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"http://purl.obolibrary.org/obo/FBdv_00007011", "propertyId": "http://purl.obolibrary.org/obo/FBdv_00018001" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/FBdv_00007023", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0000279" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/FBdv_00007011", "propertyId": "http://purl.obolibrary.org/obo/FBdv_00018001" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/GO_0000087", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0000279" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/GO_0000278", "propertyId": "http://purl.obolibrary.org/obo/RO_0002092" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/GO_0000278", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0007049" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/GO_0140014", "propertyId": "http://purl.obolibrary.org/obo/BFO_0000051" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/GO_0022402", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0009987" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/GO_0007049", "propertyId": "http://purl.obolibrary.org/obo/BFO_0000050" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/GO_0051329", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0051325" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/GO_0000278", "propertyId": "http://purl.obolibrary.org/obo/RO_0002092" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/GO_0098763", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0022403" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/GO_0000278", "propertyId": "http://purl.obolibrary.org/obo/RO_0002092" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/GO_0140014", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0000280" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/GO_0000278", "propertyId": "http://purl.obolibrary.org/obo/BFO_0000050" } ] }, { "definedClassId": "http://purl.obolibrary.org/obo/GO_1903047", "genusIds": [ "http://purl.obolibrary.org/obo/GO_0009987" ], "restrictions": [ { "fillerId": "http://purl.obolibrary.org/obo/GO_0000278", "propertyId": "http://purl.obolibrary.org/obo/BFO_0000050" } ] } ], "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000700", "val": "http://purl.obolibrary.org/obo/FBdv_00000000" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000700", "val": "http://purl.obolibrary.org/obo/FBdv_00005259" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000700", "val": "http://purl.obolibrary.org/obo/FBdv_00007013" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000700", "val": "http://purl.obolibrary.org/obo/FBdv_00007024" }, { "pred": "http://purl.org/dc/elements/1.1/creator", "val": "http://orcid.org/0000-0002-1373-1705" }, { "pred": "http://purl.org/dc/elements/1.1/creator", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/elements/1.1/creator", "val": "https://orcid.org/0000-0001-5948-3092" }, { "pred": "http://purl.org/dc/elements/1.1/creator", "val": "https://orcid.org/0000-0002-0027-0858" }, { "pred": "http://purl.org/dc/elements/1.1/description", "val": "An ontology of Drosophila melanogaster developmental stages." }, { "pred": "http://purl.org/dc/elements/1.1/title", "val": "Drosophila Developmental Ontology" }, { "pred": "http://purl.org/dc/terms/license", "val": "https://creativecommons.org/licenses/by/4.0/" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#NamespaceIdRule", "val": "* FBdv:$sequence(8,7000,10000)$" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#date", "val": "08:02:2023 13:47" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#default-namespace", "val": "FlyBase_development_CV" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion", "val": "1.2" }, { "pred": "http://www.w3.org/2002/07/owl#versionInfo", "val": "2023-02-08" } ], "version": "http://purl.obolibrary.org/obo/fbdv/releases/2023-02-08/fbdv.json" }, "nodes": [ { "id": "http://purl.obolibrary.org/obo/BFO_0000002", "lbl": "continuant", "meta": { "definition": { "val": "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000003", "lbl": "occurrent", "meta": { "definition": { "val": "An entity that has temporal parts and that happens, unfolds or develops through time." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000004", "lbl": "independent continuant", "meta": { "definition": { "val": "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000015", "lbl": "process", "meta": { "definition": { "val": "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000017", "lbl": "realizable entity", "meta": { "definition": { "val": "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000020", "lbl": "specifically dependent continuant", "meta": { "definition": { "val": "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000023", "lbl": "role", "meta": { "definition": { "val": "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000040", "lbl": "material entity", "meta": { "definition": { "val": "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000050", "lbl": "part of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "is part of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "my brain is part of my body (continuant parthood, two material entities)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this day is part of this year (occurrent parthood)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "part_of" }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" }, { "pred": "http://purl.obolibrary.org/obo/RO_0040042", "val": "http://purl.obolibrary.org/obo/BFO_0000002" }, { "pred": "http://purl.obolibrary.org/obo/RO_0040042", "val": "http://purl.obolibrary.org/obo/BFO_0000003" }, { "pred": "http://purl.obolibrary.org/obo/RO_0040042", "val": "http://purl.obolibrary.org/obo/BFO_0000004" }, { "pred": "http://purl.obolibrary.org/obo/RO_0040042", "val": "http://purl.obolibrary.org/obo/BFO_0000017" }, { "pred": "http://purl.obolibrary.org/obo/RO_0040042", "val": "http://purl.obolibrary.org/obo/BFO_0000019" }, { "pred": "http://purl.obolibrary.org/obo/RO_0040042", "val": "http://purl.obolibrary.org/obo/BFO_0000020" }, { "pred": "http://purl.obolibrary.org/obo/RO_0040042", "val": "http://purl.obolibrary.org/obo/BFO_0000031" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "external" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "part_of" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://ontologydesignpatterns.org/wiki/Submissions:PartOf" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://www.obofoundry.org/ro/#OBO_REL:part_of" } ], "definition": { "val": "a core relation that holds between a part and its whole" }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_gp2term", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ], "xrefs": [ { "val": "BFO:0000050" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000051", "lbl": "has part", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "has part" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "my body has part my brain (continuant parthood, two material entities)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this year has part this day (occurrent parthood)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has_part" }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "external" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "has_part" } ], "definition": { "val": "a core relation that holds between a whole and its part" }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ], "xrefs": [ { "val": "BFO:0000051" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000062", "lbl": "preceded by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "preceded by" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "is preceded by" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "preceded_by" }, { "pred": "http://purl.org/dc/elements/1.1/source", "val": "http://www.obofoundry.org/ro/#OBO_REL:preceded_by" } ], "definition": { "val": "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." }, "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/BFO_0000063", "lbl": "precedes", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "precedes" } ], "definition": { "val": "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." }, "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/CARO_0000000", "lbl": "anatomical entity", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000412", "val": "http://purl.obolibrary.org/obo/caro.owl" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00000000", "lbl": "Drosophila life", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "FBdv_root:00000000" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "The life of an individual of the species Drosophila melanogaster, from fertilization to death.", "xrefs": [ "FBC:DOS" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "Drosophila life cycle" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00000054", "lbl": "cleavage stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 25." ], "definition": { "val": "A collective term for stages 1-4.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00004450", "lbl": "late extended germ band stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 300." ], "definition": { "val": "A collective term for stages 11 and 12.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00004886", "lbl": "oogenesis", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10000." ], "synonyms": [ { "pred": "hasExactSynonym", "val": "oogenesis stage" } ], "xrefs": [ { "val": "GO:0048477" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005259", "lbl": "developmental stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2009-10-01T05:56:56Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "FBdv:00007010" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "A temporal subdivision of a developmental process.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005261", "lbl": "oogenesis stage S1", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10010." ], "definition": { "val": "Earliest stage of ovarian cyst development - lasts while the 16 cell cyst is within the germarium (region 3).", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005262", "lbl": "oogenesis stage S2", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10020." ], "definition": { "val": "Oogenesis stage that begins when the cyst leaves the germarium (from this point the cyst is referred to as an egg chamber). During this stage, polyploidation of the nurse cells begins, they reach a ploidy of 8C, and follicle cells start to divide.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005263", "lbl": "oogenesis stage S3", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10030." ], "definition": { "val": "Oogenesis stage that begins when the oocyte chromosomes condense into a karyosome attached to a distinctive spherical structure known as an endobody. The oocyte nucleolus disappears completely. During this stage, nurse cell ploidy reaches 16C.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005264", "lbl": "oogenesis stage S4", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10040." ], "definition": { "val": "Oogenesis stage that begins when the nurse cells chromosomes become bulbous. Nurse cell chromosomes during this stage are polytene and reach a ploidy of 32C. The egg chamber is oval shaped.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005265", "lbl": "oogenesis stage S5", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10050." ], "definition": { "val": "Oogenesis stage that begins when nurse cell chromosomes are no longer bulbous - the association between homologs weakens so that these chromosomes no longer have a polytene structure. During this stage, posterior nurse cell nuclei have a higher ploidy (64C) than anterior ones.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005266", "lbl": "oogenesis stage S6", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10060." ], "definition": { "val": "Oogenesis stage during which follicle cell division ceases.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005267", "lbl": "oogenesis stage S7", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10070." ], "definition": { "val": "Oogenesis stage during which polyploidation and enlargement of follicle cells begins. Nurse cell ploidy ranges from 256C (anterior) to 512C (posterior) and the egg chamber gains an elongated shape.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005268", "lbl": "oogenesis stage S8", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10080." ], "definition": { "val": "Oogenesis stage which begins when yolk first appears in the oocyte. Follicle cell migration over the oocyte begins during this stage (although mostly occurs during stage 9).", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005269", "lbl": "oogenesis stage S9", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10090." ], "definition": { "val": "Oogenesis stage that begins when the border cells begin to migrate. During this stage: the oocyte is about 1/3 the length of the egg chamber with its nucleus located antero-dorsally; follicle cell migration results in an anterior to posterior gradient of follicle cell thickness with posterior cells being thicker (-> columnar) and posterior cells thinner ( -> squamous); border cell migration begins and ends; secretion of vitelline membrane begins.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005270", "lbl": "oogenesis stage S10", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10100." ], "definition": { "val": "Oogenesis stage that begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends with the beginning of nurse cell dumping.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005271", "lbl": "oogenesis stage S10A", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10110." ], "definition": { "val": "Oogenesis stage which begins when all the oocyte associated follicular epithelium is columnar and all of the nurse cell associated follicular epithelium is completely squamous and ends when centripetal follicle migration begins. During this stage, the migrating border cells reach the oocyte. The oocyte is about 50% egg chamber length.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005272", "lbl": "oogenesis stage S10B", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10120." ], "definition": { "val": "Oogenesis stage that begins when the centripetal follicle cells begin to migrate. As a result, the vitelline membrane extends into the opercular region. This stage ends when nurse cell dumping begins.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005273", "lbl": "oogenesis stage S11", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10130." ], "definition": { "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins. The dorsal appendages begin to form during this stage. This stage ends when dying nurse cells form an anterior cap to the oocyte.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005274", "lbl": "oogenesis stage S12", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10160." ], "definition": { "val": "Oogenesis stage that begins when dying nurse cells form an anterior cap to the oocyte. Shortly after this, nurse cell dumping and growth of the oocyte are complete. Elongation of the dorsal appendages and formation of the innermost chorionic layer and endochorion begins during this stage.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0034074", "FlyBase:FBrf0043885", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005275", "lbl": "oogenesis stage S12A", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10170." ], "definition": { "val": "Innermost chorionic layer and endochorion begin to form in the anterior of the follicle.", "xrefs": [ "FlyBase:FBrf0043885" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005276", "lbl": "oogenesis stage S12B", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10180." ], "definition": { "val": "Secretion of innermost chorionic layer and endochorion begins in the main follicle cells.", "xrefs": [ "FlyBase:FBrf0043885" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005277", "lbl": "oogenesis stage S12C", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10190." ], "definition": { "val": "Formation of specialized endochorion structures in the anterior of the follicle: branches in the developing dorsal appendages; compact endochorion lacking the pillars seen in the rest of the follicle.", "xrefs": [ "FlyBase:FBrf0021038" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005278", "lbl": "oogenesis stage S13", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10200." ], "definition": { "val": "Oogenesis stage that begins when the micropyle begins to form. At the beginning of this stage, about 12-15 nurse cell nuclei remain at the anterior of the oocyte. By the end of this stage, none of these nuclei remain. Oocyte meiosis up to arrest at full metaphase I occurs during this stage.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0029744", "FlyBase:FBrf0034074", "FlyBase:FBrf0064777" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005279", "lbl": "oogenesis stage S13A", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10210. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ], "definition": { "val": "Oogenesis stage during which 12-15 nurse cell nuclei remain at the anterior of the oocyte. At this stage, the oocyte nucleus has reached its maximum volume and its chromosomes are compressed into a 5-7 micrometer karyosome.", "xrefs": [ "FlyBase:FBrf0029744" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005280", "lbl": "oogenesis stage S13B", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10220. An alternative division of stage 13 into two sub-stages, A and B, has been defined on the basis of chorion development (see FBrf0043885). This ontology uses an alternative subdivision based on nurse cell nucleus number and oocyte meiosis, as the former at least, is easier to score than chorion ultrastructure." ], "definition": { "val": "Oogenesis stage during which 9-11 nurse cell nuclei remain at the anterior of the oocyte. During this stage, the nuclear membrane of the oocyte nucleus disappears, indicating the start of meiotic pro-metaphase.", "xrefs": [ "FlyBase:FBrf0029744" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005281", "lbl": "oogenesis stage S13C", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10230." ], "definition": { "val": "Oogenesis stage during which only 7-8 nurse cell nuclei remain at the anterior of the oocyte. At the beginning of this stage, oocyte chromosome bivalents separate from each other - indicating mid-prometaphase of oocyte meiosis.", "xrefs": [ "FlyBase:FBrf0029744" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005282", "lbl": "oogenesis stage S13D", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10240." ], "definition": { "val": "Oogenesis stage during which only 5-6 nurse cell nuclei remain at the anterior of the oocyte. The oocyte nucleus is in late prometaphase:the bivalents arrange themselves in on the equatorial plane of the spindle; homologous centromeres are pulled towards the poles.", "xrefs": [ "FlyBase:FBrf0029744" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005283", "lbl": "oogenesis stage S14", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10260." ], "definition": { "val": "The last stage of oogenesis. This stage begins when no nurse cell nuclei remain at the anterior of the egg (chamber). Exochorion formation and secretion occurs during this stage. The dorsal appendages complete their elongation and the follicle cells die.", "xrefs": [ "FlyBase:FBrf0043885" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005284", "lbl": "oogenesis stage S14A", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10270." ], "definition": { "val": "Secretion and formation of the outer endochorionic network by throughout the follicle. Crystallization of the innermost chorionic layer of the main body follicle cells.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0043885" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005285", "lbl": "oogenesis stage S14B", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10280." ], "definition": { "val": "Secretion of the exochorion begins and ends.", "xrefs": [ "FlyBase:FBrf0021038", "FlyBase:FBrf0043885" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005286", "lbl": "egg stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10290." ], "definition": { "val": "The stage of the Drosophila life-cycle from maturation of an egg to the end of fertilization. At the beginning of this stage, the nucleus is arrested in meiotic metaphase I. The completion of meiosis and the start of protein synthesis are triggered by ovulation. If the female has already mated, fertilization begins during meiosis.", "xrefs": [ "FlyBase:FBrf0064779" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005287", "lbl": "unfertilized egg stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10300." ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005288", "lbl": "fertilized egg stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10." ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005289", "lbl": "embryonic stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 20." ], "definition": { "val": "The stage of the Drosophila life-cycle from fertilization to hatching.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005290", "lbl": "pre-blastoderm stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 30." ], "definition": { "val": "Embryonic stage 1-3.", "xrefs": [ "FBC:DOS" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pre-blastoderm" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005291", "lbl": "embryonic stage 1", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 40." ], "definition": { "val": "The embryonic stage that lasts from the end of fertilization to the end of the second nuclear division. Duration at 25 degrees C: approximately 25 minutes (0-25 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0064779", "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005292", "lbl": "embryonic cycle 1", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 50." ], "definition": { "val": "The first mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005293", "lbl": "embryonic stage 2", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 70." ], "definition": { "val": "Nuclear divisions 3-8. The egg cytoplasm contracts producing a clear separation from the vitelline membrane and empty spaces at the anterior and posterior. The cleavage nuclei migrate towards the periphery. Duration at 25 degrees C approximately 40 minutes (25-65 minutes AEL).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005294", "lbl": "embryonic cycle 2", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 60." ], "definition": { "val": "The second mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005295", "lbl": "embryonic cycle 3", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 80." ], "definition": { "val": "The third mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005296", "lbl": "embryonic cycle 4", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 90." ], "definition": { "val": "The fourth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005297", "lbl": "embryonic cycle 5", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 100." ], "definition": { "val": "The fifth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005298", "lbl": "embryonic cycle 6", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 110." ], "definition": { "val": "The sixth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005299", "lbl": "embryonic cycle 7", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 120." ], "definition": { "val": "The seventh mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005300", "lbl": "embryonic cycle 8", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 130." ], "definition": { "val": "The eighth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005301", "lbl": "embryonic stage 3", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 140." ], "definition": { "val": "Nuclear division 9. The cleavage nuclei complete their migration to the periphery. Polar buds form at the posterior pole and divide once. Duration at 25 degrees C: approximately 15 minutes (65-80 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005302", "lbl": "embryonic cycle 9", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 150." ], "definition": { "val": "The ninth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005303", "lbl": "embryonic cycle 10", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 180." ], "definition": { "val": "The tenth mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005304", "lbl": "blastoderm stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 160." ], "definition": { "val": "Embryonic stages 4 and 5.", "xrefs": [ "FBC:DOS" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "blastoderm" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005305", "lbl": "obsolete syncytial blastoderm stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "deprecated": true }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005306", "lbl": "embryonic stage 4", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 170." ], "definition": { "val": "Nuclear division 10-13. Polar buds divide twice and become tightly grouped at the posterior pole by the end of this stage. Nuclei visible at the rim of the embryo. Stage 4 ends with the beginning of cellularization. Duration at 25 degrees C: approximately 50 minutes (80-130 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "syncytial blastoderm" }, { "pred": "hasExactSynonym", "val": "syncytial blastoderm stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005307", "lbl": "embryonic cycle 11", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 185." ], "definition": { "val": "The 11th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005308", "lbl": "embryonic cycle 12", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 190." ], "definition": { "val": "The 12th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005309", "lbl": "embryonic cycle 13", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 200." ], "definition": { "val": "The 13th mitotic cell cycle of embryogenesis. This occurs synchronously across the embryo.", "xrefs": [ "FlyBase:FBrf0049535" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005310", "lbl": "obsolete cellular blastoderm stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "deprecated": true }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005311", "lbl": "embryonic stage 5", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 210." ], "definition": { "val": "Cellularization. Stage 5 begins when cellularization starts. Near the end of this stage the pole cells begin to migrate dorsally and ventral midline cells acquire an irregular, wavy appearance. Stage 5 ends when ventral furrow formation becomes apparent. Duration at 25 degrees: approximately 40 minutes (130-170 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "cellular blastoderm" }, { "pred": "hasExactSynonym", "val": "cellular blastoderm stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005312", "lbl": "embryonic cycle 14", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 255. The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ], "definition": { "val": "The 14th mitotic cell cycle of embryogenesis. This is the first round of nuclear division to occur in a cellularized embryo, so this is the first round of cell division. Embryonic cycle 14 mitosis is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.", "xrefs": [ "FlyBase:FBrf0049535", "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "first blastoderm mitosis", "xrefs": [ "FlyBase:FBrf0089570" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005313", "lbl": "embryonic cycle 14A", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 256." ], "definition": { "val": "The interphase of embryonic cycle 14. This begins at the same time as cellularization and is of variable length depending on cell identity: embryonic cycle 14 M phase (14B) is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.", "xrefs": [ "[FlyBase:FBrf0039741" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "embryonic cycle 14 interphase", "xrefs": [ "FBC:DOS" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005314", "lbl": "embryonic cycle 14B", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 257. Not to be confused with mitotic domain 14B, which is a domain of cells in the dorsal midline of the head that don't undergo a 14th division (Foe, 1989). The asynchronous nature of cycle 14 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ], "definition": { "val": "The M-phase of embryonic cycle 14. This is asynchronous across the embryo, but occurs synchronously within discrete domains, known as mitotic domains.", "xrefs": [ "FlyBase:FBrf0039741" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "embryonic cycle 14 M-phase", "xrefs": [ "FBC:DOS" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005315", "lbl": "embryonic cycle 15", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 285. The asynchronous nature of cycle 15 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ], "definition": { "val": "The 15th cell cycle of embryogenesis. Asynchronous.", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "second blastoderm mitosis", "xrefs": [ "FlyBase:FBrf0089570" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005316", "lbl": "embryonic cycle 16", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 295. The asynchronous nature of cycle 16 divisions means that this is not very useful for annotating stage. If possible a standard embryonic stage should be used instead." ], "definition": { "val": "The 16th cell cycle division of embryogenesis. Asynchronous.", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "third blastoderm mitosis", "xrefs": [ "FlyBase:FBrf0089570" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005317", "lbl": "gastrula stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 220." ], "definition": { "val": "Stages during which gastrulation occurs. 6-8.", "xrefs": [ "FBC:DOS" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "gastrula" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005318", "lbl": "embryonic stage 6", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 230." ], "definition": { "val": "Stage 6 begins when the ventral furrow becomes apparent, an event which is followed rapidly by the formation of the cephalic furrow. Stage 6 ends when the pole cells have adopted a dorsal (horizontal) position at the posterior. Duration at 25 degrees C: approximately 10 minutes (170-180 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005319", "lbl": "embryonic stage 7", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 240." ], "definition": { "val": "Stage 7 begins when the pole cells have adopted a dorsal (horizontal) position at the posterior. Invagination of the anterior and posterior midgut and hindgut follows. The 'discoid plate' that carries the pole cells forms a pocket. Transverse furrows (dorsal folds) form on the dorsal surface. This stage ends when the anterior wall of the amnioproctodeal invagination starts moving anteriorly and the pole cells are no longer visible externally. Duration at 25 degrees C: approximately 10 minutes (180-190 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005320", "lbl": "obsolete germ band stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "deprecated": true }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005321", "lbl": "extended germ band stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 260." ], "definition": { "val": "Stages during which the germ band is extended - 9-12.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005322", "lbl": "embryonic stage 8", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 250." ], "definition": { "val": "Stage 8 starts with the rapid phase of germ band extension and ends with the beginning of mesodermal segmentation. By the end of this stage germ band extension has progressed to the point where the proctodeal opening is at about 60% egg length and the dorsal folds (transverse furrows) are no longer visible. Duration at 25 degrees C: approximately 30 minutes (190-220 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "rapidly extending germ band stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005323", "lbl": "embryonic stage 9", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 280." ], "definition": { "val": "Stage 9 begins when mesodermal segmentation becomes (transiently) visible, and ends with the appearance of the stomodeal invagination slightly ventral to the anterior pole. Duration at 25 degrees C: approximately 40 minutes (220-260 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005324", "lbl": "embryonic stage 10", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 290." ], "definition": { "val": "Stage 10 begins with the appearance of the stomodeal invagination, slightly ventral to the anterior pole. Periodic furrows appear in the embryonic epidermis around the middle of the stage. The germ band continues to extend, reaching its maximum extent of 75% egg length towards the end of the stage. The end of the stage is marked by the beginning of invagination of the tracheal placodes. Duration at 25 degrees : approximately 60 minutes (260-320 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005325", "lbl": "embryonic stage 11", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 310." ], "definition": { "val": "Stage 11 begins with the invagination of the tracheal placodes. Para-segmental furrow form and segment boundary furrows become deep folds. Within the head, gnathal protuberances become apparent. The end of this stage is signaled by the appearance of a distinct cleft at the posterior pole of the embryo, which becomes detached from the vitelline membrane. This marks the beginning of germ-band retraction. Duration at 25 degrees C: approximately 120 minutes (320-440 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005326", "lbl": "obsolete contracted germ band stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "deprecated": true }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005327", "lbl": "embryonic stage 12", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 320." ], "definition": { "val": "Germ band retraction. Stage 12 begins when germ-band retraction starts and ends when this process is complete so that the prospective anal plate occupies the posterior pole. During this stage the posterior and anterior midgut primordia meet and fuse and the tracheal pits fuse to form the tracheal tree. Duration at 25 degrees C: approximately 120 minutes (440-560 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "retracting germ band stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005328", "lbl": "embryonic stage 13", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 340." ], "definition": { "val": "Stage 13 begins at the completion of germ-band retraction, when the prospective anal plate occupy the posterior pole. The dorsal ridge becomes apparent externally; the clypeolabrum retracts, leaving a triangular shaped gap at the anterior pole; the labium moves to the ventral midline. This stage ends when head involution begins. Duration at 25 degrees C: Approximately 60 minutes (560-620 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "contracted germ band stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005329", "lbl": "obsolete head involution stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0100001", "val": "FBdv:00005330" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "deprecated": true }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005330", "lbl": "embryonic stage 14", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 350." ], "definition": { "val": "Stage 14 begins with the initiation of head involution. Closure of the midgut around the yolk and dorsal closure continue. Dorsal closure is 80% complete by the end of this stage. This stage ends with the appearance of the second midgut constriction. Duration at 25 degrees C: approximately 60 minutes (620-680 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "head involution stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005331", "lbl": "dorsal closure stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 330." ], "definition": { "val": "A collective term for stages 13-15.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005332", "lbl": "embryonic stage 15", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 360." ], "definition": { "val": "Stage 15 begins with the appearance of the second midgut constriction. During this stage the 1st and 3rd midgut constrictions form, dorsal closure is completed, and epidermal segmentation is accomplished. This stage ends when the intersegmental grooves can be distinguished at mid-dorsal level. Duration at 25 degrees C: approximately 100 minutes (680-780 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005333", "lbl": "late embryonic stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 370." ], "definition": { "val": "Embryonic stages 16-17.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005334", "lbl": "embryonic stage 16", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 380." ], "definition": { "val": "Stage 16 begins when the intersegmental grooves can be distinguished at mid-dorsal level, and ends when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. During this stage the ventral cord retracts to about 60% egg length. Duration at 25 degrees C: approximately 180 minutes (780-960 minutes after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005335", "lbl": "embryonic stage 17", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 390." ], "definition": { "val": "Stage 17 begins when the dorsal ridge (frontal sac) has overgrown the tip of the clypeolabrum, which is thereby enclosed in the atrium. It lasts until hatching of the embryo (approximately 24 hours after egg laying), during which time much terminal differentiation occurs, the tracheal tree fills with air, so becoming completely visible, and the ventral cord continues to retract. Duration at 25 degrees C: approximately 8 hours (16-24 hours after egg laying).", "xrefs": [ "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005336", "lbl": "larval stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 400." ], "definition": { "val": "The stage of the Drosophila life-cycle from hatching to the beginning of puparium formation.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005337", "lbl": "first instar larval stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 410." ], "definition": { "val": "The first larval instar begins at hatching and ends at the first larval molt. Anterior spiracles are not yet present; posterior spiracles have two openings each. Salivary glands are very small and all cells are uniform in size. Mouth hooks typically have one tooth. Duration at 25 degrees C: approximately 25 hours (24-49 hours after egg laying; 0-25 hours after hatching).", "xrefs": [ "FlyBase:FBrf0007733" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "L1" }, { "pred": "hasExactSynonym", "val": "first instar larva" } ], "xrefs": [ { "val": "UBERON:8000000" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005338", "lbl": "second instar larval stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 420." ], "definition": { "val": "The second larval instar begins at the first larval molt and ends at the second larval molt. Larvae are actively feeding and crawling in the food. Distinct anterior spiracles are present as enlargements at the end of the tracheal trunk, but not open to the outside; posterior spiracles have three openings each, and four groups of small unbranched hairs. The salivary glands extend to the first abdominal segment, and have cells that are uniform in size. Mouth hooks typically have two or three teeth. Duration at 25 degrees C: approximately 23 hours (49-72 hours after egg laying; 25-48 hours after hatching).", "xrefs": [ "FlyBase:FBrf0007733" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "L2" }, { "pred": "hasExactSynonym", "val": "second instar larva" } ], "xrefs": [ { "val": "UBERON:8000001" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005339", "lbl": "third instar larval stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 430." ], "definition": { "val": "The third larval instar begins at the second larval molt and ends at puparium formation. Anterior spiracles are open to the outside; posterior spiracles have three openings each, and four groups of large branched hairs. The salivary glands extend to the second abdominal segment, with cells larger in the posterior than in the anterior of the gland. Mouth hooks typically have 9-12 teeth. About 24 hours before pupariation (at 25 degree C), larvae stop feeding and climb away from their food. Duration at 25 degrees C: approximately 48 hours (72-120 hours after egg laying; 48-96 hours after hatching).", "xrefs": [ "FlyBase:FBrf0007733" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "L3" }, { "pred": "hasRelatedSynonym", "val": "third instar larva" } ], "xrefs": [ { "val": "UBERON:8000002" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005340", "lbl": "early third instar larval stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2008-11-13T11:51:56Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 440." ], "definition": { "val": "Third instar larva prior to the wandering stage (approximately the first 24 hours of the third instar larval stage under standard conditions at 25'C.).", "xrefs": [ "FlyBase:FBrf0049147" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005341", "lbl": "wandering third instar larval stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2008-11-13T11:55:46Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 460." ], "definition": { "val": "Stage of the third larval instar during which the larva wanders out of the food and climbs. Under optimum conditions at 25'C, this occurs approximately 24 hours after the start of the third instar larval stage.", "xrefs": [ "FlyBase:FBrf0049147" ] }, "synonyms": [ { "pred": "hasBroadSynonym", "val": "late third instar" }, { "pred": "hasBroadSynonym", "val": "post-feeding larva" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005342", "lbl": "prepupal stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 500." ], "definition": { "val": "The prepupal stage begins at puparium formation and ends when larval/pupal apolysis is complete, as indicated by the completion of imaginal head sac eversion and the expulsion of the oral armature of the larva. Duration at 25 degrees C: approximately 12 hours. (120-132.2 hours after egg laying; 0-12.2 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005343", "lbl": "prepupal stage P1", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 510." ], "definition": { "val": "Extends from puparium formation through tanning of the pupal cuticle. Posterior spiracles and ridge between anterior spiracles tan orange. Wriggling stops completely. Puparium becomes brown to the unaided eye. Duration at 25 degrees C: approximately 20 minutes. (120-120.3 hours after egg laying; 0-0.3 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P1" }, { "pred": "hasExactSynonym", "val": "puparium formation", "xrefs": [ "FlyBase:FBrf0036849" ] }, { "pred": "hasExactSynonym", "val": "white puparium stage", "xrefs": [ "FlyBase:FBrf0036849" ] }, { "pred": "hasNarrowSynonym", "val": "pupal stage P0", "xrefs": [ "FlyBase:FBrf0036849" ] }, { "pred": "hasNarrowSynonym", "val": "white prepupa", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005344", "lbl": "prepupal stage P2", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 520." ], "definition": { "val": "Male gonads become less distinct. Oral armature stops moving permanently. Dorsal medial abdominal contractions stop. Gas bubble becomes visible within abdomen. Duration at 25 degrees C: approximately 100 minutes. (120.3-122 hours after egg laying; 0.3-2 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P2" }, { "pred": "hasExactSynonym", "val": "brown puparium stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005345", "lbl": "prepupal stage P3", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 530." ], "definition": { "val": "Ridge of the operculum becomes distinct. Puparium begins to separate from underlying epidermis. Becomes positively buoyant. Duration at 25 degrees C: approximately 4 hours, 45 minutes. (122-126.75 hours after egg laying; 2-6.75 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P3" }, { "pred": "hasExactSynonym", "val": "bubble prepupa stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005346", "lbl": "prepupal stage P4", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 540." ], "definition": { "val": "Prepupal stage P4 begins as the lateral trunk trachea become obscured and ends when the imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 5 hours, 30 minutes. (126.75-132.2 hours after egg laying; 6.75-12.2 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P4" }, { "pred": "hasExactSynonym", "val": "cryptocephalic pupa", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005347", "lbl": "prepupal stage P4(i)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 550." ], "definition": { "val": "Lateral trunk tracheae become obscured. Dorsal medial abdominal contractions occur. Everted leg and wing discs become visible. Bubble appears in posterior of puparium, displacing the pupa anteriorly; abdominal bubble disappears. Duration at 25 degrees C: approximately 5 hours, 15 minutes. (126.75-132 hours after egg laying; 6.75-12 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P4(i)" }, { "pred": "hasExactSynonym", "val": "buoyant stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005348", "lbl": "prepupal stage P4(ii)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 560." ], "definition": { "val": "Bubble is displaced to anterior end of the puparium, and pupa withdraws to the posterior end. Imaginal head sac is everted and the oral armature of the larva is expelled. Duration at 25 degrees C: approximately 12 minutes. (132-132.2 hours after egg laying; 12-12.2 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P4(ii)" }, { "pred": "hasExactSynonym", "val": "moving bubble stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005349", "lbl": "pupal stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 570. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for Cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head and expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ], "definition": { "val": "The pupal stage starts once larval/pupal apolysis is complete as indicated by the expulsion of the larval armature. Early in this stage, the legs and wings reach full extension along the abdomen. The stage ends when the pupal cuticle separates from the underlying epidermis (pupal/adult apolysis), and the eye cup becomes yellow at its periphery. Duration at 25 degrees C: approximately 32 hours. (132.2-164.3 hours after egg laying; 12.2-44.3 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "phanerocephalic pupa", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005350", "lbl": "pupal stage P5", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 580." ], "definition": { "val": "Pupal stage P5 starts when the legs and wings reach full extension along the abdomen and ends as the Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 6 hours, 30 minutes. (132.2-138.7 hours after egg laying; 12.2-18.7 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005351", "lbl": "pupal stage P5(i)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 590." ], "definition": { "val": "Legs and wings reach full extension along abdomen. Enlarged initial segments of anterior pair Malpighian tubules move from thorax into abdomen. Translucent patch that lacks adhering fat body cells becomes discernible in the middle of the eye region. Pair of white Malpighian tubules becomes visible dorsally in the abdomen. Duration at 25 degrees C: approximately 66 minutes. (132.2-133.3 hours after egg laying; 12.2-13.3 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "Malpighian tubules migrating", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005352", "lbl": "pupal stage P5(ii)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 600." ], "definition": { "val": "Malpighian tubules become prominent and green. Duration at 25 degrees C: approximately 5 hours, 25 minutes. (133.3-138.7 hours after egg laying; 13.3-18.7 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "white Malpighian tubules stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005353", "lbl": "pupal stage P6", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 610." ], "definition": { "val": "Dark green 'yellow body' appears between the anterior ends of the two Malpighian tubule segments, mid-dorsally at the anterior of the abdomen. Duration at 25 degrees C: approximately 13 hours, 45 minutes. (138.7-152.4 hours after egg laying; 18.7-32.4 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "green Malpighian tubules stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005354", "lbl": "pupal stage P7", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 620." ], "definition": { "val": "The 'yellow body' moves back between the Malpighian tubules. The transparent pupal cuticle separates from the underlying epidermis. Eye cup becomes yellow at its perimeter. Duration at 25 degrees C: approximately 12 hours. (152.4-164.3 hours after egg laying; 32.4-44.3 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "yellow body stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005355", "lbl": "pharate adult stage P8", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 630." ], "definition": { "val": "Pale yellow pigmentation spreads inwards across the eye. Eye color becomes bright yellow, then changes to amber. Duration at 25 degrees C: approximately 12 hours 20 minutes. (164.3-176.6 hours after egg laying; 44.3-56.6 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P8" }, { "pred": "hasExactSynonym", "val": "yellow-eyed stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005356", "lbl": "pharate adult stage P9", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 640." ], "definition": { "val": "Eye color darkens to deep amber, then becomes pale pink. Duration at 25 degrees C: approximately 18 hours. (176.6-194.5 hours after egg laying; 56.6-74.5 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P9" }, { "pred": "hasExactSynonym", "val": "amber-eyed stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005357", "lbl": "pharate adult stage P10", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 650." ], "definition": { "val": "Eyes become bright red. Orbital and ocellar bristles and vibrissae darken. Duration at 25 degrees C: approximately 6 minutes. (194.5-194.6 hours after egg laying; 74.5-74.6 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P10" }, { "pred": "hasExactSynonym", "val": "red-eye bald stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005358", "lbl": "pharate adult stage P11", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 660." ], "definition": { "val": "Thoracic bristles become visible, and the tips of the wings turn grey. Duration at 25 degrees C: approximately 2 hours. (194.6-196.6 hours after egg laying; 74.6-76.6 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P11" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005359", "lbl": "pharate adult stage P11(i)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 670." ], "definition": { "val": "Dorsal thoracic microchaetes and macrochaetes become visible. Duration at 25 degrees C: approximately 80 minutes (194.6-195.5 hours after egg laying; 74.6-75.9 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P11(i)" }, { "pred": "hasExactSynonym", "val": "head bristles stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005360", "lbl": "pharate adult stage P11(ii)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 680." ], "definition": { "val": "Tips of folded wings become grey. Duration at 25 degrees C: approximately 45 minutes (195.5-196.6 hours after egg laying; 75.9-76.6 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P11(ii)" }, { "pred": "hasExactSynonym", "val": "thoracic bristles stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005361", "lbl": "pharate adult stage P12", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 690." ], "definition": { "val": "Pharate adult stage P12 begins as the abdominal tergite bristles become visible, and ends as the wings darken to black. Duration at 25 degrees C: approximately 2 hours. (196.6-198.6 hours after egg laying; 76.6-78.6 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P12" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005362", "lbl": "pharate adult stage P12(i)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 700." ], "definition": { "val": "Bristles of the abdominal tergites become visible, and the wings become grey. Duration at 25 degrees C: approximately 55 minutes. (196.6-197.5 hours after egg laying; 76.6-77.5 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P12(i)" }, { "pred": "hasExactSynonym", "val": "wing tips grey stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005363", "lbl": "pharate adult stage P12(ii)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 710." ], "definition": { "val": "Sex combs darken in males. Wings darken to black. Duration at 25 degrees C: approximately 65 minutes. (197.5-198.6 hours after egg laying; 77.5-78.6 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P12(ii)" }, { "pred": "hasExactSynonym", "val": "wings grey stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005364", "lbl": "pharate adult stage P13", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 720." ], "definition": { "val": "Tarsal bristles darken and claws become black. Duration at 25 degrees C: approximately 3 hours, 20 minutes. (198.6-201.9 hours after egg laying; 78.6-81.9 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P13" }, { "pred": "hasExactSynonym", "val": "wings black stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005365", "lbl": "pharate adult stage P14", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 730." ], "definition": { "val": "The meconium appears dorsally at the posterior tip of the abdomen. Duration at 25 degrees C: approximately 9 hours, 30 minutes (201.9-211.5 hours after egg laying; 81.9-91.5 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P14" }, { "pred": "hasExactSynonym", "val": "mature bristles stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005366", "lbl": "pharate adult stage P15", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 740." ], "definition": { "val": "Pharate adult stage P15 begins with the tanning of the tergites and ends with eclosion. Duration at 25 degrees C: approximately 8 hours, 30 minutes. (211.5-220 hours after egg laying; 91.5-100 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P15" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005367", "lbl": "pharate adult stage P15(i)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 750." ], "definition": { "val": "Tanning of the tergites obscures the Malpighian tubules and the 'yellow body'. Legs begin to twitch; fly is able to walk if puparium is removed prematurely. Ptilinum expands by hydrostatic pressure, opening the operculum. Duration at 25 degrees C: approximately 8 hours, 6 minutes. (211.5-219.6 hours after egg laying; 91.5-99.6 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P15(i)" }, { "pred": "hasExactSynonym", "val": "meconium stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005368", "lbl": "pharate adult stage P15(ii)", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 760." ], "definition": { "val": "Stage which starts when the operculum opens and ends when eclosion is completed. Duration at 25 degrees C: approximately 24 minutes. (219.6-220 hours after egg laying; 99.6-100 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "pupal stage P15(ii)" }, { "pred": "hasExactSynonym", "val": "eclosion stage", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005369", "lbl": "adult stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 770." ], "definition": { "val": "The stage of the Drosophila life-cycle from eclosion to death.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005370", "lbl": "adult stage A1", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "FBdv:00005373" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 785. The time at which eclosed flies settle down for wing expansion can vary greatly. If they fail to find a suitable site then expansion can be delayed by several hours." ], "definition": { "val": "Newly eclosed adult stage. Animal free of pupal case. Runs rapidly to find site for wing expansion. Wings are folded back and black against a very pale abdomen.", "xrefs": [ "FlyBase:FBrf0049147" ] }, "synonyms": [ { "pred": "hasRelatedSynonym", "val": "adult stage I" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005371", "lbl": "adult stage A2", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "FBdv:00005374" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 790." ], "definition": { "val": "Stage, shortly after eclosion, during which the wings expand. During wing expansion, the abdomen pulsates and the hind legs stroke the wings vigorously for several minutes at a time. The stage ends when the wings are folded down over the abdomen, which has become broader and shorter, and the wing cuticle has lost its folds. The stage lasts around 15 minutes at 25'C.", "xrefs": [ "FlyBase:FBrf0049147" ] }, "synonyms": [ { "pred": "hasRelatedSynonym", "val": "adult stage II" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00005412", "lbl": "obsolete gamete", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "This should be considered as a type of cell rather than as a stage. Please use FBbt:00005412." ], "deprecated": true }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00006011", "lbl": "pharate adult stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 625." ], "definition": { "val": "The developing adult after pupal-adult apolysis, i.e.- from stage P8 (when yellow eye color first becomes visible through the pupal case), to eclosion. Duration at 25 degrees C: approximately 55.7 hours (164.3-220 hours after egg laying; 44.3-100 hours after puparium formation).", "xrefs": [ "FlyBase:FBrf0036849", "FlyBase:FBrf0048355", "FlyBase:FBrf0049147" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00006012", "lbl": "adult stage A3", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "FBdv:00005375" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 800." ], "definition": { "val": "Adult stage immediately after wing expansion, during which tanning of the cuticle is completed. This stage lasts approximately 45 minutes at 25'C.", "xrefs": [ "FlyBase:FBrf0049147" ] }, "synonyms": [ { "pred": "hasRelatedSynonym", "val": "adult stage III" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007000", "lbl": "spermatogenesis", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2008-06-05T04:51:08Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 20000." ], "xrefs": [ { "val": "GO:0007283" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007001", "lbl": "P-stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2008-06-05T04:51:40Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 490. DISAMBIGUATION: In Drosophila lab vernacular, the term 'pupal stage' is often used to refer to the entire period from formation of the puparium to eclosion. However, this does not correspond to the standard usage of 'pupal stage' for cyclorrhaphous flies (for discussion see: FBrf0087128). Briefly: formation of the puparium (hardening of the larval cuticle) marks the beginning of the pre-pupal stage. The pupal stage begins following pupal/larval apolysis - detachment of the larval epidermis from the puparium. In Drosophila, the outward sign of the completion of apolysis is the eversion of the head an expulsion of the larval mouthparts (FBrf0036849). We use P-stage to refer to the stage from pupariation to eclosion, and restrict pupal stage to its standard usage." ], "definition": { "val": "The stage of the Drosophila life-cycle from the formation of the puparium (beginning of the prepupal stage) to eclosion.", "xrefs": [ "FBC:DOS" ] }, "synonyms": [ { "pred": "hasBroadSynonym", "val": "metamorphosis" }, { "pred": "hasRelatedSynonym", "val": "pupal stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007002", "lbl": "oogenesis stage S11a", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10140." ], "definition": { "val": "Oogenesis stage that begins when nurse cell dumping begins and development of the wax layer begins and ends when the dorsal appendages begin to form.", "xrefs": [ "FlyBase:FBrf0043885" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007003", "lbl": "oogenesis stage S11b", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10150." ], "definition": { "val": "Oogenesis stage that begins when endochorion begins to form at the anterior pole, a process which includes the beginning of formation of the dorsal appendages. During this stage, the follicle cells secrete membranous vesicles that form irregular extracellular plaques. This stage ends when dying nurse cells form an anterior cap to the oocyte.", "xrefs": [ "FlyBase:FBrf0043885" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007004", "lbl": "third instar larval stage L1", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 470." ], "definition": { "val": "Stage which begins when wandering third instar larva stops crawling. The larva everts its anterior spiracles during this stage.", "xrefs": [ "FlyBase:FBrf0036849" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007005", "lbl": "third instar larval stage L2", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 480." ], "definition": { "val": "The anterior spiracles are fully everted, with 7-9 finger-like projections. The body shortens, withdrawing three apparent abdominal segments and the larva sticks to its substrate.", "xrefs": [ "FlyBase:FBrf0036849" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "spiracles everted larva", "xrefs": [ "FlyBase:FBrf0036849" ] }, { "pred": "hasRelatedSynonym", "val": "white prepupa", "xrefs": [ "FlyBase:FBrf0036849" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007006", "lbl": "oogenesis stage S13E", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2008-11-13T06:27:57Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 10250." ], "definition": { "val": "Oogenesis stage during which the number of nurse cell nuclei at the anterior of the oocyte reduce from 4 to zero. The oocyte chromosomes reach full metaphase I during this stage, at which point meiosis is arrested (until fertilization).", "xrefs": [ "FlyBase:FBrf0029744" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007007", "lbl": "late third instar larval stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2008-12-11T01:19:53Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 450." ], "definition": { "val": "Third instar larva from the beginning of wandering to the beginning of puparium formation.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007008", "lbl": "obsolete occurrent", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "deprecated": true }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007009", "lbl": "developmental process", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2009-10-01T05:56:42Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "xrefs": [ { "val": "GO:0032502" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007011", "lbl": "embryonic cycle", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2009-10-01T05:57:41Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "A cycle of nuclear division during the embryogenesis of Drosophila melanogaster. The first 13 cycles are synchronous throughout the embryo and occur their timing relative to other developmental processes is invariant. Later nuclear division cycles are asynchronous across the embryo although may be more locally synchronized.", "xrefs": [ "FlyBase:FBrf0049535", "FlyBase:FBrf0089570" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007012", "lbl": "life stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2009-10-01T05:59:22Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "A temporal subdivision of a Drosophila life, delimited by major transitions in the circumstances of the organism, such as: fertilization; hatching; pupal ecdysis; eclosion.", "xrefs": [ "FBC:DOS" ] }, "synonyms": [ { "pred": "hasExactSynonym", "val": "life cycle stage" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007013", "lbl": "age", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2010-09-29T12:25:36Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "Temporal subdivision of life based on time elapsed since some key developmental transition, such as fertilization, hatching or eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007014", "lbl": "adult age in days", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2010-09-29T12:28:05Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "Temporal subdivision of adulthood in days post-eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007015", "lbl": "embryonic stage 17(i)", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2011-04-26T11:57:15Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 391. Should not be used to stage embryos whose development is at temperatures other than 25'C." ], "definition": { "val": "The first two hours of embryonic stage 17 at 25'C. (Approximately 16-18 hours at 25'C after egg laying).", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007016", "lbl": "embryonic stage 17(ii)", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2011-04-26T12:00:15Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 392. Should not be used to stage embryos whose development is at temperatures other than 25'C." ], "definition": { "val": "Hours 2-4 of embryonic stage 17 at 25'C. (Approximately 18-20 hours at 25'C after egg laying).", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007017", "lbl": "embryonic stage 17(iii)", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2011-04-26T12:01:18Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 393. Should not be used to stage embryos whose development is at temperatures other than 25'C." ], "definition": { "val": "Hours 4-6 of embryonic stage 17 at 25'C. (Approximately 20-22 hours at 25'C after egg laying).", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007018", "lbl": "embryonic stage 17(iv)", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2011-04-26T12:03:14Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 394. Should not be used to stage embryos whose development is at temperatures other than 25'C." ], "definition": { "val": "Hours 6-8 (the last two hours) of embryonic stage 17 at 25'C. (Approximately 22-24 hours at 25'C after egg laying).", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007019", "lbl": "third instar - uncleared gut stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 462. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with the same color guts (dark blue) as feeding larvae (Andres and Thummel, 1994). Larvae at this stage are in chromosomal puff stage 1 (Andres and Thummel, 1994)." ], "definition": { "val": "The substage of the wandering third instar larval stage, prior to the beginning of clearance of the gut.", "xrefs": [ "FlyBase:FBrf0076598" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007020", "lbl": "third instar - partially cleared gut stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 465. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with lighter colored guts (light blue) than feeding larvae (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 2-7 (Andres and Thummel, 1994)." ], "definition": { "val": "The substage of the wandering third instar larval stage when the larva has partially cleared its gut contents.", "xrefs": [ "FlyBase:FBrf0076598" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007021", "lbl": "third instar - cleared gut stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 467. This is commonly assayed by adding 0.5% bromophenol blue to the food and looking for wandering third instar larvae with guts lacking any blue stain (Andres and Thummel, 1994). Larvae at this stage are mainly in chromosomal puff stages 7-9 and pupate within 1-6 hours (Andres and Thummel, 1994." ], "definition": { "val": "The substage of the wandering third instar larval stage when the larva has cleared its gut contents.", "xrefs": [ "FlyBase:FBrf0076598" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007022", "lbl": "embryonic cycle interphase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "The interphase (GO:0051325) of an embryonic cycle.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007023", "lbl": "embryonic cycle M-phase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "The M-phase (GO:0000279) of an embryonic cycle.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007024", "lbl": "biological process", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "xrefs": [ { "val": "GO:0008150" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007025", "lbl": "immature adult stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2013-01-08T20:06:59Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 782." ], "definition": { "val": "The developmental stage that lasts from eclosion of the adult from the pupal case until tanning is complete (the end of adult stage A3).", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007026", "lbl": "mature adult stage", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "http://orcid.org/0000-0002-7073-9172" }, { "pred": "http://purl.org/dc/terms/date", "val": "2013-01-10T13:03:54Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "definition": { "val": "Life stage from the end of adult stage A3, when tanning is complete, to death.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007075", "lbl": "day 0 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 780." ], "definition": { "val": "The day of eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007076", "lbl": "day 1 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 810." ], "definition": { "val": "1st day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007077", "lbl": "day 2 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 820." ], "definition": { "val": "2nd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007078", "lbl": "day 3 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 830." ], "definition": { "val": "3rd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007079", "lbl": "day 4 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 840." ], "definition": { "val": "4th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007080", "lbl": "day 5 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 850." ], "definition": { "val": "5th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007081", "lbl": "day 6 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 860." ], "definition": { "val": "6th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007082", "lbl": "day 7 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 870." ], "definition": { "val": "7th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007083", "lbl": "day 8 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 880." ], "definition": { "val": "8th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007084", "lbl": "day 9 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 890." ], "definition": { "val": "9th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007085", "lbl": "day 10 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 900." ], "definition": { "val": "10th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007086", "lbl": "day 11 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 910." ], "definition": { "val": "11th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007087", "lbl": "day 12 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 920." ], "definition": { "val": "12th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007088", "lbl": "day 13 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 930." ], "definition": { "val": "13th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007089", "lbl": "day 14 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 940." ], "definition": { "val": "14th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007090", "lbl": "day 15 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 950." ], "definition": { "val": "15th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007091", "lbl": "day 16 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 960." ], "definition": { "val": "16th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007092", "lbl": "day 17 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 970." ], "definition": { "val": "17th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007093", "lbl": "day 18 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 980." ], "definition": { "val": "18th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007094", "lbl": "day 19 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 990." ], "definition": { "val": "19th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007095", "lbl": "day 20 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1000." ], "definition": { "val": "20th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007096", "lbl": "day 21 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1010." ], "definition": { "val": "21st day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007097", "lbl": "day 22 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1020." ], "definition": { "val": "22nd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007098", "lbl": "day 23 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1030." ], "definition": { "val": "23rd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007099", "lbl": "day 24 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1040." ], "definition": { "val": "24th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007100", "lbl": "day 25 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1050." ], "definition": { "val": "25th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007101", "lbl": "day 26 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1060." ], "definition": { "val": "26th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007102", "lbl": "day 27 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1070." ], "definition": { "val": "27th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007103", "lbl": "day 28 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1080." ], "definition": { "val": "28th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007104", "lbl": "day 29 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1090." ], "definition": { "val": "29th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007105", "lbl": "day 30 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1100." ], "definition": { "val": "30th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007106", "lbl": "day 31 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1110." ], "definition": { "val": "31st day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007107", "lbl": "day 32 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1120." ], "definition": { "val": "32nd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007108", "lbl": "day 33 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1130." ], "definition": { "val": "33rd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007109", "lbl": "day 34 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1140." ], "definition": { "val": "34th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007110", "lbl": "day 35 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1150." ], "definition": { "val": "35th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007111", "lbl": "day 36 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1160." ], "definition": { "val": "36th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007112", "lbl": "day 37 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1170." ], "definition": { "val": "37th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007113", "lbl": "day 38 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1180." ], "definition": { "val": "38th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007114", "lbl": "day 39 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1190." ], "definition": { "val": "39th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007115", "lbl": "day 40 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1200." ], "definition": { "val": "40th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007116", "lbl": "day 41 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1210." ], "definition": { "val": "41st day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007117", "lbl": "day 42 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1220." ], "definition": { "val": "42nd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007118", "lbl": "day 43 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1230." ], "definition": { "val": "43rd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007119", "lbl": "day 44 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1240." ], "definition": { "val": "44th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007120", "lbl": "day 45 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1250." ], "definition": { "val": "45th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007121", "lbl": "day 46 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1260." ], "definition": { "val": "46th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007122", "lbl": "day 47 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1270." ], "definition": { "val": "47th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007123", "lbl": "day 48 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1280." ], "definition": { "val": "48th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007124", "lbl": "day 49 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1290." ], "definition": { "val": "49th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007125", "lbl": "day 50 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1300." ], "definition": { "val": "50th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007126", "lbl": "day 51 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1310." ], "definition": { "val": "51st day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007127", "lbl": "day 52 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1320." ], "definition": { "val": "52nd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007128", "lbl": "day 53 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1330." ], "definition": { "val": "53rd day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007129", "lbl": "day 54 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1340." ], "definition": { "val": "54th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007130", "lbl": "day 55 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1350." ], "definition": { "val": "55th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007131", "lbl": "day 56 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1360." ], "definition": { "val": "56th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007132", "lbl": "day 57 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1370." ], "definition": { "val": "57th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007133", "lbl": "day 58 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1380." ], "definition": { "val": "58th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007134", "lbl": "day 59 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1390." ], "definition": { "val": "59th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00007135", "lbl": "day 60 of adulthood", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 1400." ], "definition": { "val": "60th day after eclosion.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00014201", "lbl": "early extended germ band stage", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" } ], "comments": [ "Temporal ordering number - 270." ], "definition": { "val": "A collective term for stages 9 and 10.", "xrefs": [ "FBC:DOS" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/FBdv_00018001", "lbl": "substage_of", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "relationship" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "substage_of" } ], "comments": [ "Creating this relation as a temporary fix, pending adding the axiom occurrent_part_of subproperty of happens_during to RO." ], "xrefs": [ { "val": "FBdv:00018001" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/GO_0000087", "lbl": "mitotic M phase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "definition": { "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.", "xrefs": [ "GOC:mtg_cell_cycle" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "M phase of mitotic cell cycle" }, { "pred": "hasExactSynonym", "val": "M-phase of mitotic cell cycle" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0000278", "lbl": "mitotic cell cycle", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0007067" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle." ], "definition": { "val": "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.", "xrefs": [ "GOC:mah", "ISBN:0815316194", "Reactome:69278" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms": [ { "pred": "hasRelatedSynonym", "val": "mitosis" } ], "xrefs": [ { "val": "Wikipedia:Mitosis" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0000279", "lbl": "M phase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "definition": { "val": "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.", "xrefs": [ "GOC:mtg_cell_cycle" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "M-phase" } ], "xrefs": [ { "val": "Wikipedia:M_phase" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0000280", "lbl": "nuclear division", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.", "xrefs": [ "GOC:mah" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms": [ { "pred": "hasRelatedSynonym", "val": "karyokinesis" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0003674", "lbl": "molecular_function", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "molecular process" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0006996", "lbl": "organelle organization", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "jl" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2013-12-19T15:25:51Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:1902589" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.", "xrefs": [ "GOC:mah" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "organelle organisation" }, { "pred": "hasRelatedSynonym", "val": "single-organism organelle organization" }, { "pred": "hasExactSynonym", "val": "single organism organelle organization", "xrefs": [ "GOC:TermGenie" ] }, { "pred": "hasRelatedSynonym", "val": "organelle organization and biogenesis", "xrefs": [ "GOC:dph", "GOC:jl", "GOC:mah" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0007049", "lbl": "cell cycle", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.", "xrefs": [ "GOC:go_curators", "GOC:mtg_cell_cycle" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "cell-division cycle" } ], "xrefs": [ { "val": "Wikipedia:Cell_cycle" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0007275", "lbl": "multicellular organism development", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000233", "val": "https://github.com/geneontology/go-ontology/issues/21234" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that this term was 'developmental process'." ], "definition": { "val": "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).", "xrefs": [ "GOC:dph", "GOC:ems", "GOC:isa_complete", "GOC:tb" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0008150", "lbl": "biological_process", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "jl" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2012-09-19T15:05:24Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0000004" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0007582" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0044699" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ], "definition": { "val": "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.", "xrefs": [ "GOC:pdt" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_pombe", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "biological process" }, { "pred": "hasExactSynonym", "val": "physiological process" }, { "pred": "hasRelatedSynonym", "val": "single organism process" }, { "pred": "hasRelatedSynonym", "val": "single-organism process" } ], "xrefs": [ { "val": "Wikipedia:Biological_process" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0009790", "lbl": "embryo development", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0009795" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.", "xrefs": [ "GOC:go_curators", "GOC:isa_complete", "GOC:mtg_sensu" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms": [ { "pred": "hasBroadSynonym", "val": "embryogenesis and morphogenesis" }, { "pred": "hasExactSynonym", "val": "embryogenesis" }, { "pred": "hasExactSynonym", "val": "embryonal development" } ], "xrefs": [ { "val": "Wikipedia:Embryogenesis" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0009987", "lbl": "cellular process", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "jl" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2012-12-11T16:56:55Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0008151" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0044763" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0050875" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.", "xrefs": [ "GOC:go_curators", "GOC:isa_complete" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "cell physiology" }, { "pred": "hasExactSynonym", "val": "cellular physiological process" }, { "pred": "hasNarrowSynonym", "val": "cell growth and/or maintenance" }, { "pred": "hasRelatedSynonym", "val": "single-organism cellular process" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0016043", "lbl": "cellular component organization", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0044235" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0071842" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.", "xrefs": [ "GOC:ai", "GOC:jl", "GOC:mah" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "cell organisation" }, { "pred": "hasExactSynonym", "val": "cellular component organization at cellular level" }, { "pred": "hasExactSynonym", "val": "cellular component organization in other organism" }, { "pred": "hasExactSynonym", "val": "cellular component organisation at cellular level", "xrefs": [ "GOC:mah" ] }, { "pred": "hasExactSynonym", "val": "cellular component organisation in other organism", "xrefs": [ "GOC:mah" ] }, { "pred": "hasRelatedSynonym", "val": "cell organization and biogenesis", "xrefs": [ "GOC:mah" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0022402", "lbl": "cell cycle process", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.", "xrefs": [ "GOC:isa_complete", "GOC:mtg_cell_cycle" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0022403", "lbl": "cell cycle phase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "definition": { "val": "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.", "xrefs": [ "GOC:mtg_cell_cycle" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0032501", "lbl": "multicellular organismal process", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0002161", "val": "http://purl.obolibrary.org/obo/NCBITaxon_2" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002161", "val": "http://purl.obolibrary.org/obo/NCBITaxon_2157" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002161", "val": "http://purl.obolibrary.org/obo/NCBITaxon_4896" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002161", "val": "http://purl.obolibrary.org/obo/NCBITaxon_4932" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "jl" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2012-09-19T16:07:47Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0044707" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0050874" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "Any biological process, occurring at the level of a multicellular organism, pertinent to its function.", "xrefs": [ "GOC:curators", "GOC:dph", "GOC:isa_complete", "GOC:tb" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "organismal physiological process" }, { "pred": "hasRelatedSynonym", "val": "single-multicellular organism process" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0032502", "lbl": "developmental process", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "jl" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2012-12-19T12:21:31Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0044767" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.", "xrefs": [ "GOC:isa_complete" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms": [ { "pred": "hasNarrowSynonym", "val": "development" }, { "pred": "hasRelatedSynonym", "val": "single-organism developmental process" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0044848", "lbl": "biological phase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "jl" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2014-07-16T13:12:40Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase." ], "definition": { "val": "A distinct period or stage in a biological process or cycle.", "xrefs": [ "GOC:jl" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate" ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0045448", "lbl": "mitotic cell cycle, embryonic", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.", "xrefs": [ "GOC:go_curators" ] } }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0048285", "lbl": "organelle fission", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "The creation of two or more organelles by division of one organelle.", "xrefs": [ "GOC:jid" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_yeast" ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0048856", "lbl": "anatomical structure development", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.", "xrefs": [ "GO_REF:0000021" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "development of an anatomical structure" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0051325", "lbl": "interphase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "definition": { "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.", "xrefs": [ "GOC:mtg_cell_cycle" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms": [ { "pred": "hasBroadSynonym", "val": "resting phase" }, { "pred": "hasExactSynonym", "val": "karyostasis" } ], "xrefs": [ { "val": "Wikipedia:Interphase" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0051329", "lbl": "mitotic interphase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "definition": { "val": "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.", "xrefs": [ "GOC:mtg_cell_cycle" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "interphase of mitotic cell cycle" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0071840", "lbl": "cellular component organization or biogenesis", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "mah" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2010-09-10T01:39:16Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val": "GO:0071841" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.", "xrefs": [ "GOC:mah" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_metagenomics" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "cellular component organization or biogenesis at cellular level" }, { "pred": "hasExactSynonym", "val": "cellular component organisation or biogenesis", "xrefs": [ "GOC:mah" ] }, { "pred": "hasExactSynonym", "val": "cellular component organisation or biogenesis at cellular level", "xrefs": [ "GOC:mah" ] } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0098763", "lbl": "mitotic cell cycle phase", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "comments": [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "definition": { "val": "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.", "xrefs": [ "GOC:dos" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_0140014", "lbl": "mitotic nuclear division", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000233", "val": "https://github.com/geneontology/go-ontology/issues/19910" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "pg" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-03-23T14:44:23Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.", "xrefs": [ "ISBN:0198547684" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "mitosis" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/GO_1903047", "lbl": "mitotic cell cycle process", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "jl" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2014-05-22T14:22:34Z" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "biological_process" } ], "definition": { "val": "A process that is part of the mitotic cell cycle.", "xrefs": [ "GOC:TermGenie", "GOC:mtg_cell_cycle", "GO_REF:0000060" ] }, "subsets": [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/IAO_0000115", "lbl": "definition", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000122" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/IAO_0100001", "lbl": "term replaced by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/PATO_0000001", "lbl": "quality", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "quality (PATO)" } ] }, "type": "CLASS" }, { "id": "http://purl.obolibrary.org/obo/RO_0000052", "lbl": "characteristic of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "inheres in" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this fragility is a characteristic of this vase" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this red color is a characteristic of this apple" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "inheres_in" }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" } ], "comments": [ "Note that this relation was previously called \"inheres in\", but was changed to be called \"characteristic of\" because BFO2 uses \"inheres in\" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing." ], "definition": { "val": "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000053", "lbl": "has characteristic", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "bearer of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this apple is bearer of this red color" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this vase is bearer of this fragility" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "bearer_of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "is bearer of" }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" } ], "definition": { "val": "Inverse of characteristic_of" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000056", "lbl": "participates in", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "participates in" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this blood clot participates in this blood coagulation" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this input material (or this output material) participates in this process" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this investigator participates in this investigation" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "participates_in" } ], "definition": { "val": "a relation between a continuant and a process, in which the continuant is somehow involved in the process" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000057", "lbl": "has participant", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000111", "val": "has participant" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this blood coagulation has participant this blood clot" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this investigation has participant this investigator" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this process has participant this input material (or this output material)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has_participant" }, { "pred": "http://purl.org/dc/elements/1.1/source", "val": "http://www.obofoundry.org/ro/#OBO_REL:has_participant" } ], "definition": { "val": "a relation between a process and a continuant, in which the continuant is somehow involved in the process" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000079", "lbl": "function of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this catalysis function is a function of this enzyme" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "function_of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "is function of" } ], "comments": [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ], "definition": { "val": "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000080", "lbl": "quality of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this red color is a quality of this apple" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "A quality inheres in its bearer at all times for which the quality exists." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "is quality of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "quality_of" } ], "comments": [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ], "definition": { "val": "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000081", "lbl": "role of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this investigator role is a role of this person" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "is role of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "role_of" } ], "comments": [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ], "definition": { "val": "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000085", "lbl": "has function", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has_function" } ], "definition": { "val": "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000086", "lbl": "has quality", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this apple has quality this red color" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has_quality" } ], "definition": { "val": "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000087", "lbl": "has role", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "this person has role this investigator role (more colloquially: this person has this role of investigator)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has_role" } ], "definition": { "val": "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000091", "lbl": "has disposition", "meta": { "definition": { "val": "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0000092", "lbl": "disposition of", "meta": { "comments": [ "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ], "definition": { "val": "inverse of has disposition" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002012", "lbl": "occurrent_part_of", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "occurrent_part_of" } ], "definition": { "val": "A part of relation that applies only between occurrents." }, "xrefs": [ { "val": "RO:0002012" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002013", "lbl": "has regulatory component activity", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-05-24T09:30:46Z" } ], "definition": { "val": "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002014", "lbl": "has negative regulatory component activity", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-05-24T09:31:01Z" } ], "comments": [ "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'." ], "definition": { "val": "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002015", "lbl": "has positive regulatory component activity", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-05-24T09:31:17Z" } ], "comments": [ "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'." ], "definition": { "val": "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002017", "lbl": "has component activity", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-05-24T09:44:33Z" } ], "comments": [ "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002018", "lbl": "has component process", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-05-24T09:49:21Z" } ], "definition": { "val": "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002022", "lbl": "directly regulated by", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-09-17T13:52:24Z" } ], "comments": [ "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002023", "lbl": "directly negatively regulated by", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-09-17T13:52:38Z" } ], "definition": { "val": "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.", "xrefs": [ "GOC:dos" ] } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002024", "lbl": "directly positively regulated by", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-09-17T13:52:47Z" } ], "definition": { "val": "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.", "xrefs": [ "GOC:dos" ] } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002025", "lbl": "has effector activity", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "dos" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2017-09-22T14:14:36Z" } ], "comments": [ "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations." ], "definition": { "val": "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.", "xrefs": [ "GOC:dos" ] } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002084", "lbl": "during which ends", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" } ], "comments": [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002085", "lbl": "encompasses", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "di" } ], "comments": [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002086", "lbl": "ends after", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" } ], "comments": [ "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)" ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002087", "lbl": "immediately_preceded_by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "starts_at_end_of" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "immediately_preceded_by" } ], "comments": [ "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" ], "xrefs": [ { "val": "RO:0002087" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002088", "lbl": "during which starts", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" } ], "comments": [ "Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range." ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002090", "lbl": "immediately_precedes", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "ends_at_start_of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "meets" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002575", "val": "http://purl.obolibrary.org/obo/BFO_0000063" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "FlyBase_development_CV" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "immediately_precedes" } ], "comments": [ "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)" ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ], "xrefs": [ { "val": "RO:0002090" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002091", "lbl": "starts during", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "io" } ], "comments": [ "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))" ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002092", "lbl": "happens during", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "d" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "during" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "external" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "happens_during" } ], "comments": [ "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))" ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ], "xrefs": [ { "val": "RO:0002092" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002093", "lbl": "ends during", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "o" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "overlaps" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val": "external" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#shorthand", "val": "ends_during" } ], "comments": [ "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). " ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ], "xrefs": [ { "val": "RO:0002093" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002131", "lbl": "overlaps", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000424", "val": "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)" }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" } ], "definition": { "val": "x overlaps y if and only if there exists some z such that x has part z and z part of y" }, "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002180", "lbl": "has component", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit." }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://ontologydesignpatterns.org/wiki/Submissions:Componency" } ], "definition": { "val": "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." }, "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002202", "lbl": "develops from", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Melissa Haendel" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Terry Meehan" } ], "comments": [ "This is the transitive form of the develops from relation" ], "definition": { "val": "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002203", "lbl": "develops into", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Osumi-Sutherland" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Terry Meehan" } ], "definition": { "val": "inverse of develops from" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002211", "lbl": "regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "David Hill" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Tanya Berardini" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "GO" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Regulation precludes parthood; the regulatory process may not be within the regulated process." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "regulates (processual)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000600", "val": "false" } ], "definition": { "val": "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002212", "lbl": "negatively regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "negatively regulates (process to process)" }, { "pred": "http://purl.obolibrary.org/obo/RO_0004050", "val": "http://purl.obolibrary.org/obo/RO_0002211" } ], "definition": { "val": "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002213", "lbl": "positively regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "positively regulates (process to process)" }, { "pred": "http://purl.obolibrary.org/obo/RO_0004049", "val": "http://purl.obolibrary.org/obo/RO_0002211" } ], "definition": { "val": "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002215", "lbl": "capable of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "osteoclast SubClassOf 'capable of' some 'bone resorption'" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has function realized in" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://www.ncbi.nlm.nih.gov/pubmed/20123131" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://www.ncbi.nlm.nih.gov/pubmed/21208450" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"." } ], "definition": { "val": "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " }, "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002216", "lbl": "capable of part of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has function in" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://purl.obolibrary.org/obo/ro/docs/reflexivity/" } ], "definition": { "val": "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002222", "lbl": "temporally related to", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "https://en.wikipedia.org/wiki/Allen%27s_interval_algebra" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." }, { "pred": "http://purl.org/dc/terms/source", "val": "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1" } ], "comments": [ "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ], "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002233", "lbl": "has input", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "consumes" } ], "definition": { "val": "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." }, "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco", "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002254", "lbl": "has developmental contribution from", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "x has developmental contribution from y iff x has some part z such that z develops from y" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002255", "lbl": "developmentally contributes to", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "inverse of has developmental contribution from" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002258", "lbl": "developmentally preceded by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "false" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "In general you should not use this relation to make assertions - use one of the more specific relations below this one" } ], "comments": [ "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from" ], "definition": { "val": "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002263", "lbl": "acts upstream of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision." }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of" } ], "definition": { "val": "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002264", "lbl": "acts upstream of or within", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway." }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within" } ], "definition": { "val": "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ], "synonyms": [ { "pred": "hasRelatedSynonym", "val": "affects" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002286", "lbl": "developmentally succeeded by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000125" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "Inverse of developmentally preceded by" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002304", "lbl": "causally upstream of, positive effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004049", "val": "http://purl.obolibrary.org/obo/RO_0002411" }, { "pred": "http://purl.org/dc/terms/creator", "val": "cjm" } ], "comments": [ "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y" ], "definition": { "val": "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002305", "lbl": "causally upstream of, negative effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004050", "val": "http://purl.obolibrary.org/obo/RO_0002411" }, { "pred": "http://purl.org/dc/terms/creator", "val": "cjm" } ], "definition": { "val": "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002314", "lbl": "characteristic of part of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "inheres in part of" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://www.ncbi.nlm.nih.gov/pubmed/20064205" }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://purl.obolibrary.org/obo/ro/docs/reflexivity/" } ], "definition": { "val": "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002323", "lbl": "mereotopologically related to", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships" }, { "pred": "http://purl.obolibrary.org/obo/RO_0001900", "val": "http://purl.obolibrary.org/obo/RO_0001901" } ], "definition": { "val": "A mereological relationship or a topological relationship" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002324", "lbl": "developmentally related to", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development" } ], "definition": { "val": "A relationship that holds between entities participating in some developmental process (GO:0032502)" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002327", "lbl": "enables", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "a particular instances of akt-2 enables some instance of protein kinase activity" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "catalyzes" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "executes" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "has" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "is catalyzing" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "is executing" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized." } ], "definition": { "val": "c enables p iff c is capable of p and c acts to execute p." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002328", "lbl": "functionally related to", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "This is a grouping relation that collects relations used for the purpose of connecting structure and function" } ], "definition": { "val": "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002329", "lbl": "part of structure that is capable of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "false" } ], "definition": { "val": "this relation holds between c and p when c is part of some c', and c' is capable of p." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002331", "lbl": "involved in", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "actively involved in" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "enables part of" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://wiki.geneontology.org/index.php/Involved_in" } ], "definition": { "val": "c involved_in p if and only if c enables some process p', and p' is part of p" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002333", "lbl": "enabled by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "inverse of enables" }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002334", "lbl": "regulated by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "regulated by (processual)" } ], "definition": { "val": "inverse of regulates" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002335", "lbl": "negatively regulated by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "inverse of negatively regulates" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002336", "lbl": "positively regulated by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "inverse of positively regulates" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002352", "lbl": "input of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "inverse of has input" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259", "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002384", "lbl": "has developmental potential involving", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000428" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002385", "lbl": "has potential to developmentally contribute to", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000428" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002387", "lbl": "has potential to develop into", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000428" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "x has the potential to develop into y iff x develops into y or if x is capable of developing into y" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002388", "lbl": "has potential to directly develop into", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000428" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002404", "lbl": "causally downstream of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000428" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "inverse of upstream of" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002405", "lbl": "immediately causally downstream of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000114", "val": "http://purl.obolibrary.org/obo/IAO_0000428" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002407", "lbl": "indirectly positively regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "indirectly activates" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002579", "val": "http://purl.obolibrary.org/obo/RO_0002213" } ], "definition": { "val": "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002409", "lbl": "indirectly negatively regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "indirectly inhibits" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002579", "val": "http://purl.obolibrary.org/obo/RO_0002212" } ], "definition": { "val": "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002410", "lbl": "causally related to", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative?\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." } ], "definition": { "val": "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.", "xrefs": [ "https://en.wikipedia.org/wiki/Causality" ] } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002411", "lbl": "causally upstream of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002412", "lbl": "immediately causally upstream of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002575", "val": "http://purl.obolibrary.org/obo/RO_0002411" } ], "definition": { "val": "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002418", "lbl": "causally upstream of or within", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "influences (processual)" } ], "definition": { "val": "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." }, "synonyms": [ { "pred": "hasRelatedSynonym", "val": "affects" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002427", "lbl": "causally downstream of or within", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" } ], "definition": { "val": "inverse of causally upstream of or within" }, "subsets": [ "http://purl.obolibrary.org/obo/RO_0002259" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002428", "lbl": "involved in regulation of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "c involved in regulation of p if c is involved in some p' and p' regulates some p" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002429", "lbl": "involved in positive regulation of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/RO_0004049", "val": "http://purl.obolibrary.org/obo/RO_0002428" } ], "definition": { "val": "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002430", "lbl": "involved in negative regulation of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/RO_0004050", "val": "http://purl.obolibrary.org/obo/RO_0002428" } ], "definition": { "val": "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002431", "lbl": "involved in or involved in regulation of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "OWL does not allow defining object properties via a Union" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "involved in or reguates" } ], "definition": { "val": "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002434", "lbl": "interacts with", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Considering relabeling as 'pairwise interacts with'" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules." }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" }, { "pred": "http://www.w3.org/2004/02/skos/core#closeMatch", "val": "http://purl.obolibrary.org/obo/MI_0914" } ], "definition": { "val": "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." }, "subsets": [ "http://purl.obolibrary.org/obo/ro/subsets#ro-eco" ], "synonyms": [ { "pred": "hasExactSynonym", "val": "in pairwise interaction with" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002436", "lbl": "molecularly interacts with", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "binds" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "molecularly binds with" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://purl.obolibrary.org/obo/ECO_0000353" }, { "pred": "http://www.w3.org/2004/02/skos/core#closeMatch", "val": "http://purl.obolibrary.org/obo/MI_0915" } ], "definition": { "val": "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002447", "lbl": "phosphorylates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Axiomatization to GO to be added later" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y." } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002448", "lbl": "directly regulates activity of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Vasundra Touré" } ], "definition": { "val": "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B." }, "synonyms": [ { "pred": "hasExactSynonym", "val": "molecularly controls" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002449", "lbl": "directly negatively regulates activity of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Vasundra Touré" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "directly inhibits" } ], "definition": { "val": "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B." }, "synonyms": [ { "pred": "hasExactSynonym", "val": "molecularly decreases activity of" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002450", "lbl": "directly positively regulates activity of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Vasundra Touré" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000118", "val": "directly activates" } ], "definition": { "val": "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B." }, "synonyms": [ { "pred": "hasExactSynonym", "val": "molecularly increases activity of" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002464", "lbl": "helper property (not for use in curation)", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning." } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002481", "lbl": "is kinase activity", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002500", "lbl": "causal agent in process", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" } ], "definition": { "val": "A relationship between a material entity and a process where the material entity has some causal role that influences the process" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002501", "lbl": "causal relation between processes", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." } ], "definition": { "val": "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002502", "lbl": "depends on", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://purl.obolibrary.org/obo/BFO_0000169" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002506", "lbl": "causal relation between entities", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002559", "lbl": "causally influenced by", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "causally influenced by (entity-centric)" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002563", "lbl": "interaction relation helper property", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002564", "lbl": "molecular interaction relation helper property", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002566", "lbl": "causally influences", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Vasundra Touré" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "causally influences (entity-centric)" } ], "definition": { "val": "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002578", "lbl": "directly regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "directly regulates (processual)" }, { "pred": "http://purl.obolibrary.org/obo/RO_0002575", "val": "http://purl.obolibrary.org/obo/RO_0002211" } ], "definition": { "val": "p directly regulates q iff p is immediately causally upstream of q and p regulates q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002581", "lbl": "is a defining property chain axiom", "meta": { "definition": { "val": "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002582", "lbl": "is a defining property chain axiom where second argument is reflexive", "meta": { "definition": { "val": "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002584", "lbl": "has part structure that is capable of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" } ], "definition": { "val": "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002595", "lbl": "causal relation between material entity and a process", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000116", "val": "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Chris Mungall" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" } ], "definition": { "val": "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002596", "lbl": "capable of regulating", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "pyrethroid -> growth" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" } ], "definition": { "val": "Holds between c and p if and only if c is capable of some activity a, and a regulates p." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002597", "lbl": "capable of negatively regulating", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" } ], "definition": { "val": "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002598", "lbl": "capable of positively regulating", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "renin -> arteriolar smooth muscle contraction" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" } ], "definition": { "val": "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002608", "lbl": "process has causal agent", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" } ], "definition": { "val": "Inverse of 'causal agent in process'" } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002629", "lbl": "directly positively regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "directly positively regulates (process to process)" }, { "pred": "http://purl.obolibrary.org/obo/RO_0004049", "val": "http://purl.obolibrary.org/obo/RO_0002578" } ], "definition": { "val": "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0002630", "lbl": "directly negatively regulates", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000119", "val": "http://purl.obolibrary.org/obo/ro/docs/causal-relations" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000589", "val": "directly negatively regulates (process to process)" }, { "pred": "http://purl.obolibrary.org/obo/RO_0004050", "val": "http://purl.obolibrary.org/obo/RO_0002578" } ], "definition": { "val": "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_annotation_extension", "http://purl.obolibrary.org/obo/valid_for_go_ontology", "http://purl.obolibrary.org/obo/valid_for_gocam" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0004031", "lbl": "enables subfunction", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "cjm" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2018-01-25T23:20:13Z" } ], "definition": { "val": "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0004032", "lbl": "acts upstream of or within, positive effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004049", "val": "http://purl.obolibrary.org/obo/RO_0002264" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "cjm" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2018-01-26T23:49:30Z" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect" } ], "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0004033", "lbl": "acts upstream of or within, negative effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004050", "val": "http://purl.obolibrary.org/obo/RO_0002264" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "cjm" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2018-01-26T23:49:51Z" } ], "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0004034", "lbl": "acts upstream of, positive effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004049", "val": "http://purl.obolibrary.org/obo/RO_0002263" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "cjm" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2018-01-26T23:53:14Z" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect" } ], "definition": { "val": "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0004035", "lbl": "acts upstream of, negative effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004050", "val": "http://purl.obolibrary.org/obo/RO_0002263" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "cjm" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2018-01-26T23:53:22Z" }, { "pred": "http://www.w3.org/2000/01/rdf-schema#seeAlso", "val": "http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect" } ], "definition": { "val": "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" }, "subsets": [ "http://purl.obolibrary.org/obo/valid_for_go_gp2term" ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0004046", "lbl": "causally upstream of or within, negative effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004050", "val": "http://purl.obolibrary.org/obo/RO_0002418" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "cjm" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2018-03-13T23:55:05Z" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0004047", "lbl": "causally upstream of or within, positive effect", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/RO_0004049", "val": "http://purl.obolibrary.org/obo/RO_0002418" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "cjm" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2018-03-13T23:55:19Z" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0011002", "lbl": "regulates activity of", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "Vasundra Touré" } ], "definition": { "val": "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0012011", "lbl": "indirectly causally upstream of", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "pg" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2022-09-26T06:07:17Z" } ], "definition": { "val": "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0012012", "lbl": "indirectly regulates", "meta": { "basicPropertyValues": [ { "pred": "http://www.geneontology.org/formats/oboInOwl#created_by", "val": "pg" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2022-09-26T06:08:01Z" } ], "definition": { "val": "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0017001", "lbl": "device utilizes material", "meta": { "basicPropertyValues": [ { "pred": "http://purl.obolibrary.org/obo/IAO_0000112", "val": "A diagnostic testing device utilizes a specimen." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "https://orcid.org/0000-0001-9625-1899" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000117", "val": "https://orcid.org/0000-0003-2620-0345" }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input." }, { "pred": "http://purl.obolibrary.org/obo/IAO_0000232", "val": "See github ticket https://github.com/oborel/obo-relations/issues/497" }, { "pred": "http://www.geneontology.org/formats/oboInOwl#creation_date", "val": "2021-11-08T12:00:00Z" } ], "definition": { "val": "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." }, "synonyms": [ { "pred": "hasBroadSynonym", "val": "utilizes" } ] }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0019000", "lbl": "regulates characteristic", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": "https://orcid.org/0000-0002-8688-6599" } ], "definition": { "val": "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." } }, "type": "PROPERTY" }, { "id": "http://purl.obolibrary.org/obo/RO_0019001", "lbl": "positively regulates characteristic", "meta": { "basicPropertyValues": [ { "pred": "http://purl.org/dc/terms/contributor", "val": 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