Term]
id: ECTO:9000764
name: exposure to metalaxyl
def: "An exposure to metalaxyl." []
synonym: "metalaxyl exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6790 ! has exposure stimulus metalaxyl
relationship: RO:0002309 CHEBI:6790 ! has exposure stimulus metalaxyl

[Term]
id: ECTO:9000765
name: exposure to metamitron
def: "An exposure to metamitron." []
synonym: "metamitron exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6791 ! has exposure stimulus metamitron
relationship: RO:0002309 CHEBI:6791 ! has exposure stimulus metamitron

[Term]
id: ECTO:9000766
name: exposure to metazachlor
def: "An exposure to metazachlor." []
synonym: "metazachlor exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6798 ! has exposure stimulus metazachlor
relationship: RO:0002309 CHEBI:6798 ! has exposure stimulus metazachlor

[Term]
id: ECTO:9000767
name: exposure to metformin hydrochloride
def: "An exposure to metformin hydrochloride." []
synonym: "metformin hydrochloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6802 ! has exposure stimulus metformin hydrochloride
relationship: RO:0002309 CHEBI:6802 ! has exposure stimulus metformin hydrochloride

[Term]
id: ECTO:9000768
name: exposure to methadone
def: "An exposure to methadone." []
synonym: "methadone exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6807 ! has exposure stimulus methadone
relationship: RO:0002309 CHEBI:6807 ! has exposure stimulus methadone

[Term]
id: ECTO:9000769
name: exposure to methamphetamine
def: "An exposure to methamphetamine." []
synonym: "methamphetamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6809 ! has exposure stimulus methamphetamine
relationship: RO:0002309 CHEBI:6809 ! has exposure stimulus methamphetamine

[Term]
id: ECTO:9000770
name: exposure to methomyl
def: "An exposure to methomyl." []
synonym: "methomyl exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6835 ! has exposure stimulus methomyl
relationship: RO:0002309 CHEBI:6835 ! has exposure stimulus methomyl

[Term]
id: ECTO:9000771
name: exposure to 6alpha-methylprednisolone
def: "An exposure to 6alpha-methylprednisolone." []
synonym: "6alpha-methylprednisolone exposure" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
is_a: ECTO:0000258 ! exposure to steroid hormone
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6888 ! has exposure stimulus 6alpha-methylprednisolone
relationship: RO:0002309 CHEBI:6888 ! has exposure stimulus 6alpha-methylprednisolone

[Term]
id: ECTO:9000772
name: exposure to metolachlor
def: "An exposure to metolachlor." []
synonym: "metolachlor exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6902 ! has exposure stimulus metolachlor
relationship: RO:0002309 CHEBI:6902 ! has exposure stimulus metolachlor

[Term]
id: ECTO:9000773
name: exposure to metoprolol
def: "An exposure to metoprolol." []
synonym: "metoprolol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6904 ! has exposure stimulus metoprolol
relationship: RO:0002309 CHEBI:6904 ! has exposure stimulus metoprolol

[Term]
id: ECTO:9000774
name: exposure to metronidazole
def: "An exposure to metronidazole." []
synonym: "metronidazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6909 ! has exposure stimulus metronidazole
relationship: RO:0002309 CHEBI:6909 ! has exposure stimulus metronidazole

[Term]
id: ECTO:9000775
name: exposure to microcystin-LR
def: "An exposure to microcystin-LR." []
synonym: "microcystin-LR exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6925 ! has exposure stimulus microcystin-LR
relationship: RO:0002309 CHEBI:6925 ! has exposure stimulus microcystin-LR

[Term]
id: ECTO:9000776
name: obsolete N,N-diethyl-m-toluamide exposure
is_obsolete: true
replaced_by: ECTO:9000121

[Term]
id: ECTO:9000777
name: exposure to malachite green
def: "An exposure to malachite green." []
synonym: "malachite green exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72449 ! has exposure stimulus malachite green
relationship: RO:0002309 CHEBI:72449 ! has exposure stimulus malachite green

[Term]
id: ECTO:9000778
name: exposure to naltrexone
def: "An exposure to naltrexone." []
synonym: "naltrexone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7465 ! has exposure stimulus naltrexone
relationship: RO:0002309 CHEBI:7465 ! has exposure stimulus naltrexone

[Term]
id: ECTO:9000779
name: exposure to naproxen
def: "An exposure to naproxen." []
synonym: "naproxen exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7476 ! has exposure stimulus naproxen
relationship: RO:0002309 CHEBI:7476 ! has exposure stimulus naproxen

[Term]
id: ECTO:9000780
name: exposure to myclobutanil
def: "An exposure to myclobutanil." []
synonym: "myclobutanil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75281 ! has exposure stimulus myclobutanil
relationship: RO:0002309 CHEBI:75281 ! has exposure stimulus myclobutanil

[Term]
id: ECTO:9000781
name: exposure to benzotriazole
def: "An exposure to benzotriazole." []
synonym: "benzotriazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75331 ! has exposure stimulus benzotriazole
relationship: RO:0002309 CHEBI:75331 ! has exposure stimulus benzotriazole

[Term]
id: ECTO:9000782
name: exposure to dichlorprop
def: "An exposure to dichlorprop." []
synonym: "dichlorprop exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75375 ! has exposure stimulus dichlorprop
relationship: RO:0002309 CHEBI:75375 ! has exposure stimulus dichlorprop

[Term]
id: ECTO:9000783
name: exposure to nicosulfuron
def: "An exposure to nicosulfuron." []
synonym: "nicosulfuron exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7554 ! has exposure stimulus nicosulfuron
relationship: RO:0002309 CHEBI:7554 ! has exposure stimulus nicosulfuron

[Term]
id: ECTO:9000784
name: exposure to mecoprop
def: "An exposure to mecoprop." []
synonym: "mecoprop exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75711 ! has exposure stimulus mecoprop
relationship: RO:0002309 CHEBI:75711 ! has exposure stimulus mecoprop

[Term]
id: ECTO:9000785
name: exposure to triphenylmethane
def: "An exposure to triphenylmethane." []
synonym: "triphenylmethane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76212 ! has exposure stimulus triphenylmethane
relationship: RO:0002309 CHEBI:76212 ! has exposure stimulus triphenylmethane

[Term]
id: ECTO:9000786
name: exposure to N-nitrosopiperidine
def: "An exposure to N-nitrosopiperidine." []
synonym: "N-nitrosopiperidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76324 ! has exposure stimulus N-nitrosopiperidine
relationship: RO:0002309 CHEBI:76324 ! has exposure stimulus N-nitrosopiperidine

[Term]
id: ECTO:9000787
name: exposure to 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
def: "An exposure to 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole." []
synonym: "6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77278 ! has exposure stimulus 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
relationship: RO:0002309 CHEBI:77278 ! has exposure stimulus 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole

[Term]
id: ECTO:9000788
name: exposure to dexamisole
def: "An exposure to dexamisole." []
synonym: "dexamisole exposure" EXACT []
is_a: ECTO:9000787 ! exposure to 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77282 ! has exposure stimulus dexamisole
relationship: RO:0002309 CHEBI:77282 ! has exposure stimulus dexamisole

[Term]
id: ECTO:9000789
name: exposure to orbencarb
def: "An exposure to orbencarb." []
synonym: "orbencarb exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7778 ! has exposure stimulus orbencarb
relationship: RO:0002309 CHEBI:7778 ! has exposure stimulus orbencarb

[Term]
id: ECTO:9000790
name: exposure to toxaphene
def: "An exposure to toxaphene." []
synonym: "toxaphene exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77850 ! has exposure stimulus toxaphene
relationship: RO:0002309 CHEBI:77850 ! has exposure stimulus toxaphene

[Term]
id: ECTO:9000791
name: exposure to oseltamivir
def: "An exposure to oseltamivir." []
synonym: "oseltamivir exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7798 ! has exposure stimulus oseltamivir
relationship: RO:0002309 CHEBI:7798 ! has exposure stimulus oseltamivir

[Term]
id: ECTO:9000792
name: exposure to oxazepam
def: "An exposure to oxazepam." []
synonym: "oxazepam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7823 ! has exposure stimulus oxazepam
relationship: RO:0002309 CHEBI:7823 ! has exposure stimulus oxazepam

[Term]
id: ECTO:9000793
name: exposure to cumene hydroperoxide
def: "An exposure to cumene hydroperoxide." []
synonym: "cumene hydroperoxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000222 ! exposure to hydroperoxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78673 ! has exposure stimulus cumene hydroperoxide
relationship: RO:0002309 CHEBI:78673 ! has exposure stimulus cumene hydroperoxide

[Term]
id: ECTO:9000794
name: exposure to pyraclostrobin
def: "An exposure to pyraclostrobin." []
synonym: "pyraclostrobin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78780 ! has exposure stimulus pyraclostrobin
relationship: RO:0002309 CHEBI:78780 ! has exposure stimulus pyraclostrobin

[Term]
id: ECTO:9000795
name: exposure to pantoprazole
def: "An exposure to pantoprazole." []
synonym: "pantoprazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7915 ! has exposure stimulus pantoprazole
relationship: RO:0002309 CHEBI:7915 ! has exposure stimulus pantoprazole

[Term]
id: ECTO:9000796
name: exposure to 3,4,4',5-Tetrachlorobiphenyl
def: "An exposure to 3,4,4',5-Tetrachlorobiphenyl." []
synonym: "3,4,4',5-Tetrachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000653 ! exposure to tetrachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81516 ! has exposure stimulus 3,4,4',5-Tetrachlorobiphenyl
relationship: RO:0002309 CHEBI:81516 ! has exposure stimulus 3,4,4',5-Tetrachlorobiphenyl

[Term]
id: ECTO:9000797
name: exposure to 3,4,5,3',4',5'-Hexachlorobiphenyl
def: "An exposure to 3,4,5,3',4',5'-Hexachlorobiphenyl." []
synonym: "3,4,5,3',4',5'-Hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81517 ! has exposure stimulus 3,4,5,3',4',5'-Hexachlorobiphenyl
relationship: RO:0002309 CHEBI:81517 ! has exposure stimulus 3,4,5,3',4',5'-Hexachlorobiphenyl

[Term]
id: ECTO:9000798
name: exposure to 2,3,4,3',4'-Pentachlorobiphenyl
def: "An exposure to 2,3,4,3',4'-Pentachlorobiphenyl." []
synonym: "2,3,4,3',4'-Pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000654 ! exposure to pentachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81518 ! has exposure stimulus 2,3,4,3',4'-Pentachlorobiphenyl
relationship: RO:0002309 CHEBI:81518 ! has exposure stimulus 2,3,4,3',4'-Pentachlorobiphenyl

[Term]
id: ECTO:9000799
name: exposure to 2,3,4,4',5-Pentachlorobiphenyl
def: "An exposure to 2,3,4,4',5-Pentachlorobiphenyl." []
synonym: "2,3,4,4',5-Pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000654 ! exposure to pentachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81519 ! has exposure stimulus 2,3,4,4',5-Pentachlorobiphenyl
relationship: RO:0002309 CHEBI:81519 ! has exposure stimulus 2,3,4,4',5-Pentachlorobiphenyl

[Term]
id: ECTO:9000800
name: exposure to 2,3',4,4',5-Pentachlorobiphenyl
def: "An exposure to 2,3',4,4',5-Pentachlorobiphenyl." []
synonym: "2,3',4,4',5-Pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000654 ! exposure to pentachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81520 ! has exposure stimulus 2,3',4,4',5-Pentachlorobiphenyl
relationship: RO:0002309 CHEBI:81520 ! has exposure stimulus 2,3',4,4',5-Pentachlorobiphenyl

[Term]
id: ECTO:9000801
name: exposure to 2,3',4,4',5'-Pentachlorobiphenyl
def: "An exposure to 2,3',4,4',5'-Pentachlorobiphenyl." []
synonym: "2,3',4,4',5'-Pentachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000654 ! exposure to pentachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81521 ! has exposure stimulus 2,3',4,4',5'-Pentachlorobiphenyl
relationship: RO:0002309 CHEBI:81521 ! has exposure stimulus 2,3',4,4',5'-Pentachlorobiphenyl

[Term]
id: ECTO:9000802
name: exposure to 2,3,3',4,4',5-Hexachlorobiphenyl
def: "An exposure to 2,3,3',4,4',5-Hexachlorobiphenyl." []
synonym: "2,3,3',4,4',5-Hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81522 ! has exposure stimulus 2,3,3',4,4',5-Hexachlorobiphenyl
relationship: RO:0002309 CHEBI:81522 ! has exposure stimulus 2,3,3',4,4',5-Hexachlorobiphenyl

[Term]
id: ECTO:9000803
name: exposure to 2,3,3',4,4',5'-Hexachlorobiphenyl
def: "An exposure to 2,3,3',4,4',5'-Hexachlorobiphenyl." []
synonym: "2,3,3',4,4',5'-Hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81523 ! has exposure stimulus 2,3,3',4,4',5'-Hexachlorobiphenyl
relationship: RO:0002309 CHEBI:81523 ! has exposure stimulus 2,3,3',4,4',5'-Hexachlorobiphenyl

[Term]
id: ECTO:9000804
name: exposure to 2,3',4,4',5,5'-Hexachlorobiphenyl
def: "An exposure to 2,3',4,4',5,5'-Hexachlorobiphenyl." []
synonym: "2,3',4,4',5,5'-Hexachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000655 ! exposure to hexachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81524 ! has exposure stimulus 2,3',4,4',5,5'-Hexachlorobiphenyl
relationship: RO:0002309 CHEBI:81524 ! has exposure stimulus 2,3',4,4',5,5'-Hexachlorobiphenyl

[Term]
id: ECTO:9000805
name: exposure to 2,3,3',4,4',5,5'-Heptachlorobiphenyl
def: "An exposure to 2,3,3',4,4',5,5'-Heptachlorobiphenyl." []
synonym: "2,3,3',4,4',5,5'-Heptachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000882 ! exposure to heptachlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81525 ! has exposure stimulus 2,3,3',4,4',5,5'-Heptachlorobiphenyl
relationship: RO:0002309 CHEBI:81525 ! has exposure stimulus 2,3,3',4,4',5,5'-Heptachlorobiphenyl

[Term]
id: ECTO:9000806
name: exposure to asulam
def: "An exposure to asulam." []
synonym: "asulam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81696 ! has exposure stimulus asulam
relationship: RO:0002309 CHEBI:81696 ! has exposure stimulus asulam

[Term]
id: ECTO:9000807
name: exposure to desmedipham
def: "An exposure to desmedipham." []
synonym: "desmedipham exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81733 ! has exposure stimulus desmedipham
relationship: RO:0002309 CHEBI:81733 ! has exposure stimulus desmedipham

[Term]
id: ECTO:9000808
name: exposure to phenmedipham
def: "An exposure to phenmedipham." []
synonym: "phenmedipham exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81734 ! has exposure stimulus phenmedipham
relationship: RO:0002309 CHEBI:81734 ! has exposure stimulus phenmedipham

[Term]
id: ECTO:9000809
name: exposure to cyproconazole
def: "An exposure to cyproconazole." []
synonym: "cyproconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81758 ! has exposure stimulus cyproconazole
relationship: RO:0002309 CHEBI:81758 ! has exposure stimulus cyproconazole

[Term]
id: ECTO:9000810
name: exposure to difenoconazole
def: "An exposure to difenoconazole." []
synonym: "difenoconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81760 ! has exposure stimulus difenoconazole
relationship: RO:0002309 CHEBI:81760 ! has exposure stimulus difenoconazole

[Term]
id: ECTO:9000811
name: exposure to tebuconazole
def: "An exposure to tebuconazole." []
synonym: "tebuconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81781 ! has exposure stimulus tebuconazole
relationship: RO:0002309 CHEBI:81781 ! has exposure stimulus tebuconazole

[Term]
id: ECTO:9000812
name: exposure to cymoxanil
def: "An exposure to cymoxanil." []
synonym: "cymoxanil exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81788 ! has exposure stimulus cymoxanil
relationship: RO:0002309 CHEBI:81788 ! has exposure stimulus cymoxanil

[Term]
id: ECTO:9000813
name: exposure to dimethenamid
def: "An exposure to dimethenamid." []
synonym: "dimethenamid exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81789 ! has exposure stimulus dimethenamid
relationship: RO:0002309 CHEBI:81789 ! has exposure stimulus dimethenamid

[Term]
id: ECTO:9000814
name: exposure to fluazifop
def: "An exposure to fluazifop." []
synonym: "fluazifop exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81805 ! has exposure stimulus fluazifop
relationship: RO:0002309 CHEBI:81805 ! has exposure stimulus fluazifop

[Term]
id: ECTO:9000815
name: exposure to 2-methyl-4-chlorophenoxybutyric acid
def: "An exposure to 2-methyl-4-chlorophenoxybutyric acid." []
synonym: "2-methyl-4-chlorophenoxybutyric acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81806 ! has exposure stimulus 2-methyl-4-chlorophenoxybutyric acid
relationship: RO:0002309 CHEBI:81806 ! has exposure stimulus 2-methyl-4-chlorophenoxybutyric acid

[Term]
id: ECTO:9000816
name: exposure to trinexapac-ethyl
def: "An exposure to trinexapac-ethyl." []
synonym: "trinexapac-ethyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81817 ! has exposure stimulus trinexapac-ethyl
relationship: RO:0002309 CHEBI:81817 ! has exposure stimulus trinexapac-ethyl

[Term]
id: ECTO:9000817
name: exposure to ioxynil
def: "An exposure to ioxynil." []
synonym: "ioxynil exposure" EXACT []
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9001353 ! exposure to phenols
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81821 ! has exposure stimulus ioxynil
relationship: RO:0002309 CHEBI:81821 ! has exposure stimulus ioxynil

[Term]
id: ECTO:9000818
name: exposure to boscalid
def: "An exposure to boscalid." []
synonym: "boscalid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81822 ! has exposure stimulus boscalid
relationship: RO:0002309 CHEBI:81822 ! has exposure stimulus boscalid

[Term]
id: ECTO:9000819
name: exposure to diflufenican
def: "An exposure to diflufenican." []
synonym: "diflufenican exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81824 ! has exposure stimulus diflufenican
relationship: RO:0002309 CHEBI:81824 ! has exposure stimulus diflufenican

[Term]
id: ECTO:9000820
name: exposure to chloridazon
def: "An exposure to chloridazon." []
synonym: "chloridazon exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81838 ! has exposure stimulus chloridazon
relationship: RO:0002309 CHEBI:81838 ! has exposure stimulus chloridazon

[Term]
id: ECTO:9000821
name: exposure to fluazinam
def: "An exposure to fluazinam." []
synonym: "fluazinam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81843 ! has exposure stimulus fluazinam
relationship: RO:0002309 CHEBI:81843 ! has exposure stimulus fluazinam

[Term]
id: ECTO:9000822
name: exposure to dimethomorph
def: "An exposure to dimethomorph." []
synonym: "dimethomorph exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81848 ! has exposure stimulus dimethomorph
relationship: RO:0002309 CHEBI:81848 ! has exposure stimulus dimethomorph

[Term]
id: ECTO:9000823
name: exposure to dicamba
def: "An exposure to dicamba." []
synonym: "dicamba exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81856 ! has exposure stimulus dicamba
relationship: RO:0002309 CHEBI:81856 ! has exposure stimulus dicamba

[Term]
id: ECTO:9000824
name: exposure to imazamox
def: "An exposure to imazamox." []
synonym: "imazamox exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81857 ! has exposure stimulus imazamox
relationship: RO:0002309 CHEBI:81857 ! has exposure stimulus imazamox

[Term]
id: ECTO:9000825
name: exposure to dimethachlor
def: "An exposure to dimethachlor." []
synonym: "dimethachlor exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81911 ! has exposure stimulus dimethachlor
relationship: RO:0002309 CHEBI:81911 ! has exposure stimulus dimethachlor

[Term]
id: ECTO:9000826
name: exposure to fenpropidin
def: "An exposure to fenpropidin." []
synonym: "fenpropidin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81917 ! has exposure stimulus fenpropidin
relationship: RO:0002309 CHEBI:81917 ! has exposure stimulus fenpropidin

[Term]
id: ECTO:9000827
name: exposure to flufenacet
def: "An exposure to flufenacet." []
synonym: "flufenacet exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81920 ! has exposure stimulus flufenacet
relationship: RO:0002309 CHEBI:81920 ! has exposure stimulus flufenacet

[Term]
id: ECTO:9000828
name: exposure to flusilazole
def: "An exposure to flusilazole." []
synonym: "flusilazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81922 ! has exposure stimulus flusilazole
relationship: RO:0002309 CHEBI:81922 ! has exposure stimulus flusilazole

[Term]
id: ECTO:9000829
name: exposure to octhilinone
def: "An exposure to octhilinone." []
synonym: "octhilinone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81936 ! has exposure stimulus octhilinone
relationship: RO:0002309 CHEBI:81936 ! has exposure stimulus octhilinone

[Term]
id: ECTO:9000830
name: exposure to prosulfocarb
def: "An exposure to prosulfocarb." []
synonym: "prosulfocarb exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81941 ! has exposure stimulus prosulfocarb
relationship: RO:0002309 CHEBI:81941 ! has exposure stimulus prosulfocarb

[Term]
id: ECTO:9000831
name: exposure to sulfluramid
def: "An exposure to sulfluramid." []
synonym: "sulfluramid exposure" EXACT []
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81945 ! has exposure stimulus sulfluramid
relationship: RO:0002309 CHEBI:81945 ! has exposure stimulus sulfluramid

[Term]
id: ECTO:9000832
name: exposure to terbumeton
def: "An exposure to terbumeton." []
synonym: "terbumeton exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81947 ! has exposure stimulus terbumeton
relationship: RO:0002309 CHEBI:81947 ! has exposure stimulus terbumeton

[Term]
id: ECTO:9000833
name: exposure to chlorotoluron
def: "An exposure to chlorotoluron." []
synonym: "chlorotoluron exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81981 ! has exposure stimulus chlorotoluron
relationship: RO:0002309 CHEBI:81981 ! has exposure stimulus chlorotoluron

[Term]
id: ECTO:9000834
name: exposure to ethofumesate
def: "An exposure to ethofumesate." []
synonym: "ethofumesate exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81990 ! has exposure stimulus ethofumesate
relationship: RO:0002309 CHEBI:81990 ! has exposure stimulus ethofumesate

[Term]
id: ECTO:9000835
name: exposure to fluroxypyr
def: "An exposure to fluroxypyr." []
synonym: "fluroxypyr exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82017 ! has exposure stimulus fluroxypyr
relationship: RO:0002309 CHEBI:82017 ! has exposure stimulus fluroxypyr

[Term]
id: ECTO:9000836
name: exposure to iprovalicarb
def: "An exposure to iprovalicarb." []
synonym: "iprovalicarb exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82023 ! has exposure stimulus iprovalicarb
relationship: RO:0002309 CHEBI:82023 ! has exposure stimulus iprovalicarb

[Term]
id: ECTO:9000837
name: exposure to napropamide
def: "An exposure to napropamide." []
synonym: "napropamide exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82025 ! has exposure stimulus napropamide
relationship: RO:0002309 CHEBI:82025 ! has exposure stimulus napropamide

[Term]
id: ECTO:9000838
name: exposure to propamocarb
def: "An exposure to propamocarb." []
synonym: "propamocarb exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82033 ! has exposure stimulus propamocarb
relationship: RO:0002309 CHEBI:82033 ! has exposure stimulus propamocarb

[Term]
id: ECTO:9000839
name: exposure to propaquizafop
def: "An exposure to propaquizafop." []
synonym: "propaquizafop exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82034 ! has exposure stimulus propaquizafop
relationship: RO:0002309 CHEBI:82034 ! has exposure stimulus propaquizafop

[Term]
id: ECTO:9000840
name: exposure to tebutam
def: "An exposure to tebutam." []
synonym: "tebutam exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82043 ! has exposure stimulus tebutam
relationship: RO:0002309 CHEBI:82043 ! has exposure stimulus tebutam

[Term]
id: ECTO:9000841
name: exposure to atraton
def: "An exposure to atraton." []
synonym: "atraton exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82220 ! has exposure stimulus atraton
relationship: RO:0002309 CHEBI:82220 ! has exposure stimulus atraton

[Term]
id: ECTO:9000842
name: exposure to secbumeton
def: "An exposure to secbumeton." []
synonym: "secbumeton exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82228 ! has exposure stimulus secbumeton
relationship: RO:0002309 CHEBI:82228 ! has exposure stimulus secbumeton

[Term]
id: ECTO:9000843
name: exposure to pirimicarb
def: "An exposure to pirimicarb." []
synonym: "pirimicarb exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8248 ! has exposure stimulus pirimicarb
relationship: RO:0002309 CHEBI:8248 ! has exposure stimulus pirimicarb

[Term]
id: ECTO:9000844
name: exposure to 3-iodoprop-2-yn-1-yl butylcarbamate
def: "An exposure to 3-iodoprop-2-yn-1-yl butylcarbamate." []
synonym: "3-iodoprop-2-yn-1-yl butylcarbamate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83279 ! has exposure stimulus 3-iodoprop-2-yn-1-yl butylcarbamate
relationship: RO:0002309 CHEBI:83279 ! has exposure stimulus 3-iodoprop-2-yn-1-yl butylcarbamate

[Term]
id: ECTO:9000845
name: exposure to thifensulfuron-methyl
def: "An exposure to thifensulfuron-methyl." []
synonym: "thifensulfuron-methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83453 ! has exposure stimulus thifensulfuron-methyl
relationship: RO:0002309 CHEBI:83453 ! has exposure stimulus thifensulfuron-methyl

[Term]
id: ECTO:9000846
name: exposure to 5-methyl-1H-benzotriazole
def: "An exposure to 5-methyl-1H-benzotriazole." []
synonym: "5-methyl-1H-benzotriazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83455 ! has exposure stimulus 5-methyl-1H-benzotriazole
relationship: RO:0002309 CHEBI:83455 ! has exposure stimulus 5-methyl-1H-benzotriazole

[Term]
id: ECTO:9000847
name: exposure to sulcotrione
def: "An exposure to sulcotrione." []
synonym: "sulcotrione exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83465 ! has exposure stimulus sulcotrione
relationship: RO:0002309 CHEBI:83465 ! has exposure stimulus sulcotrione

[Term]
id: ECTO:9000848
name: exposure to perfluoropentanoic acid
def: "An exposure to perfluoropentanoic acid." []
synonym: "perfluoropentanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83491 ! has exposure stimulus perfluoropentanoic acid
relationship: RO:0002309 CHEBI:83491 ! has exposure stimulus perfluoropentanoic acid

[Term]
id: ECTO:9000849
name: exposure to perfluorohexanoic acid
def: "An exposure to perfluorohexanoic acid." []
synonym: "perfluorohexanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83492 ! has exposure stimulus perfluorohexanoic acid
relationship: RO:0002309 CHEBI:83492 ! has exposure stimulus perfluorohexanoic acid

[Term]
id: ECTO:9000850
name: exposure to perfluoroundecanoic acid
def: "An exposure to perfluoroundecanoic acid." []
synonym: "perfluoroundecanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83493 ! has exposure stimulus perfluoroundecanoic acid
relationship: RO:0002309 CHEBI:83493 ! has exposure stimulus perfluoroundecanoic acid

[Term]
id: ECTO:9000851
name: exposure to 6:2 fluorotelomer unsaturated carboxylic acid
def: "An exposure to 6:2 fluorotelomer unsaturated carboxylic acid." []
synonym: "6:2 fluorotelomer unsaturated carboxylic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83494 ! has exposure stimulus 6:2 fluorotelomer unsaturated carboxylic acid
relationship: RO:0002309 CHEBI:83494 ! has exposure stimulus 6:2 fluorotelomer unsaturated carboxylic acid

[Term]
id: ECTO:9000852
name: exposure to 8:2 fluorotelomer unsaturated carboxylic acid
def: "An exposure to 8:2 fluorotelomer unsaturated carboxylic acid." []
synonym: "8:2 fluorotelomer unsaturated carboxylic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83495 ! has exposure stimulus 8:2 fluorotelomer unsaturated carboxylic acid
relationship: RO:0002309 CHEBI:83495 ! has exposure stimulus 8:2 fluorotelomer unsaturated carboxylic acid

[Term]
id: ECTO:9000853
name: exposure to climbazole
def: "An exposure to climbazole." []
synonym: "climbazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83499 ! has exposure stimulus climbazole
relationship: RO:0002309 CHEBI:83499 ! has exposure stimulus climbazole

[Term]
id: ECTO:9000854
name: exposure to tritosulfuron
def: "An exposure to tritosulfuron." []
synonym: "tritosulfuron exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83500 ! has exposure stimulus tritosulfuron
relationship: RO:0002309 CHEBI:83500 ! has exposure stimulus tritosulfuron

[Term]
id: ECTO:9000855
name: exposure to acesulfame
def: "An exposure to acesulfame." []
synonym: "acesulfame exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83501 ! has exposure stimulus acesulfame
relationship: RO:0002309 CHEBI:83501 ! has exposure stimulus acesulfame

[Term]
id: ECTO:9000856
name: exposure to foramsulfuron
def: "An exposure to foramsulfuron." []
synonym: "foramsulfuron exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83502 ! has exposure stimulus foramsulfuron
relationship: RO:0002309 CHEBI:83502 ! has exposure stimulus foramsulfuron

[Term]
id: ECTO:9000857
name: exposure to neotame
def: "An exposure to neotame." []
synonym: "neotame exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83503 ! has exposure stimulus neotame
relationship: RO:0002309 CHEBI:83503 ! has exposure stimulus neotame

[Term]
id: ECTO:9000858
name: exposure to perfluorooctane sulfonamidoacetic acid
def: "An exposure to perfluorooctane sulfonamidoacetic acid." []
synonym: "perfluorooctane sulfonamidoacetic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83505 ! has exposure stimulus perfluorooctane sulfonamidoacetic acid
relationship: RO:0002309 CHEBI:83505 ! has exposure stimulus perfluorooctane sulfonamidoacetic acid

[Term]
id: ECTO:9000859
name: exposure to N-methylperfluorooctane sulfonamidoacetic acid
def: "An exposure to N-methylperfluorooctane sulfonamidoacetic acid." []
synonym: "N-methylperfluorooctane sulfonamidoacetic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83506 ! has exposure stimulus N-methylperfluorooctane sulfonamidoacetic acid
relationship: RO:0002309 CHEBI:83506 ! has exposure stimulus N-methylperfluorooctane sulfonamidoacetic acid

[Term]
id: ECTO:9000860
name: exposure to N-ethylperfluorooctane sulfonamidoacetic acid
def: "An exposure to N-ethylperfluorooctane sulfonamidoacetic acid." []
synonym: "N-ethylperfluorooctane sulfonamidoacetic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83507 ! has exposure stimulus N-ethylperfluorooctane sulfonamidoacetic acid
relationship: RO:0002309 CHEBI:83507 ! has exposure stimulus N-ethylperfluorooctane sulfonamidoacetic acid

[Term]
id: ECTO:9000861
name: exposure to perfluorooctyl phosphate
def: "An exposure to perfluorooctyl phosphate." []
synonym: "perfluorooctyl phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83508 ! has exposure stimulus perfluorooctyl phosphate
relationship: RO:0002309 CHEBI:83508 ! has exposure stimulus perfluorooctyl phosphate

[Term]
id: ECTO:9000862
name: exposure to iooxitalamic acid
def: "An exposure to iooxitalamic acid." []
synonym: "iooxitalamic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83517 ! has exposure stimulus iooxitalamic acid
relationship: RO:0002309 CHEBI:83517 ! has exposure stimulus iooxitalamic acid

[Term]
id: ECTO:9000863
name: exposure to 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone
def: "An exposure to 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone." []
synonym: "4,5-dichloro-2-n-octyl-3(2H)-isothiazolone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83518 ! has exposure stimulus 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone
relationship: RO:0002309 CHEBI:83518 ! has exposure stimulus 4,5-dichloro-2-n-octyl-3(2H)-isothiazolone

[Term]
id: ECTO:9000864
name: exposure to sebuthylazine
def: "An exposure to sebuthylazine." []
synonym: "sebuthylazine exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83521 ! has exposure stimulus sebuthylazine
relationship: RO:0002309 CHEBI:83521 ! has exposure stimulus sebuthylazine

[Term]
id: ECTO:9000865
name: exposure to pethoxamide
def: "An exposure to pethoxamide." []
synonym: "pethoxamide exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83523 ! has exposure stimulus pethoxamide
relationship: RO:0002309 CHEBI:83523 ! has exposure stimulus pethoxamide

[Term]
id: ECTO:9000866
name: exposure to pinoxaden
def: "An exposure to pinoxaden." []
synonym: "pinoxaden exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83524 ! has exposure stimulus pinoxaden
relationship: RO:0002309 CHEBI:83524 ! has exposure stimulus pinoxaden

[Term]
id: ECTO:9000867
name: exposure to moclobemide
def: "An exposure to moclobemide." []
synonym: "moclobemide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83531 ! has exposure stimulus moclobemide
relationship: RO:0002309 CHEBI:83531 ! has exposure stimulus moclobemide

[Term]
id: ECTO:9000868
name: exposure to neohesperidin dihydrochalcone
def: "An exposure to neohesperidin dihydrochalcone." []
synonym: "neohesperidin dihydrochalcone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83535 ! has exposure stimulus neohesperidin dihydrochalcone
relationship: RO:0002309 CHEBI:83535 ! has exposure stimulus neohesperidin dihydrochalcone

[Term]
id: ECTO:9000869
name: exposure to 1-(3-(trifluoromethyl)phenyl)piperazine
def: "An exposure to 1-(3-(trifluoromethyl)phenyl)piperazine." []
synonym: "1-(3-(trifluoromethyl)phenyl)piperazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83536 ! has exposure stimulus 1-(3-(trifluoromethyl)phenyl)piperazine
relationship: RO:0002309 CHEBI:83536 ! has exposure stimulus 1-(3-(trifluoromethyl)phenyl)piperazine

[Term]
id: ECTO:9000870
name: exposure to 1-benzylpiperazine
def: "An exposure to 1-benzylpiperazine." []
synonym: "1-benzylpiperazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83537 ! has exposure stimulus 1-benzylpiperazine
relationship: RO:0002309 CHEBI:83537 ! has exposure stimulus 1-benzylpiperazine

[Term]
id: ECTO:9000871
name: exposure to bisperfluorooctyl phosphate
def: "An exposure to bisperfluorooctyl phosphate." []
synonym: "bisperfluorooctyl phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83539 ! has exposure stimulus bisperfluorooctyl phosphate
relationship: RO:0002309 CHEBI:83539 ! has exposure stimulus bisperfluorooctyl phosphate

[Term]
id: ECTO:9000872
name: exposure to bisperfluorodecyl phosphate
def: "An exposure to bisperfluorodecyl phosphate." []
synonym: "bisperfluorodecyl phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83540 ! has exposure stimulus bisperfluorodecyl phosphate
relationship: RO:0002309 CHEBI:83540 ! has exposure stimulus bisperfluorodecyl phosphate

[Term]
id: ECTO:9000873
name: exposure to perfluorodecyl phosphate
def: "An exposure to perfluorodecyl phosphate." []
synonym: "perfluorodecyl phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83541 ! has exposure stimulus perfluorodecyl phosphate
relationship: RO:0002309 CHEBI:83541 ! has exposure stimulus perfluorodecyl phosphate

[Term]
id: ECTO:9000874
name: exposure to pendimethalin
def: "An exposure to pendimethalin." []
synonym: "pendimethalin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83569 ! has exposure stimulus pendimethalin
relationship: RO:0002309 CHEBI:83569 ! has exposure stimulus pendimethalin

[Term]
id: ECTO:9000875
name: exposure to prednisolone
def: "An exposure to prednisolone." []
synonym: "prednisolone exposure" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8378 ! has exposure stimulus prednisolone
relationship: RO:0002309 CHEBI:8378 ! has exposure stimulus prednisolone

[Term]
id: ECTO:9000876
name: exposure to primidone
def: "An exposure to primidone." []
synonym: "primidone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8412 ! has exposure stimulus primidone
relationship: RO:0002309 CHEBI:8412 ! has exposure stimulus primidone

[Term]
id: ECTO:9000877
name: exposure to quinmerac
def: "An exposure to quinmerac." []
synonym: "quinmerac exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84199 ! has exposure stimulus quinmerac
relationship: RO:0002309 CHEBI:84199 ! has exposure stimulus quinmerac

[Term]
id: ECTO:9000878
name: exposure to prochloraz
def: "An exposure to prochloraz." []
synonym: "prochloraz exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8434 ! has exposure stimulus prochloraz
relationship: RO:0002309 CHEBI:8434 ! has exposure stimulus prochloraz

[Term]
id: ECTO:9000879
name: exposure to propiconazole
def: "An exposure to propiconazole." []
synonym: "propiconazole exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8489 ! has exposure stimulus propiconazole
relationship: RO:0002309 CHEBI:8489 ! has exposure stimulus propiconazole

[Term]
id: ECTO:9000880
name: exposure to propranolol
def: "An exposure to propranolol." []
synonym: "propranolol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8499 ! has exposure stimulus propranolol
relationship: RO:0002309 CHEBI:8499 ! has exposure stimulus propranolol

[Term]
id: ECTO:9000881
name: exposure to flumequine
def: "An exposure to flumequine." []
synonym: "flumequine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85267 ! has exposure stimulus flumequine
relationship: RO:0002309 CHEBI:85267 ! has exposure stimulus flumequine

[Term]
id: ECTO:9000882
name: exposure to heptachlorobiphenyl
def: "An exposure to heptachlorobiphenyl." []
synonym: "heptachlorobiphenyl exposure" EXACT []
is_a: ECTO:9000068 ! exposure to polychlorobiphenyl
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85782 ! has exposure stimulus heptachlorobiphenyl
relationship: RO:0002309 CHEBI:85782 ! has exposure stimulus heptachlorobiphenyl

[Term]
id: ECTO:9000883
name: exposure to pyrimethanil
def: "An exposure to pyrimethanil." []
synonym: "pyrimethanil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8674 ! has exposure stimulus pyrimethanil
relationship: RO:0002309 CHEBI:8674 ! has exposure stimulus pyrimethanil

[Term]
id: ECTO:9000884
name: exposure to acid red 4
def: "An exposure to acid red 4." []
synonym: "acid red 4 exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87094 ! has exposure stimulus acid red 4
relationship: RO:0002309 CHEBI:87094 ! has exposure stimulus acid red 4

[Term]
id: ECTO:9000885
name: exposure to (R)-(+)-propranolol
def: "An exposure to (R)-(+)-propranolol." []
synonym: "(R)-(+)-propranolol exposure" EXACT []
is_a: ECTO:9000880 ! exposure to propranolol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8736 ! has exposure stimulus (R)-(+)-propranolol
relationship: RO:0002309 CHEBI:8736 ! has exposure stimulus (R)-(+)-propranolol

[Term]
id: ECTO:9000886
name: exposure to (R)-salbutamol
def: "An exposure to (R)-salbutamol." []
synonym: "(R)-salbutamol exposure" EXACT []
is_a: ECTO:9000565 ! exposure to albuterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8746 ! has exposure stimulus (R)-salbutamol
relationship: RO:0002309 CHEBI:8746 ! has exposure stimulus (R)-salbutamol

[Term]
id: ECTO:9000887
name: exposure to ranitidine
def: "An exposure to ranitidine." []
synonym: "ranitidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8776 ! has exposure stimulus ranitidine
relationship: RO:0002309 CHEBI:8776 ! has exposure stimulus ranitidine

[Term]
id: ECTO:9000888
name: exposure to brilliant green
def: "An exposure to brilliant green." []
synonym: "brilliant green exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88173 ! has exposure stimulus brilliant green
relationship: RO:0002309 CHEBI:88173 ! has exposure stimulus brilliant green

[Term]
id: ECTO:9000889
name: exposure to brilliant green cation
def: "An exposure to brilliant green cation." []
synonym: "brilliant green cation exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88176 ! has exposure stimulus brilliant green cation
relationship: RO:0002309 CHEBI:88176 ! has exposure stimulus brilliant green cation

[Term]
id: ECTO:9000890
name: exposure to Sirius red 4B
def: "An exposure to Sirius red 4B." []
synonym: "Sirius red 4B exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88191 ! has exposure stimulus Sirius red 4B
relationship: RO:0002309 CHEBI:88191 ! has exposure stimulus Sirius red 4B

[Term]
id: ECTO:9000891
name: exposure to rimsulfuron
def: "An exposure to rimsulfuron." []
synonym: "rimsulfuron exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8866 ! has exposure stimulus rimsulfuron
relationship: RO:0002309 CHEBI:8866 ! has exposure stimulus rimsulfuron

[Term]
id: ECTO:9000892
name: exposure to perfluorododecanoic acid
def: "An exposure to perfluorododecanoic acid." []
synonym: "perfluorododecanoic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:90633 ! has exposure stimulus perfluorododecanoic acid
relationship: RO:0002309 CHEBI:90633 ! has exposure stimulus perfluorododecanoic acid

[Term]
id: ECTO:9000893
name: exposure to spironolactone
def: "An exposure to spironolactone." []
synonym: "spironolactone exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9241 ! has exposure stimulus spironolactone
relationship: RO:0002309 CHEBI:9241 ! has exposure stimulus spironolactone

[Term]
id: ECTO:9000894
name: exposure to spiroxamine
def: "An exposure to spiroxamine." []
synonym: "spiroxamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9242 ! has exposure stimulus spiroxamine
relationship: RO:0002309 CHEBI:9242 ! has exposure stimulus spiroxamine

[Term]
id: ECTO:9000895
name: exposure to sulfadiazine
def: "An exposure to sulfadiazine." []
synonym: "sulfadiazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9328 ! has exposure stimulus sulfadiazine
relationship: RO:0002309 CHEBI:9328 ! has exposure stimulus sulfadiazine

[Term]
id: ECTO:9000896
name: exposure to sulfamethoxazole
def: "An exposure to sulfamethoxazole." []
synonym: "sulfamethoxazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9332 ! has exposure stimulus sulfamethoxazole
relationship: RO:0002309 CHEBI:9332 ! has exposure stimulus sulfamethoxazole

[Term]
id: ECTO:9000897
name: exposure to sulfathiazole
def: "An exposure to sulfathiazole." []
synonym: "sulfathiazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9337 ! has exposure stimulus sulfathiazole
relationship: RO:0002309 CHEBI:9337 ! has exposure stimulus sulfathiazole

[Term]
id: ECTO:9000898
name: exposure to 2,6-dichlorobenzonitrile
def: "An exposure to 2,6-dichlorobenzonitrile." []
synonym: "2,6-dichlorobenzonitrile exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:943 ! has exposure stimulus 2,6-dichlorobenzonitrile
relationship: RO:0002309 CHEBI:943 ! has exposure stimulus 2,6-dichlorobenzonitrile

[Term]
id: ECTO:9000899
name: exposure to telmisartan
def: "An exposure to telmisartan." []
synonym: "telmisartan exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9434 ! has exposure stimulus telmisartan
relationship: RO:0002309 CHEBI:9434 ! has exposure stimulus telmisartan

[Term]
id: ECTO:9000900
name: exposure to tramadol
def: "An exposure to tramadol." []
synonym: "tramadol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9648 ! has exposure stimulus tramadol
relationship: RO:0002309 CHEBI:9648 ! has exposure stimulus tramadol

[Term]
id: ECTO:9000901
name: exposure to trichlopyr
def: "An exposure to trichlopyr." []
synonym: "trichlopyr exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9682 ! has exposure stimulus trichlopyr
relationship: RO:0002309 CHEBI:9682 ! has exposure stimulus trichlopyr

[Term]
id: ECTO:9000902
name: exposure to trimipramine
def: "An exposure to trimipramine." []
synonym: "trimipramine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9738 ! has exposure stimulus trimipramine
relationship: RO:0002309 CHEBI:9738 ! has exposure stimulus trimipramine

[Term]
id: ECTO:9000903
name: exposure to valsartan
def: "An exposure to valsartan." []
synonym: "valsartan exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9927 ! has exposure stimulus valsartan
relationship: RO:0002309 CHEBI:9927 ! has exposure stimulus valsartan

[Term]
id: ECTO:9000904
name: exposure to venlafaxine
def: "An exposure to venlafaxine." []
synonym: "venlafaxine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9943 ! has exposure stimulus venlafaxine
relationship: RO:0002309 CHEBI:9943 ! has exposure stimulus venlafaxine

[Term]
id: ECTO:9000905
name: obsolete verapamil exposure
is_obsolete: true
replaced_by: ECTO:9000014

[Term]
id: ECTO:9000906
name: exposure to phthalate ester
def: "An exposure to phthalate ester." []
synonym: "phthalate ester exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35484 ! has exposure stimulus phthalate ester
relationship: RO:0002309 CHEBI:35484 ! has exposure stimulus phthalate ester

[Term]
id: ECTO:9000907
name: exposure to Heptachlor epoxide
def: "An exposure to Heptachlor epoxide." []
synonym: "Heptachlor epoxide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34786 ! has exposure stimulus Heptachlor epoxide
relationship: RO:0002309 CHEBI:34786 ! has exposure stimulus Heptachlor epoxide

[Term]
id: ECTO:9000908
name: exposure to metallic antimony
def: "An exposure to antimony(0)." []
synonym: "antimony(0) exposure" EXACT []
is_a: ECTO:9000939 ! exposure to antimony
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30304 ! has exposure stimulus antimony(0)
relationship: RO:0002309 CHEBI:30304 ! has exposure stimulus antimony(0)

[Term]
id: ECTO:9000909
name: exposure to elemental thallium
def: "An exposure to elemental thallium." []
synonym: "elemental thallium exposure" EXACT []
is_a: ECTO:9001312 ! exposure to thallium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37113 ! has exposure stimulus elemental thallium
relationship: RO:0002309 CHEBI:37113 ! has exposure stimulus elemental thallium

[Term]
id: ECTO:9000910
name: obsolete uranium molecular entity exposure
is_obsolete: true
replaced_by: ECTO:9000105

[Term]
id: ECTO:9000911
name: exposure to fluorene
def: "An exposure to fluorene." []
synonym: "fluorene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28266 ! has exposure stimulus fluorene
relationship: RO:0002309 CHEBI:28266 ! has exposure stimulus fluorene

[Term]
id: ECTO:9000912
name: exposure to 1,1,1-trichloroethane
def: "An exposure to 1,1,1-trichloroethane." []
synonym: "1,1,1-trichloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36015 ! has exposure stimulus 1,1,1-trichloroethane
relationship: RO:0002309 CHEBI:36015 ! has exposure stimulus 1,1,1-trichloroethane

[Term]
id: ECTO:9000913
name: exposure to 1,1,2,2-tetrachloroethane
def: "An exposure to 1,1,2,2-tetrachloroethane." []
synonym: "1,1,2,2-tetrachloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36026 ! has exposure stimulus 1,1,2,2-tetrachloroethane
relationship: RO:0002309 CHEBI:36026 ! has exposure stimulus 1,1,2,2-tetrachloroethane

[Term]
id: ECTO:9000914
name: exposure to 1,1,2-trichloroethane
def: "An exposure to 1,1,2-trichloroethane." []
synonym: "1,1,2-trichloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36018 ! has exposure stimulus 1,1,2-trichloroethane
relationship: RO:0002309 CHEBI:36018 ! has exposure stimulus 1,1,2-trichloroethane

[Term]
id: ECTO:9000915
name: exposure to 1,1-Dichloroethane
def: "An exposure to 1,1-Dichloroethane." []
synonym: "1,1-Dichloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81599 ! has exposure stimulus 1,1-Dichloroethane
relationship: RO:0002309 CHEBI:81599 ! has exposure stimulus 1,1-Dichloroethane

[Term]
id: ECTO:9000916
name: exposure to 1,1-dichloroethene
def: "An exposure to 1,1-dichloroethene." []
synonym: "1,1-dichloroethene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34031 ! has exposure stimulus 1,1-dichloroethene
relationship: RO:0002309 CHEBI:34031 ! has exposure stimulus 1,1-dichloroethene

[Term]
id: ECTO:9000917
name: exposure to 1,2-Dibromo-3-chloropropane
def: "An exposure to 1,2-Dibromo-3-chloropropane." []
synonym: "1,2-Dibromo-3-chloropropane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34044 ! has exposure stimulus 1,2-Dibromo-3-chloropropane
relationship: RO:0002309 CHEBI:34044 ! has exposure stimulus 1,2-Dibromo-3-chloropropane

[Term]
id: ECTO:9000918
name: exposure to 1,2-dichlorobenzene
def: "An exposure to 1,2-dichlorobenzene." []
synonym: "1,2-dichlorobenzene exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35290 ! has exposure stimulus 1,2-dichlorobenzene
relationship: RO:0002309 CHEBI:35290 ! has exposure stimulus 1,2-dichlorobenzene

[Term]
id: ECTO:9000919
name: exposure to cis-1,2-dichloroethene
def: "An exposure to cis-1,2-dichloroethene." []
synonym: "cis-1,2-dichloroethene exposure" EXACT []
is_a: ECTO:9001069 ! exposure to 1,2-dichloroethene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28805 ! has exposure stimulus cis-1,2-dichloroethene
relationship: RO:0002309 CHEBI:28805 ! has exposure stimulus cis-1,2-dichloroethene

[Term]
id: ECTO:9000920
name: exposure to trans-1,2-dichloroethene
def: "An exposure to trans-1,2-dichloroethene." []
synonym: "trans-1,2-dichloroethene exposure" EXACT []
is_a: ECTO:9001069 ! exposure to 1,2-dichloroethene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29027 ! has exposure stimulus trans-1,2-dichloroethene
relationship: RO:0002309 CHEBI:29027 ! has exposure stimulus trans-1,2-dichloroethene

[Term]
id: ECTO:9000921
name: exposure to 1,2-Dichloropropane
def: "An exposure to rac-1,2-dichloropropane." []
synonym: "rac-1,2-dichloropropane exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82163 ! has exposure stimulus rac-1,2-dichloropropane
relationship: RO:0002309 CHEBI:82163 ! has exposure stimulus rac-1,2-dichloropropane

[Term]
id: ECTO:9000922
name: exposure to 2,5-Dimethylfuran
def: "An exposure to 2,5-dimethylfuran." []
synonym: "2,5-dimethylfuran exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:89052 ! has exposure stimulus 2,5-dimethylfuran
relationship: RO:0002309 CHEBI:89052 ! has exposure stimulus 2,5-dimethylfuran

[Term]
id: ECTO:9000923
name: exposure to dibromomethane
def: "An exposure to dibromomethane." []
synonym: "dibromomethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47077 ! has exposure stimulus dibromomethane
relationship: RO:0002309 CHEBI:47077 ! has exposure stimulus dibromomethane

[Term]
id: ECTO:9000924
name: exposure to hexachloroethane
def: "An exposure to hexachloroethane." []
synonym: "hexachloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39227 ! has exposure stimulus hexachloroethane
relationship: RO:0002309 CHEBI:39227 ! has exposure stimulus hexachloroethane

[Term]
id: ECTO:9000925
name: exposure to 2,2',4,4'-Tetrabromodiphenyl ether
def: "An exposure to 2,2',4,4'-Tetrabromodiphenyl ether." []
synonym: "2,2',4,4'-Tetrabromodiphenyl ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81584 ! has exposure stimulus 2,2',4,4'-Tetrabromodiphenyl ether
relationship: RO:0002309 CHEBI:81584 ! has exposure stimulus 2,2',4,4'-Tetrabromodiphenyl ether

[Term]
id: ECTO:9000926
name: exposure to 2,2',4,4',5-Pentabromodiphenyl ether
def: "An exposure to 2,4-dibromophenyl 2,4,5-tribromophenyl ether." []
synonym: "2,4-dibromophenyl 2,4,5-tribromophenyl ether exposure" EXACT []
is_a: ECTO:9001619 ! exposure to polybromodiphenyl ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81582 ! has exposure stimulus 2,4-dibromophenyl 2,4,5-tribromophenyl ether
relationship: RO:0002309 CHEBI:81582 ! has exposure stimulus 2,4-dibromophenyl 2,4,5-tribromophenyl ether

[Term]
id: ECTO:9000927
name: exposure to 2,2',4,4',5,5'-Hexabromodiphenyl ether
def: "An exposure to 2,2',4,4',5,5'-Hexabromodiphenyl ether." []
synonym: "2,2',4,4',5,5'-Hexabromodiphenyl ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81534 ! has exposure stimulus 2,2',4,4',5,5'-Hexabromodiphenyl ether
relationship: RO:0002309 CHEBI:81534 ! has exposure stimulus 2,2',4,4',5,5'-Hexabromodiphenyl ether

[Term]
id: ECTO:9000928
name: exposure to 2,2',4,4',5,6'-Hexabromodiphenyl ether
def: "An exposure to 2,2',4,4',5,6'-Hexabromodiphenyl ether." []
synonym: "2,2',4,4',5,6'-Hexabromodiphenyl ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81535 ! has exposure stimulus 2,2',4,4',5,6'-Hexabromodiphenyl ether
relationship: RO:0002309 CHEBI:81535 ! has exposure stimulus 2,2',4,4',5,6'-Hexabromodiphenyl ether

[Term]
id: ECTO:9000929
name: exposure to 2,2',3,4,4',5',6-Heptabromodiphenyl ether
def: "An exposure to 2,2',3,4,4',5',6-Heptabromodiphenyl ether." []
synonym: "2,2',3,4,4',5',6-Heptabromodiphenyl ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81537 ! has exposure stimulus 2,2',3,4,4',5',6-Heptabromodiphenyl ether
relationship: RO:0002309 CHEBI:81537 ! has exposure stimulus 2,2',3,4,4',5',6-Heptabromodiphenyl ether

[Term]
id: ECTO:9000930
name: exposure to paraben
def: "An exposure to paraben." []
synonym: "paraben exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85122 ! has exposure stimulus paraben
relationship: RO:0002309 CHEBI:85122 ! has exposure stimulus paraben

[Term]
id: ECTO:9000931
name: exposure to perchlorate
def: "An exposure to perchlorate." []
synonym: "perchlorate exposure" EXACT []
is_a: ECTO:9002504 ! exposure to chlorine oxoanion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49706 ! has exposure stimulus perchlorate
relationship: RO:0002309 CHEBI:49706 ! has exposure stimulus perchlorate

[Term]
id: ECTO:9000932
name: exposure to daidzein
def: "An exposure to daidzein." []
synonym: "daidzein exposure" EXACT []
is_a: ECTO:9000231 ! exposure to hydroxyisoflavone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28197 ! has exposure stimulus daidzein
relationship: RO:0002309 CHEBI:28197 ! has exposure stimulus daidzein

[Term]
id: ECTO:9000933
name: exposure to Enterodiol
def: "An exposure to Enterodiol." []
synonym: "Enterodiol exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81556 ! has exposure stimulus Enterodiol
relationship: RO:0002309 CHEBI:81556 ! has exposure stimulus Enterodiol

[Term]
id: ECTO:9000934
name: exposure to Enterolactone
def: "An exposure to Enterolactone." []
synonym: "Enterolactone exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81555 ! has exposure stimulus Enterolactone
relationship: RO:0002309 CHEBI:81555 ! has exposure stimulus Enterolactone

[Term]
id: ECTO:9000935
name: exposure to equol
def: "An exposure to equol." []
synonym: "equol exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34741 ! has exposure stimulus equol
relationship: RO:0002309 CHEBI:34741 ! has exposure stimulus equol

[Term]
id: ECTO:9000936
name: exposure to O-Desmethylangolensin
def: "An exposure to O-Desmethylangolensin." []
synonym: "O-Desmethylangolensin exposure" EXACT []
is_a: ECTO:9000251 ! exposure to stilbenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88902 ! has exposure stimulus O-Desmethylangolensin
relationship: RO:0002309 CHEBI:88902 ! has exposure stimulus O-Desmethylangolensin

[Term]
id: ECTO:9000937
name: exposure to Arsenobetaine
def: "An exposure to Arsenobetaine." []
synonym: "Arsenobetaine exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82392 ! has exposure stimulus Arsenobetaine
relationship: RO:0002309 CHEBI:82392 ! has exposure stimulus Arsenobetaine

[Term]
id: ECTO:9000938
name: exposure to dimethylarsinic acid
def: "An exposure to dimethylarsinic acid." []
synonym: "dimethylarsinic acid exposure" EXACT []
is_a: ECTO:9000534 ! exposure to organoarsenic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48765 ! has exposure stimulus dimethylarsinic acid
relationship: RO:0002309 CHEBI:48765 ! has exposure stimulus dimethylarsinic acid

[Term]
id: ECTO:9000939
name: exposure to antimony
def: "An exposure to antimony molecular entity." []
synonym: "antimony molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36919 ! has exposure stimulus antimony molecular entity
relationship: RO:0002309 CHEBI:36919 ! has exposure stimulus antimony molecular entity

[Term]
id: ECTO:9000940
name: exposure to barium
def: "An exposure to barium molecular entity." []
synonym: "barium molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37133 ! has exposure stimulus barium molecular entity
relationship: RO:0002309 CHEBI:37133 ! has exposure stimulus barium molecular entity

[Term]
id: ECTO:9000941
name: exposure to beryllium
def: "An exposure to beryllium molecular entity." []
synonym: "beryllium molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33780 ! has exposure stimulus beryllium molecular entity
relationship: RO:0002309 CHEBI:33780 ! has exposure stimulus beryllium molecular entity

[Term]
id: ECTO:9000943
name: exposure to cobalt
def: "An exposure to cobalt molecular entity." []
synonym: "cobalt molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33888 ! has exposure stimulus cobalt molecular entity
relationship: RO:0002309 CHEBI:33888 ! has exposure stimulus cobalt molecular entity

[Term]
id: ECTO:9000944
name: exposure to copper
def: "An exposure to copper molecular entity." []
synonym: "copper molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23377 ! has exposure stimulus copper molecular entity
relationship: RO:0002309 CHEBI:23377 ! has exposure stimulus copper molecular entity

[Term]
id: ECTO:9000945
name: exposure to lead
def: "An exposure to lead molecular entity." []
synonym: "lead molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33585 ! has exposure stimulus lead molecular entity
relationship: RO:0002309 CHEBI:33585 ! has exposure stimulus lead molecular entity

[Term]
id: ECTO:9000946
name: exposure to manganese
def: "An exposure to manganese molecular entity." []
synonym: "manganese molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25154 ! has exposure stimulus manganese molecular entity
relationship: RO:0002309 CHEBI:25154 ! has exposure stimulus manganese molecular entity

[Term]
id: ECTO:9000948
name: exposure to molybdenum
def: "An exposure to molybdenum molecular entity." []
synonym: "molybdenum molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25370 ! has exposure stimulus molybdenum molecular entity
relationship: RO:0002309 CHEBI:25370 ! has exposure stimulus molybdenum molecular entity

[Term]
id: ECTO:9000949
name: exposure to platinum
def: "An exposure to platinum molecular entity." []
synonym: "platinum molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33749 ! has exposure stimulus platinum molecular entity
relationship: RO:0002309 CHEBI:33749 ! has exposure stimulus platinum molecular entity

[Term]
id: ECTO:9000950
name: exposure to selenium
def: "An exposure to selenium molecular entity." []
synonym: "selenium molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26628 ! has exposure stimulus selenium molecular entity
relationship: RO:0002309 CHEBI:26628 ! has exposure stimulus selenium molecular entity

[Term]
id: ECTO:9000951
name: exposure to strontium
def: "An exposure to strontium molecular entity." []
synonym: "strontium molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37131 ! has exposure stimulus strontium molecular entity
relationship: RO:0002309 CHEBI:37131 ! has exposure stimulus strontium molecular entity

[Term]
id: ECTO:9000952
name: exposure to tin
def: "An exposure to tin molecular entity." []
synonym: "tin molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27008 ! has exposure stimulus tin molecular entity
relationship: RO:0002309 CHEBI:27008 ! has exposure stimulus tin molecular entity

[Term]
id: ECTO:9000953
name: exposure to tungsten
def: "An exposure to tungsten." []
synonym: "tungsten exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27998 ! has exposure stimulus tungsten
relationship: RO:0002309 CHEBI:27998 ! has exposure stimulus tungsten

[Term]
id: ECTO:9000954
name: exposure to zinc
def: "An exposure to zinc molecular entity." []
synonym: "zinc molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27364 ! has exposure stimulus zinc molecular entity
relationship: RO:0002309 CHEBI:27364 ! has exposure stimulus zinc molecular entity

[Term]
id: ECTO:9000955
name: exposure to methylparaben
def: "An exposure to methylparaben." []
synonym: "methylparaben exposure" EXACT []
is_a: ECTO:9000930 ! exposure to paraben
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31835 ! has exposure stimulus methylparaben
relationship: RO:0002309 CHEBI:31835 ! has exposure stimulus methylparaben

[Term]
id: ECTO:9000956
name: exposure to methylarsonic acid
def: "An exposure to methylarsonic acid." []
synonym: "methylarsonic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000534 ! exposure to organoarsenic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29852 ! has exposure stimulus methylarsonic acid
relationship: RO:0002309 CHEBI:29852 ! has exposure stimulus methylarsonic acid

[Term]
id: ECTO:9000957
name: exposure to abamectin
def: "An exposure to abamectin." []
synonym: "abamectin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39214 ! has exposure stimulus abamectin
relationship: RO:0002309 CHEBI:39214 ! has exposure stimulus abamectin

[Term]
id: ECTO:9000958
name: exposure to acephate
def: "An exposure to acephate." []
synonym: "acephate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34520 ! has exposure stimulus acephate
relationship: RO:0002309 CHEBI:34520 ! has exposure stimulus acephate

[Term]
id: ECTO:9000959
name: exposure to acetaldehyde
def: "An exposure to acetaldehyde." []
synonym: "acetaldehyde exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15343 ! has exposure stimulus acetaldehyde
relationship: RO:0002309 CHEBI:15343 ! has exposure stimulus acetaldehyde

[Term]
id: ECTO:9000960
name: exposure to acetamide
def: "An exposure to acetamide." []
synonym: "acetamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27856 ! has exposure stimulus acetamide
relationship: RO:0002309 CHEBI:27856 ! has exposure stimulus acetamide

[Term]
id: ECTO:9000961
name: exposure to acetonitrile
def: "An exposure to acetonitrile." []
synonym: "acetonitrile exposure" EXACT []
is_a: ECTO:9001621 ! exposure to volatile organic compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38472 ! has exposure stimulus acetonitrile
relationship: RO:0002309 CHEBI:38472 ! has exposure stimulus acetonitrile

[Term]
id: ECTO:9000962
name: exposure to acetophenone
def: "An exposure to acetophenone." []
synonym: "acetophenone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27632 ! has exposure stimulus acetophenone
relationship: RO:0002309 CHEBI:27632 ! has exposure stimulus acetophenone

[Term]
id: ECTO:9000963
name: exposure to 2-acetamidofluorene
def: "An exposure to 2-acetamidofluorene." []
synonym: "2-acetamidofluorene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17356 ! has exposure stimulus 2-acetamidofluorene
relationship: RO:0002309 CHEBI:17356 ! has exposure stimulus 2-acetamidofluorene

[Term]
id: ECTO:9000964
name: exposure to acrolein
def: "An exposure to acrolein." []
synonym: "acrolein exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15368 ! has exposure stimulus acrolein
relationship: RO:0002309 CHEBI:15368 ! has exposure stimulus acrolein

[Term]
id: ECTO:9000965
name: exposure to acrylic acid
def: "An exposure to acrylic acid." []
synonym: "acrylic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18308 ! has exposure stimulus acrylic acid
relationship: RO:0002309 CHEBI:18308 ! has exposure stimulus acrylic acid

[Term]
id: ECTO:9000966
name: exposure to acrylonitrile
def: "An exposure to acrylonitrile." []
synonym: "acrylonitrile exposure" EXACT []
is_a: ECTO:9001621 ! exposure to volatile organic compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28217 ! has exposure stimulus acrylonitrile
relationship: RO:0002309 CHEBI:28217 ! has exposure stimulus acrylonitrile

[Term]
id: ECTO:9000967
name: exposure to aldicarb
def: "An exposure to aldicarb." []
synonym: "aldicarb exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2555 ! has exposure stimulus aldicarb
relationship: RO:0002309 CHEBI:2555 ! has exposure stimulus aldicarb

[Term]
id: ECTO:9000968
name: exposure to (+)-trans-allethrin
def: "An exposure to (+)-trans-allethrin." []
synonym: "(+)-trans-allethrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39118 ! has exposure stimulus (+)-trans-allethrin
relationship: RO:0002309 CHEBI:39118 ! has exposure stimulus (+)-trans-allethrin

[Term]
id: ECTO:9000969
name: exposure to allyl alcohol
def: "An exposure to allyl alcohol." []
synonym: "allyl alcohol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16605 ! has exposure stimulus allyl alcohol
relationship: RO:0002309 CHEBI:16605 ! has exposure stimulus allyl alcohol

[Term]
id: ECTO:9000970
name: exposure to Allyl chloride
def: "An exposure to Allyl chloride." []
synonym: "Allyl chloride exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82379 ! has exposure stimulus Allyl chloride
relationship: RO:0002309 CHEBI:82379 ! has exposure stimulus Allyl chloride

[Term]
id: ECTO:9000971
name: exposure to aluminium metal
def: "An exposure to aluminium(0)." []
synonym: "aluminium(0) exposure" EXACT []
is_a: ECTO:9000029 ! exposure to aluminum
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33629 ! has exposure stimulus aluminium(0)
relationship: RO:0002309 CHEBI:33629 ! has exposure stimulus aluminium(0)

[Term]
id: ECTO:9000972
name: exposure to aluminium phosphide
def: "An exposure to aluminium phosphide." []
synonym: "aluminium phosphide exposure" EXACT []
is_a: ECTO:9000029 ! exposure to aluminum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38495 ! has exposure stimulus aluminium phosphide
relationship: RO:0002309 CHEBI:38495 ! has exposure stimulus aluminium phosphide

[Term]
id: ECTO:9000973
name: exposure to aluminium oxide
def: "An exposure to aluminium oxide." []
synonym: "aluminium oxide exposure" EXACT []
is_a: ECTO:9000030 ! exposure to aluminum oxides
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30187 ! has exposure stimulus aluminium oxide
relationship: RO:0002309 CHEBI:30187 ! has exposure stimulus aluminium oxide

[Term]
id: ECTO:9000974
name: exposure to 2-Aminoanthraquinone
def: "An exposure to 2-Aminoanthraquinone." []
synonym: "2-Aminoanthraquinone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34258 ! has exposure stimulus 2-Aminoanthraquinone
relationship: RO:0002309 CHEBI:34258 ! has exposure stimulus 2-Aminoanthraquinone

[Term]
id: ECTO:9000975
name: exposure to 4-(phenylazo)aniline
def: "An exposure to 4-(phenylazo)aniline." []
synonym: "4-(phenylazo)aniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233869 ! has exposure stimulus 4-(phenylazo)aniline
relationship: RO:0002309 CHEBI:233869 ! has exposure stimulus 4-(phenylazo)aniline

[Term]
id: ECTO:9000976
name: exposure to biphenyl-4-amine
def: "An exposure to biphenyl-4-amine." []
synonym: "biphenyl-4-amine exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:1784 ! has exposure stimulus biphenyl-4-amine
relationship: RO:0002309 CHEBI:1784 ! has exposure stimulus biphenyl-4-amine

[Term]
id: ECTO:9000977
name: exposure to 1-Amino-2-methylanthraquinone
def: "An exposure to 1-Amino-2-methylanthraquinone." []
synonym: "1-Amino-2-methylanthraquinone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82382 ! has exposure stimulus 1-Amino-2-methylanthraquinone
relationship: RO:0002309 CHEBI:82382 ! has exposure stimulus 1-Amino-2-methylanthraquinone

[Term]
id: ECTO:9000978
name: exposure to 1-Amino-2,4-dibromoanthraquinone
def: "An exposure to 1-Amino-2,4-dibromoanthraquinone." []
synonym: "1-Amino-2,4-dibromoanthraquinone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82304 ! has exposure stimulus 1-Amino-2,4-dibromoanthraquinone
relationship: RO:0002309 CHEBI:82304 ! has exposure stimulus 1-Amino-2,4-dibromoanthraquinone

[Term]
id: ECTO:9000979
name: exposure to anilazine
def: "An exposure to anilazine." []
synonym: "anilazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82076 ! has exposure stimulus anilazine
relationship: RO:0002309 CHEBI:82076 ! has exposure stimulus anilazine

[Term]
id: ECTO:9000980
name: exposure to aniline
def: "An exposure to aniline." []
synonym: "aniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17296 ! has exposure stimulus aniline
relationship: RO:0002309 CHEBI:17296 ! has exposure stimulus aniline

[Term]
id: ECTO:9000981
name: exposure to ortho-Anisidine
def: "An exposure to o-anisidine." []
synonym: "o-anisidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82288 ! has exposure stimulus o-anisidine
relationship: RO:0002309 CHEBI:82288 ! has exposure stimulus o-anisidine

[Term]
id: ECTO:9000982
name: exposure to anthracene
def: "An exposure to anthracene." []
synonym: "anthracene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35298 ! has exposure stimulus anthracene
relationship: RO:0002309 CHEBI:35298 ! has exposure stimulus anthracene

[Term]
id: ECTO:9000985
name: exposure to bendiocarb
def: "An exposure to bendiocarb." []
synonym: "bendiocarb exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34556 ! has exposure stimulus bendiocarb
relationship: RO:0002309 CHEBI:34556 ! has exposure stimulus bendiocarb

[Term]
id: ECTO:9000986
name: exposure to Benzal chloride
def: "An exposure to Benzal chloride." []
synonym: "Benzal chloride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82273 ! has exposure stimulus Benzal chloride
relationship: RO:0002309 CHEBI:82273 ! has exposure stimulus Benzal chloride

[Term]
id: ECTO:9000987
name: exposure to benzamide
def: "An exposure to benzamide." []
synonym: "benzamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28179 ! has exposure stimulus benzamide
relationship: RO:0002309 CHEBI:28179 ! has exposure stimulus benzamide

[Term]
id: ECTO:9000988
name: exposure to benzidine
def: "An exposure to benzidine." []
synonym: "benzidine exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80495 ! has exposure stimulus benzidine
relationship: RO:0002309 CHEBI:80495 ! has exposure stimulus benzidine

[Term]
id: ECTO:9000989
name: exposure to Benzotrichloride
def: "An exposure to (trichloromethyl)benzene." []
synonym: "(trichloromethyl)benzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82274 ! has exposure stimulus (trichloromethyl)benzene
relationship: RO:0002309 CHEBI:82274 ! has exposure stimulus (trichloromethyl)benzene

[Term]
id: ECTO:9000990
name: exposure to Benzoyl chloride
def: "An exposure to benzoyl chloride." []
synonym: "benzoyl chloride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82275 ! has exposure stimulus benzoyl chloride
relationship: RO:0002309 CHEBI:82275 ! has exposure stimulus benzoyl chloride

[Term]
id: ECTO:9000991
name: exposure to Benzoyl peroxide
def: "An exposure to Benzoyl peroxide." []
synonym: "Benzoyl peroxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82405 ! has exposure stimulus Benzoyl peroxide
relationship: RO:0002309 CHEBI:82405 ! has exposure stimulus Benzoyl peroxide

[Term]
id: ECTO:9000992
name: exposure to benzyl chloride
def: "An exposure to benzyl chloride." []
synonym: "benzyl chloride exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:615597 ! has exposure stimulus benzyl chloride
relationship: RO:0002309 CHEBI:615597 ! has exposure stimulus benzyl chloride

[Term]
id: ECTO:9000994
name: exposure to bifenthrin
def: "An exposure to bifenthrin." []
synonym: "bifenthrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3093 ! has exposure stimulus bifenthrin
relationship: RO:0002309 CHEBI:3093 ! has exposure stimulus bifenthrin

[Term]
id: ECTO:9000995
name: exposure to Bis(chloromethyl) ether
def: "An exposure to bis(chloromethyl) ether." []
synonym: "bis(chloromethyl) ether exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82270 ! has exposure stimulus bis(chloromethyl) ether
relationship: RO:0002309 CHEBI:82270 ! has exposure stimulus bis(chloromethyl) ether

[Term]
id: ECTO:9000996
name: exposure to Bis(2-chloro-1-methylethyl)ether
def: "An exposure to Bis(2-chloro-1-methylethyl)ether." []
synonym: "Bis(2-chloro-1-methylethyl)ether exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82409 ! has exposure stimulus Bis(2-chloro-1-methylethyl)ether
relationship: RO:0002309 CHEBI:82409 ! has exposure stimulus Bis(2-chloro-1-methylethyl)ether

[Term]
id: ECTO:9000997
name: exposure to tributylstannane
def: "An exposure to tributylstannane." []
synonym: "tributylstannane exposure" EXACT []
is_a: ECTO:9001388 ! exposure to organotin compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27086 ! has exposure stimulus tributylstannane
relationship: RO:0002309 CHEBI:27086 ! has exposure stimulus tributylstannane

[Term]
id: ECTO:9000998
name: exposure to boron trifluoride
def: "An exposure to boron trifluoride." []
synonym: "boron trifluoride exposure" EXACT []
is_a: ECTO:9000173 ! exposure to boron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33093 ! has exposure stimulus boron trifluoride
relationship: RO:0002309 CHEBI:33093 ! has exposure stimulus boron trifluoride

[Term]
id: ECTO:9000999
name: exposure to bromochlorodifluoromethane
def: "An exposure to bromochlorodifluoromethane." []
synonym: "bromochlorodifluoromethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84698 ! has exposure stimulus bromochlorodifluoromethane
relationship: RO:0002309 CHEBI:84698 ! has exposure stimulus bromochlorodifluoromethane

[Term]
id: ECTO:9001000
name: exposure to bromoform
def: "An exposure to bromoform." []
synonym: "bromoform exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38682 ! has exposure stimulus bromoform
relationship: RO:0002309 CHEBI:38682 ! has exposure stimulus bromoform

[Term]
id: ECTO:9001001
name: obsolete bromomethane exposure
is_obsolete: true
replaced_by: ECTO:9000098

[Term]
id: ECTO:9001002
name: exposure to Brucine
def: "An exposure to brucine." []
synonym: "brucine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3193 ! has exposure stimulus brucine
relationship: RO:0002309 CHEBI:3193 ! has exposure stimulus brucine

[Term]
id: ECTO:9001003
name: exposure to buta-1,3-diene
def: "An exposure to buta-1,3-diene." []
synonym: "buta-1,3-diene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39478 ! has exposure stimulus buta-1,3-diene
relationship: RO:0002309 CHEBI:39478 ! has exposure stimulus buta-1,3-diene

[Term]
id: ECTO:9001004
name: exposure to butyl acrylate
def: "An exposure to butyl acrylate." []
synonym: "butyl acrylate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3245 ! has exposure stimulus butyl acrylate
relationship: RO:0002309 CHEBI:3245 ! has exposure stimulus butyl acrylate

[Term]
id: ECTO:9001005
name: exposure to butan-2-ol
def: "An exposure to butan-2-ol." []
synonym: "butan-2-ol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35687 ! has exposure stimulus butan-2-ol
relationship: RO:0002309 CHEBI:35687 ! has exposure stimulus butan-2-ol

[Term]
id: ECTO:9001006
name: exposure to tert-butanol
def: "An exposure to tert-butanol." []
synonym: "tert-butanol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45895 ! has exposure stimulus tert-butanol
relationship: RO:0002309 CHEBI:45895 ! has exposure stimulus tert-butanol

[Term]
id: ECTO:9001007
name: exposure to butanal
def: "An exposure to butanal." []
synonym: "butanal exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15743 ! has exposure stimulus butanal
relationship: RO:0002309 CHEBI:15743 ! has exposure stimulus butanal

[Term]
id: ECTO:9001009
name: exposure to calcium cyanamide
def: "An exposure to calcium cyanamide." []
synonym: "calcium cyanamide exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64301 ! has exposure stimulus calcium cyanamide
relationship: RO:0002309 CHEBI:64301 ! has exposure stimulus calcium cyanamide

[Term]
id: ECTO:9001010
name: exposure to captan
def: "An exposure to captan." []
synonym: "captan exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34608 ! has exposure stimulus captan
relationship: RO:0002309 CHEBI:34608 ! has exposure stimulus captan

[Term]
id: ECTO:9001011
name: exposure to carbaryl
def: "An exposure to carbaryl." []
synonym: "carbaryl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3390 ! has exposure stimulus carbaryl
relationship: RO:0002309 CHEBI:3390 ! has exposure stimulus carbaryl

[Term]
id: ECTO:9001012
name: exposure to carbofuran
def: "An exposure to carbofuran." []
synonym: "carbofuran exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34611 ! has exposure stimulus carbofuran
relationship: RO:0002309 CHEBI:34611 ! has exposure stimulus carbofuran

[Term]
id: ECTO:9001013
name: exposure to carbon disulfide
def: "An exposure to carbon disulfide." []
synonym: "carbon disulfide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23012 ! has exposure stimulus carbon disulfide
relationship: RO:0002309 CHEBI:23012 ! has exposure stimulus carbon disulfide

[Term]
id: ECTO:9001014
name: exposure to carbonyl sulfide
def: "An exposure to carbonyl sulfide." []
synonym: "carbonyl sulfide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16573 ! has exposure stimulus carbonyl sulfide
relationship: RO:0002309 CHEBI:16573 ! has exposure stimulus carbonyl sulfide

[Term]
id: ECTO:9001015
name: exposure to carboxin
def: "An exposure to carboxin." []
synonym: "carboxin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3405 ! has exposure stimulus carboxin
relationship: RO:0002309 CHEBI:3405 ! has exposure stimulus carboxin

[Term]
id: ECTO:9001016
name: exposure to catechol
def: "An exposure to catechol." []
synonym: "catechol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18135 ! has exposure stimulus catechol
relationship: RO:0002309 CHEBI:18135 ! has exposure stimulus catechol

[Term]
id: ECTO:9001017
name: exposure to quinomethionate
def: "An exposure to quinomethionate." []
synonym: "quinomethionate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34620 ! has exposure stimulus quinomethionate
relationship: RO:0002309 CHEBI:34620 ! has exposure stimulus quinomethionate

[Term]
id: ECTO:9001018
name: exposure to Chloramben
def: "An exposure to Chloramben." []
synonym: "Chloramben exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82183 ! has exposure stimulus Chloramben
relationship: RO:0002309 CHEBI:82183 ! has exposure stimulus Chloramben

[Term]
id: ECTO:9001019
name: exposure to chlorendic acid
def: "An exposure to chlorendic acid." []
synonym: "chlorendic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76603 ! has exposure stimulus chlorendic acid
relationship: RO:0002309 CHEBI:76603 ! has exposure stimulus chlorendic acid

[Term]
id: ECTO:9001020
name: exposure to chlorimuron-ethyl
def: "An exposure to chlorimuron-ethyl." []
synonym: "chlorimuron-ethyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47319 ! has exposure stimulus chlorimuron-ethyl
relationship: RO:0002309 CHEBI:47319 ! has exposure stimulus chlorimuron-ethyl

[Term]
id: ECTO:9001021
name: obsolete exposure to chlorine atom
is_obsolete: true
replaced_by: ECTO:9000077

[Term]
id: ECTO:9001022
name: exposure to chlorine dioxide
def: "An exposure to chlorine dioxide." []
synonym: "chlorine dioxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52357 ! has exposure stimulus chlorine dioxide
relationship: RO:0002309 CHEBI:52357 ! has exposure stimulus chlorine dioxide

[Term]
id: ECTO:9001024
name: exposure to quaternium-15
def: "An exposure to quaternium-15." []
synonym: "quaternium-15 exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59607 ! has exposure stimulus quaternium-15
relationship: RO:0002309 CHEBI:59607 ! has exposure stimulus quaternium-15

[Term]
id: ECTO:9001025
name: exposure to 4-chloroaniline
def: "An exposure to 4-chloroaniline." []
synonym: "4-chloroaniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:20331 ! has exposure stimulus 4-chloroaniline
relationship: RO:0002309 CHEBI:20331 ! has exposure stimulus 4-chloroaniline

[Term]
id: ECTO:9001026
name: exposure to Chlorobenzilate
def: "An exposure to Chlorobenzilate." []
synonym: "Chlorobenzilate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34626 ! has exposure stimulus Chlorobenzilate
relationship: RO:0002309 CHEBI:34626 ! has exposure stimulus Chlorobenzilate

[Term]
id: ECTO:9001027
name: exposure to Chlorodifluoromethane
def: "An exposure to Chlorodifluoromethane." []
synonym: "Chlorodifluoromethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82417 ! has exposure stimulus Chlorodifluoromethane
relationship: RO:0002309 CHEBI:82417 ! has exposure stimulus Chlorodifluoromethane

[Term]
id: ECTO:9001030
name: exposure to chloromethane
def: "An exposure to chloromethane." []
synonym: "chloromethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36014 ! has exposure stimulus chloromethane
relationship: RO:0002309 CHEBI:36014 ! has exposure stimulus chloromethane

[Term]
id: ECTO:9001031
name: exposure to Chloromethyl methyl ether
def: "An exposure to Chloromethyl methyl ether." []
synonym: "Chloromethyl methyl ether exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82271 ! has exposure stimulus Chloromethyl methyl ether
relationship: RO:0002309 CHEBI:82271 ! has exposure stimulus Chloromethyl methyl ether

[Term]
id: ECTO:9001032
name: exposure to chloropicrin
def: "An exposure to chloropicrin." []
synonym: "chloropicrin exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39285 ! has exposure stimulus chloropicrin
relationship: RO:0002309 CHEBI:39285 ! has exposure stimulus chloropicrin

[Term]
id: ECTO:9001034
name: exposure to chlorothalonil
def: "An exposure to chlorothalonil." []
synonym: "chlorothalonil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3639 ! has exposure stimulus chlorothalonil
relationship: RO:0002309 CHEBI:3639 ! has exposure stimulus chlorothalonil

[Term]
id: ECTO:9001035
name: obsolete chromium molecular entity exposure
is_obsolete: true
replaced_by: ECTO:9000037

[Term]
id: ECTO:9001036
name: exposure to Guinea Green B
def: "An exposure to Guinea Green B." []
synonym: "Guinea Green B exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82471 ! has exposure stimulus Guinea Green B
relationship: RO:0002309 CHEBI:82471 ! has exposure stimulus Guinea Green B

[Term]
id: ECTO:9001037
name: exposure to Sudan II
def: "An exposure to Sudan II." []
synonym: "Sudan II exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82534 ! has exposure stimulus Sudan II
relationship: RO:0002309 CHEBI:82534 ! has exposure stimulus Sudan II

[Term]
id: ECTO:9001038
name: exposure to ortho-Aminoazotoluene
def: "An exposure to ortho-Aminoazotoluene." []
synonym: "ortho-Aminoazotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82285 ! has exposure stimulus ortho-Aminoazotoluene
relationship: RO:0002309 CHEBI:82285 ! has exposure stimulus ortho-Aminoazotoluene

[Term]
id: ECTO:9001039
name: exposure to Sudan I
def: "An exposure to Sudan I." []
synonym: "Sudan I exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30958 ! has exposure stimulus Sudan I
relationship: RO:0002309 CHEBI:30958 ! has exposure stimulus Sudan I

[Term]
id: ECTO:9001040
name: exposure to auramine O free base
def: "An exposure to auramine O free base." []
synonym: "auramine O free base exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51874 ! has exposure stimulus auramine O free base
relationship: RO:0002309 CHEBI:51874 ! has exposure stimulus auramine O free base

[Term]
id: ECTO:9001041
name: exposure to Vat Yellow 4
def: "An exposure to Vat Yellow 4." []
synonym: "Vat Yellow 4 exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82548 ! has exposure stimulus Vat Yellow 4
relationship: RO:0002309 CHEBI:82548 ! has exposure stimulus Vat Yellow 4

[Term]
id: ECTO:9001042
name: obsolete exposure to cobalt atom
is_obsolete: true
replaced_by: ECTO:9000943

[Term]
id: ECTO:9001043
name: exposure to para-Cresidine
def: "An exposure to para-Cresidine." []
synonym: "para-Cresidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82307 ! has exposure stimulus para-Cresidine
relationship: RO:0002309 CHEBI:82307 ! has exposure stimulus para-Cresidine

[Term]
id: ECTO:9001044
name: exposure to m-cresol
def: "An exposure to m-cresol." []
synonym: "m-cresol exposure" EXACT []
is_a: ECTO:9001047 ! exposure to cresol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17231 ! has exposure stimulus m-cresol
relationship: RO:0002309 CHEBI:17231 ! has exposure stimulus m-cresol

[Term]
id: ECTO:9001045
name: exposure to o-cresol
def: "An exposure to o-cresol." []
synonym: "o-cresol exposure" EXACT []
is_a: ECTO:9001047 ! exposure to cresol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28054 ! has exposure stimulus o-cresol
relationship: RO:0002309 CHEBI:28054 ! has exposure stimulus o-cresol

[Term]
id: ECTO:9001046
name: exposure to p-cresol
def: "An exposure to p-cresol." []
synonym: "p-cresol exposure" EXACT []
is_a: ECTO:9001047 ! exposure to cresol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17847 ! has exposure stimulus p-cresol
relationship: RO:0002309 CHEBI:17847 ! has exposure stimulus p-cresol

[Term]
id: ECTO:9001047
name: exposure to cresol
def: "An exposure to cresol." []
synonym: "cresol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25399 ! has exposure stimulus cresol
relationship: RO:0002309 CHEBI:25399 ! has exposure stimulus cresol

[Term]
id: ECTO:9001048
name: exposure to crotonaldehyde
def: "An exposure to crotonaldehyde." []
synonym: "crotonaldehyde exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41607 ! has exposure stimulus crotonaldehyde
relationship: RO:0002309 CHEBI:41607 ! has exposure stimulus crotonaldehyde

[Term]
id: ECTO:9001049
name: exposure to Cycloate
def: "An exposure to Cycloate." []
synonym: "Cycloate exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81955 ! has exposure stimulus Cycloate
relationship: RO:0002309 CHEBI:81955 ! has exposure stimulus Cycloate

[Term]
id: ECTO:9001050
name: exposure to cyclohexane
def: "An exposure to cyclohexane." []
synonym: "cyclohexane exposure" EXACT []
is_a: ECTO:9000199 ! exposure to cycloalkane
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29005 ! has exposure stimulus cyclohexane
relationship: RO:0002309 CHEBI:29005 ! has exposure stimulus cyclohexane

[Term]
id: ECTO:9001051
name: exposure to cyclohexanol
def: "An exposure to cyclohexanol." []
synonym: "cyclohexanol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18099 ! has exposure stimulus cyclohexanol
relationship: RO:0002309 CHEBI:18099 ! has exposure stimulus cyclohexanol

[Term]
id: ECTO:9001052
name: obsolete cyfluthrin exposure
is_obsolete: true
replaced_by: ECTO:9000122

[Term]
id: ECTO:9001053
name: exposure to cyhalothrin
def: "An exposure to cyhalothrin." []
synonym: "cyhalothrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4035 ! has exposure stimulus cyhalothrin
relationship: RO:0002309 CHEBI:4035 ! has exposure stimulus cyhalothrin

[Term]
id: ECTO:9001054
name: exposure to (2,4-dichlorophenoxy)acetate
def: "An exposure to (2,4-dichlorophenoxy)acetate." []
synonym: "(2,4-dichlorophenoxy)acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:19351 ! has exposure stimulus (2,4-dichlorophenoxy)acetate
relationship: RO:0002309 CHEBI:19351 ! has exposure stimulus (2,4-dichlorophenoxy)acetate

[Term]
id: ECTO:9001055
name: exposure to dazomet
def: "An exposure to dazomet." []
synonym: "dazomet exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75212 ! has exposure stimulus dazomet
relationship: RO:0002309 CHEBI:75212 ! has exposure stimulus dazomet

[Term]
id: ECTO:9001056
name: exposure to 2,4-DB
def: "An exposure to 2,4-DB." []
synonym: "2,4-DB exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73173 ! has exposure stimulus 2,4-DB
relationship: RO:0002309 CHEBI:73173 ! has exposure stimulus 2,4-DB

[Term]
id: ECTO:9001057
name: exposure to decabromodiphenyl ether
def: "An exposure to decabromodiphenyl ether." []
synonym: "decabromodiphenyl ether exposure" EXACT []
is_a: ECTO:9001619 ! exposure to polybromodiphenyl ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82436 ! has exposure stimulus decabromodiphenyl ether
relationship: RO:0002309 CHEBI:82436 ! has exposure stimulus decabromodiphenyl ether

[Term]
id: ECTO:9001058
name: exposure to 2,4-Diaminoanisole
def: "An exposure to 2,4-Diaminoanisole." []
synonym: "2,4-Diaminoanisole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82309 ! has exposure stimulus 2,4-Diaminoanisole
relationship: RO:0002309 CHEBI:82309 ! has exposure stimulus 2,4-Diaminoanisole

[Term]
id: ECTO:9001059
name: exposure to 2,4-diaminotoluene
def: "An exposure to 2,4-diaminotoluene." []
synonym: "2,4-diaminotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34237 ! has exposure stimulus 2,4-diaminotoluene
relationship: RO:0002309 CHEBI:34237 ! has exposure stimulus 2,4-diaminotoluene

[Term]
id: ECTO:9001060
name: exposure to diazomethane
def: "An exposure to diazomethane." []
synonym: "diazomethane exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73716 ! has exposure stimulus diazomethane
relationship: RO:0002309 CHEBI:73716 ! has exposure stimulus diazomethane

[Term]
id: ECTO:9001061
name: exposure to dibenzofuran
def: "An exposure to dibenzofuran." []
synonym: "dibenzofuran exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28145 ! has exposure stimulus dibenzofuran
relationship: RO:0002309 CHEBI:28145 ! has exposure stimulus dibenzofuran

[Term]
id: ECTO:9001063
name: exposure to 2,6-dichloro-4-nitroaniline
def: "An exposure to 2,6-dichloro-4-nitroaniline." []
synonym: "2,6-dichloro-4-nitroaniline exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27864 ! has exposure stimulus 2,6-dichloro-4-nitroaniline
relationship: RO:0002309 CHEBI:27864 ! has exposure stimulus 2,6-dichloro-4-nitroaniline

[Term]
id: ECTO:9001064
name: exposure to 1,3-dichlorobenzene
def: "An exposure to 1,3-dichlorobenzene." []
synonym: "1,3-dichlorobenzene exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36693 ! has exposure stimulus 1,3-dichlorobenzene
relationship: RO:0002309 CHEBI:36693 ! has exposure stimulus 1,3-dichlorobenzene

[Term]
id: ECTO:9001065
name: exposure to 1,4-dichlorobenzene
def: "An exposure to 1,4-dichlorobenzene." []
synonym: "1,4-dichlorobenzene exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28618 ! has exposure stimulus 1,4-dichlorobenzene
relationship: RO:0002309 CHEBI:28618 ! has exposure stimulus 1,4-dichlorobenzene

[Term]
id: ECTO:9001067
name: exposure to 3,3'-Dichlorobenzidine
def: "An exposure to 3,3'-Dichlorobenzidine." []
synonym: "3,3'-Dichlorobenzidine exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000056 ! exposure to biphenyls
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82315 ! has exposure stimulus 3,3'-Dichlorobenzidine
relationship: RO:0002309 CHEBI:82315 ! has exposure stimulus 3,3'-Dichlorobenzidine

[Term]
id: ECTO:9001068
name: exposure to trans-1,4-Dichlorobutene
def: "An exposure to trans-1,4-Dichlorobutene." []
synonym: "trans-1,4-Dichlorobutene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82446 ! has exposure stimulus trans-1,4-Dichlorobutene
relationship: RO:0002309 CHEBI:82446 ! has exposure stimulus trans-1,4-Dichlorobutene

[Term]
id: ECTO:9001069
name: exposure to 1,2-dichloroethene
def: "An exposure to 1,2-dichloroethene." []
synonym: "1,2-dichloroethene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18882 ! has exposure stimulus 1,2-dichloroethene
relationship: RO:0002309 CHEBI:18882 ! has exposure stimulus 1,2-dichloroethene

[Term]
id: ECTO:9001070
name: exposure to 4-chlorophenol
def: "An exposure to 4-chlorophenol." []
synonym: "4-chlorophenol exposure" EXACT []
is_a: ECTO:9001308 ! exposure to chlorophenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28078 ! has exposure stimulus 4-chlorophenol
relationship: RO:0002309 CHEBI:28078 ! has exposure stimulus 4-chlorophenol

[Term]
id: ECTO:9001071
name: exposure to 2,4-dichlorophenol
def: "An exposure to 2,4-dichlorophenol." []
synonym: "2,4-dichlorophenol exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9001308 ! exposure to chlorophenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16738 ! has exposure stimulus 2,4-dichlorophenol
relationship: RO:0002309 CHEBI:16738 ! has exposure stimulus 2,4-dichlorophenol

[Term]
id: ECTO:9001072
name: exposure to (E)-1,3-dichloropropene
def: "An exposure to (E)-1,3-dichloropropene." []
synonym: "(E)-1,3-dichloropropene exposure" EXACT []
is_a: ECTO:9001527 ! exposure to 1,3-dichloropropene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18624 ! has exposure stimulus (E)-1,3-dichloropropene
relationship: RO:0002309 CHEBI:18624 ! has exposure stimulus (E)-1,3-dichloropropene

[Term]
id: ECTO:9001073
name: exposure to dichlorvos
def: "An exposure to dichlorvos." []
synonym: "dichlorvos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34690 ! has exposure stimulus dichlorvos
relationship: RO:0002309 CHEBI:34690 ! has exposure stimulus dichlorvos

[Term]
id: ECTO:9001074
name: exposure to Diclofop methyl
def: "An exposure to diclofop-methyl." []
synonym: "diclofop-methyl exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4510 ! has exposure stimulus diclofop-methyl
relationship: RO:0002309 CHEBI:4510 ! has exposure stimulus diclofop-methyl

[Term]
id: ECTO:9001075
name: exposure to dicofol
def: "An exposure to dicofol." []
synonym: "dicofol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34692 ! has exposure stimulus dicofol
relationship: RO:0002309 CHEBI:34692 ! has exposure stimulus dicofol

[Term]
id: ECTO:9001076
name: exposure to Dicyclopentadiene
def: "An exposure to Dicyclopentadiene." []
synonym: "Dicyclopentadiene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34695 ! has exposure stimulus Dicyclopentadiene
relationship: RO:0002309 CHEBI:34695 ! has exposure stimulus Dicyclopentadiene

[Term]
id: ECTO:9001077
name: exposure to diepoxybutane
def: "An exposure to diepoxybutane." []
synonym: "diepoxybutane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23704 ! has exposure stimulus diepoxybutane
relationship: RO:0002309 CHEBI:23704 ! has exposure stimulus diepoxybutane

[Term]
id: ECTO:9001078
name: exposure to diethanolamine
def: "An exposure to diethanolamine." []
synonym: "diethanolamine exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28123 ! has exposure stimulus diethanolamine
relationship: RO:0002309 CHEBI:28123 ! has exposure stimulus diethanolamine

[Term]
id: ECTO:9001079
name: exposure to diethyl sulfate
def: "An exposure to diethyl sulfate." []
synonym: "diethyl sulfate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34699 ! has exposure stimulus diethyl sulfate
relationship: RO:0002309 CHEBI:34699 ! has exposure stimulus diethyl sulfate

[Term]
id: ECTO:9001080
name: exposure to diflubenzuron
def: "An exposure to diflubenzuron." []
synonym: "diflubenzuron exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34703 ! has exposure stimulus diflubenzuron
relationship: RO:0002309 CHEBI:34703 ! has exposure stimulus diflubenzuron

[Term]
id: ECTO:9001081
name: exposure to Diglycidyl resorcinol ether
def: "An exposure to Diglycidyl resorcinol ether." []
synonym: "Diglycidyl resorcinol ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82318 ! has exposure stimulus Diglycidyl resorcinol ether
relationship: RO:0002309 CHEBI:82318 ! has exposure stimulus Diglycidyl resorcinol ether

[Term]
id: ECTO:9001082
name: exposure to Dihydrosafrole
def: "An exposure to Dihydrosafrole." []
synonym: "Dihydrosafrole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82319 ! has exposure stimulus Dihydrosafrole
relationship: RO:0002309 CHEBI:82319 ! has exposure stimulus Dihydrosafrole

[Term]
id: ECTO:9001083
name: exposure to Dimethipin
def: "An exposure to Dimethipin." []
synonym: "Dimethipin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81912 ! has exposure stimulus Dimethipin
relationship: RO:0002309 CHEBI:81912 ! has exposure stimulus Dimethipin

[Term]
id: ECTO:9001084
name: exposure to 3,3'-Dimethoxybenzidine
def: "An exposure to 3,3'-Dimethoxybenzidine." []
synonym: "3,3'-Dimethoxybenzidine exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82321 ! has exposure stimulus 3,3'-Dimethoxybenzidine
relationship: RO:0002309 CHEBI:82321 ! has exposure stimulus 3,3'-Dimethoxybenzidine

[Term]
id: ECTO:9001085
name: exposure to dimethylamine
def: "An exposure to dimethylamine." []
synonym: "dimethylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17170 ! has exposure stimulus dimethylamine
relationship: RO:0002309 CHEBI:17170 ! has exposure stimulus dimethylamine

[Term]
id: ECTO:9001086
name: exposure to N,N-dimethylaniline
def: "An exposure to N,N-dimethylaniline." []
synonym: "N,N-dimethylaniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16269 ! has exposure stimulus N,N-dimethylaniline
relationship: RO:0002309 CHEBI:16269 ! has exposure stimulus N,N-dimethylaniline

[Term]
id: ECTO:9001087
name: exposure to 3,3'-Dimethylbenzidine
def: "An exposure to 3,3'-Dimethylbenzidine." []
synonym: "3,3'-Dimethylbenzidine exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34320 ! has exposure stimulus 3,3'-Dimethylbenzidine
relationship: RO:0002309 CHEBI:34320 ! has exposure stimulus 3,3'-Dimethylbenzidine

[Term]
id: ECTO:9001088
name: exposure to N,N-dimethylformamide
def: "An exposure to N,N-dimethylformamide." []
synonym: "N,N-dimethylformamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17741 ! has exposure stimulus N,N-dimethylformamide
relationship: RO:0002309 CHEBI:17741 ! has exposure stimulus N,N-dimethylformamide

[Term]
id: ECTO:9001089
name: exposure to 2,4-Dimethylphenol
def: "An exposure to 2,4-xylenol." []
synonym: "2,4-xylenol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34241 ! has exposure stimulus 2,4-xylenol
relationship: RO:0002309 CHEBI:34241 ! has exposure stimulus 2,4-xylenol

[Term]
id: ECTO:9001090
name: exposure to Dimethyl phthalate
def: "An exposure to Dimethyl phthalate." []
synonym: "Dimethyl phthalate exposure" EXACT []
is_a: ECTO:9000906 ! exposure to phthalate ester
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4609 ! has exposure stimulus Dimethyl phthalate
relationship: RO:0002309 CHEBI:4609 ! has exposure stimulus Dimethyl phthalate

[Term]
id: ECTO:9001091
name: exposure to dimethyl sulfate
def: "An exposure to dimethyl sulfate." []
synonym: "dimethyl sulfate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59050 ! has exposure stimulus dimethyl sulfate
relationship: RO:0002309 CHEBI:59050 ! has exposure stimulus dimethyl sulfate

[Term]
id: ECTO:9001092
name: exposure to 1,3-dinitrobenzene
def: "An exposure to 1,3-dinitrobenzene." []
synonym: "1,3-dinitrobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51397 ! has exposure stimulus 1,3-dinitrobenzene
relationship: RO:0002309 CHEBI:51397 ! has exposure stimulus 1,3-dinitrobenzene

[Term]
id: ECTO:9001093
name: exposure to 1,2-dinitrobenzene
def: "An exposure to 1,2-dinitrobenzene." []
synonym: "1,2-dinitrobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34053 ! has exposure stimulus 1,2-dinitrobenzene
relationship: RO:0002309 CHEBI:34053 ! has exposure stimulus 1,2-dinitrobenzene

[Term]
id: ECTO:9001094
name: exposure to 1,4-dinitrobenzene
def: "An exposure to 1,4-dinitrobenzene." []
synonym: "1,4-dinitrobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51398 ! has exposure stimulus 1,4-dinitrobenzene
relationship: RO:0002309 CHEBI:51398 ! has exposure stimulus 1,4-dinitrobenzene

[Term]
id: ECTO:9001095
name: exposure to 4,6-dinitro-o-cresol
def: "An exposure to 4,6-dinitro-o-cresol." []
synonym: "4,6-dinitro-o-cresol exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39349 ! has exposure stimulus 4,6-dinitro-o-cresol
relationship: RO:0002309 CHEBI:39349 ! has exposure stimulus 4,6-dinitro-o-cresol

[Term]
id: ECTO:9001096
name: exposure to 2,4-dinitrophenol
def: "An exposure to 2,4-dinitrophenol." []
synonym: "2,4-dinitrophenol exposure" EXACT []
is_a: ECTO:9000499 ! exposure to dinitrophenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42017 ! has exposure stimulus 2,4-dinitrophenol
relationship: RO:0002309 CHEBI:42017 ! has exposure stimulus 2,4-dinitrophenol

[Term]
id: ECTO:9001097
name: exposure to 2,4-dinitrotoluene
def: "An exposure to 2,4-dinitrotoluene." []
synonym: "2,4-dinitrotoluene exposure" EXACT []
is_a: ECTO:9001099 ! exposure to dinitrotoluene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:920 ! has exposure stimulus 2,4-dinitrotoluene
relationship: RO:0002309 CHEBI:920 ! has exposure stimulus 2,4-dinitrotoluene

[Term]
id: ECTO:9001098
name: exposure to 2,6-dinitrotoluene
def: "An exposure to 2,6-dinitrotoluene." []
synonym: "2,6-dinitrotoluene exposure" EXACT []
is_a: ECTO:9001099 ! exposure to dinitrotoluene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:957 ! has exposure stimulus 2,6-dinitrotoluene
relationship: RO:0002309 CHEBI:957 ! has exposure stimulus 2,6-dinitrotoluene

[Term]
id: ECTO:9001099
name: exposure to dinitrotoluene
def: "An exposure to dinitrotoluene." []
synonym: "dinitrotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23822 ! has exposure stimulus dinitrotoluene
relationship: RO:0002309 CHEBI:23822 ! has exposure stimulus dinitrotoluene

[Term]
id: ECTO:9001100
name: exposure to dinocap
def: "An exposure to dinocap." []
synonym: "dinocap exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83379 ! has exposure stimulus dinocap
relationship: RO:0002309 CHEBI:83379 ! has exposure stimulus dinocap

[Term]
id: ECTO:9001101
name: exposure to 1,4-dioxane
def: "An exposure to 1,4-dioxane." []
synonym: "1,4-dioxane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47032 ! has exposure stimulus 1,4-dioxane
relationship: RO:0002309 CHEBI:47032 ! has exposure stimulus 1,4-dioxane

[Term]
id: ECTO:9001102
name: exposure to Diphenamid
def: "An exposure to Diphenamid." []
synonym: "Diphenamid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81915 ! has exposure stimulus Diphenamid
relationship: RO:0002309 CHEBI:81915 ! has exposure stimulus Diphenamid

[Term]
id: ECTO:9001103
name: exposure to diphenylamine
def: "An exposure to diphenylamine." []
synonym: "diphenylamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4640 ! has exposure stimulus diphenylamine
relationship: RO:0002309 CHEBI:4640 ! has exposure stimulus diphenylamine

[Term]
id: ECTO:9001104
name: exposure to phenylhydrazine
def: "An exposure to phenylhydrazine." []
synonym: "phenylhydrazine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27924 ! has exposure stimulus phenylhydrazine
relationship: RO:0002309 CHEBI:27924 ! has exposure stimulus phenylhydrazine

[Term]
id: ECTO:9001105
name: exposure to 1-dodecylguanidine
def: "An exposure to 1-dodecylguanidine." []
synonym: "1-dodecylguanidine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74880 ! has exposure stimulus 1-dodecylguanidine
relationship: RO:0002309 CHEBI:74880 ! has exposure stimulus 1-dodecylguanidine

[Term]
id: ECTO:9001106
name: obsolete epichlorohydrin exposure
is_obsolete: true
replaced_by: ECTO:9000114

[Term]
id: ECTO:9001107
name: exposure to ethoprophos
def: "An exposure to ethoprophos." []
synonym: "ethoprophos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38665 ! has exposure stimulus ethoprophos
relationship: RO:0002309 CHEBI:38665 ! has exposure stimulus ethoprophos

[Term]
id: ECTO:9001109
name: exposure to Ethyl acrylate
def: "An exposure to Ethyl acrylate." []
synonym: "Ethyl acrylate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82327 ! has exposure stimulus Ethyl acrylate
relationship: RO:0002309 CHEBI:82327 ! has exposure stimulus Ethyl acrylate

[Term]
id: ECTO:9001110
name: exposure to EPTC
def: "An exposure to EPTC." []
synonym: "EPTC exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4738 ! has exposure stimulus EPTC
relationship: RO:0002309 CHEBI:4738 ! has exposure stimulus EPTC

[Term]
id: ECTO:9001111
name: exposure to ethylene glycol
def: "An exposure to ethylene glycol." []
synonym: "ethylene glycol exposure" EXACT []
is_a: ECTO:9002156 ! exposure to glycol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30742 ! has exposure stimulus ethylene glycol
relationship: RO:0002309 CHEBI:30742 ! has exposure stimulus ethylene glycol

[Term]
id: ECTO:9001112
name: exposure to aziridine
def: "An exposure to aziridine." []
synonym: "aziridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30969 ! has exposure stimulus aziridine
relationship: RO:0002309 CHEBI:30969 ! has exposure stimulus aziridine

[Term]
id: ECTO:9001113
name: exposure to oxirane
def: "An exposure to oxirane." []
synonym: "oxirane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27561 ! has exposure stimulus oxirane
relationship: RO:0002309 CHEBI:27561 ! has exposure stimulus oxirane

[Term]
id: ECTO:9001114
name: exposure to famphur
def: "An exposure to famphur." []
synonym: "famphur exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38677 ! has exposure stimulus famphur
relationship: RO:0002309 CHEBI:38677 ! has exposure stimulus famphur

[Term]
id: ECTO:9001115
name: exposure to fenarimol
def: "An exposure to fenarimol." []
synonym: "fenarimol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4998 ! has exposure stimulus fenarimol
relationship: RO:0002309 CHEBI:4998 ! has exposure stimulus fenarimol

[Term]
id: ECTO:9001116
name: exposure to fenbutatin oxide
def: "An exposure to fenbutatin oxide." []
synonym: "fenbutatin oxide exposure" EXACT []
is_a: ECTO:9001389 ! exposure to organotin acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39294 ! has exposure stimulus fenbutatin oxide
relationship: RO:0002309 CHEBI:39294 ! has exposure stimulus fenbutatin oxide

[Term]
id: ECTO:9001117
name: exposure to Fenoxaprop ethyl
def: "An exposure to Fenoxaprop ethyl." []
synonym: "Fenoxaprop ethyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5008 ! has exposure stimulus Fenoxaprop ethyl
relationship: RO:0002309 CHEBI:5008 ! has exposure stimulus Fenoxaprop ethyl

[Term]
id: ECTO:9001118
name: exposure to fenpropathrin
def: "An exposure to fenpropathrin." []
synonym: "fenpropathrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39353 ! has exposure stimulus fenpropathrin
relationship: RO:0002309 CHEBI:39353 ! has exposure stimulus fenpropathrin

[Term]
id: ECTO:9001119
name: exposure to fenthion
def: "An exposure to fenthion." []
synonym: "fenthion exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34761 ! has exposure stimulus fenthion
relationship: RO:0002309 CHEBI:34761 ! has exposure stimulus fenthion

[Term]
id: ECTO:9001120
name: exposure to fenvalerate
def: "An exposure to fenvalerate." []
synonym: "fenvalerate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5014 ! has exposure stimulus fenvalerate
relationship: RO:0002309 CHEBI:5014 ! has exposure stimulus fenvalerate

[Term]
id: ECTO:9001121
name: exposure to ferbam
def: "An exposure to ferbam." []
synonym: "ferbam exposure" EXACT []
is_a: ECTO:9000087 ! exposure to iron
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5015 ! has exposure stimulus ferbam
relationship: RO:0002309 CHEBI:5015 ! has exposure stimulus ferbam

[Term]
id: ECTO:9001122
name: exposure to Fluazifop butyl
def: "An exposure to fluazifop-butyl." []
synonym: "fluazifop-butyl exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5097 ! has exposure stimulus fluazifop-butyl
relationship: RO:0002309 CHEBI:5097 ! has exposure stimulus fluazifop-butyl

[Term]
id: ECTO:9001123
name: exposure to Fluometuron
def: "An exposure to fluometuron." []
synonym: "fluometuron exposure" EXACT []
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82012 ! has exposure stimulus fluometuron
relationship: RO:0002309 CHEBI:82012 ! has exposure stimulus fluometuron

[Term]
id: ECTO:9001124
name: exposure to fluorine
def: "An exposure to fluorine molecular entity." []
synonym: "fluorine molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24062 ! has exposure stimulus fluorine molecular entity
relationship: RO:0002309 CHEBI:24062 ! has exposure stimulus fluorine molecular entity

[Term]
id: ECTO:9001125
name: exposure to fluvalinate
def: "An exposure to fluvalinate." []
synonym: "fluvalinate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5135 ! has exposure stimulus fluvalinate
relationship: RO:0002309 CHEBI:5135 ! has exposure stimulus fluvalinate

[Term]
id: ECTO:9001126
name: exposure to folpet
def: "An exposure to folpet." []
synonym: "folpet exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82019 ! has exposure stimulus folpet
relationship: RO:0002309 CHEBI:82019 ! has exposure stimulus folpet

[Term]
id: ECTO:9001127
name: exposure to Fomesafen
def: "An exposure to fomesafen." []
synonym: "fomesafen exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81925 ! has exposure stimulus fomesafen
relationship: RO:0002309 CHEBI:81925 ! has exposure stimulus fomesafen

[Term]
id: ECTO:9001128
name: exposure to furan
def: "An exposure to furan." []
synonym: "furan exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35559 ! has exposure stimulus furan
relationship: RO:0002309 CHEBI:35559 ! has exposure stimulus furan

[Term]
id: ECTO:9001129
name: exposure to glycidol
def: "An exposure to glycidol." []
synonym: "glycidol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30966 ! has exposure stimulus glycidol
relationship: RO:0002309 CHEBI:30966 ! has exposure stimulus glycidol

[Term]
id: ECTO:9001130
name: exposure to Hexachloro-1,3-butadiene
def: "An exposure to Hexachloro-1,3-butadiene." []
synonym: "Hexachloro-1,3-butadiene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5691 ! has exposure stimulus Hexachloro-1,3-butadiene
relationship: RO:0002309 CHEBI:5691 ! has exposure stimulus Hexachloro-1,3-butadiene

[Term]
id: ECTO:9001131
name: exposure to hexachlorophene
def: "An exposure to hexachlorophene." []
synonym: "hexachlorophene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5693 ! has exposure stimulus hexachlorophene
relationship: RO:0002309 CHEBI:5693 ! has exposure stimulus hexachlorophene

[Term]
id: ECTO:9001132
name: exposure to hexamethylphosphoric triamide
def: "An exposure to hexamethylphosphoric triamide." []
synonym: "hexamethylphosphoric triamide exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24565 ! has exposure stimulus hexamethylphosphoric triamide
relationship: RO:0002309 CHEBI:24565 ! has exposure stimulus hexamethylphosphoric triamide

[Term]
id: ECTO:9001133
name: exposure to Hexazinone
def: "An exposure to Hexazinone." []
synonym: "Hexazinone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5705 ! has exposure stimulus Hexazinone
relationship: RO:0002309 CHEBI:5705 ! has exposure stimulus Hexazinone

[Term]
id: ECTO:9001134
name: exposure to hydramethylnon
def: "An exposure to hydramethylnon." []
synonym: "hydramethylnon exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2630 ! has exposure stimulus hydramethylnon
relationship: RO:0002309 CHEBI:2630 ! has exposure stimulus hydramethylnon

[Term]
id: ECTO:9001135
name: exposure to hydrazine
def: "An exposure to hydrazine." []
synonym: "hydrazine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15571 ! has exposure stimulus hydrazine
relationship: RO:0002309 CHEBI:15571 ! has exposure stimulus hydrazine

[Term]
id: ECTO:9001137
name: exposure to hydrogen cyanide
def: "An exposure to hydrogen cyanide." []
synonym: "hydrogen cyanide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18407 ! has exposure stimulus hydrogen cyanide
relationship: RO:0002309 CHEBI:18407 ! has exposure stimulus hydrogen cyanide

[Term]
id: ECTO:9001138
name: exposure to hydrogen fluoride
def: "An exposure to hydrogen fluoride." []
synonym: "hydrogen fluoride exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29228 ! has exposure stimulus hydrogen fluoride
relationship: RO:0002309 CHEBI:29228 ! has exposure stimulus hydrogen fluoride

[Term]
id: ECTO:9001139
name: exposure to hydroquinone
def: "An exposure to hydroquinone." []
synonym: "hydroquinone exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17594 ! has exposure stimulus hydroquinone
relationship: RO:0002309 CHEBI:17594 ! has exposure stimulus hydroquinone

[Term]
id: ECTO:9001140
name: exposure to enilconazole
def: "An exposure to enilconazole." []
synonym: "enilconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81927 ! has exposure stimulus enilconazole
relationship: RO:0002309 CHEBI:81927 ! has exposure stimulus enilconazole

[Term]
id: ECTO:9001141
name: exposure to pentacarbonyliron
def: "An exposure to pentacarbonyliron." []
synonym: "pentacarbonyliron exposure" EXACT []
is_a: ECTO:9000087 ! exposure to iron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30251 ! has exposure stimulus pentacarbonyliron
relationship: RO:0002309 CHEBI:30251 ! has exposure stimulus pentacarbonyliron

[Term]
id: ECTO:9001142
name: exposure to isobutyraldehyde
def: "An exposure to isobutyraldehyde." []
synonym: "isobutyraldehyde exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48943 ! has exposure stimulus isobutyraldehyde
relationship: RO:0002309 CHEBI:48943 ! has exposure stimulus isobutyraldehyde

[Term]
id: ECTO:9001143
name: exposure to Isodrin
def: "An exposure to Isodrin." []
synonym: "Isodrin exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82100 ! has exposure stimulus Isodrin
relationship: RO:0002309 CHEBI:82100 ! has exposure stimulus Isodrin

[Term]
id: ECTO:9001144
name: exposure to isoprene
def: "An exposure to isoprene." []
synonym: "isoprene exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35194 ! has exposure stimulus isoprene
relationship: RO:0002309 CHEBI:35194 ! has exposure stimulus isoprene

[Term]
id: ECTO:9001145
name: obsolete propan-2-ol exposure
is_obsolete: true
replaced_by: ECTO:9000099

[Term]
id: ECTO:9001146
name: exposure to Isosafrole
def: "An exposure to Isosafrole." []
synonym: "Isosafrole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6054 ! has exposure stimulus Isosafrole
relationship: RO:0002309 CHEBI:6054 ! has exposure stimulus Isosafrole

[Term]
id: ECTO:9001147
name: exposure to trifluoromethyl group
def: "An exposure to trifluoromethyl group." []
synonym: "trifluoromethyl group exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50127 ! has exposure stimulus trifluoromethyl group
relationship: RO:0002309 CHEBI:50127 ! has exposure stimulus trifluoromethyl group

[Term]
id: ECTO:9001149
name: exposure to lithium carbonate
def: "An exposure to lithium carbonate." []
synonym: "lithium carbonate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6504 ! has exposure stimulus lithium carbonate
relationship: RO:0002309 CHEBI:6504 ! has exposure stimulus lithium carbonate

[Term]
id: ECTO:9001150
name: exposure to malathion
def: "An exposure to malathion." []
synonym: "malathion exposure" EXACT []
is_a: ECTO:9000284 ! exposure to organophosphorus compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6651 ! has exposure stimulus malathion
relationship: RO:0002309 CHEBI:6651 ! has exposure stimulus malathion

[Term]
id: ECTO:9001151
name: exposure to maleic anhydride
def: "An exposure to maleic anhydride." []
synonym: "maleic anhydride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:474859 ! has exposure stimulus maleic anhydride
relationship: RO:0002309 CHEBI:474859 ! has exposure stimulus maleic anhydride

[Term]
id: ECTO:9001152
name: exposure to malononitrile
def: "An exposure to malononitrile." []
synonym: "malononitrile exposure" EXACT []
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33186 ! has exposure stimulus malononitrile
relationship: RO:0002309 CHEBI:33186 ! has exposure stimulus malononitrile

[Term]
id: ECTO:9001153
name: exposure to maneb
def: "An exposure to maneb." []
synonym: "maneb exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52497 ! has exposure stimulus maneb
relationship: RO:0002309 CHEBI:52497 ! has exposure stimulus maneb

[Term]
id: ECTO:9001154
name: exposure to elemental manganese
def: "An exposure to elemental manganese." []
synonym: "elemental manganese exposure" EXACT []
is_a: ECTO:9000946 ! exposure to manganese
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35115 ! has exposure stimulus elemental manganese
relationship: RO:0002309 CHEBI:35115 ! has exposure stimulus elemental manganese

[Term]
id: ECTO:9001155
name: exposure to 1,3-benzothiazole-2-thiol
def: "An exposure to 1,3-benzothiazole-2-thiol." []
synonym: "1,3-benzothiazole-2-thiol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34292 ! has exposure stimulus 1,3-benzothiazole-2-thiol
relationship: RO:0002309 CHEBI:34292 ! has exposure stimulus 1,3-benzothiazole-2-thiol

[Term]
id: ECTO:9001156
name: exposure to Methazole
def: "An exposure to Methazole." []
synonym: "Methazole exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82244 ! has exposure stimulus Methazole
relationship: RO:0002309 CHEBI:82244 ! has exposure stimulus Methazole

[Term]
id: ECTO:9001157
name: exposure to methoxychlor
def: "An exposure to methoxychlor." []
synonym: "methoxychlor exposure" EXACT []
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6842 ! has exposure stimulus methoxychlor
relationship: RO:0002309 CHEBI:6842 ! has exposure stimulus methoxychlor

[Term]
id: ECTO:9001159
name: exposure to Methyl acrylate
def: "An exposure to Methyl acrylate." []
synonym: "Methyl acrylate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82482 ! has exposure stimulus Methyl acrylate
relationship: RO:0002309 CHEBI:82482 ! has exposure stimulus Methyl acrylate

[Term]
id: ECTO:9001160
name: obsolete methyl tert-butyl ether exposure
is_obsolete: true
replaced_by: ECTO:9000096

[Term]
id: ECTO:9001161
name: exposure to 4,4'-diaminodiphenylmethane
def: "An exposure to 4,4'-diaminodiphenylmethane." []
synonym: "4,4'-diaminodiphenylmethane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32506 ! has exposure stimulus 4,4'-diaminodiphenylmethane
relationship: RO:0002309 CHEBI:32506 ! has exposure stimulus 4,4'-diaminodiphenylmethane

[Term]
id: ECTO:9001162
name: exposure to O-methyleugenol
def: "An exposure to O-methyleugenol." []
synonym: "O-methyleugenol exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4918 ! has exposure stimulus O-methyleugenol
relationship: RO:0002309 CHEBI:4918 ! has exposure stimulus O-methyleugenol

[Term]
id: ECTO:9001163
name: exposure to iodomethane
def: "An exposure to iodomethane." []
synonym: "iodomethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39282 ! has exposure stimulus iodomethane
relationship: RO:0002309 CHEBI:39282 ! has exposure stimulus iodomethane

[Term]
id: ECTO:9001164
name: exposure to Methyl isobutyl ketone
def: "An exposure to Methyl isobutyl ketone." []
synonym: "Methyl isobutyl ketone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82344 ! has exposure stimulus Methyl isobutyl ketone
relationship: RO:0002309 CHEBI:82344 ! has exposure stimulus Methyl isobutyl ketone

[Term]
id: ECTO:9001165
name: exposure to methyl isocyanate
def: "An exposure to methyl isocyanate." []
synonym: "methyl isocyanate exposure" EXACT []
is_a: ECTO:9002153 ! exposure to isocyanates
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59059 ! has exposure stimulus methyl isocyanate
relationship: RO:0002309 CHEBI:59059 ! has exposure stimulus methyl isocyanate

[Term]
id: ECTO:9001166
name: exposure to methyl isothiocyanate
def: "An exposure to methyl isothiocyanate." []
synonym: "methyl isothiocyanate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78337 ! has exposure stimulus methyl isothiocyanate
relationship: RO:0002309 CHEBI:78337 ! has exposure stimulus methyl isothiocyanate

[Term]
id: ECTO:9001167
name: exposure to 2-hydroxy-2-methylpropanenitrile
def: "An exposure to 2-hydroxy-2-methylpropanenitrile." []
synonym: "2-hydroxy-2-methylpropanenitrile exposure" EXACT []
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15348 ! has exposure stimulus 2-hydroxy-2-methylpropanenitrile
relationship: RO:0002309 CHEBI:15348 ! has exposure stimulus 2-hydroxy-2-methylpropanenitrile

[Term]
id: ECTO:9001168
name: exposure to methyl methacrylate
def: "An exposure to methyl methacrylate." []
synonym: "methyl methacrylate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34840 ! has exposure stimulus methyl methacrylate
relationship: RO:0002309 CHEBI:34840 ! has exposure stimulus methyl methacrylate

[Term]
id: ECTO:9001169
name: exposure to N-Methylolacrylamide
def: "An exposure to N-Methylolacrylamide." []
synonym: "N-Methylolacrylamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82492 ! has exposure stimulus N-Methylolacrylamide
relationship: RO:0002309 CHEBI:82492 ! has exposure stimulus N-Methylolacrylamide

[Term]
id: ECTO:9001170
name: exposure to 2-methylpyridine
def: "An exposure to 2-methylpyridine." []
synonym: "2-methylpyridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50415 ! has exposure stimulus 2-methylpyridine
relationship: RO:0002309 CHEBI:50415 ! has exposure stimulus 2-methylpyridine

[Term]
id: ECTO:9001171
name: exposure to metiram
def: "An exposure to metiram." []
synonym: "metiram exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81539 ! has exposure stimulus metiram
relationship: RO:0002309 CHEBI:81539 ! has exposure stimulus metiram

[Term]
id: ECTO:9001172
name: exposure to mevinphos
def: "An exposure to mevinphos." []
synonym: "mevinphos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38725 ! has exposure stimulus mevinphos
relationship: RO:0002309 CHEBI:38725 ! has exposure stimulus mevinphos

[Term]
id: ECTO:9001173
name: exposure to Molinate
def: "An exposure to molinate." []
synonym: "molinate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6964 ! has exposure stimulus molinate
relationship: RO:0002309 CHEBI:6964 ! has exposure stimulus molinate

[Term]
id: ECTO:9001174
name: exposure to molybdenum trioxide
def: "An exposure to molybdenum trioxide." []
synonym: "molybdenum trioxide exposure" EXACT []
is_a: ECTO:9000948 ! exposure to molybdenum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30627 ! has exposure stimulus molybdenum trioxide
relationship: RO:0002309 CHEBI:30627 ! has exposure stimulus molybdenum trioxide

[Term]
id: ECTO:9001175
name: exposure to bis(2-chloroethyl) sulfide
def: "An exposure to bis(2-chloroethyl) sulfide." []
synonym: "bis(2-chloroethyl) sulfide exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25434 ! has exposure stimulus bis(2-chloroethyl) sulfide
relationship: RO:0002309 CHEBI:25434 ! has exposure stimulus bis(2-chloroethyl) sulfide

[Term]
id: ECTO:9001176
name: exposure to nabam
def: "An exposure to nabam." []
synonym: "nabam exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81934 ! has exposure stimulus nabam
relationship: RO:0002309 CHEBI:81934 ! has exposure stimulus nabam

[Term]
id: ECTO:9001177
name: exposure to naled
def: "An exposure to naled." []
synonym: "naled exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38729 ! has exposure stimulus naled
relationship: RO:0002309 CHEBI:38729 ! has exposure stimulus naled

[Term]
id: ECTO:9001178
name: exposure to 1-naphthylamine
def: "An exposure to 1-naphthylamine." []
synonym: "1-naphthylamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50450 ! has exposure stimulus 1-naphthylamine
relationship: RO:0002309 CHEBI:50450 ! has exposure stimulus 1-naphthylamine

[Term]
id: ECTO:9001179
name: exposure to 2-naphthylamine
def: "An exposure to 2-naphthylamine." []
synonym: "2-naphthylamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27878 ! has exposure stimulus 2-naphthylamine
relationship: RO:0002309 CHEBI:27878 ! has exposure stimulus 2-naphthylamine

[Term]
id: ECTO:9001181
name: exposure to Nitrapyrin
def: "An exposure to nitrapyrin." []
synonym: "nitrapyrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81935 ! has exposure stimulus nitrapyrin
relationship: RO:0002309 CHEBI:81935 ! has exposure stimulus nitrapyrin

[Term]
id: ECTO:9001183
name: exposure to nitrilotriacetic acid
def: "An exposure to nitrilotriacetic acid." []
synonym: "nitrilotriacetic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44557 ! has exposure stimulus nitrilotriacetic acid
relationship: RO:0002309 CHEBI:44557 ! has exposure stimulus nitrilotriacetic acid

[Term]
id: ECTO:9001184
name: exposure to 4-nitroaniline
def: "An exposure to 4-nitroaniline." []
synonym: "4-nitroaniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17064 ! has exposure stimulus 4-nitroaniline
relationship: RO:0002309 CHEBI:17064 ! has exposure stimulus 4-nitroaniline

[Term]
id: ECTO:9001185
name: exposure to 2-nitroanisole
def: "An exposure to 2-nitroanisole." []
synonym: "2-nitroanisole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48722 ! has exposure stimulus 2-nitroanisole
relationship: RO:0002309 CHEBI:48722 ! has exposure stimulus 2-nitroanisole

[Term]
id: ECTO:9001186
name: exposure to 2-methoxy-5-nitroaniline
def: "An exposure to 2-methoxy-5-nitroaniline." []
synonym: "2-methoxy-5-nitroaniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48977 ! has exposure stimulus 2-methoxy-5-nitroaniline
relationship: RO:0002309 CHEBI:48977 ! has exposure stimulus 2-methoxy-5-nitroaniline

[Term]
id: ECTO:9001187
name: exposure to 4-Nitrobiphenyl
def: "An exposure to 4-Nitrobiphenyl." []
synonym: "4-Nitrobiphenyl exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82504 ! has exposure stimulus 4-Nitrobiphenyl
relationship: RO:0002309 CHEBI:82504 ! has exposure stimulus 4-Nitrobiphenyl

[Term]
id: ECTO:9001188
name: exposure to Nitrofen
def: "An exposure to nitrofen." []
synonym: "nitrofen exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7590 ! has exposure stimulus nitrofen
relationship: RO:0002309 CHEBI:7590 ! has exposure stimulus nitrofen

[Term]
id: ECTO:9001189
name: exposure to 2-chloroethyl group
def: "An exposure to 2-chloroethyl group." []
synonym: "2-chloroethyl group exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47553 ! has exposure stimulus 2-chloroethyl group
relationship: RO:0002309 CHEBI:47553 ! has exposure stimulus 2-chloroethyl group

[Term]
id: ECTO:9001190
name: exposure to nitromethane
def: "An exposure to nitromethane." []
synonym: "nitromethane exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77701 ! has exposure stimulus nitromethane
relationship: RO:0002309 CHEBI:77701 ! has exposure stimulus nitromethane

[Term]
id: ECTO:9001191
name: exposure to 2-nitrophenol
def: "An exposure to 2-nitrophenol." []
synonym: "2-nitrophenol exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16260 ! has exposure stimulus 2-nitrophenol
relationship: RO:0002309 CHEBI:16260 ! has exposure stimulus 2-nitrophenol

[Term]
id: ECTO:9001192
name: exposure to 4-nitrophenol
def: "An exposure to 4-nitrophenol." []
synonym: "4-nitrophenol exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16836 ! has exposure stimulus 4-nitrophenol
relationship: RO:0002309 CHEBI:16836 ! has exposure stimulus 4-nitrophenol

[Term]
id: ECTO:9001193
name: exposure to 2-nitropropane
def: "An exposure to 2-nitropropane." []
synonym: "2-nitropropane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16037 ! has exposure stimulus 2-nitropropane
relationship: RO:0002309 CHEBI:16037 ! has exposure stimulus 2-nitropropane

[Term]
id: ECTO:9001194
name: exposure to N-Nitrosodi-n-butylamine
def: "An exposure to N-Nitrosodi-n-butylamine." []
synonym: "N-Nitrosodi-n-butylamine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82356 ! has exposure stimulus N-Nitrosodi-n-butylamine
relationship: RO:0002309 CHEBI:82356 ! has exposure stimulus N-Nitrosodi-n-butylamine

[Term]
id: ECTO:9001195
name: exposure to N-nitrosodiethylamine
def: "An exposure to N-nitrosodiethylamine." []
synonym: "N-nitrosodiethylamine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34873 ! has exposure stimulus N-nitrosodiethylamine
relationship: RO:0002309 CHEBI:34873 ! has exposure stimulus N-nitrosodiethylamine

[Term]
id: ECTO:9001196
name: exposure to N-nitrosodimethylamine
def: "An exposure to N-nitrosodimethylamine." []
synonym: "N-nitrosodimethylamine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35807 ! has exposure stimulus N-nitrosodimethylamine
relationship: RO:0002309 CHEBI:35807 ! has exposure stimulus N-nitrosodimethylamine

[Term]
id: ECTO:9001197
name: exposure to N-Nitrosodiphenylamine
def: "An exposure to N-Nitrosodiphenylamine." []
synonym: "N-Nitrosodiphenylamine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34875 ! has exposure stimulus N-Nitrosodiphenylamine
relationship: RO:0002309 CHEBI:34875 ! has exposure stimulus N-Nitrosodiphenylamine

[Term]
id: ECTO:9001198
name: exposure to N-Nitrosodi-n-propylamine
def: "An exposure to N-Nitrosodi-n-propylamine." []
synonym: "N-Nitrosodi-n-propylamine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82358 ! has exposure stimulus N-Nitrosodi-n-propylamine
relationship: RO:0002309 CHEBI:82358 ! has exposure stimulus N-Nitrosodi-n-propylamine

[Term]
id: ECTO:9001199
name: exposure to N-methyl-N-nitrosourea
def: "An exposure to N-methyl-N-nitrosourea." []
synonym: "N-methyl-N-nitrosourea exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50102 ! has exposure stimulus N-methyl-N-nitrosourea
relationship: RO:0002309 CHEBI:50102 ! has exposure stimulus N-methyl-N-nitrosourea

[Term]
id: ECTO:9001200
name: exposure to N-Nitrosomethylvinylamine
def: "An exposure to N-Nitrosomethylvinylamine." []
synonym: "N-Nitrosomethylvinylamine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82361 ! has exposure stimulus N-Nitrosomethylvinylamine
relationship: RO:0002309 CHEBI:82361 ! has exposure stimulus N-Nitrosomethylvinylamine

[Term]
id: ECTO:9001201
name: exposure to N-nitrosomorpholine
def: "An exposure to N-nitrosomorpholine." []
synonym: "N-nitrosomorpholine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76326 ! has exposure stimulus N-nitrosomorpholine
relationship: RO:0002309 CHEBI:76326 ! has exposure stimulus N-nitrosomorpholine

[Term]
id: ECTO:9001202
name: exposure to 5-nitro-o-toluidine
def: "An exposure to 5-nitro-o-toluidine." []
synonym: "5-nitro-o-toluidine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66891 ! has exposure stimulus 5-nitro-o-toluidine
relationship: RO:0002309 CHEBI:66891 ! has exposure stimulus 5-nitro-o-toluidine

[Term]
id: ECTO:9001203
name: exposure to norflurazon
def: "An exposure to norflurazon." []
synonym: "norflurazon exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50842 ! has exposure stimulus norflurazon
relationship: RO:0002309 CHEBI:50842 ! has exposure stimulus norflurazon

[Term]
id: ECTO:9001204
name: exposure to Octachlorostyrene
def: "An exposure to Octachlorostyrene." []
synonym: "Octachlorostyrene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81542 ! has exposure stimulus Octachlorostyrene
relationship: RO:0002309 CHEBI:81542 ! has exposure stimulus Octachlorostyrene

[Term]
id: ECTO:9001205
name: exposure to oryzalin
def: "An exposure to oryzalin." []
synonym: "oryzalin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73163 ! has exposure stimulus oryzalin
relationship: RO:0002309 CHEBI:73163 ! has exposure stimulus oryzalin

[Term]
id: ECTO:9001206
name: exposure to osmium tetroxide
def: "An exposure to osmium tetroxide." []
synonym: "osmium tetroxide exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88215 ! has exposure stimulus osmium tetroxide
relationship: RO:0002309 CHEBI:88215 ! has exposure stimulus osmium tetroxide

[Term]
id: ECTO:9001207
name: exposure to oxydemeton-methyl
def: "An exposure to oxydemeton-methyl." []
synonym: "oxydemeton-methyl exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38735 ! has exposure stimulus oxydemeton-methyl
relationship: RO:0002309 CHEBI:38735 ! has exposure stimulus oxydemeton-methyl

[Term]
id: ECTO:9001208
name: exposure to Oxyfluorfen
def: "An exposure to Oxyfluorfen." []
synonym: "Oxyfluorfen exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82029 ! has exposure stimulus Oxyfluorfen
relationship: RO:0002309 CHEBI:82029 ! has exposure stimulus Oxyfluorfen

[Term]
id: ECTO:9001209
name: exposure to paraldehyde
def: "An exposure to paraldehyde." []
synonym: "paraldehyde exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27909 ! has exposure stimulus paraldehyde
relationship: RO:0002309 CHEBI:27909 ! has exposure stimulus paraldehyde

[Term]
id: ECTO:9001210
name: exposure to paraquat dichloride
def: "An exposure to paraquat dichloride." []
synonym: "paraquat dichloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28786 ! has exposure stimulus paraquat dichloride
relationship: RO:0002309 CHEBI:28786 ! has exposure stimulus paraquat dichloride

[Term]
id: ECTO:9001211
name: exposure to p-nitrophenyl group
def: "An exposure to p-nitrophenyl group." []
synonym: "p-nitrophenyl group exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61595 ! has exposure stimulus p-nitrophenyl group
relationship: RO:0002309 CHEBI:61595 ! has exposure stimulus p-nitrophenyl group

[Term]
id: ECTO:9001212
name: exposure to Pebulate
def: "An exposure to Pebulate." []
synonym: "Pebulate exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81939 ! has exposure stimulus Pebulate
relationship: RO:0002309 CHEBI:81939 ! has exposure stimulus Pebulate

[Term]
id: ECTO:9001213
name: exposure to pentan-3-yl group
def: "An exposure to pentan-3-yl group." []
synonym: "pentan-3-yl group exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32881 ! has exposure stimulus pentan-3-yl group
relationship: RO:0002309 CHEBI:32881 ! has exposure stimulus pentan-3-yl group

[Term]
id: ECTO:9001214
name: exposure to pentachloroethane
def: "An exposure to pentachloroethane." []
synonym: "pentachloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76287 ! has exposure stimulus pentachloroethane
relationship: RO:0002309 CHEBI:76287 ! has exposure stimulus pentachloroethane

[Term]
id: ECTO:9001215
name: exposure to pentachlorophenol
def: "An exposure to pentachlorophenol." []
synonym: "pentachlorophenol exposure" EXACT []
is_a: ECTO:9001308 ! exposure to chlorophenol
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17642 ! has exposure stimulus pentachlorophenol
relationship: RO:0002309 CHEBI:17642 ! has exposure stimulus pentachlorophenol

[Term]
id: ECTO:9001216
name: exposure to Pentobarbital sodium
def: "An exposure to Pentobarbital sodium." []
synonym: "Pentobarbital sodium exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7984 ! has exposure stimulus Pentobarbital sodium
relationship: RO:0002309 CHEBI:7984 ! has exposure stimulus Pentobarbital sodium

[Term]
id: ECTO:9001217
name: exposure to permethrin
def: "An exposure to permethrin." []
synonym: "permethrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34911 ! has exposure stimulus permethrin
relationship: RO:0002309 CHEBI:34911 ! has exposure stimulus permethrin

[Term]
id: ECTO:9001218
name: obsolete phenol exposure
is_obsolete: true
replaced_by: ECTO:9000071

[Term]
id: ECTO:9001219
name: exposure to phenolphthalein
def: "An exposure to phenolphthalein." []
synonym: "phenolphthalein exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34914 ! has exposure stimulus phenolphthalein
relationship: RO:0002309 CHEBI:34914 ! has exposure stimulus phenolphthalein

[Term]
id: ECTO:9001220
name: exposure to phenothrin
def: "An exposure to phenothrin." []
synonym: "phenothrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34916 ! has exposure stimulus phenothrin
relationship: RO:0002309 CHEBI:34916 ! has exposure stimulus phenothrin

[Term]
id: ECTO:9001221
name: exposure to 1,2-phenylenediamine
def: "An exposure to 1,2-phenylenediamine." []
synonym: "1,2-phenylenediamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34043 ! has exposure stimulus 1,2-phenylenediamine
relationship: RO:0002309 CHEBI:34043 ! has exposure stimulus 1,2-phenylenediamine

[Term]
id: ECTO:9001222
name: exposure to 1,3-phenylenediamine
def: "An exposure to 1,3-phenylenediamine." []
synonym: "1,3-phenylenediamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8092 ! has exposure stimulus 1,3-phenylenediamine
relationship: RO:0002309 CHEBI:8092 ! has exposure stimulus 1,3-phenylenediamine

[Term]
id: ECTO:9001223
name: exposure to 1,4-phenylenediamine
def: "An exposure to 1,4-phenylenediamine." []
synonym: "1,4-phenylenediamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51403 ! has exposure stimulus 1,4-phenylenediamine
relationship: RO:0002309 CHEBI:51403 ! has exposure stimulus 1,4-phenylenediamine

[Term]
id: ECTO:9001224
name: exposure to phenytoin
def: "An exposure to phenytoin." []
synonym: "phenytoin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8107 ! has exposure stimulus phenytoin
relationship: RO:0002309 CHEBI:8107 ! has exposure stimulus phenytoin

[Term]
id: ECTO:9001225
name: obsolete phosgene exposure
is_obsolete: true
replaced_by: ECTO:9000070

[Term]
id: ECTO:9001226
name: exposure to phosphine
def: "An exposure to phosphine." []
synonym: "phosphine exposure" EXACT []
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35883 ! has exposure stimulus phosphine
relationship: RO:0002309 CHEBI:35883 ! has exposure stimulus phosphine

[Term]
id: ECTO:9001227
name: exposure to phosphorus
def: "An exposure to phosphorus molecular entity." []
synonym: "phosphorus molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26082 ! has exposure stimulus phosphorus molecular entity
relationship: RO:0002309 CHEBI:26082 ! has exposure stimulus phosphorus molecular entity

[Term]
id: ECTO:9001228
name: exposure to phthalic anhydride
def: "An exposure to phthalic anhydride." []
synonym: "phthalic anhydride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36605 ! has exposure stimulus phthalic anhydride
relationship: RO:0002309 CHEBI:36605 ! has exposure stimulus phthalic anhydride

[Term]
id: ECTO:9001229
name: exposure to Picloram
def: "An exposure to picloram." []
synonym: "picloram exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34922 ! has exposure stimulus picloram
relationship: RO:0002309 CHEBI:34922 ! has exposure stimulus picloram

[Term]
id: ECTO:9001230
name: exposure to picric acid
def: "An exposure to picric acid." []
synonym: "picric acid exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46149 ! has exposure stimulus picric acid
relationship: RO:0002309 CHEBI:46149 ! has exposure stimulus picric acid

[Term]
id: ECTO:9001231
name: exposure to piperonyl butoxide
def: "An exposure to piperonyl butoxide." []
synonym: "piperonyl butoxide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32687 ! has exposure stimulus piperonyl butoxide
relationship: RO:0002309 CHEBI:32687 ! has exposure stimulus piperonyl butoxide

[Term]
id: ECTO:9001232
name: exposure to potassium bromate
def: "An exposure to potassium bromate." []
synonym: "potassium bromate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38211 ! has exposure stimulus potassium bromate
relationship: RO:0002309 CHEBI:38211 ! has exposure stimulus potassium bromate

[Term]
id: ECTO:9001233
name: exposure to profenofos
def: "An exposure to profenofos." []
synonym: "profenofos exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38845 ! has exposure stimulus profenofos
relationship: RO:0002309 CHEBI:38845 ! has exposure stimulus profenofos

[Term]
id: ECTO:9001234
name: exposure to isopropyl group
def: "An exposure to isopropyl group." []
synonym: "isopropyl group exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30353 ! has exposure stimulus isopropyl group
relationship: RO:0002309 CHEBI:30353 ! has exposure stimulus isopropyl group

[Term]
id: ECTO:9001235
name: exposure to Pronamide
def: "An exposure to propyzamide." []
synonym: "propyzamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34935 ! has exposure stimulus propyzamide
relationship: RO:0002309 CHEBI:34935 ! has exposure stimulus propyzamide

[Term]
id: ECTO:9001236
name: exposure to propargite
def: "An exposure to propargite." []
synonym: "propargite exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39300 ! has exposure stimulus propargite
relationship: RO:0002309 CHEBI:39300 ! has exposure stimulus propargite

[Term]
id: ECTO:9001237
name: exposure to prop-2-yn-1-ol
def: "An exposure to prop-2-yn-1-ol." []
synonym: "prop-2-yn-1-ol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28905 ! has exposure stimulus prop-2-yn-1-ol
relationship: RO:0002309 CHEBI:28905 ! has exposure stimulus prop-2-yn-1-ol

[Term]
id: ECTO:9001238
name: exposure to propetamphos
def: "An exposure to propetamphos." []
synonym: "propetamphos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38864 ! has exposure stimulus propetamphos
relationship: RO:0002309 CHEBI:38864 ! has exposure stimulus propetamphos

[Term]
id: ECTO:9001239
name: exposure to beta-propiolactone
def: "An exposure to beta-propiolactone." []
synonym: "beta-propiolactone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49073 ! has exposure stimulus beta-propiolactone
relationship: RO:0002309 CHEBI:49073 ! has exposure stimulus beta-propiolactone

[Term]
id: ECTO:9001240
name: exposure to propanal
def: "An exposure to propanal." []
synonym: "propanal exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17153 ! has exposure stimulus propanal
relationship: RO:0002309 CHEBI:17153 ! has exposure stimulus propanal

[Term]
id: ECTO:9001241
name: exposure to propoxur
def: "An exposure to propoxur." []
synonym: "propoxur exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34938 ! has exposure stimulus propoxur
relationship: RO:0002309 CHEBI:34938 ! has exposure stimulus propoxur

[Term]
id: ECTO:9001242
name: exposure to propene
def: "An exposure to propene." []
synonym: "propene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16052 ! has exposure stimulus propene
relationship: RO:0002309 CHEBI:16052 ! has exposure stimulus propene

[Term]
id: ECTO:9001243
name: exposure to 2-Methylaziridine
def: "An exposure to 2-Methylaziridine." []
synonym: "2-Methylaziridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82340 ! has exposure stimulus 2-Methylaziridine
relationship: RO:0002309 CHEBI:82340 ! has exposure stimulus 2-Methylaziridine

[Term]
id: ECTO:9001244
name: exposure to 1,2-epoxypropane
def: "An exposure to 1,2-epoxypropane." []
synonym: "1,2-epoxypropane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38685 ! has exposure stimulus 1,2-epoxypropane
relationship: RO:0002309 CHEBI:38685 ! has exposure stimulus 1,2-epoxypropane

[Term]
id: ECTO:9001245
name: exposure to quinoline
def: "An exposure to quinoline." []
synonym: "quinoline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17362 ! has exposure stimulus quinoline
relationship: RO:0002309 CHEBI:17362 ! has exposure stimulus quinoline

[Term]
id: ECTO:9001246
name: exposure to quinone
def: "An exposure to quinone." []
synonym: "quinone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36141 ! has exposure stimulus quinone
relationship: RO:0002309 CHEBI:36141 ! has exposure stimulus quinone

[Term]
id: ECTO:9001247
name: exposure to pentachloronitrobenzene
def: "An exposure to pentachloronitrobenzene." []
synonym: "pentachloronitrobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34908 ! has exposure stimulus pentachloronitrobenzene
relationship: RO:0002309 CHEBI:34908 ! has exposure stimulus pentachloronitrobenzene

[Term]
id: ECTO:9001248
name: exposure to Quizalofop-ethyl
def: "An exposure to quizalofop-ethyl." []
synonym: "quizalofop-ethyl exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81807 ! has exposure stimulus quizalofop-ethyl
relationship: RO:0002309 CHEBI:81807 ! has exposure stimulus quizalofop-ethyl

[Term]
id: ECTO:9001249
name: exposure to resmethrin
def: "An exposure to resmethrin." []
synonym: "resmethrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8811 ! has exposure stimulus resmethrin
relationship: RO:0002309 CHEBI:8811 ! has exposure stimulus resmethrin

[Term]
id: ECTO:9001250
name: exposure to safrole
def: "An exposure to safrole." []
synonym: "safrole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8994 ! has exposure stimulus safrole
relationship: RO:0002309 CHEBI:8994 ! has exposure stimulus safrole

[Term]
id: ECTO:9001251
name: exposure to Sethoxydim
def: "An exposure to Sethoxydim." []
synonym: "Sethoxydim exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81815 ! has exposure stimulus Sethoxydim
relationship: RO:0002309 CHEBI:81815 ! has exposure stimulus Sethoxydim

[Term]
id: ECTO:9001252
name: exposure to elemental silver
def: "An exposure to elemental silver." []
synonym: "elemental silver exposure" EXACT []
is_a: ECTO:9001311 ! exposure to silver
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33966 ! has exposure stimulus elemental silver
relationship: RO:0002309 CHEBI:33966 ! has exposure stimulus elemental silver

[Term]
id: ECTO:9001253
name: exposure to sodium azide
def: "An exposure to sodium azide." []
synonym: "sodium azide exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:278547 ! has exposure stimulus sodium azide
relationship: RO:0002309 CHEBI:278547 ! has exposure stimulus sodium azide

[Term]
id: ECTO:9001254
name: exposure to sodium fluoroacetate
def: "An exposure to sodium fluoroacetate." []
synonym: "sodium fluoroacetate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38699 ! has exposure stimulus sodium fluoroacetate
relationship: RO:0002309 CHEBI:38699 ! has exposure stimulus sodium fluoroacetate

[Term]
id: ECTO:9001255
name: exposure to sodium nitrite
def: "An exposure to sodium nitrite." []
synonym: "sodium nitrite exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78870 ! has exposure stimulus sodium nitrite
relationship: RO:0002309 CHEBI:78870 ! has exposure stimulus sodium nitrite

[Term]
id: ECTO:9001256
name: exposure to styrene oxide
def: "An exposure to styrene oxide." []
synonym: "styrene oxide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17907 ! has exposure stimulus styrene oxide
relationship: RO:0002309 CHEBI:17907 ! has exposure stimulus styrene oxide

[Term]
id: ECTO:9001258
name: exposure to sulfuryl difluoride
def: "An exposure to sulfuryl difluoride." []
synonym: "sulfuryl difluoride exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39287 ! has exposure stimulus sulfuryl difluoride
relationship: RO:0002309 CHEBI:39287 ! has exposure stimulus sulfuryl difluoride

[Term]
id: ECTO:9001259
name: exposure to sulprofos
def: "An exposure to sulprofos." []
synonym: "sulprofos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38949 ! has exposure stimulus sulprofos
relationship: RO:0002309 CHEBI:38949 ! has exposure stimulus sulprofos

[Term]
id: ECTO:9001260
name: exposure to tert-butyl group
def: "An exposure to tert-butyl group." []
synonym: "tert-butyl group exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30355 ! has exposure stimulus tert-butyl group
relationship: RO:0002309 CHEBI:30355 ! has exposure stimulus tert-butyl group

[Term]
id: ECTO:9001261
name: exposure to temephos
def: "An exposure to temephos." []
synonym: "temephos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38954 ! has exposure stimulus temephos
relationship: RO:0002309 CHEBI:38954 ! has exposure stimulus temephos

[Term]
id: ECTO:9001262
name: exposure to Terbacil
def: "An exposure to Terbacil." []
synonym: "Terbacil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9447 ! has exposure stimulus Terbacil
relationship: RO:0002309 CHEBI:9447 ! has exposure stimulus Terbacil

[Term]
id: ECTO:9001263
name: exposure to 3,3',5,5'-tetrabromobisphenol A
def: "An exposure to 3,3',5,5'-tetrabromobisphenol A." []
synonym: "3,3',5,5'-tetrabromobisphenol A exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
is_a: ECTO:9002162 ! exposure to brominated flame retardant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33217 ! has exposure stimulus 3,3',5,5'-tetrabromobisphenol A
relationship: RO:0002309 CHEBI:33217 ! has exposure stimulus 3,3',5,5'-tetrabromobisphenol A

[Term]
id: ECTO:9001264
name: exposure to 1,1,1,2-tetrachloroethane
def: "An exposure to 1,1,1,2-tetrachloroethane." []
synonym: "1,1,1,2-tetrachloroethane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34024 ! has exposure stimulus 1,1,1,2-tetrachloroethane
relationship: RO:0002309 CHEBI:34024 ! has exposure stimulus 1,1,1,2-tetrachloroethane

[Term]
id: ECTO:9001265
name: exposure to tetrachlorvinphos
def: "An exposure to tetrachlorvinphos." []
synonym: "tetrachlorvinphos exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35005 ! has exposure stimulus tetrachlorvinphos
relationship: RO:0002309 CHEBI:35005 ! has exposure stimulus tetrachlorvinphos

[Term]
id: ECTO:9001266
name: exposure to Tetracycline hydrochloride
def: "An exposure to Tetracycline hydrochloride." []
synonym: "Tetracycline hydrochloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35006 ! has exposure stimulus Tetracycline hydrochloride
relationship: RO:0002309 CHEBI:35006 ! has exposure stimulus Tetracycline hydrochloride

[Term]
id: ECTO:9001267
name: exposure to tetrafluoroethene
def: "An exposure to tetrafluoroethene." []
synonym: "tetrafluoroethene exposure" EXACT []
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38866 ! has exposure stimulus tetrafluoroethene
relationship: RO:0002309 CHEBI:38866 ! has exposure stimulus tetrafluoroethene

[Term]
id: ECTO:9001268
name: exposure to Tetranitromethane
def: "An exposure to Tetranitromethane." []
synonym: "Tetranitromethane exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82372 ! has exposure stimulus Tetranitromethane
relationship: RO:0002309 CHEBI:82372 ! has exposure stimulus Tetranitromethane

[Term]
id: ECTO:9001269
name: exposure to tetramethrin
def: "An exposure to tetramethrin." []
synonym: "tetramethrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39397 ! has exposure stimulus tetramethrin
relationship: RO:0002309 CHEBI:39397 ! has exposure stimulus tetramethrin

[Term]
id: ECTO:9001270
name: exposure to thioacetamide
def: "An exposure to thioacetamide." []
synonym: "thioacetamide exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32497 ! has exposure stimulus thioacetamide
relationship: RO:0002309 CHEBI:32497 ! has exposure stimulus thioacetamide

[Term]
id: ECTO:9001271
name: exposure to Thiobencarb
def: "An exposure to Thiobencarb." []
synonym: "Thiobencarb exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35011 ! has exposure stimulus Thiobencarb
relationship: RO:0002309 CHEBI:35011 ! has exposure stimulus Thiobencarb

[Term]
id: ECTO:9001272
name: exposure to 4,4'-Thiodianiline
def: "An exposure to 4,4'-Thiodianiline." []
synonym: "4,4'-Thiodianiline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82374 ! has exposure stimulus 4,4'-Thiodianiline
relationship: RO:0002309 CHEBI:82374 ! has exposure stimulus 4,4'-Thiodianiline

[Term]
id: ECTO:9001273
name: exposure to thiodicarb
def: "An exposure to thiodicarb." []
synonym: "thiodicarb exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38548 ! has exposure stimulus thiodicarb
relationship: RO:0002309 CHEBI:38548 ! has exposure stimulus thiodicarb

[Term]
id: ECTO:9001274
name: exposure to thiourea
def: "An exposure to thiourea." []
synonym: "thiourea exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36946 ! has exposure stimulus thiourea
relationship: RO:0002309 CHEBI:36946 ! has exposure stimulus thiourea

[Term]
id: ECTO:9001275
name: exposure to thiram
def: "An exposure to thiram." []
synonym: "thiram exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9495 ! has exposure stimulus thiram
relationship: RO:0002309 CHEBI:9495 ! has exposure stimulus thiram

[Term]
id: ECTO:9001276
name: exposure to thorium dioxide
def: "An exposure to thorium dioxide." []
synonym: "thorium dioxide exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37339 ! has exposure stimulus thorium dioxide
relationship: RO:0002309 CHEBI:37339 ! has exposure stimulus thorium dioxide

[Term]
id: ECTO:9001278
name: exposure to o-toluidine
def: "An exposure to o-toluidine." []
synonym: "o-toluidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66892 ! has exposure stimulus o-toluidine
relationship: RO:0002309 CHEBI:66892 ! has exposure stimulus o-toluidine

[Term]
id: ECTO:9001279
name: exposure to triadimefon
def: "An exposure to triadimefon." []
synonym: "triadimefon exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9665 ! has exposure stimulus triadimefon
relationship: RO:0002309 CHEBI:9665 ! has exposure stimulus triadimefon

[Term]
id: ECTO:9001280
name: exposure to Tri-allate
def: "An exposure to Tri-allate." []
synonym: "Tri-allate exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81978 ! has exposure stimulus Tri-allate
relationship: RO:0002309 CHEBI:81978 ! has exposure stimulus Tri-allate

[Term]
id: ECTO:9001281
name: exposure to triaziquone
def: "An exposure to triaziquone." []
synonym: "triaziquone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27090 ! has exposure stimulus triaziquone
relationship: RO:0002309 CHEBI:27090 ! has exposure stimulus triaziquone

[Term]
id: ECTO:9001282
name: exposure to tribenuron methyl
def: "An exposure to tribenuron methyl." []
synonym: "tribenuron methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9678 ! has exposure stimulus tribenuron methyl
relationship: RO:0002309 CHEBI:9678 ! has exposure stimulus tribenuron methyl

[Term]
id: ECTO:9001283
name: exposure to tribufos
def: "An exposure to tribufos." []
synonym: "tribufos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38737 ! has exposure stimulus tribufos
relationship: RO:0002309 CHEBI:38737 ! has exposure stimulus tribufos

[Term]
id: ECTO:9001284
name: exposure to trichlorfon
def: "An exposure to trichlorfon." []
synonym: "trichlorfon exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6908 ! has exposure stimulus trichlorfon
relationship: RO:0002309 CHEBI:6908 ! has exposure stimulus trichlorfon

[Term]
id: ECTO:9001285
name: exposure to 1,2,4-trichlorobenzene
def: "An exposure to 1,2,4-trichlorobenzene." []
synonym: "1,2,4-trichlorobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28222 ! has exposure stimulus 1,2,4-trichlorobenzene
relationship: RO:0002309 CHEBI:28222 ! has exposure stimulus 1,2,4-trichlorobenzene

[Term]
id: ECTO:9001286
name: exposure to 2,4,5-trichlorophenol
def: "An exposure to 2,4,5-trichlorophenol." []
synonym: "2,4,5-trichlorophenol exposure" EXACT []
is_a: ECTO:9001308 ! exposure to chlorophenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28520 ! has exposure stimulus 2,4,5-trichlorophenol
relationship: RO:0002309 CHEBI:28520 ! has exposure stimulus 2,4,5-trichlorophenol

[Term]
id: ECTO:9001287
name: exposure to 2,4,6-trichlorophenol
def: "An exposure to 2,4,6-trichlorophenol." []
synonym: "2,4,6-trichlorophenol exposure" EXACT []
is_a: ECTO:9001308 ! exposure to chlorophenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28755 ! has exposure stimulus 2,4,6-trichlorophenol
relationship: RO:0002309 CHEBI:28755 ! has exposure stimulus 2,4,6-trichlorophenol

[Term]
id: ECTO:9001288
name: exposure to 1,2,3-Trichloropropane
def: "An exposure to 1,2,3-Trichloropropane." []
synonym: "1,2,3-Trichloropropane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34036 ! has exposure stimulus 1,2,3-Trichloropropane
relationship: RO:0002309 CHEBI:34036 ! has exposure stimulus 1,2,3-Trichloropropane

[Term]
id: ECTO:9001289
name: exposure to triethylamine
def: "An exposure to triethylamine." []
synonym: "triethylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35026 ! has exposure stimulus triethylamine
relationship: RO:0002309 CHEBI:35026 ! has exposure stimulus triethylamine

[Term]
id: ECTO:9001290
name: exposure to triforine
def: "An exposure to triforine." []
synonym: "triforine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9715 ! has exposure stimulus triforine
relationship: RO:0002309 CHEBI:9715 ! has exposure stimulus triforine

[Term]
id: ECTO:9001291
name: exposure to 1,2,4-trimethylbenzene
def: "An exposure to 1,2,4-trimethylbenzene." []
synonym: "1,2,4-trimethylbenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34039 ! has exposure stimulus 1,2,4-trimethylbenzene
relationship: RO:0002309 CHEBI:34039 ! has exposure stimulus 1,2,4-trimethylbenzene

[Term]
id: ECTO:9001292
name: exposure to 2,3,5-trimethylphenyl methylcarbamate
def: "An exposure to 2,3,5-trimethylphenyl methylcarbamate." []
synonym: "2,3,5-trimethylphenyl methylcarbamate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38893 ! has exposure stimulus 2,3,5-trimethylphenyl methylcarbamate
relationship: RO:0002309 CHEBI:38893 ! has exposure stimulus 2,3,5-trimethylphenyl methylcarbamate

[Term]
id: ECTO:9001293
name: exposure to fentin chloride
def: "An exposure to fentin chloride." []
synonym: "fentin chloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9001388 ! exposure to organotin compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35036 ! has exposure stimulus fentin chloride
relationship: RO:0002309 CHEBI:35036 ! has exposure stimulus fentin chloride

[Term]
id: ECTO:9001294
name: exposure to fentin hydroxide
def: "An exposure to fentin hydroxide." []
synonym: "fentin hydroxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001388 ! exposure to organotin compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30473 ! has exposure stimulus fentin hydroxide
relationship: RO:0002309 CHEBI:30473 ! has exposure stimulus fentin hydroxide

[Term]
id: ECTO:9001295
name: exposure to Tris(2,3-dibromopropyl) phosphate
def: "An exposure to tris(2,3-dibromopropyl) phosphate." []
synonym: "tris(2,3-dibromopropyl) phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
is_a: ECTO:9002162 ! exposure to brominated flame retardant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82282 ! has exposure stimulus tris(2,3-dibromopropyl) phosphate
relationship: RO:0002309 CHEBI:82282 ! has exposure stimulus tris(2,3-dibromopropyl) phosphate

[Term]
id: ECTO:9001296
name: exposure to trypan blue
def: "An exposure to trypan blue." []
synonym: "trypan blue exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78897 ! has exposure stimulus trypan blue
relationship: RO:0002309 CHEBI:78897 ! has exposure stimulus trypan blue

[Term]
id: ECTO:9001298
name: exposure to vanadium
def: "An exposure to vanadium molecular entity." []
synonym: "vanadium molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27275 ! has exposure stimulus vanadium molecular entity
relationship: RO:0002309 CHEBI:27275 ! has exposure stimulus vanadium molecular entity

[Term]
id: ECTO:9001299
name: exposure to vinclozolin
def: "An exposure to vinclozolin." []
synonym: "vinclozolin exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9986 ! has exposure stimulus vinclozolin
relationship: RO:0002309 CHEBI:9986 ! has exposure stimulus vinclozolin

[Term]
id: ECTO:9001300
name: exposure to vinyl acetate
def: "An exposure to vinyl acetate." []
synonym: "vinyl acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46916 ! has exposure stimulus vinyl acetate
relationship: RO:0002309 CHEBI:46916 ! has exposure stimulus vinyl acetate

[Term]
id: ECTO:9001301
name: exposure to bromoethene
def: "An exposure to bromoethene." []
synonym: "bromoethene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51311 ! has exposure stimulus bromoethene
relationship: RO:0002309 CHEBI:51311 ! has exposure stimulus bromoethene

[Term]
id: ECTO:9001302
name: exposure to chloroethene
def: "An exposure to chloroethene." []
synonym: "chloroethene exposure" EXACT []
synonym: "exposure to vinyl chloride" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28509 ! has exposure stimulus chloroethene
relationship: RO:0002309 CHEBI:28509 ! has exposure stimulus chloroethene

[Term]
id: ECTO:9001303
name: exposure to fluoroethene
def: "An exposure to fluoroethene." []
synonym: "fluoroethene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51314 ! has exposure stimulus fluoroethene
relationship: RO:0002309 CHEBI:51314 ! has exposure stimulus fluoroethene

[Term]
id: ECTO:9001304
name: exposure to m-xylene
def: "An exposure to m-xylene." []
synonym: "m-xylene exposure" EXACT []
is_a: ECTO:9000035 ! exposure to xylene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28488 ! has exposure stimulus m-xylene
relationship: RO:0002309 CHEBI:28488 ! has exposure stimulus m-xylene

[Term]
id: ECTO:9001305
name: exposure to 2,6-dimethylaniline
def: "An exposure to 2,6-dimethylaniline." []
synonym: "2,6-dimethylaniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28738 ! has exposure stimulus 2,6-dimethylaniline
relationship: RO:0002309 CHEBI:28738 ! has exposure stimulus 2,6-dimethylaniline

[Term]
id: ECTO:9001306
name: exposure to elemental zinc
def: "An exposure to elemental zinc." []
synonym: "elemental zinc exposure" EXACT []
is_a: ECTO:9000954 ! exposure to zinc
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37253 ! has exposure stimulus elemental zinc
relationship: RO:0002309 CHEBI:37253 ! has exposure stimulus elemental zinc

[Term]
id: ECTO:9001307
name: exposure to zineb
def: "An exposure to zineb." []
synonym: "zineb exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9000954 ! exposure to zinc
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52498 ! has exposure stimulus zineb
relationship: RO:0002309 CHEBI:52498 ! has exposure stimulus zineb

[Term]
id: ECTO:9001308
name: exposure to chlorophenol
def: "An exposure to chlorophenol." []
synonym: "chlorophenol exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23150 ! has exposure stimulus chlorophenol
relationship: RO:0002309 CHEBI:23150 ! has exposure stimulus chlorophenol

[Term]
id: ECTO:9001309
name: exposure to diisocyanate
def: "An exposure to diisocyanate." []
synonym: "diisocyanate exposure" EXACT []
is_a: ECTO:9002153 ! exposure to isocyanates
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53213 ! has exposure stimulus diisocyanate
relationship: RO:0002309 CHEBI:53213 ! has exposure stimulus diisocyanate

[Term]
id: ECTO:9001310
name: obsolete nickel molecular entity exposure
is_obsolete: true
replaced_by: ECTO:9000063

[Term]
id: ECTO:9001311
name: exposure to silver
def: "An exposure to silver molecular entity." []
synonym: "silver molecular entity exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33964 ! has exposure stimulus silver molecular entity
relationship: RO:0002309 CHEBI:33964 ! has exposure stimulus silver molecular entity

[Term]
id: ECTO:9001312
name: exposure to thallium
def: "An exposure to thallium molecular entity." []
synonym: "thallium molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37110 ! has exposure stimulus thallium molecular entity
relationship: RO:0002309 CHEBI:37110 ! has exposure stimulus thallium molecular entity

[Term]
id: ECTO:9001313
name: exposure to elemental boron
def: "An exposure to elemental boron." []
synonym: "elemental boron exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000173 ! exposure to boron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33609 ! has exposure stimulus elemental boron
relationship: RO:0002309 CHEBI:33609 ! has exposure stimulus elemental boron

[Term]
id: ECTO:9001315
name: exposure to L-lysine
def: "An exposure to L-lysine." []
synonym: "L-lysine exposure" EXACT []
is_a: ECTO:9002767 ! exposure to lysine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18019 ! has exposure stimulus L-lysine
relationship: RO:0002309 CHEBI:18019 ! has exposure stimulus L-lysine

[Term]
id: ECTO:9001316
name: exposure to benzo[a]pyrene
def: "An exposure to benzo[a]pyrene." []
synonym: "benzo[a]pyrene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29865 ! has exposure stimulus benzo[a]pyrene
relationship: RO:0002309 CHEBI:29865 ! has exposure stimulus benzo[a]pyrene

[Term]
id: ECTO:9001317
name: exposure to 1,6-Dinitropyrene
def: "An exposure to 1,6-Dinitropyrene." []
synonym: "1,6-Dinitropyrene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34066 ! has exposure stimulus 1,6-Dinitropyrene
relationship: RO:0002309 CHEBI:34066 ! has exposure stimulus 1,6-Dinitropyrene

[Term]
id: ECTO:9001318
name: exposure to 1,8-Dinitropyrene
def: "An exposure to 1,8-Dinitropyrene." []
synonym: "1,8-Dinitropyrene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34069 ! has exposure stimulus 1,8-Dinitropyrene
relationship: RO:0002309 CHEBI:34069 ! has exposure stimulus 1,8-Dinitropyrene

[Term]
id: ECTO:9001319
name: exposure to 5-Methylchrysene
def: "An exposure to 5-Methylchrysene." []
synonym: "5-Methylchrysene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82342 ! has exposure stimulus 5-Methylchrysene
relationship: RO:0002309 CHEBI:82342 ! has exposure stimulus 5-Methylchrysene

[Term]
id: ECTO:9001320
name: exposure to 6-Nitrochrysene
def: "An exposure to 6-Nitrochrysene." []
synonym: "6-Nitrochrysene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82351 ! has exposure stimulus 6-Nitrochrysene
relationship: RO:0002309 CHEBI:82351 ! has exposure stimulus 6-Nitrochrysene

[Term]
id: ECTO:9001321
name: exposure to 1-nitropyrene
def: "An exposure to 1-nitropyrene." []
synonym: "1-nitropyrene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34107 ! has exposure stimulus 1-nitropyrene
relationship: RO:0002309 CHEBI:34107 ! has exposure stimulus 1-nitropyrene

[Term]
id: ECTO:9001322
name: exposure to 4-Nitropyrene
def: "An exposure to 4-Nitropyrene." []
synonym: "4-Nitropyrene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82355 ! has exposure stimulus 4-Nitropyrene
relationship: RO:0002309 CHEBI:82355 ! has exposure stimulus 4-Nitropyrene

[Term]
id: ECTO:9001323
name: exposure to 3,3'-Dimethoxybenzidine-4,4'-diisocyanate
def: "An exposure to 3,3'-Dimethoxybenzidine-4,4'-diisocyanate." []
synonym: "3,3'-Dimethoxybenzidine-4,4'-diisocyanate exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82451 ! has exposure stimulus 3,3'-Dimethoxybenzidine-4,4'-diisocyanate
relationship: RO:0002309 CHEBI:82451 ! has exposure stimulus 3,3'-Dimethoxybenzidine-4,4'-diisocyanate

[Term]
id: ECTO:9001324
name: exposure to hexamethylene diisocyanate
def: "An exposure to hexamethylene diisocyanate." []
synonym: "hexamethylene diisocyanate exposure" EXACT []
is_a: ECTO:9001309 ! exposure to diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53578 ! has exposure stimulus hexamethylene diisocyanate
relationship: RO:0002309 CHEBI:53578 ! has exposure stimulus hexamethylene diisocyanate

[Term]
id: ECTO:9001325
name: exposure to isophorone diisocyanate
def: "An exposure to isophorone diisocyanate." []
synonym: "isophorone diisocyanate exposure" EXACT []
is_a: ECTO:9001309 ! exposure to diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53214 ! has exposure stimulus isophorone diisocyanate
relationship: RO:0002309 CHEBI:53214 ! has exposure stimulus isophorone diisocyanate

[Term]
id: ECTO:9001326
name: exposure to 1,5-Naphthalene diisocyanate
def: "An exposure to 1,5-Naphthalene diisocyanate." []
synonym: "1,5-Naphthalene diisocyanate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82496 ! has exposure stimulus 1,5-Naphthalene diisocyanate
relationship: RO:0002309 CHEBI:82496 ! has exposure stimulus 1,5-Naphthalene diisocyanate

[Term]
id: ECTO:9001327
name: exposure to 1,2,3,4,7,8-Hexachlorodibenzodioxin
def: "An exposure to 1,2,3,4,7,8-Hexachlorodibenzodioxin." []
synonym: "1,2,3,4,7,8-Hexachlorodibenzodioxin exposure" EXACT []
is_a: ECTO:9001625 ! exposure to polychlorinated dibenzodioxine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81502 ! has exposure stimulus 1,2,3,4,7,8-Hexachlorodibenzodioxin
relationship: RO:0002309 CHEBI:81502 ! has exposure stimulus 1,2,3,4,7,8-Hexachlorodibenzodioxin

[Term]
id: ECTO:9001328
name: exposure to 1,2,3,6,7,8-Hexachlorodibenzodioxin
def: "An exposure to 1,2,3,6,7,8-Hexachlorodibenzodioxin." []
synonym: "1,2,3,6,7,8-Hexachlorodibenzodioxin exposure" EXACT []
is_a: ECTO:9001625 ! exposure to polychlorinated dibenzodioxine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81503 ! has exposure stimulus 1,2,3,6,7,8-Hexachlorodibenzodioxin
relationship: RO:0002309 CHEBI:81503 ! has exposure stimulus 1,2,3,6,7,8-Hexachlorodibenzodioxin

[Term]
id: ECTO:9001329
name: exposure to 1,2,3,4,6,7,8-Heptachlorodibenzodioxin
def: "An exposure to 1,2,3,4,6,7,8-Heptachlorodibenzodioxin." []
synonym: "1,2,3,4,6,7,8-Heptachlorodibenzodioxin exposure" EXACT []
is_a: ECTO:9001625 ! exposure to polychlorinated dibenzodioxine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81505 ! has exposure stimulus 1,2,3,4,6,7,8-Heptachlorodibenzodioxin
relationship: RO:0002309 CHEBI:81505 ! has exposure stimulus 1,2,3,4,6,7,8-Heptachlorodibenzodioxin

[Term]
id: ECTO:9001330
name: exposure to 2,3,7,8-Tetrachlorodibenzofuran
def: "An exposure to 2,3,7,8-Tetrachlorodibenzofuran." []
synonym: "2,3,7,8-Tetrachlorodibenzofuran exposure" EXACT []
is_a: ECTO:9001539 ! exposure to polychlorinated dibenzofuran
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81506 ! has exposure stimulus 2,3,7,8-Tetrachlorodibenzofuran
relationship: RO:0002309 CHEBI:81506 ! has exposure stimulus 2,3,7,8-Tetrachlorodibenzofuran

[Term]
id: ECTO:9001331
name: exposure to 1,2,3,4,6,7,8-Heptachlorodibenzofuran
def: "An exposure to 1,2,3,4,6,7,8-Heptachlorodibenzofuran." []
synonym: "1,2,3,4,6,7,8-Heptachlorodibenzofuran exposure" EXACT []
is_a: ECTO:9001539 ! exposure to polychlorinated dibenzofuran
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81513 ! has exposure stimulus 1,2,3,4,6,7,8-Heptachlorodibenzofuran
relationship: RO:0002309 CHEBI:81513 ! has exposure stimulus 1,2,3,4,6,7,8-Heptachlorodibenzofuran

[Term]
id: ECTO:9001332
name: exposure to squalene
def: "An exposure to squalene." []
synonym: "squalene exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15440 ! has exposure stimulus squalene
relationship: RO:0002309 CHEBI:15440 ! has exposure stimulus squalene

[Term]
id: ECTO:9001333
name: exposure to inulin
def: "An exposure to inulin." []
synonym: "inulin exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15443 ! has exposure stimulus inulin
relationship: RO:0002309 CHEBI:15443 ! has exposure stimulus inulin

[Term]
id: ECTO:9001334
name: exposure to primary alcohol
def: "An exposure to primary alcohol." []
synonym: "primary alcohol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15734 ! has exposure stimulus primary alcohol
relationship: RO:0002309 CHEBI:15734 ! has exposure stimulus primary alcohol

[Term]
id: ECTO:9001335
name: exposure to lycopene
def: "An exposure to lycopene." []
synonym: "lycopene exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15948 ! has exposure stimulus lycopene
relationship: RO:0002309 CHEBI:15948 ! has exposure stimulus lycopene

[Term]
id: ECTO:9001336
name: exposure to quercetin
def: "An exposure to quercetin." []
synonym: "quercetin exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16243 ! has exposure stimulus quercetin
relationship: RO:0002309 CHEBI:16243 ! has exposure stimulus quercetin

[Term]
id: ECTO:9001337
name: exposure to 1H-pyrazole
def: "An exposure to 1H-pyrazole." []
synonym: "1H-pyrazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17241 ! has exposure stimulus 1H-pyrazole
relationship: RO:0002309 CHEBI:17241 ! has exposure stimulus 1H-pyrazole

[Term]
id: ECTO:9001338
name: exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
def: "An exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine." []
synonym: "1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17963 ! has exposure stimulus 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
relationship: RO:0002309 CHEBI:17963 ! has exposure stimulus 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

[Term]
id: ECTO:9001339
name: exposure to polysaccharide
def: "An exposure to polysaccharide." []
synonym: "polysaccharide exposure" EXACT []
is_a: ECTO:9000162 ! exposure to carbohydrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18154 ! has exposure stimulus polysaccharide
relationship: RO:0002309 CHEBI:18154 ! has exposure stimulus polysaccharide

[Term]
id: ECTO:9001340
name: exposure to N-methyl-N'-nitro-N-nitrosoguanidine
def: "An exposure to N-methyl-N'-nitro-N-nitrosoguanidine." []
synonym: "N-methyl-N'-nitro-N-nitrosoguanidine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:21759 ! has exposure stimulus N-methyl-N'-nitro-N-nitrosoguanidine
relationship: RO:0002309 CHEBI:21759 ! has exposure stimulus N-methyl-N'-nitro-N-nitrosoguanidine

[Term]
id: ECTO:9001341
name: exposure to alpha-tocopherol
def: "An exposure to alpha-tocopherol." []
synonym: "alpha-tocopherol exposure" EXACT []
is_a: ECTO:9000136 ! exposure to tocopherol
is_a: ECTO:9000224 ! exposure to vitamin E
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22470 ! has exposure stimulus alpha-tocopherol
relationship: RO:0002309 CHEBI:22470 ! has exposure stimulus alpha-tocopherol

[Term]
id: ECTO:9001342
name: exposure to N-ethyl-N-nitrosourea
def: "An exposure to N-ethyl-N-nitrosourea." []
synonym: "N-ethyl-N-nitrosourea exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23995 ! has exposure stimulus N-ethyl-N-nitrosourea
relationship: RO:0002309 CHEBI:23995 ! has exposure stimulus N-ethyl-N-nitrosourea

[Term]
id: ECTO:9001343
name: exposure to 7,12-dimethyltetraphene
def: "An exposure to 7,12-dimethyltetraphene." []
synonym: "7,12-dimethyltetraphene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:254496 ! has exposure stimulus 7,12-dimethyltetraphene
relationship: RO:0002309 CHEBI:254496 ! has exposure stimulus 7,12-dimethyltetraphene

[Term]
id: ECTO:9001344
name: exposure to alendronic acid
def: "An exposure to alendronic acid." []
synonym: "alendronic acid exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2567 ! has exposure stimulus alendronic acid
relationship: RO:0002309 CHEBI:2567 ! has exposure stimulus alendronic acid

[Term]
id: ECTO:9001345
name: exposure to phosphate
def: "An exposure to phosphate." []
synonym: "phosphate exposure" EXACT []
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26020 ! has exposure stimulus phosphate
relationship: RO:0002309 CHEBI:26020 ! has exposure stimulus phosphate

[Term]
id: ECTO:9001346
name: exposure to retinoid
def: "An exposure to retinoid." []
synonym: "retinoid exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26537 ! has exposure stimulus retinoid
relationship: RO:0002309 CHEBI:26537 ! has exposure stimulus retinoid

[Term]
id: ECTO:9001347
name: exposure to sodium chloride
def: "An exposure to sodium chloride." []
synonym: "sodium chloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26710 ! has exposure stimulus sodium chloride
relationship: RO:0002309 CHEBI:26710 ! has exposure stimulus sodium chloride

[Term]
id: ECTO:9001348
name: exposure to ceftriaxone
def: "An exposure to ceftriaxone." []
synonym: "ceftriaxone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29007 ! has exposure stimulus ceftriaxone
relationship: RO:0002309 CHEBI:29007 ! has exposure stimulus ceftriaxone

[Term]
id: ECTO:9001349
name: exposure to sodium nitroprusside
def: "An exposure to sodium nitroprusside." []
synonym: "sodium nitroprusside exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29321 ! has exposure stimulus sodium nitroprusside
relationship: RO:0002309 CHEBI:29321 ! has exposure stimulus sodium nitroprusside

[Term]
id: ECTO:9001350
name: exposure to potassium chloride
def: "An exposure to potassium chloride." []
synonym: "potassium chloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32588 ! has exposure stimulus potassium chloride
relationship: RO:0002309 CHEBI:32588 ! has exposure stimulus potassium chloride

[Term]
id: ECTO:9001351
name: exposure to technetium-99
def: "An exposure to technetium-99." []
synonym: "technetium-99 exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33371 ! has exposure stimulus technetium-99
relationship: RO:0002309 CHEBI:33371 ! has exposure stimulus technetium-99

[Term]
id: ECTO:9001352
name: exposure to captopril
def: "An exposure to captopril." []
synonym: "captopril exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3380 ! has exposure stimulus captopril
relationship: RO:0002309 CHEBI:3380 ! has exposure stimulus captopril

[Term]
id: ECTO:9001353
name: exposure to phenols
def: "An exposure to phenols." []
synonym: "phenols exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33853 ! has exposure stimulus phenols
relationship: RO:0002309 CHEBI:33853 ! has exposure stimulus phenols

[Term]
id: ECTO:9001354
name: exposure to carrageenan
def: "An exposure to carrageenan." []
synonym: "carrageenan exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3435 ! has exposure stimulus carrageenan
relationship: RO:0002309 CHEBI:3435 ! has exposure stimulus carrageenan

[Term]
id: ECTO:9001355
name: exposure to 4-octylphenol
def: "An exposure to 4-octylphenol." []
synonym: "4-octylphenol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34432 ! has exposure stimulus 4-octylphenol
relationship: RO:0002309 CHEBI:34432 ! has exposure stimulus 4-octylphenol

[Term]
id: ECTO:9001356
name: exposure to pentolinium ion
def: "An exposure to pentolinium ion." []
synonym: "pentolinium ion exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:347401 ! has exposure stimulus pentolinium ion
relationship: RO:0002309 CHEBI:347401 ! has exposure stimulus pentolinium ion

[Term]
id: ECTO:9001357
name: exposure to ruthenium red
def: "An exposure to ruthenium red." []
synonym: "ruthenium red exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34956 ! has exposure stimulus ruthenium red
relationship: RO:0002309 CHEBI:34956 ! has exposure stimulus ruthenium red

[Term]
id: ECTO:9001359
name: exposure to sulfonamide
def: "An exposure to sulfonamide." []
synonym: "sulfonamide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35358 ! has exposure stimulus sulfonamide
relationship: RO:0002309 CHEBI:35358 ! has exposure stimulus sulfonamide

[Term]
id: ECTO:9001360
name: exposure to benfotiamine
def: "An exposure to benfotiamine." []
synonym: "benfotiamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41039 ! has exposure stimulus benfotiamine
relationship: RO:0002309 CHEBI:41039 ! has exposure stimulus benfotiamine

[Term]
id: ECTO:9001361
name: exposure to diethylstilbestrol
def: "An exposure to diethylstilbestrol." []
synonym: "diethylstilbestrol exposure" EXACT []
is_a: ECTO:9000251 ! exposure to stilbenoid
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41922 ! has exposure stimulus diethylstilbestrol
relationship: RO:0002309 CHEBI:41922 ! has exposure stimulus diethylstilbestrol

[Term]
id: ECTO:9001362
name: exposure to acepromazine
def: "An exposure to acepromazine." []
synonym: "acepromazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44932 ! has exposure stimulus acepromazine
relationship: RO:0002309 CHEBI:44932 ! has exposure stimulus acepromazine

[Term]
id: ECTO:9001363
name: exposure to dihydrocapsaicin
def: "An exposure to dihydrocapsaicin." []
synonym: "dihydrocapsaicin exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46932 ! has exposure stimulus dihydrocapsaicin
relationship: RO:0002309 CHEBI:46932 ! has exposure stimulus dihydrocapsaicin

[Term]
id: ECTO:9001364
name: exposure to 5-bromo-2'-deoxyuridine
def: "An exposure to 5-bromo-2'-deoxyuridine." []
synonym: "5-bromo-2'-deoxyuridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:472552 ! has exposure stimulus 5-bromo-2'-deoxyuridine
relationship: RO:0002309 CHEBI:472552 ! has exposure stimulus 5-bromo-2'-deoxyuridine

[Term]
id: ECTO:9001365
name: exposure to 4-methyl-2-oxopentanoic acid
def: "An exposure to 4-methyl-2-oxopentanoic acid." []
synonym: "4-methyl-2-oxopentanoic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48430 ! has exposure stimulus 4-methyl-2-oxopentanoic acid
relationship: RO:0002309 CHEBI:48430 ! has exposure stimulus 4-methyl-2-oxopentanoic acid

[Term]
id: ECTO:9001366
name: exposure to angiotensin II
def: "An exposure to angiotensin II." []
synonym: "angiotensin II exposure" EXACT []
is_a: ECTO:9000517 ! exposure to angiotensin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48432 ! has exposure stimulus angiotensin II
relationship: RO:0002309 CHEBI:48432 ! has exposure stimulus angiotensin II

[Term]
id: ECTO:9001367
name: exposure to lithium chloride
def: "An exposure to lithium chloride." []
synonym: "lithium chloride exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48607 ! has exposure stimulus lithium chloride
relationship: RO:0002309 CHEBI:48607 ! has exposure stimulus lithium chloride

[Term]
id: ECTO:9001368
name: exposure to naringenin
def: "An exposure to naringenin." []
synonym: "naringenin exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50202 ! has exposure stimulus naringenin
relationship: RO:0002309 CHEBI:50202 ! has exposure stimulus naringenin

[Term]
id: ECTO:9001369
name: exposure to titanium dioxide nanoparticle
def: "An exposure to titanium dioxide nanoparticle." []
synonym: "titanium dioxide nanoparticle exposure" EXACT []
is_a: ECTO:9001510 ! exposure to titanium dioxide
is_a: ECTO:9002233 ! exposure to nanoparticle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51050 ! has exposure stimulus titanium dioxide nanoparticle
relationship: RO:0002309 CHEBI:51050 ! has exposure stimulus titanium dioxide nanoparticle

[Term]
id: ECTO:9001370
name: exposure to pristane
def: "An exposure to pristane." []
synonym: "pristane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53181 ! has exposure stimulus pristane
relationship: RO:0002309 CHEBI:53181 ! has exposure stimulus pristane

[Term]
id: ECTO:9001371
name: exposure to glyburide
def: "An exposure to glyburide." []
synonym: "glyburide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5441 ! has exposure stimulus glyburide
relationship: RO:0002309 CHEBI:5441 ! has exposure stimulus glyburide

[Term]
id: ECTO:9001372
name: exposure to pentolinium tartrate
def: "An exposure to pentolinium tartrate." []
synonym: "pentolinium tartrate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:55326 ! has exposure stimulus pentolinium tartrate
relationship: RO:0002309 CHEBI:55326 ! has exposure stimulus pentolinium tartrate

[Term]
id: ECTO:9001373
name: exposure to guanethidine
def: "An exposure to guanethidine." []
synonym: "guanethidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5557 ! has exposure stimulus guanethidine
relationship: RO:0002309 CHEBI:5557 ! has exposure stimulus guanethidine

[Term]
id: ECTO:9001374
name: exposure to isotretinoin
def: "An exposure to isotretinoin." []
synonym: "isotretinoin exposure" EXACT []
is_a: ECTO:9000216 ! exposure to retinoic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6067 ! has exposure stimulus isotretinoin
relationship: RO:0002309 CHEBI:6067 ! has exposure stimulus isotretinoin

[Term]
id: ECTO:9001375
name: exposure to isoprenaline
def: "An exposure to isoprenaline." []
synonym: "isoprenaline exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64317 ! has exposure stimulus isoprenaline
relationship: RO:0002309 CHEBI:64317 ! has exposure stimulus isoprenaline

[Term]
id: ECTO:9001376
name: exposure to losartan
def: "An exposure to losartan." []
synonym: "losartan exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6541 ! has exposure stimulus losartan
relationship: RO:0002309 CHEBI:6541 ! has exposure stimulus losartan

[Term]
id: ECTO:9001377
name: exposure to methacholine
def: "An exposure to methacholine." []
synonym: "methacholine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000304 ! exposure to ammonium ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6804 ! has exposure stimulus methacholine
relationship: RO:0002309 CHEBI:6804 ! has exposure stimulus methacholine

[Term]
id: ECTO:9001378
name: exposure to methylene blue
def: "An exposure to methylene blue." []
synonym: "methylene blue exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6872 ! has exposure stimulus methylene blue
relationship: RO:0002309 CHEBI:6872 ! has exposure stimulus methylene blue

[Term]
id: ECTO:9001379
name: exposure to 1,2-dimethylhydrazine
def: "An exposure to 1,2-dimethylhydrazine." []
synonym: "1,2-dimethylhydrazine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73755 ! has exposure stimulus 1,2-dimethylhydrazine
relationship: RO:0002309 CHEBI:73755 ! has exposure stimulus 1,2-dimethylhydrazine

[Term]
id: ECTO:9001380
name: exposure to chrysin
def: "An exposure to chrysin." []
synonym: "chrysin exposure" EXACT []
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75095 ! has exposure stimulus chrysin
relationship: RO:0002309 CHEBI:75095 ! has exposure stimulus chrysin

[Term]
id: ECTO:9001381
name: exposure to 3-methyl-4'-dimethylaminoazobenzene
def: "An exposure to 3-methyl-4'-dimethylaminoazobenzene." []
synonym: "3-methyl-4'-dimethylaminoazobenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76329 ! has exposure stimulus 3-methyl-4'-dimethylaminoazobenzene
relationship: RO:0002309 CHEBI:76329 ! has exposure stimulus 3-methyl-4'-dimethylaminoazobenzene

[Term]
id: ECTO:9001382
name: exposure to oxidopamine
def: "An exposure to oxidopamine." []
synonym: "oxidopamine exposure" EXACT []
is_a: ECTO:9000319 ! exposure to catecholamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78741 ! has exposure stimulus oxidopamine
relationship: RO:0002309 CHEBI:78741 ! has exposure stimulus oxidopamine

[Term]
id: ECTO:9001383
name: exposure to phenylephrine
def: "An exposure to phenylephrine." []
synonym: "phenylephrine exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8093 ! has exposure stimulus phenylephrine
relationship: RO:0002309 CHEBI:8093 ! has exposure stimulus phenylephrine

[Term]
id: ECTO:9001384
name: exposure to streptozocin
def: "An exposure to streptozocin." []
synonym: "streptozocin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9288 ! has exposure stimulus streptozocin
relationship: RO:0002309 CHEBI:9288 ! has exposure stimulus streptozocin

[Term]
id: ECTO:9001385
name: exposure to trimethaphan camsylate
def: "An exposure to trimethaphan camsylate." []
synonym: "trimethaphan camsylate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9729 ! has exposure stimulus trimethaphan camsylate
relationship: RO:0002309 CHEBI:9729 ! has exposure stimulus trimethaphan camsylate

[Term]
id: ECTO:9001386
name: exposure to heroin
def: "An exposure to heroin." []
synonym: "heroin exposure" EXACT []
is_a: ECTO:9000200 ! exposure to isoquinoline alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27808 ! has exposure stimulus heroin
relationship: RO:0002309 CHEBI:27808 ! has exposure stimulus heroin

[Term]
id: ECTO:9001387
name: obsolete triclosan exposure
is_obsolete: true
replaced_by: ECTO:9000078

[Term]
id: ECTO:9001388
name: exposure to organotin compound
def: "An exposure to organotin compound." []
synonym: "organotin compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000952 ! exposure to tin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25717 ! has exposure stimulus organotin compound
relationship: RO:0002309 CHEBI:25717 ! has exposure stimulus organotin compound

[Term]
id: ECTO:9001389
name: exposure to organotin acaricide
def: "An exposure to organotin acaricide." []
synonym: "organotin acaricide exposure" EXACT []
is_a: ECTO:9001388 ! exposure to organotin compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39292 ! has exposure stimulus organotin acaricide
relationship: RO:0002309 CHEBI:39292 ! has exposure stimulus organotin acaricide

[Term]
id: ECTO:9001391
name: exposure to acetic anhydride
def: "An exposure to acetic anhydride." []
synonym: "acetic anhydride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36610 ! has exposure stimulus acetic anhydride
relationship: RO:0002309 CHEBI:36610 ! has exposure stimulus acetic anhydride

[Term]
id: ECTO:9001393
name: exposure to acetylene
def: "An exposure to acetylene." []
synonym: "acetylene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27518 ! has exposure stimulus acetylene
relationship: RO:0002309 CHEBI:27518 ! has exposure stimulus acetylene

[Term]
id: ECTO:9001394
name: obsolete acetylsalicylic acid exposure
is_obsolete: true
replaced_by: ECTO:9000008

[Term]
id: ECTO:9001395
name: exposure to ammonium chloride
def: "An exposure to ammonium chloride." []
synonym: "ammonium chloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9002218 ! exposure to ammonium salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31206 ! has exposure stimulus ammonium chloride
relationship: RO:0002309 CHEBI:31206 ! has exposure stimulus ammonium chloride

[Term]
id: ECTO:9001396
name: exposure to arsane
def: "An exposure to arsane." []
synonym: "arsane exposure" EXACT []
is_a: ECTO:9000032 ! exposure to arsenic
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47217 ! has exposure stimulus arsane
relationship: RO:0002309 CHEBI:47217 ! has exposure stimulus arsane

[Term]
id: ECTO:9001397
name: exposure to thiophenol
def: "An exposure to thiophenol." []
synonym: "thiophenol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48498 ! has exposure stimulus thiophenol
relationship: RO:0002309 CHEBI:48498 ! has exposure stimulus thiophenol

[Term]
id: ECTO:9001398
name: exposure to diboron trioxide
def: "An exposure to diboron trioxide." []
synonym: "diboron trioxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000173 ! exposure to boron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30163 ! has exposure stimulus diboron trioxide
relationship: RO:0002309 CHEBI:30163 ! has exposure stimulus diboron trioxide

[Term]
id: ECTO:9001399
name: exposure to butane
def: "An exposure to butane." []
synonym: "butane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37808 ! has exposure stimulus butane
relationship: RO:0002309 CHEBI:37808 ! has exposure stimulus butane

[Term]
id: ECTO:9001400
name: exposure to butan-2-one
def: "An exposure to butan-2-one." []
synonym: "butan-2-one exposure" EXACT []
is_a: ECTO:9000083 ! exposure to butanone
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28398 ! has exposure stimulus butan-2-one
relationship: RO:0002309 CHEBI:28398 ! has exposure stimulus butan-2-one

[Term]
id: ECTO:9001401
name: exposure to butyl acetate
def: "An exposure to butyl acetate." []
synonym: "butyl acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31328 ! has exposure stimulus butyl acetate
relationship: RO:0002309 CHEBI:31328 ! has exposure stimulus butyl acetate

[Term]
id: ECTO:9001402
name: exposure to butan-1-amine
def: "An exposure to butan-1-amine." []
synonym: "butan-1-amine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43799 ! has exposure stimulus butan-1-amine
relationship: RO:0002309 CHEBI:43799 ! has exposure stimulus butan-1-amine

[Term]
id: ECTO:9001403
name: exposure to butyronitrile
def: "An exposure to butyronitrile." []
synonym: "butyronitrile exposure" EXACT []
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51937 ! has exposure stimulus butyronitrile
relationship: RO:0002309 CHEBI:51937 ! has exposure stimulus butyronitrile

[Term]
id: ECTO:9001404
name: exposure to calcium carbonate
def: "An exposure to calcium carbonate." []
synonym: "calcium carbonate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3311 ! has exposure stimulus calcium carbonate
relationship: RO:0002309 CHEBI:3311 ! has exposure stimulus calcium carbonate

[Term]
id: ECTO:9001405
name: exposure to calcium dihydroxide
def: "An exposure to calcium dihydroxide." []
synonym: "calcium dihydroxide exposure" EXACT []
is_a: ECTO:9000024 ! exposure to calcium hydroxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31341 ! has exposure stimulus calcium dihydroxide
relationship: RO:0002309 CHEBI:31341 ! has exposure stimulus calcium dihydroxide

[Term]
id: ECTO:9001406
name: exposure to calcium sulfate
def: "An exposure to calcium sulfate." []
synonym: "calcium sulfate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31346 ! has exposure stimulus calcium sulfate
relationship: RO:0002309 CHEBI:31346 ! has exposure stimulus calcium sulfate

[Term]
id: ECTO:9001407
name: exposure to camphor
def: "An exposure to camphor." []
synonym: "camphor exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36773 ! has exposure stimulus camphor
relationship: RO:0002309 CHEBI:36773 ! has exposure stimulus camphor

[Term]
id: ECTO:9001408
name: exposure to epsilon-caprolactam
def: "An exposure to epsilon-caprolactam." []
synonym: "epsilon-caprolactam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28579 ! has exposure stimulus epsilon-caprolactam
relationship: RO:0002309 CHEBI:28579 ! has exposure stimulus epsilon-caprolactam

[Term]
id: ECTO:9001409
name: exposure to captafol
def: "An exposure to captafol." []
synonym: "captafol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81938 ! has exposure stimulus captafol
relationship: RO:0002309 CHEBI:81938 ! has exposure stimulus captafol

[Term]
id: ECTO:9001410
name: exposure to tetrabromomethane
def: "An exposure to tetrabromomethane." []
synonym: "tetrabromomethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47875 ! has exposure stimulus tetrabromomethane
relationship: RO:0002309 CHEBI:47875 ! has exposure stimulus tetrabromomethane

[Term]
id: ECTO:9001411
name: exposure to caesium hydroxide
def: "An exposure to caesium hydroxide." []
synonym: "caesium hydroxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000184 ! exposure to caesium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33988 ! has exposure stimulus caesium hydroxide
relationship: RO:0002309 CHEBI:33988 ! has exposure stimulus caesium hydroxide

[Term]
id: ECTO:9001412
name: exposure to dioxidochlorine(.)
def: "An exposure to dioxidochlorine(.)." []
synonym: "dioxidochlorine(.) exposure" EXACT []
is_a: ECTO:9001022 ! exposure to chlorine dioxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29415 ! has exposure stimulus dioxidochlorine(.)
relationship: RO:0002309 CHEBI:29415 ! has exposure stimulus dioxidochlorine(.)

[Term]
id: ECTO:9001413
name: exposure to trifluorochlorine
def: "An exposure to trifluorochlorine." []
synonym: "trifluorochlorine exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30123 ! has exposure stimulus trifluorochlorine
relationship: RO:0002309 CHEBI:30123 ! has exposure stimulus trifluorochlorine

[Term]
id: ECTO:9001414
name: exposure to bromochloromethane
def: "An exposure to bromochloromethane." []
synonym: "bromochloromethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17194 ! has exposure stimulus bromochloromethane
relationship: RO:0002309 CHEBI:17194 ! has exposure stimulus bromochloromethane

[Term]
id: ECTO:9001415
name: exposure to chromic acid
def: "An exposure to chromic acid." []
synonym: "chromic acid exposure" EXACT []
is_a: ECTO:9000037 ! exposure to chromium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33143 ! has exposure stimulus chromic acid
relationship: RO:0002309 CHEBI:33143 ! has exposure stimulus chromic acid

[Term]
id: ECTO:9001416
name: exposure to dichromium trioxide
def: "An exposure to dichromium trioxide." []
synonym: "dichromium trioxide exposure" EXACT []
is_a: ECTO:9000037 ! exposure to chromium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48242 ! has exposure stimulus dichromium trioxide
relationship: RO:0002309 CHEBI:48242 ! has exposure stimulus dichromium trioxide

[Term]
id: ECTO:9001417
name: exposure to chromyl dichloride
def: "An exposure to chromyl dichloride." []
synonym: "chromyl dichloride exposure" EXACT []
is_a: ECTO:9000037 ! exposure to chromium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33038 ! has exposure stimulus chromyl dichloride
relationship: RO:0002309 CHEBI:33038 ! has exposure stimulus chromyl dichloride

[Term]
id: ECTO:9001418
name: exposure to cumene
def: "An exposure to cumene." []
synonym: "cumene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34656 ! has exposure stimulus cumene
relationship: RO:0002309 CHEBI:34656 ! has exposure stimulus cumene

[Term]
id: ECTO:9001419
name: exposure to cyanamide
def: "An exposure to cyanamide." []
synonym: "cyanamide exposure" EXACT []
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16698 ! has exposure stimulus cyanamide
relationship: RO:0002309 CHEBI:16698 ! has exposure stimulus cyanamide

[Term]
id: ECTO:9001420
name: exposure to oxalonitrile
def: "An exposure to oxalonitrile." []
synonym: "oxalonitrile exposure" EXACT []
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29308 ! has exposure stimulus oxalonitrile
relationship: RO:0002309 CHEBI:29308 ! has exposure stimulus oxalonitrile

[Term]
id: ECTO:9001421
name: exposure to cyclohexanone
def: "An exposure to cyclohexanone." []
synonym: "cyclohexanone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17854 ! has exposure stimulus cyclohexanone
relationship: RO:0002309 CHEBI:17854 ! has exposure stimulus cyclohexanone

[Term]
id: ECTO:9001422
name: exposure to cyclohexene
def: "An exposure to cyclohexene." []
synonym: "cyclohexene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36404 ! has exposure stimulus cyclohexene
relationship: RO:0002309 CHEBI:36404 ! has exposure stimulus cyclohexene

[Term]
id: ECTO:9001423
name: exposure to cyclohexylamine
def: "An exposure to cyclohexylamine." []
synonym: "cyclohexylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15773 ! has exposure stimulus cyclohexylamine
relationship: RO:0002309 CHEBI:15773 ! has exposure stimulus cyclohexylamine

[Term]
id: ECTO:9001424
name: exposure to 1,3,5-trinitro-1,3,5-triazinane
def: "An exposure to 1,3,5-trinitro-1,3,5-triazinane." []
synonym: "1,3,5-trinitro-1,3,5-triazinane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24556 ! has exposure stimulus 1,3,5-trinitro-1,3,5-triazinane
relationship: RO:0002309 CHEBI:24556 ! has exposure stimulus 1,3,5-trinitro-1,3,5-triazinane

[Term]
id: ECTO:9001425
name: exposure to cyclopentadiene
def: "An exposure to cyclopentadiene." []
synonym: "cyclopentadiene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30664 ! has exposure stimulus cyclopentadiene
relationship: RO:0002309 CHEBI:30664 ! has exposure stimulus cyclopentadiene

[Term]
id: ECTO:9001426
name: exposure to cyclopentane
def: "An exposure to cyclopentane." []
synonym: "cyclopentane exposure" EXACT []
is_a: ECTO:9000199 ! exposure to cycloalkane
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23492 ! has exposure stimulus cyclopentane
relationship: RO:0002309 CHEBI:23492 ! has exposure stimulus cyclopentane

[Term]
id: ECTO:9001427
name: exposure to diacetone alcohol
def: "An exposure to diacetone alcohol." []
synonym: "diacetone alcohol exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:55381 ! has exposure stimulus diacetone alcohol
relationship: RO:0002309 CHEBI:55381 ! has exposure stimulus diacetone alcohol

[Term]
id: ECTO:9001428
name: exposure to diborane(6)
def: "An exposure to diborane(6)." []
synonym: "diborane(6) exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000173 ! exposure to boron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33590 ! has exposure stimulus diborane(6)
relationship: RO:0002309 CHEBI:33590 ! has exposure stimulus diborane(6)

[Term]
id: ECTO:9001429
name: exposure to ferrocene
def: "An exposure to ferrocene." []
synonym: "ferrocene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000087 ! exposure to iron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30672 ! has exposure stimulus ferrocene
relationship: RO:0002309 CHEBI:30672 ! has exposure stimulus ferrocene

[Term]
id: ECTO:9001430
name: exposure to dieldrin
def: "An exposure to dieldrin." []
synonym: "dieldrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001534 ! exposure to organochlorine insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34696 ! has exposure stimulus dieldrin
relationship: RO:0002309 CHEBI:34696 ! has exposure stimulus dieldrin

[Term]
id: ECTO:9001431
name: exposure to 2-diethylaminoethanol
def: "An exposure to 2-diethylaminoethanol." []
synonym: "2-diethylaminoethanol exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52153 ! has exposure stimulus 2-diethylaminoethanol
relationship: RO:0002309 CHEBI:52153 ! has exposure stimulus 2-diethylaminoethanol

[Term]
id: ECTO:9001432
name: exposure to diethylenetriamine
def: "An exposure to diethylenetriamine." []
synonym: "diethylenetriamine exposure" EXACT []
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30629 ! has exposure stimulus diethylenetriamine
relationship: RO:0002309 CHEBI:30629 ! has exposure stimulus diethylenetriamine

[Term]
id: ECTO:9001433
name: exposure to diethyl phthalate
def: "An exposure to diethyl phthalate." []
synonym: "diethyl phthalate exposure" EXACT []
is_a: ECTO:9000906 ! exposure to phthalate ester
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34698 ! has exposure stimulus diethyl phthalate
relationship: RO:0002309 CHEBI:34698 ! has exposure stimulus diethyl phthalate

[Term]
id: ECTO:9001434
name: exposure to disulfiram
def: "An exposure to disulfiram." []
synonym: "disulfiram exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4659 ! has exposure stimulus disulfiram
relationship: RO:0002309 CHEBI:4659 ! has exposure stimulus disulfiram

[Term]
id: ECTO:9001435
name: exposure to disulfoton
def: "An exposure to disulfoton." []
synonym: "disulfoton exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38661 ! has exposure stimulus disulfoton
relationship: RO:0002309 CHEBI:38661 ! has exposure stimulus disulfoton

[Term]
id: ECTO:9001436
name: exposure to 2,6-di-tert-butyl-4-methylphenol
def: "An exposure to 2,6-di-tert-butyl-4-methylphenol." []
synonym: "2,6-di-tert-butyl-4-methylphenol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34247 ! has exposure stimulus 2,6-di-tert-butyl-4-methylphenol
relationship: RO:0002309 CHEBI:34247 ! has exposure stimulus 2,6-di-tert-butyl-4-methylphenol

[Term]
id: ECTO:9001437
name: exposure to enflurane
def: "An exposure to enflurane." []
synonym: "enflurane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4792 ! has exposure stimulus enflurane
relationship: RO:0002309 CHEBI:4792 ! has exposure stimulus enflurane

[Term]
id: ECTO:9001438
name: exposure to ethanolamine
def: "An exposure to ethanolamine." []
synonym: "ethanolamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16000 ! has exposure stimulus ethanolamine
relationship: RO:0002309 CHEBI:16000 ! has exposure stimulus ethanolamine

[Term]
id: ECTO:9001439
name: exposure to ethyl acetate
def: "An exposure to ethyl acetate." []
synonym: "ethyl acetate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27750 ! has exposure stimulus ethyl acetate
relationship: RO:0002309 CHEBI:27750 ! has exposure stimulus ethyl acetate

[Term]
id: ECTO:9001440
name: exposure to ethylamine
def: "An exposure to ethylamine." []
synonym: "ethylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15862 ! has exposure stimulus ethylamine
relationship: RO:0002309 CHEBI:15862 ! has exposure stimulus ethylamine

[Term]
id: ECTO:9001441
name: exposure to 2-chloroethanol
def: "An exposure to 2-chloroethanol." []
synonym: "2-chloroethanol exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28200 ! has exposure stimulus 2-chloroethanol
relationship: RO:0002309 CHEBI:28200 ! has exposure stimulus 2-chloroethanol

[Term]
id: ECTO:9001442
name: exposure to ethylenediamine
def: "An exposure to ethylenediamine." []
synonym: "ethylenediamine exposure" EXACT []
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30347 ! has exposure stimulus ethylenediamine
relationship: RO:0002309 CHEBI:30347 ! has exposure stimulus ethylenediamine

[Term]
id: ECTO:9001443
name: exposure to diethyl ether
def: "An exposure to diethyl ether." []
synonym: "diethyl ether exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35702 ! has exposure stimulus diethyl ether
relationship: RO:0002309 CHEBI:35702 ! has exposure stimulus diethyl ether

[Term]
id: ECTO:9001444
name: exposure to ethyl formate
def: "An exposure to ethyl formate." []
synonym: "ethyl formate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52342 ! has exposure stimulus ethyl formate
relationship: RO:0002309 CHEBI:52342 ! has exposure stimulus ethyl formate

[Term]
id: ECTO:9001445
name: exposure to fenamiphos
def: "An exposure to fenamiphos." []
synonym: "fenamiphos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38680 ! has exposure stimulus fenamiphos
relationship: RO:0002309 CHEBI:38680 ! has exposure stimulus fenamiphos

[Term]
id: ECTO:9001446
name: exposure to formimidic acid
def: "An exposure to formimidic acid." []
synonym: "formimidic acid exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48431 ! has exposure stimulus formimidic acid
relationship: RO:0002309 CHEBI:48431 ! has exposure stimulus formimidic acid

[Term]
id: ECTO:9001447
name: exposure to furfuryl alcohol
def: "An exposure to furfuryl alcohol." []
synonym: "furfuryl alcohol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:207496 ! has exposure stimulus furfuryl alcohol
relationship: RO:0002309 CHEBI:207496 ! has exposure stimulus furfuryl alcohol

[Term]
id: ECTO:9001448
name: exposure to germane
def: "An exposure to germane." []
synonym: "germane exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30443 ! has exposure stimulus germane
relationship: RO:0002309 CHEBI:30443 ! has exposure stimulus germane

[Term]
id: ECTO:9001449
name: exposure to alditol
def: "An exposure to alditol." []
synonym: "alditol exposure" EXACT []
is_a: ECTO:9000162 ! exposure to carbohydrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17522 ! has exposure stimulus alditol
relationship: RO:0002309 CHEBI:17522 ! has exposure stimulus alditol

[Term]
id: ECTO:9001450
name: exposure to halothane
def: "An exposure to halothane." []
synonym: "halothane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5615 ! has exposure stimulus halothane
relationship: RO:0002309 CHEBI:5615 ! has exposure stimulus halothane

[Term]
id: ECTO:9001452
name: exposure to hexafluoroacetone
def: "An exposure to hexafluoroacetone." []
synonym: "hexafluoroacetone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39429 ! has exposure stimulus hexafluoroacetone
relationship: RO:0002309 CHEBI:39429 ! has exposure stimulus hexafluoroacetone

[Term]
id: ECTO:9001453
name: exposure to hydrogen bromide
def: "An exposure to hydrogen bromide." []
synonym: "hydrogen bromide exposure" EXACT []
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47266 ! has exposure stimulus hydrogen bromide
relationship: RO:0002309 CHEBI:47266 ! has exposure stimulus hydrogen bromide

[Term]
id: ECTO:9001454
name: exposure to 1H-indene
def: "An exposure to 1H-indene." []
synonym: "1H-indene exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41921 ! has exposure stimulus 1H-indene
relationship: RO:0002309 CHEBI:41921 ! has exposure stimulus 1H-indene

[Term]
id: ECTO:9001455
name: exposure to iodoform
def: "An exposure to iodoform." []
synonym: "iodoform exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37758 ! has exposure stimulus iodoform
relationship: RO:0002309 CHEBI:37758 ! has exposure stimulus iodoform

[Term]
id: ECTO:9001456
name: exposure to ferric oxide
def: "An exposure to ferric oxide." []
synonym: "ferric oxide exposure" EXACT []
is_a: ECTO:9002623 ! exposure to iron oxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50819 ! has exposure stimulus ferric oxide
relationship: RO:0002309 CHEBI:50819 ! has exposure stimulus ferric oxide

[Term]
id: ECTO:9001457
name: exposure to iron(2+) sulfate (anhydrous)
def: "An exposure to iron(2+) sulfate (anhydrous)." []
synonym: "iron(2+) sulfate (anhydrous) exposure" EXACT []
is_a: ECTO:9000087 ! exposure to iron
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75832 ! has exposure stimulus iron(2+) sulfate (anhydrous)
relationship: RO:0002309 CHEBI:75832 ! has exposure stimulus iron(2+) sulfate (anhydrous)

[Term]
id: ECTO:9001458
name: exposure to isoamyl acetate
def: "An exposure to isoamyl acetate." []
synonym: "isoamyl acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31725 ! has exposure stimulus isoamyl acetate
relationship: RO:0002309 CHEBI:31725 ! has exposure stimulus isoamyl acetate

[Term]
id: ECTO:9001459
name: exposure to isoamylol
def: "An exposure to isoamylol." []
synonym: "isoamylol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15837 ! has exposure stimulus isoamylol
relationship: RO:0002309 CHEBI:15837 ! has exposure stimulus isoamylol

[Term]
id: ECTO:9001460
name: exposure to isobutane
def: "An exposure to isobutane." []
synonym: "isobutane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30363 ! has exposure stimulus isobutane
relationship: RO:0002309 CHEBI:30363 ! has exposure stimulus isobutane

[Term]
id: ECTO:9001461
name: exposure to isobutyl acetate
def: "An exposure to isobutyl acetate." []
synonym: "isobutyl acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50569 ! has exposure stimulus isobutyl acetate
relationship: RO:0002309 CHEBI:50569 ! has exposure stimulus isobutyl acetate

[Term]
id: ECTO:9001462
name: exposure to isopropylamine
def: "An exposure to isopropylamine." []
synonym: "isopropylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15739 ! has exposure stimulus isopropylamine
relationship: RO:0002309 CHEBI:15739 ! has exposure stimulus isopropylamine

[Term]
id: ECTO:9001463
name: exposure to magnesium oxide
def: "An exposure to magnesium oxide." []
synonym: "magnesium oxide exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31794 ! has exposure stimulus magnesium oxide
relationship: RO:0002309 CHEBI:31794 ! has exposure stimulus magnesium oxide

[Term]
id: ECTO:9001464
name: exposure to malonaldehyde
def: "An exposure to malonaldehyde." []
synonym: "malonaldehyde exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:566274 ! has exposure stimulus malonaldehyde
relationship: RO:0002309 CHEBI:566274 ! has exposure stimulus malonaldehyde

[Term]
id: ECTO:9001465
name: exposure to methoxyflurane
def: "An exposure to methoxyflurane." []
synonym: "methoxyflurane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6843 ! has exposure stimulus methoxyflurane
relationship: RO:0002309 CHEBI:6843 ! has exposure stimulus methoxyflurane

[Term]
id: ECTO:9001466
name: exposure to methyl acetate
def: "An exposure to methyl acetate." []
synonym: "methyl acetate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77700 ! has exposure stimulus methyl acetate
relationship: RO:0002309 CHEBI:77700 ! has exposure stimulus methyl acetate

[Term]
id: ECTO:9001467
name: exposure to dimethoxymethane
def: "An exposure to dimethoxymethane." []
synonym: "dimethoxymethane exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48341 ! has exposure stimulus dimethoxymethane
relationship: RO:0002309 CHEBI:48341 ! has exposure stimulus dimethoxymethane

[Term]
id: ECTO:9001468
name: exposure to heptan-2-one
def: "An exposure to heptan-2-one." []
synonym: "heptan-2-one exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5672 ! has exposure stimulus heptan-2-one
relationship: RO:0002309 CHEBI:5672 ! has exposure stimulus heptan-2-one

[Term]
id: ECTO:9001470
name: exposure to methyl formate
def: "An exposure to methyl formate." []
synonym: "methyl formate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77699 ! has exposure stimulus methyl formate
relationship: RO:0002309 CHEBI:77699 ! has exposure stimulus methyl formate

[Term]
id: ECTO:9001471
name: exposure to methanethiol
def: "An exposure to methanethiol." []
synonym: "methanethiol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16007 ! has exposure stimulus methanethiol
relationship: RO:0002309 CHEBI:16007 ! has exposure stimulus methanethiol

[Term]
id: ECTO:9001472
name: exposure to monocrotophos
def: "An exposure to monocrotophos." []
synonym: "monocrotophos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38728 ! has exposure stimulus monocrotophos
relationship: RO:0002309 CHEBI:38728 ! has exposure stimulus monocrotophos

[Term]
id: ECTO:9001473
name: exposure to morpholine
def: "An exposure to morpholine." []
synonym: "morpholine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34856 ! has exposure stimulus morpholine
relationship: RO:0002309 CHEBI:34856 ! has exposure stimulus morpholine

[Term]
id: ECTO:9001474
name: exposure to tetracarbonylnickel
def: "An exposure to tetracarbonylnickel." []
synonym: "tetracarbonylnickel exposure" EXACT []
is_a: ECTO:9000063 ! exposure to nickel
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30372 ! has exposure stimulus tetracarbonylnickel
relationship: RO:0002309 CHEBI:30372 ! has exposure stimulus tetracarbonylnickel

[Term]
id: ECTO:9001475
name: exposure to nitroethane
def: "An exposure to nitroethane." []
synonym: "nitroethane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16268 ! has exposure stimulus nitroethane
relationship: RO:0002309 CHEBI:16268 ! has exposure stimulus nitroethane

[Term]
id: ECTO:9001476
name: exposure to nitrogen trifluoride
def: "An exposure to nitrogen trifluoride." []
synonym: "nitrogen trifluoride exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30231 ! has exposure stimulus nitrogen trifluoride
relationship: RO:0002309 CHEBI:30231 ! has exposure stimulus nitrogen trifluoride

[Term]
id: ECTO:9001477
name: exposure to 3-nitrotoluene
def: "An exposure to 3-nitrotoluene." []
synonym: "3-nitrotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39931 ! has exposure stimulus 3-nitrotoluene
relationship: RO:0002309 CHEBI:39931 ! has exposure stimulus 3-nitrotoluene

[Term]
id: ECTO:9001479
name: exposure to octane
def: "An exposure to octane." []
synonym: "octane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17590 ! has exposure stimulus octane
relationship: RO:0002309 CHEBI:17590 ! has exposure stimulus octane

[Term]
id: ECTO:9001480
name: exposure to oxalic acid
def: "An exposure to oxalic acid." []
synonym: "oxalic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16995 ! has exposure stimulus oxalic acid
relationship: RO:0002309 CHEBI:16995 ! has exposure stimulus oxalic acid

[Term]
id: ECTO:9001481
name: exposure to oxygen difluoride
def: "An exposure to oxygen difluoride." []
synonym: "oxygen difluoride exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30494 ! has exposure stimulus oxygen difluoride
relationship: RO:0002309 CHEBI:30494 ! has exposure stimulus oxygen difluoride

[Term]
id: ECTO:9001482
name: exposure to parathion
def: "An exposure to parathion." []
synonym: "parathion exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27928 ! has exposure stimulus parathion
relationship: RO:0002309 CHEBI:27928 ! has exposure stimulus parathion

[Term]
id: ECTO:9001483
name: exposure to pentane
def: "An exposure to pentane." []
synonym: "pentane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37830 ! has exposure stimulus pentane
relationship: RO:0002309 CHEBI:37830 ! has exposure stimulus pentane

[Term]
id: ECTO:9001484
name: exposure to pentan-2-one
def: "An exposure to pentan-2-one." []
synonym: "pentan-2-one exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16472 ! has exposure stimulus pentan-2-one
relationship: RO:0002309 CHEBI:16472 ! has exposure stimulus pentan-2-one

[Term]
id: ECTO:9001485
name: exposure to 10H-phenothiazine
def: "An exposure to 10H-phenothiazine." []
synonym: "10H-phenothiazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37931 ! has exposure stimulus 10H-phenothiazine
relationship: RO:0002309 CHEBI:37931 ! has exposure stimulus 10H-phenothiazine

[Term]
id: ECTO:9001486
name: exposure to phorate
def: "An exposure to phorate." []
synonym: "phorate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38764 ! has exposure stimulus phorate
relationship: RO:0002309 CHEBI:38764 ! has exposure stimulus phorate

[Term]
id: ECTO:9001487
name: exposure to phosphane
def: "An exposure to phosphane." []
synonym: "phosphane exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001226 ! exposure to phosphine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30278 ! has exposure stimulus phosphane
relationship: RO:0002309 CHEBI:30278 ! has exposure stimulus phosphane

[Term]
id: ECTO:9001489
name: exposure to phosphoryl trichloride
def: "An exposure to phosphoryl trichloride." []
synonym: "phosphoryl trichloride exposure" EXACT []
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30336 ! has exposure stimulus phosphoryl trichloride
relationship: RO:0002309 CHEBI:30336 ! has exposure stimulus phosphoryl trichloride

[Term]
id: ECTO:9001490
name: exposure to phosphorus trichloride
def: "An exposure to phosphorus trichloride." []
synonym: "phosphorus trichloride exposure" EXACT []
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30334 ! has exposure stimulus phosphorus trichloride
relationship: RO:0002309 CHEBI:30334 ! has exposure stimulus phosphorus trichloride

[Term]
id: ECTO:9001492
name: exposure to propane
def: "An exposure to propane." []
synonym: "propane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32879 ! has exposure stimulus propane
relationship: RO:0002309 CHEBI:32879 ! has exposure stimulus propane

[Term]
id: ECTO:9001493
name: exposure to propane-1-thiol
def: "An exposure to propane-1-thiol." []
synonym: "propane-1-thiol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8473 ! has exposure stimulus propane-1-thiol
relationship: RO:0002309 CHEBI:8473 ! has exposure stimulus propane-1-thiol

[Term]
id: ECTO:9001494
name: exposure to propionic acid
def: "An exposure to propionic acid." []
synonym: "propionic acid exposure" EXACT []
is_a: ECTO:9002880 ! exposure to short-chain fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30768 ! has exposure stimulus propionic acid
relationship: RO:0002309 CHEBI:30768 ! has exposure stimulus propionic acid

[Term]
id: ECTO:9001495
name: exposure to propionitrile
def: "An exposure to propionitrile." []
synonym: "propionitrile exposure" EXACT []
is_a: ECTO:9001621 ! exposure to volatile organic compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26307 ! has exposure stimulus propionitrile
relationship: RO:0002309 CHEBI:26307 ! has exposure stimulus propionitrile

[Term]
id: ECTO:9001496
name: exposure to resorcinol
def: "An exposure to resorcinol." []
synonym: "resorcinol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27810 ! has exposure stimulus resorcinol
relationship: RO:0002309 CHEBI:27810 ! has exposure stimulus resorcinol

[Term]
id: ECTO:9001497
name: exposure to silicon carbide
def: "An exposure to silicon carbide." []
synonym: "silicon carbide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29390 ! has exposure stimulus silicon carbide
relationship: RO:0002309 CHEBI:29390 ! has exposure stimulus silicon carbide

[Term]
id: ECTO:9001498
name: exposure to silane
def: "An exposure to silane." []
synonym: "silane exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29389 ! has exposure stimulus silane
relationship: RO:0002309 CHEBI:29389 ! has exposure stimulus silane

[Term]
id: ECTO:9001499
name: exposure to trisodium hexafluoroaluminate
def: "An exposure to trisodium hexafluoroaluminate." []
synonym: "trisodium hexafluoroaluminate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39289 ! has exposure stimulus trisodium hexafluoroaluminate
relationship: RO:0002309 CHEBI:39289 ! has exposure stimulus trisodium hexafluoroaluminate

[Term]
id: ECTO:9001500
name: exposure to stibane
def: "An exposure to stibane." []
synonym: "stibane exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000939 ! exposure to antimony
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30288 ! has exposure stimulus stibane
relationship: RO:0002309 CHEBI:30288 ! has exposure stimulus stibane

[Term]
id: ECTO:9001501
name: exposure to sulfur hexafluoride
def: "An exposure to sulfur hexafluoride." []
synonym: "sulfur hexafluoride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30496 ! has exposure stimulus sulfur hexafluoride
relationship: RO:0002309 CHEBI:30496 ! has exposure stimulus sulfur hexafluoride

[Term]
id: ECTO:9001502
name: exposure to sulfur tetrafluoride
def: "An exposure to sulfur tetrafluoride." []
synonym: "sulfur tetrafluoride exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30495 ! has exposure stimulus sulfur tetrafluoride
relationship: RO:0002309 CHEBI:30495 ! has exposure stimulus sulfur tetrafluoride

[Term]
id: ECTO:9001503
name: exposure to (2,4,5-trichlorophenoxy)acetic acid
def: "An exposure to (2,4,5-trichlorophenoxy)acetic acid." []
synonym: "(2,4,5-trichlorophenoxy)acetic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27903 ! has exposure stimulus (2,4,5-trichlorophenoxy)acetic acid
relationship: RO:0002309 CHEBI:27903 ! has exposure stimulus (2,4,5-trichlorophenoxy)acetic acid

[Term]
id: ECTO:9001504
name: exposure to 1,4-diphenylbenzene
def: "An exposure to 1,4-diphenylbenzene." []
synonym: "1,4-diphenylbenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52242 ! has exposure stimulus 1,4-diphenylbenzene
relationship: RO:0002309 CHEBI:52242 ! has exposure stimulus 1,4-diphenylbenzene

[Term]
id: ECTO:9001505
name: exposure to tetraethyllead
def: "An exposure to tetraethyllead." []
synonym: "tetraethyllead exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000945 ! exposure to lead
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30182 ! has exposure stimulus tetraethyllead
relationship: RO:0002309 CHEBI:30182 ! has exposure stimulus tetraethyllead

[Term]
id: ECTO:9001506
name: exposure to oxolane
def: "An exposure to oxolane." []
synonym: "oxolane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26911 ! has exposure stimulus oxolane
relationship: RO:0002309 CHEBI:26911 ! has exposure stimulus oxolane

[Term]
id: ECTO:9001507
name: exposure to thioglycolic acid
def: "An exposure to thioglycolic acid." []
synonym: "thioglycolic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30065 ! has exposure stimulus thioglycolic acid
relationship: RO:0002309 CHEBI:30065 ! has exposure stimulus thioglycolic acid

[Term]
id: ECTO:9001508
name: exposure to thionyl dichloride
def: "An exposure to thionyl chloride." []
synonym: "thionyl chloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29290 ! has exposure stimulus thionyl chloride
relationship: RO:0002309 CHEBI:29290 ! has exposure stimulus thionyl chloride

[Term]
id: ECTO:9001509
name: exposure to tin dioxide
def: "An exposure to tin dioxide." []
synonym: "tin dioxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000952 ! exposure to tin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52991 ! has exposure stimulus tin dioxide
relationship: RO:0002309 CHEBI:52991 ! has exposure stimulus tin dioxide

[Term]
id: ECTO:9001510
name: exposure to titanium dioxide
def: "An exposure to titanium dioxide." []
synonym: "titanium dioxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32234 ! has exposure stimulus titanium dioxide
relationship: RO:0002309 CHEBI:32234 ! has exposure stimulus titanium dioxide

[Term]
id: ECTO:9001511
name: exposure to tributyl phosphate
def: "An exposure to tributyl phosphate." []
synonym: "tributyl phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35019 ! has exposure stimulus tributyl phosphate
relationship: RO:0002309 CHEBI:35019 ! has exposure stimulus tributyl phosphate

[Term]
id: ECTO:9001512
name: exposure to trimethylamine
def: "An exposure to trimethylamine." []
synonym: "trimethylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18139 ! has exposure stimulus trimethylamine
relationship: RO:0002309 CHEBI:18139 ! has exposure stimulus trimethylamine

[Term]
id: ECTO:9001513
name: exposure to 1,2,3-trimethylbenzene
def: "An exposure to 1,2,3-trimethylbenzene." []
synonym: "1,2,3-trimethylbenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34037 ! has exposure stimulus 1,2,3-trimethylbenzene
relationship: RO:0002309 CHEBI:34037 ! has exposure stimulus 1,2,3-trimethylbenzene

[Term]
id: ECTO:9001514
name: exposure to 1,3,5-trimethylbenzene
def: "An exposure to 1,3,5-trimethylbenzene." []
synonym: "1,3,5-trimethylbenzene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34833 ! has exposure stimulus 1,3,5-trimethylbenzene
relationship: RO:0002309 CHEBI:34833 ! has exposure stimulus 1,3,5-trimethylbenzene

[Term]
id: ECTO:9001515
name: exposure to triphenyl phosphate
def: "An exposure to triphenyl phosphate." []
synonym: "triphenyl phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35033 ! has exposure stimulus triphenyl phosphate
relationship: RO:0002309 CHEBI:35033 ! has exposure stimulus triphenyl phosphate

[Term]
id: ECTO:9001516
name: exposure to divanadium pentaoxide
def: "An exposure to divanadium pentaoxide." []
synonym: "divanadium pentaoxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001298 ! exposure to vanadium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30045 ! has exposure stimulus divanadium pentaoxide
relationship: RO:0002309 CHEBI:30045 ! has exposure stimulus divanadium pentaoxide

[Term]
id: ECTO:9001517
name: exposure to 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one
def: "An exposure to 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one." []
synonym: "4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000345 ! exposure to phenylpropanoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87732 ! has exposure stimulus 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one
relationship: RO:0002309 CHEBI:87732 ! has exposure stimulus 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one

[Term]
id: ECTO:9001518
name: exposure to zinc dichloride
def: "An exposure to zinc dichloride." []
synonym: "zinc dichloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9000954 ! exposure to zinc
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49976 ! has exposure stimulus zinc dichloride
relationship: RO:0002309 CHEBI:49976 ! has exposure stimulus zinc dichloride

[Term]
id: ECTO:9001519
name: exposure to zinc oxide
def: "An exposure to zinc oxide." []
synonym: "zinc oxide exposure" EXACT []
is_a: ECTO:9000954 ! exposure to zinc
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36560 ! has exposure stimulus zinc oxide
relationship: RO:0002309 CHEBI:36560 ! has exposure stimulus zinc oxide

[Term]
id: ECTO:9001520
name: exposure to azinphos-methyl
def: "An exposure to azinphos-methyl." []
synonym: "azinphos-methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2953 ! has exposure stimulus azinphos-methyl
relationship: RO:0002309 CHEBI:2953 ! has exposure stimulus azinphos-methyl

[Term]
id: ECTO:9001521
name: exposure to fentanyl
def: "An exposure to fentanyl." []
synonym: "fentanyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:119915 ! has exposure stimulus fentanyl
relationship: RO:0002309 CHEBI:119915 ! has exposure stimulus fentanyl

[Term]
id: ECTO:9001522
name: exposure to sarin
def: "An exposure to sarin." []
synonym: "sarin exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75701 ! has exposure stimulus sarin
relationship: RO:0002309 CHEBI:75701 ! has exposure stimulus sarin

[Term]
id: ECTO:9001523
name: exposure to strychnine
def: "An exposure to strychnine." []
synonym: "strychnine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28973 ! has exposure stimulus strychnine
relationship: RO:0002309 CHEBI:28973 ! has exposure stimulus strychnine

[Term]
id: ECTO:9001524
name: exposure to Ricin
def: "An exposure to Ricin." []
synonym: "Ricin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8852 ! has exposure stimulus Ricin
relationship: RO:0002309 CHEBI:8852 ! has exposure stimulus Ricin

[Term]
id: ECTO:9001525
name: exposure to bis(2-ethylhexyl) phthalate
def: "An exposure to bis(2-ethylhexyl) phthalate." []
synonym: "bis(2-ethylhexyl) phthalate exposure" EXACT []
is_a: ECTO:9000906 ! exposure to phthalate ester
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17747 ! has exposure stimulus bis(2-ethylhexyl) phthalate
relationship: RO:0002309 CHEBI:17747 ! has exposure stimulus bis(2-ethylhexyl) phthalate

[Term]
id: ECTO:9001526
name: exposure to 1,1-dimethylhydrazine
def: "An exposure to 1,1-dimethylhydrazine." []
synonym: "1,1-dimethylhydrazine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18853 ! has exposure stimulus 1,1-dimethylhydrazine
relationship: RO:0002309 CHEBI:18853 ! has exposure stimulus 1,1-dimethylhydrazine

[Term]
id: ECTO:9001527
name: exposure to 1,3-dichloropropene
def: "An exposure to 1,3-dichloropropene." []
synonym: "1,3-dichloropropene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18918 ! has exposure stimulus 1,3-dichloropropene
relationship: RO:0002309 CHEBI:18918 ! has exposure stimulus 1,3-dichloropropene

[Term]
id: ECTO:9001528
name: exposure to sodium hydrogensulfite
def: "An exposure to sodium hydrogensulfite." []
synonym: "sodium hydrogensulfite exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26709 ! has exposure stimulus sodium hydrogensulfite
relationship: RO:0002309 CHEBI:26709 ! has exposure stimulus sodium hydrogensulfite

[Term]
id: ECTO:9001529
name: exposure to sodium fluoride
def: "An exposure to sodium fluoride." []
synonym: "sodium fluoride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9001124 ! exposure to fluorine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28741 ! has exposure stimulus sodium fluoride
relationship: RO:0002309 CHEBI:28741 ! has exposure stimulus sodium fluoride

[Term]
id: ECTO:9001530
name: exposure to mechlorethamine
def: "An exposure to mechlorethamine." []
synonym: "mechlorethamine exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28925 ! has exposure stimulus mechlorethamine
relationship: RO:0002309 CHEBI:28925 ! has exposure stimulus mechlorethamine

[Term]
id: ECTO:9001531
name: exposure to copper(2+)
def: "An exposure to copper(2+)." []
synonym: "copper(2+) exposure" EXACT []
is_a: ECTO:9000288 ! exposure to copper cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29036 ! has exposure stimulus copper(2+)
relationship: RO:0002309 CHEBI:29036 ! has exposure stimulus copper(2+)

[Term]
id: ECTO:9001533
name: obsolete toluene 2,4-diisocyanate exposure
is_obsolete: true
replaced_by: ECTO:9000103

[Term]
id: ECTO:9001534
name: exposure to organochlorine insecticide
def: "An exposure to organochlorine insecticide." []
synonym: "organochlorine insecticide exposure" EXACT []
is_a: ECTO:9001535 ! exposure to organochlorine pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25705 ! has exposure stimulus organochlorine insecticide
relationship: RO:0002309 CHEBI:25705 ! has exposure stimulus organochlorine insecticide

[Term]
id: ECTO:9001535
name: exposure to organochlorine pesticide
def: "An exposure to organochlorine pesticide." []
synonym: "organochlorine pesticide exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38656 ! has exposure stimulus organochlorine pesticide
relationship: RO:0002309 CHEBI:38656 ! has exposure stimulus organochlorine pesticide

[Term]
id: ECTO:9001536
name: exposure to 1,4 dioxin
def: "An exposure to 1,4-dioxine." []
synonym: "1,4-dioxine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134044 ! has exposure stimulus 1,4-dioxine
relationship: RO:0002309 CHEBI:134044 ! has exposure stimulus 1,4-dioxine

[Term]
id: ECTO:9001537
name: exposure to polychlorinated dibenzodioxines and related compounds
def: "An exposure to polychlorinated dibenzodioxines and related compounds." []
synonym: "polychlorinated dibenzodioxines and related compounds exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134045 ! has exposure stimulus polychlorinated dibenzodioxines and related compounds
relationship: RO:0002309 CHEBI:134045 ! has exposure stimulus polychlorinated dibenzodioxines and related compounds

[Term]
id: ECTO:9001538
name: exposure to polybromobiphenyl
def: "An exposure to polybromobiphenyl." []
synonym: "exposure to PBB" EXACT []
synonym: "exposure to polybrominated biphenyl" EXACT []
synonym: "polybromobiphenyl exposure" EXACT []
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9001537 ! exposure to polychlorinated dibenzodioxines and related compounds
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134049 ! has exposure stimulus polybromobiphenyl
relationship: RO:0002309 CHEBI:134049 ! has exposure stimulus polybromobiphenyl

[Term]
id: ECTO:9001539
name: exposure to polychlorinated dibenzofuran
def: "An exposure to polychlorinated dibenzofuran." []
synonym: "polychlorinated dibenzofuran exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001537 ! exposure to polychlorinated dibenzodioxines and related compounds
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134046 ! has exposure stimulus polychlorinated dibenzofuran
relationship: RO:0002309 CHEBI:134046 ! has exposure stimulus polychlorinated dibenzofuran

[Term]
id: ECTO:9001540
name: exposure to disodium 5'-guanylate
def: "An exposure to disodium 5'-guanylate." []
synonym: "disodium 5'-guanylate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132932 ! has exposure stimulus disodium 5'-guanylate
relationship: RO:0002309 CHEBI:132932 ! has exposure stimulus disodium 5'-guanylate

[Term]
id: ECTO:9001541
name: exposure to phenylureas
def: "An exposure to phenylureas." []
synonym: "phenylureas exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134043 ! has exposure stimulus phenylureas
relationship: RO:0002309 CHEBI:134043 ! has exposure stimulus phenylureas

[Term]
id: ECTO:9001542
name: exposure to chlorofluorocarbon
def: "An exposure to chlorofluorocarbon." []
synonym: "chlorofluorocarbon exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001621 ! exposure to volatile organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134024 ! has exposure stimulus chlorofluorocarbon
relationship: RO:0002309 CHEBI:134024 ! has exposure stimulus chlorofluorocarbon

[Term]
id: ECTO:9001543
name: exposure to ethylparaben
def: "An exposure to ethylparaben." []
synonym: "ethylparaben exposure" EXACT []
is_a: ECTO:9000930 ! exposure to paraben
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31575 ! has exposure stimulus ethylparaben
relationship: RO:0002309 CHEBI:31575 ! has exposure stimulus ethylparaben

[Term]
id: ECTO:9001544
name: exposure to propylparaben
def: "An exposure to propylparaben." []
synonym: "propylparaben exposure" EXACT []
is_a: ECTO:9000930 ! exposure to paraben
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32063 ! has exposure stimulus propylparaben
relationship: RO:0002309 CHEBI:32063 ! has exposure stimulus propylparaben

[Term]
id: ECTO:9001545
name: exposure to hafnium atom
def: "An exposure to hafnium atom." []
synonym: "hafnium atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33343 ! has exposure stimulus hafnium atom
relationship: RO:0002309 CHEBI:33343 ! has exposure stimulus hafnium atom

[Term]
id: ECTO:9001546
name: exposure to Ammonium sulfamate
def: "An exposure to Ammonium sulfamate." []
synonym: "Ammonium sulfamate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81950 ! has exposure stimulus Ammonium sulfamate
relationship: RO:0002309 CHEBI:81950 ! has exposure stimulus Ammonium sulfamate

[Term]
id: ECTO:9001547
name: exposure to pentyl acetate
def: "An exposure to pentyl acetate." []
synonym: "pentyl acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87362 ! has exposure stimulus pentyl acetate
relationship: RO:0002309 CHEBI:87362 ! has exposure stimulus pentyl acetate

[Term]
id: ECTO:9001548
name: exposure to ANTU
def: "An exposure to ANTU." []
synonym: "ANTU exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82256 ! has exposure stimulus ANTU
relationship: RO:0002309 CHEBI:82256 ! has exposure stimulus ANTU

[Term]
id: ECTO:9001550
name: exposure to barium chloride
def: "An exposure to barium chloride." []
synonym: "barium chloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9000940 ! exposure to barium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63317 ! has exposure stimulus barium chloride
relationship: RO:0002309 CHEBI:63317 ! has exposure stimulus barium chloride

[Term]
id: ECTO:9001552
name: exposure to calcium oxide
def: "An exposure to calcium oxide." []
synonym: "calcium oxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31344 ! has exposure stimulus calcium oxide
relationship: RO:0002309 CHEBI:31344 ! has exposure stimulus calcium oxide

[Term]
id: ECTO:9001553
name: exposure to chloroacetaldehyde
def: "An exposure to chloroacetaldehyde." []
synonym: "chloroacetaldehyde exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27871 ! has exposure stimulus chloroacetaldehyde
relationship: RO:0002309 CHEBI:27871 ! has exposure stimulus chloroacetaldehyde

[Term]
id: ECTO:9001554
name: exposure to Chloroacetyl chloride
def: "An exposure to Chloroacetyl chloride." []
synonym: "Chloroacetyl chloride exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34624 ! has exposure stimulus Chloroacetyl chloride
relationship: RO:0002309 CHEBI:34624 ! has exposure stimulus Chloroacetyl chloride

[Term]
id: ECTO:9001555
name: exposure to copper(II) oxide
def: "An exposure to copper(II) oxide." []
synonym: "copper(II) oxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000944 ! exposure to copper
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75955 ! has exposure stimulus copper(II) oxide
relationship: RO:0002309 CHEBI:75955 ! has exposure stimulus copper(II) oxide

[Term]
id: ECTO:9001556
name: exposure to Crufomate
def: "An exposure to Crufomate." []
synonym: "Crufomate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82111 ! has exposure stimulus Crufomate
relationship: RO:0002309 CHEBI:82111 ! has exposure stimulus Crufomate

[Term]
id: ECTO:9001557
name: exposure to Dichloroacetylene
def: "An exposure to Dichloroacetylene." []
synonym: "Dichloroacetylene exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4503 ! has exposure stimulus Dichloroacetylene
relationship: RO:0002309 CHEBI:4503 ! has exposure stimulus Dichloroacetylene

[Term]
id: ECTO:9001558
name: exposure to Bis(2-chloroethyl)ether
def: "An exposure to Bis(2-chloroethyl)ether." []
synonym: "Bis(2-chloroethyl)ether exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34573 ! has exposure stimulus Bis(2-chloroethyl)ether
relationship: RO:0002309 CHEBI:34573 ! has exposure stimulus Bis(2-chloroethyl)ether

[Term]
id: ECTO:9001559
name: exposure to Dalapon
def: "An exposure to Dalapon." []
synonym: "Dalapon exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81859 ! has exposure stimulus Dalapon
relationship: RO:0002309 CHEBI:81859 ! has exposure stimulus Dalapon

[Term]
id: ECTO:9001560
name: exposure to dicrotophos
def: "An exposure to dicrotophos." []
synonym: "dicrotophos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38658 ! has exposure stimulus dicrotophos
relationship: RO:0002309 CHEBI:38658 ! has exposure stimulus dicrotophos

[Term]
id: ECTO:9001561
name: exposure to diethylamine
def: "An exposure to diethylamine." []
synonym: "diethylamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85259 ! has exposure stimulus diethylamine
relationship: RO:0002309 CHEBI:85259 ! has exposure stimulus diethylamine

[Term]
id: ECTO:9001562
name: exposure to pentan-3-one
def: "An exposure to pentan-3-one." []
synonym: "pentan-3-one exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87755 ! has exposure stimulus pentan-3-one
relationship: RO:0002309 CHEBI:87755 ! has exposure stimulus pentan-3-one

[Term]
id: ECTO:9001563
name: exposure to 2-Methyl-4-heptanone
def: "An exposure to 2-Methyl-4-heptanone." []
synonym: "2-Methyl-4-heptanone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:89195 ! has exposure stimulus 2-Methyl-4-heptanone
relationship: RO:0002309 CHEBI:89195 ! has exposure stimulus 2-Methyl-4-heptanone

[Term]
id: ECTO:9001564
name: exposure to N,N-dimethylacetamide
def: "An exposure to N,N-dimethylacetamide." []
synonym: "N,N-dimethylacetamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84254 ! has exposure stimulus N,N-dimethylacetamide
relationship: RO:0002309 CHEBI:84254 ! has exposure stimulus N,N-dimethylacetamide

[Term]
id: ECTO:9001565
name: exposure to Dimethylcarbamoyl chloride
def: "An exposure to Dimethylcarbamoyl chloride." []
synonym: "Dimethylcarbamoyl chloride exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82280 ! has exposure stimulus Dimethylcarbamoyl chloride
relationship: RO:0002309 CHEBI:82280 ! has exposure stimulus Dimethylcarbamoyl chloride

[Term]
id: ECTO:9001566
name: exposure to Dioxation
def: "An exposure to Dioxation." []
synonym: "Dioxation exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81364 ! has exposure stimulus Dioxation
relationship: RO:0002309 CHEBI:81364 ! has exposure stimulus Dioxation

[Term]
id: ECTO:9001567
name: exposure to 4-Heptanone
def: "An exposure to 4-heptanone." []
synonym: "4-heptanone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:89484 ! has exposure stimulus 4-heptanone
relationship: RO:0002309 CHEBI:89484 ! has exposure stimulus 4-heptanone

[Term]
id: ECTO:9001568
name: exposure to diquat
def: "An exposure to diquat." []
synonym: "diquat exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64163 ! has exposure stimulus diquat
relationship: RO:0002309 CHEBI:64163 ! has exposure stimulus diquat

[Term]
id: ECTO:9001569
name: exposure to EPN
def: "An exposure to EPN." []
synonym: "EPN exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34733 ! has exposure stimulus EPN
relationship: RO:0002309 CHEBI:34733 ! has exposure stimulus EPN

[Term]
id: ECTO:9001570
name: exposure to heptan-3-one
def: "An exposure to heptan-3-one." []
synonym: "heptan-3-one exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50139 ! has exposure stimulus heptan-3-one
relationship: RO:0002309 CHEBI:50139 ! has exposure stimulus heptan-3-one

[Term]
id: ECTO:9001571
name: exposure to Ethylenethiourea
def: "An exposure to Ethylenethiourea." []
synonym: "Ethylenethiourea exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34750 ! has exposure stimulus Ethylenethiourea
relationship: RO:0002309 CHEBI:34750 ! has exposure stimulus Ethylenethiourea

[Term]
id: ECTO:9001572
name: exposure to fensulfothion
def: "An exposure to fensulfothion." []
synonym: "fensulfothion exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34760 ! has exposure stimulus fensulfothion
relationship: RO:0002309 CHEBI:34760 ! has exposure stimulus fensulfothion

[Term]
id: ECTO:9001573
name: exposure to fonofos
def: "An exposure to fonofos." []
synonym: "fonofos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38689 ! has exposure stimulus fonofos
relationship: RO:0002309 CHEBI:38689 ! has exposure stimulus fonofos

[Term]
id: ECTO:9001574
name: exposure to formamide
def: "An exposure to formamide." []
synonym: "formamide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16397 ! has exposure stimulus formamide
relationship: RO:0002309 CHEBI:16397 ! has exposure stimulus formamide

[Term]
id: ECTO:9001575
name: exposure to glutaraldehyde
def: "An exposure to glutaraldehyde." []
synonym: "glutaraldehyde exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64276 ! has exposure stimulus glutaraldehyde
relationship: RO:0002309 CHEBI:64276 ! has exposure stimulus glutaraldehyde

[Term]
id: ECTO:9001576
name: exposure to glycerol
def: "An exposure to glycerol." []
synonym: "glycerol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9001449 ! exposure to alditol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17754 ! has exposure stimulus glycerol
relationship: RO:0002309 CHEBI:17754 ! has exposure stimulus glycerol

[Term]
id: ECTO:9001577
name: exposure to 2-methylpentane-2,4-diol
def: "An exposure to 2-methylpentane-2,4-diol." []
synonym: "2-methylpentane-2,4-diol exposure" EXACT []
is_a: ECTO:9002156 ! exposure to glycol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62995 ! has exposure stimulus 2-methylpentane-2,4-diol
relationship: RO:0002309 CHEBI:62995 ! has exposure stimulus 2-methylpentane-2,4-diol

[Term]
id: ECTO:9001578
name: exposure to selane
def: "An exposure to selane." []
synonym: "selane exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000950 ! exposure to selenium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16503 ! has exposure stimulus selane
relationship: RO:0002309 CHEBI:16503 ! has exposure stimulus selane

[Term]
id: ECTO:9001579
name: exposure to elemental indium
def: "An exposure to elemental indium." []
synonym: "elemental indium exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37114 ! has exposure stimulus elemental indium
relationship: RO:0002309 CHEBI:37114 ! has exposure stimulus elemental indium

[Term]
id: ECTO:9001580
name: exposure to 3-methyl-2-butanol
def: "An exposure to 3-methyl-2-butanol." []
synonym: "3-methyl-2-butanol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77517 ! has exposure stimulus 3-methyl-2-butanol
relationship: RO:0002309 CHEBI:77517 ! has exposure stimulus 3-methyl-2-butanol

[Term]
id: ECTO:9001581
name: exposure to isophorone
def: "An exposure to isophorone." []
synonym: "isophorone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34800 ! has exposure stimulus isophorone
relationship: RO:0002309 CHEBI:34800 ! has exposure stimulus isophorone

[Term]
id: ECTO:9001582
name: exposure to 4-Methyl-3-penten-2-one, 9CI
def: "An exposure to 4-Methyl-3-penten-2-one, 9CI." []
synonym: "4-Methyl-3-penten-2-one, 9CI exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:89993 ! has exposure stimulus 4-Methyl-3-penten-2-one, 9CI
relationship: RO:0002309 CHEBI:89993 ! has exposure stimulus 4-Methyl-3-penten-2-one, 9CI

[Term]
id: ECTO:9001583
name: exposure to methacrylic acid
def: "An exposure to methacrylic acid." []
synonym: "methacrylic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25219 ! has exposure stimulus methacrylic acid
relationship: RO:0002309 CHEBI:25219 ! has exposure stimulus methacrylic acid

[Term]
id: ECTO:9001584
name: exposure to p-methoxyphenol
def: "An exposure to p-methoxyphenol." []
synonym: "p-methoxyphenol exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:69441 ! has exposure stimulus p-methoxyphenol
relationship: RO:0002309 CHEBI:69441 ! has exposure stimulus p-methoxyphenol

[Term]
id: ECTO:9001585
name: exposure to 4,4'-methylene-bis-(2-chloroaniline)
def: "An exposure to 4,4'-methylene-bis-(2-chloroaniline)." []
synonym: "4,4'-methylene-bis-(2-chloroaniline) exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28124 ! has exposure stimulus 4,4'-methylene-bis-(2-chloroaniline)
relationship: RO:0002309 CHEBI:28124 ! has exposure stimulus 4,4'-methylene-bis-(2-chloroaniline)

[Term]
id: ECTO:9001586
name: exposure to dicyclohexylmethane-4,4'-diisocyanate
def: "An exposure to dicyclohexylmethane-4,4'-diisocyanate." []
synonym: "dicyclohexylmethane-4,4'-diisocyanate exposure" EXACT []
is_a: ECTO:9001309 ! exposure to diisocyanate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53216 ! has exposure stimulus dicyclohexylmethane-4,4'-diisocyanate
relationship: RO:0002309 CHEBI:53216 ! has exposure stimulus dicyclohexylmethane-4,4'-diisocyanate

[Term]
id: ECTO:9001587
name: exposure to 5-Methyl-2-hexanone
def: "An exposure to 5-methyl-2-hexanone." []
synonym: "5-methyl-2-hexanone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88432 ! has exposure stimulus 5-methyl-2-hexanone
relationship: RO:0002309 CHEBI:88432 ! has exposure stimulus 5-methyl-2-hexanone

[Term]
id: ECTO:9001588
name: exposure to alpha-Methylstyrene
def: "An exposure to alpha-Methylstyrene." []
synonym: "alpha-Methylstyrene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35060 ! has exposure stimulus alpha-Methylstyrene
relationship: RO:0002309 CHEBI:35060 ! has exposure stimulus alpha-Methylstyrene

[Term]
id: ECTO:9001589
name: exposure to N-methylaniline
def: "An exposure to N-methylaniline." []
synonym: "N-methylaniline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15733 ! has exposure stimulus N-methylaniline
relationship: RO:0002309 CHEBI:15733 ! has exposure stimulus N-methylaniline

[Term]
id: ECTO:9001590
name: exposure to 4-Chloronitrobenzene
def: "An exposure to 4-Chloronitrobenzene." []
synonym: "4-Chloronitrobenzene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34399 ! has exposure stimulus 4-Chloronitrobenzene
relationship: RO:0002309 CHEBI:34399 ! has exposure stimulus 4-Chloronitrobenzene

[Term]
id: ECTO:9001591
name: exposure to 2-nitronaphthalene
def: "An exposure to 2-nitronaphthalene." []
synonym: "2-nitronaphthalene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50637 ! has exposure stimulus 2-nitronaphthalene
relationship: RO:0002309 CHEBI:50637 ! has exposure stimulus 2-nitronaphthalene

[Term]
id: ECTO:9001592
name: exposure to 1-nitropropane
def: "An exposure to 1-nitropropane." []
synonym: "1-nitropropane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76261 ! has exposure stimulus 1-nitropropane
relationship: RO:0002309 CHEBI:76261 ! has exposure stimulus 1-nitropropane

[Term]
id: ECTO:9001593
name: exposure to 4-nitrotoluene
def: "An exposure to 4-nitrotoluene." []
synonym: "4-nitrotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35227 ! has exposure stimulus 4-nitrotoluene
relationship: RO:0002309 CHEBI:35227 ! has exposure stimulus 4-nitrotoluene

[Term]
id: ECTO:9001594
name: exposure to Phenyl glycidyl ether
def: "An exposure to Phenyl glycidyl ether." []
synonym: "Phenyl glycidyl ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82367 ! has exposure stimulus Phenyl glycidyl ether
relationship: RO:0002309 CHEBI:82367 ! has exposure stimulus Phenyl glycidyl ether

[Term]
id: ECTO:9001595
name: exposure to N-Phenyl-2-naphthylamine
def: "An exposure to N-Phenyl-2-naphthylamine." []
synonym: "N-Phenyl-2-naphthylamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34877 ! has exposure stimulus N-Phenyl-2-naphthylamine
relationship: RO:0002309 CHEBI:34877 ! has exposure stimulus N-Phenyl-2-naphthylamine

[Term]
id: ECTO:9001596
name: exposure to phosphorus pentachloride
def: "An exposure to phosphorus pentachloride." []
synonym: "phosphorus pentachloride exposure" EXACT []
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30335 ! has exposure stimulus phosphorus pentachloride
relationship: RO:0002309 CHEBI:30335 ! has exposure stimulus phosphorus pentachloride

[Term]
id: ECTO:9001597
name: exposure to isophthalonitrile
def: "An exposure to isophthalonitrile." []
synonym: "isophthalonitrile exposure" EXACT []
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38218 ! has exposure stimulus isophthalonitrile
relationship: RO:0002309 CHEBI:38218 ! has exposure stimulus isophthalonitrile

[Term]
id: ECTO:9001598
name: exposure to Pindone
def: "An exposure to Pindone." []
synonym: "Pindone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82261 ! has exposure stimulus Pindone
relationship: RO:0002309 CHEBI:82261 ! has exposure stimulus Pindone

[Term]
id: ECTO:9001599
name: exposure to 1,3-Propane sultone
def: "An exposure to 1,3-Propane sultone." []
synonym: "1,3-Propane sultone exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82370 ! has exposure stimulus 1,3-Propane sultone
relationship: RO:0002309 CHEBI:82370 ! has exposure stimulus 1,3-Propane sultone

[Term]
id: ECTO:9001600
name: exposure to propyl acetate
def: "An exposure to propyl acetate." []
synonym: "propyl acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:40116 ! has exposure stimulus propyl acetate
relationship: RO:0002309 CHEBI:40116 ! has exposure stimulus propyl acetate

[Term]
id: ECTO:9001601
name: exposure to rhodium
def: "An exposure to rhodium atom." []
synonym: "rhodium atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33359 ! has exposure stimulus rhodium atom
relationship: RO:0002309 CHEBI:33359 ! has exposure stimulus rhodium atom

[Term]
id: ECTO:9001602
name: exposure to Fenchlorphos
def: "An exposure to Fenchlorphos." []
synonym: "Fenchlorphos exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82125 ! has exposure stimulus Fenchlorphos
relationship: RO:0002309 CHEBI:82125 ! has exposure stimulus Fenchlorphos

[Term]
id: ECTO:9001603
name: exposure to selenium hexafluoride
def: "An exposure to selenium hexafluoride." []
synonym: "selenium hexafluoride exposure" EXACT []
is_a: ECTO:9000950 ! exposure to selenium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30434 ! has exposure stimulus selenium hexafluoride
relationship: RO:0002309 CHEBI:30434 ! has exposure stimulus selenium hexafluoride

[Term]
id: ECTO:9001604
name: exposure to tantalum
def: "An exposure to tantalum atom." []
synonym: "tantalum atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33348 ! has exposure stimulus tantalum atom
relationship: RO:0002309 CHEBI:33348 ! has exposure stimulus tantalum atom

[Term]
id: ECTO:9001605
name: exposure to sulfotep
def: "An exposure to sulfotep." []
synonym: "sulfotep exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38945 ! has exposure stimulus sulfotep
relationship: RO:0002309 CHEBI:38945 ! has exposure stimulus sulfotep

[Term]
id: ECTO:9001606
name: exposure to tellurium hexafluoride
def: "An exposure to tellurium hexafluoride." []
synonym: "tellurium hexafluoride exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30469 ! has exposure stimulus tellurium hexafluoride
relationship: RO:0002309 CHEBI:30469 ! has exposure stimulus tellurium hexafluoride

[Term]
id: ECTO:9001607
name: exposure to TEPP
def: "An exposure to TEPP." []
synonym: "TEPP exposure" EXACT []
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82149 ! has exposure stimulus TEPP
relationship: RO:0002309 CHEBI:82149 ! has exposure stimulus TEPP

[Term]
id: ECTO:9001608
name: exposure to tetramethyllead
def: "An exposure to tetramethyllead." []
synonym: "tetramethyllead exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000945 ! exposure to lead
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30183 ! has exposure stimulus tetramethyllead
relationship: RO:0002309 CHEBI:30183 ! has exposure stimulus tetramethyllead

[Term]
id: ECTO:9001609
name: exposure to sodium diphosphate
def: "An exposure to sodium diphosphate." []
synonym: "sodium diphosphate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71240 ! has exposure stimulus sodium diphosphate
relationship: RO:0002309 CHEBI:71240 ! has exposure stimulus sodium diphosphate

[Term]
id: ECTO:9001610
name: exposure to N-methyl-N-picrylnitramine
def: "An exposure to N-methyl-N-picrylnitramine." []
synonym: "N-methyl-N-picrylnitramine exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28950 ! has exposure stimulus N-methyl-N-picrylnitramine
relationship: RO:0002309 CHEBI:28950 ! has exposure stimulus N-methyl-N-picrylnitramine

[Term]
id: ECTO:9001611
name: exposure to p-toluidine
def: "An exposure to p-toluidine." []
synonym: "p-toluidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37825 ! has exposure stimulus p-toluidine
relationship: RO:0002309 CHEBI:37825 ! has exposure stimulus p-toluidine

[Term]
id: ECTO:9001612
name: exposure to trichloroacetic acid
def: "An exposure to trichloroacetic acid." []
synonym: "trichloroacetic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30956 ! has exposure stimulus trichloroacetic acid
relationship: RO:0002309 CHEBI:30956 ! has exposure stimulus trichloroacetic acid

[Term]
id: ECTO:9001613
name: exposure to 2,4,6-trinitrotoluene
def: "An exposure to 2,4,6-trinitrotoluene." []
synonym: "2,4,6-trinitrotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46053 ! has exposure stimulus 2,4,6-trinitrotoluene
relationship: RO:0002309 CHEBI:46053 ! has exposure stimulus 2,4,6-trinitrotoluene

[Term]
id: ECTO:9001614
name: exposure to pentanal
def: "An exposure to pentanal." []
synonym: "pentanal exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84069 ! has exposure stimulus pentanal
relationship: RO:0002309 CHEBI:84069 ! has exposure stimulus pentanal

[Term]
id: ECTO:9001615
name: exposure to 4-vinylcyclohexene dioxide
def: "An exposure to 4-vinylcyclohexene dioxide." []
synonym: "4-vinylcyclohexene dioxide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59001 ! has exposure stimulus 4-vinylcyclohexene dioxide
relationship: RO:0002309 CHEBI:59001 ! has exposure stimulus 4-vinylcyclohexene dioxide

[Term]
id: ECTO:9001616
name: exposure to Vinylidene fluoride
def: "An exposure to Vinylidene fluoride." []
synonym: "Vinylidene fluoride exposure" EXACT []
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82550 ! has exposure stimulus Vinylidene fluoride
relationship: RO:0002309 CHEBI:82550 ! has exposure stimulus Vinylidene fluoride

[Term]
id: ECTO:9001617
name: exposure to zirconium
def: "An exposure to zirconium atom." []
synonym: "zirconium atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33342 ! has exposure stimulus zirconium atom
relationship: RO:0002309 CHEBI:33342 ! has exposure stimulus zirconium atom

[Term]
id: ECTO:9001618
name: exposure to Soman
def: "An exposure to Soman." []
synonym: "Soman exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9195 ! has exposure stimulus Soman
relationship: RO:0002309 CHEBI:9195 ! has exposure stimulus Soman

[Term]
id: ECTO:9001619
name: exposure to polybromodiphenyl ether
def: "An exposure to polybromodiphenyl ether." []
synonym: "polybromodiphenyl ether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002162 ! exposure to brominated flame retardant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134094 ! has exposure stimulus polybromodiphenyl ether
relationship: RO:0002309 CHEBI:134094 ! has exposure stimulus polybromodiphenyl ether

[Term]
id: ECTO:9001620
name: exposure to perfluorinated compound
def: "An exposure to perfluorinated compound." []
synonym: "perfluorinated compound exposure" EXACT []
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134091 ! has exposure stimulus perfluorinated compound
relationship: RO:0002309 CHEBI:134091 ! has exposure stimulus perfluorinated compound

[Term]
id: ECTO:9001621
name: exposure to volatile organic compound
def: "An exposure to volatile organic compound." []
synonym: "volatile organic compound exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134179 ! has exposure stimulus volatile organic compound
relationship: RO:0002309 CHEBI:134179 ! has exposure stimulus volatile organic compound

[Term]
id: ECTO:9001622
name: exposure to perfluorobutanesulfonic acid
def: "An exposure to perfluorobutanesulfonic acid." []
synonym: "perfluorobutanesulfonic acid exposure" EXACT []
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132446 ! has exposure stimulus perfluorobutanesulfonic acid
relationship: RO:0002309 CHEBI:132446 ! has exposure stimulus perfluorobutanesulfonic acid

[Term]
id: ECTO:9001623
name: exposure to perfluorohexanesulfonic acid
def: "An exposure to perfluorohexanesulfonic acid." []
synonym: "perfluorohexanesulfonic acid exposure" EXACT []
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132448 ! has exposure stimulus perfluorohexanesulfonic acid
relationship: RO:0002309 CHEBI:132448 ! has exposure stimulus perfluorohexanesulfonic acid

[Term]
id: ECTO:9001624
name: exposure to arsenocholine
def: "An exposure to arsenocholine." []
synonym: "arsenocholine exposure" EXACT []
is_a: ECTO:9000534 ! exposure to organoarsenic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134092 ! has exposure stimulus arsenocholine
relationship: RO:0002309 CHEBI:134092 ! has exposure stimulus arsenocholine

[Term]
id: ECTO:9001625
name: exposure to polychlorinated dibenzodioxine
def: "An exposure to polychlorinated dibenzodioxine." []
synonym: "polychlorinated dibenzodioxine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001537 ! exposure to polychlorinated dibenzodioxines and related compounds
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36682 ! has exposure stimulus polychlorinated dibenzodioxine
relationship: RO:0002309 CHEBI:36682 ! has exposure stimulus polychlorinated dibenzodioxine

[Term]
id: ECTO:9001626
name: exposure to 1,3-dichloropropane
def: "An exposure to 1,3-dichloropropane." []
synonym: "1,3-dichloropropane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:137978 ! has exposure stimulus 1,3-dichloropropane
relationship: RO:0002309 CHEBI:137978 ! has exposure stimulus 1,3-dichloropropane

[Term]
id: ECTO:9001627
name: exposure to inorganic acid
def: "An exposure to inorganic acid." []
synonym: "inorganic acid exposure" EXACT []
is_a: ECTO:0000650 ! exposure to Bronsted acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138103 ! has exposure stimulus inorganic acid
relationship: RO:0002309 CHEBI:138103 ! has exposure stimulus inorganic acid

[Term]
id: ECTO:9001628
name: exposure to gas molecular entity
def: "An exposure to gas molecular entity." []
synonym: "gas molecular entity exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138675 ! has exposure stimulus gas molecular entity
relationship: RO:0002309 CHEBI:138675 ! has exposure stimulus gas molecular entity

[Term]
id: ECTO:9001629
name: exposure to 2-bromophenyl 2,4-dibromophenyl ether
def: "An exposure to 2-bromophenyl 2,4-dibromophenyl ether." []
synonym: "2-bromophenyl 2,4-dibromophenyl ether exposure" EXACT []
is_a: ECTO:9001619 ! exposure to polybromodiphenyl ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138001 ! has exposure stimulus 2-bromophenyl 2,4-dibromophenyl ether
relationship: RO:0002309 CHEBI:138001 ! has exposure stimulus 2-bromophenyl 2,4-dibromophenyl ether

[Term]
id: ECTO:9001630
name: exposure to endocrine disruptor
def: "An exposure to endocrine disruptor." []
synonym: "endocrine disruptor exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138015 ! has exposure stimulus endocrine disruptor
relationship: RO:0002309 CHEBI:138015 ! has exposure stimulus endocrine disruptor

[Term]
id: ECTO:9001631
name: exposure to metalloid
def: "An exposure to metalloid atom." []
synonym: "metalloid atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:137980 ! has exposure stimulus metalloid atom
relationship: RO:0002309 CHEBI:137980 ! has exposure stimulus metalloid atom

[Term]
id: ECTO:9001632
name: exposure to 4-bromophenyl 2,4-dibromophenyl ether
def: "An exposure to 4-bromophenyl 2,4-dibromophenyl ether." []
synonym: "4-bromophenyl 2,4-dibromophenyl ether exposure" EXACT []
is_a: ECTO:9001619 ! exposure to polybromodiphenyl ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138036 ! has exposure stimulus 4-bromophenyl 2,4-dibromophenyl ether
relationship: RO:0002309 CHEBI:138036 ! has exposure stimulus 4-bromophenyl 2,4-dibromophenyl ether

[Term]
id: ECTO:9001633
name: exposure to 2,4-dibromophenyl 3,4-dibromophenyl ether
def: "An exposure to 2,4-dibromophenyl 3,4-dibromophenyl ether." []
synonym: "2,4-dibromophenyl 3,4-dibromophenyl ether exposure" EXACT []
is_a: ECTO:9001619 ! exposure to polybromodiphenyl ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138038 ! has exposure stimulus 2,4-dibromophenyl 3,4-dibromophenyl ether
relationship: RO:0002309 CHEBI:138038 ! has exposure stimulus 2,4-dibromophenyl 3,4-dibromophenyl ether

[Term]
id: ECTO:9001634
name: exposure to 2,4-dibromophenyl 2,3,4-tribromophenyl ether
def: "An exposure to 2,4-dibromophenyl 2,3,4-tribromophenyl ether." []
synonym: "2,4-dibromophenyl 2,3,4-tribromophenyl ether exposure" EXACT []
is_a: ECTO:9001619 ! exposure to polybromodiphenyl ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138064 ! has exposure stimulus 2,4-dibromophenyl 2,3,4-tribromophenyl ether
relationship: RO:0002309 CHEBI:138064 ! has exposure stimulus 2,4-dibromophenyl 2,3,4-tribromophenyl ether

[Term]
id: ECTO:9001635
name: exposure to 2,4-dibromophenyl 2,4,6-tribromophenyl ether
def: "An exposure to 2,4-dibromophenyl 2,4,6-tribromophenyl ether." []
synonym: "2,4-dibromophenyl 2,4,6-tribromophenyl ether exposure" EXACT []
is_a: ECTO:9001619 ! exposure to polybromodiphenyl ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138065 ! has exposure stimulus 2,4-dibromophenyl 2,4,6-tribromophenyl ether
relationship: RO:0002309 CHEBI:138065 ! has exposure stimulus 2,4-dibromophenyl 2,4,6-tribromophenyl ether

[Term]
id: ECTO:9001636
name: exposure to 2,2',4,4',5,5'-hexabromobiphenyl
def: "An exposure to 2,2',4,4',5,5'-hexabromobiphenyl." []
synonym: "2,2',4,4',5,5'-hexabromobiphenyl exposure" EXACT []
is_a: ECTO:9001538 ! exposure to polybromobiphenyl
is_a: ECTO:9002162 ! exposure to brominated flame retardant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134050 ! has exposure stimulus 2,2',4,4',5,5'-hexabromobiphenyl
relationship: RO:0002309 CHEBI:134050 ! has exposure stimulus 2,2',4,4',5,5'-hexabromobiphenyl

[Term]
id: ECTO:9001637
name: exposure to perfluorooctanesulfonamide
def: "An exposure to perfluorooctanesulfonamide." []
synonym: "perfluorooctanesulfonamide exposure" EXACT []
is_a: ECTO:9001359 ! exposure to sulfonamide
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138089 ! has exposure stimulus perfluorooctanesulfonamide
relationship: RO:0002309 CHEBI:138089 ! has exposure stimulus perfluorooctanesulfonamide

[Term]
id: ECTO:9001638
name: exposure to trimethylarsine oxide
def: "An exposure to trimethylarsine oxide." []
synonym: "trimethylarsine oxide exposure" EXACT []
is_a: ECTO:9000032 ! exposure to arsenic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27131 ! has exposure stimulus trimethylarsine oxide
relationship: RO:0002309 CHEBI:27131 ! has exposure stimulus trimethylarsine oxide

[Term]
id: ECTO:9001639
name: exposure to EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
def: "An exposure to EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor." []
synonym: "EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:131699 ! has exposure stimulus EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
relationship: RO:0002309 CHEBI:131699 ! has exposure stimulus EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor

[Term]
id: ECTO:9001640
name: exposure to electron donor
def: "An exposure to electron donor." []
synonym: "electron donor exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15022 ! has exposure stimulus electron donor
relationship: RO:0002309 CHEBI:15022 ! has exposure stimulus electron donor

[Term]
id: ECTO:9001641
name: exposure to electron acceptor
def: "An exposure to electron acceptor." []
synonym: "electron acceptor exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17654 ! has exposure stimulus electron acceptor
relationship: RO:0002309 CHEBI:17654 ! has exposure stimulus electron acceptor

[Term]
id: ECTO:9001642
name: exposure to EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor
def: "An exposure to EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor." []
synonym: "EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:20569 ! has exposure stimulus EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor
relationship: RO:0002309 CHEBI:20569 ! has exposure stimulus EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor

[Term]
id: ECTO:9001643
name: obsolete vitamin C exposure
is_obsolete: true
replaced_by: ECTO:9000143

[Term]
id: ECTO:9001644
name: exposure to acaricide
def: "An exposure to acaricide." []
synonym: "acaricide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22153 ! has exposure stimulus acaricide
relationship: RO:0002309 CHEBI:22153 ! has exposure stimulus acaricide

[Term]
id: ECTO:9001645
name: exposure to EC 2.2.1.6 (acetolactate synthase) inhibitor
def: "An exposure to EC 2.2.1.6 (acetolactate synthase) inhibitor." []
synonym: "EC 2.2.1.6 (acetolactate synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22180 ! has exposure stimulus EC 2.2.1.6 (acetolactate synthase) inhibitor
relationship: RO:0002309 CHEBI:22180 ! has exposure stimulus EC 2.2.1.6 (acetolactate synthase) inhibitor

[Term]
id: ECTO:9001647
name: exposure to antioxidant
def: "An exposure to antioxidant." []
synonym: "antioxidant exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22586 ! has exposure stimulus antioxidant
relationship: RO:0002309 CHEBI:22586 ! has exposure stimulus antioxidant

[Term]
id: ECTO:9001648
name: exposure to antiviral agent
def: "An exposure to antiviral agent." []
synonym: "antiviral agent exposure" EXACT []
is_a: ECTO:0000544 ! exposure to antimicrobial agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22587 ! has exposure stimulus antiviral agent
relationship: RO:0002309 CHEBI:22587 ! has exposure stimulus antiviral agent

[Term]
id: ECTO:9001649
name: exposure to auxin
def: "An exposure to auxin." []
synonym: "auxin exposure" EXACT []
is_a: ECTO:9001766 ! exposure to plant hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22676 ! has exposure stimulus auxin
relationship: RO:0002309 CHEBI:22676 ! has exposure stimulus auxin

[Term]
id: ECTO:9001650
name: exposure to phytogenic insecticide
def: "An exposure to phytogenic insecticide." []
synonym: "phytogenic insecticide exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22917 ! has exposure stimulus phytogenic insecticide
relationship: RO:0002309 CHEBI:22917 ! has exposure stimulus phytogenic insecticide

[Term]
id: ECTO:9001651
name: exposure to calcium ionophore
def: "An exposure to calcium ionophore." []
synonym: "calcium ionophore exposure" EXACT []
is_a: ECTO:9001669 ! exposure to ionophore
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22986 ! has exposure stimulus calcium ionophore
relationship: RO:0002309 CHEBI:22986 ! has exposure stimulus calcium ionophore

[Term]
id: ECTO:9001652
name: exposure to EC 4.2.1.1 (carbonic anhydrase) inhibitor
def: "An exposure to EC 4.2.1.1 (carbonic anhydrase) inhibitor." []
synonym: "EC 4.2.1.1 (carbonic anhydrase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23018 ! has exposure stimulus EC 4.2.1.1 (carbonic anhydrase) inhibitor
relationship: RO:0002309 CHEBI:23018 ! has exposure stimulus EC 4.2.1.1 (carbonic anhydrase) inhibitor

[Term]
id: ECTO:9001653
name: exposure to chromophore
def: "An exposure to chromophore." []
synonym: "chromophore exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23240 ! has exposure stimulus chromophore
relationship: RO:0002309 CHEBI:23240 ! has exposure stimulus chromophore

[Term]
id: ECTO:9001654
name: exposure to coenzyme
def: "An exposure to coenzyme." []
synonym: "coenzyme exposure" EXACT []
is_a: ECTO:9001655 ! exposure to cofactor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23354 ! has exposure stimulus coenzyme
relationship: RO:0002309 CHEBI:23354 ! has exposure stimulus coenzyme

[Term]
id: ECTO:9001655
name: exposure to cofactor
def: "An exposure to cofactor." []
synonym: "cofactor exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23357 ! has exposure stimulus cofactor
relationship: RO:0002309 CHEBI:23357 ! has exposure stimulus cofactor

[Term]
id: ECTO:9001656
name: exposure to compatible osmolytes
def: "An exposure to compatible osmolytes." []
synonym: "compatible osmolytes exposure" EXACT []
is_a: ECTO:9001678 ! exposure to osmolyte
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23366 ! has exposure stimulus compatible osmolytes
relationship: RO:0002309 CHEBI:23366 ! has exposure stimulus compatible osmolytes

[Term]
id: ECTO:9001657
name: exposure to cytokinin
def: "An exposure to cytokinin." []
synonym: "cytokinin exposure" EXACT []
is_a: ECTO:9001766 ! exposure to plant hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23530 ! has exposure stimulus cytokinin
relationship: RO:0002309 CHEBI:23530 ! has exposure stimulus cytokinin

[Term]
id: ECTO:9001658
name: exposure to defoliant
def: "An exposure to defoliant." []
synonym: "defoliant exposure" EXACT []
is_a: ECTO:0000515 ! exposure to herbicide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23582 ! has exposure stimulus defoliant
relationship: RO:0002309 CHEBI:23582 ! has exposure stimulus defoliant

[Term]
id: ECTO:9001660
name: exposure to ethylene releasers
def: "An exposure to ethylene releasers." []
synonym: "ethylene releasers exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24002 ! has exposure stimulus ethylene releasers
relationship: RO:0002309 CHEBI:24002 ! has exposure stimulus ethylene releasers

[Term]
id: ECTO:9001661
name: exposure to fat-soluble vitamin
def: "An exposure to fat-soluble vitamin (role)." []
synonym: "fat-soluble vitamin (role) exposure" EXACT []
is_a: ECTO:9001691 ! exposure to vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24020 ! has exposure stimulus fat-soluble vitamin (role)
relationship: RO:0002309 CHEBI:24020 ! has exposure stimulus fat-soluble vitamin (role)

[Term]
id: ECTO:9001662
name: exposure to iron(3+) chelator
def: "An exposure to iron(3+) chelator." []
synonym: "iron(3+) chelator exposure" EXACT []
is_a: ECTO:9001779 ! exposure to iron chelator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24028 ! has exposure stimulus iron(3+) chelator
relationship: RO:0002309 CHEBI:24028 ! has exposure stimulus iron(3+) chelator

[Term]
id: ECTO:9001664
name: exposure to EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
def: "An exposure to EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor." []
synonym: "EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24319 ! has exposure stimulus EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor
relationship: RO:0002309 CHEBI:24319 ! has exposure stimulus EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor

[Term]
id: ECTO:9001668
name: exposure to intercalator
def: "An exposure to intercalator." []
synonym: "intercalator exposure" EXACT []
is_a: ECTO:0000523 ! exposure to mutagen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24853 ! has exposure stimulus intercalator
relationship: RO:0002309 CHEBI:24853 ! has exposure stimulus intercalator

[Term]
id: ECTO:9001669
name: exposure to ionophore
def: "An exposure to ionophore." []
synonym: "ionophore exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24869 ! has exposure stimulus ionophore
relationship: RO:0002309 CHEBI:24869 ! has exposure stimulus ionophore

[Term]
id: ECTO:9001670
name: exposure to jasmonates
def: "An exposure to jasmonates." []
synonym: "jasmonates exposure" EXACT []
is_a: ECTO:9001766 ! exposure to plant hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24937 ! has exposure stimulus jasmonates
relationship: RO:0002309 CHEBI:24937 ! has exposure stimulus jasmonates

[Term]
id: ECTO:9001674
name: exposure to nematicide
def: "An exposure to nematicide." []
synonym: "nematicide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25491 ! has exposure stimulus nematicide
relationship: RO:0002309 CHEBI:25491 ! has exposure stimulus nematicide

[Term]
id: ECTO:9001676
name: exposure to neonicotinoid insectide
def: "An exposure to neonicotinoid insectide." []
synonym: "neonicotinoid insectide exposure" EXACT []
is_a: ECTO:0000730 ! exposure to neurotoxin
is_a: ECTO:9000089 ! exposure to insecticide
is_a: ECTO:9001803 ! exposure to nicotinic acetylcholine receptor agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25540 ! has exposure stimulus neonicotinoid insectide
relationship: RO:0002309 CHEBI:25540 ! has exposure stimulus neonicotinoid insectide

[Term]
id: ECTO:9001677
name: exposure to nucleoside antibiotic
def: "An exposure to nucleoside antibiotic." []
synonym: "nucleoside antibiotic exposure" EXACT []
is_a: ECTO:0000544 ! exposure to antimicrobial agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25605 ! has exposure stimulus nucleoside antibiotic
relationship: RO:0002309 CHEBI:25605 ! has exposure stimulus nucleoside antibiotic

[Term]
id: ECTO:9001678
name: exposure to osmolyte
def: "An exposure to osmolyte." []
synonym: "osmolyte exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25728 ! has exposure stimulus osmolyte
relationship: RO:0002309 CHEBI:25728 ! has exposure stimulus osmolyte

[Term]
id: ECTO:9001680
name: exposure to pheromone
def: "An exposure to pheromone." []
synonym: "pheromone exposure" EXACT []
is_a: ECTO:0000543 ! exposure to molecular messenger
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26013 ! has exposure stimulus pheromone
relationship: RO:0002309 CHEBI:26013 ! has exposure stimulus pheromone

[Term]
id: ECTO:9001681
name: exposure to phytoalexin
def: "An exposure to phytoalexin." []
synonym: "phytoalexin exposure" EXACT []
is_a: ECTO:9001782 ! exposure to phytotoxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26115 ! has exposure stimulus phytoalexin
relationship: RO:0002309 CHEBI:26115 ! has exposure stimulus phytoalexin

[Term]
id: ECTO:9001682
name: exposure to biological pigment
def: "An exposure to biological pigment." []
synonym: "biological pigment exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26130 ! has exposure stimulus biological pigment
relationship: RO:0002309 CHEBI:26130 ! has exposure stimulus biological pigment

[Term]
id: ECTO:9001683
name: exposure to prosthetic group
def: "An exposure to prosthetic group." []
synonym: "prosthetic group exposure" EXACT []
is_a: ECTO:9001655 ! exposure to cofactor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26348 ! has exposure stimulus prosthetic group
relationship: RO:0002309 CHEBI:26348 ! has exposure stimulus prosthetic group

[Term]
id: ECTO:9001684
name: exposure to siderophore
def: "An exposure to siderophore." []
synonym: "siderophore exposure" EXACT []
is_a: ECTO:9001655 ! exposure to cofactor
is_a: ECTO:9001662 ! exposure to iron(3+) chelator
is_a: ECTO:9001669 ! exposure to ionophore
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26672 ! has exposure stimulus siderophore
relationship: RO:0002309 CHEBI:26672 ! has exposure stimulus siderophore

[Term]
id: ECTO:9001685
name: exposure to synthetic auxin
def: "An exposure to synthetic auxin." []
synonym: "synthetic auxin exposure" EXACT []
is_a: ECTO:9001649 ! exposure to auxin
is_a: ECTO:9001746 ! exposure to xenobiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26841 ! has exposure stimulus synthetic auxin
relationship: RO:0002309 CHEBI:26841 ! has exposure stimulus synthetic auxin

[Term]
id: ECTO:9001687
name: exposure to micronutrient
def: "An exposure to micronutrient." []
synonym: "micronutrient exposure" EXACT []
is_a: ECTO:9001695 ! exposure to nutrient
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27027 ! has exposure stimulus micronutrient
relationship: RO:0002309 CHEBI:27027 ! has exposure stimulus micronutrient

[Term]
id: ECTO:9001688
name: exposure to volatile oil component
def: "An exposure to volatile oil component." []
synonym: "volatile oil component exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27311 ! has exposure stimulus volatile oil component
relationship: RO:0002309 CHEBI:27311 ! has exposure stimulus volatile oil component

[Term]
id: ECTO:9001689
name: exposure to water-soluble vitamin
def: "An exposure to water-soluble vitamin (role)." []
synonym: "water-soluble vitamin (role) exposure" EXACT []
is_a: ECTO:9001691 ! exposure to vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27314 ! has exposure stimulus water-soluble vitamin (role)
relationship: RO:0002309 CHEBI:27314 ! has exposure stimulus water-soluble vitamin (role)

[Term]
id: ECTO:9001690
name: exposure to detergent
def: "An exposure to detergent." []
synonym: "detergent exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27780 ! has exposure stimulus detergent
relationship: RO:0002309 CHEBI:27780 ! has exposure stimulus detergent

[Term]
id: ECTO:9001691
name: exposure to vitamin
def: "An exposure to vitamin (role)." []
synonym: "vitamin (role) exposure" EXACT []
is_a: ECTO:9001687 ! exposure to micronutrient
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33229 ! has exposure stimulus vitamin (role)
relationship: RO:0002309 CHEBI:33229 ! has exposure stimulus vitamin (role)

[Term]
id: ECTO:9001694
name: exposure to antibacterial agent
def: "An exposure to antibacterial agent." []
synonym: "antibacterial agent exposure" EXACT []
is_a: ECTO:0000544 ! exposure to antimicrobial agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33282 ! has exposure stimulus antibacterial agent
relationship: RO:0002309 CHEBI:33282 ! has exposure stimulus antibacterial agent

[Term]
id: ECTO:9001695
name: exposure to nutrient
def: "An exposure to nutrient." []
synonym: "nutrient exposure" EXACT []
is_a: ECTO:9002063 ! exposure to food component
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33284 ! has exposure stimulus nutrient
relationship: RO:0002309 CHEBI:33284 ! has exposure stimulus nutrient

[Term]
id: ECTO:9001696
name: exposure to agrochemical
def: "An exposure to agrochemical." []
synonym: "agrochemical exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33286 ! has exposure stimulus agrochemical
relationship: RO:0002309 CHEBI:33286 ! has exposure stimulus agrochemical

[Term]
id: ECTO:9001698
name: exposure to avicide
def: "An exposure to avicide." []
synonym: "avicide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33289 ! has exposure stimulus avicide
relationship: RO:0002309 CHEBI:33289 ! has exposure stimulus avicide

[Term]
id: ECTO:9001699
name: exposure to fuel
def: "An exposure to fuel." []
synonym: "fuel exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33292 ! has exposure stimulus fuel
relationship: RO:0002309 CHEBI:33292 ! has exposure stimulus fuel

[Term]
id: ECTO:9001700
name: exposure to diagnostic agent
def: "An exposure to diagnostic agent." []
synonym: "diagnostic agent exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33295 ! has exposure stimulus diagnostic agent
relationship: RO:0002309 CHEBI:33295 ! has exposure stimulus diagnostic agent

[Term]
id: ECTO:9001701
name: exposure to reagent
def: "An exposure to reagent." []
synonym: "reagent exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33893 ! has exposure stimulus reagent
relationship: RO:0002309 CHEBI:33893 ! has exposure stimulus reagent

[Term]
id: ECTO:9001702
name: exposure to macronutrient
def: "An exposure to macronutrient." []
synonym: "macronutrient exposure" EXACT []
is_a: ECTO:9001695 ! exposure to nutrient
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33937 ! has exposure stimulus macronutrient
relationship: RO:0002309 CHEBI:33937 ! has exposure stimulus macronutrient

[Term]
id: ECTO:9001703
name: exposure to tracer
def: "An exposure to tracer." []
synonym: "tracer exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35204 ! has exposure stimulus tracer
relationship: RO:0002309 CHEBI:35204 ! has exposure stimulus tracer

[Term]
id: ECTO:9001704
name: exposure to plant growth retardant
def: "An exposure to plant growth retardant." []
synonym: "plant growth retardant exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35219 ! has exposure stimulus plant growth retardant
relationship: RO:0002309 CHEBI:35219 ! has exposure stimulus plant growth retardant

[Term]
id: ECTO:9001705
name: exposure to antimetabolite
def: "An exposure to antimetabolite." []
synonym: "antimetabolite exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35221 ! has exposure stimulus antimetabolite
relationship: RO:0002309 CHEBI:35221 ! has exposure stimulus antimetabolite

[Term]
id: ECTO:9001707
name: exposure to catalyst
def: "An exposure to catalyst." []
synonym: "catalyst exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35223 ! has exposure stimulus catalyst
relationship: RO:0002309 CHEBI:35223 ! has exposure stimulus catalyst

[Term]
id: ECTO:9001708
name: exposure to effector
def: "An exposure to effector." []
synonym: "effector exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35224 ! has exposure stimulus effector
relationship: RO:0002309 CHEBI:35224 ! has exposure stimulus effector

[Term]
id: ECTO:9001709
name: exposure to fossil fuel
def: "An exposure to fossil fuel." []
synonym: "fossil fuel exposure" EXACT []
is_a: ECTO:9001699 ! exposure to fuel
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35230 ! has exposure stimulus fossil fuel
relationship: RO:0002309 CHEBI:35230 ! has exposure stimulus fossil fuel

[Term]
id: ECTO:9001710
name: exposure to central nervous system stimulant
def: "An exposure to central nervous system stimulant." []
synonym: "central nervous system stimulant exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35337 ! has exposure stimulus central nervous system stimulant
relationship: RO:0002309 CHEBI:35337 ! has exposure stimulus central nervous system stimulant

[Term]
id: ECTO:9001711
name: exposure to antiinfective agent
def: "An exposure to antiinfective agent." []
synonym: "antiinfective agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35441 ! has exposure stimulus antiinfective agent
relationship: RO:0002309 CHEBI:35441 ! has exposure stimulus antiinfective agent

[Term]
id: ECTO:9001712
name: exposure to antiparasitic agent
def: "An exposure to antiparasitic agent." []
synonym: "antiparasitic agent exposure" EXACT []
is_a: ECTO:9001711 ! exposure to antiinfective agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35442 ! has exposure stimulus antiparasitic agent
relationship: RO:0002309 CHEBI:35442 ! has exposure stimulus antiparasitic agent

[Term]
id: ECTO:9001713
name: exposure to anthelminthic drug
def: "An exposure to anthelminthic drug." []
synonym: "anthelminthic drug exposure" EXACT []
is_a: ECTO:9001712 ! exposure to antiparasitic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35443 ! has exposure stimulus anthelminthic drug
relationship: RO:0002309 CHEBI:35443 ! has exposure stimulus anthelminthic drug

[Term]
id: ECTO:9001714
name: exposure to antinematodal drug
def: "An exposure to antinematodal drug." []
synonym: "antinematodal drug exposure" EXACT []
is_a: ECTO:9001674 ! exposure to nematicide
is_a: ECTO:9001713 ! exposure to anthelminthic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35444 ! has exposure stimulus antinematodal drug
relationship: RO:0002309 CHEBI:35444 ! has exposure stimulus antinematodal drug

[Term]
id: ECTO:9001715
name: exposure to EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
def: "An exposure to EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor." []
synonym: "EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
is_a: ECTO:9001744 ! exposure to antihypertensive agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35457 ! has exposure stimulus EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
relationship: RO:0002309 CHEBI:35457 ! has exposure stimulus EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor

[Term]
id: ECTO:9001716
name: exposure to antidepressant
def: "An exposure to antidepressant." []
synonym: "antidepressant exposure" EXACT []
is_a: ECTO:9001717 ! exposure to psychotropic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35469 ! has exposure stimulus antidepressant
relationship: RO:0002309 CHEBI:35469 ! has exposure stimulus antidepressant

[Term]
id: ECTO:9001717
name: exposure to psychotropic drug
def: "An exposure to psychotropic drug." []
synonym: "psychotropic drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35471 ! has exposure stimulus psychotropic drug
relationship: RO:0002309 CHEBI:35471 ! has exposure stimulus psychotropic drug

[Term]
id: ECTO:9001718
name: exposure to anti-inflammatory drug
def: "An exposure to anti-inflammatory drug." []
synonym: "anti-inflammatory drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:9001982 ! exposure to anti-inflammatory agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35472 ! has exposure stimulus anti-inflammatory drug
relationship: RO:0002309 CHEBI:35472 ! has exposure stimulus anti-inflammatory drug

[Term]
id: ECTO:9001719
name: exposure to anxiolytic drug
def: "An exposure to anxiolytic drug." []
synonym: "anxiolytic drug exposure" EXACT []
is_a: ECTO:9001717 ! exposure to psychotropic drug
is_a: ECTO:9001726 ! exposure to central nervous system depressant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35474 ! has exposure stimulus anxiolytic drug
relationship: RO:0002309 CHEBI:35474 ! has exposure stimulus anxiolytic drug

[Term]
id: ECTO:9001720
name: exposure to non-steroidal anti-inflammatory drug
def: "An exposure to non-steroidal anti-inflammatory drug." []
synonym: "non-steroidal anti-inflammatory drug exposure" EXACT []
is_a: ECTO:9001718 ! exposure to anti-inflammatory drug
is_a: ECTO:9001753 ! exposure to antirheumatic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35475 ! has exposure stimulus non-steroidal anti-inflammatory drug
relationship: RO:0002309 CHEBI:35475 ! has exposure stimulus non-steroidal anti-inflammatory drug

[Term]
id: ECTO:9001721
name: exposure to antipsychotic agent
def: "An exposure to antipsychotic agent." []
synonym: "antipsychotic agent exposure" EXACT []
is_a: ECTO:9001717 ! exposure to psychotropic drug
is_a: ECTO:9001726 ! exposure to central nervous system depressant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35476 ! has exposure stimulus antipsychotic agent
relationship: RO:0002309 CHEBI:35476 ! has exposure stimulus antipsychotic agent

[Term]
id: ECTO:9001722
name: exposure to analgesic
def: "An exposure to analgesic." []
synonym: "analgesic exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35480 ! has exposure stimulus analgesic
relationship: RO:0002309 CHEBI:35480 ! has exposure stimulus analgesic

[Term]
id: ECTO:9001723
name: exposure to non-narcotic analgesic
def: "An exposure to non-narcotic analgesic." []
synonym: "non-narcotic analgesic exposure" EXACT []
is_a: ECTO:9001722 ! exposure to analgesic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35481 ! has exposure stimulus non-narcotic analgesic
relationship: RO:0002309 CHEBI:35481 ! has exposure stimulus non-narcotic analgesic

[Term]
id: ECTO:9001724
name: exposure to opioid analgesic
def: "An exposure to opioid analgesic." []
synonym: "opioid analgesic exposure" EXACT []
is_a: ECTO:9001722 ! exposure to analgesic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35482 ! has exposure stimulus opioid analgesic
relationship: RO:0002309 CHEBI:35482 ! has exposure stimulus opioid analgesic

[Term]
id: ECTO:9001725
name: exposure to EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
def: "An exposure to EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor." []
synonym: "EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35487 ! has exposure stimulus EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
relationship: RO:0002309 CHEBI:35487 ! has exposure stimulus EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor

[Term]
id: ECTO:9001726
name: exposure to central nervous system depressant
def: "An exposure to central nervous system depressant." []
synonym: "central nervous system depressant exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35488 ! has exposure stimulus central nervous system depressant
relationship: RO:0002309 CHEBI:35488 ! has exposure stimulus central nervous system depressant

[Term]
id: ECTO:9001727
name: exposure to antipyretic
def: "An exposure to antipyretic." []
synonym: "antipyretic exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35493 ! has exposure stimulus antipyretic
relationship: RO:0002309 CHEBI:35493 ! has exposure stimulus antipyretic

[Term]
id: ECTO:9001728
name: exposure to diuretic
def: "An exposure to diuretic." []
synonym: "diuretic exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35498 ! has exposure stimulus diuretic
relationship: RO:0002309 CHEBI:35498 ! has exposure stimulus diuretic

[Term]
id: ECTO:9001729
name: exposure to hallucinogen
def: "An exposure to hallucinogen." []
synonym: "hallucinogen exposure" EXACT []
is_a: ECTO:9001717 ! exposure to psychotropic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35499 ! has exposure stimulus hallucinogen
relationship: RO:0002309 CHEBI:35499 ! has exposure stimulus hallucinogen

[Term]
id: ECTO:9001730
name: exposure to beta-adrenergic agonist
def: "An exposure to beta-adrenergic agonist." []
synonym: "beta-adrenergic agonist exposure" EXACT []
is_a: ECTO:9001773 ! exposure to adrenergic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35522 ! has exposure stimulus beta-adrenergic agonist
relationship: RO:0002309 CHEBI:35522 ! has exposure stimulus beta-adrenergic agonist

[Term]
id: ECTO:9001731
name: exposure to bronchodilator agent
def: "An exposure to bronchodilator agent." []
synonym: "bronchodilator agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35523 ! has exposure stimulus bronchodilator agent
relationship: RO:0002309 CHEBI:35523 ! has exposure stimulus bronchodilator agent

[Term]
id: ECTO:9001732
name: exposure to sympathomimetic agent
def: "An exposure to sympathomimetic agent." []
synonym: "sympathomimetic agent exposure" EXACT []
is_a: ECTO:9001773 ! exposure to adrenergic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35524 ! has exposure stimulus sympathomimetic agent
relationship: RO:0002309 CHEBI:35524 ! has exposure stimulus sympathomimetic agent

[Term]
id: ECTO:9001733
name: exposure to hypoglycemic agent
def: "An exposure to hypoglycemic agent." []
synonym: "hypoglycemic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35526 ! has exposure stimulus hypoglycemic agent
relationship: RO:0002309 CHEBI:35526 ! has exposure stimulus hypoglycemic agent

[Term]
id: ECTO:9001734
name: exposure to beta-adrenergic antagonist
def: "An exposure to beta-adrenergic antagonist." []
synonym: "beta-adrenergic antagonist exposure" EXACT []
is_a: ECTO:9001767 ! exposure to adrenergic antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35530 ! has exposure stimulus beta-adrenergic antagonist
relationship: RO:0002309 CHEBI:35530 ! has exposure stimulus beta-adrenergic antagonist

[Term]
id: ECTO:9001735
name: exposure to EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
def: "An exposure to EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor." []
synonym: "EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35544 ! has exposure stimulus EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
relationship: RO:0002309 CHEBI:35544 ! has exposure stimulus EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor

[Term]
id: ECTO:9001736
name: exposure to EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
def: "An exposure to EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor." []
synonym: "EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35608 ! has exposure stimulus EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
relationship: RO:0002309 CHEBI:35608 ! has exposure stimulus EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor

[Term]
id: ECTO:9001737
name: exposure to antineoplastic agent
def: "An exposure to antineoplastic agent." []
synonym: "antineoplastic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35610 ! has exposure stimulus antineoplastic agent
relationship: RO:0002309 CHEBI:35610 ! has exposure stimulus antineoplastic agent

[Term]
id: ECTO:9001738
name: exposure to flavouring agent
def: "An exposure to flavouring agent." []
synonym: "flavouring agent exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35617 ! has exposure stimulus flavouring agent
relationship: RO:0002309 CHEBI:35617 ! has exposure stimulus flavouring agent

[Term]
id: ECTO:9001740
name: exposure to anticonvulsant
def: "An exposure to anticonvulsant." []
synonym: "anticonvulsant exposure" EXACT []
is_a: ECTO:9001726 ! exposure to central nervous system depressant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35623 ! has exposure stimulus anticonvulsant
relationship: RO:0002309 CHEBI:35623 ! has exposure stimulus anticonvulsant

[Term]
id: ECTO:9001741
name: exposure to EC 3.5.2.6 (beta-lactamase) inhibitor
def: "An exposure to EC 3.5.2.6 (beta-lactamase) inhibitor." []
synonym: "EC 3.5.2.6 (beta-lactamase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35625 ! has exposure stimulus EC 3.5.2.6 (beta-lactamase) inhibitor
relationship: RO:0002309 CHEBI:35625 ! has exposure stimulus EC 3.5.2.6 (beta-lactamase) inhibitor

[Term]
id: ECTO:9001742
name: exposure to adrenergic uptake inhibitor
def: "An exposure to adrenergic uptake inhibitor." []
synonym: "adrenergic uptake inhibitor exposure" EXACT []
is_a: ECTO:9001773 ! exposure to adrenergic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35640 ! has exposure stimulus adrenergic uptake inhibitor
relationship: RO:0002309 CHEBI:35640 ! has exposure stimulus adrenergic uptake inhibitor

[Term]
id: ECTO:9001743
name: exposure to hydroxymethylglutaryl-CoA reductase inhibitor
def: "An exposure to EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor." []
synonym: "EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35664 ! has exposure stimulus EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
relationship: RO:0002309 CHEBI:35664 ! has exposure stimulus EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor

[Term]
id: ECTO:9001744
name: exposure to antihypertensive agent
def: "An exposure to antihypertensive agent." []
synonym: "antihypertensive agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35674 ! has exposure stimulus antihypertensive agent
relationship: RO:0002309 CHEBI:35674 ! has exposure stimulus antihypertensive agent

[Term]
id: ECTO:9001745
name: exposure to antilipemic drug
def: "An exposure to antilipemic drug." []
synonym: "antilipemic drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35679 ! has exposure stimulus antilipemic drug
relationship: RO:0002309 CHEBI:35679 ! has exposure stimulus antilipemic drug

[Term]
id: ECTO:9001746
name: exposure to xenobiotic
def: "An exposure to xenobiotic." []
synonym: "xenobiotic exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35703 ! has exposure stimulus xenobiotic
relationship: RO:0002309 CHEBI:35703 ! has exposure stimulus xenobiotic

[Term]
id: ECTO:9001747
name: exposure to immunosuppressive agent
def: "An exposure to immunosuppressive agent." []
synonym: "immunosuppressive agent exposure" EXACT []
is_a: ECTO:9001869 ! exposure to immunomodulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35705 ! has exposure stimulus immunosuppressive agent
relationship: RO:0002309 CHEBI:35705 ! has exposure stimulus immunosuppressive agent

[Term]
id: ECTO:9001748
name: exposure to sedative
def: "An exposure to sedative." []
synonym: "sedative exposure" EXACT []
is_a: ECTO:9001726 ! exposure to central nervous system depressant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35717 ! has exposure stimulus sedative
relationship: RO:0002309 CHEBI:35717 ! has exposure stimulus sedative

[Term]
id: ECTO:9001749
name: exposure to antifungal agent
def: "An exposure to antifungal agent." []
synonym: "antifungal agent exposure" EXACT []
is_a: ECTO:0000544 ! exposure to antimicrobial agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35718 ! has exposure stimulus antifungal agent
relationship: RO:0002309 CHEBI:35718 ! has exposure stimulus antifungal agent

[Term]
id: ECTO:9001750
name: exposure to coccidiostat
def: "An exposure to coccidiostat." []
synonym: "coccidiostat exposure" EXACT []
is_a: ECTO:9001751 ! exposure to antiprotozoal drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35818 ! has exposure stimulus coccidiostat
relationship: RO:0002309 CHEBI:35818 ! has exposure stimulus coccidiostat

[Term]
id: ECTO:9001751
name: exposure to antiprotozoal drug
def: "An exposure to antiprotozoal drug." []
synonym: "antiprotozoal drug exposure" EXACT []
is_a: ECTO:9001712 ! exposure to antiparasitic agent
is_a: ECTO:9001755 ! exposure to antimicrobial drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35820 ! has exposure stimulus antiprotozoal drug
relationship: RO:0002309 CHEBI:35820 ! has exposure stimulus antiprotozoal drug

[Term]
id: ECTO:9001752
name: exposure to anticholesteremic drug
def: "An exposure to anticholesteremic drug." []
synonym: "anticholesteremic drug exposure" EXACT []
is_a: ECTO:9001745 ! exposure to antilipemic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35821 ! has exposure stimulus anticholesteremic drug
relationship: RO:0002309 CHEBI:35821 ! has exposure stimulus anticholesteremic drug

[Term]
id: ECTO:9001753
name: exposure to antirheumatic drug
def: "An exposure to antirheumatic drug." []
synonym: "antirheumatic drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35842 ! has exposure stimulus antirheumatic drug
relationship: RO:0002309 CHEBI:35842 ! has exposure stimulus antirheumatic drug

[Term]
id: ECTO:9001754
name: exposure to lipoxygenase inhibitor
def: "An exposure to lipoxygenase inhibitor." []
synonym: "lipoxygenase inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35856 ! has exposure stimulus lipoxygenase inhibitor
relationship: RO:0002309 CHEBI:35856 ! has exposure stimulus lipoxygenase inhibitor

[Term]
id: ECTO:9001755
name: exposure to antimicrobial drug
def: "An exposure to antimicrobial drug." []
synonym: "antimicrobial drug exposure" EXACT []
is_a: ECTO:0000544 ! exposure to antimicrobial agent
is_a: ECTO:9001711 ! exposure to antiinfective agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36043 ! has exposure stimulus antimicrobial drug
relationship: RO:0002309 CHEBI:36043 ! has exposure stimulus antimicrobial drug

[Term]
id: ECTO:9001756
name: exposure to antiviral drug
def: "An exposure to antiviral drug." []
synonym: "antiviral drug exposure" EXACT []
is_a: ECTO:9001648 ! exposure to antiviral agent
is_a: ECTO:9001755 ! exposure to antimicrobial drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36044 ! has exposure stimulus antiviral drug
relationship: RO:0002309 CHEBI:36044 ! has exposure stimulus antiviral drug

[Term]
id: ECTO:9001757
name: exposure to antibacterial drug
def: "An exposure to antibacterial drug." []
synonym: "antibacterial drug exposure" EXACT []
is_a: ECTO:9001694 ! exposure to antibacterial agent
is_a: ECTO:9001755 ! exposure to antimicrobial drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36047 ! has exposure stimulus antibacterial drug
relationship: RO:0002309 CHEBI:36047 ! has exposure stimulus antibacterial drug

[Term]
id: ECTO:9001758
name: exposure to oxytocic
def: "An exposure to oxytocic." []
synonym: "oxytocic exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36063 ! has exposure stimulus oxytocic
relationship: RO:0002309 CHEBI:36063 ! has exposure stimulus oxytocic

[Term]
id: ECTO:9001759
name: exposure to local anaesthetic
def: "An exposure to local anaesthetic." []
synonym: "local anaesthetic exposure" EXACT []
is_a: ECTO:9001793 ! exposure to anaesthetic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36333 ! has exposure stimulus local anaesthetic
relationship: RO:0002309 CHEBI:36333 ! has exposure stimulus local anaesthetic

[Term]
id: ECTO:9001760
name: exposure to trypanocidal drug
def: "An exposure to trypanocidal drug." []
synonym: "trypanocidal drug exposure" EXACT []
is_a: ECTO:9001751 ! exposure to antiprotozoal drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36335 ! has exposure stimulus trypanocidal drug
relationship: RO:0002309 CHEBI:36335 ! has exposure stimulus trypanocidal drug

[Term]
id: ECTO:9001761
name: exposure to EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
def: "An exposure to EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor." []
synonym: "EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37153 ! has exposure stimulus EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor
relationship: RO:0002309 CHEBI:37153 ! has exposure stimulus EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor

[Term]
id: ECTO:9001762
name: exposure to MRI contrast agent
def: "An exposure to MRI contrast agent." []
synonym: "MRI contrast agent exposure" EXACT []
is_a: ECTO:9001700 ! exposure to diagnostic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37335 ! has exposure stimulus MRI contrast agent
relationship: RO:0002309 CHEBI:37335 ! has exposure stimulus MRI contrast agent

[Term]
id: ECTO:9001763
name: exposure to protein kinase inhibitor
def: "An exposure to protein kinase inhibitor." []
synonym: "protein kinase inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37699 ! has exposure stimulus protein kinase inhibitor
relationship: RO:0002309 CHEBI:37699 ! has exposure stimulus protein kinase inhibitor

[Term]
id: ECTO:9001764
name: exposure to EC 2.7.11.13 (protein kinase C) inhibitor
def: "An exposure to EC 2.7.11.13 (protein kinase C) inhibitor." []
synonym: "EC 2.7.11.13 (protein kinase C) inhibitor exposure" EXACT []
is_a: ECTO:9001763 ! exposure to protein kinase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37700 ! has exposure stimulus EC 2.7.11.13 (protein kinase C) inhibitor
relationship: RO:0002309 CHEBI:37700 ! has exposure stimulus EC 2.7.11.13 (protein kinase C) inhibitor

[Term]
id: ECTO:9001765
name: exposure to EC 3.1.1.8 (cholinesterase) inhibitor
def: "An exposure to EC 3.1.1.8 (cholinesterase) inhibitor." []
synonym: "EC 3.1.1.8 (cholinesterase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37733 ! has exposure stimulus EC 3.1.1.8 (cholinesterase) inhibitor
relationship: RO:0002309 CHEBI:37733 ! has exposure stimulus EC 3.1.1.8 (cholinesterase) inhibitor

[Term]
id: ECTO:9001766
name: exposure to plant hormone
def: "An exposure to plant hormone." []
synonym: "plant hormone exposure" EXACT []
is_a: ECTO:0000516 ! exposure to hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37848 ! has exposure stimulus plant hormone
relationship: RO:0002309 CHEBI:37848 ! has exposure stimulus plant hormone

[Term]
id: ECTO:9001767
name: exposure to adrenergic antagonist
def: "An exposure to adrenergic antagonist." []
synonym: "adrenergic antagonist exposure" EXACT []
is_a: ECTO:9001773 ! exposure to adrenergic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37887 ! has exposure stimulus adrenergic antagonist
relationship: RO:0002309 CHEBI:37887 ! has exposure stimulus adrenergic antagonist

[Term]
id: ECTO:9001768
name: exposure to alpha-adrenergic antagonist
def: "An exposure to alpha-adrenergic antagonist." []
synonym: "alpha-adrenergic antagonist exposure" EXACT []
is_a: ECTO:9001767 ! exposure to adrenergic antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37890 ! has exposure stimulus alpha-adrenergic antagonist
relationship: RO:0002309 CHEBI:37890 ! has exposure stimulus alpha-adrenergic antagonist

[Term]
id: ECTO:9001769
name: exposure to phenothiazine antipsychotic drug
def: "An exposure to phenothiazine antipsychotic drug." []
synonym: "phenothiazine antipsychotic drug exposure" EXACT []
is_a: ECTO:9001972 ! exposure to first generation antipsychotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37930 ! has exposure stimulus phenothiazine antipsychotic drug
relationship: RO:0002309 CHEBI:37930 ! has exposure stimulus phenothiazine antipsychotic drug

[Term]
id: ECTO:9001770
name: exposure to H1-receptor antagonist
def: "An exposure to H1-receptor antagonist." []
synonym: "H1-receptor antagonist exposure" EXACT []
is_a: ECTO:9001771 ! exposure to histamine antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37955 ! has exposure stimulus H1-receptor antagonist
relationship: RO:0002309 CHEBI:37955 ! has exposure stimulus H1-receptor antagonist

[Term]
id: ECTO:9001771
name: exposure to histamine antagonist
def: "An exposure to histamine antagonist." []
synonym: "histamine antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37956 ! has exposure stimulus histamine antagonist
relationship: RO:0002309 CHEBI:37956 ! has exposure stimulus histamine antagonist

[Term]
id: ECTO:9001772
name: obsolete exposure to dye
is_obsolete: true
replaced_by: ECTO:0500005

[Term]
id: ECTO:9001773
name: exposure to adrenergic agent
def: "An exposure to adrenergic agent." []
synonym: "adrenergic agent exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37962 ! has exposure stimulus adrenergic agent
relationship: RO:0002309 CHEBI:37962 ! has exposure stimulus adrenergic agent

[Term]
id: ECTO:9001774
name: exposure to triazine insecticide
def: "An exposure to triazine insecticide." []
synonym: "triazine insecticide exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38060 ! has exposure stimulus triazine insecticide
relationship: RO:0002309 CHEBI:38060 ! has exposure stimulus triazine insecticide

[Term]
id: ECTO:9001775
name: exposure to antimalarial
def: "An exposure to antimalarial." []
synonym: "antimalarial exposure" EXACT []
is_a: ECTO:9001751 ! exposure to antiprotozoal drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38068 ! has exposure stimulus antimalarial
relationship: RO:0002309 CHEBI:38068 ! has exposure stimulus antimalarial

[Term]
id: ECTO:9001776
name: exposure to anti-arrhythmia drug
def: "An exposure to anti-arrhythmia drug." []
synonym: "anti-arrhythmia drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38070 ! has exposure stimulus anti-arrhythmia drug
relationship: RO:0002309 CHEBI:38070 ! has exposure stimulus anti-arrhythmia drug

[Term]
id: ECTO:9001777
name: exposure to cardiotonic drug
def: "An exposure to cardiotonic drug." []
synonym: "cardiotonic drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38147 ! has exposure stimulus cardiotonic drug
relationship: RO:0002309 CHEBI:38147 ! has exposure stimulus cardiotonic drug

[Term]
id: ECTO:9001778
name: exposure to phytosiderophore
def: "An exposure to phytosiderophore." []
synonym: "phytosiderophore exposure" EXACT []
is_a: ECTO:9001662 ! exposure to iron(3+) chelator
is_a: ECTO:9001669 ! exposure to ionophore
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38155 ! has exposure stimulus phytosiderophore
relationship: RO:0002309 CHEBI:38155 ! has exposure stimulus phytosiderophore

[Term]
id: ECTO:9001779
name: exposure to iron chelator
def: "An exposure to iron chelator." []
synonym: "iron chelator exposure" EXACT []
is_a: ECTO:9001780 ! exposure to chelator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38157 ! has exposure stimulus iron chelator
relationship: RO:0002309 CHEBI:38157 ! has exposure stimulus iron chelator

[Term]
id: ECTO:9001780
name: exposure to chelator
def: "An exposure to chelator." []
synonym: "chelator exposure" EXACT []
is_a: ECTO:0000738 ! exposure to ligand
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38161 ! has exposure stimulus chelator
relationship: RO:0002309 CHEBI:38161 ! has exposure stimulus chelator

[Term]
id: ECTO:9001781
name: exposure to calcium channel blocker
def: "An exposure to calcium channel blocker." []
synonym: "calcium channel blocker exposure" EXACT []
is_a: ECTO:9001791 ! exposure to calcium channel modulator
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38215 ! has exposure stimulus calcium channel blocker
relationship: RO:0002309 CHEBI:38215 ! has exposure stimulus calcium channel blocker

[Term]
id: ECTO:9001782
name: exposure to phytotoxin
def: "An exposure to phytotoxin." []
synonym: "phytotoxin exposure" EXACT []
is_a: ECTO:0000537 ! exposure to toxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38231 ! has exposure stimulus phytotoxin
relationship: RO:0002309 CHEBI:38231 ! has exposure stimulus phytotoxin

[Term]
id: ECTO:9001783
name: exposure to muscarinic agonist
def: "An exposure to muscarinic agonist." []
synonym: "muscarinic agonist exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38325 ! has exposure stimulus muscarinic agonist
relationship: RO:0002309 CHEBI:38325 ! has exposure stimulus muscarinic agonist

[Term]
id: ECTO:9001784
name: exposure to EC 3.1.1.7 (acetylcholinesterase) inhibitor
def: "An exposure to EC 3.1.1.7 (acetylcholinesterase) inhibitor." []
synonym: "EC 3.1.1.7 (acetylcholinesterase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38462 ! has exposure stimulus EC 3.1.1.7 (acetylcholinesterase) inhibitor
relationship: RO:0002309 CHEBI:38462 ! has exposure stimulus EC 3.1.1.7 (acetylcholinesterase) inhibitor

[Term]
id: ECTO:9001785
name: exposure to mitochondrial NADH:ubiquinone reductase inhibitor
def: "An exposure to mitochondrial NADH:ubiquinone reductase inhibitor." []
synonym: "mitochondrial NADH:ubiquinone reductase inhibitor exposure" EXACT []
is_a: ECTO:0000522 ! exposure to mitochondrial respiratory-chain inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38498 ! has exposure stimulus mitochondrial NADH:ubiquinone reductase inhibitor
relationship: RO:0002309 CHEBI:38498 ! has exposure stimulus mitochondrial NADH:ubiquinone reductase inhibitor

[Term]
id: ECTO:9001787
name: exposure to sodium channel blocker
def: "An exposure to sodium channel blocker." []
synonym: "sodium channel blocker exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38633 ! has exposure stimulus sodium channel blocker
relationship: RO:0002309 CHEBI:38633 ! has exposure stimulus sodium channel blocker

[Term]
id: ECTO:9001788
name: exposure to tyrosine kinase inhibitor
def: "An exposure to tyrosine kinase inhibitor." []
synonym: "tyrosine kinase inhibitor exposure" EXACT []
is_a: ECTO:9001763 ! exposure to protein kinase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38637 ! has exposure stimulus tyrosine kinase inhibitor
relationship: RO:0002309 CHEBI:38637 ! has exposure stimulus tyrosine kinase inhibitor

[Term]
id: ECTO:9001789
name: exposure to pediculicide
def: "An exposure to pediculicide." []
synonym: "pediculicide exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38706 ! has exposure stimulus pediculicide
relationship: RO:0002309 CHEBI:38706 ! has exposure stimulus pediculicide

[Term]
id: ECTO:9001790
name: exposure to calcium channel agonist
def: "An exposure to calcium channel agonist." []
synonym: "calcium channel agonist exposure" EXACT []
is_a: ECTO:9001791 ! exposure to calcium channel modulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38807 ! has exposure stimulus calcium channel agonist
relationship: RO:0002309 CHEBI:38807 ! has exposure stimulus calcium channel agonist

[Term]
id: ECTO:9001791
name: exposure to calcium channel modulator
def: "An exposure to calcium channel modulator." []
synonym: "calcium channel modulator exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38808 ! has exposure stimulus calcium channel modulator
relationship: RO:0002309 CHEBI:38808 ! has exposure stimulus calcium channel modulator

[Term]
id: ECTO:9001792
name: exposure to ryanodine receptor modulator
def: "An exposure to ryanodine receptor modulator." []
synonym: "ryanodine receptor modulator exposure" EXACT []
is_a: ECTO:9001791 ! exposure to calcium channel modulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38809 ! has exposure stimulus ryanodine receptor modulator
relationship: RO:0002309 CHEBI:38809 ! has exposure stimulus ryanodine receptor modulator

[Term]
id: ECTO:9001793
name: exposure to anaesthetic
def: "An exposure to anaesthetic." []
synonym: "anaesthetic exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38867 ! has exposure stimulus anaesthetic
relationship: RO:0002309 CHEBI:38867 ! has exposure stimulus anaesthetic

[Term]
id: ECTO:9001794
name: exposure to general anaesthetic
def: "An exposure to general anaesthetic." []
synonym: "general anaesthetic exposure" EXACT []
is_a: ECTO:9001793 ! exposure to anaesthetic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38869 ! has exposure stimulus general anaesthetic
relationship: RO:0002309 CHEBI:38869 ! has exposure stimulus general anaesthetic

[Term]
id: ECTO:9001795
name: exposure to inhalation anaesthetic
def: "An exposure to inhalation anaesthetic." []
synonym: "inhalation anaesthetic exposure" EXACT []
is_a: ECTO:9001794 ! exposure to general anaesthetic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38870 ! has exposure stimulus inhalation anaesthetic
relationship: RO:0002309 CHEBI:38870 ! has exposure stimulus inhalation anaesthetic

[Term]
id: ECTO:9001796
name: exposure to intravenous anaesthetic
def: "An exposure to intravenous anaesthetic." []
synonym: "intravenous anaesthetic exposure" EXACT []
is_a: ECTO:9001794 ! exposure to general anaesthetic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38877 ! has exposure stimulus intravenous anaesthetic
relationship: RO:0002309 CHEBI:38877 ! has exposure stimulus intravenous anaesthetic

[Term]
id: ECTO:9001797
name: exposure to schistosomicide drug
def: "An exposure to schistosomicide drug." []
synonym: "schistosomicide drug exposure" EXACT []
is_a: ECTO:9001713 ! exposure to anthelminthic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38941 ! has exposure stimulus schistosomicide drug
relationship: RO:0002309 CHEBI:38941 ! has exposure stimulus schistosomicide drug

[Term]
id: ECTO:9001798
name: exposure to GABA-gated chloride channel antagonist
def: "An exposure to GABA-gated chloride channel antagonist." []
synonym: "GABA-gated chloride channel antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38999 ! has exposure stimulus GABA-gated chloride channel antagonist
relationship: RO:0002309 CHEBI:38999 ! has exposure stimulus GABA-gated chloride channel antagonist

[Term]
id: ECTO:9001800
name: exposure to bridged diphenyl acaricide
def: "An exposure to bridged diphenyl acaricide." []
synonym: "bridged diphenyl acaricide exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39412 ! has exposure stimulus bridged diphenyl acaricide
relationship: RO:0002309 CHEBI:39412 ! has exposure stimulus bridged diphenyl acaricide

[Term]
id: ECTO:9001802
name: exposure to photosensitizing agent
def: "An exposure to photosensitizing agent." []
synonym: "photosensitizing agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47868 ! has exposure stimulus photosensitizing agent
relationship: RO:0002309 CHEBI:47868 ! has exposure stimulus photosensitizing agent

[Term]
id: ECTO:9001803
name: exposure to nicotinic acetylcholine receptor agonist
def: "An exposure to nicotinic acetylcholine receptor agonist." []
synonym: "nicotinic acetylcholine receptor agonist exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47958 ! has exposure stimulus nicotinic acetylcholine receptor agonist
relationship: RO:0002309 CHEBI:47958 ! has exposure stimulus nicotinic acetylcholine receptor agonist

[Term]
id: ECTO:9001804
name: exposure to protein synthesis inhibitor
def: "An exposure to protein synthesis inhibitor." []
synonym: "protein synthesis inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48001 ! has exposure stimulus protein synthesis inhibitor
relationship: RO:0002309 CHEBI:48001 ! has exposure stimulus protein synthesis inhibitor

[Term]
id: ECTO:9001805
name: exposure to antiseptic drug
def: "An exposure to antiseptic drug." []
synonym: "antiseptic drug exposure" EXACT []
is_a: ECTO:9001711 ! exposure to antiinfective agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48218 ! has exposure stimulus antiseptic drug
relationship: RO:0002309 CHEBI:48218 ! has exposure stimulus antiseptic drug

[Term]
id: ECTO:9001807
name: exposure to serotonergic antagonist
def: "An exposure to serotonergic antagonist." []
synonym: "serotonergic antagonist exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48279 ! has exposure stimulus serotonergic antagonist
relationship: RO:0002309 CHEBI:48279 ! has exposure stimulus serotonergic antagonist

[Term]
id: ECTO:9001808
name: exposure to fragrance
def: "An exposure to fragrance." []
synonym: "fragrance exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48318 ! has exposure stimulus fragrance
relationship: RO:0002309 CHEBI:48318 ! has exposure stimulus fragrance

[Term]
id: ECTO:9001809
name: exposure to polar solvent
def: "An exposure to polar solvent." []
synonym: "polar solvent exposure" EXACT []
is_a: ECTO:9000107 ! exposure to solvent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48354 ! has exposure stimulus polar solvent
relationship: RO:0002309 CHEBI:48354 ! has exposure stimulus polar solvent

[Term]
id: ECTO:9001810
name: exposure to non-polar solvent
def: "An exposure to non-polar solvent." []
synonym: "non-polar solvent exposure" EXACT []
is_a: ECTO:9000107 ! exposure to solvent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48355 ! has exposure stimulus non-polar solvent
relationship: RO:0002309 CHEBI:48355 ! has exposure stimulus non-polar solvent

[Term]
id: ECTO:9001811
name: exposure to protic solvent
def: "An exposure to protic solvent." []
synonym: "protic solvent exposure" EXACT []
is_a: ECTO:0000650 ! exposure to Bronsted acid
is_a: ECTO:9001809 ! exposure to polar solvent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48356 ! has exposure stimulus protic solvent
relationship: RO:0002309 CHEBI:48356 ! has exposure stimulus protic solvent

[Term]
id: ECTO:9001812
name: exposure to polar aprotic solvent
def: "An exposure to polar aprotic solvent." []
synonym: "polar aprotic solvent exposure" EXACT []
is_a: ECTO:9001809 ! exposure to polar solvent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48358 ! has exposure stimulus polar aprotic solvent
relationship: RO:0002309 CHEBI:48358 ! has exposure stimulus polar aprotic solvent

[Term]
id: ECTO:9001813
name: exposure to amphiprotic solvent
def: "An exposure to amphiprotic solvent." []
synonym: "amphiprotic solvent exposure" EXACT []
is_a: ECTO:9001811 ! exposure to protic solvent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48360 ! has exposure stimulus amphiprotic solvent
relationship: RO:0002309 CHEBI:48360 ! has exposure stimulus amphiprotic solvent

[Term]
id: ECTO:9001814
name: exposure to antiparkinson drug
def: "An exposure to antiparkinson drug." []
synonym: "antiparkinson drug exposure" EXACT []
is_a: ECTO:9001977 ! exposure to antidyskinesia agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48407 ! has exposure stimulus antiparkinson drug
relationship: RO:0002309 CHEBI:48407 ! has exposure stimulus antiparkinson drug

[Term]
id: ECTO:9001815
name: exposure to angiogenesis inhibitor
def: "An exposure to angiogenesis inhibitor." []
synonym: "angiogenesis inhibitor exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48422 ! has exposure stimulus angiogenesis inhibitor
relationship: RO:0002309 CHEBI:48422 ! has exposure stimulus angiogenesis inhibitor

[Term]
id: ECTO:9001816
name: exposure to EC 1.1.1.21 (aldehyde reductase) inhibitor
def: "An exposure to EC 1.1.1.21 (aldehyde reductase) inhibitor." []
synonym: "EC 1.1.1.21 (aldehyde reductase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48550 ! has exposure stimulus EC 1.1.1.21 (aldehyde reductase) inhibitor
relationship: RO:0002309 CHEBI:48550 ! has exposure stimulus EC 1.1.1.21 (aldehyde reductase) inhibitor

[Term]
id: ECTO:9001817
name: exposure to dopaminergic agent
def: "An exposure to dopaminergic agent." []
synonym: "dopaminergic agent exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48560 ! has exposure stimulus dopaminergic agent
relationship: RO:0002309 CHEBI:48560 ! has exposure stimulus dopaminergic agent

[Term]
id: ECTO:9001818
name: exposure to dopaminergic antagonist
def: "An exposure to dopaminergic antagonist." []
synonym: "dopaminergic antagonist exposure" EXACT []
is_a: ECTO:9001817 ! exposure to dopaminergic agent
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48561 ! has exposure stimulus dopaminergic antagonist
relationship: RO:0002309 CHEBI:48561 ! has exposure stimulus dopaminergic antagonist

[Term]
id: ECTO:9001819
name: exposure to radical scavenger
def: "An exposure to radical scavenger." []
synonym: "radical scavenger exposure" EXACT []
is_a: ECTO:9001647 ! exposure to antioxidant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48578 ! has exposure stimulus radical scavenger
relationship: RO:0002309 CHEBI:48578 ! has exposure stimulus radical scavenger

[Term]
id: ECTO:9001820
name: exposure to fibrin modulating drug
def: "An exposure to fibrin modulating drug." []
synonym: "fibrin modulating drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48676 ! has exposure stimulus fibrin modulating drug
relationship: RO:0002309 CHEBI:48676 ! has exposure stimulus fibrin modulating drug

[Term]
id: ECTO:9001822
name: exposure to antagonist
def: "An exposure to antagonist." []
synonym: "antagonist exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48706 ! has exposure stimulus antagonist
relationship: RO:0002309 CHEBI:48706 ! has exposure stimulus antagonist

[Term]
id: ECTO:9001823
name: exposure to cholinergic antagonist
def: "An exposure to cholinergic antagonist." []
synonym: "cholinergic antagonist exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48873 ! has exposure stimulus cholinergic antagonist
relationship: RO:0002309 CHEBI:48873 ! has exposure stimulus cholinergic antagonist

[Term]
id: ECTO:9001824
name: exposure to muscarinic antagonist
def: "An exposure to muscarinic antagonist." []
synonym: "muscarinic antagonist exposure" EXACT []
is_a: ECTO:9001823 ! exposure to cholinergic antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48876 ! has exposure stimulus muscarinic antagonist
relationship: RO:0002309 CHEBI:48876 ! has exposure stimulus muscarinic antagonist

[Term]
id: ECTO:9001825
name: exposure to nicotinic antagonist
def: "An exposure to nicotinic antagonist." []
synonym: "nicotinic antagonist exposure" EXACT []
is_a: ECTO:9001823 ! exposure to cholinergic antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48878 ! has exposure stimulus nicotinic antagonist
relationship: RO:0002309 CHEBI:48878 ! has exposure stimulus nicotinic antagonist

[Term]
id: ECTO:9001826
name: exposure to prostaglandin antagonist
def: "An exposure to prostaglandin antagonist." []
synonym: "prostaglandin antagonist exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49023 ! has exposure stimulus prostaglandin antagonist
relationship: RO:0002309 CHEBI:49023 ! has exposure stimulus prostaglandin antagonist

[Term]
id: ECTO:9001827
name: exposure to drug metabolite
def: "An exposure to drug metabolite." []
synonym: "drug metabolite exposure" EXACT []
is_a: ECTO:9002027 ! exposure to xenobiotic metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49103 ! has exposure stimulus drug metabolite
relationship: RO:0002309 CHEBI:49103 ! has exposure stimulus drug metabolite

[Term]
id: ECTO:9001828
name: exposure to peripheral nervous system drug
def: "An exposure to peripheral nervous system drug." []
synonym: "peripheral nervous system drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49110 ! has exposure stimulus peripheral nervous system drug
relationship: RO:0002309 CHEBI:49110 ! has exposure stimulus peripheral nervous system drug

[Term]
id: ECTO:9001829
name: exposure to anti-asthmatic drug
def: "An exposure to anti-asthmatic drug." []
synonym: "anti-asthmatic drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49167 ! has exposure stimulus anti-asthmatic drug
relationship: RO:0002309 CHEBI:49167 ! has exposure stimulus anti-asthmatic drug

[Term]
id: ECTO:9001830
name: exposure to anti-ulcer drug
def: "An exposure to anti-ulcer drug." []
synonym: "anti-ulcer drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49201 ! has exposure stimulus anti-ulcer drug
relationship: RO:0002309 CHEBI:49201 ! has exposure stimulus anti-ulcer drug

[Term]
id: ECTO:9001831
name: exposure to contraceptive drug
def: "An exposure to contraceptive drug." []
synonym: "contraceptive drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49323 ! has exposure stimulus contraceptive drug
relationship: RO:0002309 CHEBI:49323 ! has exposure stimulus contraceptive drug

[Term]
id: ECTO:9001832
name: exposure to excitatory amino acid agonist
def: "An exposure to excitatory amino acid agonist." []
synonym: "excitatory amino acid agonist exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50103 ! has exposure stimulus excitatory amino acid agonist
relationship: RO:0002309 CHEBI:50103 ! has exposure stimulus excitatory amino acid agonist

[Term]
id: ECTO:9001833
name: exposure to androgen
def: "An exposure to androgen." []
synonym: "androgen exposure" EXACT []
is_a: ECTO:9002127 ! exposure to sex hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50113 ! has exposure stimulus androgen
relationship: RO:0002309 CHEBI:50113 ! has exposure stimulus androgen

[Term]
id: ECTO:9001834
name: obsolete estrogen exposure
is_obsolete: true
replaced_by: ECTO:9000010

[Term]
id: ECTO:9001835
name: exposure to bronchoconstrictor agent
def: "An exposure to bronchoconstrictor agent." []
synonym: "bronchoconstrictor agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50141 ! has exposure stimulus bronchoconstrictor agent
relationship: RO:0002309 CHEBI:50141 ! has exposure stimulus bronchoconstrictor agent

[Term]
id: ECTO:9001836
name: exposure to keratolytic drug
def: "An exposure to keratolytic drug." []
synonym: "keratolytic drug exposure" EXACT []
is_a: ECTO:9001837 ! exposure to dermatologic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50176 ! has exposure stimulus keratolytic drug
relationship: RO:0002309 CHEBI:50176 ! has exposure stimulus keratolytic drug

[Term]
id: ECTO:9001837
name: exposure to dermatologic drug
def: "An exposure to dermatologic drug." []
synonym: "dermatologic drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50177 ! has exposure stimulus dermatologic drug
relationship: RO:0002309 CHEBI:50177 ! has exposure stimulus dermatologic drug

[Term]
id: ECTO:9001839
name: exposure to EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
def: "An exposure to EC 3.1.4.* (phosphoric diester hydrolase) inhibitor." []
synonym: "EC 3.1.4.* (phosphoric diester hydrolase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50218 ! has exposure stimulus EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
relationship: RO:0002309 CHEBI:50218 ! has exposure stimulus EC 3.1.4.* (phosphoric diester hydrolase) inhibitor

[Term]
id: ECTO:9001840
name: exposure to antidote
def: "An exposure to antidote." []
synonym: "antidote exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50247 ! has exposure stimulus antidote
relationship: RO:0002309 CHEBI:50247 ! has exposure stimulus antidote

[Term]
id: ECTO:9001841
name: exposure to hematologic agent
def: "An exposure to hematologic agent." []
synonym: "hematologic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50248 ! has exposure stimulus hematologic agent
relationship: RO:0002309 CHEBI:50248 ! has exposure stimulus hematologic agent

[Term]
id: ECTO:9001842
name: exposure to anticoagulant
def: "An exposure to anticoagulant." []
synonym: "anticoagulant exposure" EXACT []
is_a: ECTO:9001841 ! exposure to hematologic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50249 ! has exposure stimulus anticoagulant
relationship: RO:0002309 CHEBI:50249 ! has exposure stimulus anticoagulant

[Term]
id: ECTO:9001843
name: exposure to prodrug
def: "An exposure to prodrug." []
synonym: "prodrug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50266 ! has exposure stimulus prodrug
relationship: RO:0002309 CHEBI:50266 ! has exposure stimulus prodrug

[Term]
id: ECTO:9001844
name: exposure to GABA modulator
def: "An exposure to GABA modulator." []
synonym: "GABA modulator exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50268 ! has exposure stimulus GABA modulator
relationship: RO:0002309 CHEBI:50268 ! has exposure stimulus GABA modulator

[Term]
id: ECTO:9001845
name: exposure to EC 5.99.1.2 (DNA topoisomerase) inhibitor
def: "An exposure to EC 5.99.1.2 (DNA topoisomerase) inhibitor." []
synonym: "EC 5.99.1.2 (DNA topoisomerase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50276 ! has exposure stimulus EC 5.99.1.2 (DNA topoisomerase) inhibitor
relationship: RO:0002309 CHEBI:50276 ! has exposure stimulus EC 5.99.1.2 (DNA topoisomerase) inhibitor

[Term]
id: ECTO:9001846
name: exposure to parasympatholytic
def: "An exposure to parasympatholytic." []
synonym: "parasympatholytic exposure" EXACT []
is_a: ECTO:9001823 ! exposure to cholinergic antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50370 ! has exposure stimulus parasympatholytic
relationship: RO:0002309 CHEBI:50370 ! has exposure stimulus parasympatholytic

[Term]
id: ECTO:9001847
name: exposure to EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
def: "An exposure to EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor." []
synonym: "EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50390 ! has exposure stimulus EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
relationship: RO:0002309 CHEBI:50390 ! has exposure stimulus EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor

[Term]
id: ECTO:9001849
name: exposure to platelet aggregation inhibitor
def: "An exposure to platelet aggregation inhibitor." []
synonym: "platelet aggregation inhibitor exposure" EXACT []
is_a: ECTO:9001841 ! exposure to hematologic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50427 ! has exposure stimulus platelet aggregation inhibitor
relationship: RO:0002309 CHEBI:50427 ! has exposure stimulus platelet aggregation inhibitor

[Term]
id: ECTO:9001850
name: exposure to EC 2.5.1.15 (dihydropteroate synthase) inhibitor
def: "An exposure to EC 2.5.1.15 (dihydropteroate synthase) inhibitor." []
synonym: "EC 2.5.1.15 (dihydropteroate synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50502 ! has exposure stimulus EC 2.5.1.15 (dihydropteroate synthase) inhibitor
relationship: RO:0002309 CHEBI:50502 ! has exposure stimulus EC 2.5.1.15 (dihydropteroate synthase) inhibitor

[Term]
id: ECTO:9001851
name: exposure to laxative
def: "An exposure to laxative." []
synonym: "laxative exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50503 ! has exposure stimulus laxative
relationship: RO:0002309 CHEBI:50503 ! has exposure stimulus laxative

[Term]
id: ECTO:9001852
name: exposure to sweetening agent
def: "An exposure to sweetening agent." []
synonym: "sweetening agent exposure" EXACT []
is_a: ECTO:9001738 ! exposure to flavouring agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50505 ! has exposure stimulus sweetening agent
relationship: RO:0002309 CHEBI:50505 ! has exposure stimulus sweetening agent

[Term]
id: ECTO:9001853
name: exposure to potassium channel blocker
def: "An exposure to potassium channel blocker." []
synonym: "potassium channel blocker exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50509 ! has exposure stimulus potassium channel blocker
relationship: RO:0002309 CHEBI:50509 ! has exposure stimulus potassium channel blocker

[Term]
id: ECTO:9001854
name: exposure to mydriatic agent
def: "An exposure to mydriatic agent." []
synonym: "mydriatic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50513 ! has exposure stimulus mydriatic agent
relationship: RO:0002309 CHEBI:50513 ! has exposure stimulus mydriatic agent

[Term]
id: ECTO:9001855
name: exposure to vasoconstrictor agent
def: "An exposure to vasoconstrictor agent." []
synonym: "vasoconstrictor agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50514 ! has exposure stimulus vasoconstrictor agent
relationship: RO:0002309 CHEBI:50514 ! has exposure stimulus vasoconstrictor agent

[Term]
id: ECTO:9001856
name: exposure to protein denaturant
def: "An exposure to protein denaturant." []
synonym: "protein denaturant exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50533 ! has exposure stimulus protein denaturant
relationship: RO:0002309 CHEBI:50533 ! has exposure stimulus protein denaturant

[Term]
id: ECTO:9001857
name: exposure to nitric oxide donor
def: "An exposure to nitric oxide donor." []
synonym: "nitric oxide donor exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50566 ! has exposure stimulus nitric oxide donor
relationship: RO:0002309 CHEBI:50566 ! has exposure stimulus nitric oxide donor

[Term]
id: ECTO:9001858
name: exposure to cyclooxygenase 2 inhibitor
def: "An exposure to cyclooxygenase 2 inhibitor." []
synonym: "cyclooxygenase 2 inhibitor exposure" EXACT []
is_a: ECTO:9001735 ! exposure to EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50629 ! has exposure stimulus cyclooxygenase 2 inhibitor
relationship: RO:0002309 CHEBI:50629 ! has exposure stimulus cyclooxygenase 2 inhibitor

[Term]
id: ECTO:9001859
name: exposure to cyclooxygenase 1 inhibitor
def: "An exposure to cyclooxygenase 1 inhibitor." []
synonym: "cyclooxygenase 1 inhibitor exposure" EXACT []
is_a: ECTO:9001735 ! exposure to EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50630 ! has exposure stimulus cyclooxygenase 1 inhibitor
relationship: RO:0002309 CHEBI:50630 ! has exposure stimulus cyclooxygenase 1 inhibitor

[Term]
id: ECTO:9001860
name: exposure to bone density conservation agent
def: "An exposure to bone density conservation agent." []
synonym: "bone density conservation agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50646 ! has exposure stimulus bone density conservation agent
relationship: RO:0002309 CHEBI:50646 ! has exposure stimulus bone density conservation agent

[Term]
id: ECTO:9001861
name: exposure to antithyroid drug
def: "An exposure to antithyroid drug." []
synonym: "antithyroid drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50671 ! has exposure stimulus antithyroid drug
relationship: RO:0002309 CHEBI:50671 ! has exposure stimulus antithyroid drug

[Term]
id: ECTO:9001862
name: exposure to EC 1.5.1.3 (dihydrofolate reductase) inhibitor
def: "An exposure to EC 1.5.1.3 (dihydrofolate reductase) inhibitor." []
synonym: "EC 1.5.1.3 (dihydrofolate reductase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
is_a: ECTO:9001705 ! exposure to antimetabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50683 ! has exposure stimulus EC 1.5.1.3 (dihydrofolate reductase) inhibitor
relationship: RO:0002309 CHEBI:50683 ! has exposure stimulus EC 1.5.1.3 (dihydrofolate reductase) inhibitor

[Term]
id: ECTO:9001863
name: exposure to cross-linking reagent
def: "An exposure to cross-linking reagent." []
synonym: "cross-linking reagent exposure" EXACT []
is_a: ECTO:9001701 ! exposure to reagent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50684 ! has exposure stimulus cross-linking reagent
relationship: RO:0002309 CHEBI:50684 ! has exposure stimulus cross-linking reagent

[Term]
id: ECTO:9001864
name: exposure to abortifacient
def: "An exposure to abortifacient." []
synonym: "abortifacient exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50691 ! has exposure stimulus abortifacient
relationship: RO:0002309 CHEBI:50691 ! has exposure stimulus abortifacient

[Term]
id: ECTO:9001865
name: exposure to nutraceutical
def: "An exposure to nutraceutical." []
synonym: "nutraceutical exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50733 ! has exposure stimulus nutraceutical
relationship: RO:0002309 CHEBI:50733 ! has exposure stimulus nutraceutical

[Term]
id: ECTO:9001866
name: exposure to antipsoriatic
def: "An exposure to antipsoriatic." []
synonym: "antipsoriatic exposure" EXACT []
is_a: ECTO:9001837 ! exposure to dermatologic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50748 ! has exposure stimulus antipsoriatic
relationship: RO:0002309 CHEBI:50748 ! has exposure stimulus antipsoriatic

[Term]
id: ECTO:9001867
name: exposure to EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
def: "An exposure to EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor." []
synonym: "EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50750 ! has exposure stimulus EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
relationship: RO:0002309 CHEBI:50750 ! has exposure stimulus EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor

[Term]
id: ECTO:9001868
name: exposure to appetite enhancer
def: "An exposure to appetite enhancer." []
synonym: "appetite enhancer exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50779 ! has exposure stimulus appetite enhancer
relationship: RO:0002309 CHEBI:50779 ! has exposure stimulus appetite enhancer

[Term]
id: ECTO:9001869
name: exposure to immunomodulator
def: "An exposure to immunomodulator." []
synonym: "immunomodulator exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50846 ! has exposure stimulus immunomodulator
relationship: RO:0002309 CHEBI:50846 ! has exposure stimulus immunomodulator

[Term]
id: ECTO:9001870
name: exposure to immunological adjuvant
def: "An exposure to immunological adjuvant." []
synonym: "immunological adjuvant exposure" EXACT []
is_a: ECTO:9001869 ! exposure to immunomodulator
is_a: ECTO:9001914 ! exposure to adjuvant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50847 ! has exposure stimulus immunological adjuvant
relationship: RO:0002309 CHEBI:50847 ! has exposure stimulus immunological adjuvant

[Term]
id: ECTO:9001871
name: exposure to antiatherogenic agent
def: "An exposure to antiatherogenic agent." []
synonym: "antiatherogenic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50855 ! has exposure stimulus antiatherogenic agent
relationship: RO:0002309 CHEBI:50855 ! has exposure stimulus antiatherogenic agent

[Term]
id: ECTO:9001872
name: exposure to anti-allergic agent
def: "An exposure to anti-allergic agent." []
synonym: "anti-allergic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50857 ! has exposure stimulus anti-allergic agent
relationship: RO:0002309 CHEBI:50857 ! has exposure stimulus anti-allergic agent

[Term]
id: ECTO:9001876
name: exposure to teratogenic agent
def: "An exposure to teratogenic agent." []
synonym: "teratogenic agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50905 ! has exposure stimulus teratogenic agent
relationship: RO:0002309 CHEBI:50905 ! has exposure stimulus teratogenic agent

[Term]
id: ECTO:9001877
name: exposure to hepatotoxic agent
def: "An exposure to hepatotoxic agent." []
synonym: "hepatotoxic agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50908 ! has exposure stimulus hepatotoxic agent
relationship: RO:0002309 CHEBI:50908 ! has exposure stimulus hepatotoxic agent

[Term]
id: ECTO:9001878
name: exposure to nephrotoxic agent
def: "An exposure to nephrotoxic agent." []
synonym: "nephrotoxic agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50909 ! has exposure stimulus nephrotoxic agent
relationship: RO:0002309 CHEBI:50909 ! has exposure stimulus nephrotoxic agent

[Term]
id: ECTO:9001880
name: exposure to EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
def: "An exposure to EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor." []
synonym: "EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50914 ! has exposure stimulus EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
relationship: RO:0002309 CHEBI:50914 ! has exposure stimulus EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor

[Term]
id: ECTO:9001881
name: exposure to antiemetic
def: "An exposure to antiemetic." []
synonym: "antiemetic exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50919 ! has exposure stimulus antiemetic
relationship: RO:0002309 CHEBI:50919 ! has exposure stimulus antiemetic

[Term]
id: ECTO:9001882
name: exposure to EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
def: "An exposure to EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor." []
synonym: "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor exposure" EXACT []
is_a: ECTO:9001763 ! exposure to protein kinase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50925 ! has exposure stimulus EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
relationship: RO:0002309 CHEBI:50925 ! has exposure stimulus EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor

[Term]
id: ECTO:9001883
name: exposure to serotonin uptake inhibitor
def: "An exposure to serotonin uptake inhibitor." []
synonym: "serotonin uptake inhibitor exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50949 ! has exposure stimulus serotonin uptake inhibitor
relationship: RO:0002309 CHEBI:50949 ! has exposure stimulus serotonin uptake inhibitor

[Term]
id: ECTO:9001884
name: exposure to dopamine uptake inhibitor
def: "An exposure to dopamine uptake inhibitor." []
synonym: "dopamine uptake inhibitor exposure" EXACT []
is_a: ECTO:9001817 ! exposure to dopaminergic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51039 ! has exposure stimulus dopamine uptake inhibitor
relationship: RO:0002309 CHEBI:51039 ! has exposure stimulus dopamine uptake inhibitor

[Term]
id: ECTO:9001885
name: exposure to antitussive
def: "An exposure to antitussive." []
synonym: "antitussive exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51177 ! has exposure stimulus antitussive
relationship: RO:0002309 CHEBI:51177 ! has exposure stimulus antitussive

[Term]
id: ECTO:9001886
name: exposure to muscle relaxant
def: "An exposure to muscle relaxant." []
synonym: "muscle relaxant exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51371 ! has exposure stimulus muscle relaxant
relationship: RO:0002309 CHEBI:51371 ! has exposure stimulus muscle relaxant

[Term]
id: ECTO:9001888
name: exposure to mitogen
def: "An exposure to mitogen." []
synonym: "mitogen exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52290 ! has exposure stimulus mitogen
relationship: RO:0002309 CHEBI:52290 ! has exposure stimulus mitogen

[Term]
id: ECTO:9001889
name: exposure to EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
def: "An exposure to EC 3.2.1.18 (exo-alpha-sialidase) inhibitor." []
synonym: "EC 3.2.1.18 (exo-alpha-sialidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
is_a: ECTO:9001756 ! exposure to antiviral drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52425 ! has exposure stimulus EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
relationship: RO:0002309 CHEBI:52425 ! has exposure stimulus EC 3.2.1.18 (exo-alpha-sialidase) inhibitor

[Term]
id: ECTO:9001890
name: exposure to proteasome inhibitor
def: "An exposure to proteasome inhibitor." []
synonym: "proteasome inhibitor exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52726 ! has exposure stimulus proteasome inhibitor
relationship: RO:0002309 CHEBI:52726 ! has exposure stimulus proteasome inhibitor

[Term]
id: ECTO:9001891
name: exposure to epitope
def: "An exposure to epitope." []
synonym: "epitope exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53000 ! has exposure stimulus epitope
relationship: RO:0002309 CHEBI:53000 ! has exposure stimulus epitope

[Term]
id: ECTO:9001892
name: exposure to adenosine A2A receptor antagonist
def: "An exposure to adenosine A2A receptor antagonist." []
synonym: "adenosine A2A receptor antagonist exposure" EXACT []
is_a: ECTO:9002006 ! exposure to adenosine receptor antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53121 ! has exposure stimulus adenosine A2A receptor antagonist
relationship: RO:0002309 CHEBI:53121 ! has exposure stimulus adenosine A2A receptor antagonist

[Term]
id: ECTO:9001893
name: exposure to GHB receptor agonist
def: "An exposure to GHB receptor agonist." []
synonym: "GHB receptor agonist exposure" EXACT []
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53353 ! has exposure stimulus GHB receptor agonist
relationship: RO:0002309 CHEBI:53353 ! has exposure stimulus GHB receptor agonist

[Term]
id: ECTO:9001894
name: exposure to EC 1.1.1.205 (IMP dehydrogenase) inhibitor
def: "An exposure to EC 1.1.1.205 (IMP dehydrogenase) inhibitor." []
synonym: "EC 1.1.1.205 (IMP dehydrogenase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53746 ! has exposure stimulus EC 1.1.1.205 (IMP dehydrogenase) inhibitor
relationship: RO:0002309 CHEBI:53746 ! has exposure stimulus EC 1.1.1.205 (IMP dehydrogenase) inhibitor

[Term]
id: ECTO:9001895
name: exposure to antispasmodic drug
def: "An exposure to antispasmodic drug." []
synonym: "antispasmodic drug exposure" EXACT []
is_a: ECTO:9001886 ! exposure to muscle relaxant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53784 ! has exposure stimulus antispasmodic drug
relationship: RO:0002309 CHEBI:53784 ! has exposure stimulus antispasmodic drug

[Term]
id: ECTO:9001896
name: exposure to mu-opioid receptor agonist
def: "An exposure to mu-opioid receptor agonist." []
synonym: "mu-opioid receptor agonist exposure" EXACT []
is_a: ECTO:9001911 ! exposure to opioid receptor agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:55322 ! has exposure stimulus mu-opioid receptor agonist
relationship: RO:0002309 CHEBI:55322 ! has exposure stimulus mu-opioid receptor agonist

[Term]
id: ECTO:9001897
name: exposure to antidiarrhoeal drug
def: "An exposure to antidiarrhoeal drug." []
synonym: "antidiarrhoeal drug exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:55323 ! has exposure stimulus antidiarrhoeal drug
relationship: RO:0002309 CHEBI:55323 ! has exposure stimulus antidiarrhoeal drug

[Term]
id: ECTO:9001898
name: exposure to antigen
def: "An exposure to antigen." []
synonym: "antigen exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59132 ! has exposure stimulus antigen
relationship: RO:0002309 CHEBI:59132 ! has exposure stimulus antigen

[Term]
id: ECTO:9001900
name: exposure to hapten
def: "An exposure to hapten." []
synonym: "hapten exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59174 ! has exposure stimulus hapten
relationship: RO:0002309 CHEBI:59174 ! has exposure stimulus hapten

[Term]
id: ECTO:9001901
name: exposure to DNA synthesis inhibitor
def: "An exposure to DNA synthesis inhibitor." []
synonym: "DNA synthesis inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59517 ! has exposure stimulus DNA synthesis inhibitor
relationship: RO:0002309 CHEBI:59517 ! has exposure stimulus DNA synthesis inhibitor

[Term]
id: ECTO:9001902
name: exposure to phosphoantigen
def: "An exposure to phosphoantigen." []
synonym: "phosphoantigen exposure" EXACT []
is_a: ECTO:9001898 ! exposure to antigen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59544 ! has exposure stimulus phosphoantigen
relationship: RO:0002309 CHEBI:59544 ! has exposure stimulus phosphoantigen

[Term]
id: ECTO:9001903
name: exposure to antipruritic drug
def: "An exposure to antipruritic drug." []
synonym: "antipruritic drug exposure" EXACT []
is_a: ECTO:9001837 ! exposure to dermatologic drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59683 ! has exposure stimulus antipruritic drug
relationship: RO:0002309 CHEBI:59683 ! has exposure stimulus antipruritic drug

[Term]
id: ECTO:9001904
name: exposure to electrophilic reagent
def: "An exposure to electrophilic reagent." []
synonym: "electrophilic reagent exposure" EXACT []
is_a: ECTO:9001701 ! exposure to reagent
is_a: ECTO:9002146 ! exposure to acids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59739 ! has exposure stimulus electrophilic reagent
relationship: RO:0002309 CHEBI:59739 ! has exposure stimulus electrophilic reagent

[Term]
id: ECTO:9001905
name: exposure to nucleophilic reagent
def: "An exposure to nucleophilic reagent." []
synonym: "nucleophilic reagent exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
is_a: ECTO:9001701 ! exposure to reagent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59740 ! has exposure stimulus nucleophilic reagent
relationship: RO:0002309 CHEBI:59740 ! has exposure stimulus nucleophilic reagent

[Term]
id: ECTO:9001906
name: exposure to progestin
def: "An exposure to progestin." []
synonym: "progestin exposure" EXACT []
is_a: ECTO:9002127 ! exposure to sex hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59826 ! has exposure stimulus progestin
relationship: RO:0002309 CHEBI:59826 ! has exposure stimulus progestin

[Term]
id: ECTO:9001907
name: exposure to EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
def: "An exposure to EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor." []
synonym: "EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
is_a: ECTO:9001648 ! exposure to antiviral agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59897 ! has exposure stimulus EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
relationship: RO:0002309 CHEBI:59897 ! has exposure stimulus EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor

[Term]
id: ECTO:9001908
name: exposure to EC 1.14.18.1 (tyrosinase) inhibitor
def: "An exposure to EC 1.14.18.1 (tyrosinase) inhibitor." []
synonym: "EC 1.14.18.1 (tyrosinase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59997 ! has exposure stimulus EC 1.14.18.1 (tyrosinase) inhibitor
relationship: RO:0002309 CHEBI:59997 ! has exposure stimulus EC 1.14.18.1 (tyrosinase) inhibitor

[Term]
id: ECTO:9001909
name: exposure to EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
def: "An exposure to EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor." []
synonym: "EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60186 ! has exposure stimulus EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
relationship: RO:0002309 CHEBI:60186 ! has exposure stimulus EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor

[Term]
id: ECTO:9001910
name: exposure to thyroid hormone
def: "An exposure to thyroid hormone." []
synonym: "thyroid hormone exposure" EXACT []
is_a: ECTO:0000516 ! exposure to hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60311 ! has exposure stimulus thyroid hormone
relationship: RO:0002309 CHEBI:60311 ! has exposure stimulus thyroid hormone

[Term]
id: ECTO:9001911
name: exposure to opioid receptor agonist
def: "An exposure to opioid receptor agonist." []
synonym: "opioid receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60606 ! has exposure stimulus opioid receptor agonist
relationship: RO:0002309 CHEBI:60606 ! has exposure stimulus opioid receptor agonist

[Term]
id: ECTO:9001912
name: exposure to NMDA receptor antagonist
def: "An exposure to NMDA receptor antagonist." []
synonym: "NMDA receptor antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60643 ! has exposure stimulus NMDA receptor antagonist
relationship: RO:0002309 CHEBI:60643 ! has exposure stimulus NMDA receptor antagonist

[Term]
id: ECTO:9001913
name: exposure to anaesthesia adjuvant
def: "An exposure to anaesthesia adjuvant." []
synonym: "anaesthesia adjuvant exposure" EXACT []
is_a: ECTO:9001914 ! exposure to adjuvant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60807 ! has exposure stimulus anaesthesia adjuvant
relationship: RO:0002309 CHEBI:60807 ! has exposure stimulus anaesthesia adjuvant

[Term]
id: ECTO:9001914
name: exposure to adjuvant
def: "An exposure to adjuvant." []
synonym: "adjuvant exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60809 ! has exposure stimulus adjuvant
relationship: RO:0002309 CHEBI:60809 ! has exposure stimulus adjuvant

[Term]
id: ECTO:9001915
name: exposure to tubulin modulator
def: "An exposure to tubulin modulator." []
synonym: "tubulin modulator exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60832 ! has exposure stimulus tubulin modulator
relationship: RO:0002309 CHEBI:60832 ! has exposure stimulus tubulin modulator

[Term]
id: ECTO:9001916
name: exposure to nephrotoxin
def: "An exposure to nephrotoxin." []
synonym: "nephrotoxin exposure" EXACT []
is_a: ECTO:0000537 ! exposure to toxin
is_a: ECTO:9001878 ! exposure to nephrotoxic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61015 ! has exposure stimulus nephrotoxin
relationship: RO:0002309 CHEBI:61015 ! has exposure stimulus nephrotoxin

[Term]
id: ECTO:9001917
name: exposure to angiotensin receptor antagonist
def: "An exposure to angiotensin receptor antagonist." []
synonym: "angiotensin receptor antagonist exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61016 ! has exposure stimulus angiotensin receptor antagonist
relationship: RO:0002309 CHEBI:61016 ! has exposure stimulus angiotensin receptor antagonist

[Term]
id: ECTO:9001918
name: exposure to EC 3.5.1.98 (histone deacetylase) inhibitor
def: "An exposure to EC 3.5.1.98 (histone deacetylase) inhibitor." []
synonym: "EC 3.5.1.98 (histone deacetylase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61115 ! has exposure stimulus EC 3.5.1.98 (histone deacetylase) inhibitor
relationship: RO:0002309 CHEBI:61115 ! has exposure stimulus EC 3.5.1.98 (histone deacetylase) inhibitor

[Term]
id: ECTO:9001919
name: exposure to EC 1.14.13.39 (nitric oxide synthase) inhibitor
def: "An exposure to EC 1.14.13.39 (nitric oxide synthase) inhibitor." []
synonym: "EC 1.14.13.39 (nitric oxide synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61908 ! has exposure stimulus EC 1.14.13.39 (nitric oxide synthase) inhibitor
relationship: RO:0002309 CHEBI:61908 ! has exposure stimulus EC 1.14.13.39 (nitric oxide synthase) inhibitor

[Term]
id: ECTO:9001920
name: exposure to microtubule-stabilising agent
def: "An exposure to microtubule-stabilising agent." []
synonym: "microtubule-stabilising agent exposure" EXACT []
is_a: ECTO:9001915 ! exposure to tubulin modulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61950 ! has exposure stimulus microtubule-stabilising agent
relationship: RO:0002309 CHEBI:61950 ! has exposure stimulus microtubule-stabilising agent

[Term]
id: ECTO:9001921
name: exposure to microtubule-destabilising agent
def: "An exposure to microtubule-destabilising agent." []
synonym: "microtubule-destabilising agent exposure" EXACT []
is_a: ECTO:9001915 ! exposure to tubulin modulator
is_a: ECTO:9001959 ! exposure to antimitotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61951 ! has exposure stimulus microtubule-destabilising agent
relationship: RO:0002309 CHEBI:61951 ! has exposure stimulus microtubule-destabilising agent

[Term]
id: ECTO:9001922
name: exposure to metabotropic glutamate receptor agonist
def: "An exposure to metabotropic glutamate receptor agonist." []
synonym: "metabotropic glutamate receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61966 ! has exposure stimulus metabotropic glutamate receptor agonist
relationship: RO:0002309 CHEBI:61966 ! has exposure stimulus metabotropic glutamate receptor agonist

[Term]
id: ECTO:9001923
name: exposure to acyl donor
def: "An exposure to acyl donor." []
synonym: "acyl donor exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62049 ! has exposure stimulus acyl donor
relationship: RO:0002309 CHEBI:62049 ! has exposure stimulus acyl donor

[Term]
id: ECTO:9001924
name: exposure to allelochemical
def: "An exposure to allelochemical." []
synonym: "allelochemical exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62215 ! has exposure stimulus allelochemical
relationship: RO:0002309 CHEBI:62215 ! has exposure stimulus allelochemical

[Term]
id: ECTO:9001926
name: exposure to fuel additive
def: "An exposure to fuel additive." []
synonym: "fuel additive exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62803 ! has exposure stimulus fuel additive
relationship: RO:0002309 CHEBI:62803 ! has exposure stimulus fuel additive

[Term]
id: ECTO:9001927
name: exposure to hepatoprotective agent
def: "An exposure to hepatoprotective agent." []
synonym: "hepatoprotective agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62868 ! has exposure stimulus hepatoprotective agent
relationship: RO:0002309 CHEBI:62868 ! has exposure stimulus hepatoprotective agent

[Term]
id: ECTO:9001928
name: exposure to EC 1.2.3.1 (aldehyde oxidase) inhibitor
def: "An exposure to EC 1.2.3.1 (aldehyde oxidase) inhibitor." []
synonym: "EC 1.2.3.1 (aldehyde oxidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62872 ! has exposure stimulus EC 1.2.3.1 (aldehyde oxidase) inhibitor
relationship: RO:0002309 CHEBI:62872 ! has exposure stimulus EC 1.2.3.1 (aldehyde oxidase) inhibitor

[Term]
id: ECTO:9001929
name: exposure to EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
def: "An exposure to EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor." []
synonym: "EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62913 ! has exposure stimulus EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
relationship: RO:0002309 CHEBI:62913 ! has exposure stimulus EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor

[Term]
id: ECTO:9001930
name: exposure to food emulsifier
def: "An exposure to food emulsifier." []
synonym: "food emulsifier exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63047 ! has exposure stimulus food emulsifier
relationship: RO:0002309 CHEBI:63047 ! has exposure stimulus food emulsifier

[Term]
id: ECTO:9001931
name: exposure to sphingosine-1-phosphate receptor agonist
def: "An exposure to sphingosine-1-phosphate receptor agonist." []
synonym: "sphingosine-1-phosphate receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63114 ! has exposure stimulus sphingosine-1-phosphate receptor agonist
relationship: RO:0002309 CHEBI:63114 ! has exposure stimulus sphingosine-1-phosphate receptor agonist

[Term]
id: ECTO:9001932
name: exposure to EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor
def: "An exposure to EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor." []
synonym: "EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63158 ! has exposure stimulus EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor
relationship: RO:0002309 CHEBI:63158 ! has exposure stimulus EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor

[Term]
id: ECTO:9001933
name: exposure to T-cell proliferation inhibitor
def: "An exposure to T-cell proliferation inhibitor." []
synonym: "T-cell proliferation inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63173 ! has exposure stimulus T-cell proliferation inhibitor
relationship: RO:0002309 CHEBI:63173 ! has exposure stimulus T-cell proliferation inhibitor

[Term]
id: ECTO:9001934
name: exposure to reducing agent
def: "An exposure to reducing agent." []
synonym: "reducing agent exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63247 ! has exposure stimulus reducing agent
relationship: RO:0002309 CHEBI:63247 ! has exposure stimulus reducing agent

[Term]
id: ECTO:9001935
name: exposure to oxidising agent
def: "An exposure to oxidising agent." []
synonym: "oxidising agent exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63248 ! has exposure stimulus oxidising agent
relationship: RO:0002309 CHEBI:63248 ! has exposure stimulus oxidising agent

[Term]
id: ECTO:9001936
name: exposure to EC 3.1.3.1 (alkaline phosphatase) inhibitor
def: "An exposure to EC 3.1.3.1 (alkaline phosphatase) inhibitor." []
synonym: "EC 3.1.3.1 (alkaline phosphatase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63332 ! has exposure stimulus EC 3.1.3.1 (alkaline phosphatase) inhibitor
relationship: RO:0002309 CHEBI:63332 ! has exposure stimulus EC 3.1.3.1 (alkaline phosphatase) inhibitor

[Term]
id: ECTO:9001937
name: exposure to explosive
def: "An exposure to explosive." []
synonym: "explosive exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63490 ! has exposure stimulus explosive
relationship: RO:0002309 CHEBI:63490 ! has exposure stimulus explosive

[Term]
id: ECTO:9001938
name: exposure to neuroprotective agent
def: "An exposure to neuroprotective agent." []
synonym: "neuroprotective agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63726 ! has exposure stimulus neuroprotective agent
relationship: RO:0002309 CHEBI:63726 ! has exposure stimulus neuroprotective agent

[Term]
id: ECTO:9001939
name: exposure to retinoid X receptor agonist
def: "An exposure to retinoid X receptor agonist." []
synonym: "retinoid X receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63794 ! has exposure stimulus retinoid X receptor agonist
relationship: RO:0002309 CHEBI:63794 ! has exposure stimulus retinoid X receptor agonist

[Term]
id: ECTO:9001940
name: exposure to Hsp90 inhibitor
def: "An exposure to Hsp90 inhibitor." []
synonym: "Hsp90 inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63962 ! has exposure stimulus Hsp90 inhibitor
relationship: RO:0002309 CHEBI:63962 ! has exposure stimulus Hsp90 inhibitor

[Term]
id: ECTO:9001941
name: exposure to protein kinase C agonist
def: "An exposure to protein kinase C agonist." []
synonym: "protein kinase C agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64018 ! has exposure stimulus protein kinase C agonist
relationship: RO:0002309 CHEBI:64018 ! has exposure stimulus protein kinase C agonist

[Term]
id: ECTO:9001942
name: exposure to food additive
def: "An exposure to food additive." []
synonym: "food additive exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
is_a: ECTO:0000487 ! exposure to chemical with chemical role
is_a: ECTO:9002063 ! exposure to food component
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64047 ! has exposure stimulus food additive
relationship: RO:0002309 CHEBI:64047 ! has exposure stimulus food additive

[Term]
id: ECTO:9001943
name: exposure to food acidity regulator
def: "An exposure to food acidity regulator." []
synonym: "food acidity regulator exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64049 ! has exposure stimulus food acidity regulator
relationship: RO:0002309 CHEBI:64049 ! has exposure stimulus food acidity regulator

[Term]
id: ECTO:9001944
name: exposure to EC 2.5.1.58 (protein farnesyltransferase) inhibitor
def: "An exposure to EC 2.5.1.58 (protein farnesyltransferase) inhibitor." []
synonym: "EC 2.5.1.58 (protein farnesyltransferase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64133 ! has exposure stimulus EC 2.5.1.58 (protein farnesyltransferase) inhibitor
relationship: RO:0002309 CHEBI:64133 ! has exposure stimulus EC 2.5.1.58 (protein farnesyltransferase) inhibitor

[Term]
id: ECTO:9001945
name: exposure to EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor
def: "An exposure to EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor." []
synonym: "EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64237 ! has exposure stimulus EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor
relationship: RO:0002309 CHEBI:64237 ! has exposure stimulus EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor

[Term]
id: ECTO:9001946
name: exposure to MALDI matrix material
def: "An exposure to MALDI matrix material." []
synonym: "MALDI matrix material exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64345 ! has exposure stimulus MALDI matrix material
relationship: RO:0002309 CHEBI:64345 ! has exposure stimulus MALDI matrix material

[Term]
id: ECTO:9001947
name: exposure to EC 3.4.22.38 (cathepsin K) inhibitor
def: "An exposure to EC 3.4.22.38 (cathepsin K) inhibitor." []
synonym: "EC 3.4.22.38 (cathepsin K) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64406 ! has exposure stimulus EC 3.4.22.38 (cathepsin K) inhibitor
relationship: RO:0002309 CHEBI:64406 ! has exposure stimulus EC 3.4.22.38 (cathepsin K) inhibitor

[Term]
id: ECTO:9001948
name: exposure to EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor
def: "An exposure to EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor." []
synonym: "EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64411 ! has exposure stimulus EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor
relationship: RO:0002309 CHEBI:64411 ! has exposure stimulus EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor

[Term]
id: ECTO:9001949
name: exposure to EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
def: "An exposure to EC 1.3.1.43 (arogenate dehydrogenase) inhibitor." []
synonym: "EC 1.3.1.43 (arogenate dehydrogenase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64416 ! has exposure stimulus EC 1.3.1.43 (arogenate dehydrogenase) inhibitor
relationship: RO:0002309 CHEBI:64416 ! has exposure stimulus EC 1.3.1.43 (arogenate dehydrogenase) inhibitor

[Term]
id: ECTO:9001950
name: exposure to monolignol
def: "An exposure to monolignol." []
synonym: "monolignol exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64477 ! has exposure stimulus monolignol
relationship: RO:0002309 CHEBI:64477 ! has exposure stimulus monolignol

[Term]
id: ECTO:9001951
name: exposure to EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor
def: "An exposure to EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor." []
synonym: "EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64570 ! has exposure stimulus EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor
relationship: RO:0002309 CHEBI:64570 ! has exposure stimulus EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor

[Term]
id: ECTO:9001952
name: exposure to NMDA receptor agonist
def: "An exposure to NMDA receptor agonist." []
synonym: "NMDA receptor agonist exposure" EXACT []
is_a: ECTO:9001832 ! exposure to excitatory amino acid agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64571 ! has exposure stimulus NMDA receptor agonist
relationship: RO:0002309 CHEBI:64571 ! has exposure stimulus NMDA receptor agonist

[Term]
id: ECTO:9001953
name: exposure to flour treatment agent
def: "An exposure to flour treatment agent." []
synonym: "flour treatment agent exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64577 ! has exposure stimulus flour treatment agent
relationship: RO:0002309 CHEBI:64577 ! has exposure stimulus flour treatment agent

[Term]
id: ECTO:9001954
name: exposure to uremic toxin
def: "An exposure to uremic toxin." []
synonym: "uremic toxin exposure" EXACT []
is_a: ECTO:0000537 ! exposure to toxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64584 ! has exposure stimulus uremic toxin
relationship: RO:0002309 CHEBI:64584 ! has exposure stimulus uremic toxin

[Term]
id: ECTO:9001955
name: exposure to glycine transporter 1 inhibitor
def: "An exposure to glycine transporter 1 inhibitor." []
synonym: "glycine transporter 1 inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64588 ! has exposure stimulus glycine transporter 1 inhibitor
relationship: RO:0002309 CHEBI:64588 ! has exposure stimulus glycine transporter 1 inhibitor

[Term]
id: ECTO:9001956
name: exposure to glycine receptor agonist
def: "An exposure to glycine receptor agonist." []
synonym: "glycine receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64589 ! has exposure stimulus glycine receptor agonist
relationship: RO:0002309 CHEBI:64589 ! has exposure stimulus glycine receptor agonist

[Term]
id: ECTO:9001957
name: exposure to EC 1.8.1.9 (thioredoxin reductase) inhibitor
def: "An exposure to EC 1.8.1.9 (thioredoxin reductase) inhibitor." []
synonym: "EC 1.8.1.9 (thioredoxin reductase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64670 ! has exposure stimulus EC 1.8.1.9 (thioredoxin reductase) inhibitor
relationship: RO:0002309 CHEBI:64670 ! has exposure stimulus EC 1.8.1.9 (thioredoxin reductase) inhibitor

[Term]
id: ECTO:9001958
name: exposure to EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
def: "An exposure to EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor." []
synonym: "EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor exposure" EXACT []
is_a: ECTO:9001839 ! exposure to EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64763 ! has exposure stimulus EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
relationship: RO:0002309 CHEBI:64763 ! has exposure stimulus EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor

[Term]
id: ECTO:9001959
name: exposure to antimitotic
def: "An exposure to antimitotic." []
synonym: "antimitotic exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64911 ! has exposure stimulus antimitotic
relationship: RO:0002309 CHEBI:64911 ! has exposure stimulus antimitotic

[Term]
id: ECTO:9001960
name: exposure to antimycobacterial drug
def: "An exposure to antimycobacterial drug." []
synonym: "antimycobacterial drug exposure" EXACT []
is_a: ECTO:9001757 ! exposure to antibacterial drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64912 ! has exposure stimulus antimycobacterial drug
relationship: RO:0002309 CHEBI:64912 ! has exposure stimulus antimycobacterial drug

[Term]
id: ECTO:9001961
name: exposure to serine protease inhibitor
def: "An exposure to serine protease inhibitor." []
synonym: "serine protease inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64926 ! has exposure stimulus serine protease inhibitor
relationship: RO:0002309 CHEBI:64926 ! has exposure stimulus serine protease inhibitor

[Term]
id: ECTO:9001962
name: exposure to anti-HIV agent
def: "An exposure to anti-HIV agent." []
synonym: "anti-HIV agent exposure" EXACT []
is_a: ECTO:9001648 ! exposure to antiviral agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64946 ! has exposure stimulus anti-HIV agent
relationship: RO:0002309 CHEBI:64946 ! has exposure stimulus anti-HIV agent

[Term]
id: ECTO:9001963
name: exposure to anti-HSV-1 agent
def: "An exposure to anti-HSV-1 agent." []
synonym: "anti-HSV-1 agent exposure" EXACT []
is_a: ECTO:9001648 ! exposure to antiviral agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64953 ! has exposure stimulus anti-HSV-1 agent
relationship: RO:0002309 CHEBI:64953 ! has exposure stimulus anti-HSV-1 agent

[Term]
id: ECTO:9001964
name: exposure to EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
def: "An exposure to EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor." []
synonym: "EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor exposure" EXACT []
is_a: ECTO:9001754 ! exposure to lipoxygenase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64964 ! has exposure stimulus EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
relationship: RO:0002309 CHEBI:64964 ! has exposure stimulus EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor

[Term]
id: ECTO:9001965
name: exposure to EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
def: "An exposure to EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor." []
synonym: "EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor exposure" EXACT []
is_a: ECTO:9001754 ! exposure to lipoxygenase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64996 ! has exposure stimulus EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
relationship: RO:0002309 CHEBI:64996 ! has exposure stimulus EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor

[Term]
id: ECTO:9001966
name: exposure to EC 3.1.1.3 (triacylglycerol lipase) inhibitor
def: "An exposure to EC 3.1.1.3 (triacylglycerol lipase) inhibitor." []
synonym: "EC 3.1.1.3 (triacylglycerol lipase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65001 ! has exposure stimulus EC 3.1.1.3 (triacylglycerol lipase) inhibitor
relationship: RO:0002309 CHEBI:65001 ! has exposure stimulus EC 3.1.1.3 (triacylglycerol lipase) inhibitor

[Term]
id: ECTO:9001967
name: exposure to EC 4.1.1.19 (arginine decarboxylase) inhibitor
def: "An exposure to EC 4.1.1.19 (arginine decarboxylase) inhibitor." []
synonym: "EC 4.1.1.19 (arginine decarboxylase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65053 ! has exposure stimulus EC 4.1.1.19 (arginine decarboxylase) inhibitor
relationship: RO:0002309 CHEBI:65053 ! has exposure stimulus EC 4.1.1.19 (arginine decarboxylase) inhibitor

[Term]
id: ECTO:9001968
name: exposure to EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
def: "An exposure to EC 3.1.3.11 (fructose-bisphosphatase) inhibitor." []
synonym: "EC 3.1.3.11 (fructose-bisphosphatase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65056 ! has exposure stimulus EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
relationship: RO:0002309 CHEBI:65056 ! has exposure stimulus EC 3.1.3.11 (fructose-bisphosphatase) inhibitor

[Term]
id: ECTO:9001969
name: exposure to adenosine A1 receptor agonist
def: "An exposure to adenosine A1 receptor agonist." []
synonym: "adenosine A1 receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65057 ! has exposure stimulus adenosine A1 receptor agonist
relationship: RO:0002309 CHEBI:65057 ! has exposure stimulus adenosine A1 receptor agonist

[Term]
id: ECTO:9001970
name: exposure to EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor
def: "An exposure to EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor." []
synonym: "EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65064 ! has exposure stimulus EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor
relationship: RO:0002309 CHEBI:65064 ! has exposure stimulus EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor

[Term]
id: ECTO:9001971
name: exposure to EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor
def: "An exposure to EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor." []
synonym: "EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65065 ! has exposure stimulus EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor
relationship: RO:0002309 CHEBI:65065 ! has exposure stimulus EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor

[Term]
id: ECTO:9001972
name: exposure to first generation antipsychotic
def: "An exposure to first generation antipsychotic." []
synonym: "first generation antipsychotic exposure" EXACT []
is_a: ECTO:9001721 ! exposure to antipsychotic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65190 ! has exposure stimulus first generation antipsychotic
relationship: RO:0002309 CHEBI:65190 ! has exposure stimulus first generation antipsychotic

[Term]
id: ECTO:9001973
name: exposure to second generation antipsychotic
def: "An exposure to second generation antipsychotic." []
synonym: "second generation antipsychotic exposure" EXACT []
is_a: ECTO:9001721 ! exposure to antipsychotic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65191 ! has exposure stimulus second generation antipsychotic
relationship: RO:0002309 CHEBI:65191 ! has exposure stimulus second generation antipsychotic

[Term]
id: ECTO:9001974
name: exposure to EC 3.4.21.5 (thrombin) inhibitor
def: "An exposure to EC 3.4.21.5 (thrombin) inhibitor." []
synonym: "EC 3.4.21.5 (thrombin) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65232 ! has exposure stimulus EC 3.4.21.5 (thrombin) inhibitor
relationship: RO:0002309 CHEBI:65232 ! has exposure stimulus EC 3.4.21.5 (thrombin) inhibitor

[Term]
id: ECTO:9001975
name: exposure to antimicrobial food preservative
def: "An exposure to antimicrobial food preservative." []
synonym: "antimicrobial food preservative exposure" EXACT []
is_a: ECTO:0000544 ! exposure to antimicrobial agent
is_a: ECTO:9002130 ! exposure to food preservative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65256 ! has exposure stimulus antimicrobial food preservative
relationship: RO:0002309 CHEBI:65256 ! has exposure stimulus antimicrobial food preservative

[Term]
id: ECTO:9001976
name: exposure to GABA antagonist
def: "An exposure to GABA antagonist." []
synonym: "GABA antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65259 ! has exposure stimulus GABA antagonist
relationship: RO:0002309 CHEBI:65259 ! has exposure stimulus GABA antagonist

[Term]
id: ECTO:9001977
name: exposure to antidyskinesia agent
def: "An exposure to antidyskinesia agent." []
synonym: "antidyskinesia agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66956 ! has exposure stimulus antidyskinesia agent
relationship: RO:0002309 CHEBI:66956 ! has exposure stimulus antidyskinesia agent

[Term]
id: ECTO:9001978
name: exposure to nootropic agent
def: "An exposure to nootropic agent." []
synonym: "nootropic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66980 ! has exposure stimulus nootropic agent
relationship: RO:0002309 CHEBI:66980 ! has exposure stimulus nootropic agent

[Term]
id: ECTO:9001979
name: exposure to radiation protective agent
def: "An exposure to radiation protective agent." []
synonym: "radiation protective agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66987 ! has exposure stimulus radiation protective agent
relationship: RO:0002309 CHEBI:66987 ! has exposure stimulus radiation protective agent

[Term]
id: ECTO:9001980
name: exposure to tocolytic agent
def: "An exposure to tocolytic agent." []
synonym: "tocolytic agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66993 ! has exposure stimulus tocolytic agent
relationship: RO:0002309 CHEBI:66993 ! has exposure stimulus tocolytic agent

[Term]
id: ECTO:9001981
name: exposure to cannabinoid receptor agonist
def: "An exposure to cannabinoid receptor agonist." []
synonym: "cannabinoid receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67072 ! has exposure stimulus cannabinoid receptor agonist
relationship: RO:0002309 CHEBI:67072 ! has exposure stimulus cannabinoid receptor agonist

[Term]
id: ECTO:9001982
name: exposure to anti-inflammatory agent
def: "An exposure to anti-inflammatory agent." []
synonym: "anti-inflammatory agent exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67079 ! has exposure stimulus anti-inflammatory agent
relationship: RO:0002309 CHEBI:67079 ! has exposure stimulus anti-inflammatory agent

[Term]
id: ECTO:9001983
name: exposure to ryanodine receptor agonist
def: "An exposure to ryanodine receptor agonist." []
synonym: "ryanodine receptor agonist exposure" EXACT []
is_a: ECTO:9001792 ! exposure to ryanodine receptor modulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67114 ! has exposure stimulus ryanodine receptor agonist
relationship: RO:0002309 CHEBI:67114 ! has exposure stimulus ryanodine receptor agonist

[Term]
id: ECTO:9001984
name: exposure to EC 3.4.24.3 (microbial collagenase) inhibitor
def: "An exposure to EC 3.4.24.3 (microbial collagenase) inhibitor." []
synonym: "EC 3.4.24.3 (microbial collagenase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67189 ! has exposure stimulus EC 3.4.24.3 (microbial collagenase) inhibitor
relationship: RO:0002309 CHEBI:67189 ! has exposure stimulus EC 3.4.24.3 (microbial collagenase) inhibitor

[Term]
id: ECTO:9001985
name: exposure to gap junctional intercellular communication inhibitor
def: "An exposure to gap junctional intercellular communication inhibitor." []
synonym: "gap junctional intercellular communication inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67195 ! has exposure stimulus gap junctional intercellular communication inhibitor
relationship: RO:0002309 CHEBI:67195 ! has exposure stimulus gap junctional intercellular communication inhibitor

[Term]
id: ECTO:9001986
name: exposure to retinoic acid receptor agonist
def: "An exposure to retinoic acid receptor agonist." []
synonym: "retinoic acid receptor agonist exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67198 ! has exposure stimulus retinoic acid receptor agonist
relationship: RO:0002309 CHEBI:67198 ! has exposure stimulus retinoic acid receptor agonist

[Term]
id: ECTO:9001987
name: exposure to AP-1 antagonist
def: "An exposure to AP-1 antagonist." []
synonym: "AP-1 antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67199 ! has exposure stimulus AP-1 antagonist
relationship: RO:0002309 CHEBI:67199 ! has exposure stimulus AP-1 antagonist

[Term]
id: ECTO:9001988
name: exposure to provitamin A
def: "An exposure to provitamin A." []
synonym: "provitamin A exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67200 ! has exposure stimulus provitamin A
relationship: RO:0002309 CHEBI:67200 ! has exposure stimulus provitamin A

[Term]
id: ECTO:9001989
name: exposure to mTOR inhibitor
def: "An exposure to mTOR inhibitor." []
synonym: "mTOR inhibitor exposure" EXACT []
is_a: ECTO:9001763 ! exposure to protein kinase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68481 ! has exposure stimulus mTOR inhibitor
relationship: RO:0002309 CHEBI:68481 ! has exposure stimulus mTOR inhibitor

[Term]
id: ECTO:9001990
name: exposure to apoptosis inhibitor
def: "An exposure to apoptosis inhibitor." []
synonym: "apoptosis inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68494 ! has exposure stimulus apoptosis inhibitor
relationship: RO:0002309 CHEBI:68494 ! has exposure stimulus apoptosis inhibitor

[Term]
id: ECTO:9001991
name: exposure to apoptosis inducer
def: "An exposure to apoptosis inducer." []
synonym: "apoptosis inducer exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68495 ! has exposure stimulus apoptosis inducer
relationship: RO:0002309 CHEBI:68495 ! has exposure stimulus apoptosis inducer

[Term]
id: ECTO:9001992
name: exposure to glutathione depleting agent
def: "An exposure to glutathione depleting agent." []
synonym: "glutathione depleting agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68509 ! has exposure stimulus glutathione depleting agent
relationship: RO:0002309 CHEBI:68509 ! has exposure stimulus glutathione depleting agent

[Term]
id: ECTO:9001993
name: exposure to P2Y12 receptor antagonist
def: "An exposure to P2Y12 receptor antagonist." []
synonym: "P2Y12 receptor antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68563 ! has exposure stimulus P2Y12 receptor antagonist
relationship: RO:0002309 CHEBI:68563 ! has exposure stimulus P2Y12 receptor antagonist

[Term]
id: ECTO:9001994
name: exposure to progesterone receptor agonist
def: "An exposure to progesterone receptor agonist." []
synonym: "progesterone receptor agonist exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70709 ! has exposure stimulus progesterone receptor agonist
relationship: RO:0002309 CHEBI:70709 ! has exposure stimulus progesterone receptor agonist

[Term]
id: ECTO:9001995
name: exposure to cell dedifferentiation agent
def: "An exposure to cell dedifferentiation agent." []
synonym: "cell dedifferentiation agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70724 ! has exposure stimulus cell dedifferentiation agent
relationship: RO:0002309 CHEBI:70724 ! has exposure stimulus cell dedifferentiation agent

[Term]
id: ECTO:9001996
name: exposure to adenosine A3 receptor antagonist
def: "An exposure to adenosine A3 receptor antagonist." []
synonym: "adenosine A3 receptor antagonist exposure" EXACT []
is_a: ECTO:9002006 ! exposure to adenosine receptor antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70725 ! has exposure stimulus adenosine A3 receptor antagonist
relationship: RO:0002309 CHEBI:70725 ! has exposure stimulus adenosine A3 receptor antagonist

[Term]
id: ECTO:9001997
name: exposure to actin polymerisation inhibitor
def: "An exposure to actin polymerisation inhibitor." []
synonym: "actin polymerisation inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70728 ! has exposure stimulus actin polymerisation inhibitor
relationship: RO:0002309 CHEBI:70728 ! has exposure stimulus actin polymerisation inhibitor

[Term]
id: ECTO:9001998
name: exposure to Aurora kinase inhibitor
def: "An exposure to Aurora kinase inhibitor." []
synonym: "Aurora kinase inhibitor exposure" EXACT []
is_a: ECTO:9001763 ! exposure to protein kinase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70770 ! has exposure stimulus Aurora kinase inhibitor
relationship: RO:0002309 CHEBI:70770 ! has exposure stimulus Aurora kinase inhibitor

[Term]
id: ECTO:9001999
name: exposure to capsaicin receptor antagonist
def: "An exposure to capsaicin receptor antagonist." []
synonym: "capsaicin receptor antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70774 ! has exposure stimulus capsaicin receptor antagonist
relationship: RO:0002309 CHEBI:70774 ! has exposure stimulus capsaicin receptor antagonist

[Term]
id: ECTO:9002000
name: exposure to PPARalpha agonist
def: "An exposure to PPARalpha agonist." []
synonym: "PPARalpha agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70782 ! has exposure stimulus PPARalpha agonist
relationship: RO:0002309 CHEBI:70782 ! has exposure stimulus PPARalpha agonist

[Term]
id: ECTO:9002001
name: exposure to EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor
def: "An exposure to EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor." []
synonym: "EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70817 ! has exposure stimulus EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor
relationship: RO:0002309 CHEBI:70817 ! has exposure stimulus EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor

[Term]
id: ECTO:9002002
name: exposure to antileishmanial agent
def: "An exposure to antileishmanial agent." []
synonym: "antileishmanial agent exposure" EXACT []
is_a: ECTO:9001751 ! exposure to antiprotozoal drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70868 ! has exposure stimulus antileishmanial agent
relationship: RO:0002309 CHEBI:70868 ! has exposure stimulus antileishmanial agent

[Term]
id: ECTO:9002003
name: exposure to G-protein-coupled receptor agonist
def: "An exposure to G-protein-coupled receptor agonist." []
synonym: "G-protein-coupled receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70998 ! has exposure stimulus G-protein-coupled receptor agonist
relationship: RO:0002309 CHEBI:70998 ! has exposure stimulus G-protein-coupled receptor agonist

[Term]
id: ECTO:9002004
name: exposure to Sir2 inhibitor
def: "An exposure to Sir2 inhibitor." []
synonym: "Sir2 inhibitor exposure" EXACT []
is_a: ECTO:9001918 ! exposure to EC 3.5.1.98 (histone deacetylase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71181 ! has exposure stimulus Sir2 inhibitor
relationship: RO:0002309 CHEBI:71181 ! has exposure stimulus Sir2 inhibitor

[Term]
id: ECTO:9002005
name: exposure to prohormone
def: "An exposure to prohormone." []
synonym: "prohormone exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71212 ! has exposure stimulus prohormone
relationship: RO:0002309 CHEBI:71212 ! has exposure stimulus prohormone

[Term]
id: ECTO:9002006
name: exposure to adenosine receptor antagonist
def: "An exposure to adenosine receptor antagonist." []
synonym: "adenosine receptor antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71232 ! has exposure stimulus adenosine receptor antagonist
relationship: RO:0002309 CHEBI:71232 ! has exposure stimulus adenosine receptor antagonist

[Term]
id: ECTO:9002007
name: exposure to EC 2.3.1.85 (fatty acid synthase) inhibitor
def: "An exposure to EC 2.3.1.85 (fatty acid synthase) inhibitor." []
synonym: "EC 2.3.1.85 (fatty acid synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71476 ! has exposure stimulus EC 2.3.1.85 (fatty acid synthase) inhibitor
relationship: RO:0002309 CHEBI:71476 ! has exposure stimulus EC 2.3.1.85 (fatty acid synthase) inhibitor

[Term]
id: ECTO:9002008
name: exposure to virulence factor
def: "An exposure to virulence factor." []
synonym: "virulence factor exposure" EXACT []
is_a: ECTO:0000537 ! exposure to toxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72316 ! has exposure stimulus virulence factor
relationship: RO:0002309 CHEBI:72316 ! has exposure stimulus virulence factor

[Term]
id: ECTO:9002009
name: exposure to aryl hydrocarbon receptor agonist
def: "An exposure to aryl hydrocarbon receptor agonist." []
synonym: "aryl hydrocarbon receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72768 ! has exposure stimulus aryl hydrocarbon receptor agonist
relationship: RO:0002309 CHEBI:72768 ! has exposure stimulus aryl hydrocarbon receptor agonist

[Term]
id: ECTO:9002010
name: exposure to EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors
def: "An exposure to EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor." []
synonym: "EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73181 ! has exposure stimulus EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor
relationship: RO:0002309 CHEBI:73181 ! has exposure stimulus EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor

[Term]
id: ECTO:9002011
name: exposure to plant activator
def: "An exposure to plant activator." []
synonym: "plant activator exposure" EXACT []
is_a: ECTO:9001696 ! exposure to agrochemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73182 ! has exposure stimulus plant activator
relationship: RO:0002309 CHEBI:73182 ! has exposure stimulus plant activator

[Term]
id: ECTO:9002012
name: exposure to abscisic acid receptor agonist
def: "An exposure to abscisic acid receptor agonist." []
synonym: "abscisic acid receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73191 ! has exposure stimulus abscisic acid receptor agonist
relationship: RO:0002309 CHEBI:73191 ! has exposure stimulus abscisic acid receptor agonist

[Term]
id: ECTO:9002013
name: exposure to NF-kappaB inhibitor
def: "An exposure to NF-kappaB inhibitor." []
synonym: "NF-kappaB inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73240 ! has exposure stimulus NF-kappaB inhibitor
relationship: RO:0002309 CHEBI:73240 ! has exposure stimulus NF-kappaB inhibitor

[Term]
id: ECTO:9002014
name: exposure to cyclooxygenase 3 inhibitor
def: "An exposure to cyclooxygenase 3 inhibitor." []
synonym: "cyclooxygenase 3 inhibitor exposure" EXACT []
is_a: ECTO:9001735 ! exposure to EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73263 ! has exposure stimulus cyclooxygenase 3 inhibitor
relationship: RO:0002309 CHEBI:73263 ! has exposure stimulus cyclooxygenase 3 inhibitor

[Term]
id: ECTO:9002015
name: exposure to ultraviolet filter
def: "An exposure to ultraviolet filter." []
synonym: "ultraviolet filter exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73335 ! has exposure stimulus ultraviolet filter
relationship: RO:0002309 CHEBI:73335 ! has exposure stimulus ultraviolet filter

[Term]
id: ECTO:9002016
name: exposure to vulnerary
def: "An exposure to vulnerary." []
synonym: "vulnerary exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73336 ! has exposure stimulus vulnerary
relationship: RO:0002309 CHEBI:73336 ! has exposure stimulus vulnerary

[Term]
id: ECTO:9002017
name: exposure to methionine aminopeptidase 2 inhibitor
def: "An exposure to methionine aminopeptidase 2 inhibitor." []
synonym: "methionine aminopeptidase 2 inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73361 ! has exposure stimulus methionine aminopeptidase 2 inhibitor
relationship: RO:0002309 CHEBI:73361 ! has exposure stimulus methionine aminopeptidase 2 inhibitor

[Term]
id: ECTO:9002018
name: exposure to EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor
def: "An exposure to EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor." []
synonym: "EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74213 ! has exposure stimulus EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor
relationship: RO:0002309 CHEBI:74213 ! has exposure stimulus EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor

[Term]
id: ECTO:9002019
name: exposure to antidote to paracetamol poisoning
def: "An exposure to antidote to paracetamol poisoning." []
synonym: "antidote to paracetamol poisoning exposure" EXACT []
is_a: ECTO:9001840 ! exposure to antidote
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74529 ! has exposure stimulus antidote to paracetamol poisoning
relationship: RO:0002309 CHEBI:74529 ! has exposure stimulus antidote to paracetamol poisoning

[Term]
id: ECTO:9002020
name: exposure to antidote to curare poisoning
def: "An exposure to antidote to curare poisoning." []
synonym: "antidote to curare poisoning exposure" EXACT []
is_a: ECTO:9001840 ! exposure to antidote
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74530 ! has exposure stimulus antidote to curare poisoning
relationship: RO:0002309 CHEBI:74530 ! has exposure stimulus antidote to curare poisoning

[Term]
id: ECTO:9002021
name: exposure to astringent
def: "An exposure to astringent." []
synonym: "astringent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74783 ! has exposure stimulus astringent
relationship: RO:0002309 CHEBI:74783 ! has exposure stimulus astringent

[Term]
id: ECTO:9002022
name: exposure to chromogenic compound
def: "An exposure to chromogenic compound." []
synonym: "chromogenic compound exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75050 ! has exposure stimulus chromogenic compound
relationship: RO:0002309 CHEBI:75050 ! has exposure stimulus chromogenic compound

[Term]
id: ECTO:9002023
name: exposure to EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor
def: "An exposure to EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor." []
synonym: "EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75190 ! has exposure stimulus EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor
relationship: RO:0002309 CHEBI:75190 ! has exposure stimulus EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor

[Term]
id: ECTO:9002024
name: exposure to ergosterol biosynthesis inhibitor
def: "An exposure to ergosterol biosynthesis inhibitor." []
synonym: "ergosterol biosynthesis inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75282 ! has exposure stimulus ergosterol biosynthesis inhibitor
relationship: RO:0002309 CHEBI:75282 ! has exposure stimulus ergosterol biosynthesis inhibitor

[Term]
id: ECTO:9002025
name: exposure to EC 1.11.1.6 (catalase) inhibitor
def: "An exposure to EC 1.11.1.6 (catalase) inhibitor." []
synonym: "EC 1.11.1.6 (catalase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75380 ! has exposure stimulus EC 1.11.1.6 (catalase) inhibitor
relationship: RO:0002309 CHEBI:75380 ! has exposure stimulus EC 1.11.1.6 (catalase) inhibitor

[Term]
id: ECTO:9002026
name: exposure to B vitamin
def: "An exposure to B vitamin." []
synonym: "B vitamin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75769 ! has exposure stimulus B vitamin
relationship: RO:0002309 CHEBI:75769 ! has exposure stimulus B vitamin

[Term]
id: ECTO:9002027
name: exposure to xenobiotic metabolite
def: "An exposure to xenobiotic metabolite." []
synonym: "xenobiotic metabolite exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76206 ! has exposure stimulus xenobiotic metabolite
relationship: RO:0002309 CHEBI:76206 ! has exposure stimulus xenobiotic metabolite

[Term]
id: ECTO:9002028
name: exposure to greenhouse gas
def: "An exposure to greenhouse gas." []
synonym: "greenhouse gas exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76413 ! has exposure stimulus greenhouse gas
relationship: RO:0002309 CHEBI:76413 ! has exposure stimulus greenhouse gas

[Term]
id: ECTO:9002029
name: exposure to nephroprotective agent
def: "An exposure to nephroprotective agent." []
synonym: "nephroprotective agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76595 ! has exposure stimulus nephroprotective agent
relationship: RO:0002309 CHEBI:76595 ! has exposure stimulus nephroprotective agent

[Term]
id: ECTO:9002030
name: exposure to EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
def: "An exposure to EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor." []
synonym: "EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor exposure" EXACT []
is_a: ECTO:9001788 ! exposure to tyrosine kinase inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76617 ! has exposure stimulus EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
relationship: RO:0002309 CHEBI:76617 ! has exposure stimulus EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

[Term]
id: ECTO:9002031
name: exposure to EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
def: "An exposure to EC 3.4.21.26 (prolyl oligopeptidase) inhibitor." []
synonym: "EC 3.4.21.26 (prolyl oligopeptidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76779 ! has exposure stimulus EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
relationship: RO:0002309 CHEBI:76779 ! has exposure stimulus EC 3.4.21.26 (prolyl oligopeptidase) inhibitor

[Term]
id: ECTO:9002032
name: exposure to EC 2.5.1.18 (glutathione transferase) inhibitor
def: "An exposure to EC 2.5.1.18 (glutathione transferase) inhibitor." []
synonym: "EC 2.5.1.18 (glutathione transferase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76797 ! has exposure stimulus EC 2.5.1.18 (glutathione transferase) inhibitor
relationship: RO:0002309 CHEBI:76797 ! has exposure stimulus EC 2.5.1.18 (glutathione transferase) inhibitor

[Term]
id: ECTO:9002033
name: exposure to EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor
def: "An exposure to EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor." []
synonym: "EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor exposure" EXACT []
is_a: ECTO:9001839 ! exposure to EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76811 ! has exposure stimulus EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor
relationship: RO:0002309 CHEBI:76811 ! has exposure stimulus EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor

[Term]
id: ECTO:9002034
name: exposure to EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor
def: "An exposure to EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor." []
synonym: "EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76891 ! has exposure stimulus EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor
relationship: RO:0002309 CHEBI:76891 ! has exposure stimulus EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor

[Term]
id: ECTO:9002035
name: exposure to EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor
def: "An exposure to EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor." []
synonym: "EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76893 ! has exposure stimulus EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor
relationship: RO:0002309 CHEBI:76893 ! has exposure stimulus EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor

[Term]
id: ECTO:9002036
name: exposure to xenoestrogen
def: "An exposure to xenoestrogen." []
synonym: "xenoestrogen exposure" EXACT []
is_a: ECTO:9000010 ! exposure to estrogens
is_a: ECTO:9001630 ! exposure to endocrine disruptor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76988 ! has exposure stimulus xenoestrogen
relationship: RO:0002309 CHEBI:76988 ! has exposure stimulus xenoestrogen

[Term]
id: ECTO:9002037
name: exposure to phytoestrogen
def: "An exposure to phytoestrogen." []
synonym: "phytoestrogen exposure" EXACT []
is_a: ECTO:9000010 ! exposure to estrogens
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76989 ! has exposure stimulus phytoestrogen
relationship: RO:0002309 CHEBI:76989 ! has exposure stimulus phytoestrogen

[Term]
id: ECTO:9002038
name: exposure to EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor
def: "An exposure to EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor." []
synonym: "EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77020 ! has exposure stimulus EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor
relationship: RO:0002309 CHEBI:77020 ! has exposure stimulus EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor

[Term]
id: ECTO:9002039
name: exposure to EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor
def: "An exposure to EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor." []
synonym: "EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77024 ! has exposure stimulus EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor
relationship: RO:0002309 CHEBI:77024 ! has exposure stimulus EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor

[Term]
id: ECTO:9002040
name: exposure to expectorant
def: "An exposure to expectorant." []
synonym: "expectorant exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77035 ! has exposure stimulus expectorant
relationship: RO:0002309 CHEBI:77035 ! has exposure stimulus expectorant

[Term]
id: ECTO:9002041
name: exposure to EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor
def: "An exposure to EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor." []
synonym: "EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77111 ! has exposure stimulus EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor
relationship: RO:0002309 CHEBI:77111 ! has exposure stimulus EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor

[Term]
id: ECTO:9002042
name: exposure to EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor
def: "An exposure to EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor." []
synonym: "EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77119 ! has exposure stimulus EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor
relationship: RO:0002309 CHEBI:77119 ! has exposure stimulus EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor

[Term]
id: ECTO:9002043
name: exposure to histological dye
def: "An exposure to histological dye." []
synonym: "histological dye exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77178 ! has exposure stimulus histological dye
relationship: RO:0002309 CHEBI:77178 ! has exposure stimulus histological dye

[Term]
id: ECTO:9002044
name: exposure to food colouring
def: "An exposure to food colouring." []
synonym: "food colouring exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77182 ! has exposure stimulus food colouring
relationship: RO:0002309 CHEBI:77182 ! has exposure stimulus food colouring

[Term]
id: ECTO:9002045
name: exposure to EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
def: "An exposure to EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor." []
synonym: "EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77255 ! has exposure stimulus EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
relationship: RO:0002309 CHEBI:77255 ! has exposure stimulus EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor

[Term]
id: ECTO:9002046
name: exposure to cardioprotective agent
def: "An exposure to cardioprotective agent." []
synonym: "cardioprotective agent exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77307 ! has exposure stimulus cardioprotective agent
relationship: RO:0002309 CHEBI:77307 ! has exposure stimulus cardioprotective agent

[Term]
id: ECTO:9002047
name: exposure to EC 1.1.1.188 (prostaglandin-F synthase) inhibitor
def: "An exposure to EC 1.1.1.188 (prostaglandin-F synthase) inhibitor." []
synonym: "EC 1.1.1.188 (prostaglandin-F synthase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77425 ! has exposure stimulus EC 1.1.1.188 (prostaglandin-F synthase) inhibitor
relationship: RO:0002309 CHEBI:77425 ! has exposure stimulus EC 1.1.1.188 (prostaglandin-F synthase) inhibitor

[Term]
id: ECTO:9002048
name: exposure to EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
def: "An exposure to EC 1.1.1.25 (shikimate dehydrogenase) inhibitor." []
synonym: "EC 1.1.1.25 (shikimate dehydrogenase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77484 ! has exposure stimulus EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
relationship: RO:0002309 CHEBI:77484 ! has exposure stimulus EC 1.1.1.25 (shikimate dehydrogenase) inhibitor

[Term]
id: ECTO:9002049
name: exposure to Maillard reaction product
def: "An exposure to Maillard reaction product." []
synonym: "Maillard reaction product exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77523 ! has exposure stimulus Maillard reaction product
relationship: RO:0002309 CHEBI:77523 ! has exposure stimulus Maillard reaction product

[Term]
id: ECTO:9002050
name: exposure to EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor
def: "An exposure to EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor." []
synonym: "EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77654 ! has exposure stimulus EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor
relationship: RO:0002309 CHEBI:77654 ! has exposure stimulus EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor

[Term]
id: ECTO:9002051
name: exposure to EC 4.3.1.3 (histidine ammonia-lyase) inhibitor
def: "An exposure to EC 4.3.1.3 (histidine ammonia-lyase) inhibitor." []
synonym: "EC 4.3.1.3 (histidine ammonia-lyase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77703 ! has exposure stimulus EC 4.3.1.3 (histidine ammonia-lyase) inhibitor
relationship: RO:0002309 CHEBI:77703 ! has exposure stimulus EC 4.3.1.3 (histidine ammonia-lyase) inhibitor

[Term]
id: ECTO:9002052
name: exposure to EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
def: "An exposure to EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor." []
synonym: "EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77706 ! has exposure stimulus EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
relationship: RO:0002309 CHEBI:77706 ! has exposure stimulus EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor

[Term]
id: ECTO:9002053
name: exposure to persistent organic pollutant
def: "An exposure to persistent organic pollutant." []
synonym: "persistent organic pollutant exposure" EXACT []
is_a: ECTO:0000931 ! exposure to environmental contaminant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77853 ! has exposure stimulus persistent organic pollutant
relationship: RO:0002309 CHEBI:77853 ! has exposure stimulus persistent organic pollutant

[Term]
id: ECTO:9002054
name: exposure to EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
def: "An exposure to EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor." []
synonym: "EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77881 ! has exposure stimulus EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor
relationship: RO:0002309 CHEBI:77881 ! has exposure stimulus EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor

[Term]
id: ECTO:9002056
name: exposure to food antioxidant
def: "An exposure to food antioxidant." []
synonym: "food antioxidant exposure" EXACT []
is_a: ECTO:9001647 ! exposure to antioxidant
is_a: ECTO:9002130 ! exposure to food preservative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77962 ! has exposure stimulus food antioxidant
relationship: RO:0002309 CHEBI:77962 ! has exposure stimulus food antioxidant

[Term]
id: ECTO:9002057
name: exposure to food stabiliser
def: "An exposure to food stabiliser." []
synonym: "food stabiliser exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77966 ! has exposure stimulus food stabiliser
relationship: RO:0002309 CHEBI:77966 ! has exposure stimulus food stabiliser

[Term]
id: ECTO:9002058
name: exposure to food thickening agent
def: "An exposure to food thickening agent." []
synonym: "food thickening agent exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77970 ! has exposure stimulus food thickening agent
relationship: RO:0002309 CHEBI:77970 ! has exposure stimulus food thickening agent

[Term]
id: ECTO:9002059
name: exposure to food packaging gas
def: "An exposure to food packaging gas." []
synonym: "food packaging gas exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77974 ! has exposure stimulus food packaging gas
relationship: RO:0002309 CHEBI:77974 ! has exposure stimulus food packaging gas

[Term]
id: ECTO:9002060
name: exposure to food bleaching agent
def: "An exposure to food bleaching agent." []
synonym: "food bleaching agent exposure" EXACT []
is_a: ECTO:9001701 ! exposure to reagent
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78003 ! has exposure stimulus food bleaching agent
relationship: RO:0002309 CHEBI:78003 ! has exposure stimulus food bleaching agent

[Term]
id: ECTO:9002061
name: exposure to food gelling agent
def: "An exposure to food gelling agent." []
synonym: "food gelling agent exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78016 ! has exposure stimulus food gelling agent
relationship: RO:0002309 CHEBI:78016 ! has exposure stimulus food gelling agent

[Term]
id: ECTO:9002062
name: exposure to food propellant
def: "An exposure to food propellant." []
synonym: "food propellant exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78017 ! has exposure stimulus food propellant
relationship: RO:0002309 CHEBI:78017 ! has exposure stimulus food propellant

[Term]
id: ECTO:9002063
name: exposure to food component
def: "An exposure to food component." []
synonym: "food component exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78295 ! has exposure stimulus food component
relationship: RO:0002309 CHEBI:78295 ! has exposure stimulus food component

[Term]
id: ECTO:9002065
name: exposure to EC 2.7.1.1 (hexokinase) inhibitor
def: "An exposure to EC 2.7.1.1 (hexokinase) inhibitor." []
synonym: "EC 2.7.1.1 (hexokinase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78366 ! has exposure stimulus EC 2.7.1.1 (hexokinase) inhibitor
relationship: RO:0002309 CHEBI:78366 ! has exposure stimulus EC 2.7.1.1 (hexokinase) inhibitor

[Term]
id: ECTO:9002066
name: exposure to refrigerant
def: "An exposure to refrigerant." []
synonym: "refrigerant exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78433 ! has exposure stimulus refrigerant
relationship: RO:0002309 CHEBI:78433 ! has exposure stimulus refrigerant

[Term]
id: ECTO:9002067
name: exposure to EC 3.1.1.1 (carboxylesterase) inhibitor
def: "An exposure to EC 3.1.1.1 (carboxylesterase) inhibitor." []
synonym: "EC 3.1.1.1 (carboxylesterase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78444 ! has exposure stimulus EC 3.1.1.1 (carboxylesterase) inhibitor
relationship: RO:0002309 CHEBI:78444 ! has exposure stimulus EC 3.1.1.1 (carboxylesterase) inhibitor

[Term]
id: ECTO:9002068
name: exposure to protein kinase A agonist
def: "An exposure to protein kinase A agonist." []
synonym: "protein kinase A agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78547 ! has exposure stimulus protein kinase A agonist
relationship: RO:0002309 CHEBI:78547 ! has exposure stimulus protein kinase A agonist

[Term]
id: ECTO:9002069
name: exposure to adenylate cyclase agonist
def: "An exposure to adenylate cyclase agonist." []
synonym: "adenylate cyclase agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78548 ! has exposure stimulus adenylate cyclase agonist
relationship: RO:0002309 CHEBI:78548 ! has exposure stimulus adenylate cyclase agonist

[Term]
id: ECTO:9002070
name: exposure to fundamental metabolite
def: "An exposure to fundamental metabolite." []
synonym: "fundamental metabolite exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78675 ! has exposure stimulus fundamental metabolite
relationship: RO:0002309 CHEBI:78675 ! has exposure stimulus fundamental metabolite

[Term]
id: ECTO:9002071
name: exposure to plasticiser
def: "An exposure to plasticiser." []
synonym: "plasticiser exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:79056 ! has exposure stimulus plasticiser
relationship: RO:0002309 CHEBI:79056 ! has exposure stimulus plasticiser

[Term]
id: ECTO:9002072
name: exposure to phytochrome chromophore
def: "An exposure to phytochrome chromophore." []
synonym: "phytochrome chromophore exposure" EXACT []
is_a: ECTO:9001653 ! exposure to chromophore
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82632 ! has exposure stimulus phytochrome chromophore
relationship: RO:0002309 CHEBI:82632 ! has exposure stimulus phytochrome chromophore

[Term]
id: ECTO:9002073
name: exposure to EC 3.5.1.19 (nicotinamidase) inhibitor
def: "An exposure to EC 3.5.1.19 (nicotinamidase) inhibitor." []
synonym: "EC 3.5.1.19 (nicotinamidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84264 ! has exposure stimulus EC 3.5.1.19 (nicotinamidase) inhibitor
relationship: RO:0002309 CHEBI:84264 ! has exposure stimulus EC 3.5.1.19 (nicotinamidase) inhibitor

[Term]
id: ECTO:9002074
name: exposure to skin lightening agent
def: "An exposure to skin lightening agent." []
synonym: "skin lightening agent exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85046 ! has exposure stimulus skin lightening agent
relationship: RO:0002309 CHEBI:85046 ! has exposure stimulus skin lightening agent

[Term]
id: ECTO:9002075
name: exposure to EC 1.10.3.1 (catechol oxidase) inhibitor
def: "An exposure to EC 1.10.3.1 (catechol oxidase) inhibitor." []
synonym: "EC 1.10.3.1 (catechol oxidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85049 ! has exposure stimulus EC 1.10.3.1 (catechol oxidase) inhibitor
relationship: RO:0002309 CHEBI:85049 ! has exposure stimulus EC 1.10.3.1 (catechol oxidase) inhibitor

[Term]
id: ECTO:9002076
name: exposure to EC 1.10.3.2 (laccase) inhibitor
def: "An exposure to EC 1.10.3.2 (laccase) inhibitor." []
synonym: "EC 1.10.3.2 (laccase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85050 ! has exposure stimulus EC 1.10.3.2 (laccase) inhibitor
relationship: RO:0002309 CHEBI:85050 ! has exposure stimulus EC 1.10.3.2 (laccase) inhibitor

[Term]
id: ECTO:9002077
name: exposure to EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor
def: "An exposure to EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor." []
synonym: "EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85051 ! has exposure stimulus EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor
relationship: RO:0002309 CHEBI:85051 ! has exposure stimulus EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor

[Term]
id: ECTO:9002078
name: exposure to EC 1.4.3.3 (D-amino-acid oxidase) inhibitor
def: "An exposure to EC 1.4.3.3 (D-amino-acid oxidase) inhibitor." []
synonym: "EC 1.4.3.3 (D-amino-acid oxidase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85052 ! has exposure stimulus EC 1.4.3.3 (D-amino-acid oxidase) inhibitor
relationship: RO:0002309 CHEBI:85052 ! has exposure stimulus EC 1.4.3.3 (D-amino-acid oxidase) inhibitor

[Term]
id: ECTO:9002079
name: exposure to human blood serum metabolite
def: "An exposure to human blood serum metabolite." []
synonym: "human blood serum metabolite exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85234 ! has exposure stimulus human blood serum metabolite
relationship: RO:0002309 CHEBI:85234 ! has exposure stimulus human blood serum metabolite

[Term]
id: ECTO:9002080
name: exposure to antifungal drug
def: "An exposure to antifungal drug." []
synonym: "antifungal drug exposure" EXACT []
is_a: ECTO:9001711 ! exposure to antiinfective agent
is_a: ECTO:9001749 ! exposure to antifungal agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:86327 ! has exposure stimulus antifungal drug
relationship: RO:0002309 CHEBI:86327 ! has exposure stimulus antifungal drug

[Term]
id: ECTO:9002081
name: exposure to antifungal agrochemical
def: "An exposure to antifungal agrochemical." []
synonym: "antifungal agrochemical exposure" EXACT []
is_a: ECTO:9000092 ! exposure to fungicide
is_a: ECTO:9001696 ! exposure to agrochemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:86328 ! has exposure stimulus antifungal agrochemical
relationship: RO:0002309 CHEBI:86328 ! has exposure stimulus antifungal agrochemical

[Term]
id: ECTO:9002082
name: exposure to drug allergen
def: "An exposure to drug allergen." []
synonym: "drug allergen exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:0000726 ! exposure to allergen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88188 ! has exposure stimulus drug allergen
relationship: RO:0002309 CHEBI:88188 ! has exposure stimulus drug allergen

[Term]
id: ECTO:9002083
name: exposure to autophagy inhibitor
def: "An exposure to autophagy inhibitor." []
synonym: "autophagy inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88230 ! has exposure stimulus autophagy inhibitor
relationship: RO:0002309 CHEBI:88230 ! has exposure stimulus autophagy inhibitor

[Term]
id: ECTO:9002084
name: exposure to EC 6.4.1.1 (pyruvate carboxylase) inhibitor
def: "An exposure to EC 6.4.1.1 (pyruvate carboxylase) inhibitor." []
synonym: "EC 6.4.1.1 (pyruvate carboxylase) inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:90318 ! has exposure stimulus EC 6.4.1.1 (pyruvate carboxylase) inhibitor
relationship: RO:0002309 CHEBI:90318 ! has exposure stimulus EC 6.4.1.1 (pyruvate carboxylase) inhibitor

[Term]
id: ECTO:9002085
name: exposure to erythropoietin inhibitor
def: "An exposure to erythropoietin inhibitor." []
synonym: "erythropoietin inhibitor exposure" EXACT []
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:91025 ! has exposure stimulus erythropoietin inhibitor
relationship: RO:0002309 CHEBI:91025 ! has exposure stimulus erythropoietin inhibitor

[Term]
id: ECTO:9002086
name: exposure to elastin-laminin receptor agonist
def: "An exposure to elastin-laminin receptor agonist." []
synonym: "elastin-laminin receptor agonist exposure" EXACT []
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:91139 ! has exposure stimulus elastin-laminin receptor agonist
relationship: RO:0002309 CHEBI:91139 ! has exposure stimulus elastin-laminin receptor agonist

[Term]
id: ECTO:9002087
name: exposure to antifeedant
def: "An exposure to antifeedant." []
synonym: "antifeedant exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22583 ! has exposure stimulus antifeedant
relationship: RO:0002309 CHEBI:22583 ! has exposure stimulus antifeedant

[Term]
id: ECTO:9002088
name: exposure to chemosterilant
def: "An exposure to chemosterilant." []
synonym: "chemosterilant exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23092 ! has exposure stimulus chemosterilant
relationship: RO:0002309 CHEBI:23092 ! has exposure stimulus chemosterilant

[Term]
id: ECTO:9002089
name: exposure to chitin synthesis inhibitor
def: "An exposure to chitin synthesis inhibitor." []
synonym: "chitin synthesis inhibitor exposure" EXACT []
is_a: ECTO:9002093 ! exposure to insect growth regulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23100 ! has exposure stimulus chitin synthesis inhibitor
relationship: RO:0002309 CHEBI:23100 ! has exposure stimulus chitin synthesis inhibitor

[Term]
id: ECTO:9002090
name: exposure to cytochrome-b6f complex inhibitor
def: "An exposure to cytochrome-b6f complex inhibitor." []
synonym: "cytochrome-b6f complex inhibitor exposure" EXACT []
is_a: ECTO:9002097 ! exposure to photosynthetic electron-transport chain inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23529 ! has exposure stimulus cytochrome-b6f complex inhibitor
relationship: RO:0002309 CHEBI:23529 ! has exposure stimulus cytochrome-b6f complex inhibitor

[Term]
id: ECTO:9002091
name: exposure to ecdysone antagonists
def: "An exposure to ecdysone antagonists." []
synonym: "ecdysone antagonists exposure" EXACT []
is_a: ECTO:9002093 ! exposure to insect growth regulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23891 ! has exposure stimulus ecdysone antagonists
relationship: RO:0002309 CHEBI:23891 ! has exposure stimulus ecdysone antagonists

[Term]
id: ECTO:9002092
name: exposure to insect attractant
def: "An exposure to insect attractant." []
synonym: "insect attractant exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24850 ! has exposure stimulus insect attractant
relationship: RO:0002309 CHEBI:24850 ! has exposure stimulus insect attractant

[Term]
id: ECTO:9002093
name: exposure to insect growth regulator
def: "An exposure to insect growth regulator." []
synonym: "insect growth regulator exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
is_a: ECTO:9000089 ! exposure to insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24851 ! has exposure stimulus insect growth regulator
relationship: RO:0002309 CHEBI:24851 ! has exposure stimulus insect growth regulator

[Term]
id: ECTO:9002094
name: exposure to juvenile hormone antagonists
def: "An exposure to juvenile hormone antagonists." []
synonym: "juvenile hormone antagonists exposure" EXACT []
is_a: ECTO:9002093 ! exposure to insect growth regulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24941 ! has exposure stimulus juvenile hormone antagonists
relationship: RO:0002309 CHEBI:24941 ! has exposure stimulus juvenile hormone antagonists

[Term]
id: ECTO:9002095
name: exposure to juvenile hormone mimic
def: "An exposure to juvenile hormone mimic." []
synonym: "juvenile hormone mimic exposure" EXACT []
is_a: ECTO:9002093 ! exposure to insect growth regulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24942 ! has exposure stimulus juvenile hormone mimic
relationship: RO:0002309 CHEBI:24942 ! has exposure stimulus juvenile hormone mimic

[Term]
id: ECTO:9002096
name: exposure to pesticide synergist
def: "An exposure to pesticide synergist." []
synonym: "pesticide synergist exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25943 ! has exposure stimulus pesticide synergist
relationship: RO:0002309 CHEBI:25943 ! has exposure stimulus pesticide synergist

[Term]
id: ECTO:9002097
name: exposure to photosynthetic electron-transport chain inhibitor
def: "An exposure to photosynthetic electron-transport chain inhibitor." []
synonym: "photosynthetic electron-transport chain inhibitor exposure" EXACT []
is_a: ECTO:0000515 ! exposure to herbicide
is_a: ECTO:0000557 ! exposure to inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26087 ! has exposure stimulus photosynthetic electron-transport chain inhibitor
relationship: RO:0002309 CHEBI:26087 ! has exposure stimulus photosynthetic electron-transport chain inhibitor

[Term]
id: ECTO:9002098
name: exposure to photosystem-I inhibitor
def: "An exposure to photosystem-I inhibitor." []
synonym: "photosystem-I inhibitor exposure" EXACT []
is_a: ECTO:9002097 ! exposure to photosynthetic electron-transport chain inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26088 ! has exposure stimulus photosystem-I inhibitor
relationship: RO:0002309 CHEBI:26088 ! has exposure stimulus photosystem-I inhibitor

[Term]
id: ECTO:9002099
name: exposure to photosystem-II inhibitor
def: "An exposure to photosystem-II inhibitor." []
synonym: "photosystem-II inhibitor exposure" EXACT []
is_a: ECTO:9002097 ! exposure to photosynthetic electron-transport chain inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26089 ! has exposure stimulus photosystem-II inhibitor
relationship: RO:0002309 CHEBI:26089 ! has exposure stimulus photosystem-II inhibitor

[Term]
id: ECTO:9002100
name: exposure to precocenes
def: "An exposure to precocenes." []
synonym: "precocenes exposure" EXACT []
is_a: ECTO:9002094 ! exposure to juvenile hormone antagonists
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26220 ! has exposure stimulus precocenes
relationship: RO:0002309 CHEBI:26220 ! has exposure stimulus precocenes

[Term]
id: ECTO:9002101
name: exposure to pyrethroid insecticide
def: "An exposure to pyrethroid insecticide." []
synonym: "pyrethroid insecticide exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
is_a: ECTO:9000089 ! exposure to insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26413 ! has exposure stimulus pyrethroid insecticide
relationship: RO:0002309 CHEBI:26413 ! has exposure stimulus pyrethroid insecticide

[Term]
id: ECTO:9002102
name: exposure to molluscicide
def: "An exposure to molluscicide." []
synonym: "molluscicide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33904 ! has exposure stimulus molluscicide
relationship: RO:0002309 CHEBI:33904 ! has exposure stimulus molluscicide

[Term]
id: ECTO:9002103
name: exposure to acaricide drug
def: "An exposure to acaricide drug." []
synonym: "acaricide drug exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
is_a: ECTO:9001712 ! exposure to antiparasitic agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36053 ! has exposure stimulus acaricide drug
relationship: RO:0002309 CHEBI:36053 ! has exposure stimulus acaricide drug

[Term]
id: ECTO:9002104
name: exposure to ecdysone agonist
def: "An exposure to ecdysone agonist." []
synonym: "ecdysone agonist exposure" EXACT []
is_a: ECTO:9002093 ! exposure to insect growth regulator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38456 ! has exposure stimulus ecdysone agonist
relationship: RO:0002309 CHEBI:38456 ! has exposure stimulus ecdysone agonist

[Term]
id: ECTO:9002105
name: exposure to carbamate insecticide
def: "An exposure to carbamate insecticide." []
synonym: "carbamate insecticide exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
is_a: ECTO:9001784 ! exposure to EC 3.1.1.7 (acetylcholinesterase) inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38461 ! has exposure stimulus carbamate insecticide
relationship: RO:0002309 CHEBI:38461 ! has exposure stimulus carbamate insecticide

[Term]
id: ECTO:9002106
name: exposure to pyrethroid ester insecticide
def: "An exposure to pyrethroid ester insecticide." []
synonym: "pyrethroid ester insecticide exposure" EXACT []
is_a: ECTO:9002101 ! exposure to pyrethroid insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39116 ! has exposure stimulus pyrethroid ester insecticide
relationship: RO:0002309 CHEBI:39116 ! has exposure stimulus pyrethroid ester insecticide

[Term]
id: ECTO:9002107
name: exposure to antibiotic insecticide
def: "An exposure to antibiotic insecticide." []
synonym: "antibiotic insecticide exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
is_a: ECTO:9002108 ! exposure to antibiotic pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39208 ! has exposure stimulus antibiotic insecticide
relationship: RO:0002309 CHEBI:39208 ! has exposure stimulus antibiotic insecticide

[Term]
id: ECTO:9002108
name: exposure to antibiotic pesticide
def: "An exposure to antibiotic pesticide." []
synonym: "antibiotic pesticide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
is_a: ECTO:0000544 ! exposure to antimicrobial agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39215 ! has exposure stimulus antibiotic pesticide
relationship: RO:0002309 CHEBI:39215 ! has exposure stimulus antibiotic pesticide

[Term]
id: ECTO:9002109
name: exposure to antibiotic acaricide
def: "An exposure to antibiotic acaricide." []
synonym: "antibiotic acaricide exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
is_a: ECTO:9002108 ! exposure to antibiotic pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39216 ! has exposure stimulus antibiotic acaricide
relationship: RO:0002309 CHEBI:39216 ! has exposure stimulus antibiotic acaricide

[Term]
id: ECTO:9002110
name: exposure to antibiotic nematicide
def: "An exposure to antibiotic nematicide." []
synonym: "antibiotic nematicide exposure" EXACT []
is_a: ECTO:9001674 ! exposure to nematicide
is_a: ECTO:9002108 ! exposure to antibiotic pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39217 ! has exposure stimulus antibiotic nematicide
relationship: RO:0002309 CHEBI:39217 ! has exposure stimulus antibiotic nematicide

[Term]
id: ECTO:9002111
name: exposure to pyrethroid ester acaricide
def: "An exposure to pyrethroid ester acaricide." []
synonym: "pyrethroid ester acaricide exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39259 ! has exposure stimulus pyrethroid ester acaricide
relationship: RO:0002309 CHEBI:39259 ! has exposure stimulus pyrethroid ester acaricide

[Term]
id: ECTO:9002112
name: exposure to fumigant
def: "An exposure to fumigant." []
synonym: "fumigant exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39276 ! has exposure stimulus fumigant
relationship: RO:0002309 CHEBI:39276 ! has exposure stimulus fumigant

[Term]
id: ECTO:9002113
name: exposure to fumigant insecticide
def: "An exposure to fumigant insecticide." []
synonym: "fumigant insecticide exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
is_a: ECTO:9002112 ! exposure to fumigant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39277 ! has exposure stimulus fumigant insecticide
relationship: RO:0002309 CHEBI:39277 ! has exposure stimulus fumigant insecticide

[Term]
id: ECTO:9002114
name: exposure to sulfite ester acaricide
def: "An exposure to sulfite ester acaricide." []
synonym: "sulfite ester acaricide exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39301 ! has exposure stimulus sulfite ester acaricide
relationship: RO:0002309 CHEBI:39301 ! has exposure stimulus sulfite ester acaricide

[Term]
id: ECTO:9002115
name: exposure to mite growth regulator
def: "An exposure to mite growth regulator." []
synonym: "mite growth regulator exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
is_a: ECTO:9001644 ! exposure to acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39316 ! has exposure stimulus mite growth regulator
relationship: RO:0002309 CHEBI:39316 ! has exposure stimulus mite growth regulator

[Term]
id: ECTO:9002116
name: exposure to tetrazine acaricide
def: "An exposure to tetrazine acaricide." []
synonym: "tetrazine acaricide exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39318 ! has exposure stimulus tetrazine acaricide
relationship: RO:0002309 CHEBI:39318 ! has exposure stimulus tetrazine acaricide

[Term]
id: ECTO:9002117
name: exposure to pyrethroid ether insecticide
def: "An exposure to pyrethroid ether insecticide." []
synonym: "pyrethroid ether insecticide exposure" EXACT []
is_a: ECTO:9002101 ! exposure to pyrethroid insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39351 ! has exposure stimulus pyrethroid ether insecticide
relationship: RO:0002309 CHEBI:39351 ! has exposure stimulus pyrethroid ether insecticide

[Term]
id: ECTO:9002118
name: exposure to pyrethroid ether acaricide
def: "An exposure to pyrethroid ether acaricide." []
synonym: "pyrethroid ether acaricide exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39369 ! has exposure stimulus pyrethroid ether acaricide
relationship: RO:0002309 CHEBI:39369 ! has exposure stimulus pyrethroid ether acaricide

[Term]
id: ECTO:9002119
name: exposure to homopteran inhibitor of chitin biosynthesis
def: "An exposure to homopteran inhibitor of chitin biosynthesis." []
synonym: "homopteran inhibitor of chitin biosynthesis exposure" EXACT []
is_a: ECTO:9002089 ! exposure to chitin synthesis inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39378 ! has exposure stimulus homopteran inhibitor of chitin biosynthesis
relationship: RO:0002309 CHEBI:39378 ! has exposure stimulus homopteran inhibitor of chitin biosynthesis

[Term]
id: ECTO:9002120
name: exposure to lepidopteran inhibitor of chitin biosynthesis
def: "An exposure to lepidopteran inhibitor of chitin biosynthesis." []
synonym: "lepidopteran inhibitor of chitin biosynthesis exposure" EXACT []
is_a: ECTO:9002089 ! exposure to chitin synthesis inhibitor
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39379 ! has exposure stimulus lepidopteran inhibitor of chitin biosynthesis
relationship: RO:0002309 CHEBI:39379 ! has exposure stimulus lepidopteran inhibitor of chitin biosynthesis

[Term]
id: ECTO:9002121
name: exposure to dinitrophenol insecticide
def: "An exposure to dinitrophenol insecticide." []
synonym: "dinitrophenol insecticide exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39415 ! has exposure stimulus dinitrophenol insecticide
relationship: RO:0002309 CHEBI:39415 ! has exposure stimulus dinitrophenol insecticide

[Term]
id: ECTO:9002122
name: exposure to antifouling biocide
def: "An exposure to antifouling biocide." []
synonym: "antifouling biocide exposure" EXACT []
is_a: ECTO:0000530 ! exposure to pesticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:51076 ! has exposure stimulus antifouling biocide
relationship: RO:0002309 CHEBI:51076 ! has exposure stimulus antifouling biocide

[Term]
id: ECTO:9002123
name: exposure to insect sterilant
def: "An exposure to insect sterilant." []
synonym: "insect sterilant exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
is_a: ECTO:9002088 ! exposure to chemosterilant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67105 ! has exposure stimulus insect sterilant
relationship: RO:0002309 CHEBI:67105 ! has exposure stimulus insect sterilant

[Term]
id: ECTO:9002124
name: exposure to insect repellent
def: "An exposure to insect repellent." []
synonym: "insect repellent exposure" EXACT []
is_a: ECTO:9000089 ! exposure to insecticide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71692 ! has exposure stimulus insect repellent
relationship: RO:0002309 CHEBI:71692 ! has exposure stimulus insect repellent

[Term]
id: ECTO:9002125
name: exposure to scabicide
def: "An exposure to scabicide." []
synonym: "scabicide exposure" EXACT []
is_a: ECTO:9001644 ! exposure to acaricide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73333 ! has exposure stimulus scabicide
relationship: RO:0002309 CHEBI:73333 ! has exposure stimulus scabicide

[Term]
id: ECTO:9002126
name: exposure to environmental food contaminant
def: "An exposure to environmental food contaminant." []
synonym: "environmental food contaminant exposure" EXACT []
is_a: ECTO:0000931 ! exposure to environmental contaminant
is_a: ECTO:9002063 ! exposure to food component
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78299 ! has exposure stimulus environmental food contaminant
relationship: RO:0002309 CHEBI:78299 ! has exposure stimulus environmental food contaminant

[Term]
id: ECTO:9002127
name: exposure to sex hormone
def: "An exposure to sex hormone." []
synonym: "sex hormone exposure" EXACT []
is_a: ECTO:0000516 ! exposure to hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50112 ! has exposure stimulus sex hormone
relationship: RO:0002309 CHEBI:50112 ! has exposure stimulus sex hormone

[Term]
id: ECTO:9002128
name: exposure to mu-opioid receptor antagonist
def: "An exposure to mu-opioid receptor antagonist." []
synonym: "mu-opioid receptor antagonist exposure" EXACT []
is_a: ECTO:9001822 ! exposure to antagonist
is_a: ECTO:9002129 ! exposure to neurotransmitter agent
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50137 ! has exposure stimulus mu-opioid receptor antagonist
relationship: RO:0002309 CHEBI:50137 ! has exposure stimulus mu-opioid receptor antagonist

[Term]
id: ECTO:9002129
name: exposure to neurotransmitter agent
def: "An exposure to neurotransmitter agent." []
synonym: "neurotransmitter agent exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
is_a: ECTO:0000509 ! exposure to drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35942 ! has exposure stimulus neurotransmitter agent
relationship: RO:0002309 CHEBI:35942 ! has exposure stimulus neurotransmitter agent

[Term]
id: ECTO:9002130
name: exposure to food preservative
def: "An exposure to food preservative." []
synonym: "food preservative exposure" EXACT []
is_a: ECTO:9001942 ! exposure to food additive
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65255 ! has exposure stimulus food preservative
relationship: RO:0002309 CHEBI:65255 ! has exposure stimulus food preservative

[Term]
id: ECTO:9002131
name: exposure to flame retardant
def: "An exposure to flame retardant." []
synonym: "flame retardant exposure" EXACT []
is_a: ECTO:0000486 ! exposure to chemical with application
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:79314 ! has exposure stimulus flame retardant
relationship: RO:0002309 CHEBI:79314 ! has exposure stimulus flame retardant

[Term]
id: ECTO:9002132
name: exposure to methane
def: "An exposure to methane." []
synonym: "methane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16183 ! has exposure stimulus methane
relationship: RO:0002309 CHEBI:16183 ! has exposure stimulus methane

[Term]
id: ECTO:9002133
name: exposure to protein
def: "An exposure to protein." []
synonym: "protein exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36080 ! has exposure stimulus protein
relationship: RO:0002309 CHEBI:36080 ! has exposure stimulus protein

[Term]
id: ECTO:9002134
name: exposure to low-density lipoprotein
def: "An exposure to low-density lipoprotein." []
synonym: "low-density lipoprotein exposure" EXACT []
is_a: ECTO:9000303 ! exposure to lipoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39026 ! has exposure stimulus low-density lipoprotein
relationship: RO:0002309 CHEBI:39026 ! has exposure stimulus low-density lipoprotein

[Term]
id: ECTO:9002135
name: exposure to high-density lipoprotein
def: "An exposure to high-density lipoprotein." []
synonym: "high-density lipoprotein exposure" EXACT []
is_a: ECTO:9000303 ! exposure to lipoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39025 ! has exposure stimulus high-density lipoprotein
relationship: RO:0002309 CHEBI:39025 ! has exposure stimulus high-density lipoprotein

[Term]
id: ECTO:9002136
name: exposure to urea
def: "An exposure to urea." []
synonym: "urea exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16199 ! has exposure stimulus urea
relationship: RO:0002309 CHEBI:16199 ! has exposure stimulus urea

[Term]
id: ECTO:9002137
name: exposure to anilofos
def: "An exposure to Anilofos." []
synonym: "Anilofos exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81728 ! has exposure stimulus Anilofos
relationship: RO:0002309 CHEBI:81728 ! has exposure stimulus Anilofos

[Term]
id: ECTO:9002138
name: exposure to glyphosate
def: "An exposure to glyphosate." []
synonym: "glyphosate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27744 ! has exposure stimulus glyphosate
relationship: RO:0002309 CHEBI:27744 ! has exposure stimulus glyphosate

[Term]
id: ECTO:9002139
name: exposure to nitrile
def: "An exposure to nitrile." []
synonym: "nitrile exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18379 ! has exposure stimulus nitrile
relationship: RO:0002309 CHEBI:18379 ! has exposure stimulus nitrile

[Term]
id: ECTO:9002140
name: obsolete waste material exposure
is_obsolete: true
replaced_by: ECTO:7000092

[Term]
id: ECTO:9002141
name: exposure to neoprene
def: "An exposure to poly(chloroprene) polymer." []
synonym: "poly(chloroprene) polymer exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60505 ! has exposure stimulus poly(chloroprene) polymer
relationship: RO:0002309 CHEBI:60505 ! has exposure stimulus poly(chloroprene) polymer

[Term]
id: ECTO:9002142
name: exposure to epoxy
def: "An exposure to epoxy group." []
synonym: "epoxy group exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30721 ! has exposure stimulus epoxy group
relationship: RO:0002309 CHEBI:30721 ! has exposure stimulus epoxy group

[Term]
id: ECTO:9002143
name: exposure to polymides
def: "An exposure to polyimide polymer." []
synonym: "polyimide polymer exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61484 ! has exposure stimulus polyimide polymer
relationship: RO:0002309 CHEBI:61484 ! has exposure stimulus polyimide polymer

[Term]
id: ECTO:9002144
name: obsolete 1,1-Dichloroethane exposure
is_obsolete: true
replaced_by: ECTO:9000915

[Term]
id: ECTO:9002145
name: obsolete tetrachloroethene exposure
is_obsolete: true
replaced_by: ECTO:9000074

[Term]
id: ECTO:9002146
name: exposure to acids
def: "An exposure to acid." []
synonym: "acid exposure" EXACT []
is_a: ECTO:0000487 ! exposure to chemical with chemical role
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37527 ! has exposure stimulus acid
relationship: RO:0002309 CHEBI:37527 ! has exposure stimulus acid

[Term]
id: ECTO:9002147
name: exposure to chlorinated naphthalene
def: "An exposure to chlorinated naphthalene." []
synonym: "chlorinated naphthalene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:156062 ! has exposure stimulus chlorinated naphthalene
relationship: RO:0002309 CHEBI:156062 ! has exposure stimulus chlorinated naphthalene

[Term]
id: ECTO:9002148
name: exposure to polycyclic hydrocarbon
def: "An exposure to polycyclic hydrocarbon." []
synonym: "polycyclic hydrocarbon exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33666 ! has exposure stimulus polycyclic hydrocarbon
relationship: RO:0002309 CHEBI:33666 ! has exposure stimulus polycyclic hydrocarbon

[Term]
id: ECTO:9002149
name: exposure to oral contraceptive
def: "An exposure to oral contraceptive." []
synonym: "oral contraceptive exposure" EXACT []
is_a: ECTO:9001831 ! exposure to contraceptive drug
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49325 ! has exposure stimulus oral contraceptive
relationship: RO:0002309 CHEBI:49325 ! has exposure stimulus oral contraceptive

[Term]
id: ECTO:9002150
name: exposure to poly(ethylene-co-vinyl acetate)
def: "An exposure to poly(ethylene-co-vinyl acetate)." []
synonym: "poly(ethylene-co-vinyl acetate) exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:166881 ! has exposure stimulus poly(ethylene-co-vinyl acetate)
relationship: RO:0002309 CHEBI:166881 ! has exposure stimulus poly(ethylene-co-vinyl acetate)

[Term]
id: ECTO:9002151
name: exposure to niacin(b3)
def: "An exposure to nicotinic acid." []
synonym: "nicotinic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
is_a: ECTO:9002845 ! exposure to vitamin B3
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15940 ! has exposure stimulus nicotinic acid
relationship: RO:0002309 CHEBI:15940 ! has exposure stimulus nicotinic acid

[Term]
id: ECTO:9002152
name: exposure to pantothenic acid
def: "An exposure to pantothenic acid." []
synonym: "pantothenic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7916 ! has exposure stimulus pantothenic acid
relationship: RO:0002309 CHEBI:7916 ! has exposure stimulus pantothenic acid

[Term]
id: ECTO:9002153
name: exposure to isocyanates
def: "An exposure to isocyanates." []
synonym: "isocyanates exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53212 ! has exposure stimulus isocyanates
relationship: RO:0002309 CHEBI:53212 ! has exposure stimulus isocyanates

[Term]
id: ECTO:9002154
name: exposure to hematite
def: "An exposure to hematite." []
synonym: "hematite exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001456 ! exposure to ferric oxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50818 ! has exposure stimulus hematite
relationship: RO:0002309 CHEBI:50818 ! has exposure stimulus hematite

[Term]
id: ECTO:9002155
name: exposure to chlorobiphenyl
def: "An exposure to chlorobiphenyl." []
synonym: "chlorobiphenyl exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000056 ! exposure to biphenyls
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35446 ! has exposure stimulus chlorobiphenyl
relationship: RO:0002309 CHEBI:35446 ! has exposure stimulus chlorobiphenyl

[Term]
id: ECTO:9002156
name: exposure to glycol
def: "An exposure to glycol." []
synonym: "glycol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:13643 ! has exposure stimulus glycol
relationship: RO:0002309 CHEBI:13643 ! has exposure stimulus glycol

[Term]
id: ECTO:9002157
name: exposure to 1,2,5,6,9,10-hexabromocyclododecane
def: "An exposure to 1,2,5,6,9,10-hexabromocyclododecane." []
synonym: "1,2,5,6,9,10-hexabromocyclododecane exposure" EXACT []
is_a: ECTO:9002162 ! exposure to brominated flame retardant
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134063 ! has exposure stimulus 1,2,5,6,9,10-hexabromocyclododecane
relationship: RO:0002309 CHEBI:134063 ! has exposure stimulus 1,2,5,6,9,10-hexabromocyclododecane

[Term]
id: ECTO:9002158
name: exposure to warfarin
def: "An exposure to warfarin." []
synonym: "warfarin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10033 ! has exposure stimulus warfarin
relationship: RO:0002309 CHEBI:10033 ! has exposure stimulus warfarin

[Term]
id: ECTO:9002159
name: exposure to polyfluoroalkyl substance
def: "An exposure to polyfluoroalkyl substance." []
synonym: "polyfluoroalkyl substance exposure" EXACT []
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:172406 ! has exposure stimulus polyfluoroalkyl substance
relationship: RO:0002309 CHEBI:172406 ! has exposure stimulus polyfluoroalkyl substance

[Term]
id: ECTO:9002160
name: exposure to perfluoroalkyl substance
def: "An exposure to perfluoroalkyl substance." []
synonym: "perfluoroalkyl substance exposure" EXACT []
is_a: ECTO:9001620 ! exposure to perfluorinated compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:172397 ! has exposure stimulus perfluoroalkyl substance
relationship: RO:0002309 CHEBI:172397 ! has exposure stimulus perfluoroalkyl substance

[Term]
id: ECTO:9002161
name: exposure to glycol ether
def: "An exposure to glycol ether." []
synonym: "glycol ether exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:172390 ! has exposure stimulus glycol ether
relationship: RO:0002309 CHEBI:172390 ! has exposure stimulus glycol ether

[Term]
id: ECTO:9002162
name: exposure to brominated flame retardant
def: "An exposure to brominated flame retardant." []
synonym: "brominated flame retardant exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:172368 ! has exposure stimulus brominated flame retardant
relationship: RO:0002309 CHEBI:172368 ! has exposure stimulus brominated flame retardant

[Term]
id: ECTO:9002163
name: exposure to heavy metal
def: "An exposure to heavy metal." []
synonym: "heavy metal exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5631 ! has exposure stimulus heavy metal
relationship: RO:0002309 CHEBI:5631 ! has exposure stimulus heavy metal

[Term]
id: ECTO:9002164
name: exposure to desflurane
def: "An exposure to desflurane." []
synonym: "desflurane exposure" EXACT []
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4445 ! has exposure stimulus desflurane
relationship: RO:0002309 CHEBI:4445 ! has exposure stimulus desflurane

[Term]
id: ECTO:9002165
name: exposure to sevoflurane
def: "An exposure to sevoflurane." []
synonym: "sevoflurane exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9130 ! has exposure stimulus sevoflurane
relationship: RO:0002309 CHEBI:9130 ! has exposure stimulus sevoflurane

[Term]
id: ECTO:9002166
name: exposure to isoflurane
def: "An exposure to isoflurane." []
synonym: "isoflurane exposure" EXACT []
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6015 ! has exposure stimulus isoflurane
relationship: RO:0002309 CHEBI:6015 ! has exposure stimulus isoflurane

[Term]
id: ECTO:9002168
name: exposure to aldehyde
def: "An exposure to aldehyde." []
synonym: "aldehyde exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17478 ! has exposure stimulus aldehyde
relationship: RO:0002309 CHEBI:17478 ! has exposure stimulus aldehyde

[Term]
id: ECTO:9002169
name: exposure to vitamin B complex
def: "An exposure to vitamin B complex." []
synonym: "vitamin B complex exposure" EXACT []
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75782 ! has exposure stimulus vitamin B complex
relationship: RO:0002309 CHEBI:75782 ! has exposure stimulus vitamin B complex

[Term]
id: ECTO:9002170
name: exposure to phosmet
def: "An exposure to phosmet." []
synonym: "phosmet exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38786 ! has exposure stimulus phosmet
relationship: RO:0002309 CHEBI:38786 ! has exposure stimulus phosmet

[Term]
id: ECTO:9002171
name: exposure to carbon black
def: "An exposure to carbon black." []
synonym: "carbon black exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82297 ! has exposure stimulus carbon black
relationship: RO:0002309 CHEBI:82297 ! has exposure stimulus carbon black

[Term]
id: ECTO:9002172
name: exposure to 2-nitrofluorene
def: "An exposure to 2-nitrofluorene." []
synonym: "2-nitrofluorene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:1224 ! has exposure stimulus 2-nitrofluorene
relationship: RO:0002309 CHEBI:1224 ! has exposure stimulus 2-nitrofluorene

[Term]
id: ECTO:9002173
name: exposure to caesium atom
def: "An exposure to caesium atom." []
synonym: "caesium atom exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30514 ! has exposure stimulus caesium atom
relationship: RO:0002309 CHEBI:30514 ! has exposure stimulus caesium atom

[Term]
id: ECTO:9002174
name: exposure to urea herbicide
def: "An exposure to urea herbicide." []
synonym: "urea herbicide exposure" EXACT []
is_a: ECTO:0000515 ! exposure to herbicide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:188147 ! has exposure stimulus urea herbicide
relationship: RO:0002309 CHEBI:188147 ! has exposure stimulus urea herbicide

[Term]
id: ECTO:9002175
name: exposure to organophosphorus herbicide
def: "An exposure to organophosphorus herbicide." []
synonym: "organophosphorus herbicide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:188148 ! has exposure stimulus organophosphorus herbicide
relationship: RO:0002309 CHEBI:188148 ! has exposure stimulus organophosphorus herbicide

[Term]
id: ECTO:9002176
name: exposure to nitrile herbicide
def: "An exposure to nitrile herbicide." []
synonym: "nitrile herbicide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:188149 ! has exposure stimulus nitrile herbicide
relationship: RO:0002309 CHEBI:188149 ! has exposure stimulus nitrile herbicide

[Term]
id: ECTO:9002177
name: exposure to anticoagulant rodenticide
def: "An exposure to anticoagulant rodenticide." []
synonym: "anticoagulant rodenticide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:188151 ! has exposure stimulus anticoagulant rodenticide
relationship: RO:0002309 CHEBI:188151 ! has exposure stimulus anticoagulant rodenticide

[Term]
id: ECTO:9002178
name: exposure to butylparaben
def: "An exposure to Butylparaben." []
synonym: "Butylparaben exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88542 ! has exposure stimulus Butylparaben
relationship: RO:0002309 CHEBI:88542 ! has exposure stimulus Butylparaben

[Term]
id: ECTO:9002179
name: exposure to Triton X-100
def: "An exposure to Triton X-100." []
synonym: "Triton X-100 exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9750 ! has exposure stimulus Triton X-100
relationship: RO:0002309 CHEBI:9750 ! has exposure stimulus Triton X-100

[Term]
id: ECTO:9002180
name: exposure to 1-methyl-4-imidazoleacetic acid
def: "An exposure to 1-methyl-4-imidazoleacetic acid." []
synonym: "1-methyl-4-imidazoleacetic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:1606 ! has exposure stimulus 1-methyl-4-imidazoleacetic acid
relationship: RO:0002309 CHEBI:1606 ! has exposure stimulus 1-methyl-4-imidazoleacetic acid

[Term]
id: ECTO:9002181
name: exposure to 1-ethyl-beta-carboline-3-carboxylic acid
def: "An exposure to 1-ethyl-beta-carboline-3-carboxylic acid." []
synonym: "1-ethyl-beta-carboline-3-carboxylic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:225519 ! has exposure stimulus 1-ethyl-beta-carboline-3-carboxylic acid
relationship: RO:0002309 CHEBI:225519 ! has exposure stimulus 1-ethyl-beta-carboline-3-carboxylic acid

[Term]
id: ECTO:9002182
name: exposure to 1-methylcyclopropene
def: "An exposure to 1-methylcyclopropene." []
synonym: "1-methylcyclopropene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132592 ! has exposure stimulus 1-methylcyclopropene
relationship: RO:0002309 CHEBI:132592 ! has exposure stimulus 1-methylcyclopropene

[Term]
id: ECTO:9002183
name: exposure to 1-naphthaleneacetic acid
def: "An exposure to 1-naphthaleneacetic acid." []
synonym: "1-naphthaleneacetic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32918 ! has exposure stimulus 1-naphthaleneacetic acid
relationship: RO:0002309 CHEBI:32918 ! has exposure stimulus 1-naphthaleneacetic acid

[Term]
id: ECTO:9002184
name: exposure to hexadecane
def: "An exposure to hexadecane." []
synonym: "hexadecane exposure" EXACT []
is_a: ECTO:9000426 ! exposure to alkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45296 ! has exposure stimulus hexadecane
relationship: RO:0002309 CHEBI:45296 ! has exposure stimulus hexadecane

[Term]
id: ECTO:9002185
name: exposure to hexadecanoic acid
def: "An exposure to hexadecanoic acid." []
synonym: "hexadecanoic acid exposure" EXACT []
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15756 ! has exposure stimulus hexadecanoic acid
relationship: RO:0002309 CHEBI:15756 ! has exposure stimulus hexadecanoic acid

[Term]
id: ECTO:9002186
name: exposure to L-tyrosine
def: "An exposure to L-tyrosine." []
synonym: "L-tyrosine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17895 ! has exposure stimulus L-tyrosine
relationship: RO:0002309 CHEBI:17895 ! has exposure stimulus L-tyrosine

[Term]
id: ECTO:9002187
name: exposure to butane-2,3-diol
def: "An exposure to butane-2,3-diol." []
synonym: "butane-2,3-diol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9002156 ! exposure to glycol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62064 ! has exposure stimulus butane-2,3-diol
relationship: RO:0002309 CHEBI:62064 ! has exposure stimulus butane-2,3-diol

[Term]
id: ECTO:9002188
name: exposure to 2,4,6-trinitrobenzenesulfonic acid
def: "An exposure to 2,4,6-trinitrobenzenesulfonic acid." []
synonym: "2,4,6-trinitrobenzenesulfonic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53063 ! has exposure stimulus 2,4,6-trinitrobenzenesulfonic acid
relationship: RO:0002309 CHEBI:53063 ! has exposure stimulus 2,4,6-trinitrobenzenesulfonic acid

[Term]
id: ECTO:9002189
name: exposure to 2-amino-4,6-dinitrotoluene
def: "An exposure to 2-amino-4,6-dinitrotoluene." []
synonym: "2-amino-4,6-dinitrotoluene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:19452 ! has exposure stimulus 2-amino-4,6-dinitrotoluene
relationship: RO:0002309 CHEBI:19452 ! has exposure stimulus 2-amino-4,6-dinitrotoluene

[Term]
id: ECTO:9002190
name: exposure to 2-deoxy-D-glucose
def: "An exposure to 2-deoxy-D-glucose." []
synonym: "2-deoxy-D-glucose exposure" EXACT []
is_a: ECTO:9000164 ! exposure to hexose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15866 ! has exposure stimulus 2-deoxy-D-glucose
relationship: RO:0002309 CHEBI:15866 ! has exposure stimulus 2-deoxy-D-glucose

[Term]
id: ECTO:9002191
name: exposure to 2-hydroxy-3-methylbutyrate
def: "An exposure to 2-hydroxy-3-methylbutyrate." []
synonym: "2-hydroxy-3-methylbutyrate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64669 ! has exposure stimulus 2-hydroxy-3-methylbutyrate
relationship: RO:0002309 CHEBI:64669 ! has exposure stimulus 2-hydroxy-3-methylbutyrate

[Term]
id: ECTO:9002192
name: exposure to 2-hydroxyglutarate(2-)
def: "An exposure to 2-hydroxyglutarate(2-)." []
synonym: "2-hydroxyglutarate(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:11596 ! has exposure stimulus 2-hydroxyglutarate(2-)
relationship: RO:0002309 CHEBI:11596 ! has exposure stimulus 2-hydroxyglutarate(2-)

[Term]
id: ECTO:9002193
name: exposure to 2-phenylethanol
def: "An exposure to 2-phenylethanol." []
synonym: "2-phenylethanol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49000 ! has exposure stimulus 2-phenylethanol
relationship: RO:0002309 CHEBI:49000 ! has exposure stimulus 2-phenylethanol

[Term]
id: ECTO:9002194
name: exposure to L-Fucp-(1->2)-[D-Galp-(1->3)]-D-Galp
def: "An exposure to L-Fucp-(1->2)-[D-Galp-(1->3)]-D-Galp." []
synonym: "L-Fucp-(1->2)-[D-Galp-(1->3)]-D-Galp exposure" EXACT []
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:146144 ! has exposure stimulus L-Fucp-(1->2)-[D-Galp-(1->3)]-D-Galp
relationship: RO:0002309 CHEBI:146144 ! has exposure stimulus L-Fucp-(1->2)-[D-Galp-(1->3)]-D-Galp

[Term]
id: ECTO:9002195
name: exposure to 3,4-dihydroxybenzaldehyde
def: "An exposure to 3,4-dihydroxybenzaldehyde." []
synonym: "3,4-dihydroxybenzaldehyde exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50205 ! has exposure stimulus 3,4-dihydroxybenzaldehyde
relationship: RO:0002309 CHEBI:50205 ! has exposure stimulus 3,4-dihydroxybenzaldehyde

[Term]
id: ECTO:9002196
name: exposure to 3,5,6-trichloro-2-pyridinol
def: "An exposure to 3,5,6-trichloro-2-pyridinol." []
synonym: "3,5,6-trichloro-2-pyridinol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:143794 ! has exposure stimulus 3,5,6-trichloro-2-pyridinol
relationship: RO:0002309 CHEBI:143794 ! has exposure stimulus 3,5,6-trichloro-2-pyridinol

[Term]
id: ECTO:9002197
name: exposure to oxazolo[4,5-b]pyridin-2(3H)-one
def: "An exposure to oxazolo[4,5-b]pyridin-2(3H)-one." []
synonym: "oxazolo[4,5-b]pyridin-2(3H)-one exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38580 ! has exposure stimulus oxazolo[4,5-b]pyridin-2(3H)-one
relationship: RO:0002309 CHEBI:38580 ! has exposure stimulus oxazolo[4,5-b]pyridin-2(3H)-one

[Term]
id: ECTO:9002198
name: exposure to 3-isobutyl-1-methylxanthine
def: "An exposure to 3-isobutyl-1-methylxanthine." []
synonym: "3-isobutyl-1-methylxanthine exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48518 ! has exposure stimulus 3-isobutyl-1-methylxanthine
relationship: RO:0002309 CHEBI:48518 ! has exposure stimulus 3-isobutyl-1-methylxanthine

[Term]
id: ECTO:9002199
name: exposure to 3-methyladenine
def: "An exposure to 3-methyladenine." []
synonym: "3-methyladenine exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38635 ! has exposure stimulus 3-methyladenine
relationship: RO:0002309 CHEBI:38635 ! has exposure stimulus 3-methyladenine

[Term]
id: ECTO:9002200
name: exposure to 3-phenylpropionic acid
def: "An exposure to 3-phenylpropionic acid." []
synonym: "3-phenylpropionic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28631 ! has exposure stimulus 3-phenylpropionic acid
relationship: RO:0002309 CHEBI:28631 ! has exposure stimulus 3-phenylpropionic acid

[Term]
id: ECTO:9002201
name: exposure to 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-)
def: "An exposure to 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-)." []
synonym: "3',4',5-trihydroxy-3,7-dimethoxyflavone(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77710 ! has exposure stimulus 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-)
relationship: RO:0002309 CHEBI:77710 ! has exposure stimulus 3',4',5-trihydroxy-3,7-dimethoxyflavone(1-)

[Term]
id: ECTO:9002202
name: exposure to 4-guanidinobutyric acid
def: "An exposure to 4-guanidinobutyric acid." []
synonym: "4-guanidinobutyric acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:86564 ! has exposure stimulus 4-guanidinobutyric acid
relationship: RO:0002309 CHEBI:86564 ! has exposure stimulus 4-guanidinobutyric acid

[Term]
id: ECTO:9002203
name: exposure to 4-hydroxynonenal
def: "An exposure to 4-hydroxynonenal." []
synonym: "4-hydroxynonenal exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:142593 ! has exposure stimulus 4-hydroxynonenal
relationship: RO:0002309 CHEBI:142593 ! has exposure stimulus 4-hydroxynonenal

[Term]
id: ECTO:9002204
name: exposure to 4-hydroxytamoxifen
def: "An exposure to 4-hydroxytamoxifen." []
synonym: "4-hydroxytamoxifen exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:231618 ! has exposure stimulus 4-hydroxytamoxifen
relationship: RO:0002309 CHEBI:231618 ! has exposure stimulus 4-hydroxytamoxifen

[Term]
id: ECTO:9002205
name: exposure to 4-Octyl itaconate
def: "An exposure to 4-Octyl itaconate." []
synonym: "4-Octyl itaconate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233645 ! has exposure stimulus 4-Octyl itaconate
relationship: RO:0002309 CHEBI:233645 ! has exposure stimulus 4-Octyl itaconate

[Term]
id: ECTO:9002206
name: exposure to doxifluridine
def: "An exposure to doxifluridine." []
synonym: "doxifluridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31521 ! has exposure stimulus doxifluridine
relationship: RO:0002309 CHEBI:31521 ! has exposure stimulus doxifluridine

[Term]
id: ECTO:9002207
name: exposure to 5-aminolevulinic acid
def: "An exposure to 5-aminolevulinic acid." []
synonym: "5-aminolevulinic acid exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17549 ! has exposure stimulus 5-aminolevulinic acid
relationship: RO:0002309 CHEBI:17549 ! has exposure stimulus 5-aminolevulinic acid

[Term]
id: ECTO:9002208
name: exposure to 5-fluoroindole
def: "An exposure to 5-fluoroindole." []
synonym: "5-fluoroindole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72818 ! has exposure stimulus 5-fluoroindole
relationship: RO:0002309 CHEBI:72818 ! has exposure stimulus 5-fluoroindole

[Term]
id: ECTO:9002209
name: exposure to 6-ketolithocholic acid
def: "An exposure to 6-ketolithocholic acid." []
synonym: "6-ketolithocholic acid exposure" EXACT []
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:139133 ! has exposure stimulus 6-ketolithocholic acid
relationship: RO:0002309 CHEBI:139133 ! has exposure stimulus 6-ketolithocholic acid

[Term]
id: ECTO:9002210
name: exposure to mercaptopurine
def: "An exposure to mercaptopurine." []
synonym: "mercaptopurine exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50667 ! has exposure stimulus mercaptopurine
relationship: RO:0002309 CHEBI:50667 ! has exposure stimulus mercaptopurine

[Term]
id: ECTO:9002211
name: exposure to poly(styrene) nanoparticle
def: "An exposure to poly(styrene) nanoparticle." []
synonym: "poly(styrene) nanoparticle exposure" EXACT []
is_a: ECTO:9002233 ! exposure to nanoparticle
is_a: ECTO:9002563 ! exposure to polystyrene macromolecule
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134403 ! has exposure stimulus poly(styrene) nanoparticle
relationship: RO:0002309 CHEBI:134403 ! has exposure stimulus poly(styrene) nanoparticle

[Term]
id: ECTO:9002212
name: exposure to tritiated thymidine
def: "An exposure to tritiated thymidine." []
synonym: "tritiated thymidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53526 ! has exposure stimulus tritiated thymidine
relationship: RO:0002309 CHEBI:53526 ! has exposure stimulus tritiated thymidine

[Term]
id: ECTO:9002213
name: exposure to pyrabactin
def: "An exposure to pyrabactin." []
synonym: "pyrabactin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73159 ! has exposure stimulus pyrabactin
relationship: RO:0002309 CHEBI:73159 ! has exposure stimulus pyrabactin

[Term]
id: ECTO:9002214
name: exposure to abacavir
def: "An exposure to abacavir." []
synonym: "abacavir exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:421707 ! has exposure stimulus abacavir
relationship: RO:0002309 CHEBI:421707 ! has exposure stimulus abacavir

[Term]
id: ECTO:9002215
name: exposure to abiraterone acetate
def: "An exposure to abiraterone acetate." []
synonym: "abiraterone acetate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68639 ! has exposure stimulus abiraterone acetate
relationship: RO:0002309 CHEBI:68639 ! has exposure stimulus abiraterone acetate

[Term]
id: ECTO:9002216
name: exposure to acetoin
def: "An exposure to acetoin." []
synonym: "acetoin exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15688 ! has exposure stimulus acetoin
relationship: RO:0002309 CHEBI:15688 ! has exposure stimulus acetoin

[Term]
id: ECTO:9002217
name: exposure to Acoziborole
def: "An exposure to Acoziborole." []
synonym: "Acoziborole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:183111 ! has exposure stimulus Acoziborole
relationship: RO:0002309 CHEBI:183111 ! has exposure stimulus Acoziborole

[Term]
id: ECTO:9002218
name: exposure to ammonium salt
def: "An exposure to ammonium salt." []
synonym: "ammonium salt exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47704 ! has exposure stimulus ammonium salt
relationship: RO:0002309 CHEBI:47704 ! has exposure stimulus ammonium salt

[Term]
id: ECTO:9002219
name: exposure to indole-3-acetic acid
def: "An exposure to indole-3-acetic acid." []
synonym: "indole-3-acetic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16411 ! has exposure stimulus indole-3-acetic acid
relationship: RO:0002309 CHEBI:16411 ! has exposure stimulus indole-3-acetic acid

[Term]
id: ECTO:9002220
name: exposure to adenine
def: "An exposure to adenine." []
synonym: "adenine exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16708 ! has exposure stimulus adenine
relationship: RO:0002309 CHEBI:16708 ! has exposure stimulus adenine

[Term]
id: ECTO:9002221
name: exposure to adenosine
def: "An exposure to adenosine." []
synonym: "adenosine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16335 ! has exposure stimulus adenosine
relationship: RO:0002309 CHEBI:16335 ! has exposure stimulus adenosine

[Term]
id: ECTO:9002222
name: exposure to anastrozole
def: "An exposure to anastrozole." []
synonym: "anastrozole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2704 ! has exposure stimulus anastrozole
relationship: RO:0002309 CHEBI:2704 ! has exposure stimulus anastrozole

[Term]
id: ECTO:9002223
name: exposure to tamoxifen
def: "An exposure to tamoxifen." []
synonym: "tamoxifen exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000251 ! exposure to stilbenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41774 ! has exposure stimulus tamoxifen
relationship: RO:0002309 CHEBI:41774 ! has exposure stimulus tamoxifen

[Term]
id: ECTO:9002224
name: exposure to agmatine
def: "An exposure to agmatine." []
synonym: "agmatine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17431 ! has exposure stimulus agmatine
relationship: RO:0002309 CHEBI:17431 ! has exposure stimulus agmatine

[Term]
id: ECTO:9002225
name: exposure to agomelatine
def: "An exposure to agomelatine." []
synonym: "agomelatine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134990 ! has exposure stimulus agomelatine
relationship: RO:0002309 CHEBI:134990 ! has exposure stimulus agomelatine

[Term]
id: ECTO:9002226
name: exposure to allantoin
def: "An exposure to allantoin." []
synonym: "allantoin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15676 ! has exposure stimulus allantoin
relationship: RO:0002309 CHEBI:15676 ! has exposure stimulus allantoin

[Term]
id: ECTO:9002227
name: exposure to allicin
def: "An exposure to allicin." []
synonym: "allicin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28411 ! has exposure stimulus allicin
relationship: RO:0002309 CHEBI:28411 ! has exposure stimulus allicin

[Term]
id: ECTO:9002228
name: exposure to allopurinol
def: "An exposure to allopurinol." []
synonym: "allopurinol exposure" EXACT []
is_a: ECTO:9002871 ! exposure to pyrazolopyrimidine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:40279 ! has exposure stimulus allopurinol
relationship: RO:0002309 CHEBI:40279 ! has exposure stimulus allopurinol

[Term]
id: ECTO:9002229
name: exposure to alpha-amanitin
def: "An exposure to alpha-amanitin." []
synonym: "alpha-amanitin exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37415 ! has exposure stimulus alpha-amanitin
relationship: RO:0002309 CHEBI:37415 ! has exposure stimulus alpha-amanitin

[Term]
id: ECTO:9002230
name: exposure to aluminium(3+)
def: "An exposure to aluminium(3+)." []
synonym: "aluminium(3+) exposure" EXACT []
is_a: ECTO:9000181 ! exposure to aluminium cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49470 ! has exposure stimulus aluminium(3+)
relationship: RO:0002309 CHEBI:49470 ! has exposure stimulus aluminium(3+)

[Term]
id: ECTO:9002231
name: exposure to aminoglycoside antibiotic
def: "An exposure to aminoglycoside antibiotic." []
synonym: "aminoglycoside antibiotic exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22507 ! has exposure stimulus aminoglycoside antibiotic
relationship: RO:0002309 CHEBI:22507 ! has exposure stimulus aminoglycoside antibiotic

[Term]
id: ECTO:9002232
name: exposure to amoxicillin
def: "An exposure to amoxicillin." []
synonym: "amoxicillin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2676 ! has exposure stimulus amoxicillin
relationship: RO:0002309 CHEBI:2676 ! has exposure stimulus amoxicillin

[Term]
id: ECTO:9002233
name: exposure to nanoparticle
def: "An exposure to nanoparticle." []
synonym: "nanoparticle exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50803 ! has exposure stimulus nanoparticle
relationship: RO:0002309 CHEBI:50803 ! has exposure stimulus nanoparticle

[Term]
id: ECTO:9002234
name: exposure to Amphotericin B
def: "An exposure to amphotericin B." []
synonym: "amphotericin B exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2682 ! has exposure stimulus amphotericin B
relationship: RO:0002309 CHEBI:2682 ! has exposure stimulus amphotericin B

[Term]
id: ECTO:9002235
name: exposure to ampicillin
def: "An exposure to ampicillin." []
synonym: "ampicillin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28971 ! has exposure stimulus ampicillin
relationship: RO:0002309 CHEBI:28971 ! has exposure stimulus ampicillin

[Term]
id: ECTO:9002236
name: exposure to ampicillin trihydrate
def: "An exposure to ampicillin trihydrate." []
synonym: "ampicillin trihydrate exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31209 ! has exposure stimulus ampicillin trihydrate
relationship: RO:0002309 CHEBI:31209 ! has exposure stimulus ampicillin trihydrate

[Term]
id: ECTO:9002237
name: exposure to anthracycline
def: "An exposure to anthracycline." []
synonym: "anthracycline exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48120 ! has exposure stimulus anthracycline
relationship: RO:0002309 CHEBI:48120 ! has exposure stimulus anthracycline

[Term]
id: ECTO:9002238
name: exposure to escitalopram hydrobromide
def: "An exposure to escitalopram hydrobromide." []
synonym: "escitalopram hydrobromide exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77423 ! has exposure stimulus escitalopram hydrobromide
relationship: RO:0002309 CHEBI:77423 ! has exposure stimulus escitalopram hydrobromide

[Term]
id: ECTO:9002239
name: exposure to valproate semisodium
def: "An exposure to valproate semisodium." []
synonym: "valproate semisodium exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4667 ! has exposure stimulus valproate semisodium
relationship: RO:0002309 CHEBI:4667 ! has exposure stimulus valproate semisodium

[Term]
id: ECTO:9002240
name: exposure to 6-propyl-2-thiouracil
def: "An exposure to 6-propyl-2-thiouracil." []
synonym: "6-propyl-2-thiouracil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8502 ! has exposure stimulus 6-propyl-2-thiouracil
relationship: RO:0002309 CHEBI:8502 ! has exposure stimulus 6-propyl-2-thiouracil

[Term]
id: ECTO:9002241
name: exposure to benzoxaborole
def: "An exposure to benzoxaborole." []
synonym: "benzoxaborole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000173 ! exposure to boron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78240 ! has exposure stimulus benzoxaborole
relationship: RO:0002309 CHEBI:78240 ! has exposure stimulus benzoxaborole

[Term]
id: ECTO:9002242
name: exposure to arginine
def: "An exposure to arginine." []
synonym: "arginine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29016 ! has exposure stimulus arginine
relationship: RO:0002309 CHEBI:29016 ! has exposure stimulus arginine

[Term]
id: ECTO:9002243
name: exposure to aripiprazole
def: "An exposure to aripiprazole." []
synonym: "aripiprazole exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31236 ! has exposure stimulus aripiprazole
relationship: RO:0002309 CHEBI:31236 ! has exposure stimulus aripiprazole

[Term]
id: ECTO:9002244
name: exposure to aristolochic acid A
def: "An exposure to aristolochic acid A." []
synonym: "aristolochic acid A exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2825 ! has exposure stimulus aristolochic acid A
relationship: RO:0002309 CHEBI:2825 ! has exposure stimulus aristolochic acid A

[Term]
id: ECTO:9002245
name: exposure to arsenate(3-)
def: "An exposure to arsenate(3-)." []
synonym: "arsenate(3-) exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000032 ! exposure to arsenic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29125 ! has exposure stimulus arsenate(3-)
relationship: RO:0002309 CHEBI:29125 ! has exposure stimulus arsenate(3-)

[Term]
id: ECTO:9002246
name: exposure to diarsenic trioxide
def: "An exposure to diarsenic trioxide." []
synonym: "diarsenic trioxide exposure" EXACT []
is_a: ECTO:9000032 ! exposure to arsenic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30621 ! has exposure stimulus diarsenic trioxide
relationship: RO:0002309 CHEBI:30621 ! has exposure stimulus diarsenic trioxide

[Term]
id: ECTO:9002247
name: exposure to artemether
def: "An exposure to artemether." []
synonym: "artemether exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:195280 ! has exposure stimulus artemether
relationship: RO:0002309 CHEBI:195280 ! has exposure stimulus artemether

[Term]
id: ECTO:9002248
name: exposure to (+)-artemisinin
def: "An exposure to (+)-artemisinin." []
synonym: "(+)-artemisinin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:223316 ! has exposure stimulus (+)-artemisinin
relationship: RO:0002309 CHEBI:223316 ! has exposure stimulus (+)-artemisinin

[Term]
id: ECTO:9002249
name: exposure to 4-[4-(dimethylamino)styryl]-N-methylpyridinium
def: "An exposure to 4-[4-(dimethylamino)styryl]-N-methylpyridinium." []
synonym: "4-[4-(dimethylamino)styryl]-N-methylpyridinium exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72542 ! has exposure stimulus 4-[4-(dimethylamino)styryl]-N-methylpyridinium
relationship: RO:0002309 CHEBI:72542 ! has exposure stimulus 4-[4-(dimethylamino)styryl]-N-methylpyridinium

[Term]
id: ECTO:9002250
name: exposure to ceralasertib
def: "An exposure to ceralasertib." []
synonym: "ceralasertib exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:231342 ! has exposure stimulus ceralasertib
relationship: RO:0002309 CHEBI:231342 ! has exposure stimulus ceralasertib

[Term]
id: ECTO:9002251
name: exposure to auranofin
def: "An exposure to auranofin." []
synonym: "auranofin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000516 ! exposure to gold
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2922 ! has exposure stimulus auranofin
relationship: RO:0002309 CHEBI:2922 ! has exposure stimulus auranofin

[Term]
id: ECTO:9002252
name: exposure to avobenzone
def: "An exposure to avobenzone." []
synonym: "avobenzone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134751 ! has exposure stimulus avobenzone
relationship: RO:0002309 CHEBI:134751 ! has exposure stimulus avobenzone

[Term]
id: ECTO:9002253
name: exposure to axitinib
def: "An exposure to axitinib." []
synonym: "axitinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66910 ! has exposure stimulus axitinib
relationship: RO:0002309 CHEBI:66910 ! has exposure stimulus axitinib

[Term]
id: ECTO:9002254
name: exposure to 5-azacytidine
def: "An exposure to 5-azacytidine." []
synonym: "5-azacytidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2038 ! has exposure stimulus 5-azacytidine
relationship: RO:0002309 CHEBI:2038 ! has exposure stimulus 5-azacytidine

[Term]
id: ECTO:9002255
name: exposure to AZD4573
def: "An exposure to AZD4573." []
synonym: "AZD4573 exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233359 ! has exposure stimulus AZD4573
relationship: RO:0002309 CHEBI:233359 ! has exposure stimulus AZD4573

[Term]
id: ECTO:9002256
name: exposure to bafilomycin A1
def: "An exposure to bafilomycin A1." []
synonym: "bafilomycin A1 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22689 ! has exposure stimulus bafilomycin A1
relationship: RO:0002309 CHEBI:22689 ! has exposure stimulus bafilomycin A1

[Term]
id: ECTO:9002257
name: exposure to benznidazole
def: "An exposure to benznidazole." []
synonym: "benznidazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:133833 ! has exposure stimulus benznidazole
relationship: RO:0002309 CHEBI:133833 ! has exposure stimulus benznidazole

[Term]
id: ECTO:9002258
name: exposure to acibenzolar-S-methyl
def: "An exposure to acibenzolar-S-methyl." []
synonym: "acibenzolar-S-methyl exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73178 ! has exposure stimulus acibenzolar-S-methyl
relationship: RO:0002309 CHEBI:73178 ! has exposure stimulus acibenzolar-S-methyl

[Term]
id: ECTO:9002259
name: exposure to berberine
def: "An exposure to berberine." []
synonym: "berberine exposure" EXACT []
is_a: ECTO:9002675 ! exposure to berberine alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16118 ! has exposure stimulus berberine
relationship: RO:0002309 CHEBI:16118 ! has exposure stimulus berberine

[Term]
id: ECTO:9002260
name: exposure to bisphenol F
def: "An exposure to bisphenol F." []
synonym: "bisphenol F exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34575 ! has exposure stimulus bisphenol F
relationship: RO:0002309 CHEBI:34575 ! has exposure stimulus bisphenol F

[Term]
id: ECTO:9002261
name: exposure to bortezomib
def: "An exposure to bortezomib." []
synonym: "bortezomib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000470 ! exposure to L-phenylalanine derivative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52717 ! has exposure stimulus bortezomib
relationship: RO:0002309 CHEBI:52717 ! has exposure stimulus bortezomib

[Term]
id: ECTO:9002262
name: exposure to budesonide
def: "An exposure to budesonide." []
synonym: "budesonide exposure" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3207 ! has exposure stimulus budesonide
relationship: RO:0002309 CHEBI:3207 ! has exposure stimulus budesonide

[Term]
id: ECTO:9002263
name: exposure to Butylbenzyl phthalate
def: "An exposure to Butylbenzyl phthalate." []
synonym: "Butylbenzyl phthalate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34595 ! has exposure stimulus Butylbenzyl phthalate
relationship: RO:0002309 CHEBI:34595 ! has exposure stimulus Butylbenzyl phthalate

[Term]
id: ECTO:9002264
name: exposure to cabozantinib
def: "An exposure to cabozantinib." []
synonym: "cabozantinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72317 ! has exposure stimulus cabozantinib
relationship: RO:0002309 CHEBI:72317 ! has exposure stimulus cabozantinib

[Term]
id: ECTO:9002265
name: exposure to cadaverine
def: "An exposure to cadaverine." []
synonym: "cadaverine exposure" EXACT []
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18127 ! has exposure stimulus cadaverine
relationship: RO:0002309 CHEBI:18127 ! has exposure stimulus cadaverine

[Term]
id: ECTO:9002266
name: exposure to cadmium atom
def: "An exposure to cadmium atom." []
synonym: "cadmium atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22977 ! has exposure stimulus cadmium atom
relationship: RO:0002309 CHEBI:22977 ! has exposure stimulus cadmium atom

[Term]
id: ECTO:9002267
name: exposure to cadmium(2+)
def: "An exposure to cadmium(2+)." []
synonym: "cadmium(2+) exposure" EXACT []
is_a: ECTO:9000286 ! exposure to cadmium cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48775 ! has exposure stimulus cadmium(2+)
relationship: RO:0002309 CHEBI:48775 ! has exposure stimulus cadmium(2+)

[Term]
id: ECTO:9002268
name: exposure to cadmium dichloride
def: "An exposure to cadmium dichloride." []
synonym: "cadmium dichloride exposure" EXACT []
is_a: ECTO:0001566 ! exposure to cadmium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35456 ! has exposure stimulus cadmium dichloride
relationship: RO:0002309 CHEBI:35456 ! has exposure stimulus cadmium dichloride

[Term]
id: ECTO:9002269
name: exposure to caffeic acid
def: "An exposure to caffeic acid." []
synonym: "caffeic acid exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36281 ! has exposure stimulus caffeic acid
relationship: RO:0002309 CHEBI:36281 ! has exposure stimulus caffeic acid

[Term]
id: ECTO:9002270
name: exposure to capecitabine
def: "An exposure to capecitabine." []
synonym: "capecitabine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31348 ! has exposure stimulus capecitabine
relationship: RO:0002309 CHEBI:31348 ! has exposure stimulus capecitabine

[Term]
id: ECTO:9002271
name: exposure to polybutylene adipate terephthalate
def: "An exposure to polybutylene adipate terephthalate." []
synonym: "polybutylene adipate terephthalate exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:194148 ! has exposure stimulus polybutylene adipate terephthalate
relationship: RO:0002309 CHEBI:194148 ! has exposure stimulus polybutylene adipate terephthalate

[Term]
id: ECTO:9002272
name: exposure to caspofungin acetate
def: "An exposure to caspofungin acetate." []
synonym: "caspofungin acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59900 ! has exposure stimulus caspofungin acetate
relationship: RO:0002309 CHEBI:59900 ! has exposure stimulus caspofungin acetate

[Term]
id: ECTO:9002273
name: exposure to palbociclib
def: "An exposure to palbociclib." []
synonym: "palbociclib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85993 ! has exposure stimulus palbociclib
relationship: RO:0002309 CHEBI:85993 ! has exposure stimulus palbociclib

[Term]
id: ECTO:9002274
name: exposure to cadmium selenide nanoparticle
def: "An exposure to cadmium selenide nanoparticle." []
synonym: "cadmium selenide nanoparticle exposure" EXACT []
is_a: ECTO:0001566 ! exposure to cadmium
is_a: ECTO:9002233 ! exposure to nanoparticle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50835 ! has exposure stimulus cadmium selenide nanoparticle
relationship: RO:0002309 CHEBI:50835 ! has exposure stimulus cadmium selenide nanoparticle

[Term]
id: ECTO:9002275
name: exposure to cefotaxime(1-)
def: "An exposure to cefotaxime(1-)." []
synonym: "cefotaxime(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53670 ! has exposure stimulus cefotaxime(1-)
relationship: RO:0002309 CHEBI:53670 ! has exposure stimulus cefotaxime(1-)

[Term]
id: ECTO:9002276
name: exposure to ceftazidime
def: "An exposure to ceftazidime." []
synonym: "ceftazidime exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3508 ! has exposure stimulus ceftazidime
relationship: RO:0002309 CHEBI:3508 ! has exposure stimulus ceftazidime

[Term]
id: ECTO:9002277
name: exposure to celastrol
def: "An exposure to celastrol." []
synonym: "celastrol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63959 ! has exposure stimulus celastrol
relationship: RO:0002309 CHEBI:63959 ! has exposure stimulus celastrol

[Term]
id: ECTO:9002278
name: exposure to celecoxib
def: "An exposure to celecoxib." []
synonym: "celecoxib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41423 ! has exposure stimulus celecoxib
relationship: RO:0002309 CHEBI:41423 ! has exposure stimulus celecoxib

[Term]
id: ECTO:9002279
name: exposure to cellobiose
def: "An exposure to cellobiose." []
synonym: "cellobiose exposure" EXACT []
is_a: ECTO:9000240 ! exposure to disaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17057 ! has exposure stimulus cellobiose
relationship: RO:0002309 CHEBI:17057 ! has exposure stimulus cellobiose

[Term]
id: ECTO:9002280
name: exposure to cerivastatin(1-)
def: "An exposure to cerivastatin(1-)." []
synonym: "cerivastatin(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:406059 ! has exposure stimulus cerivastatin(1-)
relationship: RO:0002309 CHEBI:406059 ! has exposure stimulus cerivastatin(1-)

[Term]
id: ECTO:9002281
name: exposure to caesium(1+)
def: "An exposure to caesium(1+)." []
synonym: "caesium(1+) exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9000184 ! exposure to caesium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49547 ! has exposure stimulus caesium(1+)
relationship: RO:0002309 CHEBI:49547 ! has exposure stimulus caesium(1+)

[Term]
id: ECTO:9002282
name: exposure to chidamide
def: "An exposure to chidamide." []
synonym: "chidamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:135918 ! has exposure stimulus chidamide
relationship: RO:0002309 CHEBI:135918 ! has exposure stimulus chidamide

[Term]
id: ECTO:9002283
name: exposure to CHIR-090
def: "An exposure to CHIR-090." []
synonym: "CHIR-090 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:134107 ! has exposure stimulus CHIR-090
relationship: RO:0002309 CHEBI:134107 ! has exposure stimulus CHIR-090

[Term]
id: ECTO:9002284
name: exposure to chlorambucil
def: "An exposure to chlorambucil." []
synonym: "chlorambucil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28830 ! has exposure stimulus chlorambucil
relationship: RO:0002309 CHEBI:28830 ! has exposure stimulus chlorambucil

[Term]
id: ECTO:9002285
name: exposure to Chloramine
def: "An exposure to Chloramine." []
synonym: "Chloramine exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82415 ! has exposure stimulus Chloramine
relationship: RO:0002309 CHEBI:82415 ! has exposure stimulus Chloramine

[Term]
id: ECTO:9002286
name: exposure to chlordecone alcohol
def: "An exposure to chlordecone alcohol." []
synonym: "chlordecone alcohol exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17184 ! has exposure stimulus chlordecone alcohol
relationship: RO:0002309 CHEBI:17184 ! has exposure stimulus chlordecone alcohol

[Term]
id: ECTO:9002287
name: exposure to chlorthalidone
def: "An exposure to chlorthalidone." []
synonym: "chlorthalidone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3654 ! has exposure stimulus chlorthalidone
relationship: RO:0002309 CHEBI:3654 ! has exposure stimulus chlorthalidone

[Term]
id: ECTO:9002288
name: exposure to ionic liquid
def: "An exposure to ionic liquid." []
synonym: "ionic liquid exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63895 ! has exposure stimulus ionic liquid
relationship: RO:0002309 CHEBI:63895 ! has exposure stimulus ionic liquid

[Term]
id: ECTO:9002289
name: exposure to chromium(3+)
def: "An exposure to chromium(3+)." []
synonym: "chromium(3+) exposure" EXACT []
is_a: ECTO:9000037 ! exposure to chromium
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49544 ! has exposure stimulus chromium(3+)
relationship: RO:0002309 CHEBI:49544 ! has exposure stimulus chromium(3+)

[Term]
id: ECTO:9002290
name: exposure to D-alanine
def: "An exposure to D-alanine." []
synonym: "D-alanine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15570 ! has exposure stimulus D-alanine
relationship: RO:0002309 CHEBI:15570 ! has exposure stimulus D-alanine

[Term]
id: ECTO:9002291
name: exposure to CHZ868
def: "An exposure to CHZ868." []
synonym: "CHZ868 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:90828 ! has exposure stimulus CHZ868
relationship: RO:0002309 CHEBI:90828 ! has exposure stimulus CHZ868

[Term]
id: ECTO:9002292
name: exposure to essential oil
def: "An exposure to essential oil." []
synonym: "essential oil exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83630 ! has exposure stimulus essential oil
relationship: RO:0002309 CHEBI:83630 ! has exposure stimulus essential oil

[Term]
id: ECTO:9002293
name: exposure to citrate anion
def: "An exposure to citrate anion." []
synonym: "citrate anion exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:133748 ! has exposure stimulus citrate anion
relationship: RO:0002309 CHEBI:133748 ! has exposure stimulus citrate anion

[Term]
id: ECTO:9002294
name: exposure to citric acid
def: "An exposure to citric acid." []
synonym: "citric acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30769 ! has exposure stimulus citric acid
relationship: RO:0002309 CHEBI:30769 ! has exposure stimulus citric acid

[Term]
id: ECTO:9002295
name: exposure to cladribine
def: "An exposure to cladribine." []
synonym: "cladribine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:567361 ! has exposure stimulus cladribine
relationship: RO:0002309 CHEBI:567361 ! has exposure stimulus cladribine

[Term]
id: ECTO:9002296
name: exposure to clenbuterol
def: "An exposure to clenbuterol." []
synonym: "clenbuterol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:174690 ! has exposure stimulus clenbuterol
relationship: RO:0002309 CHEBI:174690 ! has exposure stimulus clenbuterol

[Term]
id: ECTO:9002297
name: exposure to clonidine
def: "An exposure to clonidine." []
synonym: "clonidine exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46631 ! has exposure stimulus clonidine
relationship: RO:0002309 CHEBI:46631 ! has exposure stimulus clonidine

[Term]
id: ECTO:9002298
name: exposure to cobalt dichloride
def: "An exposure to cobalt dichloride." []
synonym: "cobalt dichloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9000943 ! exposure to cobalt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35696 ! has exposure stimulus cobalt dichloride
relationship: RO:0002309 CHEBI:35696 ! has exposure stimulus cobalt dichloride

[Term]
id: ECTO:9002299
name: exposure to coenzyme A
def: "An exposure to coenzyme A." []
synonym: "coenzyme A exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15346 ! has exposure stimulus coenzyme A
relationship: RO:0002309 CHEBI:15346 ! has exposure stimulus coenzyme A

[Term]
id: ECTO:9002300
name: exposure to colchicine
def: "An exposure to colchicine." []
synonym: "colchicine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23359 ! has exposure stimulus colchicine
relationship: RO:0002309 CHEBI:23359 ! has exposure stimulus colchicine

[Term]
id: ECTO:9002301
name: exposure to colibactin
def: "An exposure to colibactin." []
synonym: "colibactin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:156303 ! has exposure stimulus colibactin
relationship: RO:0002309 CHEBI:156303 ! has exposure stimulus colibactin

[Term]
id: ECTO:9002302
name: exposure to colistin
def: "An exposure to colistin." []
synonym: "colistin exposure" EXACT []
is_a: ECTO:9002561 ! exposure to polymyxin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37943 ! has exposure stimulus colistin
relationship: RO:0002309 CHEBI:37943 ! has exposure stimulus colistin

[Term]
id: ECTO:9002303
name: exposure to rosiglitazone
def: "An exposure to rosiglitazone." []
synonym: "rosiglitazone exposure" EXACT []
is_a: ECTO:9000013 ! exposure to thiazolidinediones
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50122 ! has exposure stimulus rosiglitazone
relationship: RO:0002309 CHEBI:50122 ! has exposure stimulus rosiglitazone

[Term]
id: ECTO:9002304
name: exposure to GW405833
def: "An exposure to GW405833." []
synonym: "GW405833 exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:92184 ! has exposure stimulus GW405833
relationship: RO:0002309 CHEBI:92184 ! has exposure stimulus GW405833

[Term]
id: ECTO:9002305
name: exposure to Urolithin B
def: "An exposure to Urolithin B." []
synonym: "Urolithin B exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:166606 ! has exposure stimulus Urolithin B
relationship: RO:0002309 CHEBI:166606 ! has exposure stimulus Urolithin B

[Term]
id: ECTO:9002306
name: exposure to puerarin
def: "An exposure to puerarin." []
synonym: "puerarin exposure" EXACT []
is_a: ECTO:9000231 ! exposure to hydroxyisoflavone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8633 ! has exposure stimulus puerarin
relationship: RO:0002309 CHEBI:8633 ! has exposure stimulus puerarin

[Term]
id: ECTO:9002307
name: exposure to coniferyl aldehyde
def: "An exposure to coniferyl aldehyde." []
synonym: "coniferyl aldehyde exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9001353 ! exposure to phenols
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16547 ! has exposure stimulus coniferyl aldehyde
relationship: RO:0002309 CHEBI:16547 ! has exposure stimulus coniferyl aldehyde

[Term]
id: ECTO:9002308
name: exposure to trametinib
def: "An exposure to trametinib." []
synonym: "trametinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75998 ! has exposure stimulus trametinib
relationship: RO:0002309 CHEBI:75998 ! has exposure stimulus trametinib

[Term]
id: ECTO:9002309
name: exposure to copper atom
def: "An exposure to copper atom." []
synonym: "copper atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28694 ! has exposure stimulus copper atom
relationship: RO:0002309 CHEBI:28694 ! has exposure stimulus copper atom

[Term]
id: ECTO:9002310
name: exposure to copper(II) sulfate
def: "An exposure to copper(II) sulfate." []
synonym: "copper(II) sulfate exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23414 ! has exposure stimulus copper(II) sulfate
relationship: RO:0002309 CHEBI:23414 ! has exposure stimulus copper(II) sulfate

[Term]
id: ECTO:9002311
name: exposure to coumaric acid
def: "An exposure to coumaric acid." []
synonym: "coumaric acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23401 ! has exposure stimulus coumaric acid
relationship: RO:0002309 CHEBI:23401 ! has exposure stimulus coumaric acid

[Term]
id: ECTO:9002312
name: exposure to crizotinib
def: "An exposure to crizotinib." []
synonym: "crizotinib exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64310 ! has exposure stimulus crizotinib
relationship: RO:0002309 CHEBI:64310 ! has exposure stimulus crizotinib

[Term]
id: ECTO:9002313
name: exposure to copper(II) chloride
def: "An exposure to copper(II) chloride." []
synonym: "copper(II) chloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9000944 ! exposure to copper
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49553 ! has exposure stimulus copper(II) chloride
relationship: RO:0002309 CHEBI:49553 ! has exposure stimulus copper(II) chloride

[Term]
id: ECTO:9002314
name: exposure to cyclosporin A
def: "An exposure to cyclosporin A." []
synonym: "cyclosporin A exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4031 ! has exposure stimulus cyclosporin A
relationship: RO:0002309 CHEBI:4031 ! has exposure stimulus cyclosporin A

[Term]
id: ECTO:9002315
name: exposure to cypermethrin
def: "An exposure to cypermethrin." []
synonym: "cypermethrin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4042 ! has exposure stimulus cypermethrin
relationship: RO:0002309 CHEBI:4042 ! has exposure stimulus cypermethrin

[Term]
id: ECTO:9002316
name: exposure to cyromazine
def: "An exposure to cyromazine." []
synonym: "cyromazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30260 ! has exposure stimulus cyromazine
relationship: RO:0002309 CHEBI:30260 ! has exposure stimulus cyromazine

[Term]
id: ECTO:9002317
name: exposure to cysteamine
def: "An exposure to cysteamine." []
synonym: "cysteamine exposure" EXACT []
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17141 ! has exposure stimulus cysteamine
relationship: RO:0002309 CHEBI:17141 ! has exposure stimulus cysteamine

[Term]
id: ECTO:9002318
name: exposure to cysteamine bitartrate
def: "An exposure to cysteamine bitartrate." []
synonym: "cysteamine bitartrate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50386 ! has exposure stimulus cysteamine bitartrate
relationship: RO:0002309 CHEBI:50386 ! has exposure stimulus cysteamine bitartrate

[Term]
id: ECTO:9002319
name: exposure to 9-(beta-D-glucosyl)-trans-zeatin
def: "An exposure to 9-(beta-D-glucosyl)-trans-zeatin." []
synonym: "9-(beta-D-glucosyl)-trans-zeatin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:133210 ! has exposure stimulus 9-(beta-D-glucosyl)-trans-zeatin
relationship: RO:0002309 CHEBI:133210 ! has exposure stimulus 9-(beta-D-glucosyl)-trans-zeatin

[Term]
id: ECTO:9002320
name: exposure to D-galactose
def: "An exposure to D-galactose." []
synonym: "D-galactose exposure" EXACT []
is_a: ECTO:9002385 ! exposure to galactose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:12936 ! has exposure stimulus D-galactose
relationship: RO:0002309 CHEBI:12936 ! has exposure stimulus D-galactose

[Term]
id: ECTO:9002321
name: exposure to dabigatran
def: "An exposure to dabigatran." []
synonym: "dabigatran exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70752 ! has exposure stimulus dabigatran
relationship: RO:0002309 CHEBI:70752 ! has exposure stimulus dabigatran

[Term]
id: ECTO:9002322
name: exposure to dabrafenib
def: "An exposure to dabrafenib." []
synonym: "dabrafenib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75045 ! has exposure stimulus dabrafenib
relationship: RO:0002309 CHEBI:75045 ! has exposure stimulus dabrafenib

[Term]
id: ECTO:9002324
name: exposure to daptomycin
def: "An exposure to daptomycin." []
synonym: "daptomycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:600103 ! has exposure stimulus daptomycin
relationship: RO:0002309 CHEBI:600103 ! has exposure stimulus daptomycin

[Term]
id: ECTO:9002325
name: exposure to dasatinib (anhydrous)
def: "An exposure to dasatinib (anhydrous)." []
synonym: "dasatinib (anhydrous) exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49375 ! has exposure stimulus dasatinib (anhydrous)
relationship: RO:0002309 CHEBI:49375 ! has exposure stimulus dasatinib (anhydrous)

[Term]
id: ECTO:9002326
name: exposure to daunorubicin
def: "An exposure to daunorubicin." []
synonym: "daunorubicin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001246 ! exposure to quinone
is_a: ECTO:9002231 ! exposure to aminoglycoside antibiotic
is_a: ECTO:9002237 ! exposure to anthracycline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41977 ! has exposure stimulus daunorubicin
relationship: RO:0002309 CHEBI:41977 ! has exposure stimulus daunorubicin

[Term]
id: ECTO:9002327
name: exposure to dehydroascorbic acid
def: "An exposure to dehydroascorbic acid." []
synonym: "dehydroascorbic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17242 ! has exposure stimulus dehydroascorbic acid
relationship: RO:0002309 CHEBI:17242 ! has exposure stimulus dehydroascorbic acid

[Term]
id: ECTO:9002328
name: exposure to deoxyartemisinin
def: "An exposure to deoxyartemisinin." []
synonym: "deoxyartemisinin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:234135 ! has exposure stimulus deoxyartemisinin
relationship: RO:0002309 CHEBI:234135 ! has exposure stimulus deoxyartemisinin

[Term]
id: ECTO:9002329
name: exposure to deoxycholate
def: "An exposure to deoxycholate." []
synonym: "deoxycholate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23614 ! has exposure stimulus deoxycholate
relationship: RO:0002309 CHEBI:23614 ! has exposure stimulus deoxycholate

[Term]
id: ECTO:9002330
name: exposure to deoxynivalenol
def: "An exposure to deoxynivalenol." []
synonym: "deoxynivalenol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10022 ! has exposure stimulus deoxynivalenol
relationship: RO:0002309 CHEBI:10022 ! has exposure stimulus deoxynivalenol

[Term]
id: ECTO:9002331
name: exposure to deuterium atom
def: "An exposure to deuterium atom." []
synonym: "deuterium atom exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29237 ! has exposure stimulus deuterium atom
relationship: RO:0002309 CHEBI:29237 ! has exposure stimulus deuterium atom

[Term]
id: ECTO:9002332
name: exposure to dexmedetomidine
def: "An exposure to dexmedetomidine." []
synonym: "dexmedetomidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4466 ! has exposure stimulus dexmedetomidine
relationship: RO:0002309 CHEBI:4466 ! has exposure stimulus dexmedetomidine

[Term]
id: ECTO:9002333
name: exposure to dextran sulfate sodium
def: "An exposure to dextran sulfate sodium." []
synonym: "dextran sulfate sodium exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:191875 ! has exposure stimulus dextran sulfate sodium
relationship: RO:0002309 CHEBI:191875 ! has exposure stimulus dextran sulfate sodium

[Term]
id: ECTO:9002334
name: exposure to 17beta-hydroxy-5alpha-androstan-3-one
def: "An exposure to 17beta-hydroxy-5alpha-androstan-3-one." []
synonym: "17beta-hydroxy-5alpha-androstan-3-one exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16330 ! has exposure stimulus 17beta-hydroxy-5alpha-androstan-3-one
relationship: RO:0002309 CHEBI:16330 ! has exposure stimulus 17beta-hydroxy-5alpha-androstan-3-one

[Term]
id: ECTO:9002335
name: exposure to diallyl disulfide
def: "An exposure to diallyl disulfide." []
synonym: "diallyl disulfide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4488 ! has exposure stimulus diallyl disulfide
relationship: RO:0002309 CHEBI:4488 ! has exposure stimulus diallyl disulfide

[Term]
id: ECTO:9002336
name: exposure to Diallyltetrasulfane
def: "An exposure to Diallyltetrasulfane." []
synonym: "Diallyltetrasulfane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:177763 ! has exposure stimulus Diallyltetrasulfane
relationship: RO:0002309 CHEBI:177763 ! has exposure stimulus Diallyltetrasulfane

[Term]
id: ECTO:9002337
name: exposure to glucosinolate
def: "An exposure to glucosinolate." []
synonym: "glucosinolate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24279 ! has exposure stimulus glucosinolate
relationship: RO:0002309 CHEBI:24279 ! has exposure stimulus glucosinolate

[Term]
id: ECTO:9002338
name: exposure to nucleotide
def: "An exposure to nucleotide." []
synonym: "nucleotide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36976 ! has exposure stimulus nucleotide
relationship: RO:0002309 CHEBI:36976 ! has exposure stimulus nucleotide

[Term]
id: ECTO:9002339
name: exposure to soyasaponin III(1-)
def: "An exposure to soyasaponin III(1-)." []
synonym: "soyasaponin III(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62911 ! has exposure stimulus soyasaponin III(1-)
relationship: RO:0002309 CHEBI:62911 ! has exposure stimulus soyasaponin III(1-)

[Term]
id: ECTO:9002340
name: exposure to dihydroartemisinin
def: "An exposure to dihydroartemisinin." []
synonym: "dihydroartemisinin exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:207229 ! has exposure stimulus dihydroartemisinin
relationship: RO:0002309 CHEBI:207229 ! has exposure stimulus dihydroartemisinin

[Term]
id: ECTO:9002341
name: exposure to Dinoterb
def: "An exposure to Dinoterb." []
synonym: "Dinoterb exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81883 ! has exposure stimulus Dinoterb
relationship: RO:0002309 CHEBI:81883 ! has exposure stimulus Dinoterb

[Term]
id: ECTO:9002342
name: exposure to silver(1+)
def: "An exposure to silver(1+)." []
synonym: "silver(1+) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000193 ! exposure to silver cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49468 ! has exposure stimulus silver(1+)
relationship: RO:0002309 CHEBI:49468 ! has exposure stimulus silver(1+)

[Term]
id: ECTO:9002343
name: exposure to all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
def: "An exposure to all-cis-docosa-4,7,10,13,16,19-hexaenoic acid." []
synonym: "all-cis-docosa-4,7,10,13,16,19-hexaenoic acid exposure" EXACT []
is_a: ECTO:9002766 ! exposure to omega-3 fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28125 ! has exposure stimulus all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
relationship: RO:0002309 CHEBI:28125 ! has exposure stimulus all-cis-docosa-4,7,10,13,16,19-hexaenoic acid

[Term]
id: ECTO:9002344
name: exposure to doxycycline
def: "An exposure to doxycycline." []
synonym: "doxycycline exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50845 ! has exposure stimulus doxycycline
relationship: RO:0002309 CHEBI:50845 ! has exposure stimulus doxycycline

[Term]
id: ECTO:9002345
name: exposure to DTAGv-1
def: "An exposure to DTAGv-1." []
synonym: "DTAGv-1 exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233323 ! has exposure stimulus DTAGv-1
relationship: RO:0002309 CHEBI:233323 ! has exposure stimulus DTAGv-1

[Term]
id: ECTO:9002346
name: exposure to duloxetine
def: "An exposure to duloxetine." []
synonym: "duloxetine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36796 ! has exposure stimulus duloxetine
relationship: RO:0002309 CHEBI:36796 ! has exposure stimulus duloxetine

[Term]
id: ECTO:9002347
name: exposure to EDTA monocalcium diisodium salt
def: "An exposure to EDTA monocalcium diisodium salt." []
synonym: "EDTA monocalcium diisodium salt exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4757 ! has exposure stimulus EDTA monocalcium diisodium salt
relationship: RO:0002309 CHEBI:4757 ! has exposure stimulus EDTA monocalcium diisodium salt

[Term]
id: ECTO:9002348
name: exposure to eflornithine hydrochloride monohydrate
def: "An exposure to eflornithine hydrochloride monohydrate." []
synonym: "eflornithine hydrochloride monohydrate exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4762 ! has exposure stimulus eflornithine hydrochloride monohydrate
relationship: RO:0002309 CHEBI:4762 ! has exposure stimulus eflornithine hydrochloride monohydrate

[Term]
id: ECTO:9002349
name: exposure to eflornithine
def: "An exposure to eflornithine." []
synonym: "eflornithine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:41948 ! has exposure stimulus eflornithine
relationship: RO:0002309 CHEBI:41948 ! has exposure stimulus eflornithine

[Term]
id: ECTO:9002350
name: exposure to erlotinib
def: "An exposure to erlotinib." []
synonym: "erlotinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:114785 ! has exposure stimulus erlotinib
relationship: RO:0002309 CHEBI:114785 ! has exposure stimulus erlotinib

[Term]
id: ECTO:9002351
name: exposure to all-cis-5,8,11,14,17-icosapentaenoic acid
def: "An exposure to all-cis-5,8,11,14,17-icosapentaenoic acid." []
synonym: "all-cis-5,8,11,14,17-icosapentaenoic acid exposure" EXACT []
is_a: ECTO:9002766 ! exposure to omega-3 fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28364 ! has exposure stimulus all-cis-5,8,11,14,17-icosapentaenoic acid
relationship: RO:0002309 CHEBI:28364 ! has exposure stimulus all-cis-5,8,11,14,17-icosapentaenoic acid

[Term]
id: ECTO:9002352
name: exposure to succinate
def: "An exposure to succinate." []
synonym: "succinate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26806 ! has exposure stimulus succinate
relationship: RO:0002309 CHEBI:26806 ! has exposure stimulus succinate

[Term]
id: ECTO:9002353
name: exposure to empagliflozin
def: "An exposure to empagliflozin." []
synonym: "empagliflozin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82720 ! has exposure stimulus empagliflozin
relationship: RO:0002309 CHEBI:82720 ! has exposure stimulus empagliflozin

[Term]
id: ECTO:9002354
name: exposure to entecavir (anhydrous)
def: "An exposure to entecavir (anhydrous)." []
synonym: "entecavir (anhydrous) exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:473990 ! has exposure stimulus entecavir (anhydrous)
relationship: RO:0002309 CHEBI:473990 ! has exposure stimulus entecavir (anhydrous)

[Term]
id: ECTO:9002355
name: exposure to arsenic atom
def: "An exposure to arsenic atom." []
synonym: "arsenic atom exposure" EXACT []
is_a: ECTO:9001631 ! exposure to metalloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27563 ! has exposure stimulus arsenic atom
relationship: RO:0002309 CHEBI:27563 ! has exposure stimulus arsenic atom

[Term]
id: ECTO:9002356
name: exposure to epirubicin hydrochloride
def: "An exposure to epirubicin hydrochloride." []
synonym: "epirubicin hydrochloride exposure" EXACT []
is_a: ECTO:9002237 ! exposure to anthracycline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:232543 ! has exposure stimulus epirubicin hydrochloride
relationship: RO:0002309 CHEBI:232543 ! has exposure stimulus epirubicin hydrochloride

[Term]
id: ECTO:9002357
name: exposure to eriodictyol
def: "An exposure to eriodictyol." []
synonym: "eriodictyol exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28412 ! has exposure stimulus eriodictyol
relationship: RO:0002309 CHEBI:28412 ! has exposure stimulus eriodictyol

[Term]
id: ECTO:9002358
name: exposure to erlotinib hydrochloride
def: "An exposure to erlotinib hydrochloride." []
synonym: "erlotinib hydrochloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53509 ! has exposure stimulus erlotinib hydrochloride
relationship: RO:0002309 CHEBI:53509 ! has exposure stimulus erlotinib hydrochloride

[Term]
id: ECTO:9002359
name: exposure to etomidate
def: "An exposure to etomidate." []
synonym: "etomidate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4910 ! has exposure stimulus etomidate
relationship: RO:0002309 CHEBI:4910 ! has exposure stimulus etomidate

[Term]
id: ECTO:9002360
name: exposure to etomoxir
def: "An exposure to etomoxir." []
synonym: "etomoxir exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:232547 ! has exposure stimulus etomoxir
relationship: RO:0002309 CHEBI:232547 ! has exposure stimulus etomoxir

[Term]
id: ECTO:9002361
name: exposure to beta-Glcp-(1->6)-\{beta-Glcp-(1->6)-\{[beta-Glcp-(1->3)]5\}-[beta-Glcp-(1->3)]5\}-[beta-Glcp-(1->3)]4-beta-Glcp
def: "An exposure to beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp." []
synonym: "beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62319 ! has exposure stimulus beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp
relationship: RO:0002309 CHEBI:62319 ! has exposure stimulus beta-Glcp-(1->6)-{beta-Glcp-(1->6)-{[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]5}-[beta-Glcp-(1->3)]4-beta-Glcp

[Term]
id: ECTO:9002362
name: exposure to L-leucine zwitterion
def: "An exposure to L-leucine zwitterion." []
synonym: "L-leucine zwitterion exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:57427 ! has exposure stimulus L-leucine zwitterion
relationship: RO:0002309 CHEBI:57427 ! has exposure stimulus L-leucine zwitterion

[Term]
id: ECTO:9002363
name: exposure to (-)-methyl jasmonate
def: "An exposure to (-)-methyl jasmonate." []
synonym: "(-)-methyl jasmonate exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000308 ! exposure to fatty acid
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15929 ! has exposure stimulus (-)-methyl jasmonate
relationship: RO:0002309 CHEBI:15929 ! has exposure stimulus (-)-methyl jasmonate

[Term]
id: ECTO:9002364
name: exposure to terpenoid
def: "An exposure to terpenoid." []
synonym: "terpenoid exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26873 ! has exposure stimulus terpenoid
relationship: RO:0002309 CHEBI:26873 ! has exposure stimulus terpenoid

[Term]
id: ECTO:9002365
name: exposure to ferroptosis inducer
def: "An exposure to ferroptosis inducer." []
synonym: "ferroptosis inducer exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:173085 ! has exposure stimulus ferroptosis inducer
relationship: RO:0002309 CHEBI:173085 ! has exposure stimulus ferroptosis inducer

[Term]
id: ECTO:9002366
name: exposure to ferrostatin-1
def: "An exposure to ferrostatin-1." []
synonym: "ferrostatin-1 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:173086 ! has exposure stimulus ferrostatin-1
relationship: RO:0002309 CHEBI:173086 ! has exposure stimulus ferrostatin-1

[Term]
id: ECTO:9002367
name: exposure to ferulic acid
def: "An exposure to ferulic acid." []
synonym: "ferulic acid exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:193350 ! has exposure stimulus ferulic acid
relationship: RO:0002309 CHEBI:193350 ! has exposure stimulus ferulic acid

[Term]
id: ECTO:9002368
name: exposure to roxadustat
def: "An exposure to roxadustat." []
synonym: "roxadustat exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132774 ! has exposure stimulus roxadustat
relationship: RO:0002309 CHEBI:132774 ! has exposure stimulus roxadustat

[Term]
id: ECTO:9002369
name: exposure to fingolimod
def: "An exposure to fingolimod." []
synonym: "fingolimod exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63115 ! has exposure stimulus fingolimod
relationship: RO:0002309 CHEBI:63115 ! has exposure stimulus fingolimod

[Term]
id: ECTO:9002370
name: exposure to fisetin
def: "An exposure to fisetin." []
synonym: "fisetin exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42567 ! has exposure stimulus fisetin
relationship: RO:0002309 CHEBI:42567 ! has exposure stimulus fisetin

[Term]
id: ECTO:9002371
name: exposure to flavonoid
def: "An exposure to flavonoid." []
synonym: "flavonoid exposure" EXACT []
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47916 ! has exposure stimulus flavonoid
relationship: RO:0002309 CHEBI:47916 ! has exposure stimulus flavonoid

[Term]
id: ECTO:9002372
name: exposure to florfenicol
def: "An exposure to florfenicol." []
synonym: "florfenicol exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87185 ! has exposure stimulus florfenicol
relationship: RO:0002309 CHEBI:87185 ! has exposure stimulus florfenicol

[Term]
id: ECTO:9002373
name: exposure to flucloxacillin
def: "An exposure to flucloxacillin." []
synonym: "flucloxacillin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5098 ! has exposure stimulus flucloxacillin
relationship: RO:0002309 CHEBI:5098 ! has exposure stimulus flucloxacillin

[Term]
id: ECTO:9002374
name: exposure to fluoroquinolone antibiotic
def: "An exposure to fluoroquinolone antibiotic." []
synonym: "fluoroquinolone antibiotic exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87211 ! has exposure stimulus fluoroquinolone antibiotic
relationship: RO:0002309 CHEBI:87211 ! has exposure stimulus fluoroquinolone antibiotic

[Term]
id: ECTO:9002375
name: exposure to N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester
def: "An exposure to N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester." []
synonym: "N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:94646 ! has exposure stimulus N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester
relationship: RO:0002309 CHEBI:94646 ! has exposure stimulus N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester

[Term]
id: ECTO:9002376
name: exposure to formononetin
def: "An exposure to formononetin." []
synonym: "formononetin exposure" EXACT []
is_a: ECTO:9000231 ! exposure to hydroxyisoflavone
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18088 ! has exposure stimulus formononetin
relationship: RO:0002309 CHEBI:18088 ! has exposure stimulus formononetin

[Term]
id: ECTO:9002377
name: exposure to fosmidomycin
def: "An exposure to fosmidomycin." []
synonym: "fosmidomycin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001227 ! exposure to phosphorus
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:443725 ! has exposure stimulus fosmidomycin
relationship: RO:0002309 CHEBI:443725 ! has exposure stimulus fosmidomycin

[Term]
id: ECTO:9002378
name: exposure to fraxetin
def: "An exposure to fraxetin." []
synonym: "fraxetin exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000345 ! exposure to phenylpropanoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5169 ! has exposure stimulus fraxetin
relationship: RO:0002309 CHEBI:5169 ! has exposure stimulus fraxetin

[Term]
id: ECTO:9002379
name: exposure to fructooligosaccharide
def: "An exposure to fructooligosaccharide." []
synonym: "fructooligosaccharide exposure" EXACT []
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:190523 ! has exposure stimulus fructooligosaccharide
relationship: RO:0002309 CHEBI:190523 ! has exposure stimulus fructooligosaccharide

[Term]
id: ECTO:9002380
name: exposure to fucoidan
def: "An exposure to fucoidan." []
synonym: "fucoidan exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5181 ! has exposure stimulus fucoidan
relationship: RO:0002309 CHEBI:5181 ! has exposure stimulus fucoidan

[Term]
id: ECTO:9002381
name: exposure to fulvestrant
def: "An exposure to fulvestrant." []
synonym: "fulvestrant exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31638 ! has exposure stimulus fulvestrant
relationship: RO:0002309 CHEBI:31638 ! has exposure stimulus fulvestrant

[Term]
id: ECTO:9002382
name: exposure to metabolite
def: "An exposure to metabolite." []
synonym: "metabolite exposure" EXACT []
is_a: ECTO:0000485 ! exposure to chemical with biological effect
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25212 ! has exposure stimulus metabolite
relationship: RO:0002309 CHEBI:25212 ! has exposure stimulus metabolite

[Term]
id: ECTO:9002383
name: exposure to gadolinium atom
def: "An exposure to gadolinium atom." []
synonym: "gadolinium atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33375 ! has exposure stimulus gadolinium atom
relationship: RO:0002309 CHEBI:33375 ! has exposure stimulus gadolinium atom

[Term]
id: ECTO:9002384
name: exposure to galactoglucomannan
def: "An exposure to galactoglucomannan." []
synonym: "galactoglucomannan exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24144 ! has exposure stimulus galactoglucomannan
relationship: RO:0002309 CHEBI:24144 ! has exposure stimulus galactoglucomannan

[Term]
id: ECTO:9002385
name: exposure to galactose
def: "An exposure to galactose." []
synonym: "galactose exposure" EXACT []
is_a: ECTO:9000164 ! exposure to hexose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28260 ! has exposure stimulus galactose
relationship: RO:0002309 CHEBI:28260 ! has exposure stimulus galactose

[Term]
id: ECTO:9002386
name: exposure to gallic acid
def: "An exposure to gallic acid." []
synonym: "gallic acid exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30778 ! has exposure stimulus gallic acid
relationship: RO:0002309 CHEBI:30778 ! has exposure stimulus gallic acid

[Term]
id: ECTO:9002387
name: exposure to gallium(3+)
def: "An exposure to gallium(3+)." []
synonym: "gallium(3+) exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84043 ! has exposure stimulus gallium(3+)
relationship: RO:0002309 CHEBI:84043 ! has exposure stimulus gallium(3+)

[Term]
id: ECTO:9002388
name: exposure to gefitinib
def: "An exposure to gefitinib." []
synonym: "gefitinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49668 ! has exposure stimulus gefitinib
relationship: RO:0002309 CHEBI:49668 ! has exposure stimulus gefitinib

[Term]
id: ECTO:9002389
name: exposure to starch
def: "An exposure to starch." []
synonym: "starch exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28017 ! has exposure stimulus starch
relationship: RO:0002309 CHEBI:28017 ! has exposure stimulus starch

[Term]
id: ECTO:9002390
name: exposure to gemfibrozil
def: "An exposure to gemfibrozil." []
synonym: "gemfibrozil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5296 ! has exposure stimulus gemfibrozil
relationship: RO:0002309 CHEBI:5296 ! has exposure stimulus gemfibrozil

[Term]
id: ECTO:9002391
name: exposure to gentamicin
def: "An exposure to gentamycin." []
synonym: "gentamycin exposure" EXACT []
is_a: ECTO:9002231 ! exposure to aminoglycoside antibiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17833 ! has exposure stimulus gentamycin
relationship: RO:0002309 CHEBI:17833 ! has exposure stimulus gentamycin

[Term]
id: ECTO:9002392
name: exposure to gentamicin sulfate
def: "An exposure to gentamicin sulfate." []
synonym: "gentamicin sulfate exposure" EXACT []
is_a: ECTO:9000404 ! exposure to nitrogen
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9002391 ! exposure to gentamicin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5312 ! has exposure stimulus gentamicin sulfate
relationship: RO:0002309 CHEBI:5312 ! has exposure stimulus gentamicin sulfate

[Term]
id: ECTO:9002393
name: exposure to Gibberellic acid
def: "An exposure to Gibberellic acid." []
synonym: "Gibberellic acid exposure" EXACT []
is_a: ECTO:9000160 ! exposure to gibberellin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:86644 ! has exposure stimulus Gibberellic acid
relationship: RO:0002309 CHEBI:86644 ! has exposure stimulus Gibberellic acid

[Term]
id: ECTO:9002394
name: exposure to gilteritinib
def: "An exposure to gilteritinib." []
synonym: "gilteritinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:145372 ! has exposure stimulus gilteritinib
relationship: RO:0002309 CHEBI:145372 ! has exposure stimulus gilteritinib

[Term]
id: ECTO:9002395
name: exposure to ginsenoside Re
def: "An exposure to ginsenoside Re." []
synonym: "ginsenoside Re exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000495 ! exposure to glucoside
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:77148 ! has exposure stimulus ginsenoside Re
relationship: RO:0002309 CHEBI:77148 ! has exposure stimulus ginsenoside Re

[Term]
id: ECTO:9002396
name: exposure to gliadin
def: "An exposure to gliadin." []
synonym: "gliadin exposure" EXACT []
is_a: ECTO:9002133 ! exposure to protein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:190522 ! has exposure stimulus gliadin
relationship: RO:0002309 CHEBI:190522 ! has exposure stimulus gliadin

[Term]
id: ECTO:9002397
name: exposure to glipizide
def: "An exposure to glipizide." []
synonym: "glipizide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5384 ! has exposure stimulus glipizide
relationship: RO:0002309 CHEBI:5384 ! has exposure stimulus glipizide

[Term]
id: ECTO:9002398
name: exposure to triamcinolone acetonide
def: "An exposure to triamcinolone acetonide." []
synonym: "triamcinolone acetonide exposure" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71418 ! has exposure stimulus triamcinolone acetonide
relationship: RO:0002309 CHEBI:71418 ! has exposure stimulus triamcinolone acetonide

[Term]
id: ECTO:9002399
name: exposure to glutamate(2-)
def: "An exposure to glutamate(2-)." []
synonym: "glutamate(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29987 ! has exposure stimulus glutamate(2-)
relationship: RO:0002309 CHEBI:29987 ! has exposure stimulus glutamate(2-)

[Term]
id: ECTO:9002400
name: exposure to glutamic acid
def: "An exposure to glutamic acid." []
synonym: "glutamic acid exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18237 ! has exposure stimulus glutamic acid
relationship: RO:0002309 CHEBI:18237 ! has exposure stimulus glutamic acid

[Term]
id: ECTO:9002401
name: exposure to glycine
def: "An exposure to glycine." []
synonym: "glycine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15428 ! has exposure stimulus glycine
relationship: RO:0002309 CHEBI:15428 ! has exposure stimulus glycine

[Term]
id: ECTO:9002402
name: exposure to Gly-Pro
def: "An exposure to Gly-Pro." []
synonym: "Gly-Pro exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70744 ! has exposure stimulus Gly-Pro
relationship: RO:0002309 CHEBI:70744 ! has exposure stimulus Gly-Pro

[Term]
id: ECTO:9002403
name: exposure to glycyrrhetinic acid
def: "An exposure to glycyrrhetinic acid." []
synonym: "glycyrrhetinic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30853 ! has exposure stimulus glycyrrhetinic acid
relationship: RO:0002309 CHEBI:30853 ! has exposure stimulus glycyrrhetinic acid

[Term]
id: ECTO:9002404
name: exposure to glycyrrhizinic acid
def: "An exposure to glycyrrhizinic acid." []
synonym: "glycyrrhizinic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000239 ! exposure to monosaccharide
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15939 ! has exposure stimulus glycyrrhizinic acid
relationship: RO:0002309 CHEBI:15939 ! has exposure stimulus glycyrrhizinic acid

[Term]
id: ECTO:9002405
name: exposure to glyoxal
def: "An exposure to glyoxal." []
synonym: "glyoxal exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34779 ! has exposure stimulus glyoxal
relationship: RO:0002309 CHEBI:34779 ! has exposure stimulus glyoxal

[Term]
id: ECTO:9002406
name: exposure to triptorelin
def: "An exposure to triptorelin." []
synonym: "triptorelin exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63633 ! has exposure stimulus triptorelin
relationship: RO:0002309 CHEBI:63633 ! has exposure stimulus triptorelin

[Term]
id: ECTO:9002407
name: exposure to growth hormone
def: "An exposure to growth hormone." []
synonym: "growth hormone exposure" EXACT []
is_a: ECTO:0000516 ! exposure to hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37845 ! has exposure stimulus growth hormone
relationship: RO:0002309 CHEBI:37845 ! has exposure stimulus growth hormone

[Term]
id: ECTO:9002408
name: exposure to guanidinoacetic acid
def: "An exposure to guanidinoacetic acid." []
synonym: "guanidinoacetic acid exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16344 ! has exposure stimulus guanidinoacetic acid
relationship: RO:0002309 CHEBI:16344 ! has exposure stimulus guanidinoacetic acid

[Term]
id: ECTO:9002409
name: exposure to guanosine
def: "An exposure to guanosine." []
synonym: "guanosine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16750 ! has exposure stimulus guanosine
relationship: RO:0002309 CHEBI:16750 ! has exposure stimulus guanosine

[Term]
id: ECTO:9002410
name: exposure to gut flora metabolite
def: "An exposure to gut flora metabolite." []
synonym: "gut flora metabolite exposure" EXACT []
is_a: ECTO:9002382 ! exposure to metabolite
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82933 ! has exposure stimulus gut flora metabolite
relationship: RO:0002309 CHEBI:82933 ! has exposure stimulus gut flora metabolite

[Term]
id: ECTO:9002411
name: exposure to GW 501516
def: "An exposure to GW 501516." []
synonym: "GW 501516 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73726 ! has exposure stimulus GW 501516
relationship: RO:0002309 CHEBI:73726 ! has exposure stimulus GW 501516

[Term]
id: ECTO:9002412
name: exposure to haloacetic acid
def: "An exposure to haloacetic acid." []
synonym: "haloacetic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16277 ! has exposure stimulus haloacetic acid
relationship: RO:0002309 CHEBI:16277 ! has exposure stimulus haloacetic acid

[Term]
id: ECTO:9002413
name: exposure to helenalin
def: "An exposure to helenalin." []
synonym: "helenalin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5635 ! has exposure stimulus helenalin
relationship: RO:0002309 CHEBI:5635 ! has exposure stimulus helenalin

[Term]
id: ECTO:9002414
name: exposure to Heptelidic acid
def: "An exposure to Heptelidic acid." []
synonym: "Heptelidic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:214314 ! has exposure stimulus Heptelidic acid
relationship: RO:0002309 CHEBI:214314 ! has exposure stimulus Heptelidic acid

[Term]
id: ECTO:9002415
name: exposure to hexachlorocyclohexane
def: "An exposure to hexachlorocyclohexane." []
synonym: "hexachlorocyclohexane exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24536 ! has exposure stimulus hexachlorocyclohexane
relationship: RO:0002309 CHEBI:24536 ! has exposure stimulus hexachlorocyclohexane

[Term]
id: ECTO:9002416
name: exposure to insulin
def: "An exposure to insulin." []
synonym: "insulin exposure" EXACT []
is_a: ECTO:9000273 ! exposure to peptide hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:145810 ! has exposure stimulus insulin
relationship: RO:0002309 CHEBI:145810 ! has exposure stimulus insulin

[Term]
id: ECTO:9002418
name: exposure to homovanillic acid
def: "An exposure to homovanillic acid." []
synonym: "homovanillic acid exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:545959 ! has exposure stimulus homovanillic acid
relationship: RO:0002309 CHEBI:545959 ! has exposure stimulus homovanillic acid

[Term]
id: ECTO:9002419
name: exposure to hydroxychloroquine
def: "An exposure to hydroxychloroquine." []
synonym: "hydroxychloroquine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5801 ! has exposure stimulus hydroxychloroquine
relationship: RO:0002309 CHEBI:5801 ! has exposure stimulus hydroxychloroquine

[Term]
id: ECTO:9002420
name: exposure to hyodeoxycholic acid
def: "An exposure to hyodeoxycholic acid." []
synonym: "hyodeoxycholic acid exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52023 ! has exposure stimulus hyodeoxycholic acid
relationship: RO:0002309 CHEBI:52023 ! has exposure stimulus hyodeoxycholic acid

[Term]
id: ECTO:9002421
name: exposure to ibrutinib
def: "An exposure to ibrutinib." []
synonym: "ibrutinib exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002871 ! exposure to pyrazolopyrimidine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76612 ! has exposure stimulus ibrutinib
relationship: RO:0002309 CHEBI:76612 ! has exposure stimulus ibrutinib

[Term]
id: ECTO:9002422
name: exposure to idarubicin
def: "An exposure to idarubicin." []
synonym: "idarubicin exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9002237 ! exposure to anthracycline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42068 ! has exposure stimulus idarubicin
relationship: RO:0002309 CHEBI:42068 ! has exposure stimulus idarubicin

[Term]
id: ECTO:9002423
name: exposure to GSK864
def: "An exposure to GSK864." []
synonym: "GSK864 exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233361 ! has exposure stimulus GSK864
relationship: RO:0002309 CHEBI:233361 ! has exposure stimulus GSK864

[Term]
id: ECTO:9002424
name: exposure to imipramine hydrochloride
def: "An exposure to imipramine hydrochloride." []
synonym: "imipramine hydrochloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5882 ! has exposure stimulus imipramine hydrochloride
relationship: RO:0002309 CHEBI:5882 ! has exposure stimulus imipramine hydrochloride

[Term]
id: ECTO:9002425
name: exposure to chenodeoxycholic acid
def: "An exposure to chenodeoxycholic acid." []
synonym: "chenodeoxycholic acid exposure" EXACT []
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16755 ! has exposure stimulus chenodeoxycholic acid
relationship: RO:0002309 CHEBI:16755 ! has exposure stimulus chenodeoxycholic acid

[Term]
id: ECTO:9002426
name: exposure to indoxyl sulfate
def: "An exposure to indoxyl sulfate." []
synonym: "indoxyl sulfate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43355 ! has exposure stimulus indoxyl sulfate
relationship: RO:0002309 CHEBI:43355 ! has exposure stimulus indoxyl sulfate

[Term]
id: ECTO:9002427
name: exposure to indoxyl sulfate(1-)
def: "An exposure to indoxyl sulfate(1-)." []
synonym: "indoxyl sulfate(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:144643 ! has exposure stimulus indoxyl sulfate(1-)
relationship: RO:0002309 CHEBI:144643 ! has exposure stimulus indoxyl sulfate(1-)

[Term]
id: ECTO:9002428
name: exposure to insulin (human)
def: "An exposure to insulin (human)." []
synonym: "insulin (human) exposure" EXACT []
is_a: ECTO:9002416 ! exposure to insulin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5931 ! has exposure stimulus insulin (human)
relationship: RO:0002309 CHEBI:5931 ! has exposure stimulus insulin (human)

[Term]
id: ECTO:9002429
name: exposure to Interferon beta-1b
def: "An exposure to Interferon beta-1b." []
synonym: "Interferon beta-1b exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5938 ! has exposure stimulus Interferon beta-1b
relationship: RO:0002309 CHEBI:5938 ! has exposure stimulus Interferon beta-1b

[Term]
id: ECTO:9002430
name: exposure to irinotecan hydrochloride (anhydrous)
def: "An exposure to irinotecan hydrochloride (anhydrous)." []
synonym: "irinotecan hydrochloride (anhydrous) exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5971 ! has exposure stimulus irinotecan hydrochloride (anhydrous)
relationship: RO:0002309 CHEBI:5971 ! has exposure stimulus irinotecan hydrochloride (anhydrous)

[Term]
id: ECTO:9002431
name: exposure to iron oxide nanoparticle
def: "An exposure to iron oxide nanoparticle." []
synonym: "iron oxide nanoparticle exposure" EXACT []
is_a: ECTO:9002233 ! exposure to nanoparticle
is_a: ECTO:9002623 ! exposure to iron oxide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50822 ! has exposure stimulus iron oxide nanoparticle
relationship: RO:0002309 CHEBI:50822 ! has exposure stimulus iron oxide nanoparticle

[Term]
id: ECTO:9002432
name: exposure to isoxaben
def: "An exposure to isoxaben." []
synonym: "isoxaben exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63956 ! has exposure stimulus isoxaben
relationship: RO:0002309 CHEBI:63956 ! has exposure stimulus isoxaben

[Term]
id: ECTO:9002433
name: exposure to itaconic acid
def: "An exposure to itaconic acid." []
synonym: "itaconic acid exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30838 ! has exposure stimulus itaconic acid
relationship: RO:0002309 CHEBI:30838 ! has exposure stimulus itaconic acid

[Term]
id: ECTO:9002434
name: exposure to itaconate(2-)
def: "An exposure to itaconate(2-)." []
synonym: "itaconate(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17240 ! has exposure stimulus itaconate(2-)
relationship: RO:0002309 CHEBI:17240 ! has exposure stimulus itaconate(2-)

[Term]
id: ECTO:9002435
name: exposure to itraconazole
def: "An exposure to itraconazole." []
synonym: "itraconazole exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6076 ! has exposure stimulus itraconazole
relationship: RO:0002309 CHEBI:6076 ! has exposure stimulus itraconazole

[Term]
id: ECTO:9002436
name: exposure to ivermectin
def: "An exposure to ivermectin." []
synonym: "ivermectin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6078 ! has exposure stimulus ivermectin
relationship: RO:0002309 CHEBI:6078 ! has exposure stimulus ivermectin

[Term]
id: ECTO:9002437
name: exposure to ketoconazole
def: "An exposure to ketoconazole." []
synonym: "ketoconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47519 ! has exposure stimulus ketoconazole
relationship: RO:0002309 CHEBI:47519 ! has exposure stimulus ketoconazole

[Term]
id: ECTO:9002438
name: exposure to kojic acid
def: "An exposure to kojic acid." []
synonym: "kojic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43572 ! has exposure stimulus kojic acid
relationship: RO:0002309 CHEBI:43572 ! has exposure stimulus kojic acid

[Term]
id: ECTO:9002439
name: exposure to KP1339
def: "An exposure to KP1339." []
synonym: "KP1339 exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:176975 ! has exposure stimulus KP1339
relationship: RO:0002309 CHEBI:176975 ! has exposure stimulus KP1339

[Term]
id: ECTO:9002440
name: exposure to krypton (81mKr) gas
def: "An exposure to krypton (81mKr) gas." []
synonym: "krypton (81mKr) gas exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:136002 ! has exposure stimulus krypton (81mKr) gas
relationship: RO:0002309 CHEBI:136002 ! has exposure stimulus krypton (81mKr) gas

[Term]
id: ECTO:9002441
name: exposure to kynurenine
def: "An exposure to kynurenine." []
synonym: "kynurenine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28683 ! has exposure stimulus kynurenine
relationship: RO:0002309 CHEBI:28683 ! has exposure stimulus kynurenine

[Term]
id: ECTO:9002442
name: exposure to L-ascorbic acid 2-phosphate
def: "An exposure to L-ascorbic acid 2-phosphate." []
synonym: "L-ascorbic acid 2-phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:167162 ! has exposure stimulus L-ascorbic acid 2-phosphate
relationship: RO:0002309 CHEBI:167162 ! has exposure stimulus L-ascorbic acid 2-phosphate

[Term]
id: ECTO:9002443
name: exposure to L-buthionine-(S,R)-sulfoximine
def: "An exposure to L-buthionine-(S,R)-sulfoximine." []
synonym: "L-buthionine-(S,R)-sulfoximine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:94288 ! has exposure stimulus L-buthionine-(S,R)-sulfoximine
relationship: RO:0002309 CHEBI:94288 ! has exposure stimulus L-buthionine-(S,R)-sulfoximine

[Term]
id: ECTO:9002444
name: exposure to carnitine
def: "An exposure to carnitine." []
synonym: "carnitine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17126 ! has exposure stimulus carnitine
relationship: RO:0002309 CHEBI:17126 ! has exposure stimulus carnitine

[Term]
id: ECTO:9002445
name: exposure to L-citrulline
def: "An exposure to L-citrulline." []
synonym: "L-citrulline exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16349 ! has exposure stimulus L-citrulline
relationship: RO:0002309 CHEBI:16349 ! has exposure stimulus L-citrulline

[Term]
id: ECTO:9002446
name: exposure to L-fucose
def: "An exposure to L-fucose." []
synonym: "L-fucose exposure" EXACT []
is_a: ECTO:9000164 ! exposure to hexose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18287 ! has exposure stimulus L-fucose
relationship: RO:0002309 CHEBI:18287 ! has exposure stimulus L-fucose

[Term]
id: ECTO:9002447
name: exposure to L-glyceraldehyde
def: "An exposure to L-glyceraldehyde." []
synonym: "L-glyceraldehyde exposure" EXACT []
is_a: ECTO:9000239 ! exposure to monosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27975 ! has exposure stimulus L-glyceraldehyde
relationship: RO:0002309 CHEBI:27975 ! has exposure stimulus L-glyceraldehyde

[Term]
id: ECTO:9002448
name: exposure to L-serine
def: "An exposure to L-serine." []
synonym: "L-serine exposure" EXACT []
is_a: ECTO:9002700 ! exposure to serine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17115 ! has exposure stimulus L-serine
relationship: RO:0002309 CHEBI:17115 ! has exposure stimulus L-serine

[Term]
id: ECTO:9002449
name: exposure to labetalol
def: "An exposure to labetalol." []
synonym: "labetalol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6343 ! has exposure stimulus labetalol
relationship: RO:0002309 CHEBI:6343 ! has exposure stimulus labetalol

[Term]
id: ECTO:9002450
name: exposure to lactate
def: "An exposure to lactate." []
synonym: "lactate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24996 ! has exposure stimulus lactate
relationship: RO:0002309 CHEBI:24996 ! has exposure stimulus lactate

[Term]
id: ECTO:9002451
name: exposure to lactose
def: "An exposure to lactose." []
synonym: "lactose exposure" EXACT []
is_a: ECTO:9000240 ! exposure to disaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17716 ! has exposure stimulus lactose
relationship: RO:0002309 CHEBI:17716 ! has exposure stimulus lactose

[Term]
id: ECTO:9002452
name: exposure to lead(2+)
def: "An exposure to lead(2+)." []
synonym: "lead(2+) exposure" EXACT []
is_a: ECTO:9000194 ! exposure to lead cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49807 ! has exposure stimulus lead(2+)
relationship: RO:0002309 CHEBI:49807 ! has exposure stimulus lead(2+)

[Term]
id: ECTO:9002453
name: exposure to lead nitrate
def: "An exposure to lead nitrate." []
synonym: "lead nitrate exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9000945 ! exposure to lead
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37187 ! has exposure stimulus lead nitrate
relationship: RO:0002309 CHEBI:37187 ! has exposure stimulus lead nitrate

[Term]
id: ECTO:9002454
name: exposure to leflunomide
def: "An exposure to leflunomide." []
synonym: "leflunomide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6402 ! has exposure stimulus leflunomide
relationship: RO:0002309 CHEBI:6402 ! has exposure stimulus leflunomide

[Term]
id: ECTO:9002455
name: exposure to lenalidomide
def: "An exposure to lenalidomide." []
synonym: "lenalidomide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63791 ! has exposure stimulus lenalidomide
relationship: RO:0002309 CHEBI:63791 ! has exposure stimulus lenalidomide

[Term]
id: ECTO:9002456
name: exposure to lesinurad
def: "An exposure to lesinurad." []
synonym: "lesinurad exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:90929 ! has exposure stimulus lesinurad
relationship: RO:0002309 CHEBI:90929 ! has exposure stimulus lesinurad

[Term]
id: ECTO:9002457
name: exposure to letrozole
def: "An exposure to letrozole." []
synonym: "letrozole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6413 ! has exposure stimulus letrozole
relationship: RO:0002309 CHEBI:6413 ! has exposure stimulus letrozole

[Term]
id: ECTO:9002458
name: exposure to levofloxacin
def: "An exposure to levofloxacin." []
synonym: "levofloxacin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002374 ! exposure to fluoroquinolone antibiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63598 ! has exposure stimulus levofloxacin
relationship: RO:0002309 CHEBI:63598 ! has exposure stimulus levofloxacin

[Term]
id: ECTO:9002459
name: exposure to levonorgestrel
def: "An exposure to levonorgestrel." []
synonym: "levonorgestrel exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6443 ! has exposure stimulus levonorgestrel
relationship: RO:0002309 CHEBI:6443 ! has exposure stimulus levonorgestrel

[Term]
id: ECTO:9002460
name: exposure to lignin
def: "An exposure to lignin." []
synonym: "lignin exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6457 ! has exposure stimulus lignin
relationship: RO:0002309 CHEBI:6457 ! has exposure stimulus lignin

[Term]
id: ECTO:9002461
name: exposure to lignocellulose
def: "An exposure to lignocellulose." []
synonym: "lignocellulose exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:180683 ! has exposure stimulus lignocellulose
relationship: RO:0002309 CHEBI:180683 ! has exposure stimulus lignocellulose

[Term]
id: ECTO:9002462
name: exposure to linezolid
def: "An exposure to linezolid." []
synonym: "linezolid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63607 ! has exposure stimulus linezolid
relationship: RO:0002309 CHEBI:63607 ! has exposure stimulus linezolid

[Term]
id: ECTO:9002463
name: exposure to loperamide hydrochloride
def: "An exposure to loperamide hydrochloride." []
synonym: "loperamide hydrochloride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6533 ! has exposure stimulus loperamide hydrochloride
relationship: RO:0002309 CHEBI:6533 ! has exposure stimulus loperamide hydrochloride

[Term]
id: ECTO:9002464
name: exposure to loperamide
def: "An exposure to loperamide." []
synonym: "loperamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6532 ! has exposure stimulus loperamide
relationship: RO:0002309 CHEBI:6532 ! has exposure stimulus loperamide

[Term]
id: ECTO:9002465
name: exposure to magnesium atom
def: "An exposure to magnesium atom." []
synonym: "magnesium atom exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25107 ! has exposure stimulus magnesium atom
relationship: RO:0002309 CHEBI:25107 ! has exposure stimulus magnesium atom

[Term]
id: ECTO:9002467
name: exposure to loxoprofen
def: "An exposure to loxoprofen." []
synonym: "loxoprofen exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76172 ! has exposure stimulus loxoprofen
relationship: RO:0002309 CHEBI:76172 ! has exposure stimulus loxoprofen

[Term]
id: ECTO:9002468
name: exposure to lysophosphatidic acid 16:0
def: "An exposure to lysophosphatidic acid 16:0." []
synonym: "lysophosphatidic acid 16:0 exposure" EXACT []
is_a: ECTO:9002689 ! exposure to lysophosphatidic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132744 ! has exposure stimulus lysophosphatidic acid 16:0
relationship: RO:0002309 CHEBI:132744 ! has exposure stimulus lysophosphatidic acid 16:0

[Term]
id: ECTO:9002469
name: exposure to lumiracoxib
def: "An exposure to lumiracoxib." []
synonym: "lumiracoxib exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73044 ! has exposure stimulus lumiracoxib
relationship: RO:0002309 CHEBI:73044 ! has exposure stimulus lumiracoxib

[Term]
id: ECTO:9002470
name: exposure to lurasidone
def: "An exposure to lurasidone." []
synonym: "lurasidone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70735 ! has exposure stimulus lurasidone
relationship: RO:0002309 CHEBI:70735 ! has exposure stimulus lurasidone

[Term]
id: ECTO:9002471
name: exposure to lysophosphatidylcholine
def: "An exposure to lysophosphatidylcholine." []
synonym: "lysophosphatidylcholine exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000304 ! exposure to ammonium ion
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60479 ! has exposure stimulus lysophosphatidylcholine
relationship: RO:0002309 CHEBI:60479 ! has exposure stimulus lysophosphatidylcholine

[Term]
id: ECTO:9002472
name: exposure to Magnesium perchlorate
def: "An exposure to Magnesium perchlorate." []
synonym: "Magnesium perchlorate exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:184579 ! has exposure stimulus Magnesium perchlorate
relationship: RO:0002309 CHEBI:184579 ! has exposure stimulus Magnesium perchlorate

[Term]
id: ECTO:9002473
name: exposure to manganese atom
def: "An exposure to manganese atom." []
synonym: "manganese atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18291 ! has exposure stimulus manganese atom
relationship: RO:0002309 CHEBI:18291 ! has exposure stimulus manganese atom

[Term]
id: ECTO:9002474
name: exposure to mannan
def: "An exposure to mannan." []
synonym: "mannan exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28808 ! has exposure stimulus mannan
relationship: RO:0002309 CHEBI:28808 ! has exposure stimulus mannan

[Term]
id: ECTO:9002475
name: exposure to mannose
def: "An exposure to mannose." []
synonym: "mannose exposure" EXACT []
is_a: ECTO:9000164 ! exposure to hexose
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37684 ! has exposure stimulus mannose
relationship: RO:0002309 CHEBI:37684 ! has exposure stimulus mannose

[Term]
id: ECTO:9002476
name: exposure to maslinic acid
def: "An exposure to maslinic acid." []
synonym: "maslinic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:66682 ! has exposure stimulus maslinic acid
relationship: RO:0002309 CHEBI:66682 ! has exposure stimulus maslinic acid

[Term]
id: ECTO:9002477
name: exposure to poly(I:C)
def: "An exposure to poly(I:C)." []
synonym: "poly(I:C) exposure" EXACT []
is_a: ECTO:9000272 ! exposure to double-stranded RNA
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84491 ! has exposure stimulus poly(I:C)
relationship: RO:0002309 CHEBI:84491 ! has exposure stimulus poly(I:C)

[Term]
id: ECTO:9002478
name: exposure to nicotinamide
def: "An exposure to nicotinamide." []
synonym: "nicotinamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
is_a: ECTO:9002845 ! exposure to vitamin B3
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17154 ! has exposure stimulus nicotinamide
relationship: RO:0002309 CHEBI:17154 ! has exposure stimulus nicotinamide

[Term]
id: ECTO:9002479
name: exposure to MCC950
def: "An exposure to MCC950." []
synonym: "MCC950 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:231684 ! has exposure stimulus MCC950
relationship: RO:0002309 CHEBI:231684 ! has exposure stimulus MCC950

[Term]
id: ECTO:9002480
name: exposure to trametinib dimethyl sulfoxide
def: "An exposure to trametinib dimethyl sulfoxide." []
synonym: "trametinib dimethyl sulfoxide exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75991 ! has exposure stimulus trametinib dimethyl sulfoxide
relationship: RO:0002309 CHEBI:75991 ! has exposure stimulus trametinib dimethyl sulfoxide

[Term]
id: ECTO:9002481
name: exposure to melatonin
def: "An exposure to melatonin." []
synonym: "melatonin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16796 ! has exposure stimulus melatonin
relationship: RO:0002309 CHEBI:16796 ! has exposure stimulus melatonin

[Term]
id: ECTO:9002482
name: exposure to melphalan
def: "An exposure to melphalan." []
synonym: "melphalan exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9000470 ! exposure to L-phenylalanine derivative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28876 ! has exposure stimulus melphalan
relationship: RO:0002309 CHEBI:28876 ! has exposure stimulus melphalan

[Term]
id: ECTO:9002483
name: exposure to memantine
def: "An exposure to memantine." []
synonym: "memantine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64312 ! has exposure stimulus memantine
relationship: RO:0002309 CHEBI:64312 ! has exposure stimulus memantine

[Term]
id: ECTO:9002484
name: exposure to mercury atom
def: "An exposure to mercury atom." []
synonym: "mercury atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25195 ! has exposure stimulus mercury atom
relationship: RO:0002309 CHEBI:25195 ! has exposure stimulus mercury atom

[Term]
id: ECTO:9002485
name: exposure to mercury(2+)
def: "An exposure to mercury(2+)." []
synonym: "mercury(2+) exposure" EXACT []
is_a: ECTO:9000289 ! exposure to mercury cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16793 ! has exposure stimulus mercury(2+)
relationship: RO:0002309 CHEBI:16793 ! has exposure stimulus mercury(2+)

[Term]
id: ECTO:9002486
name: exposure to meropenem
def: "An exposure to meropenem." []
synonym: "meropenem exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43968 ! has exposure stimulus meropenem
relationship: RO:0002309 CHEBI:43968 ! has exposure stimulus meropenem

[Term]
id: ECTO:9002487
name: exposure to mesalamine
def: "An exposure to mesalamine." []
synonym: "mesalamine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6775 ! has exposure stimulus mesalamine
relationship: RO:0002309 CHEBI:6775 ! has exposure stimulus mesalamine

[Term]
id: ECTO:9002488
name: exposure to methimazole
def: "An exposure to methimazole." []
synonym: "methimazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50673 ! has exposure stimulus methimazole
relationship: RO:0002309 CHEBI:50673 ! has exposure stimulus methimazole

[Term]
id: ECTO:9002489
name: exposure to methylphenidate hydrochloride
def: "An exposure to methylphenidate hydrochloride." []
synonym: "methylphenidate hydrochloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31836 ! has exposure stimulus methylphenidate hydrochloride
relationship: RO:0002309 CHEBI:31836 ! has exposure stimulus methylphenidate hydrochloride

[Term]
id: ECTO:9002490
name: exposure to midazolam
def: "An exposure to midazolam." []
synonym: "midazolam exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6931 ! has exposure stimulus midazolam
relationship: RO:0002309 CHEBI:6931 ! has exposure stimulus midazolam

[Term]
id: ECTO:9002491
name: exposure to miltefosine
def: "An exposure to miltefosine." []
synonym: "miltefosine exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000304 ! exposure to ammonium ion
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75283 ! has exposure stimulus miltefosine
relationship: RO:0002309 CHEBI:75283 ! has exposure stimulus miltefosine

[Term]
id: ECTO:9002492
name: exposure to mirabegron
def: "An exposure to mirabegron." []
synonym: "mirabegron exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65349 ! has exposure stimulus mirabegron
relationship: RO:0002309 CHEBI:65349 ! has exposure stimulus mirabegron

[Term]
id: ECTO:9002493
name: exposure to mitomycin C
def: "An exposure to mitomycin C." []
synonym: "mitomycin C exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27504 ! has exposure stimulus mitomycin C
relationship: RO:0002309 CHEBI:27504 ! has exposure stimulus mitomycin C

[Term]
id: ECTO:9002494
name: exposure to mitoquinone mesylate
def: "An exposure to mitoquinone mesylate." []
synonym: "mitoquinone mesylate exposure" EXACT []
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:234429 ! has exposure stimulus mitoquinone mesylate
relationship: RO:0002309 CHEBI:234429 ! has exposure stimulus mitoquinone mesylate

[Term]
id: ECTO:9002495
name: exposure to Mitoquinone
def: "An exposure to Mitoquinone." []
synonym: "Mitoquinone exposure" EXACT []
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233321 ! has exposure stimulus Mitoquinone
relationship: RO:0002309 CHEBI:233321 ! has exposure stimulus Mitoquinone

[Term]
id: ECTO:9002496
name: exposure to MitoTEMPO
def: "An exposure to MitoTEMPO." []
synonym: "MitoTEMPO exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:232424 ! has exposure stimulus MitoTEMPO
relationship: RO:0002309 CHEBI:232424 ! has exposure stimulus MitoTEMPO

[Term]
id: ECTO:9002497
name: exposure to mitoxantrone
def: "An exposure to mitoxantrone." []
synonym: "mitoxantrone exposure" EXACT []
is_a: ECTO:9001246 ! exposure to quinone
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50729 ! has exposure stimulus mitoxantrone
relationship: RO:0002309 CHEBI:50729 ! has exposure stimulus mitoxantrone

[Term]
id: ECTO:9002498
name: exposure to monensin A
def: "An exposure to monensin A." []
synonym: "monensin A exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27617 ! has exposure stimulus monensin A
relationship: RO:0002309 CHEBI:27617 ! has exposure stimulus monensin A

[Term]
id: ECTO:9002499
name: exposure to monocrotaline
def: "An exposure to monocrotaline." []
synonym: "monocrotaline exposure" EXACT []
is_a: ECTO:9002577 ! exposure to pyrrolizidine alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6980 ! has exposure stimulus monocrotaline
relationship: RO:0002309 CHEBI:6980 ! has exposure stimulus monocrotaline

[Term]
id: ECTO:9002500
name: exposure to monosodium urate
def: "An exposure to monosodium urate." []
synonym: "monosodium urate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:143125 ! has exposure stimulus monosodium urate
relationship: RO:0002309 CHEBI:143125 ! has exposure stimulus monosodium urate

[Term]
id: ECTO:9002501
name: exposure to montelukast
def: "An exposure to montelukast." []
synonym: "montelukast exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50730 ! has exposure stimulus montelukast
relationship: RO:0002309 CHEBI:50730 ! has exposure stimulus montelukast

[Term]
id: ECTO:9002502
name: exposure to montelukast(1-)
def: "An exposure to montelukast(1-)." []
synonym: "montelukast(1-) exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49165 ! has exposure stimulus montelukast(1-)
relationship: RO:0002309 CHEBI:49165 ! has exposure stimulus montelukast(1-)

[Term]
id: ECTO:9002503
name: exposure to Ku-0063794
def: "An exposure to Ku-0063794." []
synonym: "Ku-0063794 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85572 ! has exposure stimulus Ku-0063794
relationship: RO:0002309 CHEBI:85572 ! has exposure stimulus Ku-0063794

[Term]
id: ECTO:9002504
name: exposure to chlorine oxoanion
def: "An exposure to chlorine oxoanion." []
synonym: "chlorine oxoanion exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33437 ! has exposure stimulus chlorine oxoanion
relationship: RO:0002309 CHEBI:33437 ! has exposure stimulus chlorine oxoanion

[Term]
id: ECTO:9002505
name: exposure to oxidised LDL
def: "An exposure to oxidised LDL." []
synonym: "oxidised LDL exposure" EXACT []
is_a: ECTO:9002134 ! exposure to low-density lipoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60151 ! has exposure stimulus oxidised LDL
relationship: RO:0002309 CHEBI:60151 ! has exposure stimulus oxidised LDL

[Term]
id: ECTO:9002506
name: exposure to myricetin
def: "An exposure to myricetin." []
synonym: "myricetin exposure" EXACT []
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18152 ! has exposure stimulus myricetin
relationship: RO:0002309 CHEBI:18152 ! has exposure stimulus myricetin

[Term]
id: ECTO:9002507
name: exposure to polyunsaturated fatty acid
def: "An exposure to polyunsaturated fatty acid." []
synonym: "polyunsaturated fatty acid exposure" EXACT []
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26208 ! has exposure stimulus polyunsaturated fatty acid
relationship: RO:0002309 CHEBI:26208 ! has exposure stimulus polyunsaturated fatty acid

[Term]
id: ECTO:9002508
name: exposure to N-acetyl-L-cysteine
def: "An exposure to N-acetyl-L-cysteine." []
synonym: "N-acetyl-L-cysteine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28939 ! has exposure stimulus N-acetyl-L-cysteine
relationship: RO:0002309 CHEBI:28939 ! has exposure stimulus N-acetyl-L-cysteine

[Term]
id: ECTO:9002509
name: exposure to N-carbamoylglutamate(2-)
def: "An exposure to N-carbamoylglutamate(2-)." []
synonym: "N-carbamoylglutamate(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233559 ! has exposure stimulus N-carbamoylglutamate(2-)
relationship: RO:0002309 CHEBI:233559 ! has exposure stimulus N-carbamoylglutamate(2-)

[Term]
id: ECTO:9002510
name: exposure to N(8)-acetylspermidinium(2+)
def: "An exposure to N(8)-acetylspermidinium(2+)." []
synonym: "N(8)-acetylspermidinium(2+) exposure" EXACT []
is_a: ECTO:9000304 ! exposure to ammonium ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:58535 ! has exposure stimulus N(8)-acetylspermidinium(2+)
relationship: RO:0002309 CHEBI:58535 ! has exposure stimulus N(8)-acetylspermidinium(2+)

[Term]
id: ECTO:9002511
name: exposure to nevirapine
def: "An exposure to nevirapine." []
synonym: "nevirapine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63613 ! has exposure stimulus nevirapine
relationship: RO:0002309 CHEBI:63613 ! has exposure stimulus nevirapine

[Term]
id: ECTO:9002512
name: exposure to nickel(2+)
def: "An exposure to nickel(2+)." []
synonym: "nickel(2+) exposure" EXACT []
is_a: ECTO:9000182 ! exposure to nickel cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49786 ! has exposure stimulus nickel(2+)
relationship: RO:0002309 CHEBI:49786 ! has exposure stimulus nickel(2+)

[Term]
id: ECTO:9002513
name: exposure to nigericin
def: "An exposure to nigericin." []
synonym: "nigericin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7569 ! has exposure stimulus nigericin
relationship: RO:0002309 CHEBI:7569 ! has exposure stimulus nigericin

[Term]
id: ECTO:9002514
name: exposure to nigerose
def: "An exposure to nigerose." []
synonym: "nigerose exposure" EXACT []
is_a: ECTO:9000240 ! exposure to disaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7570 ! has exposure stimulus nigerose
relationship: RO:0002309 CHEBI:7570 ! has exposure stimulus nigerose

[Term]
id: ECTO:9002515
name: exposure to nilotinib
def: "An exposure to nilotinib." []
synonym: "nilotinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52172 ! has exposure stimulus nilotinib
relationship: RO:0002309 CHEBI:52172 ! has exposure stimulus nilotinib

[Term]
id: ECTO:9002516
name: exposure to nintedanib
def: "An exposure to nintedanib." []
synonym: "nintedanib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:85164 ! has exposure stimulus nintedanib
relationship: RO:0002309 CHEBI:85164 ! has exposure stimulus nintedanib

[Term]
id: ECTO:9002517
name: exposure to nitisinone
def: "An exposure to nitisinone." []
synonym: "nitisinone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9000668 ! exposure to mesotrione
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50378 ! has exposure stimulus nitisinone
relationship: RO:0002309 CHEBI:50378 ! has exposure stimulus nitisinone

[Term]
id: ECTO:9002518
name: exposure to nitrofurantoin
def: "An exposure to nitrofurantoin." []
synonym: "nitrofurantoin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71415 ! has exposure stimulus nitrofurantoin
relationship: RO:0002309 CHEBI:71415 ! has exposure stimulus nitrofurantoin

[Term]
id: ECTO:9002519
name: exposure to Nivolumab
def: "An exposure to Nivolumab." []
synonym: "Nivolumab exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:231614 ! has exposure stimulus Nivolumab
relationship: RO:0002309 CHEBI:231614 ! has exposure stimulus Nivolumab

[Term]
id: ECTO:9002520
name: exposure to norathyriol
def: "An exposure to norathyriol." []
synonym: "norathyriol exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7622 ! has exposure stimulus norathyriol
relationship: RO:0002309 CHEBI:7622 ! has exposure stimulus norathyriol

[Term]
id: ECTO:9002521
name: exposure to norgestrel
def: "An exposure to norgestrel." []
synonym: "norgestrel exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7630 ! has exposure stimulus norgestrel
relationship: RO:0002309 CHEBI:7630 ! has exposure stimulus norgestrel

[Term]
id: ECTO:9002522
name: exposure to bisabolane
def: "An exposure to bisabolane." []
synonym: "bisabolane exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000199 ! exposure to cycloalkane
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36480 ! has exposure stimulus bisabolane
relationship: RO:0002309 CHEBI:36480 ! has exposure stimulus bisabolane

[Term]
id: ECTO:9002523
name: exposure to nystatin
def: "An exposure to nystatin." []
synonym: "nystatin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002231 ! exposure to aminoglycoside antibiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7660 ! has exposure stimulus nystatin
relationship: RO:0002309 CHEBI:7660 ! has exposure stimulus nystatin

[Term]
id: ECTO:9002524
name: exposure to obeticholic acid
def: "An exposure to obeticholic acid." []
synonym: "obeticholic acid exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43602 ! has exposure stimulus obeticholic acid
relationship: RO:0002309 CHEBI:43602 ! has exposure stimulus obeticholic acid

[Term]
id: ECTO:9002525
name: exposure to octocrylene
def: "An exposure to octocrylene." []
synonym: "octocrylene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:135526 ! has exposure stimulus octocrylene
relationship: RO:0002309 CHEBI:135526 ! has exposure stimulus octocrylene

[Term]
id: ECTO:9002526
name: exposure to oleanolic acid
def: "An exposure to oleanolic acid." []
synonym: "oleanolic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37659 ! has exposure stimulus oleanolic acid
relationship: RO:0002309 CHEBI:37659 ! has exposure stimulus oleanolic acid

[Term]
id: ECTO:9002527
name: exposure to oleic acid
def: "An exposure to oleic acid." []
synonym: "oleic acid exposure" EXACT []
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16196 ! has exposure stimulus oleic acid
relationship: RO:0002309 CHEBI:16196 ! has exposure stimulus oleic acid

[Term]
id: ECTO:9002528
name: exposure to indole-3-carboxylic acid
def: "An exposure to indole-3-carboxylic acid." []
synonym: "indole-3-carboxylic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24809 ! has exposure stimulus indole-3-carboxylic acid
relationship: RO:0002309 CHEBI:24809 ! has exposure stimulus indole-3-carboxylic acid

[Term]
id: ECTO:9002529
name: exposure to N-methylserotonin(1+)
def: "An exposure to N-methylserotonin(1+)." []
synonym: "N-methylserotonin(1+) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000304 ! exposure to ammonium ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:746957 ! has exposure stimulus N-methylserotonin(1+)
relationship: RO:0002309 CHEBI:746957 ! has exposure stimulus N-methylserotonin(1+)

[Term]
id: ECTO:9002530
name: exposure to oxaliplatin
def: "An exposure to oxaliplatin." []
synonym: "oxaliplatin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000949 ! exposure to platinum
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31941 ! has exposure stimulus oxaliplatin
relationship: RO:0002309 CHEBI:31941 ! has exposure stimulus oxaliplatin

[Term]
id: ECTO:9002531
name: exposure to oxcarbazepine
def: "An exposure to oxcarbazepine." []
synonym: "oxcarbazepine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7824 ! has exposure stimulus oxcarbazepine
relationship: RO:0002309 CHEBI:7824 ! has exposure stimulus oxcarbazepine

[Term]
id: ECTO:9002532
name: exposure to glutathione disulfide(2-)
def: "An exposure to glutathione disulfide(2-)." []
synonym: "glutathione disulfide(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:58297 ! has exposure stimulus glutathione disulfide(2-)
relationship: RO:0002309 CHEBI:58297 ! has exposure stimulus glutathione disulfide(2-)

[Term]
id: ECTO:9002533
name: exposure to oxygen-18 atom
def: "An exposure to oxygen-18 atom." []
synonym: "oxygen-18 atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33815 ! has exposure stimulus oxygen-18 atom
relationship: RO:0002309 CHEBI:33815 ! has exposure stimulus oxygen-18 atom

[Term]
id: ECTO:9002534
name: exposure to Oxytetracycline hydrochloride
def: "An exposure to Oxytetracycline hydrochloride." []
synonym: "Oxytetracycline hydrochloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31953 ! has exposure stimulus Oxytetracycline hydrochloride
relationship: RO:0002309 CHEBI:31953 ! has exposure stimulus Oxytetracycline hydrochloride

[Term]
id: ECTO:9002535
name: exposure to p-cresol sulfate(1-)
def: "An exposure to p-cresol sulfate(1-)." []
synonym: "p-cresol sulfate(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:133670 ! has exposure stimulus p-cresol sulfate(1-)
relationship: RO:0002309 CHEBI:133670 ! has exposure stimulus p-cresol sulfate(1-)

[Term]
id: ECTO:9002536
name: exposure to p-hydroxybenzyl alcohol
def: "An exposure to p-hydroxybenzyl alcohol." []
synonym: "p-hydroxybenzyl alcohol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67410 ! has exposure stimulus p-hydroxybenzyl alcohol
relationship: RO:0002309 CHEBI:67410 ! has exposure stimulus p-hydroxybenzyl alcohol

[Term]
id: ECTO:9002537
name: exposure to Paeonol
def: "An exposure to Paeonol." []
synonym: "Paeonol exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:69581 ! has exposure stimulus Paeonol
relationship: RO:0002309 CHEBI:69581 ! has exposure stimulus Paeonol

[Term]
id: ECTO:9002538
name: exposure to paliperidone
def: "An exposure to paliperidone." []
synonym: "paliperidone exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82978 ! has exposure stimulus paliperidone
relationship: RO:0002309 CHEBI:82978 ! has exposure stimulus paliperidone

[Term]
id: ECTO:9002539
name: exposure to paliperidone palmitate
def: "An exposure to paliperidone palmitate." []
synonym: "paliperidone palmitate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83807 ! has exposure stimulus paliperidone palmitate
relationship: RO:0002309 CHEBI:83807 ! has exposure stimulus paliperidone palmitate

[Term]
id: ECTO:9002540
name: exposure to S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys
def: "An exposure to S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys." []
synonym: "S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000402 ! exposure to peptide
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46889 ! has exposure stimulus S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys
relationship: RO:0002309 CHEBI:46889 ! has exposure stimulus S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys

[Term]
id: ECTO:9002541
name: exposure to pantetheine
def: "An exposure to pantetheine." []
synonym: "pantetheine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16753 ! has exposure stimulus pantetheine
relationship: RO:0002309 CHEBI:16753 ! has exposure stimulus pantetheine

[Term]
id: ECTO:9002542
name: exposure to pantethine
def: "An exposure to pantethine." []
synonym: "pantethine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31959 ! has exposure stimulus pantethine
relationship: RO:0002309 CHEBI:31959 ! has exposure stimulus pantethine

[Term]
id: ECTO:9002543
name: exposure to pantothenate
def: "An exposure to pantothenate." []
synonym: "pantothenate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16454 ! has exposure stimulus pantothenate
relationship: RO:0002309 CHEBI:16454 ! has exposure stimulus pantothenate

[Term]
id: ECTO:9002544
name: exposure to paraoxon
def: "An exposure to paraoxon." []
synonym: "paraoxon exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27827 ! has exposure stimulus paraoxon
relationship: RO:0002309 CHEBI:27827 ! has exposure stimulus paraoxon

[Term]
id: ECTO:9002545
name: exposure to paroxetine
def: "An exposure to paroxetine." []
synonym: "paroxetine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7936 ! has exposure stimulus paroxetine
relationship: RO:0002309 CHEBI:7936 ! has exposure stimulus paroxetine

[Term]
id: ECTO:9002546
name: exposure to pazopanib
def: "An exposure to pazopanib." []
synonym: "pazopanib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71219 ! has exposure stimulus pazopanib
relationship: RO:0002309 CHEBI:71219 ! has exposure stimulus pazopanib

[Term]
id: ECTO:9002547
name: exposure to PD 0325901
def: "An exposure to PD 0325901." []
synonym: "PD 0325901 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9002156 ! exposure to glycol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88249 ! has exposure stimulus PD 0325901
relationship: RO:0002309 CHEBI:88249 ! has exposure stimulus PD 0325901

[Term]
id: ECTO:9002548
name: exposure to pemafibrate
def: "An exposure to pemafibrate." []
synonym: "pemafibrate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:228365 ! has exposure stimulus pemafibrate
relationship: RO:0002309 CHEBI:228365 ! has exposure stimulus pemafibrate

[Term]
id: ECTO:9002549
name: exposure to pemetrexed
def: "An exposure to pemetrexed." []
synonym: "pemetrexed exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63616 ! has exposure stimulus pemetrexed
relationship: RO:0002309 CHEBI:63616 ! has exposure stimulus pemetrexed

[Term]
id: ECTO:9002550
name: exposure to benzylpenicillin
def: "An exposure to benzylpenicillin." []
synonym: "benzylpenicillin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18208 ! has exposure stimulus benzylpenicillin
relationship: RO:0002309 CHEBI:18208 ! has exposure stimulus benzylpenicillin

[Term]
id: ECTO:9002551
name: exposure to perillyl aldehyde
def: "An exposure to perillyl aldehyde." []
synonym: "perillyl aldehyde exposure" EXACT []
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15421 ! has exposure stimulus perillyl aldehyde
relationship: RO:0002309 CHEBI:15421 ! has exposure stimulus perillyl aldehyde

[Term]
id: ECTO:9002552
name: exposure to perindopril
def: "An exposure to perindopril." []
synonym: "perindopril exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8024 ! has exposure stimulus perindopril
relationship: RO:0002309 CHEBI:8024 ! has exposure stimulus perindopril

[Term]
id: ECTO:9002553
name: exposure to peroxynitrite
def: "An exposure to peroxynitrite." []
synonym: "peroxynitrite exposure" EXACT []
is_a: ECTO:9000150 ! exposure to reactive oxygen species
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25941 ! has exposure stimulus peroxynitrite
relationship: RO:0002309 CHEBI:25941 ! has exposure stimulus peroxynitrite

[Term]
id: ECTO:9002554
name: exposure to pinacyanol iodide
def: "An exposure to pinacyanol iodide." []
synonym: "pinacyanol iodide exposure" EXACT []
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52218 ! has exposure stimulus pinacyanol iodide
relationship: RO:0002309 CHEBI:52218 ! has exposure stimulus pinacyanol iodide

[Term]
id: ECTO:9002555
name: exposure to pioglitazone
def: "An exposure to pioglitazone." []
synonym: "pioglitazone exposure" EXACT []
is_a: ECTO:9000013 ! exposure to thiazolidinediones
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8228 ! has exposure stimulus pioglitazone
relationship: RO:0002309 CHEBI:8228 ! has exposure stimulus pioglitazone

[Term]
id: ECTO:9002556
name: exposure to pirarubicin
def: "An exposure to pirarubicin." []
synonym: "pirarubicin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9001246 ! exposure to quinone
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9002237 ! exposure to anthracycline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:94770 ! has exposure stimulus pirarubicin
relationship: RO:0002309 CHEBI:94770 ! has exposure stimulus pirarubicin

[Term]
id: ECTO:9002557
name: exposure to PLX5622
def: "An exposure to PLX5622." []
synonym: "PLX5622 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:230497 ! has exposure stimulus PLX5622
relationship: RO:0002309 CHEBI:230497 ! has exposure stimulus PLX5622

[Term]
id: ECTO:9002558
name: exposure to polyamine
def: "An exposure to polyamine." []
synonym: "polyamine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:88061 ! has exposure stimulus polyamine
relationship: RO:0002309 CHEBI:88061 ! has exposure stimulus polyamine

[Term]
id: ECTO:9002559
name: exposure to poly(ethylene terephthalate) polymer
def: "An exposure to poly(ethylene terephthalate) polymer." []
synonym: "poly(ethylene terephthalate) polymer exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:61452 ! has exposure stimulus poly(ethylene terephthalate) polymer
relationship: RO:0002309 CHEBI:61452 ! has exposure stimulus poly(ethylene terephthalate) polymer

[Term]
id: ECTO:9002560
name: exposure to poly(lactic acid) polymer
def: "An exposure to poly(lactic acid) polymer." []
synonym: "poly(lactic acid) polymer exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:60159 ! has exposure stimulus poly(lactic acid) polymer
relationship: RO:0002309 CHEBI:60159 ! has exposure stimulus poly(lactic acid) polymer

[Term]
id: ECTO:9002561
name: exposure to polymyxin
def: "An exposure to polymyxin." []
synonym: "polymyxin exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59062 ! has exposure stimulus polymyxin
relationship: RO:0002309 CHEBI:59062 ! has exposure stimulus polymyxin

[Term]
id: ECTO:9002562
name: exposure to polyphenol
def: "An exposure to polyphenol." []
synonym: "polyphenol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26195 ! has exposure stimulus polyphenol
relationship: RO:0002309 CHEBI:26195 ! has exposure stimulus polyphenol

[Term]
id: ECTO:9002563
name: exposure to polystyrene macromolecule
def: "An exposure to polystyrene macromolecule." []
synonym: "polystyrene macromolecule exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53270 ! has exposure stimulus polystyrene macromolecule
relationship: RO:0002309 CHEBI:53270 ! has exposure stimulus polystyrene macromolecule

[Term]
id: ECTO:9002564
name: exposure to poly(sulfide) macromolecule
def: "An exposure to poly(sulfide) macromolecule." []
synonym: "poly(sulfide) macromolecule exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53720 ! has exposure stimulus poly(sulfide) macromolecule
relationship: RO:0002309 CHEBI:53720 ! has exposure stimulus poly(sulfide) macromolecule

[Term]
id: ECTO:9002565
name: exposure to oligosaccharide
def: "An exposure to oligosaccharide." []
synonym: "oligosaccharide exposure" EXACT []
is_a: ECTO:9000162 ! exposure to carbohydrate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50699 ! has exposure stimulus oligosaccharide
relationship: RO:0002309 CHEBI:50699 ! has exposure stimulus oligosaccharide

[Term]
id: ECTO:9002566
name: exposure to pyrimidine-2,4-diamine
def: "An exposure to pyrimidine-2,4-diamine." []
synonym: "pyrimidine-2,4-diamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43745 ! has exposure stimulus pyrimidine-2,4-diamine
relationship: RO:0002309 CHEBI:43745 ! has exposure stimulus pyrimidine-2,4-diamine

[Term]
id: ECTO:9002567
name: exposure to primaquine
def: "An exposure to primaquine." []
synonym: "primaquine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8405 ! has exposure stimulus primaquine
relationship: RO:0002309 CHEBI:8405 ! has exposure stimulus primaquine

[Term]
id: ECTO:9002568
name: exposure to L-proline
def: "An exposure to L-proline." []
synonym: "L-proline exposure" EXACT []
is_a: ECTO:9000189 ! exposure to proline
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17203 ! has exposure stimulus L-proline
relationship: RO:0002309 CHEBI:17203 ! has exposure stimulus L-proline

[Term]
id: ECTO:9002569
name: exposure to endocannabinoid
def: "An exposure to endocannabinoid." []
synonym: "endocannabinoid exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67197 ! has exposure stimulus endocannabinoid
relationship: RO:0002309 CHEBI:67197 ! has exposure stimulus endocannabinoid

[Term]
id: ECTO:9002570
name: exposure to propionate
def: "An exposure to propionate." []
synonym: "propionate exposure" EXACT []
is_a: ECTO:9002589 ! exposure to saturated fatty acid anion
is_a: ECTO:9002596 ! exposure to short-chain fatty acid anion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17272 ! has exposure stimulus propionate
relationship: RO:0002309 CHEBI:17272 ! has exposure stimulus propionate

[Term]
id: ECTO:9002571
name: exposure to propofol
def: "An exposure to propofol." []
synonym: "propofol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44915 ! has exposure stimulus propofol
relationship: RO:0002309 CHEBI:44915 ! has exposure stimulus propofol

[Term]
id: ECTO:9002572
name: exposure to propranolol hydrochloride
def: "An exposure to propranolol hydrochloride." []
synonym: "propranolol hydrochloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8500 ! has exposure stimulus propranolol hydrochloride
relationship: RO:0002309 CHEBI:8500 ! has exposure stimulus propranolol hydrochloride

[Term]
id: ECTO:9002573
name: exposure to psora 4
def: "An exposure to psora 4." []
synonym: "psora 4 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:183514 ! has exposure stimulus psora 4
relationship: RO:0002309 CHEBI:183514 ! has exposure stimulus psora 4

[Term]
id: ECTO:9002574
name: exposure to Pyrazolopyrimidinone
def: "An exposure to Pyrazolopyrimidinone." []
synonym: "Pyrazolopyrimidinone exposure" EXACT []
is_a: ECTO:9002871 ! exposure to pyrazolopyrimidine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:231209 ! has exposure stimulus Pyrazolopyrimidinone
relationship: RO:0002309 CHEBI:231209 ! has exposure stimulus Pyrazolopyrimidinone

[Term]
id: ECTO:9002575
name: exposure to Pyridostigmine bromide
def: "An exposure to Pyridostigmine bromide." []
synonym: "Pyridostigmine bromide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8666 ! has exposure stimulus Pyridostigmine bromide
relationship: RO:0002309 CHEBI:8666 ! has exposure stimulus Pyridostigmine bromide

[Term]
id: ECTO:9002576
name: exposure to pyriproxyfen
def: "An exposure to pyriproxyfen." []
synonym: "pyriproxyfen exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:39260 ! has exposure stimulus pyriproxyfen
relationship: RO:0002309 CHEBI:39260 ! has exposure stimulus pyriproxyfen

[Term]
id: ECTO:9002577
name: exposure to pyrrolizidine alkaloid
def: "An exposure to pyrrolizidine alkaloid." []
synonym: "pyrrolizidine alkaloid exposure" EXACT []
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64948 ! has exposure stimulus pyrrolizidine alkaloid
relationship: RO:0002309 CHEBI:64948 ! has exposure stimulus pyrrolizidine alkaloid

[Term]
id: ECTO:9002578
name: exposure to pyruvate
def: "An exposure to pyruvate." []
synonym: "pyruvate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15361 ! has exposure stimulus pyruvate
relationship: RO:0002309 CHEBI:15361 ! has exposure stimulus pyruvate

[Term]
id: ECTO:9002579
name: exposure to quinic acid
def: "An exposure to quinic acid." []
synonym: "quinic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26493 ! has exposure stimulus quinic acid
relationship: RO:0002309 CHEBI:26493 ! has exposure stimulus quinic acid

[Term]
id: ECTO:9002580
name: exposure to ractopamine
def: "An exposure to ractopamine." []
synonym: "ractopamine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82644 ! has exposure stimulus ractopamine
relationship: RO:0002309 CHEBI:82644 ! has exposure stimulus ractopamine

[Term]
id: ECTO:9002581
name: exposure to Ramatroban
def: "An exposure to Ramatroban." []
synonym: "Ramatroban exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32087 ! has exposure stimulus Ramatroban
relationship: RO:0002309 CHEBI:32087 ! has exposure stimulus Ramatroban

[Term]
id: ECTO:9002582
name: exposure to remdesivir
def: "An exposure to remdesivir." []
synonym: "remdesivir exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9001227 ! exposure to phosphorus
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:145994 ! has exposure stimulus remdesivir
relationship: RO:0002309 CHEBI:145994 ! has exposure stimulus remdesivir

[Term]
id: ECTO:9002583
name: exposure to 4-(4-Hydroxyphenyl)-2-butanol
def: "An exposure to 4-(4-Hydroxyphenyl)-2-butanol." []
synonym: "4-(4-Hydroxyphenyl)-2-butanol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81278 ! has exposure stimulus 4-(4-Hydroxyphenyl)-2-butanol
relationship: RO:0002309 CHEBI:81278 ! has exposure stimulus 4-(4-Hydroxyphenyl)-2-butanol

[Term]
id: ECTO:9002584
name: exposure to rifampicin
def: "An exposure to rifampicin." []
synonym: "rifampicin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28077 ! has exposure stimulus rifampicin
relationship: RO:0002309 CHEBI:28077 ! has exposure stimulus rifampicin

[Term]
id: ECTO:9002585
name: exposure to rocuronium
def: "An exposure to rocuronium." []
synonym: "rocuronium exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000304 ! exposure to ammonium ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8884 ! has exposure stimulus rocuronium
relationship: RO:0002309 CHEBI:8884 ! has exposure stimulus rocuronium

[Term]
id: ECTO:9002586
name: exposure to rose bengal
def: "An exposure to rose bengal." []
synonym: "rose bengal exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:52261 ! has exposure stimulus rose bengal
relationship: RO:0002309 CHEBI:52261 ! has exposure stimulus rose bengal

[Term]
id: ECTO:9002587
name: exposure to S-methyl methanethiosulfonate
def: "An exposure to S-methyl methanethiosulfonate." []
synonym: "S-methyl methanethiosulfonate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74357 ! has exposure stimulus S-methyl methanethiosulfonate
relationship: RO:0002309 CHEBI:74357 ! has exposure stimulus S-methyl methanethiosulfonate

[Term]
id: ECTO:9002588
name: exposure to Salidroside
def: "An exposure to Salidroside." []
synonym: "Salidroside exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9009 ! has exposure stimulus Salidroside
relationship: RO:0002309 CHEBI:9009 ! has exposure stimulus Salidroside

[Term]
id: ECTO:9002589
name: exposure to saturated fatty acid anion
def: "An exposure to saturated fatty acid anion." []
synonym: "saturated fatty acid anion exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:58953 ! has exposure stimulus saturated fatty acid anion
relationship: RO:0002309 CHEBI:58953 ! has exposure stimulus saturated fatty acid anion

[Term]
id: ECTO:9002590
name: exposure to Secosterol-A
def: "An exposure to Secosterol-A." []
synonym: "Secosterol-A exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:166812 ! has exposure stimulus Secosterol-A
relationship: RO:0002309 CHEBI:166812 ! has exposure stimulus Secosterol-A

[Term]
id: ECTO:9002591
name: exposure to selenium atom
def: "An exposure to selenium atom." []
synonym: "selenium atom exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27568 ! has exposure stimulus selenium atom
relationship: RO:0002309 CHEBI:27568 ! has exposure stimulus selenium atom

[Term]
id: ECTO:9002592
name: exposure to selenocystine
def: "An exposure to selenocystine." []
synonym: "selenocystine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000950 ! exposure to selenium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28553 ! has exposure stimulus selenocystine
relationship: RO:0002309 CHEBI:28553 ! has exposure stimulus selenocystine

[Term]
id: ECTO:9002593
name: exposure to sertraline
def: "An exposure to sertraline." []
synonym: "sertraline exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9123 ! has exposure stimulus sertraline
relationship: RO:0002309 CHEBI:9123 ! has exposure stimulus sertraline

[Term]
id: ECTO:9002594
name: exposure to sertraline hydrochloride
def: "An exposure to sertraline hydrochloride." []
synonym: "sertraline hydrochloride exposure" EXACT []
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9124 ! has exposure stimulus sertraline hydrochloride
relationship: RO:0002309 CHEBI:9124 ! has exposure stimulus sertraline hydrochloride

[Term]
id: ECTO:9002595
name: exposure to Shikonin
def: "An exposure to Shikonin." []
synonym: "Shikonin exposure" EXACT []
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81068 ! has exposure stimulus Shikonin
relationship: RO:0002309 CHEBI:81068 ! has exposure stimulus Shikonin

[Term]
id: ECTO:9002596
name: exposure to short-chain fatty acid anion
def: "An exposure to short-chain fatty acid anion." []
synonym: "short-chain fatty acid anion exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:58951 ! has exposure stimulus short-chain fatty acid anion
relationship: RO:0002309 CHEBI:58951 ! has exposure stimulus short-chain fatty acid anion

[Term]
id: ECTO:9002597
name: exposure to sildenafil citrate
def: "An exposure to sildenafil citrate." []
synonym: "sildenafil citrate exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:58987 ! has exposure stimulus sildenafil citrate
relationship: RO:0002309 CHEBI:58987 ! has exposure stimulus sildenafil citrate

[Term]
id: ECTO:9002598
name: exposure to silver nanoparticle
def: "An exposure to silver nanoparticle." []
synonym: "silver nanoparticle exposure" EXACT []
is_a: ECTO:9001252 ! exposure to elemental silver
is_a: ECTO:9002233 ! exposure to nanoparticle
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50826 ! has exposure stimulus silver nanoparticle
relationship: RO:0002309 CHEBI:50826 ! has exposure stimulus silver nanoparticle

[Term]
id: ECTO:9002599
name: exposure to silver(1+) nitrate
def: "An exposure to silver(1+) nitrate." []
synonym: "silver(1+) nitrate exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000409 ! exposure to salt
is_a: ECTO:9001311 ! exposure to silver
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32130 ! has exposure stimulus silver(1+) nitrate
relationship: RO:0002309 CHEBI:32130 ! has exposure stimulus silver(1+) nitrate

[Term]
id: ECTO:9002600
name: exposure to sinefungin
def: "An exposure to sinefungin." []
synonym: "sinefungin exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45453 ! has exposure stimulus sinefungin
relationship: RO:0002309 CHEBI:45453 ! has exposure stimulus sinefungin

[Term]
id: ECTO:9002601
name: exposure to sodium acetate
def: "An exposure to sodium acetate." []
synonym: "sodium acetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32954 ! has exposure stimulus sodium acetate
relationship: RO:0002309 CHEBI:32954 ! has exposure stimulus sodium acetate

[Term]
id: ECTO:9002602
name: exposure to sodium butyrate
def: "An exposure to sodium butyrate." []
synonym: "sodium butyrate exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64103 ! has exposure stimulus sodium butyrate
relationship: RO:0002309 CHEBI:64103 ! has exposure stimulus sodium butyrate

[Term]
id: ECTO:9002603
name: exposure to sodium glyoxylate
def: "An exposure to sodium glyoxylate." []
synonym: "sodium glyoxylate exposure" EXACT []
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:91251 ! has exposure stimulus sodium glyoxylate
relationship: RO:0002309 CHEBI:91251 ! has exposure stimulus sodium glyoxylate

[Term]
id: ECTO:9002604
name: exposure to pentobarbital
def: "An exposure to pentobarbital." []
synonym: "pentobarbital exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7983 ! has exposure stimulus pentobarbital
relationship: RO:0002309 CHEBI:7983 ! has exposure stimulus pentobarbital

[Term]
id: ECTO:9002605
name: exposure to sodium propionate
def: "An exposure to sodium propionate." []
synonym: "sodium propionate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132106 ! has exposure stimulus sodium propionate
relationship: RO:0002309 CHEBI:132106 ! has exposure stimulus sodium propionate

[Term]
id: ECTO:9002606
name: exposure to sodium pyruvate
def: "An exposure to sodium pyruvate." []
synonym: "sodium pyruvate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50144 ! has exposure stimulus sodium pyruvate
relationship: RO:0002309 CHEBI:50144 ! has exposure stimulus sodium pyruvate

[Term]
id: ECTO:9002607
name: exposure to sodium valproate
def: "An exposure to sodium valproate." []
synonym: "sodium valproate exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9925 ! has exposure stimulus sodium valproate
relationship: RO:0002309 CHEBI:9925 ! has exposure stimulus sodium valproate

[Term]
id: ECTO:9002608
name: exposure to sorafenib
def: "An exposure to sorafenib." []
synonym: "sorafenib exposure" EXACT []
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50924 ! has exposure stimulus sorafenib
relationship: RO:0002309 CHEBI:50924 ! has exposure stimulus sorafenib

[Term]
id: ECTO:9002609
name: exposure to sorafenib tosylate
def: "An exposure to sorafenib tosylate." []
synonym: "sorafenib tosylate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50928 ! has exposure stimulus sorafenib tosylate
relationship: RO:0002309 CHEBI:50928 ! has exposure stimulus sorafenib tosylate

[Term]
id: ECTO:9002610
name: exposure to spermidine
def: "An exposure to spermidine." []
synonym: "spermidine exposure" EXACT []
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16610 ! has exposure stimulus spermidine
relationship: RO:0002309 CHEBI:16610 ! has exposure stimulus spermidine

[Term]
id: ECTO:9002611
name: exposure to spermine
def: "An exposure to spermine." []
synonym: "spermine exposure" EXACT []
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15746 ! has exposure stimulus spermine
relationship: RO:0002309 CHEBI:15746 ! has exposure stimulus spermine

[Term]
id: ECTO:9002612
name: exposure to sphingosine
def: "An exposure to sphingosine." []
synonym: "sphingosine exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16393 ! has exposure stimulus sphingosine
relationship: RO:0002309 CHEBI:16393 ! has exposure stimulus sphingosine

[Term]
id: ECTO:9002613
name: exposure to D-mannitol
def: "An exposure to D-mannitol." []
synonym: "D-mannitol exposure" EXACT []
is_a: ECTO:9000197 ! exposure to mannitol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16899 ! has exposure stimulus D-mannitol
relationship: RO:0002309 CHEBI:16899 ! has exposure stimulus D-mannitol

[Term]
id: ECTO:9002614
name: exposure to stavudine
def: "An exposure to stavudine." []
synonym: "stavudine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63581 ! has exposure stimulus stavudine
relationship: RO:0002309 CHEBI:63581 ! has exposure stimulus stavudine

[Term]
id: ECTO:9002615
name: exposure to strontium(2+)
def: "An exposure to strontium(2+)." []
synonym: "strontium(2+) exposure" EXACT []
is_a: ECTO:9000175 ! exposure to metal cation
is_a: ECTO:9000951 ! exposure to strontium
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35104 ! has exposure stimulus strontium(2+)
relationship: RO:0002309 CHEBI:35104 ! has exposure stimulus strontium(2+)

[Term]
id: ECTO:9002616
name: exposure to strontium atom
def: "An exposure to strontium atom." []
synonym: "strontium atom exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33324 ! has exposure stimulus strontium atom
relationship: RO:0002309 CHEBI:33324 ! has exposure stimulus strontium atom

[Term]
id: ECTO:9002617
name: exposure to substance P
def: "An exposure to substance P." []
synonym: "substance P exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80308 ! has exposure stimulus substance P
relationship: RO:0002309 CHEBI:80308 ! has exposure stimulus substance P

[Term]
id: ECTO:9002618
name: exposure to succinic acid
def: "An exposure to succinic acid." []
synonym: "succinic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15741 ! has exposure stimulus succinic acid
relationship: RO:0002309 CHEBI:15741 ! has exposure stimulus succinic acid

[Term]
id: ECTO:9002619
name: exposure to sulfate
def: "An exposure to sulfate." []
synonym: "sulfate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16189 ! has exposure stimulus sulfate
relationship: RO:0002309 CHEBI:16189 ! has exposure stimulus sulfate

[Term]
id: ECTO:9002620
name: exposure to sulforaphane
def: "An exposure to sulforaphane." []
synonym: "sulforaphane exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47807 ! has exposure stimulus sulforaphane
relationship: RO:0002309 CHEBI:47807 ! has exposure stimulus sulforaphane

[Term]
id: ECTO:9002621
name: exposure to sulfoxaflor
def: "An exposure to sulfoxaflor." []
synonym: "sulfoxaflor exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:133305 ! has exposure stimulus sulfoxaflor
relationship: RO:0002309 CHEBI:133305 ! has exposure stimulus sulfoxaflor

[Term]
id: ECTO:9002622
name: exposure to sunitinib
def: "An exposure to sunitinib." []
synonym: "sunitinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38940 ! has exposure stimulus sunitinib
relationship: RO:0002309 CHEBI:38940 ! has exposure stimulus sunitinib

[Term]
id: ECTO:9002623
name: exposure to iron oxide
def: "An exposure to iron oxide." []
synonym: "iron oxide exposure" EXACT []
is_a: ECTO:9000087 ! exposure to iron
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50816 ! has exposure stimulus iron oxide
relationship: RO:0002309 CHEBI:50816 ! has exposure stimulus iron oxide

[Term]
id: ECTO:9002624
name: exposure to suramin
def: "An exposure to suramin." []
synonym: "suramin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001541 ! exposure to phenylureas
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45906 ! has exposure stimulus suramin
relationship: RO:0002309 CHEBI:45906 ! has exposure stimulus suramin

[Term]
id: ECTO:9002625
name: exposure to taurine
def: "An exposure to taurine." []
synonym: "taurine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15891 ! has exposure stimulus taurine
relationship: RO:0002309 CHEBI:15891 ! has exposure stimulus taurine

[Term]
id: ECTO:9002626
name: exposure to taurochenodeoxycholic acid
def: "An exposure to taurochenodeoxycholic acid." []
synonym: "taurochenodeoxycholic acid exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16525 ! has exposure stimulus taurochenodeoxycholic acid
relationship: RO:0002309 CHEBI:16525 ! has exposure stimulus taurochenodeoxycholic acid

[Term]
id: ECTO:9002627
name: exposure to taxane diterpenoid
def: "An exposure to taxane diterpenoid." []
synonym: "taxane diterpenoid exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50367 ! has exposure stimulus taxane diterpenoid
relationship: RO:0002309 CHEBI:50367 ! has exposure stimulus taxane diterpenoid

[Term]
id: ECTO:9002628
name: exposure to taxane
def: "An exposure to taxane." []
synonym: "taxane exposure" EXACT []
is_a: ECTO:9000494 ! exposure to diterpene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36064 ! has exposure stimulus taxane
relationship: RO:0002309 CHEBI:36064 ! has exposure stimulus taxane

[Term]
id: ECTO:9002629
name: exposure to tebufenpyrad
def: "An exposure to tebufenpyrad." []
synonym: "tebufenpyrad exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9422 ! has exposure stimulus tebufenpyrad
relationship: RO:0002309 CHEBI:9422 ! has exposure stimulus tebufenpyrad

[Term]
id: ECTO:9002630
name: exposure to tenofovir disoproxil fumarate
def: "An exposure to tenofovir disoproxil fumarate." []
synonym: "tenofovir disoproxil fumarate exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63718 ! has exposure stimulus tenofovir disoproxil fumarate
relationship: RO:0002309 CHEBI:63718 ! has exposure stimulus tenofovir disoproxil fumarate

[Term]
id: ECTO:9002631
name: exposure to terbinafine
def: "An exposure to terbinafine." []
synonym: "terbinafine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9448 ! has exposure stimulus terbinafine
relationship: RO:0002309 CHEBI:9448 ! has exposure stimulus terbinafine

[Term]
id: ECTO:9002632
name: exposure to terephthalate(2-)
def: "An exposure to terephthalate(2-)." []
synonym: "terephthalate(2-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30043 ! has exposure stimulus terephthalate(2-)
relationship: RO:0002309 CHEBI:30043 ! has exposure stimulus terephthalate(2-)

[Term]
id: ECTO:9002633
name: exposure to terephthalic acid
def: "An exposure to terephthalic acid." []
synonym: "terephthalic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15702 ! has exposure stimulus terephthalic acid
relationship: RO:0002309 CHEBI:15702 ! has exposure stimulus terephthalic acid

[Term]
id: ECTO:9002634
name: exposure to 2-(tetradecylthio)acetic acid
def: "An exposure to 2-(tetradecylthio)acetic acid." []
synonym: "2-(tetradecylthio)acetic acid exposure" EXACT []
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:94633 ! has exposure stimulus 2-(tetradecylthio)acetic acid
relationship: RO:0002309 CHEBI:94633 ! has exposure stimulus 2-(tetradecylthio)acetic acid

[Term]
id: ECTO:9002635
name: exposure to thiazide
def: "An exposure to thiazide." []
synonym: "thiazide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50264 ! has exposure stimulus thiazide
relationship: RO:0002309 CHEBI:50264 ! has exposure stimulus thiazide

[Term]
id: ECTO:9002636
name: exposure to azathioprine
def: "An exposure to azathioprine." []
synonym: "azathioprine exposure" EXACT []
is_a: ECTO:9002637 ! exposure to thiopurine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2948 ! has exposure stimulus azathioprine
relationship: RO:0002309 CHEBI:2948 ! has exposure stimulus azathioprine

[Term]
id: ECTO:9002637
name: exposure to thiopurine
def: "An exposure to thiopurine." []
synonym: "thiopurine exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35666 ! has exposure stimulus thiopurine
relationship: RO:0002309 CHEBI:35666 ! has exposure stimulus thiopurine

[Term]
id: ECTO:9002638
name: exposure to thioridazine
def: "An exposure to thioridazine." []
synonym: "thioridazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9566 ! has exposure stimulus thioridazine
relationship: RO:0002309 CHEBI:9566 ! has exposure stimulus thioridazine

[Term]
id: ECTO:9002639
name: exposure to thiouracil
def: "An exposure to thiouracil." []
synonym: "thiouracil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:348530 ! has exposure stimulus thiouracil
relationship: RO:0002309 CHEBI:348530 ! has exposure stimulus thiouracil

[Term]
id: ECTO:9002640
name: exposure to thymol
def: "An exposure to thymol." []
synonym: "thymol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27607 ! has exposure stimulus thymol
relationship: RO:0002309 CHEBI:27607 ! has exposure stimulus thymol

[Term]
id: ECTO:9002641
name: exposure to tigecycline
def: "An exposure to tigecycline." []
synonym: "tigecycline exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:149836 ! has exposure stimulus tigecycline
relationship: RO:0002309 CHEBI:149836 ! has exposure stimulus tigecycline

[Term]
id: ECTO:9002642
name: exposure to mevalonate
def: "An exposure to mevalonate." []
synonym: "mevalonate exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25350 ! has exposure stimulus mevalonate
relationship: RO:0002309 CHEBI:25350 ! has exposure stimulus mevalonate

[Term]
id: ECTO:9002643
name: exposure to tirapazamine
def: "An exposure to tirapazamine." []
synonym: "tirapazamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78887 ! has exposure stimulus tirapazamine
relationship: RO:0002309 CHEBI:78887 ! has exposure stimulus tirapazamine

[Term]
id: ECTO:9002644
name: exposure to tobramycin
def: "An exposure to tobramycin." []
synonym: "tobramycin exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28864 ! has exposure stimulus tobramycin
relationship: RO:0002309 CHEBI:28864 ! has exposure stimulus tobramycin

[Term]
id: ECTO:9002645
name: exposure to tofacitinib
def: "An exposure to tofacitinib." []
synonym: "tofacitinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71200 ! has exposure stimulus tofacitinib
relationship: RO:0002309 CHEBI:71200 ! has exposure stimulus tofacitinib

[Term]
id: ECTO:9002646
name: exposure to tolvaptan
def: "An exposure to tolvaptan." []
synonym: "tolvaptan exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32246 ! has exposure stimulus tolvaptan
relationship: RO:0002309 CHEBI:32246 ! has exposure stimulus tolvaptan

[Term]
id: ECTO:9002647
name: exposure to topotecan
def: "An exposure to topotecan." []
synonym: "topotecan exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63632 ! has exposure stimulus topotecan
relationship: RO:0002309 CHEBI:63632 ! has exposure stimulus topotecan

[Term]
id: ECTO:9002648
name: exposure to trastuzumab
def: "An exposure to trastuzumab." []
synonym: "trastuzumab exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:231601 ! has exposure stimulus trastuzumab
relationship: RO:0002309 CHEBI:231601 ! has exposure stimulus trastuzumab

[Term]
id: ECTO:9002649
name: exposure to Trenbolone acetate
def: "An exposure to Trenbolone acetate." []
synonym: "Trenbolone acetate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:192671 ! has exposure stimulus Trenbolone acetate
relationship: RO:0002309 CHEBI:192671 ! has exposure stimulus Trenbolone acetate

[Term]
id: ECTO:9002650
name: exposure to triacsin C
def: "An exposure to triacsin C." []
synonym: "triacsin C exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:144441 ! has exposure stimulus triacsin C
relationship: RO:0002309 CHEBI:144441 ! has exposure stimulus triacsin C

[Term]
id: ECTO:9002651
name: exposure to trimethylamine N-oxide
def: "An exposure to trimethylamine N-oxide." []
synonym: "trimethylamine N-oxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15724 ! has exposure stimulus trimethylamine N-oxide
relationship: RO:0002309 CHEBI:15724 ! has exposure stimulus trimethylamine N-oxide

[Term]
id: ECTO:9002652
name: exposure to Triptolide
def: "An exposure to Triptolide." []
synonym: "Triptolide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9747 ! has exposure stimulus Triptolide
relationship: RO:0002309 CHEBI:9747 ! has exposure stimulus Triptolide

[Term]
id: ECTO:9002653
name: exposure to tris(1,3-dichloropropan-2-yl) phosphate
def: "An exposure to tris(1,3-dichloropropan-2-yl) phosphate." []
synonym: "tris(1,3-dichloropropan-2-yl) phosphate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:143729 ! has exposure stimulus tris(1,3-dichloropropan-2-yl) phosphate
relationship: RO:0002309 CHEBI:143729 ! has exposure stimulus tris(1,3-dichloropropan-2-yl) phosphate

[Term]
id: ECTO:9002654
name: exposure to uridine 5'-monophosphate(2-)
def: "An exposure to uridine 5'-monophosphate(2-)." []
synonym: "uridine 5'-monophosphate(2-) exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002338 ! exposure to nucleotide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:57865 ! has exposure stimulus uridine 5'-monophosphate(2-)
relationship: RO:0002309 CHEBI:57865 ! has exposure stimulus uridine 5'-monophosphate(2-)

[Term]
id: ECTO:9002655
name: exposure to ursodeoxycholic acid
def: "An exposure to ursodeoxycholic acid." []
synonym: "ursodeoxycholic acid exposure" EXACT []
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9907 ! has exposure stimulus ursodeoxycholic acid
relationship: RO:0002309 CHEBI:9907 ! has exposure stimulus ursodeoxycholic acid

[Term]
id: ECTO:9002656
name: exposure to vancomycin
def: "An exposure to vancomycin." []
synonym: "vancomycin exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28001 ! has exposure stimulus vancomycin
relationship: RO:0002309 CHEBI:28001 ! has exposure stimulus vancomycin

[Term]
id: ECTO:9002657
name: exposure to vandetanib
def: "An exposure to vandetanib." []
synonym: "vandetanib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49960 ! has exposure stimulus vandetanib
relationship: RO:0002309 CHEBI:49960 ! has exposure stimulus vandetanib

[Term]
id: ECTO:9002658
name: exposure to vanillate
def: "An exposure to vanillate." []
synonym: "vanillate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16632 ! has exposure stimulus vanillate
relationship: RO:0002309 CHEBI:16632 ! has exposure stimulus vanillate

[Term]
id: ECTO:9002659
name: exposure to vanillin
def: "An exposure to vanillin." []
synonym: "vanillin exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
is_a: ECTO:9002168 ! exposure to aldehyde
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18346 ! has exposure stimulus vanillin
relationship: RO:0002309 CHEBI:18346 ! has exposure stimulus vanillin

[Term]
id: ECTO:9002660
name: exposure to veliparib
def: "An exposure to veliparib." []
synonym: "veliparib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62880 ! has exposure stimulus veliparib
relationship: RO:0002309 CHEBI:62880 ! has exposure stimulus veliparib

[Term]
id: ECTO:9002661
name: exposure to vemurafenib
def: "An exposure to vemurafenib." []
synonym: "vemurafenib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63637 ! has exposure stimulus vemurafenib
relationship: RO:0002309 CHEBI:63637 ! has exposure stimulus vemurafenib

[Term]
id: ECTO:9002662
name: exposure to vincristine
def: "An exposure to vincristine." []
synonym: "vincristine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28445 ! has exposure stimulus vincristine
relationship: RO:0002309 CHEBI:28445 ! has exposure stimulus vincristine

[Term]
id: ECTO:9002663
name: exposure to vincristine sulfate
def: "An exposure to vincristine sulfate." []
synonym: "vincristine sulfate exposure" EXACT []
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:79401 ! has exposure stimulus vincristine sulfate
relationship: RO:0002309 CHEBI:79401 ! has exposure stimulus vincristine sulfate

[Term]
id: ECTO:9002664
name: exposure to vinorelbine
def: "An exposure to vinorelbine." []
synonym: "vinorelbine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:480999 ! has exposure stimulus vinorelbine
relationship: RO:0002309 CHEBI:480999 ! has exposure stimulus vinorelbine

[Term]
id: ECTO:9002665
name: exposure to voriconazole
def: "An exposure to voriconazole." []
synonym: "voriconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10023 ! has exposure stimulus voriconazole
relationship: RO:0002309 CHEBI:10023 ! has exposure stimulus voriconazole

[Term]
id: ECTO:9002666
name: exposure to VX nerve agent
def: "An exposure to VX nerve agent." []
synonym: "VX nerve agent exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:136185 ! has exposure stimulus VX nerve agent
relationship: RO:0002309 CHEBI:136185 ! has exposure stimulus VX nerve agent

[Term]
id: ECTO:9002667
name: exposure to zearalenone
def: "An exposure to zearalenone." []
synonym: "zearalenone exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10106 ! has exposure stimulus zearalenone
relationship: RO:0002309 CHEBI:10106 ! has exposure stimulus zearalenone

[Term]
id: ECTO:9002668
name: exposure to zinc(2+)
def: "An exposure to zinc(2+)." []
synonym: "zinc(2+) exposure" EXACT []
is_a: ECTO:9000180 ! exposure to zinc cation
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:29105 ! has exposure stimulus zinc(2+)
relationship: RO:0002309 CHEBI:29105 ! has exposure stimulus zinc(2+)

[Term]
id: ECTO:9002669
name: exposure to alpha-pyrrolidinobutiophenone
def: "An exposure to alpha-pyrrolidinobutiophenone." []
synonym: "alpha-pyrrolidinobutiophenone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:197435 ! has exposure stimulus alpha-pyrrolidinobutiophenone
relationship: RO:0002309 CHEBI:197435 ! has exposure stimulus alpha-pyrrolidinobutiophenone

[Term]
id: ECTO:9002670
name: exposure to 17beta-estradiol
def: "An exposure to 17beta-estradiol." []
synonym: "17beta-estradiol exposure" EXACT []
is_a: ECTO:9000212 ! exposure to estradiol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16469 ! has exposure stimulus 17beta-estradiol
relationship: RO:0002309 CHEBI:16469 ! has exposure stimulus 17beta-estradiol

[Term]
id: ECTO:9002671
name: exposure to beta-ocimene
def: "An exposure to beta-ocimene." []
synonym: "beta-ocimene exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10436 ! has exposure stimulus beta-ocimene
relationship: RO:0002309 CHEBI:10436 ! has exposure stimulus beta-ocimene

[Term]
id: ECTO:9002672
name: exposure to gamma-glutamyl-beta-cyanoalanine
def: "An exposure to gamma-glutamyl-beta-cyanoalanine." []
synonym: "gamma-glutamyl-beta-cyanoalanine exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10565 ! has exposure stimulus gamma-glutamyl-beta-cyanoalanine
relationship: RO:0002309 CHEBI:10565 ! has exposure stimulus gamma-glutamyl-beta-cyanoalanine

[Term]
id: ECTO:9002673
name: exposure to 1,4-Methylimidazoleacetic acid
def: "An exposure to 1,4-Methylimidazoleacetic acid." []
synonym: "1,4-Methylimidazoleacetic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:185646 ! has exposure stimulus 1,4-Methylimidazoleacetic acid
relationship: RO:0002309 CHEBI:185646 ! has exposure stimulus 1,4-Methylimidazoleacetic acid

[Term]
id: ECTO:9002674
name: exposure to arsenic(3+)
def: "An exposure to arsenic(3+)." []
synonym: "arsenic(3+) exposure" EXACT []
is_a: ECTO:9000032 ! exposure to arsenic
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35828 ! has exposure stimulus arsenic(3+)
relationship: RO:0002309 CHEBI:35828 ! has exposure stimulus arsenic(3+)

[Term]
id: ECTO:9002675
name: exposure to berberine alkaloid
def: "An exposure to berberine alkaloid." []
synonym: "berberine alkaloid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000200 ! exposure to isoquinoline alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22754 ! has exposure stimulus berberine alkaloid
relationship: RO:0002309 CHEBI:22754 ! has exposure stimulus berberine alkaloid

[Term]
id: ECTO:9002676
name: exposure to CHIR 99021
def: "An exposure to CHIR 99021." []
synonym: "CHIR 99021 exposure" EXACT []
is_a: ECTO:9000058 ! exposure to dichlorobenzene
is_a: ECTO:9002139 ! exposure to nitrile
is_a: ECTO:9002558 ! exposure to polyamine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:91091 ! has exposure stimulus CHIR 99021
relationship: RO:0002309 CHEBI:91091 ! has exposure stimulus CHIR 99021

[Term]
id: ECTO:9002677
name: exposure to chitooligosaccharide
def: "An exposure to chitooligosaccharide." []
synonym: "chitooligosaccharide exposure" EXACT []
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23104 ! has exposure stimulus chitooligosaccharide
relationship: RO:0002309 CHEBI:23104 ! has exposure stimulus chitooligosaccharide

[Term]
id: ECTO:9002678
name: exposure to Chlorin E6
def: "An exposure to Chlorin E6." []
synonym: "Chlorin E6 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:168630 ! has exposure stimulus Chlorin E6
relationship: RO:0002309 CHEBI:168630 ! has exposure stimulus Chlorin E6

[Term]
id: ECTO:9002679
name: exposure to chlorpromazine hydrochloride
def: "An exposure to chlorpromazine hydrochloride." []
synonym: "chlorpromazine hydrochloride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3649 ! has exposure stimulus chlorpromazine hydrochloride
relationship: RO:0002309 CHEBI:3649 ! has exposure stimulus chlorpromazine hydrochloride

[Term]
id: ECTO:9002680
name: exposure to cyclodextrin
def: "An exposure to cyclodextrin." []
synonym: "cyclodextrin exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:23456 ! has exposure stimulus cyclodextrin
relationship: RO:0002309 CHEBI:23456 ! has exposure stimulus cyclodextrin

[Term]
id: ECTO:9002681
name: exposure to dasatinib(1+)
def: "An exposure to dasatinib(1+)." []
synonym: "dasatinib(1+) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:190514 ! has exposure stimulus dasatinib(1+)
relationship: RO:0002309 CHEBI:190514 ! has exposure stimulus dasatinib(1+)

[Term]
id: ECTO:9002682
name: exposure to diallyl trisulfide
def: "An exposure to diallyl trisulfide." []
synonym: "diallyl trisulfide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78492 ! has exposure stimulus diallyl trisulfide
relationship: RO:0002309 CHEBI:78492 ! has exposure stimulus diallyl trisulfide

[Term]
id: ECTO:9002683
name: exposure to didanosine
def: "An exposure to didanosine." []
synonym: "didanosine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:490877 ! has exposure stimulus didanosine
relationship: RO:0002309 CHEBI:490877 ! has exposure stimulus didanosine

[Term]
id: ECTO:9002684
name: exposure to dinitrogen
def: "An exposure to dinitrogen." []
synonym: "dinitrogen exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17997 ! has exposure stimulus dinitrogen
relationship: RO:0002309 CHEBI:17997 ! has exposure stimulus dinitrogen

[Term]
id: ECTO:9002685
name: exposure to efavirenz
def: "An exposure to efavirenz." []
synonym: "efavirenz exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:119486 ! has exposure stimulus efavirenz
relationship: RO:0002309 CHEBI:119486 ! has exposure stimulus efavirenz

[Term]
id: ECTO:9002686
name: exposure to fludarabine phosphate
def: "An exposure to fludarabine phosphate." []
synonym: "fludarabine phosphate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63599 ! has exposure stimulus fludarabine phosphate
relationship: RO:0002309 CHEBI:63599 ! has exposure stimulus fludarabine phosphate

[Term]
id: ECTO:9002687
name: exposure to iridium(3+)
def: "An exposure to iridium(3+)." []
synonym: "iridium(3+) exposure" EXACT []
is_a: ECTO:0000481 ! exposure to transition element
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49704 ! has exposure stimulus iridium(3+)
relationship: RO:0002309 CHEBI:49704 ! has exposure stimulus iridium(3+)

[Term]
id: ECTO:9002688
name: exposure to L-arginine, methyl ester
def: "An exposure to L-arginine, methyl ester." []
synonym: "L-arginine, methyl ester exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:184062 ! has exposure stimulus L-arginine, methyl ester
relationship: RO:0002309 CHEBI:184062 ! has exposure stimulus L-arginine, methyl ester

[Term]
id: ECTO:9002689
name: exposure to lysophosphatidic acid
def: "An exposure to lysophosphatidic acid." []
synonym: "lysophosphatidic acid exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000284 ! exposure to organophosphorus compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132742 ! has exposure stimulus lysophosphatidic acid
relationship: RO:0002309 CHEBI:132742 ! has exposure stimulus lysophosphatidic acid

[Term]
id: ECTO:9002690
name: exposure to metamizole(1-)
def: "An exposure to metamizole(1-)." []
synonym: "metamizole(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62086 ! has exposure stimulus metamizole(1-)
relationship: RO:0002309 CHEBI:62086 ! has exposure stimulus metamizole(1-)

[Term]
id: ECTO:9002691
name: exposure to phytosphingosine(1+)
def: "An exposure to phytosphingosine(1+)." []
synonym: "phytosphingosine(1+) exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000304 ! exposure to ammonium ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64124 ! has exposure stimulus phytosphingosine(1+)
relationship: RO:0002309 CHEBI:64124 ! has exposure stimulus phytosphingosine(1+)

[Term]
id: ECTO:9002692
name: exposure to rosiglitazone(1-)
def: "An exposure to rosiglitazone(1-)." []
synonym: "rosiglitazone(1-) exposure" EXACT []
is_a: ECTO:9000013 ! exposure to thiazolidinediones
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:188074 ! has exposure stimulus rosiglitazone(1-)
relationship: RO:0002309 CHEBI:188074 ! has exposure stimulus rosiglitazone(1-)

[Term]
id: ECTO:9002693
name: exposure to sodium benzoate
def: "An exposure to sodium benzoate." []
synonym: "sodium benzoate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000021 ! exposure to alkali metal salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:113455 ! has exposure stimulus sodium benzoate
relationship: RO:0002309 CHEBI:113455 ! has exposure stimulus sodium benzoate

[Term]
id: ECTO:9002694
name: exposure to teixobactin
def: "An exposure to teixobactin." []
synonym: "teixobactin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84192 ! has exposure stimulus teixobactin
relationship: RO:0002309 CHEBI:84192 ! has exposure stimulus teixobactin

[Term]
id: ECTO:9002695
name: exposure to Tri-2-ethylhexyl trimellitate
def: "An exposure to Tri-2-ethylhexyl trimellitate." []
synonym: "Tri-2-ethylhexyl trimellitate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:184113 ! has exposure stimulus Tri-2-ethylhexyl trimellitate
relationship: RO:0002309 CHEBI:184113 ! has exposure stimulus Tri-2-ethylhexyl trimellitate

[Term]
id: ECTO:9002696
name: exposure to Fucosyllactose
def: "An exposure to Fucosyllactose." []
synonym: "Fucosyllactose exposure" EXACT []
is_a: ECTO:9002565 ! exposure to oligosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:175787 ! has exposure stimulus Fucosyllactose
relationship: RO:0002309 CHEBI:175787 ! has exposure stimulus Fucosyllactose

[Term]
id: ECTO:9002697
name: exposure to 3-hydroxyphenylacetate
def: "An exposure to 3-hydroxyphenylacetate." []
synonym: "3-hydroxyphenylacetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:58149 ! has exposure stimulus 3-hydroxyphenylacetate
relationship: RO:0002309 CHEBI:58149 ! has exposure stimulus 3-hydroxyphenylacetate

[Term]
id: ECTO:9002698
name: exposure to 4-Bromo-9-(iodomethyl)-1,5,12-trimethyl-8-oxatricyclo dodeca-2,4,6-triene
def: "An exposure to 4-Bromo-9-(iodomethyl)-1,5,12-trimethyl-8-oxatricyclo dodeca-2,4,6-triene." []
synonym: "4-Bromo-9-(iodomethyl)-1,5,12-trimethyl-8-oxatricyclo dodeca-2,4,6-triene exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:203402 ! has exposure stimulus 4-Bromo-9-(iodomethyl)-1,5,12-trimethyl-8-oxatricyclo dodeca-2,4,6-triene
relationship: RO:0002309 CHEBI:203402 ! has exposure stimulus 4-Bromo-9-(iodomethyl)-1,5,12-trimethyl-8-oxatricyclo dodeca-2,4,6-triene

[Term]
id: ECTO:9002699
name: exposure to 4-hydroxyphenylacetate
def: "An exposure to 4-hydroxyphenylacetate." []
synonym: "4-hydroxyphenylacetate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48999 ! has exposure stimulus 4-hydroxyphenylacetate
relationship: RO:0002309 CHEBI:48999 ! has exposure stimulus 4-hydroxyphenylacetate

[Term]
id: ECTO:9002700
name: exposure to serine
def: "An exposure to serine." []
synonym: "serine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17822 ! has exposure stimulus serine
relationship: RO:0002309 CHEBI:17822 ! has exposure stimulus serine

[Term]
id: ECTO:9002701
name: exposure to acetohydroxamic acid
def: "An exposure to acetohydroxamic acid." []
synonym: "acetohydroxamic acid exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27777 ! has exposure stimulus acetohydroxamic acid
relationship: RO:0002309 CHEBI:27777 ! has exposure stimulus acetohydroxamic acid

[Term]
id: ECTO:9002702
name: exposure to 3-methyl-2-oxovaleric acid
def: "An exposure to 3-methyl-2-oxovaleric acid." []
synonym: "3-methyl-2-oxovaleric acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35932 ! has exposure stimulus 3-methyl-2-oxovaleric acid
relationship: RO:0002309 CHEBI:35932 ! has exposure stimulus 3-methyl-2-oxovaleric acid

[Term]
id: ECTO:9002703
name: exposure to 5-oxoproline
def: "An exposure to 5-oxoproline." []
synonym: "5-oxoproline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16010 ! has exposure stimulus 5-oxoproline
relationship: RO:0002309 CHEBI:16010 ! has exposure stimulus 5-oxoproline

[Term]
id: ECTO:9002704
name: exposure to aflatoxin B1
def: "An exposure to aflatoxin B1." []
synonym: "aflatoxin B1 exposure" EXACT []
is_a: ECTO:0001108 ! exposure to aflatoxin
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:2504 ! has exposure stimulus aflatoxin B1
relationship: RO:0002309 CHEBI:2504 ! has exposure stimulus aflatoxin B1

[Term]
id: ECTO:9002705
name: exposure to MK-2206
def: "An exposure to MK-2206." []
synonym: "MK-2206 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:67271 ! has exposure stimulus MK-2206
relationship: RO:0002309 CHEBI:67271 ! has exposure stimulus MK-2206

[Term]
id: ECTO:9002706
name: exposure to alexidine
def: "An exposure to alexidine." []
synonym: "alexidine exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53661 ! has exposure stimulus alexidine
relationship: RO:0002309 CHEBI:53661 ! has exposure stimulus alexidine

[Term]
id: ECTO:9002707
name: exposure to L-alanine
def: "An exposure to L-alanine." []
synonym: "L-alanine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16977 ! has exposure stimulus L-alanine
relationship: RO:0002309 CHEBI:16977 ! has exposure stimulus L-alanine

[Term]
id: ECTO:9002708
name: exposure to threonine
def: "An exposure to threonine." []
synonym: "threonine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26986 ! has exposure stimulus threonine
relationship: RO:0002309 CHEBI:26986 ! has exposure stimulus threonine

[Term]
id: ECTO:9002709
name: exposure to ampicillin(1-)
def: "An exposure to ampicillin(1-)." []
synonym: "ampicillin(1-) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50658 ! has exposure stimulus ampicillin(1-)
relationship: RO:0002309 CHEBI:50658 ! has exposure stimulus ampicillin(1-)

[Term]
id: ECTO:9002710
name: exposure to etanercept
def: "An exposure to etanercept." []
synonym: "etanercept exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4875 ! has exposure stimulus etanercept
relationship: RO:0002309 CHEBI:4875 ! has exposure stimulus etanercept

[Term]
id: ECTO:9002711
name: exposure to minocycline
def: "An exposure to minocycline." []
synonym: "minocycline exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50694 ! has exposure stimulus minocycline
relationship: RO:0002309 CHEBI:50694 ! has exposure stimulus minocycline

[Term]
id: ECTO:9002712
name: exposure to cefoperazone
def: "An exposure to cefoperazone." []
synonym: "cefoperazone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3493 ! has exposure stimulus cefoperazone
relationship: RO:0002309 CHEBI:3493 ! has exposure stimulus cefoperazone

[Term]
id: ECTO:9002713
name: exposure to nortriptyline
def: "An exposure to nortriptyline." []
synonym: "nortriptyline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7640 ! has exposure stimulus nortriptyline
relationship: RO:0002309 CHEBI:7640 ! has exposure stimulus nortriptyline

[Term]
id: ECTO:9002714
name: exposure to atovaquone
def: "An exposure to atovaquone." []
synonym: "atovaquone exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9001246 ! exposure to quinone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:575568 ! has exposure stimulus atovaquone
relationship: RO:0002309 CHEBI:575568 ! has exposure stimulus atovaquone

[Term]
id: ECTO:9002715
name: exposure to apixaban
def: "An exposure to apixaban." []
synonym: "apixaban exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72296 ! has exposure stimulus apixaban
relationship: RO:0002309 CHEBI:72296 ! has exposure stimulus apixaban

[Term]
id: ECTO:9002716
name: exposure to Arctiin
def: "An exposure to Arctiin." []
synonym: "Arctiin exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9000436 ! exposure to glycoside
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80793 ! has exposure stimulus Arctiin
relationship: RO:0002309 CHEBI:80793 ! has exposure stimulus Arctiin

[Term]
id: ECTO:9002717
name: exposure to asparagine
def: "An exposure to asparagine." []
synonym: "asparagine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22653 ! has exposure stimulus asparagine
relationship: RO:0002309 CHEBI:22653 ! has exposure stimulus asparagine

[Term]
id: ECTO:9002718
name: exposure to aspartate
def: "An exposure to aspartate." []
synonym: "aspartate exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132943 ! has exposure stimulus aspartate
relationship: RO:0002309 CHEBI:132943 ! has exposure stimulus aspartate

[Term]
id: ECTO:9002719
name: exposure to astaxanthin
def: "An exposure to astaxanthin." []
synonym: "astaxanthin exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:40968 ! has exposure stimulus astaxanthin
relationship: RO:0002309 CHEBI:40968 ! has exposure stimulus astaxanthin

[Term]
id: ECTO:9002720
name: exposure to atazanavir
def: "An exposure to atazanavir." []
synonym: "atazanavir exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:37924 ! has exposure stimulus atazanavir
relationship: RO:0002309 CHEBI:37924 ! has exposure stimulus atazanavir

[Term]
id: ECTO:9002721
name: exposure to KU-55933
def: "An exposure to KU-55933." []
synonym: "KU-55933 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:228209 ! has exposure stimulus KU-55933
relationship: RO:0002309 CHEBI:228209 ! has exposure stimulus KU-55933

[Term]
id: ECTO:9002722
name: exposure to Atractylodin
def: "An exposure to Atractylodin." []
synonym: "Atractylodin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80795 ! has exposure stimulus Atractylodin
relationship: RO:0002309 CHEBI:80795 ! has exposure stimulus Atractylodin

[Term]
id: ECTO:9002723
name: exposure to Avasimibe
def: "An exposure to Avasimibe." []
synonym: "Avasimibe exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:177719 ! has exposure stimulus Avasimibe
relationship: RO:0002309 CHEBI:177719 ! has exposure stimulus Avasimibe

[Term]
id: ECTO:9002724
name: exposure to baricitinib
def: "An exposure to baricitinib." []
synonym: "baricitinib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9001359 ! exposure to sulfonamide
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:95341 ! has exposure stimulus baricitinib
relationship: RO:0002309 CHEBI:95341 ! has exposure stimulus baricitinib

[Term]
id: ECTO:9002725
name: exposure to bedaquiline
def: "An exposure to bedaquiline." []
synonym: "bedaquiline exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000251 ! exposure to stilbenoid
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72292 ! has exposure stimulus bedaquiline
relationship: RO:0002309 CHEBI:72292 ! has exposure stimulus bedaquiline

[Term]
id: ECTO:9002726
name: exposure to bile acids
def: "An exposure to bile acids." []
synonym: "bile acids exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138366 ! has exposure stimulus bile acids
relationship: RO:0002309 CHEBI:138366 ! has exposure stimulus bile acids

[Term]
id: ECTO:9002727
name: exposure to bismuth atom
def: "An exposure to bismuth atom." []
synonym: "bismuth atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33301 ! has exposure stimulus bismuth atom
relationship: RO:0002309 CHEBI:33301 ! has exposure stimulus bismuth atom

[Term]
id: ECTO:9002728
name: exposure to bisoprolol
def: "An exposure to bisoprolol." []
synonym: "bisoprolol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3127 ! has exposure stimulus bisoprolol
relationship: RO:0002309 CHEBI:3127 ! has exposure stimulus bisoprolol

[Term]
id: ECTO:9002729
name: exposure to bleomycin A2
def: "An exposure to bleomycin A2." []
synonym: "bleomycin A2 exposure" EXACT []
is_a: ECTO:9000510 ! exposure to bleomycin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3139 ! has exposure stimulus bleomycin A2
relationship: RO:0002309 CHEBI:3139 ! has exposure stimulus bleomycin A2

[Term]
id: ECTO:9002730
name: exposure to brequinar
def: "An exposure to brequinar." []
synonym: "brequinar exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000056 ! exposure to biphenyls
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:177387 ! has exposure stimulus brequinar
relationship: RO:0002309 CHEBI:177387 ! has exposure stimulus brequinar

[Term]
id: ECTO:9002731
name: exposure to Brilliant Blue
def: "An exposure to Brilliant Blue." []
synonym: "Brilliant Blue exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82411 ! has exposure stimulus Brilliant Blue
relationship: RO:0002309 CHEBI:82411 ! has exposure stimulus Brilliant Blue

[Term]
id: ECTO:9002732
name: exposure to buprenorphine
def: "An exposure to buprenorphine." []
synonym: "buprenorphine exposure" EXACT []
is_a: ECTO:9000200 ! exposure to isoquinoline alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3216 ! has exposure stimulus buprenorphine
relationship: RO:0002309 CHEBI:3216 ! has exposure stimulus buprenorphine

[Term]
id: ECTO:9002733
name: exposure to Bupropion hydrochloride
def: "An exposure to Bupropion hydrochloride." []
synonym: "Bupropion hydrochloride exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3220 ! has exposure stimulus Bupropion hydrochloride
relationship: RO:0002309 CHEBI:3220 ! has exposure stimulus Bupropion hydrochloride

[Term]
id: ECTO:9002734
name: exposure to busulfan
def: "An exposure to busulfan." []
synonym: "busulfan exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28901 ! has exposure stimulus busulfan
relationship: RO:0002309 CHEBI:28901 ! has exposure stimulus busulfan

[Term]
id: ECTO:9002735
name: exposure to butyric acid
def: "An exposure to butyric acid." []
synonym: "butyric acid exposure" EXACT []
is_a: ECTO:9002880 ! exposure to short-chain fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30772 ! has exposure stimulus butyric acid
relationship: RO:0002309 CHEBI:30772 ! has exposure stimulus butyric acid

[Term]
id: ECTO:9002736
name: exposure to ceruletide
def: "An exposure to ceruletide." []
synonym: "ceruletide exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59219 ! has exposure stimulus ceruletide
relationship: RO:0002309 CHEBI:59219 ! has exposure stimulus ceruletide

[Term]
id: ECTO:9002737
name: exposure to capsaicin
def: "An exposure to capsaicin." []
synonym: "capsaicin exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3374 ! has exposure stimulus capsaicin
relationship: RO:0002309 CHEBI:3374 ! has exposure stimulus capsaicin

[Term]
id: ECTO:9002738
name: exposure to carfilzomib
def: "An exposure to carfilzomib." []
synonym: "carfilzomib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65347 ! has exposure stimulus carfilzomib
relationship: RO:0002309 CHEBI:65347 ! has exposure stimulus carfilzomib

[Term]
id: ECTO:9002739
name: exposure to catalpol
def: "An exposure to catalpol." []
synonym: "catalpol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:69797 ! has exposure stimulus catalpol
relationship: RO:0002309 CHEBI:69797 ! has exposure stimulus catalpol

[Term]
id: ECTO:9002740
name: exposure to CB-5083
def: "An exposure to CB-5083." []
synonym: "CB-5083 exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:232521 ! has exposure stimulus CB-5083
relationship: RO:0002309 CHEBI:232521 ! has exposure stimulus CB-5083

[Term]
id: ECTO:9002741
name: exposure to JWH-133
def: "An exposure to JWH-133." []
synonym: "JWH-133 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:146243 ! has exposure stimulus JWH-133
relationship: RO:0002309 CHEBI:146243 ! has exposure stimulus JWH-133

[Term]
id: ECTO:9002742
name: exposure to cefadroxil
def: "An exposure to cefadroxil." []
synonym: "cefadroxil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3479 ! has exposure stimulus cefadroxil
relationship: RO:0002309 CHEBI:3479 ! has exposure stimulus cefadroxil

[Term]
id: ECTO:9002743
name: exposure to Centrinone
def: "An exposure to Centrinone." []
synonym: "Centrinone exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:747302 ! has exposure stimulus Centrinone
relationship: RO:0002309 CHEBI:747302 ! has exposure stimulus Centrinone

[Term]
id: ECTO:9002744
name: exposure to chaetocin
def: "An exposure to chaetocin." []
synonym: "chaetocin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68747 ! has exposure stimulus chaetocin
relationship: RO:0002309 CHEBI:68747 ! has exposure stimulus chaetocin

[Term]
id: ECTO:9002745
name: exposure to chitosan
def: "An exposure to chitosan." []
synonym: "chitosan exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16261 ! has exposure stimulus chitosan
relationship: RO:0002309 CHEBI:16261 ! has exposure stimulus chitosan

[Term]
id: ECTO:9002746
name: exposure to chlorite
def: "An exposure to chlorite." []
synonym: "chlorite exposure" EXACT []
is_a: ECTO:9002504 ! exposure to chlorine oxoanion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17441 ! has exposure stimulus chlorite
relationship: RO:0002309 CHEBI:17441 ! has exposure stimulus chlorite

[Term]
id: ECTO:9002747
name: exposure to chlorogenic acid
def: "An exposure to chlorogenic acid." []
synonym: "chlorogenic acid exposure" EXACT []
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002562 ! exposure to polyphenol
is_a: ECTO:9002579 ! exposure to quinic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16112 ! has exposure stimulus chlorogenic acid
relationship: RO:0002309 CHEBI:16112 ! has exposure stimulus chlorogenic acid

[Term]
id: ECTO:9002748
name: exposure to cholic acid
def: "An exposure to cholic acid." []
synonym: "cholic acid exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16359 ! has exposure stimulus cholic acid
relationship: RO:0002309 CHEBI:16359 ! has exposure stimulus cholic acid

[Term]
id: ECTO:9002749
name: exposure to choline
def: "An exposure to choline." []
synonym: "choline exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:9000304 ! exposure to ammonium ion
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15354 ! has exposure stimulus choline
relationship: RO:0002309 CHEBI:15354 ! has exposure stimulus choline

[Term]
id: ECTO:9002750
name: exposure to ferric ammonium citrate
def: "An exposure to ferric ammonium citrate." []
synonym: "ferric ammonium citrate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31604 ! has exposure stimulus ferric ammonium citrate
relationship: RO:0002309 CHEBI:31604 ! has exposure stimulus ferric ammonium citrate

[Term]
id: ECTO:9002751
name: exposure to 4,5,6,7-TETRABROMOBENZOTRIAZOLE
def: "An exposure to 4,5,6,7-TETRABROMOBENZOTRIAZOLE." []
synonym: "4,5,6,7-TETRABROMOBENZOTRIAZOLE exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:47697 ! has exposure stimulus 4,5,6,7-TETRABROMOBENZOTRIAZOLE
relationship: RO:0002309 CHEBI:47697 ! has exposure stimulus 4,5,6,7-TETRABROMOBENZOTRIAZOLE

[Term]
id: ECTO:9002752
name: exposure to cobalt chloride hexahydrate
def: "An exposure to cobalt chloride hexahydrate." []
synonym: "cobalt chloride hexahydrate exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:53503 ! has exposure stimulus cobalt chloride hexahydrate
relationship: RO:0002309 CHEBI:53503 ! has exposure stimulus cobalt chloride hexahydrate

[Term]
id: ECTO:9002753
name: exposure to Collagen
def: "An exposure to Collagen." []
synonym: "Collagen exposure" EXACT []
is_a: ECTO:9000106 ! exposure to polymer
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3815 ! has exposure stimulus Collagen
relationship: RO:0002309 CHEBI:3815 ! has exposure stimulus Collagen

[Term]
id: ECTO:9002754
name: exposure to sildenafil
def: "An exposure to sildenafil." []
synonym: "sildenafil exposure" EXACT []
is_a: ECTO:9001359 ! exposure to sulfonamide
is_a: ECTO:9002871 ! exposure to pyrazolopyrimidine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9139 ! has exposure stimulus sildenafil
relationship: RO:0002309 CHEBI:9139 ! has exposure stimulus sildenafil

[Term]
id: ECTO:9002755
name: exposure to Coronatine
def: "An exposure to Coronatine." []
synonym: "Coronatine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80730 ! has exposure stimulus Coronatine
relationship: RO:0002309 CHEBI:80730 ! has exposure stimulus Coronatine

[Term]
id: ECTO:9002756
name: exposure to crystalline cellulose
def: "An exposure to crystalline cellulose." []
synonym: "crystalline cellulose exposure" EXACT []
is_a: ECTO:9001339 ! exposure to polysaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62968 ! has exposure stimulus crystalline cellulose
relationship: RO:0002309 CHEBI:62968 ! has exposure stimulus crystalline cellulose

[Term]
id: ECTO:9002757
name: exposure to trans-zeatin
def: "An exposure to trans-zeatin." []
synonym: "trans-zeatin exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16522 ! has exposure stimulus trans-zeatin
relationship: RO:0002309 CHEBI:16522 ! has exposure stimulus trans-zeatin

[Term]
id: ECTO:9002758
name: exposure to Zeatin-7-N-glucoside
def: "An exposure to Zeatin-7-N-glucoside." []
synonym: "Zeatin-7-N-glucoside exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:183694 ! has exposure stimulus Zeatin-7-N-glucoside
relationship: RO:0002309 CHEBI:183694 ! has exposure stimulus Zeatin-7-N-glucoside

[Term]
id: ECTO:9002759
name: exposure to dabigatran etexilate
def: "An exposure to dabigatran etexilate." []
synonym: "dabigatran etexilate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70746 ! has exposure stimulus dabigatran etexilate
relationship: RO:0002309 CHEBI:70746 ! has exposure stimulus dabigatran etexilate

[Term]
id: ECTO:9002760
name: exposure to gonadotropin releasing hormone agonist
def: "An exposure to gonadotropin releasing hormone agonist." []
synonym: "gonadotropin releasing hormone agonist exposure" EXACT []
is_a: ECTO:0000509 ! exposure to drug
is_a: ECTO:0000672 ! exposure to agonist
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:63533 ! has exposure stimulus gonadotropin releasing hormone agonist
relationship: RO:0002309 CHEBI:63533 ! has exposure stimulus gonadotropin releasing hormone agonist

[Term]
id: ECTO:9002761
name: exposure to hydroxytyrosol
def: "An exposure to hydroxytyrosol." []
synonym: "hydroxytyrosol exposure" EXACT []
is_a: ECTO:9001334 ! exposure to primary alcohol
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68889 ! has exposure stimulus hydroxytyrosol
relationship: RO:0002309 CHEBI:68889 ! has exposure stimulus hydroxytyrosol

[Term]
id: ECTO:9002762
name: exposure to deferasirox
def: "An exposure to deferasirox." []
synonym: "deferasirox exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:49005 ! has exposure stimulus deferasirox
relationship: RO:0002309 CHEBI:49005 ! has exposure stimulus deferasirox

[Term]
id: ECTO:9002763
name: exposure to hispidulin
def: "An exposure to hispidulin." []
synonym: "hispidulin exposure" EXACT []
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75902 ! has exposure stimulus hispidulin
relationship: RO:0002309 CHEBI:75902 ! has exposure stimulus hispidulin

[Term]
id: ECTO:9002764
name: exposure to L-asparagine
def: "An exposure to L-asparagine." []
synonym: "L-asparagine exposure" EXACT []
is_a: ECTO:9002717 ! exposure to asparagine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17196 ! has exposure stimulus L-asparagine
relationship: RO:0002309 CHEBI:17196 ! has exposure stimulus L-asparagine

[Term]
id: ECTO:9002765
name: exposure to L-leucine
def: "An exposure to L-leucine." []
synonym: "L-leucine exposure" EXACT []
is_a: ECTO:9000269 ! exposure to leucine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15603 ! has exposure stimulus L-leucine
relationship: RO:0002309 CHEBI:15603 ! has exposure stimulus L-leucine

[Term]
id: ECTO:9002766
name: exposure to omega-3 fatty acid
def: "An exposure to omega-3 fatty acid." []
synonym: "omega-3 fatty acid exposure" EXACT []
is_a: ECTO:9002507 ! exposure to polyunsaturated fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25681 ! has exposure stimulus omega-3 fatty acid
relationship: RO:0002309 CHEBI:25681 ! has exposure stimulus omega-3 fatty acid

[Term]
id: ECTO:9002767
name: exposure to lysine
def: "An exposure to lysine." []
synonym: "lysine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25094 ! has exposure stimulus lysine
relationship: RO:0002309 CHEBI:25094 ! has exposure stimulus lysine

[Term]
id: ECTO:9002768
name: exposure to arabinose
def: "An exposure to arabinose." []
synonym: "arabinose exposure" EXACT []
is_a: ECTO:9000239 ! exposure to monosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:22599 ! has exposure stimulus arabinose
relationship: RO:0002309 CHEBI:22599 ! has exposure stimulus arabinose

[Term]
id: ECTO:9002769
name: exposure to malate
def: "An exposure to malate." []
synonym: "malate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25115 ! has exposure stimulus malate
relationship: RO:0002309 CHEBI:25115 ! has exposure stimulus malate

[Term]
id: ECTO:9002770
name: exposure to dimethyl fumarate
def: "An exposure to dimethyl fumarate." []
synonym: "dimethyl fumarate exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76004 ! has exposure stimulus dimethyl fumarate
relationship: RO:0002309 CHEBI:76004 ! has exposure stimulus dimethyl fumarate

[Term]
id: ECTO:9002771
name: exposure to dolutegravir
def: "An exposure to dolutegravir." []
synonym: "dolutegravir exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:76010 ! has exposure stimulus dolutegravir
relationship: RO:0002309 CHEBI:76010 ! has exposure stimulus dolutegravir

[Term]
id: ECTO:9002772
name: exposure to domoic acid
def: "An exposure to domoic acid." []
synonym: "domoic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:34727 ! has exposure stimulus domoic acid
relationship: RO:0002309 CHEBI:34727 ! has exposure stimulus domoic acid

[Term]
id: ECTO:9002773
name: exposure to Gly-Gly-Leu
def: "An exposure to Gly-Gly-Leu." []
synonym: "Gly-Gly-Leu exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:73904 ! has exposure stimulus Gly-Gly-Leu
relationship: RO:0002309 CHEBI:73904 ! has exposure stimulus Gly-Gly-Leu

[Term]
id: ECTO:9002774
name: exposure to eliglustat
def: "An exposure to eliglustat." []
synonym: "eliglustat exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:82752 ! has exposure stimulus eliglustat
relationship: RO:0002309 CHEBI:82752 ! has exposure stimulus eliglustat

[Term]
id: ECTO:9002775
name: exposure to ellagic acid
def: "An exposure to ellagic acid." []
synonym: "ellagic acid exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4775 ! has exposure stimulus ellagic acid
relationship: RO:0002309 CHEBI:4775 ! has exposure stimulus ellagic acid

[Term]
id: ECTO:9002776
name: exposure to emodin
def: "An exposure to emodin." []
synonym: "emodin exposure" EXACT []
is_a: ECTO:9001246 ! exposure to quinone
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:42223 ! has exposure stimulus emodin
relationship: RO:0002309 CHEBI:42223 ! has exposure stimulus emodin

[Term]
id: ECTO:9002777
name: exposure to enrofloxacin
def: "An exposure to enrofloxacin." []
synonym: "enrofloxacin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:35720 ! has exposure stimulus enrofloxacin
relationship: RO:0002309 CHEBI:35720 ! has exposure stimulus enrofloxacin

[Term]
id: ECTO:9002778
name: exposure to ergosterol
def: "An exposure to ergosterol." []
synonym: "ergosterol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000264 ! exposure to sterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16933 ! has exposure stimulus ergosterol
relationship: RO:0002309 CHEBI:16933 ! has exposure stimulus ergosterol

[Term]
id: ECTO:9002779
name: exposure to ertapenem
def: "An exposure to ertapenem." []
synonym: "ertapenem exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:404903 ! has exposure stimulus ertapenem
relationship: RO:0002309 CHEBI:404903 ! has exposure stimulus ertapenem

[Term]
id: ECTO:9002780
name: exposure to escitalopram
def: "An exposure to escitalopram." []
synonym: "escitalopram exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9002139 ! exposure to nitrile
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36791 ! has exposure stimulus escitalopram
relationship: RO:0002309 CHEBI:36791 ! has exposure stimulus escitalopram

[Term]
id: ECTO:9002781
name: exposure to esculetin
def: "An exposure to esculetin." []
synonym: "esculetin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000345 ! exposure to phenylpropanoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:490095 ! has exposure stimulus esculetin
relationship: RO:0002309 CHEBI:490095 ! has exposure stimulus esculetin

[Term]
id: ECTO:9002782
name: exposure to Flurogestone acetate
def: "An exposure to Flurogestone acetate." []
synonym: "Flurogestone acetate exposure" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
is_a: ECTO:0000258 ! exposure to steroid hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:79932 ! has exposure stimulus Flurogestone acetate
relationship: RO:0002309 CHEBI:79932 ! has exposure stimulus Flurogestone acetate

[Term]
id: ECTO:9002783
name: exposure to Euphol
def: "An exposure to Euphol." []
synonym: "Euphol exposure" EXACT []
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:4940 ! has exposure stimulus Euphol
relationship: RO:0002309 CHEBI:4940 ! has exposure stimulus Euphol

[Term]
id: ECTO:9002784
name: exposure to everolimus
def: "An exposure to everolimus." []
synonym: "everolimus exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68478 ! has exposure stimulus everolimus
relationship: RO:0002309 CHEBI:68478 ! has exposure stimulus everolimus

[Term]
id: ECTO:9002785
name: exposure to silibinin
def: "An exposure to silibinin." []
synonym: "silibinin exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9002562 ! exposure to polyphenol
is_a: ECTO:9002813 ! exposure to flavonoids
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9144 ! has exposure stimulus silibinin
relationship: RO:0002309 CHEBI:9144 ! has exposure stimulus silibinin

[Term]
id: ECTO:9002786
name: exposure to 24-hydroxycholesterol
def: "An exposure to 24-hydroxycholesterol." []
synonym: "24-hydroxycholesterol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000264 ! exposure to sterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50515 ! has exposure stimulus 24-hydroxycholesterol
relationship: RO:0002309 CHEBI:50515 ! has exposure stimulus 24-hydroxycholesterol

[Term]
id: ECTO:9002787
name: exposure to sulfite
def: "An exposure to sulfite." []
synonym: "sulfite exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17359 ! has exposure stimulus sulfite
relationship: RO:0002309 CHEBI:17359 ! has exposure stimulus sulfite

[Term]
id: ECTO:9002788
name: exposure to N-acetylglucosamine
def: "An exposure to N-acetylglucosamine." []
synonym: "N-acetylglucosamine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:59640 ! has exposure stimulus N-acetylglucosamine
relationship: RO:0002309 CHEBI:59640 ! has exposure stimulus N-acetylglucosamine

[Term]
id: ECTO:9002789
name: exposure to oleamide
def: "An exposure to oleamide." []
synonym: "oleamide exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:116314 ! has exposure stimulus oleamide
relationship: RO:0002309 CHEBI:116314 ! has exposure stimulus oleamide

[Term]
id: ECTO:9002790
name: exposure to phytosphingosine
def: "An exposure to phytosphingosine." []
synonym: "phytosphingosine exposure" EXACT []
is_a: ECTO:0000200 ! exposure to lipid
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46961 ! has exposure stimulus phytosphingosine
relationship: RO:0002309 CHEBI:46961 ! has exposure stimulus phytosphingosine

[Term]
id: ECTO:9002791
name: exposure to protectin D1
def: "An exposure to protectin D1." []
synonym: "protectin D1 exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9002507 ! exposure to polyunsaturated fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:138655 ! has exposure stimulus protectin D1
relationship: RO:0002309 CHEBI:138655 ! has exposure stimulus protectin D1

[Term]
id: ECTO:9002792
name: exposure to zymosterol
def: "An exposure to zymosterol." []
synonym: "zymosterol exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000264 ! exposure to sterol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18252 ! has exposure stimulus zymosterol
relationship: RO:0002309 CHEBI:18252 ! has exposure stimulus zymosterol

[Term]
id: ECTO:9002793
name: exposure to tazemetostat
def: "An exposure to tazemetostat." []
synonym: "tazemetostat exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:231598 ! has exposure stimulus tazemetostat
relationship: RO:0002309 CHEBI:231598 ! has exposure stimulus tazemetostat

[Term]
id: ECTO:9002794
name: exposure to fasudil
def: "An exposure to fasudil." []
synonym: "fasudil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:43871 ! has exposure stimulus fasudil
relationship: RO:0002309 CHEBI:43871 ! has exposure stimulus fasudil

[Term]
id: ECTO:9002795
name: exposure to fleroxacin
def: "An exposure to fleroxacin." []
synonym: "fleroxacin exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9002374 ! exposure to fluoroquinolone antibiotic
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:31810 ! has exposure stimulus fleroxacin
relationship: RO:0002309 CHEBI:31810 ! has exposure stimulus fleroxacin

[Term]
id: ECTO:9002796
name: exposure to fullerene
def: "An exposure to fullerene." []
synonym: "fullerene exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:33416 ! has exposure stimulus fullerene
relationship: RO:0002309 CHEBI:33416 ! has exposure stimulus fullerene

[Term]
id: ECTO:9002797
name: exposure to glutamine
def: "An exposure to glutamine." []
synonym: "glutamine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28300 ! has exposure stimulus glutamine
relationship: RO:0002309 CHEBI:28300 ! has exposure stimulus glutamine

[Term]
id: ECTO:9002798
name: exposure to graphene oxide
def: "An exposure to graphene oxide." []
synonym: "graphene oxide exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132889 ! has exposure stimulus graphene oxide
relationship: RO:0002309 CHEBI:132889 ! has exposure stimulus graphene oxide

[Term]
id: ECTO:9002799
name: exposure to harmol
def: "An exposure to harmol." []
synonym: "harmol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:192558 ! has exposure stimulus harmol
relationship: RO:0002309 CHEBI:192558 ! has exposure stimulus harmol

[Term]
id: ECTO:9002800
name: exposure to hesperidin
def: "An exposure to hesperidin." []
synonym: "hesperidin exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000345 ! exposure to phenylpropanoid
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28775 ! has exposure stimulus hesperidin
relationship: RO:0002309 CHEBI:28775 ! has exposure stimulus hesperidin

[Term]
id: ECTO:9002801
name: exposure to hexanoic acid
def: "An exposure to hexanoic acid." []
synonym: "hexanoic acid exposure" EXACT []
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:30776 ! has exposure stimulus hexanoic acid
relationship: RO:0002309 CHEBI:30776 ! has exposure stimulus hexanoic acid

[Term]
id: ECTO:9002802
name: exposure to inorganic phosphate
def: "An exposure to inorganic phosphate." []
synonym: "inorganic phosphate exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001345 ! exposure to phosphate
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24838 ! has exposure stimulus inorganic phosphate
relationship: RO:0002309 CHEBI:24838 ! has exposure stimulus inorganic phosphate

[Term]
id: ECTO:9002803
name: exposure to uric acid
def: "An exposure to uric acid." []
synonym: "uric acid exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27226 ! has exposure stimulus uric acid
relationship: RO:0002309 CHEBI:27226 ! has exposure stimulus uric acid

[Term]
id: ECTO:9002804
name: exposure to vorinostat
def: "An exposure to vorinostat." []
synonym: "vorinostat exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:45716 ! has exposure stimulus vorinostat
relationship: RO:0002309 CHEBI:45716 ! has exposure stimulus vorinostat

[Term]
id: ECTO:9002805
name: exposure to omacetaxine mepesuccinate
def: "An exposure to omacetaxine mepesuccinate." []
synonym: "omacetaxine mepesuccinate exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000271 ! exposure to alkaloid
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71019 ! has exposure stimulus omacetaxine mepesuccinate
relationship: RO:0002309 CHEBI:71019 ! has exposure stimulus omacetaxine mepesuccinate

[Term]
id: ECTO:9002806
name: exposure to dihydrogen
def: "An exposure to dihydrogen." []
synonym: "dihydrogen exposure" EXACT []
is_a: ECTO:9000172 ! exposure to inorganic compound
is_a: ECTO:9001628 ! exposure to gas molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18276 ! has exposure stimulus dihydrogen
relationship: RO:0002309 CHEBI:18276 ! has exposure stimulus dihydrogen

[Term]
id: ECTO:9002807
name: exposure to hydroxychloroquine(2+)
def: "An exposure to hydroxychloroquine(2+)." []
synonym: "hydroxychloroquine(2+) exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:149564 ! has exposure stimulus hydroxychloroquine(2+)
relationship: RO:0002309 CHEBI:149564 ! has exposure stimulus hydroxychloroquine(2+)

[Term]
id: ECTO:9002808
name: exposure to hyocholic acid
def: "An exposure to hyocholic acid." []
synonym: "hyocholic acid exposure" EXACT []
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000435 ! exposure to bile acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81244 ! has exposure stimulus hyocholic acid
relationship: RO:0002309 CHEBI:81244 ! has exposure stimulus hyocholic acid

[Term]
id: ECTO:9002809
name: exposure to hypericin
def: "An exposure to hypericin." []
synonym: "hypericin exposure" EXACT []
is_a: ECTO:9000433 ! exposure to polycyclic arene
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5835 ! has exposure stimulus hypericin
relationship: RO:0002309 CHEBI:5835 ! has exposure stimulus hypericin

[Term]
id: ECTO:9002810
name: exposure to hypoxanthine
def: "An exposure to hypoxanthine." []
synonym: "hypoxanthine exposure" EXACT []
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17368 ! has exposure stimulus hypoxanthine
relationship: RO:0002309 CHEBI:17368 ! has exposure stimulus hypoxanthine

[Term]
id: ECTO:9002811
name: exposure to icariin
def: "An exposure to icariin." []
synonym: "icariin exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:78420 ! has exposure stimulus icariin
relationship: RO:0002309 CHEBI:78420 ! has exposure stimulus icariin

[Term]
id: ECTO:9002812
name: exposure to imiquimod
def: "An exposure to imiquimod." []
synonym: "imiquimod exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:36704 ! has exposure stimulus imiquimod
relationship: RO:0002309 CHEBI:36704 ! has exposure stimulus imiquimod

[Term]
id: ECTO:9002813
name: exposure to flavonoids
def: "An exposure to flavonoids." []
synonym: "flavonoids exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:72544 ! has exposure stimulus flavonoids
relationship: RO:0002309 CHEBI:72544 ! has exposure stimulus flavonoids

[Term]
id: ECTO:9002814
name: exposure to fluticasone furoate
def: "An exposure to fluticasone furoate." []
synonym: "fluticasone furoate exposure" EXACT []
is_a: ECTO:0000173 ! exposure to corticosteroid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74899 ! has exposure stimulus fluticasone furoate
relationship: RO:0002309 CHEBI:74899 ! has exposure stimulus fluticasone furoate

[Term]
id: ECTO:9002815
name: exposure to sulfide
def: "An exposure to sulfide." []
synonym: "sulfide exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26822 ! has exposure stimulus sulfide
relationship: RO:0002309 CHEBI:26822 ! has exposure stimulus sulfide

[Term]
id: ECTO:9002816
name: exposure to inosine
def: "An exposure to inosine." []
synonym: "inosine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000202 ! exposure to purines
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17596 ! has exposure stimulus inosine
relationship: RO:0002309 CHEBI:17596 ! has exposure stimulus inosine

[Term]
id: ECTO:9002817
name: exposure to iodoacetic acid
def: "An exposure to iodoacetic acid." []
synonym: "iodoacetic acid exposure" EXACT []
is_a: ECTO:9000084 ! exposure to iodine
is_a: ECTO:9002412 ! exposure to haloacetic acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:74571 ! has exposure stimulus iodoacetic acid
relationship: RO:0002309 CHEBI:74571 ! has exposure stimulus iodoacetic acid

[Term]
id: ECTO:9002818
name: exposure to irinotecan
def: "An exposure to irinotecan." []
synonym: "irinotecan exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80630 ! has exposure stimulus irinotecan
relationship: RO:0002309 CHEBI:80630 ! has exposure stimulus irinotecan

[Term]
id: ECTO:9002819
name: exposure to iron(2+) chelator
def: "An exposure to iron(2+) chelator." []
synonym: "iron(2+) chelator exposure" EXACT []
is_a: ECTO:9001779 ! exposure to iron chelator
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38162 ! has exposure stimulus iron(2+) chelator
relationship: RO:0002309 CHEBI:38162 ! has exposure stimulus iron(2+) chelator

[Term]
id: ECTO:9002820
name: exposure to Isocorydine
def: "An exposure to Isocorydine." []
synonym: "Isocorydine exposure" EXACT []
is_a: ECTO:9000200 ! exposure to isoquinoline alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6000 ! has exposure stimulus Isocorydine
relationship: RO:0002309 CHEBI:6000 ! has exposure stimulus Isocorydine

[Term]
id: ECTO:9002821
name: exposure to isoleucine
def: "An exposure to isoleucine." []
synonym: "isoleucine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:24898 ! has exposure stimulus isoleucine
relationship: RO:0002309 CHEBI:24898 ! has exposure stimulus isoleucine

[Term]
id: ECTO:9002822
name: exposure to isoniazide
def: "An exposure to isoniazide." []
synonym: "isoniazide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6030 ! has exposure stimulus isoniazide
relationship: RO:0002309 CHEBI:6030 ! has exposure stimulus isoniazide

[Term]
id: ECTO:9002823
name: exposure to L-citrulline zwitterion
def: "An exposure to L-citrulline zwitterion." []
synonym: "L-citrulline zwitterion exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:57743 ! has exposure stimulus L-citrulline zwitterion
relationship: RO:0002309 CHEBI:57743 ! has exposure stimulus L-citrulline zwitterion

[Term]
id: ECTO:9002824
name: exposure to lumichrome
def: "An exposure to lumichrome." []
synonym: "lumichrome exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17781 ! has exposure stimulus lumichrome
relationship: RO:0002309 CHEBI:17781 ! has exposure stimulus lumichrome

[Term]
id: ECTO:9002825
name: exposure to Luteinizing hormone
def: "An exposure to Luteinizing hormone." []
synonym: "Luteinizing hormone exposure" EXACT []
is_a: ECTO:9000487 ! exposure to glycoprotein
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81568 ! has exposure stimulus Luteinizing hormone
relationship: RO:0002309 CHEBI:81568 ! has exposure stimulus Luteinizing hormone

[Term]
id: ECTO:9002826
name: exposure to maleic acid
def: "An exposure to maleic acid." []
synonym: "maleic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18300 ! has exposure stimulus maleic acid
relationship: RO:0002309 CHEBI:18300 ! has exposure stimulus maleic acid

[Term]
id: ECTO:9002827
name: exposure to malic acid
def: "An exposure to malic acid." []
synonym: "malic acid exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6650 ! has exposure stimulus malic acid
relationship: RO:0002309 CHEBI:6650 ! has exposure stimulus malic acid

[Term]
id: ECTO:9002828
name: exposure to Mdivi-1
def: "An exposure to Mdivi-1." []
synonym: "Mdivi-1 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:232380 ! has exposure stimulus Mdivi-1
relationship: RO:0002309 CHEBI:232380 ! has exposure stimulus Mdivi-1

[Term]
id: ECTO:9002829
name: exposure to melittin
def: "An exposure to melittin." []
synonym: "melittin exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:6736 ! has exposure stimulus melittin
relationship: RO:0002309 CHEBI:6736 ! has exposure stimulus melittin

[Term]
id: ECTO:9002830
name: exposure to mercury(0)
def: "An exposure to mercury(0)." []
synonym: "mercury(0) exposure" EXACT []
is_a: ECTO:0001571 ! exposure to mercury
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16170 ! has exposure stimulus mercury(0)
relationship: RO:0002309 CHEBI:16170 ! has exposure stimulus mercury(0)

[Term]
id: ECTO:9002831
name: exposure to metconazole
def: "An exposure to metconazole." []
synonym: "metconazole exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:81773 ! has exposure stimulus metconazole
relationship: RO:0002309 CHEBI:81773 ! has exposure stimulus metconazole

[Term]
id: ECTO:9002832
name: exposure to sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7-pyrrolo[2,3-d]pyrimidinyl]-2-hydroxycyclopentyl]methyl ester
def: "An exposure to sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7-pyrrolo[2,3-d]pyrimidinyl]-2-hydroxycyclopentyl]methyl ester." []
synonym: "sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7-pyrrolo[2,3-d]pyrimidinyl]-2-hydroxycyclopentyl]methyl ester exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:95028 ! has exposure stimulus sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7-pyrrolo[2,3-d]pyrimidinyl]-2-hydroxycyclopentyl]methyl ester
relationship: RO:0002309 CHEBI:95028 ! has exposure stimulus sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7-pyrrolo[2,3-d]pyrimidinyl]-2-hydroxycyclopentyl]methyl ester

[Term]
id: ECTO:9002833
name: exposure to MnTBAP
def: "An exposure to MnTBAP." []
synonym: "MnTBAP exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233143 ! has exposure stimulus MnTBAP
relationship: RO:0002309 CHEBI:233143 ! has exposure stimulus MnTBAP

[Term]
id: ECTO:9002834
name: exposure to Monensin sodium salt
def: "An exposure to Monensin sodium salt." []
synonym: "Monensin sodium salt exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:201815 ! has exposure stimulus Monensin sodium salt
relationship: RO:0002309 CHEBI:201815 ! has exposure stimulus Monensin sodium salt

[Term]
id: ECTO:9002835
name: exposure to mosapride
def: "An exposure to mosapride." []
synonym: "mosapride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:94373 ! has exposure stimulus mosapride
relationship: RO:0002309 CHEBI:94373 ! has exposure stimulus mosapride

[Term]
id: ECTO:9002836
name: exposure to entinostat
def: "An exposure to entinostat." []
synonym: "entinostat exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:132082 ! has exposure stimulus entinostat
relationship: RO:0002309 CHEBI:132082 ! has exposure stimulus entinostat

[Term]
id: ECTO:9002837
name: exposure to linoleic acid
def: "An exposure to linoleic acid." []
synonym: "linoleic acid exposure" EXACT []
is_a: ECTO:9002507 ! exposure to polyunsaturated fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17351 ! has exposure stimulus linoleic acid
relationship: RO:0002309 CHEBI:17351 ! has exposure stimulus linoleic acid

[Term]
id: ECTO:9002838
name: exposure to mycophenolate mofetil
def: "An exposure to mycophenolate mofetil." []
synonym: "mycophenolate mofetil exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8764 ! has exposure stimulus mycophenolate mofetil
relationship: RO:0002309 CHEBI:8764 ! has exposure stimulus mycophenolate mofetil

[Term]
id: ECTO:9002839
name: exposure to acetyltaurine
def: "An exposure to acetyltaurine." []
synonym: "acetyltaurine exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84415 ! has exposure stimulus acetyltaurine
relationship: RO:0002309 CHEBI:84415 ! has exposure stimulus acetyltaurine

[Term]
id: ECTO:9002840
name: exposure to nandrolone
def: "An exposure to nandrolone." []
synonym: "nandrolone exposure" EXACT []
is_a: ECTO:0000258 ! exposure to steroid hormone
is_a: ECTO:9000044 ! exposure to ketone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7466 ! has exposure stimulus nandrolone
relationship: RO:0002309 CHEBI:7466 ! has exposure stimulus nandrolone

[Term]
id: ECTO:9002841
name: exposure to Remodelin
def: "An exposure to Remodelin." []
synonym: "Remodelin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:747163 ! has exposure stimulus Remodelin
relationship: RO:0002309 CHEBI:747163 ! has exposure stimulus Remodelin

[Term]
id: ECTO:9002842
name: exposure to navitoclax
def: "An exposure to navitoclax." []
synonym: "navitoclax exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:131174 ! has exposure stimulus navitoclax
relationship: RO:0002309 CHEBI:131174 ! has exposure stimulus navitoclax

[Term]
id: ECTO:9002843
name: exposure to nebivolol
def: "An exposure to nebivolol." []
synonym: "nebivolol exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:64022 ! has exposure stimulus nebivolol
relationship: RO:0002309 CHEBI:64022 ! has exposure stimulus nebivolol

[Term]
id: ECTO:9002844
name: exposure to nedocromil
def: "An exposure to nedocromil." []
synonym: "nedocromil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7492 ! has exposure stimulus nedocromil
relationship: RO:0002309 CHEBI:7492 ! has exposure stimulus nedocromil

[Term]
id: ECTO:9002845
name: exposure to vitamin B3
def: "An exposure to vitamin B3." []
synonym: "vitamin B3 exposure" EXACT []
is_a: ECTO:9002026 ! exposure to B vitamin
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:176839 ! has exposure stimulus vitamin B3
relationship: RO:0002309 CHEBI:176839 ! has exposure stimulus vitamin B3

[Term]
id: ECTO:9002846
name: exposure to nicardipine
def: "An exposure to nicardipine." []
synonym: "nicardipine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7550 ! has exposure stimulus nicardipine
relationship: RO:0002309 CHEBI:7550 ! has exposure stimulus nicardipine

[Term]
id: ECTO:9002847
name: exposure to nickel atom
def: "An exposure to nickel atom." []
synonym: "nickel atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28112 ! has exposure stimulus nickel atom
relationship: RO:0002309 CHEBI:28112 ! has exposure stimulus nickel atom

[Term]
id: ECTO:9002848
name: exposure to niclosamide
def: "An exposure to niclosamide." []
synonym: "niclosamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7553 ! has exposure stimulus niclosamide
relationship: RO:0002309 CHEBI:7553 ! has exposure stimulus niclosamide

[Term]
id: ECTO:9002849
name: exposure to Nifurtimox
def: "An exposure to Nifurtimox." []
synonym: "Nifurtimox exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7566 ! has exposure stimulus Nifurtimox
relationship: RO:0002309 CHEBI:7566 ! has exposure stimulus Nifurtimox

[Term]
id: ECTO:9002850
name: exposure to ochratoxin A
def: "An exposure to ochratoxin A." []
synonym: "ochratoxin A exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000470 ! exposure to L-phenylalanine derivative
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7719 ! has exposure stimulus ochratoxin A
relationship: RO:0002309 CHEBI:7719 ! has exposure stimulus ochratoxin A

[Term]
id: ECTO:9002851
name: exposure to okadaic acid
def: "An exposure to okadaic acid." []
synonym: "okadaic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44658 ! has exposure stimulus okadaic acid
relationship: RO:0002309 CHEBI:44658 ! has exposure stimulus okadaic acid

[Term]
id: ECTO:9002852
name: exposure to olaparib
def: "An exposure to olaparib." []
synonym: "olaparib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:83766 ! has exposure stimulus olaparib
relationship: RO:0002309 CHEBI:83766 ! has exposure stimulus olaparib

[Term]
id: ECTO:9002853
name: exposure to oligomycin
def: "An exposure to oligomycin." []
synonym: "oligomycin exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:25675 ! has exposure stimulus oligomycin
relationship: RO:0002309 CHEBI:25675 ! has exposure stimulus oligomycin

[Term]
id: ECTO:9002854
name: exposure to Ondansetron
def: "An exposure to Ondansetron." []
synonym: "Ondansetron exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:7773 ! has exposure stimulus Ondansetron
relationship: RO:0002309 CHEBI:7773 ! has exposure stimulus Ondansetron

[Term]
id: ECTO:9002855
name: exposure to indole-3-carboxylate
def: "An exposure to indole-3-carboxylate." []
synonym: "indole-3-carboxylate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:62448 ! has exposure stimulus indole-3-carboxylate
relationship: RO:0002309 CHEBI:62448 ! has exposure stimulus indole-3-carboxylate

[Term]
id: ECTO:9002856
name: exposure to N-methylserotonin
def: "An exposure to N-methylserotonin." []
synonym: "N-methylserotonin exposure" EXACT []
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:48294 ! has exposure stimulus N-methylserotonin
relationship: RO:0002309 CHEBI:48294 ! has exposure stimulus N-methylserotonin

[Term]
id: ECTO:9002857
name: exposure to anthocyanin
def: "An exposure to anthocyanin." []
synonym: "anthocyanin exposure" EXACT []
is_a: ECTO:9002371 ! exposure to flavonoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38697 ! has exposure stimulus anthocyanin
relationship: RO:0002309 CHEBI:38697 ! has exposure stimulus anthocyanin

[Term]
id: ECTO:9002858
name: exposure to ornithine
def: "An exposure to ornithine." []
synonym: "ornithine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18257 ! has exposure stimulus ornithine
relationship: RO:0002309 CHEBI:18257 ! has exposure stimulus ornithine

[Term]
id: ECTO:9002859
name: exposure to peroxide
def: "An exposure to peroxide." []
synonym: "peroxide exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000172 ! exposure to inorganic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:44785 ! has exposure stimulus peroxide
relationship: RO:0002309 CHEBI:44785 ! has exposure stimulus peroxide

[Term]
id: ECTO:9002860
name: exposure to pazopanib hydrochloride
def: "An exposure to pazopanib hydrochloride." []
synonym: "pazopanib hydrochloride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000077 ! exposure to chlorine
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000409 ! exposure to salt
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:71217 ! has exposure stimulus pazopanib hydrochloride
relationship: RO:0002309 CHEBI:71217 ! has exposure stimulus pazopanib hydrochloride

[Term]
id: ECTO:9002861
name: exposure to arterolane
def: "An exposure to arterolane." []
synonym: "arterolane exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:136054 ! has exposure stimulus arterolane
relationship: RO:0002309 CHEBI:136054 ! has exposure stimulus arterolane

[Term]
id: ECTO:9002862
name: exposure to phencyclidine
def: "An exposure to phencyclidine." []
synonym: "phencyclidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000203 ! exposure to amine
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8058 ! has exposure stimulus phencyclidine
relationship: RO:0002309 CHEBI:8058 ! has exposure stimulus phencyclidine

[Term]
id: ECTO:9002863
name: exposure to phenobarbital
def: "An exposure to phenobarbital." []
synonym: "phenobarbital exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8069 ! has exposure stimulus phenobarbital
relationship: RO:0002309 CHEBI:8069 ! has exposure stimulus phenobarbital

[Term]
id: ECTO:9002864
name: exposure to xylose
def: "An exposure to xylose." []
synonym: "xylose exposure" EXACT []
is_a: ECTO:9000239 ! exposure to monosaccharide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:18222 ! has exposure stimulus xylose
relationship: RO:0002309 CHEBI:18222 ! has exposure stimulus xylose

[Term]
id: ECTO:9002865
name: exposure to pictrelisib
def: "An exposure to pictrelisib." []
synonym: "pictrelisib exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:65326 ! has exposure stimulus pictrelisib
relationship: RO:0002309 CHEBI:65326 ! has exposure stimulus pictrelisib

[Term]
id: ECTO:9002866
name: exposure to Pioglitazone hydrochloride
def: "An exposure to Pioglitazone hydrochloride." []
synonym: "Pioglitazone hydrochloride exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8229 ! has exposure stimulus Pioglitazone hydrochloride
relationship: RO:0002309 CHEBI:8229 ! has exposure stimulus Pioglitazone hydrochloride

[Term]
id: ECTO:9002867
name: exposure to platycodin D
def: "An exposure to platycodin D." []
synonym: "platycodin D exposure" EXACT []
is_a: ECTO:9000436 ! exposure to glycoside
is_a: ECTO:9002364 ! exposure to terpenoid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:70436 ! has exposure stimulus platycodin D
relationship: RO:0002309 CHEBI:70436 ! has exposure stimulus platycodin D

[Term]
id: ECTO:9002868
name: exposure to prednisone
def: "An exposure to prednisone." []
synonym: "prednisone exposure" EXACT []
is_a: ECTO:0000259 ! exposure to glucocorticoid
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8382 ! has exposure stimulus prednisone
relationship: RO:0002309 CHEBI:8382 ! has exposure stimulus prednisone

[Term]
id: ECTO:9002869
name: exposure to prostaglandin D2
def: "An exposure to prostaglandin D2." []
synonym: "prostaglandin D2 exposure" EXACT []
is_a: ECTO:9000317 ! exposure to prostaglandins D
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15555 ! has exposure stimulus prostaglandin D2
relationship: RO:0002309 CHEBI:15555 ! has exposure stimulus prostaglandin D2

[Term]
id: ECTO:9002870
name: exposure to Proteinase K
def: "An exposure to Proteinase K." []
synonym: "Proteinase K exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:201492 ! has exposure stimulus Proteinase K
relationship: RO:0002309 CHEBI:201492 ! has exposure stimulus Proteinase K

[Term]
id: ECTO:9002871
name: exposure to pyrazolopyrimidine
def: "An exposure to pyrazolopyrimidine." []
synonym: "pyrazolopyrimidine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:38669 ! has exposure stimulus pyrazolopyrimidine
relationship: RO:0002309 CHEBI:38669 ! has exposure stimulus pyrazolopyrimidine

[Term]
id: ECTO:9002872
name: exposure to pyrimethamine
def: "An exposure to pyrimethamine." []
synonym: "pyrimethamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:8673 ! has exposure stimulus pyrimethamine
relationship: RO:0002309 CHEBI:8673 ! has exposure stimulus pyrimethamine

[Term]
id: ECTO:9002873
name: exposure to queuine
def: "An exposure to queuine." []
synonym: "queuine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17433 ! has exposure stimulus queuine
relationship: RO:0002309 CHEBI:17433 ! has exposure stimulus queuine

[Term]
id: ECTO:9002874
name: exposure to Y-27632
def: "An exposure to Y-27632." []
synonym: "Y-27632 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:75393 ! has exposure stimulus Y-27632
relationship: RO:0002309 CHEBI:75393 ! has exposure stimulus Y-27632

[Term]
id: ECTO:9002875
name: exposure to JTE-013
def: "An exposure to JTE-013." []
synonym: "JTE-013 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:195541 ! has exposure stimulus JTE-013
relationship: RO:0002309 CHEBI:195541 ! has exposure stimulus JTE-013

[Term]
id: ECTO:9002876
name: exposure to sarcosine
def: "An exposure to sarcosine." []
synonym: "sarcosine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:15611 ! has exposure stimulus sarcosine
relationship: RO:0002309 CHEBI:15611 ! has exposure stimulus sarcosine

[Term]
id: ECTO:9002877
name: exposure to SCH772984
def: "An exposure to SCH772984." []
synonym: "SCH772984 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:167670 ! has exposure stimulus SCH772984
relationship: RO:0002309 CHEBI:167670 ! has exposure stimulus SCH772984

[Term]
id: ECTO:9002878
name: exposure to Schisantherin A
def: "An exposure to Schisantherin A." []
synonym: "Schisantherin A exposure" EXACT []
is_a: ECTO:9002562 ! exposure to polyphenol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9048 ! has exposure stimulus Schisantherin A
relationship: RO:0002309 CHEBI:9048 ! has exposure stimulus Schisantherin A

[Term]
id: ECTO:9002879
name: exposure to scopolamine
def: "An exposure to scopolamine." []
synonym: "scopolamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000271 ! exposure to alkaloid
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16794 ! has exposure stimulus scopolamine
relationship: RO:0002309 CHEBI:16794 ! has exposure stimulus scopolamine

[Term]
id: ECTO:9002880
name: exposure to short-chain fatty acid
def: "An exposure to short-chain fatty acid." []
synonym: "short-chain fatty acid exposure" EXACT []
is_a: ECTO:9000308 ! exposure to fatty acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26666 ! has exposure stimulus short-chain fatty acid
relationship: RO:0002309 CHEBI:26666 ! has exposure stimulus short-chain fatty acid

[Term]
id: ECTO:9002881
name: exposure to silmitasertib
def: "An exposure to silmitasertib." []
synonym: "silmitasertib exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:232159 ! has exposure stimulus silmitasertib
relationship: RO:0002309 CHEBI:232159 ! has exposure stimulus silmitasertib

[Term]
id: ECTO:9002882
name: exposure to milnacipran
def: "An exposure to milnacipran." []
synonym: "milnacipran exposure" EXACT []
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:135005 ! has exposure stimulus milnacipran
relationship: RO:0002309 CHEBI:135005 ! has exposure stimulus milnacipran

[Term]
id: ECTO:9002883
name: exposure to sodium atom
def: "An exposure to sodium atom." []
synonym: "sodium atom exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:26708 ! has exposure stimulus sodium atom
relationship: RO:0002309 CHEBI:26708 ! has exposure stimulus sodium atom

[Term]
id: ECTO:9002884
name: exposure to spermidine trihydrochloride
def: "An exposure to spermidine trihydrochloride." []
synonym: "spermidine trihydrochloride exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:233088 ! has exposure stimulus spermidine trihydrochloride
relationship: RO:0002309 CHEBI:233088 ! has exposure stimulus spermidine trihydrochloride

[Term]
id: ECTO:9002885
name: exposure to fluvoxamine
def: "An exposure to fluvoxamine." []
synonym: "fluvoxamine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5138 ! has exposure stimulus fluvoxamine
relationship: RO:0002309 CHEBI:5138 ! has exposure stimulus fluvoxamine

[Term]
id: ECTO:9002886
name: exposure to sulfasalazine
def: "An exposure to sulfasalazine." []
synonym: "sulfasalazine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:9334 ! has exposure stimulus sulfasalazine
relationship: RO:0002309 CHEBI:9334 ! has exposure stimulus sulfasalazine

[Term]
id: ECTO:9002887
name: exposure to corticotropin
def: "An exposure to corticotropin." []
synonym: "corticotropin exposure" EXACT []
is_a: ECTO:9000273 ! exposure to peptide hormone
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3892 ! has exposure stimulus corticotropin
relationship: RO:0002309 CHEBI:3892 ! has exposure stimulus corticotropin

[Term]
id: ECTO:9002888
name: exposure to tafenoquine
def: "An exposure to tafenoquine." []
synonym: "tafenoquine exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:135752 ! has exposure stimulus tafenoquine
relationship: RO:0002309 CHEBI:135752 ! has exposure stimulus tafenoquine

[Term]
id: ECTO:9002889
name: exposure to taurocholic acid
def: "An exposure to taurocholic acid." []
synonym: "taurocholic acid exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:28865 ! has exposure stimulus taurocholic acid
relationship: RO:0002309 CHEBI:28865 ! has exposure stimulus taurocholic acid

[Term]
id: ECTO:9002890
name: exposure to teriparatide
def: "An exposure to teriparatide." []
synonym: "teriparatide exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:135983 ! has exposure stimulus teriparatide
relationship: RO:0002309 CHEBI:135983 ! has exposure stimulus teriparatide

[Term]
id: ECTO:9002891
name: exposure to bendroflumethiazide
def: "An exposure to bendroflumethiazide." []
synonym: "bendroflumethiazide exposure" EXACT []
is_a: ECTO:9001359 ! exposure to sulfonamide
is_a: ECTO:9002635 ! exposure to thiazide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:3013 ! has exposure stimulus bendroflumethiazide
relationship: RO:0002309 CHEBI:3013 ! has exposure stimulus bendroflumethiazide

[Term]
id: ECTO:9002892
name: exposure to indapamide
def: "An exposure to indapamide." []
synonym: "indapamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:5893 ! has exposure stimulus indapamide
relationship: RO:0002309 CHEBI:5893 ! has exposure stimulus indapamide

[Term]
id: ECTO:9002893
name: exposure to cannabidiol
def: "An exposure to cannabidiol." []
synonym: "cannabidiol exposure" EXACT []
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:69478 ! has exposure stimulus cannabidiol
relationship: RO:0002309 CHEBI:69478 ! has exposure stimulus cannabidiol

[Term]
id: ECTO:9002894
name: exposure to treprostinil
def: "An exposure to treprostinil." []
synonym: "treprostinil exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:50861 ! has exposure stimulus treprostinil
relationship: RO:0002309 CHEBI:50861 ! has exposure stimulus treprostinil

[Term]
id: ECTO:9002895
name: exposure to tryptophan
def: "An exposure to tryptophan." []
synonym: "tryptophan exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27897 ! has exposure stimulus tryptophan
relationship: RO:0002309 CHEBI:27897 ! has exposure stimulus tryptophan

[Term]
id: ECTO:9002896
name: exposure to tryptophol
def: "An exposure to tryptophol." []
synonym: "tryptophol exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001334 ! exposure to primary alcohol
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:17890 ! has exposure stimulus tryptophol
relationship: RO:0002309 CHEBI:17890 ! has exposure stimulus tryptophol

[Term]
id: ECTO:9002897
name: exposure to tauroursodeoxycholic acid
def: "An exposure to tauroursodeoxycholic acid." []
synonym: "tauroursodeoxycholic acid exposure" EXACT []
is_a: ECTO:0002002 ! exposure to steroid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:80774 ! has exposure stimulus tauroursodeoxycholic acid
relationship: RO:0002309 CHEBI:80774 ! has exposure stimulus tauroursodeoxycholic acid

[Term]
id: ECTO:9002899
name: exposure to Tyr-Asp
def: "An exposure to Tyr-Asp." []
synonym: "Tyr-Asp exposure" EXACT []
is_a: ECTO:9000402 ! exposure to peptide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:141455 ! has exposure stimulus Tyr-Asp
relationship: RO:0002309 CHEBI:141455 ! has exposure stimulus Tyr-Asp

[Term]
id: ECTO:9002900
name: exposure to uridine
def: "An exposure to uridine." []
synonym: "uridine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:16704 ! has exposure stimulus uridine
relationship: RO:0002309 CHEBI:16704 ! has exposure stimulus uridine

[Term]
id: ECTO:9002901
name: exposure to valine
def: "An exposure to valine." []
synonym: "valine exposure" EXACT []
is_a: ECTO:9000268 ! exposure to amino acid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:27266 ! has exposure stimulus valine
relationship: RO:0002309 CHEBI:27266 ! has exposure stimulus valine

[Term]
id: ECTO:9002902
name: exposure to varenicline
def: "An exposure to varenicline." []
synonym: "varenicline exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:84500 ! has exposure stimulus varenicline
relationship: RO:0002309 CHEBI:84500 ! has exposure stimulus varenicline

[Term]
id: ECTO:9002903
name: exposure to AN11736
def: "An exposure to AN11736." []
synonym: "AN11736 exposure" EXACT []
is_a: ECTO:9000173 ! exposure to boron
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000533 ! exposure to organofluorine compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:157671 ! has exposure stimulus AN11736
relationship: RO:0002309 CHEBI:157671 ! has exposure stimulus AN11736

[Term]
id: ECTO:9002904
name: exposure to virginiamycin
def: "An exposure to virginiamycin." []
synonym: "virginiamycin exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:87209 ! has exposure stimulus virginiamycin
relationship: RO:0002309 CHEBI:87209 ! has exposure stimulus virginiamycin

[Term]
id: ECTO:9002905
name: exposure to willow bark extract
def: "An exposure to willow bark extract." []
synonym: "willow bark extract exposure" EXACT []
is_a: ECTO:0000231 ! exposure to chemical
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:79395 ! has exposure stimulus willow bark extract
relationship: RO:0002309 CHEBI:79395 ! has exposure stimulus willow bark extract

[Term]
id: ECTO:9002906
name: exposure to pirinixic acid
def: "An exposure to pirinixic acid." []
synonym: "pirinixic acid exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9002815 ! exposure to sulfide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:32509 ! has exposure stimulus pirinixic acid
relationship: RO:0002309 CHEBI:32509 ! has exposure stimulus pirinixic acid

[Term]
id: ECTO:9002907
name: exposure to YK-4-279
def: "An exposure to YK-4-279." []
synonym: "YK-4-279 exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0001152 ! exposure to organochlorine compound
is_a: ECTO:9000026 ! exposure to alcohol
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9000278 ! exposure to ether
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:94301 ! has exposure stimulus YK-4-279
relationship: RO:0002309 CHEBI:94301 ! has exposure stimulus YK-4-279

[Term]
id: ECTO:9002908
name: exposure to yohimbine
def: "An exposure to yohimbine." []
synonym: "yohimbine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000271 ! exposure to alkaloid
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10093 ! has exposure stimulus yohimbine
relationship: RO:0002309 CHEBI:10093 ! has exposure stimulus yohimbine

[Term]
id: ECTO:9002909
name: exposure to Pervanadate
def: "An exposure to Pervanadate." []
synonym: "Pervanadate exposure" EXACT []
is_a: ECTO:0000135 ! exposure to organic compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:235319 ! has exposure stimulus Pervanadate
relationship: RO:0002309 CHEBI:235319 ! has exposure stimulus Pervanadate

[Term]
id: ECTO:9002910
name: exposure to zebularine
def: "An exposure to zebularine." []
synonym: "zebularine exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:46938 ! has exposure stimulus zebularine
relationship: RO:0002309 CHEBI:46938 ! has exposure stimulus zebularine

[Term]
id: ECTO:9002911
name: exposure to zileuton
def: "An exposure to zileuton." []
synonym: "zileuton exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:9000404 ! exposure to nitrogen
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10112 ! has exposure stimulus zileuton
relationship: RO:0002309 CHEBI:10112 ! has exposure stimulus zileuton

[Term]
id: ECTO:9002912
name: exposure to zingerone
def: "An exposure to zingerone." []
synonym: "zingerone exposure" EXACT []
is_a: ECTO:9000044 ! exposure to ketone
is_a: ECTO:9000278 ! exposure to ether
is_a: ECTO:9001353 ! exposure to phenols
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:68657 ! has exposure stimulus zingerone
relationship: RO:0002309 CHEBI:68657 ! has exposure stimulus zingerone

[Term]
id: ECTO:9002913
name: exposure to zonisamide
def: "An exposure to zonisamide." []
synonym: "zonisamide exposure" EXACT []
is_a: ECTO:0000163 ! exposure to organic cyclic compound
is_a: ECTO:0000371 ! exposure to oxygen molecular entity
is_a: ECTO:9000190 ! exposure to organonitrogen compound
is_a: ECTO:9001359 ! exposure to sulfonamide
intersection_of: ExO:0000002 ! exposure event
intersection_of: RO:0002309 CHEBI:10127 ! has exposure stimulus zonisamide
relationship: RO:0002309 CHEBI:10127 ! has exposure stimulus zonisamide

[Term]
id: ENVO:00000000
name: geographic feature
def: "An astrononmical body part which delimited by physical discontinuities with its surroundings." []
comment: This class is being depopulated and will be filled only with inferred subclasses. Please do not use this for direct annotation, favouring instead a more descriptive subclass.
synonym: "macroscopic spatial feature" EXACT []
xref: https://en.wikipedia.org/wiki/Geographic_feature
is_a: ENVO:01000813 ! astronomical body part

[Term]
id: ENVO:00000002
name: anthropogenic geographic feature
def: "An anthropogenic geographic feature is a geographic feature resulting from the influence of human beings on nature." [ORCID:0000-0002-4366-3088]
xref: FTT:78
xref: TGN:50001
is_a: ENVO:00000000 ! geographic feature
intersection_of: ENVO:00000000 ! geographic feature
intersection_of: RO:0002354 ENVO:01000952 ! formed as result of anthropisation
relationship: RO:0002354 ENVO:01000952 ! formed as result of anthropisation

[Term]
id: ENVO:00000003
name: mine tailing
def: "Mine tailings are the materials left over after the process of separating the valuable fraction from the uneconomic fraction (gangue) of an ore." [https://en.wikipedia.org/wiki/Tailings]
xref: FTT:625
xref: FTT:631
is_a: ENVO:0010001 ! anthropogenic environmental material

[Term]
id: ENVO:00000010
name: transport feature
def: "A construction which enables the movement of humans, their animals or their vehicles." [MA:ma]
xref: FTT:83
is_a: ENVO:00000070 ! human construction
relationship: RO:0000056 ENVO:01001444 ! participates in usage of an environment for transportation

[Term]
id: ENVO:00000011
name: garden
def: "An enclosure for displaying selected plant or animal life." [Geonames:feature]
xref: FTT:31
xref: FTT:743
xref: Geonames:S.GDN
xref: https://en.wikipedia.org/wiki/Garden
xref: TGN:53010
is_a: ENVO:00000002 ! anthropogenic geographic feature

[Term]
id: ENVO:00000012
name: hydrographic feature
def: "A geographical feature associated with water." [MA:ma]
xref: FTT:131
xref: FTT:280
xref: FTT:711
xref: FTT:761
xref: FTT:824
xref: FTT:825
xref: FTT:826
xref: FTT:827
xref: FTT:828
xref: FTT:829
xref: Geonames:H.OVF
is_a: ENVO:00000000 ! geographic feature
is_a: RO:0002577 ! system
relationship: RO:0002507 ENVO:00000063 ! determined by water body

[Term]
id: ENVO:00000015
name: ocean
def: "A marine water body which is constitutes the majority of an astronomical body's hydrosphere." []
xref: EcoLexicon:ocean
xref: FTT:1019
xref: FTT:943
xref: Geonames:H.OCN
xref: https://en.wikipedia.org/wiki/Ocean
xref: LTER:695 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=695&/oceans"}
xref: SWEETRealm:Ocean
xref: TGN:21102
is_a: ENVO:00001999 ! marine water body
is_a: ENVO:01001319 ! saline water body
relationship: RO:0002473 ENVO:00002149 ! composed primarily of sea water

[Term]
id: ENVO:00000016
name: sea
def: "A large expanse of saline water usually connected with an ocean." [https://en.wikipedia.org/wiki/Sea]
xref: EcoLexicon:sea
xref: FTT:233
xref: FTT:830
xref: Geonames:H.SEA
xref: https://en.wikipedia.org/wiki/Sea
xref: TGN:21103
is_a: ENVO:00001999 ! marine water body
is_a: ENVO:01001319 ! saline water body
relationship: RO:0002473 ENVO:00002149 ! composed primarily of sea water

[Term]
id: ENVO:00000017
name: saline hydrographic feature
def: "A geographical feature associated with water with a halinity above 30 ppt (roughly 35 g/L)." [https://en.wikipedia.org/wiki/Salinity]
is_a: ENVO:00000012 ! hydrographic feature

[Term]
id: ENVO:00000019
name: saline lake
def: "A lake whose water contains a considerable concentration of dissolved salts." [MA:ma]
synonym: "salt lake" EXACT [USGS:SDTS]
xref: FTT:221
xref: FTT:907
xref: Geonames:H.LKN
xref: Geonames:H.LKSN
xref: https://en.wikipedia.org/wiki/Saline_lake
xref: TGN:21116
is_a: ENVO:00000020 ! lake
is_a: ENVO:01001319 ! saline water body
intersection_of: ENVO:00000020 ! lake
intersection_of: RO:0002473 ENVO:00002010 ! composed primarily of saline water

[Term]
id: ENVO:00000020
name: lake
def: "A body of water or other liquid of considerable size contained in a depression on a landmass." [https://en.wikipedia.org/wiki/Lake]
xref: EcoLexicon:lake
xref: FTT:221
xref: FTT:704
xref: FTT:909
xref: Geonames:H.LK
xref: Geonames:H.LKS
xref: LTER:278 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=278&/lakes"}
xref: SPIRE:Lake_or_pond
xref: SWEETRealm:Lake
xref: TGN:21114
xref: TGN:21115
is_a: ENVO:01000617 ! lentic water body
relationship: ENVO:01001307 ENVO:01001782 ! partially_surrounded_by landmass
relationship: RO:0001025 ENVO:00000309 ! located in depressed landform

[Term]
id: ENVO:00000022
name: river
def: "A stream which, through permanent or seasonal flow processes, moves from elevated land towards lower elevations through a definite channel and empties either into a sea, lake, or another river or ends on land as bed seepage and evapotranspiration exceed water supply." [ADL:FTT, https://orcid.org/0000-0002-4366-3088] {comment="https://en.wikipedia.org/wiki/River"}
comment: "There are no official definitions for the generic term river as applied to geographic features, although in some countries or communities a stream is defined by its size. Many names for small rivers are specific to geographic location; examples are "run" in some parts of the United States, "burn" in Scotland and northeast England, and "beck" in northern England. Sometimes a river is defined as being larger than a creek, but not always: the language is vague." {comment="https://en.wikipedia.org/wiki/River"}
synonym: "rio" EXACT [ADL:FTT, USGS:SDTS]
xref: EcoLexicon:river
xref: FTT:1179
xref: FTT:251
xref: LTER:474 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=474&/rivers"}
xref: SPIRE:River
xref: SWEETRealm:River
xref: TGN:21105
is_a: ENVO:00000023 ! stream
relationship: RO:0002150 ENVO:01000652 ! continuous with river channel
relationship: RO:0002220 ENVO:00000143 ! adjacent to river bank

[Term]
id: ENVO:00000023
name: stream
def: "A watercourse which is linear and flows across the solid portion of a planetary surface." [USGS:http\://mapping.usgs.gov/www/ti/GNIS/gnis_users_guide_appendixc.html]
synonym: "streams" EXACT [Geonames:feature]
xref: EcoLexicon:stream
xref: FTT:105
xref: FTT:1221
xref: FTT:1225
xref: FTT:1261
xref: FTT:303
xref: FTT:371
xref: FTT:593
xref: FTT:721
xref: Geonames:H.STM
xref: Geonames:H.STMS
xref: https://en.wikipedia.org/wiki/Stream
xref: LTER:562 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=562&/streams"}
xref: SWEETRealm:Stream
xref: TGN:21106
xref: TGN:21107
xref: TGN:21108
xref: TGN:21109
is_a: ENVO:00000029 ! watercourse
relationship: RO:0000086 PATO:0001199 ! has quality linear
relationship: RO:0002150 ENVO:01000650 ! continuous with stream channel

[Term]
id: ENVO:00000029
name: watercourse
def: "A flowing body of water." [https://en.wikipedia.org/wiki/Watercourse]
xref: EcoLexicon:brook
xref: EcoLexicon:course
xref: EcoLexicon:culvert
xref: EcoLexicon:gully
xref: EcoLexicon:ravine
xref: EcoLexicon:spillway
xref: EcoLexicon:waterway
xref: FTT:105
xref: Geonames:H.NRWS
xref: Geonames:H.RCH
xref: Geonames:H.WTRC
xref: Geonames:S.SPLY
xref: https://en.wikipedia.org/wiki/Watercourse
xref: TGN:21110
xref: TGN:21131
xref: TGN:21133
xref: TGN:21137
xref: TGN:21163
xref: TGN:21499
is_a: ENVO:01000618 ! lotic water body
relationship: RO:0002150 ENVO:00000395 ! continuous with channel of a watercourse

[Term]
id: ENVO:00000033
name: pond
def: "A body of water, usually of smaller size than a lake." [MA:ma]
synonym: "Pond" EXACT [NASA:earthrealm]
xref: EcoLexicon:pond
xref: FTT:221
xref: FTT:902
xref: FTT:904
xref: FTT:905
xref: Geonames:H.PND
xref: Geonames:H.PNDS
xref: Geonames:H.POOL
xref: https://en.wikipedia.org/wiki/Pond
xref: LTER:975 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=975&/ponds"}
xref: SPIRE:Lake_or_pond
xref: SWEETRealm:Pond
xref: TGN:21104
xref: TGN:21119
is_a: ENVO:01000617 ! lentic water body

[Term]
id: ENVO:00000043
name: wetland area
def: "An vegetated area which overlaps a wetland ecosystem." [https://en.wikipedia.org/wiki/Wetland]
is_a: ENVO:01001305 ! vegetated area
intersection_of: ENVO:01001305 ! vegetated area
intersection_of: RO:0002131 ENVO:01001209 ! overlaps wetland ecosystem
relationship: RO:0002131 ENVO:01001209 ! overlaps wetland ecosystem

[Term]
id: ENVO:00000045
name: estuary
def: "A semi-enclosed coastal body of water with one or more rivers or streams flowing into it, and with a free connection to the open sea." [https://en.wikipedia.org/wiki/Estuary]
xref: EcoLexicon:estuary
xref: FTT:234
xref: Geonames:H.ESTY
xref: https://en.wikipedia.org/wiki/Estuary
xref: LTER:182 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=182&/estuaries"}
xref: SWEETRealm:Estuary
xref: TGN:21152
is_a: ENVO:00000063 ! water body
relationship: RO:0002151 ENVO:00000230 ! partially overlaps coastal wetland ecosystem
relationship: RO:0002151 ENVO:00000385 {minCardinality="1"} ! partially overlaps stream mouth
relationship: RO:0002151 ENVO:00000385 ! partially overlaps stream mouth

[Term]
id: ENVO:00000063
name: water body
def: "An accumulation of water of varying size." [https://en.wikipedia.org/wiki/Body_of_water]
comment: The term body of water most often refers to large accumulations of water, such as oceans, seas, and lakes, but it includes smaller pools of water such as ponds, wetlands, or more rarely, puddles. A body of water does not have to be still or contained; Rivers, streams, canals, and other geographical features where water moves from one place to another are also considered bodies of water.
synonym: "aquatic feature" EXACT []
synonym: "bodies of water" EXACT [Getty:TGN]
synonym: "body of water" EXACT [ADL:FTT, Getty:TGN]
synonym: "waterbody" EXACT []
xref: EcoLexicon:waterbody
xref: FTT:131
xref: FTT:280
xref: FTT:827
xref: https://en.wikipedia.org/wiki/Water_body
xref: SWEETRealm:BodyOfWater
xref: TGN:21100
xref: TGN:21101
is_a: ENVO:01000685 ! water mass
relationship: BFO:0000050 ENVO:01000819 ! part of hydrosphere
relationship: RO:0002354 ENVO:01001220 ! formed as result of water accumulation process
relationship: RO:0002473 CHEBI:15377 ! composed primarily of water

[Term]
id: ENVO:00000070
name: human construction
def: "A construction that has been assembled by deliberate human effort." [MA:ma]
synonym: "constructed feature" EXACT []
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01001813 ! construction
intersection_of: BFO:0000040 ! material entity
intersection_of: RO:0002353 ENVO:01000996 ! output of human-directed construction process
relationship: BFO:0000050 ENVO:01000983 ! part of technosphere
relationship: RO:0002353 ENVO:01000996 ! output of human-directed construction process

[Term]
id: ENVO:00000073
name: building
def: "A permanent walled and roofed construction." [USGS:SDTS]
xref: FTT:42
xref: Geonames:S.BLDG
xref: https://en.wikipedia.org/wiki/Building
xref: LTER:76
xref: TGN:51011
is_a: ENVO:00000070 ! human construction
relationship: BFO:0000051 ENVO:01000420 ! has part building part

[Term]
id: ENVO:00000076
name: mine
def: "An excavation in the Earth for the purpose of extracting earth materials." [https://en.wikipedia.org/wiki/Mine, USGS:SDTS]
xref: EcoLexicon:mine
xref: FTT:14
xref: FTT:968
xref: Geonames:L.MNA
xref: Geonames:S.MN
xref: TGN:54211
xref: TGN:54212
is_a: ENVO:00000070 ! human construction
relationship: RO:0000056 ENVO:01001437 ! participates in mining

[Term]
id: ENVO:00000077
name: agricultural ecosystem
comment: As with other classes that are "features", the subclasses of this class are being moved to more informative locations. Their relation to agriculture will be modelled by something more akin to a quality or relation to an agricultural process.
xref: FTT:1246
xref: FTT:1247
xref: FTT:44
xref: FTT:45
xref: FTT:46
xref: FTT:48
xref: FTT:50
xref: FTT:51
xref: FTT:52
xref: FTT:57
xref: FTT:60
xref: FTT:62
xref: FTT:63
xref: FTT:64
xref: FTT:72
xref: FTT:74
xref: Geonames:L.AGRC
xref: Geonames:L.RESA
xref: Geonames:S.NSY
xref: TGN:55001
is_a: ENVO:01001828 ! anthropised ecosystem

[Term]
id: ENVO:00000078
name: farm
def: "An area of land which is used for the cultivation of crops or grazing of livestock, including any agricultural constructions therein." [USGS:SDTS]
synonym: "FARM" EXACT [USGS:SDTS]
xref: FTT:45
xref: FTT:58
xref: FTT:59
xref: FTT:69
xref: Geonames:S.FRM
xref: Geonames:S.FRMS
xref: Geonames:S.RNCH
xref: https://en.wikipedia.org/wiki/Farm
xref: TGN:54011
is_a: ENVO:00000077 ! agricultural ecosystem

[Term]
id: ENVO:00000086
name: plain
def: "A region of general uniform slope, comparatively level, and of considerable extent." [USGS:SDTS]
xref: EcoLexicon:plain
xref: FTT:707
xref: FTT:874
xref: FTT:926
xref: Geonames:T.PLN
xref: https://en.wikipedia.org/wiki/Plain
xref: SWEETRealm:Plain
xref: TGN:21461
is_a: ENVO:01001884 ! surface landform
relationship: RO:0000086 PATO:0000407 ! has quality flat

[Term]
id: ENVO:00000090
name: coastal plain
def: "An area of flat, low-lying land adjacent to a coast and separated from the interior by other features." [https://en.wikipedia.org/wiki/Coastal_plain]
xref: EcoLexicon:coastal_plain
xref: EcoLexicon:coastal_zone
xref: FTT:240
xref: FTT:499
xref: FTT:500
xref: FTT:501
xref: FTT:502
xref: FTT:503
xref: FTT:504
xref: https://en.wikipedia.org/wiki/Coastal_plain
xref: SWEETRealm:CoastalPlain
is_a: ENVO:00000086 ! plain
intersection_of: ENVO:00000086 ! plain
intersection_of: RO:0002131 ENVO:00000303 ! overlaps sea coast
relationship: RO:0002131 ENVO:00000303 ! overlaps sea coast

[Term]
id: ENVO:00000094
name: volcanic feature
def: "A part of an astronomical body associated with a volcano - an opening, or rupture, in that body's surface or crust - which allows hot, molten rock, ash and gases to escape from deep below the surface." [https://en.wikipedia.org/wiki/Volcano]
xref: FTT:591
xref: TGN:21407
is_a: ENVO:01001884 ! surface landform
intersection_of: ENVO:01001884 ! surface landform
intersection_of: RO:0002354 ENVO:01000634 ! formed as result of volcanic eruption
relationship: RO:0002354 ENVO:01000634 ! formed as result of volcanic eruption

[Term]
id: ENVO:00000097
name: desert area
def: "A region rendered barren or partially barren by environmental extremes, especially by low rainfall." [USGS:SDTS]
xref: EcoLexicon:desert
xref: FTT:1
xref: FTT:188
xref: Geonames:T.DSRT
xref: https://en.wikipedia.org/wiki/Desert
xref: LTER:147
xref: SWEETRealm:Desert
xref: TGN:21201
is_a: ENVO:01000752 ! area of barren land
intersection_of: ENVO:01000752 ! area of barren land
intersection_of: RO:0000086 ENVO:01000230 ! has quality arid
relationship: RO:0000086 ENVO:01000230 ! has quality arid

[Term]
id: ENVO:00000106
name: grassland area
def: "An area in which grasses (Graminae) are a significant component of the vegetation." [https://en.wikipedia.org/wiki/Grassland]
is_a: ENVO:01001305 ! vegetated area
relationship: RO:0002131 ENVO:01001206 ! overlaps grassland ecosystem

[Term]
id: ENVO:00000109
name: woodland area
def: "Land having a cover of trees, shrubs, or both." [USGS:SDTS]
xref: FTT:1083
xref: FTT:505
xref: FTT:506
xref: FTT:719
xref: FTT:774
xref: Geonames:V.GRVPN
xref: https://en.wikipedia.org/wiki/Woodland
xref: LTER:503
xref: SWEETRealm:Break
xref: SWEETRealm:Scrub
xref: TGN:21631
xref: TGN:21632
xref: TGN:21641
is_a: ENVO:01001305 ! vegetated area

[Term]
id: ENVO:00000111
name: forested area
def: "An area with a high density of trees. A small forest may be called a wood." [https://en.wikipedia.org/wiki/Forest]
comment: The definitions of forest can vary greatly, and different classes will be needed to support the major categories. Tree cover alone is not enough to distinguish between forests and plantations. The international definition proposed by the 2010 FAO Forestry Resource Assessment: "land spanning more than 0.5 ha with trees higher than 5 metres and canopy cover of more than 10 percent, or trees able to reach these thresholds in situ . It does not include land that is predominantly under agricultural or urban land use." - FAO.  2010. Global forest resources assessment 2010, Main report, FAO Forestry Paper 163. Rome.
xref: EcoLexicon:forest
xref: FTT:258
xref: FTT:506
xref: FTT:715
xref: FTT:717
xref: Geonames:V.FRST
xref: https://en.wikipedia.org/wiki/Forest
xref: LTER:2
xref: SWEETRealm:Forest
xref: TGN:21641
xref: TGN:21642
xref: TGN:21645
is_a: ENVO:00000109 ! woodland area
intersection_of: ENVO:00000109 ! woodland area
intersection_of: RO:0002131 ENVO:01001243 ! overlaps forest ecosystem
relationship: RO:0002131 ENVO:01001243 ! overlaps forest ecosystem

[Term]
id: ENVO:00000114
name: agricultural field
def: "A field which is located on land and used for agricultural purposes, such as the grazing of livestock or the cultivation of crops." [https://en.wikipedia.org/wiki/Field_%28agriculture%29]
xref: EcoLexicon:field
xref: FTT:45
xref: FTT:61
xref: Geonames:L.FLD
xref: SWEETRealm:Field
xref: TGN:21456
is_a: ENVO:01000352 ! field

[Term]
id: ENVO:00000116
name: vineyard
def: "A place where grapes are grown for making wine, raisins or table grapes." [https://en.wikipedia.org/wiki/Vineyard]
synonym: "vineyards" EXACT [Geonames:feature]
xref: FTT:45
xref: FTT:77
xref: Geonames:V.VIN
xref: Geonames:V.VINS
xref: https://en.wikipedia.org/wiki/Vineyard
xref: TGN:54015
is_a: ENVO:00000117 ! plantation

[Term]
id: ENVO:00000117
name: plantation
def: "An intentional planting of a crop, on a large scale, usually for uses other than cereal production or pasture. The term is currently most often used for plantings of trees and shrubs. The term tends also to be used for plantings maintained on economic bases other than that of subsistence farming." [https://en.wikipedia.org/wiki/Plantation]
xref: FTT:45
xref: FTT:68
xref: https://en.wikipedia.org/wiki/Plantation
xref: TGN:54041
is_a: ENVO:00000078 ! farm
is_a: ENVO:01000813 ! astronomical body part
relationship: BFO:0000050 ENVO:01000245 ! part of cropland biome

[Term]
id: ENVO:00000134
name: permafrost
def: "An environmental material which is 1) composed primarily of soil or rock and included ice or organic material and 2) at or below the freezing point of water for two or more years." [https://en.wikipedia.org/wiki/Permafrost, https://orcid.org/0000-0003-4808-4736]
comment: Ice is not always present, as may be in the case of nonporous bedrock, but it frequently occurs and it may be in amounts exceeding the potential hydraulic saturation of the ground material.
xref: http://sweetontology.net/realmSoil/Permafrost
xref: https://en.wikipedia.org/wiki/Permafrost
xref: LTER:408
is_a: ENVO:00010483 ! environmental material
relationship: RO:0000086 PATO:0001306 ! has quality decreased temperature

[Term]
id: ENVO:00000141
name: bank
def: "The sloping margin of a watercourse, serving to confine it to its natural channel." [MA:ma]
xref: EcoLexicon:bank
xref: FTT:195
xref: SWEETRealm:Bank
xref: TGN:21466
is_a: ENVO:00002000 ! slope
relationship: BFO:0000050 ENVO:00000395 ! part of channel of a watercourse

[Term]
id: ENVO:00000142
name: stream bank
def: "The sloping margin of a stream, serving to confine it to its natural channel." [MA:ma]
xref: FTT:195
xref: FTT:196
xref: Geonames:H.BNKR
xref: https://en.wikipedia.org/wiki/Stream_bank
is_a: ENVO:00000141 ! bank

[Term]
id: ENVO:00000143
name: river bank
def: "The sloping margin of a river, serving to confine it to its natural channel." [MA:ma]
synonym: "riverbank" EXACT [Getty:TGN]
xref: https://en.wikipedia.org/wiki/River_bank
xref: TGN:21155
is_a: ENVO:00000142 ! stream bank

[Term]
id: ENVO:00000176
name: elevated landform
def: "A landform elevated above the surrounding area." [MA:ma]
xref: https://en.wikipedia.org/wiki/Elevation
xref: LTER:177
xref: SWEETRealm:Elevation
is_a: ENVO:01001886 ! landform
intersection_of: ENVO:01001886 ! landform
intersection_of: RO:0000086 PATO:0001688 ! has quality increased elevation
relationship: BFO:0000051 ENVO:00002000 ! has part slope
relationship: RO:0000086 PATO:0001688 ! has quality increased elevation

[Term]
id: ENVO:00000191
name: solid astronomical body part
def: "A part of an astronomical body which is primarily composed of solid material." [https://en.wikipedia.org/wiki/Landform]
xref: EcoLexicon:landform
xref: EcoLexicon:landforms
xref: FTT:754
xref: FTT:96
xref: SWEETRealm:Landform
xref: TGN:21400
xref: TGN:21401
is_a: ENVO:01001784 ! compound astronomical body part
intersection_of: ENVO:01000813 ! astronomical body part
intersection_of: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material
relationship: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material

[Term]
id: ENVO:00000194
name: scree
def: "Broken rock that appears at the bottom of crags, mountain cliffs or valley shoulders." [https://en.wikipedia.org/wiki/Scree]
xref: EcoLexicon:scree
xref: FTT:1078
xref: FTT:96
xref: Geonames:T.TAL
xref: https://en.wikipedia.org/wiki/Scree
xref: SWEETRealm:Talus
xref: TGN:21508
is_a: ENVO:01000814 ! solid environmental material
relationship: BFO:0000051 ENVO:00000339 ! has part piece of rock
relationship: RO:0001000 ENVO:00001995 ! derives from rock

[Term]
id: ENVO:00000230
name: coastal wetland ecosystem
def: "A wetland ecosystem which overlaps both terrestrial and marine ecosystems." [MA:ma]
xref: https://en.wikipedia.org/wiki/Coastal_wetland
is_a: ENVO:01001209 ! wetland ecosystem
intersection_of: ENVO:01001209 ! wetland ecosystem
intersection_of: RO:0002131 ENVO:00000303 ! overlaps sea coast
relationship: RO:0002131 ENVO:00000303 ! overlaps sea coast

[Term]
id: ENVO:00000243
name: freshwater wetland ecosystem
def: "A wetland which is inundated with water that contains low concentrations of salts." [MA:ma]
is_a: ENVO:01001209 ! wetland ecosystem
relationship: BFO:0000051 ENVO:00000063 ! has part water body
relationship: RO:0002473 ENVO:00002011 ! composed primarily of fresh water

[Term]
id: ENVO:00000247
name: volcano
def: "An opening, or rupture, in the Earth's surface or crust, which allows hot, molten rock, ash and gases to escape from deep below the surface." [https://en.wikipedia.org/wiki/Volcano]
xref: EcoLexicon:volcano
xref: FTT:592
xref: Geonames:T.VLC
xref: https://en.wikipedia.org/wiki/Volcano
xref: TGN:21406
is_a: ENVO:01000667 ! geological fracture
relationship: RO:0002354 ENVO:01000634 ! formed as result of volcanic eruption

[Term]
id: ENVO:00000300
name: scrubland area
def: "Area covered with low-growing or stunted perennial vegetation and usually not mixed with trees." [ADL:FTT]
synonym: "scrubland" EXACT [Geonames:feature]
xref: FTT:1191
xref: FTT:262
xref: FTT:374
xref: FTT:473
xref: FTT:792
xref: FTT:991
xref: Geonames:V.SCRB
xref: https://en.wikipedia.org/wiki/Scrubland
xref: SWEETRealm:Scrub
xref: TGN:21644
xref: TGN:21652
is_a: ENVO:01001305 ! vegetated area

[Term]
id: ENVO:00000303
name: sea coast
def: "The general region of indefinite width that extends from the sea inland to the first major change in terrain features." [USGS:SDTS]
xref: EcoLexicon:coast
xref: EcoLexicon:sea_coast
xref: FTT:500
xref: Geonames:L.CST
xref: https://en.wikipedia.org/wiki/Coast
xref: SPIRE:Coastal
xref: SPIRE:Littoral
xref: SWEETRealm:CoastalRegion
xref: TGN:21483
is_a: ENVO:01000687 ! coast

[Term]
id: ENVO:00000309
name: depressed landform
def: "A landform sunken or depressed below the surrounding area." [https://en.wikipedia.org/wiki/Depression_%28geology%29]
xref: EcoLexicon:depression
xref: FTT:175
xref: FTT:215
xref: FTT:216
xref: Geonames:T.DPR
xref: Geonames:T.PAN
xref: Geonames:T.PANS
xref: SWEETRealm:Depression
xref: TGN:21454
xref: TGN:21497
xref: TGN:21521
is_a: ENVO:01001886 ! landform
intersection_of: ENVO:01001886 ! landform
intersection_of: RO:0000086 PATO:0001689 ! has quality decreased elevation
relationship: BFO:0000051 ENVO:00002000 ! has part slope
relationship: RO:0000086 PATO:0001689 ! has quality decreased elevation
relationship: RO:0000086 PATO:0002143 ! has quality sloped downward

[Term]
id: ENVO:00000328
name: vadose zone
def: "An interface layer which 1) is primarily composed of solid materials, 2) separates the land surface and phreatic zone, and 3) contains groundwater at atmospheric pressure." [http://wasg.iinet.net.au/terminol.html, https://en.wikipedia.org/wiki/Vadose_zone]
comment: If the vadose zone includes portions of soil, the water contained therein is termed soil moisture. In fine grained soils, capillary action can cause the pores of the soil to be fully saturated above the water table at a pressure less than atmospheric. In such soils, therefore, the unsaturated zone is the upper section of the vadose zone and not identical to it.
synonym: "unsaturated zone" EXACT [https://en.wikipedia.org/wiki/Vadose_zone]
is_a: ENVO:01001275 ! solid layer
is_a: ENVO:01001684 ! interface layer
relationship: BFO:0000051 ENVO:01001004 ! has part groundwater
relationship: RO:0002220 ENVO:00000329 ! adjacent to phreatic zone
relationship: RO:0002220 ENVO:01001785 ! adjacent to land

[Term]
id: ENVO:00000329
name: phreatic zone
def: "A compound astronomical body part which is located beneath the land surface and in which all interstices are filled with water that has a hydraulic head greater than atmospheric pressure due to the weight of overlying groundwater." [http://wasg.iinet.net.au/terminol.html, https://en.wikipedia.org/wiki/Phreatic_zone]
xref: https://en.wikipedia.org/wiki/Phreatic_zone
is_a: ENVO:01001784 ! compound astronomical body part
relationship: BFO:0000051 ENVO:01001004 ! has part groundwater

[Term]
id: ENVO:00000339
name: piece of rock
def: "A mass of solid material which is composed primarily of rock." []
xref: FTT:1010
xref: FTT:145
xref: Geonames:T.RK
xref: Geonames:T.RKS
xref: TGN:21444
is_a: ENVO:01001687 ! mass of solid material
intersection_of: ENVO:01001687 ! mass of solid material
intersection_of: RO:0002473 ENVO:00001995 ! composed primarily of rock
relationship: RO:0002473 ENVO:00001995 ! composed primarily of rock

[Term]
id: ENVO:00000340
name: particle of sand
def: "A particle which 1) is composed primarily of and derived from rock or mineral sources and 2) is or was part of a portion of sand." [https://en.wikipedia.org/wiki/Sand]
comment: In general, sand grains are larger than those of silt, but finer than those of gravel.
synonym: "grain of sand" EXACT []
synonym: "granule of sand" EXACT []
synonym: "sand granule" EXACT []
is_a: ENVO:01003002 ! particle
disjoint_from: ENVO:01000017 ! sand

[Term]
id: ENVO:00000341
name: piece of gravel
def: "A piece of rock which is between two and 64 millimetres in length along its largest dimension." [https://en.wikipedia.org/wiki/Gravel]
comment: Arguably, this could be placed in the "particle" hierarchy, but is usually considered too large in everyday semantics.
is_a: ENVO:00000339 ! piece of rock

[Term]
id: ENVO:00000343
name: particle of silt
def: "A particle which 1) is primarily composed of quartz or feldspar and 2) is or was part of a portion of silt." []
comment: The distinction between silt and clay varies by discipline. Geologists and soil scientists usually consider the separation to occur at a particle size of 2 μm (clays being finer than silts), sedimentologists often use 4–5 μm, and colloid chemists use 1 μm. Geotechnical engineers distinguish between silts and clays based on the plasticity properties of the soil, as measured by the soils' Atterberg limits. ISO 14688 grades clay particles as being smaller than 2 μm and silt particles as being larger. Mixtures of sand, silt and less than 40% clay are called loam. {xref="Properties"}
synonym: "grain of silt" EXACT []
synonym: "granule of silt" EXACT []
is_a: ENVO:01003002 ! particle

[Term]
id: ENVO:00000344
name: grain of desert sand
is_a: ENVO:00000191 ! solid astronomical body part
is_a: ENVO:00000340 ! particle of sand
intersection_of: ENVO:00000340 ! particle of sand
intersection_of: BFO:0000050 ENVO:00005800 ! part of desert sand
relationship: BFO:0000050 ENVO:00005800 ! part of desert sand

[Term]
id: ENVO:00000385
name: stream mouth
def: "The place where a stream discharges into a lagoon, lake, or the sea." [Geonames:feature]
xref: FTT:105
xref: FTT:1222
xref: Geonames:H.STMM
is_a: ENVO:00000479 ! mouth
is_a: ENVO:01001308 ! hydroform
intersection_of: ENVO:00000479 ! mouth
intersection_of: BFO:0000050 ENVO:00000023 ! part of stream
relationship: BFO:0000050 ENVO:00000023 ! part of stream

[Term]
id: ENVO:00000386
name: river mouth
def: "The end of a stream where it enters a standing water body such as a lake, sea or ocean." [MA:ma]
xref: https://en.wikipedia.org/wiki/River_mouth
xref: TGN:21156
is_a: ENVO:00000385 ! stream mouth
intersection_of: ENVO:00000479 ! mouth
intersection_of: BFO:0000050 ENVO:00000022 ! part of river
relationship: BFO:0000050 ENVO:00000022 ! part of river

[Term]
id: ENVO:00000395
name: channel of a watercourse
def: "A depressed landform which physically confines a river, slough or ocean strait, and which consists of a bed and banks." [https://en.wikipedia.org/wiki/Channel_%28geography%29]
xref: EcoLexicon:channel
xref: EcoLexicon:sea_channel
xref: FTT:1192
xref: FTT:233
xref: FTT:461
xref: FTT:462
xref: FTT:463
xref: FTT:464
xref: FTT:465
xref: FTT:466
xref: FTT:468
xref: FTT:469
xref: FTT:470
xref: Geonames:H.CHN
xref: Geonames:U.SCNU
xref: Geonames:U.SCSU
xref: SWEETRealm:Channel
xref: TGN:21137
xref: TGN:23451
is_a: ENVO:00000309 ! depressed landform
relationship: BFO:0000051 ENVO:00000141 ! has part bank
relationship: BFO:0000051 ENVO:00000501 ! has part submerged bed

[Term]
id: ENVO:00000397
name: lake channel
def: "A channel of a watercourse which contains lake water." []
xref: FTT:233
xref: FTT:464
xref: Geonames:H.CHNL
xref: TGN:21185
is_a: ENVO:00000395 ! channel of a watercourse
intersection_of: ENVO:00000395 ! channel of a watercourse
intersection_of: RO:0001015 ENVO:00000020 ! location of lake
relationship: RO:0001015 ENVO:00000020 ! location of lake

[Term]
id: ENVO:00000428
name: biome
def: "A biome is an ecosystem which is undergoing climactic ecological succession." [DOI:10.1186/2041-1480-4-43, https://en.wikipedia.org/wiki/Biome]
comment: In this definition, there is an assumption that no major perturbations are occurring or have occurred in a time frame affects the successional dynamics of the ecosystem. A "major" perturbation is one which disrupts the community's ability to restore its (near) equilibrium. Usually, pioneer or early secondary successional processes would be in effect in such scenarios.
synonym: "major habitat type" EXACT [WWF:Biome]
xref: EcoLexicon:biome
xref: LTER:809 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=809&/biomes"}
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01001110 ! ecosystem
intersection_of: ENVO:01001110 ! ecosystem
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession
relationship: BFO:0000050 ENVO:01000817 ! part of biosphere
relationship: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:00000446
name: terrestrial biome
def: "A biome which is  primarily or completely situated on a landmass." [https://en.wikipedia.org/wiki/Biome#Terrestrial_biomes]
xref: LTER:798
xref: SPIRE:Terrestrial
is_a: ENVO:00000428 ! biome
is_a: ENVO:01001790 ! terrestrial ecosystem
intersection_of: ENVO:01001790 ! terrestrial ecosystem
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:00000447
name: marine biome
def: "An aquatic biome which is determined by a marine water body." [https://en.wikipedia.org/wiki/Ocean, https://orcid.org/0000-0002-4366-3088, ISBN:978-0-618-45504-1, MA:ma]
comment: This biome includes open-ocean and unprotected coastal ecosystems, characterized by exposure to wave action, tidal fluctuation, and ocean currents as well as systems that largely resemble these. Water in the marine biome is generally within the salinity range of seawater: 30 to 38 ppt.
xref: SPIRE:Marine
is_a: ENVO:00002030 ! aquatic biome
is_a: ENVO:01001788 ! marine ecosystem
intersection_of: ENVO:00002030 ! aquatic biome
intersection_of: RO:0002507 ENVO:00001999 ! determined by marine water body

[Term]
id: ENVO:00000469
name: research facility
def: "A facility, permanent or temporary, on land, in air, space or water, where scientific research or measurements can be undertaken." [MA:ma]
is_a: ENVO:00000070 ! human construction

[Term]
id: ENVO:00000479
name: mouth
def: "The exit or point of discharge of a stream into another stream, lake or sea." [USGS:SDTS]
synonym: "MOUTH" EXACT [USGS:SDTS]
xref: EcoLexicon:outlet
xref: https://en.wikipedia.org/wiki/Mouth
xref: SWEETRealm:Mouth
is_a: ENVO:00000029 ! watercourse
relationship: RO:0002180 ENVO:00000063 {minCardinality="2"} ! has component water body
relationship: RO:0002180 ENVO:00000063 ! has component water body

[Term]
id: ENVO:00000495
name: tributary
def: "A stream or river which flows into another river (a parent river) or body of water but which may not flow directly into the sea." [https://en.wikipedia.org/wiki/Tributary]
synonym: "affluent" EXACT [ADL:FTT]
xref: EcoLexicon:affluent
xref: FTT:105
xref: FTT:1261
xref: https://en.wikipedia.org/wiki/Tributary
xref: SWEETRealm:Tributary
xref: TGN:21157
is_a: ENVO:00000023 ! stream
intersection_of: ENVO:00000023 ! stream
intersection_of: RO:0002376 ENVO:00000012 ! tributary of hydrographic feature
relationship: RO:0002376 ENVO:00000012 ! tributary of hydrographic feature

[Term]
id: ENVO:00000501
name: submerged bed
def: "The portion of the ground surface which lies below water." [USGS:SDTS]
xref: EcoLexicon:bed
xref: FTT:804
xref: https://en.wikipedia.org/wiki/Stream_bed
xref: SWEETRealm:Bottom
is_a: ENVO:00000191 ! solid astronomical body part
is_a: ENVO:01001311 ! solid surface layer
is_a: ENVO:01001483 ! surface of an astronomical body
relationship: BFO:0000050 ENVO:00000309 ! part of depressed landform
relationship: RO:0002220 ENVO:00000063 ! adjacent to water body

[Term]
id: ENVO:00000541
name: brackish pond
def: "A pond which is composed primarily of brackish water." []
is_a: ENVO:00000033 ! pond
is_a: ENVO:01001321 ! brackish water body
intersection_of: ENVO:00000033 ! pond
intersection_of: RO:0002473 ENVO:00002019 ! composed primarily of brackish water

[Term]
id: ENVO:00000856
name: city
def: "Incorporated populated place." [ADL:FTT]
xref: EcoLexicon:city
xref: FTT:430
xref: FTT:483
xref: FTT:484
xref: FTT:485
xref: https://en.wikipedia.org/wiki/City
xref: SWEETRealm:City
xref: TGN:83020
xref: TGN:83040
xref: TGN:83043
is_a: ENVO:01000658 ! dense settlement

[Term]
id: ENVO:00000873
name: freshwater biome
def: "An aquatic biome which is determined by a body of freshwater." [https://orcid.org/0000-0002-4366-3088, MA:ma]
xref: SPIRE:Freshwater
is_a: ENVO:00002030 ! aquatic biome
is_a: ENVO:01001789 ! freshwater ecosystem

[Term]
id: ENVO:00001995
name: rock
def: "A rock is a naturally occurring solid aggregate of one or more minerals or mineraloids." [https://en.wikipedia.org/wiki/Rock_(geology), MA:ma]
comment: From https://en.wikipedia.org/wiki/ [A mineral] is different from a rock, which can be an aggregate of minerals or non-minerals and does not have a specific chemical composition. The exact definition of a mineral is under debate, especially with respect to the requirement a valid species be abiogenic, and to a lesser extent with regards to it having an ordered atomic structure.
xref: EcoLexicon:rock
xref: FTT:1010
xref: FTT:145
xref: Geonames:T.RK
xref: Geonames:T.RKS
xref: https://en.wikipedia.org/wiki/Rock
xref: SWEETRealm:Rock
xref: TGN:21444
is_a: ENVO:01000814 ! solid environmental material
disjoint_from: ENVO:01000256 ! mineral material
relationship: RO:0000086 PATO:0000386 ! has quality hard

[Term]
id: ENVO:00001996
name: mine drainage
def: "The outflow of water from a mine." [MA:ma]
xref: https://en.wikipedia.org/wiki/Acid_mine_drainage
is_a: ENVO:00000029 ! watercourse
relationship: BFO:0000050 ENVO:00000076 ! part of mine

[Term]
id: ENVO:00001997
name: acid mine drainage
def: "A mine drainage with an acidic pH." [MA:ma]
xref: https://en.wikipedia.org/wiki/Acid_mine_drainage
is_a: ENVO:00001996 ! mine drainage
intersection_of: ENVO:00001996 ! mine drainage
intersection_of: RO:0000086 PATO:0001429 ! has quality acidic
relationship: RO:0000086 PATO:0001429 ! has quality acidic

[Term]
id: ENVO:00001998
name: soil
def: "An environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, interstitial gases, liquids, and a broad range of resident micro- and macroorganisms." [https://en.wikipedia.org/wiki/Soil]
comment: 'In engineering terms, soil is referred to as regolith, or loose rock material that lies above the 'solid geology'. Soil is commonly referred to as "earth" or "dirt"; technically, the term "dirt" should be restricted to displaced soil.' https://en.wikipedia.org/wiki/Soil\n\n" The upper limit of soil is the boundary between soil and air, shallow water, live plants, or plant materials that have not begun to decompose. Areas are not considered to have soil if the surface is permanently covered by water too deep (typically more than 2.5 meters) for the growth of rooted plants.\n\nThe lower boundary that separates soil from the nonsoil underneath is most difficult to define. Soil consists of horizons near the Earth's surface that, in contrast to the underlying parent material, have been altered by the interactions of climate, relief, and living organisms over time. Commonly, soil grades at its lower boundary to hard rock or to earthy materials virtually devoid of animals, roots, or other marks of biological activity. For purposes of classification, the lower boundary of soil is arbitrarily set at 200 cm."  Soil taxonomy, 2nd Ed., quoted in http://www.nrcs.usda.gov/wps/portal/nrcs/detail/soils/edu/?cid=nrcs142p2_054280
xref: https://en.wikipedia.org/wiki/Soil
xref: LTER:535
xref: SPIRE:Soil
xref: SWEETRealm:Soil
is_a: ENVO:00010483 ! environmental material
is_a: ENVO:01000813 ! astronomical body part
relationship: BFO:0000050 ENVO:01000820 ! part of pedosphere
relationship: BFO:0000051 ENVO:00002982 ! has part clay
relationship: BFO:0000051 ENVO:01000016 ! has part silt
relationship: BFO:0000051 ENVO:01000017 ! has part sand
relationship: BFO:0000051 ENVO:01000155 ! has part organic material
relationship: BFO:0000051 ENVO:01000256 ! has part mineral material
relationship: RO:0000086 PATO:0000984 ! has quality porous
relationship: RO:0000091 ENVO:06105304 ! has disposition water-holding capacity of soil

[Term]
id: ENVO:00001999
name: marine water body
def: "A lentic water body which is composed primarily of marine water." []
synonym: "body of marine water" EXACT []
synonym: "marine waterbody" EXACT []
is_a: ENVO:01000617 ! lentic water body

[Term]
id: ENVO:00002000
name: slope
def: "A solid astronomical body part which is part of the planetary surface between the peak of an elevation or the bottom of a depression and relatively flat surrounding land." [MA:ma]
xref: EcoLexicon:slope
xref: https://en.wikipedia.org/wiki/Slope
xref: SWEETRealm:Slope
is_a: ENVO:01001886 ! landform
relationship: RO:0000086 PATO:0001481 ! has quality sloped

[Term]
id: ENVO:00002001
name: waste water
def: "Water that has been adversely affected in quality by anthropogenic influence." [https://en.wikipedia.org/wiki/Wastewater]
xref: EcoLexicon:waste_water
xref: https://en.wikipedia.org/wiki/Waste_water
xref: SWEETRealm:Wastewater
is_a: ENVO:00002186 ! contaminated water
is_a: ENVO:00002264 ! waste material

[Term]
id: ENVO:00002003
name: fecal material
def: "An excreta material which is composed primarily of feces, an excreta consisting of waste products expelled from an animal's digestive tract through the anus (or cloaca) during defecation." [https://en.wikipedia.org/wiki/Feces]
comment: ENVO bodily fluid classes differ from UBERON's treatment of bodily fluids. UBERON refers to the substance itself ("S"). We assert that UBERON's classes are the primary compositional component of the terms in ENVO ("S material"). Use of the ENVO terms is typically recommended when you wish to indicate that there may be other materials intermixed with S.
synonym: "faeces material" EXACT []
synonym: "feces material" EXACT []
xref: EcoLexicon:drop
xref: SPIRE:Dung
xref: SWEETRealm:Drop
is_a: ENVO:02000022 ! excreta material
relationship: RO:0002473 UBERON:0001988 ! composed primarily of feces

[Term]
id: ENVO:00002005
name: air
def: "The mixture of gases (roughly (by molar content/volume: 78% nitrogen, 20.95% oxygen, 0.93% argon, 0.038% carbon dioxide, trace amounts of other gases, and a variable amount (average around 1%) of water vapor) that surrounds the planet Earth." [https://en.wikipedia.org/wiki/Air]
xref: EcoLexicon:air
xref: https://en.wikipedia.org/wiki/Air
xref: LTER:18
xref: SWEETRealm:Air
is_a: ENVO:01000797 ! gaseous environmental material
relationship: BFO:0000051 CHEBI:15379 ! has part dioxygen
relationship: BFO:0000051 CHEBI:16526 ! has part carbon dioxide
relationship: BFO:0000051 CHEBI:36908 ! has part argon molecular entity
relationship: BFO:0000051 ENVO:01000266 ! has part water vapour
relationship: RO:0002473 CHEBI:17997 ! composed primarily of dinitrogen

[Term]
id: ENVO:00002006
name: liquid water
def: "An environmental material primarily composed of dihydrogen oxide in its liquid form." [MA:ma]
xref: EcoLexicon:water
xref: https://en.wikipedia.org/wiki/Water
xref: LTER:617
is_a: ENVO:01000815 ! liquid environmental material
relationship: RO:0002473 CHEBI:15377 ! composed primarily of water

[Term]
id: ENVO:00002007
name: sediment
def: "Particulate environmental material which is formed as a result of the transport and deposition of particles by flowing liquid." [https://en.wikipedia.org/wiki/Sediment]
comment: Sediment is typically deposited on the bed or bottom of a body of water or other liquid.
xref: EcoLexicon:sediment
xref: EcoLexicon:sedimentation
xref: https://en.wikipedia.org/wiki/Sediment
xref: LTER:492
xref: LTER:493
xref: SWEETRealm:Sediment
is_a: ENVO:01000060 ! particulate environmental material
relationship: RO:0000086 PATO:0000984 ! has quality porous

[Term]
id: ENVO:00002008
name: dust
def: "Particulate environmental material with diameters less than 500 micrometers." [https://en.wikipedia.org/wiki/Dust]
comment: Dust occurs in and may be deposited from the atmosphere.
xref: EcoLexicon:dust
xref: https://en.wikipedia.org/wiki/Dust
xref: SWEETRealm:Dust
is_a: ENVO:01000060 ! particulate environmental material
is_a: ENVO:01000814 ! solid environmental material
relationship: RO:0000086 PATO:0001824 ! has quality dry

[Term]
id: ENVO:00002010
name: saline water
def: "Water which contains a significant concentration of dissolved salts." []
comment: The threshold salt concentration for classifying water as saline varies, but typically begins at about 1,000 to 3,000 parts salt per million parts water or 0.1–0.3% salt by weight.
synonym: "salt water" EXACT []
xref: EcoLexicon:saltwater
xref: https://en.wikipedia.org/wiki/Saline_water
xref: SWEETRealm:SalineWater
xref: SWEETRealm:SaltWater
is_a: ENVO:00002006 ! liquid water
relationship: ENVO:02000200 CHEBI:26710 ! has increased levels of sodium chloride
relationship: RO:0000086 PATO:0001657 ! has quality increased osmolarity

[Term]
id: ENVO:00002011
name: fresh water
def: "Water which has a low concentration of dissolved solutes, particularly that of sodium chloride." []
comment: The lower bound of solute concentration required for water to be considered freshwater is variable, but is always less than that of seawater, and often cited as less than 1 gram of solutes per 1 litre of water.
synonym: "freshwater" EXACT []
xref: EcoLexicon:fresh_water
xref: https://en.wikipedia.org/wiki/Fresh_water
xref: LTER:216
xref: SWEETRealm:FreshWater
is_a: ENVO:00002006 ! liquid water

[Term]
id: ENVO:00002013
name: igneous rock
def: "Rock formed from molten magma." [https://en.wikipedia.org/wiki/Rock_%28geology%29]
xref: EcoLexicon:igneous_rock
xref: https://en.wikipedia.org/wiki/Igneous_rock
xref: SWEETRealm:IgneousRock
is_a: ENVO:00001995 ! rock
intersection_of: ENVO:00001995 ! rock
intersection_of: RO:0001000 ENVO:01000231 ! derives from lava
relationship: RO:0001000 ENVO:01000231 ! derives from lava

[Term]
id: ENVO:00002015
name: volcanic rock
def: "An igneous rock that results from magma reaching the surface either as lava or fragmental ejecta." [https://en.wikipedia.org/wiki/Rock_%28geology%29]
comment: Due to the general suggestion that volcanic rock simply comes from a volcanic process, it's not immediately clear whether this is interchangeable with igneous rock.
xref: EcoLexicon:volcanic_rock
xref: https://en.wikipedia.org/wiki/Volcanic_rock
xref: SWEETRealm:VolcanicRock
is_a: ENVO:00001995 ! rock
intersection_of: ENVO:00001995 ! rock
intersection_of: RO:0002354 ENVO:01000634 ! formed as result of volcanic eruption
relationship: RO:0002354 ENVO:01000634 ! formed as result of volcanic eruption

[Term]
id: ENVO:00002016
name: sedimentary rock
def: "A rock formed by deposition of either clastic sediments, organic matter, or chemical precipitates (evaporites), followed by compaction of the particulate matter and cementation during diagenesis." [https://en.wikipedia.org/wiki/Rock_%28geology%29]
xref: EcoLexicon:sedimentary_rock
xref: https://en.wikipedia.org/wiki/Sedimentary_rock
xref: SWEETRealm:SedimentaryRock
is_a: ENVO:00001995 ! rock

[Term]
id: ENVO:00002017
name: metamorphic rock
def: "A rock formed by subjecting any rock type (including previously-formed metamorphic rock) to different temperature and pressure conditions than those in which the original rock was formed. These temperatures and pressures are always higher than those at the Earth's surface and must be sufficiently high so as to change the original minerals into other mineral types or else into other forms of the same minerals (e.g. by recrystallisation)." [https://en.wikipedia.org/wiki/Rock_%28geology%29]
xref: EcoLexicon:metamorphic_rock
xref: https://en.wikipedia.org/wiki/Metamorphic_rock
xref: SWEETRealm:MetamorphicRock
is_a: ENVO:00001995 ! rock

[Term]
id: ENVO:00002018
name: sewage
def: "Wastewater that is contaminated with feces or urine," [https://en.wikipedia.org/wiki/Wastewater]
xref: https://en.wikipedia.org/wiki/Sewage
xref: SWEETRealm:Sewage
is_a: ENVO:00002001 ! waste water
intersection_of: ENVO:00002001 ! waste water
intersection_of: RO:0002473 ENVO:00002276 ! composed primarily of animal waste material
relationship: RO:0002473 ENVO:00002276 ! composed primarily of animal waste material

[Term]
id: ENVO:00002019
name: brackish water
def: "Water which has a higher salinity than fresh water but a lower salinity than marine water." []
xref: EcoLexicon:brackish_water
xref: https://en.wikipedia.org/wiki/Brackish_water
xref: LTER:702
xref: SPIRE:Brackish_water
xref: SWEETRealm:BrackishWater
is_a: ENVO:00002010 ! saline water

[Term]
id: ENVO:00002030
name: aquatic biome
def: "A biome which is determined by a water body and which has ecological climax communities adapted to life in or on water." []
xref: LTER:41
is_a: ENVO:00000428 ! biome
is_a: ENVO:01001787 ! aquatic ecosystem
intersection_of: ENVO:00000428 ! biome
intersection_of: RO:0002507 ENVO:00000063 ! determined by water body

[Term]
id: ENVO:00002040
name: wood
xref: EcoLexicon:wood
xref: https://en.wikipedia.org/wiki/Wood
xref: LTER:637
xref: SWEETRealm:Wood
is_a: ENVO:01000155 ! organic material
is_a: ENVO:01000814 ! solid environmental material

[Term]
id: ENVO:00002043
name: wastewater treatment plant
xref: EcoLexicon:wastewater_treatment_plant
xref: https://en.wikipedia.org/wiki/Wastewater_treatment_plant
is_a: ENVO:00002272 ! waste treatment plant

[Term]
id: ENVO:00002044
name: sludge
def: "The residual semi-solid material left from domestic or industrial processes, or wastewater treatment processes." [https://en.wikipedia.org/wiki/Sludge]
xref: EcoLexicon:sludge
xref: https://en.wikipedia.org/wiki/Sludge
is_a: ENVO:0010001 ! anthropogenic environmental material

[Term]
id: ENVO:00002045
name: anaerobic sediment
def: "Sediment characterised by the absence of oxygen." [ORCID:0000-0002-4366-3088]
synonym: "anoxic sediment" EXACT []
is_a: ENVO:00002007 ! sediment
intersection_of: ENVO:00002007 ! sediment
intersection_of: RO:0000086 PATO:0001456 ! has quality anaerobic
relationship: RO:0000086 PATO:0001456 ! has quality anaerobic

[Term]
id: ENVO:00002057
name: raw primary sludge
is_a: ENVO:00002044 ! sludge

[Term]
id: ENVO:00002058
name: secondary sludge
is_a: ENVO:00002044 ! sludge

[Term]
id: ENVO:00002059
name: biosolids
def: "A treated form of sludge, sometimes used as a fertilizer in agriculture." [https://en.wikipedia.org/wiki/Sludge]
xref: https://en.wikipedia.org/wiki/Biosolids
is_a: ENVO:00002044 ! sludge

[Term]
id: ENVO:00002060
name: oil sludge
def: "A solid or gel in motor oil caused by the oil gelling or solidifying, usually at temperatures lower than 100deg C." [https://en.wikipedia.org/wiki/Oil_sludge]
xref: https://en.wikipedia.org/wiki/Oil_sludge
is_a: ENVO:00002176 ! contaminated sludge

[Term]
id: ENVO:00002112
name: gold mine drainage
def: "Mine drainage which is formed as a result of the mining of gold." []
is_a: ENVO:00001996 ! mine drainage

[Term]
id: ENVO:00002114
name: chemically enriched sediment
def: "Sediment which has increased levels of one or more chemical compounds." []
is_a: ENVO:00002007 ! sediment
intersection_of: ENVO:00002007 ! sediment
intersection_of: ENVO:02000200 CHEBI:24431 ! has increased levels of chemical entity
relationship: ENVO:02000200 CHEBI:24431 ! has increased levels of chemical entity

[Term]
id: ENVO:00002115
name: petroleum enriched sediment
def: "Organically enriched sediment which has increased levels of petroleum." []
is_a: ENVO:00002202 ! organically enriched sediment
intersection_of: ENVO:00002202 ! organically enriched sediment
intersection_of: ENVO:02000200 ENVO:00002984 ! has increased levels of petroleum
relationship: ENVO:02000200 ENVO:00002984 ! has increased levels of petroleum

[Term]
id: ENVO:00002116
name: contaminated soil
def: "A portion of contaminated soil is a portion of soil with elevated levels of some contaminant." []
comment: "contaminant" is more of a disposition - any material entity can be a contaminant in particular circumstances.
is_a: ENVO:00003082 ! enriched soil

[Term]
id: ENVO:00002117
name: creosote contaminated soil
def: "Soil which has elevated concentrations of creosote." []
is_a: ENVO:00002116 ! contaminated soil
relationship: ENVO:02000200 ENVO:2000001 ! has increased levels of creosote

[Term]
id: ENVO:00002122
name: arsenic-rich mud
def: "Mud which has elevated concentrations of arsenic." []
is_a: ENVO:01000001 ! mud
intersection_of: ENVO:01000001 ! mud
intersection_of: ENVO:02000200 CHEBI:27563 ! has increased levels of arsenic atom
relationship: ENVO:02000200 CHEBI:27563 ! has increased levels of arsenic atom

[Term]
id: ENVO:00002127
name: stream sediment
comment: Revise adjacent to. Consider sampled stream sediment. Dry stream sediment.
is_a: ENVO:00002007 ! sediment
intersection_of: ENVO:00002007 ! sediment
intersection_of: RO:0002220 ENVO:00000023 ! adjacent to stream
relationship: RO:0002220 ENVO:00000023 ! adjacent to stream

[Term]
id: ENVO:00002129
name: anaerobic sludge
is_a: ENVO:00002044 ! sludge
intersection_of: ENVO:00002044 ! sludge
intersection_of: RO:0000086 PATO:0001456 ! has quality anaerobic
relationship: RO:0000086 PATO:0001456 ! has quality anaerobic

[Term]
id: ENVO:00002133
name: anaerobic mud
def: "Mud which has no or neglible concentrations of dissolved oxygen." []
synonym: "anoxic mud" EXACT []
is_a: ENVO:01000001 ! mud
intersection_of: ENVO:01000001 ! mud
intersection_of: RO:0000086 PATO:0001456 ! has quality anaerobic
relationship: RO:0000086 PATO:0001456 ! has quality anaerobic

[Term]
id: ENVO:00002134
name: anaerobic stream sediment
is_a: ENVO:00002045 ! anaerobic sediment
is_a: ENVO:00002127 ! stream sediment
intersection_of: ENVO:00002127 ! stream sediment
intersection_of: RO:0000086 PATO:0001456 ! has quality anaerobic

[Term]
id: ENVO:00002135
name: treated wood
xref: https://en.wikipedia.org/wiki/Treated_wood
is_a: ENVO:00002040 ! wood

[Term]
id: ENVO:00002136
name: arsenate treated wood
is_a: ENVO:00002135 ! treated wood
intersection_of: ENVO:00002040 ! wood
intersection_of: ENVO:02000200 CHEBI:29125 ! has increased levels of arsenate(3-)
relationship: ENVO:02000200 CHEBI:29125 ! has increased levels of arsenate(3-)

[Term]
id: ENVO:00002137
name: brackish estuary
def: "An estuary which is composed primarily of brackish water." []
is_a: ENVO:00000045 ! estuary

[Term]
id: ENVO:00002141
name: leachate
def: "The liquid produced when water percolates through any permeable material. It can contain either dissolved or suspended material, or usually both." [https://en.wikipedia.org/wiki/Leachate]
xref: https://en.wikipedia.org/wiki/Leachate
is_a: ENVO:00002006 ! liquid water

[Term]
id: ENVO:00002142
name: borax leachate
is_a: ENVO:00002141 ! leachate

[Term]
id: ENVO:00002145
name: chromate contaminated soil
def: "Soil which has elevated concentrations of chromate." []
is_a: ENVO:00003081 ! metal contaminated soil
relationship: ENVO:02000200 CHEBI:35404 ! has increased levels of chromate(2-)

[Term]
id: ENVO:00002146
name: xylene contaminated soil
def: "Soil which has elevated concentrations of xylene." []
is_a: ENVO:00002116 ! contaminated soil
relationship: ENVO:02000200 CHEBI:27338 ! has increased levels of xylene

[Term]
id: ENVO:00002149
name: sea water
def: "Water which has physicochemical properties that have been determined by the processes occuring in a sea or ocean." []
comment: This definition refers to water that is actually in a sea or ocean. This water may have a wide range of salinity levels.
synonym: "ocean water" EXACT []
synonym: "seawater" EXACT []
xref: EcoLexicon:sea_water
xref: https://en.wikipedia.org/wiki/Sea_water
xref: LTER:701
xref: SWEETRealm:SeaWater
is_a: ENVO:00002010 ! saline water

[Term]
id: ENVO:00002150
name: coastal sea water
def: "Coastal sea water is sea water that is adjacent to a coast." []
comment: The limits of what qualifies as "adjacent to" vary greatly. This should be defined on a data level and is left intentionally fuzzy here. The label is "coastal sea water" rather than "coastal water" as some large lakes are often said to have coasts.
synonym: "coastal ocean water" EXACT []
synonym: "coastal oceanic water" EXACT []
synonym: "coastal seawater" EXACT []
is_a: ENVO:00002149 ! sea water
intersection_of: ENVO:00002149 ! sea water
intersection_of: RO:0002220 ENVO:00000303 ! adjacent to sea coast
relationship: RO:0002220 ENVO:00000303 ! adjacent to sea coast

[Term]
id: ENVO:00002160
name: estuarine mud
def: "Mud which is part of an estuary." []
is_a: ENVO:01000001 ! mud
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:01000001 ! mud
intersection_of: BFO:0000050 ENVO:00000045 ! part of estuary
relationship: BFO:0000050 ENVO:00000045 ! part of estuary

[Term]
id: ENVO:00002167
name: platinum mine
is_a: ENVO:00000076 ! mine

[Term]
id: ENVO:00002168
name: gold mine
xref: https://en.wikipedia.org/wiki/Gold_mine
is_a: ENVO:00000076 ! mine

[Term]
id: ENVO:00002169
name: coal mine
xref: https://en.wikipedia.org/wiki/Coal_mine
is_a: ENVO:00000076 ! mine

[Term]
id: ENVO:00002173
name: hospital
def: "A hospital is a building in which health care services are  provided by specialized staff and equipment." [https://en.wikipedia.org/wiki/Hospital]
xref: https://en.wikipedia.org/wiki/Hospital
is_a: ENVO:03501134 ! healthcare facility

[Term]
id: ENVO:00002176
name: contaminated sludge
is_a: ENVO:00002044 ! sludge

[Term]
id: ENVO:00002177
name: 1,4-dioxane contaminated sludge
is_a: ENVO:00002176 ! contaminated sludge
intersection_of: ENVO:00002044 ! sludge
intersection_of: ENVO:02000200 CHEBI:47032 ! has increased levels of 1,4-dioxane
relationship: ENVO:02000200 CHEBI:47032 ! has increased levels of 1,4-dioxane

[Term]
id: ENVO:00002180
name: naphthalene enriched sediment
def: "Organically enriched sediment which has increased levels of naphthalene." []
is_a: ENVO:00002202 ! organically enriched sediment
is_a: ENVO:03600001 ! chemically contaminated sediment
intersection_of: ENVO:00002202 ! organically enriched sediment
intersection_of: ENVO:02000200 CHEBI:16482 ! has increased levels of naphthalene
relationship: ENVO:02000200 CHEBI:16482 ! has increased levels of naphthalene

[Term]
id: ENVO:00002182
name: nitrobenzene enriched sediment
def: "Organically enriched sediment which has increased levels of nitrobenzene." []
is_a: ENVO:00002202 ! organically enriched sediment
intersection_of: ENVO:00002202 ! organically enriched sediment
intersection_of: ENVO:02000200 CHEBI:27798 ! has increased levels of nitrobenzene
relationship: ENVO:02000200 CHEBI:27798 ! has increased levels of nitrobenzene

[Term]
id: ENVO:00002186
name: contaminated water
synonym: "polluted water" EXACT []
xref: EcoLexicon:water_pollution
xref: https://en.wikipedia.org/wiki/Contaminated_water
is_a: ENVO:00002006 ! liquid water

[Term]
id: ENVO:00002193
name: pulp-bleaching waste water
is_a: ENVO:00002001 ! waste water

[Term]
id: ENVO:00002202
name: organically enriched sediment
def: "Chemically-enriched sediment which has increased levels of organic compounds." []
is_a: ENVO:00002114 ! chemically enriched sediment
intersection_of: ENVO:00002114 ! chemically enriched sediment
intersection_of: ENVO:02000200 CHEBI:50860 ! has increased levels of organic molecular entity
relationship: ENVO:02000200 CHEBI:50860 ! has increased levels of organic molecular entity

[Term]
id: ENVO:00002203
name: inorganically enriched sediment
def: "Chemically-enriched sediment which has increased levels of inorganic compounds." []
is_a: ENVO:00002114 ! chemically enriched sediment
intersection_of: ENVO:00002114 ! chemically enriched sediment
intersection_of: ENVO:02000200 CHEBI:24835 ! has increased levels of inorganic molecular entity
relationship: ENVO:02000200 CHEBI:24835 ! has increased levels of inorganic molecular entity

[Term]
id: ENVO:00002206
name: coal mine waste material
is_a: ENVO:00002267 ! industrial waste material
is_a: ENVO:01000813 ! astronomical body part
relationship: BFO:0000050 ENVO:00002169 ! part of coal mine

[Term]
id: ENVO:00002207
name: self-heating coal mine waste material
is_a: ENVO:00002206 ! coal mine waste material

[Term]
id: ENVO:00002214
name: power plant
def: "A power plant is a building which contains one or more generators which convert mechanical energy into electrical energy through the relative motion between a magnetic field and a conductor. The energy source harnessed to turn the generator varies widely." [https://en.wikipedia.org/wiki/Power_station]
synonym: "generating plant" EXACT []
synonym: "generating station" EXACT []
synonym: "power station" EXACT []
synonym: "powerhouse" EXACT []
xref: https://en.wikipedia.org/wiki/Power_plant
xref: SWEETRealm:PowerPlant
is_a: ENVO:00003861 ! industrial building
relationship: ENVO:2000036 ENVO:2000015 ! generates energy

[Term]
id: ENVO:00002215
name: geothermal power plant
def: "A geothermal power plant is a power plant which uses heat generated by the decay of radioactive isotopes in the Earth's mantle and crust as well as primordial heat left over from the formation of the Earth to drive its generators." [https://en.wikipedia.org/wiki/Earth's_internal_heat_budget, https://en.wikipedia.org/wiki/Geothermal_energy]
xref: https://en.wikipedia.org/wiki/Geothermal_power_plant
xref: SWEETRealm:GeothermalPowerPlant
is_a: ENVO:00002214 ! power plant

[Term]
id: ENVO:00002221
name: shop
def: "A building in which a business presents a selection of goods and offers to trade or sell them to customers for money or other goods." [https://en.wikipedia.org/wiki/Shopping]
synonym: "retail shop" EXACT []
synonym: "retail store" EXACT []
synonym: "retailer" EXACT []
xref: https://en.wikipedia.org/wiki/Shopping
is_a: ENVO:01001222 ! commercial building

[Term]
id: ENVO:00002228
name: pond water
is_a: ENVO:00002011 ! fresh water
is_a: ENVO:01000813 ! astronomical body part
relationship: BFO:0000050 ENVO:00000033 ! part of pond

[Term]
id: ENVO:00002259
name: agricultural soil
def: "Soil which is part of an ecosystem used for agricultural activities." []
is_a: ENVO:00001998 ! soil
relationship: BFO:0000050 ENVO:00000077 ! part of agricultural ecosystem

[Term]
id: ENVO:00002261
name: forest soil
def: "A portion of soil which is found in a forested area." []
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0001025 ENVO:00000111 ! located in forested area
relationship: RO:0001025 ENVO:00000111 ! located in forested area

[Term]
id: ENVO:00002262
name: clay soil
def: "Soil which is primarily composed of clay." []
is_a: ENVO:00001998 ! soil
relationship: RO:0002473 ENVO:00002982 ! composed primarily of clay

[Term]
id: ENVO:00002263
name: garden soil
def: "A portion of soil which is found in a garden." []
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0001025 ENVO:00000011 ! located in garden
relationship: BFO:0000050 ENVO:00000011 ! part of garden
relationship: RO:0001025 ENVO:00000011 ! located in garden

[Term]
id: ENVO:00002264
name: waste material
def: "A material which is not the desired output of a process and which is typically the input of a process which removes it from its producer (e.g. a disposal process)." []
xref: EcoLexicon:waste
xref: https://en.wikipedia.org/wiki/Waste
xref: SWEETRealm:Waste
is_a: ENVO:00010483 ! environmental material
intersection_of: ENVO:00010483 ! environmental material
intersection_of: RO:0000087 ENVO:01000665 ! has role waste role
relationship: RO:0000087 ENVO:01000665 ! has role waste role

[Term]
id: ENVO:00002266
name: chicken breeding waste material
is_a: ENVO:01000371 ! agricultural waste material

[Term]
id: ENVO:00002267
name: industrial waste material
def: "Industrial wastes are liquid, solid and gaseous wastes originating from the manufacture of specific products." [http://stats.oecd.org/glossary/detail.asp?ID=1340, ISBN:978-92-1-161386-5]
is_a: ENVO:00002264 ! waste material

[Term]
id: ENVO:00002271
name: nuclear power plant
def: "A nuclear power plant is a power plant which uses heat generated by a radioactive decay in a nuclear reactor to convert water into steam in order to drive turbines in electrical generators through pressure." [https://en.wikipedia.org/wiki/Nuclear_power_plant]
xref: https://en.wikipedia.org/wiki/Nuclear_power_plant
is_a: ENVO:00002214 ! power plant
relationship: BFO:0000051 ENVO:02000137 ! has part nuclear power reactor

[Term]
id: ENVO:00002272
name: waste treatment plant
synonym: "WWTP" EXACT []
is_a: ENVO:00003861 ! industrial building

[Term]
id: ENVO:00002273
name: fluvisol
def: "Fluvisols accommodate genetically young, azonal soils in alluvial deposits." [FAO:http\://fao.org/ag/agl/agll/wrb/doc/wrb2006final.pdf]
xref: https://en.wikipedia.org/wiki/Fluvisols
is_a: ENVO:00001998 ! soil

[Term]
id: ENVO:00002274
name: stagnosol
def: "Stagnosols are soils with a perched water table showing redoximorphic features caused by surface water. Stagnosols are periodically wet and mottled in the topsoil and subsoil, with or without concretions and/or bleaching." [FAO:http\://fao.org/ag/agl/agll/wrb/doc/wrb2006final.pdf]
is_a: ENVO:00001998 ! soil

[Term]
id: ENVO:00002275
name: technosol
def: "Technosols are soils whose properties and pedogenesis are dominated by their technical origin. They contain a significant amount of artefacts (something in the soil recognizably made or extracted from the earth by humans), or are sealed by technic hard rock (material created by humans, having properties unlike natural rock). They include soils from wastes (landfills, sludge, cinders, mine spoils and ashes), pavements with their underlying unconsolidated materials, soils with geomembranes and constructed soils in human-made materials." [FAO:http\://fao.org/ag/agl/agll/wrb/doc/wrb2006final.pdf]
is_a: ENVO:00001998 ! soil
relationship: BFO:0000050 ENVO:01000983 ! part of technosphere

[Term]
id: ENVO:00002276
name: animal waste material
xref: https://en.wikipedia.org/wiki/Animal_waste
xref: SWEETRealm:AnimalWaste
is_a: ENVO:00002873 ! organic waste material

[Term]
id: ENVO:00002869
name: hay
def: "Hay is grass, legumes or other herbaceous plants that have been cut, dried, and stored for use as animal fodder, particularly for grazing livestock such as cattle, horses, goats, and sheep." [https://en.wikipedia.org/wiki/Hay]
xref: https://en.wikipedia.org/wiki/Hay
is_a: ENVO:0010003 ! agricultural environmental material

[Term]
id: ENVO:00002870
name: adobe
def: "A natural building material mode from sand, clay, water, and some kind of fibrous or organic material (sticks, straw, and/or manure)." [https://en.wikipedia.org/wiki/Adobe]
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:01000814 ! solid environmental material
relationship: BFO:0000051 ENVO:00002982 ! has part clay
relationship: BFO:0000051 ENVO:01000017 ! has part sand

[Term]
id: ENVO:00002872
name: bagasse
def: "The biomass remaining after sugarcane stalks are crushed to extract their juice." [https://en.wikipedia.org/wiki/Bagasse]
synonym: "sugarcane bagasse" EXACT []
xref: https://en.wikipedia.org/wiki/Bagasse
is_a: ENVO:00002264 ! waste material

[Term]
id: ENVO:00002873
name: organic waste material
xref: https://en.wikipedia.org/wiki/Organic_waste
is_a: ENVO:01000373 ! biological waste material

[Term]
id: ENVO:00002874
name: air conditioning unit
def: "A manufactuered product which is capable of removing heat and controlling the humidity of the air within a site." [] {def="Air:conditioning"}
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:00002875
name: oil contaminated soil
def: "Soil which has elevated concentrations of oil." []
is_a: ENVO:00002116 ! contaminated soil
relationship: ENVO:02000200 ENVO:00002985 ! has increased levels of oil

[Term]
id: ENVO:00002982
name: clay
def: "Particulate environmental material which 1) is composed primarily of clay particles, with only minor proportions of other materials, 2) demonstrates plasticity when wet, and 3) is capable of hardening when dried or fired." [https://en.wikipedia.org/wiki/Clay]
comment: This definition is intentionally ambiguous to support the multiple thresholds set by different authorities.The distinction between silt and clay varies by discipline. Geologists and soil scientists usually consider the separation to occur at a particle size of 2 μm (clays being finer than silts), sedimentologists often use 4–5 μm, and colloid chemists use 1 μm. Geotechnical engineers distinguish between silts and clays based on the plasticity properties of the soil, as measured by the soils' Atterberg limits. ISO 14688 grades clay particles as being smaller than 2 μm and silt particles as being larger. Mixtures of sand, silt and less than 40% clay are called loam. Similar mixtures with greater than 40% clay are often considered clay soils. {xref="https://en.wikipedia.org/wiki/Clay"}
xref: EcoLexicon:clay
xref: SWEETRealm:Clay
is_a: ENVO:01000060 ! particulate environmental material
disjoint_from: ENVO:01000016 ! silt
relationship: BFO:0000051 ENVO:01003003 ! has part particle of clay
relationship: RO:0000086 PATO:0000984 ! has quality porous

[Term]
id: ENVO:00002983
name: fuel oil
def: "An oil which 1) is liquid at room temperature (approximately 20 degrees Celsius) 2) is intended to be burned in a furnace or boiler for the generation of heat or used in an engine for the generation of power, 3) is obtained from petroleum distillation, either as a distillate or a residue, 4) composed of long hydrocarbon chains, particularly alkanes, cycloalkanes and aromatics." [https://en.wikipedia.org/wiki/Fuel_oil]
comment: Oils having a flash point of approximately 42 degrees Celsius and oils burned in cotton or wool-wick burners are not typically considered fuel oils. The term fuel oil is also used in a stricter sense to refer only to the heaviest commercial fuel that can be obtained from crude oil, i.e., heavier than gasoline and naphtha. {xref="https://en.wikipedia.org/wiki/Fuel_oil"}
synonym: "furnace oil" EXACT []
synonym: "heavy oil" EXACT []
synonym: "marine fuel" EXACT []
is_a: ENVO:00002985 ! oil
relationship: RO:0000087 CHEBI:35230 ! has role fossil fuel

[Term]
id: ENVO:00002984
name: petroleum
def: "A naturally occurring flammable liquid consisting of a complex mixture of hydrocarbons of various molecular weights and other liquid organic compounds, that are found in geologic formations beneath the planetary surfaces." [https://en.wikipedia.org/wiki/Petroleum]
xref: https://en.wikipedia.org/wiki/Petroleum
is_a: ENVO:00002985 ! oil
relationship: RO:0000087 CHEBI:35230 ! has role fossil fuel

[Term]
id: ENVO:00002985
name: oil
def: "A nonpolar, hydrophobic, and lipophilic material which is a viscous liquid at ambient temperatures (about 20 degrees Celsius) or slightly warmer." [https://en.wikipedia.org/wiki/Oil]
xref: EcoLexicon:oil
is_a: ENVO:01000815 ! liquid environmental material
is_a: ENVO:2000045 ! hydrocarbon-based environmental material
relationship: RO:0000086 PATO:0001885 ! has quality hydrophobic

[Term]
id: ENVO:00003030
name: silage
def: "A fermented, high-moisture forage that can be fed to ruminants." [https://en.wikipedia.org/wiki/Silage]
xref: https://en.wikipedia.org/wiki/Silage
is_a: ENVO:0010003 ! agricultural environmental material

[Term]
id: ENVO:00003031
name: animal manure
def: "Manure which is derived from the waste products of animals." []
comment: This is interesting in that the "role" aspect of "waste" is (or can be) replaced by another role "fertilizer". Thus, the positioning of "manure" under waste may not be totally correct.
is_a: ENVO:03501300 ! manure

[Term]
id: ENVO:00003032
name: fresh animal manure
is_a: ENVO:00003031 ! animal manure

[Term]
id: ENVO:00003064
name: drinking water
def: "Drinking water is water which may be consumed by humans with no adverse effects on their health." []
synonym: "potable water" EXACT []
xref: EcoLexicon:drinking_water
xref: https://en.wikipedia.org/wiki/Drinking_water
xref: SWEETRealm:DrinkingWater
is_a: ENVO:00002011 ! fresh water

[Term]
id: ENVO:00003065
name: distilled water
xref: https://en.wikipedia.org/wiki/Distilled_water
is_a: ENVO:00002006 ! liquid water

[Term]
id: ENVO:00003074
name: manufactured product
def: "A material entity that has been processed by humans or their technology in any way, including intermediate products as well as final products." [] {comment="https://en.wikipedia.org/wiki/Manufactured_product"}
synonym: "manufactured good" EXACT []
is_a: BFO:0000040 ! material entity
intersection_of: BFO:0000040 ! material entity
intersection_of: RO:0002353 ENVO:01000993 ! output of manufacturing process
relationship: RO:0002353 ENVO:01000993 ! output of manufacturing process

[Term]
id: ENVO:00003076
name: glue
def: "A function realised by an environmental material when used to bind material entities together." [https://en.wikipedia.org/wiki/Glue]
synonym: "adhesive" EXACT []
synonym: "mucilage" EXACT []
xref: https://en.wikipedia.org/wiki/Glue
is_a: BFO:0000034 ! function

[Term]
id: ENVO:00003081
name: metal contaminated soil
def: "Soil which has elevated concentrations of metals." []
is_a: ENVO:00002116 ! contaminated soil
relationship: ENVO:02000200 CHEBI:33521 ! has increased levels of metal atom

[Term]
id: ENVO:00003082
name: enriched soil
def: "A portion of enriched soil is a portion of soil with elevated levels of some material entity." []
comment: This could be demoted to an inferred class if issues with double inheritance arise.
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: ENVO:02000200 BFO:0000040 ! has increased levels of material entity
relationship: ENVO:02000200 BFO:0000040 ! has increased levels of material entity

[Term]
id: ENVO:00003083
name: sarcosine enriched soil
def: "A portion of sarcosine enriched soil is a portion of soil with elevated levels of sarcosine." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:15611 ! has increased levels of sarcosine
relationship: ENVO:02000200 CHEBI:15611 ! has increased levels of sarcosine

[Term]
id: ENVO:00003084
name: trimethylamine enriched soil
def: "A portion of trimethylamine enriched soil is a portion of soil with elevated levels of trimethylamine." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:18139 ! has increased levels of trimethylamine
relationship: ENVO:02000200 CHEBI:18139 ! has increased levels of trimethylamine

[Term]
id: ENVO:00003087
name: acetamide enriched soil
def: "A portion of acetamide enriched soil is a portion of soil with elevated levels of acetamide." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:27856 ! has increased levels of acetamide
relationship: ENVO:02000200 CHEBI:27856 ! has increased levels of acetamide

[Term]
id: ENVO:00003088
name: pantothenate enriched soil
def: "A portion of pantothenate enriched soil is a portion of soil with elevated levels of pantothenate." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:16454 ! has increased levels of pantothenate
relationship: ENVO:02000200 CHEBI:16454 ! has increased levels of pantothenate

[Term]
id: ENVO:00003089
name: testosterone enriched soil
def: "A portion of testosterone enriched soil is a portion of soil with elevated levels of testosterone." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:17347 ! has increased levels of testosterone
relationship: ENVO:02000200 CHEBI:17347 ! has increased levels of testosterone

[Term]
id: ENVO:00003091
name: threonine enriched soil
def: "A portion of threonine enriched soil is a portion of soil with elevated levels of threonine." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:26986 ! has increased levels of threonine
relationship: ENVO:02000200 CHEBI:26986 ! has increased levels of threonine

[Term]
id: ENVO:00003092
name: salicylate enriched soil
def: "A portion of salicylate enriched soil is a portion of soil with elevated levels of salicylate." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:30762 ! has increased levels of salicylate
relationship: ENVO:02000200 CHEBI:30762 ! has increased levels of salicylate

[Term]
id: ENVO:00003095
name: quinate enriched soil
def: "A portion of quinate enriched soil is a portion of soil with elevated levels of quinate." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:26490 ! has increased levels of quinate
relationship: ENVO:02000200 CHEBI:26490 ! has increased levels of quinate

[Term]
id: ENVO:00003096
name: tap water
xref: https://en.wikipedia.org/wiki/Tap_water
is_a: ENVO:00002011 ! fresh water

[Term]
id: ENVO:00003861
name: industrial building
def: "An industrial building is a building within which goods are produced and, optionally, stored or within which services are rendered." [https://en.wikipedia.org/wiki/Industry]
comment: It's possible that this will become an inferred class in the future. The United Nations' International Standard Industrial Classification should be referred to when expanding this branch. ISIC can also be used to identify processes. See http://unstats.un.org/unsd/cr/registry/regcst.asp?Cl=27&Lg=1.
is_a: ENVO:00000073 ! building
intersection_of: ENVO:00000073 ! building
intersection_of: RO:0000056 ENVO:01001450 ! participates in usage of an environment for industry
relationship: RO:0000056 ENVO:01001450 ! participates in usage of an environment for industry

[Term]
id: ENVO:00005748
name: dry soil
def: "Soil which has little to no water content and in which minerals and other soluble chemical entities have either bonded or become adsorbed to sold particles due to insufficient water availability." []
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0000086 PATO:0001824 ! has quality dry
relationship: RO:0000086 PATO:0001824 ! has quality dry

[Term]
id: ENVO:00005749
name: farm soil
def: "A portion of soil which is part of a cropland or a rangeland biome." []
is_a: ENVO:00001998 ! soil

[Term]
id: ENVO:00005750
name: grassland soil
def: "A portion of soil which is found in a grassland." []
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0001025 ENVO:00000106 ! located in grassland area
relationship: RO:0001025 ENVO:00000106 ! located in grassland area

[Term]
id: ENVO:00005753
name: urea enriched soil
def: "A portion of urea enriched soil is a portion of soil with elevated levels of urea." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:16199 ! has increased levels of urea
relationship: ENVO:02000200 CHEBI:16199 ! has increased levels of urea

[Term]
id: ENVO:00005755
name: field soil
def: "Soil which is part of an agricultural field." []
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: BFO:0000050 ENVO:00000114 ! part of agricultural field
relationship: BFO:0000050 ENVO:00000114 ! part of agricultural field

[Term]
id: ENVO:00005762
name: chloropicrin enriched soil
def: "A portion of chloropicrin enriched soil is a portion of soil with elevated levels of chloropicrin." []
is_a: ENVO:00003082 ! enriched soil
intersection_of: ENVO:00003082 ! enriched soil
intersection_of: ENVO:02000200 CHEBI:39285 ! has increased levels of chloropicrin
relationship: ENVO:02000200 CHEBI:39285 ! has increased levels of chloropicrin

[Term]
id: ENVO:00005767
name: manured soil
def: "Soil which has, as a part, a portion of either fresh or processed animal manure." []
is_a: ENVO:00001998 ! soil

[Term]
id: ENVO:00005771
name: muddy soil
def: "Soil which is composed of a large proportion of mud, thus having properties resembling mud." []
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0002473 ENVO:01000001 ! composed primarily of mud
relationship: RO:0002473 ENVO:01000001 ! composed primarily of mud

[Term]
id: ENVO:00005786
name: upland soil
def: "Soil which is part of some elevated land." [https://www.merriam-webster.com/dictionary/upland]
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: BFO:0000050 ENVO:00000176 ! part of elevated landform
relationship: BFO:0000050 ENVO:00000176 ! part of elevated landform

[Term]
id: ENVO:00005792
name: underground water
def: "Water which has physicochemical properties determined by processes which occur beneath the planetary crust." []
comment: This class references any water that's under a planetary surface. For water that is in an aquifer, see "groundwater" (ENVO:01001004). Previously, this class included both.
xref: SWEETRealm:UndergroundWater
is_a: ENVO:00002006 ! liquid water
relationship: RO:0001025 ENVO:01000941 ! located in planetary subsurface zone

[Term]
id: ENVO:00005795
name: marine mud
def: "Mud which is part of a marine ecosystem." []
is_a: ENVO:01000001 ! mud
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:01000001 ! mud
intersection_of: BFO:0000050 ENVO:00000447 ! part of marine biome
relationship: BFO:0000050 ENVO:00000447 ! part of marine biome

[Term]
id: ENVO:00005800
name: desert sand
def: "Sand which is part of a desert." []
is_a: ENVO:01000017 ! sand
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:01000017 ! sand
intersection_of: BFO:0000050 ENVO:01001357 ! part of desert
relationship: BFO:0000050 ENVO:01001357 ! part of desert

[Term]
id: ENVO:00010483
name: environmental material
def: "A material entity which other material entities in an environmental system are primarily or partially composed of." [http://ontology.buffalo.edu/smith/articles/niches.html, https://dx.doi.org/10.1186/2041-1480-4-43, https://en.wikipedia.org/wiki/Material]
comment: Everything under this parent must be a mass noun (i.e. not countable). All subclasses are to be understood as being composed primarily of the named entity, rather than restricted to that entity. For example, "ENVO:water" is to be understood as "environmental material composed primarly of some CHEBI:water".
synonym: "portion of environmental material" EXACT []
is_a: BFO:0000040 ! material entity
relationship: RO:0002473 CHEBI:33839 ! composed primarily of macromolecule

[Term]
id: ENVO:00010504
name: surface layer
def: "A layer of some material entity which is adjacent to one or more of its external boundaries and directly interacts with its immediate surroundings." [URL:http\://www.merriam-webster.com/dictionary/surface]
comment: This class is distinct from a geometric surface, which is two-dimensional. The idea of "uppermost" may be problematic. Further, the definition of layer (the superclass of surface in rev 133) references surface. This may be another issue. Perhaps this can be made into an inferred class using 'bounding layer of' some material entity, note that 'bounding layer' implies containment, which may not be valid here.
xref: EcoLexicon:surface
xref: http://sweetontology.net/reprSpaceGeometry/Surface
xref: https://en.wikipedia.org/wiki/Surface
is_a: ENVO:01001684 ! interface layer

[Term]
id: ENVO:00010505
name: aerosol
def: "Airborne solid particles (also called dust or particulate matter (PM)) or liquid droplets." [https://en.wikipedia.org/wiki/Aerosol]
comment: Should connect to PATO as "quality of an aerosol"
xref: EcoLexicon:aerosol
xref: SWEETRealm:Aerosol
is_a: ENVO:00010483 ! environmental material
relationship: BFO:0000051 ENVO:01000797 ! has part gaseous environmental material
relationship: RO:0000086 PATO:0001332 ! has quality amorphous

[Term]
id: ENVO:00010625
name: zoological garden
def: "A facility in which animals are confined within enclosures and displayed to the public, and in which they may also be bred." [https://en.wikipedia.org/wiki/Zoo]
synonym: "zoo" EXACT []
synonym: "zoological park" EXACT []
is_a: ENVO:00000011 ! garden

[Term]
id: ENVO:00012408
name: aquifer
def: "An underground layer of water-bearing permeable rock or unconsolidated materials (gravel, sand, silt, or clay) from which groundwater can be usefully extracted using a water well." [https://en.wikipedia.org/wiki/Aquifer]
xref: EcoLexicon:aquifer
xref: https://en.wikipedia.org/wiki/Aquifer
xref: SWEETRealm:Aquifer
is_a: ENVO:01001275 ! solid layer
relationship: BFO:0000051 ENVO:00000328 ! has part vadose zone
relationship: BFO:0000051 ENVO:00000329 ! has part phreatic zone

[Term]
id: ENVO:0010001
name: anthropogenic environmental material
def: "Anthropogenic material in or on which organisms may live." [MA:ma]
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:0010003
name: agricultural environmental material
is_a: ENVO:0010001 ! anthropogenic environmental material

[Term]
id: ENVO:01000001
name: mud
def: "An environmental material which is a liquid or semi-liquid mixture of water and some combination of soil, silt, and clay particles." [https://en.wikipedia.org/wiki/Mud]
xref: EcoLexicon:mud
xref: https://en.wikipedia.org/wiki/Mud
xref: LTER:356
xref: SWEETRealm:Mud
is_a: ENVO:00010483 ! environmental material
relationship: BFO:0000051 ENVO:00001998 ! has part soil
relationship: BFO:0000051 ENVO:00002006 ! has part liquid water

[Term]
id: ENVO:01000016
name: silt
def: "Particulate environmental material which is primarily composed of silt particles." [https://en.wikipedia.org/wiki/Silt]
comment: This definition is intentionally ambiguous to support the multiple thresholds set by different authorities. Some authorities consider this soil material that contains 80% or more silt and less than 12% clay. In the Udden-Wentworth scale (due to Krumbein), silt particles range between 0.0039 to 0.0625 mm, larger than clay but smaller than sand particles. ISO 14688 grades silts between 0.002 mm and 0.063 mm. In actuality, silt is chemically distinct from clay, and unlike clay, grains of silt are approximately the same size in all dimensions; furthermore, their size ranges overlap. Clays are formed from thin plate-shaped particles held together by electrostatic forces, so present a cohesion. According to the U.S. Department of Agriculture Soil Texture Classification system, the sand-silt distinction is made at the 0.05 mm particle size. The USDA system has been adopted by the Food and Agriculture Organization (FAO). In the Unified Soil Classification System (USCS) and the AASHTO Soil Classification system, the sand-silt distinction is made at the 0.075 mm particle size (i.e., material passing the #200 sieve). Silts and clays are distinguished mechanically by their plasticity. {xref="https://en.wikipedia.org/wiki/Silt", xref="https://sis.agr.gc.ca/cansis/glossary/t/index.html"}
xref: EcoLexicon:silt
xref: https://en.wikipedia.org/wiki/Silt
xref: SWEETRealm:Silt
is_a: ENVO:01000060 ! particulate environmental material
disjoint_from: ENVO:01000017 ! sand
relationship: BFO:0000051 ENVO:00000343 ! has part particle of silt
relationship: RO:0000053 PATO:0000150 ! has characteristic texture
relationship: RO:0000086 PATO:0000984 ! has quality porous

[Term]
id: ENVO:01000017
name: sand
def: "Particulate environmental material which is composed primarily of particles of sand with only minor proportions of other substances." [https://en.wikipedia.org/wiki/Sand]
comment: This definition is intentionally ambiguous to support the multiple thresholds set by different authorities. Some authorities consider as sands soil material that contains 85% or more sand; the percentage of silt plus 1.5 times the percentage of clay does not exceed 15. coarse sand (sable grossier) 25% or more very coarse and coarse sand, and less than 50% any other one grade of sand. {xref="https://sis.agr.gc.ca/cansis/glossary/t/index.html"}
xref: EcoLexicon:sand
xref: https://en.wikipedia.org/wiki/Sand
xref: LTER:484
xref: SWEETRealm:Sand
is_a: ENVO:01000060 ! particulate environmental material
relationship: BFO:0000051 ENVO:00000340 ! has part particle of sand
relationship: RO:0000053 PATO:0000150 ! has characteristic texture
relationship: RO:0000053 PATO:0000984 ! has characteristic porous

[Term]
id: ENVO:01000018
name: gravel
def: "An environmental material which is composed primarily of pieces of gravel." [https://en.wikipedia.org/wiki/Gravel]
comment: As with all size-based classifications, there is considerable variation in what is considered gravel.
xref: EcoLexicon:gravel
xref: SWEETRealm:Gravel
is_a: ENVO:01000814 ! solid environmental material
relationship: BFO:0000051 ENVO:00000341 ! has part piece of gravel
relationship: RO:0000086 PATO:0000984 ! has quality porous
relationship: RO:0000086 PATO:0001759 ! has quality granular

[Term]
id: ENVO:01000048
name: ocean biome
def: "A marine biome which is determined by an ocean." [https://en.wikipedia.org/wiki/Ocean, ORCID:0000-0002-4366-3088]
comment: Ocean biomes are determined by major bodies of saline water, principal components of the hydrosphere. Approximately 71% of the Earth's surface is covered by ocean, a continuous body of water that is customarily divided into several principal oceans and smaller seas. More than half of this area is over 3,000 metres (9,800 ft) deep. Average oceanic salinity is around 35 parts per thousand (ppt) (3.5%), and nearly all seawater has a salinity in the range of 30 to 38 ppt.
is_a: ENVO:00000447 ! marine biome
intersection_of: ENVO:00000428 ! biome
intersection_of: RO:0002507 ENVO:00000015 ! determined by ocean
relationship: RO:0002507 ENVO:00000015 ! determined by ocean

[Term]
id: ENVO:01000057
name: marine algal bloom
def: "A marine algal bloom is a rapid increase or accumulation in the population of algae in a marine system. Typically, only one or a small number of phytoplankton  species are involved. Although there is no officially recognized threshold level, algae can be considered to be blooming at concentrations of hundreds to thousands of cells per milliliter, depending on the severity." [https://en.wikipedia.org/wiki/Algal_bloom, ORCID:0000-0002-4366-3088]
xref: EcoLexicon:red_tide
is_a: ENVO:2000004 ! algal bloom
intersection_of: ENVO:2000004 ! algal bloom
intersection_of: RO:0001025 ENVO:00000447 ! located in marine biome
relationship: RO:0001025 ENVO:00000447 ! located in marine biome

[Term]
id: ENVO:01000060
name: particulate environmental material
def: "An environmental material which is composed primarily of particles." []
is_a: ENVO:00010483 ! environmental material
relationship: BFO:0000051 ENVO:01003002 ! has part particle
relationship: RO:0000086 PATO:0001759 ! has quality granular

[Term]
id: ENVO:01000155
name: organic material
def: "Environmental material derived from living organisms and composed primarily of one or more biomacromolecules." [ISBN:978-0-618-45504-1, ORCID:0000-0002-4366-3088]
synonym: "biomass" EXACT []
xref: EcoLexicon:organic_material
is_a: ENVO:00010483 ! environmental material
intersection_of: ENVO:00010483 ! environmental material
intersection_of: RO:0002473 CHEBI:33694 ! composed primarily of biomacromolecule
relationship: RO:0002473 CHEBI:33694 ! composed primarily of biomacromolecule

[Term]
id: ENVO:01000174
name: forest biome
def: "A forest ecosystem which is undergoing climactic ecological succession." []
xref: LTER:212
xref: SPIRE:Forest
is_a: ENVO:00000446 ! terrestrial biome
is_a: ENVO:01001243 ! forest ecosystem
intersection_of: ENVO:01001243 ! forest ecosystem
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:01000177
name: grassland biome
def: "A grassland ecosystem in which dominant ecological communities have reached their climax successional state." []
xref: SPIRE:Savannah_or_grassland
is_a: ENVO:00000446 ! terrestrial biome
is_a: ENVO:01001206 ! grassland ecosystem
intersection_of: ENVO:01001206 ! grassland ecosystem
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:01000179
name: desert biome
def: "A desert ecosystem which is undergoing climactic ecological succession." []
xref: SPIRE:Desert_or_dune
is_a: ENVO:00000428 ! biome
is_a: ENVO:01001780 ! desert ecosystem
intersection_of: ENVO:01001780 ! desert ecosystem
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession
relationship: RO:0002131 ENVO:00000097 ! overlaps desert area

[Term]
id: ENVO:01000203
name: environmental condition
def: "An environmental condition is a range of a determinate quality or combination of qualities that are present in an environmental system." [DOI:10.1186/2041-1480-4-43]
comment: A condition defines a restricted range of a given quality or combination of qualities. If an environment class, E, has_condition C, then all qualities listed in C are restricted to the ranges defined in C in E. This is not intended as a logical conditional.
is_a: PATO:0001018 ! physical quality

[Term]
id: ENVO:01000219
name: anthropogenic terrestrial biome
def: "An anthropogenic terrestrial biome is a terrestrial biome which has community structures determined by human activity." [http://www.eoearth.org/view/article/150128/]
comment: Preliminary definition.
synonym: "anthrome" EXACT []
synonym: "human biome" EXACT []
is_a: ENVO:00000446 ! terrestrial biome
is_a: ENVO:01001828 ! anthropised ecosystem
intersection_of: ENVO:00000446 ! terrestrial biome
intersection_of: RO:0002354 ENVO:01000952 ! formed as result of anthropisation

[Term]
id: ENVO:01000230
name: arid
def: "An environmental condition in which annual precipitation is less than half of annual potential evapotranspiration." []
xref: EcoLexicon:aridity
is_a: ENVO:01000203 ! environmental condition

[Term]
id: ENVO:01000231
name: lava
def: "Lava is a mixture of molten or semi-molten rock, volatiles, and solids which has extruded beyond a planetary crust." [https://en.wikipedia.org/wiki/Lava]
comment: Some use 'lava' to refer to rock that is formed when lava cools. This is not the intended meaning of this class. See 'igneous rock' or similar.
xref: EcoLexicon:lava
xref: SWEETRealm:Lava
is_a: ENVO:02000140 ! fluid environmental material
relationship: RO:0000086 PATO:0001305 ! has quality increased temperature
relationship: RO:0001000 ENVO:01000648 ! derives from magma

[Term]
id: ENVO:01000237
name: coastal scrubland
def: "A coastal scrubland is a scrubland which is part of a coast." [https://en.wikipedia.org/wiki/California_coastal_sage_and_chaparral_ecoregion, https://en.wikipedia.org/wiki/Coastal_sage_scrub]
is_a: ENVO:00000300 ! scrubland area
intersection_of: ENVO:00000300 ! scrubland area
intersection_of: BFO:0000050 ENVO:00000303 ! part of sea coast
relationship: BFO:0000050 ENVO:00000303 ! part of sea coast

[Term]
id: ENVO:01000242
name: desert scrubland
def: "A scrubland which is located in a desert." [ORCID:0000-0001-8743-9574]
synonym: "desert scrub" EXACT [ORCID:0000-0001-8743-9574]
is_a: ENVO:00000300 ! scrubland area
intersection_of: ENVO:00000300 ! scrubland area
intersection_of: RO:0000086 ENVO:01000230 ! has quality arid
intersection_of: RO:0002131 ENVO:00000097 ! overlaps desert area
relationship: RO:0000086 ENVO:01000230 ! has quality arid
relationship: RO:0002131 ENVO:00000097 ! overlaps desert area

[Term]
id: ENVO:01000245
name: cropland biome
def: "A cropland ecosystem which is undergoing climactic ecological succession." [http://dx.doi.org/10.1111/j.1466-8238.2010.00540.x, http://dx.doi.org/10.1890/070062]
is_a: ENVO:01000219 ! anthropogenic terrestrial biome
is_a: ENVO:01001244 ! cropland ecosystem
intersection_of: ENVO:01001244 ! cropland ecosystem
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:01000246
name: village biome
def: "A village biome is an anthropogenic terrestrial biome which contains settlements such as villages, towns, and/or small cities and which is primarily used for agricultural activity." [DOI:10.1111/j.1466-8238.2010.00540.x, DOI:10.1890/070062]
comment: Villages are also described as agricultural settlements with greater than 100 persons per square kilometre; however, no upper limit is defined.
is_a: ENVO:00000428 ! biome
is_a: ENVO:01000773 ! village
intersection_of: ENVO:01000773 ! village
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:01000247
name: rangeland biome
def: "A rangeland biome is an anthropogenic terrestrial biome which is primarily used for the rearing and grazing of livestock." [DOI:10.1111/j.1466-8238.2010.00540.x, DOI:10.1890/070062]
is_a: ENVO:01000219 ! anthropogenic terrestrial biome

[Term]
id: ENVO:01000248
name: dense settlement biome
def: "A dense settlement biome is an anthropogenic terrestrial biome which is primarily used for human habitation, recreation, and industry within built structures with little other land use." [DOI:10.1111/j.1466-8238.2010.00540.x, DOI:10.1890/070062]
is_a: ENVO:00000428 ! biome
is_a: ENVO:01000658 ! dense settlement
intersection_of: ENVO:01000658 ! dense settlement
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:01000249
name: urban biome
def: "An urban biome is a dense settlement biome which has been urbanised." [DOI:10.1111/j.1466-8238.2010.00540.x, DOI:10.1890/070062]
xref: SPIRE:Urban
is_a: ENVO:01000248 ! dense settlement biome

[Term]
id: ENVO:01000254
name: environmental system
def: "A system which has the disposition to environ one or more material entities." [DOI:10.1186/2041-1480-4-43]
comment: In ENVO's alignment with the Basic Formal Ontology, this class is being considered as a subclass of a proposed BFO class "system". The relation "environed_by" is also under development. Roughly, a system which includes a material entity (at least partially) within its site and causally influences that entity may be considered to environ it. Following the completion of this alignment, this class' definition and the definitions of its subclasses will be revised.
synonym: "environment" EXACT []
xref: EcoLexicon:environment
is_a: RO:0002577 ! system

[Term]
id: ENVO:01000256
name: mineral material
def: "A mineral material is an environmental material which is primarily composed of some substance that is naturally occurring, solid and stable at room temperature, representable by a chemical formula, usually abiogenic, and that has an ordered atomic structure." [https://en.wikipedia.org/wiki/Mineral]
xref: LTER:341
is_a: ENVO:01000814 ! solid environmental material
intersection_of: ENVO:00010483 ! environmental material
intersection_of: RO:0002473 CHEBI:46662 ! composed primarily of mineral
relationship: RO:0002473 CHEBI:46662 ! composed primarily of mineral

[Term]
id: ENVO:01000266
name: water vapour
def: "Water vapour is a vapour which is the gas phase of water." [https://en.wikipedia.org/wiki/Water_vapor]
comment: Perhaps a better relation between water vapour and water can be found in or added to RO?
synonym: "aqueous vapor" EXACT [https://en.wikipedia.org/wiki/Water_vapor]
synonym: "aqueous vapour" EXACT [https://en.wikipedia.org/wiki/Water_vapor]
synonym: "water vapor" EXACT [https://en.wikipedia.org/wiki/Water_vapor]
is_a: ENVO:01000797 ! gaseous environmental material
relationship: RO:0002473 CHEBI:15377 ! composed primarily of water

[Term]
id: ENVO:01000267
name: atmosphere
def: "An atmosphere is a layer of gases surrounding a material body of sufficient mass that is held in place by the gravity of the body." [https://en.wikipedia.org/wiki/Atmosphere, https://en.wikipedia.org/wiki/Physical_geography]
xref: LTER:48
is_a: ENVO:01001678 ! fluid layer
relationship: RO:0002220 ENVO:01000799 ! adjacent to astronomical body

[Term]
id: ENVO:01000268
name: atmospheric water vapour
def: "Atmospheric water vapour is water vapour that is part of an atmosphere." [https://en.wikipedia.org/wiki/Water_vapor]
synonym: "atmospheric water vapor" EXACT [https://en.wikipedia.org/wiki/Water_vapor]
is_a: ENVO:01000266 ! water vapour
intersection_of: ENVO:01000266 ! water vapour
intersection_of: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: RO:0000087 CHEBI:76413 ! has role greenhouse gas

[Term]
id: ENVO:01000271
name: clastic sedimentary rock
def: "Clastic sedimentary rocks are sedimentary rocks that are composed of silicate minerals and rock fragments that were transported by moving fluids. Clastic rocks are composed largely of quartz, feldspar, rock (lithic) fragments, clay minerals, and mica; numerous other minerals may be present as accessories and may be important locally." [https://en.wikipedia.org/wiki/Sedimentary_rock#Clastic_sedimentary_rocks]
is_a: ENVO:00002016 ! sedimentary rock

[Term]
id: ENVO:01000274
name: slate
def: "Slate is a metamorphic rock which is fine-grained, foliated, homogeneous, Slates are derived from clastic sedimentary rocks." [https://en.wikipedia.org/wiki/Slate]
is_a: ENVO:00002017 ! metamorphic rock
relationship: RO:0001000 ENVO:01000271 ! derives from clastic sedimentary rock

[Term]
id: ENVO:01000277
name: water ice
def: "Ice which is formed from water." [https://en.wikipedia.org/wiki/Ice]
comment: Water ice can appear transparent or opaque bluish-white color, depending on the presence of impurities or air inclusions. The addition of other materials such as soil may further alter its appearance.\n\nWhen speaking about ice on Earth, usually water ice is meant - the solid, crystalline form of water found in the atmosphere as snow crystals, hail, ice pellets, etc., and on the earth's surface in forms such as hoarfrost, rime, glaze, sea ice, glacier ice, ground ice, frazil, anchor ice, etc.\n\nThis form of water is, strictly speaking, called ice Ih, the Roman numeral I distinguishing it from more than a dozen other phases and the letter h distinguishing it from the metastable cubic phase ice Ic. Ice Ih is the only one of the several known phases of water ice that is stable at commonly occurring temperatures and pressures. (Some of the other forms have very unusual properties, ice VII, for example, being stable only at pressures above 22 400 kg/cm^2, but then existing at temperatures up to about 100C.)\n\nIt has an open structure with a specific gravity of 0.9166 which is slightly less than water; because the water molecules bond to their neighbors covalently only in four directions; it therefore floats on higher density water, where broken molecular bonds permit closer packing. All commonly occurring forms of ice are crystalline, although large single crystals are relatively rare except in glaciers. The ice crystal lattice possesses hexagonal symmetry that manifests itself in the gross forms of such single crystals as are sometimes found in snow. At an air pressure of one atmosphere, ice melts at 0 C by definition of the Celsius temperature scale. (Strictly speaking the equilibrium point among water, ice, and vapor occurs at +0.01C, the triple point.) On the other hand, ice does not invariably form in liquid water cooled below this temperature; it has a tendency to supercool, more so in the absence of ice nuclei.\n\nIn permafrost regions, ice may occupy voids in soils and rocks and may develop in a variety of forms. Ice may be colourless to pale blue or greenish-blue. It may appear white due to included gas bubbles; in exposures, ground ice may also appear black.\n\nIn nature ice is formed either by: (a) the freezing of water, (b) the condensation of atmospheric water vapour direct into ice crystals, (c) the compaction of snow with or without the motion of a glacier, or (d) the impregnation of porous snow masses with water which subsequently freeze.
xref: http://sweetontology.net/matrWater/Ice
xref: LTER:262
is_a: ENVO:01001125 ! ice
intersection_of: ENVO:01001125 ! ice
intersection_of: RO:0002473 CHEBI:15377 ! composed primarily of water
relationship: RO:0002473 CHEBI:15377 ! composed primarily of water

[Term]
id: ENVO:01000281
name: layer
def: "A material entity which 1) is spatially continuous, 2) is composed of material of comparable thickness, composition, and physical properties, and 3) is physically distinct from adjacent portions of environmental material." [https://en.wiktionary.org/wiki/layer]
is_a: BFO:0000040 ! material entity
relationship: RO:0000086 PATO:0000689 ! has quality continuous
relationship: RO:0000086 PATO:0002124 ! has quality laminar

[Term]
id: ENVO:01000283
name: lake layer
def: "A layer which is part of a lake." []
comment: Note that this class does not contain metalimnion as a subclass. The metaliminon is classified as a thermocline.
is_a: ENVO:01000325 ! aquatic layer
is_a: ENVO:01001308 ! hydroform
intersection_of: ENVO:01000325 ! aquatic layer
intersection_of: BFO:0000050 ENVO:00000020 ! part of lake
relationship: BFO:0000050 ENVO:00000020 ! part of lake

[Term]
id: ENVO:01000293
name: ice mass
def: "A mass of water ice." []
xref: http://sweetontology.net/phenCryo/Accumulation
is_a: ENVO:01001687 ! mass of solid material
is_a: ENVO:03000110 ! cryoform
intersection_of: ENVO:01001687 ! mass of solid material
intersection_of: RO:0002473 ENVO:01000277 ! composed primarily of water ice
relationship: BFO:0000050 ENVO:03000143 ! part of cryosphere
relationship: RO:0002473 ENVO:01000277 ! composed primarily of water ice

[Term]
id: ENVO:01000295
name: marine layer
def: "A layer that is part of a marine water body." [ORCID:0000-0002-4366-3088]
is_a: ENVO:01000325 ! aquatic layer
is_a: ENVO:01001308 ! hydroform
relationship: BFO:0000050 ENVO:00001999 ! part of marine water body
relationship: RO:0002473 ENVO:00002149 ! composed primarily of sea water

[Term]
id: ENVO:01000297
name: freshwater river
def: "A river where fresh water flows." [ORCID:0000-0002-4366-3088]
comment: Preliminary definition.
is_a: ENVO:00000022 ! river
is_a: ENVO:03605007 ! freshwater stream
intersection_of: ENVO:00000022 ! river
intersection_of: BFO:0000051 ENVO:00002011 ! has part fresh water

[Term]
id: ENVO:01000301
name: estuarine water
def: "Brackish water which is part of an estuary." [https://en.wikipedia.org/wiki/Estuary]
is_a: ENVO:00002019 ! brackish water
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:00002019 ! brackish water
intersection_of: BFO:0000050 ENVO:00002137 ! part of brackish estuary
relationship: BFO:0000050 ENVO:00002137 ! part of brackish estuary

[Term]
id: ENVO:01000303
name: endolithic environment
def: "An endolithic environment is an environment that exists within solid rock." []
is_a: ENVO:01000254 ! environmental system
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002219 ENVO:00001995 ! surrounded by rock
relationship: RO:0002219 ENVO:00001995 ! surrounded by rock

[Term]
id: ENVO:01000304
name: high pressure environment
def: "A high pressure environment is an environment in which all material entities are exposed to a high ratio of force per unit area." []
is_a: ENVO:01000997 ! environmental system determined by a quality
intersection_of: ENVO:01000997 ! environmental system determined by a quality
intersection_of: RO:0000086 PATO:0001576 ! has quality increased pressure
relationship: RO:0000086 PATO:0001576 ! has quality increased pressure

[Term]
id: ENVO:01000305
name: high temperature environment
def: "A high temperature environment is an environment in which material entities are exposed to increased levels of heat radiation or which have molecules or atoms moving randomly with increased levels of average kinietic energy." []
is_a: ENVO:01000997 ! environmental system determined by a quality
intersection_of: ENVO:01000997 ! environmental system determined by a quality
intersection_of: RO:0000086 PATO:0001305 ! has quality increased temperature
relationship: RO:0000086 PATO:0001305 ! has quality increased temperature

[Term]
id: ENVO:01000306
name: freshwater environment
def: "An aquatic environment which is determined by freshwater." []
synonym: "fresh water environment" EXACT []
is_a: ENVO:01000317 ! aquatic environment
intersection_of: ENVO:01000317 ! aquatic environment
intersection_of: RO:0002507 ENVO:00002011 ! determined by fresh water
relationship: RO:0002507 ENVO:00002011 ! determined by fresh water

[Term]
id: ENVO:01000307
name: saline water environment
def: "An environmental system which has its properties and dynamics determined by saline water." []
is_a: ENVO:01000317 ! aquatic environment
is_a: ENVO:01001040 ! saline environment
intersection_of: ENVO:01000317 ! aquatic environment
intersection_of: RO:0002507 ENVO:00002010 ! determined by saline water
relationship: RO:0002507 ENVO:00002010 ! determined by saline water

[Term]
id: ENVO:01000309
name: cold environment
def: "An environment which has a lower temperature than some local or global average." []
comment: The definition of the deprecated 'cold temperature habitat' class, which this class was derived from, quotes an upper threshold of 15 degrees Celsius for 'coldness'.
is_a: ENVO:01000254 ! environmental system
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0000086 PATO:0001306 ! has quality decreased temperature
relationship: RO:0000086 PATO:0001306 ! has quality decreased temperature

[Term]
id: ENVO:01000313
name: anthropogenic environment
def: "An anthropogenic environment is an environmental system which is the product of human activity." []
comment: Unsatisfactory definition here. Must consider the threshold that makes an environmental system anthropogenic.
is_a: ENVO:01000254 ! environmental system
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002354 ENVO:01000952 ! formed as result of anthropisation
relationship: RO:0002354 ENVO:01000952 ! formed as result of anthropisation

[Term]
id: ENVO:01000314
name: high osmolarity environment
def: "A high osmolarity environment is an environment in which entities are exposed to high concentrations of solutes." []
is_a: ENVO:01000997 ! environmental system determined by a quality
intersection_of: ENVO:01000997 ! environmental system determined by a quality
intersection_of: RO:0000086 PATO:0001657 ! has quality increased osmolarity
relationship: RO:0000086 PATO:0001657 ! has quality increased osmolarity

[Term]
id: ENVO:01000315
name: acidic environment
def: "An acidic environment is an environment in which material entities are exposed to a low pH." []
is_a: ENVO:01000997 ! environmental system determined by a quality

[Term]
id: ENVO:01000317
name: aquatic environment
def: "An environment whose dynamics are strongly influenced by water." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:01000998 ! environmental system determined by a material
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 ENVO:00002006 ! determined by liquid water
relationship: RO:0002507 ENVO:00002006 ! determined by liquid water

[Term]
id: ENVO:01000318
name: extreme high temperature environment
def: "An extreme high temperature environment is a high temperature environment in which entities are exposed to temperatures above 80 degrees Celsius." []
comment: The lower threshold, 80 degrees Celsius, is derived from the definition of the obsolete class "extreme high temperature habitat" which this class replaces.
is_a: ENVO:01000305 ! high temperature environment

[Term]
id: ENVO:01000319
name: rocky slope
def: "A rocky slope is a slope which has a surface primarily composed of rock." []
is_a: ENVO:00002000 ! slope

[Term]
id: ENVO:01000320
name: marine environment
def: "A marine environment and enviroment which is determined by a marine water body." [NM:nm]
is_a: ENVO:01000254 ! environmental system
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 ENVO:00001999 ! determined by marine water body
relationship: RO:0002507 ENVO:00001999 ! determined by marine water body

[Term]
id: ENVO:01000321
name: sea water environment
def: "An environmental system determined by seawater." []
synonym: "ocean water environment" EXACT []
is_a: ENVO:01000307 ! saline water environment
intersection_of: ENVO:01000307 ! saline water environment
intersection_of: RO:0002507 ENVO:00002149 ! determined by sea water
relationship: RO:0002507 ENVO:00002149 ! determined by sea water

[Term]
id: ENVO:01000322
name: brackish water environment
def: "An environment determined by the presence of brackish water." []
comment: This may refer to environments submerged in brackish water or those that are determined by its presence, such as a brackish water pond environment.
is_a: ENVO:01000307 ! saline water environment
intersection_of: ENVO:01000307 ! saline water environment
intersection_of: RO:0002507 ENVO:00002019 ! determined by brackish water
relationship: RO:0002507 ENVO:00002019 ! determined by brackish water

[Term]
id: ENVO:01000323
name: atmospheric boundary layer
def: "The atmospheric boundary layer is the lowest layer of an atmosphere which is strongly influenced by its contact with a planetary surface with strong vertical mixing and in which physical quantities such as flow velocity, temperature, and moisture display rapid fluctuations (turbulence)." []
synonym: "planetary boundary layer" EXACT []
is_a: ENVO:01000543 ! atmospheric layer
is_a: ENVO:01000544 ! boundary layer
relationship: RO:0002007 ENVO:01000267 ! bounding layer of atmosphere
relationship: RO:0002220 ENVO:01000324 ! adjacent to planetary surface

[Term]
id: ENVO:01000324
name: planetary surface
def: "A planetary surface is a surface layer where the solid or liquid material of a planet comes into contact with an atmosphere or outer space." []
comment: a useful class: this can be used to define sub-terrestrial and sub-marine entities
is_a: ENVO:01001483 ! surface of an astronomical body
intersection_of: ENVO:01001483 ! surface of an astronomical body
intersection_of: BFO:0000050 ENVO:01000800 ! part of planet
relationship: BFO:0000050 ENVO:01000800 ! part of planet

[Term]
id: ENVO:01000325
name: aquatic layer
def: "A layer in a water mass, itself composed primarily of water." []
comment: This class will eventually be populated by inference, and its asserted subclasses removed.
is_a: ENVO:01001273 ! liquid layer
intersection_of: ENVO:01001273 ! liquid layer
intersection_of: RO:0002473 ENVO:00002006 ! composed primarily of liquid water
relationship: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01000332
name: gravelly slope
def: "A gravelly slope is a slope which has a surface primarily composed of gravel." []
is_a: ENVO:00002000 ! slope

[Term]
id: ENVO:01000334
name: talus slope
def: "A talus slope is a slope which has a surface layer composed of scree." []
synonym: "scree slope" EXACT []
is_a: ENVO:00002000 ! slope

[Term]
id: ENVO:01000352
name: field
def: "An unbroken expanse (as of ice)" [http://www.merriam-webster.com/dictionary/field]
comment: This class was created to accommodate "fields" from agricultural fields to marine mesoscale eddy fields. Thus, it has a very broad definition which makes it less than informative when annotating. Please consider using or requesting an appropriate subclass.
is_a: ENVO:01000813 ! astronomical body part

[Term]
id: ENVO:01000355
name: vegetation layer
def: "A layer which is determined by a form of vegetation." []
comment: Usually found in woodlands and forests.
is_a: ENVO:01000281 ! layer
intersection_of: ENVO:01000281 ! layer
intersection_of: RO:0002473 NCBITaxon:33090 ! composed primarily of Viridiplantae
relationship: RO:0002473 NCBITaxon:33090 ! composed primarily of Viridiplantae

[Term]
id: ENVO:01000358
name: acidic water
def: "A portion of acidic water is a portion of water with a pH less than 7." []
is_a: ENVO:00002006 ! liquid water
intersection_of: ENVO:00002006 ! liquid water
intersection_of: RO:0000086 PATO:0001429 ! has quality acidic
relationship: RO:0000086 PATO:0001429 ! has quality acidic

[Term]
id: ENVO:01000371
name: agricultural waste material
def: "Agricultural waste is waste produced as a result of various agricultural operations. It includes manure and other wastes from farms, poultry houses and slaughterhouses; harvest waste; fertilizer run- off from fields; pesticides that enter into water, air or soils; and salt and silt drained from fields." [http://stats.oecd.org/glossary/detail.asp?ID=77, ISBN:978-92-1-161386-5]
comment: As with other wastes, this is more a role than a material in itself. This should be revised.
is_a: ENVO:00002264 ! waste material

[Term]
id: ENVO:01000373
name: biological waste material
def: "Biological waste is waste containing mostly natural organic materials (remains of plants, animal excrement, biological sludge from waste-water treatment plants and so forth)." [http://stats.oecd.org/glossary/detail.asp?ID=3097, ISBN:978-92-1-161386-5]
is_a: ENVO:00002264 ! waste material
relationship: RO:0002473 ENVO:00002873 ! composed primarily of organic waste material

[Term]
id: ENVO:01000405
name: respirable suspended particulate matter
def: "A portion of respirable suspended particulate matter is a form of particulate matter composed primarily of solid particles each with a diameter of 10 micrometers or less." [https://en.wikipedia.org/wiki/Particulates]
synonym: "PM10" EXACT []
is_a: ENVO:01001089 ! aerosolised solids
is_a: ENVO:01001646 ! amorphous solid

[Term]
id: ENVO:01000406
name: snow
def: "Snow is an environmental material which is primarily composed of flakes of crystalline water ice." [http://www.eionet.europa.eu/gemet/concept/7769, https://en.wikipedia.org/wiki/Snow]
is_a: ENVO:00010483 ! environmental material
relationship: BFO:0000051 ENVO:00002005 ! has part air
relationship: RO:0002353 ENVO:01000895 ! output of snowfall
relationship: RO:0002473 ENVO:01000277 ! composed primarily of water ice

[Term]
id: ENVO:01000408
name: environmental zone
def: "A site which has its extent determined by the presence or influence of one or more components of an environmental system or the processes occurring therein." []
comment: Formerly, this class was an experimental class and a subclass of "environmental feature". It is now aligned to BFO. The class was not obsoleted as the core semantics maintained their stability through its transition.
is_a: BFO:0000024 ! fiat object part
relationship: BFO:0000050 ENVO:01000254 ! part of environmental system

[Term]
id: ENVO:01000415
name: fine respirable suspended particulate matter
def: "A portion of fine respirable suspended particulate matter is a form of particulate matter composed primarily of solid particles each with a diameter of 2.5 micrometers or less." [https://en.wikipedia.org/wiki/Particulates]
synonym: "PM2.5" EXACT []
is_a: ENVO:01000405 ! respirable suspended particulate matter

[Term]
id: ENVO:01000416
name: ultrafine respirable suspended particulate matter
def: "A portion of fine respirable suspended particulate matter is a form of particulate matter composed primarily of solid particles each with a diameter of  100 nanometers or less." [https://en.wikipedia.org/wiki/Particulates, https://en.wikipedia.org/wiki/Ultrafine_particle]
comment: Regulations do not exist for this size class of ambient air pollution particles, which are far smaller than the regulated PM10 and PM2.5 particle classes and are believed to have several more aggressive health implications than those classes of larger particulates.
is_a: ENVO:01000415 ! fine respirable suspended particulate matter

[Term]
id: ENVO:01000420
name: building part
def: "A building part is a construction which is part of a building." []
comment: Not recommended for annotation. This class is likely to be made into an inferred class as its subclasses are distributed among more meaningful superclasses (i.e. ceiling is_a surface layer). See for example, "building floor". The boundaries between building parts may be bona fide or fiat.
is_a: ENVO:00000070 ! human construction
relationship: BFO:0000050 ENVO:00000073 ! part of building

[Term]
id: ENVO:01000426
name: room
def: "A building part which is separated from other building parts by one or more interior walls and, optionally, outdoor areas by one or more exterior walls." [https://en.wikipedia.org/wiki/Room]
is_a: ENVO:01000420 ! building part

[Term]
id: ENVO:01000436
name: waterborne particulate matter
def: "Particulate environmental material in which small portions of solid material are surrounded by water." []
is_a: ENVO:01000060 ! particulate environmental material
relationship: RO:0002219 ENVO:00002006 ! surrounded by liquid water
relationship: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material

[Term]
id: ENVO:01000451
name: atmospheric carbon dioxide
def: "Atmospheric carbon dioxide is an environmental material composed of carbon dioxide in its gaseous form present in an atmosphere." []
comment: This could also be considered a part of an environmental material like air.
is_a: ENVO:01000797 ! gaseous environmental material
relationship: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: RO:0002473 CHEBI:16526 ! composed primarily of carbon dioxide

[Term]
id: ENVO:01000452
name: environmental disposition
def: "A disposition which is realised by an environmental system or system parts thereof." []
comment: This class and its subclasses are experimental and are being developed with NCEAS use cases in mind.
is_a: BFO:0000016 ! disposition

[Term]
id: ENVO:01000457
name: masonry unit
def: "A masonry unit is a solid piece of material, usually with a regular shape, used as a component in the construction of buildings. Masonry units are usually composed of brick, stone, marble, granite, travertine, limestone, cast stone, concrete block, glass block, stucco, tile, or cob." [https://en.wikipedia.org/wiki/Masonry]
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:01000458
name: concrete
def: "Concrete is a composite material composed of an aggregate bonded together with a fluid cement which hardens over time." [https://en.wikipedia.org/wiki/Concrete]
comment: Missing the class for "aggregate" - tricky to define what it is, exactly. Again, seems more like some sort of material/disposition hybrid.
is_a: ENVO:0010001 ! anthropogenic environmental material
relationship: BFO:0000051 ENVO:01000462 ! has part masonry cement

[Term]
id: ENVO:01000459
name: asphalt concrete
def: "Asphaltic concrete is a concrete which uses refined asphalt as a cement." [https://en.wikipedia.org/wiki/Concrete]
synonym: "asphaltic concrete" EXACT []
synonym: "road pavement" EXACT []
is_a: ENVO:01000458 ! concrete
relationship: BFO:0000051 ENVO:01000461 ! has part refined asphalt

[Term]
id: ENVO:01000460
name: asphalt
def: "Asphalt also known as bitumen is a sticky, black, and highly viscous liquid or semi-solid form of petroleum." [https://en.wikipedia.org/wiki/Asphalt]
comment: This class refers to naturally-occuring asphalt or bitumen.
synonym: "asphaltum" EXACT []
synonym: "bitumen" EXACT []
synonym: "crude bitumen" EXACT []
is_a: ENVO:00002984 ! petroleum

[Term]
id: ENVO:01000461
name: refined asphalt
def: "Refined asphalt is a sticky, black, and highly viscous liquid or semi-solid with a boiling point above 500 degrees Celsius, obtained from the fractional distillation of crude oil." [https://en.wikipedia.org/wiki/Asphalt]
synonym: "refined bitumen" EXACT []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:01000815 ! liquid environmental material
relationship: RO:0001000 ENVO:00002984 ! derives from petroleum

[Term]
id: ENVO:01000462
name: masonry cement
def: "Masonry cement is a substance used in construction that has the disposition to set and harden and thus may be used to bind materials together." [https://en.wikipedia.org/wiki/Cement]
comment: "Cement" refers more to a disposition than a specific material.
is_a: ENVO:0010001 ! anthropogenic environmental material

[Term]
id: ENVO:01000474
name: brick material
def: "A portion of brick material is a material derived from a brick which is composed of  kneaded clay-bearing soil, expanded clay aggregate, sand and lime, or concrete that has been fire-hardened or air-dried." [https://en.wikipedia.org/wiki/Brick]
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:01000814 ! solid environmental material

[Term]
id: ENVO:01000475
name: brick
def: "A brick is a masonry unit which is composed of kneaded clay-bearing soil, expanded clay aggregate, sand and lime, or concrete material, fire-hardened or air-dried." [https://en.wikipedia.org/wiki/Brick]
comment: Generally used to refer to the masonry unit rather than a material.
is_a: ENVO:01000457 ! masonry unit

[Term]
id: ENVO:01000476
name: plaster
def: "Plaster is a building material which has the disposition to harden when it reacts with water, liberating heat through crystallization. Plaster is manufactured as a dry powder and is mixed with water to form a paste when used." [https://en.wikipedia.org/wiki/Plaster]
synonym: "render" EXACT []
synonym: "stucco" EXACT []
is_a: ENVO:0010001 ! anthropogenic environmental material

[Term]
id: ENVO:01000478
name: cement plaster
synonym: "cement render" EXACT []
synonym: "cement stucco" EXACT []
is_a: ENVO:01000476 ! plaster

[Term]
id: ENVO:01000479
name: lime plaster
def: "Lime plaster is a plaster which is primarily composed of calcium hydroxide and an inert filler (such as sand). Coversion of the calcium hydroxide to calcium carbonate through a reaction with carbon dioxide in the air causes the plaster to set." [https://en.wikipedia.org/wiki/Plaster]
synonym: "lime render" EXACT []
synonym: "lime stucco" EXACT []
synonym: "slaked lime plaster" EXACT []
is_a: ENVO:01000476 ! plaster

[Term]
id: ENVO:01000480
name: glass
def: "Glass is an amorphous (non-crystalline) solid which is often transparent." [https://en.wikipedia.org/wiki/Glass]
comment: This class refers to all forms of glass. For the familiar form present in window panes and drinking glasses, consider silica-based glass.
is_a: ENVO:01000814 ! solid environmental material

[Term]
id: ENVO:01000486
name: building floor
def: "A building floor is a surface layer which is part of a building and used for walking." []
comment: To be more precise, a subfloor and a floor covering may be specified. Please request these classes and propose definitions if they are needed.
is_a: ENVO:00000191 ! solid astronomical body part
is_a: ENVO:01001311 ! solid surface layer
is_a: ENVO:01001483 ! surface of an astronomical body
relationship: BFO:0000050 ENVO:00000073 ! part of building

[Term]
id: ENVO:01000488
name: wooden building floor
def: "A wooden building floor is a building floor that is composed primarily of wood." []
is_a: ENVO:01000486 ! building floor
is_a: ENVO:01001271 ! impermeable surface layer
relationship: RO:0002473 ENVO:00002040 ! composed primarily of wood

[Term]
id: ENVO:01000489
name: concrete building floor
def: "A concrete building floor is a building floor that is composed primarily of concrete" []
comment: At times, this is called a cement floor, although that is probably not accurate.
is_a: ENVO:01000486 ! building floor
is_a: ENVO:01001271 ! impermeable surface layer
relationship: RO:0002473 ENVO:01000458 ! composed primarily of concrete

[Term]
id: ENVO:01000536
name: factory
def: "A factory (previously manufactory) or manufacturing plant is an industrial site, usually consisting of buildings and machinery, or more commonly a complex having several buildings, where workers manufacture goods or operate machines processing one product into another." [https://en.wikipedia.org/wiki/Factory]
synonym: "manufactory" EXACT []
synonym: "manufacturing plant" EXACT []
is_a: ENVO:00003861 ! industrial building
relationship: BFO:0000051 ENVO:00003861 ! has part industrial building

[Term]
id: ENVO:01000538
name: stratosphere
def: "The layer of the atmosphere which is sandwiched between the troposphere and mesosphere. Of the energy that reaches the Earth from the sun, only 3% is absorbed in the stratosphere, but that includes the vitally important process of absorption of ultraviolet radiation by the stratospheric ozone layer. The stratosphere is cloudless and dust free, and almost unaffected by the turbulent conditions of the underlying level of the atmosphere. (Source: WRIGHT)" [GEMET:http\://www.eionet.europa.eu/gemet/concept/8128]
comment: Definition from GEMET - will be refined.
is_a: ENVO:01000543 ! atmospheric layer

[Term]
id: ENVO:01000539
name: mesosphere
def: "The mesosphere is part of the earth's atmosphere which is between the stratosphere and the thermosphere in which temperature decreases with altitude to the atmosphere's absolute minimum" [http://www.merriam-webster.com/dictionary/mesosphere]
is_a: ENVO:01000543 ! atmospheric layer

[Term]
id: ENVO:01000540
name: troposphere
def: "The lowest of the concentric layers of the atmosphere, occurring between the Earth's surface and the tropopause. It is the zone where atmospheric turbulence is at its greatest and where the bulk of the Earth's weather is generated. It contains almost all the water vapour and aerosols and three-quarters of the total gaseous mass of the atmosphere. Throughout the troposphere temperature decreases with height at a mean rate of 6.5°C/km and the whole zone is capped by either an inversion of temperature or an isothermal layer at the tropopause. (Source: WHIT)" [GEMET:http\://www.eionet.europa.eu/gemet/concept/8695]
comment: Definition from GEMET - will be refined.
is_a: ENVO:01000543 ! atmospheric layer

[Term]
id: ENVO:01000541
name: thermosphere
def: "The thermosphere is a part of the earth's atmosphere that begins at about 50 miles (80 kilometers) above the earth's surface, extends to outer space, and is characterized by steadily increasing temperature with height" [http://www.merriam-webster.com/dictionary/thermosphere]
is_a: ENVO:01000543 ! atmospheric layer
relationship: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: RO:0002220 ENVO:01000539 ! adjacent to mesosphere

[Term]
id: ENVO:01000543
name: atmospheric layer
def: "A layer that is part of the atmosphere." []
comment: This could be made into an inferred class, rather than having asserted subclasses.
is_a: ENVO:01001678 ! fluid layer
intersection_of: ENVO:01001678 ! fluid layer
intersection_of: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: RO:0002473 ENVO:01000797 ! composed primarily of gaseous environmental material

[Term]
id: ENVO:01000544
name: boundary layer
def: "A boundary layer is a layer of fluid in the immediate vicinity of a bounding surface where the effects of viscosity are significant enough to distort the surrounding non-viscous flow." [https://en.wikipedia.org/wiki/Boundary_layer]
synonym: "boundary layer" EXACT [http://www.eionet.europa.eu/gemet/concept/976]
is_a: ENVO:01001677 ! fluid interface layer
relationship: RO:0002220 ENVO:00010504 ! adjacent to surface layer

[Term]
id: ENVO:01000547
name: glaze ice layer
def: "A glaze ice layer is a smooth, transparent and homogeneous ice layer which coats some surface and which is formed when freezing rain or drizzle hits that surface." [https://en.wikipedia.org/wiki/Glaze_ice]
is_a: ENVO:01001276 ! water ice layer
relationship: RO:0002354 ENVO:01000896 ! formed as result of freezing rainfall

[Term]
id: ENVO:01000552
name: natural gas
def: "Natural gas is a hydrocarbon gas mixture consisting primarily of methane, but commonly includes varying amounts of other higher alkanes and sometimes a usually lesser percentage of carbon dioxide, nitrogen, and/or hydrogen sulfide. Natural gas is a fossil fuel formed when layers of buried plants and gases are exposed to intense heat and pressure over thousands of years." [https://en.wikipedia.org/wiki/Natural_gas]
is_a: ENVO:01000554 ! hydrocarbon gas
relationship: RO:0000087 CHEBI:35230 ! has role fossil fuel
relationship: RO:0002473 CHEBI:16183 ! composed primarily of methane

[Term]
id: ENVO:01000553
name: liquefied petroleum gas
def: "Liquified petroleum gas or liquid petroleum gas (LPG or LP gas), also referred to as simply propane or butane, are flammable mixtures of hydrocarbon gases used as fuel in heating appliances, cooking equipment, and vehicles." [https://en.wikipedia.org/wiki/Liquefied_petroleum_gas]
synonym: "liquid petroleum gas" EXACT []
synonym: "LP gas" EXACT []
synonym: "LPG" EXACT []
is_a: ENVO:01000558 ! liquefied hydrocarbon gas

[Term]
id: ENVO:01000554
name: hydrocarbon gas
def: "A gas that is primarily composed of hydrocarbon molecules." []
is_a: ENVO:01000797 ! gaseous environmental material
is_a: ENVO:2000045 ! hydrocarbon-based environmental material
intersection_of: ENVO:01000797 ! gaseous environmental material
intersection_of: RO:0000086 PATO:0001547 ! has quality quality of a gas
intersection_of: RO:0002473 CHEBI:24632 ! composed primarily of hydrocarbon

[Term]
id: ENVO:01000557
name: liquefied natural gas
def: "Liquefied natural gas (LNG) is natural gas (predominantly methane, CH4) that has been converted to liquid form for ease of storage or transport. It takes up about 1/600th the volume of natural gas in the gaseous state. It is odorless, colorless, non-toxic and non-corrosive. LNG achieves a higher reduction in volume than compressed natural gas (CNG) so that the (volumetric) energy density of LNG is 2.4 times greater than that of CNG or 60 percent of that of diesel fuel." [https://en.wikipedia.org/wiki/Liquefied_natural_gas]
synonym: "liquified natural gas" EXACT []
synonym: "LNG" EXACT []
is_a: ENVO:01000558 ! liquefied hydrocarbon gas

[Term]
id: ENVO:01000558
name: liquefied hydrocarbon gas
is_a: ENVO:01000815 ! liquid environmental material
is_a: ENVO:2000045 ! hydrocarbon-based environmental material
relationship: RO:0000086 PATO:0001485 ! has quality condensed
relationship: RO:0000086 PATO:0001576 ! has quality increased pressure

[Term]
id: ENVO:01000560
name: charcoal
def: "Charcoal is a light, black residue, consisting of carbon and any remaining ash, obtained by removing water and other volatile constituents from animal and vegetation substances. Charcoal is usually produced by slow pyrolysis, the heating of wood or other substances in the absence of oxygen." [https://en.wikipedia.org/wiki/Charcoal]
is_a: ENVO:01000155 ! organic material
is_a: ENVO:01000814 ! solid environmental material
is_a: ENVO:2000045 ! hydrocarbon-based environmental material
relationship: RO:0002353 ENVO:01000841 ! output of pyrolysis

[Term]
id: ENVO:01000575
name: wax
def: "A wax is an environmental material which is primarily composed of lipids or other organic compounds that consist of long alkyl chains. Waxes are are malleable near ambient temperatures and melt at approximately 45 degrees Celsius." [https://en.wikipedia.org/wiki/Wax]
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:01000599
name: river water
is_a: ENVO:03605006 ! stream water
relationship: BFO:0000050 ENVO:00000022 ! part of river

[Term]
id: ENVO:01000604
name: vehicle
def: "A vehicle is a mobile machine which transports people or cargo." [https://en.wikipedia.org/wiki/Vehicle]
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:01000617
name: lentic water body
def: "A lentic water body is a water body in which the accumulated water, in its totality, has very little to no directed flow." []
is_a: ENVO:00000063 ! water body

[Term]
id: ENVO:01000618
name: lotic water body
def: "A lotic water body is a water body in which the accumulated water, in its totality, is flowing." []
is_a: ENVO:00000063 ! water body

[Term]
id: ENVO:01000624
name: hydrological condensation process
def: "Hydrological condensation is a process in which atmospheric water vapour undergoes a phase transition from the gas phase to the liquid phase." [https://en.wikipedia.org/wiki/Condensation]
comment: "process" is included in the label to make it clear that we are not referring to the condensed material (e.g. water droplets, window fog)
is_a: ENVO:01000724 ! condensation process
is_a: ENVO:02500031 ! hydrological process
relationship: RO:0002233 ENVO:01000268 ! has input atmospheric water vapour
relationship: RO:0002234 ENVO:00002006 ! has output liquid water

[Term]
id: ENVO:01000629
name: climate change
def: "The long-term fluctuations in temperature, precipitation, wind, and all other aspects of the Earth's climate. External processes, such as solar-irradiance variations, variations of the Earth's orbital parameters (eccentricity, precession, and inclination), lithosphere motions, and volcanic activity, are factors in climatic variation. Internal variations of the climate system, e.g., changes in the abundance of greenhouse gases, also may produce fluctuations of sufficient magnitude and variability to explain observed climate change through the feedback processes interrelating the components of the climate system." [GEMET:http\://www.eionet.europa.eu/gemet/concept/1471]
comment: Definition vebatim from GEMET. Will need to be refined. Further, distinction between "climate change" and (one or many) "climate change process" will need to be discussed. Fluctuations are not processes, per se.
is_a: ENVO:02500000 ! environmental system process
relationship: RO:0002233 ENVO:01001364 ! has input climate system

[Term]
id: ENVO:01000630
name: acidification of an aquatic environment
def: "Acidification of an aquatic environment is a process whereby the pH of an aquatic environment, biome, or water body is lowered." []
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:01000631
name: ocean acidification
def: "Ocean acidification is a process during which the pH of a sea or ocean is lowered." []
comment: On Earth, the major cause of ocean acidification is the update of carbon dioxide from the atmosphere.
xref: LTER:962 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=962&/ocean-acidification"}
is_a: ENVO:01000630 ! acidification of an aquatic environment

[Term]
id: ENVO:01000634
name: volcanic eruption
def: "A volcanic eruption is a process during which lava, tephra (ash, lapilli, volcanic bombs and blocks), and assorted gases are expelled from a volcanic vent or fissure." [https://en.wikipedia.org/wiki/Types_of_volcanic_eruptions]
is_a: ENVO:02500031 ! hydrological process
is_a: ENVO:03000010 ! material transport process
relationship: RO:0000057 ENVO:00000247 ! has participant volcano
relationship: RO:0000057 ENVO:01000638 ! has participant planetary crust
relationship: RO:0002233 ENVO:01000648 ! has input magma
relationship: RO:0002234 CHEBI:16136 ! has output hydrogen sulfide
relationship: RO:0002234 CHEBI:16526 ! has output carbon dioxide
relationship: RO:0002234 CHEBI:17245 ! has output carbon monoxide
relationship: RO:0002234 CHEBI:17883 ! has output hydrogen chloride
relationship: RO:0002234 CHEBI:18276 ! has output dihydrogen
relationship: RO:0002234 CHEBI:18422 ! has output sulfur dioxide
relationship: RO:0002234 ENVO:01000266 ! has output water vapour

[Term]
id: ENVO:01000635
name: planetary landmass
def: "A landmass which is part of a planet." [Adpated from https://en.wikipedia.org/wiki/Planetary_surface]
is_a: ENVO:01000324 ! planetary surface
is_a: ENVO:01001782 ! landmass

[Term]
id: ENVO:01000637
name: outer space
def: "Outer space is a hard vacuum containing a low density of particles, predominantly a plasma of hydrogen and helium as well as electromagnetic radiation, magnetic fields, neutrinos, dust and cosmic rays that exists between celestial bodies." [https://en.wikipedia.org/wiki/Outer_space]
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:01000638
name: planetary crust
def: "A planetary crust is the outermost solid shell of a rocky planet or natural satellite, which is chemically distinct from the underlying mantle." [https://en.wikipedia.org/wiki/Crust_(geology)]
comment: This class is meant to be applicable accross planets. Earth's crust would be an instance.
is_a: ENVO:01000639 ! planetary structural layer
relationship: RO:0000086 PATO:0001546 ! has quality quality of a solid

[Term]
id: ENVO:01000639
name: planetary structural layer
def: "A planetary structural layer is laminar part of a terrestrial planet or other rocky body large enough to have differentiation by density. Planetary layers have differing physicochemical properties and composition." []
is_a: ENVO:01000281 ! layer
is_a: ENVO:01000813 ! astronomical body part
relationship: BFO:0000050 ENVO:01000800 ! part of planet

[Term]
id: ENVO:01000640
name: planetary mantle
def: "A planetary mantle is a planetary layer which is an interior part of a terrestrial planet or other rocky body large enough to have differentiation by density." [https://en.wikipedia.org/wiki/Mantle_(geology)]
comment: This class is meant to be applicable accross planets. Earth's mantle would be an instance.
is_a: ENVO:01000639 ! planetary structural layer
relationship: RO:0002220 ENVO:01000638 ! adjacent to planetary crust

[Term]
id: ENVO:01000646
name: lithosphere
def: "A lithosphere is the outermost shell of a terrestrial-type planet or natural satellite that is defined by its rigid mechanical properties." [https://en.wikipedia.org/wiki/Lithosphere]
comment: Earth's lithosphere includes the crust and uppermost mantle.
is_a: ENVO:00000191 ! solid astronomical body part
is_a: ENVO:01000639 ! planetary structural layer
is_a: ENVO:01001275 ! solid layer
relationship: BFO:0000051 ENVO:01000638 ! has part planetary crust
relationship: RO:0000086 PATO:0001545 ! has quality inflexible

[Term]
id: ENVO:01000648
name: magma
def: "Magma is a mixture of molten or semi-molten rock, volatiles, and solids that is found beneath the uppermost solid layer of a planetary body. Besides molten rock, magma may also contain suspended crystals, dissolved gas and sometimes gas bubbles." [https://en.wikipedia.org/wiki/Magma]
is_a: ENVO:02000140 ! fluid environmental material
relationship: RO:0000086 PATO:0001305 ! has quality increased temperature
relationship: RO:0001025 ENVO:01000639 ! located in planetary structural layer

[Term]
id: ENVO:01000650
name: stream channel
def: "A channel of a watercourse which contains a stream." []
is_a: ENVO:00000395 ! channel of a watercourse
intersection_of: ENVO:00000395 ! channel of a watercourse
intersection_of: RO:0001015 ENVO:00000023 ! location of stream
relationship: RO:0001015 ENVO:00000023 ! location of stream

[Term]
id: ENVO:01000652
name: river channel
def: "A stream channel which contains a river." []
is_a: ENVO:01000650 ! stream channel
relationship: RO:0001015 ENVO:00000022 ! location of river

[Term]
id: ENVO:01000655
name: explosive eruption
def: "An explosive eruption is a volcanic process in which pressurised magma is violently expelled and froths into volcanic ash. Explosive eruptions can eject a cloud of rocks, dust, gas, and pyroclastic material  which may then collapse, creating a pyroclastic flow of hot volcanic matter." [https://en.wikipedia.org/wiki/Explosive_eruption]
is_a: ENVO:01000634 ! volcanic eruption

[Term]
id: ENVO:01000658
name: dense settlement
def: "A settlement with a high density of buildings and inhabitants." []
comment: The thresholds for what makes a settlment "dense" can be determined as needed. If there is a specific threshold that should be added to ENVO, please make a new class request.
is_a: ENVO:01001829 ! human settlement

[Term]
id: ENVO:01000660
name: tephra
def: "Tephra is fragmental material produced by a volcanic eruption regardless of composition, fragment size or emplacement mechanism." [https://en.wikipedia.org/wiki/Tephra]
is_a: ENVO:01000814 ! solid environmental material
relationship: RO:0000086 PATO:0001444 ! has quality broken
relationship: RO:0002353 ENVO:01000655 ! output of explosive eruption

[Term]
id: ENVO:01000665
name: waste role
def: "A role that is realized in some process wherein the bearer is discarded or not utilized further." []
is_a: BFO:0000023 ! role

[Term]
id: ENVO:01000667
name: geological fracture
def: "A geological fracture is any separation in a geologic formation, such as a joint or a fault that divides a mass of rock into two or more pieces." [https://en.wikipedia.org/wiki/Fracture_(geology)]
xref: SWEETRealm:Fissure
is_a: ENVO:00000191 ! solid astronomical body part

[Term]
id: ENVO:01000668
name: geological fault
def: "A geological fault is a planar fracture or discontinuity in a volume of rock, across which there has been significant displacement as a result of rock mass movement." []
comment: The relationship between faults and active plate boundaries must be further developed, as there is some overlap.
is_a: ENVO:01000667 ! geological fracture

[Term]
id: ENVO:01000669
name: active geological fault
def: "An active fault is a fault that is likely to become the source of another earthquake sometime in the future. Geologists commonly consider faults to be active if there has been movement observed or evidence of seismic activity during the last 10,000 years." []
synonym: "active fault" EXACT []
is_a: ENVO:01000668 ! geological fault
relationship: RO:0000056 ENVO:01001093 ! participates in tectonic movement

[Term]
id: ENVO:01000676
name: contaminated air
def: "Contaminated air is air which has sufficient concentrations of environmental pollutants such that it may adversely affect a given ecosystem." []
is_a: ENVO:00002005 ! air

[Term]
id: ENVO:01000677
name: earthquake
def: "An earthquake is a process during which energy is released in an astronomical body's crust, causing the displacement of crustal parts and the generation of seismic waves." [Adapted from URL:http\://www.britannica.com/science/earthquake-geology, https://en.wikipedia.org/wiki/Earthquake]
comment: Elastic strain, gravity, chemical reactions, or even the motion of massive bodies can produce earthquakes.
synonym: "quake" EXACT []
is_a: ENVO:03000010 ! material transport process

[Term]
id: ENVO:01000678
name: tectonic earthquake
def: "An earthquake caused by the sudden release of energy accumulated in an astronomical body's crust, as the elastic strain placed on constituent rock masses causes them to fracture." [URL:http\://www.britannica.com/science/earthquake-geology]
is_a: ENVO:01000677 ! earthquake
relationship: BFO:0000051 ENVO:01001767 ! has part structural collapse process
relationship: RO:0000057 ENVO:01000669 ! has participant active geological fault
relationship: RO:0002427 ENVO:01001093 ! causally downstream of or within tectonic movement

[Term]
id: ENVO:01000680
name: polluted lake
def: "A lake which has concentrations of environmental contaminants high enough to harm the ecosystems associated with it." []
is_a: ENVO:00000020 ! lake
intersection_of: ENVO:00000020 ! lake
intersection_of: RO:0002473 ENVO:00002186 ! composed primarily of contaminated water
relationship: RO:0002473 ENVO:00002186 ! composed primarily of contaminated water

[Term]
id: ENVO:01000685
name: water mass
def: "A mass of water." []
is_a: ENVO:01001476 ! body of liquid
relationship: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01000687
name: coast
def: "A coast is the area where land meets the sea, ocean, or lake." [https://en.wikipedia.org/wiki/Coast]
comment: Used for both marine and lake coasts. The boundary of the coast is fuzzy and it overlaps both the water body and land in quesiton. Compared to 'shore'
is_a: ENVO:01001784 ! compound astronomical body part
relationship: RO:0002131 ENVO:01000635 ! overlaps planetary landmass

[Term]
id: ENVO:01000689
name: tsunami
def: "A tsunami is a process during which a series of waves is generated in a water body, typically an ocean or large lake, by the displacement of a large volume of water. Earthquakes, volcanic eruptions and other underwater explosions (including detonations of underwater nuclear devices), landslides, glacier calvings, meteorite impacts and other disturbances above or below water all have the potential to generate a tsunami." [https://en.wikipedia.org/wiki/Tsunami]
synonym: "seismic sea wave" EXACT []
synonym: "tidal wave" EXACT []
is_a: ENVO:01000981 ! mass liquid flow

[Term]
id: ENVO:01000690
name: mass wasting
def: "Mass wasting is the geomorphic process by which solid environmental material such as soil, sand, regolith, and/or rock move downslope typically as a mass, largely under the force of gravity, but frequently affected by water and water content as in submarine environments and mudslides." [https://en.wikipedia.org/wiki/Mass_wasting]
comment: Of interest for future development: Some causes of mass wasting earthquakes, increased overburden from structures, increased soil moisture, reduction of roots holding the soil to bedrock, undercutting of the slope by excavation or erosion, weathering by frost heave, bioturbation, volcanic edifice over-steepening. Some processes that reduce mass wasting: Afforestation, Reforestation, Terracing steps on slopes (reduce angle of slope). https://en.wikipedia.org/wiki/Mass_wasting.
synonym: "slope movement" EXACT []
is_a: ENVO:03000010 ! material transport process
relationship: BFO:0000051 ENVO:03000009 ! has part material accumulation process
relationship: BFO:0000051 ENVO:03000016 ! has part material decumulation process
relationship: RO:0000057 ENVO:00002000 ! has participant slope

[Term]
id: ENVO:01000692
name: landslide process
def: "A landslide is a process whereby a large mass of earth and rocks moves down a hill or a mountainside." [https://en.wikipedia.org/wiki/Mass_wasting]
synonym: "landslip" EXACT []
xref: GEMET:http\://www.eionet.europa.eu/gemet/concept/4668
is_a: ENVO:01000690 ! mass wasting

[Term]
id: ENVO:01000695
name: mudslide
is_a: ENVO:01000690 ! mass wasting

[Term]
id: ENVO:01000701
name: volcanic ash
def: "Volcanic ash is an environmental material which consists of fragments of pulverized rock, minerals, and volcanic glass, created during volcanic eruptions and measuring less than 2 millimetres in diameter. Volcanic ash is formed during explosive volcanic eruptions, phreatomagmatic eruptions and during transport in pyroclastic density currents." [https://en.wikipedia.org/wiki/Volcanic_ash]
is_a: ENVO:02000090 ! ash
intersection_of: ENVO:02000090 ! ash
intersection_of: RO:0002353 ENVO:01000634 ! output of volcanic eruption
relationship: RO:0002353 ENVO:01000634 ! output of volcanic eruption
relationship: RO:0002473 CHEBI:30563 ! composed primarily of silicon dioxide

[Term]
id: ENVO:01000703
name: hydrological precipitation process
def: "Hydrological precipitation is a process during which any product of the condensation of atmospheric water vapour is pulled to the planetary surface by gravity." [https://en.wikipedia.org/wiki/Precipitation]
comment: "process" is included in the label to make it clear that we are not referring to the precipitated material (e.g. snow, rain, sleet)
is_a: ENVO:01000875 ! precipitation process

[Term]
id: ENVO:01000705
name: soil degradation
def: "Soil degradation is a process which results in a change in soil health status resulting in a diminished capacity of the ecosystem in which the soil occurs to provide goods and services for its  beneficiaries." [FAO:http\://www.fao.org/soils-portal/soil-degradation-restoration/en/]
is_a: ENVO:02500005 ! land degradation

[Term]
id: ENVO:01000707
name: coastal flooding
def: "Coastal flooding is a process in which normally dry, low-lying land near a coast is flooded by sea water." [https://en.wikipedia.org/wiki/Coastal_flood]
is_a: ENVO:02500002 ! flooding
relationship: RO:0000057 ENVO:01000687 ! has participant coast

[Term]
id: ENVO:01000708
name: riverine flooding
def: "Riverine flooding is a process in which the flow rate of river water exceeds the capacity of its channel, thus flooding neighbouring land. Bends and meanders in a river channel are particularly disposed to such flooding." [https://en.wikipedia.org/wiki/Flood#Riverine]
is_a: ENVO:02500002 ! flooding

[Term]
id: ENVO:01000709
name: flash flooding
def: "Flash flooding is a process in which low-lying land is inundated with water for a short period of time and are usually the result of precipitation or a breach in the container of a water body." [https://en.wikipedia.org/wiki/Flash_flood]
comment: Flash floods generally last no more than six hours. http://www.srh.noaa.gov/mrx/hydro/flooddef.php
is_a: ENVO:02500002 ! flooding
relationship: RO:0000057 ENVO:00000309 ! has participant depressed landform

[Term]
id: ENVO:01000710
name: flood
def: "An unusual accumulation of water above the ground caused by high tide, heavy rain, melting snow or rapid runoff from paved areas." [GEMET:http\://www.eionet.europa.eu/gemet/concept/3298]
is_a: ENVO:00000063 ! water body
relationship: RO:0002354 ENVO:02500002 ! formed as result of flooding

[Term]
id: ENVO:01000711
name: coastal flood
def: "A coastal flood is a flood which is formed as a result of large amounts of water from marine water bodies or large lakes being transported to usually dry land by displacement processes such as high winds or seismic activity." [https://en.wikipedia.org/wiki/Flood#Estuarine_and_coastal]
is_a: ENVO:01000710 ! flood
relationship: RO:0002131 ENVO:01000687 ! overlaps coast
relationship: RO:0002354 ENVO:01000707 ! formed as result of coastal flooding

[Term]
id: ENVO:01000713
name: flash flood
def: "A flash flood is a flood formed by the rapid flooding of geomorphic low-lying areas. It may be caused by heavy rain associated with a severe thunderstorm, hurricane, tropical storm, or meltwater from ice or snow flowing over ice sheets or snowfields. Flash floods may also occur after the collapse of a natural ice or debris dam, or a human structure such as a man-made dam. Flash floods are distinguished from a regular flood by a timescale of less than six hours." [https://en.wikipedia.org/wiki/Flash_flood]
is_a: ENVO:01000710 ! flood
relationship: RO:0002354 ENVO:01000709 ! formed as result of flash flooding

[Term]
id: ENVO:01000714
name: storm surge
def: "A storm surge is a coastal flood which is caused by low-pressure weather systems such as tropical cyclones and strong extratropical cyclones, the severity of which is affected by the shallowness and orientation of the water body relative to storm path, and the timing of tides." [https://en.wikipedia.org/wiki/Storm_surge]
is_a: ENVO:01000711 ! coastal flood
relationship: RO:0002354 ENVO:01000716 ! formed as result of storm surge process

[Term]
id: ENVO:01000715
name: meteotsunami
def: "A meteotsunami is a tsunami caused by atmospheric processes and differences in air pressure." [https://en.wikipedia.org/wiki/Meteotsunami]
synonym: "rissaga" EXACT [] {comment="Language: Catalan"}
is_a: ENVO:01000689 ! tsunami

[Term]
id: ENVO:01000716
name: storm surge process
def: "A storm surge process is a coastal flooding process which is caused by low pressure weather systems such as tropical cyclones and strong extratropical cyclones, the severity of which is affected by the shallowness and orientation of the water body relative to storm path, and the timing of tides." [https://en.wikipedia.org/wiki/Storm_surge]
is_a: ENVO:01000707 ! coastal flooding

[Term]
id: ENVO:01000717
name: areal flooding
def: "Areal flooding is a flooding process in which flat or low-lying areas become inundated with water due to water input exceeding infiltration, evaporation, or run off." [https://en.wikipedia.org/wiki/Flood#Areal]
is_a: ENVO:02500002 ! flooding

[Term]
id: ENVO:01000718
name: urban flooding
def: "Urban flooding is a flooding process in which land or property in a built environment, particularly in more densely populated areas, is inundated due to the rate of water input exceeding that of water drainage provided by the environment's drainage systems." [https://en.wikipedia.org/wiki/Flood#Urban_flooding]
is_a: ENVO:02500002 ! flooding

[Term]
id: ENVO:01000724
name: condensation process
def: "Condensation is a process during which a gas undergoes a phase transition into a liquid." [https://en.wikipedia.org/wiki/Condensation]
is_a: ENVO:01001510 ! material congelation process

[Term]
id: ENVO:01000726
name: desublimation process
def: "Desublimation is a process in which a portion of some gas undergoes a phase transition into a portion of some solid." [https://en.wikipedia.org/wiki/Deposition_(phase_transition)]
is_a: ENVO:01001510 ! material congelation process

[Term]
id: ENVO:01000739
name: habitat
def: "An environmental system which can sustain and allow the growth of an ecological population." [EnvO:EnvO]
comment: A habitat's specificity to an ecological population differentiates it from other environment classes.
xref: EcoLexicon:habitat
xref: https://en.wikipedia.org/wiki/Habitat
xref: LTER:238
xref: SWEETRealm:Habitat
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01001110 ! ecosystem
relationship: BFO:0000050 ENVO:01000817 ! part of biosphere

[Term]
id: ENVO:01000741
name: recycling process
def: "A process during which materials deemed as waste are separated and converted into a form which can be used as input by the same processes which generated them." [https://stats.oecd.org/glossary/detail.asp?ID=2260]
comment: This has been created for SDGIO. Revision is likely, but the general meaning should be stable. The frame of reference for determining what is 'waste' and what is a  'resource' is unclear.
synonym: "proceso de reciclaje" EXACT []
synonym: "processo di riciclo" EXACT []
synonym: "Recycling-Prozess" EXACT []
synonym: "資源回收" EXACT []
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:01000742
name: carbon-bearing gas emission process
def: "A carbon emission process is any environmental process which outputs a carbon-bearing gas." []
comment: Requested for SDGIO. Likely to be revised.
is_a: ENVO:03000093 ! hydrocarbon gas emission process

[Term]
id: ENVO:01000743
name: land consumption process
def: "A process in which natural ecosystems present over an expanse of land are removed and replaced with anthropogenic ecosystems." [Adapted from EEA (1997) The concept of environmental space\, Copenhagen\, URL: http\://www.eea.europa.eu/publications/92-9167-078-2/at_download/file]
comment: These anthropogenic ecosystems may include urban or other built-up settlements or anthropogenic ecosystems used for activities such as forestry or agriculture.
is_a: ENVO:01000952 ! anthropisation
relationship: RO:0000057 ENVO:01000635 ! has participant planetary landmass

[Term]
id: ENVO:01000752
name: area of barren land
def: "An area of a planet's surface which is primarily composed of bedrock, desert pavement, scarp rock, talus, material exposed by slides, volcanic material, glacial debris, sand, material exposed during strip mining, gravel, and other accumulations of earthen material in contact with an atmospheric column extending from the planetary boundary layer to the planet's exosphere with little to no physical obstruction." [https://en.wikipedia.org/wiki/Exosphere, https://en.wikipedia.org/wiki/Planetary_surface, https://www.mrlc.gov/nlcd11_leg.php]
comment: According to the NLCD 2011, areas of barren land generally have less than 15% cover of vegetation. A specific threshold is not asserted in this definition.
xref: NLCD:31
is_a: ENVO:01001199 ! terrestrial environmental zone
relationship: RO:0002220 ENVO:01000323 ! adjacent to atmospheric boundary layer

[Term]
id: ENVO:01000755
name: aeroform
def: "A part of an astronomical body which is primarily composed of a continuous volume of gaseous or aerosolised material held in shape by one or more environmental processes." []
comment: Similar, in spirit, to landform. This class may need to be split into aerosols and 'pure' volumes of gas.
is_a: ENVO:01001478 ! gaseous astronomical body part
relationship: RO:0001025 ENVO:01000267 ! located in atmosphere

[Term]
id: ENVO:01000760
name: cloud
def: "A cloud is a visible mass of aerosolised liquid droplets or frozen crystals suspended in an atmosphere above the surface of a planetary body." [https://cloudatlas.wmo.int/introduction-and-principles-of-cloud-classification.html, https://en.wikipedia.org/wiki/Cloud]
comment: On Earth clouds are formed by the saturation of air in the homosphere when air cools or gains water vapor. Please use the "water-based cloud" class and its subclasses for Earth's clouds. Note that this class describes clouds as countable objects, rather than 'cloud material'. It also refers only to clouds made up of a water-based material.
synonym: "cloud mass" EXACT []
is_a: ENVO:01001008 ! meteor

[Term]
id: ENVO:01000769
name: carbon dioxide emission process
def: "A carbon emission process is any environmental process which releases carbon dioxide gas into the atmosphere." []
comment: Requested for SDGIO. This class may be revised in future once the offical definitions become more clear.
is_a: ENVO:01000742 ! carbon-bearing gas emission process

[Term]
id: ENVO:01000773
name: village
def: "A village is a clustered human settlement or community, larger than a hamlet but smaller than a town, with a population ranging from a few hundred to a few thousand. Though often located in rural areas, the term urban village is also applied to certain urban neighbourhoods. Villages are normally permanent, with fixed dwellings; however, transient villages can occur. Further, the dwellings of a village are fairly close to one another, not scattered broadly over the landscape, as a dispersed settlement." [https://en.wikipedia.org/wiki/Village]
is_a: ENVO:01001829 ! human settlement

[Term]
id: ENVO:01000776
name: piece of plastic
def: "A mass of solid material which is primarily composed of plastic." []
synonym: "pedazo de plástico" EXACT []
synonym: "pezzo di plastica" EXACT []
synonym: "Plastikstück" EXACT []
is_a: ENVO:01001687 ! mass of solid material
intersection_of: ENVO:01001687 ! mass of solid material
intersection_of: RO:0002473 ENVO:06105112 ! composed primarily of synthetic plastic
relationship: RO:0002473 ENVO:06105112 ! composed primarily of synthetic plastic

[Term]
id: ENVO:01000785
name: material extraction process
def: "A planned process during which a portion of environmental material is removed from a material entity." []
comment: Created for SDGIO and intended to be a more general form of resource extraction process.
is_a: BFO:0000003 ! occurrent
relationship: BFO:0000051 ENVO:03000010 ! has part material transport process
relationship: RO:0000057 ENVO:00010483 ! has participant environmental material

[Term]
id: ENVO:01000786
name: fire
def: "A fire is a process whereby rapid and exothermic oxidation of a material through a combustion process releases heat, light, and other products." [http://www.eionet.europa.eu/gemet/en/concept/3212, https://en.wikipedia.org/wiki/Fire]
comment: Not to be confused with a flame - the visible portion of gas released by a fire . Oxidation processes such as rusting or biological digestion are not subsumed here.
is_a: ENVO:01000839 ! combustion process

[Term]
id: ENVO:01000792
name: mass gaseous flow
def: "A process whereby a large volume of gas moves due to a disequilibrium of physical forces." [https://en.wikipedia.org/wiki/Wind]
comment: This class refers to all forms of "wind": from the familiar movement of air in the Earth's atmosphere to the solar wind. Use a subclass to be more precise.
is_a: ENVO:01001747 ! mass fluid flow
relationship: RO:0000057 ENVO:01000797 ! has participant gaseous environmental material

[Term]
id: ENVO:01000793
name: atmospheric wind
is_a: ENVO:01000792 ! mass gaseous flow
is_a: ENVO:02500003 ! atmospheric process

[Term]
id: ENVO:01000797
name: gaseous environmental material
def: "A material entity which is composed of one or more chemical entities and has neither independent shape nor volume but tends to expand indefinitely." [http://www.merriam-webster.com/dictionary/gas]
is_a: ENVO:02000140 ! fluid environmental material
intersection_of: ENVO:00010483 ! environmental material
intersection_of: RO:0000086 PATO:0001547 ! has quality quality of a gas
relationship: RO:0000086 PATO:0001547 ! has quality quality of a gas

[Term]
id: ENVO:01000798
name: plasma
def: "A material entity which is composed of a volume of unbound positive and negative particles in roughly equal numbers, conducts electricity, and possesses internal magnetic fields." [http://www.merriam-webster.com/dictionary/plasma, https://en.wikipedia.org/wiki/Plasma_%28physics%29]
is_a: ENVO:02000140 ! fluid environmental material

[Term]
id: ENVO:01000799
name: astronomical body
def: "An object which is naturally occuring, bound together by gravitational or electromagnetic forces, and surrounded by space." [https://en.wikipedia.org/wiki/Astronomical_object]
comment: Astronomical bodies are usually cohesive, thus the use of the term 'object' sensu BFO 'object'.
is_a: ENVO:01000804 ! astronomical object

[Term]
id: ENVO:01000800
name: planet
def: "A planet is an astronomical body orbiting a star or stellar remnant that is massive enough to be rounded by its own gravity, is not massive enough to cause thermonuclear fusion, and has cleared its neighbouring region of planetesimals." [http://solarsystem.nasa.gov/planets/whatisaplanet, https://en.wikipedia.org/wiki/Planet]
comment: Considerable debate on the definition of planet exists.
is_a: ENVO:01000799 ! astronomical body

[Term]
id: ENVO:01000801
name: star
def: "An astronomical object which is composed primarily of luminous plasma held in a spherical form by gravitational forces." [https://en.wikipedia.org/wiki/Star]
is_a: ENVO:01000799 ! astronomical body
is_a: ENVO:01001686 ! mass of environmental material
relationship: RO:0002473 ENVO:01000798 ! composed primarily of plasma

[Term]
id: ENVO:01000804
name: astronomical object
def: "An object which is composed of one or more gravitationally bound structures that are associated with a position in space." [https://en.wikipedia.org/wiki/Astronomical_object]
comment: If there is only one astronomical body involved, this class is equivalent to ENVO:01000799. This may be problematic with reasoning, but it seems to be true to the rather fuzzy definitions found thus far.
is_a: BFO:0000030 ! object
relationship: BFO:0000051 ENVO:01000799 ! has part astronomical body
relationship: RO:0000086 ENVO:01001164 ! has quality geodiversity
relationship: RO:0002219 ENVO:01000637 ! surrounded by outer space

[Term]
id: ENVO:01000813
name: astronomical body part
def: "A material part of an astronomical body." []
comment: Material parts of astronomical bodies generally have boundaries formed by discontinuities in qualities, composition, or other physical characterisitcs. These boundaries are sometimes sharp, and sometimes diffuse, with different classification systems and communities declaring varying thresholds (e.g. for where a shoreline, forest, or other entity begins and ends). However, some boundaries are declared by fiat - that is, by arbitrary human convention or decree - particularly by regulatory or other authorities and communities of practice. The classes in this hierarchy attempt to offer generalisable definitions that allow multiple classfiication systems to map to and interoperate through. If desired, we can create classes that declare thresholds used by a given authority or community under the more generic ones, annotated with source information.
is_a: BFO:0000040 ! material entity
intersection_of: BFO:0000040 ! material entity
intersection_of: BFO:0000050 ENVO:01000799 ! part of astronomical body
relationship: BFO:0000050 ENVO:01000799 ! part of astronomical body

[Term]
id: ENVO:01000814
name: solid environmental material
def: "An environmental material which is in a solid state." []
comment: This is a defined class: its subclasses will not be asserted, but filled by inference.
is_a: ENVO:00010483 ! environmental material
intersection_of: ENVO:00010483 ! environmental material
intersection_of: RO:0000086 PATO:0001546 ! has quality quality of a solid
relationship: RO:0000086 PATO:0001546 ! has quality quality of a solid

[Term]
id: ENVO:01000815
name: liquid environmental material
def: "An environmental material which is in a liquid state." []
comment: This is a defined class: most of its subclasses will not be asserted, but filled by inference.
is_a: ENVO:02000140 ! fluid environmental material
intersection_of: ENVO:00010483 ! environmental material
intersection_of: RO:0000086 PATO:0001548 ! has quality quality of a liquid
relationship: RO:0000086 PATO:0001548 ! has quality quality of a liquid

[Term]
id: ENVO:01000817
name: biosphere
def: "An astronomical body part which includes all the living entities within the gravitational sphere of influence of that body, as well as the non-living and dead entities with which they interact." [http://www.biology-online.org/dictionary/Biosphere, https://en.wikipedia.org/wiki/Biosphere]
comment: The gravitational sphere of influence referenced in this class' definition is the Hill sphere: a region in which an object dominates the attraction of satellites despite gravitational perturbations.
is_a: ENVO:01000813 ! astronomical body part

[Term]
id: ENVO:01000819
name: hydrosphere
def: "An astronomical body part which is composed of the combined mass of water found on, under, and over the surface of a planet." [https://en.wikipedia.org/wiki/Hydrosphere]
comment: This is a very broad and, in practice, poorly defined term. Please consider using or requesting a more specific class.
is_a: ENVO:01001477 ! liquid astronomical body part
relationship: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01000820
name: pedosphere
def: "An astronomical body part which is composed of soil, subject to soil formation processes, and found on the surface of a lithosphere." [https://en.wikipedia.org/wiki/Pedosphere]
comment: This is a very broad and, in practice, poorly defined term. Please consider using or requesting a more specific class.
is_a: ENVO:01000813 ! astronomical body part
relationship: RO:0002131 ENVO:01000267 ! overlaps atmosphere
relationship: RO:0002131 ENVO:01000646 ! overlaps lithosphere
relationship: RO:0002131 ENVO:01000817 ! overlaps biosphere
relationship: RO:0002131 ENVO:01000819 ! overlaps hydrosphere
relationship: RO:0002473 ENVO:00001998 ! composed primarily of soil

[Term]
id: ENVO:01000828
name: humid air
def: "Air which has increased levels of water vapour." []
is_a: ENVO:00002005 ! air
relationship: ENVO:02000200 ENVO:01000266 ! has increased levels of water vapour
relationship: RO:0000086 PATO:0015010 ! has quality increased humidity

[Term]
id: ENVO:01000829
name: water vapour saturated air
def: "Air which has a partial pressure of water vapour equal or near equal to its equilibrium vapor pressure at a given temperature." []
comment: "Near equal" is meant to reflect that there will be fluctuations around the equilibrium point.
synonym: "water-vapour-saturated air" EXACT []
is_a: ENVO:01000828 ! humid air

[Term]
id: ENVO:01000830
name: water-based rainfall
def: "A hydrological precipitation process in which atmospheric water vapour condenses to form droplets of liquid water massive enough to fall to a planetary surface due to the planet's gravity." [https://en.wikipedia.org/wiki/Rain]
comment: This is the process which typically happens on Earth. Other planets may have different liquids involved in the process.
is_a: ENVO:01000703 ! hydrological precipitation process
relationship: RO:0000057 ENVO:01000829 ! has participant water vapour saturated air
relationship: RO:0000057 ENVO:01000832 ! has participant raindrop

[Term]
id: ENVO:01000831
name: droplet
def: "A droplet is a small column of liquid, bounded completely or almost completely by free surfaces which maintains its shape due to the surface tension of the liquid." [https://en.wikipedia.org/wiki/Drop_%28liquid%29]
comment: No attempt is made to differentiate between drops and droplets. This may be added, if requested.
is_a: ENVO:01001690 ! mass of liquid

[Term]
id: ENVO:01000832
name: raindrop
def: "A droplet formed by condensation of vapour in an atmosphere and which is sufficiently massive to overcome atmospheric resistance and fall to a planetary surface due to gravity." []
is_a: ENVO:01000831 ! droplet
relationship: RO:0002354 ENVO:01000724 ! formed as result of condensation process

[Term]
id: ENVO:01000833
name: water droplet
def: "A droplet of water" []
is_a: ENVO:01000831 ! droplet
intersection_of: ENVO:01000831 ! droplet
intersection_of: RO:0002473 ENVO:00002006 ! composed primarily of liquid water
relationship: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01000834
name: water raindrop
comment: This is the class intended for use when describing raindrops on Earth. These typically have a diamter of  0.1 to 9 millimetres.
is_a: ENVO:01000832 ! raindrop
is_a: ENVO:01000833 ! water droplet

[Term]
id: ENVO:01000835
name: cloud droplet
def: "A droplet which is spherical in shape and suspended in an atmosphere, being of too small a mass to be pulled to a planetary surface by gravity." [https://en.wikipedia.org/wiki/Rain]
is_a: ENVO:01000831 ! droplet

[Term]
id: ENVO:01000836
name: water-based cloud droplet
def: "A cloud droplet composed primarily of water." []
synonym: "water based cloud droplet" EXACT []
is_a: ENVO:01000833 ! water droplet
is_a: ENVO:01000835 ! cloud droplet
intersection_of: ENVO:01000835 ! cloud droplet
intersection_of: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01000838
name: smoke
comment: Smoke is a collection of airborne solid and liquid particulates and gases emitted when a material undergoes combustion or pyrolysis, together with the quantity of gas that is entrained or otherwise mixed into the mass {xref="https://en.wikipedia.org/wiki/Smoke"}
is_a: ENVO:00010505 ! aerosol
relationship: RO:0002354 ENVO:01000839 ! formed as result of combustion process

[Term]
id: ENVO:01000839
name: combustion process
def: "Combustion or burning is a high-temperature exothermic redox chemical reaction between a fuel and an oxidant that produces oxidized, often gaseous products, in a mixture termed as smoke." [https://en.wikipedia.org/wiki/Combustion]
comment: Unlike the "combustion" class in the Chemical Methods Ontology, this class is not necessarily a planned process. http://purl.obolibrary.org/obo/CHMO_0001473
is_a: ENVO:01000840 ! thermolysis
is_a: ENVO:01001654 ! aerosol formation process
relationship: RO:0002234 ENVO:01000838 ! has output smoke

[Term]
id: ENVO:01000840
name: thermolysis
def: "A chemical decomposition (the separation of a single chemical compound into its two or more elemental parts or to simpler compounds) caused by heat." []
synonym: "thermal decomposition" EXACT []
is_a: ENVO:03000043 ! material transformation process

[Term]
id: ENVO:01000841
name: pyrolysis
def: "A thermolysis process in which organic material is decomposed in the absence of oxygen." []
is_a: ENVO:01000840 ! thermolysis
is_a: ENVO:01001654 ! aerosol formation process
relationship: RO:0000057 ENVO:01000155 ! has participant organic material
relationship: RO:0002234 ENVO:01000838 ! has output smoke

[Term]
id: ENVO:01000842
name: smog
def: "A fog which is intermixed with smoke or other combustion products and their derivatives." []
is_a: ENVO:01000844 ! fog
relationship: RO:0000087 CHEBI:78298 ! has role environmental contaminant

[Term]
id: ENVO:01000844
name: fog
def: "A visible mass of cloud water droplets or ice crystals suspended in the air at or near the surface of an astronomical body." [https://en.wikipedia.org/wiki/Fog]
comment: Fog is more opaque than mist, reducing visibility to under one kilometre. This class refers only to fog formed by materials primarily composed of water. "Fog can be considered a type of low-lying cloud and is heavily influenced by nearby bodies of water, topography, and wind conditions. In turn, fog has affected many human activities, such as shipping, travel, and warfare." https://en.wikipedia.org/wiki/Fog
xref: http://sweetontology.net/phenAtmoFog/Fog
is_a: ENVO:01001088 ! aerosolised liquids
is_a: ENVO:01001652 ! atmospheric aerosol
relationship: RO:0001025 ENVO:01000267 ! located in atmosphere
relationship: RO:0002353 ENVO:01000724 ! output of condensation process
relationship: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01000845
name: crystal
def: "A solid material whose constituents, such as atoms, molecules or ions, are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions." [https://en.wikipedia.org/wiki/Crystal]
comment: This class refers to a portion of crystal and not an individual crystal.
is_a: ENVO:01000814 ! solid environmental material
relationship: RO:0000086 PATO:0001411 ! has quality structured

[Term]
id: ENVO:01000846
name: water ice crystal
def: "A crystal which is primarily composed of water ice." []
comment: Any one of a number of macroscopic, crystalline forms in which ice appears, including hexagonal columns, hexagonal platelets, dendritic crystals, ice needles, and combinations of these forms.  The crystal lattice of ice is hexagonal in its symmetry under most atmospheric conditions. {xref="https://orcid.org/0000-0003-4808-4736"}
xref: http://sweetontology.net/matrWater/Ice
is_a: ENVO:01000845 ! crystal
relationship: RO:0002473 ENVO:01000277 ! composed primarily of water ice

[Term]
id: ENVO:01000869
name: area of scrub
def: "An area of a planet's surface which is primarily covered by a shrubs, young trees, or stunted trees.. The surfaces of this area are in contact with an atmospheric column extending from the planetary boundary layer to the planet's exosphere with little to no physical obstruction." [http://dx.doi.org/10.1016/j.rse.2015.07.014, https://en.wikipedia.org/wiki/Exosphere, https://en.wikipedia.org/wiki/Planetary_surface, https://en.wikipedia.org/wiki/Subshrub, https://www.mrlc.gov/nlcd11_leg.php]
comment: According to the NLCD 2011, areas of scrub or shrub are dominated by shrubs; less than 5 meters tall with shrub canopy typically greater than 20% of total vegetation. This class includes true shrubs, young trees in an early successional stage or trees stunted from environmental conditions. Such thresholds - which are themselves fuzzy - are not asserted in this definition.
synonym: "area of shrub" EXACT []
xref: NLCD:52
is_a: ENVO:01001293 ! bush area
relationship: BFO:0000050 ENVO:00000300 ! part of scrubland area
relationship: RO:0002220 ENVO:01000323 ! adjacent to atmospheric boundary layer

[Term]
id: ENVO:01000875
name: precipitation process
def: "A precipitation process is a process in which a portion of some substance segregates from a material in which that substance or its precursors were dissolved or suspended in and settles due to a force such as gravity or centrifugal force." [https://en.wikipedia.org/wiki/Precipitation_%28chemistry%29] {comment="https://en.wikipedia.org/wiki/Precipitation"}
is_a: ENVO:03000010 ! material transport process

[Term]
id: ENVO:01000876
name: storm
def: "A storm is an environmental process in which an environmental system and the processes it participates in are strongly perturbed by external forcings. These forcings typically increase the rates of processes unfolding in the system, relative to their normal rates." []
comment: The threshold of what constitutes "strong" perturbation is not defined here due to considerable semantic variation. If a specific threshold is required, please request a new term.
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:01000877
name: atmospheric storm
def: "An atmospheric storm is a process in which a portion of an astronomical body's atmosphere is strongly perturbed from its prevaling weather." [https://en.wikipedia.org/wiki/Storm]
is_a: ENVO:01000876 ! storm
is_a: ENVO:02500003 ! atmospheric process

[Term]
id: ENVO:01000878
name: thunderstorm
def: "An atmospheric storm which occurs in cumulonimbus clouds and during which lightning and thunder occur." []
comment: Thunderstorms may or may not involve processes which result in strong winds, heavy rain, snow, sleet, hail, or other forms of precipitation.
synonym: "electrical storm" EXACT []
synonym: "lightning storm" EXACT []
is_a: ENVO:01001294 ! convective storm
relationship: BFO:0000051 ENVO:01000898 ! has part atmospheric lightning

[Term]
id: ENVO:01000882
name: icestorm
def: "An atmospheric storm during which freezing rain falls and accumulates as ice on exposed surfaces." [https://en.wikipedia.org/wiki/Ice_storm, https://orcid.org/0000-0003-4808-4736]
comment: The U.S. National Weather Service defines an ice storm as a storm which results in the accumulation of at least 0.25-inch (6.4 mm) of ice on exposed surfaces. {xref="https://en.wikipedia.org/wiki/Ice_storm", xref="Hauer RJ, Dawson JO, Werner LP (2006) Trees and Ice Storms - The Development of Ice Storm-Resistant Urban Tree Populations (2 ed.). College of Natural Resources, University of Wisconsin–Stevens Point, and the Department of Natural Resources and Environmental Sciences and the Office of Continuing Education, University of Illinois at Urbana-Champaign. http://web.extension.uiuc.edu/forestry/publications/pdf/urban_community_forestry/trees_and_ice_storms_2006.pdf"}
synonym: "glaze event" EXACT []
synonym: "glaze storm" EXACT []
synonym: "ice storm" EXACT []
synonym: "silver storm" EXACT []
synonym: "silver thaw" EXACT []
xref: http://sweetontology.net/phenAtmoPrecipitation/IceStorm
is_a: ENVO:01000877 ! atmospheric storm
relationship: BFO:0000051 ENVO:01000896 ! has part freezing rainfall
relationship: RO:0002234 ENVO:01000547 ! has output glaze ice layer

[Term]
id: ENVO:01000883
name: area of developed open space
def: "An area of a planet's surface which is primarily covered by cultivated or anthropically maintained vegetation planted for recreation, erosion control, or aesthetic purposes interspersed by constructed or manufactured objects and materials. This area is in contact with an atmospheric column extending from the planetary boundary layer to the planet's exosphere with little to no physical obstruction." [https://en.wikipedia.org/wiki/Exosphere, https://en.wikipedia.org/wiki/Planetary_surface, https://www.mrlc.gov/nlcd11_leg.php]
comment: According to the NLCD 2011, areas of developed open space are dominated by vegetation such as lawn grasses and include large-lot single-family housing units, parks, golf courses. Further, it is asserted that "impervious surfaces", most likely referring to concrete and related substances, cover less than 20% of the area. Such thresholds - which are themselves fuzzy - are not asserted in this definition.
xref: NLCD:21
is_a: ENVO:01001200 ! anthropised terrestrial environmental zone
relationship: BFO:0000050 ENVO:01000248 ! part of dense settlement biome
relationship: RO:0002220 ENVO:01000323 ! adjacent to atmospheric boundary layer

[Term]
id: ENVO:01000887
name: area of sedge- and forb-dominated herbaceous vegetation
def: "An area of a planet's surface which is primarily covered by sedges or forbs, possibly interpersed with grasses or grass-like plants. This area is in contact with an atmospheric column extending from the planetary boundary layer to the planet's exosphere with little to no physical obstruction." [https://en.wikipedia.org/wiki/Exosphere, https://en.wikipedia.org/wiki/Planetary_surface, https://www.mrlc.gov/nlcd11_leg.php]
comment: According to the NLCD 2011, at least 80% of these areas are covered by sedge or forbs.  Such thresholds - which are themselves fuzzy - are not strictly asserted in this definition. The NLCD description also notes that land covered by sedge tundra and sedge tussock tundra are subsumed in this category. The original definition notes that this is intended as an "Alaska only" category.
xref: NLCD:72
is_a: ENVO:01001305 ! vegetated area
relationship: RO:0002220 ENVO:01000323 ! adjacent to atmospheric boundary layer

[Term]
id: ENVO:01000888
name: area of gramanoid or herbaceous vegetation
def: "An area of a planet's surface which is primarily covered by gramanoid or herbaceous vegetation and which is not subject to intensive management by humans. This area is in contact with an atmospheric column extending from the planetary boundary layer to the planet's exosphere with little to no physical obstruction." [https://en.wikipedia.org/wiki/Exosphere, https://en.wikipedia.org/wiki/Planetary_surface, https://www.mrlc.gov/nlcd11_leg.php]
comment: According to the NLCD 2011, at least 80% of these areas are covered by grasslands or non-woody, herbaceous plants.  Such thresholds - which are themselves fuzzy - are not strictly asserted in this definition. The NLCD description also notes that, while no "intensive" management such as tilling is performed in these areas, they may be used for grazing.
xref: NLCD:71
is_a: ENVO:00000106 ! grassland area
relationship: RO:0002220 ENVO:01000323 ! adjacent to atmospheric boundary layer

[Term]
id: ENVO:01000895
name: snowfall
def: "A hydrological process in which irregular aggregates of snow fall to the surface of an astronomical body." []
synonym: "snow fall" EXACT []
xref: http://sweetontology.net/phenAtmoPrecipitation/Snowfall
is_a: ENVO:01000703 ! hydrological precipitation process
relationship: RO:0000057 ENVO:01000406 ! has participant snow

[Term]
id: ENVO:01000896
name: freezing rainfall
def: "Water-based rainfall which freezes either 1) on impact with a surface to form a coating of clear ice (glaze) or 2) after percolating through surface layers." [https://orcid.org/0000-0003-4808-4736]
comment: A surface temperature inversion is usually required. In such an inversion, the surface must have a temperature below freezing, while the temperature of the atmosphere where the precipitation forms is above freezing. Alternately, if the temperature of the ground surface and glazed objects is typically near or below freezing (0C or 32F), it is necessary that the water drops be supercooled before striking. Freezing rain can sometimes occur on surfaces exposed to the air (such as tree limbs) with air temperatures slightly above freezing in strong winds. Local evaporational cooling may result in freezing. Freezing rain frequently occurs, therefore, as a transient condition between the occurrence of rain and ice pellets (sleet). When encountered by an aircraft in flight, freezing rain can cause a dangerous accretion of clear icing. In aviation weather observations, this hydrometeor is encoded ZR by NOAA. {xref="https://orcid.org/0000-0003-4808-4736"}
xref: http://sweetontology.net/phenAtmoPrecipitation/FreezingRain
xref: METAR:FZRA
is_a: ENVO:01000830 ! water-based rainfall

[Term]
id: ENVO:01000897
name: electrostatic discharge process
def: "A process during which a sudden flow of electricity occurs, often accompanied by a visible release of photons, between two electrically charged objects due to contact, an electrical short, or dielectric breakdown." [https://en.wikipedia.org/wiki/Electrostatic_discharge]
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:01000898
name: atmospheric lightning
def: "A sudden electrostatic discharge which occurs during an electrical storm as differentially charged atmospheric entities equalise their charge." [https://en.wikipedia.org/wiki/Lightning]
synonym: "lightning" EXACT []
is_a: ENVO:01000897 ! electrostatic discharge process
is_a: ENVO:02500003 ! atmospheric process
relationship: RO:0000057 ENVO:01000760 ! has participant cloud
relationship: RO:0002234 ENVO:01000798 ! has output plasma

[Term]
id: ENVO:01000923
name: petting zoo
def: "A petting zoo is a zoological garden which contains domesticated non-human animals and some wild non-human animals that are docile enough for humans to touch and feed." [https://en.wikipedia.org/wiki/Petting_zoo]
comment: Petting zoos are often nested within a zoological garden featuring wild non-human animals, not docile enough for humans to touch.
synonym: "petting farm" EXACT []
is_a: ENVO:00010625 ! zoological garden

[Term]
id: ENVO:01000925
name: abattoir
def: "A facility in which non-human animals are slaughtered and processed for human consumption." [https://en.wikipedia.org/wiki/Slaughterhouse]
synonym: "slaughter plant" EXACT []
synonym: "slaughterhouse" EXACT []
is_a: ENVO:00003861 ! industrial building

[Term]
id: ENVO:01000927
name: day care building
def: "A building which is used to care for a human child during the working day by a person, outside the child's immediate family, other than that child's legal guardians." [https://en.wikipedia.org/wiki/Day_care]
comment: This is a kind of day care facility. A facility need not be a building.
synonym: "child care building" EXACT []
synonym: "daycare building" EXACT []
is_a: ENVO:01001222 ! commercial building

[Term]
id: ENVO:01000934
name: restaurant
def: "A building within which food and drink are prepared and served to customers in exchange for money or other goods and/or services." [https://en.wikipedia.org/wiki/Restaurant]
synonym: "eatery" EXACT []
is_a: ENVO:01001222 ! commercial building

[Term]
id: ENVO:01000935
name: campground
def: "A part of an ecosystem which may be or has been used for one or more overnight stays by humans sheltering in tents, camper vans, caravans, or improvised shelters." [https://en.wikipedia.org/wiki/Campsite]
synonym: "camping ground" EXACT []
synonym: "camping pitch" EXACT []
synonym: "camping site" EXACT []
synonym: "campsite" EXACT []
is_a: ENVO:00000002 ! anthropogenic geographic feature

[Term]
id: ENVO:01000941
name: planetary subsurface zone
def: "Regions of a planet which are not exposed to the planet's atmosphere or space, often comprising parts of one or more planetary structural layers." []
is_a: ENVO:01001776 ! subsurface zone of an astronomical body
relationship: RO:0002131 ENVO:01000639 ! overlaps planetary structural layer
relationship: RO:0002220 ENVO:01000324 ! adjacent to planetary surface

[Term]
id: ENVO:01000944
name: microplastic particle
def: "A piece of plastic which has a diameter less than five millimetres." [https://en.wikipedia.org/wiki/Microplastics, https://marinedebris.noaa.gov/file/2192/download?token=5dvqb-YY]
comment: This classification is based on the thresholds detailed in GESAMP report # 99 on recommendation from the SDG 14 indicator team. While the definition is in accordance with the common use of this term (as per GESAMP report # 99), alternative size classifications exist. Alternative classifications are a piece of plastic which is between 1 and 5 millimetres in diameter, a piece of plastic which has a diameter less than 1 millimetre, or a piece of plastic which has a diameter greater than 330 micrometres. The use of the word diameter in this case was understood to mean the generalised form of diameter, i.e. the largest distance between two points belonging to an object. {xref="http://www.gesamp.org/publications/guidelines-for-the-monitoring-and-assessment-of-plastic-litter-in-the-ocean"}
is_a: ENVO:01000776 ! piece of plastic

[Term]
id: ENVO:01000946
name: secondary microplastic particle
def: "A microplastic particle which is derived from the breakdown of larger plastic debris." [https://en.wikipedia.org/wiki/Microplastics, https://marinedebris.noaa.gov/file/2192/download?token=5dvqb-YY]
comment: The debris that make up the Great Pacific Garbage Patch constantly release microplastics as they break down.
synonym: "microplastica secondaria" EXACT []
synonym: "microplástico secundario" EXACT []
synonym: "Sekundäres Mikroplastik" EXACT []
is_a: ENVO:01000944 ! microplastic particle

[Term]
id: ENVO:01000951
name: natural environment
def: "An environmental system in which minimal to no anthropisation has occurred and non-human agents are the primary determinants of the system's dynamics and composition." [https://en.wikipedia.org/wiki/Anthropization, https://en.wikipedia.org/wiki/Natural_environment]
comment: In most contexts, 'natural' is defined by the lack of intervention or influence by humans and their activities. On Earth, most environments fall on a scale between completely natural and anthropised.
is_a: ENVO:01000254 ! environmental system

[Term]
id: ENVO:01000952
name: anthropisation
def: "A process during which a natural environmental system is altered by human action." [https://en.wikipedia.org/wiki/Anthropization]
comment: An area may be classified as anthropized even though it looks natural, such as grasslands that have been deforested by humans. It can be difficult to determine how much a site has been anthropized in the case of urbanization because one must be able to estimate the state of the landscape before significant human action. {xref="https://en.wikipedia.org/wiki/Anthropization"}
synonym: "anthropization" EXACT []
is_a: ENVO:01001434 ! anthropogenic ecosystem conversion process
intersection_of: ENVO:01001434 ! anthropogenic ecosystem conversion process
intersection_of: RO:0002233 ENVO:01000951 ! has input natural environment
intersection_of: RO:0002234 ENVO:01000313 ! has output anthropogenic environment
relationship: RO:0002233 ENVO:01000951 ! has input natural environment
relationship: RO:0002234 ENVO:01000313 ! has output anthropogenic environment

[Term]
id: ENVO:01000958
name: terrestrial planet
def: "A planet that is composed primarily of silicate rocks or metals." [https://en.wikipedia.org/wiki/Terrestrial_planet]
synonym: "rocky planet" EXACT []
synonym: "telluric planet" EXACT []
is_a: ENVO:01000800 ! planet

[Term]
id: ENVO:01000965
name: constructed swimming pool
def: "A construction which is designed to hold water in which humans may swim or perform other leisure activities." [https://en.wikipedia.org/wiki/Swimming_pool]
synonym: "paddling pool" EXACT []
synonym: "swimming bath" EXACT []
synonym: "swimming pool" EXACT []
synonym: "wading pool" EXACT []
is_a: ENVO:00000070 ! human construction

[Term]
id: ENVO:01000967
name: public swimming pool
def: "A constructed swimming pool which is owned by a governmental or state entity." [https://en.wikipedia.org/wiki/Private_ownership, https://en.wikipedia.org/wiki/Swimming_pool]
is_a: ENVO:01000965 ! constructed swimming pool

[Term]
id: ENVO:01000981
name: mass liquid flow
def: "A process whereby a volume of liquid moves due to a disequilibrium of physical forces." [https://en.wikipedia.org/wiki/Wind]
comment: This class can refer to the flow of any material in a liquid phase.
is_a: ENVO:01001747 ! mass fluid flow
relationship: RO:0000057 ENVO:01000815 ! has participant liquid environmental material

[Term]
id: ENVO:01000982
name: water flow process
def: "A material transport process during which a volume of liquid water is transported due to a disequilibria in physical forces." []
is_a: ENVO:02500031 ! hydrological process
is_a: ENVO:03000010 ! material transport process
intersection_of: ENVO:03000010 ! material transport process
intersection_of: RO:0000057 ENVO:00002006 ! has participant liquid water
relationship: RO:0000057 ENVO:00002006 ! has participant liquid water

[Term]
id: ENVO:01000983
name: technosphere
def: "A part of an astronomical body which includes, as parts, all the entities which have been constructed or manufactured by humans or their technology and which are within the gravitational sphere of influence of that body." [http://dx.doi.org/10.1177/2053019616677743, http://www.yourdictionary.com/technosphere, https://www.sciencedaily.com/releases/2016/11/161130085021.htm]
comment: The gravitational sphere of influence referenced in this class' definition is the Hill sphere: a region in which an object dominates the attraction of satellites despite gravitational perturbations.
is_a: ENVO:01000813 ! astronomical body part
relationship: RO:0002131 ENVO:01000817 ! overlaps biosphere
relationship: RO:0002473 ENVO:00000070 ! composed primarily of human construction
relationship: RO:0002473 ENVO:00003074 ! composed primarily of manufactured product

[Term]
id: ENVO:01000993
name: manufacturing process
def: "A planned process during which raw or recycled materials are transformed into products for use or sale using labour and machines, tools, chemical and biological processing, or formulation." [https://en.wikipedia.org/wiki/Manufacturing]
comment: The term may refer to a range of human activity, from handicraft to high tech, but is most commonly applied to industrial production, in which raw materials are transformed into finished goods on a large scale. {xref="https://en.wikipedia.org/wiki/Manufacturing"}
is_a: BFO:0000003 ! occurrent
relationship: BFO:0000051 ENVO:01000952 ! has part anthropisation
relationship: RO:0002608 NCBITaxon:9606 ! process has causal agent Homo sapiens

[Term]
id: ENVO:01000994
name: planetary manufacturing process
def: "A manufacturing process which occurs on a planet." []
comment: See https://github.com/EnvironmentOntology/envo/issues/513 for discussion.
is_a: ENVO:01000993 ! manufacturing process
is_a: ENVO:02500027 ! anthropogenic environmental process
relationship: BFO:0000066 ENVO:01000800 ! occurs in planet
relationship: RO:0002232 ENVO:01000983 ! has end location technosphere

[Term]
id: ENVO:01000996
name: human-directed construction process
def: "An process during which natural or manufactured materials and products are processed and arranged by humans or their technology into structures." []
is_a: BFO:0000003 ! occurrent
relationship: BFO:0000051 ENVO:01000952 ! has part anthropisation
relationship: BFO:0000051 ENVO:03000010 ! has part material transport process
relationship: BFO:0000051 ENVO:03000043 ! has part material transformation process
relationship: RO:0002608 NCBITaxon:9606 ! process has causal agent Homo sapiens

[Term]
id: ENVO:01000997
name: environmental system determined by a quality
def: "An environmental system which is determined by materials bearing roughly homogeneous qualities." []
comment: Organisational class. Not intended for annotation.
is_a: ENVO:01000254 ! environmental system

[Term]
id: ENVO:01000998
name: environmental system determined by a material
def: "An environmental system within which an environmental material strongly influences the system's composition and properties." []
comment: Organisational class. Not intended for annotation. Subclasses describe environments which are usually permeated by an environmental material. They may also describe environments which are sufficiently close to a material, that their dynamics are strongly influenced by it (e.g. a patch of forest ecosystem neighbouring a uranium dump).
is_a: ENVO:01000254 ! environmental system
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 ENVO:00010483 ! determined by environmental material
relationship: RO:0002507 ENVO:00010483 ! determined by environmental material

[Term]
id: ENVO:01001000
name: environmental system determined by an organism
def: "An environmental system which is determined by a living organism." []
is_a: ENVO:01000254 ! environmental system
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 NCBITaxon:131567 ! determined by cellular organisms
relationship: RO:0002507 NCBITaxon:131567 ! determined by cellular organisms

[Term]
id: ENVO:01001001
name: plant-associated environment
def: "An environmental system determined by a green plant." []
synonym: "Viridiplantae-associated environment" EXACT []
is_a: ENVO:01001000 ! environmental system determined by an organism
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 NCBITaxon:33090 ! determined by Viridiplantae
relationship: RO:0002507 NCBITaxon:33090 ! determined by Viridiplantae

[Term]
id: ENVO:01001002
name: animal-associated environment
def: "An environmental system determined by an animal." []
synonym: "Metazoan-associated environment" EXACT []
is_a: ENVO:01001000 ! environmental system determined by an organism
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 NCBITaxon:33208 ! determined by Metazoa
relationship: RO:0002507 NCBITaxon:33208 ! determined by Metazoa

[Term]
id: ENVO:01001004
name: groundwater
def: "Underground water which is located in pore spaces found in rock or unconsolidated deposits such as soil, clay, or gravel." [https://en.wikipedia.org/wiki/Groundwater]
comment: The definition of aquifer is quite permissive, referencing any water bearing rock or unconsolidated material.
synonym: "ground water" EXACT []
is_a: ENVO:00005792 ! underground water
relationship: RO:0001025 ENVO:00012408 ! located in aquifer

[Term]
id: ENVO:01001008
name: meteor
def: "A meteor is any matter- or energy-based entity which is located in the atmosphere of an astronomical body." [https://cloudatlas.wmo.int/other-meteors.html]
is_a: BFO:0000030 ! object
intersection_of: BFO:0000030 ! object
intersection_of: RO:0001025 ENVO:01000267 ! located in atmosphere
relationship: RO:0001025 ENVO:01000267 ! located in atmosphere

[Term]
id: ENVO:01001010
name: hydrometeor
def: "A meteor which is primarily composed of water." [https://cloudatlas.wmo.int/other-meteors.html]
is_a: ENVO:01001008 ! meteor

[Term]
id: ENVO:01001012
name: lithometeor
def: "A meteor which is primarily composed of rock." []
is_a: ENVO:00000339 ! piece of rock
is_a: ENVO:01001008 ! meteor
intersection_of: ENVO:01001008 ! meteor
intersection_of: RO:0002473 ENVO:00001995 ! composed primarily of rock
relationship: RO:0001000 ENVO:01001068 ! derives from meteoroid

[Term]
id: ENVO:01001022
name: natural lake
def: "A lake which has formed as the result of processes that are not or are only minimally driven by human activity." []
is_a: ENVO:00000020 ! lake

[Term]
id: ENVO:01001023
name: radiation
def: "A process during which energy is emitted or transmitted in the form of waves or particles through space or a material medium." [https://en.wikipedia.org/wiki/Radiation]
is_a: ENVO:01001852 ! energy transfer process
relationship: RO:0000057 CHEBI:36342 ! has participant subatomic particle
relationship: RO:0000057 ENVO:00010483 ! has participant environmental material

[Term]
id: ENVO:01001024
name: particle radiation
def: "A radiation process during which energy is transmitted or emitted by means of fast-moving subatomic particles." [https://en.wikipedia.org/wiki/Particle_radiation]
is_a: ENVO:01001023 ! radiation

[Term]
id: ENVO:01001025
name: particle beam radiation
def: "A particle radiation process during which subatomic particles move in the same direction." [https://en.wikipedia.org/wiki/Particle_radiation]
is_a: ENVO:01001024 ! particle radiation

[Term]
id: ENVO:01001026
name: electromagnetic radiation
def: "A radiation process during which waves (or their quanta, photons) of the electromagnetic field propagate (radiate) through space carrying electromagnetic energy." [https://en.wikipedia.org/wiki/Electromagnetic_radiation]
comment: Note that this class is concerned only with active radiative processes: static electric and magnetic fields are not inlcuded. All electromagnetic radiation carries radiant energy.
synonym: "EM radiation" EXACT []
is_a: ENVO:01001023 ! radiation

[Term]
id: ENVO:01001027
name: acoustic radiation
def: "A radiation process during which mechanical waves generated by oscillations radiate through an environmental material." [https://en.wikipedia.org/wiki/Acoustics] {comment="https://en.wikipedia.org/wiki/Vibration", comment="https://en.wikipedia.org/wiki/Mechanical_wave"}
comment: The mechanical waves generated by this process are also referred to as pressure waves.
is_a: ENVO:01001023 ! radiation

[Term]
id: ENVO:01001029
name: fecal environment
def: "An environmental system which has its properties and dynamics determined by feces." []
is_a: ENVO:01000998 ! environmental system determined by a material
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 ENVO:00002003 ! determined by fecal material
relationship: RO:0002507 ENVO:00002003 ! determined by fecal material

[Term]
id: ENVO:01001030
name: environment determined by a metazoan secretion
def: "An environmental system which has its properties and dynamics determined by a bodily secretion of a metazoan." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:2100000 ! anatomical entity environment
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 UBERON:0000456 ! determined by secretion of exocrine gland
relationship: RO:0002507 UBERON:0000456 ! determined by secretion of exocrine gland

[Term]
id: ENVO:01001033
name: digestive tract environment
def: "An environmental system which has its properties and dynamics determined by a digestive tract." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:2100000 ! anatomical entity environment
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 UBERON:0001555 ! determined by digestive tract
relationship: RO:0002507 UBERON:0001555 ! determined by digestive tract

[Term]
id: ENVO:01001039
name: highly saline water
def: "Water which contains a highly increased concentration of dissolved salts, relative to their concentration in freshwater." []
comment: The United States Geological Survey classifies highly saline water as having around 10,000 to 35,000 ppm (1–3.5%) of dissolved salts.
synonym: "highly salty water" EXACT []
xref: EcoLexicon:saltwater
xref: https://en.wikipedia.org/wiki/Saline_water
xref: SWEETRealm:SalineWater
xref: SWEETRealm:SaltWater
is_a: ENVO:00002010 ! saline water

[Term]
id: ENVO:01001040
name: saline environment
def: "An environment which is determined by materials which bear significant concentrations of salts." []
comment: The thresholds for "significant" concentrations of salts vary widely and thus no committment is made in this class. Subclasses with more explicit thresholds can be made upon request.
is_a: ENVO:01000314 ! high osmolarity environment
is_a: ENVO:01000998 ! environmental system determined by a material

[Term]
id: ENVO:01001041
name: fungi-associated environment
def: "An environmental system determined by a fungal structure." []
synonym: "fungus-associated environment" EXACT []
is_a: ENVO:01001000 ! environmental system determined by an organism
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 NCBITaxon:4751 ! determined by Fungi
relationship: RO:0002507 NCBITaxon:4751 ! determined by Fungi

[Term]
id: ENVO:01001044
name: soil environment
def: "An environmental system which has its properties and dynamics determined by soil." []
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:01000998 ! environmental system determined by a material
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 ENVO:00001998 ! determined by soil
relationship: RO:0002507 ENVO:00001998 ! determined by soil

[Term]
id: ENVO:01001046
name: planetary subsurface environment
def: "An environmental system which has its properties and dynamics determined by the subsurface zone of a planet." []
is_a: ENVO:01000254 ! environmental system
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002131 ENVO:01000941 ! overlaps planetary subsurface zone
relationship: RO:0002131 ENVO:01000941 ! overlaps planetary subsurface zone

[Term]
id: ENVO:01001047
name: non-saline planetary subsurface environment
def: "An environmental system which has its properties and dynamics determined by those parts of a planetary subsurface zone which are not saline." []
is_a: ENVO:01001046 ! planetary subsurface environment

[Term]
id: ENVO:01001048
name: sediment environment
def: "An environmental system which has its properties and dynamics determined by sediment." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:01000998 ! environmental system determined by a material
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 ENVO:00002007 ! determined by sediment
relationship: RO:0002507 ENVO:00002007 ! determined by sediment

[Term]
id: ENVO:01001052
name: aerosol environment
def: "An environmental system which has its properties and dynamics determined by an aerosol." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:01000998 ! environmental system determined by a material
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002507 ENVO:00010505 ! determined by aerosol
relationship: RO:0002507 ENVO:00010505 ! determined by aerosol

[Term]
id: ENVO:01001053
name: saline aerosol environment
def: "An environmental system which has its properties and dynamics determined by a saline aerosol." []
is_a: ENVO:01001040 ! saline environment
is_a: ENVO:01001052 ! aerosol environment

[Term]
id: ENVO:01001054
name: non-saline aerosol environment
def: "An environmental system which has its properties and dynamics determined by an aerosol with a low concentration of dissolved solutes." []
is_a: ENVO:01001052 ! aerosol environment

[Term]
id: ENVO:01001055
name: environment associated with an animal part or small animal
def: "An environmental system determined by part of a living or dead animal, or a whole small animal." []
is_a: ENVO:01001110 ! ecosystem

[Term]
id: ENVO:01001068
name: meteoroid
def: "An astronomical body which is composed of rocky or metallic materials and is considerably smaller than asteroids." [https://en.wikipedia.org/wiki/Meteoroid]
is_a: ENVO:01000799 ! astronomical body
relationship: RO:0000086 PATO:0000587 ! has quality decreased size

[Term]
id: ENVO:01001069
name: metallic material
def: "A material which is composed primarily of one or more pure metals and which shows their properties." [] {comment="https://en.wikipedia.org/wiki/Metal"}
comment: While this class allows for some degree of contamination by non-metal substances, the material represented should show at least some of the typical features of a pure metal: hardness (except for liquid metals), opacity, lustre, malleability, fusibility, ductile  and good electrical and thermal conductivity.
is_a: ENVO:00010483 ! environmental material
relationship: RO:0000086 PATO:0000963 ! has quality opaque
relationship: RO:0000087 CHEBI:15022 ! has role electron donor
relationship: RO:0002473 CHEBI:33521 ! composed primarily of metal atom

[Term]
id: ENVO:01001078
name: weather
def: "Environmental variability which inheres in an astronomical body part or in outer space." [https://en.wikipedia.org/wiki/Space_weather, https://en.wikipedia.org/wiki/Weather]
comment: This class refers to all weather, including atmospheric and space weather. Please use a subclass for more specificity.
is_a: ENVO:01001081 ! environmental variability

[Term]
id: ENVO:01001081
name: environmental variability
def: "A condition which inheres in an environmental system by virtue of that system undergoing variation in its composition, the distribution of the qualities its components bear, and/or in the processes which occur within it and which it participates in." []
comment: This class is very general, but the nature of environmental variability is indeed quite variable. This class may be refined once we have more subclasses to consider.
is_a: ENVO:01000203 ! environmental condition

[Term]
id: ENVO:01001084
name: particulate matter formation process
def: "A process during which microscopic solid or liquid objects are formed." [https://en.wikipedia.org/wiki/Particulates]
is_a: ENVO:03000043 ! material transformation process
relationship: RO:0002234 ENVO:01000060 ! has output particulate environmental material

[Term]
id: ENVO:01001085
name: atmospheric aerosol formation
def: "An aerosol formation process which occurs in an atmosphere." [https://en.wikipedia.org/wiki/Particulates]
synonym: "atmospheric aerosol formation" EXACT []
is_a: ENVO:01001654 ! aerosol formation process
is_a: ENVO:02500003 ! atmospheric process
intersection_of: ENVO:01001654 ! aerosol formation process
intersection_of: BFO:0000066 ENVO:01000267 ! occurs in atmosphere

[Term]
id: ENVO:01001086
name: formation of a solid aerosol in an atmosphere
def: "A process during which an aerosol, consisting of solid particulates suspended in a gas, is formed in an atmosphere." [https://en.wikipedia.org/wiki/Particulates]
is_a: ENVO:01001085 ! atmospheric aerosol formation
intersection_of: ENVO:01001085 ! atmospheric aerosol formation
intersection_of: RO:0002234 ENVO:01001089 ! has output aerosolised solids
relationship: RO:0002234 ENVO:01001089 ! has output aerosolised solids

[Term]
id: ENVO:01001087
name: formation of a liquid aerosol in an atmosphere
def: "A process during which an aerosol, consisting of droplets of liquid suspended in gas, is formed in an atmosphere." [https://en.wikipedia.org/wiki/Particulates]
is_a: ENVO:01001085 ! atmospheric aerosol formation
intersection_of: ENVO:01001085 ! atmospheric aerosol formation
intersection_of: RO:0002234 ENVO:01001088 ! has output aerosolised liquids
relationship: RO:0002234 ENVO:01001088 ! has output aerosolised liquids

[Term]
id: ENVO:01001088
name: aerosolised liquids
def: "An aerosol which has non-gaseous parts that are primarily composed of liquid droplets." [https://en.wikipedia.org/wiki/Aerosol]
synonym: "liquid aerosol" EXACT []
xref: SWEETRealm:Aerosol
is_a: ENVO:00010505 ! aerosol
is_a: ENVO:02000140 ! fluid environmental material
relationship: RO:0002219 ENVO:00002005 ! surrounded by air

[Term]
id: ENVO:01001089
name: aerosolised solids
def: "An aerosol which has non-gaseous parts that are primarily composed of solid particles." [https://en.wikipedia.org/wiki/Aerosol]
synonym: "solid aerosol" EXACT []
xref: SWEETRealm:Aerosol
is_a: ENVO:00010505 ! aerosol
relationship: RO:0002219 ENVO:00002005 ! surrounded by air

[Term]
id: ENVO:01001090
name: formation of a solid aerosol from gaseous material in an atmosphere
def: "A process during which microscopic solid particulates are formed from gaseous materials in an atmosphere." [https://en.wikipedia.org/wiki/Particulates]
is_a: ENVO:01001086 ! formation of a solid aerosol in an atmosphere
intersection_of: ENVO:01001086 ! formation of a solid aerosol in an atmosphere
intersection_of: RO:0002233 ENVO:01000797 ! has input gaseous environmental material
intersection_of: RO:0002234 ENVO:01001089 ! has output aerosolised solids
relationship: RO:0002233 ENVO:01000797 ! has input gaseous environmental material

[Term]
id: ENVO:01001091
name: formation of a liquid aerosol from gaseous material in an atmosphere
def: "A process during which microscopic liquid droplets are formed from gaseous materials in an atmosphere." [https://en.wikipedia.org/wiki/Particulates]
synonym: "atmospheric formation of a liquid aerosol" EXACT []
synonym: "formation of a liquid aerosol in an atmosphere" EXACT []
synonym: "formation of a liquid aerosol in the atmosphere" EXACT []
is_a: ENVO:01001087 ! formation of a liquid aerosol in an atmosphere
intersection_of: ENVO:01001087 ! formation of a liquid aerosol in an atmosphere
intersection_of: RO:0002233 ENVO:01000797 ! has input gaseous environmental material
intersection_of: RO:0002234 ENVO:01001088 ! has output aerosolised liquids
relationship: RO:0002233 ENVO:01000797 ! has input gaseous environmental material

[Term]
id: ENVO:01001093
name: tectonic movement
def: "A process during which pieces of a planetary crust and uppermost mantle move." [https://en.wikipedia.org/wiki/Plate_tectonics] {comment="https://en.wikipedia.org/wiki/List_of_tectonic_plates"}
is_a: ENVO:03000010 ! material transport process
relationship: RO:0000057 ENVO:01001097 ! has participant tectonic plate

[Term]
id: ENVO:01001097
name: tectonic plate
def: "A part of a lithosphere which is separated by other such parts by geographic faults or similar geomorphological discontinuities." [https://en.wikipedia.org/wiki/List_of_tectonic_plates]
is_a: ENVO:00000191 ! solid astronomical body part
relationship: BFO:0000050 ENVO:01000646 ! part of lithosphere
relationship: RO:0000086 PATO:0002253 ! has quality platelike
relationship: RO:0002131 ENVO:01001098 ! overlaps tectonic plate boundary

[Term]
id: ENVO:01001098
name: tectonic plate boundary
def: "A geomorphological feature which is formed where two or more tectonic plates move towards, away from, or along one another, resulting in deformation of the lithosphere." [https://en.wikipedia.org/wiki/Plate_tectonics]
is_a: ENVO:01000408 ! environmental zone
relationship: RO:0000086 PATO:0001199 ! has quality linear
relationship: RO:0002180 ENVO:01001097 ! has component tectonic plate
relationship: RO:0002180 ENVO:01001097 {minCardinality="2"} ! has component tectonic plate
relationship: RO:0002354 ENVO:01001093 ! formed as result of tectonic movement

[Term]
id: ENVO:01001110
name: ecosystem
def: "An environmental system which includes both living and non-living components." [https://en.wikipedia.org/wiki/Ecosystem]
comment: This class will be primarily filled by inference, any environmental system which necessarily includes living parts should be autoclassified here.
xref: LTER:173 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=173&/ecosystems"}
is_a: ENVO:01000254 ! environmental system

[Term]
id: ENVO:01001120
name: animal manure product
def: "A product which is composed primarily of animal manure that has been heat treated and packaged as a product for commercial or consumer use." [http://orcid.org/0000-0002-8844-9165]
is_a: ENVO:00003074 ! manufactured product
relationship: RO:0002473 ENVO:00003031 ! composed primarily of animal manure

[Term]
id: ENVO:01001122
name: gas planet
def: "A planet which is primarily composed of hydrogen and helium." [http://solarsystem.nasa.gov/planets/whatisaplanet, https://en.wikipedia.org/wiki/List_of_planet_types, https://en.wikipedia.org/wiki/Planet]
comment: Gas giants are composed of about 90% hydrogen and helium. Jupiter and Saturn are examples of gas giants.
is_a: ENVO:01000800 ! planet
is_a: ENVO:01001686 ! mass of environmental material
relationship: RO:0002473 ENVO:01001155 ! composed primarily of astrogeological gas

[Term]
id: ENVO:01001125
name: ice
def: "An ice is an environmental material which is either frozen or which is maintained in a solid state by gravitational forces or pressure." []
comment: Note that ice may be formed at very high temperatures, due to gravitational effects and/or pressure.
is_a: ENVO:01000814 ! solid environmental material

[Term]
id: ENVO:01001135
name: desert planet
def: "A terrestrial planet which has a surface dominated by hot deserts." []
comment: This class of planet is still mostly theoretical.
synonym: "dry planet" EXACT []
is_a: ENVO:01000958 ! terrestrial planet

[Term]
id: ENVO:01001136
name: ocean planet
def: "A planet which has a surface layer that nearly completely or completely covered by water, and which has a substantial portion of its mass composed of water." [https://en.wikipedia.org/wiki/Ocean_planet]
comment: While this planetary form is still mostly theoretical, strong candidates exist such as the extrasolar planet GJ 1214 b and ocean planet candidate Kepler-22b.
synonym: "aquaplanet" EXACT []
synonym: "panthalassic planet" EXACT []
synonym: "water world" EXACT []
is_a: ENVO:01000800 ! planet

[Term]
id: ENVO:01001137
name: ice planet
def: "A planet which has a surface layer that nearly completely or completely covered by ice, and which has a substantial portion of its mass composed of ice." [https://en.wikipedia.org/wiki/Ice_planet]
comment: While this planetary form is still mostly theoretical, strong candidates exist such as OGLE-2005-BLG-390Lb, OGLE-2013-BLG-0341L b and MOA-2007-BLG-192Lb. Pluto was considered an ice planet until its reclassification in 2006 CE.  Surface temperatures of ice planets would have to be below 260 K (−13°C) if composed primarily of water, below 180 K (−93°C) if primarily composed of CO2 and ammonia, and below 80 K (−193°C) if composed primarily of methane. {xref="https://en.wikipedia.org/wiki/Ice_planet"}
synonym: "cryoplanet" EXACT []
is_a: ENVO:01000800 ! planet

[Term]
id: ENVO:01001138
name: carbon dioxide ice
def: "Ice which is primarily composed of carbon dioxide." [https://en.wikipedia.org/wiki/Ice]
is_a: ENVO:01001125 ! ice
intersection_of: ENVO:01001125 ! ice
intersection_of: RO:0002473 CHEBI:16526 ! composed primarily of carbon dioxide
relationship: RO:0002473 CHEBI:16526 ! composed primarily of carbon dioxide

[Term]
id: ENVO:01001140
name: ammonia ice
def: "Ice which is primarily composed of ammonia." [https://en.wikipedia.org/wiki/Ice]
is_a: ENVO:01001125 ! ice
intersection_of: ENVO:01001125 ! ice
intersection_of: RO:0002473 CHEBI:16134 ! composed primarily of ammonia
relationship: RO:0002473 CHEBI:16134 ! composed primarily of ammonia

[Term]
id: ENVO:01001141
name: carbon monoxide ice
def: "Ice which is primarily composed of carbon monoxide." [https://en.wikipedia.org/wiki/Ice]
is_a: ENVO:01001125 ! ice
intersection_of: ENVO:01001125 ! ice
intersection_of: RO:0002473 CHEBI:17245 ! composed primarily of carbon monoxide
relationship: RO:0002473 CHEBI:17245 ! composed primarily of carbon monoxide

[Term]
id: ENVO:01001143
name: lava planet
def: "A planet which has a surface layer that nearly completely or completely covered by lava, and which has a substantial portion of its mass composed of lava." [https://en.wikipedia.org/wiki/Lava_planet]
comment: This class of planets is still mostly theoretical, however, lava planets are thought plausible shortly after a terrestrial planet is formed, soon after a terrestrial planet has suffered a large collision event, or if a terrestrial planet is orbiting very close to its star, causing intense irradiation and tidal forces.  Likely lava exoplanets include COROT-7b, Kepler-10b, Alpha Centauri Bb, and Kepler-78b. {xref="https://en.wikipedia.org/wiki/Lava_planet"}
is_a: ENVO:01000800 ! planet

[Term]
id: ENVO:01001147
name: helium planet
def: "A gas planet which has an atmosphere composed primarily of helium." [https://en.wikipedia.org/wiki/Helium_planet]
comment: A helium planet might form via hydrogen evaporation from a gaseous planet orbiting close to a star. Low-mass white dwarfs may transition into objects which are essentially helium planets by hydrogen depletion through mass transfer to a massive object such as a neutron star.  Gliese 436 b is a candidate helium planet. {xref="https://en.wikipedia.org/wiki/Helium_planet"}
is_a: ENVO:01001122 ! gas planet

[Term]
id: ENVO:01001150
name: protoplanetary disk
def: "An astronomical object which is composed of dense gas and dust rotating around a young newly formed star, a T Tauri star, or a Herbig Ae/Be star in a disk-shaped configuration." [https://en.wikipedia.org/wiki/Protoplanetary_disk]
is_a: ENVO:01000804 ! astronomical object

[Term]
id: ENVO:01001154
name: volatile astrogeological material
def: "A material which is composed primarily of chemical elements and compounds with relatively low boiling points, equilibrium condensation temperatures below 1300 Kelvin, and which are part of the crust or atmosphere of a moon or planet." [https://en.wikipedia.org/wiki/Volatiles]
comment: Examples include nitrogen, water, carbon dioxide, ammonia, hydrogen, methane and sulfur dioxide. In astrogeology, these compounds, in their solid state, often comprise large proportions of the crusts of moons and dwarf planets. {xref="https://en.wikipedia.org/wiki/Volatiles"}
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:01001155
name: astrogeological gas
def: "An astrogeological volatile which is composed primarily of chemical compounds with boiling points around those of hydrogen and helium." [https://en.wikipedia.org/wiki/Volatiles]
comment: This is a term native to the fields of planetary science and astrophysics.  Hydrogen has a boiling point of 20.271 Kelvin and a melting point of 13.99 Kelvin. Helium has a boiling point of 4.222 Kelvin and a melting point of 0.95 Kelvin.
is_a: ENVO:01001154 ! volatile astrogeological material

[Term]
id: ENVO:01001164
name: geodiversity
def: "A quality which inheres in a astronomical body or astronomical body part by virtue of the variation in its material composition, participation in geological processes, and the variation in is land- and hydroforms." [https://en.wikipedia.org/wiki/Geodiversity]
comment: Materials which are usually assessed when appraising geodiversity include minerals, rocks, sediments, fossils, soils and water. Landforms factored into geodiversity metrics typically include folds, faults, and other expressions of morphology or relations between units of earth material. Natural processes that are included in measures of geodiversity are those which either maintain or change materials or geoforms, including tectonics, sediment transport, and pedogenesis. Geodiversity does not usually factor in anthropogenic entities. {xref=""}
is_a: PATO:0001241 ! physical object quality

[Term]
id: ENVO:01001167
name: ecosystem fragment
def: "An ecosystem which has been causally isolated from a larger ecosystem within which it was previously embedded, such that the direct exchange of materials, resources, and energy between these systems is severely or entirely curtailed." []
comment: Often, ecosystem fragments are unable to sustain themselves without human intervention and management as they are not large enough to perform self-sustaining functions (e.g. nutrient recycling) or hold sufficient ecological resources such as genetic diversity of populations.
is_a: ENVO:01001110 ! ecosystem
relationship: RO:0002354 ENVO:01001168 ! formed as result of ecosystem fragmentation process

[Term]
id: ENVO:01001168
name: ecosystem fragmentation process
def: "A process during which one or more parts of an ecosystem become causally isolated such that the direct flow or exchange of materials, resources, and energy between a given fragment and the remainder of the original system is severely curtailed or entirely halted." [https://en.wikipedia.org/wiki/Ecosystem_decay, https://en.wikipedia.org/wiki/Habitat_fragmentation, https://en.wikipedia.org/wiki/Population_fragmentation]
is_a: ENVO:01001795 ! ecosystem process
is_a: GO:0008150 ! biological_process
intersection_of: ENVO:01001795 ! ecosystem process
intersection_of: RO:0002233 ENVO:01001110 ! has input ecosystem
intersection_of: RO:0002297 ENVO:01001167 ! results in formation of anatomical entity ecosystem fragment
relationship: RO:0002233 ENVO:01001110 ! has input ecosystem
relationship: RO:0002297 ENVO:01001167 ! results in formation of anatomical entity ecosystem fragment
relationship: RO:0002418 ENVO:01001174 ! causally upstream of or within ecosystem decay

[Term]
id: ENVO:01001170
name: active ecosystem management process
def: "A process during which an ecosystem, its parts, or the processes it participates in are modified by human intervention to accomplish an objective." [https://www.iucn.org/theme/protected-areas/about/protected-areas-categories/category-iv-habitatspecies-management-area]
synonym: "ecosystem management" EXACT []
is_a: BFO:0000003 ! occurrent
is_a: ENVO:02500026 ! anthropogenic modulatory intervention process
relationship: RO:0000057 ENVO:01001110 ! has participant ecosystem
relationship: RO:0002608 NCBITaxon:9606 ! process has causal agent Homo sapiens

[Term]
id: ENVO:01001174
name: ecosystem decay
def: "A process during which an ecosystem fragment loses its system integrity, with many of its resident ecological populations 1) losing their habitats, 2) undergoing a loss of functional and phylogenetic diversity, and 3) undergoing a subsequent genetic destabilisation through inbreeding." [https://en.wikipedia.org/wiki/Ecosystem_decay]
comment: This process may be caused by direct anthropisation (i.e. the fragmentation of ecosystems due to the establishment of cropland) or by more natural events such as forest fires or erosion of land bridges.
is_a: ENVO:01001795 ! ecosystem process
relationship: RO:0000057 ENVO:01000739 ! has participant habitat
relationship: RO:0000057 ENVO:01001167 ! has participant ecosystem fragment
relationship: RO:0002427 ENVO:01001168 ! causally downstream of or within ecosystem fragmentation process

[Term]
id: ENVO:01001179
name: cnidarian-associated environment
def: "An environmental system determined by a cnidarian or part of a cnidarian." []
is_a: ENVO:01001002 ! animal-associated environment

[Term]
id: ENVO:01001185
name: acidic soil
def: "Soil which has increased levels of molecules or ions capable of donating a hydron (proton or hydrogen ion) to other chemical entities, or, alternatively, capable of forming covalent bonds with other chemicals via the acceptance of an electron pair, resulting in a bulk pH measurement of less than 7." [https://en.wikipedia.org/wiki/Acid]
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0000086 PATO:0001429 ! has quality acidic
relationship: RO:0000086 PATO:0001429 ! has quality acidic

[Term]
id: ENVO:01001186
name: acidic volcanic ash
def: "Volcanic ash which has increased levels of molecules or ions capable of donating a hydron (proton or hydrogen ion) to other chemical entities, or, alternatively, capable of forming covalent bonds with other chemicals via the acceptance of an electron pair, resulting in a bulk pH measurement of less than 7." []
is_a: ENVO:01000701 ! volcanic ash
intersection_of: ENVO:01000701 ! volcanic ash
intersection_of: RO:0000086 PATO:0001429 ! has quality acidic
relationship: RO:0000086 PATO:0001429 ! has quality acidic

[Term]
id: ENVO:01001191
name: water surface
def: "The surface layer of a volume of water." []
synonym: "surface of a body of water" EXACT []
synonym: "water body surface" EXACT []
xref: EcoLexicon:surface_water
xref: https://en.wikipedia.org/wiki/Surface_water
xref: SWEETRealm:SurfaceWater
is_a: ENVO:01000325 ! aquatic layer
is_a: ENVO:01001310 ! liquid surface layer
intersection_of: ENVO:01001310 ! liquid surface layer
intersection_of: BFO:0000050 ENVO:00002006 ! part of liquid water
relationship: BFO:0000050 ENVO:00002006 ! part of liquid water

[Term]
id: ENVO:01001192
name: sediment surface
def: "The surface layer of a mass of sediment." []
synonym: "surface of a sedimentary mass" EXACT []
synonym: "surface sediment" EXACT []
is_a: ENVO:00010504 ! surface layer
intersection_of: ENVO:00010504 ! surface layer
intersection_of: BFO:0000050 ENVO:00002007 ! part of sediment
relationship: BFO:0000050 ENVO:00002007 ! part of sediment

[Term]
id: ENVO:01001195
name: radiation shielding disposition
def: "An environmental disposition which inheres in an entity that intercepts, attenuates, or blocks radiation." []
is_a: ENVO:01000452 ! environmental disposition

[Term]
id: ENVO:01001199
name: terrestrial environmental zone
def: "An environmental zone which is bounded by material parts of a land mass or the atmosphere or space adjacent to it." []
is_a: ENVO:01000408 ! environmental zone
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:01000408 ! environmental zone
intersection_of: BFO:0000050 ENVO:01000635 ! part of planetary landmass
relationship: BFO:0000050 ENVO:00000446 ! part of terrestrial biome
relationship: BFO:0000050 ENVO:01000635 ! part of planetary landmass

[Term]
id: ENVO:01001200
name: anthropised terrestrial environmental zone
def: "A terrestrial zone which is bounded by constructed, manufactured, or other anthropogenic material entities." []
is_a: ENVO:01001199 ! terrestrial environmental zone
intersection_of: ENVO:01001199 ! terrestrial environmental zone
intersection_of: BFO:0000050 ENVO:01000219 ! part of anthropogenic terrestrial biome
relationship: BFO:0000050 ENVO:01000219 ! part of anthropogenic terrestrial biome

[Term]
id: ENVO:01001205
name: lithification
def: "A process during which sediments compact under pressure, expel connate fluids, and gradually become solid sedimentary rock." [https://en.wikipedia.org/wiki/Lithification]
is_a: ENVO:03000043 ! material transformation process
is_a: GO:0008150 ! biological_process
intersection_of: ENVO:03000043 ! material transformation process
intersection_of: RO:0002233 ENVO:00002007 ! has input sediment
intersection_of: RO:0002297 ENVO:00002016 ! results in formation of anatomical entity sedimentary rock
relationship: RO:0002233 ENVO:00002007 ! has input sediment
relationship: RO:0002297 ENVO:00002016 ! results in formation of anatomical entity sedimentary rock

[Term]
id: ENVO:01001206
name: grassland ecosystem
def: "An ecosystem in which grasses (Graminae) are the dominant form of vegetation and determine the system's structure and dynamics." [https://en.wikipedia.org/wiki/Grassland]
synonym: "GRASSLAND" EXACT [USGS:SDTS]
synonym: "grassland" EXACT [Geonames:feature]
xref: EcoLexicon:grassland
xref: FTT:259
xref: FTT:760
xref: FTT:766
xref: Geonames:V.GRSLD
xref: LTER:232
xref: TGN:21604
xref: TGN:54052
is_a: ENVO:01001790 ! terrestrial ecosystem

[Term]
id: ENVO:01001209
name: wetland ecosystem
def: "A terrestrial ecosystem which is inundated or saturated by surface or ground water at a frequency and duration sufficient to support, and that under normal circumstances does support, a prevalence of vegetation typically adapted for life in saturated soil conditions." [https://en.wikipedia.org/wiki/Wetland]
synonym: "WETLAND" EXACT [USGS:SDTS]
synonym: "Wetland" EXACT [NASA:earthrealm]
xref: EcoLexicon:wetland
xref: FTT:1001
xref: FTT:1060
xref: FTT:1061
xref: FTT:1118
xref: FTT:1180
xref: FTT:1190
xref: FTT:1206
xref: FTT:1207
xref: FTT:1226
xref: FTT:184
xref: FTT:185
xref: FTT:228
xref: FTT:281
xref: FTT:480
xref: FTT:716
xref: FTT:883
xref: FTT:934
xref: FTT:945
xref: FTT:983
xref: Geonames:H.WTLD
xref: https://en.wikipedia.org/wiki/Wetland
xref: LTER:630
xref: SPIRE:Bog
xref: SWEETRealm:Wetland
xref: TGN:21301
xref: TGN:21304
xref: TGN:21305
is_a: ENVO:01001110 ! ecosystem

[Term]
id: ENVO:01001210
name: defence against flooding
def: "A planned process during which an environmental system is modified to mitigate or nullify the impacts of flooding." []
synonym: "defense against flooding" EXACT []
is_a: BFO:0000015 ! process
is_a: ENVO:02500026 ! anthropogenic modulatory intervention process
intersection_of: ENVO:02500026 ! anthropogenic modulatory intervention process
intersection_of: RO:0002212 ENVO:02500002 ! negatively regulates flooding
relationship: RO:0002212 ENVO:02500002 ! negatively regulates flooding

[Term]
id: ENVO:01001211
name: stellar radiation
def: "An electromagnetic radiation process during which electromagnetic waves or their quanta are emitted from a star." [https://en.wikipedia.org/wiki/Electromagnetic_radiation, https://en.wikipedia.org/wiki/Solar_irradiance]
xref: NCIT:C44445
is_a: ENVO:01001026 ! electromagnetic radiation
intersection_of: ENVO:01001026 ! electromagnetic radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star
relationship: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001212
name: microwave stellar radiation
def: "A stellar radiation process during which electromagnetic waves or their quanta are emitted from a star at wavelengths and frequencies which travel exclusively in a line-of-sight fashion and which may produce molecular rotation and torsion on contact with matter." [https://en.wikipedia.org/wiki/Microwave, https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
comment: This definition focuses on the properties of microwaves rather than their wavelength or frequency limits. Considerable ambiguity exists around the wavelength and frequency thresholds of microwaves. The ISO 21348 definition bounds these waves at 1 mm and 15 mm, with frequencies between 100 GHz and 0.225 GHz.
is_a: ENVO:01001211 ! stellar radiation
is_a: ENVO:21001212 ! microwave radiation
intersection_of: ENVO:21001212 ! microwave radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001213
name: radio wave stellar radiation
def: "A stellar radiation process during which electromagnetic waves or their quanta are emitted from a star at wavelengths ranging from millimetre to kilometer scales." [https://en.wikipedia.org/wiki/Radio_wave, https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
comment: As with microwaves, considerable variation exists in the delimitation of frequency and wavelength thresholds for radiowaves. The ISO 21348 standard allows a wavelength range of 0.10 mm to 100 m and a frequency range of 300 GHz to 3 MHz. However, much lower thresholds also exist.
is_a: ENVO:01001211 ! stellar radiation
is_a: ENVO:21001213 ! radio wave radiation
intersection_of: ENVO:21001213 ! radio wave radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001214
name: infrared stellar radiation
def: "A stellar radiation process during which electromagnetic waves or their quanta are emitted from a star when molecules change their rotational-vibrational movements, usually at wavelengths between 760 nm and 1 mm." [https://en.wikipedia.org/wiki/Infrared, https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
synonym: "infra-red stellar radiation" EXACT []
is_a: ENVO:01001211 ! stellar radiation
is_a: ENVO:21001214 ! infrared radiation
intersection_of: ENVO:21001214 ! infrared radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001215
name: visible spectrum stellar radiation
def: "A stellar radiation process during which electromagnetic waves or their quanta are emitted from a star at wavelengths between 380 nm and 760 nm." [https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
synonym: "optical stellar radiation" EXACT []
is_a: ENVO:01001211 ! stellar radiation
is_a: ENVO:21001215 ! visible spectrum radiation
intersection_of: ENVO:21001215 ! visible spectrum radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001216
name: ultraviolet stellar radiation
def: "A stellar radiation process during which electromagnetic waves or their quanta are emitted from a star at wavelengths between 10 nm and 400 nm." [https://en.wikipedia.org/wiki/Ultraviolet, https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
xref: NCIT:C17231
is_a: ENVO:01001211 ! stellar radiation
is_a: ENVO:21001216 ! ultraviolet radiation
intersection_of: ENVO:21001216 ! ultraviolet radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001217
name: X-ray stellar radiation
def: "A stellar radiation process during which penetrating electromagnetic radiation is emitted by high-energy electrons as they fall into a lower state of energy." [https://en.wikipedia.org/wiki/X-ray]
comment: Ambiguity exists in the definition of x-rays and their differentiation from gamma rays. Photons with sufficient energy to be classified as x-rays may be emitted by other processes than electrons falling to lower energy states. Most x-rays have wavelengths ranging from 0.01 to 10 nanometers, corresponding to frequencies in the range of 30 petahertz to 30 exahertz and energies in the range of 100 eV to 100 keV. {xref="https://en.wikipedia.org/wiki/X-ray#Energy_ranges"}
synonym: "x ray stellar radiation" EXACT []
is_a: ENVO:01001219 ! ionizing stellar radiation
is_a: ENVO:21001217 ! X-ray radiation
intersection_of: ENVO:21001217 ! X-ray radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001218
name: gamma-ray stellar radiation
def: "A stellar radiation process during which penetrating electromagnetic radiation is emitted from the radioactive decay (gamma decay) of atomic nuclei." [https://en.wikipedia.org/wiki/Gamma_ray]
comment: Ambiguity exists in the definition of gamma rays. As a rule of thumb, gamma rays have energies above 100 keV, frequencies above 10 exahertz, and wavelengths less than 10 picometers. However, regardless of the energy released, electromagnetic radiation from radioactive decay of atomic nuclei is referred to as "gamma rays". In astronomy, however, gamma rays are defined by their energy, and no production process needs to be specified. {xref="https://en.wikipedia.org/wiki/Gamma_ray"}
is_a: ENVO:01001219 ! ionizing stellar radiation
is_a: ENVO:21001218 ! gamma-ray radiation
intersection_of: ENVO:21001218 ! gamma-ray radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001219
name: ionizing stellar radiation
def: "A stellar radiation process during which electromagnetic waves or their quanta are emitted from a star with sufficient energy to disrupt molecular bonds or alter the electron number of atoms." [https://en.wikipedia.org/wiki/Electromagnetic_radiation, https://en.wikipedia.org/wiki/Solar_irradiance]
synonym: "ionising stellar radiation" EXACT []
is_a: ENVO:01001211 ! stellar radiation
is_a: ENVO:21001219 ! ionizing radiation
intersection_of: ENVO:21001219 ! ionizing radiation
intersection_of: RO:0002608 ENVO:01000801 ! process has causal agent star

[Term]
id: ENVO:01001220
name: water accumulation process
def: "A process during which liquid water accumulates in a site, most often in some form of container." []
is_a: ENVO:01001856 ! liquid accumulation process
is_a: ENVO:02500031 ! hydrological process
relationship: RO:0000057 ENVO:00002006 ! has participant liquid water
relationship: RO:0002234 ENVO:00000063 ! has output water body

[Term]
id: ENVO:01001222
name: commercial building
def: "A building which is primarily used to facilitate the buying or selling of goods or services." [https://en.wikipedia.org/wiki/Commercial_building]
comment: "Commerce includes legal, economic, political, social, cultural and technological systems that are in operation in any country or internationally." {xref="https://en.wikipedia.org/wiki/Commerce"}
is_a: ENVO:00000073 ! building
intersection_of: ENVO:00000073 ! building
intersection_of: RO:0000056 ENVO:01001451 ! participates in usage of an environment for business
relationship: RO:0000056 ENVO:01001451 ! participates in usage of an environment for business

[Term]
id: ENVO:01001223
name: lumber production process
def: "A process during which wood is processed into beams or planks." [https://en.wikipedia.org/wiki/Lumber]
synonym: "lumber production" EXACT []
synonym: "timber production" EXACT []
synonym: "timber production process" EXACT []
is_a: ENVO:01000994 ! planetary manufacturing process

[Term]
id: ENVO:01001224
name: office
def: "A building part within which administrative work is done by an organisations users in order to support and realise the objectives of that organization." [https://en.wikipedia.org/wiki/Office#Office_buildings]
is_a: ENVO:01000420 ! building part

[Term]
id: ENVO:01001226
name: terrestrial natural environment
def: "A natural environment which is located on a land mass." []
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01000951 ! natural environment
intersection_of: ENVO:01000951 ! natural environment
intersection_of: BFO:0000050 ENVO:01000635 ! part of planetary landmass
relationship: BFO:0000050 ENVO:01000635 ! part of planetary landmass

[Term]
id: ENVO:01001227
name: aquatic natural environment
def: "A natural environment which is within a water body." []
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01000951 ! natural environment
intersection_of: ENVO:01000951 ! natural environment
intersection_of: BFO:0000050 ENVO:00000063 ! part of water body
relationship: BFO:0000050 ENVO:00000063 ! part of water body

[Term]
id: ENVO:01001239
name: forest canopy
xref: EcoLexicon:canopy
xref: https://en.wikipedia.org/wiki/Canopy
xref: LTER:82
xref: SWEETRealm:Canopy
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01001242 ! canopy
relationship: BFO:0000050 ENVO:01001243 ! part of forest ecosystem

[Term]
id: ENVO:01001242
name: canopy
def: "A vegetation layer which is formed by a collection of individual plant crowns, themselves constituting part of the aboveground portion of a plant community." [https://en.wikipedia.org/wiki/Canopy_%28biology%29]
xref: EcoLexicon:canopy
xref: LTER:82
xref: SWEETRealm:Canopy
is_a: ENVO:01000355 ! vegetation layer

[Term]
id: ENVO:01001243
name: forest ecosystem
def: "An ecosystem which is determined by communities of plants with a tree growth form and in which members of those communities form continuous or discontinuous regions of canopy cover." [http://www.fao.org/docrep/017/ap862e/ap862e00.pdf] {comment="https://www1.usgs.gov/csas/nvcs/nvcsGetUnitDetails?elementGlobalId=860217"}
comment: The definitions of forest can vary greatly, and different classes will be needed to support the major categories. Tree cover alone is not enough to distinguish between forests and plantations. The international definition proposed by the 2010 FAO Forestry Resource Assessment: "land spanning more than 0.5 ha with trees higher than 5 metres and canopy cover of more than 10 percent, or trees able to reach these thresholds in situ . It does not include land that is predominantly under agricultural or urban land use." - FAO.  2010. Global forest resources assessment 2010, Main report, FAO Forestry Paper 163. Rome.
is_a: ENVO:01001790 ! terrestrial ecosystem
relationship: BFO:0000051 ENVO:01001239 ! has part forest canopy

[Term]
id: ENVO:01001244
name: cropland ecosystem
def: "An ecosystem which 1) is determined by communities of annual crops, perennial woody crops, or by actively tilled land, 2) is primarily used for agricultural activity, and 3) contains no village or larger human settlement." [http://dx.doi.org/10.1890/070062]
is_a: ENVO:01001790 ! terrestrial ecosystem
is_a: ENVO:01001828 ! anthropised ecosystem

[Term]
id: ENVO:01001246
name: agricultural process
def: "A process during which humans rear animals or plants on land for harvest and consumption." [] {comment="http://www.fao.org/docrep/003/x6941e/x6941e04.htm#bm04"}
is_a: ENVO:02500027 ! anthropogenic environmental process
relationship: BFO:0000066 ENVO:01000635 ! occurs in planetary landmass

[Term]
id: ENVO:01001265
name: thermal pollution
def: "An environmental pollution process during which the temperature of an environmental system, or parts thereof, is raised above its natural levels." [https://en.wikipedia.org/wiki/Thermal_pollution]
is_a: ENVO:02500036 ! environmental pollution

[Term]
id: ENVO:01001266
name: thermal pollution of an aquatic system
def: "A thermal pollution process which occurs in a water body or aquatic environment." [https://en.wikipedia.org/wiki/Thermal_pollution]
is_a: ENVO:01001265 ! thermal pollution
is_a: ENVO:02500031 ! hydrological process
is_a: ENVO:02500039 ! water pollution
relationship: BFO:0000066 ENVO:00000063 ! occurs in water body
relationship: BFO:0000066 ENVO:01000317 ! occurs in aquatic environment

[Term]
id: ENVO:01001271
name: impermeable surface layer
def: "A surface layer through which liquids or gases cannot pass." [https://en.wikipedia.org/wiki/Impervious_surface]
is_a: ENVO:01001311 ! solid surface layer
intersection_of: ENVO:01001311 ! solid surface layer
intersection_of: RO:0000086 PATO:0000983 ! has quality impermeable
relationship: RO:0000086 PATO:0000983 ! has quality impermeable

[Term]
id: ENVO:01001272
name: constructed pavement
def: "A construction which comprises a durable surface layer overlying a solid surface intended to sustain vehicular or foot traffic." [https://en.wikipedia.org/wiki/Road_surface]
is_a: ENVO:00000010 ! transport feature
relationship: RO:0000086 PATO:0002124 ! has quality laminar

[Term]
id: ENVO:01001273
name: liquid layer
def: "A layer which is primarily composed of some liquid material." []
is_a: ENVO:01001678 ! fluid layer
intersection_of: ENVO:01001678 ! fluid layer
intersection_of: RO:0002473 ENVO:01000815 ! composed primarily of liquid environmental material
relationship: RO:0002473 ENVO:01000815 ! composed primarily of liquid environmental material

[Term]
id: ENVO:01001275
name: solid layer
def: "A layer which is primarily composed of some solid material, allowing for non-solid parts such as interstitial pockets of gas or liquid." []
is_a: ENVO:01000281 ! layer
intersection_of: ENVO:01000281 ! layer
intersection_of: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material
relationship: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material

[Term]
id: ENVO:01001276
name: water ice layer
def: "A solid layer which is primarily composed of some water-based ice." []
is_a: ENVO:01001275 ! solid layer
is_a: ENVO:01001609 ! cryospheric layer
is_a: ENVO:03000110 ! cryoform
intersection_of: ENVO:01001275 ! solid layer
intersection_of: RO:0002473 ENVO:01000277 ! composed primarily of water ice
relationship: RO:0002473 ENVO:01000277 ! composed primarily of water ice

[Term]
id: ENVO:01001279
name: sidewalk
def: "A constructed pavement which is built on the side of a road and intended for foot traffic." [https://en.wikipedia.org/wiki/Sidewalk]
comment: "In some places, the same term may also be used for a paved path, trail or footpath that is not next to a road, for example, a path through a park." {xref="https://en.wikipedia.org/wiki/Sidewalk"}
is_a: ENVO:01001272 ! constructed pavement

[Term]
id: ENVO:01001282
name: silica dust
def: "Dust which is composed primarily of slicon dioxide." []
is_a: ENVO:00002008 ! dust
relationship: RO:0002473 CHEBI:30563 ! composed primarily of silicon dioxide

[Term]
id: ENVO:01001283
name: aluminium dust
def: "Dust which is primarily composed of aluminium particles." []
is_a: ENVO:00002008 ! dust
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0002473 CHEBI:33628 ! composed primarily of elemental aluminium
relationship: RO:0002473 CHEBI:33628 ! composed primarily of elemental aluminium

[Term]
id: ENVO:01001284
name: barium dust
def: "Dust which is primarily composed of barium particles." []
is_a: ENVO:00002008 ! dust

[Term]
id: ENVO:01001285
name: talc dust
def: "Dust which is primarily composed of hydrated magnesium silicate (talc) particles." []
is_a: ENVO:00002008 ! dust
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0002473 CHEBI:32178 ! composed primarily of Talc
relationship: RO:0002473 CHEBI:32178 ! composed primarily of Talc

[Term]
id: ENVO:01001286
name: slate dust
def: "Dust which is primarily composed of slate particles." []
is_a: ENVO:00002008 ! dust
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0001000 ENVO:01000274 ! derives from slate
relationship: RO:0001000 ENVO:01000274 ! derives from slate

[Term]
id: ENVO:01001287
name: industrial fire
def: "A fire which occurs in an industrial area or building." []
is_a: ENVO:01000786 ! fire
intersection_of: ENVO:01000786 ! fire
intersection_of: BFO:0000066 ENVO:00003861 ! occurs in industrial building
relationship: BFO:0000066 ENVO:00003861 ! occurs in industrial building

[Term]
id: ENVO:01001288
name: kaolin dust
def: "Dust which is primarily composed of kaolinite particles." []
synonym: "kaolinite dust" EXACT []
is_a: ENVO:02000100 ! mineral dust
relationship: RO:0002473 CHEBI:140503 ! composed primarily of kaolin

[Term]
id: ENVO:01001293
name: bush area
def: "A vegetated area which has not been cleared or is sparsely settled, usually scrub-covered or forested" [https://www.merriam-webster.com/dictionary/bush#h1]
comment: "Bush" is a rather loosely defined regional term, primarily used in Australia.
is_a: ENVO:01001305 ! vegetated area

[Term]
id: ENVO:01001294
name: convective storm
def: "An atmospheric storm which is generated by the heating and convection of moist and unstable air masses." [http://glossary.ametsoc.org/wiki/Convective_storm, http://www.emdat.be/Glossary]
comment: "Convective storms range from localised thunderstorms (with heavy rain and/or hail, lightning, high winds, tornadoes) to meso-scale, multi-day events." {xref="http://www.emdat.be/Glossary"}
is_a: ENVO:01000877 ! atmospheric storm

[Term]
id: ENVO:01001296
name: tropical storm
def: "A an atmospheric storm which originates over tropical or subtropical waters and possesses a warm-core, non-frontal synoptic-scale cyclone with a low pressure centre, spiral rain bands and strong winds." [http://www.emdat.be/Glossary]
is_a: ENVO:01000877 ! atmospheric storm

[Term]
id: ENVO:01001297
name: cyclone
def: "An atmospheric storm during which a large mass of atmospheric gas rotates around a centre of low atmospheric pressure, generating high winds which spiral towards that centre." [https://en.wikipedia.org/wiki/Cyclone]
is_a: ENVO:01000877 ! atmospheric storm
relationship: RO:0002427 ENVO:01001748 ! causally downstream of or within cyclonic circulation

[Term]
id: ENVO:01001299
name: atmospheric zone
def: "An environmental zone which is part of an atmosphere." []
synonym: "atmospheric area" EXACT []
is_a: ENVO:01000408 ! environmental zone
intersection_of: ENVO:01000408 ! environmental zone
intersection_of: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: BFO:0000050 ENVO:01000267 ! part of atmosphere

[Term]
id: ENVO:01001300
name: area of low atmospheric pressure
def: "A gaseous part of an atmosphere in which gases have reduced atmospheric pressure." []
comment: Air is not specified directly (although the definition subsumes air masses) to allow for other forms of low pressure areas in planetary atmospheres.
is_a: ENVO:01001645 ! gaseous part of an atmosphere

[Term]
id: ENVO:01001301
name: aquatic estuarine layer
def: "A layer of liquid that is part of an estuary." [ORCID:0000-0002-4366-3088]
is_a: ENVO:01000325 ! aquatic layer
is_a: ENVO:01001308 ! hydroform
intersection_of: ENVO:01000325 ! aquatic layer
intersection_of: BFO:0000050 ENVO:00000045 ! part of estuary
relationship: BFO:0000050 ENVO:00000045 ! part of estuary
relationship: RO:0002473 ENVO:01000301 ! composed primarily of estuarine water

[Term]
id: ENVO:01001305
name: vegetated area
def: "A vegetated area is a geographic feature which has ground cover dominated by plant communities." []
is_a: ENVO:01001199 ! terrestrial environmental zone

[Term]
id: ENVO:01001306
name: bone element environment
def: "An environment which is determined by a bone element." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:2100000 ! anatomical entity environment
intersection_of: ENVO:2100000 ! anatomical entity environment
intersection_of: RO:0002507 UBERON:0001474 ! determined by bone element
relationship: RO:0002507 UBERON:0001474 ! determined by bone element

[Term]
id: ENVO:01001308
name: hydroform
def: "A liquid astronomical body part which is primarily composed of a continuous volume of liquid water and is held in shape or sustained by an environmental process." []
comment: Similar, in spirit, to landform.
is_a: ENVO:01001477 ! liquid astronomical body part
intersection_of: ENVO:01001477 ! liquid astronomical body part
intersection_of: BFO:0000050 ENVO:00000063 ! part of water body
intersection_of: RO:0002473 ENVO:00002006 ! composed primarily of liquid water
relationship: BFO:0000050 ENVO:00000063 ! part of water body
relationship: BFO:0000067 ENVO:01000982 ! contains process water flow process
relationship: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01001309
name: liquid air-water interface layer
def: "A liquid surface layer which is in contact with air." []
is_a: ENVO:01001310 ! liquid surface layer
intersection_of: ENVO:01001310 ! liquid surface layer
intersection_of: RO:0002220 ENVO:00002005 ! adjacent to air
relationship: RO:0002220 ENVO:00002005 ! adjacent to air

[Term]
id: ENVO:01001310
name: liquid surface layer
def: "A surface layer which is composed primarily of some liquid." []
is_a: ENVO:01001273 ! liquid layer
is_a: ENVO:01001673 ! fluid surface layer
intersection_of: ENVO:01001673 ! fluid surface layer
intersection_of: RO:0002473 ENVO:01000815 ! composed primarily of liquid environmental material

[Term]
id: ENVO:01001311
name: solid surface layer
def: "A surface layer which is composed primarily of solid environmental material." []
is_a: ENVO:00010504 ! surface layer
is_a: ENVO:01001275 ! solid layer
intersection_of: ENVO:00010504 ! surface layer
intersection_of: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material

[Term]
id: ENVO:01001319
name: saline water body
def: "A body of water which is primarily composed of saline water." []
comment: This class has its subclasses populated by inference.
synonym: "saline body of water" EXACT []
is_a: ENVO:00000063 ! water body
intersection_of: ENVO:00000063 ! water body
intersection_of: RO:0002473 ENVO:00002010 ! composed primarily of saline water
relationship: RO:0002473 ENVO:00002010 ! composed primarily of saline water

[Term]
id: ENVO:01001320
name: fresh water body
def: "A body of water which is primarily composed of freshwater, with low solute content." []
comment: This class has its subclasses primarily populated by inference. The threshold for what constitutes "fresh" water is variable and should typically be deferred to an applicatoin layer resource.
synonym: "fresh body of water" EXACT []
synonym: "freshwater body" EXACT []
xref: LTER:216 {xref="https://vocab.lternet.edu/vocab/vocab/index.php?tema=216&/freshwater"}
is_a: ENVO:00000063 ! water body
intersection_of: ENVO:00000063 ! water body
intersection_of: RO:0002473 ENVO:00002011 ! composed primarily of fresh water
relationship: RO:0002473 ENVO:00002011 ! composed primarily of fresh water

[Term]
id: ENVO:01001321
name: brackish water body
def: "A body of water which is primarily composed of brackish water." []
comment: This class has its subclasses populated by inference.
synonym: "brackish body of water" EXACT []
is_a: ENVO:01001319 ! saline water body
intersection_of: ENVO:00000063 ! water body
intersection_of: RO:0002473 ENVO:00002019 ! composed primarily of brackish water
relationship: RO:0002473 ENVO:00002019 ! composed primarily of brackish water

[Term]
id: ENVO:01001330
name: nitrogen cycling
def: "A biogeochemical cycle which has nitrogen-bearing chemical entities as participants." []
is_a: ENVO:02500009 ! biogeochemical cycling
intersection_of: ENVO:02500009 ! biogeochemical cycling
intersection_of: RO:0002233 CHEBI:25555 ! has input nitrogen atom
relationship: RO:0002233 CHEBI:25555 ! has input nitrogen atom

[Term]
id: ENVO:01001331
name: sulfur cycling
def: "A biogeochemical cycle which has sulfur-bearing chemical entities as participants." []
synonym: "sulphur cycling" EXACT []
is_a: ENVO:02500009 ! biogeochemical cycling
intersection_of: ENVO:02500009 ! biogeochemical cycling
intersection_of: RO:0002233 CHEBI:26833 ! has input sulfur atom
relationship: RO:0002233 CHEBI:26833 ! has input sulfur atom

[Term]
id: ENVO:01001332
name: phosphorous cycling
def: "A biogeochemical cycle which has phosphorous-bearing chemical entities as participants." []
is_a: ENVO:02500009 ! biogeochemical cycling
intersection_of: ENVO:02500009 ! biogeochemical cycling
intersection_of: RO:0002233 CHEBI:28659 ! has input phosphorus atom
relationship: RO:0002233 CHEBI:28659 ! has input phosphorus atom

[Term]
id: ENVO:01001334
name: advective transport process
def: "A material transport process during which a volume of material is displaced due to a disequilibrium in physical forces and during which 1) the qualities that inhere in that volume and 2) the processes that are unfolding within it are largely unchanged." [https://en.wikipedia.org/wiki/Advection, https://en.wikipedia.org/wiki/Intensive_and_extensive_properties]
comment: Advective processes are disjoint from diffusive processes. Typically, fluids are advected.
synonym: "advective transport" EXACT []
is_a: ENVO:03000010 ! material transport process
intersection_of: ENVO:03000010 ! material transport process
intersection_of: RO:0000053 ENVO:01003012 ! has characteristic advective
relationship: BFO:0000051 ENVO:01003010 ! has part convective transport process
relationship: BFO:0000051 ENVO:01003013 ! has part material diffusion process
relationship: RO:0000053 ENVO:01003012 ! has characteristic advective

[Term]
id: ENVO:01001357
name: desert
def: "A landform which has been rendered barren or partially barren by environmental extremes, especially by low rainfall, and which loses more liquid water by evapotranspiration than is supplied by precipitation." []
is_a: ENVO:01001884 ! surface landform
relationship: RO:0002131 ENVO:00000097 ! overlaps desert area

[Term]
id: ENVO:01001359
name: atmospheric aerosolised particle formation event
def: "An aerosol formation event  which occurs in an atmosphere." [https://github.com/EnvironmentOntology/envo/issues/602]
comment: Note that the detection of such events, and thus the thresholds used to define them in the field, are operational and dependent on the technology and observation strategy used. The event must be intense enough, occur in a large enough area, and persist for enough time to allow the formed particle population to be observed. There are no exact or universally agreed upon thresholds for the intensity, area and duration of such events. If elevated new particle formation rate is observed in the atmosphere (away from direct sources of the related gas-phase molecules) for an operationally defined period of time, practitioners often declare that such an event has taken place. {xref="https://github.com/EnvironmentOntology/envo/issues/602"}
is_a: ENVO:01001372 ! aerosolised particle formation event
is_a: ENVO:02500003 ! atmospheric process
intersection_of: ENVO:01001372 ! aerosolised particle formation event
intersection_of: BFO:0000066 ENVO:01000267 ! occurs in atmosphere

[Term]
id: ENVO:01001364
name: climate system
def: "A system which consists of an atmosphere, hydrosphere, cryosphere, land surface, and  biosphere, forced or influenced by external processes." [https://github.com/EnvironmentOntology/envo/issues/604, https://www.ipcc.ch/ipccreports/tar/wg1/040.htm]
comment: This class, from the IPCC report, is naturally focused on the Earth's climate. The report cites the Sun as the agent of the most important forcing processes. It also considers the direct effect of human activities on the climate system an external forcing {xref="https://www.ipcc.ch/ipccreports/tar/wg1/040.htm"}
is_a: ENVO:01000254 ! environmental system

[Term]
id: ENVO:01001366
name: aerosolised particle formation process
def: "A process during which particles suspended in a gaseous medium are formed." [https://en.wikipedia.org/wiki/Aerosol, https://en.wikipedia.org/wiki/Particulates]
synonym: "new particle formation process" EXACT []
is_a: ENVO:01001084 ! particulate matter formation process
relationship: BFO:0000050 ENVO:01001654 ! part of aerosol formation process
relationship: RO:0002233 ENVO:01000797 ! has input gaseous environmental material

[Term]
id: ENVO:01001367
name: primary aerosol formation process
def: "A material transport process during which solid or liquid particles are directly introduced into a volume of gas." [https://en.wikipedia.org/wiki/Aerosol, https://en.wikipedia.org/wiki/Particulates]
is_a: ENVO:03000010 ! material transport process
relationship: RO:0002234 ENVO:00010505 ! has output aerosol

[Term]
id: ENVO:01001372
name: aerosolised particle formation event
def: "An aerosol formation process during which the rate of particle formation exceeds that which is normally present in the site of its occurrence." [] {comment="https://github.com/EnvironmentOntology/envo/issues/602"}
comment: This is similar to the semantics of storms, where increased rates are observed due to external forcings.
is_a: ENVO:01001366 ! aerosolised particle formation process
intersection_of: ENVO:01001366 ! aerosolised particle formation process
intersection_of: RO:0000086 PATO:0000912 ! has quality increased rate
relationship: RO:0000086 PATO:0000912 ! has quality increased rate

[Term]
id: ENVO:01001398
name: aerosolisation of dust
def: "A primary aerosol formation process during which dust particles are suspended in a gaseous medium." []
is_a: ENVO:01001367 ! primary aerosol formation process
relationship: RO:0002233 ENVO:00002008 ! has input dust

[Term]
id: ENVO:01001399
name: atmospheric aerosolisation of dust
def: "A process during which dust is aerosolised in an atmosphere." []
synonym: "dust event" EXACT []
is_a: ENVO:01001398 ! aerosolisation of dust
is_a: ENVO:02500003 ! atmospheric process

[Term]
id: ENVO:01001402
name: haze
def: "An aersolised mass of dust, smoke, or other dry particulates which scatters visible light thus obsscuring visibility through an atmosphere." [https://en.wikipedia.org/wiki/Haze]
is_a: ENVO:01001089 ! aerosolised solids
is_a: ENVO:01001652 ! atmospheric aerosol

[Term]
id: ENVO:01001405
name: laboratory environment
def: "An anthropogenic environment which is bounded by the building envelope of a laboratory and in which a system of manufactured products exert control on one or more of its environmental conditions." []
is_a: ENVO:01000313 ! anthropogenic environment

[Term]
id: ENVO:01001406
name: laboratory facility
def: "A research facility in which systems of manufactured products control internal conditions and in which scientific or technological research, experiments, and measurement may be performed." [https://en.wikipedia.org/wiki/Laboratory]
synonym: "research laboratory" EXACT []
is_a: ENVO:00000469 ! research facility
relationship: BFO:0000051 ENVO:01001405 ! has part laboratory environment

[Term]
id: ENVO:01001414
name: cumulus cloud
def: "A cloud which 1) has been shaped into rising mounds, domes, or towers with a bulging upper part resembling a cauliflower and a near horizontal or ragged base, 2) is mainly composed of water droplets, 3) is located in the low level of the atmosphere (low étage)." [https://cloudatlas.wmo.int/clouds-genera-cumulus.html, https://cloudatlas.wmo.int/clouds-genera.html, https://cloudatlas.wmo.int/docs/Excerpt%20from%20wmo_49-1_final_2017.pdf, https://en.wikipedia.org/wiki/Cloud]
comment: When well-illuminated by sunlight (excluding during sunrise and sunset) cumulus has has brilliant white sunlit parts and a dark grey base. Cumulus clouds have sharp outlines. When of great vertical extent, cumulus may release precipitation in the form of showers of rain, snow or snow pellets. Cumulus clouds usually have their bases in the low atmospheric level (low étage), but their vertical extent is often so great that their tops may reach into the middle and high atmospheric levels (middle and high étage).
synonym: "Cumuluswolke" EXACT []
synonym: "Haufenwolke" EXACT []
synonym: "Kumuluswolke" EXACT []
synonym: "Quellwolke" EXACT []
is_a: ENVO:01001428 ! water-based cloud
is_a: ENVO:01001690 ! mass of liquid
relationship: BFO:0000050 ENVO:03520000 ! part of low atmospheric level
relationship: RO:0000086 PATO:0001789 ! has quality domed
relationship: RO:0002473 ENVO:00002006 ! composed primarily of liquid water

[Term]
id: ENVO:01001415
name: homogenitus cloud
def: "A cloud which is formed by condensation events triggered by some anthropogenic processes or the outputs thereof, such as aircraft contrails or emissions from chimneys." [https://cloudatlas.wmo.int/clouds-genera.html, https://cloudatlas.wmo.int/docs/Excerpt%20from%20wmo_49-1_final_2017.pdf, https://cloudatlas.wmo.int/homogenitus.html, https://en.wikipedia.org/wiki/Cloud]
is_a: ENVO:01001428 ! water-based cloud
intersection_of: ENVO:01001428 ! water-based cloud
intersection_of: RO:0002354 ENVO:02500027 ! formed as result of anthropogenic environmental process
relationship: RO:0002354 ENVO:02500027 ! formed as result of anthropogenic environmental process

[Term]
id: ENVO:01001419
name: cumulonimbus cloud
def: "A cloud which 1) has been shaped into dense, mountain-like forms or one or more tower-like forms with a flattened upper portion, which often spreads out in the shape of an anvil or plume, 2) is composed of water droplets and, especially in its upper portion, ice crystals, 3) is located in the low level of the atmosphere (low étage), but can extend into the middle and high level of the atmosphere." [https://cloudatlas.wmo.int/clouds-genera-cumulonimbus.html, https://cloudatlas.wmo.int/clouds-genera.html, https://cloudatlas.wmo.int/docs/Excerpt%20from%20wmo_49-1_final_2017.pdf, https://en.wikipedia.org/wiki/Cloud]
comment: Cumulonimbus clouds have a very dark base which may be merged with low ragged clouds which frequently form underneath this cloud. The upper portion  may be smooth, fibrous, or striated. Cumulonimbus also contains large raindrops and, often, snowflakes, snow pellets or hailstones. The water droplets and raindrops may be substantially supercooled. Cumulonimbus is frequently associated with precipitation, sometimes in the form of virga. Cumulonimbus is often accompanied by lightning, thunder or hail. Cumulonimbus usually have their bases in the low level, but their vertical extent is often so great that their tops may reach into the middle and high levels.
synonym: "Cumulonibus-Wolke" EXACT []
synonym: "Gewitterwolke" EXACT []
is_a: ENVO:01001428 ! water-based cloud
relationship: RO:0000086 PATO:0000586 ! has quality increased size
relationship: RO:0000086 PATO:0001788 ! has quality increased mass density

[Term]
id: ENVO:01001428
name: water-based cloud
def: "A cloud which is primarily composed of water-based aerosols." [https://cloudatlas.wmo.int/introduction-and-principles-of-cloud-classification.html, https://en.wikipedia.org/wiki/Cloud]
comment: On Earth clouds are formed by the saturation of air in the homosphere when air cools or gains water vapor. Note that this class describes clouds as countable objects, rather than 'cloud material'. It also refers only to clouds made up of a water-based material.
is_a: ENVO:01000760 ! cloud
is_a: ENVO:01001010 ! hydrometeor
relationship: BFO:0000051 ENVO:01000833 ! has part water droplet

[Term]
id: ENVO:01001429
name: land conversion process
def: "An anthropisation process during which terrestrial environments - natural or anthropised - or parts thereof are altered to facilitate human activities such as agriculture, settlement, or commerce." [https://en.wikipedia.org/wiki/Land_development]
comment: Further examples include subdividing real estate into lots, typically for the purpose of building homes and converting unused factories into condominia. {xref="https://en.wikipedia.org/wiki/Land_development"}
synonym: "land conversion" EXACT []
synonym: "land development" EXACT []
is_a: ENVO:01000743 ! land consumption process
relationship: RO:0000057 ENVO:00000446 ! has participant terrestrial biome

[Term]
id: ENVO:01001430
name: agricultural land conversion process
def: "A land conversion process during which terrestrial ecosystems are altered to facilitate agricultural activities such as crop cultivation or the rearing of livestock." [https://en.wikipedia.org/wiki/Land_development]
comment: This process typically relies on the conversion and development of  forests, savannas or grassland. Creation of farmland from wasteland, deserts or previous impervious surfaces is considerably less frequent because of the presence of degraded soil or the lack of fertile soil. {xref="https://en.wikipedia.org/wiki/Land_development"}
synonym: "agricultural land conversion" EXACT []
is_a: ENVO:01001429 ! land conversion process

[Term]
id: ENVO:01001431
name: land use process
def: "An anthropogenic environmental process which includes all human activities undertaken in a natural, semi-natural, or anthropised environment." [https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf, https://en.wikipedia.org/wiki/Land_use]
comment: There are multiple systems of land use classification. This hierarchy aims to be generally applicable, but national systems can be added on request.
is_a: ENVO:01001436 ! planned environmental usage process

[Term]
id: ENVO:01001433
name: terrestrial mining
def: "A land use process during which materials of economic value are extracted from a planet, usually from an orebody, lode, vein, seam, reef or placer deposit." [https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf, https://en.wikipedia.org/wiki/Land_use, https://en.wikipedia.org/wiki/Mining, https://www.eionet.europa.eu/gemet/en/concept/14837]
is_a: ENVO:01001431 ! land use process
is_a: ENVO:01001437 ! mining

[Term]
id: ENVO:01001434
name: anthropogenic ecosystem conversion process
def: "A process during which an ecosystem - natural or anthropised - is changed by the actions of humans." []
is_a: ENVO:02500027 ! anthropogenic environmental process

[Term]
id: ENVO:01001436
name: planned environmental usage process
def: "A planned process during which humans access and obtain resources, benefits, or services from a natural or anthropised ecosystem." []
is_a: BFO:0000003 ! occurrent
relationship: BFO:0000051 ENVO:01000952 ! has part anthropisation
relationship: BFO:0000051 ENVO:01001170 ! has part active ecosystem management process
relationship: RO:0002608 NCBITaxon:9606 ! process has causal agent Homo sapiens

[Term]
id: ENVO:01001437
name: mining
def: "A planned environmental usage process during which a non-renewable resource such as petroleum, natural gas, or water is extracted from an ecosystem." [https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf, https://en.wikipedia.org/wiki/Land_use, https://en.wikipedia.org/wiki/Mining, https://www.eionet.europa.eu/gemet/en/concept/14837]
is_a: ENVO:01001436 ! planned environmental usage process
relationship: BFO:0000051 ENVO:01000785 ! has part material extraction process
relationship: BFO:0000051 ENVO:01001168 ! has part ecosystem fragmentation process

[Term]
id: ENVO:01001439
name: marine mining
def: "A mining process which occurs in a marine ecosystem." []
is_a: ENVO:01001437 ! mining

[Term]
id: ENVO:01001444
name: usage of an environment for transportation
def: "A planned environmental usage process during which an environment facilitates the movement of materials and material objects (persons or goods) from place to place, typically with the assistance of a vehicle." [https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf, https://en.wikipedia.org/wiki/Land_use, https://www.eionet.europa.eu/gemet/en/concept/8641]
is_a: ENVO:01001436 ! planned environmental usage process
relationship: BFO:0000051 ENVO:03000010 ! has part material transport process
relationship: RO:0000057 ENVO:00000010 ! has participant transport feature

[Term]
id: ENVO:01001450
name: usage of an environment for industry
def: "A planned environmental usage process during which an environment supports manufacturing facilities producing commodities that are sold with the expectation of recovering the total cost of production." [https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf, https://en.wikipedia.org/wiki/Land_use, https://www.eionet.europa.eu/gemet/en/concept/4279]
comment: This class includes environments used to support the facilities engaged with a broad variety of manufacturing activities from food and tobacco, to textiles, metals, vehicles, and chemicals.
is_a: ENVO:01001436 ! planned environmental usage process
relationship: RO:0000057 ENVO:00003861 ! has participant industrial building
relationship: RO:0002234 ENVO:00002267 ! has output industrial waste material

[Term]
id: ENVO:01001451
name: usage of an environment for business
def: "A planned environmental usage process during which an environment supports facilities associated with commerce or the earning of a livelihood through means other than manufacturing or the provision of a public service." [https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/11493/144275.pdf, https://en.wikipedia.org/wiki/Land_use, https://www.eionet.europa.eu/gemet/en/concept/1084]
comment: This class includes activities carried out in commercial offices, meeting centres, art studios, recording studios, film sets, warehouses, and distribution centres.
is_a: ENVO:01001436 ! planned environmental usage process

[Term]
id: ENVO:01001476
name: body of liquid
def: "A liquid astronomical body part which is continuous and is delimited by physical discontinuities or non-liquid boundaries." []
is_a: ENVO:01001477 ! liquid astronomical body part

[Term]
id: ENVO:01001477
name: liquid astronomical body part
def: "A part of an astronomical body which is primarily composed of liquid material." []
is_a: ENVO:01001479 ! fluid astronomical body part
is_a: ENVO:01001784 ! compound astronomical body part
intersection_of: ENVO:01001479 ! fluid astronomical body part
intersection_of: RO:0002473 ENVO:01000815 ! composed primarily of liquid environmental material
relationship: RO:0002473 ENVO:01000815 ! composed primarily of liquid environmental material

[Term]
id: ENVO:01001478
name: gaseous astronomical body part
def: "A part of an astronomical body which is primarily composed of gaseous material." []
is_a: ENVO:01001479 ! fluid astronomical body part
is_a: ENVO:01001784 ! compound astronomical body part
intersection_of: ENVO:01001479 ! fluid astronomical body part
intersection_of: RO:0002473 ENVO:01000797 ! composed primarily of gaseous environmental material
relationship: RO:0002473 ENVO:01000797 ! composed primarily of gaseous environmental material

[Term]
id: ENVO:01001479
name: fluid astronomical body part
def: "A part of an astronomical body which is primarily composed of fluid." [https://en.wikipedia.org/wiki/Fluid]
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:01000813 ! astronomical body part
intersection_of: RO:0002473 ENVO:02000140 ! composed primarily of fluid environmental material
relationship: RO:0002473 ENVO:02000140 ! composed primarily of fluid environmental material

[Term]
id: ENVO:01001482
name: tornado
def: "A tornado is an aeroform consisting of at least one rapidly rotating column of air that is in contact with both the surface of an astronomical body and pendant from within or beneath a cumulonimbus or cumulus cloud." [https://en.wikipedia.org/wiki/Tornado]
comment: This class refers to tornados on Earth, but can be used as the basis for a more generalised class for tornados which a composed of gaseous materials other than air.
synonym: "twister" EXACT []
is_a: ENVO:01000755 ! aeroform
relationship: RO:0000086 PATO:0002063 ! has quality columnar
relationship: RO:0002220 ENVO:01000324 ! adjacent to planetary surface
relationship: RO:0002473 ENVO:00002005 ! composed primarily of air

[Term]
id: ENVO:01001483
name: surface of an astronomical body
def: "A surface layer where the solid or liquid material of an astronomical body comes into contact with an atmosphere or outer space." []
comment: a useful class: this can be used to define sub-terrestrial and sub-marine entities
is_a: ENVO:00010504 ! surface layer
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:00010504 ! surface layer
intersection_of: BFO:0000050 ENVO:01000799 ! part of astronomical body

[Term]
id: ENVO:01001486
name: landspout
def: "A tornado which a) is not associated with a mesocyclone and is thus relatively weak and short-lived, b) is centred on a small, smooth condensation funnel which often does not reach the planetary surface, and c) forms a distinctively laminar cloud of dust when it makes contact with the land." [https://en.wikipedia.org/wiki/Tornado]
synonym: "dust-tube tornado" EXACT []
synonym: "fair weather waterspout on land" EXACT []
synonym: "land spout" EXACT []
is_a: ENVO:01001482 ! tornado

[Term]
id: ENVO:01001487
name: waterspout
def: "A tornado which connects a cumulus or cumulonimbus cloud to a body of water, often transporting water from that water body along the spiraling winds constituting  its vortex." [https://en.wikipedia.org/wiki/Tornado]
comment: Wikipedia notes that there is disagreement over whether to classify waterspouts as true tornadoes.
synonym: "water spout" EXACT []
is_a: ENVO:01001482 ! tornado

[Term]
id: ENVO:01001491
name: flattened elevation
def: "An elevation which is flattened across its highest surface." []
is_a: ENVO:00000176 ! elevated landform
intersection_of: ENVO:00000176 ! elevated landform
intersection_of: RO:0000086 PATO:0002254 ! has quality flattened
relationship: RO:0000086 PATO:0002254 ! has quality flattened

[Term]
id: ENVO:01001497
name: carbonate system of ocean water
def: "A system which is composed of carbon-based chemical entities dissolved in or otherwise part of an ocean or sea and the atmosphere adjacent to it, undergoing constant exchange through biogeochemical cycling." []
comment: To measure the state and dynamics of the ocean's carbonate system, at least two of the following qualities must be measured: Dissolved Inorganic Carbon (DIC), Total Alkalinity (TA), Partial pressure of carbon dioxide (pCO2), and pH.
synonym: "carbonate system of the sea" EXACT []
synonym: "marine carbonate system" EXACT []
is_a: RO:0002577 ! system
relationship: BFO:0000051 ENVO:01000267 ! has part atmosphere
relationship: RO:0000056 ENVO:01000631 ! participates in ocean acidification
relationship: RO:0000056 ENVO:02500010 ! participates in carbon cycling

[Term]
id: ENVO:01001501
name: radiation from a manufactured product
def: "An electromagnetic radiation process during which electromagnetic waves or their quanta are emitted from a manufactured product." [https://en.wikipedia.org/wiki/Electromagnetic_radiation, https://en.wikipedia.org/wiki/Solar_irradiance]
synonym: "artificial radiation" EXACT []
is_a: ENVO:01001026 ! electromagnetic radiation
intersection_of: ENVO:01001026 ! electromagnetic radiation
intersection_of: RO:0002608 ENVO:00003074 ! process has causal agent manufactured product
relationship: RO:0002608 ENVO:00003074 ! process has causal agent manufactured product

[Term]
id: ENVO:01001510
name: material congelation process
def: "A material transformation process during which a material's viscosity increase either through a reduction in temperature, through chemical reactions, or other physical effects." [https://en.wikipedia.org/wiki/Congelation]
comment: Sometimes the increase in viscosity is great enough to crystallize or solidify the substance in question. {xref="https://en.wikipedia.org/wiki/Congelation"}
synonym: "congelation" EXACT []
synonym: "congelation process" EXACT []
is_a: ENVO:03000043 ! material transformation process

[Term]
id: ENVO:01001524
name: frozen land
def: "Land which is below the freezing point of water." [https://orcid.org/0000-0003-4808-4736]
comment: Perennially and seasonally frozen ground can vary from being partially to extensively frozen depending on the extent of the phase change. It may be described as hard frozen ground, plastic frozen ground, or dry frozen ground, depending on the pore ice and unfrozen water contents and its compressibility under load. {xref="https://orcid.org/0000-0003-4808-4736"}
synonym: "frozen ground" EXACT []
xref: http://sweetontology.net/realmCryo/FrozenGround
is_a: ENVO:01001785 ! land
intersection_of: ENVO:01001785 ! land
intersection_of: RO:0000086 PATO:0001985 ! has quality frozen
relationship: RO:0000086 PATO:0001985 ! has quality frozen

[Term]
id: ENVO:01001526
name: frozen soil
def: "Soil which is below the freezing point of water." []
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0000086 PATO:0001985 ! has quality frozen
relationship: BFO:0000050 ENVO:01001524 ! part of frozen land
relationship: RO:0000086 PATO:0001985 ! has quality frozen

[Term]
id: ENVO:01001548
name: freezing
def: "A material congelation process during which a liquid turns into a solid when its temperature is lowered below its melting point." [https://en.wikipedia.org/wiki/Freezing]
xref: http://sweetontology.net/procStateChange/Freezing
is_a: ENVO:01001510 ! material congelation process

[Term]
id: ENVO:01001549
name: freezing of water into water ice
def: "A freezing process during which liquid water is transformed into water ice." []
is_a: ENVO:01001548 ! freezing
is_a: ENVO:02500031 ! hydrological process
intersection_of: ENVO:01001548 ! freezing
intersection_of: RO:0002233 ENVO:00002006 ! has input liquid water
intersection_of: RO:0002234 ENVO:01000277 ! has output water ice
relationship: RO:0002233 ENVO:00002006 ! has input liquid water
relationship: RO:0002234 ENVO:01000277 ! has output water ice

[Term]
id: ENVO:01001554
name: surface layer of a water body
def: "A water surface that is part of a water body." []
is_a: ENVO:01001191 ! water surface
is_a: ENVO:01001308 ! hydroform
is_a: ENVO:01001483 ! surface of an astronomical body
intersection_of: ENVO:01001191 ! water surface
intersection_of: BFO:0000050 ENVO:00000063 ! part of water body

[Term]
id: ENVO:01001564
name: rain
def: "An aggregate of raindrops falling to a planetary surface during a precipitation process." []
is_a: BFO:0000027 ! object aggregate
relationship: RO:0000056 ENVO:01000875 ! participates in precipitation process
relationship: RO:0002351 ENVO:01000832 ! has member raindrop

[Term]
id: ENVO:01001565
name: water-based rain
def: "Rain which is composed of water droplets falling to a planetary surface during a rainfall process." []
is_a: ENVO:01001564 ! rain
relationship: RO:0000056 ENVO:01000830 ! participates in water-based rainfall
relationship: RO:0002351 ENVO:01000834 ! has member water raindrop

[Term]
id: ENVO:01001566
name: infrasound
def: "Sound which is lower in frequency than 20 Hertz, or cycles per second." [https://en.wikipedia.org/wiki/Infrasound]
comment: 20 Hertz is the average limit of human hearing.
is_a: ENVO:01001027 ! acoustic radiation

[Term]
id: ENVO:01001581
name: sea surface layer
def: "A surface layer which is part of an ocean or sea." []
comment: At this level, the depth of this layer is ambiguous. Some methods (telemetry) measure only the first few centimeters of the sea or ocean surface. In situ methods often sample the first few meters. Subclasses can be created for such cases.\nSea surface layer is also used to refer to the surfaces of oceans.
is_a: ENVO:01000295 ! marine layer
is_a: ENVO:01001554 ! surface layer of a water body

[Term]
id: ENVO:01001609
name: cryospheric layer
def: "A layer which is part of a cryosphere." []
is_a: ENVO:01000281 ! layer
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:01000281 ! layer
intersection_of: BFO:0000050 ENVO:03000143 ! part of cryosphere
relationship: BFO:0000050 ENVO:03000143 ! part of cryosphere

[Term]
id: ENVO:01001614
name: ice-bearing permafrost
def: "Permafrost which contains inclusions of water-based ice." []
is_a: ENVO:00000134 ! permafrost
intersection_of: ENVO:00000134 ! permafrost
intersection_of: BFO:0000051 ENVO:01000277 ! has part water ice
relationship: BFO:0000051 ENVO:01000277 ! has part water ice

[Term]
id: ENVO:01001617
name: snow accumulation process
def: "A material accumulation process during which the mass of snow on a surface increases." [https://orcid.org/0000-0003-4808-4736]
comment: This term is used both as a process and as an amount of mass added. Semantically speaking these are two distinct concepts (e.g., accumulation results in accumulation_amount of ice or snow gain), though accumulation_amount would more likely be an attribute.\n\nThe scope of this term varies depending on the definition.  Some definitions constrain themselves snow or ice added to glaciers; while others also include ice fields, snow cover, and/or floating ice.  How to resolve this depends on the scope desired.\n\nSome definitions include additional discussion of the the physics involved which would be useful for connecting glacier ontologies to atmospheric, hydrologic, etc. ontologies.  This information should be captured no matter how the inconsistencies above are resolved.
xref: http://sweetontology.net/phenCryo/Accumulation
is_a: ENVO:03000009 ! material accumulation process
is_a: GO:0008150 ! biological_process
relationship: RO:0000057 ENVO:00010504 ! has participant surface layer
relationship: RO:0000057 ENVO:01000406 ! has participant snow
relationship: RO:0002297 ENVO:03000111 ! results in formation of anatomical entity snow mass

[Term]
id: ENVO:01001618
name: ice accumulation process
def: "A material accumulation process during which ice forms in an environmental material or an existing accumulation of ice increases in mass." [https://orcid.org/0000-0003-4808-4736]
xref: http://sweetontology.net/phenCryo/Accumulation
is_a: ENVO:02500031 ! hydrological process
is_a: ENVO:03000009 ! material accumulation process

[Term]
id: ENVO:01001619
name: snow and ice accumulation process
def: "A material accumulation process during which a accumulation of snow and ice forms or increases in mass." [https://orcid.org/0000-0003-4808-4736]
xref: http://sweetontology.net/phenCryo/Accumulation
is_a: ENVO:02500031 ! hydrological process
intersection_of: ENVO:03000009 ! material accumulation process
intersection_of: RO:0002297 ENVO:01001620 ! results in formation of anatomical entity mass of ice and snow
relationship: RO:0002297 ENVO:01001620 ! results in formation of anatomical entity mass of ice and snow

[Term]
id: ENVO:01001620
name: mass of ice and snow
def: "A object which is composed primarily of water-based snow and ice." []
xref: http://sweetontology.net/phenCryo/Accumulation
is_a: ENVO:01000293 ! ice mass
relationship: RO:0002354 ENVO:01001619 ! formed as result of snow and ice accumulation process

[Term]
id: ENVO:01001639
name: formation of a solid aerosol from liquid material in an atmosphere
def: "A process during which microscopic solid particulates are formed from liquid materials in an atmosphere." [https://en.wikipedia.org/wiki/Particulates]
synonym: "formation of solid particles from liquid material in an atmosphere" EXACT []
is_a: ENVO:01001086 ! formation of a solid aerosol in an atmosphere
intersection_of: ENVO:01001086 ! formation of a solid aerosol in an atmosphere
intersection_of: RO:0002233 ENVO:01000815 ! has input liquid environmental material
intersection_of: RO:0002234 ENVO:01001089 ! has output aerosolised solids
relationship: RO:0002233 ENVO:01000815 ! has input liquid environmental material

[Term]
id: ENVO:01001644
name: material primarily composed of biogenic carbonates
xref: Carbonate which is formed as the result of some biological process.
xref: http://vocab.nerc.ac.uk/collection/S23/current/S23C021/
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:01001645
name: gaseous part of an atmosphere
def: "That part of an atmosphere which is composed of gaseous material." []
xref: http://vocab.nerc.ac.uk/collection/S23/current/S23C013/
is_a: ENVO:01001478 ! gaseous astronomical body part
intersection_of: ENVO:01001478 ! gaseous astronomical body part
intersection_of: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: BFO:0000050 ENVO:01000267 ! part of atmosphere

[Term]
id: ENVO:01001646
name: amorphous solid
def: "A solid material which does not have a regularly organised internal structure." []
xref: http://vocab.nerc.ac.uk/collection/S23/current/S23C014/
is_a: ENVO:01000814 ! solid environmental material

[Term]
id: ENVO:01001652
name: atmospheric aerosol
def: "An aerosol that is suspended in an atmosphere." []
xref: http://vocab.nerc.ac.uk/collection/S23/current/S23C005/
is_a: ENVO:00010505 ! aerosol
intersection_of: ENVO:00010505 ! aerosol
intersection_of: BFO:0000050 ENVO:01000267 ! part of atmosphere
relationship: BFO:0000050 ENVO:01000267 ! part of atmosphere

[Term]
id: ENVO:01001654
name: aerosol formation process
def: "A material transformation process during which solid or liquid particles form and are suspended in a mass of air, thus creating an aerosol." []
is_a: ENVO:03000043 ! material transformation process
intersection_of: ENVO:03000043 ! material transformation process
intersection_of: RO:0002234 ENVO:00010505 ! has output aerosol
relationship: BFO:0000051 ENVO:01001366 ! has part aerosolised particle formation process
relationship: RO:0002234 ENVO:00010505 ! has output aerosol

[Term]
id: ENVO:01001673
name: fluid surface layer
def: "A surface layer which is composed primarily of some liquid or gas." []
is_a: ENVO:00010504 ! surface layer
is_a: ENVO:01001677 ! fluid interface layer

[Term]
id: ENVO:01001677
name: fluid interface layer
def: "A surface layer which separates two portions of fluid with respect to either 1) a discontinuity of some fluid property or 2) some derivative of one of these properties in a direction normal to the interface." [http://glossary.ametsoc.org/wiki/Interface]
is_a: ENVO:01001678 ! fluid layer
is_a: ENVO:01001684 ! interface layer

[Term]
id: ENVO:01001678
name: fluid layer
def: "A layer which is composed primarily of some fluid." []
is_a: ENVO:01000281 ! layer

[Term]
id: ENVO:01001682
name: air mass
def: "An object which is composed of a continuous mass of air." []
is_a: ENVO:01001689 ! mass of gas
intersection_of: ENVO:01001689 ! mass of gas
intersection_of: RO:0002473 ENVO:00002005 ! composed primarily of air
relationship: RO:0002473 ENVO:00002005 ! composed primarily of air

[Term]
id: ENVO:01001683
name: gaseous surface layer
def: "A fluid surface layer which is composed primarily of some gaseous material." []
is_a: ENVO:01001673 ! fluid surface layer
intersection_of: ENVO:01001673 ! fluid surface layer
intersection_of: RO:0002473 ENVO:01000797 ! composed primarily of gaseous environmental material
relationship: RO:0002473 ENVO:01000797 ! composed primarily of gaseous environmental material

[Term]
id: ENVO:01001684
name: interface layer
def: "A layer which separates two portions of environmental material which possess 1) differing compositions, 2) a discontinuity of some property, or 3) some derivative of some property in a direction normal to the interface." []
is_a: ENVO:01000281 ! layer

[Term]
id: ENVO:01001686
name: mass of environmental material
def: "An object which is composed primarily of an environmental material" []
comment: This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
is_a: BFO:0000030 ! object
intersection_of: BFO:0000030 ! object
intersection_of: RO:0002473 ENVO:00010483 ! composed primarily of environmental material
relationship: RO:0002473 ENVO:00010483 ! composed primarily of environmental material

[Term]
id: ENVO:01001687
name: mass of solid material
def: "An mass of environmental material which is composed primarily of a solid environmental material" []
comment: This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
is_a: ENVO:01001686 ! mass of environmental material
intersection_of: ENVO:01001686 ! mass of environmental material
intersection_of: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material
relationship: RO:0002473 ENVO:01000814 ! composed primarily of solid environmental material

[Term]
id: ENVO:01001688
name: mass of fluid
def: "An object which is composed primarily of a fluid." []
comment: This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
synonym: "fluid mass" EXACT []
is_a: ENVO:01001686 ! mass of environmental material

[Term]
id: ENVO:01001689
name: mass of gas
def: "An object which is composed primarily of a gas." []
comment: This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
synonym: "gaseous mass" EXACT []
is_a: ENVO:01001688 ! mass of fluid
intersection_of: ENVO:01001688 ! mass of fluid
intersection_of: RO:0002473 ENVO:01000797 ! composed primarily of gaseous environmental material
relationship: RO:0002473 ENVO:01000797 ! composed primarily of gaseous environmental material

[Term]
id: ENVO:01001690
name: mass of liquid
def: "An object which is composed primarily of a liquid." []
comment: This class and its subclasses refer to objects that are discrete accumulations of environmental materials, generally primarily composed of one or a few main material types.
synonym: "liquid mass" EXACT []
is_a: ENVO:01001688 ! mass of fluid
intersection_of: ENVO:01001688 ! mass of fluid
intersection_of: RO:0002473 ENVO:01000815 ! composed primarily of liquid environmental material
relationship: RO:0002473 ENVO:01000815 ! composed primarily of liquid environmental material

[Term]
id: ENVO:01001691
name: mass of compounded environmental materials
def: "An mass of environmental materials which has appreciable quantities of several individual materials, such that the removal of one would convert the mass into a different entity." []
is_a: ENVO:01001686 ! mass of environmental material
intersection_of: ENVO:01001686 ! mass of environmental material
intersection_of: RO:0002473 ENVO:00010483 {minCardinality="2"} ! composed primarily of environmental material

[Term]
id: ENVO:01001747
name: mass fluid flow
def: "An advective transport process during which a fluid moves." []
is_a: ENVO:01001334 ! advective transport process
relationship: RO:0000057 ENVO:02000140 ! has participant fluid environmental material

[Term]
id: ENVO:01001748
name: cyclonic circulation
def: "A mass fluid flow which moves  in the same direction as a planet's rotation, rotating due to a Coriolis effect." [http://glossary.ametsoc.org/wiki/Cyclonic_circulation, https://en.wikipedia.org/wiki/Cyclonic_rotation]
synonym: "cyclonic rotation" EXACT []
is_a: ENVO:01001747 ! mass fluid flow

[Term]
id: ENVO:01001759
name: vibration process
def: "A material transport process during which parts of an elastic material oscillate around their positions of equilibrium." [] {comment="https://www.merriam-webster.com/dictionary/vibration"}
synonym: "vibration" EXACT []
is_a: ENVO:03000010 ! material transport process

[Term]
id: ENVO:01001767
name: structural collapse process
def: "A process during which the ability of a material entity to maintain its internal organisation fails, resulting in deformation and a breakdown of that organisation." [https://en.wikipedia.org/wiki/Structural_failure]
comment: This is a very general concept, and should likely be elevated to OBO Core rather than held in ENVO.
is_a: ENVO:01001852 ! energy transfer process

[Term]
id: ENVO:01001776
name: subsurface zone of an astronomical body
def: "An environmental zone which includes those regions of an astronomical body which are not exposed to its atmosphere or space." []
is_a: ENVO:01000408 ! environmental zone
is_a: ENVO:01000813 ! astronomical body part

[Term]
id: ENVO:01001780
name: desert ecosystem
def: "An ecosystem in which the composition, structure, and function of resident ecological assemblages are primarily determined by a desert." []
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01001110 ! ecosystem
intersection_of: ENVO:01001110 ! ecosystem
intersection_of: RO:0002507 ENVO:01001357 ! determined by desert
relationship: RO:0002507 ENVO:01001357 ! determined by desert

[Term]
id: ENVO:01001781
name: part of a landmass
def: "A solid astronomical body part which is part of the landmass of that body." []
is_a: ENVO:00000191 ! solid astronomical body part
intersection_of: ENVO:00000191 ! solid astronomical body part
intersection_of: BFO:0000050 ENVO:01000635 ! part of planetary landmass
relationship: BFO:0000050 ENVO:01000635 ! part of planetary landmass

[Term]
id: ENVO:01001782
name: landmass
is_a: ENVO:01001785 ! land

[Term]
id: ENVO:01001784
name: compound astronomical body part
def: "A part of an astronomical body which is composed of a continuous medium bearing liquid, gaseous, and solid material in variable quantities." [https://en.wikipedia.org/wiki/Landform]
is_a: ENVO:01000813 ! astronomical body part

[Term]
id: ENVO:01001785
name: land
def: "A surface layer of an astronomical body which is primarily composed of solid material and is not covered by oceans or other bodies of water." [https://en.wiktionary.org/wiki/land]
is_a: ENVO:00000191 ! solid astronomical body part
is_a: ENVO:01001311 ! solid surface layer
is_a: ENVO:01001483 ! surface of an astronomical body

[Term]
id: ENVO:01001787
name: aquatic ecosystem
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01001110 ! ecosystem
intersection_of: ENVO:01001110 ! ecosystem
intersection_of: RO:0002507 ENVO:00000063 ! determined by water body
relationship: RO:0002507 ENVO:00000063 ! determined by water body

[Term]
id: ENVO:01001788
name: marine ecosystem
is_a: ENVO:01000320 ! marine environment
is_a: ENVO:01001787 ! aquatic ecosystem
intersection_of: ENVO:01001787 ! aquatic ecosystem
intersection_of: RO:0002507 ENVO:00001999 ! determined by marine water body

[Term]
id: ENVO:01001789
name: freshwater ecosystem
is_a: ENVO:01001787 ! aquatic ecosystem
intersection_of: ENVO:01001787 ! aquatic ecosystem
intersection_of: RO:0002507 ENVO:01001320 ! determined by fresh water body
relationship: RO:0002507 ENVO:01001320 ! determined by fresh water body

[Term]
id: ENVO:01001790
name: terrestrial ecosystem
def: "An ecosystem which primarily occurs on land." []
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:01001110 ! ecosystem
intersection_of: ENVO:01001110 ! ecosystem
intersection_of: RO:0002507 ENVO:01001785 ! determined by land
relationship: RO:0002507 ENVO:01001785 ! determined by land

[Term]
id: ENVO:01001795
name: ecosystem process
def: "An environmental process either driven by or primarily impacting the parts or emergent properties of an ecosystem." []
is_a: ENVO:02500000 ! environmental system process
intersection_of: ENVO:02500000 ! environmental system process
intersection_of: RO:0002608 ENVO:01001110 ! process has causal agent ecosystem
relationship: RO:0002608 ENVO:01001110 ! process has causal agent ecosystem

[Term]
id: ENVO:01001813
name: construction
def: "A material entity which has been assembled through the intentional, instinctual, or deliberately programmed efforts of an organism or machine." []
is_a: BFO:0000040 ! material entity

[Term]
id: ENVO:01001814
name: organic object
def: "An object which is formed as a result of one or more biological processes and is composed primarily of organic material." []
is_a: ENVO:01001686 ! mass of environmental material
intersection_of: BFO:0000030 ! object
intersection_of: RO:0002354 GO:0008150 ! formed as result of biological_process
intersection_of: RO:0002473 ENVO:01000155 ! composed primarily of organic material
relationship: RO:0002354 GO:0008150 ! formed as result of biological_process
relationship: RO:0002473 ENVO:01000155 ! composed primarily of organic material

[Term]
id: ENVO:01001824
name: ecological succession
def: "An ecosystem process during which the species composition of an ecosystem gradually changes as species which are more adapted to the prevailing conditions in the ecosystem replace those which are less adapted." [https://en.wikipedia.org/wiki/Ecological_succession]
is_a: ENVO:01001795 ! ecosystem process

[Term]
id: ENVO:01001827
name: climactic ecological succession
def: "An ecological succession process during which 1) organisms in ecological communities possess high adaptation to the conditions in the ecosystem, 2) participant communities largely fill available niches, 3) individual organisms are typically replaced by others of the same species, 4) a near equilibrium is maintained between gross primary production and total respiration and across biogeochemical cycles." [https://en.wikipedia.org/wiki/Ecological_succession]
is_a: ENVO:01001824 ! ecological succession

[Term]
id: ENVO:01001828
name: anthropised ecosystem
def: "An ecosystem which is formed as a result of human activity or impact." []
is_a: ENVO:01000313 ! anthropogenic environment
is_a: ENVO:01001110 ! ecosystem
intersection_of: ENVO:01001110 ! ecosystem
intersection_of: RO:0002354 ENVO:01000952 ! formed as result of anthropisation

[Term]
id: ENVO:01001829
name: human settlement
def: "An anthropised ecosystem which is determined by the presence of humans and their constructions." []
is_a: ENVO:01000813 ! astronomical body part
is_a: ENVO:01001002 ! animal-associated environment
is_a: ENVO:01001055 ! environment associated with an animal part or small animal
is_a: ENVO:01001828 ! anthropised ecosystem
intersection_of: ENVO:01001828 ! anthropised ecosystem
intersection_of: RO:0002507 ENVO:00000070 ! determined by human construction
intersection_of: RO:0002507 NCBITaxon:9606 ! determined by Homo sapiens
relationship: RO:0002507 ENVO:00000070 ! determined by human construction
relationship: RO:0002507 NCBITaxon:9606 ! determined by Homo sapiens

[Term]
id: ENVO:01001838
name: arid biome
def: "A biome which is subject to arid environmental conditions." []
is_a: ENVO:00000428 ! biome
intersection_of: ENVO:00000428 ! biome
intersection_of: RO:0000086 ENVO:01000230 ! has quality arid
relationship: RO:0000086 ENVO:01000230 ! has quality arid

[Term]
id: ENVO:01001852
name: energy transfer process
def: "A process during which one entity loses energy to another entity." []
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:01001856
name: liquid accumulation process
def: "A material accumulation process during which the volume of liquid entity increases." []
is_a: ENVO:03000009 ! material accumulation process
intersection_of: ENVO:03000009 ! material accumulation process
intersection_of: RO:0000057 ENVO:01000815 ! has participant liquid environmental material
relationship: RO:0000057 ENVO:01000815 ! has participant liquid environmental material

[Term]
id: ENVO:01001861
name: shortwave radiation
def: "An electromagnetic radiation process during which radiant energy with wavelengths in the visible, near-ultraviolet, or near-infrared spectra is realised." [https://en.wikipedia.org/wiki/Shortwave_radiation]
comment: There is no standard cut-off for the near-infrared range; therefore, the shortwave radiation range is also variously defined. It may be broadly defined to include all radiation with a wavelength of 0.1 micrometers and 5.0 micrometers or narrowly defined so as to include only radiation between 0.2 micrometers and 3.0 micrometers. {xref="Shortwave:radiation"}
synonym: "short-wave radiation" EXACT []
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:01001862
name: Solar radiation
def: "Stellar radiation emitted from Sol." []

[Term]
id: ENVO:01001864
name: photosynthetically active radiation
def: "Electromagnetic radidation which involves radiant energy in a spectral range (wave band) between 400 to 700 nanometers, that photosynthetic organisms are able to use in the process of photosynthesis." [https://en.wikipedia.org/wiki/Photosynthetically_active_radiation]
comment: Many definitions specify that this is Solar radiation, but consistency is lacking.
synonym: "PAR" EXACT []
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:01001865
name: concentration of carbon dioxide in an atmosphere
def: "The concentration of carbon dioxide when measured in air that is part of an atmosphere." []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:01001884
name: surface landform
def: "A landform which occurs on the surface of an astronomical body." []
comment: The usage of "surface" here aligns with that of planetary surface: in contact with the atmosphere or space. The extent of the "surface" can vary. For rocky planets like Earth, astrogeologists consider the crust as the surface.
is_a: ENVO:01001886 ! landform

[Term]
id: ENVO:01001886
name: landform
def: "A solid astronomical body part which has been formed from and is composed primarily of the matter of that astronomical body." [https://en.wikipedia.org/wiki/Landform]
comment: Landforms may be natural or anthropogenic. This term has often has loose usage when referencing entities which are either subterranean or submerged below water bodies. In some cases, oceans themselves are considered landforms. Here, we have provided subclasses to resolve this ambiguity, but place oceans and other water bodies elsewhere.In later revisions, this hiearchy is likely to be reordered based on the formation processes of the entities within it.
is_a: ENVO:00000191 ! solid astronomical body part

[Term]
id: ENVO:01003000
name: spacecraft
def: "A vehicle designed to fly in outer space." [https://en.wikipedia.org/wiki/Spacecraft]
is_a: ENVO:01000604 ! vehicle

[Term]
id: ENVO:01003001
name: water-holding capacity
def: "A disposition of a material entity which is realised when it is saturated with liquid water." []
is_a: BFO:0000016 ! disposition
relationship: RO:0000052 BFO:0000040 ! characteristic of material entity

[Term]
id: ENVO:01003002
name: particle
def: "A mass of solid material which is either 1) a minute fragment of a larger mass or 2) one of a collection of small masses composing an aggregate." [https://en.wiktionary.org/wiki/particle]
is_a: ENVO:01001687 ! mass of solid material
relationship: BFO:0000050 ENVO:01000060 ! part of particulate environmental material

[Term]
id: ENVO:01003003
name: particle of clay
def: "A particle which 1) is composed primarily of hydrous aluminium phyllosilicate minerals, in turn composed of aluminium and silicon ions bonded into tiny, thin plates by interconnecting oxygen and hydroxide ions, and 2) is or was part of a portion of clay." [https://en.wikipedia.org/wiki/Clay#Properties]
comment: The distinction between silt and clay varies by discipline. Geologists and soil scientists usually consider the separation to occur at a particle size of 2 μm (clays being finer than silts), sedimentologists often use 4–5 μm, and colloid chemists use 1 μm. Geotechnical engineers distinguish between silts and clays based on the plasticity properties of the soil, as measured by the soils' Atterberg limits. ISO 14688 grades clay particles as being smaller than 2 μm and silt particles as being larger. Mixtures of sand, silt and less than 40% clay are called loam. {xref="Properties"}
synonym: "clay particle" EXACT []
is_a: ENVO:01003002 ! particle

[Term]
id: ENVO:01003010
name: convective transport process
def: "A material transport process which arises spontaneously due to physical heterogeneities in a portion of a material and forces which act throughout its volume." [https://en.wikipedia.org/wiki/Convection]
comment: Most commonly, convective flows are generated by heterogeneities in density or the effects of gravity. When the cause of the convection is unspecified, convection due to the effects of thermal expansion and buoyancy can be assumed. Convection frequently occurs in fluids, but may also take place in soft solids or mixtures where particles can flow. {xref="https://en.wikipedia.org/wiki/Convection"}
is_a: ENVO:03000010 ! material transport process
intersection_of: ENVO:03000010 ! material transport process
intersection_of: RO:0000053 ENVO:01003011 ! has characteristic convective
relationship: RO:0000053 ENVO:01003011 ! has characteristic convective

[Term]
id: ENVO:01003011
name: convective
def: "A physical quality of a process which is characteristic of processes that transport material within a volume due to the combined effects of material property heterogeneity and body forces across that volume." [https://en.wikipedia.org/wiki/Convection]
is_a: PATO:0002062 ! physical quality of a process

[Term]
id: ENVO:01003012
name: advective
def: "A physical quality of a process which is characteristic of process that transport material without, themselves, changing the qualities of those materials or the processes that are unfolding within them." [https://en.wikipedia.org/wiki/Advection]
is_a: PATO:0002062 ! physical quality of a process

[Term]
id: ENVO:01003013
name: material diffusion process
def: "A material transport process during which material moves from a region of higher concentration to a region of lower concentration." [https://en.wikipedia.org/wiki/Diffusion]
comment: Diffusion is also applied to the movement of energy, thus the more specific label. This class will be repositioned (but with the core of its definition intact) if we include other forms of diffusion in ENVO.
is_a: ENVO:03000010 ! material transport process

[Term]
id: ENVO:01003014
name: irradiation
def: "An energy transfer process during which a material entity receives energy through radiation." [https://en.wikipedia.org/wiki/Irradiation]
comment: The term irradiation usually - but not always - excludes the exposure to non-ionizing radiation, such as infrared, visible light, microwaves from cellular phones or electromagnetic waves emitted by radio and TV receivers and power supplies. Please use the subclasses of this term for precision. {xref="https://en.wikipedia.org/wiki/Irradiation"}
is_a: ENVO:01001852 ! energy transfer process
relationship: RO:0000057 ENVO:00010504 ! has participant surface layer
relationship: RO:0002427 ENVO:01001023 ! causally downstream of or within radiation

[Term]
id: ENVO:01003015
name: irradiation by ionizing radiation
def: "Irradiation during which a material entity receives energy through ionizing radiation." []
comment: Usage of this term typically excludes low or background levels of exposure, and is often linked with a purpose such as sterilisation. This class does not differentiate on such a basis, and subclasses - e.g. "irradiation by ionizing radiation for sterilization" can be created for specific applications if required. {xref="https://en.wikipedia.org/wiki/Irradiation"}
synonym: "irradiation by ionising radiation" EXACT []
is_a: ENVO:01003014 ! irradiation
relationship: BFO:0000051 ENVO:21001219 ! has part ionizing radiation

[Term]
id: ENVO:01003016
name: irradiation by non-ionizing radiation
def: "Irradiation during which a material entity receives energy through non-ionizing radiation." []
comment: Note that some forms of ultraviolet radiation can be ionising, thus it is not included in the logical axioms of this class. {xref="https://en.wikipedia.org/wiki/Irradiation"}
synonym: "irradiation by non-ionising radiation" EXACT []
is_a: ENVO:01003014 ! irradiation

[Term]
id: ENVO:01003017
name: irradiation by photosynthetically active radiation
def: "Irradiation during which a material entity receives energy through photosynthetically active radiation." []
is_a: ENVO:01003016 ! irradiation by non-ionizing radiation
relationship: BFO:0000051 ENVO:01001864 ! has part photosynthetically active radiation

[Term]
id: ENVO:02000019
name: bodily fluid material
def: "An organic material which is primarily composed of some natural bodily fluid or secretion such as blood, semen, saliva, blood plasma, intracellular and interstitial fluids." [https://en.wikipedia.org/wiki/Body_fluid, URL:http\://medical-dictionary.thefreedictionary.com/bodily+fluid]
comment: ENVO bodily fluid classes differ from UBERON's treatment of bodily fluids. UBERON refers to the substance itself ("S"). We assert that UBERON's classes are the primary compositional component of the terms in ENVO ("S material"). Use of the ENVO terms is typically recommended when you wish to indicate that there may be other materials intermixed with S.
xref: https://en.wikipedia.org/wiki/Bodily_fluid
is_a: ENVO:01000155 ! organic material
relationship: RO:0002473 UBERON:0002297 ! composed primarily of cerumen

[Term]
id: ENVO:02000020
name: blood material
def: "A bodily fluid material which is composed primarily of blood, a bodily fluid composed of blood plasma and blood cells suspended within the plasma that circulates around the organism's body. Blood performs may important functions including the supplying of oxygen and nutrients, removal of waste, circulation of white blood cells, detection of antibodes, coagulation, transportation of antibodies and the regulation of pH and body temperature." [https://en.wikipedia.org/wiki/Blood, https://en.wikipedia.org/wiki/Body_fluid]
comment: ENVO bodily fluid classes differ from UBERON's treatment of bodily fluids. UBERON refers to the substance itself ("S"). We assert that UBERON's classes are the primary compositional component of the terms in ENVO ("S material"). Use of the ENVO terms is typically recommended when you wish to indicate that there may be other materials intermixed with S.
is_a: ENVO:02000019 ! bodily fluid material
is_a: ENVO:02000140 ! fluid environmental material
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002473 UBERON:0000178 ! composed primarily of blood

[Term]
id: ENVO:02000021
name: amniotic fluid material
def: "A bodily fluid material which is composed primarily of amniotic fluid, a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided." [URL:http\://en.wikipedia.org/wiki/Amniotic_fluid]
comment: ENVO bodily fluid classes differ from UBERON's treatment of bodily fluids. UBERON refers to the substance itself ("S"). We assert that UBERON's classes are the primary compositional component of the terms in ENVO ("S material"). Use of the ENVO terms is typically recommended when you wish to indicate that there may be other materials intermixed with S.
is_a: ENVO:02000019 ! bodily fluid material
relationship: RO:0002473 UBERON:0000173 ! composed primarily of amniotic fluid

[Term]
id: ENVO:02000022
name: excreta material
def: "A bodily fluid material which is composed primarily of excreta, bodily fluids consisting of matter which contains the waste products of biological processes, including urine or feces, discharged from an organism's body." [URL:http\://medical-dictionary.thefreedictionary.com/excreta]
comment: ENVO bodily fluid classes differ from UBERON's treatment of bodily fluids. UBERON refers to the substance itself ("S"). We assert that UBERON's classes are the primary compositional component of the terms in ENVO ("S material"). Use of the ENVO terms is typically recommended when you wish to indicate that there may be other materials intermixed with S.
is_a: ENVO:00002264 ! waste material
is_a: ENVO:02000019 ! bodily fluid material
relationship: RO:0002473 UBERON:0000174 ! composed primarily of excreta

[Term]
id: ENVO:02000023
name: bile material
def: "A bodily fluid material which is composed primarily of bile, a bodily fluid consisting of a bitter, yellow or green alkaline fluid secreted by hepatocytes from the liver of most vertebrates. In many species, bile is stored in the gallbladder between meals and upon eating is discharged into the duodenum where the bile aids the process of digestion of lipids." [https://en.wikipedia.org/wiki/Bile]
comment: ENVO bodily fluid classes differ from UBERON's treatment of bodily fluids. UBERON refers to the substance itself ("S"). We assert that UBERON's classes are the primary compositional component of the terms in ENVO ("S material"). Use of the ENVO terms is typically recommended when you wish to indicate that there may be other materials intermixed with S.
is_a: ENVO:02000019 ! bodily fluid material
relationship: RO:0002473 UBERON:0001970 ! composed primarily of bile

[Term]
id: ENVO:02000049
name: coastal water body
def: "Coastal water is a marine water body bordering a coast." [https://en.wikipedia.org/wiki/Coastal]
is_a: ENVO:00001999 ! marine water body
intersection_of: ENVO:00001999 ! marine water body
intersection_of: RO:0002220 ENVO:00000303 ! adjacent to sea coast
relationship: RO:0002220 ENVO:00000303 ! adjacent to sea coast

[Term]
id: ENVO:02000090
name: ash
def: "An environmental material that is the non-aqueous, non-gaseous residues that remain after something is burned." [https://en.wikipedia.org/wiki/Ash]
is_a: ENVO:01000814 ! solid environmental material
relationship: RO:0002353 ENVO:01000839 ! output of combustion process

[Term]
id: ENVO:02000091
name: coal
def: "A combustible black or brownish-black sedimentary rock usually occurring in rock strata in layers or veins called coal beds or coal seams." [https://en.wikipedia.org/wiki/Coal]
is_a: ENVO:00002016 ! sedimentary rock
relationship: RO:0000086 PATO:0015022 ! has quality increased combustibility
relationship: RO:0000087 CHEBI:35230 ! has role fossil fuel

[Term]
id: ENVO:02000092
name: iron mine
is_a: ENVO:00000076 ! mine

[Term]
id: ENVO:02000093
name: uranium mine
xref: Uranium:mining
is_a: ENVO:00000076 ! mine

[Term]
id: ENVO:02000094
name: ore
def: "a type of rock that contains sufficient minerals with important elements including metals that can be economically extracted from the rock." []
xref: https://en.wikipedia.org/wiki/Ore
is_a: ENVO:00001995 ! rock

[Term]
id: ENVO:02000095
name: uranium ore
def: "Ore which contains uranium." []
comment: The primary uranium ore mineral is uraninite
is_a: ENVO:02000094 ! ore
intersection_of: ENVO:02000094 ! ore
intersection_of: BFO:0000051 CHEBI:33499 ! has part uranium molecular entity
relationship: BFO:0000051 CHEBI:33499 ! has part uranium molecular entity

[Term]
id: ENVO:02000096
name: iron ore
is_a: ENVO:02000094 ! ore
intersection_of: ENVO:02000094 ! ore
intersection_of: BFO:0000051 CHEBI:24873 ! has part iron molecular entity
relationship: BFO:0000051 CHEBI:24873 ! has part iron molecular entity

[Term]
id: ENVO:02000097
name: gold ore
is_a: ENVO:02000094 ! ore
intersection_of: ENVO:02000094 ! ore
intersection_of: BFO:0000051 CHEBI:33969 ! has part gold molecular entity
relationship: BFO:0000051 CHEBI:33969 ! has part gold molecular entity

[Term]
id: ENVO:02000098
name: platinum ore
is_a: ENVO:02000094 ! ore
intersection_of: ENVO:02000094 ! ore
intersection_of: BFO:0000051 CHEBI:33749 ! has part platinum molecular entity
relationship: BFO:0000051 CHEBI:33749 ! has part platinum molecular entity

[Term]
id: ENVO:02000099
name: coal dust
def: "Dust which is derived from coal." []
is_a: ENVO:00002008 ! dust
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0001000 ENVO:02000091 ! derives from coal
relationship: RO:0001000 ENVO:02000091 ! derives from coal

[Term]
id: ENVO:02000100
name: mineral dust
def: "Dust which is derived from mineral material." []
is_a: ENVO:00002008 ! dust
is_a: ENVO:01000256 ! mineral material
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0001000 ENVO:01000256 ! derives from mineral material
relationship: RO:0001000 ENVO:01000256 ! derives from mineral material

[Term]
id: ENVO:02000101
name: fibrous dust
def: "Dust which is composed of fibrous material." []
is_a: ENVO:00002008 ! dust

[Term]
id: ENVO:02000102
name: fibrous glass dust
is_a: ENVO:02000101 ! fibrous dust

[Term]
id: ENVO:02000103
name: metallic dust
def: "Dust which is composed primarily of some metallic material." []
is_a: ENVO:00002008 ! dust
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0001000 ENVO:01001069 ! derives from metallic material
relationship: RO:0001000 ENVO:01001069 ! derives from metallic material
relationship: RO:0002473 ENVO:01001069 ! composed primarily of metallic material

[Term]
id: ENVO:02000104
name: cement dust
is_a: ENVO:00002008 ! dust
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0001000 ENVO:01000462 ! derives from masonry cement
relationship: RO:0001000 ENVO:01000462 ! derives from masonry cement

[Term]
id: ENVO:02000105
name: clay dust
def: "Dust which is derived from clay material." []
is_a: ENVO:00002008 ! dust
intersection_of: ENVO:00002008 ! dust
intersection_of: RO:0001000 ENVO:00002982 ! derives from clay
relationship: RO:0001000 ENVO:00002982 ! derives from clay

[Term]
id: ENVO:02000106
name: asbestos dust
comment: Dust which is derived from asbestos
is_a: ENVO:02000101 ! fibrous dust
intersection_of: ENVO:02000101 ! fibrous dust
intersection_of: RO:0001000 CHEBI:46661 ! derives from asbestos
relationship: RO:0001000 CHEBI:46661 ! derives from asbestos

[Term]
id: ENVO:02000107
name: grain dust
def: "Dust that comes from grain and all the other substances associated with its cultivation & harvesting." [http://www.cdc.gov/niosh/npg/npgd0305.html]
is_a: ENVO:02000109 ! dust from plant parts

[Term]
id: ENVO:02000108
name: cotton dust
is_a: ENVO:02000109 ! dust from plant parts

[Term]
id: ENVO:02000109
name: dust from plant parts
is_a: ENVO:00002008 ! dust

[Term]
id: ENVO:02000111
name: copper ore
is_a: ENVO:02000094 ! ore
intersection_of: ENVO:02000094 ! ore
intersection_of: BFO:0000051 CHEBI:23377 ! has part copper molecular entity
relationship: BFO:0000051 CHEBI:23377 ! has part copper molecular entity

[Term]
id: ENVO:02000112
name: fume
def: "A gas, smoke, or vapor that smells strongly or is dangerous to inhale." []
is_a: ENVO:01000797 ! gaseous environmental material

[Term]
id: ENVO:02000113
name: welding fume
is_a: ENVO:02000112 ! fume

[Term]
id: ENVO:02000115
name: vanadium fume
def: "Respirable vapor of vanadium." [https://www.wikidata.org/wiki/Q20963940]
is_a: ENVO:02000112 ! fume
intersection_of: ENVO:02000112 ! fume
intersection_of: BFO:0000051 CHEBI:27275 ! has part vanadium molecular entity
relationship: BFO:0000051 CHEBI:27275 ! has part vanadium molecular entity

[Term]
id: ENVO:02000120
name: zinc chloride fume
is_a: ENVO:02000112 ! fume
intersection_of: ENVO:02000112 ! fume
intersection_of: BFO:0000051 CHEBI:49976 ! has part zinc dichloride
relationship: BFO:0000051 CHEBI:49976 ! has part zinc dichloride

[Term]
id: ENVO:02000123
name: paint
def: "Any liquid, liquefiable, or mastic composition that, after application to a substrate in a thin layer, converts to a solid film. It is most commonly used to protect, color, or provide texture to objects." [https://en.wikipedia.org/wiki/Paint]
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:01000815 ! liquid environmental material

[Term]
id: ENVO:02000124
name: lead paint
def: "Paint that contains lead." [https://en.wikipedia.org/wiki/Lead_paint]
is_a: ENVO:02000123 ! paint
intersection_of: ENVO:02000123 ! paint
intersection_of: BFO:0000051 CHEBI:33585 ! has part lead molecular entity
relationship: BFO:0000051 CHEBI:33585 ! has part lead molecular entity

[Term]
id: ENVO:02000126
name: wood ash
def: "the residue powder that is derived from the combustion of wood." [https://en.wikipedia.org/wiki/Wood_ash]
is_a: ENVO:02000090 ! ash
intersection_of: ENVO:02000090 ! ash
intersection_of: RO:0001000 ENVO:00002040 ! derives from wood
relationship: RO:0001000 ENVO:00002040 ! derives from wood

[Term]
id: ENVO:02000127
name: coal ash
def: "Ash that is produced from the burning of coal." [https://www.epa.gov/coalash/coal-ash-basics]
synonym: "coal combustion residuals" EXACT [https://www.epa.gov/coalash/coal-ash-basics]
is_a: ENVO:02000090 ! ash
intersection_of: ENVO:02000090 ! ash
intersection_of: RO:0001000 ENVO:02000091 ! derives from coal
relationship: RO:0001000 ENVO:02000091 ! derives from coal

[Term]
id: ENVO:02000128
name: fly ash
def: "A very fine, powdery material composed mostly of silica made from the burning of finely ground coal in a boiler." [https://www.epa.gov/coalash/coal-ash-basics]
is_a: ENVO:02000127 ! coal ash

[Term]
id: ENVO:02000133
name: nuclear reactor
def: "A human construction which is used to initiate and control a fission nuclear chain reaction or nuclear fusion reactions." [https://en.wikipedia.org/wiki/Nuclear_reactor]
is_a: ENVO:00000070 ! human construction

[Term]
id: ENVO:02000137
name: nuclear power reactor
def: "A nuclear reactor which is used as a source of power." [https://en.wikipedia.org/wiki/Nuclear_reactor]
synonym: "power reactor" EXACT []
is_a: ENVO:02000133 ! nuclear reactor

[Term]
id: ENVO:02000140
name: fluid environmental material
def: "An environmental material which is unable to resist shear forces and continuously deforms when subject to them." [https://en.wikipedia.org/wiki/Fluid, https://github.com/EnvironmentOntology/envo/issues/940]
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:02500000
name: environmental system process
def: "A process in which includes the components of an environmental system as participants." []
comment: This is a convenience class for organisation and should not be used for annotation.
is_a: BFO:0000015 ! process

[Term]
id: ENVO:02500001
name: desertification
def: "A type of land degradation in which terrestrial ecosystem becomes increasingly dry, typically losing its bodies of water as well as vegetation and wildlife." [https://en.wikipedia.org/wiki/Desertification]
is_a: ENVO:02500005 ! land degradation
intersection_of: ENVO:02500005 ! land degradation
intersection_of: RO:0002234 ENVO:00000097 ! has output desert area
relationship: RO:0002234 ENVO:00000097 ! has output desert area

[Term]
id: ENVO:02500002
name: flooding
def: "A general and temporary condition of partial or complete inundation of normally dry land areas from the overflow of inland and/or tidal waters, and/or the unusual and rapid accumulation or runoff of surface waters from any source. A great flow along a watercourse or a flow causing inundation of lands not normally covered by water." [GEMET: http\://www.eionet.europa.eu/gemet/concept/3301]
is_a: ENVO:01000982 ! water flow process
relationship: RO:0000057 ENVO:00000063 ! has participant water body
relationship: RO:0000057 ENVO:01000635 ! has participant planetary landmass

[Term]
id: ENVO:02500003
name: atmospheric process
def: "A process which occurs within an atmosphere." []
comment: This class will be populated by inference and is primarily organisational.
is_a: ENVO:02500000 ! environmental system process
intersection_of: ENVO:02500000 ! environmental system process
intersection_of: BFO:0000066 ENVO:01000267 ! occurs in atmosphere
relationship: BFO:0000066 ENVO:01000267 ! occurs in atmosphere

[Term]
id: ENVO:02500004
name: greenhouse effect
def: "A process by which thermal radiation from a planetary surface is absorbed by atmospheric greenhouse gases, and is re-radiated in all directions. Since part of this re-radiation is back towards the surface and the lower atmosphere, it results in an elevation of the average surface temperature above what it would be in the absence of the gases." [https://en.wikipedia.org/wiki/Greenhouse_effect]
is_a: ENVO:02500003 ! atmospheric process

[Term]
id: ENVO:02500005
name: land degradation
def: "A process which diminishes the functioning of an ecosystem located on land." [http://www.who.int/globalchange/ecosystems/desert/en/, https://en.wikipedia.org/wiki/Land_degradation]
comment: This could include, for example, reducing soil health, pollinator activity, or an ecosystem's ability  to sequester carbon.
is_a: ENVO:01001795 ! ecosystem process
relationship: BFO:0000050 ENVO:01000743 ! part of land consumption process
relationship: RO:0000057 ENVO:00000446 ! has participant terrestrial biome
relationship: RO:0000057 ENVO:01000635 ! has participant planetary landmass

[Term]
id: ENVO:02500009
name: biogeochemical cycling
def: "A biogeochemical process during which one or more chemical compounds are sequentially converted into a series of related compounds in a regularly repeating, periodic fashion." []
is_a: ENVO:02500030 ! biogeochemical process

[Term]
id: ENVO:02500010
name: carbon cycling
def: "A biogeochemical cycle which has carbon-bearing chemical entities as participants." []
is_a: ENVO:02500009 ! biogeochemical cycling
intersection_of: ENVO:02500009 ! biogeochemical cycling
intersection_of: RO:0002233 CHEBI:27594 ! has input carbon atom
relationship: RO:0002233 CHEBI:27594 ! has input carbon atom

[Term]
id: ENVO:02500012
name: deforestation
def: "An ecosystem process during which the flora and fauna belonging to a forest are removed or destroyed." [http://www.eionet.europa.eu/gemet/en/concept/2036]
is_a: ENVO:01001795 ! ecosystem process

[Term]
id: ENVO:02500014
name: forest process
comment: To be populated through inference. Do not use for annotation.
is_a: ENVO:01001795 ! ecosystem process
intersection_of: ENVO:01001795 ! ecosystem process
intersection_of: RO:0000057 ENVO:00000111 ! has participant forested area
relationship: RO:0000057 ENVO:00000111 ! has participant forested area

[Term]
id: ENVO:02500018
name: algal bloom process
def: "A process during which the populations in a community of algae in a marine or freshwater ecosystem undergo rapid growth, resulting in high concentrations of algal cells that occur only periodically and briefly in that ecosystem, relative to their concentrations through the majority of the planetary orbital period." [https://en.wikipedia.org/wiki/Algal_bloom]
comment: This class is under development. Note that cyanobacterial blooms are often confused with algal blooms. There is no globally recognised threshold beyond which community density enters a bloom state. {xref="https://en.wikipedia.org/wiki/Algal_bloom"}
is_a: ENVO:01001795 ! ecosystem process
relationship: BFO:0000066 ENVO:01000317 ! occurs in aquatic environment
relationship: RO:0000057 ENVO:2000004 ! has participant algal bloom

[Term]
id: ENVO:02500022
name: algal bloom process phase
is_a: ENVO:01001795 ! ecosystem process
relationship: BFO:0000050 ENVO:02500018 ! part of algal bloom process

[Term]
id: ENVO:02500024
name: accumulation of toxins from algal bloom process
comment: TODO; add axioms pointing to GO organismal process; Add axioms pointing to toxin role
is_a: ENVO:02500022 ! algal bloom process phase

[Term]
id: ENVO:02500025
name: degradation of toxins from algal bloom process
is_a: ENVO:02500022 ! algal bloom process phase

[Term]
id: ENVO:02500026
name: anthropogenic modulatory intervention process
def: "A process during which humans apply technology to alter the magnitude, duration, rate, or impact of an environmental process." []
comment: Relabel the obo foundry unique label to be generic process

[Term]
id: ENVO:02500027
name: anthropogenic environmental process
def: "An environmental process which is driven by the action of humans." []
is_a: ENVO:02500000 ! environmental system process
intersection_of: ENVO:02500000 ! environmental system process
intersection_of: RO:0002608 NCBITaxon:9606 ! process has causal agent Homo sapiens
relationship: RO:0002608 NCBITaxon:9606 ! process has causal agent Homo sapiens

[Term]
id: ENVO:02500030
name: biogeochemical process
def: "A process during which chemicals that are involved in natural ecosystem processes are transported or transformed, and which impact the activity of biological entities" [https://en.wikipedia.org/wiki/Biogeochemistry]
is_a: ENVO:02500000 ! environmental system process
relationship: BFO:0000051 GO:0008150 ! has part biological_process
relationship: RO:0000057 CHEBI:24431 ! has participant chemical entity
relationship: RO:0000057 ENVO:01000951 ! has participant natural environment

[Term]
id: ENVO:02500031
name: hydrological process
def: "An environmental process which has water - in any of its states - as a participant." []
comment: This classes asserted subclasses will be moved away as it should be an inferred class.
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:02500036
name: environmental pollution
def: "An environmental system process that results in the introduction of contaminants into an environment." [https://en.wikipedia.org/wiki/Pollution]
comment: Pollutants may be material or immaterial (e.g. heat energy)
synonym: "pollution" EXACT []
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:02500037
name: air pollution
def: "A pollution process during which particulates or other contaminants are released into a portion of air." []
is_a: ENVO:02500036 ! environmental pollution
intersection_of: ENVO:02500036 ! environmental pollution
intersection_of: BFO:0000066 ENVO:00002005 ! occurs in air
relationship: BFO:0000066 ENVO:00002005 ! occurs in air

[Term]
id: ENVO:02500038
name: soil pollution
def: "A pollution process during which contaminants are released into soil." [https://en.wikipedia.org/wiki/Soil_pollution]
is_a: ENVO:02500036 ! environmental pollution
intersection_of: ENVO:02500036 ! environmental pollution
intersection_of: BFO:0000066 ENVO:00001998 ! occurs in soil
relationship: BFO:0000066 ENVO:00001998 ! occurs in soil
relationship: RO:0002234 ENVO:00002116 ! has output contaminated soil

[Term]
id: ENVO:02500039
name: water pollution
def: "A pollution process during which contaminants are released into water." []
is_a: ENVO:02500036 ! environmental pollution

[Term]
id: ENVO:02500040
name: plastic pollution
def: "A pollution process during which plastic contaminants are released into an environmental material." [https://en.wikipedia.org/wiki/Plastic_pollution]
is_a: ENVO:02500036 ! environmental pollution

[Term]
id: ENVO:02500042
name: pollution control
def: "A planned process during which the amount of pollutants released into an environmental system is regulated." []
is_a: BFO:0000015 ! process
is_a: ENVO:02500026 ! anthropogenic modulatory intervention process
intersection_of: ENVO:02500026 ! anthropogenic modulatory intervention process
intersection_of: RO:0002211 ENVO:02500036 ! regulates (processual) environmental pollution
relationship: RO:0002211 ENVO:02500036 ! regulates (processual) environmental pollution

[Term]
id: ENVO:02500044
name: urban pollution
def: "A pollution process that results in increased levels of pollutants in an urban environment." []
is_a: ENVO:02500036 ! environmental pollution
intersection_of: ENVO:02500036 ! environmental pollution
intersection_of: BFO:0000066 ENVO:01000249 ! occurs in urban biome
relationship: BFO:0000066 ENVO:01000249 ! occurs in urban biome
relationship: RO:0002233 ENVO:01000249 ! has input urban biome

[Term]
id: ENVO:03000008
name: compaction process
def: "A physical process during which atoms, molecules, or other consituents of a material entity are forced closer together." [https://en.wikipedia.org/wiki/Compaction]
is_a: ENVO:02500000 ! environmental system process
relationship: RO:0002234 ENVO:06105205 ! has output compacted soil

[Term]
id: ENVO:03000009
name: material accumulation process
def: "A process during which the mass of one or more materials, present within a given site, increases." []
comment: Experimental class for structural purposes not recommended for annotation. A material accumulation process ends a material transport process.
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:03000010
name: material transport process
def: "A process during which material is displaced from its original location and transported either to a new location or back to the original location." []
comment: Experimental class for structural purposes not recommended for annotation.
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:03000016
name: material decumulation process
def: "A process during which a mass composed of one or more environmental materials, present within a given site, decreases." [https://www.merriam-webster.com/dictionary/decumulation]
comment: Experimental class for structural purposes not recommended for annotation.
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:03000033
name: marine sediment
def: "Sediment which has been transported through the marine water column, settling on the seafloor." [https://en.wikipedia.org/wiki/Pelagic_sediment#_note-8]
comment: Particles of marine sediment are primarily generated by 1) processes in terrestrial systems and transported to the marine realm by the action of rivers or aeolian processes (amongst other routes) , 2) marine organisms, 3) chemical processes in seawater, or 4) cosmogeneous input.
synonym: "marine sediments" EXACT []
is_a: ENVO:00002007 ! sediment
relationship: RO:0002220 ENVO:00001999 ! adjacent to marine water body
relationship: RO:0002353 ENVO:03000036 ! output of sedimentation in a water body

[Term]
id: ENVO:03000036
name: sedimentation in a water body
def: "A material accumulation process during which solid particles are pulled through a water body by gravitation or centrifugal force and which ends when they settle on a solid surface." []
is_a: ENVO:03000009 ! material accumulation process
relationship: BFO:0000051 ENVO:01000875 ! has part precipitation process
relationship: BFO:0000066 ENVO:00000063 ! occurs in water body
relationship: RO:0000057 ENVO:01000060 ! has participant particulate environmental material
relationship: RO:0002229 ENVO:03000010 ! ends material transport process

[Term]
id: ENVO:03000043
name: material transformation process
def: "A process during which a portion of some environmental material is converted into a different material or a collection of materials." []
comment: Experimental class for structural purposes not recommended for annotation. A material transformation process only refers to ENVO:environmental material classes (e.g. bulk and typically impure substances), rather than transformations converting a specific chemical into another.
is_a: ENVO:02500000 ! environmental system process
relationship: RO:0002233 ENVO:00010483 ! has input environmental material
relationship: RO:0002234 ENVO:00010483 ! has output environmental material

[Term]
id: ENVO:03000055
name: desublimation of water vapour into ice
def: "A desublimation process during which water vapour is frozen into water ice." []
is_a: ENVO:01000726 ! desublimation process
is_a: ENVO:02500031 ! hydrological process
relationship: RO:0002233 ENVO:00002006 ! has input liquid water

[Term]
id: ENVO:03000088
name: methane-laden permafrost
def: "Permafrost which contains pockets of trapped methane gas." [http://www.nature.com/news/mysterious-siberian-crater-attributed-to-methane-1.15649, http://www.sciencealert.com/7-000-huge-gas-bubbles-have-formed-under-siberia-and-could-explode-at-any-moment]
comment: Other hydrocarbon gasses such as carbon dioxide may also be present. These pockets can be sufficently large that the permafrost surface will undulate when pressure is applied.
synonym: "bulgunyakh" EXACT []
is_a: ENVO:00000134 ! permafrost
intersection_of: ENVO:00000134 ! permafrost
intersection_of: BFO:0000051 CHEBI:16183 ! has part methane
relationship: BFO:0000051 CHEBI:16183 ! has part methane

[Term]
id: ENVO:03000092
name: gas emission process
def: "A material transport process during which a portion of gaseous environmental material is transported into the atmosphere." [https://en.wikipedia.org/wiki/Greenhouse_gas]
is_a: ENVO:03000010 ! material transport process

[Term]
id: ENVO:03000093
name: hydrocarbon gas emission process
def: "A gas emission process during which a portion of hydrocarbon gas is transported into the atmosphere." [https://www.epa.gov/ghgemissions/overview-greenhouse-gases]
comment: Some hydrocarbon gasses within the atmosphere contribute to the planetary green house gas effect by increasing absorption of solar energy.
is_a: ENVO:03000092 ! gas emission process
relationship: RO:0000057 ENVO:01000554 ! has participant hydrocarbon gas
relationship: RO:0002411 ENVO:02500004 ! causally upstream of greenhouse effect

[Term]
id: ENVO:03000094
name: methane gas emission process
def: "A hydrocarbon gas emission process during which a portion of methane gas is transported into the atmosphere." [https://www.epa.gov/ghgemissions/overview-greenhouse-gases]
comment: Methane is emitted during the production and transport of coal, natural gas, and oil. Methane emissions also result from livestock and other agricultural practices and by the decay of organic waste in municipal solid waste landfills.
is_a: ENVO:03000093 ! hydrocarbon gas emission process
relationship: RO:0000057 CHEBI:16183 ! has participant methane

[Term]
id: ENVO:03000110
name: cryoform
def: "A solid astronomical body part which is primarily composed of a continuous mass of snow and/or ice." []
is_a: ENVO:00000191 ! solid astronomical body part

[Term]
id: ENVO:03000111
name: snow mass
def: "A mass of snow." []
xref: http://sweetontology.net/phenCryo/Accumulation
is_a: ENVO:01001691 ! mass of compounded environmental materials
intersection_of: ENVO:01001691 ! mass of compounded environmental materials
intersection_of: RO:0002473 ENVO:01000406 ! composed primarily of snow
relationship: RO:0002354 ENVO:01001617 ! formed as result of snow accumulation process
relationship: RO:0002473 ENVO:01000406 ! composed primarily of snow

[Term]
id: ENVO:03000123
name: concentration of nitrate and nitrite in liquid water
def: "The concentration of nitrate and nitrite when measured in liquid water." []
synonym: "liquid water nitrate and nitrite concentration" EXACT []
is_a: PATO:0000033 ! concentration of
union_of: ENVO:3100022 ! concentration of nitrate in liquid water
union_of: ENVO:3100023 ! concentration of nitrite in liquid water

[Term]
id: ENVO:03000127
name: acid rainfall
def: "A water-based rainfall process during which water droplets with increased acidity fall towards a planetary surface." [https://en.wikipedia.org/wiki/Acid_rain]
comment: On Earth, the acidity of raindrops is typically increased through interactions of water molecules with sulfur dioxide or nitrogen oxide, released into the atmosphere by natural or anthropogenic processes.
is_a: ENVO:01000830 ! water-based rainfall
is_a: ENVO:01000982 ! water flow process
relationship: RO:0000057 ENVO:01000358 ! has participant acidic water

[Term]
id: ENVO:03000128
name: acidic water-based rain
def: "Water-based rain which has increased acidity." [https://en.wikipedia.org/wiki/Acid_rain]
comment: On Earth, the acidity of raindrops is typically increased through interactions of water molecules with sulfur dioxide or nitrogen oxide, released into the atmosphere by natural or anthropogenic processes.
synonym: "acid rain" EXACT []
is_a: ENVO:01001565 ! water-based rain
relationship: RO:0000056 ENVO:03000127 ! participates in acid rainfall
relationship: RO:0000086 PATO:0001429 ! has quality acidic

[Term]
id: ENVO:03000143
name: cryosphere
def: "An astronomical body part which is composed primarily of environmental materials in their frozen form." [https://orcid.org/0000-0003-4808-4736]
comment: The term generally refers to the portions of the Earth where water is in solid form, including snow cover, floating ice, glaciers, ice caps, ice sheets, seasonally frozen ground and perennially frozen ground (permafrost). The Cryosphere may be divided into the cryoatmosphere, the cryohydrosphere (snow cover, glaciers, and river, lake and sea Ice) and the cryolithosphere (perennially and seasonally cryotic ground, rock glacier). Some definitions consider the cryosphere to include any area of Earth which is sufficiently cold for pure water to freeze for at least a part of each year. It should be noted that "Some authorities exclude the earth's atmosphere from the Earth's Cryosphere; others restrict the term Cryosphere to the regions of the earth's crust where Permafrost exists."\n\nDefinitions of Cryosphere come from several glossaries including:\n- PhysicalGeography.net http://physicalgeography.net/\n-  van Everdingen, Robert, ed., 2005 (1998 revised May 2005). Multi-language glossary of permafrost and related ground-ice terms. Boulder, CO: National Snow and Ice Data Center/World Data Center for Glaciology. [https://globalcryospherewatch.org/reference/glossary_docs/Glossary_of_Permafrost_and_Ground-Ice_IPA_2005.pdf]\n- American Meteorological Society, 2015. Glossary of Meteorology [online], Available at: http://glossary.ametsoc.org/wiki/Main_Page. [Accessed 27/01/2017].\n- EU Climate-ADAPT (The European Climate Adaptation Platform), no date, Glossary, Available from: http://climate-adapt.eea.europa.eu/glossary\n- IPCC, 2014: Annex II: Glossary [Agard, J., Schipper, E. L. F., (ed.)]. In: Climate Change 2014: Impacts, Adaptation, and Vulnerability. Contribution of Working Group II to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change [Birkmann, J., Campos, M., Dubeux, C., Nojiri, Y., Olsson, L., Osman-Elasha, B., Pelling, M., Prather, M. J., Rivera-Ferre M. G., Ruppel, O. C., Sallenger, A., Smith, K. R., St. Clair, A. L.,]. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA. [Link]\n- NSIDC, The National Snow and Ice Data Center glossary is available at https://nsidc.org/cryosphere/glossary, Last accessed [26/01/2016].\n- Trombotto, D., P. Wainstein & L. Arenson, 2014, Guía Terminológica de la Geocriología Sudamericana” / “Terminological Guide of the South American Geocryology, 1a ed. 128 pp. [Link]\n- UNESCO-WMO, 2012, International Glossary of Hydrology, 3rd edition, WMO-No. 385. [Link] {xref="https://orcid.org/0000-0003-4808-4736"}
xref: http://sweetontology.net/realm/Cryosphere
is_a: ENVO:01000813 ! astronomical body part

[Term]
id: ENVO:03000147
name: thickness of snow
def: "The thickness of some snow." []
synonym: "snow thickness" EXACT []
xref: http://sweetontology.net/propSpaceThickness/SnowCover {comment="Please also see \"snow cover\" in ENVO which maps to an alternative snow cover in SWEET."}
is_a: PATO:0000915 ! thickness
intersection_of: PATO:0000915 ! thickness
intersection_of: RO:0000052 ENVO:01000406 ! characteristic of snow
relationship: RO:0000052 ENVO:01000406 ! characteristic of snow

[Term]
id: ENVO:03400004
name: heavy snowfall
def: "Snowfall which has an increased rate." [https://w1.weather.gov/glossary/index.php?word=HEAVY+SNOW]
comment: This generally means snowfall accumulating to 4 inches or more in depth in 12 hours or less; or snowfall accumulating to 6 inches or more in depth in 24 hours or less. In forecasts, snowfall amounts are expressed as a range of values, e.g., "8 to 12 inches." However, in heavy snow situations where there is considerable uncertainty concerning the range of values, more appropriate phrases are used, such as "...up to 12 inches..." or alternatively "...8 inches or more...". {xref="https://w1.weather.gov/glossary/index.php?word=HEAVY+SNOW"}
synonym: "intense snowfall" EXACT []
xref: http://sweetontology.net/phenAtmoPrecipitation/HeavySnowfall
is_a: ENVO:01000895 ! snowfall
intersection_of: ENVO:01000895 ! snowfall
intersection_of: RO:0000086 PATO:0000912 ! has quality increased rate
relationship: RO:0000086 PATO:0000912 ! has quality increased rate

[Term]
id: ENVO:03500012
name: ultrasound radiation
def: "An acoustic radiation process during which waves that transmit sound energy at frequencies above 20 kHz are emitted by a source." []
xref: http://purl.bioontology.org/ontology/npo#NPO_1744
is_a: ENVO:01001027 ! acoustic radiation

[Term]
id: ENVO:03500013
name: mid-infrared radiation
def: "An infrared radiation during which waves with frequencies between 30 THz and 120 THz and with wavelengths between 10 micrometers and 2.5 micrometers are emitted by a source." []
xref: http://purl.bioontology.org/ontology/npo#NPO_1739
is_a: ENVO:21001214 ! infrared radiation

[Term]
id: ENVO:03500014
name: near-infrared radiation
def: "An infrared radiation during which waves with frequencies between 120 THz and 400 THz and with wavelengths between 2.5 micrometers and 750 nanometers are emitted by a source." []
xref: http://purl.bioontology.org/ontology/npo#NPO_1740
is_a: ENVO:21001214 ! infrared radiation

[Term]
id: ENVO:03500015
name: far-infrared radiation
def: "An infrared radiation which consists of waves with frequencies between 300 GHz and 30 THz and with wavelengths between 1 mm and 10 micrometers are emitted by a source." []
xref: http://purl.bioontology.org/ontology/npo#NPO_1738
is_a: ENVO:21001214 ! infrared radiation

[Term]
id: ENVO:03501134
name: healthcare facility
def: "A human construction in which healthcare is provided." [https://en.wikipedia.org/wiki/Health_facility]
synonym: "health facility" EXACT []
synonym: "medical facility" EXACT []
is_a: ENVO:00000070 ! human construction

[Term]
id: ENVO:03501300
name: manure
def: "An environmental material consisting of organic matter from plants and/or animals that is used in agriculture as fertilizer." [https://en.wikipedia.org/wiki/Manure]
comment: Most manure consists of animal feces; other sources include compost and green manure.
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:03501333
name: child care environment
def: "An anthropogenic environment which is designed for child care." []
synonym: "childcare environment" EXACT []
is_a: ENVO:01000313 ! anthropogenic environment
relationship: BFO:0000051 ENVO:01000927 ! has part day care building

[Term]
id: ENVO:03510000
name: wood dust
def: "Dust which is 1) generated when wood is processed and 2) composed primarily of cellulose, polyoses, and lignin." []
comment: Wood dust is typically generated through processes where wood is chipped, sawed, turned, drilled or sanded. The chemical composition of wood dust depends on the species of tree. Wood dust is not typically produced for specific uses. However, it is used commercially for wood composts. The primary routes of potential human exposure to wood dust are inhalation and dermal contact. It is known to be a human carcinogen.
xref: http://purl.obolibrary.org/obo/NCIT_C44463
is_a: ENVO:00002008 ! dust

[Term]
id: ENVO:03510001
name: brake fluid
def: "A hydraulic fluid which is 1) used in hydraulic brake and hydraulic clutch applications in vehicles to amplify braking force and 2) composed primarily of ethylene glycol, polyglycols, silicone fluids, and isobutyl alcohol." [https://doi.org/10.1520/JTE14254, https://en.wikipedia.org/wiki/Brake_fluid]
is_a: ENVO:03510004 ! hydraulic fluid

[Term]
id: ENVO:03510002
name: automatic transmission fluid
def: "Fluid used for valve operation, brake band friction, and gear lubrication within an automatic vehicle transmission." [https://en.wikipedia.org/wiki/Automatic_transmission_fluid]
synonym: "ATF" EXACT []
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510003
name: famine
def: "An environmental system process during which populations have reduced access to food, causing increased hunger, malnutrition, and consequent mortality." []
is_a: ENVO:02500000 ! environmental system process

[Term]
id: ENVO:03510004
name: hydraulic fluid
def: "A medium by which power is transferred in hydraulic machinery." [https://en.wikipedia.org/wiki/Hydraulic_fluid]
comment: Common hydraulic fluids are based on mineral oil or water.
xref: http://purl.enanomapper.org/onto/ENM_8000199
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510005
name: motor oil
def: "A lubricant for internal combustion engines which 1) reduces friction and wear 2) cleans the engine 3) neutralizes acids 4) improves sealing of piston rings, and 5) cools the engine." [https://en.wikipedia.org/wiki/Motor_oil]
synonym: "engine lubricant" EXACT []
synonym: "engine oil" EXACT []
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510006
name: diesel fuel
def: "A liquid fuel used in diesel engines, whose fuel ignition takes place, without any spark, as a result of compression of the inlet air mixture and then injection of fuel." [https://en.wikipedia.org/wiki/Diesel_fuel, https://www.eia.gov/energyexplained/diesel-fuel/]
is_a: ENVO:00002984 ! petroleum

[Term]
id: ENVO:03510007
name: gasoline
def: "A clear petroleum-derived flammable liquid which is used as fuel in most spark-ignited internal combustion engines." [https://en.wikipedia.org/wiki/Gasoline]
comment: Gasoline consists mostly of organic compounds obtained by the fractional distillation of petroleum, enhanced with a variety of additives.
synonym: "gas" EXACT []
synonym: "petrol" EXACT []
is_a: ENVO:00002984 ! petroleum

[Term]
id: ENVO:03510008
name: diesel exhaust
def: "A gas which results from the incomplete or complete combustion of diesel fuel." []
xref: http://purl.obolibrary.org/obo/NCIT_C113679
is_a: ENVO:01000797 ! gaseous environmental material
relationship: BFO:0000051 CHEBI:15368 ! has part acrolein
relationship: BFO:0000051 CHEBI:15377 ! has part water
relationship: BFO:0000051 CHEBI:16134 ! has part ammonia
relationship: BFO:0000051 CHEBI:16136 ! has part hydrogen sulfide
relationship: BFO:0000051 CHEBI:16183 ! has part methane
relationship: BFO:0000051 CHEBI:16526 ! has part carbon dioxide
relationship: BFO:0000051 CHEBI:16716 ! has part benzene
relationship: BFO:0000051 CHEBI:16842 ! has part formaldehyde
relationship: BFO:0000051 CHEBI:17245 ! has part carbon monoxide
relationship: BFO:0000051 CHEBI:17578 ! has part toluene
relationship: BFO:0000051 CHEBI:17790 ! has part methanol
relationship: BFO:0000051 CHEBI:18407 ! has part hydrogen cyanide
relationship: BFO:0000051 CHEBI:18422 ! has part sulfur dioxide
relationship: BFO:0000051 CHEBI:24840 ! has part inorganic sulfate salt
relationship: BFO:0000051 CHEBI:24873 ! has part iron molecular entity
relationship: BFO:0000051 CHEBI:25567 ! has part nitrous acid
relationship: BFO:0000051 CHEBI:26836 ! has part sulfuric acid
relationship: BFO:0000051 CHEBI:27364 ! has part zinc molecular entity
relationship: BFO:0000051 CHEBI:30751 ! has part formic acid
relationship: BFO:0000051 CHEBI:33415 ! has part elemental carbon
relationship: BFO:0000051 CHEBI:33585 ! has part lead molecular entity
relationship: BFO:0000051 CHEBI:33666 ! has part polycyclic hydrocarbon
relationship: BFO:0000051 CHEBI:33749 ! has part platinum molecular entity
relationship: BFO:0000051 CHEBI:35196 ! has part nitrogen oxide
relationship: BFO:0000051 CHEBI:37133 ! has part barium molecular entity
relationship: BFO:0000051 CHEBI:39478 ! has part buta-1,3-diene
relationship: BFO:0000051 CHEBI:48107 ! has part nitric acid
relationship: BFO:0000051 CHEBI:51084 ! has part inorganic nitrate salt
relationship: BFO:0000051 CHEBI:5686 ! has part heterocyclic compound
relationship: BFO:0000051 ENVO:01000060 ! has part particulate environmental material
relationship: RO:0001000 ENVO:03510006 ! derives from diesel fuel

[Term]
id: ENVO:03510009
name: gasoline exhaust
def: "A gas which results from the complete or incomplete combustion of gasoline fuel." [https://www.ncbi.nlm.nih.gov/books/NBK531367/]
is_a: ENVO:01000797 ! gaseous environmental material
relationship: BFO:0000051 CHEBI:15368 ! has part acrolein
relationship: BFO:0000051 CHEBI:15377 ! has part water
relationship: BFO:0000051 CHEBI:16134 ! has part ammonia
relationship: BFO:0000051 CHEBI:16136 ! has part hydrogen sulfide
relationship: BFO:0000051 CHEBI:16183 ! has part methane
relationship: BFO:0000051 CHEBI:16526 ! has part carbon dioxide
relationship: BFO:0000051 CHEBI:16716 ! has part benzene
relationship: BFO:0000051 CHEBI:16842 ! has part formaldehyde
relationship: BFO:0000051 CHEBI:17245 ! has part carbon monoxide
relationship: BFO:0000051 CHEBI:17578 ! has part toluene
relationship: BFO:0000051 CHEBI:17790 ! has part methanol
relationship: BFO:0000051 CHEBI:18407 ! has part hydrogen cyanide
relationship: BFO:0000051 CHEBI:18422 ! has part sulfur dioxide
relationship: BFO:0000051 CHEBI:24840 ! has part inorganic sulfate salt
relationship: BFO:0000051 CHEBI:25567 ! has part nitrous acid
relationship: BFO:0000051 CHEBI:30751 ! has part formic acid
relationship: BFO:0000051 CHEBI:33585 ! has part lead molecular entity
relationship: BFO:0000051 CHEBI:33666 ! has part polycyclic hydrocarbon
relationship: BFO:0000051 CHEBI:33749 ! has part platinum molecular entity
relationship: BFO:0000051 CHEBI:35196 ! has part nitrogen oxide
relationship: BFO:0000051 CHEBI:39478 ! has part buta-1,3-diene
relationship: BFO:0000051 CHEBI:48107 ! has part nitric acid
relationship: BFO:0000051 CHEBI:51084 ! has part inorganic nitrate salt
relationship: BFO:0000051 CHEBI:5686 ! has part heterocyclic compound
relationship: BFO:0000051 ENVO:01000060 ! has part particulate environmental material
relationship: RO:0001000 ENVO:03510007 ! derives from gasoline

[Term]
id: ENVO:03510010
name: dye
def: "A coloured substance that chemically bonds to the substrate to which it is being applied" [https://en.wikipedia.org/wiki/Dye]
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510011
name: leather dye
def: "Pigments carried by solvents or water which are applied to leather to be absorbed into the pores of the leather to deposit coloration." [https://en.wikipedia.org/wiki/Leather_crafting]
is_a: ENVO:03510010 ! dye

[Term]
id: ENVO:03510012
name: paper dye
def: "Dyes used for the coloration or brightening of paper." [https://en.wikipedia.org/wiki/Dye]
is_a: ENVO:03510010 ! dye

[Term]
id: ENVO:03510013
name: textile dye
def: "Dyes utilized for coloring textiles such as wool or cellulose fibers." [https://www.britannica.com/topic/textile/Dyeing-and-printing]
comment: Textile dyes may include acid dyes, substantive dyes, mordant dues, sulfur dyes, azoic dyes, and disperse dyes.
synonym: "fabric dye" EXACT []
is_a: ENVO:03510010 ! dye

[Term]
id: ENVO:03510014
name: India ink
def: "A black or colored ink which is 1) used for writing, printing, and drawing and 2) made from fine soot (lampblack) and water." [https://en.wikipedia.org/wiki/India_ink]
synonym: "Chinese ink" EXACT []
synonym: "Indian ink" EXACT []
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510015
name: xanthan gum
def: "A polysaccharide that functions as an emulsifier, stabilizer, and thickener in mixtures." []
xref: http://purl.obolibrary.org/obo/DRON_00723355
xref: http://purl.obolibrary.org/obo/FOODON_03413321
xref: http://purl.obolibrary.org/obo/NCIT_C84244
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:03510016
name: tragacanth
def: "A naturally occurring plant-based gum, which functions as a viscous, odorless, tasteless, water-soluble mixture of polysaccharides that absorbs water to become a gel/paste." []
comment: Tragacanth has many uses, including as an emulsifier, thickener, stabilizer, and texturant additive for foods, pharmaceuticals, and art materials.
synonym: "shiraz gum" EXACT []
synonym: "tragacanth gum" EXACT []
xref: http://purl.obolibrary.org/obo/DRON_00723978
xref: http://purl.obolibrary.org/obo/FOODON_03413310
xref: http://purl.obolibrary.org/obo/NCIT_C84223
xref: http://purl.obolibrary.org/obo/OMIT_0014984
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:03510017
name: fountain pen ink
def: "Water based ink intended for use with fountain ink pens." [https://en.wikipedia.org/wiki/Fountain_pen_ink]
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510018
name: resin
def: "A solid or highly viscous plant or synthetic based substance that is typically convertible into polymers." [https://en.wikipedia.org/wiki/Resin]
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:03510019
name: cleaning agent
def: "A liquid, powder, spray, or granule used to remove dirt, including dust, stains, bad smells, and clutter on surfaces." [https://en.wikipedia.org/wiki/Cleaning_agent]
synonym: "cleaning product" EXACT []
is_a: ENVO:2000000 ! chemical product

[Term]
id: ENVO:03510020
name: degreaser
def: "A cleaning agent which 1) contains organic solvents and 2) dissolves oils and fats for the removal of grease." [https://en.wikipedia.org/wiki/Cleaning_agent#Degreasers]
synonym: "solvent degreaser" EXACT []
is_a: ENVO:03510019 ! cleaning agent

[Term]
id: ENVO:03510021
name: varnish
def: "A clear transparent hard protective film or finish, primarily used for wood finishing applications." [https://en.wikipedia.org/wiki/Varnish]
comment: Varnish is traditionally composed of a drying oil, a resin, and a thinner or solvent.
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510022
name: resin (gum) varnish
def: "A varnish containing a natural, plant- or insect-derived substance dissolved in a solvent, called spirit varnish or solvent varnish." [https://en.wikipedia.org/wiki/Varnish]
synonym: "gum varnish" EXACT []
synonym: "resin varnish" EXACT []
is_a: ENVO:03510021 ! varnish

[Term]
id: ENVO:03510023
name: shellac
def: "A resin secreted by the female lac bug, which is dissolved in alcohol to be used as a brush-on colorant, food glaze, and wood finish." [https://en.wikipedia.org/wiki/Shellac]
synonym: "shellack" EXACT []
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:03510024
name: lacquer
def: "A category of hard and potentially shiny (clear or colored) finishes which can be applied to materials including wood or metal." [https://en.wikipedia.org/wiki/Lacquer]
is_a: ENVO:2000000 ! chemical product

[Term]
id: ENVO:03510025
name: paint thinner
def: "A solvent that can dissolve paint and reduce viscosity of paint or \"thin\" it." [https://www.truevaluepaint.com/paint/exterior/prep_cleanup_and_safety/use_paint_thinner_properly.aspx#\:~\:text=Paint%20thinners%20are%20solvents%20that\,cleanup%20of%20spills%20or%20splatters]
comment: Paint thinners can aid in removal of paint from brushes, rollers, or in spill cleanup.
is_a: ENVO:2000000 ! chemical product

[Term]
id: ENVO:03510026
name: acrylic paint medium
def: "A liquid, gel, or paste that can be mixed into acrylic paint to alter paint consistency and properties." [https://en.wikipedia.org/wiki/Acrylic_paint]
is_a: ENVO:03510025 ! paint thinner

[Term]
id: ENVO:03510027
name: enamel thinner
def: "A paint thinner specific for altering the viscosity of enamel paints." []
is_a: ENVO:03510025 ! paint thinner

[Term]
id: ENVO:03510028
name: oil paint thinner
def: "A solvent used to thin oil-based paints or clean up after their use." [https://en.wikipedia.org/wiki/Paint_thinner]
is_a: ENVO:03510025 ! paint thinner

[Term]
id: ENVO:03510029
name: primer (paint)
def: "A paint product which adheres to surfaces and forms a binding layer, preparing it to receive paint." [https://en.wikipedia.org/wiki/Primer_(paint)]
is_a: ENVO:02000123 ! paint

[Term]
id: ENVO:03510030
name: vitreous enamel
def: "A smooth, durable vitreous coating which is made by fusing powdered glass to a substrate." [https://en.wikipedia.org/wiki/Vitreous_enamel]
comment: Enamel can be used on metal, glass, ceramics, stone, or any material able to withstand the fusing temperature. Enamel is made by 1) firing, melting the powder and 2) allowing allowing it to flow across a surface to then harden.
synonym: "porcelain enamel" EXACT []
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510031
name: oil-based paint
def: "A slow-drying paint that consists of particles of pigment suspended in a drying oil, commonly linseed oil." [https://en.wikipedia.org/wiki/Oil_paint]
synonym: "oil paint" EXACT []
is_a: ENVO:02000123 ! paint

[Term]
id: ENVO:03510032
name: acrylic paint
def: "A water soluble, fast-drying paint made of pigment suspended in acrylic polymer emulsion." [https://en.wikipedia.org/wiki/Acrylic_paint]
is_a: ENVO:02000123 ! paint

[Term]
id: ENVO:03510033
name: luminescent paint
def: "A paint that exhibits luminescence, giving off visible light through fluorescence, phosphorescence, or radioluminescence." [https://en.wikipedia.org/wiki/Luminous_paint]
synonym: "luminous paint" EXACT []
is_a: ENVO:02000123 ! paint

[Term]
id: ENVO:03510034
name: turpentine
def: "A fluid obtained by the distillation of resin harvested from living trees, primarily used as a solvent." [https://en.wikipedia.org/wiki/Turpentine]
comment: Turpentine is composed of terpenes.
synonym: "oil of turpentine" EXACT []
synonym: "spirit of turpentine" EXACT []
synonym: "turps" EXACT []
synonym: "wood turpentine" EXACT []
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510035
name: naphtha
def: "A flammable liquid hydrocarbon mixture produced from natural gas condensates, petroleum distillates, and the distillation of coal tar and peat." [https://en.wikipedia.org/wiki/Naphtha]
comment: Light and heavy varieties may consist of distinct quantities of carbon atoms per molecule.
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03510036
name: rock dust
def: "Dust which is composed of minerals and trace elements, generated by  finely crushed rock." [https://en.wikipedia.org/wiki/Rockdust]
comment: Rock dust is widely used in mining to prevent coal dust explosions, or in agriculture for organic farming uses.
synonym: "rock powder" EXACT []
is_a: ENVO:00002008 ! dust

[Term]
id: ENVO:03510037
name: radioactive material
def: "Any material containing unstable atoms that emit ionizing radiation as it decays." [https://www.ehs.iastate.edu/research/radiation/radioactive-materials]
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:03510038
name: volume of cyanoacrylate
def: "An environmental material which is primarily composed of cyanoacrolate." [https://en.wikipedia.org/wiki/Cyanoacrylate]
comment: Cyanoacrylates have industrial, medical, and household uses. A strong fast-acting adhesive which is an ester of cyanoacrylic acid.
is_a: ENVO:00010483 ! environmental material
relationship: RO:0000085 ENVO:00003076 ! has function glue

[Term]
id: ENVO:03510040
name: stain
def: "A preparation with dye or pigment used to deposit coloration to a substrate." [https://www.merriam-webster.com/dictionary/stain]
is_a: ENVO:2000000 ! chemical product

[Term]
id: ENVO:03510041
name: wood stain
def: "A stain which has colorants dissolved and/or suspended in a vehicle or solvent, used to add color to wood." [https://en.wikipedia.org/wiki/Wood_stain]
comment: Wood stain is designed to add color to substrates, while still leaving some of the substrate visible.
is_a: ENVO:03510040 ! stain

[Term]
id: ENVO:03510055
name: rubber cement
def: "An environmental material which is composed of elastic polymers mixed in a solvent." []
comment: Solvents typically used include acetone, hexane, heptane or toluene.
synonym: "cow gum" EXACT []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:2000045 ! hydrocarbon-based environmental material
relationship: BFO:0000051 CHEBI:28798 ! has part rubber particle
relationship: BFO:0000051 CHEBI:30879 ! has part alcohol
relationship: RO:0000085 ENVO:00003076 ! has function glue
relationship: RO:0002473 CHEBI:43098 ! composed primarily of heptane

[Term]
id: ENVO:03510056
name: methyl cellulose paste
def: "An environmental material which is 1) composed primarily of methyl cellulose and water, and 2) formulated to fix wallpaper to walls." []
synonym: "wallpaper adhesive" EXACT []
synonym: "wallpaper paste" EXACT []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:01000155 ! organic material
relationship: RO:0000085 ENVO:00003076 ! has function glue
relationship: RO:0002473 CHEBI:15377 ! composed primarily of water
relationship: RO:0002473 CHEBI:53448 ! composed primarily of methyl cellulose

[Term]
id: ENVO:03510057
name: permanent hair dye
def: "An environmental material which is 1) manufactured and 2) primarily composed of hydrogen peroxide and ammonia, and 3) when applied to hair, can alter the natural hair pigments for 6-8 weeks." []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
relationship: RO:0000085 ENVO:03510066 ! has function chemical colorant
relationship: RO:0002473 CHEBI:16134 ! composed primarily of ammonia
relationship: RO:0002473 CHEBI:16240 ! composed primarily of hydrogen peroxide

[Term]
id: ENVO:03510058
name: pharmaceutical ink
def: "A colorant fluid which is 1) manufactured and 2) composed of alcohol, titanium dioxide, and propylene glycol." []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:03510065 ! colorant fluid
relationship: BFO:0000051 CHEBI:16997 ! has part propane-1,2-diol
relationship: BFO:0000051 CHEBI:30879 ! has part alcohol
relationship: BFO:0000051 CHEBI:32234 ! has part titanium dioxide

[Term]
id: ENVO:03510060
name: gel ink
def: "A colorant fluid which is 1) manufactured and 2) composed of copper phthalocyanine, iron oxides, water, and biopolymers." []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:03510065 ! colorant fluid
relationship: BFO:0000051 CHEBI:15377 ! has part water
relationship: BFO:0000051 CHEBI:155903 ! has part copper(II) phthalocyanine
relationship: BFO:0000051 CHEBI:18154 ! has part polysaccharide
relationship: BFO:0000051 CHEBI:50816 ! has part iron oxide

[Term]
id: ENVO:03510061
name: soy ink
def: "A colorant fluid which is 1) manufactured and 2) primarily composed of soybean oil, as well as pigment, resin, and wax." []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:03510065 ! colorant fluid
relationship: BFO:0000051 ENVO:01000575 ! has part wax
relationship: BFO:0000051 ENVO:03510018 ! has part resin
relationship: RO:0000087 CHEBI:26130 ! has role biological pigment
relationship: RO:0002473 CHEBI:166975 ! composed primarily of soybean oil

[Term]
id: ENVO:03510062
name: aqueous inkjet printer ink
def: "A colorant fluid which is 1) manufactured, 2) primarily composed of water, as well as glycol, and dye, and 3) intended for use in inkjet printers." []
is_a: ENVO:00003074 ! manufactured product
is_a: ENVO:0010001 ! anthropogenic environmental material
is_a: ENVO:03510065 ! colorant fluid
relationship: BFO:0000051 CHEBI:13643 ! has part glycol
relationship: BFO:0000051 ENVO:03510010 ! has part dye
relationship: RO:0002473 CHEBI:15377 ! composed primarily of water

[Term]
id: ENVO:03510064
name: emissions from petroleum combustion
def: "An environmental material which is composed primarily of gases and particles produced by the combustion of petroleum fuels." []
is_a: ENVO:00010483 ! environmental material
relationship: RO:0001000 ENVO:00002984 ! derives from petroleum
relationship: RO:0002353 ENVO:01000839 ! output of combustion process

[Term]
id: ENVO:03510065
name: colorant fluid
def: "A liquid environmental material which 1) contains at least one substance which can act as a chemical colorant." []
is_a: ENVO:01000815 ! liquid environmental material
intersection_of: ENVO:01000815 ! liquid environmental material
intersection_of: RO:0000085 ENVO:03510066 ! has function chemical colorant
relationship: RO:0000085 ENVO:03510066 ! has function chemical colorant

[Term]
id: ENVO:03510066
name: chemical colorant
def: "A function which is realised by a chemical when applied to a material, such that it alters the material's colour." []
is_a: BFO:0000034 ! function
relationship: RO:0000052 CHEBI:24431 ! characteristic of chemical entity

[Term]
id: ENVO:03520000
name: low atmospheric level
comment: A part of the troposphere which extends from the Earth's surface to 2 km (0 - 6500 ft) height. {xref="levels"}
synonym: "low étage" EXACT []
is_a: ENVO:01000543 ! atmospheric layer
relationship: BFO:0000051 ENVO:01000323 ! has part atmospheric boundary layer

[Term]
id: ENVO:03520001
name: middle atmospheric level
comment: A part of the troposphere which extends from 2 km to 4 km (6 500 – 13 000 ft) height in the polar region, from 2 km to 7 km (6 500 – 23 000 ft) height in the temperate region, and from 2 km to 8 km (6 500 – 25 000 ft) height in the tropical region. {xref="levels"}
synonym: "middle étage" EXACT []
is_a: ENVO:01000543 ! atmospheric layer

[Term]
id: ENVO:03520002
name: high atmospheric level
comment: A part of the troposphere which extends from 3 km to 8 km (10 000 – 25 000 ft) height in the polar region, from 5 km to 13 km (16 500 – 45 000 ft) height in the temperate region, and from 6 km to 18 km (20 000 – 60 000 ft) height in the tropical region. {xref="levels"}
synonym: "high étage" EXACT []
is_a: ENVO:01000543 ! atmospheric layer

[Term]
id: ENVO:03520003
name: cloud part
def: "A part of a cloud." []
is_a: ENVO:01001784 ! compound astronomical body part
relationship: BFO:0000050 ENVO:01000760 ! part of cloud

[Term]
id: ENVO:03520004
name: cloud base
def: "A cloud part which is closest to the surface of the astronomical body local to the cloud." []
is_a: ENVO:03520003 ! cloud part

[Term]
id: ENVO:03520005
name: cloud top
def: "A cloud part which is furthest from the surface of the astronomical body local to the cloud." []
is_a: ENVO:03520003 ! cloud part

[Term]
id: ENVO:03520007
name: snow crystal
def: "A water ice crystal which is constituted by water molecules aligned in a hexagonal array." [http://www.snowcrystals.com/science/science.html, https://www.athropolis.com/arctic-facts/fact-snow-crystal.htm, https://www.noaa.gov/stories/how-do-snowflakes-form-science-behind-snow]
is_a: ENVO:01000846 ! water ice crystal

[Term]
id: ENVO:03600001
name: chemically contaminated sediment
def: "Sediment which contains some chemical contaminant." [https://en.wikipedia.org/wiki/Contamination]
is_a: ENVO:00002114 ! chemically enriched sediment

[Term]
id: ENVO:03600035
name: cold room
def: "A room which is maintained at lower than ambient temperatures." [https://blog.froztec.com/en/what-is-a-cold-room-and-why-do-you-need-it-for-your-products, https://www.appropedia.org/Cold_room]
comment: Cold rooms are generally used as walk-in storage facilities or to perform tasks requiring cooler ambient temperatures.
synonym: "chiller room" EXACT []
synonym: "cool room" EXACT []
synonym: "refrigerating chamber" EXACT []
is_a: ENVO:01000426 ! room

[Term]
id: ENVO:03600046
name: processed tobacco
def: "A manufactured product which is produced by curing, subsequent aging, slow oxidation and degradation of carotenoids in tobacco leaves." [https://en.wikipedia.org/wiki/Curing_of_tobacco#Processes]
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:03600049
name: smokeless tobacco
def: "Processed tobacco which has been treated for use by placing it between the gum and cheek or lip, chewed, or sniffed, but not smoked." [https://en.wikipedia.org/wiki/Smokeless_tobacco]
is_a: ENVO:03600046 ! processed tobacco

[Term]
id: ENVO:03600050
name: space station
def: "A spacecraft which is capable of supporting a human crew in orbit for an extended period of time." [https://en.wikipedia.org/wiki/Space_station]
synonym: "orbital space station" EXACT []
synonym: "orbital station" EXACT []
is_a: ENVO:01003000 ! spacecraft

[Term]
id: ENVO:03600074
name: aquaculture farm
def: "An agricultural aquatic ecosystem in which fish, crustaceans, mollusks, aquatic plants and algae are cultivated." [https://en.wikipedia.org/wiki/Aquaculture, https://www.dictionary.com/browse/farm]
is_a: ENVO:00000077 ! agricultural ecosystem

[Term]
id: ENVO:03600081
name: cloud water
def: "Fresh water which is harvested from cloud." [https://www.environmentalleader.com/2013/02/steps-to-harvesting-water-from-the-clouds/, https://www.nature.com/articles/s41598-019-41032-4#Abs1]
is_a: ENVO:00002011 ! fresh water

[Term]
id: ENVO:03605006
name: stream water
def: "Water which is part of a stream." []
is_a: ENVO:00002006 ! liquid water
is_a: ENVO:01000813 ! astronomical body part
intersection_of: ENVO:00002006 ! liquid water
intersection_of: BFO:0000050 ENVO:00000023 ! part of stream
relationship: BFO:0000050 ENVO:00000023 ! part of stream

[Term]
id: ENVO:03605007
name: freshwater stream
def: "A stream which is composed primarily of fresh water." []
is_a: ENVO:00000023 ! stream
intersection_of: ENVO:00000023 ! stream
intersection_of: BFO:0000051 ENVO:00002011 ! has part fresh water
relationship: BFO:0000051 ENVO:00002011 ! has part fresh water

[Term]
id: ENVO:03605008
name: freshwater stream biome
def: "A freshwater stream ecosystem which is undergoing climactic ecological succession." []
is_a: ENVO:00000873 ! freshwater biome
is_a: ENVO:03605009 ! freshwater stream ecosystem
intersection_of: ENVO:03605009 ! freshwater stream ecosystem
intersection_of: RO:0000056 ENVO:01001827 ! participates in climactic ecological succession

[Term]
id: ENVO:03605009
name: freshwater stream ecosystem
def: "An ecosystem in which the composition, structure, and function of resident ecological assemblages are primarily determined by a freshwater stream." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:01001789 ! freshwater ecosystem
intersection_of: ENVO:01001789 ! freshwater ecosystem
intersection_of: RO:0002507 ENVO:03605007 ! determined by freshwater stream
relationship: RO:0002507 ENVO:03605007 ! determined by freshwater stream

[Term]
id: ENVO:04000002
name: temperature of sea surface
def: "A water temperature which inheres in water close to the surface of an ocean or sea." [http://www.goosocean.org/components/com_oe/oe.php?task=download&id=34498&version=1.0&lang=1&format=1, https://en.wikipedia.org/wiki/Sea_surface_temperature]
comment: The exact meaning of surface varies according to the measurement method used, but it is between 1 millimetre (0.04 in) and 20 metres (70 ft) below the sea surface.
synonym: "ocean surface temperature" EXACT []
synonym: "sea surface temperature" EXACT []
synonym: "temperature of the ocean surface" EXACT []
is_a: ENVO:09200014 ! temperature of water
relationship: RO:0000052 ENVO:01001581 ! characteristic of sea surface layer

[Term]
id: ENVO:04000003
name: concentration of carbon dioxide in soil
def: "The concentration of carbon dioxide when measured in soil." []
is_a: ENVO:3200071 ! concentration of organic molecular entity in soil

[Term]
id: ENVO:04000004
name: concentration of carbon dioxide in air
def: "The concentration of carbon dioxide when measured in air." []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:04000005
name: concentration of carbon dioxide in freshwater
def: "The concentration of carbon dioxide when measured in freshwater." []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:04000006
name: concentration of carbon dioxide in seawater
def: "The concentration of carbon dioxide when measured in seawater." []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:04000008
name: soil organic matter
def: "Organic material in soil, which consists of plant and animal residues at various stages of decomposition, cells and tissues of soil organisms, and substances synthesized by soil organisms." [https://en.wikipedia.org/wiki/Soil_organic_matter]
is_a: ENVO:01000155 ! organic material
is_a: ENVO:01000813 ! astronomical body part
relationship: BFO:0000050 ENVO:00001998 ! part of soil

[Term]
id: ENVO:04000010
name: soil surface layer
def: "A surface layer which is composed primarily of soil." []
is_a: ENVO:00000191 ! solid astronomical body part
is_a: ENVO:01001311 ! solid surface layer
is_a: ENVO:01001483 ! surface of an astronomical body
is_a: ENVO:06105266 ! soil layer
intersection_of: ENVO:01001311 ! solid surface layer
intersection_of: RO:0002473 ENVO:00001998 ! composed primarily of soil
relationship: BFO:0000050 ENVO:01000820 ! part of pedosphere

[Term]
id: ENVO:04000015
name: carbon sequestration process
def: "A material accumulation process during which atmospheric carbon dioxide is captured and stored." [https://www.usgs.gov/faqs/what-carbon-sequestration?qt-news_science_products=0#qt-news_science_products]
is_a: ENVO:03000009 ! material accumulation process
intersection_of: ENVO:03000009 ! material accumulation process
intersection_of: RO:0000057 ENVO:01000451 ! has participant atmospheric carbon dioxide
relationship: RO:0000057 ENVO:01000451 ! has participant atmospheric carbon dioxide

[Term]
id: ENVO:06105101
name: plastic
def: "An environnmental material which 1) is composed primarily of polymers with high molecular mass and 2) once deformed does not spontaneously return to its original shape." [https://readanddigest.com/what-is-plastic/, https://www.britannica.com/science/plastic#ref82461, https://www.lexico.com/definition/plastic]
comment: "High molecular mass" can be ambiguous as it does not set a threshold for what is considered "high". Here we make no commitment to a threshold.
synonym: "plastica" EXACT []
synonym: "Plastik" EXACT []
synonym: "塑膠" EXACT []
is_a: ENVO:00010483 ! environmental material

[Term]
id: ENVO:06105112
name: synthetic plastic
def: "A plastic which is composed primarily of polymers produced by a manufacturing process." []
synonym: "manufactured plastic" EXACT []
xref: c:5998
xref: http://eurovoc.europa.eu/1837
is_a: ENVO:06105101 ! plastic

[Term]
id: ENVO:06105205
name: compacted soil
def: "A soil which has a high bulk density and/or a low porosity. A compacted soil has a reduced rate of both water infiltration and drainage" [] {comment="https://extension.umn.edu/soil-management-and-health/soil-compaction"}
is_a: ENVO:00001998 ! soil
intersection_of: ENVO:00001998 ! soil
intersection_of: RO:0000086 PATO:0001485 ! has quality condensed
relationship: RO:0000086 PATO:0001485 ! has quality condensed

[Term]
id: ENVO:06105266
name: soil layer
def: "A layer that is composed primarily of soil." []
is_a: ENVO:01000281 ! layer
intersection_of: ENVO:01000281 ! layer
intersection_of: RO:0002473 ENVO:00001998 ! composed primarily of soil
relationship: RO:0002473 ENVO:00001998 ! composed primarily of soil

[Term]
id: ENVO:06105268
name: treated wastewater
def: "Waste water which was converted into an effluent that can be either returned to the water cycle with minimal environmental issues or reused." [https://www.usgs.gov/special-topics/water-science-school/science/wastewater-treatment-water-use]
is_a: ENVO:00002006 ! liquid water
intersection_of: ENVO:00002006 ! liquid water
intersection_of: RO:0002353 ENVO:06105300 ! output of wastewater treatment process
relationship: RO:0002353 ENVO:06105300 ! output of wastewater treatment process

[Term]
id: ENVO:06105271
name: soil texture
def: "Texture which inheres in soil." []
is_a: PATO:0000150 ! texture
intersection_of: PATO:0000150 ! texture
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:06105300
name: wastewater treatment process
def: "A recycling process during which wastewater is treated" []
is_a: ENVO:01000741 ! recycling process

[Term]
id: ENVO:06105304
name: water-holding capacity of soil
def: "Water-holding capacity which inheres in some soil." [https://www.canr.msu.edu/news/why_is_soil_water_holding_capacity_important]
synonym: "soil water-holding capacity" EXACT []
is_a: ENVO:01003001 ! water-holding capacity
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:08000002
name: mouth environment
def: "An environment that is determined by a mouth." [GOC:TermGenie]
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:2100000 ! anatomical entity environment
intersection_of: ENVO:2100000 ! anatomical entity environment
intersection_of: RO:0002507 UBERON:0000165 ! determined by mouth
relationship: RO:0002507 UBERON:0000165 ! determined by mouth

[Term]
id: ENVO:09000004
name: amount of carbon atom in environmental material
def: "The amount of a carbon atom when measured in environmental material." []
synonym: "environmental material carbon atom amount" EXACT []
is_a: PATO:0000070 ! amount

[Term]
id: ENVO:09000005
name: amount of carbon atom in soil
def: "The amount of a carbon atom when measured in soil." []
synonym: "soil carbon atom amount" EXACT []
is_a: ENVO:09000004 ! amount of carbon atom in environmental material

[Term]
id: ENVO:09000006
name: amount of carbon atom in water
def: "The amount of a carbon atom when measured in water." []
synonym: "water carbon atom amount" EXACT []
is_a: ENVO:09000004 ! amount of carbon atom in environmental material

[Term]
id: ENVO:09000007
name: concentration of carbon atom in environmental material
def: "The concentration of a carbon atom when measured in environmental material." []
synonym: "environmental material carbon atom concentration" EXACT []
is_a: ENVO:09000004 ! amount of carbon atom in environmental material
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000008
name: concentration of carbon atom in soil
def: "The concentration of a carbon atom when measured in soil." []
synonym: "soil carbon atom concentration" EXACT []
is_a: ENVO:09000005 ! amount of carbon atom in soil
is_a: ENVO:09000007 ! concentration of carbon atom in environmental material
is_a: ENVO:3200071 ! concentration of organic molecular entity in soil

[Term]
id: ENVO:09000009
name: concentration of carbon atom in water
def: "The concentration of a carbon atom when measured in water." []
synonym: "water carbon atom concentration" EXACT []
is_a: ENVO:09000006 ! amount of carbon atom in water
is_a: ENVO:09000007 ! concentration of carbon atom in environmental material

[Term]
id: ENVO:09000013
name: amount of nitrogen atom in environmental material
def: "The amount of a nitrogen atom when measured in environmental material." []
synonym: "environmental material nitrogen atom amount" EXACT []
is_a: PATO:0000070 ! amount

[Term]
id: ENVO:09000014
name: amount of nitrogen atom in soil
def: "The amount of a nitrogen atom when measured in soil." []
synonym: "soil nitrogen atom amount" EXACT []
is_a: ENVO:09000013 ! amount of nitrogen atom in environmental material

[Term]
id: ENVO:09000015
name: amount of nitrogen atom in water
def: "The amount of a nitrogen atom when measured in water." []
synonym: "water nitrogen atom amount" EXACT []
is_a: ENVO:09000013 ! amount of nitrogen atom in environmental material

[Term]
id: ENVO:09000016
name: concentration of nitrogen atom in environmental material
def: "The concentration of a nitrogen atom when measured in environmental material." []
synonym: "environmental material nitrogen atom concentration" EXACT []
is_a: ENVO:09000013 ! amount of nitrogen atom in environmental material
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000017
name: concentration of nitrogen atom in soil
def: "The concentration of a nitrogen atom when measured in soil." []
synonym: "soil nitrogen atom concentration" EXACT []
is_a: ENVO:09000014 ! amount of nitrogen atom in soil
is_a: ENVO:09000016 ! concentration of nitrogen atom in environmental material

[Term]
id: ENVO:09000018
name: concentration of nitrogen atom in water
def: "The concentration of a nitrogen atom when measured in water." []
synonym: "water nitrogen atom concentration" EXACT []
is_a: ENVO:09000015 ! amount of nitrogen atom in water
is_a: ENVO:09000016 ! concentration of nitrogen atom in environmental material

[Term]
id: ENVO:09000019
name: concentration of chloride in water
def: "The concentration of a chloride when measured in water." []
synonym: "water chloride concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000022
name: concentration of clay in soil
def: "The concentration of a clay when measured in soil." []
synonym: "soil clay concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000023
name: concentration of slit in soil
def: "The concentration of a slit when measured in soil." []
synonym: "soil slit concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000024
name: concentration of sand in soil
def: "The concentration of a sand when measured in soil." []
synonym: "soil sand concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000025
name: concentration of gravel in soil
def: "The concentration of a gravel when measured in soil." []
synonym: "soil gravel concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000026
name: concentration of liquid water in soil
def: "The concentration of a liquid water when measured in soil." []
synonym: "soil liquid water concentration" EXACT []
synonym: "soil moisture content" EXACT []
synonym: "soil water content" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000027
name: concentration of salt in soil
def: "The concentration of a salt when measured in soil." []
synonym: "soil salt concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09000030
name: concentration of soil organic matter in soil
def: "The concentration of a soil organic matter when measured in soil." []
synonym: "soil soil organic matter concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09200000
name: temperature of environmental material
def: "The temperature of some environmental material." []
synonym: "environmental material temperature" EXACT []
is_a: PATO:0000146 ! temperature
intersection_of: PATO:0000146 ! temperature
intersection_of: RO:0000052 ENVO:00010483 ! characteristic of environmental material
relationship: RO:0000052 ENVO:00010483 ! characteristic of environmental material

[Term]
id: ENVO:09200001
name: temperature of air
def: "The temperature of some air." []
synonym: "air temperature" EXACT []
is_a: ENVO:09200000 ! temperature of environmental material
intersection_of: PATO:0000146 ! temperature
intersection_of: RO:0000052 ENVO:00002005 ! characteristic of air
relationship: RO:0000052 ENVO:00002005 ! characteristic of air

[Term]
id: ENVO:09200002
name: environmental system process quality
def: "The quality of a environmental system process." []
synonym: "quality of environmental system process" EXACT []
is_a: PATO:0001236 ! process quality
intersection_of: PATO:0001236 ! process quality
intersection_of: RO:0000052 ENVO:02500000 ! characteristic of environmental system process
relationship: RO:0000052 ENVO:02500000 ! characteristic of environmental system process

[Term]
id: ENVO:09200004
name: porosity of soil
def: "The porosity of some soil." []
synonym: "soil porosity" EXACT []
is_a: ENVO:09200009 ! structure of soil
is_a: PATO:0000973 ! porosity
intersection_of: PATO:0000973 ! porosity
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200005
name: mass density of soil
def: "The mass density of some soil." []
synonym: "soil mass density" EXACT []
is_a: PATO:0001019 ! mass density
intersection_of: PATO:0001019 ! mass density
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200006
name: concentration of ammonium in soil
def: "The concentration of a ammonium when measured in soil." []
synonym: "soil ammonium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09200007
name: concentration of nitrate in soil
def: "The concentration of a nitrate when measured in soil." []
synonym: "soil nitrate concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:09200008
name: composition of soil
def: "The composition of some soil." []
synonym: "soil composition" EXACT []
is_a: ENVO:09200009 ! structure of soil
is_a: PATO:0000025 ! composition
intersection_of: PATO:0000025 ! composition
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200009
name: structure of soil
def: "The structure of some soil." []
synonym: "soil structure" EXACT []
is_a: PATO:0000141 ! structure
intersection_of: PATO:0000141 ! structure
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200010
name: acidity of soil
def: "The acidity of some soil." []
synonym: "soil acidity" EXACT []
is_a: PATO:0001842 ! acidity
intersection_of: PATO:0001842 ! acidity
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200011
name: pressure of air
def: "The pressure of some air." []
synonym: "air pressure" EXACT []
is_a: PATO:0001025 ! pressure
intersection_of: PATO:0001025 ! pressure
intersection_of: RO:0000052 ENVO:00002005 ! characteristic of air
relationship: RO:0000052 ENVO:00002005 ! characteristic of air

[Term]
id: ENVO:09200012
name: temperature of soil
def: "The temperature of some soil." []
synonym: "soil temperature" EXACT []
is_a: ENVO:09200000 ! temperature of environmental material
intersection_of: PATO:0000146 ! temperature
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200013
name: wetness of soil
def: "The wetness of some soil." []
synonym: "soil wetness" EXACT []
is_a: PATO:0001822 ! wetness
intersection_of: PATO:0001822 ! wetness
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200014
name: temperature of water
def: "The temperature of some water." []
synonym: "water temperature" EXACT []
is_a: ENVO:09200000 ! temperature of environmental material
intersection_of: PATO:0000146 ! temperature
intersection_of: RO:0000052 ENVO:00002006 ! characteristic of liquid water
relationship: RO:0000052 ENVO:00002006 ! characteristic of liquid water

[Term]
id: ENVO:09200015
name: humidity of soil
def: "The humidity of some soil." []
synonym: "soil humidity" EXACT []
is_a: PATO:0015009 ! humidity
intersection_of: PATO:0015009 ! humidity
intersection_of: RO:0000052 ENVO:00001998 ! characteristic of soil
relationship: RO:0000052 ENVO:00001998 ! characteristic of soil

[Term]
id: ENVO:09200017
name: composition of water
def: "The composition of some water." []
synonym: "water composition" EXACT []
is_a: PATO:0000025 ! composition
intersection_of: PATO:0000025 ! composition
intersection_of: RO:0000052 ENVO:00002006 ! characteristic of liquid water
relationship: RO:0000052 ENVO:00002006 ! characteristic of liquid water

[Term]
id: ENVO:09200020
name: concentration of nitrate in groundwater
def: "The concentration of a nitrate when measured in groundwater." []
synonym: "ground water nitrate concentration" EXACT []
is_a: ENVO:3100022 ! concentration of nitrate in liquid water

[Term]
id: ENVO:09200033
name: pressure of atmospheric water vapour
def: "The pressure of some atmospheric water vapour." []
synonym: "atmospheric water vapour pressure" EXACT []
is_a: PATO:0001025 ! pressure
intersection_of: PATO:0001025 ! pressure
intersection_of: RO:0000052 ENVO:01000268 ! characteristic of atmospheric water vapour
relationship: RO:0000052 ENVO:01000268 ! characteristic of atmospheric water vapour

[Term]
id: ENVO:09200034
name: porosity of snow
def: "The porosity of some snow." []
synonym: "snow porosity" EXACT []
is_a: PATO:0000973 ! porosity
intersection_of: PATO:0000973 ! porosity
intersection_of: RO:0000052 ENVO:01000406 ! characteristic of snow
relationship: RO:0000052 ENVO:01000406 ! characteristic of snow

[Term]
id: ENVO:09200035
name: porosity of water ice
def: "The porosity of some water ice." []
synonym: "water ice porosity" EXACT []
is_a: PATO:0000973 ! porosity
intersection_of: PATO:0000973 ! porosity
intersection_of: RO:0000052 ENVO:01000277 ! characteristic of water ice
relationship: RO:0000052 ENVO:01000277 ! characteristic of water ice

[Term]
id: ENVO:09200036
name: mass density of snow
def: "The mass density of some snow." []
synonym: "snow mass density" EXACT []
is_a: PATO:0001019 ! mass density
intersection_of: PATO:0001019 ! mass density
intersection_of: RO:0000052 ENVO:01000406 ! characteristic of snow
relationship: RO:0000052 ENVO:01000406 ! characteristic of snow

[Term]
id: ENVO:1000745
name: drought
def: "A hydrological precipitation process with a reduced rate relative to some historical average, typically resulting in ecosystemic perturbations." []
is_a: ENVO:01000703 ! hydrological precipitation process

[Term]
id: ENVO:2000000
name: chemical product
def: "A manufactured product that is some mixture of chemicals created through some chemical engineering process" [https://orcid.org/0000-0002-6601-2165]
is_a: ENVO:00003074 ! manufactured product

[Term]
id: ENVO:2000001
name: creosote
def: "The portion of chemical products obtained by the distillation of a tar that remains heavier than water, notably useful for its anti-septic and preservative properties" [https://en.wikipedia.org/wiki/Creosote]
xref: https://en.wikipedia.org/wiki/Creosote
is_a: ENVO:2000000 ! chemical product

[Term]
id: ENVO:2000002
name: industrial wastewate treatment plant
def: "A wastewater treatment plant that treates industrial wastewater. Industrial wastewater treatment covers the mechanisms and processes used to treat waters that have been contaminated in some way by anthropogenic industrial or commercial activities prior to its release into the environment or its re-use." [https://en.wikipedia.org/wiki/Industrial_wastewater_treatment]
is_a: ENVO:00002043 ! wastewater treatment plant

[Term]
id: ENVO:2000003
name: agricultural wastewater treatment plant
def: "A wastewater treatment plant that treats agriculatural wastewater. Agricultural wastewater treatment relates to the treatment of wastewaters produced in the course of agricultural activities. Agriculture is a highly intensified industry in many parts of the world, producing a range of wastewaters requiring a variety of treatment technologies and management practices." [https://en.wikipedia.org/wiki/Agricultural_wastewater_treatment]
is_a: ENVO:00002043 ! wastewater treatment plant

[Term]
id: ENVO:2000004
name: algal bloom
def: "A feature that arises from a rapid increase or accumulation in the population of algae (typically microscopic) in an aquatic system." [https://en.wikipedia.org/wiki/Algal_bloom]
xref: EcoLexicon:algal_bloom
xref: https://en.wikipedia.org/wiki/Algal_bloom
xref: SWEETRealm:AlgalBloom
is_a: ENVO:00000012 ! hydrographic feature

[Term]
id: ENVO:2000005
name: freshwater algal bloom
def: "An algal bloom that is located in freshwater. Freshwater algal blooms are the result of an excess of nutrients, particularly some phosphates." [https://en.wikipedia.org/wiki/Algal_bloom#Freshwater_algal_blooms]
is_a: ENVO:2000004 ! algal bloom
intersection_of: ENVO:2000004 ! algal bloom
intersection_of: RO:0001025 ENVO:00000873 ! located in freshwater biome
relationship: RO:0001025 ENVO:00000873 ! located in freshwater biome

[Term]
id: ENVO:2000012
name: anthropogenic generation of energy
def: "The generation of energy for use by humans" []
is_a: ENVO:02500027 ! anthropogenic environmental process
intersection_of: ENVO:02500027 ! anthropogenic environmental process
intersection_of: ENVO:2000036 ENVO:2000015 ! generates energy
relationship: ENVO:2000036 ENVO:2000015 ! generates energy

[Term]
id: ENVO:2000013
name: generation of energy from coal
is_a: ENVO:2000012 ! anthropogenic generation of energy
intersection_of: ENVO:2000012 ! anthropogenic generation of energy
intersection_of: RO:0002233 ENVO:02000091 ! has input coal
relationship: RO:0002233 ENVO:02000091 ! has input coal

[Term]
id: ENVO:2000014
name: generation of energy from oil
is_a: ENVO:2000012 ! anthropogenic generation of energy
intersection_of: ENVO:2000012 ! anthropogenic generation of energy
intersection_of: RO:0002233 ENVO:00002985 ! has input oil
relationship: RO:0002233 ENVO:00002985 ! has input oil

[Term]
id: ENVO:2000015
name: energy
def: "A disposition which is realized during the execution of work, the emission of heat, or the possession of mass." []
comment: Consider replacing with PATO class; note that PATO class is not a disposition. This should likely go into OBO Core and also have a physicist look at it.
is_a: BFO:0000016 ! disposition

[Term]
id: ENVO:2000016
name: potential energy
def: "Energy possessed by an object because of its position relative to other objects, stresses within itself, its electric charge, or other factors." []
is_a: ENVO:2000015 ! energy

[Term]
id: ENVO:2000017
name: kinetic energy
def: "Energy which is realised through motion." []
is_a: ENVO:2000015 ! energy

[Term]
id: ENVO:2000018
name: mixed potential and kinetic energy
def: "Energy which is the sum of 1) kinetic energy and 2) potential energy." []
is_a: ENVO:2000015 ! energy
intersection_of: ENVO:2000015 ! energy
intersection_of: BFO:0000051 ENVO:2000016 ! has part potential energy
intersection_of: BFO:0000051 ENVO:2000017 ! has part kinetic energy
relationship: BFO:0000051 ENVO:2000016 ! has part potential energy
relationship: BFO:0000051 ENVO:2000017 ! has part kinetic energy

[Term]
id: ENVO:2000025
name: nuclear energy
def: "potential energy that binds nucleons to form the atomic nucleus (and nuclear reactions)." []
is_a: ENVO:2000016 ! potential energy

[Term]
id: ENVO:2000030
name: radiant energy
def: "Potential energy which is stored in the fields of propagated by electromagnetic radiation." []
is_a: ENVO:2000016 ! potential energy
relationship: BFO:0000054 ENVO:01001026 ! realized in electromagnetic radiation

[Term]
id: ENVO:2000032
name: thermal energy
def: "Kinetic energy which is realised through the microscopic motion of particles." []
comment: A form of disordered mechanical energy.
is_a: ENVO:2000017 ! kinetic energy

[Term]
id: ENVO:2000034
name: geothermal energy
def: "Thermal energy which propagates through a solid (typically rocky) astronomical body." []
comment: Often, this term is used specifically for thermal energy spreading from heat sources (e.g. magma chambers, the planetary core) within the Earth. However, it is also used for extraterrestrial bodies.
is_a: ENVO:2000032 ! thermal energy

[Term]
id: ENVO:2000035
name: stellar radiation energy
is_a: ENVO:2000030 ! radiant energy

[Term]
id: ENVO:2000037
name: fossil fuel power plant
def: "A power station which burns a fossil fuel such as coal, natural gas, or petroleum to produce electricity." []
is_a: ENVO:00002214 ! power plant

[Term]
id: ENVO:2000038
name: coal power plant
is_a: ENVO:2000037 ! fossil fuel power plant

[Term]
id: ENVO:2000039
name: gas power station
is_a: ENVO:2000037 ! fossil fuel power plant

[Term]
id: ENVO:2000041
name: solar power station
is_a: ENVO:00002214 ! power plant

[Term]
id: ENVO:2000042
name: ocean thermal power station
synonym: "OTEC power plant" EXACT []
synonym: "OTEC power station" EXACT []
is_a: ENVO:00002214 ! power plant

[Term]
id: ENVO:2000045
name: hydrocarbon-based environmental material
is_a: ENVO:00010483 ! environmental material
intersection_of: ENVO:00010483 ! environmental material
intersection_of: RO:0002473 CHEBI:24632 ! composed primarily of hydrocarbon
relationship: RO:0000053 PATO:0015021 ! has characteristic combustibility
relationship: RO:0000087 CHEBI:33292 ! has role fuel
relationship: RO:0002473 CHEBI:24632 ! composed primarily of hydrocarbon

[Term]
id: ENVO:2000046
name: oxygen cycling
def: "A biogeochemical cycle which has oxygen as participant." []
synonym: "global carbon cycling" EXACT []
is_a: ENVO:02500009 ! biogeochemical cycling
intersection_of: ENVO:02500009 ! biogeochemical cycling
intersection_of: RO:0002233 CHEBI:25806 ! has input oxygen molecular entity
relationship: RO:0002233 CHEBI:25806 ! has input oxygen molecular entity

[Term]
id: ENVO:2100000
name: anatomical entity environment
def: "An environment which is determined by an anatomical entity." []
is_a: ENVO:01000254 ! environmental system
intersection_of: ENVO:01000254 ! environmental system
intersection_of: RO:0002509 UBERON:0001062 ! determined by part of anatomical entity
relationship: BFO:0000050 ENVO:01001000 ! part of environmental system determined by an organism
relationship: RO:0002509 UBERON:0001062 ! determined by part of anatomical entity

[Term]
id: ENVO:2100002
name: intestine environment
def: "An environmental system determined by an intestine." []
is_a: ENVO:01001033 ! digestive tract environment
intersection_of: ENVO:2100000 ! anatomical entity environment
intersection_of: RO:0002507 UBERON:0000160 ! determined by intestine
relationship: RO:0002507 UBERON:0000160 ! determined by intestine

[Term]
id: ENVO:2100003
name: skin environment
def: "An environment determined by an area or zone of skin tissue." []
is_a: ENVO:01000997 ! environmental system determined by a quality
is_a: ENVO:2100000 ! anatomical entity environment
intersection_of: ENVO:2100000 ! anatomical entity environment
intersection_of: RO:0002507 UBERON:0000014 ! determined by zone of skin
relationship: RO:0002507 UBERON:0000014 ! determined by zone of skin

[Term]
id: ENVO:2100004
name: integumental system environment
is_a: ENVO:2100000 ! anatomical entity environment
intersection_of: ENVO:2100000 ! anatomical entity environment
intersection_of: RO:0002509 UBERON:0002416 ! determined by part of integumental system
relationship: RO:0002509 UBERON:0002416 ! determined by part of integumental system

[Term]
id: ENVO:2100005
name: face skin environment
is_a: ENVO:2100003 ! skin environment
intersection_of: ENVO:2100000 ! anatomical entity environment
intersection_of: RO:0002507 UBERON:1000021 ! determined by skin of face
relationship: RO:0002507 UBERON:1000021 ! determined by skin of face

[Term]
id: ENVO:21001212
name: microwave radiation
def: "A radiation process during which electromagnetic waves or their quanta are emitted at wavelengths and frequencies which travel exclusively in a line-of-sight fashion and which may produce molecular rotation and torsion on contact with matter." [https://en.wikipedia.org/wiki/Microwave, https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
comment: This definition focuses on the properties of microwaves rather than their wavelength or frequency limits. Considerable ambiguity exists around the wavelength and frequency thresholds of microwaves. The ISO 21348 definition bounds these waves at 1 mm and 15 mm, with frequencies between 100 GHz and 0.225 GHz.
xref: NCIT:C16862
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:21001213
name: radio wave radiation
def: "A radiation process during which electromagnetic waves or their quanta are emitted at wavelengths ranging from millimetre to kilometer scales." [https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
comment: As with microwaves, considerable variation exists in the delimitation of frequency and wavelength thresholds for radiowaves. The ISO 21348 standard allows a wavelength range of 0.10 mm to 100 m and a frequency range of 300 GHz to 3 MHz. However, much lower thresholds also exist.
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:21001214
name: infrared radiation
def: "A radiation process during which electromagnetic waves or their quanta are emitted when molecules change their rotational-vibrational movements, usually at wavelengths between 760 nm and 1 mm." [https://en.wikipedia.org/wiki/Infrared, https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
synonym: "infra-red radiation" EXACT []
xref: NCIT:C16736
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:21001215
name: visible spectrum radiation
def: "A radiation process during which electromagnetic waves or their quanta are emitted at wavelengths between 380 nm and 760 nm." [https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
synonym: "optical radiation" EXACT []
xref: NCIT:C17732
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:21001216
name: ultraviolet radiation
def: "A radiation process during which electromagnetic waves or their quanta are emitted at wavelengths between 10 nm and 400 nm." [https://en.wikipedia.org/wiki/Ultraviolet, https://www.iso.org/obp/ui/#iso\:std\:iso\:21348]
synonym: "UV radiation" EXACT []
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:21001217
name: X-ray radiation
def: "A radiation process during which penetrating electromagnetic radiation is emitted by high-energy electrons as they fall into a lower state of energy." [https://en.wikipedia.org/wiki/X-ray]
synonym: "X ray radiation" EXACT []
xref: NCIT:C17262
is_a: ENVO:21001219 ! ionizing radiation

[Term]
id: ENVO:21001218
name: gamma-ray radiation
def: "A radiation process during which penetrating electromagnetic radiation is emitted from the radioactive decay (gamma decay) of atomic nuclei." [https://en.wikipedia.org/wiki/Gamma_ray]
is_a: ENVO:21001219 ! ionizing radiation

[Term]
id: ENVO:21001219
name: ionizing radiation
def: "A radiation process during which electromagnetic waves or their quanta are emitted with sufficient energy to disrupt molecular bonds or alter the electron number of atoms." [https://en.wikipedia.org/wiki/Electromagnetic_radiation]
synonym: "ionising radiation" EXACT []
xref: NCIT:C17052
is_a: ENVO:01001026 ! electromagnetic radiation

[Term]
id: ENVO:3100001
name: concentration of Adenosine 5-triphosphate in liquid water
def: "The concentration of Adenosine 5-triphosphate when measured in liquid water." []
synonym: "liquid water Adenosine 5-triphosphate concentration" EXACT []
is_a: ENVO:3100026 ! concentration of phosphate in liquid water

[Term]
id: ENVO:3100004
name: concentration of ammonium in liquid water
def: "The concentration of ammonium when measured in liquid water." []
synonym: "liquid water ammonium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100006
name: concentration of beta-carotene in liquid water
def: "The concentration of beta-carotene when measured in liquid water." []
synonym: "liquid water beta-carotene concentration" EXACT []
is_a: ENVO:3100007 ! concentration of carotene in liquid water

[Term]
id: ENVO:3100007
name: concentration of carotene in liquid water
def: "The concentration of carotene when measured in liquid water." []
synonym: "liquid water carotene concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100011
name: concentration of dioxygen in liquid water
def: "The concentration of dioxygen when measured in liquid water." []
synonym: "liquid water dioxygen concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100016
name: concentration of hydrogen peroxide in liquid water
def: "The concentration of hydrogen peroxide when measured in liquid water." []
synonym: "liquid water hydrogen peroxide concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100017
name: concentration of hydrogen sulfide in liquid water
def: "The concentration of hydrogen sulfide when measured in liquid water." []
synonym: "liquid water hydrogen sulfide concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100020
name: concentration of methane in liquid water
def: "The concentration of methane when measured in liquid water." []
synonym: "liquid water methane concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100022
name: concentration of nitrate in liquid water
def: "The concentration of nitrate when measured in liquid water." []
synonym: "liquid water nitrate concentration" EXACT []
is_a: ENVO:03000123 ! concentration of nitrate and nitrite in liquid water

[Term]
id: ENVO:3100023
name: concentration of nitrite in liquid water
def: "The concentration of nitrite when measured in liquid water." []
synonym: "liquid water nitrite concentration" EXACT []
is_a: ENVO:03000123 ! concentration of nitrate and nitrite in liquid water

[Term]
id: ENVO:3100024
name: concentration of nitrous oxide in liquid water
def: "The concentration of nitrous oxide when measured in liquid water." []
synonym: "liquid water nitrous oxide concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100026
name: concentration of phosphate in liquid water
def: "The concentration of phosphate when measured in liquid water." []
synonym: "liquid water phosphate concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100030
name: acidity of water
def: "The acidity of some water." []
synonym: "water acidity" EXACT []
is_a: PATO:0001842 ! acidity
intersection_of: PATO:0001842 ! acidity
intersection_of: RO:0000052 ENVO:00002006 ! characteristic of liquid water
relationship: RO:0000052 ENVO:00002006 ! characteristic of liquid water

[Term]
id: ENVO:3100033
name: pressure of water
def: "The pressure of some water." []
synonym: "water pressure" EXACT []
is_a: PATO:0001025 ! pressure
intersection_of: PATO:0001025 ! pressure
intersection_of: RO:0000052 ENVO:00002006 ! characteristic of liquid water
relationship: RO:0000052 ENVO:00002006 ! characteristic of liquid water

[Term]
id: ENVO:3100037
name: concentration of nitrate in sea water
def: "The concentration of nitrate when measured in sea water." []
synonym: "sea water nitrate concentration" EXACT []
is_a: ENVO:3100022 ! concentration of nitrate in liquid water

[Term]
id: ENVO:3100038
name: concentration of phosphate in sea water
def: "The concentration of phosphate when measured in sea water." []
synonym: "sea water phosphate concentration" EXACT []
is_a: ENVO:3100026 ! concentration of phosphate in liquid water

[Term]
id: ENVO:3100040
name: concentration of ammonium in sea water
def: "The concentration of ammonium when measured in sea water." []
synonym: "sea water ammonium concentration" EXACT []
is_a: ENVO:3100004 ! concentration of ammonium in liquid water

[Term]
id: ENVO:3100041
name: concentration of nitrite in sea water
def: "The concentration of nitrite when measured in sea water." []
synonym: "sea water nitrite concentration" EXACT []
is_a: ENVO:3100023 ! concentration of nitrite in liquid water

[Term]
id: ENVO:3100043
name: concentration of carbon atom in sea water
def: "The concentration of carbon atom when measured in sea water." []
synonym: "sea water carbon atom concentration" EXACT []
is_a: ENVO:09000009 ! concentration of carbon atom in water

[Term]
id: ENVO:3100044
name: concentration of chloroflurocarbon in sea water
def: "The concentration of chloroflurocarbon when measured in sea water." []
synonym: "sea water chloroflurocarbon concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100048
name: concentration of sulfur hexafluoride in sea water
def: "The concentration of sulfur hexafluoride when measured in sea water." []
synonym: "sea water sulfur hexafluoride concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100049
name: concentration of calcium carbonate in sea water
def: "The concentration of calcium carbonate when measured in sea water." []
synonym: "sea water calcium carbonate concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3100060
name: concentration of dioxygen in sea water
def: "The concentration of dioxygen when measured in sea water." []
synonym: "sea water dioxygen concentration" EXACT []
is_a: ENVO:3100011 ! concentration of dioxygen in liquid water

[Term]
id: ENVO:3200021
name: concentration of bromine in water ice
def: "The concentration of bromine when measured in water ice." []
synonym: "water ice bromine concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200023
name: concentration of cobalt in water ice
def: "The concentration of cobalt when measured in water ice." []
synonym: "water ice cobalt concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200026
name: concentration of gadolinium in water ice
def: "The concentration of gadolinium when measured in water ice." []
synonym: "water ice gadolinium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200028
name: concentration of lithium in water ice
def: "The concentration of lithium when measured in water ice." []
synonym: "water ice lithium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200029
name: concentration of methanesulfonic acid in water ice
def: "The concentration of methanesulfonic acid when measured in water ice." []
synonym: "water ice methanesulfonic acid concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200030
name: concentration of molybdenum in water ice
def: "The concentration of molybdenum when measured in water ice." []
synonym: "water ice molybdenum concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200035
name: concentration of silver in water ice
def: "The concentration of silver when measured in water ice." []
synonym: "water ice silver concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200036
name: concentration of thallium in water ice
def: "The concentration of thallium when measured in water ice." []
synonym: "water ice thallium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200037
name: concentration of tin in water ice
def: "The concentration of tin when measured in water ice." []
synonym: "water ice tin concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200038
name: concentration of titanium in water ice
def: "The concentration of titanium when measured in water ice." []
synonym: "water ice titanium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200040
name: concentration of bromine in snow
def: "The concentration of bromine when measured in snow." []
synonym: "snow bromine concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200042
name: concentration of cobalt in snow
def: "The concentration of cobalt when measured in snow." []
synonym: "snow cobalt concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200045
name: concentration of gadolinium in snow
def: "The concentration of gadolinium when measured in snow." []
synonym: "snow gadolinium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200047
name: concentration of lithium in snow
def: "The concentration of lithium when measured in snow." []
synonym: "snow lithium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200048
name: concentration of methanesulfonic acid in snow
def: "The concentration of methanesulfonic acid when measured in snow." []
synonym: "snow methanesulfonic acid concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200049
name: concentration of molybdenum in snow
def: "The concentration of molybdenum when measured in snow." []
synonym: "snow molybdenum concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200054
name: concentration of silver in snow
def: "The concentration of silver when measured in snow." []
synonym: "snow silver concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200055
name: concentration of thallium in snow
def: "The concentration of thallium when measured in snow." []
synonym: "snow thallium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200056
name: concentration of tin in snow
def: "The concentration of tin when measured in snow." []
synonym: "snow tin concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200057
name: concentration of titanium in snow
def: "The concentration of titanium when measured in snow." []
synonym: "snow titanium concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200059
name: concentration of urea in liquid water
def: "The concentration of urea when measured in liquid water." []
synonym: "liquid water urea concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200060
name: concentration of oxygen in soil
def: "The concentration of oxygen when measured in soil." []
synonym: "soil oxygen concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200061
name: concentration of manganese molecular entity in soil
def: "The concentration of manganese molecular entity when measured in soil." []
synonym: "soil manganese molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200062
name: concentration of iron molecular entity in soil
def: "The concentration of iron molecular entity when measured in soil." []
synonym: "soil iron molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200063
name: concentration of aluminium molecular entity in soil
def: "The concentration of aluminium molecular entity when measured in soil." []
synonym: "soil aluminium molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200064
name: concentration of magnesium molecular entity in soil
def: "The concentration of magnesium molecular entity when measured in soil." []
synonym: "soil magnesium molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200065
name: concentration of sodium molecular entity in soil
def: "The concentration of sodium molecular entity when measured in soil." []
synonym: "soil sodium molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200066
name: concentration of organic nitrogen anion in soil
def: "The concentration of organic nitrogen anion when measured in soil." []
synonym: "soil organic nitrogen anion concentration" EXACT []
is_a: ENVO:3200071 ! concentration of organic molecular entity in soil

[Term]
id: ENVO:3200067
name: concentration of organophosphorus compound in soil
def: "The concentration of organophosphorus compound when measured in soil." []
synonym: "soil organophosphorus compound concentration" EXACT []
is_a: ENVO:3200068 ! concentration of phosphorus molecular entity in soil
is_a: ENVO:3200071 ! concentration of organic molecular entity in soil

[Term]
id: ENVO:3200068
name: concentration of phosphorus molecular entity in soil
def: "The concentration of phosphorus molecular entity when measured in soil." []
synonym: "soil phosphorus molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200069
name: concentration of potassium molecular entity in soil
def: "The concentration of potassium molecular entity when measured in soil." []
synonym: "soil potassium molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200070
name: concentration of calcium carbonate in soil
def: "The concentration of calcium carbonate when measured in soil." []
synonym: "soil calcium carbonate concentration" EXACT []
is_a: ENVO:09000027 ! concentration of salt in soil
is_a: ENVO:3200071 ! concentration of organic molecular entity in soil

[Term]
id: ENVO:3200071
name: concentration of organic molecular entity in soil
def: "The concentration of organic molecular entity when measured in soil." []
synonym: "soil organic molecular entity concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ENVO:3200073
name: concentration of sulfate in soil
def: "The concentration of sulfate when measured in soil." []
synonym: "soil sulfate concentration" EXACT []
is_a: PATO:0000033 ! concentration of

[Term]
id: ExO:0000000
name: exposure stressor
def: "An agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure_receptor during an exposure event." [CTD:curators]
is_a: BFO:0000040 ! material entity
relationship: interacts_with_an_exposure_receptor_via ExO:0000002 ! exposure event
relationship: RO:0002434 ExO:0000001 ! interacts with exposure recipient

[Term]
id: ExO:0000001
name: exposure recipient
def: "An entity (e.g., a human, human population, or a human organ) that interacts with an exposure stimulus during an exposure event." [CTD:curators]
synonym: "exposure receptor" EXACT []
synonym: "exposure target" EXACT []
is_a: BFO:0000040 ! material entity
relationship: RO:0002434 ExO:0000000 ! interacts with exposure stressor

[Term]
id: ExO:0000002
name: exposure event
def: "An interaction between an exposure stressor and an exposure_receptor." [CTD:curators]
is_a: BFO:0000015 ! process
relationship: BFO:0000051 ExO:0000000 ! has part exposure stressor
relationship: BFO:0000051 ExO:0000001 ! has part exposure recipient
relationship: interacts_with_an_exposure_receptor_via ExO:0000000 ! exposure stressor
relationship: interacts_with_an_exposure_stressor_via ExO:0000001 ! exposure recipient

[Term]
id: ExO:0000055
name: exposure route
def: "The way people, sample, or other living organisms come into contact with a stressor." [CTD:curators]
relationship: BFO:0000050 ExO:0000002 ! part of exposure event

[Term]
id: ExO:0000056
name: ingestion route
def: "An exposure route in which a subject or sample comes in contact with a stressor by swallowing the stressor or a substance containing the stressor." [https://orcid.org/0000-0002-4142-7153]
is_a: ExO:0000165 ! gastrointestinal tract route

[Term]
id: ExO:0000057
name: inhalation route
def: "An exposure route in which a subject or sample comes in contact with a stressor through breathing." [https://orcid.org/0000-0002-4142-7153]
is_a: ExO:0000055 ! exposure route

[Term]
id: ExO:0000060
name: injection route
def: "An exposure route in which a subject or sample comes in contact with a stressor that has directly entered the body through punctures, bites, or needles." [https://orcid.org/0000-0002-4142-7153]
is_a: ExO:0000055 ! exposure route

[Term]
id: ExO:0000159
name: maternal
def: "A route by which an exposure to a pregnant female causes an outcome in the fetus that might be observed long after birth" []
is_a: ExO:0000055 ! exposure route

[Term]
id: ExO:0000165
name: gastrointestinal tract route
def: "An exposure route in which a subject or sample comes in contact with a stressor in the subject's gastrointestinal tract." [https://orcid.org/0000-0002-4142-7153]
is_a: ExO:0000055 ! exposure route

[Term]
id: FOODON:00001002
name: food product
def: "Food material for humans and animals which is processed with the intention that it be consumable as a whole or added to other food products." []
comment: The FoodOn "food product"class is provided as a branch under which new food product categories and food products themselves can be placed. Here classes are provided to differentiate a food product by its food composition, processing and/or consumption characteristics. This avoids brand name products but it may include generic food dish categories. It has a much greater depth and polyhierarchy than other agency product type schemes have in an effort to group related products together.  The upper level basis of this tree originated in the environment ontology (ENVO) and from the US Code of Federal Regulations.
is_a: FOODON:00002403 ! food material

[Term]
id: FOODON:00001006
name: mammalian meat food product
def: "A food product made of meat, the skeletal muscle and associated fat, and other edible tissues such as organs, livers, skin, brains, bone marrow, kidneys, or lungs, of mammals." []
xref: https://bioregistry.io/reference/siren\:F17332
is_a: FOODON:00001092 ! vertebrate food product
is_a: FOODON:00005501 ! mammal material
relationship: RO:0001000 FOODON:03411134 ! derives from mammal
relationship: RO:0002350 FOODON:03400150 ! member of meat or meat product (from mammal) (us cfr)

[Term]
id: FOODON:00001007
name: meat sausage food product
def: "A processed meat food product that is made from a sausage." []
is_a: FOODON:00001010 ! processed meat food product
relationship: RO:0002350 FOODON:03400221 ! member of sausage or luncheon meat (us cfr)

[Term]
id: FOODON:00001009
name: hot dog
def: "A hot dog is a moist sausage of soft, even texture and flavor, often made from advanced meat recovery or meat slurry. Most types are fully cooked, cured or smoked. It is often placed hot in a special purpose soft, sliced hot dog bun." []
synonym: "hotdog" EXACT []
is_a: FOODON:00001224 ! meat sausage (cooked)

[Term]
id: FOODON:00001010
name: processed meat food product
def: "A processed food product consisting of meat which has been subjected to preservation and/or taste altering processes such as grinding, salting, curing, fermentation, smoking, and addition of chemical preservatives." []
is_a: FOODON:00001006 ! mammalian meat food product
is_a: FOODON:03311737 ! processed food
relationship: FOODON:00001563 FOODON:02010113 ! has defining ingredient piece of animal meat (boneless)

[Term]
id: FOODON:00001011
name: milk formula food product
is_a: FOODON:00001091 ! dried milk food product
relationship: RO:0002350 FOODON:03400274 ! member of meal replacement (us cfr)

[Term]
id: FOODON:00001013
name: cheese food product
def: "Cheese is a food derived from milk that is produced in a wide range of flavors, textures, and forms by coagulation of the milk protein casein." []
synonym: "cheese" EXACT []
xref: https://bioregistry.io/reference/siren\:F1076
xref: https://en.wikipedia.org/wiki/Cheese
is_a: FOODON:00001256 ! dairy food product
relationship: FOODON:00001563 FOODON:03420245 ! has defining ingredient mammalian milk curd
relationship: RO:0002350 FOODON:03400115 ! member of cheese or cheese product (us cfr)

[Term]
id: FOODON:00001014
name: yogurt food product
def: "A dairy product produced by bacterial fermentation of milk." []
comment: The bacteria used to make yogurt are known as yogurt cultures. The fermentation of lactose by these bacteria produces lactic acid, which acts on milk protein to give yogurt its texture and characteristic tart flavor.
synonym: "yoghourt" EXACT []
synonym: "yoghurt" EXACT []
synonym: "yougert" EXACT []
is_a: FOODON:00001053 ! fermented dairy food product

[Term]
id: FOODON:00001015
name: plant food product
def: "A food product which has as a defining ingredient some plant material." []
is_a: FOODON:00001002 ! food product
is_a: FOODON:00004331 ! plant material

[Term]
id: FOODON:00001016
name: cabbage food product
def: "Cabbage or headed cabbage (comprising several cultivars of Brassica oleracea) is a leafy green or purple biennial plant, grown as an annual vegetable crop for its dense-leaved heads." []
xref: https://en.wikipedia.org/wiki/Cabbage
is_a: FOODON:00001171 ! cruciferous inflorescence food product
is_a: FOODON:00003341 ! brassica food product
relationship: RO:0001000 NCBITaxon:3712 ! derives from Brassica oleracea

[Term]
id: FOODON:00001038
name: pork meat food product
def: "A food product made from domestic pig meat (Sus domesticus or Sus scrofa scrofa)." []
synonym: "pork" EXACT []
is_a: FOODON:00002663 ! pig food product
intersection_of: FOODON:00002663 ! pig food product
intersection_of: RO:0001000 FOODON:03302735 ! derives from pork meat (raw)
relationship: RO:0001000 FOODON:03302735 ! derives from pork meat (raw)

[Term]
id: FOODON:00001039
name: cured meat food product
def: "A meat that is preserved by the addition of a combination of salt, sugar, nitrates  or nitrite and or is smoked." [http://en.wikipedia.org/wiki/Cured_meat]
is_a: FOODON:00001010 ! processed meat food product
relationship: RO:0002350 FOODON:03400279 ! member of cured meat (us cfr)

[Term]
id: FOODON:00001040
name: chicken meat food product
def: "A food product that is derived from some chicken meat." []
is_a: FOODON:00001131 ! poultry meat food product
is_a: FOODON:02020149 ! chicken food product

[Term]
id: FOODON:00001041
name: cow food product
def: "A food product that is derived from some cow." []
is_a: FOODON:00001134 ! bovine meat food product
is_a: FOODON:02020889 ! cow material
intersection_of: FOODON:00001134 ! bovine meat food product
intersection_of: RO:0001000 NCBITaxon:9913 ! derives from Bos taurus
relationship: RO:0001000 NCBITaxon:9913 ! derives from Bos taurus

[Term]
id: FOODON:00001045
name: ice cream food product
def: "A frozen dessert usually made from dairy products, such as milk and cream, and often combined with fruits or other ingredients and flavours. Most varieties contain sugar, although some are made with other sweeteners. In some cases, artificial flavourings  and colourings are used in addition to (or in replacement of) the natural ingredients. This mixture is stirred slowly while cooling to prevent large ice crystals from forming; the result is a smoothly textured ice cream." [Wikipedia:Ice_cream]
synonym: "ice cream" EXACT []
synonym: "ice-cream" EXACT []
is_a: FOODON:00001149 ! confectionery food
is_a: FOODON:00001257 ! milk or milk based food product
is_a: FOODON:00001878 ! frozen dairy dessert
relationship: FOODON:00001563 FOODON:03420113 ! has defining ingredient mammalian milk or milk component
relationship: RO:0002350 FOODON:03400227 ! member of ice cream (us cfr)

[Term]
id: FOODON:00001046
name: animal seafood product
def: "A seafood product is a vertebrate or invertibrate organism from an aquatic environment." []
is_a: FOODON:00004242 ! animal food product
relationship: RO:0002350 FOODON:03400267 ! member of seafood or seafood product (us cfr)

[Term]
id: FOODON:00001053
name: fermented dairy food product
is_a: FOODON:00001256 ! dairy food product
is_a: FOODON:00001258 ! food (fermented)
intersection_of: FOODON:00001256 ! dairy food product
intersection_of: FOODON:00001258 ! food (fermented)

[Term]
id: FOODON:00001054
name: fermented fish or seafood food product
is_a: FOODON:00001055 ! sea water fish food product
is_a: FOODON:00001258 ! food (fermented)

[Term]
id: FOODON:00001055
name: sea water fish food product
is_a: FOODON:00001046 ! animal seafood product
is_a: FOODON:03315173 ! fish product (unspecified species)

[Term]
id: FOODON:00001056
name: flour food product
def: "A food product made from flour." []
is_a: FOODON:00004509 ! milled food product

[Term]
id: FOODON:00001057
name: plant fruit food product
def: "A food product derived from plant fruit." []
is_a: FOODON:00001261 ! vegetable food product
intersection_of: FOODON:00001261 ! vegetable food product
intersection_of: RO:0001000 FOODON:03411140 ! derives from fruit-producing plant
relationship: RO:0001000 FOODON:03411140 ! derives from fruit-producing plant
relationship: RO:0002350 FOODON:03400143 ! member of fruit or fruit product (us cfr)

[Term]
id: FOODON:00001059
name: apple juice
def: "Apple juice is a fruit juice made by the maceration and pressing of an apple." []
comment: SIREN DB annotation:\n* liquid, low viscosity, with no visible particles FOODON:03430123\n* fruit, peel present, core, pit or seed present FOODON:03420140
synonym: "apple juice" EXACT []
xref: https://bioregistry.io/reference/siren\:F1419
is_a: FOODON:00001140 ! fruit juice food product
is_a: FOODON:00001611 ! apple food product
intersection_of: FOODON:00001140 ! fruit juice food product
intersection_of: FOODON:00001611 ! apple food product

[Term]
id: FOODON:00001061
name: bacon food product
def: "Any of certain cuts of meat taken from the sides, belly or back of a pig that may be cured and/or smoked." []
is_a: FOODON:00001241 ! processed pork meat food product

[Term]
id: FOODON:00001069
name: fermented fruit food product
is_a: FOODON:00001258 ! food (fermented)
intersection_of: FOODON:00001258 ! food (fermented)
intersection_of: RO:0001000 FOODON:03315615 ! derives from fruit food product
relationship: RO:0001000 FOODON:03315615 ! derives from fruit food product

[Term]
id: FOODON:00001070
name: miso food product
def: "A food produced by fermenting rice, barley and/or soybeans, with salt and the mold koji-kin (Aspergillus oryzae)." []
comment: SIREN DB annotation:\n* semisolid FOODON:03430144\n* fully heat-treated FOODON:03440014\n* seed, skin present, germ present FOODON:03420133\n* fermentation/modification process, multiple component FOODON:03460128\n* salted FOODON:03460173\n* curing or aging process FOODON:03460253\n* preservation by fermentation FOODON:03470104
xref: https://bioregistry.io/reference/siren\:F1971
is_a: FOODON:00001078 ! fermented soybean food product
relationship: RO:0002350 FOODON:03400133 ! member of flavoring or seasoning (us cfr)

[Term]
id: FOODON:00001078
name: fermented soybean food product
def: "A food product having fermented soyabeans as a defining ingredient" []
is_a: FOODON:00002266 ! soybean food product
is_a: FOODON:03310006 ! fermented bean product

[Term]
id: FOODON:00001083
name: sugar condiment
is_a: FOODON:00001133 ! condiment
intersection_of: FOODON:00001133 ! condiment
intersection_of: RO:0001000 FOODON:03411012 ! derives from sugar-producing plant
relationship: RO:0001000 FOODON:03411012 ! derives from sugar-producing plant

[Term]
id: FOODON:00001087
name: vegetable oil food product
def: "A lipid material derived from plants. Physically, oils are liquid at room temperature." []
is_a: FOODON:03310387 ! oil
is_a: FOODON:03460263 ! vegetable fat or oil

[Term]
id: FOODON:00001088
name: flaxseed oil
def: "An oil used as a nutritional supplement and is a traditional European ethnic food, highly regarded for its nutty flavor." []
comment: Food-grade flaxseed oil is cold-pressed, obtained without solvent extraction, in the absence of oxygen, and marketed as edible flaxseed oil.[wikipedia]
synonym: "flax oil" EXACT []
synonym: "flax seed oil" EXACT []
synonym: "linseed oil" EXACT []
xref: langual:H0852
is_a: FOODON:00001859 ! flaxseed food product
is_a: FOODON:03420307 ! seed oil

[Term]
id: FOODON:00001091
name: dried milk food product
is_a: FOODON:00001257 ! milk or milk based food product
is_a: FOODON:03307539 ! food (dried)
intersection_of: FOODON:00001257 ! milk or milk based food product
intersection_of: FOODON:03307539 ! food (dried)

[Term]
id: FOODON:00001092
name: vertebrate food product
def: "A food product which is derived from or produced by an animal that has a vertibrae." []
is_a: FOODON:00004242 ! animal food product
is_a: FOODON:00005502 ! vertebrate material
intersection_of: FOODON:00004242 ! animal food product
intersection_of: RO:0001000 FOODON:03411297 ! derives from vertebrate animal
relationship: RO:0001000 FOODON:03411297 ! derives from vertebrate animal

[Term]
id: FOODON:00001093
name: cereal grain food product
is_a: FOODON:00001173 ! plant seed food product
intersection_of: FOODON:00001173 ! plant seed food product
intersection_of: RO:0001000 FOODON:03411324 ! derives from grain plant
relationship: RO:0001000 FOODON:03411324 ! derives from grain plant

[Term]
id: FOODON:00001094
name: fermented beverage
comment: SIREN DB annotation:\n* liquid FOODON:03430130\n* microbial/enzymatic modification process FOODON:03460119\n* curing or aging process FOODON:03460253
synonym: "alcoholic beverage" EXACT []
xref: https://bioregistry.io/reference/siren\:F5644
is_a: FOODON:00001258 ! food (fermented)
is_a: FOODON:03301977 ! beverage food product
intersection_of: FOODON:00001258 ! food (fermented)
intersection_of: FOODON:03301977 ! beverage food product

[Term]
id: FOODON:00001095
name: fermented grape beverage
is_a: FOODON:00001101 ! grape beverage
is_a: FOODON:00001254 ! plant derived fermented beverage
is_a: FOODON:03301444 ! vegetable juice food product
intersection_of: FOODON:00001101 ! grape beverage
intersection_of: FOODON:00001254 ! plant derived fermented beverage

[Term]
id: FOODON:00001100
name: orange fruit beverage
comment: SIREN DB annotation:\n* liquid, low viscosity FOODON:03430109\n* acidified FOODON:03460200\n* ingredient: water addition process FOODON:03460148\n* ingredient: sweetener added FOODON:03460202\n* ingredient: flavoring, spice or herb added FOODON:03460227
xref: https://bioregistry.io/reference/siren\:F2385
is_a: FOODON:00001156 ! citrus fruit juice
is_a: FOODON:00002071 ! orange food product
intersection_of: FOODON:00001156 ! citrus fruit juice
intersection_of: FOODON:00002071 ! orange food product
relationship: RO:0002350 FOODON:03400112 ! member of nonalcoholic beverage (us cfr)

[Term]
id: FOODON:00001101
name: grape beverage
is_a: FOODON:00001170 ! grape berry food product

[Term]
id: FOODON:00001107
name: bovine dairy food product
is_a: FOODON:00001256 ! dairy food product

[Term]
id: FOODON:00001109
name: caprine dairy food product
is_a: FOODON:00001107 ! bovine dairy food product

[Term]
id: FOODON:00001112
name: ovine dairy food product
is_a: FOODON:00001109 ! caprine dairy food product

[Term]
id: FOODON:00001118
name: cattle dairy food product
is_a: FOODON:00001107 ! bovine dairy food product
relationship: RO:0001000 FOODON:03411201 ! derives from dairy cow

[Term]
id: FOODON:00001126
name: bovine cheese food product
is_a: FOODON:00001013 ! cheese food product

[Term]
id: FOODON:00001127
name: cow milk cheese
is_a: FOODON:00001126 ! bovine cheese food product
is_a: FOODON:00001771 ! cow milk based food product
relationship: FOODON:00001563 FOODON:00004498 ! has defining ingredient cow milk curd
relationship: RO:0002350 FOODON:03400185 ! member of uncured cheese (us cfr)

[Term]
id: FOODON:00001131
name: poultry meat food product
def: "A food product made from domesticated bird meat." []
is_a: FOODON:00001283 ! poultry food product

[Term]
id: FOODON:00001132
name: swine food product
def: "Suidae is a family of artiodactyl mammals which are commonly called pigs, hogs or boars. In addition to numerous fossil species, 17 extant species are currently recognized (or 18 counting domestic pigs and wild boars separately), classified into between four and eight genera. The family includes the domestic pig, Sus scrofa domesticus or Sus domesticus, in addition to numerous species of wild pig, such as babirusas and warthogs. All suids, or swine, are native to the Old World, ranging from Asia to Europe and Africa." []
is_a: FOODON:00001006 ! mammalian meat food product
is_a: FOODON:00005689 ! swine material
intersection_of: FOODON:00001006 ! mammalian meat food product
intersection_of: RO:0001000 FOODON:03411136 ! derives from swine
relationship: RO:0001000 FOODON:03411136 ! derives from swine

[Term]
id: FOODON:00001133
name: condiment
def: "A relish, sauce, or seasoning  added to food to impart a particular flavour or to complement the dish." []
synonym: "condiment" EXACT []
xref: https://bioregistry.io/reference/siren\:F15708
is_a: FOODON:00001002 ! food product
relationship: RO:0002350 FOODON:03400179 ! member of condiment or relish (us cfr)

[Term]
id: FOODON:00001134
name: bovine meat food product
is_a: FOODON:00001006 ! mammalian meat food product
intersection_of: FOODON:00001006 ! mammalian meat food product
intersection_of: RO:0001000 FOODON:03414374 ! derives from bovine
relationship: RO:0001000 FOODON:03414374 ! derives from bovine

[Term]
id: FOODON:00001138
name: tea based beverage product
def: "A beverage product derived from leaves of the tea plant (Camellia sinensis)." []
comment: "While fermentation is also referred to in the production of brewed teas, this is inaccurate. Some herbal teas on the market today include probiotic cultures alongside tea leaves to maintain gut health but the tea itself hasn't been fermented. Most dried teas however don't use live cultures at all during production. Instead, harvested tea leaves undergo a natural chemical process known as oxidation, which also changes the color, flavor and level of health benefits in the resulting brew." [https://eatcultured.com/blogs/our-awesome-blog/fermented-tea]
is_a: FOODON:00001255 ! nonfermented plant derived beverage product
is_a: FOODON:00002275 ! steeped beverage product
intersection_of: FOODON:00002275 ! steeped beverage product
intersection_of: RO:0001000 NCBITaxon:4442 ! derives from Camellia sinensis
relationship: RO:0001000 NCBITaxon:4442 ! derives from Camellia sinensis

[Term]
id: FOODON:00001139
name: coffee based beverage product
synonym: "coffee and coffee products" EXACT []
is_a: FOODON:00001255 ! nonfermented plant derived beverage product
is_a: FOODON:00002275 ! steeped beverage product

[Term]
id: FOODON:00001140
name: fruit juice food product
is_a: FOODON:00001057 ! plant fruit food product
is_a: FOODON:00001255 ! nonfermented plant derived beverage product
is_a: FOODON:03301444 ! vegetable juice food product
is_a: FOODON:03315552 ! juice beverage
intersection_of: FOODON:00001057 ! plant fruit food product
intersection_of: FOODON:00001253 ! plant derived beverage
intersection_of: RO:0001000 FOODON:03420229 ! derives from fruit, peel removed, core, pit or seed removed
relationship: RO:0001000 FOODON:03420229 ! derives from fruit, peel removed, core, pit or seed removed
relationship: RO:0002350 FOODON:03400127 ! member of fruit juice (us cfr)

[Term]
id: FOODON:00001141
name: wheat food product
comment: SIREN DB annotation:\n* seed (anatomical part) FOODON:03420155
xref: https://bioregistry.io/reference/siren\:F10142
is_a: FOODON:00001093 ! cereal grain food product
relationship: RO:0001000 FOODON:03411312 ! derives from wheat plant

[Term]
id: FOODON:00001142
name: maize (corn) food product
def: "A food product deriving primarily from corn (maize)." []
synonym: "maize food product" EXACT []
is_a: FOODON:00001015 ! plant food product
intersection_of: FOODON:00001015 ! plant food product
intersection_of: RO:0001000 FOODON:03411232 ! derives from Zia mays plant
relationship: RO:0001000 FOODON:03411232 ! derives from Zia mays plant

[Term]
id: FOODON:00001146
name: solanaceous root food product
synonym: "tuber" EXACT []
is_a: FOODON:00001147 ! plant root food product
is_a: FOODON:00001165 ! solanaceous food product

[Term]
id: FOODON:00001147
name: plant root food product
def: "A food product derived from or produced by a plant root." []
is_a: FOODON:00001015 ! plant food product

[Term]
id: FOODON:00001148
name: potato food product
def: "A potato food product is any product derived from potatoes." []
is_a: FOODON:00001146 ! solanaceous root food product
intersection_of: FOODON:00001146 ! solanaceous root food product
intersection_of: RO:0001000 FOODON:03315354 ! derives from potato
relationship: RO:0001000 FOODON:03315354 ! derives from potato
relationship: RO:0002350 FOODON:03400152 ! member of vegetable or vegetable product (us cfr)

[Term]
id: FOODON:00001149
name: confectionery food
def: "Food items that are rich in sugar, any one or type of which is called a confection. Modern usage may include substances rich in artificial sweeteners as well." []
is_a: FOODON:00002373 ! food by meal type

[Term]
id: FOODON:00001150
name: cucurbit fruit food product
is_a: FOODON:00001057 ! plant fruit food product

[Term]
id: FOODON:00001151
name: citrus fruit food product
def: "A citrus fruit is botanically classified as a type of berry called a hesperidium that has a thick, leathery rind, with numerous oil glands, and a large flesh portion composed of several wedge-shaped sections. Unlike pome fruit, such as the apple, the citrus fruit is derived from a superior ovary, an ovary completely separate from the calyx." []
is_a: FOODON:00001057 ! plant fruit food product

[Term]
id: FOODON:00001152
name: melon fruit food product
def: "The fleshy fruit (false berry) of a plant of the family Cucurbitaceae." []
is_a: FOODON:00002029 ! melon food product

[Term]
id: FOODON:00001153
name: muskmelon (Cucumis melo) fruit food product
is_a: FOODON:00001152 ! melon fruit food product

[Term]
id: FOODON:00001154
name: citrullus lanatus fruit food product
def: "Citrullus lanatus is a plant species in the family Cucurbitaceae, a vine-like (scrambler and trailer) flowering plant originally from sub-Saharan Africa. It is cultivated for its fruit. The subdivision of this species into two varieties, watermelons (Citrullus lanatus (Thunb.) var. lanatus) and citron melons (Citrullus lanatus var. citroides (L. H. Bailey) Mansf.)" []
is_a: FOODON:00001152 ! melon fruit food product

[Term]
id: FOODON:00001156
name: citrus fruit juice
is_a: FOODON:00001140 ! fruit juice food product
is_a: FOODON:00001151 ! citrus fruit food product
intersection_of: FOODON:00001140 ! fruit juice food product
intersection_of: FOODON:00001151 ! citrus fruit food product

[Term]
id: FOODON:00001158
name: pomaceous fruit food product
synonym: "pomes" EXACT []
is_a: FOODON:00001057 ! plant fruit food product

[Term]
id: FOODON:00001163
name: solanaceous fruit food product
is_a: FOODON:00001057 ! plant fruit food product
is_a: FOODON:00001165 ! solanaceous food product

[Term]
id: FOODON:00001164
name: tomato food product
def: "A food product deriving from one or more tomatoes." []
is_a: FOODON:00001163 ! solanaceous fruit food product
is_a: FOODON:00002141 ! plant fruit as vegetable food product
relationship: RO:0001000 FOODON:03301453 ! derives from tomato

[Term]
id: FOODON:00001165
name: solanaceous food product
is_a: FOODON:00001015 ! plant food product

[Term]
id: FOODON:00001166
name: plant inflorescence food product
is_a: FOODON:00001015 ! plant food product

[Term]
id: FOODON:00001169
name: cruciferous food product
is_a: FOODON:00001015 ! plant food product

[Term]
id: FOODON:00001170
name: grape berry food product
is_a: FOODON:00001640 ! berry food product
intersection_of: FOODON:00001057 ! plant fruit food product
intersection_of: RO:0001000 FOODON:03411329 ! derives from grape cultivar
relationship: RO:0001000 FOODON:03411329 ! derives from grape cultivar

[Term]
id: FOODON:00001171
name: cruciferous inflorescence food product
is_a: FOODON:00001166 ! plant inflorescence food product
is_a: FOODON:00001169 ! cruciferous food product

[Term]
id: FOODON:00001172
name: nut food product
xref: https://bioregistry.io/reference/siren\:F16972
is_a: FOODON:00001262 ! botanical fruit food product
is_a: FOODON:03460177 ! plant seed or nut food product
relationship: RO:0001000 FOODON:03411213 ! derives from nut producing plant
relationship: RO:0002350 FOODON:03400260 ! member of nut or nut product (us cfr)

[Term]
id: FOODON:00001173
name: plant seed food product
is_a: FOODON:03460177 ! plant seed or nut food product

[Term]
id: FOODON:00001174
name: plant lipid food product
is_a: FOODON:00001015 ! plant food product
is_a: FOODON:00002664 ! lipid food product

[Term]
id: FOODON:00001175
name: plant stem food product
is_a: FOODON:00001015 ! plant food product

[Term]
id: FOODON:00001176
name: invertebrate food product
is_a: FOODON:00004242 ! animal food product
is_a: FOODON:00005522 ! invertebrate material
intersection_of: FOODON:00004242 ! animal food product
intersection_of: RO:0001000 FOODON:00002452 ! derives from invertebrate animal
relationship: RO:0001000 FOODON:00002452 ! derives from invertebrate animal

[Term]
id: FOODON:00001177
name: insect food product
def: "A food product with insects as a defining ingredient." []
is_a: FOODON:00001176 ! invertebrate food product
intersection_of: FOODON:00001176 ! invertebrate food product
intersection_of: RO:0001000 FOODON:03411220 ! derives from insect
relationship: RO:0001000 FOODON:03411220 ! derives from insect

[Term]
id: FOODON:00001178
name: honey food product
is_a: FOODON:00001218 ! bee food product
is_a: FOODON:00002300 ! sweetener
intersection_of: FOODON:00001218 ! bee food product
intersection_of: FOODON:00002300 ! sweetener
relationship: RO:0002350 FOODON:03400118 ! member of nutritive sweetener (us cfr)

[Term]
id: FOODON:00001180
name: prepared food product
def: "Food product that is 1) ready or nearly ready for consumption; 2) usually a composite of several foods or ingredients that often belong to distinct product types; 3) usually formulated, mixed and partially or fully cooked." []
is_a: FOODON:03311737 ! processed food
relationship: RO:0002350 FOODON:03400212 ! member of stew or hash (us cfr)

[Term]
id: FOODON:00001181
name: food (cooked)
def: "Food material which is cooked." []
synonym: "cooked" EXACT []
is_a: FOODON:00002645 ! food material by process
intersection_of: FOODON:00002645 ! food material by process
intersection_of: RO:0002353 FOODON:03450002 ! output of food cooking
relationship: RO:0002353 FOODON:03450002 ! output of food cooking

[Term]
id: FOODON:00001183
name: bread food product
def: "A staple food prepared from a dough of flour (usually wheat) and water, usually by baking" []
is_a: FOODON:00002456 ! food (baked)
relationship: RO:0002350 FOODON:03400178 ! member of bread (us cfr)

[Term]
id: FOODON:00001184
name: algae material
def: "Material which derives from algae (including single-celled microalgae and  multicellular macroalgae)." []
xref: https://bioregistry.io/reference/siren\:F10419
is_a: FOODON:03420116 ! organism material
intersection_of: FOODON:03420116 ! organism material
intersection_of: RO:0001000 FOODON:03411301 ! derives from algae
relationship: RO:0001000 FOODON:03411301 ! derives from algae

[Term]
id: FOODON:00001185
name: rice food product
is_a: FOODON:00001093 ! cereal grain food product
intersection_of: FOODON:00001093 ! cereal grain food product
intersection_of: RO:0001000 FOODON:03411322 ! derives from rice plant
relationship: RO:0001000 FOODON:03411322 ! derives from rice plant
relationship: RO:0002350 FOODON:03400125 ! member of grain or starch product (us cfr)

[Term]
id: FOODON:00001189
name: oat food product
def: "A food product made from oats." []
synonym: "common oat food product" EXACT []
is_a: FOODON:00001093 ! cereal grain food product
intersection_of: FOODON:00001093 ! cereal grain food product
intersection_of: RO:0001000 NCBITaxon:4498 ! derives from Avena sativa
relationship: RO:0001000 NCBITaxon:4498 ! derives from Avena sativa
relationship: RO:0002350 FOODON:03400125 ! member of grain or starch product (us cfr)

[Term]
id: FOODON:00001191
name: barley food product
is_a: FOODON:00001093 ! cereal grain food product
intersection_of: FOODON:00001093 ! cereal grain food product
intersection_of: RO:0001000 FOODON:03411230 ! derives from barley plant
relationship: RO:0001000 FOODON:03411230 ! derives from barley plant

[Term]
id: FOODON:00001194
name: dry pea food product
def: "A product of the dry seeds of plants of the genus Pisum." []
is_a: FOODON:00001209 ! pulse food product
is_a: FOODON:00001635 ! bean food product
is_a: FOODON:00002813 ! pea food product
intersection_of: FOODON:00001635 ! bean food product
intersection_of: RO:0001000 FOODON:03411338 ! derives from pea plant

[Term]
id: FOODON:00001198
name: broad bean (dried)
def: "A product of the dry seeds of plants of the genus Vicia." []
synonym: "dried fava bean" EXACT []
is_a: FOODON:00001203 ! vetch seed (dried)
is_a: FOODON:00002752 ! bean (dried)
is_a: FOODON:03301227 ! broad bean
intersection_of: FOODON:00002752 ! bean (dried)
intersection_of: FOODON:03301227 ! broad bean

[Term]
id: FOODON:00001201
name: dry bean food product
def: "A dry bean food product refers to a bean product made from a Phaseolus species plant whose seeds are harvested at complete maturity." []
comment: FAO notes: "Only species of Phaseolus should be included, though several countries also include certain types of beans. Commonly classified as Vigna (angularis, mungo, radiata, aconitifolia). In the past, these species were also classified as Phaseolus."
is_a: FOODON:00001209 ! pulse food product
is_a: FOODON:00001757 ! common bean food product

[Term]
id: FOODON:00001203
name: vetch seed (dried)
def: "A product of the  dry seeds of Vicia sativa." []
is_a: FOODON:00001209 ! pulse food product
is_a: FOODON:00002791 ! vetch seed
is_a: FOODON:03307539 ! food (dried)
intersection_of: FOODON:00002791 ! vetch seed
intersection_of: FOODON:03307539 ! food (dried)

[Term]
id: FOODON:00001209
name: pulse food product
def: "PULSES are annual leguminous crops yielding from one to 12 grains or seeds of variable size, shape and colour within a pod. They are used for both food and feed. The term \"pulses\" is limited to crops harvested solely for dry grain, thereby excludingcrops harvested green for food (green peas, green beans, etc.) which are classified as vegetable crops. Also excluded are those crops used mainly for oil extraction (e.g.soybeand and groundnuts) and leguminous crops (e.g. seeds of clover and alfalfa) that are used exclusively for sowing purposes." []
synonym: "pulse" EXACT []
synonym: "pulses" EXACT []
is_a: FOODON:00001264 ! legume food product

[Term]
id: FOODON:00001210
name: wheat flour food product
is_a: FOODON:00001056 ! flour food product
is_a: FOODON:00001141 ! wheat food product

[Term]
id: FOODON:00001211
name: pasta food product
def: "A food made from an unleavened dough of wheat or buckwheat  flour and water, sometimes with other ingredients such as eggs and vegetable  extracts." []
is_a: FOODON:03311737 ! processed food

[Term]
id: FOODON:00001214
name: candy food product
def: "A confection made from a concentrated solution of sugar in water, to which flavorings and colorants are added." []
is_a: FOODON:00001149 ! confectionery food
relationship: FOODON:00002420 FOODON:03420108 ! has ingredient sugar
relationship: RO:0002350 FOODON:03400204 ! member of candy (us cfr)

[Term]
id: FOODON:00001215
name: cacao food product
def: "A food product derived from Theobroma cacao." []
synonym: "cocoa and cocoa products" EXACT []
is_a: FOODON:00001173 ! plant seed food product
intersection_of: FOODON:00001173 ! plant seed food product
intersection_of: RO:0001000 FOODON:03411318 ! derives from cacao plant
relationship: RO:0001000 FOODON:03411318 ! derives from cacao plant
relationship: RO:0002350 FOODON:03400272 ! member of cacao or chocolate product (us cfr)

[Term]
id: FOODON:00001216
name: cream food product
def: "A dairy product that is composed of the higher-butterfat  layer skimmed from the top of milk before homogenization." [http://en.wikipedia.org/wiki/Cream]
xref: langual:thesaurus.asp?termid=C0195
is_a: FOODON:00001257 ! milk or milk based food product

[Term]
id: FOODON:00001218
name: bee food product
def: "A food product with bees or bee substances as a defining ingredient." []
is_a: FOODON:00001177 ! insect food product

[Term]
id: FOODON:00001224
name: meat sausage (cooked)
def: "A sausage made with fresh meats, and then fully cooked." []
xref: https://bioregistry.io/reference/siren\:F10754
is_a: FOODON:00001181 ! food (cooked)
is_a: FOODON:03315904 ! meat sausage
intersection_of: FOODON:03315904 ! meat sausage
intersection_of: RO:0002353 FOODON:03450002 ! output of food cooking

[Term]
id: FOODON:00001226
name: fruit preserve or jam food product
def: "A fruit product that has been prepared and canned or bottled for long term storage. The preparation of fruit preserves traditionally involves the use of pectin as a gelling agent, although sugar or honey may be used as well." [http://en.wikipedia.org/wiki/Fruit_preserves]
is_a: FOODON:00001057 ! plant fruit food product
relationship: RO:0002350 FOODON:03400251 ! member of fruit preserve or jam (us cfr)

[Term]
id: FOODON:00001227
name: jam food product
def: "A product made with whole fruit, cut into pieces or crushed. The fruit is heated with water and sugar to activate the pectin in the fruit. The mixture is then put into containers." [http://en.wikipedia.org/wiki/Fruit_preserves#Jam]
is_a: FOODON:00001226 ! fruit preserve or jam food product

[Term]
id: FOODON:00001231
name: creamy salad dressing
def: "A salad dressing that is usually mayonnaise-based, but which may also contain yogurt, sour cream, or creme fraiche." [http://en.wikipedia.org/wiki/Salad_dressing#Dressings]
is_a: FOODON:00001290 ! salad dressing

[Term]
id: FOODON:00001234
name: mayonnaise food product
def: "A food product made with mayonnaise as a defining ingredient." []
is_a: FOODON:00001231 ! creamy salad dressing
relationship: FOODON:00001301 FOODON:03306409 ! has food substance analog mayonnaise analog

[Term]
id: FOODON:00001241
name: processed pork meat food product
is_a: FOODON:00001010 ! processed meat food product
is_a: FOODON:00001038 ! pork meat food product
intersection_of: FOODON:00001010 ! processed meat food product
intersection_of: FOODON:00001038 ! pork meat food product

[Term]
id: FOODON:00001242
name: spice or herb
def: "A food product that has some spice or herb as a defining ingredient." []
synonym: "herb or spice" EXACT []
xref: langual:thesaurus.asp?termid=H0151
is_a: FOODON:00001015 ! plant food product
union_of: FOODON:00003042 ! herb food product
union_of: FOODON:03303380 ! spice food product
relationship: RO:0002350 FOODON:03400113 ! member of spice or herb (us cfr)

[Term]
id: FOODON:00001243
name: animal lipid food product
is_a: FOODON:00002664 ! lipid food product
is_a: FOODON:00004242 ! animal food product

[Term]
id: FOODON:00001244
name: coffee beverage
def: "A brewed drink prepared from roasted seeds, commonly called coffee beans, of the coffee plant." []
is_a: FOODON:00001139 ! coffee based beverage product

[Term]
id: FOODON:00001245
name: tea beverage (liquid)
def: "A beverage prepared from the cured leaves of Camellia sinensis by combination with hot or boiling water." []
is_a: FOODON:00001138 ! tea based beverage product

[Term]
id: FOODON:00001248
name: fish food product
def: "A fish food product includes products made from any fish species (aquatic vertebrate with gills and fins)." []
is_a: FOODON:00001092 ! vertebrate food product
intersection_of: FOODON:00001092 ! vertebrate food product
intersection_of: RO:0001000 FOODON:03411222 ! derives from fish species
relationship: RO:0001000 FOODON:03411222 ! derives from fish species
relationship: RO:0002350 FOODON:03400267 ! member of seafood or seafood product (us cfr)

[Term]
id: FOODON:00001251
name: avian food product
def: "A food product that is derived from some avian animal." []
is_a: FOODON:00001092 ! vertebrate food product
is_a: FOODON:02020050 ! avian material

[Term]
id: FOODON:00001253
name: plant derived beverage
def: "A beverage derived from plants." []
is_a: FOODON:00001015 ! plant food product
is_a: FOODON:03301977 ! beverage food product

[Term]
id: FOODON:00001254
name: plant derived fermented beverage
is_a: FOODON:00001094 ! fermented beverage
is_a: FOODON:00001253 ! plant derived beverage
intersection_of: FOODON:00001094 ! fermented beverage
intersection_of: FOODON:00001253 ! plant derived beverage

[Term]
id: FOODON:00001255
name: nonfermented plant derived beverage product
is_a: FOODON:00001253 ! plant derived beverage

[Term]
id: FOODON:00001256
name: dairy food product
def: "A dairy food product has mammilian milk or a milk component as an ingredient." []
synonym: "dairy product" EXACT []
synonym: "milk product" EXACT []
xref: langual:thesaurus.asp?termid=H0242
is_a: FOODON:00001092 ! vertebrate food product
is_a: FOODON:00005501 ! mammal material
relationship: RO:0001000 UBERON:0001913 ! derives from milk
relationship: RO:0002350 FOODON:03400148 ! member of milk or milk product (us cfr)

[Term]
id: FOODON:00001257
name: milk or milk based food product
is_a: FOODON:00001256 ! dairy food product

[Term]
id: FOODON:00001258
name: food (fermented)
def: "Food material which has been fermented." []
is_a: FOODON:00002501 ! multi-component food
is_a: FOODON:00002645 ! food material by process
relationship: RO:0002353 FOODON:00001304 ! output of food fermentation

[Term]
id: FOODON:00001261
name: vegetable food product
def: "A plant food product which derives from one or more vegetables." []
comment: FAO definition for vegetable: "Vegetables are plants cultivated both as field crops and garden crops, both in the open and under glass." and also: "Vegetables are grouped according to botanic characteristics as follows: leafy or stem vegetables (e.g., cabbage); fruit-bearing vegetables (e.g., melons); flower vegetables (e.g., cauliflowers); root, bulb and tuberous vegetables (e.g., onion); leguminous vegetables (e.g., green peas); other vegetables (e.g., green maize and mushrooms)."
is_a: FOODON:00001015 ! plant food product
relationship: RO:0001000 FOODON:03411579 ! derives from vegetable-producing plant
relationship: RO:0002350 FOODON:03400152 ! member of vegetable or vegetable product (us cfr)

[Term]
id: FOODON:00001262
name: botanical fruit food product
def: "Mature ovary of a plant, with a fleshy part of the carpel that develops with the seed to attract animals for aid in dispersal. Botanically, nuts are considered fruits." [http://eurovoc.europa.eu/drupal/?q=request&amp;uri=http\://eurovoc.europa.eu/1115, http://oek1.fao.org/skosmos/agrovoc/en/page/c_3119, http://www.fao.org/pollination/resources/glossary/en/, https://en.wikipedia.org/wiki/Fruit]
is_a: FOODON:00001015 ! plant food product

[Term]
id: FOODON:00001264
name: legume food product
def: "A one-celled fruit (pod) usually dehiscing down both sutures, and having the seed attached along a ventral suture. (Roubik 1995)" []
synonym: "legume" EXACT []
is_a: FOODON:00001262 ! botanical fruit food product

[Term]
id: FOODON:00001278
name: cake food product
def: "A food that is usually sweet and often baked. Cakes normally combine some kind of flour, a sweetening agent (commonly sugar), a binding agent (generally egg, though gluten  or starch  are often used by lacto-vegetarians and vegans), fats (usually butter, shortening, or margarine, although a fruit puree such as applesauce is sometimes substituted to avoid using fat), a liquid (milk, water or fruit juice), flavors and some form of leavening agent (such as yeast or baking powder), though many cakes lack these ingredients and instead rely on air bubbles in the dough to expand and cause the cake to rise. Cake is often frosted with buttercream  or marzipan, and finished with piped borders and crystallized fruit." [Wikipedia:Cake]
is_a: FOODON:00001626 ! bakery food product

[Term]
id: FOODON:00001282
name: beef (ground)
def: "Beef that has been ground." []
comment: A ground beef product is made of beef that has been finely chopped with a knife or a meat grinder (American English) or mincing machine (British English). Ground beef is used in many recipes including hamburgers and spaghetti Bolognese.
synonym: "beef mince" EXACT []
synonym: "ground beef" EXACT []
synonym: "hamburger meat" EXACT []
synonym: "minced beef" EXACT []
is_a: FOODON:00001041 ! cow food product
is_a: FOODON:02000412 ! piece(s) of beef

[Term]
id: FOODON:00001283
name: poultry food product
def: "A food product that is derived from some poultry." []
is_a: FOODON:00001251 ! avian food product
is_a: FOODON:02020686 ! poultry material
relationship: RO:0001000 FOODON:03411563 ! derives from poultry or game bird
relationship: RO:0002350 FOODON:03400273 ! member of poultry or poultry product (us cfr)

[Term]
id: FOODON:00001286
name: turkey meat food product
def: "A turkey meat food product is any food product made predominantly of turkey parts." []
is_a: FOODON:00001131 ! poultry meat food product
intersection_of: FOODON:00001131 ! poultry meat food product
intersection_of: RO:0001000 FOODON:03411236 ! derives from turkey (bird)
relationship: RO:0001000 FOODON:03411236 ! derives from turkey (bird)

[Term]
id: FOODON:00001288
name: cantaloupe fruit food product
def: "Cantaloupe (also known as muskmelon (India and the United States), mushmelon, rockmelon (in Australian states and in New Zealand), sweet melon, spanspek (South Africa), or capuchin (Scotland) refers to a variety of the Cucumis melo species in the Cucurbitaceae family." []
synonym: "cantaloup" EXACT []
synonym: "muskmelon" EXACT []
is_a: FOODON:00001153 ! muskmelon (Cucumis melo) fruit food product

[Term]
id: FOODON:00001290
name: salad dressing
def: "A sauce for a salad." []
is_a: FOODON:00001133 ! condiment
is_a: FOODON:00002146 ! plant material dressing
relationship: RO:0002350 FOODON:03400292 ! member of standardized dressing (us cfr)

[Term]
id: FOODON:00001293
name: shellfish food product
is_a: FOODON:00001046 ! animal seafood product
is_a: FOODON:00001176 ! invertebrate food product
intersection_of: FOODON:00001046 ! animal seafood product
intersection_of: FOODON:00001176 ! invertebrate food product
intersection_of: RO:0001000 FOODON:03411433 ! derives from shellfish species
relationship: RO:0001000 FOODON:03411433 ! derives from shellfish species

[Term]
id: FOODON:00001304
name: food fermentation
def: "A fermentation process in which either carbohydrates, proteins or fats are modified through microbial, enzymatic and/or other biological process." []
xref: langual:thesaurus.asp?termid=J0104
is_a: FOODON:03460119 ! microbial/enzymatic modification process
is_a: FOODON:03470107 ! food preservation process

[Term]
id: FOODON:00001305
name: hoi-dong
def: "Hoi-dong is fermented sea mussel" []
is_a: FOODON:00001054 ! fermented fish or seafood food product
is_a: FOODON:00002051 ! mussel food product
intersection_of: FOODON:00001054 ! fermented fish or seafood food product
intersection_of: RO:0001000 FOODON:03411223 ! derives from mussel

[Term]
id: FOODON:00001314
name: fermented meat product
def: "Fermented meat product is any product made primarily of meat subjected to a fermentation process." []
is_a: FOODON:00001258 ! food (fermented)
intersection_of: FOODON:00001258 ! food (fermented)
intersection_of: RO:0001000 FOODON:00001006 ! derives from mammalian meat food product
relationship: RO:0001000 FOODON:00001006 ! derives from mammalian meat food product

[Term]
id: FOODON:00001330
name: tuaw jaew
def: "Tuaw jaew is a kind of fermented vegetable." []
is_a: FOODON:00001078 ! fermented soybean food product
intersection_of: FOODON:00001078 ! fermented soybean food product
intersection_of: RO:0001000 FOODON:00002265 ! derives from soybean seed (field) food product
relationship: RO:0001000 FOODON:00002265 ! derives from soybean seed (field) food product

[Term]
id: FOODON:00001564
name: blood meal
def: "Blood meal is a dry, inert powder made from blood used as a high-nitrogen organic fertilizer and a high protein animal feed." []
comment: It is one of the highest non-synthetic sources of nitrogen. It usually comes from cattle or hogs as a slaughterhouse by-product. N = 13.25%, P = 1.0%, K = 0.6%.\n\nSIREN DB annotation:\n* medium ground FOODON:03430117\n* blood UBERON:0000178\n* water removal process FOODON:03460138\n* preservation by dehydration or drying FOODON:03470116\n* animal as consumer FOODON:03510021
xref: https://bioregistry.io/reference/siren\:F10831
is_a: FOODON:00001594 ! animal based food product for animal
is_a: FOODON:03302001 ! animal-derived food
relationship: RO:0000086 FOODON:03430106 ! has quality finely ground

[Term]
id: FOODON:00001578
name: albacore food product
def: "A food product which has albacore tuna as a defining ingredient." []
is_a: FOODON:00001248 ! fish food product
is_a: FOODON:02022610 ! albacore material
intersection_of: FOODON:00001248 ! fish food product
intersection_of: RO:0001000 NCBITaxon:8235 ! derives from Thunnus alalunga
relationship: RO:0001000 NCBITaxon:8235 ! derives from Thunnus alalunga

[Term]
id: FOODON:00001579
name: alcoholic beverage
def: "An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar." []
xref: https://bioregistry.io/reference/siren\:F10770
is_a: FOODON:00001094 ! fermented beverage

[Term]
id: FOODON:00001587
name: almond food product
xref: https://bioregistry.io/reference/siren\:F9864
is_a: FOODON:00001172 ! nut food product
intersection_of: FOODON:00001172 ! nut food product
intersection_of: RO:0001000 FOODON:00003523 ! derives from almond
relationship: RO:0001000 FOODON:00003523 ! derives from almond

[Term]
id: FOODON:00001594
name: animal based food product for animal
is_a: FOODON:03309997 ! food material for animals
intersection_of: FOODON:03309997 ! food material for animals
intersection_of: RO:0001000 FOODON:03420127 ! derives from animal (whole or piece(s))
relationship: RO:0001000 FOODON:03420127 ! derives from animal (whole or piece(s))

[Term]
id: FOODON:00001595
name: animal based refined or partially-refined food product
is_a: FOODON:00002196 ! refined or partially-refined food product
is_a: FOODON:00004242 ! animal food product

[Term]
id: FOODON:00001599
name: animal fat or oil refined food product
is_a: FOODON:00001243 ! animal lipid food product
is_a: FOODON:00001595 ! animal based refined or partially-refined food product
is_a: FOODON:03420190 ! fat or oil

[Term]
id: FOODON:00001604
name: animal product sandwich
def: "A sandwich which has at least one prominent meat ingredient." []
is_a: FOODON:03301906 ! sandwich
relationship: FOODON:00001563 FOODON:00002671 ! has defining ingredient animal meat food product

[Term]
id: FOODON:00001605
name: animal product sausage
def: "Sausage which has animal meat as a defining ingredient." []
is_a: FOODON:00001007 ! meat sausage food product

[Term]
id: FOODON:00001610
name: apple condiment
is_a: FOODON:00001133 ! condiment
intersection_of: FOODON:00001133 ! condiment
intersection_of: RO:0001000 FOODON:03310788 ! derives from apple (whole or pieces)
relationship: RO:0001000 FOODON:03310788 ! derives from apple (whole or pieces)

[Term]
id: FOODON:00001611
name: apple food product
is_a: FOODON:00001158 ! pomaceous fruit food product
intersection_of: FOODON:00001158 ! pomaceous fruit food product
intersection_of: RO:0001000 FOODON:00002473 ! derives from apple
relationship: RO:0001000 FOODON:00002473 ! derives from apple

[Term]
id: FOODON:00001612
name: apple preserve or jam food product
is_a: FOODON:00001226 ! fruit preserve or jam food product
is_a: FOODON:00001611 ! apple food product
intersection_of: FOODON:00001226 ! fruit preserve or jam food product
intersection_of: FOODON:00001611 ! apple food product

[Term]
id: FOODON:00001615
name: apricot food product
def: "A food product deriving from one or more apricots." []
is_a: FOODON:00002277 ! stone fruit food product
relationship: RO:0001000 FOODON:00003476 ! derives from apricot

[Term]
id: FOODON:00001616
name: apricot preserve or jam food product
is_a: FOODON:00001226 ! fruit preserve or jam food product
is_a: FOODON:00001615 ! apricot food product
intersection_of: FOODON:00001226 ! fruit preserve or jam food product
intersection_of: FOODON:00001615 ! apricot food product

[Term]
id: FOODON:00001625
name: avocado food product
def: "A food product deriving from one or more avocados." []
is_a: FOODON:00002141 ! plant fruit as vegetable food product
is_a: FOODON:00002277 ! stone fruit food product
relationship: RO:0001000 FOODON:00003600 ! derives from avocado

[Term]
id: FOODON:00001626
name: bakery food product
def: "Food material which is output of or is part of a home or commercial bakery process." []
is_a: FOODON:00002645 ! food material by process
relationship: RO:0002350 FOODON:03400191 ! member of bakery product (us cfr)

[Term]
id: FOODON:00001628
name: banana food product
def: "A plant fruit food product derived from a banana tree (genus Musa)." []
is_a: FOODON:00001057 ! plant fruit food product
relationship: RO:0001000 NCBITaxon:4640 ! derives from Musa

[Term]
id: FOODON:00001633
name: barley vegetable food product
is_a: FOODON:00001261 ! vegetable food product
intersection_of: FOODON:00001261 ! vegetable food product
intersection_of: RO:0001000 FOODON:03411230 ! derives from barley plant
relationship: RO:0001000 FOODON:03411230 ! derives from barley plant

[Term]
id: FOODON:00001635
name: bean food product
def: "A bean vegetable food product is a human or animal food product - such as a snap, shell or dry bean product - derived from the fruit pod, seed, or leaf of one of several genera of the flowering plant family Fabaceae." []
is_a: FOODON:00001264 ! legume food product
is_a: FOODON:00002153 ! plant seed vegetable food product

[Term]
id: FOODON:00001638
name: beet food product
is_a: FOODON:00002150 ! plant root vegetable food product
intersection_of: FOODON:00002150 ! plant root vegetable food product
intersection_of: RO:0001000 FOODON:03411309 ! derives from beet plant
relationship: RO:0001000 FOODON:03411309 ! derives from beet plant

[Term]
id: FOODON:00001640
name: berry food product
is_a: FOODON:00001057 ! plant fruit food product
intersection_of: FOODON:00001057 ! plant fruit food product
intersection_of: RO:0001000 FOODON:03411231 ! derives from berry plant
relationship: RO:0001000 FOODON:03411231 ! derives from berry plant

[Term]
id: FOODON:00001656
name: blueberry food product
is_a: FOODON:00001640 ! berry food product
intersection_of: FOODON:00001640 ! berry food product
intersection_of: RO:0001000 FOODON:03411491 ! derives from blueberry plant
relationship: RO:0001000 FOODON:03411491 ! derives from blueberry plant

[Term]
id: FOODON:00001657
name: blueberry preserve or jam food product
is_a: FOODON:00001226 ! fruit preserve or jam food product
is_a: FOODON:00001656 ! blueberry food product
intersection_of: FOODON:00001226 ! fruit preserve or jam food product
intersection_of: FOODON:00001656 ! blueberry food product

[Term]
id: FOODON:00001659
name: bluefish food product
is_a: FOODON:00001248 ! fish food product

[Term]
id: FOODON:00001665
name: broad bean food product
def: "A broad bean food product is a product derived from the broad bean plant." []
is_a: FOODON:00001635 ! bean food product
intersection_of: FOODON:00001635 ! bean food product
intersection_of: RO:0001000 FOODON:03411367 ! derives from broad bean plant
relationship: RO:0001000 FOODON:03411367 ! derives from broad bean plant

[Term]
id: FOODON:00001666
name: broccoli food product
is_a: FOODON:00002142 ! plant head vegetable food product
is_a: FOODON:00002156 ! plant stem or spear food product
is_a: FOODON:00003341 ! brassica food product
intersection_of: FOODON:00002142 ! plant head vegetable food product
intersection_of: FOODON:00002156 ! plant stem or spear food product
intersection_of: RO:0001000 FOODON:03411443 ! derives from broccoli plant
relationship: RO:0001000 FOODON:03411443 ! derives from broccoli plant

[Term]
id: FOODON:00001670
name: brussels sprout food product
is_a: FOODON:00002142 ! plant head vegetable food product
is_a: FOODON:00003341 ! brassica food product
intersection_of: FOODON:00002142 ! plant head vegetable food product
intersection_of: RO:0001000 FOODON:03411611 ! derives from brussels sprout plant
relationship: RO:0001000 FOODON:03411611 ! derives from brussels sprout plant

[Term]
id: FOODON:00001673
name: butter product analog
is_a: FOODON:00001801 ! dairy product analog

[Term]
id: FOODON:00001675
name: cabbage juice food product
is_a: FOODON:00001016 ! cabbage food product
is_a: FOODON:03301444 ! vegetable juice food product
intersection_of: FOODON:00001016 ! cabbage food product
intersection_of: FOODON:03301444 ! vegetable juice food product

[Term]
id: FOODON:00001677
name: cabbage head food product
def: "A cabbage vegetable food product is a food product derived from the head or leaf portion of a cabbage plant." []
is_a: FOODON:00001016 ! cabbage food product
is_a: FOODON:00002142 ! plant head vegetable food product

[Term]
id: FOODON:00001686
name: carrot juice food product
is_a: FOODON:00001687 ! carrot food product
is_a: FOODON:03301444 ! vegetable juice food product
intersection_of: FOODON:00001687 ! carrot food product
intersection_of: FOODON:03301444 ! vegetable juice food product

[Term]
id: FOODON:00001687
name: carrot food product
is_a: FOODON:00002150 ! plant root vegetable food product

[Term]
id: FOODON:00001688
name: cashew nut food product
is_a: FOODON:00001172 ! nut food product
intersection_of: FOODON:00001172 ! nut food product
intersection_of: RO:0001000 FOODON:03301357 ! derives from cashew nut (raw)
relationship: RO:0001000 FOODON:03301357 ! derives from cashew nut (raw)

[Term]
id: FOODON:00001696
name: cattle cured meat food product
is_a: FOODON:00001039 ! cured meat food product
is_a: FOODON:00001041 ! cow food product
intersection_of: FOODON:00001039 ! cured meat food product
intersection_of: FOODON:00001041 ! cow food product

[Term]
id: FOODON:00001699
name: cattle sandwich
is_a: FOODON:00001604 ! animal product sandwich
relationship: RO:0001000 NCBITaxon:9913 ! derives from Bos taurus

[Term]
id: FOODON:00001700
name: cattle sausage food product
is_a: FOODON:03310675 ! luncheon meat
intersection_of: FOODON:00001605 ! animal product sausage
intersection_of: RO:0001000 NCBITaxon:9913 ! derives from Bos taurus
relationship: RO:0001000 NCBITaxon:9913 ! derives from Bos taurus

[Term]
id: FOODON:00001703
name: cauliflower food product
def: "A food product that derives from a cauliflower plant." []
is_a: FOODON:00002140 ! plant floret vegetable food product
is_a: FOODON:00003341 ! brassica food product
intersection_of: FOODON:00003341 ! brassica food product
intersection_of: RO:0001000 NCBITaxon:3715 ! derives from Brassica oleracea var. botrytis
relationship: RO:0001000 NCBITaxon:3715 ! derives from Brassica oleracea var. botrytis

[Term]
id: FOODON:00001704
name: celery food product
def: "A plant food product derived from a celery plant (Apium graveolens)" []
is_a: FOODON:00002156 ! plant stem or spear food product
intersection_of: FOODON:00001015 ! plant food product
intersection_of: RO:0001000 NCBITaxon:4045 ! derives from Apium graveolens
relationship: RO:0001000 NCBITaxon:4045 ! derives from Apium graveolens

[Term]
id: FOODON:00001709
name: cereal food product
def: "A cereal is any grass cultivated for the edible components of its grain composed of the endosperm, germ, and bran" []
synonym: "cereal product" EXACT []
xref: https://bioregistry.io/reference/siren\:F11705
is_a: FOODON:00001093 ! cereal grain food product

[Term]
id: FOODON:00001712
name: cheese product analog
is_a: FOODON:00001801 ! dairy product analog
intersection_of: FOODON:00001801 ! dairy product analog
intersection_of: FOODON:00001301 FOODON:00001013 ! has food substance analog cheese food product
relationship: FOODON:00001301 FOODON:00001013 ! has food substance analog cheese food product

[Term]
id: FOODON:00001714
name: food material component
def: "Food material which normally exists as an ingredient to another food material, rather than eaten on its own.  This includes chemical food components." []
comment: On Feb 25th 2025 the definition was loosened to include the subclass "chemical food component".
is_a: FOODON:00002403 ! food material

[Term]
id: FOODON:00001733
name: chocolate candy food product
is_a: FOODON:00001214 ! candy food product

[Term]
id: FOODON:00001742
name: citrus preserve or jam food product
is_a: FOODON:00001151 ! citrus fruit food product
is_a: FOODON:00001226 ! fruit preserve or jam food product
intersection_of: FOODON:00001151 ! citrus fruit food product
intersection_of: FOODON:00001226 ! fruit preserve or jam food product
relationship: RO:0001000 FOODON:03411139 ! derives from citrus family

[Term]
id: FOODON:00001748
name: coconut beverage
is_a: FOODON:00001253 ! plant derived beverage
is_a: FOODON:03316908 ! coconut food product
intersection_of: FOODON:00001253 ! plant derived beverage
intersection_of: FOODON:03316908 ! coconut food product

[Term]
id: FOODON:00001750
name: cod food product
is_a: FOODON:00001248 ! fish food product
intersection_of: FOODON:00001248 ! fish food product
intersection_of: RO:0001000 FOODON:03411423 ! derives from cod
relationship: RO:0001000 FOODON:03411423 ! derives from cod

[Term]
id: FOODON:00001755
name: collard food product
is_a: FOODON:00003341 ! brassica food product
intersection_of: FOODON:00003341 ! brassica food product
intersection_of: RO:0001000 FOODON:03411385 ! derives from collard plant
relationship: RO:0001000 FOODON:03411385 ! derives from collard plant

[Term]
id: FOODON:00001757
name: common bean food product
is_a: FOODON:00001635 ! bean food product
intersection_of: FOODON:00001635 ! bean food product
intersection_of: RO:0001000 FOODON:03411999 ! derives from common bean plant
relationship: RO:0001000 FOODON:03411999 ! derives from common bean plant

[Term]
id: FOODON:00001759
name: common oat cereal food product
is_a: FOODON:00001189 ! oat food product
is_a: FOODON:00001709 ! cereal food product
intersection_of: FOODON:00001709 ! cereal food product
intersection_of: RO:0001000 NCBITaxon:4498 ! derives from Avena sativa

[Term]
id: FOODON:00001762
name: cookie food product
is_a: FOODON:00001626 ! bakery food product

[Term]
id: FOODON:00001765
name: vegetable corn food product
is_a: FOODON:00001093 ! cereal grain food product
is_a: FOODON:00001142 ! maize (corn) food product
is_a: FOODON:00002153 ! plant seed vegetable food product
intersection_of: FOODON:00001261 ! vegetable food product
intersection_of: RO:0001000 NCBITaxon:381124 ! derives from Zea mays subsp. mays
relationship: RO:0001000 NCBITaxon:381124 ! derives from Zea mays subsp. mays

[Term]
id: FOODON:00001771
name: cow milk based food product
is_a: FOODON:00001118 ! cattle dairy food product
is_a: FOODON:00001257 ! milk or milk based food product
intersection_of: FOODON:00001118 ! cattle dairy food product
intersection_of: RO:0001000 FOODON:03307455 ! derives from cow milk (raw)
relationship: RO:0001000 FOODON:03307455 ! derives from cow milk (raw)

[Term]
id: FOODON:00001772
name: cow milk butter food product
is_a: FOODON:00001771 ! cow milk based food product

[Term]
id: FOODON:00001775
name: cow milk cream food product
is_a: FOODON:00001216 ! cream food product
is_a: FOODON:00001771 ! cow milk based food product

[Term]
id: FOODON:00001792
name: crustacean food product
is_a: FOODON:00001293 ! shellfish food product
is_a: FOODON:00005704 ! crustacean material
intersection_of: FOODON:00001293 ! shellfish food product
intersection_of: RO:0001000 FOODON:03411374 ! derives from crustacean
relationship: RO:0001000 FOODON:03411374 ! derives from crustacean

[Term]
id: FOODON:00001800
name: dairy dessert food product
is_a: FOODON:00001256 ! dairy food product
is_a: FOODON:03303220 ! dessert food
relationship: RO:0001000 FOODON:03411201 ! derives from dairy cow

[Term]
id: FOODON:00001801
name: dairy product analog
xref: https://bioregistry.io/reference/siren\:F1442
is_a: FOODON:00001871 ! food material analog

[Term]
id: FOODON:00001809
name: dietary or therapeutic formulation food
comment: Damion Dooley's note: This category was created to organize SIREN inspired food products.  It will probably get merged with the upper level 'dietary supplement' food product type items.
is_a: FOODON:00002147 ! food material by consumer group

[Term]
id: FOODON:00001821
name: doughnut food product
is_a: FOODON:00002347 ! wheat based bakery food product

[Term]
id: FOODON:00001823
name: milled durum wheat
def: "Durum wheat which has been milled." []
is_a: FOODON:00001825 ! durum wheat food product
is_a: FOODON:00004509 ! milled food product

[Term]
id: FOODON:00001825
name: durum wheat food product
def: "A hard wheat food product which has durum wheat as a defining ingredient." []
is_a: FOODON:00001947 ! hard wheat food product
intersection_of: FOODON:00001947 ! hard wheat food product
intersection_of: RO:0001000 NCBITaxon:4567 ! derives from Triticum turgidum subsp. durum
relationship: RO:0001000 NCBITaxon:4567 ! derives from Triticum turgidum subsp. durum

[Term]
id: FOODON:00001830
name: eggplant food product
def: "A food product deriving from one or more eggplants." []
is_a: FOODON:00002141 ! plant fruit as vegetable food product
relationship: RO:0001000 FOODON:00003618 ! derives from eggplant

[Term]
id: FOODON:00001838
name: fermented cereal beverage
is_a: FOODON:00001254 ! plant derived fermented beverage
intersection_of: FOODON:00001254 ! plant derived fermented beverage
intersection_of: RO:0001000 FOODON:03411324 ! derives from grain plant
relationship: RO:0001000 FOODON:03411324 ! derives from grain plant

[Term]
id: FOODON:00001855
name: fish refined food product
is_a: FOODON:00001595 ! animal based refined or partially-refined food product

[Term]
id: FOODON:00001857
name: food flavoring or seasoning
is_a: FOODON:00001714 ! food material component
relationship: RO:0002350 FOODON:03400133 ! member of flavoring or seasoning (us cfr)

[Term]
id: FOODON:00001859
name: flaxseed food product
synonym: "linseed food product" EXACT []
is_a: FOODON:00001173 ! plant seed food product
intersection_of: FOODON:00001173 ! plant seed food product
intersection_of: RO:0001000 NCBITaxon:4006 ! derives from Linum usitatissimum
relationship: RO:0001000 NCBITaxon:4006 ! derives from Linum usitatissimum

[Term]
id: FOODON:00001860
name: flax vegetable food product
is_a: FOODON:00001859 ! flaxseed food product
is_a: FOODON:00002153 ! plant seed vegetable food product
intersection_of: FOODON:00002153 ! plant seed vegetable food product
intersection_of: RO:0001000 NCBITaxon:4006 ! derives from Linum usitatissimum

[Term]
id: FOODON:00001867
name: food dressing
def: "A mix or ready made sauce for dipping or adding to food, especially salad." []
is_a: FOODON:00002501 ! multi-component food

[Term]
id: FOODON:00001868
name: food filling material
is_a: FOODON:00001714 ! food material component

[Term]
id: FOODON:00001871
name: food material analog
is_a: FOODON:00001002 ! food product

[Term]
id: FOODON:00001872
name: food material (to be processed)
def: "This is a working folder that holds LanguaL SIREN database product types that need to be reviewed for placement within the food product hierarchy." []
is_a: FOODON:00002403 ! food material

[Term]
id: FOODON:00001874
name: food supplement
is_a: FOODON:00001809 ! dietary or therapeutic formulation food

[Term]
id: FOODON:00001878
name: frozen dairy dessert
is_a: FOODON:00001800 ! dairy dessert food product
is_a: FOODON:00001879 ! frozen dairy food product
intersection_of: FOODON:00001800 ! dairy dessert food product
intersection_of: FOODON:00001879 ! frozen dairy food product

[Term]
id: FOODON:00001879
name: frozen dairy food product
is_a: FOODON:00001256 ! dairy food product

[Term]
id: FOODON:00001881
name: frozen yogurt food product
is_a: FOODON:00001878 ! frozen dairy dessert

[Term]
id: FOODON:00001882
name: fruit based alcoholic beverage
is_a: FOODON:00001579 ! alcoholic beverage

[Term]
id: FOODON:00001888
name: fruit jelly food product
is_a: FOODON:00001057 ! plant fruit food product

[Term]
id: FOODON:00001905
name: ginseng plant food product
is_a: FOODON:00001015 ! plant food product
intersection_of: FOODON:00001015 ! plant food product
intersection_of: RO:0001000 FOODON:03411673 ! derives from ginseng plant
relationship: RO:0001000 FOODON:03411673 ! derives from ginseng plant

[Term]
id: FOODON:00001916
name: grain based alcoholic beverage
is_a: FOODON:00001882 ! fruit based alcoholic beverage
intersection_of: FOODON:00001579 ! alcoholic beverage
intersection_of: RO:0001000 FOODON:03411324 ! derives from grain plant
relationship: RO:0001000 FOODON:03411324 ! derives from grain plant

[Term]
id: FOODON:00001917
name: grain based bakery food product
is_a: FOODON:00001093 ! cereal grain food product
is_a: FOODON:00002151 ! plant seed based bakery food product
intersection_of: FOODON:00002151 ! plant seed based bakery food product
intersection_of: RO:0001000 FOODON:03411324 ! derives from grain plant

[Term]
id: FOODON:00001922
name: grape based alcoholic beverage
is_a: FOODON:00001882 ! fruit based alcoholic beverage

[Term]
id: FOODON:00001925
name: grape based wine or wine-like food product
is_a: FOODON:00001922 ! grape based alcoholic beverage
is_a: FOODON:00002364 ! wine or wine-like food product
relationship: RO:0001000 FOODON:03301123 ! derives from grape (raw)

[Term]
id: FOODON:00001929
name: grapefruit food product
is_a: FOODON:00001151 ! citrus fruit food product
intersection_of: FOODON:00001151 ! citrus fruit food product
intersection_of: RO:0001000 FOODON:03301702 ! derives from grapefruit (raw)
relationship: RO:0001000 FOODON:03301702 ! derives from grapefruit (raw)

[Term]
id: FOODON:00001931
name: gravy or sauce
is_a: FOODON:00001714 ! food material component
relationship: RO:0002350 FOODON:03400286 ! member of gravy or sauce (us cfr)

[Term]
id: FOODON:00001934
name: green bean food product
is_a: FOODON:00001757 ! common bean food product
intersection_of: FOODON:00001757 ! common bean food product
intersection_of: RO:0001000 FOODON:03411371 ! derives from green bean plant
relationship: RO:0001000 FOODON:03411371 ! derives from green bean plant

[Term]
id: FOODON:00001935
name: green bell pepper food product
is_a: FOODON:00003013 ! bell pepper food product
intersection_of: FOODON:00003013 ! bell pepper food product
intersection_of: RO:0001000 FOODON:03412629 ! derives from green bell pepper plant
relationship: RO:0001000 FOODON:03412629 ! derives from green bell pepper plant

[Term]
id: FOODON:00001941
name: haddock food product
is_a: FOODON:00001248 ! fish food product

[Term]
id: FOODON:00001947
name: hard wheat food product
is_a: FOODON:00001141 ! wheat food product
intersection_of: FOODON:00001141 ! wheat food product
intersection_of: RO:0001000 FOODON:03411418 ! derives from hard wheat plant
relationship: RO:0001000 FOODON:03411418 ! derives from hard wheat plant

[Term]
id: FOODON:00001949
name: hemp food product
def: "A food product that derives from a hemp plant." []
is_a: FOODON:00001093 ! cereal grain food product
intersection_of: FOODON:00001093 ! cereal grain food product
intersection_of: RO:0001000 NCBITaxon:3483 ! derives from Cannabis sativa
relationship: RO:0001000 NCBITaxon:3483 ! derives from Cannabis sativa

[Term]
id: FOODON:00001955
name: hot pepper spice food product
is_a: FOODON:00001956 ! hot pepper food product
is_a: FOODON:03317238 ! spice (capsicum-based)

[Term]
id: FOODON:00001956
name: hot pepper food product
synonym: "red pepper" EXACT []
is_a: FOODON:00002111 ! pepper vegetable food product
intersection_of: FOODON:00002111 ! pepper vegetable food product
intersection_of: RO:0001000 FOODON:03411643 ! derives from hot pepper plant
relationship: RO:0001000 FOODON:03411643 ! derives from hot pepper plant

[Term]
id: FOODON:00001958
name: human milk based food product
is_a: FOODON:00001257 ! milk or milk based food product
intersection_of: FOODON:00001257 ! milk or milk based food product
intersection_of: RO:0001000 FOODON:03303918 ! derives from human milk (raw)
relationship: RO:0001000 FOODON:03303918 ! derives from human milk (raw)

[Term]
id: FOODON:00001981
name: kale food product
def: "A food product made from a kale plant." []
is_a: FOODON:00002143 ! plant leaf food product
is_a: FOODON:00003341 ! brassica food product
intersection_of: FOODON:00002143 ! plant leaf food product
intersection_of: RO:0001000 FOODON:03411281 ! derives from kale plant
relationship: RO:0001000 FOODON:03411281 ! derives from kale plant

[Term]
id: FOODON:00001992
name: lamb meat food product
def: "Lamb meat food product is a meat product taken from a lamb, a sheep less than a year old." []
is_a: FOODON:00002236 ! sheep meat food product

[Term]
id: FOODON:00001997
name: lentil food product
is_a: FOODON:00002153 ! plant seed vegetable food product
intersection_of: FOODON:00002153 ! plant seed vegetable food product
intersection_of: RO:0001000 FOODON:03411268 ! derives from lentil plant
relationship: RO:0001000 FOODON:03411268 ! derives from lentil plant

[Term]
id: FOODON:00002000
name: lima bean food product
def: "A lima bean vegetable food product is any food product derived primarily from lima beans." []
is_a: FOODON:00001635 ! bean food product
intersection_of: FOODON:00001635 ! bean food product
intersection_of: RO:0001000 FOODON:03411397 ! derives from lima bean plant
relationship: RO:0001000 FOODON:03411397 ! derives from lima bean plant

[Term]
id: FOODON:00002007
name: lobster food product
def: "A food product that is derived from some lobster." []
is_a: FOODON:00001792 ! crustacean food product
is_a: FOODON:02021453 ! lobster material
intersection_of: FOODON:00001792 ! crustacean food product
intersection_of: RO:0001000 FOODON:03411505 ! derives from lobster
relationship: RO:0001000 FOODON:03411505 ! derives from lobster

[Term]
id: FOODON:00002022
name: margarine food product
def: "A food product made from margarine." []
is_a: FOODON:00001673 ! butter product analog
relationship: RO:0001000 FOODON:03411017 ! derives from oil-producing plant

[Term]
id: FOODON:00002027
name: meat product analog
is_a: FOODON:00001871 ! food material analog
relationship: RO:0002350 FOODON:03400132 ! member of meat product analog (us cfr)

[Term]
id: FOODON:00002029
name: melon food product
is_a: FOODON:00001150 ! cucurbit fruit food product
intersection_of: FOODON:00001150 ! cucurbit fruit food product
intersection_of: RO:0001000 FOODON:03411283 ! derives from melon plant
relationship: RO:0001000 FOODON:03411283 ! derives from melon plant

[Term]
id: FOODON:00002031
name: milk based gravy or sauce food product
is_a: FOODON:00001931 ! gravy or sauce
intersection_of: FOODON:00001931 ! gravy or sauce
intersection_of: FOODON:00002420 FOODON:03307455 ! has ingredient cow milk (raw)
relationship: FOODON:00002420 FOODON:03307455 ! has ingredient cow milk (raw)

[Term]
id: FOODON:00002032
name: milk based product analog
is_a: FOODON:00001801 ! dairy product analog

[Term]
id: FOODON:00002034
name: milk beverage analog
is_a: FOODON:00002032 ! milk based product analog
relationship: RO:0002350 FOODON:03400182 ! member of milk analog (us cfr)

[Term]
id: FOODON:00002041
name: mineral water food product
def: "Mineral water is water from a mineral spring that contains various minerals, such as salts and sulfur compounds. Mineral water may be classified as \"still\" or \"sparkling\" (carbonated/effervescent) according to the presence or absence of added gases." []
synonym: "mineral water" EXACT []
is_a: FOODON:00002340 ! water food product
relationship: RO:0001000 FOODON:03411288 ! derives from mineral water (food source)

[Term]
id: FOODON:00002044
name: mollusc food product
synonym: "mollusk food product" EXACT []
is_a: FOODON:00001293 ! shellfish food product
intersection_of: FOODON:00001293 ! shellfish food product
intersection_of: RO:0001000 FOODON:03412112 ! derives from mollusc
relationship: RO:0001000 FOODON:03412112 ! derives from mollusc

[Term]
id: FOODON:00002051
name: mussel food product
def: "A food product that is derived from some mussel." []
is_a: FOODON:00002044 ! mollusc food product
is_a: FOODON:02020797 ! mussel material
intersection_of: FOODON:00002044 ! mollusc food product
intersection_of: RO:0001000 FOODON:03411223 ! derives from mussel
relationship: RO:0001000 FOODON:03411223 ! derives from mussel

[Term]
id: FOODON:00002053
name: mustard food product
is_a: FOODON:00003341 ! brassica food product
intersection_of: FOODON:00003341 ! brassica food product
intersection_of: RO:0001000 FOODON:03412069 ! derives from mustard plant
relationship: RO:0001000 FOODON:03412069 ! derives from mustard plant

[Term]
id: FOODON:00002057
name: nonalcoholic beverage
is_a: FOODON:03301977 ! beverage food product

[Term]
id: FOODON:00002065
name: olive fat or oil refined food product
is_a: FOODON:00002139 ! plant fat or oil refined food product
relationship: RO:0001000 NCBITaxon:4146 ! derives from Olea europaea

[Term]
id: FOODON:00002069
name: onion food product
is_a: FOODON:00002150 ! plant root vegetable food product
intersection_of: FOODON:00002150 ! plant root vegetable food product
intersection_of: RO:0001000 FOODON:03411300 ! derives from onion plant
relationship: RO:0001000 FOODON:03411300 ! derives from onion plant

[Term]
id: FOODON:00002071
name: orange food product
is_a: FOODON:00001151 ! citrus fruit food product
intersection_of: FOODON:00001151 ! citrus fruit food product
intersection_of: RO:0001000 FOODON:03309832 ! derives from orange (raw)
relationship: RO:0001000 FOODON:03309832 ! derives from orange (raw)

[Term]
id: FOODON:00002080
name: pancake or waffle food product
is_a: FOODON:00002347 ! wheat based bakery food product
relationship: RO:0002350 FOODON:03400194 ! member of pancake or waffle (us cfr)

[Term]
id: FOODON:00002094
name: peach butter food product
is_a: FOODON:00001057 ! plant fruit food product
intersection_of: FOODON:00001057 ! plant fruit food product
intersection_of: RO:0001000 NCBITaxon:3760 ! derives from Prunus persica
relationship: RO:0001000 NCBITaxon:3760 ! derives from Prunus persica

[Term]
id: FOODON:00002095
name: peach food product
def: "A food product deriving from one or more peaches." []
is_a: FOODON:00002277 ! stone fruit food product

[Term]
id: FOODON:00002099
name: peanut food product
def: "A food product having peanuts as an ingredient." []
comment: SIREN DB annotation:\n* seed (anatomical part) FOODON:03420155
xref: https://bioregistry.io/reference/siren\:F1350
is_a: FOODON:00001172 ! nut food product
is_a: FOODON:00001264 ! legume food product
intersection_of: FOODON:00001172 ! nut food product
intersection_of: RO:0001000 NCBITaxon:3818 ! derives from Arachis hypogaea
relationship: RO:0001000 NCBITaxon:3818 ! derives from Arachis hypogaea

[Term]
id: FOODON:00002101
name: pear food product
is_a: FOODON:00001158 ! pomaceous fruit food product
intersection_of: FOODON:00001158 ! pomaceous fruit food product
intersection_of: RO:0001000 FOODON:00003041 ! derives from pear
relationship: RO:0001000 FOODON:00003041 ! derives from pear

[Term]
id: FOODON:00002111
name: pepper vegetable food product
def: "A food product deriving from one or more sweet or hot peppers." []
is_a: FOODON:00002141 ! plant fruit as vegetable food product
relationship: RO:0001000 FOODON:00003520 ! derives from pepper

[Term]
id: FOODON:00002114
name: pie food product
is_a: FOODON:00001180 ! prepared food product
is_a: FOODON:00002347 ! wheat based bakery food product
is_a: FOODON:00002644 ! food (filled)
relationship: BFO:0000051 FOODON:03306766 ! has part pie filling
relationship: BFO:0000051 FOODON:03306773 ! has part pie crust
relationship: RO:0000086 FOODON:00002407 ! has quality thickness of 1.5 cm to less than 7.0 cm

[Term]
id: FOODON:00002125
name: plant based bakery food product
is_a: FOODON:00001626 ! bakery food product
is_a: FOODON:03316579 ! multi-component plant food product
intersection_of: FOODON:00001626 ! bakery food product
intersection_of: FOODON:03316579 ! multi-component plant food product

[Term]
id: FOODON:00002126
name: plant-based candy
is_a: FOODON:00001214 ! candy food product
is_a: FOODON:03316579 ! multi-component plant food product
intersection_of: FOODON:00001214 ! candy food product
intersection_of: FOODON:03316579 ! multi-component plant food product

[Term]
id: FOODON:00002128
name: plant based gravy or sauce food product
is_a: FOODON:00001931 ! gravy or sauce

[Term]
id: FOODON:00002129
name: plant based meat product analog
is_a: FOODON:00002027 ! meat product analog
is_a: FOODON:03316579 ! multi-component plant food product
intersection_of: FOODON:00002027 ! meat product analog
intersection_of: FOODON:03316579 ! multi-component plant food product

[Term]
id: FOODON:00002131
name: plant based refined or partially-refined food product
is_a: FOODON:00002196 ! refined or partially-refined food product
relationship: RO:0002350 FOODON:03400129 ! member of refined or partially-refined food product (us cfr)

[Term]
id: FOODON:00002139
name: plant fat or oil refined food product
def: "An edible plant fat or oil product with characteristics that consumers desire such as bland flavour and odour, clear appearance, light colour, stability to oxidation and suitability for frying, and which is the result of a refining process that removes free fatty acids." []
is_a: FOODON:00001174 ! plant lipid food product
is_a: FOODON:00002131 ! plant based refined or partially-refined food product
relationship: RO:0001000 FOODON:03411017 ! derives from oil-producing plant

[Term]
id: FOODON:00002140
name: plant floret vegetable food product
is_a: FOODON:00001261 ! vegetable food product

[Term]
id: FOODON:00002141
name: plant fruit as vegetable food product
def: "A plant fruit food product which is labeled (in common language or by regulation) as a vegetable food product." []
is_a: FOODON:00001057 ! plant fruit food product
relationship: RO:0001000 FOODON:03411006 ! derives from fruit plant used as vegetable

[Term]
id: FOODON:00002142
name: plant head vegetable food product
is_a: FOODON:00001261 ! vegetable food product

[Term]
id: FOODON:00002143
name: plant leaf food product
def: "A plant food product made with plant leaves." []
is_a: FOODON:00001261 ! vegetable food product

[Term]
id: FOODON:00002146
name: plant material dressing
is_a: FOODON:00001867 ! food dressing
is_a: FOODON:03316579 ! multi-component plant food product
intersection_of: FOODON:00001867 ! food dressing
intersection_of: FOODON:03316579 ! multi-component plant food product

[Term]
id: FOODON:00002147
name: food material by consumer group
is_a: FOODON:00002403 ! food material

[Term]
id: FOODON:00002150
name: plant root vegetable food product
def: "A food product harvested from underground plant parts." []
is_a: FOODON:00001147 ! plant root food product
is_a: FOODON:00001261 ! vegetable food product
intersection_of: FOODON:00001261 ! vegetable food product
intersection_of: RO:0001000 FOODON:03420238 ! derives from root, tuber or bulb
relationship: RO:0001000 FOODON:03420238 ! derives from root, tuber or bulb

[Term]
id: FOODON:00002151
name: plant seed based bakery food product
is_a: FOODON:00001173 ! plant seed food product
is_a: FOODON:00002125 ! plant based bakery food product
intersection_of: FOODON:00001173 ! plant seed food product
intersection_of: FOODON:00002125 ! plant based bakery food product

[Term]
id: FOODON:00002152
name: plant seed cereal food product
is_a: FOODON:00001173 ! plant seed food product

[Term]
id: FOODON:00002153
name: plant seed vegetable food product
is_a: FOODON:00001173 ! plant seed food product
is_a: FOODON:00001261 ! vegetable food product
intersection_of: FOODON:00001173 ! plant seed food product
intersection_of: FOODON:00001261 ! vegetable food product
intersection_of: RO:0001000 FOODON:03411156 ! derives from pod or seed vegetable plant
relationship: RO:0001000 FOODON:03411156 ! derives from pod or seed vegetable plant

[Term]
id: FOODON:00002156
name: plant stem or spear food product
def: "A food product deriving from a plant stem or spear part." []
is_a: FOODON:00001175 ! plant stem food product
is_a: FOODON:00001261 ! vegetable food product
intersection_of: FOODON:00001175 ! plant stem food product
intersection_of: FOODON:00001261 ! vegetable food product

[Term]
id: FOODON:00002157
name: plant sweetener
is_a: FOODON:00002300 ! sweetener

[Term]
id: FOODON:00002158
name: food (preserved)
def: "Food material which is the output of a food preservation process." []
is_a: FOODON:00002645 ! food material by process

[Term]
id: FOODON:00002161
name: plum fruit food product
def: "A food product deriving from one or more plums." []
is_a: FOODON:00002277 ! stone fruit food product
relationship: RO:0001000 FOODON:00003483 ! derives from plum

[Term]
id: FOODON:00002165
name: organ meat product
is_a: FOODON:03317170 ! meat (whole or pieces)

[Term]
id: FOODON:00002180
name: pumpkin food product
def: "A food product deriving from one or more pumpkins." []
is_a: FOODON:00002141 ! plant fruit as vegetable food product
relationship: RO:0001000 FOODON:00003486 ! derives from pumpkin

[Term]
id: FOODON:00002186
name: rape fat or oil refined food product
xref: langual:thesaurus.asp?termid=H0851
is_a: FOODON:00002139 ! plant fat or oil refined food product
intersection_of: FOODON:00002139 ! plant fat or oil refined food product
intersection_of: RO:0001000 FOODON:03411248 ! derives from rapeseed plant
relationship: RO:0001000 FOODON:03411248 ! derives from rapeseed plant

[Term]
id: FOODON:00002187
name: rapeseed food product
is_a: FOODON:00002153 ! plant seed vegetable food product
is_a: FOODON:00003341 ! brassica food product
intersection_of: FOODON:00002153 ! plant seed vegetable food product
intersection_of: RO:0001000 FOODON:03411248 ! derives from rapeseed plant
relationship: RO:0001000 FOODON:03411248 ! derives from rapeseed plant

[Term]
id: FOODON:00002189
name: raspberry preserve or jam
is_a: FOODON:00001226 ! fruit preserve or jam food product
is_a: FOODON:00002190 ! raspberry food product
intersection_of: FOODON:00001226 ! fruit preserve or jam food product
intersection_of: FOODON:00002190 ! raspberry food product

[Term]
id: FOODON:00002190
name: raspberry food product
is_a: FOODON:00003028 ! bramble berry food product
intersection_of: FOODON:00001640 ! berry food product
intersection_of: RO:0001000 FOODON:03411494 ! derives from raspberry plant
relationship: RO:0001000 FOODON:03411494 ! derives from raspberry plant

[Term]
id: FOODON:00002191
name: red bell pepper food product
is_a: FOODON:00003013 ! bell pepper food product
intersection_of: FOODON:00003013 ! bell pepper food product
intersection_of: RO:0001000 FOODON:03412630 ! derives from red bell pepper plant
relationship: RO:0001000 FOODON:03412630 ! derives from red bell pepper plant

[Term]
id: FOODON:00002196
name: refined or partially-refined food product
is_a: FOODON:03311737 ! processed food

[Term]
id: FOODON:00002203
name: rice based alcoholic beverage
is_a: FOODON:00001916 ! grain based alcoholic beverage
intersection_of: FOODON:00001916 ! grain based alcoholic beverage
intersection_of: RO:0001000 FOODON:03411322 ! derives from rice plant
relationship: RO:0001000 FOODON:03411322 ! derives from rice plant

[Term]
id: FOODON:00002220
name: salmon food product
def: "A food product which has salmon as a defining ingredient." []
is_a: FOODON:00001248 ! fish food product

[Term]
id: FOODON:00002222
name: sandwich food product
def: "A sandwich food product is a food product used to create a sandwich.  This includes bread as a container, and sandwich ingredients and spreads." []
is_a: FOODON:00001180 ! prepared food product
relationship: FOODON:00001563 FOODON:00001183 ! has defining ingredient bread food product
relationship: RO:0002350 FOODON:03400218 ! member of sandwich (us cfr)

[Term]
id: FOODON:00002227
name: scallop food product
def: "A food product that is derived from some scallop." []
is_a: FOODON:00002044 ! mollusc food product
is_a: FOODON:02020804 ! scallop material
intersection_of: FOODON:00002044 ! mollusc food product
intersection_of: RO:0001000 FOODON:02020805 ! derives from scallop
relationship: RO:0001000 FOODON:02020805 ! derives from scallop

[Term]
id: FOODON:00002236
name: sheep meat food product
is_a: FOODON:00001006 ! mammalian meat food product
intersection_of: FOODON:00001006 ! mammalian meat food product
intersection_of: RO:0001000 FOODON:03411183 ! derives from sheep
relationship: RO:0001000 FOODON:03411183 ! derives from sheep

[Term]
id: FOODON:00002239
name: shrimp food product
def: "A food product that is derived from some shrimp." []
is_a: FOODON:00001792 ! crustacean food product
is_a: FOODON:02021462 ! shrimp material
intersection_of: FOODON:00001792 ! crustacean food product
intersection_of: RO:0001000 FOODON:03411237 ! derives from shrimp
relationship: RO:0001000 FOODON:03411237 ! derives from shrimp

[Term]
id: FOODON:00002250
name: sodium chloride food material
is_a: FOODON:00001714 ! food material component

[Term]
id: FOODON:00002253
name: soft drink food product
is_a: FOODON:03301977 ! beverage food product
relationship: RO:0002350 FOODON:03400241 ! member of soft drink (us cfr)

[Term]
id: FOODON:00002259
name: soy based infant food product
def: "A soybean food product designed for infants." []
is_a: FOODON:00002266 ! soybean food product
is_a: FOODON:03303130 ! infant formula
intersection_of: FOODON:00002266 ! soybean food product
intersection_of: FOODON:03303130 ! infant formula

[Term]
id: FOODON:00002260
name: soybean based meat product analog
is_a: FOODON:00002129 ! plant based meat product analog
intersection_of: FOODON:00002129 ! plant based meat product analog
intersection_of: RO:0001000 NCBITaxon:3847 ! derives from Glycine max
relationship: RO:0001000 NCBITaxon:3847 ! derives from Glycine max

[Term]
id: FOODON:00002265
name: soybean seed (field) food product
is_a: FOODON:00001173 ! plant seed food product
intersection_of: FOODON:00001173 ! plant seed food product
intersection_of: RO:0001000 NCBITaxon:3847 ! derives from Glycine max
relationship: RO:0001000 NCBITaxon:3847 ! derives from Glycine max

[Term]
id: FOODON:00002266
name: soybean food product
def: "A soybean food product is a product derived from the soybean plant." []
synonym: "soy product" EXACT []
is_a: FOODON:00001635 ! bean food product
is_a: FOODON:00002265 ! soybean seed (field) food product
intersection_of: FOODON:00001635 ! bean food product
intersection_of: RO:0001000 NCBITaxon:3847 ! derives from Glycine max

[Term]
id: FOODON:00002269
name: spinach food product
def: "A food product made from spinach." []
is_a: FOODON:00002143 ! plant leaf food product

[Term]
id: FOODON:00002271
name: squash food product
def: "A food product deriving from one or more squashes." []
is_a: FOODON:00002141 ! plant fruit as vegetable food product
relationship: RO:0001000 FOODON:00003539 ! derives from squash

[Term]
id: FOODON:00002274
name: starch refined food product
is_a: FOODON:00002131 ! plant based refined or partially-refined food product
relationship: RO:0001000 FOODON:03411016 ! derives from starch-producing plant

[Term]
id: FOODON:00002275
name: steeped beverage product
is_a: FOODON:00001253 ! plant derived beverage

[Term]
id: FOODON:00002277
name: stone fruit food product
is_a: FOODON:00001057 ! plant fruit food product

[Term]
id: FOODON:00002282
name: strawberry food product
is_a: FOODON:00001640 ! berry food product
intersection_of: FOODON:00001640 ! berry food product
intersection_of: RO:0001000 FOODON:03411393 ! derives from strawberry plant
relationship: RO:0001000 FOODON:03411393 ! derives from strawberry plant

[Term]
id: FOODON:00002283
name: strawberry preserve or jam
is_a: FOODON:00001226 ! fruit preserve or jam food product
is_a: FOODON:00002282 ! strawberry food product
intersection_of: FOODON:00001226 ! fruit preserve or jam food product
intersection_of: FOODON:00002282 ! strawberry food product

[Term]
id: FOODON:00002286
name: sugar based cacao food product
is_a: FOODON:00001015 ! plant food product

[Term]
id: FOODON:00002288
name: sugar beet sweetener food product
is_a: FOODON:03316271 ! sugar product
intersection_of: FOODON:03316271 ! sugar product
intersection_of: RO:0001000 NCBITaxon:161934 ! derives from Beta vulgaris
relationship: RO:0001000 NCBITaxon:161934 ! derives from Beta vulgaris

[Term]
id: FOODON:00002289
name: sugar beet food product
is_a: FOODON:00002150 ! plant root vegetable food product
intersection_of: FOODON:00002150 ! plant root vegetable food product
intersection_of: RO:0001000 NCBITaxon:161934 ! derives from Beta vulgaris
relationship: RO:0001000 NCBITaxon:161934 ! derives from Beta vulgaris

[Term]
id: FOODON:00002297
name: sweet potato food product
is_a: FOODON:00001146 ! solanaceous root food product
intersection_of: FOODON:00001146 ! solanaceous root food product
intersection_of: RO:0001000 FOODON:03301717 ! derives from sweet potato (raw)
relationship: RO:0001000 FOODON:03301717 ! derives from sweet potato (raw)

[Term]
id: FOODON:00002300
name: sweetener
xref: langual:thesaurus.asp?termid=H0202
is_a: FOODON:00001133 ! condiment
is_a: FOODON:00001857 ! food flavoring or seasoning

[Term]
id: FOODON:00002301
name: pork cured meat food product
is_a: FOODON:00001039 ! cured meat food product
is_a: FOODON:00001241 ! processed pork meat food product
intersection_of: FOODON:00001038 ! pork meat food product
intersection_of: FOODON:00001039 ! cured meat food product

[Term]
id: FOODON:00002306
name: swine sausage
is_a: FOODON:00001132 ! swine food product
is_a: FOODON:03310675 ! luncheon meat
intersection_of: FOODON:00001605 ! animal product sausage
intersection_of: RO:0001000 FOODON:03411136 ! derives from swine

[Term]
id: FOODON:00002307
name: swordfish food product
is_a: FOODON:00001248 ! fish food product
is_a: FOODON:02021997 ! swordfish material

[Term]
id: FOODON:00002314
name: tomato based gravy or sauce food product
is_a: FOODON:00002329 ! vegetable based gravy or sauce food product
relationship: FOODON:00001563 FOODON:00002318 ! has defining ingredient tomato (whole or pieces)

[Term]
id: FOODON:00002315
name: tomato condiment
def: "A condiment which has tomato as a defining ingredient." []
is_a: FOODON:00001133 ! condiment

[Term]
id: FOODON:00002316
name: tomato juice food product
is_a: FOODON:00001164 ! tomato food product
is_a: FOODON:03301444 ! vegetable juice food product
intersection_of: FOODON:00001164 ! tomato food product
intersection_of: FOODON:03301444 ! vegetable juice food product

[Term]
id: FOODON:00002318
name: tomato (whole or pieces)
def: "A whole tomato or some substance made from a processed tomato." []
synonym: "tomato" EXACT []
is_a: FOODON:00001164 ! tomato food product
relationship: RO:0001000 FOODON:03309927 ! derives from tomato (raw)

[Term]
id: FOODON:00002320
name: tuna food product
is_a: FOODON:00001248 ! fish food product
relationship: RO:0001000 FOODON:03411269 ! derives from tuna

[Term]
id: FOODON:00002326
name: uncured cheese food product
is_a: FOODON:00001013 ! cheese food product
relationship: RO:0002350 FOODON:03400185 ! member of uncured cheese (us cfr)

[Term]
id: FOODON:00002327
name: uncured cow milk cheese food product
is_a: FOODON:00001127 ! cow milk cheese
is_a: FOODON:00002326 ! uncured cheese food product

[Term]
id: FOODON:00002328
name: vanilla bean food product
def: "A vanilla bean food product is derived from the fruit, a seed capsule, of a vanilla plant." []
synonym: "vanilla" EXACT []
is_a: FOODON:00001173 ! plant seed food product
is_a: FOODON:03303380 ! spice food product
intersection_of: FOODON:03303380 ! spice food product
intersection_of: RO:0001000 FOODON:00003738 ! derives from vanilla bean
relationship: RO:0001000 FOODON:00003738 ! derives from vanilla bean

[Term]
id: FOODON:00002329
name: vegetable based gravy or sauce food product
is_a: FOODON:00002128 ! plant based gravy or sauce food product

[Term]
id: FOODON:00002336
name: vitamin and mineral food supplement food product
is_a: FOODON:00001874 ! food supplement

[Term]
id: FOODON:00002337
name: vitamin as food supplement food product
is_a: FOODON:00002336 ! vitamin and mineral food supplement food product

[Term]
id: FOODON:00002338
name: walnut food product
comment: A food product derived from one or more walnuts.
is_a: FOODON:00001172 ! nut food product

[Term]
id: FOODON:00002339
name: water based soft drink food product
is_a: FOODON:00002253 ! soft drink food product
relationship: RO:0001000 ENVO:00003064 ! derives from drinking water

[Term]
id: FOODON:00002340
name: water food product
def: "A water food product is a food product derived from H20 (water) in its liquid form." []
comment: SIREN DB annotation:\n* liquid, low viscosity, with no visible particles FOODON:03430123\n* not heat-treated FOODON:03440003
xref: https://bioregistry.io/reference/siren\:F10414
is_a: FOODON:03301977 ! beverage food product
relationship: RO:0001000 ENVO:00002011 ! derives from fresh water
relationship: RO:0002350 FOODON:03400112 ! member of nonalcoholic beverage (us cfr)

[Term]
id: FOODON:00002343
name: watermelon food product
is_a: FOODON:00001154 ! citrullus lanatus fruit food product

[Term]
id: FOODON:00002347
name: wheat based bakery food product
is_a: FOODON:00001917 ! grain based bakery food product
intersection_of: FOODON:00001917 ! grain based bakery food product
intersection_of: RO:0001000 FOODON:03411312 ! derives from wheat plant
relationship: RO:0001000 FOODON:03411312 ! derives from wheat plant

[Term]
id: FOODON:00002350
name: wheat based pastry food product
is_a: FOODON:00002347 ! wheat based bakery food product
relationship: FOODON:00002420 FOODON:00001210 ! has ingredient wheat flour food product

[Term]
id: FOODON:00002351
name: wheat bread food product
def: "A bread food product which has wheat as a defining ingredient." []
is_a: FOODON:00001183 ! bread food product
is_a: FOODON:00003395 ! multi-component wheat food product

[Term]
id: FOODON:00002352
name: wheat cereal food product
is_a: FOODON:00001709 ! cereal food product
intersection_of: FOODON:00001709 ! cereal food product
intersection_of: RO:0001000 FOODON:03411312 ! derives from wheat plant
relationship: RO:0001000 FOODON:03411312 ! derives from wheat plant

[Term]
id: FOODON:00002353
name: wheat cracker food product
is_a: FOODON:00002347 ! wheat based bakery food product

[Term]
id: FOODON:00002356
name: wheat based snack food product
is_a: FOODON:00003395 ! multi-component wheat food product
is_a: FOODON:03315013 ! snack food

[Term]
id: FOODON:00002364
name: wine or wine-like food product
is_a: FOODON:00001094 ! fermented beverage

[Term]
id: FOODON:00002368
name: yam food product
is_a: FOODON:00002150 ! plant root vegetable food product
intersection_of: FOODON:00002150 ! plant root vegetable food product
intersection_of: RO:0001000 NCBITaxon:4672 ! derives from Dioscorea
relationship: RO:0001000 NCBITaxon:4672 ! derives from Dioscorea

[Term]
id: FOODON:00002373
name: food by meal type
def: "A meal type is the name of an eating occasion that may have location, food type, or other customary contextual features. (Damion's 1st draft definition)" []
is_a: FOODON:00002403 ! food material

[Term]
id: FOODON:00002386
name: breakfast food
def: "A food product traditionally consumed during breakfast." []
is_a: FOODON:00002373 ! food by meal type

[Term]
id: FOODON:00002396
name: synthetic vanilla extract
def: "Synthetic vanilla is a compound made of vanillin or ethyl vanillin" []
synonym: "artificial vanilla" EXACT []
synonym: "synthetic vanillin" EXACT []
synonym: "vanillin" EXACT []
is_a: FOODON:03412972 ! food additive
relationship: FOODON:00001301 FOODON:03316764 ! has food substance analog vanilla bean extract

[Term]
id: FOODON:00002403
name: food material
def: "Any substance that can be consumed by an organism to satisfy nutritional or other health needs, or to provide a social or organoleptic food experience" []
comment: This class is the top of FOODON's main food product hierarchy which is described in the https://www.foodon.org website, and can be searched in lookup services like https://www.ebi.ac.uk/ols/
synonym: "food" EXACT []
synonym: "foodstuff" EXACT []
is_a: ENVO:00010483 ! environmental material

[Term]
id: FOODON:00002407
name: thickness of 1.5 cm to less than 7.0 cm
def: "A material entity having a thickness of 1.5 to less than 7.0 cm" []
is_a: PATO:0000915 ! thickness

[Term]
id: FOODON:00002414
name: food solvent extraction
def: "Extraction of substance(s) from a food source using a solvent such as alcohol, hexane, or ethanol." []
is_a: FOODON:03460130 ! physical/chemical modification process

[Term]
id: FOODON:00002419
name: food evaporation process
def: "A food evaporation process is the process of removing water from a food." []
is_a: FOODON:03460130 ! physical/chemical modification process

[Term]
id: FOODON:00002448
name: zucchini food product
def: "A zucchini food product is a food product deriving from either golden or green zucchini plant cultivars." []
is_a: FOODON:00002271 ! squash food product

[Term]
id: FOODON:00002450
name: multi-component honey product
is_a: FOODON:00001178 ! honey food product
is_a: FOODON:00002501 ! multi-component food
intersection_of: FOODON:00001178 ! honey food product
intersection_of: FOODON:00002501 ! multi-component food

[Term]
id: FOODON:00002451
name: food transformation process
def: "A process involving the physical transformation of a food source or food product into some derived organic material or food product" []
is_a: BFO:0000015 ! process

[Term]
id: FOODON:00002452
name: invertebrate animal
def: "Invertebrates are animals that neither possess nor develop a vertebral column (commonly known as a backbone or spine), derived from the notochord. This includes all animals apart from the subphylum Vertebrata." []
is_a: FOODON:00003004 ! animal
is_a: FOODON:00005522 ! invertebrate material

[Term]
id: FOODON:00002454
name: food material by characteristic
def: "Food material which has been categorized by a characteristic such as granularity or temperature." []
comment: This term was renamed from "food product by quality" to align better with COB "characteristic" label, and as well to disambiguate from other use of "quality" as a food grading. This term is useful for tasks like food inspection where little prior knowledge of how the food came to be is available. Some terms like "food (frozen)"are both a quality descriptor and the output of a process.
is_a: FOODON:00002403 ! food material

[Term]
id: FOODON:00002456
name: food (baked)
def: "Food material which is baked." []
synonym: "baked" EXACT []
synonym: "baked food product" EXACT []
is_a: FOODON:00001181 ! food (cooked)
intersection_of: FOODON:00001181 ! food (cooked)
intersection_of: RO:0002353 FOODON:03450005 ! output of food baking
relationship: RO:0002353 FOODON:03450005 ! output of food baking

[Term]
id: FOODON:00002470
name: food material characteristic
def: "A physical object quality which describes a characteristic of some food material." []
is_a: PATO:0001241 ! physical object quality

[Term]
id: FOODON:00002473
name: apple
def: "A pome fruit of an apple tree (Malus domestica)." []
comment: A whole apple may include a stem.
is_a: FOODON:03310788 ! apple (whole or pieces)
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0001000 FOODON:03411599 ! derives from pome fruit plant
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3750 ! in taxon Malus domestica

[Term]
id: FOODON:00002474
name: sheep milk (raw)
def: "Raw sheep milk." []
is_a: ENVO:01000815 ! liquid environmental material
is_a: FOODON:00001112 ! ovine dairy food product
is_a: FOODON:02010013 ! animal milk (raw)
is_a: FOODON:02021254 ! sheep milk
intersection_of: FOODON:02021254 ! sheep milk
intersection_of: RO:0000086 FOODON:00004348 ! has quality raw

[Term]
id: FOODON:00002482
name: apple (sliced)
is_a: FOODON:03310788 ! apple (whole or pieces)

[Term]
id: FOODON:00002485
name: peach (whole or pieces)
is_a: FOODON:00002095 ! peach food product

[Term]
id: FOODON:00002486
name: apricot (whole or pieces)
is_a: FOODON:00001615 ! apricot food product

[Term]
id: FOODON:00002488
name: pear (whole or pieces)
is_a: FOODON:00002101 ! pear food product

[Term]
id: FOODON:00002498
name: chard food product
def: "A food product made from a chard plant cultivar." []
is_a: FOODON:00002143 ! plant leaf food product

[Term]
id: FOODON:00002501
name: multi-component food
def: "A food product consisting of food material derived from ingredients sourced from multiple organisms." []
comment: The definition of this is being discussed in issue: https://github.com/FoodOntology/foodon/issues/57\n\nNamely, how to characterize the threshold of ingredients that make for multi-component classification? Salt, pepper, spices wouldn't normally make a food multi-component?
is_a: FOODON:00001002 ! food product
relationship: RO:0002350 FOODON:03400139 ! member of multicomponent meal (us cfr)

[Term]
id: FOODON:00002502
name: ham food product
def: "Ham is pork from a leg cut that has been preserved by wet or dry curing, with or without smoking.  As a processed meat, the term \"ham\" includes both whole cuts of meat and ones that have been mechanically formed." []
synonym: "ham" EXACT []
is_a: FOODON:00001038 ! pork meat food product

[Term]
id: FOODON:00002505
name: dairy cattle
def: "Dairy cattle are a type of cattle bred for the ability to produce large quantities of milk, from which dairy products are made.  This class covers both male and female members of a dairy breed." []
is_a: FOODON:00002507 ! taurine cattle

[Term]
id: FOODON:00002507
name: taurine cattle
def: "Taurine cattle (Bos taurus taurus), also called European cattle, are a subspecies of domesticated cattle originating in the Near East. Both taurine cattle and indicine cattle (zebus) are descended from the aurochs. Taurine cattle were originally considered a distinct species, but are now typically grouped with zebus and aurochs into one species, Bos taurus. Most modern breeds of cattle are taurine cattle." []
xref: langual:thesaurus.asp?termid=B5186
is_a: NCBITaxon:9913 ! Bos taurus

[Term]
id: FOODON:00002511
name: navel orange (raw)
synonym: "navel orange" EXACT []
is_a: FOODON:03309832 ! orange (raw)

[Term]
id: FOODON:00002515
name: carrot cake
def: "Carrot cake is a cake that contains carrots mixed into the batter." []
is_a: FOODON:00001278 ! cake food product
is_a: FOODON:00001687 ! carrot food product
intersection_of: FOODON:00001278 ! cake food product
intersection_of: FOODON:00001687 ! carrot food product

[Term]
id: FOODON:00002562
name: chocolate brownie
def: "A chocolate brownie (commonly referred to as simply brownie) is a square, baked, chocolate dessert." []
is_a: FOODON:00001278 ! cake food product

[Term]
id: FOODON:00002576
name: bean sprout
def: "A bean sprout is a germinated bean to be eaten raw or cooked." []
is_a: FOODON:00001635 ! bean food product
is_a: FOODON:03411567 ! bean plant
is_a: FOODON:03420183 ! sprout
intersection_of: FOODON:03411567 ! bean plant
intersection_of: FOODON:03420183 ! sprout

[Term]
id: FOODON:00002581
name: aquatic invertebrate
def: "An aquatic invertebrate may live entirely beneath the water, or may live upon its surface or on the plants surrounding it. Some breathe air, others breathe water. To move, they may walk, swim, float, skate, fly or glide on their bellies—or they may not move much at all." []
is_a: FOODON:00002452 ! invertebrate animal
is_a: FOODON:00005683 ! aquatic invertebrate material

[Term]
id: FOODON:00002616
name: avian animal
def: "A whole avian animal." []
comment: An avian animal which is dead or alive and has a relatively intact body.
synonym: "Aves" EXACT []
synonym: "avian" EXACT []
synonym: "bird" EXACT []
is_a: FOODON:03411297 ! vertebrate animal
intersection_of: FOODON:03411297 ! vertebrate animal
intersection_of: RO:0002162 NCBITaxon:8782 ! in taxon Aves
relationship: RO:0002162 NCBITaxon:8782 ! in taxon Aves

[Term]
id: FOODON:00002644
name: food (filled)
def: "Food material which contains an outer layer and inner core of different food materials, and which is the output of a food filling process." []
is_a: FOODON:00002645 ! food material by process
intersection_of: FOODON:00002645 ! food material by process
intersection_of: RO:0002353 FOODON:03460207 ! output of food filling process
relationship: RO:0002353 FOODON:03460207 ! output of food filling process

[Term]
id: FOODON:00002645
name: food material by process
def: "Food material organized by the process which it results from." []
is_a: FOODON:00002403 ! food material

[Term]
id: FOODON:00002663
name: pig food product
def: "A food product that is derived from some pig." []
is_a: FOODON:00001132 ! swine food product
is_a: FOODON:02021649 ! pig material

[Term]
id: FOODON:00002664
name: lipid food product
def: "A lipid food product is a food product made primarily of plant or animal fat or oil" []
synonym: "fats and oils" EXACT []
synonym: "oils and fats" EXACT []
is_a: FOODON:03420228 ! extract, concentrate or isolate of plant or animal
relationship: RO:0001000 CHEBI:18059 ! derives from lipid

[Term]
id: FOODON:00002665
name: quick bread
def: "Quick bread is any bread leavened with leavening agents other than yeast or eggs." []
is_a: FOODON:00001183 ! bread food product

[Term]
id: FOODON:00002671
name: animal meat food product
is_a: FOODON:00004242 ! animal food product
relationship: RO:0002350 FOODON:03400217 ! member of meat, poultry, seafood or related product (us cfr)

[Term]
id: FOODON:00002673
name: piece of chicken skin
def: "A piece of chicken skin." []
is_a: FOODON:02010075 ! piece of animal skin
is_a: FOODON:02020177 ! chicken organ
is_a: FOODON:02020189 ! piece of chicken organ
intersection_of: FOODON:02010075 ! piece of animal skin
intersection_of: RO:0002162 NCBITaxon:9031 ! in taxon Gallus gallus

[Term]
id: FOODON:00002681
name: milk fat
is_a: FOODON:03303837 ! cow butterfat food product

[Term]
id: FOODON:00002684
name: mustard greens
def: "Mustard greens are leaves from a mustard plant" []
is_a: FOODON:00002053 ! mustard food product
is_a: FOODON:00002143 ! plant leaf food product

[Term]
id: FOODON:00002705
name: chicken liver
def: "A whole animal liver that is obtained from a chicken." []
is_a: FOODON:02010045 ! animal liver
is_a: FOODON:02020177 ! chicken organ
intersection_of: FOODON:02010045 ! animal liver
intersection_of: RO:0002162 NCBITaxon:9031 ! in taxon Gallus gallus

[Term]
id: FOODON:00002710
name: beef lung (raw)
def: "A raw lung that is obtained from a beef." []
comment: Cow lung is used in various cuisines and as a source for pulmonary surfactants. In Peru it is known as bofe. In Southeast Asia, Nasi kuning can be made with cow lung. Paru goreng is fried cow lung Padang food. It is a type of offal. In Indonesia, cow's lung is called paru [wikipedia].
synonym: "bofe" EXACT []
synonym: "cow lung" EXACT []
synonym: "cow lung (raw)" EXACT []
synonym: "paru" EXACT []
is_a: FOODON:00002824 ! lung (raw)
is_a: FOODON:02010064 ! animal lung (raw)
is_a: FOODON:02020915 ! beef lung
is_a: FOODON:02020921 ! beef organ (raw)
intersection_of: FOODON:02020915 ! beef lung
intersection_of: RO:0000086 FOODON:00004348 ! has quality raw

[Term]
id: FOODON:00002711
name: cracker
def: "A cracker is a flat, dry baked food typically made with flour. In UK English, crackers are sometimes called water biscuits, savoury biscuits or biscuits." []
synonym: "savoury biscuit" EXACT []
synonym: "water biscuit" EXACT []
is_a: FOODON:00001917 ! grain based bakery food product
relationship: RO:0002350 FOODON:03400242 ! member of cracker (us cfr)

[Term]
id: FOODON:00002728
name: Kielbasa
def: "Kielbasa (from Polish kiełbasa)[a] is any type of meat sausage from Poland, and a staple of Polish cuisine." []
synonym: "polish sausage" EXACT []
is_a: FOODON:00001605 ! animal product sausage

[Term]
id: FOODON:00002729
name: pork sausage
def: "Pork sausage is sausage made with pork meat." []
is_a: FOODON:00002306 ! swine sausage
intersection_of: FOODON:00002306 ! swine sausage
intersection_of: RO:0001000 FOODON:03309969 ! derives from pork (ground or minced)
relationship: RO:0001000 FOODON:03309969 ! derives from pork (ground or minced)

[Term]
id: FOODON:00002737
name: beef hamburger (dish)
def: "A hamburger (short: burger) is a sandwich consisting of one or more cooked patties of ground meat, usually beef, placed inside a sliced bread roll or bun. The patty may be pan fried, grilled, or flame broiled." []
synonym: "burger" EXACT []
synonym: "hamburger" EXACT []
is_a: FOODON:00001699 ! cattle sandwich
is_a: FOODON:00003288 ! multi-component meat product
relationship: FOODON:00001563 FOODON:03317337 ! has defining ingredient ground beef patty

[Term]
id: FOODON:00002743
name: roll or bun
def: "A roll is a small, often round loaf of bread served as a meal accompaniment (eaten plain or with butter).  A bun is a small, sometimes sweet, bread, or bread roll." []
synonym: "bread roll" EXACT []
synonym: "bun" EXACT []
synonym: "roll" EXACT []
is_a: FOODON:00001183 ! bread food product

[Term]
id: FOODON:00002752
name: bean (dried)
def: "A whole dried bean is a bean resulting from natural or mechanical air drying applied to a bean or bean pod." []
synonym: "dried bean" EXACT []
is_a: FOODON:00002753 ! bean
is_a: FOODON:03307539 ! food (dried)
intersection_of: FOODON:00002753 ! bean
intersection_of: FOODON:03307539 ! food (dried)

[Term]
id: FOODON:00002753
name: bean
def: "A seed of a bean plant from one of several genera of the flowering plant family (Fabaceae)." []
is_a: FOODON:00001635 ! bean food product
is_a: FOODON:03310646 ! legume
relationship: RO:0002162 FOODON:03411567 ! in taxon bean plant

[Term]
id: FOODON:00002762
name: bean (cooked)
def: "Bean material which has been cooked." []
is_a: FOODON:00001181 ! food (cooked)
is_a: FOODON:03301467 ! bean (whole or pieces)
intersection_of: FOODON:00001181 ! food (cooked)
intersection_of: FOODON:03301467 ! bean (whole or pieces)

[Term]
id: FOODON:00002765
name: bean pod
def: "A bean pod is a fruit pod from a bean plant" []
is_a: FOODON:00002576 ! bean sprout
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0001000 FOODON:03411567 ! derives from bean plant
relationship: RO:0002162 NCBITaxon:3885 ! in taxon Phaseolus vulgaris

[Term]
id: FOODON:00002766
name: green bean (whole pod or pieces)
def: "A green bean food product that derives from raw whole green bean pods." []
is_a: FOODON:00001934 ! green bean food product
intersection_of: FOODON:00001934 ! green bean food product
intersection_of: RO:0001000 FOODON:03305806 ! derives from green bean pod
relationship: RO:0001000 FOODON:03305806 ! derives from green bean pod

[Term]
id: FOODON:00002776
name: lima bean (whole pod or pieces)
is_a: FOODON:00002000 ! lima bean food product
is_a: FOODON:03301467 ! bean (whole or pieces)
intersection_of: FOODON:00002000 ! lima bean food product
intersection_of: RO:0001000 FOODON:03302053 ! derives from lima bean
relationship: RO:0001000 FOODON:03302053 ! derives from lima bean

[Term]
id: FOODON:00002787
name: vetch food product
is_a: FOODON:00002153 ! plant seed vegetable food product
relationship: RO:0001000 FOODON:03412070 ! derives from vetch plant

[Term]
id: FOODON:00002791
name: vetch seed
def: "A seed of a vetch plant." []
is_a: FOODON:00002787 ! vetch food product
is_a: FOODON:03310646 ! legume
relationship: RO:0002162 NCBITaxon:3904 ! in taxon Vicia

[Term]
id: FOODON:00002796
name: potato (whole or pieces)
def: "A potato substance is a whole potato transformed into some derivative food material. It doesn't include potato food products that are ready to consume or simply require thawing or reheating." []
is_a: FOODON:00001148 ! potato food product

[Term]
id: FOODON:00002797
name: potato prepared food
is_a: FOODON:00001148 ! potato food product

[Term]
id: FOODON:00002808
name: olive oil (extra-virgin)
def: "Extra virgin olive oil is a virgin olive oil which has a free acidity, expressed as oleic acid, of not more than 0.8 grams per 100 grams." []
synonym: "extra virgin olive oil" EXACT []
synonym: "IAO:0000122" EXACT []
is_a: FOODON:03306633 ! olive oil (virgin)

[Term]
id: FOODON:00002811
name: broad bean pod
synonym: "fava bean pod" EXACT []
is_a: FOODON:00001665 ! broad bean food product
is_a: FOODON:00002765 ! bean pod
intersection_of: FOODON:00002765 ! bean pod
intersection_of: RO:0001000 FOODON:03411367 ! derives from broad bean plant

[Term]
id: FOODON:00002812
name: edible bean pod
def: "A bean pod which is still tender rather than one that has reached full maturity." []
is_a: FOODON:00002765 ! bean pod

[Term]
id: FOODON:00002813
name: pea food product
is_a: FOODON:00001264 ! legume food product
intersection_of: FOODON:00001264 ! legume food product
intersection_of: RO:0001000 FOODON:03411338 ! derives from pea plant
relationship: RO:0001000 FOODON:03411338 ! derives from pea plant

[Term]
id: FOODON:00002815
name: lowfat cow milk (1% fat)
synonym: "1% milk" EXACT []
is_a: FOODON:03301483 ! lowfat cow milk

[Term]
id: FOODON:00002816
name: lima bean (raw)
is_a: FOODON:03301403 ! bean (raw)
is_a: FOODON:03302053 ! lima bean
intersection_of: FOODON:03301403 ! bean (raw)
intersection_of: FOODON:03302053 ! lima bean

[Term]
id: FOODON:00002818
name: broad bean (raw)
is_a: FOODON:03301227 ! broad bean
is_a: FOODON:03301403 ! bean (raw)
intersection_of: FOODON:03301227 ! broad bean
intersection_of: FOODON:03301403 ! bean (raw)

[Term]
id: FOODON:00002819
name: liver food product
def: "A liver food product is a food product that derives from one or more liver organs." []
is_a: FOODON:00002165 ! organ meat product
intersection_of: FOODON:00002165 ! organ meat product
intersection_of: RO:0001000 FOODON:03309772 ! derives from liver (raw)
relationship: RO:0001000 FOODON:03309772 ! derives from liver (raw)

[Term]
id: FOODON:00002822
name: lung food product
def: "A lung food product is a food product that derivers from one or more mammalian lungs." []
is_a: FOODON:00002165 ! organ meat product
intersection_of: FOODON:00002165 ! organ meat product
intersection_of: RO:0001000 FOODON:00002824 ! derives from lung (raw)
relationship: RO:0001000 FOODON:00002824 ! derives from lung (raw)

[Term]
id: FOODON:00002823
name: sheep lung (raw)
def: "A raw lung that is obtained from a sheep." []
synonym: "sheep lung" EXACT []
is_a: FOODON:00002824 ! lung (raw)
is_a: FOODON:02010064 ! animal lung (raw)
is_a: FOODON:02021264 ! piece of sheep (raw)
is_a: FOODON:02021274 ! sheep lung
intersection_of: FOODON:02021274 ! sheep lung
intersection_of: RO:0000086 FOODON:00004348 ! has quality raw

[Term]
id: FOODON:00002824
name: lung (raw)
def: "A whole raw lung is a whole lung organ obtained from an animal during a butchery process." []
is_a: FOODON:00002822 ! lung food product
is_a: FOODON:03311126 ! food (raw)
is_a: UBERON:0002048 ! lung
intersection_of: FOODON:00002822 ! lung food product
intersection_of: FOODON:03311126 ! food (raw)
intersection_of: UBERON:0002048 ! lung
intersection_of: RO:0000086 FOODON:03430150 ! has quality whole, natural shape
relationship: RO:0000086 FOODON:03430150 ! has quality whole, natural shape

[Term]
id: FOODON:00002825
name: lamb kidney (raw)
def: "A raw kidney that is obtained from a lamb." []
comment: Lamb kidneys are found in many cuisines across Europe and the Middle East, often split into two halves and grilled (on kebabs in the Middle East), or sautéed in a sauce. They are generally the most highly regarded of all kidneys. [https://en.wikipedia.org/wiki/Lamb_and_mutton]
is_a: FOODON:02021150 ! lamb kidney
is_a: FOODON:02021158 ! lamb organ (raw)
is_a: FOODON:03310042 ! sheep kidney (raw)
intersection_of: FOODON:02021150 ! lamb kidney
intersection_of: RO:0000086 FOODON:00004348 ! has quality raw

[Term]
id: FOODON:00002827
name: sheep liver (raw)
def: "A raw liver that is obtained from a sheep." []
is_a: FOODON:00002236 ! sheep meat food product
is_a: FOODON:02010062 ! animal liver (raw)
is_a: FOODON:02021264 ! piece of sheep (raw)
is_a: FOODON:02021273 ! sheep liver
is_a: FOODON:03309772 ! liver (raw)
intersection_of: FOODON:02021273 ! sheep liver
intersection_of: RO:0000086 FOODON:00004348 ! has quality raw

[Term]
id: FOODON:00002836
name: lamb neck
def: "A whole neck that is obtained from a lamb." []
synonym: "neck of lamb" EXACT []
is_a: FOODON:00001992 ! lamb meat food product
is_a: FOODON:02010128 ! animal neck
is_a: FOODON:02021189 ! piece of lamb meat
intersection_of: FOODON:02010128 ! animal neck
intersection_of: RO:0002162 FOODON:03411669 ! in taxon lamb

[Term]
id: FOODON:00002842
name: Williams bon chrétien pear plant
def: "The Williams' bon chrétien pear, commonly called the Williams pear or the Bartlett pear in the United States and Canada, is the most commonly grown variety of pear in most countries outside Asia." []
is_a: FOODON:03411344 ! pear plant

[Term]
id: FOODON:00002843
name: Williams pear (raw)
def: "The most commonly grown variety of pear fruit in most countries outside Asia." []
synonym: "Bartlett pear" EXACT []
synonym: "Williams bon chrétien pear" EXACT []
is_a: FOODON:03301724 ! pear (raw)
intersection_of: FOODON:03301724 ! pear (raw)
intersection_of: RO:0001000 FOODON:00002842 ! derives from Williams bon chrétien pear plant
relationship: RO:0001000 FOODON:00002842 ! derives from Williams bon chrétien pear plant

[Term]
id: FOODON:00002958
name: beef sausage
def: "Beef sausage is sausage primarily made of beef." []
is_a: FOODON:00001700 ! cattle sausage food product

[Term]
id: FOODON:00002987
name: tuna steak
def: "A tuna steak is a cut of fish from a tuna." []
synonym: "tuna cutlet" EXACT []
is_a: FOODON:00002320 ! tuna food product

[Term]
id: FOODON:00003004
name: animal
def: "A whole animal." []
comment: A whole animal can be dead or alive, but its body must be relatively intact.
xref: langual:thesaurus.asp?termid=B1297
is_a: FOODON:03420164 ! animal material
is_a: UBERON:0000468 ! multicellular organism
intersection_of: UBERON:0000468 ! multicellular organism
intersection_of: RO:0002162 NCBITaxon:33208 ! in taxon Metazoa

[Term]
id: FOODON:00003013
name: bell pepper food product
def: "A bell pepper is a fruits in different colours - including red, yellow, orange, green, white, and purple - from a bell pepper plant cultivar.  Bell peppers are sometimes grouped with less pungent pepper varieties as \"sweet peppers\"." []
is_a: FOODON:00002111 ! pepper vegetable food product
intersection_of: FOODON:00002111 ! pepper vegetable food product
intersection_of: RO:0001000 FOODON:03412628 ! derives from bell pepper plant
relationship: RO:0001000 FOODON:03412628 ! derives from bell pepper plant

[Term]
id: FOODON:00003014
name: golden zucchini plant
def: "Golden zucchini is a modern hybrid summer squash (Cucurbita pepo)." []
synonym: "gold gush zucchini" EXACT []
synonym: "golden delight zucchini" EXACT []
synonym: "goldfinger zucchini" EXACT []
synonym: "yellow zucchini" EXACT []
is_a: FOODON:03411190 ! summer squash cultivar

[Term]
id: FOODON:00003015
name: golden zucchini squash
def: "A golden or yellow zucchini is a summer squash harvested from the golden zucchini cultivar." []
synonym: "golden zucchini" EXACT []
synonym: "yellow zucchini" EXACT []
is_a: FOODON:00002448 ! zucchini food product
intersection_of: FOODON:00002448 ! zucchini food product
intersection_of: RO:0001000 FOODON:00003014 ! derives from golden zucchini plant
relationship: RO:0001000 FOODON:00003014 ! derives from golden zucchini plant

[Term]
id: FOODON:00003026
name: drupelet berry food product
def: "A drupelet berry food product is a product made from aggregated drupelet \"berries\" such as Raspberries and Blackberries." []
synonym: "druplet berry" EXACT []
is_a: FOODON:00001640 ! berry food product

[Term]
id: FOODON:00003028
name: bramble berry food product
is_a: FOODON:00001640 ! berry food product
intersection_of: FOODON:00001640 ! berry food product
intersection_of: RO:0001000 FOODON:03411121 ! derives from bramble berry plant
relationship: RO:0001000 FOODON:03411121 ! derives from bramble berry plant

[Term]
id: FOODON:00003041
name: pear
def: "A pome fruit of a pear tree." []
is_a: FOODON:00002488 ! pear (whole or pieces)
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0001000 FOODON:03411599 ! derives from pome fruit plant
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3766 ! in taxon Pyrus

[Term]
id: FOODON:00003042
name: herb food product
def: "A leaf of a plant that is used for flavoring." []
is_a: FOODON:00001242 ! spice or herb

[Term]
id: FOODON:00003060
name: pita bread
def: "Pita is a family of yeast-leavened round flatbreads baked from wheat flour, common in the Mediterranean, Middle East, and neighboring areas." []
synonym: "pita" EXACT []
synonym: "pitta" EXACT []
is_a: FOODON:00001183 ! bread food product

[Term]
id: FOODON:00003064
name: watercress
is_a: FOODON:00002143 ! plant leaf food product
intersection_of: FOODON:00002143 ! plant leaf food product
intersection_of: RO:0001000 FOODON:03411492 ! derives from watercress plant
relationship: RO:0001000 FOODON:03411492 ! derives from watercress plant

[Term]
id: FOODON:00003130
name: gai lan
def: "Gai lan is the leaf and stem component of the gai lan plant" []
synonym: "chinese broccoli" EXACT []
synonym: "chinese kale" EXACT []
synonym: "jie lan" EXACT []
synonym: "kai-lan" EXACT []
is_a: FOODON:00002143 ! plant leaf food product
intersection_of: FOODON:00002143 ! plant leaf food product
intersection_of: RO:0001000 NCBITaxon:3712 ! derives from Brassica oleracea
relationship: RO:0001000 NCBITaxon:3712 ! derives from Brassica oleracea

[Term]
id: FOODON:00003157
name: almond milk
def: "Almond milk is a plant milk manufactured from almonds with a creamy texture and nutty flavor," []
is_a: FOODON:00001587 ! almond food product

[Term]
id: FOODON:00003158
name: poultry sandwich
def: "A poultry sandwich contains chicken, turkey or other poultry meat." []
is_a: FOODON:00001604 ! animal product sandwich

[Term]
id: FOODON:00003163
name: piece(s) of chicken
def: "One or more pieces of chickens." []
is_a: FOODON:02020150 ! chicken material
is_a: FOODON:02020715 ! piece(s) of poultry
intersection_of: BFO:0000027 ! object aggregate
intersection_of: RO:0002351 FOODON:02020171 ! has member piece of chicken
relationship: RO:0002351 FOODON:02020171 ! has member piece of chicken

[Term]
id: FOODON:00003177
name: vegetarian burger
def: "A burger patty that does not contain meat or any such kind of meat. These burgers may be made from ingredients like beans, especially soybeans and tofu, nuts, grains, seeds or fungi such as mushrooms or mycoprotein." []
synonym: "veggie burger" EXACT []
is_a: FOODON:00002129 ! plant based meat product analog
relationship: RO:0001000 FOODON:03411049 ! derives from protein-producing plant

[Term]
id: FOODON:00003194
name: vegetarian food material
def: "A food product not including meat and animal tissue products (such as gelatin or animal-derived rennet)." []
synonym: "vegetarian food" EXACT []
is_a: FOODON:00002147 ! food material by consumer group

[Term]
id: FOODON:00003205
name: peanut (whole or pieces)
is_a: FOODON:00002099 ! peanut food product

[Term]
id: FOODON:00003206
name: peanut
def: "A seed of a peanut plant (Arachis hypogaea)." []
is_a: FOODON:00002099 ! peanut food product
is_a: FOODON:03310646 ! legume
relationship: RO:0002162 NCBITaxon:3818 ! in taxon Arachis hypogaea

[Term]
id: FOODON:00003208
name: miso
def: "A traditional Japanese seasoning produced by fermenting soybeans with salt and kōji (the fungus Aspergillus oryzae) and sometimes rice, barley, seaweed or other ingredients." []
is_a: FOODON:00001070 ! miso food product
relationship: FOODON:00001563 FOODON:03301415 ! has defining ingredient soybean

[Term]
id: FOODON:00003237
name: skim milk (liquid)
is_a: FOODON:03301484 ! skim milk food product
is_a: FOODON:03302116 ! cow milk (liquid)

[Term]
id: FOODON:00003281
name: whitefish (fisheries term)
def: "A fisheries term for several species of demersal fish with fins, particularly Atlantic cod (Gadus morhua), whiting (Merluccius bilinearis), haddock (Melanogrammus aeglefinus), hake (Urophycis), pollock (Pollachius), and others." []
synonym: "white fish" EXACT []
xref: https://fdc.nal.usda.gov/fdc-app.html#/food-details/173711/nutrients
is_a: FOODON:03411222 ! fish species

[Term]
id: FOODON:00003282
name: hen
def: "A sexually mature female bird." []
is_a: FOODON:00004298 ! poultry
is_a: UBERON:0003100 ! female organism
is_a: UBERON:0007023 ! adult organism
intersection_of: FOODON:00004298 ! poultry
intersection_of: UBERON:0003100 ! female organism
intersection_of: UBERON:0007023 ! adult organism

[Term]
id: FOODON:00003288
name: multi-component meat product
is_a: FOODON:00002501 ! multi-component food

[Term]
id: FOODON:00003297
name: turkey sausage
def: "A sausage made from turkey meat" []
is_a: FOODON:00001286 ! turkey meat food product
is_a: FOODON:00001605 ! animal product sausage

[Term]
id: FOODON:00003318
name: echinoderm food product
is_a: FOODON:00001293 ! shellfish food product
is_a: FOODON:00005703 ! echinoderm material
intersection_of: FOODON:00001293 ! shellfish food product
intersection_of: RO:0001000 FOODON:03412115 ! derives from echinoderm
relationship: RO:0001000 FOODON:03412115 ! derives from echinoderm

[Term]
id: FOODON:00003324
name: citrus fruit
def: "A hesperidium fruit of a citrus plant (Citrus)." []
is_a: FOODON:00001151 ! citrus fruit food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:2706 ! in taxon Citrus

[Term]
id: FOODON:00003341
name: brassica food product
def: "A genus of plants in the mustard family (Brassicaceae). The members of the genus are informally known as cruciferous vegetables, cabbages, or mustard plants." []
is_a: FOODON:00001169 ! cruciferous food product
is_a: FOODON:00001261 ! vegetable food product
relationship: RO:0001000 NCBITaxon:3705 ! derives from Brassica
relationship: RO:0002162 NCBITaxon:3705 ! in taxon Brassica

[Term]
id: FOODON:00003349
name: white onion (raw)
def: "A cultivar of dry onion, that has a pure white papery skin and a sweet, mild white flesh." []
is_a: FOODON:00003518 ! white onion
is_a: FOODON:03301704 ! onion (raw)
intersection_of: FOODON:00003518 ! white onion
intersection_of: FOODON:03301704 ! onion (raw)

[Term]
id: FOODON:00003395
name: multi-component wheat food product
is_a: FOODON:03316579 ! multi-component plant food product
relationship: RO:0001000 FOODON:03411312 ! derives from wheat plant

[Term]
id: FOODON:00003405
name: broccoli floret
def: "A raceme inflorescence of a broccoli plant(Brassica oleracea var. italica)." []
synonym: "broccoli" EXACT []
is_a: FOODON:00001666 ! broccoli food product
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:36774 ! in taxon Brassica oleracea var. italica

[Term]
id: FOODON:00003406
name: cabbage head
def: "A rosette of a cabbage plant (Brassica oleracea var. capitata)." []
synonym: "cabbage" EXACT []
is_a: FOODON:00001677 ! cabbage head food product
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3716 ! in taxon Brassica oleracea var. capitata

[Term]
id: FOODON:00003408
name: carrot root
def: "A primary root of a carrot plant (Daucus carota)." []
synonym: "carrot" EXACT []
is_a: FOODON:00001687 ! carrot food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:4039 ! in taxon Daucus carota

[Term]
id: FOODON:00003410
name: cauliflower floret
def: "A raceme inflorescence of a cauliflower plant (Brassica oleracea var. botrytis)." []
synonym: "cauliflower" EXACT []
is_a: FOODON:00001703 ! cauliflower food product
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3715 ! in taxon Brassica oleracea var. botrytis

[Term]
id: FOODON:00003417
name: grape
def: "A berry fruit of a grape plant." []
synonym: "de-stemmed grape" EXACT []
is_a: FOODON:00001170 ! grape berry food product
is_a: FOODON:00003521 ! berry
relationship: RO:0002162 FOODON:03411329 ! in taxon grape cultivar

[Term]
id: FOODON:00003427
name: maize kernel
def: "A caryopsis fruit of a maize plant  (Zea mays subsp. mays)." []
synonym: "corn kernel" EXACT []
is_a: FOODON:00001142 ! maize (corn) food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:381124 ! in taxon Zea mays subsp. mays

[Term]
id: FOODON:00003433
name: raspberry
def: "An aggregate fruit of a raspberry plant." []
is_a: FOODON:00002190 ! raspberry food product
is_a: FOODON:00003477 ! drupelet berry
is_a: FOODON:00003521 ! berry
intersection_of: FOODON:00003592 ! aggregate fruit
intersection_of: RO:0002162 FOODON:03411494 ! in taxon raspberry plant
relationship: RO:0002162 FOODON:03411494 ! in taxon raspberry plant

[Term]
id: FOODON:00003434
name: whole grain rice kernel
def: "A caryopsis fruit of a rice plant (Oryza sativa)." []
is_a: FOODON:03301641 ! rice kernel food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:4530 ! in taxon Oryza sativa

[Term]
id: FOODON:00003436
name: brown rice kernel
is_a: FOODON:00003434 ! whole grain rice kernel

[Term]
id: FOODON:00003443
name: strawberry
def: "An aggregate fruit of strawberry plant  (Fragaria x ananassa)." []
is_a: FOODON:00002282 ! strawberry food product
is_a: FOODON:00003592 ! aggregate fruit
intersection_of: FOODON:00003592 ! aggregate fruit
intersection_of: RO:0002162 NCBITaxon:3747 ! in taxon Fragaria x ananassa
relationship: RO:0002162 NCBITaxon:3747 ! in taxon Fragaria x ananassa

[Term]
id: FOODON:00003445
name: sweet potato
def: "A tuberous root tuber of a sweet potato plant (Ipomoea batatas)." []
is_a: FOODON:00002297 ! sweet potato food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:4120 ! in taxon Ipomoea batatas

[Term]
id: FOODON:00003448
name: yam
def: "A shoot axis tuber of a yam plant (Dioscorea)." []
is_a: FOODON:00002368 ! yam food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:4672 ! in taxon Dioscorea

[Term]
id: FOODON:00003473
name: salmon
is_a: FOODON:00002220 ! salmon food product
relationship: RO:0001000 NCBITaxon:8015 ! derives from Salmonidae

[Term]
id: FOODON:00003476
name: apricot
def: "A drupe fruit of an apricot tree (Prunus armeniaca)." []
is_a: FOODON:00001615 ! apricot food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:36596 ! in taxon Prunus armeniaca

[Term]
id: FOODON:00003477
name: drupelet berry
synonym: "berry" EXACT []
is_a: FOODON:00003026 ! drupelet berry food product
is_a: FOODON:00003592 ! aggregate fruit

[Term]
id: FOODON:00003483
name: plum
def: "A drupe fruit of a plum plant." []
is_a: FOODON:00002161 ! plum fruit food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 FOODON:03411206 ! in taxon plum plant

[Term]
id: FOODON:00003486
name: pumpkin
def: "An orange-yellow pepo fruit of a pumpkin plant." []
is_a: FOODON:00002180 ! pumpkin food product
is_a: FOODON:00003946 ! winter squash
relationship: RO:0002162 FOODON:03411456 ! in taxon pumpkin plant

[Term]
id: FOODON:00003495
name: spinach leaf
def: "A rosette leaf of a spinach plant (Spinacia oleracea)" []
is_a: FOODON:00002269 ! spinach food product
is_a: FOODON:03420144 ! plant above surface, excluding fruit and seed
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3562 ! in taxon Spinacia oleracea

[Term]
id: FOODON:00003500
name: collard leaf
def: "A rosette leaf of a collard plant (Brassica oleracea var. viridis)" []
is_a: FOODON:00001755 ! collard food product
is_a: FOODON:03420144 ! plant above surface, excluding fruit and seed
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3713 ! in taxon Brassica oleracea var. viridis

[Term]
id: FOODON:00003501
name: kale leaf
def: "A rosette leaf of a kale plant" []
is_a: FOODON:00001981 ! kale food product
is_a: FOODON:00003650 ! vegetable leaf
relationship: RO:0002162 FOODON:03411281 ! in taxon kale plant

[Term]
id: FOODON:00003515
name: red onion (raw)
is_a: FOODON:00003516 ! red onion
is_a: FOODON:03301704 ! onion (raw)
intersection_of: FOODON:00003516 ! red onion
intersection_of: FOODON:03301704 ! onion (raw)

[Term]
id: FOODON:00003516
name: red onion
def: "A bulb of a red onion plant cultivar" []
is_a: FOODON:03316347 ! onion

[Term]
id: FOODON:00003517
name: yellow onion
def: "A bulb of a yellow onion plant cultivar" []
is_a: FOODON:03316347 ! onion

[Term]
id: FOODON:00003518
name: white onion
def: "A bulb of a white onion plant cultivar" []
is_a: FOODON:03316347 ! onion

[Term]
id: FOODON:00003520
name: pepper
def: "A berry fruit of a pepper plant (Capsicum)" []
is_a: FOODON:00002111 ! pepper vegetable food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:4071 ! in taxon Capsicum

[Term]
id: FOODON:00003521
name: berry
def: "A juicy, rounded, brightly colored fruit without a stone or pit, though pips or seeds may be present." []
synonym: "common berry" EXACT []
is_a: FOODON:03315614 ! berry product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 FOODON:03411231 ! in taxon berry plant

[Term]
id: FOODON:00003523
name: almond
def: "A drupe fruit of an almond plant (Prunus dulcis)." []
is_a: FOODON:00001587 ! almond food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3755 ! in taxon Prunus dulcis

[Term]
id: FOODON:00003530
name: chard leaf
def: "A rosette leaf of a chard plant (Beta vulgaris subsp. vulgaris)." []
is_a: FOODON:00002498 ! chard food product
is_a: FOODON:00003633 ! beet leaf

[Term]
id: FOODON:00003539
name: squash
def: "A pepo fruit varietal of a squash plant (Cucurbita)." []
is_a: FOODON:00002271 ! squash food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3660 ! in taxon Cucurbita

[Term]
id: FOODON:00003541
name: blueberry
def: "A berry fruit of a blueberry plant." []
is_a: FOODON:00001656 ! blueberry food product
is_a: FOODON:00003521 ! berry
relationship: RO:0002162 FOODON:03411491 ! in taxon blueberry plant

[Term]
id: FOODON:00003546
name: bell pepper
def: "A berry fruit in the Grossum cultivar group of a bell pepper plant." []
synonym: "bell pepper" EXACT []
synonym: "capsicum" EXACT []
synonym: "pepper" EXACT []
synonym: "sweet pepper" EXACT []
is_a: FOODON:00003013 ! bell pepper food product
is_a: FOODON:03000128 ! serrano pepper
relationship: RO:0002162 FOODON:03412628 ! in taxon bell pepper plant

[Term]
id: FOODON:00003554
name: grapefruit
def: "A hesperidium fruit of a grapefruit tree (Citrus x paradisi)." []
is_a: FOODON:00001929 ! grapefruit food product
is_a: FOODON:00003324 ! citrus fruit
relationship: RO:0002162 NCBITaxon:37656 ! in taxon Citrus x paradisi

[Term]
id: FOODON:00003575
name: Williams pear
def: "A pome fruit of a williams bon chrétien pear plant, cultivar of a common pear." []
synonym: "Bartlett pear" EXACT []
synonym: "Williams' Bon Chrétien pear" EXACT []
is_a: FOODON:00003576 ! common pear
relationship: RO:0002162 FOODON:00002842 ! in taxon Williams bon chrétien pear plant

[Term]
id: FOODON:00003576
name: common pear
def: "A pome fruit of a common pear plant (Pyrus communis)" []
synonym: "european pear" EXACT []
is_a: FOODON:00003041 ! pear
relationship: RO:0002162 NCBITaxon:23211 ! in taxon Pyrus communis

[Term]
id: FOODON:00003577
name: cantaloupe
def: "A pepo fruit of a cantaloupe plant (Cucumis melo var. cantalupo)." []
is_a: FOODON:00001288 ! cantaloupe fruit food product
is_a: FOODON:00003596 ! muskmelon
relationship: RO:0002162 NCBITaxon:3658 ! in taxon Cucumis melo var. cantalupo

[Term]
id: FOODON:00003592
name: aggregate fruit
def: "A fruit that develops from the merger of several ovaries that were separated in a single flower." []
synonym: "etaerio" EXACT []
is_a: BFO:0000040 ! material entity
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae

[Term]
id: FOODON:00003596
name: muskmelon
def: "A pepo fruit of a muskmelon plant (Cucumis melo )" []
is_a: FOODON:00001153 ! muskmelon (Cucumis melo) fruit food product
is_a: FOODON:00003597 ! melon
relationship: RO:0002162 NCBITaxon:3656 ! in taxon Cucumis melo

[Term]
id: FOODON:00003597
name: melon
def: "A pepo fruit of a melon plant." []
is_a: FOODON:00001152 ! melon fruit food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3650 ! in taxon Cucurbitaceae

[Term]
id: FOODON:00003600
name: avocado
def: "A berry fruit of an avocado plant (Persea americana)" []
is_a: FOODON:00001625 ! avocado food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3435 ! in taxon Persea americana

[Term]
id: FOODON:00003615
name: cashew nut
def: "A nut fruit from a cashew tree (Anacardium occidentale)" []
is_a: FOODON:00001688 ! cashew nut food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:171929 ! in taxon Anacardium occidentale

[Term]
id: FOODON:00003618
name: eggplant
def: "A berry fruit of an eggplant (Solanum virginianum)" []
synonym: "aubergine" EXACT []
synonym: "brinjal" EXACT []
synonym: "egg plant" EXACT []
is_a: FOODON:00001830 ! eggplant food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:223891 ! in taxon Solanum virginianum

[Term]
id: FOODON:00003631
name: swiss chard leaf
def: "A rosette leaf of a swiss chard plant (Beta vulgaris subsp. vulgaris)." []
is_a: FOODON:00003530 ! chard leaf

[Term]
id: FOODON:00003633
name: beet leaf
def: "A leaf of a beet plant." []
synonym: "beetroot leaf" EXACT []
is_a: FOODON:00001638 ! beet food product
is_a: FOODON:03420144 ! plant above surface, excluding fruit and seed
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:161934 ! in taxon Beta vulgaris

[Term]
id: FOODON:00003650
name: vegetable leaf
def: "A leaf of a vegetable-producing plant." []
is_a: FOODON:03315308 ! vegetable (whole or pieces)
is_a: FOODON:03420144 ! plant above surface, excluding fruit and seed
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 FOODON:03411579 ! in taxon vegetable-producing plant

[Term]
id: FOODON:00003673
name: watermelon
def: "A pepo fruit of a watermelon plant (Citrullus lanatus )." []
is_a: FOODON:00002343 ! watermelon food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:3654 ! in taxon Citrullus lanatus

[Term]
id: FOODON:00003718
name: ginseng root
def: "A root of a ginseng plant" []
is_a: FOODON:00001905 ! ginseng plant food product
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:4053 ! in taxon Panax

[Term]
id: FOODON:00003738
name: vanilla bean
def: "A seed of a vanilla bean plant." []
is_a: FOODON:00002328 ! vanilla bean food product
is_a: FOODON:00002753 ! bean
is_a: FOODON:03301467 ! bean (whole or pieces)
relationship: RO:0002162 FOODON:03411355 ! in taxon vanilla plant

[Term]
id: FOODON:00003744
name: chili pepper
def: "A berry fruit of a chili pepper plant." []
synonym: "chile" EXACT []
synonym: "chile pepper" EXACT []
synonym: "chili" EXACT []
synonym: "chili pod" EXACT []
synonym: "chilli" EXACT []
synonym: "chilli pepper" EXACT []
synonym: "chīlli" EXACT []
synonym: "green chili" EXACT []
synonym: "green chilli pepper" EXACT []
synonym: "red chili pepper" EXACT []
xref: https://bioregistry.io/reference/siren\:F15873
is_a: FOODON:00001956 ! hot pepper food product
is_a: FOODON:00003520 ! pepper

[Term]
id: FOODON:00003774
name: oat bran
def: "Seed bran of an oat plant (Avena sativa)" []
is_a: FOODON:00001189 ! oat food product
is_a: FOODON:03420288 ! seed bran
intersection_of: FOODON:03420288 ! seed bran
intersection_of: RO:0002162 NCBITaxon:4498 ! in taxon Avena sativa
relationship: RO:0002162 NCBITaxon:4498 ! in taxon Avena sativa

[Term]
id: FOODON:00003778
name: red grape
def: "A berry fruit of a red grape cultivar." []
is_a: FOODON:00003417 ! grape
relationship: RO:0002162 FOODON:00004063 ! in taxon red grape cultivar

[Term]
id: FOODON:00003787
name: white rice
synonym: "milled white rice" EXACT []
synonym: "white rice" EXACT []
is_a: FOODON:03420102 ! germinated or sprouted seed
is_a: FOODON:03420208 ! seed, skin removed, germ removed (endosperm)

[Term]
id: FOODON:00003816
name: vegetable
def: "An anatomical part of a plant that is consumed by humans or other animals as food." []
is_a: FOODON:03315308 ! vegetable (whole or pieces)
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae

[Term]
id: FOODON:00003837
name: soybean sprout
def: "A germinated or sprouted seed of a soyabean plant (Glycine max)." []
synonym: "soy sprout" EXACT []
synonym: "soyabean sprout" EXACT []
is_a: FOODON:00002576 ! bean sprout
is_a: FOODON:03420102 ! germinated or sprouted seed
intersection_of: FOODON:00002576 ! bean sprout
intersection_of: RO:0002162 NCBITaxon:3847 ! in taxon Glycine max
relationship: RO:0002162 NCBITaxon:3847 ! in taxon Glycine max

[Term]
id: FOODON:00003845
name: pork ear
def: "A whole animal ear that is obtained from a pork." []
synonym: "pig ear" EXACT []
synonym: "pig's ear" EXACT []
synonym: "porcine pig ear" EXACT []
is_a: FOODON:00001038 ! pork meat food product
is_a: FOODON:02010056 ! animal ear
is_a: FOODON:02021664 ! pork organ
intersection_of: FOODON:02010056 ! animal ear
intersection_of: RO:0002162 NCBITaxon:9825 ! in taxon Sus scrofa domesticus

[Term]
id: FOODON:00003866
name: cashew milk
def: "Cashew milk is a manufactured, nondairy beverage made from water-based cashew extract for flavouring and aroma." []
synonym: "cashew mylk" EXACT []
is_a: FOODON:00001688 ! cashew nut food product

[Term]
id: FOODON:00003905
name: Silybum marianum seed
def: "A seed of a milk thistle plant (Silybum marianum)." []
synonym: "milk thistle seed" EXACT []
is_a: BFO:0000040 ! material entity
is_a: UBERON:0001062 ! anatomical entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:92921 ! in taxon Silybum marianum

[Term]
id: FOODON:00003906
name: Hypericum perforatum flower
def: "A flower bud of a St. John's wort plant (Hypericum perforatum)." []
synonym: "St. John's wort flower" EXACT []
is_a: BFO:0000040 ! material entity
relationship: RO:0002160 NCBITaxon:33090 ! only in taxon Viridiplantae
relationship: RO:0002162 NCBITaxon:65561 ! in taxon Hypericum perforatum

[Term]
id: FOODON:00003908
name: spinach (cooked)
def: "The spinach material output of a cooking process." []
is_a: FOODON:00001181 ! food (cooked)
is_a: FOODON:00002269 ! spinach food product
intersection_of: FOODON:00001181 ! food (cooked)
intersection_of: FOODON:00002269 ! spinach food product

[Term]
id: FOODON:00003923
name: whole grain bread
def: "A bread food product made substantially from whole grains." []
is_a: FOODON:00001183 ! bread food product
intersection_of: FOODON:00001183 ! bread food product
intersection_of: FOODON:00001563 FOODON:00003950 ! has defining ingredient whole grain
relationship: FOODON:00001563 FOODON:00003950 ! has defining ingredient whole grain

[Term]
id: FOODON:00003938
name: whole oat bread
def: "A whole grain bread that contains whole oats (Avena sativa)." []
is_a: FOODON:00003923 ! whole grain bread
intersection_of: FOODON:00003923 ! whole grain bread
intersection_of: FOODON:00001563 FOODON:03315188 ! has defining ingredient oat kernel
relationship: FOODON:00001563 FOODON:03315188 ! has defining ingredient oat kernel

[Term]
id: FOODON:00003939
name: diet soft drink (caffeinated)
def: "A soft drink that is sweetened by a nonnutritive sweetener and contains caffeine." []
synonym: "caffeinated diet pop" EXACT []
synonym: "caffeinated diet soda" EXACT []
is_a: FOODON:00003940 ! soft drink (caffeinated)
is_a: FOODON:03310547 ! soft drink (dietetic)
intersection_of: FOODON:03310547 ! soft drink (dietetic)
intersection_of: BFO:0000051 CHEBI:27732 ! has part caffeine
intersection_of: FOODON:00002420 CHEBI:27732 ! has ingredient caffeine

[Term]
id: FOODON:00003940
name: soft drink (caffeinated)
def: "A soft drink that contains caffeine." []
synonym: "caffeinated pop" EXACT []
synonym: "caffeinated soda" EXACT []
is_a: FOODON:03310815 ! soft drink
intersection_of: FOODON:03310815 ! soft drink
intersection_of: BFO:0000051 CHEBI:27732 ! has part caffeine
intersection_of: FOODON:00002420 CHEBI:27732 ! has ingredient caffeine
relationship: BFO:0000051 CHEBI:27732 ! has part caffeine
relationship: FOODON:00002420 CHEBI:27732 ! has ingredient caffeine

[Term]
id: FOODON:00003941
name: tea (liquid, decafeinated)
is_a: FOODON:00001245 ! tea beverage (liquid)
intersection_of: FOODON:00001245 ! tea beverage (liquid)
intersection_of: FOODON:00001563 FOODON:03312068 ! has defining ingredient tea (decaffeinated)
relationship: FOODON:00001563 FOODON:03312068 ! has defining ingredient tea (decaffeinated)

[Term]
id: FOODON:00003942
name: tea (liquid, caffeinated)
is_a: FOODON:00001245 ! tea beverage (liquid)
intersection_of: FOODON:00001245 ! tea beverage (liquid)
intersection_of: BFO:0000051 CHEBI:27732 ! has part caffeine
intersection_of: FOODON:00002420 CHEBI:27732 ! has ingredient caffeine
rela