format-version: 1.2 data-version: fbcv/releases/2021-10-18 date: 18:10:2021 13:03 subsetdef: 1_STAR "" subsetdef: 2_STAR "" subsetdef: 3_STAR "" subsetdef: abnormal_slim "Abnormal/normal slim" subsetdef: absent_slim "Absent/present slim" subsetdef: attribute_slim "Attribute slim" subsetdef: camcur "" subsetdef: camcur "camcur" subsetdef: cell_quality "cell_quality" subsetdef: common_tool_use "Terms to summarize typical use of a gene from one organism that is introduced into another organism primarily for use an experimental tool, rather than to study the function of the gene" subsetdef: cur "cur" subsetdef: deprecated "warning of impending obsoletion" subsetdef: do_not_annotate "Term not to be used for direct annotation" subsetdef: do_not_manually_annotate "Term not to be used for direct manual annotation" subsetdef: EmbDevSlim "EmbDevSlim" subsetdef: fbcvsubset_mgiribbons "MGI ribbon terms" subsetdef: FlyTed "Testis slim" subsetdef: FT_new "FlyTed temp subset for edit tracking purposes" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_ontology "" subsetdef: http://purl.obolibrary.org/obo/valid_for_gocam "" subsetdef: larval_OF "larval olfactory system" subsetdef: lethal_phase "lethal phase terms" subsetdef: RD "terms for rd test ontology" subsetdef: relational_slim "Relational slim: types of quality that require an additional entity in order to exist" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: value_slim "Value slim" synonymtypedef: BRAIN_NAME_ABV "BrainName official abbreviation" synonymtypedef: BRAND_NAME "BRAND NAME" synonymtypedef: FORMULA "FORMULA" synonymtypedef: InChI "InChI" synonymtypedef: InChIKey "InChIKey" synonymtypedef: INN "INN" synonymtypedef: IUPAC_NAME "IUPAC NAME" synonymtypedef: SMILES "SMILES" synonymtypedef: systematic_synonym "Systematic synonym" EXACT default-namespace: FlyBase miscellaneous CV ontology: fbcv.obo property_value: attributionURL http://dx.doi.org/10.1186/2041-1480-4-30 xsd:string property_value: dc-description "A miscellaneous ontology of terms used for curation in FlyBase, including the DPO." xsd:string property_value: dc-title "FlyBase Controlled Vocabulary (FBcv)" xsd:string property_value: dcterms-license https://creativecommons.org/licenses/by/3.0/ xsd:string property_value: http://purl.org/dc/elements/1.1/creator http://orcid.org/0000-0002-1373-1705 xsd:string property_value: http://purl.org/dc/elements/1.1/creator http://orcid.org/0000-0002-7073-9172 xsd:string property_value: http://purl.org/dc/elements/1.1/creator https://orcid.org/0000-0001-5948-3092 xsd:string property_value: http://purl.org/dc/elements/1.1/creator https://orcid.org/0000-0002-0027-0858 xsd:string property_value: IAO:0000700 FBcv:0000000 property_value: owl:versionInfo "2021-10-18" xsd:string [Term] id: BFO:0000002 name: continuant def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." [] disjoint_from: BFO:0000003 ! occurrent relationship: part_of BFO:0000002 ! continuant [Term] id: BFO:0000003 name: occurrent def: "An entity that has temporal parts and that happens, unfolds or develops through time." [] relationship: part_of BFO:0000003 ! occurrent [Term] id: BFO:0000004 name: independent continuant def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." [] is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000004 ! independent continuant [Term] id: BFO:0000015 name: process def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." [] is_a: BFO:0000003 ! occurrent [Term] id: BFO:0000016 name: disposition is_a: BFO:0000017 ! realizable entity disjoint_from: BFO:0000023 ! role [Term] id: BFO:0000017 name: realizable entity def: "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." [] is_a: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000019 ! quality relationship: part_of BFO:0000017 ! realizable entity [Term] id: BFO:0000019 name: quality is_a: BFO:0000020 ! specifically dependent continuant relationship: part_of BFO:0000019 ! quality [Term] id: BFO:0000020 name: specifically dependent continuant def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." [] is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000020 ! specifically dependent continuant [Term] id: BFO:0000023 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." [] is_a: BFO:0000017 ! realizable entity [Term] id: BFO:0000031 name: generically dependent continuant def: "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time." [] is_a: BFO:0000002 ! continuant relationship: part_of BFO:0000031 ! generically dependent continuant [Term] id: BFO:0000034 name: function is_a: BFO:0000016 ! disposition [Term] id: BFO:0000040 name: material entity def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." [] is_a: BFO:0000004 ! independent continuant [Term] id: CARO:0000000 name: anatomical entity is_a: CARO:0030000 ! biological entity property_value: IAO:0000412 http://purl.obolibrary.org/obo/caro.owl [Term] id: CARO:0030000 name: biological entity is_a: BFO:0000004 ! independent continuant [Term] id: CHEBI:10432 name: 2-naphthol namespace: chebi_ontology def: "A naphthol carrying a hydroxy group at position 2." [] subset: 3_STAR synonym: "2-hydroxynaphthalene" RELATED [HMDB] synonym: "2-Naftol" RELATED [ChemIDplus] synonym: "2-naftolo" RELATED [ChemIDplus] synonym: "2-naphthalenol" RELATED [NIST_Chemistry_WebBook] synonym: "2-Naphthol" EXACT [KEGG_COMPOUND] synonym: "2-naphthol" EXACT [UniProt] synonym: "2-naphtol" RELATED [ChemIDplus] synonym: "Antioxygene BN" RELATED BRAND_NAME [HMDB] synonym: "Azogen Developer A" RELATED BRAND_NAME [HMDB] synonym: "beta-hydroxynaphthalene" RELATED [NIST_Chemistry_WebBook] synonym: "beta-hydroxynaphthalene" RELATED [ChemIDplus] synonym: "beta-Naftol" RELATED [ChemIDplus] synonym: "beta-naftolo" RELATED [ChemIDplus] synonym: "beta-Naphthol" RELATED [KEGG_COMPOUND] synonym: "beta-naphthol" RELATED [NIST_Chemistry_WebBook] synonym: "beta-naphthyl alcohol" RELATED [ChemIDplus] synonym: "beta-naphthyl hydroxide" RELATED [ChemIDplus] synonym: "beta-Naphtol" RELATED [ChemIDplus] synonym: "C.I. Azoic Coupling Component 1" RELATED BRAND_NAME [ChemIDplus] synonym: "C.I. Developer 5" RELATED BRAND_NAME [ChemIDplus] synonym: "Developer A" RELATED BRAND_NAME [ChemIDplus] synonym: "Developer AMS" RELATED BRAND_NAME [ChemIDplus] synonym: "Developer BN" RELATED BRAND_NAME [ChemIDplus] synonym: "Isonaphthol" RELATED [ChemIDplus] synonym: "naphthalen-2-ol" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:742134 {source="Beilstein"} xref: CAS:135-19-3 {source="NIST Chemistry WebBook"} xref: CAS:135-19-3 {source="ChemIDplus"} xref: CAS:135-19-3 {source="KEGG COMPOUND"} xref: Drug_Central:3370 {source="DrugCentral"} xref: FooDB:FDB000877 xref: Gmelin:27395 {source="Gmelin"} xref: HMDB:HMDB0012322 xref: KEGG:C11713 xref: MetaCyc:CPD-8131 xref: PDBeChem:03V xref: PMID:13386410 {source="Europe PMC"} xref: PMID:14751800 {source="Europe PMC"} xref: PMID:18515997 {source="Europe PMC"} xref: PMID:18856458 {source="Europe PMC"} xref: PMID:20260560 {source="Europe PMC"} xref: PMID:22069470 {source="Europe PMC"} xref: PMID:22740618 {source="Europe PMC"} xref: PMID:23344974 {source="Europe PMC"} xref: PMID:29987264 {source="Europe PMC"} xref: PMID:30572877 {source="Europe PMC"} xref: PMID:30828382 {source="Europe PMC"} xref: PMID:32206945 {source="Europe PMC"} xref: PMID:33862438 {source="Europe PMC"} xref: PMID:34033865 {source="Europe PMC"} xref: Reaxys:742134 {source="Reaxys"} xref: Wikipedia:2-Naphthol is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35682 ! naphthol relationship: has_role CHEBI:35444 ! antinematodal drug relationship: has_role CHEBI:48578 ! radical scavenger relationship: has_role CHEBI:50902 ! genotoxin relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76967 ! human xenobiotic metabolite relationship: has_role CHEBI:84087 ! human urinary metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H8O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JWAZRIHNYRIHIV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "144.173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "144.05751" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC1=CC2=CC=CC=C2C=C1" xsd:string [Term] id: CHEBI:10545 name: electron namespace: chebi_ontology def: "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." [] subset: 3_STAR synonym: "beta" RELATED [IUPAC] synonym: "beta(-)" RELATED [ChEBI] synonym: "beta-particle" RELATED [IUPAC] synonym: "e" RELATED [IUPAC] synonym: "e(-)" RELATED [UniProt] synonym: "e-" RELATED [KEGG_COMPOUND] synonym: "electron" EXACT [KEGG_COMPOUND] synonym: "electron" EXACT IUPAC_NAME [IUPAC] synonym: "electron" EXACT [ChEBI] synonym: "Elektron" RELATED [ChEBI] synonym: "negatron" RELATED [IUPAC] xref: KEGG:C05359 xref: PMID:21614077 {source="Europe PMC"} xref: Wikipedia:Electron is_a: CHEBI:36338 ! lepton property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.000548579903" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string [Term] id: CHEBI:131927 name: dicarboxylic acids and O-substituted derivatives namespace: chebi_ontology def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." [] subset: 3_STAR synonym: "dicarboxylic acids and derivatives" RELATED [ChEBI] is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:132124 name: 1,4-benzoquinones namespace: chebi_ontology def: "Any member of the class of benzoquinones that is 1,4-benzoquinone or its C-substituted derivatives." [] subset: 3_STAR synonym: "a quinone" RELATED [UniProt] synonym: "p-benzoquinones" RELATED [ChEBI] synonym: "para-benzoquinones" RELATED [ChEBI] is_a: CHEBI:22729 ! benzoquinones is_a: CHEBI:25830 ! p-quinones property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6O2R4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "104.063" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "103.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C1C(*)=C(*)C(=O)C(*)=C1*" xsd:string [Term] id: CHEBI:134179 name: volatile organic compound namespace: chebi_ontology def: "Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa." [] subset: 3_STAR synonym: "VOC" RELATED [ChEBI] synonym: "VOCs" RELATED [ChEBI] synonym: "volatile organic compounds" RELATED [ChEBI] xref: Wikipedia:Volatile_organic_compound is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:134249 name: alkanesulfonate oxoanion namespace: chebi_ontology alt_id: CHEBI:22318 def: "An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups." [] subset: 3_STAR synonym: "alkanesulfonate oxoanions" RELATED [ChEBI] synonym: "alkanesulfonates" RELATED [ChEBI] synonym: "an alkanesulfonate" RELATED [UniProt] xref: MetaCyc:Alkanesulfonates is_a: CHEBI:33554 ! organosulfonate oxoanion property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O3SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "94.091" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "93.97246" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(S([O-])(=O)=O)*" xsd:string [Term] id: CHEBI:13643 name: glycol namespace: chebi_ontology def: "A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent." [] subset: 3_STAR synonym: "glycols" EXACT IUPAC_NAME [IUPAC] synonym: "Glykol" RELATED [ChEBI] is_a: CHEBI:23824 ! diol [Term] id: CHEBI:136859 name: pro-agent namespace: chebi_ontology def: "A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent." [] subset: 3_STAR synonym: "pro-agents" RELATED [ChEBI] synonym: "proagent" RELATED [ChEBI] synonym: "proagents" RELATED [ChEBI] xref: PMID:26449612 {source="Europe PMC"} is_a: CHEBI:33232 ! application [Term] id: CHEBI:137980 name: metalloid atom namespace: chebi_ontology def: "An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included." [] subset: 3_STAR synonym: "metalloid" RELATED [ChEBI] synonym: "metalloids" RELATED [ChEBI] xref: Wikipedia:Metalloid is_a: CHEBI:33250 ! atom [Term] id: CHEBI:137982 name: tertiary ammonium ion namespace: chebi_ontology def: "An organic cation obtained by protonation of the amino group of any tertiary amino compound." [] subset: 3_STAR synonym: "a tertiary amine" RELATED [UniProt] synonym: "tertiary amine(1+)" RELATED [ChEBI] synonym: "tertiary ammonium ions" RELATED [ChEBI] is_a: CHEBI:25697 ! organic cation relationship: is_conjugate_acid_of CHEBI:50996 ! tertiary amino compound property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HNR3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.015" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.01090" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH+](*)(*)*" xsd:string [Term] id: CHEBI:138015 name: endocrine disruptor namespace: chebi_ontology def: "Any compound that can disrupt the functions of the endocrine (hormone) system" [] subset: 3_STAR synonym: "endocrine disrupting chemical" RELATED [ChEBI] synonym: "endocrine disrupting chemicals" RELATED [ChEBI] synonym: "endocrine disrupting compound" RELATED [ChEBI] synonym: "endocrine disrupting compounds" RELATED [ChEBI] synonym: "endocrine disruptors" RELATED [ChEBI] synonym: "endocrine-disrupting chemical" RELATED [ChEBI] synonym: "endocrine-disrupting chemicals" RELATED [ChEBI] synonym: "hormonally active agent" RELATED [ChEBI] synonym: "hormonally active agents" RELATED [ChEBI] xref: PMID:27929035 {source="Europe PMC"} xref: PMID:28356401 {source="Europe PMC"} xref: PMID:28526231 {source="Europe PMC"} xref: Wikipedia:Endocrine_disruptor is_a: CHEBI:51061 ! hormone receptor modulator [Term] id: CHEBI:138103 name: inorganic acid namespace: chebi_ontology def: "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." [] subset: 3_STAR synonym: "inorganic acids" RELATED [ChEBI] synonym: "mineral acid" RELATED [ChEBI] synonym: "mineral acids" RELATED [ChEBI] xref: Wikipedia:Mineral_acid is_a: CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:138675 name: gas molecular entity namespace: chebi_ontology def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." [] subset: 3_STAR synonym: "gas molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entity" RELATED [ChEBI] xref: Wikipedia:https\://en.wikipedia.org/wiki/Gas is_a: CHEBI:33579 ! main group molecular entity [Term] id: CHEBI:139358 name: isotopically modified compound namespace: chebi_ontology def: "Any molecular entity in which the isotopic ratio of nuclides for at least one element deviates measurably from that occurring in nature. The term includes both isotopically substituted compounds (in which essentially all the molecules of the compound have only the indicated nuclide(s) at each designated position) and isotopically labeled compounds (a formal mixture of an isotopically unmodified compound with one or more analogous isotopically substituted compound(s)." [] subset: 3_STAR synonym: "isotopically modified compounds" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:139359 name: tritiated compound namespace: chebi_ontology def: "Any isotopically modified compound that has one or more hydrogens replaced by tritium." [] subset: 3_STAR synonym: "(3)H-labeled compound" RELATED [ChEBI] synonym: "(3)H-labeled compounds" RELATED [ChEBI] synonym: "(3)H-labelled compound" RELATED [ChEBI] synonym: "(3)H-labelled compounds" RELATED [ChEBI] synonym: "tritiated compounds" RELATED [ChEBI] synonym: "tritium-labeled compound" RELATED [ChEBI] synonym: "tritium-labeled compounds" RELATED [ChEBI] synonym: "tritium-labelled compound" RELATED [ChEBI] synonym: "tritium-labelled compounds" RELATED [ChEBI] is_a: CHEBI:139358 ! isotopically modified compound [Term] id: CHEBI:13941 name: carbamate namespace: chebi_ontology subset: 3_STAR synonym: "Carbamat" RELATED [ChEBI] synonym: "carbamate" EXACT [UniProt] synonym: "carbamate" EXACT IUPAC_NAME [IUPAC] synonym: "carbamate ion" RELATED [ChemIDplus] synonym: "carbamic acid, ion(1-)" RELATED [ChemIDplus] synonym: "Karbamat" RELATED [ChEBI] xref: Beilstein:3903503 {source="Beilstein"} xref: CAS:302-11-4 {source="ChemIDplus"} xref: Gmelin:239604 {source="Gmelin"} is_a: CHEBI:37022 ! amino-acid anion is_a: FBcv:0000538 ! carbamate equivalent_to: FBcv:0000538 ! carbamate relationship: is_conjugate_base_of CHEBI:28616 ! carbamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.03212" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.00910" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([O-])=O" xsd:string [Term] id: CHEBI:139492 name: sensitiser namespace: chebi_ontology def: "A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound." [] subset: 3_STAR synonym: "sensitisers" RELATED [ChEBI] synonym: "sensitizer" RELATED [ChEBI] synonym: "sensitizers" RELATED [ChEBI] is_a: CHEBI:52209 ! aetiopathogenetic role [Term] id: CHEBI:140332 name: 4'-methoxyflavanones namespace: chebi_ontology def: "Any methoxyflavanone having a methoxy substituent located at position 4'." [] subset: 3_STAR synonym: "2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one" EXACT IUPAC_NAME [IUPAC] synonym: "a 4'-methoxyflavanone" RELATED [UniProt] xref: MetaCyc:4-Methoxyflavanones {source="SUBMITTER"} is_a: CHEBI:25240 ! methoxyflavanone property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C16H5O3R9" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "245.210" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "245.02387" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C(C2=C1OC(C(C2=O)*)C3=C(C(=C(C(=C3*)*)OC)*)*)*)*)*)*" xsd:string [Term] id: CHEBI:14321 name: glutamate(1-) namespace: chebi_ontology def: "An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group" [] subset: 3_STAR synonym: "2-ammoniopentanedioate" RELATED [IUPAC] synonym: "glutamate" RELATED [UniProt] synonym: "glutamate(1-)" EXACT [JCBN] synonym: "glutamic acid monoanion" RELATED [JCBN] synonym: "hydrogen glutamate" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:327908 {source="Gmelin"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33558 ! alpha-amino-acid anion relationship: has_role CHEBI:78675 ! fundamental metabolite relationship: is_conjugate_acid_of CHEBI:29987 ! glutamate(2-) relationship: is_conjugate_base_of CHEBI:18237 ! glutamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H8NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "146.12136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.04588" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C(CCC([O-])=O)C([O-])=O" xsd:string [Term] id: CHEBI:149552 name: emetic namespace: chebi_ontology def: "Any agent that induces nausea and vomiting." [] subset: 3_STAR synonym: "emetics" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:15318 name: xanthine namespace: chebi_ontology def: "A purine nucleobase found in humans and other organisms." [] subset: 3_STAR synonym: "2,6-dioxopurine" RELATED [ChEBI] synonym: "2,6-dioxopurines" RELATED [ChEBI] synonym: "xanthine" EXACT [ChEBI] synonym: "xanthines" RELATED [ChEBI] xref: ECMDB:ECMDB00292 xref: KNApSAcK:C00019660 xref: PMID:1557408 {source="Europe PMC"} xref: PMID:24629268 {source="Europe PMC"} xref: PMID:9007687 {source="Europe PMC"} xref: YMDB:YMDB00263 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25810 ! oxopurine is_a: CHEBI:26386 ! purine nucleobase relationship: has_functional_parent CHEBI:16235 ! guanine relationship: has_role CHEBI:78675 ! fundamental metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H4N4O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "152.111" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "152.03343" xsd:string [Term] id: CHEBI:15339 name: acceptor namespace: chebi_ontology alt_id: CHEBI:13699 alt_id: CHEBI:2377 def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." [] subset: 3_STAR synonym: "A" RELATED [KEGG_COMPOUND] synonym: "accepteur" RELATED [ChEBI] synonym: "Acceptor" EXACT [KEGG_COMPOUND] synonym: "Akzeptor" RELATED [ChEBI] synonym: "Hydrogen-acceptor" RELATED [KEGG_COMPOUND] synonym: "Oxidized donor" RELATED [KEGG_COMPOUND] xref: KEGG:C00028 xref: KEGG:C16722 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:15356 name: cysteine namespace: chebi_ontology alt_id: CHEBI:14061 alt_id: CHEBI:23508 alt_id: CHEBI:4050 def: "A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3." [] subset: 3_STAR synonym: "2-amino-3-mercaptopropanoic acid" RELATED [JCBN] synonym: "2-Amino-3-mercaptopropionic acid" RELATED [KEGG_COMPOUND] synonym: "2-amino-3-sulfanylpropanoic acid" RELATED [IUPAC] synonym: "C" RELATED [ChEBI] synonym: "cisteina" RELATED [ChEBI] synonym: "Cys" RELATED [ChEBI] synonym: "Cystein" RELATED [ChEBI] synonym: "Cysteine" EXACT [KEGG_COMPOUND] synonym: "cysteine" EXACT IUPAC_NAME [IUPAC] synonym: "cysteine" EXACT [ChEBI] synonym: "Hcys" RELATED [IUPAC] synonym: "Zystein" RELATED [ChEBI] xref: Beilstein:1721406 {source="Beilstein"} xref: CAS:3374-22-9 {source="ChemIDplus"} xref: CAS:3374-22-9 {source="NIST Chemistry WebBook"} xref: CAS:3374-22-9 {source="KEGG COMPOUND"} xref: Gmelin:2933 {source="Gmelin"} xref: KEGG:C00736 xref: KNApSAcK:C00001351 xref: KNApSAcK:C00007323 xref: PMID:17439666 {source="Europe PMC"} xref: PMID:25181601 {source="Europe PMC"} xref: Reaxys:1721406 {source="Reaxys"} xref: Wikipedia:Cysteine is_a: CHEBI:26167 ! polar amino acid is_a: CHEBI:26834 ! sulfur-containing amino acid is_a: CHEBI:33704 ! alpha-amino acid relationship: has_part CHEBI:50326 ! sulfanylmethyl group relationship: has_role CHEBI:78675 ! fundamental metabolite relationship: is_conjugate_acid_of CHEBI:32456 ! cysteinate(1-) relationship: is_conjugate_base_of CHEBI:32458 ! cysteinium relationship: is_tautomer_of CHEBI:35237 ! cysteine zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H7NO2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "121.15922" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "121.01975" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(CS)C(O)=O" xsd:string [Term] id: CHEBI:15369 name: actinomycin namespace: chebi_ontology alt_id: CHEBI:13723 alt_id: CHEBI:22220 alt_id: CHEBI:2445 def: "A large group of antibiotics isolated from various species of Streptomyces and characterised by having a substituted phenoxazine ring linked to two cyclic heterodetic peptides." [] subset: 3_STAR synonym: "Actinomycin" EXACT [KEGG_COMPOUND] synonym: "actinomycins" RELATED [ChEBI] xref: CAS:1402-38-6 {source="KEGG COMPOUND"} xref: CAS:1402-38-6 {source="ChemIDplus"} xref: KEGG:C01775 is_a: CHEBI:23239 ! chromopeptide [Term] id: CHEBI:15378 name: hydron namespace: chebi_ontology alt_id: CHEBI:10744 alt_id: CHEBI:13357 alt_id: CHEBI:5584 def: "The general name for the hydrogen nucleus, to be used without regard to the hydrogen nuclear mass (either for hydrogen in its natural abundance or where it is not desired to distinguish between the isotopes)." [] subset: 3_STAR synonym: "H(+)" RELATED [UniProt] synonym: "H+" RELATED [KEGG_COMPOUND] synonym: "hydrogen(1+)" EXACT IUPAC_NAME [IUPAC] synonym: "Hydron" EXACT [KEGG_COMPOUND] synonym: "hydron" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00080 is_a: CHEBI:25414 ! monoatomic monocation is_a: CHEBI:33251 ! monoatomic hydrogen is_a: CHEBI:33252 ! atomic nucleus is_a: CHEBI:60242 ! monovalent inorganic cation property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "GPRLSGONYQIRFK-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1.00794" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.008" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H+]" xsd:string [Term] id: CHEBI:15705 name: L-alpha-amino acid namespace: chebi_ontology alt_id: CHEBI:13072 alt_id: CHEBI:13243 alt_id: CHEBI:13797 alt_id: CHEBI:21224 alt_id: CHEBI:6175 def: "Any alpha-amino acid having L-configuration at the alpha-carbon." [] subset: 3_STAR synonym: "L-2-Amino acid" RELATED [KEGG_COMPOUND] synonym: "L-alpha-amino acid" EXACT [IUPAC] synonym: "L-alpha-amino acids" EXACT IUPAC_NAME [IUPAC] synonym: "L-alpha-amino acids" RELATED [ChEBI] synonym: "L-Amino acid" RELATED [KEGG_COMPOUND] xref: KEGG:C00151 is_a: CHEBI:33704 ! alpha-amino acid relationship: is_conjugate_acid_of CHEBI:59814 ! L-alpha-amino acid anion relationship: is_tautomer_of CHEBI:59869 ! L-alpha-amino acid zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@@H]([*])C(O)=O" xsd:string [Term] id: CHEBI:15740 name: formate namespace: chebi_ontology alt_id: CHEBI:14276 alt_id: CHEBI:24081 def: "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." [] subset: 3_STAR synonym: "aminate" RELATED [ChEBI] synonym: "formate" EXACT IUPAC_NAME [IUPAC] synonym: "formate" EXACT [UniProt] synonym: "formiate" RELATED [ChEBI] synonym: "formic acid, ion(1-)" RELATED [ChemIDplus] synonym: "formylate" RELATED [ChEBI] synonym: "HCO2 anion" RELATED [NIST_Chemistry_WebBook] synonym: "hydrogen carboxylate" RELATED [ChEBI] synonym: "methanoate" RELATED [ChEBI] xref: Beilstein:1901205 {source="Beilstein"} xref: CAS:71-47-6 {source="ChemIDplus"} xref: CAS:71-47-6 {source="NIST Chemistry WebBook"} xref: Gmelin:1006 {source="Gmelin"} xref: HMDB:HMDB0000142 xref: KEGG:C00058 xref: MetaCyc:FORMATE xref: PMID:17190852 {source="Europe PMC"} xref: PMID:3946945 {source="Europe PMC"} xref: Reaxys:1901205 {source="Reaxys"} xref: UM-BBD_compID:c0106 {source="UM-BBD"} xref: Wikipedia:Formate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35757 ! monocarboxylic acid anion relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:30751 ! formic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01744" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99820" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C([O-])=O" xsd:string [Term] id: CHEBI:15778 name: N-acyl-D-amino acid namespace: chebi_ontology alt_id: CHEBI:12474 alt_id: CHEBI:21631 alt_id: CHEBI:7224 def: "Any N-acyl-amino acid in which the amino acid moiety has D configuration." [] subset: 3_STAR is_a: CHEBI:51569 ! N-acyl-amino acid is_a: CHEBI:83812 ! non-proteinogenic amino acid derivative relationship: is_conjugate_acid_of CHEBI:59876 ! N-acyl-D-alpha-amino acid anion relationship: is_enantiomer_of CHEBI:21644 ! N-acyl-L-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H3NO3R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "101.06080" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "101.01129" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(=O)[C@@H]([*])NC([*])=O" xsd:string [Term] id: CHEBI:15966 name: D-glutamic acid namespace: chebi_ontology alt_id: CHEBI:21023 alt_id: CHEBI:4183 def: "An optically active form of glutamic acid having D-configuration." [] subset: 3_STAR synonym: "(2R)-2-aminopentanedioic acid" EXACT IUPAC_NAME [IUPAC] synonym: "(R)-2-aminopentanedioic acid" RELATED [ChEBI] synonym: "D-2-Aminoglutaric acid" RELATED [KEGG_COMPOUND] synonym: "D-Glutamic acid" EXACT [KEGG_COMPOUND] synonym: "D-glutamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "D-Glutaminic acid" RELATED [KEGG_COMPOUND] synonym: "D-Glutaminsaeure" RELATED [ChEBI] synonym: "DGL" RELATED [PDBeChem] synonym: "glutamic acid D-form" RELATED [ChemIDplus] xref: Beilstein:1723800 {source="Beilstein"} xref: CAS:6893-26-1 {source="NIST Chemistry WebBook"} xref: CAS:6893-26-1 {source="ChemIDplus"} xref: CAS:6893-26-1 {source="KEGG COMPOUND"} xref: DrugBank:DB02517 xref: Gmelin:201189 {source="Gmelin"} xref: HMDB:HMDB0003339 xref: KEGG:C00217 xref: KNApSAcK:C00019577 xref: MetaCyc:D-GLT xref: PDBeChem:DGL xref: Reaxys:1723800 {source="Reaxys"} is_a: CHEBI:16733 ! D-alpha-amino acid is_a: CHEBI:18237 ! glutamic acid relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_acid_of CHEBI:29986 ! D-glutamate(1-) relationship: is_enantiomer_of CHEBI:16015 ! L-glutamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-GSVOUGTGSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "147.12930" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "147.05316" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@H](CCC(O)=O)C(O)=O" xsd:string [Term] id: CHEBI:15986 name: polynucleotide namespace: chebi_ontology alt_id: CHEBI:13672 alt_id: CHEBI:14859 alt_id: CHEBI:8312 def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." [] subset: 3_STAR synonym: "Polynucleotide" EXACT [KEGG_COMPOUND] synonym: "polynucleotides" RELATED [ChEBI] xref: KEGG:C00419 is_a: CHEBI:33695 ! information biomacromolecule is_a: CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_part CHEBI:50319 ! nucleotide residue property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C5H8O6PR)n.C10H17O10PR2" xsd:string [Term] id: CHEBI:16015 name: L-glutamic acid namespace: chebi_ontology alt_id: CHEBI:21304 alt_id: CHEBI:42825 alt_id: CHEBI:6224 def: "An optically active form of glutamic acid having L-configuration." [] subset: 3_STAR synonym: "(2S)-2-aminopentanedioic acid" EXACT IUPAC_NAME [IUPAC] synonym: "(S)-2-aminopentanedioic acid" RELATED [ChEBI] synonym: "(S)-glutamic acid" RELATED [NIST_Chemistry_WebBook] synonym: "acide glutamique" RELATED INN [ChEBI] synonym: "acido glutamico" RELATED INN [ChEBI] synonym: "acidum glutamicum" RELATED INN [ChEBI] synonym: "E" RELATED [ChEBI] synonym: "Glu" RELATED [ChEBI] synonym: "Glutamate" RELATED [KEGG_COMPOUND] synonym: "GLUTAMIC ACID" RELATED [PDBeChem] synonym: "glutamic acid" RELATED INN [ChEBI] synonym: "L-Glu" RELATED [ChEBI] synonym: "L-Glutamic acid" EXACT [KEGG_COMPOUND] synonym: "L-glutamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "L-Glutaminic acid" RELATED [KEGG_COMPOUND] synonym: "L-Glutaminsaeure" RELATED [ChEBI] xref: Beilstein:1723801 {source="Beilstein"} xref: BPDB:2297 xref: CAS:56-86-0 {source="NIST Chemistry WebBook"} xref: CAS:56-86-0 {source="ChemIDplus"} xref: CAS:56-86-0 {source="KEGG COMPOUND"} xref: Drug_Central:1310 {source="DrugCentral"} xref: DrugBank:DB00142 xref: Gmelin:3502 {source="Gmelin"} xref: HMDB:HMDB0000148 xref: KEGG:C00025 xref: KEGG:D00007 xref: KNApSAcK:C00001358 xref: LINCS:LSM-36375 xref: MetaCyc:GLT xref: PDBeChem:GLU_LFOH xref: PMID:15739367 {source="Europe PMC"} xref: PMID:15930465 {source="Europe PMC"} xref: PMID:16719819 {source="Europe PMC"} xref: PMID:16892196 {source="Europe PMC"} xref: PMID:19581495 {source="Europe PMC"} xref: PMID:22219301 {source="Europe PMC"} xref: PMID:22735334 {source="Europe PMC"} xref: Reaxys:1723801 {source="Reaxys"} xref: Wikipedia:L-Glutamic_Acid is_a: CHEBI:18237 ! glutamic acid is_a: CHEBI:24318 ! glutamine family amino acid relationship: has_role CHEBI:173085 ! ferroptosis inducer relationship: has_role CHEBI:25512 ! neurotransmitter relationship: has_role CHEBI:27027 ! micronutrient relationship: has_role CHEBI:50733 ! nutraceutical relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_acid_of CHEBI:29985 ! L-glutamate(1-) relationship: is_enantiomer_of CHEBI:15966 ! D-glutamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-VKHMYHEASA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "147.12930" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "147.05316" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@@H](CCC(O)=O)C(O)=O" xsd:string [Term] id: CHEBI:16042 name: halide anion namespace: chebi_ontology alt_id: CHEBI:14384 alt_id: CHEBI:5605 def: "A monoatomic monoanion resulting from the addition of an electron to any halogen atom." [] subset: 3_STAR synonym: "a halide anion" RELATED [UniProt] synonym: "Halide" RELATED [KEGG_COMPOUND] synonym: "halide anions" RELATED [ChEBI] synonym: "halide ions" EXACT IUPAC_NAME [IUPAC] synonym: "halide(1-)" RELATED [ChEBI] synonym: "halides" RELATED [ChEBI] synonym: "halogen anion" RELATED [ChEBI] synonym: "HX" RELATED [KEGG_COMPOUND] xref: KEGG:C00462 is_a: CHEBI:33429 ! monoatomic monoanion is_a: CHEBI:79389 ! monovalent inorganic anion property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "X" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*-]" xsd:string [Term] id: CHEBI:16134 name: ammonia namespace: chebi_ontology alt_id: CHEBI:13405 alt_id: CHEBI:13406 alt_id: CHEBI:13407 alt_id: CHEBI:13771 alt_id: CHEBI:22533 alt_id: CHEBI:44269 alt_id: CHEBI:44284 alt_id: CHEBI:44404 alt_id: CHEBI:7434 def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." [] subset: 3_STAR synonym: "[NH3]" RELATED [MolBase] synonym: "AMMONIA" EXACT [PDBeChem] synonym: "Ammonia" EXACT [KEGG_COMPOUND] synonym: "ammonia" EXACT IUPAC_NAME [IUPAC] synonym: "ammoniac" RELATED [ChEBI] synonym: "Ammoniak" RELATED [ChemIDplus] synonym: "amoniaco" RELATED [ChEBI] synonym: "azane" EXACT IUPAC_NAME [IUPAC] synonym: "NH3" RELATED [KEGG_COMPOUND] synonym: "NH3" RELATED [UniProt] synonym: "NH3" RELATED [IUPAC] synonym: "R-717" RELATED [ChEBI] synonym: "spirit of hartshorn" RELATED [ChemIDplus] xref: Beilstein:3587154 {source="Beilstein"} xref: CAS:7664-41-7 {source="ChemIDplus"} xref: CAS:7664-41-7 {source="NIST Chemistry WebBook"} xref: CAS:7664-41-7 {source="KEGG COMPOUND"} xref: Drug_Central:4625 {source="DrugCentral"} xref: Gmelin:79 {source="Gmelin"} xref: HMDB:HMDB0000051 xref: KEGG:C00014 xref: KEGG:D02916 xref: KNApSAcK:C00007267 xref: MetaCyc:AMMONIA xref: MolBase:930 xref: PDBeChem:NH3 xref: PMID:110589 {source="Europe PMC"} xref: PMID:11139349 {source="Europe PMC"} xref: PMID:11540049 {source="Europe PMC"} xref: PMID:11746427 {source="Europe PMC"} xref: PMID:11783653 {source="Europe PMC"} xref: PMID:13753780 {source="Europe PMC"} xref: PMID:14663195 {source="Europe PMC"} xref: PMID:15092448 {source="Europe PMC"} xref: PMID:15094021 {source="Europe PMC"} xref: PMID:15554424 {source="Europe PMC"} xref: PMID:15969015 {source="Europe PMC"} xref: PMID:16008360 {source="Europe PMC"} xref: PMID:16050680 {source="Europe PMC"} xref: PMID:16348008 {source="Europe PMC"} xref: PMID:16349403 {source="Europe PMC"} xref: PMID:16614889 {source="Europe PMC"} xref: PMID:16664306 {source="Europe PMC"} xref: PMID:16842901 {source="Europe PMC"} xref: PMID:17025297 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17569513 {source="Europe PMC"} xref: PMID:17737668 {source="Europe PMC"} xref: PMID:18670398 {source="Europe PMC"} xref: PMID:22002069 {source="Europe PMC"} xref: PMID:22081570 {source="Europe PMC"} xref: PMID:22088435 {source="Europe PMC"} xref: PMID:22100291 {source="Europe PMC"} xref: PMID:22130175 {source="Europe PMC"} xref: PMID:22150211 {source="Europe PMC"} xref: PMID:22240068 {source="Europe PMC"} xref: PMID:22290316 {source="Europe PMC"} xref: PMID:22342082 {source="Europe PMC"} xref: PMID:22385337 {source="Europe PMC"} xref: PMID:22443779 {source="Europe PMC"} xref: PMID:22560242 {source="Europe PMC"} xref: Reaxys:3587154 {source="Reaxys"} xref: Wikipedia:Ammonia is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:35107 ! azane is_a: CHEBI:37176 ! mononuclear parent hydride is_a: FBcv:0000551 ! enzyme inhibitor relationship: has_role CHEBI:25212 ! metabolite relationship: has_role CHEBI:50910 ! neurotoxin relationship: has_role CHEBI:59740 ! nucleophilic reagent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77941 ! EC 3.5.1.4 (amidase) inhibitor relationship: has_role CHEBI:78433 ! refrigerant relationship: is_conjugate_acid_of CHEBI:29337 ! azanide relationship: is_conjugate_base_of CHEBI:28938 ! ammonium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.03056" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]N([H])[H]" xsd:string [Term] id: CHEBI:16189 name: sulfate namespace: chebi_ontology alt_id: CHEBI:15135 alt_id: CHEBI:45687 alt_id: CHEBI:9335 def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." [] subset: 3_STAR synonym: "[SO4](2-)" RELATED [IUPAC] synonym: "SO4(2-)" RELATED [IUPAC] synonym: "Sulfate" EXACT [KEGG_COMPOUND] synonym: "sulfate" EXACT [UniProt] synonym: "sulfate" EXACT IUPAC_NAME [IUPAC] synonym: "Sulfate anion(2-)" RELATED [HMDB] synonym: "Sulfate dianion" RELATED [HMDB] synonym: "SULFATE ION" RELATED [PDBeChem] synonym: "Sulfate(2-)" RELATED [HMDB] synonym: "Sulfuric acid ion(2-)" RELATED [HMDB] synonym: "sulphate" RELATED [ChEBI] synonym: "sulphate ion" RELATED [ChEBI] synonym: "tetraoxidosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3648446 {source="Beilstein"} xref: CAS:14808-79-8 {source="ChemIDplus"} xref: CAS:14808-79-8 {source="NIST Chemistry WebBook"} xref: Gmelin:2120 {source="Gmelin"} xref: HMDB:HMDB0001448 xref: KEGG:C00059 xref: KEGG:D05963 xref: MetaCyc:SULFATE xref: PDBeChem:SO4 xref: PMID:11200094 {source="Europe PMC"} xref: PMID:11452993 {source="Europe PMC"} xref: PMID:11581495 {source="Europe PMC"} xref: PMID:11798107 {source="Europe PMC"} xref: PMID:12166931 {source="Europe PMC"} xref: PMID:12668033 {source="Europe PMC"} xref: PMID:14597181 {source="Europe PMC"} xref: PMID:15093386 {source="Europe PMC"} xref: PMID:15984785 {source="Europe PMC"} xref: PMID:16186560 {source="Europe PMC"} xref: PMID:16345535 {source="Europe PMC"} xref: PMID:16347366 {source="Europe PMC"} xref: PMID:16348007 {source="Europe PMC"} xref: PMID:16483812 {source="Europe PMC"} xref: PMID:16534979 {source="Europe PMC"} xref: PMID:16656509 {source="Europe PMC"} xref: PMID:16742508 {source="Europe PMC"} xref: PMID:16742518 {source="Europe PMC"} xref: PMID:17120760 {source="Europe PMC"} xref: PMID:17420092 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17709180 {source="Europe PMC"} xref: PMID:18398178 {source="Europe PMC"} xref: PMID:18815700 {source="Europe PMC"} xref: PMID:18846414 {source="Europe PMC"} xref: PMID:19047345 {source="Europe PMC"} xref: PMID:19244483 {source="Europe PMC"} xref: PMID:19544990 {source="Europe PMC"} xref: PMID:19628332 {source="Europe PMC"} xref: PMID:19812358 {source="Europe PMC"} xref: PMID:30398859 {source="Europe PMC"} xref: Reaxys:3648446 {source="Reaxys"} xref: Wikipedia:Sulfate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33482 ! sulfur oxoanion is_a: CHEBI:48154 ! sulfur oxide is_a: CHEBI:79388 ! divalent inorganic anion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:45696 ! hydrogensulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06360" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95283" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S([O-])(=O)=O" xsd:string [Term] id: CHEBI:16199 name: urea namespace: chebi_ontology alt_id: CHEBI:15292 alt_id: CHEBI:27218 alt_id: CHEBI:46379 alt_id: CHEBI:9888 def: "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." [] subset: 3_STAR synonym: "1728" RELATED [PPDB] synonym: "Carbamide" RELATED [KEGG_COMPOUND] synonym: "carbamide" RELATED INN [ChEBI] synonym: "carbonyldiamide" RELATED [NIST_Chemistry_WebBook] synonym: "E927b" RELATED [ChEBI] synonym: "H2NC(O)NH2" RELATED [ChEBI] synonym: "Harnstoff" RELATED [NIST_Chemistry_WebBook] synonym: "Karbamid" RELATED [ChEBI] synonym: "ur" RELATED [IUPAC] synonym: "UREA" EXACT [PDBeChem] synonym: "Urea" EXACT [KEGG_COMPOUND] synonym: "urea" EXACT [UniProt] synonym: "urea" EXACT IUPAC_NAME [IUPAC] synonym: "uree" RELATED [ChEBI] xref: Beilstein:635724 {source="Beilstein"} xref: CAS:57-13-6 {source="ChemIDplus"} xref: CAS:57-13-6 {source="NIST Chemistry WebBook"} xref: CAS:57-13-6 {source="KEGG COMPOUND"} xref: Drug_Central:4264 {source="DrugCentral"} xref: DrugBank:DB03904 xref: ECMDB:ECMDB04172 xref: Gmelin:1378 {source="Gmelin"} xref: HMDB:HMDB0000294 xref: KEGG:C00086 xref: KEGG:D00023 xref: KNApSAcK:C00007314 xref: MetaCyc:UREA xref: PDBeChem:URE xref: PMID:18037357 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PPDB:1728 xref: Reaxys:635724 {source="Reaxys"} xref: UM-BBD_compID:c0165 {source="UM-BBD"} xref: Wikipedia:Urea xref: YMDB:YMDB00003 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:29347 ! monocarboxylic acid amide is_a: CHEBI:64708 ! one-carbon compound relationship: has_functional_parent CHEBI:28976 ! carbonic acid relationship: has_role CHEBI:33287 ! fertilizer relationship: has_role CHEBI:64577 ! flour treatment agent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:83056 ! Daphnia magna metabolite relationship: is_tautomer_of CHEBI:48376 ! carbamimidic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH4N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XSQUKJJJFZCRTK-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.05534" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.03236" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(N)=O" xsd:string [Term] id: CHEBI:16235 name: guanine namespace: chebi_ontology alt_id: CHEBI:14371 alt_id: CHEBI:14372 alt_id: CHEBI:24443 alt_id: CHEBI:42948 alt_id: CHEBI:5563 def: "A 2-aminopurine carrying a 6-oxo substituent." [] subset: 3_STAR synonym: "2-amino-1,9-dihydro-6H-purin-6-one" EXACT IUPAC_NAME [IUPAC] synonym: "2-Amino-6-hydroxypurine" RELATED [KEGG_COMPOUND] synonym: "2-amino-6-oxopurine" RELATED [ChEBI] synonym: "G" RELATED [ChEBI] synonym: "Gua" RELATED [CBN] synonym: "GUANINE" EXACT [PDBeChem] synonym: "Guanine" EXACT [KEGG_COMPOUND] synonym: "guanine" EXACT [UniProt] xref: Beilstein:147911 {source="Beilstein"} xref: CAS:73-40-5 {source="NIST Chemistry WebBook"} xref: CAS:73-40-5 {source="ChemIDplus"} xref: CAS:73-40-5 {source="KEGG COMPOUND"} xref: DrugBank:DB02377 xref: Gmelin:431879 {source="Gmelin"} xref: HMDB:HMDB0000132 xref: KEGG:C00242 xref: KNApSAcK:C00001501 xref: MetaCyc:GUANINE xref: PDBeChem:GUN xref: PMID:22770225 {source="Europe PMC"} xref: PMID:8070089 {source="Europe PMC"} xref: Reaxys:147911 {source="Reaxys"} xref: Wikipedia:Guanine is_a: BFO:0000004 ! independent continuant is_a: CHEBI:20702 ! 2-aminopurines is_a: CHEBI:25810 ! oxopurine is_a: CHEBI:26386 ! purine nucleobase relationship: has_parent_hydride CHEBI:35589 ! 9H-purine relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:84735 ! algal metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H5N5O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UYTPUPDQBNUYGX-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "151.126" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "151.04941" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12=C(N=C(NC1=O)N)NC=N2" xsd:string [Term] id: CHEBI:16385 name: organic sulfide namespace: chebi_ontology alt_id: CHEBI:13694 alt_id: CHEBI:26960 alt_id: CHEBI:9340 def: "Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers." [] subset: 3_STAR synonym: "organic sulfides" RELATED [ChEBI] synonym: "RSR" RELATED [IUPAC] synonym: "Sulfide" RELATED [KEGG_COMPOUND] synonym: "sulfides" EXACT IUPAC_NAME [IUPAC] synonym: "Thioether" RELATED [KEGG_COMPOUND] synonym: "thioethers" RELATED [IUPAC] xref: KEGG:C00297 is_a: CHEBI:26822 ! sulfide is_a: CHEBI:33261 ! organosulfur compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "SR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "32.066" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.97207" xsd:string [Term] id: CHEBI:16482 name: naphthalene namespace: chebi_ontology alt_id: CHEBI:14638 alt_id: CHEBI:25469 alt_id: CHEBI:44619 alt_id: CHEBI:7472 def: "An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia." [] subset: 3_STAR synonym: "naftaleno" RELATED [ChEBI] synonym: "naftalina" RELATED [ChEBI] synonym: "naphtalene" RELATED [ChEBI] synonym: "naphtaline" RELATED [ChEBI] synonym: "Naphthalen" RELATED [ChEBI] synonym: "NAPHTHALENE" EXACT [PDBeChem] synonym: "Naphthalene" EXACT [KEGG_COMPOUND] synonym: "naphthalene" EXACT [UniProt] synonym: "naphthalene" EXACT IUPAC_NAME [IUPAC] synonym: "Naphthalin" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1421310 {source="Beilstein"} xref: CAS:91-20-3 {source="ChemIDplus"} xref: CAS:91-20-3 {source="KEGG COMPOUND"} xref: CAS:91-20-3 {source="NIST Chemistry WebBook"} xref: Gmelin:3347 {source="Gmelin"} xref: HMDB:HMDB0029751 xref: KEGG:C00829 xref: KNApSAcK:C00001259 xref: MetaCyc:NAPHTHALENE xref: PDBeChem:NPY xref: PMID:10814889 {source="Europe PMC"} xref: PMID:11202734 {source="Europe PMC"} xref: PMID:16220979 {source="Europe PMC"} xref: PMID:16699520 {source="Europe PMC"} xref: PMID:17850896 {source="Europe PMC"} xref: PMID:26875834 {source="Europe PMC"} xref: PMID:26895256 {source="Europe PMC"} xref: PMID:27439360 {source="Europe PMC"} xref: PPDB:1312 xref: Reaxys:1421310 {source="Reaxys"} xref: UM-BBD_compID:c0333 {source="UM-BBD"} xref: Wikipedia:Naphthalene is_a: CHEBI:25477 ! naphthalenes is_a: CHEBI:35426 ! ortho-fused bicyclic arene relationship: has_role CHEBI:27311 ! volatile oil component relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:68494 ! apoptosis inhibitor relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:78298 ! environmental contaminant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H8" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UFWIBTONFRDIAS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "128.17052" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "128.06260" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ccc2ccccc2c1" xsd:string [Term] id: CHEBI:16509 name: 1,4-benzoquinone namespace: chebi_ontology alt_id: CHEBI:12837 alt_id: CHEBI:15009 alt_id: CHEBI:18927 alt_id: CHEBI:49820 alt_id: CHEBI:8730 def: "The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene." [] subset: 3_STAR synonym: "1,4-Benzochinon" RELATED [ChEBI] synonym: "1,4-Benzoquinone" EXACT [KEGG_COMPOUND] synonym: "1,4-benzoquinone" EXACT [UniProt] synonym: "1,4-benzoquinone" EXACT [NIST_Chemistry_WebBook] synonym: "2,5-Cyclohexadiene-1,4-dione" RELATED [KEGG_COMPOUND] synonym: "benzo-1,4-quinone" RELATED [NIST_Chemistry_WebBook] synonym: "benzoquinone" RELATED [ChemIDplus] synonym: "cyclohexa-2,5-diene-1,4-dione" EXACT IUPAC_NAME [IUPAC] synonym: "p-Benzoquinone" RELATED [KEGG_COMPOUND] synonym: "p-Chinon" RELATED [NIST_Chemistry_WebBook] synonym: "p-quinone" RELATED [HMDB] synonym: "para-benzoquinone" RELATED [HMDB] synonym: "Quinone" RELATED [KEGG_COMPOUND] xref: Beilstein:773967 {source="Beilstein"} xref: CAS:106-51-4 {source="NIST Chemistry WebBook"} xref: CAS:106-51-4 {source="ChemIDplus"} xref: CAS:106-51-4 {source="KEGG COMPOUND"} xref: Gmelin:2741 {source="Gmelin"} xref: HMDB:HMDB0003364 xref: KEGG:C00472 xref: KEGG:C15602 xref: MetaCyc:P-BENZOQUINONE xref: PDBeChem:PLQ xref: PMID:10462055 {source="Europe PMC"} xref: PMID:11304127 {source="Europe PMC"} xref: PMID:1395635 {source="Europe PMC"} xref: PMID:15182198 {source="Europe PMC"} xref: PMID:15618234 {source="Europe PMC"} xref: PMID:15920754 {source="Europe PMC"} xref: PMID:16484134 {source="Europe PMC"} xref: PMID:24023812 {source="Europe PMC"} xref: PMID:25057895 {source="Europe PMC"} xref: PMID:9118901 {source="Europe PMC"} xref: Reaxys:773967 {source="Reaxys"} xref: UM-BBD_compID:c0261 {source="UM-BBD"} xref: Wikipedia:1\,4-Benzoquinone is_a: BFO:0000004 ! independent continuant is_a: CHEBI:132124 ! 1,4-benzoquinones relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76967 ! human xenobiotic metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H4O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "AZQWKYJCGOJGHM-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "108.09480" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "108.02113" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C1C=CC(=O)C=C1" xsd:string [Term] id: CHEBI:16646 name: carbohydrate namespace: chebi_ontology alt_id: CHEBI:15131 alt_id: CHEBI:23008 alt_id: CHEBI:9318 def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." [] subset: 3_STAR synonym: "carbohidrato" RELATED [IUPAC] synonym: "carbohidratos" RELATED [IUPAC] synonym: "carbohydrate" EXACT IUPAC_NAME [IUPAC] synonym: "carbohydrates" EXACT IUPAC_NAME [IUPAC] synonym: "glucide" RELATED [ChEBI] synonym: "glucides" RELATED [ChEBI] synonym: "glucido" RELATED [ChEBI] synonym: "glucidos" RELATED [ChEBI] synonym: "hydrates de carbone" RELATED [ChEBI] synonym: "Kohlenhydrat" RELATED [ChEBI] synonym: "Kohlenhydrate" RELATED [ChEBI] synonym: "saccharide" RELATED [IUPAC] synonym: "saccharides" RELATED [IUPAC] synonym: "saccharidum" RELATED [ChEBI] xref: Wikipedia:Carbohydrate is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16670 name: peptide namespace: chebi_ontology alt_id: CHEBI:14753 alt_id: CHEBI:25906 alt_id: CHEBI:7990 def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." [] subset: 3_STAR synonym: "Peptid" RELATED [ChEBI] synonym: "Peptide" EXACT [KEGG_COMPOUND] synonym: "peptides" EXACT IUPAC_NAME [IUPAC] synonym: "peptido" RELATED [ChEBI] synonym: "peptidos" RELATED [ChEBI] xref: KEGG:C00012 is_a: CHEBI:37622 ! carboxamide is_a: CHEBI:50047 ! organic amino compound relationship: has_part CHEBI:33708 ! amino-acid residue relationship: is_tautomer_of CHEBI:60466 ! peptide zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C2H2NOR)nC2H3NOR" xsd:string [Term] id: CHEBI:16716 name: benzene namespace: chebi_ontology alt_id: CHEBI:13876 alt_id: CHEBI:22703 alt_id: CHEBI:3025 alt_id: CHEBI:41187 def: "A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system." [] subset: 3_STAR synonym: "[6]annulene" RELATED [NIST_Chemistry_WebBook] synonym: "Benzen" RELATED [IUPAC] synonym: "BENZENE" EXACT [PDBeChem] synonym: "Benzene" EXACT [KEGG_COMPOUND] synonym: "benzene" EXACT IUPAC_NAME [IUPAC] synonym: "benzene" EXACT [UniProt] synonym: "benzene" EXACT [ChEBI] synonym: "Benzine" RELATED [UM-BBD] synonym: "Benzol" RELATED [ChemIDplus] synonym: "benzole" RELATED [NIST_Chemistry_WebBook] synonym: "Bicarburet of hydrogen" RELATED [ChemIDplus] synonym: "Coal naphtha" RELATED [ChemIDplus] synonym: "cyclohexatriene" RELATED [UM-BBD] synonym: "Mineral naphtha" RELATED [ChemIDplus] synonym: "Phene" RELATED [ChemIDplus] synonym: "phenyl hydride" RELATED [UM-BBD] synonym: "Pyrobenzol" RELATED [ChemIDplus] synonym: "Pyrobenzole" RELATED [ChemIDplus] xref: Beilstein:969212 {source="Beilstein"} xref: CAS:71-43-2 {source="ChemIDplus"} xref: CAS:71-43-2 {source="NIST Chemistry WebBook"} xref: CAS:71-43-2 {source="KEGG COMPOUND"} xref: Gmelin:1671 {source="Gmelin"} xref: HMDB:HMDB0001505 xref: KEGG:C01407 xref: PDBeChem:BNZ xref: PMID:11684179 {source="Europe PMC"} xref: PMID:11993966 {source="Europe PMC"} xref: PMID:12857942 {source="Europe PMC"} xref: PMID:14677922 {source="Europe PMC"} xref: PMID:15468289 {source="Europe PMC"} xref: PMID:15935818 {source="Europe PMC"} xref: PMID:16161967 {source="Europe PMC"} xref: PMID:17373369 {source="Europe PMC"} xref: PMID:18072742 {source="Europe PMC"} xref: PMID:18407866 {source="Europe PMC"} xref: PMID:18409691 {source="Europe PMC"} xref: PMID:18836923 {source="Europe PMC"} xref: PMID:19228219 {source="Europe PMC"} xref: PMID:21325737 {source="Europe PMC"} xref: PMID:23088855 {source="Europe PMC"} xref: PMID:23222815 {source="Europe PMC"} xref: PMID:23534829 {source="Europe PMC"} xref: PMID:6353911 {source="Europe PMC"} xref: PMID:8124204 {source="Europe PMC"} xref: Reaxys:969212 {source="Reaxys"} xref: UM-BBD_compID:c0142 {source="UM-BBD"} xref: Wikipedia:Benzene is_a: BFO:0000004 ! independent continuant is_a: CHEBI:134179 ! volatile organic compound is_a: CHEBI:22712 ! benzenes is_a: CHEBI:33842 ! aromatic annulene relationship: has_role CHEBI:48355 ! non-polar solvent relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:78298 ! environmental contaminant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UHOVQNZJYSORNB-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "78.11184" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "78.04695" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ccccc1" xsd:string [Term] id: CHEBI:16733 name: D-alpha-amino acid namespace: chebi_ontology alt_id: CHEBI:12909 alt_id: CHEBI:13625 alt_id: CHEBI:20906 alt_id: CHEBI:4097 subset: 3_STAR synonym: "D-alpha-amino acid" EXACT [ChEBI] synonym: "D-alpha-amino acids" EXACT IUPAC_NAME [IUPAC] synonym: "D-alpha-amino acids" RELATED [ChEBI] synonym: "D-Amino acid" RELATED [KEGG_COMPOUND] xref: KEGG:C00405 is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid relationship: is_conjugate_acid_of CHEBI:60895 ! D-alpha-amino acid anion relationship: is_tautomer_of CHEBI:59871 ! D-alpha-amino acid zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@H]([*])C(O)=O" xsd:string [Term] id: CHEBI:167559 name: glycan namespace: chebi_ontology def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." [] subset: 3_STAR synonym: "glycans" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16842 name: formaldehyde namespace: chebi_ontology alt_id: CHEBI:14274 alt_id: CHEBI:24077 alt_id: CHEBI:337763 alt_id: CHEBI:5142 def: "An aldehyde resulting from the formal oxidation of methanol." [] subset: 3_STAR synonym: "Formaldehyd" RELATED [NIST_Chemistry_WebBook] synonym: "FORMALDEHYDE" EXACT [PDBeChem] synonym: "Formaldehyde" EXACT [KEGG_COMPOUND] synonym: "formaldehyde" EXACT [UniProt] synonym: "formaldehyde" EXACT IUPAC_NAME [IUPAC] synonym: "FORMALIN" RELATED [ChEMBL] synonym: "Formalin" RELATED [KEGG_COMPOUND] synonym: "Methanal" RELATED [KEGG_COMPOUND] synonym: "Methylene oxide" RELATED [KEGG_COMPOUND] synonym: "Oxomethane" RELATED [KEGG_COMPOUND] synonym: "Oxomethylene" RELATED [KEGG_COMPOUND] xref: Beilstein:1209228 {source="Beilstein"} xref: CAS:50-00-0 {source="NIST Chemistry WebBook"} xref: CAS:50-00-0 {source="ChemIDplus"} xref: CAS:50-00-0 {source="KEGG COMPOUND"} xref: Drug_Central:3244 {source="DrugCentral"} xref: DrugBank:DB03843 xref: Gmelin:445 {source="Gmelin"} xref: HMDB:HMDB0001426 xref: KEGG:C00067 xref: KEGG:D00017 xref: MetaCyc:FORMALDEHYDE xref: PDBeChem:FOR xref: PMID:110589 {source="Europe PMC"} xref: PMID:12686735 {source="Europe PMC"} xref: PMID:15091529 {source="Europe PMC"} xref: PMID:16423181 {source="Europe PMC"} xref: PMID:17618393 {source="Europe PMC"} xref: PMID:18837732 {source="Europe PMC"} xref: PMID:25042713 {source="Europe PMC"} xref: PMID:7381846 {source="ChEMBL"} xref: PMID:7548723 {source="Europe PMC"} xref: PMID:7689168 {source="Europe PMC"} xref: PMID:7896413 {source="Europe PMC"} xref: PMID:9686972 {source="Europe PMC"} xref: PPDB:359 xref: Reaxys:1209228 {source="Reaxys"} xref: UM-BBD_compID:c0122 {source="UM-BBD"} xref: Wikipedia:Formaldehyde is_a: CHEBI:17478 ! aldehyde is_a: CHEBI:64708 ! one-carbon compound is_a: FBcv:0000551 ! enzyme inhibitor is_a: FBcv:0000584 ! formaldehyde equivalent_to: FBcv:0000584 ! formaldehyde relationship: has_role CHEBI:48219 ! disinfectant relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:50904 ! allergen relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77941 ! EC 3.5.1.4 (amidase) inhibitor relationship: has_role CHEBI:78298 ! environmental contaminant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O/c1-2/h1H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WSFSSNUMVMOOMR-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "30.02598" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "30.01056" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C([H])=O" xsd:string [Term] id: CHEBI:16991 name: deoxyribonucleic acid namespace: chebi_ontology alt_id: CHEBI:13302 alt_id: CHEBI:21123 alt_id: CHEBI:33698 alt_id: CHEBI:4291 def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." [] subset: 3_STAR synonym: "(Deoxyribonucleotide)m" RELATED [KEGG_COMPOUND] synonym: "(Deoxyribonucleotide)n" RELATED [KEGG_COMPOUND] synonym: "(Deoxyribonucleotide)n+m" RELATED [KEGG_COMPOUND] synonym: "Deoxyribonucleic acid" EXACT [KEGG_COMPOUND] synonym: "deoxyribonucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "deoxyribonucleic acids" RELATED [ChEBI] synonym: "Desoxyribonukleinsaeure" RELATED [ChEBI] synonym: "desoxyribose nucleic acid" RELATED [ChemIDplus] synonym: "DNA" RELATED [KEGG_COMPOUND] synonym: "DNA" RELATED [IUPAC] synonym: "DNAn" RELATED [KEGG_COMPOUND] synonym: "DNAn+1" RELATED [KEGG_COMPOUND] synonym: "DNS" RELATED [ChEBI] synonym: "thymus nucleic acid" RELATED [ChEBI] xref: CAS:9007-49-2 {source="ChemIDplus"} xref: CAS:9007-49-2 {source="KEGG COMPOUND"} xref: KEGG:C00039 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33696 ! nucleic acid is_a: FBcv:0000579 ! DNA equivalent_to: FBcv:0000579 ! DNA relationship: has_part CHEBI:33793 ! canonical deoxyribonucleoside residue relationship: has_part CHEBI:50298 ! canonical deoxyribonucleotide residue relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite [Term] id: CHEBI:16998 name: D-phenylalanine namespace: chebi_ontology alt_id: CHEBI:13007 alt_id: CHEBI:21067 alt_id: CHEBI:42207 alt_id: CHEBI:4224 def: "The D-enantiomer of phenylalanine." [] subset: 3_STAR synonym: "(2R)-2-amino-3-phenylpropanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "D-alpha-Amino-beta-phenylpropionic acid" RELATED [KEGG_COMPOUND] synonym: "D-Phe" RELATED [ChEBI] synonym: "D-PHENYLALANINE" EXACT [PDBeChem] synonym: "D-Phenylalanine" EXACT [KEGG_COMPOUND] synonym: "D-phenylalanine" EXACT IUPAC_NAME [IUPAC] synonym: "DPN" RELATED [PDBeChem] synonym: "phenylalanine D-form" RELATED [ChemIDplus] xref: Beilstein:2804068 {source="Beilstein"} xref: CAS:673-06-3 {source="KEGG COMPOUND"} xref: CAS:673-06-3 {source="ChemIDplus"} xref: DrugBank:DB02556 xref: ECMDB:ECMDB20144 xref: Gmelin:83219 {source="Gmelin"} xref: KEGG:C02265 xref: MetaCyc:CPD-216 xref: PDBeChem:DPN xref: PMID:22382026 {source="Europe PMC"} xref: PMID:22397264 {source="Europe PMC"} xref: PMID:24464217 {source="Europe PMC"} xref: PMID:7114516 {source="Europe PMC"} xref: Reaxys:2804068 {source="Reaxys"} xref: YMDB:YMDB00995 is_a: CHEBI:16733 ! D-alpha-amino acid is_a: CHEBI:28044 ! phenylalanine relationship: is_conjugate_acid_of CHEBI:32494 ! D-phenylalaninate relationship: is_conjugate_base_of CHEBI:32495 ! D-phenylalaninium relationship: is_enantiomer_of CHEBI:17295 ! L-phenylalanine relationship: is_tautomer_of CHEBI:57981 ! D-phenylalanine zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H11NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-MRVPVSSYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "165.18918" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "165.07898" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@H](Cc1ccccc1)C(O)=O" xsd:string [Term] id: CHEBI:17051 name: fluoride namespace: chebi_ontology alt_id: CHEBI:14271 alt_id: CHEBI:49593 alt_id: CHEBI:5113 subset: 3_STAR synonym: "F(-)" RELATED [IUPAC] synonym: "F-" RELATED [KEGG_COMPOUND] synonym: "Fluoride" EXACT [KEGG_COMPOUND] synonym: "fluoride" EXACT [UniProt] synonym: "fluoride" EXACT IUPAC_NAME [IUPAC] synonym: "FLUORIDE ION" RELATED [PDBeChem] synonym: "Fluoride ion" RELATED [KEGG_COMPOUND] synonym: "fluoride(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "Fluorine anion" RELATED [NIST_Chemistry_WebBook] xref: CAS:16984-48-8 {source="NIST Chemistry WebBook"} xref: CAS:16984-48-8 {source="ChemIDplus"} xref: Gmelin:14905 {source="Gmelin"} xref: KEGG:C00742 xref: PDBeChem:F is_a: CHEBI:16042 ! halide anion is_a: CHEBI:36895 ! monoatomic fluorine relationship: is_conjugate_base_of CHEBI:29228 ! hydrogen fluoride property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "F" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/FH/h1H/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KRHYYFGTRYWZRS-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "18.99840" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.99895" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[F-]" xsd:string [Term] id: CHEBI:17087 name: ketone namespace: chebi_ontology alt_id: CHEBI:13427 alt_id: CHEBI:13646 alt_id: CHEBI:24974 alt_id: CHEBI:6127 alt_id: CHEBI:8742 def: "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." [] subset: 3_STAR synonym: "a ketone" RELATED [UniProt] synonym: "cetone" RELATED [ChEBI] synonym: "Keton" RELATED [ChEBI] synonym: "Ketone" EXACT [KEGG_COMPOUND] synonym: "ketones" EXACT IUPAC_NAME [IUPAC] synonym: "ketones" RELATED [ChEBI] synonym: "R-CO-R'" RELATED [KEGG_COMPOUND] xref: KEGG:C01450 xref: Wikipedia:Ketone is_a: CHEBI:36586 ! carbonyl compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "COR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "28.010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C([*])=O" xsd:string [Term] id: CHEBI:17102 name: phosphoramide namespace: chebi_ontology alt_id: CHEBI:14827 alt_id: CHEBI:26076 alt_id: CHEBI:8162 def: "A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR2)3, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR2)2 , P(=O)(OH)2(NR2)." [] subset: 3_STAR synonym: "phosphamide" RELATED [ChEBI] synonym: "phosphamides" RELATED [ChEBI] synonym: "phosphoramides" RELATED [ChEBI] is_a: CHEBI:33256 ! primary amide relationship: has_functional_parent CHEBI:26078 ! phosphoric acid [Term] id: CHEBI:17137 name: hydrogensulfite namespace: chebi_ontology alt_id: CHEBI:13367 alt_id: CHEBI:5598 subset: 3_STAR synonym: "[SO2(OH)](-)" RELATED [IUPAC] synonym: "Bisulfite" RELATED [KEGG_COMPOUND] synonym: "bisulfite" RELATED [ChemIDplus] synonym: "bisulphite" RELATED [ChemIDplus] synonym: "HSO3(-)" RELATED [IUPAC] synonym: "HSO3-" RELATED [KEGG_COMPOUND] synonym: "Hydrogen sulfite" RELATED [KEGG_COMPOUND] synonym: "hydrogen sulfite(1-)" RELATED [ChemIDplus] synonym: "hydrogen(trioxidosulfate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogensulfite(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxosulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxosulfate(IV)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrosulfite anion" RELATED [ChemIDplus] synonym: "hydroxidodioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "monohydrogentrioxosulfate" EXACT IUPAC_NAME [IUPAC] xref: CAS:15181-46-1 {source="KEGG COMPOUND"} xref: CAS:15181-46-1 {source="ChemIDplus"} xref: Gmelin:1455 {source="Gmelin"} xref: KEGG:C11481 xref: PDBeChem:SO3 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33482 ! sulfur oxoanion relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:17359 ! sulfite relationship: is_conjugate_base_of CHEBI:48854 ! sulfurous acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "81.07214" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "80.96519" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OS([O-])=O" xsd:string [Term] id: CHEBI:172390 name: glycol ether namespace: chebi_ontology def: "A hydroxyether which contains both an ether and alcohol functional groups. It is one of the most versatile classes of organic solvents which are commonly used in paints, cleaners, adhesives, pharmaceuticals and cosmetics." [] subset: 3_STAR synonym: "glycol ethers" RELATED [ChEBI] xref: PMID:28650840 {source="Europe PMC"} xref: PMID:29536623 {source="Europe PMC"} xref: PMID:30471335 {source="Europe PMC"} xref: PMID:31518935 {source="Europe PMC"} xref: PMID:32172156 {source="Europe PMC"} xref: Wikipedia:Glycol_ethers is_a: BFO:0000004 ! independent continuant is_a: CHEBI:46789 ! hydroxyether relationship: has_functional_parent CHEBI:13643 ! glycol relationship: has_role CHEBI:48356 ! protic solvent [Term] id: CHEBI:17258 name: 7H-purine namespace: chebi_ontology alt_id: CHEBI:14968 alt_id: CHEBI:8639 def: "The 7H-tautomer of purine." [] subset: 3_STAR synonym: "7H-purine" EXACT IUPAC_NAME [IUPAC] synonym: "Purine" RELATED [KEGG_COMPOUND] synonym: "Purine base" RELATED [KEGG_COMPOUND] xref: Beilstein:3200 {source="Beilstein"} xref: Gmelin:601779 {source="Gmelin"} xref: HMDB:HMDB0001366 xref: KEGG:C15587 xref: Reaxys:3200 {source="Reaxys"} is_a: CHEBI:35584 ! purine relationship: is_tautomer_of CHEBI:35586 ! 1H-purine relationship: is_tautomer_of CHEBI:35588 ! 3H-purine relationship: is_tautomer_of CHEBI:35589 ! 9H-purine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H4N4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "120.11222" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "120.04360" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ncc2[nH]cnc2n1" xsd:string [Term] id: CHEBI:17295 name: L-phenylalanine namespace: chebi_ontology alt_id: CHEBI:13151 alt_id: CHEBI:21370 alt_id: CHEBI:44851 alt_id: CHEBI:44885 alt_id: CHEBI:45079 alt_id: CHEBI:6282 def: "The L-enantiomer of phenylalanine." [] subset: 3_STAR synonym: "(2S)-2-amino-3-phenylpropanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "(S)-2-Amino-3-phenylpropionic acid" RELATED [HMDB] synonym: "(S)-alpha-Amino-beta-phenylpropionic acid" RELATED [KEGG_COMPOUND] synonym: "3-phenyl-L-alanine" RELATED [NIST_Chemistry_WebBook] synonym: "beta-phenyl-L-alanine" RELATED [NIST_Chemistry_WebBook] synonym: "F" RELATED [ChEBI] synonym: "L-Phenylalanine" EXACT [KEGG_COMPOUND] synonym: "L-phenylalanine" EXACT IUPAC_NAME [IUPAC] synonym: "Phe" RELATED [ChEBI] synonym: "PHENYLALANINE" RELATED [PDBeChem] xref: Beilstein:1910408 {source="Beilstein"} xref: CAS:63-91-2 {source="KEGG COMPOUND"} xref: CAS:63-91-2 {source="NIST Chemistry WebBook"} xref: CAS:63-91-2 {source="ChemIDplus"} xref: Drug_Central:2144 {source="DrugCentral"} xref: DrugBank:DB00120 xref: ECMDB:ECMDB00159 xref: Gmelin:50837 {source="Gmelin"} xref: HMDB:HMDB0000159 xref: KEGG:C00079 xref: KEGG:D00021 xref: KNApSAcK:C00001386 xref: MetaCyc:PHE xref: PDBeChem:PHE xref: PMID:13945318 {source="Europe PMC"} xref: PMID:16893175 {source="Europe PMC"} xref: PMID:17784858 {source="Europe PMC"} xref: PMID:21203787 {source="Europe PMC"} xref: PMID:21956539 {source="Europe PMC"} xref: PMID:22081386 {source="Europe PMC"} xref: PMID:22112574 {source="Europe PMC"} xref: PMID:22143120 {source="Europe PMC"} xref: PMID:22209218 {source="Europe PMC"} xref: PMID:22494897 {source="Europe PMC"} xref: PMID:23836015 {source="Europe PMC"} xref: PMID:24464217 {source="Europe PMC"} xref: PMID:24733517 {source="Europe PMC"} xref: PMID:24966042 {source="Europe PMC"} xref: Reaxys:1910408 {source="Reaxys"} xref: Wikipedia:Phenylalanine xref: YMDB:YMDB00304 is_a: CHEBI:28044 ! phenylalanine is_a: CHEBI:73690 ! erythrose 4-phosphate/phosphoenolpyruvate family amino acid is_a: FBcv:0000551 ! enzyme inhibitor relationship: has_role CHEBI:27027 ! micronutrient relationship: has_role CHEBI:50733 ! nutraceutical relationship: has_role CHEBI:63332 ! EC 3.1.3.1 (alkaline phosphatase) inhibitor relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:76967 ! human xenobiotic metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:84735 ! algal metabolite relationship: is_conjugate_acid_of CHEBI:32486 ! L-phenylalaninate relationship: is_conjugate_base_of CHEBI:32487 ! L-phenylalaninium relationship: is_enantiomer_of CHEBI:16998 ! D-phenylalanine relationship: is_tautomer_of CHEBI:58095 ! L-phenylalanine zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H11NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-QMMMGPOBSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "165.18918" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "165.07898" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@@H](Cc1ccccc1)C(O)=O" xsd:string [Term] id: CHEBI:173085 name: ferroptosis inducer namespace: chebi_ontology def: "Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." [] subset: 3_STAR synonym: "ferroptosis inducers" RELATED [ChEBI] xref: PMID:31899616 {source="Europe PMC"} xref: PMID:32015325 {source="SUBMITTER"} xref: PMID:33167414 {source="Europe PMC"} xref: PMID:34012798 {source="Europe PMC"} xref: Wikipedia:Ferroptosis is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:17359 name: sulfite namespace: chebi_ontology alt_id: CHEBI:15139 alt_id: CHEBI:45548 def: "A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3)." [] subset: 3_STAR synonym: "[SO3](2-)" RELATED [IUPAC] synonym: "SO3" RELATED [ChEBI] synonym: "SO3(2-)" RELATED [IUPAC] synonym: "sulfite" EXACT IUPAC_NAME [IUPAC] synonym: "sulfite" EXACT [UniProt] synonym: "SULFITE ION" RELATED [PDBeChem] synonym: "sulphite" RELATED [ChEBI] synonym: "trioxidosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "trioxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "trioxosulfate(IV)" EXACT IUPAC_NAME [IUPAC] xref: CAS:14265-45-3 {source="ChemIDplus"} xref: Gmelin:1449 {source="Gmelin"} xref: PDBeChem:SO3 is_a: CHEBI:33482 ! sulfur oxoanion is_a: CHEBI:48154 ! sulfur oxide is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:17137 ! hydrogensulfite property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "80.06420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "79.95791" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S([O-])=O" xsd:string [Term] id: CHEBI:17418 name: valeric acid namespace: chebi_ontology alt_id: CHEBI:113448 alt_id: CHEBI:27263 alt_id: CHEBI:27264 alt_id: CHEBI:43606 alt_id: CHEBI:44803 alt_id: CHEBI:7980 def: "A straight-chain saturated fatty acid containing five carbon atoms." [] subset: 3_STAR synonym: "1-butanecarboxylic acid" RELATED [NIST_Chemistry_WebBook] synonym: "1-butanecarboxylic acid" RELATED [ChemIDplus] synonym: "CH3-[CH2]3-COOH" RELATED [IUPAC] synonym: "n-BuCOOH" RELATED [ChEBI] synonym: "n-Pentanoate" RELATED [KEGG_COMPOUND] synonym: "n-pentanoic acid" RELATED [ChemIDplus] synonym: "n-Valeric acid" RELATED [KEGG_COMPOUND] synonym: "n-valeric acid" RELATED [ChemIDplus] synonym: "Pentanoate" RELATED [KEGG_COMPOUND] synonym: "PENTANOIC ACID" RELATED [PDBeChem] synonym: "Pentanoic acid" RELATED [KEGG_COMPOUND] synonym: "pentanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "pentoic acid" RELATED [ChEBI] synonym: "propylacetic acid" RELATED [ChemIDplus] synonym: "Valerate" RELATED [KEGG_COMPOUND] synonym: "Valerianic acid" RELATED [KEGG_COMPOUND] synonym: "Valeriansaeure" RELATED [ChEBI] synonym: "Valeric acid" EXACT [KEGG_COMPOUND] synonym: "valeric acid, normal" RELATED [ChemIDplus] xref: Beilstein:969454 {source="Beilstein"} xref: CAS:109-52-4 {source="ChemIDplus"} xref: CAS:109-52-4 {source="NIST Chemistry WebBook"} xref: CAS:109-52-4 {source="KEGG COMPOUND"} xref: DrugBank:DB02406 xref: Gmelin:26714 {source="Gmelin"} xref: HMDB:HMDB0000892 xref: KEGG:C00803 xref: KNApSAcK:C00001208 xref: LIPID_MAPS_instance:LMFA01010005 {source="LIPID MAPS"} xref: PDBeChem:LEA xref: PMID:20507156 {source="Europe PMC"} xref: PPDB:3130 xref: Reaxys:969454 {source="Reaxys"} xref: Wikipedia:Valeric_acid is_a: CHEBI:26666 ! short-chain fatty acid is_a: CHEBI:39418 ! straight-chain saturated fatty acid relationship: has_role CHEBI:76924 ! plant metabolite relationship: is_conjugate_acid_of CHEBI:31011 ! valerate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H10O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NQPDZGIKBAWPEJ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "102.13170" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "102.06808" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCCCC(O)=O" xsd:string [Term] id: CHEBI:17478 name: aldehyde namespace: chebi_ontology alt_id: CHEBI:13432 alt_id: CHEBI:13753 alt_id: CHEBI:13805 alt_id: CHEBI:13806 alt_id: CHEBI:22291 alt_id: CHEBI:2554 alt_id: CHEBI:8750 def: "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." [] subset: 3_STAR synonym: "aldehido" RELATED [ChEBI] synonym: "aldehidos" RELATED [ChEBI] synonym: "Aldehyd" RELATED [ChEBI] synonym: "Aldehyde" EXACT [KEGG_COMPOUND] synonym: "aldehyde" EXACT [ChEBI] synonym: "aldehyde" EXACT IUPAC_NAME [IUPAC] synonym: "aldehydes" EXACT IUPAC_NAME [IUPAC] synonym: "aldehydes" RELATED [ChEBI] synonym: "aldehydum" RELATED [ChEBI] synonym: "an aldehyde" RELATED [UniProt] synonym: "RC(=O)H" RELATED [IUPAC] synonym: "RCHO" RELATED [KEGG_COMPOUND] xref: KEGG:C00071 is_a: CHEBI:36586 ! carbonyl compound relationship: has_part CHEBI:42485 ! formyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHOR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "29.01800" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "29.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C([*])=O" xsd:string [Term] id: CHEBI:17544 name: hydrogencarbonate namespace: chebi_ontology alt_id: CHEBI:13363 alt_id: CHEBI:22863 alt_id: CHEBI:40961 alt_id: CHEBI:5589 def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." [] subset: 3_STAR synonym: "[CO2(OH)](-)" RELATED [IUPAC] synonym: "Acid carbonate" RELATED [KEGG_COMPOUND] synonym: "Bicarbonate" RELATED [KEGG_COMPOUND] synonym: "BICARBONATE ION" RELATED [PDBeChem] synonym: "HCO3(-)" RELATED [IUPAC] synonym: "HCO3-" RELATED [KEGG_COMPOUND] synonym: "hydrogen carbonate" RELATED [PDBeChem] synonym: "hydrogen(trioxidocarbonate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND] synonym: "hydrogencarbonate" EXACT [UniProt] synonym: "hydrogencarbonate" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogencarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(IV)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidodioxidocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3903504 {source="Beilstein"} xref: CAS:71-52-3 {source="ChemIDplus"} xref: Gmelin:49249 {source="Gmelin"} xref: HMDB:HMDB0000595 xref: KEGG:C00288 xref: MetaCyc:HCO3 xref: PDBeChem:BCT xref: PMID:17215880 {source="Europe PMC"} xref: PMID:17505962 {source="Europe PMC"} xref: PMID:18439416 {source="Europe PMC"} xref: PMID:28732801 {source="Europe PMC"} xref: PMID:29150416 {source="Europe PMC"} xref: PMID:29460248 {source="Europe PMC"} xref: PMID:29466234 {source="Europe PMC"} xref: PMID:4208463 {source="Europe PMC"} xref: Wikipedia:Bicarbonate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35604 ! carbon oxoanion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:41609 ! carbonate relationship: is_conjugate_base_of CHEBI:28976 ! carbonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "61.01684" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.99312" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([O-])=O" xsd:string [Term] id: CHEBI:17568 name: uracil namespace: chebi_ontology alt_id: CHEBI:15288 alt_id: CHEBI:27210 alt_id: CHEBI:46375 alt_id: CHEBI:9882 def: "A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription." [] subset: 3_STAR synonym: "2,4(1H,3H)-pyrimidinedione" RELATED [NIST_Chemistry_WebBook] synonym: "2,4-Dioxopyrimidine" RELATED [HMDB] synonym: "2,4-Pyrimidinedione" RELATED [HMDB] synonym: "pyrimidine-2,4(1H,3H)-dione" EXACT IUPAC_NAME [IUPAC] synonym: "U" RELATED [ChEBI] synonym: "Ura" RELATED [CBN] synonym: "URACIL" EXACT [PDBeChem] synonym: "Uracil" EXACT [KEGG_COMPOUND] synonym: "uracil" EXACT [UniProt] synonym: "Urazil" RELATED [ChEBI] xref: Beilstein:606623 {source="Beilstein"} xref: CAS:66-22-8 {source="NIST Chemistry WebBook"} xref: CAS:66-22-8 {source="KEGG COMPOUND"} xref: CAS:66-22-8 {source="ChemIDplus"} xref: DrugBank:DB03419 xref: Gmelin:2896 {source="Gmelin"} xref: HMDB:HMDB0000300 xref: KEGG:C00106 xref: KEGG:D00027 xref: KNApSAcK:C00001513 xref: MetaCyc:URACIL xref: PDBeChem:URA xref: PMID:11279060 {source="Europe PMC"} xref: PMID:12855717 {source="Europe PMC"} xref: PMID:15274295 {source="Europe PMC"} xref: PMID:16834123 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:18533995 {source="Europe PMC"} xref: PMID:18815805 {source="Europe PMC"} xref: PMID:19175333 {source="Europe PMC"} xref: PMID:22020693 {source="Europe PMC"} xref: PMID:22074393 {source="Europe PMC"} xref: PMID:22120518 {source="Europe PMC"} xref: PMID:22171528 {source="Europe PMC"} xref: PMID:22237209 {source="Europe PMC"} xref: PMID:22299724 {source="Europe PMC"} xref: PMID:22356544 {source="Europe PMC"} xref: PMID:22447672 {source="Europe PMC"} xref: PMID:22483865 {source="Europe PMC"} xref: PMID:22567906 {source="Europe PMC"} xref: PMID:22685418 {source="Europe PMC"} xref: PMID:3654008 {source="Europe PMC"} xref: Reaxys:606623 {source="Reaxys"} xref: Wikipedia:Uracil is_a: BFO:0000004 ! independent continuant is_a: CHEBI:26432 ! pyrimidine nucleobase is_a: CHEBI:38337 ! pyrimidone relationship: has_role CHEBI:50266 ! prodrug relationship: has_role CHEBI:50904 ! allergen relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:83056 ! Daphnia magna metabolite relationship: is_tautomer_of CHEBI:43254 ! (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H4N2O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ISAKRJDGNUQOIC-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "112.08684" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "112.02728" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=c1cc[nH]c(=O)[nH]1" xsd:string [Term] id: CHEBI:17578 name: toluene namespace: chebi_ontology alt_id: CHEBI:15248 alt_id: CHEBI:27022 alt_id: CHEBI:44023 alt_id: CHEBI:9624 def: "The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent." [] subset: 3_STAR synonym: "methylbenzene" RELATED [PDBeChem] synonym: "phenylmethane" RELATED [ChemIDplus] synonym: "Toluen" RELATED [NIST_Chemistry_WebBook] synonym: "TOLUENE" EXACT [PDBeChem] synonym: "Toluene" EXACT [KEGG_COMPOUND] synonym: "toluene" EXACT [ChEBI] synonym: "toluene" EXACT [UniProt] synonym: "toluene" EXACT IUPAC_NAME [IUPAC] synonym: "Toluol" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:635760 {source="Beilstein"} xref: CAS:108-88-3 {source="KEGG COMPOUND"} xref: CAS:108-88-3 {source="NIST Chemistry WebBook"} xref: CAS:108-88-3 {source="ChemIDplus"} xref: DrugBank:DB01900 xref: Gmelin:2456 {source="Gmelin"} xref: KEGG:C01455 xref: PDBeChem:MBN xref: PMID:11182169 {source="Europe PMC"} xref: PMID:11314682 {source="Europe PMC"} xref: PMID:11846266 {source="Europe PMC"} xref: PMID:11991009 {source="Europe PMC"} xref: PMID:12062755 {source="Europe PMC"} xref: PMID:12213539 {source="Europe PMC"} xref: PMID:12237258 {source="Europe PMC"} xref: PMID:12784113 {source="Europe PMC"} xref: PMID:12876426 {source="Europe PMC"} xref: PMID:14512097 {source="Europe PMC"} xref: PMID:14559343 {source="Europe PMC"} xref: PMID:14605898 {source="Europe PMC"} xref: PMID:15015825 {source="Europe PMC"} xref: PMID:15019953 {source="Europe PMC"} xref: PMID:15119846 {source="Europe PMC"} xref: PMID:15193425 {source="Europe PMC"} xref: PMID:15542760 {source="Europe PMC"} xref: PMID:15567510 {source="Europe PMC"} xref: PMID:15695158 {source="Europe PMC"} xref: PMID:15796064 {source="Europe PMC"} xref: PMID:16316648 {source="Europe PMC"} xref: PMID:16348226 {source="Europe PMC"} xref: PMID:16601996 {source="Europe PMC"} xref: PMID:17145141 {source="Europe PMC"} xref: PMID:17175136 {source="Europe PMC"} xref: PMID:17497535 {source="Europe PMC"} xref: PMID:17725881 {source="Europe PMC"} xref: PMID:18397809 {source="Europe PMC"} xref: PMID:18832024 {source="Europe PMC"} xref: PMID:19261054 {source="Europe PMC"} xref: PMID:19384711 {source="Europe PMC"} xref: PMID:19429395 {source="Europe PMC"} xref: PMID:19635754 {source="Europe PMC"} xref: PMID:19765629 {source="Europe PMC"} xref: PMID:19825861 {source="Europe PMC"} xref: PMID:19928203 {source="Europe PMC"} xref: PMID:19969016 {source="Europe PMC"} xref: PMID:20347282 {source="Europe PMC"} xref: PMID:20837561 {source="Europe PMC"} xref: PMID:21430649 {source="Europe PMC"} xref: PMID:21655021 {source="Europe PMC"} xref: PMID:21731073 {source="Europe PMC"} xref: PMID:21802510 {source="Europe PMC"} xref: PMID:21840036 {source="Europe PMC"} xref: Reaxys:635760 {source="Reaxys"} xref: UM-BBD_compID:c0114 {source="UM-BBD"} xref: Wikipedia:Toluene is_a: BFO:0000004 ! independent continuant is_a: CHEBI:134179 ! volatile organic compound is_a: CHEBI:27024 ! toluenes is_a: CHEBI:38975 ! methylbenzene relationship: has_role CHEBI:48355 ! non-polar solvent relationship: has_role CHEBI:48873 ! cholinergic antagonist relationship: has_role CHEBI:50910 ! neurotoxin relationship: has_role CHEBI:62803 ! fuel additive property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H8" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YXFVVABEGXRONW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "92.13842" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "92.06260" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cc1ccccc1" xsd:string [Term] id: CHEBI:17590 name: octane namespace: chebi_ontology alt_id: CHEBI:14680 alt_id: CHEBI:25465 alt_id: CHEBI:25645 alt_id: CHEBI:44621 alt_id: CHEBI:7723 def: "A straight chain alkane composed of 8 carbon atoms." [] subset: 3_STAR synonym: "CH3-[CH2]6-CH3" RELATED [IUPAC] synonym: "N-OCTANE" RELATED [PDBeChem] synonym: "n-Octane" RELATED [KEGG_COMPOUND] synonym: "n-Oktan" RELATED [ChEBI] synonym: "Octane" EXACT [KEGG_COMPOUND] synonym: "octane" EXACT IUPAC_NAME [IUPAC] synonym: "octane" EXACT [UniProt] synonym: "Oktan" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1696875 {source="Beilstein"} xref: CAS:111-65-9 {source="KEGG COMPOUND"} xref: CAS:111-65-9 {source="NIST Chemistry WebBook"} xref: CAS:111-65-9 {source="ChemIDplus"} xref: DrugBank:DB02440 xref: Gmelin:82412 {source="Gmelin"} xref: HMDB:HMDB0001485 xref: KEGG:C01387 xref: LIPID_MAPS_instance:LMFA11000002 {source="LIPID MAPS"} xref: MetaCyc:CPD-148 xref: PDBeChem:OCT xref: PMID:11255151 {source="Europe PMC"} xref: PMID:24354334 {source="Europe PMC"} xref: Reaxys:1696875 {source="Reaxys"} xref: UM-BBD_compID:c0044 {source="UM-BBD"} xref: Wikipedia:Octane is_a: BFO:0000004 ! independent continuant is_a: CHEBI:18310 ! alkane relationship: has_role CHEBI:35703 ! xenobiotic property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H18" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H18/c1-3-5-7-8-6-4-2/h3-8H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "TVMXDCGIABBOFY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "114.22852" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "114.14085" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCCCCCCC" xsd:string [Term] id: CHEBI:17594 name: hydroquinone namespace: chebi_ontology alt_id: CHEBI:14416 alt_id: CHEBI:24645 alt_id: CHEBI:5793 def: "A benzenediol comprising benzene core carrying two hydroxy substituents para to each other." [] subset: 3_STAR synonym: "1,4-Benzenediol" RELATED [KEGG_COMPOUND] synonym: "1,4-Dihydroxybenzene" RELATED [KEGG_COMPOUND] synonym: "4-Hydroxyphenol" RELATED [KEGG_COMPOUND] synonym: "Benzene-1,4-diol" RELATED [KEGG_COMPOUND] synonym: "benzene-1,4-diol" EXACT IUPAC_NAME [IUPAC] synonym: "Eldoquin" RELATED [ChemIDplus] synonym: "Hydroquinone" EXACT [KEGG_COMPOUND] synonym: "hydroquinone" EXACT [UniProt] synonym: "p-Benzenediol" RELATED [KEGG_COMPOUND] synonym: "p-Hydroquinone" RELATED [KEGG_COMPOUND] synonym: "p-hydroxyphenol" RELATED [NIST_Chemistry_WebBook] synonym: "Quinol" RELATED [KEGG_COMPOUND] xref: Beilstein:605970 {source="Beilstein"} xref: CAS:123-31-9 {source="ChemIDplus"} xref: CAS:123-31-9 {source="NIST Chemistry WebBook"} xref: CAS:123-31-9 {source="KEGG COMPOUND"} xref: Drug_Central:3282 {source="DrugCentral"} xref: Gmelin:2742 {source="Gmelin"} xref: HMDB:HMDB0002434 xref: KEGG:C00530 xref: KEGG:C15603 xref: KEGG:D00073 xref: KNApSAcK:C00002656 xref: MetaCyc:HYDROQUINONE xref: PMID:11170505 {source="Europe PMC"} xref: PMID:12213471 {source="Europe PMC"} xref: PMID:1395635 {source="Europe PMC"} xref: PMID:15618234 {source="Europe PMC"} xref: PMID:15894107 {source="Europe PMC"} xref: PMID:1899343 {source="Europe PMC"} xref: PMID:19148301 {source="Europe PMC"} xref: PMID:24407054 {source="Europe PMC"} xref: PMID:24858384 {source="Europe PMC"} xref: PMID:25586344 {source="Europe PMC"} xref: PPDB:1503 xref: Reaxys:605970 {source="Reaxys"} xref: UM-BBD_compID:c0091 {source="UM-BBD"} xref: Wikipedia:Hydroquinone is_a: BFO:0000004 ! independent continuant is_a: CHEBI:17701 ! benzenediol is_a: CHEBI:24646 ! hydroquinones relationship: has_role CHEBI:22586 ! antioxidant relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76967 ! human xenobiotic metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:85046 ! skin lightening agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H6O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QIGBRXMKCJKVMJ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "110.11064" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "110.03678" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Oc1ccc(O)cc1" xsd:string [Term] id: CHEBI:176497 name: geroprotector namespace: chebi_ontology def: "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." [] subset: 3_STAR synonym: "anti-aging agent" RELATED [ChEBI] synonym: "anti-aging agents" RELATED [ChEBI] synonym: "anti-aging drug" RELATED [ChEBI] synonym: "anti-aging drugs" RELATED [ChEBI] synonym: "geroprotective agent" RELATED [ChEBI] synonym: "geroprotective agents" RELATED [ChEBI] synonym: "geroprotectors" RELATED [ChEBI] xref: PMID:23372317 {source="Europe PMC"} xref: PMID:28580190 {source="Europe PMC"} xref: PMID:30885572 {source="Europe PMC"} xref: PMID:33144142 {source="Europe PMC"} xref: PMID:33973253 {source="Europe PMC"} xref: Wikipedia:Geroprotector is_a: CHEBI:50267 ! protective agent [Term] id: CHEBI:176842 name: vitamin B9 namespace: chebi_ontology def: "Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin." [] subset: 3_STAR synonym: "folate vitamer" RELATED [ChEBI] synonym: "folate vitamers" RELATED [ChEBI] synonym: "vitamin B-9" RELATED [ChEBI] synonym: "vitamin B9" EXACT [ChEBI] synonym: "vitamin B9 vitamer" RELATED [ChEBI] synonym: "vitamin B9 vitamers" RELATED [ChEBI] synonym: "vitamins B9" RELATED [ChEBI] is_a: CHEBI:75769 ! B vitamin [Term] id: CHEBI:17701 name: benzenediol namespace: chebi_ontology alt_id: CHEBI:13878 alt_id: CHEBI:3027 subset: 3_STAR synonym: "Benzenediol" EXACT [KEGG_COMPOUND] synonym: "benzenediol" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxybenzene" RELATED [ChEBI] xref: CAS:12385-08-9 {source="ChemIDplus"} xref: CAS:12385-08-9 {source="KEGG COMPOUND"} xref: KEGG:C01785 is_a: CHEBI:33570 ! benzenediols property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H6O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "110.111" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "110.03678" xsd:string [Term] id: CHEBI:17748 name: thymidine namespace: chebi_ontology alt_id: CHEBI:15244 alt_id: CHEBI:19273 alt_id: CHEBI:45782 alt_id: CHEBI:45834 alt_id: CHEBI:45917 alt_id: CHEBI:9579 def: "A pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase." [] subset: 3_STAR synonym: "1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione" RELATED [ChEBI] synonym: "2'-deoxy-5-methyluridine" RELATED [ChemIDplus] synonym: "2'-deoxythymidine" RELATED [ChemIDplus] synonym: "2'-thymidine" RELATED [ChEBI] synonym: "5-methyl-2'-deoxyuridine" RELATED [ChemIDplus] synonym: "Deoxythymidine" RELATED [KEGG_COMPOUND] synonym: "dThd" RELATED [CBN] synonym: "T" RELATED [ChEBI] synonym: "THYMIDINE" EXACT [PDBeChem] synonym: "Thymidine" EXACT [KEGG_COMPOUND] synonym: "thymidine" EXACT IUPAC_NAME [IUPAC] synonym: "thymidine" EXACT [UniProt] synonym: "thymine 2'-deoxyriboside" RELATED [ChEBI] xref: Beilstein:89285 {source="Beilstein"} xref: CAS:50-89-5 {source="KEGG COMPOUND"} xref: CAS:50-89-5 {source="ChemIDplus"} xref: DrugBank:DB04485 xref: Gmelin:282610 {source="Gmelin"} xref: HMDB:HMDB0000273 xref: KEGG:C00214 xref: KNApSAcK:C00019698 xref: MetaCyc:THYMIDINE xref: PDBeChem:THM xref: PMID:22770225 {source="Europe PMC"} xref: PMID:2559771 {source="Europe PMC"} xref: Reaxys:89285 {source="Reaxys"} xref: Wikipedia:Thymidine is_a: BFO:0000004 ! independent continuant is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside relationship: has_functional_parent CHEBI:17821 ! thymine relationship: has_role CHEBI:25212 ! metabolite relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_enantiomer_of CHEBI:63624 ! telbivudine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H14N2O5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IQFYYKKMVGJFEH-XLPZGREQSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "242.22860" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "242.09027" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O" xsd:string [Term] id: CHEBI:17792 name: organohalogen compound namespace: chebi_ontology alt_id: CHEBI:13444 alt_id: CHEBI:36684 alt_id: CHEBI:8767 def: "A compound containing at least one carbon-halogen bond (where X is a halogen atom)." [] subset: 3_STAR synonym: "organic halide" RELATED [KEGG_COMPOUND] synonym: "organic halides" RELATED [ChEBI] synonym: "organohalogen compounds" RELATED [ChEBI] synonym: "RX" RELATED [UniProt] synonym: "RX" RELATED [KEGG_COMPOUND] xref: KEGG:C01322 xref: MetaCyc:Organohalogen-Compounds is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:37578 ! halide property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "RX" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "**" xsd:string [Term] id: CHEBI:17821 name: thymine namespace: chebi_ontology alt_id: CHEBI:15247 alt_id: CHEBI:27004 alt_id: CHEBI:46017 alt_id: CHEBI:9580 def: "A pyrimidine nucleobase that is uracil in which the hydrogen at position 5 is replaced by a methyl group." [] subset: 3_STAR synonym: "2,4-dihydroxy-5-methylpyrimidine" RELATED [NIST_Chemistry_WebBook] synonym: "5-methyl-2,4(1H,3H)-pyrimidinedione" RELATED [NIST_Chemistry_WebBook] synonym: "5-methylpyrimidine-2,4(1H,3H)-dione" RELATED [IUPAC] synonym: "5-Methyluracil" RELATED [KEGG_COMPOUND] synonym: "5-methyluracil" RELATED [NIST_Chemistry_WebBook] synonym: "T" RELATED [ChEBI] synonym: "Thy" RELATED [CBN] synonym: "Thymin" RELATED [ChemIDplus] synonym: "THYMINE" EXACT [PDBeChem] synonym: "Thymine" EXACT [KEGG_COMPOUND] synonym: "thymine" EXACT [UniProt] synonym: "thymine" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:607626 {source="Beilstein"} xref: CAS:65-71-4 {source="NIST Chemistry WebBook"} xref: CAS:65-71-4 {source="ChemIDplus"} xref: CAS:65-71-4 {source="KEGG COMPOUND"} xref: DrugBank:DB03462 xref: Gmelin:278790 {source="Gmelin"} xref: KEGG:C00178 xref: KNApSAcK:C00001511 xref: PDBeChem:TDR xref: PMID:23237383 {source="Europe PMC"} xref: Wikipedia:Thymine is_a: BFO:0000004 ! independent continuant is_a: CHEBI:26432 ! pyrimidine nucleobase is_a: CHEBI:38337 ! pyrimidone relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H6N2O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RWQNBRDOKXIBIV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "126.11342" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "126.04293" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cc1c[nH]c(=O)[nH]c1=O" xsd:string [Term] id: CHEBI:17883 name: hydrogen chloride namespace: chebi_ontology alt_id: CHEBI:13364 alt_id: CHEBI:24635 alt_id: CHEBI:5590 def: "A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms." [] subset: 3_STAR synonym: "[HCl]" RELATED [IUPAC] synonym: "chlorane" EXACT IUPAC_NAME [IUPAC] synonym: "chloridohydrogen" EXACT IUPAC_NAME [IUPAC] synonym: "chlorure d'hydrogene" RELATED [ChEBI] synonym: "Chlorwasserstoff" RELATED [ChEBI] synonym: "cloruro de hidrogeno" RELATED [ChEBI] synonym: "HCl" RELATED [KEGG_COMPOUND] synonym: "hydrochloric acid" RELATED [ChemIDplus] synonym: "Hydrochloride" RELATED [KEGG_COMPOUND] synonym: "Hydrogen chloride" EXACT [KEGG_COMPOUND] synonym: "hydrogen chloride" EXACT IUPAC_NAME [IUPAC] synonym: "Hydrogenchlorid" RELATED [ChEBI] synonym: "Wasserstoffchlorid" RELATED [ChEBI] xref: CAS:7647-01-0 {source="ChemIDplus"} xref: CAS:7647-01-0 {source="NIST Chemistry WebBook"} xref: CAS:7647-01-0 {source="KEGG COMPOUND"} xref: Drug_Central:4568 {source="DrugCentral"} xref: Gmelin:322 {source="Gmelin"} xref: HMDB:HMDB0002306 xref: KEGG:C01327 xref: KEGG:D02057 xref: MetaCyc:HCL xref: PMID:15823700 {source="Europe PMC"} xref: PMID:17492841 {source="Europe PMC"} xref: PMID:22804993 {source="Europe PMC"} xref: Reaxys:1098214 {source="Reaxys"} xref: Wikipedia:HCl xref: Wikipedia:Hydrochloric_acid is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:18140 ! hydrogen halide is_a: CHEBI:23117 ! chlorine molecular entity is_a: CHEBI:37176 ! mononuclear parent hydride relationship: has_role CHEBI:75771 ! mouse metabolite relationship: is_conjugate_acid_of CHEBI:17996 ! chloride relationship: is_conjugate_base_of CHEBI:50315 ! chloronium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "ClH" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HCl" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/ClH/h1H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "VEXZGXHMUGYJMC-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "36.46064" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "35.97668" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cl[H]" xsd:string [Term] id: CHEBI:17891 name: donor namespace: chebi_ontology alt_id: CHEBI:14202 alt_id: CHEBI:4697 def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." [] subset: 3_STAR synonym: "Donator" RELATED [ChEBI] synonym: "donneur" RELATED [ChEBI] synonym: "Donor" EXACT [KEGG_COMPOUND] xref: KEGG:C01351 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:17967 name: urethane namespace: chebi_ontology alt_id: CHEBI:15295 alt_id: CHEBI:27225 alt_id: CHEBI:9892 def: "A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages." [] subset: 3_STAR synonym: "carbamic acid ethyl ester" RELATED [ChEBI] synonym: "Ethyl carbamate" RELATED [KEGG_COMPOUND] synonym: "ethyl carbamate" EXACT IUPAC_NAME [IUPAC] synonym: "Urethane" EXACT [KEGG_COMPOUND] synonym: "urethane" EXACT [UniProt] xref: CAS:51-79-6 {source="KEGG COMPOUND"} xref: DrugBank:DB04827 xref: HMDB:HMDB0031219 xref: KEGG:C01537 xref: LINCS:LSM-37020 xref: PMID:15790490 {source="Europe PMC"} xref: PMID:24386880 {source="Europe PMC"} xref: Reaxys:635810 {source="Reaxys"} xref: Wikipedia:Ethyl_carbamate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:13941 ! carbamate is_a: CHEBI:23003 ! carbamate ester is_a: FBcv:0000538 ! carbamate is_a: FBcv:0000539 ! urethane equivalent_to: FBcv:0000539 ! urethane relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:76946 ! fungal metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H7NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H7NO2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JOYRKODLDBILNP-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "89.09322" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "89.04768" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCOC(N)=O" xsd:string [Term] id: CHEBI:17996 name: chloride namespace: chebi_ontology alt_id: CHEBI:13291 alt_id: CHEBI:13970 alt_id: CHEBI:3616 alt_id: CHEBI:3731 alt_id: CHEBI:48804 def: "A halide anion formed when chlorine picks up an electron to form an an anion." [] subset: 3_STAR synonym: "Chloride" EXACT [KEGG_COMPOUND] synonym: "chloride" EXACT [UniProt] synonym: "chloride" EXACT IUPAC_NAME [IUPAC] synonym: "CHLORIDE ION" RELATED [PDBeChem] synonym: "Chloride ion" RELATED [KEGG_COMPOUND] synonym: "Chloride(1-)" RELATED [ChemIDplus] synonym: "chloride(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "Chlorine anion" RELATED [NIST_Chemistry_WebBook] synonym: "Cl(-)" RELATED [IUPAC] synonym: "Cl-" RELATED [KEGG_COMPOUND] xref: Beilstein:3587171 {source="Beilstein"} xref: CAS:16887-00-6 {source="ChemIDplus"} xref: CAS:16887-00-6 {source="NIST Chemistry WebBook"} xref: CAS:16887-00-6 {source="KEGG COMPOUND"} xref: Gmelin:14910 {source="Gmelin"} xref: KEGG:C00115 xref: KEGG:C00698 xref: PDBeChem:CL xref: UM-BBD_compID:c0884 {source="UM-BBD"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:16042 ! halide anion is_a: CHEBI:33432 ! monoatomic chlorine relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:17883 ! hydrogen chloride property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Cl" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/ClH/h1H/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "VEXZGXHMUGYJMC-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "35.45270" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "34.96940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Cl-]" xsd:string [Term] id: CHEBI:18059 name: lipid namespace: chebi_ontology alt_id: CHEBI:14517 alt_id: CHEBI:25054 alt_id: CHEBI:6486 def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." [] subset: 3_STAR synonym: "Lipid" EXACT [KEGG_COMPOUND] synonym: "lipids" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C01356 is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:18140 name: hydrogen halide namespace: chebi_ontology alt_id: CHEBI:13368 alt_id: CHEBI:37140 alt_id: CHEBI:5599 subset: 3_STAR synonym: "HX" RELATED [UniProt] synonym: "hydrogen halide" EXACT [IUPAC] synonym: "hydrogen halides" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen halides" RELATED [ChEBI] is_a: CHEBI:33405 ! hydracid relationship: has_role CHEBI:138103 ! inorganic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HX" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1.008" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.00783" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[F,Cl,Br,I]" xsd:string [Term] id: CHEBI:18237 name: glutamic acid namespace: chebi_ontology alt_id: CHEBI:24314 alt_id: CHEBI:5431 def: "An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2." [] subset: 3_STAR synonym: "2-Aminoglutaric acid" RELATED [KEGG_COMPOUND] synonym: "2-aminopentanedioic acid" EXACT IUPAC_NAME [IUPAC] synonym: "DL-Glutamic acid" RELATED [KEGG_DRUG] synonym: "DL-Glutaminic acid" RELATED [KEGG_COMPOUND] synonym: "E" RELATED [ChEBI] synonym: "Glu" RELATED [ChEBI] synonym: "Glutamate" RELATED [KEGG_COMPOUND] synonym: "Glutamic acid" EXACT [KEGG_COMPOUND] synonym: "glutamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Glutaminic acid" RELATED [KEGG_COMPOUND] synonym: "Glutaminsaeure" RELATED [ChEBI] xref: Beilstein:1723799 {source="Beilstein"} xref: CAS:617-65-2 {source="ChemIDplus"} xref: CAS:617-65-2 {source="NIST Chemistry WebBook"} xref: CAS:617-65-2 {source="KEGG COMPOUND"} xref: Gmelin:101971 {source="Gmelin"} xref: KEGG:C00302 xref: KEGG:D04341 xref: KNApSAcK:C00001358 xref: KNApSAcK:C00019577 xref: PMID:15739367 {source="Europe PMC"} xref: PMID:17190852 {source="Europe PMC"} xref: PMID:24616376 {source="Europe PMC"} xref: PMID:24984001 {source="Europe PMC"} xref: Reaxys:1723799 {source="Reaxys"} xref: Wikipedia:Glutamic_acid is_a: CHEBI:26167 ! polar amino acid is_a: CHEBI:33704 ! alpha-amino acid relationship: has_part CHEBI:50329 ! 2-carboxyethyl group relationship: has_role CHEBI:78675 ! fundamental metabolite relationship: is_conjugate_acid_of CHEBI:14321 ! glutamate(1-) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "147.12930" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "147.05316" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(CCC(O)=O)C(O)=O" xsd:string [Term] id: CHEBI:18254 name: ribonucleoside namespace: chebi_ontology alt_id: CHEBI:13014 alt_id: CHEBI:13015 alt_id: CHEBI:13685 alt_id: CHEBI:21085 alt_id: CHEBI:26560 alt_id: CHEBI:4240 alt_id: CHEBI:8844 def: "Any nucleoside where the sugar component is D-ribose." [] subset: 3_STAR synonym: "a ribonucleoside" RELATED [UniProt] synonym: "Ribonucleoside" EXACT [KEGG_COMPOUND] synonym: "ribonucleosides" RELATED [ChEBI] xref: KEGG:C00911 is_a: CHEBI:33838 ! nucleoside is_a: CHEBI:47019 ! dihydroxytetrahydrofuran property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9O4R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "133.123" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "133.05008" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O" xsd:string [Term] id: CHEBI:18274 name: 2'-deoxyribonucleoside namespace: chebi_ontology alt_id: CHEBI:1083 alt_id: CHEBI:11394 alt_id: CHEBI:11567 alt_id: CHEBI:11568 alt_id: CHEBI:19259 alt_id: CHEBI:19560 alt_id: CHEBI:4421 subset: 3_STAR synonym: "2'-Deoxynucleoside" RELATED [KEGG_COMPOUND] synonym: "2'-deoxyribonucleosides" RELATED [ChEBI] synonym: "2-Deoxy-D-ribosyl-base" RELATED [KEGG_COMPOUND] synonym: "a 2'-deoxyribonucleoside" RELATED [UniProt] synonym: "Deoxynucleoside" RELATED [KEGG_COMPOUND] xref: KEGG:C02269 xref: KEGG:C03216 is_a: CHEBI:23636 ! deoxyribonucleoside is_a: CHEBI:47018 ! monohydroxytetrahydrofuran property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9O3R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "117.123" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "117.05517" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC[C@H]1O[C@@H]([*])C[C@@H]1O" xsd:string [Term] id: CHEBI:18282 name: nucleobase namespace: chebi_ontology alt_id: CHEBI:13873 alt_id: CHEBI:25598 alt_id: CHEBI:2995 def: "That part of DNA or RNA that may be involved in pairing." [] subset: 3_STAR synonym: "Base" RELATED [KEGG_COMPOUND] synonym: "nucleobases" RELATED [ChEBI] xref: KEGG:C00701 xref: Wikipedia:Nucleobase is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:18310 name: alkane namespace: chebi_ontology alt_id: CHEBI:13435 alt_id: CHEBI:22317 alt_id: CHEBI:2576 def: "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." [] subset: 3_STAR synonym: "alcane" RELATED [IUPAC] synonym: "alcanes" RELATED [IUPAC] synonym: "alcano" RELATED [IUPAC] synonym: "alcanos" RELATED [IUPAC] synonym: "Alkan" RELATED [ChEBI] synonym: "Alkane" EXACT [KEGG_COMPOUND] synonym: "alkane" EXACT IUPAC_NAME [IUPAC] synonym: "alkanes" EXACT IUPAC_NAME [IUPAC] synonym: "an alkane" RELATED [UniProt] synonym: "RH" RELATED [KEGG_COMPOUND] xref: KEGG:C01371 is_a: CHEBI:24632 ! hydrocarbon is_a: CHEBI:33653 ! aliphatic compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.035" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.02348" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[*]" xsd:string [Term] id: CHEBI:18367 name: phosphate(3-) namespace: chebi_ontology alt_id: CHEBI:14791 alt_id: CHEBI:45024 alt_id: CHEBI:7793 def: "A phosphate ion that is the conjugate base of hydrogenphosphate." [] subset: 3_STAR synonym: "[PO4](3-)" RELATED [IUPAC] synonym: "Orthophosphate" RELATED [KEGG_COMPOUND] synonym: "Phosphate" RELATED [KEGG_COMPOUND] synonym: "phosphate" EXACT IUPAC_NAME [IUPAC] synonym: "PHOSPHATE ION" RELATED [PDBeChem] synonym: "PO4(3-)" RELATED [IUPAC] synonym: "tetraoxidophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3903772 {source="Beilstein"} xref: CAS:14265-44-2 {source="KEGG COMPOUND"} xref: CAS:14265-44-2 {source="ChemIDplus"} xref: Gmelin:1997 {source="Gmelin"} xref: KEGG:C00009 xref: PDBeChem:PO4 {source="ChEBI"} xref: Reaxys:3903772 {source="Reaxys"} is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79387 ! trivalent inorganic anion relationship: is_conjugate_base_of CHEBI:43474 ! hydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-K" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "94.97136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.95507" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]P([O-])([O-])=O" xsd:string [Term] id: CHEBI:19024 name: 4-amino-3-hydroxynaphthalene-1-sulfonic acid namespace: chebi_ontology subset: 3_STAR synonym: "1-amino-2-naphthol-4-sulfonic acid" RELATED [ChemIDplus] synonym: "1-amino-4-sulfo-2-naphthol" RELATED [ChemIDplus] synonym: "4-amino-3-hydroxynaphthalene-1-sulfonic acid" EXACT IUPAC_NAME [IUPAC] synonym: "4-amino-3-hydroxynaphthalene-1-sulphonic acid" RELATED [ChemIDplus] xref: Beilstein:2697469 {source="Beilstein"} xref: CAS:116-63-2 {source="NIST Chemistry WebBook"} xref: CAS:116-63-2 {source="ChemIDplus"} xref: Gmelin:241697 {source="Gmelin"} is_a: CHEBI:36336 ! naphthalenesulfonic acid is_a: CHEBI:38034 ! aminonaphthalene is_a: FBcv:0000568 ! 1-amino-2-naphthol-4-sulfonic acid equivalent_to: FBcv:0000568 ! 1-amino-2-naphthol-4-sulfonic acid relationship: has_functional_parent CHEBI:10432 ! 2-naphthol relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H9NO4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H9NO4S/c11-10-7-4-2-1-3-6(7)9(5-8(10)12)16(13,14)15/h1-5,12H,11H2,(H,13,14,15)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RXCMFQDTWCCLBL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "239.24880" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "239.02523" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Nc1c(O)cc(c2ccccc12)S(O)(=O)=O" xsd:string [Term] id: CHEBI:19032 name: 1-bromo-2-chloroethane namespace: chebi_ontology def: "A haloalkane that is bromoethane substituted by chlorine at position 2." [] subset: 3_STAR synonym: "1,2-bromochloroethane" RELATED [NIST_Chemistry_WebBook] synonym: "1,2-chlorobromoethane" RELATED [ChemIDplus] synonym: "1-bromo-2-chloroethane" EXACT IUPAC_NAME [IUPAC] synonym: "2-bromo-1-chloroethane" RELATED [ChemIDplus] synonym: "2-bromoethyl chloride" RELATED [NIST_Chemistry_WebBook] synonym: "2-chloroethyl bromide" RELATED [NIST_Chemistry_WebBook] synonym: "beta-chloroethyl bromide" RELATED [NIST_Chemistry_WebBook] synonym: "ethylene chlorobromide" RELATED [ChemIDplus] xref: Beilstein:605265 {source="Beilstein"} xref: CAS:107-04-0 {source="NIST Chemistry WebBook"} xref: CAS:107-04-0 {source="ChemIDplus"} xref: Gmelin:984479 {source="Gmelin"} xref: PMID:6357525 {source="Europe PMC"} xref: PMID:8200089 {source="Europe PMC"} xref: Reaxys:605265 {source="Reaxys"} is_a: CHEBI:24469 ! haloalkane is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:37141 ! organobromine compound is_a: FBcv:0000541 ! intercalating agent is_a: FBcv:0000547 ! 1-bromo-2-chloroethane equivalent_to: FBcv:0000547 ! 1-bromo-2-chloroethane relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4BrCl" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4BrCl/c3-1-2-4/h1-2H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IBYHHJPAARCAIE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "143.40986" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "141.91849" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "ClCCBr" xsd:string [Term] id: CHEBI:19255 name: pyrimidine 2'-deoxyribonucleoside namespace: chebi_ontology subset: 3_STAR synonym: "pyrimidine 2'-deoxyribonucleosides" RELATED [ChEBI] is_a: CHEBI:18274 ! 2'-deoxyribonucleoside is_a: CHEBI:68472 ! pyrimidine deoxyribonucleoside [Term] id: CHEBI:19363 name: 2,5-bis(aziridin-1-yl)-1,4-benzoquinone namespace: chebi_ontology def: "A member of the class of 1,4-benzoquinones that is p-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups." [] subset: 3_STAR synonym: "2,5,-bis(ethyleneimine)-1,4-benzoquinone" RELATED [ChEBI] synonym: "2,5,-bisethylene-imine-1,4-benzoquinone" RELATED [ChEBI] synonym: "2,5-bis(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione" RELATED [ChemIDplus] synonym: "2,5-bis(1-aziridinyl)-p-benzoquinone" RELATED [ChemIDplus] synonym: "2,5-bis(1-aziridynyl)benzoquinone" RELATED [ChemIDplus] synonym: "2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione" EXACT IUPAC_NAME [IUPAC] synonym: "2,5-bis(aziridino)-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "2,5-bis(aziridino)benzoquinone" RELATED [ChemIDplus] synonym: "2,5-bis(ethyleneimino)-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "2,5-bis-ethyleniminobenzoquinone" RELATED [ChemIDplus] synonym: "2,5-Bisaethyleniminobenzochinon-1,4" RELATED [ChEBI] synonym: "2,5-bisethyleneiminebenzoquinone" RELATED [ChemIDplus] synonym: "2,5-di(ethyleneimino)-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "2,5-diaziridinyl-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "3,6-diaziridinyl-1,4-benzoquinone" RELATED [ChEBI] synonym: "DZQ" RELATED [ChEBI] synonym: "ethylenimine quinone" RELATED [ChemIDplus] synonym: "TW 13" RELATED [ChemIDplus] xref: Beilstein:169182 {source="Beilstein"} xref: CAS:526-62-5 {source="ChemIDplus"} xref: PMID:10373575 {source="Europe PMC"} xref: PMID:10978162 {source="Europe PMC"} xref: PMID:11211879 {source="Europe PMC"} xref: PMID:13415397 {source="Europe PMC"} xref: PMID:17094478 {source="Europe PMC"} xref: PMID:1751490 {source="Europe PMC"} xref: PMID:8137269 {source="Europe PMC"} xref: PMID:8461296 {source="Europe PMC"} xref: PMID:9690517 {source="Europe PMC"} xref: Reaxys:169182 {source="Reaxys"} is_a: CHEBI:132124 ! 1,4-benzoquinones is_a: CHEBI:22681 ! aziridines is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000571 ! 2,5-bis(ethyleneimino)-1,4-benzoquinone equivalent_to: FBcv:0000571 ! 2,5-bis(ethyleneimino)-1,4-benzoquinone relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H10N2O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H10N2O2/c13-9-6-8(12-3-4-12)10(14)5-7(9)11-1-2-11/h5-6H,1-4H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RCWJMKCTHJPXJV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "190.19868" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "190.07423" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C1C=C(N2CC2)C(=O)C=C1N1CC1" xsd:string [Term] id: CHEBI:19508 name: 2-chloroethyl methanesulfonate namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:25223 ! methanesulfonate ester is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000528 ! 2-chloroethyl methanesulfonate equivalent_to: FBcv:0000528 ! 2-chloroethyl methanesulfonate relationship: has_role CHEBI:22333 ! alkylating agent [Term] id: CHEBI:19579 name: 2-fluoroethyl methanesulfonate namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:25223 ! methanesulfonate ester is_a: CHEBI:37143 ! organofluorine compound is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000529 ! 2-fluoroethyl methanesulfonate equivalent_to: FBcv:0000529 ! 2-fluoroethyl methanesulfonate relationship: has_role CHEBI:22333 ! alkylating agent [Term] id: CHEBI:20552 name: 5-bromouracil namespace: chebi_ontology def: "A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen." [] subset: 3_STAR synonym: "1,2,3,4-tetrahydro-5-bromo-2,4-pyrimidinedione" RELATED [NIST_Chemistry_WebBook] synonym: "5-bromo-2,4(1H,3H)-pyrimidinedione" RELATED [NIST_Chemistry_WebBook] synonym: "5-bromopyrimidine-2,4(1H,3H)-dione" EXACT IUPAC_NAME [IUPAC] synonym: "5-BrU" RELATED [ChemIDplus] synonym: "5-BU" RELATED [ChemIDplus] synonym: "bromouracil" RELATED [ChemIDplus] xref: Beilstein:127176 {source="Beilstein"} xref: CAS:51-20-7 {source="ChemIDplus"} xref: CAS:51-20-7 {source="NIST Chemistry WebBook"} xref: Gmelin:486432 {source="Gmelin"} xref: PMID:14522043 {source="Europe PMC"} xref: PMID:28166217 {source="Europe PMC"} xref: PMID:28320905 {source="Europe PMC"} xref: PMID:3950402 {source="Europe PMC"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:39447 ! pyrimidines is_a: CHEBI:67142 ! nucleobase analogue is_a: FBcv:0000548 ! base analog is_a: FBcv:0000549 ! 5-bromouracil equivalent_to: FBcv:0000549 ! 5-bromouracil relationship: has_functional_parent CHEBI:17568 ! uracil relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H3BrN2O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H3BrN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LQLQRFGHAALLLE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "190.98300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "189.93779" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Brc1c[nH]c(=O)[nH]c1=O" xsd:string [Term] id: CHEBI:20553 name: 5-bromouridine namespace: chebi_ontology def: "A uridine having a bromo substituent at the 5-position." [] subset: 3_STAR synonym: "1-beta-ribofuranosyl-5-bromo-uracil" RELATED [ChemIDplus] synonym: "5-bromo-1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione" RELATED [ChEBI] synonym: "5-bromouridine" EXACT [UniProt] synonym: "5-bromouridine" EXACT IUPAC_NAME [IUPAC] synonym: "5-bromouridine" EXACT [ChEBI] synonym: "BrU" RELATED [ChEBI] xref: Beilstein:33664 {source="Beilstein"} xref: CAS:957-75-5 {source="ChemIDplus"} xref: Gmelin:723432 {source="Gmelin"} xref: PMID:3950402 {source="Europe PMC"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:27242 ! uridines is_a: CHEBI:67142 ! nucleobase analogue is_a: FBcv:0000548 ! base analog is_a: FBcv:0000550 ! 5-bromouridine equivalent_to: FBcv:0000550 ! 5-bromouridine relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H11BrN2O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11BrN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "AGFIRQJZCNVMCW-UAKXSSHOSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "323.09752" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "321.98005" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c(=O)[nH]c1=O" xsd:string [Term] id: CHEBI:20702 name: 2-aminopurines namespace: chebi_ontology def: "Any aminopurine having the amino substituent at the 2-position." [] subset: 3_STAR synonym: "2-aminopurines" EXACT [ChEBI] is_a: CHEBI:22527 ! aminopurine [Term] id: CHEBI:20787 name: 7-bromomethyl-12-methyltetraphene namespace: chebi_ontology def: "A member of the class of tetraphenes that is tetraphene in which the hydrogens at positions 7 and 12 are replaced by bromomethyl and methyl groups, respectively." [] subset: 3_STAR synonym: "7-(bromomethyl)-12-methyltetraphene" EXACT IUPAC_NAME [IUPAC] synonym: "7-BrMe-12-MeBA" RELATED [ChEBI] synonym: "7-bromomethyl-12-methylbenz[a]anthracene" RELATED [ChemIDplus] synonym: "7-bromomethyl-12-methylbenzanthracene" RELATED [ChemIDplus] xref: Beilstein:2056479 {source="Beilstein"} xref: CAS:16238-56-5 {source="ChemIDplus"} xref: PMID:10838135 {source="Europe PMC"} xref: PMID:3114533 {source="Europe PMC"} xref: PMID:8625451 {source="Europe PMC"} xref: Reaxys:2056479 {source="Reaxys"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:37141 ! organobromine compound is_a: CHEBI:51067 ! tetraphenes is_a: FBcv:0000572 ! 7-bromomethyl-12-methylbenz[a]anthracene equivalent_to: FBcv:0000572 ! 7-bromomethyl-12-methylbenz[a]anthracene relationship: has_parent_hydride CHEBI:51348 ! tetraphene relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C20H15Br" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C20H15Br/c1-13-15-7-4-5-9-17(15)19(12-21)18-11-10-14-6-2-3-8-16(14)20(13)18/h2-11H,12H2,1H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IBWBDNBSIFGSLW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "335.23710" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "334.03571" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cc1c2ccccc2c(CBr)c2ccc3ccccc3c12" xsd:string [Term] id: CHEBI:21183 name: ICR-170 namespace: chebi_ontology subset: 3_STAR synonym: "acridine mustard" RELATED [ChemIDplus] synonym: "ICR 170" RELATED [ChemIDplus] synonym: "N-(2-chloroethyl)-N'-(6-chloro-2-methoxy-9-acridinyl)-N-ethyl-1,3-propanediamine dihydrochloride" RELATED [ChemIDplus] synonym: "N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine dihydrochloride" EXACT IUPAC_NAME [IUPAC] xref: CAS:146-59-8 {source="ChemIDplus"} is_a: CHEBI:22213 ! acridines is_a: FBcv:0000541 ! intercalating agent is_a: FBcv:0000544 ! ICR 170 equivalent_to: FBcv:0000544 ! ICR 170 relationship: has_part CHEBI:37594 ! N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine relationship: has_role CHEBI:24853 ! intercalator property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H27Cl4N3O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C21H25Cl2N3O.2ClH/c1-3-26(12-9-22)11-4-10-24-21-17-7-5-15(23)13-20(17)25-19-8-6-16(27-2)14-18(19)21;;/h5-8,13-14H,3-4,9-12H2,1-2H3,(H,24,25);2*1H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "PWGOWIIEVDAYTC-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "479.26950" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "477.09082" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cl[H].Cl[H].CCN(CCCl)CCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12" xsd:string [Term] id: CHEBI:21184 name: Janus Green B chloride namespace: chebi_ontology subset: 3_STAR synonym: "3-(diethylamino)-7-((4-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride" RELATED [ChemIDplus] synonym: "3-(diethylamino)-7-((p-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride" RELATED [ChemIDplus] synonym: "3-(diethylamino)-7-{(E)-[4-(dimethylamino)phenyl]diazenyl}-5-phenylphenazin-5-ium chloride" EXACT IUPAC_NAME [IUPAC] synonym: "Janus Green B" RELATED [ChemIDplus] synonym: "Janus Green V" RELATED [ChemIDplus] xref: Beilstein:9748061 {source="Beilstein"} xref: CAS:2869-83-2 {source="ChemIDplus"} xref: Patent:US2882209 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:36094 ! organic chloride salt is_a: FBcv:0000589 ! Janus green B equivalent_to: FBcv:0000589 ! Janus green B relationship: has_part CHEBI:51070 ! Janus Green B cation relationship: has_role CHEBI:37958 ! dye property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C30H31ClN6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C30H31N6.ClH/c1-5-35(6-2)26-17-19-28-30(21-26)36(25-10-8-7-9-11-25)29-20-23(14-18-27(29)31-28)33-32-22-12-15-24(16-13-22)34(3)4;/h7-21H,5-6H2,1-4H3;1H/q+1;/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XXACTDWGHQXLGW-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "511.06028" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "510.22987" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Cl-].CCN(CC)c1ccc2nc3ccc(cc3[n+](-c3ccccc3)c2c1)\\N=N\\c1ccc(cc1)N(C)C" xsd:string [Term] id: CHEBI:21644 name: N-acyl-L-amino acid namespace: chebi_ontology def: "Any N-acylamino acid having L-configuration." [] subset: 3_STAR is_a: CHEBI:51569 ! N-acyl-amino acid relationship: is_enantiomer_of CHEBI:15778 ! N-acyl-D-amino acid [Term] id: CHEBI:21731 name: N-glycosyl compound namespace: chebi_ontology def: "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond." [] subset: 3_STAR synonym: "glycosylamine" EXACT IUPAC_NAME [IUPAC] synonym: "glycosylamines" RELATED [IUPAC] synonym: "N-glycoside" RELATED [ChEBI] synonym: "N-glycosides" RELATED [ChEBI] synonym: "N-glycosyl compounds" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:63161 ! glycosyl compound [Term] id: CHEBI:21759 name: N-methyl-N'-nitro-N-nitrosoguanidine namespace: chebi_ontology alt_id: CHEBI:34872 def: "An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position" [] subset: 3_STAR synonym: "1-Methyl-1-nitroso-3-nitroguanidine" RELATED [ChemIDplus] synonym: "1-Methyl-3-nitro-1-nitrosoguanidine" RELATED [KEGG_COMPOUND] synonym: "1-methyl-3-nitro-1-nitrosoguanidine" EXACT IUPAC_NAME [IUPAC] synonym: "1-Nitroso-3-nitro-1-methylguanidine" RELATED [ChemIDplus] synonym: "Methylnitronitrosoguanidine" RELATED [KEGG_COMPOUND] synonym: "MNG" RELATED [ChemIDplus] synonym: "MNNG" RELATED [KEGG_COMPOUND] synonym: "MNNG" RELATED [ChemIDplus] synonym: "N'-Nitro-N-nitroso-N-methylguanidine" RELATED [ChemIDplus] synonym: "N-Methyl-N',2-dioxohydrazinecarboximidohydrazide 2-oxide" RELATED [NIST_Chemistry_WebBook] synonym: "N-Methyl-N'-nitro-N-nitrosoguanidine" EXACT [KEGG_COMPOUND] synonym: "N-Methyl-N-nitroso-N'-nitroguanidine" RELATED [ChEBI] synonym: "N-Methyl-N-nitroso-N'-nitroguanidine" RELATED [ChemIDplus] synonym: "N-Methyl-N-nitrosonitroguanidin" RELATED [ChEBI] synonym: "N-Nitroso-N-methyl-N'-nitroguanidine" RELATED [ChemIDplus] xref: Beilstein:1779490 {source="Beilstein"} xref: CAS:70-25-7 {source="NIST Chemistry WebBook"} xref: CAS:70-25-7 {source="KEGG COMPOUND"} xref: CAS:70-25-7 {source="ChemIDplus"} xref: KEGG:C14592 is_a: CHEBI:35800 ! nitroso compound is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000535 ! N-methyl-N'-nitro-N-nitrosoguanidine equivalent_to: FBcv:0000535 ! N-methyl-N'-nitro-N-nitrosoguanidine relationship: has_functional_parent CHEBI:39179 ! nitroguanidine relationship: has_role CHEBI:22333 ! alkylating agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H5N5O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5N5O3/c1-6(5-8)2(3)4-7(9)10/h1H3,(H2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "VZUNGTLZRAYYDE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "147.09280" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "147.03924" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CN(N=O)C(=N)N[N+]([O-])=O" xsd:string [Term] id: CHEBI:22025 name: S-2-chloroethylcysteine namespace: chebi_ontology subset: 1_STAR is_a: BFO:0000004 ! independent continuant is_a: CHEBI:23509 ! cysteine derivative is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000602 ! S-2-chloroethylcysteine equivalent_to: FBcv:0000602 ! S-2-chloroethylcysteine relationship: has_role CHEBI:25435 ! mutagen [Term] id: CHEBI:22063 name: sulfoxide namespace: chebi_ontology alt_id: CHEBI:35813 def: "An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H)." [] subset: 3_STAR synonym: "S-oxides" RELATED [ChEBI] synonym: "sulfoxide" EXACT [ChEBI] synonym: "sulfoxides" RELATED [ChEBI] is_a: CHEBI:33261 ! organosulfur compound [Term] id: CHEBI:22160 name: acetamides namespace: chebi_ontology def: "Compounds with the general formula RNHC(=O)CH3." [] subset: 3_STAR is_a: CHEBI:37622 ! carboxamide [Term] id: CHEBI:22213 name: acridines namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:39206 ! dibenzopyridine [Term] id: CHEBI:22221 name: acyl group namespace: chebi_ontology def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." [] subset: 3_STAR synonym: "acyl group" EXACT [IUPAC] synonym: "acyl groups" RELATED [ChEBI] synonym: "alkanoyl" EXACT IUPAC_NAME [IUPAC] synonym: "alkanoyl group" RELATED [ChEBI] synonym: "groupe acyle" RELATED [IUPAC] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:22314 name: alkali metal atom namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal" RELATED [ChEBI] synonym: "alkali metals" EXACT IUPAC_NAME [IUPAC] synonym: "Alkalimetall" RELATED [ChEBI] synonym: "Alkalimetalle" RELATED [ChEBI] synonym: "metal alcalin" RELATED [ChEBI] synonym: "metal alcalino" RELATED [ChEBI] synonym: "metales alcalinos" RELATED [ChEBI] synonym: "metaux alcalins" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom is_a: CHEBI:33521 ! metal atom is_a: CHEBI:33559 ! s-block element atom [Term] id: CHEBI:22315 name: alkaloid namespace: chebi_ontology def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." [] subset: 3_STAR synonym: "alcaloide" RELATED [ChEBI] synonym: "alcaloides" RELATED [ChEBI] synonym: "Alkaloid" EXACT [ChEBI] synonym: "Alkaloide" RELATED [ChEBI] synonym: "alkaloids" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Alkaloid is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35352 ! organonitrogen compound relationship: has_role CHEBI:25212 ! metabolite [Term] id: CHEBI:22323 name: alkyl group namespace: chebi_ontology def: "A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom." [] subset: 3_STAR synonym: "alkyl group" EXACT IUPAC_NAME [IUPAC] synonym: "alkyl groups" EXACT IUPAC_NAME [IUPAC] synonym: "groupe alkyle" RELATED [IUPAC] synonym: "grupo alquilo" RELATED [IUPAC] synonym: "grupos alquilo" RELATED [IUPAC] is_a: CHEBI:33248 ! hydrocarbyl group relationship: is_substituent_group_from CHEBI:18310 ! alkane [Term] id: CHEBI:22327 name: aliphatic sulfide namespace: chebi_ontology subset: 3_STAR synonym: "aliphatic thioether" RELATED [ChEBI] synonym: "aliphatic thioethers" RELATED [ChEBI] is_a: CHEBI:16385 ! organic sulfide [Term] id: CHEBI:22333 name: alkylating agent namespace: chebi_ontology def: "Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases." [] subset: 3_STAR is_a: CHEBI:25435 ! mutagen [Term] id: CHEBI:22494 name: aminobenzoate namespace: chebi_ontology subset: 3_STAR synonym: "aminobenzoates" RELATED [ChEBI] is_a: CHEBI:22718 ! benzoates [Term] id: CHEBI:22526 name: 4-aminofolic acid namespace: chebi_ontology subset: 3_STAR synonym: "4-amino-PGA" RELATED [ChemIDplus] synonym: "4-aminofolic acid" EXACT [ChemIDplus] synonym: "4-aminopteroylglutamic acid" RELATED [ChemIDplus] synonym: "aminopterin" RELATED [ChemIDplus] synonym: "N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid" RELATED [ChemIDplus] synonym: "N-(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:69045 {source="Beilstein"} xref: CAS:54-62-6 {source="ChemIDplus"} xref: Drug_Central:21 {source="DrugCentral"} xref: PMID:18789931 {source="Europe PMC"} is_a: CHEBI:35692 ! dicarboxylic acid is_a: FBcv:0000551 ! enzyme inhibitor is_a: FBcv:0000552 ! aminopterin equivalent_to: FBcv:0000552 ! aminopterin relationship: has_functional_parent CHEBI:27470 ! folic acid relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:50683 ! EC 1.5.1.3 (dihydrofolate reductase) inhibitor property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H20N8O5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)/t12-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "TVZGACDUOSZQKY-LBPRGKRZSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "440.41302" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "440.15567" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1" xsd:string [Term] id: CHEBI:22527 name: aminopurine namespace: chebi_ontology def: "Any purine having at least one amino substituent." [] subset: 3_STAR synonym: "aminopurines" RELATED [ChEBI] is_a: CHEBI:26401 ! purines [Term] id: CHEBI:22563 name: anion namespace: chebi_ontology def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." [] subset: 3_STAR synonym: "Anion" EXACT [ChEBI] synonym: "anion" EXACT IUPAC_NAME [IUPAC] synonym: "anion" EXACT [ChEBI] synonym: "Anionen" RELATED [ChEBI] synonym: "aniones" RELATED [ChEBI] synonym: "anions" RELATED [IUPAC] is_a: CHEBI:24870 ! ion [Term] id: CHEBI:22586 name: antioxidant namespace: chebi_ontology def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." [] subset: 3_STAR synonym: "antioxidants" RELATED [ChEBI] synonym: "antioxydant" RELATED [ChEBI] synonym: "antoxidant" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22587 name: antiviral agent namespace: chebi_ontology def: "A substance that destroys or inhibits replication of viruses." [] subset: 3_STAR synonym: "anti-viral agent" RELATED [ChEBI] synonym: "anti-viral agents" RELATED [ChEBI] synonym: "antiviral" RELATED [ChEBI] synonym: "antiviral agents" RELATED [ChEBI] synonym: "antivirals" RELATED [ChEBI] is_a: CHEBI:33281 ! antimicrobial agent [Term] id: CHEBI:22681 name: aziridines namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:25693 ! organic heteromonocyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:22695 name: base namespace: chebi_ontology def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." [] subset: 3_STAR synonym: "Base" EXACT [ChEBI] synonym: "base" EXACT [ChEBI] synonym: "base" EXACT IUPAC_NAME [IUPAC] synonym: "Base1" RELATED [KEGG_COMPOUND] synonym: "Base2" RELATED [KEGG_COMPOUND] synonym: "Basen" RELATED [ChEBI] synonym: "bases" RELATED [ChEBI] synonym: "Nucleobase" RELATED [KEGG_COMPOUND] xref: KEGG:C00701 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22712 name: benzenes namespace: chebi_ontology def: "Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives." [] subset: 3_STAR is_a: CHEBI:33836 ! benzenoid aromatic compound [Term] id: CHEBI:22713 name: arenesulfonate oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "arenesulfonates" RELATED [ChEBI] is_a: CHEBI:33554 ! organosulfonate oxoanion relationship: is_conjugate_base_of CHEBI:33555 ! arenesulfonic acid [Term] id: CHEBI:22718 name: benzoates namespace: chebi_ontology def: "A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid." [] subset: 3_STAR synonym: "benzoate anion" RELATED [ChEBI] is_a: CHEBI:35757 ! monocarboxylic acid anion [Term] id: CHEBI:22727 name: benzopyran namespace: chebi_ontology subset: 3_STAR synonym: "benzopyrans" RELATED [ChEBI] xref: Wikipedia:Benzopyran is_a: CHEBI:38104 ! oxacycle is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:22729 name: benzoquinones namespace: chebi_ontology def: "Any quinone resulting from the formal oxidation of catechol, hydroquinone, or their C-substituted derivatives." [] subset: 3_STAR is_a: CHEBI:36141 ! quinone [Term] id: CHEBI:22744 name: benzyl group namespace: chebi_ontology subset: 3_STAR synonym: "benzyl" EXACT IUPAC_NAME [IUPAC] synonym: "Bn" RELATED [ChEBI] synonym: "C6H5-CH2-" RELATED [IUPAC] synonym: "phenylalanine side-chain" RELATED [ChEBI] synonym: "phenylmethyl" RELATED [IUPAC] is_a: CHEBI:33452 ! benzylic group is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group relationship: is_substituent_group_from CHEBI:17578 ! toluene property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H7" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "91.13048" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "91.05478" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=C(C=CC=C1)C*" xsd:string [Term] id: CHEBI:22908 name: borate namespace: chebi_ontology subset: 3_STAR synonym: "(BO3)3-" RELATED [ChEBI] synonym: "[BO3](3-)" RELATED [IUPAC] synonym: "BO3(3-)" RELATED [IUPAC] synonym: "borate" EXACT IUPAC_NAME [IUPAC] synonym: "borate ion" RELATED [ChEBI] synonym: "trioxidoborate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "trioxoborate(3-) ion" RELATED [ChEBI] synonym: "trioxoborate(III) anion" RELATED [ChEBI] xref: Gmelin:164057 {source="Gmelin"} is_a: CHEBI:22909 ! borate ion relationship: is_conjugate_base_of CHEBI:29255 ! hydrogenborate property_value: http://purl.obolibrary.org/obo/chebi/charge "-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "BO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/BO3/c2-1(3)4/q-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BTBUEUYNUDRHOZ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "58.80920" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "58.99569" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]B([O-])[O-]" xsd:string [Term] id: CHEBI:22909 name: borate ion namespace: chebi_ontology def: "Any inorganic anion that is formally derived from boric acid. The term includes polymeric anions containing chains of BO3 structural units sharing one oxygen atom (e.g. di-, tri-, and tetraborates) as well as chains or rings sharing two oxygen atoms (e.g. metaborates)." [] subset: 3_STAR synonym: "borate anions" RELATED [ChEBI] synonym: "borate ion" EXACT [ChEBI] synonym: "borate ions" RELATED [ChEBI] xref: Wikipedia:Borate is_a: CHEBI:24834 ! inorganic anion is_a: CHEBI:33619 ! boron oxoanion [Term] id: CHEBI:22916 name: boron molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "boron compounds" RELATED [ChEBI] synonym: "boron molecular entities" RELATED [ChEBI] synonym: "boron molecular entity" EXACT [ChEBI] is_a: CHEBI:33581 ! boron group molecular entity relationship: has_part CHEBI:27560 ! boron atom [Term] id: CHEBI:22926 name: bromohydrocarbon namespace: chebi_ontology def: "A compound derived from a hydrocarbon by replacing a hydrogen atom with a bromine atom." [] subset: 3_STAR synonym: "brominated hydrocarbons" RELATED [ChEBI] synonym: "bromohydrocarbons" RELATED [ChEBI] is_a: CHEBI:24472 ! halohydrocarbon is_a: CHEBI:37141 ! organobromine compound [Term] id: CHEBI:22927 name: bromine atom namespace: chebi_ontology subset: 3_STAR synonym: "35Br" RELATED [IUPAC] synonym: "Br" RELATED [ChEBI] synonym: "Brom" RELATED [ChEBI] synonym: "brome" RELATED [ChEBI] synonym: "bromine" EXACT IUPAC_NAME [IUPAC] synonym: "bromine" RELATED [ChEBI] synonym: "bromo" RELATED [ChEBI] synonym: "bromum" RELATED [ChEBI] xref: WebElements:Br is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24473 ! halogen relationship: has_role CHEBI:27027 ! micronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Br" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Br" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WKBOTKDWSSQWDR-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "79.90400" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "78.91834" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Br]" xsd:string [Term] id: CHEBI:22928 name: bromine molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "bromine compounds" RELATED [ChEBI] synonym: "bromine molecular entities" RELATED [ChEBI] synonym: "bromine molecular entity" EXACT [ChEBI] is_a: CHEBI:24471 ! halogen molecular entity relationship: has_part CHEBI:22927 ! bromine atom [Term] id: CHEBI:22929 name: bromoalkane namespace: chebi_ontology def: "Any haloalkane that consists of an alkane substituted by at least one bromine atom." [] subset: 3_STAR synonym: "alkyl bromide" RELATED [ChEBI] synonym: "alkyl bromides" RELATED [ChEBI] synonym: "bromoalkanes" RELATED [ChEBI] is_a: CHEBI:24469 ! haloalkane is_a: CHEBI:37141 ! organobromine compound [Term] id: CHEBI:22944 name: butanediols namespace: chebi_ontology def: "A diol that is a butanediol or a derivative of a butanediol." [] subset: 3_STAR is_a: CHEBI:23824 ! diol [Term] id: CHEBI:23003 name: carbamate ester namespace: chebi_ontology def: "Any ester of carbamic acid or its N-substituted derivatives." [] subset: 3_STAR synonym: "carbamate esters" RELATED [ChEBI] synonym: "carbamates" RELATED [ChEBI] xref: Wikipedia:Carbamate is_a: CHEBI:33308 ! carboxylic ester relationship: has_functional_parent CHEBI:28616 ! carbamic acid [Term] id: CHEBI:23004 name: carbamoyl group namespace: chebi_ontology def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." [] subset: 3_STAR synonym: "-C(O)NH2" RELATED [ChEBI] synonym: "-CONH2" RELATED [IUPAC] synonym: "aminocarbonyl" RELATED [IUPAC] synonym: "carbamoyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbamyl" RELATED [ChEBI] synonym: "carbamyl group" RELATED [ChEBI] synonym: "carboxamide" RELATED [IUPAC] xref: PMID:24168430 {source="Europe PMC"} is_a: CHEBI:27207 ! univalent carboacyl group relationship: is_substituent_group_from CHEBI:28616 ! carbamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.03272" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.01364" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(N)=O" xsd:string [Term] id: CHEBI:23019 name: carbonyl group namespace: chebi_ontology subset: 3_STAR synonym: ">C=O" RELATED [IUPAC] synonym: "carbonyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbonyl group" EXACT [ChEBI] synonym: "carbonyl group" EXACT [UniProt] is_a: CHEBI:51422 ! organodiyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "28.01010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C(*)*" xsd:string [Term] id: CHEBI:23092 name: chemosterilant namespace: chebi_ontology def: "A substance intended to sterilize any organism." [] subset: 3_STAR synonym: "chemosterilants" RELATED [ChEBI] xref: Wikipedia:Chemosterilant is_a: CHEBI:25944 ! pesticide [Term] id: CHEBI:23114 name: chloride salt namespace: chebi_ontology subset: 3_STAR synonym: "chloride salts" RELATED [ChEBI] synonym: "chlorides" RELATED [ChEBI] is_a: CHEBI:23117 ! chlorine molecular entity is_a: CHEBI:33958 ! halide salt relationship: has_part CHEBI:17996 ! chloride [Term] id: CHEBI:23116 name: chlorine atom namespace: chebi_ontology subset: 3_STAR synonym: "17Cl" RELATED [IUPAC] synonym: "Chlor" RELATED [ChEBI] synonym: "chlore" RELATED [ChEBI] synonym: "chlorine" EXACT IUPAC_NAME [IUPAC] synonym: "chlorine" RELATED [ChEBI] synonym: "chlorum" RELATED [ChEBI] synonym: "Cl" RELATED [IUPAC] synonym: "cloro" RELATED [ChEBI] xref: WebElements:Cl is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24473 ! halogen relationship: has_role CHEBI:27027 ! micronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Cl" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Cl" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ZAMOUSCENKQFHK-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "35.45270" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "34.96885" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Cl]" xsd:string [Term] id: CHEBI:23117 name: chlorine molecular entity namespace: chebi_ontology def: "A halogen molecular entity containing one or more atoms of chlorine." [] subset: 3_STAR is_a: CHEBI:24471 ! halogen molecular entity relationship: has_part CHEBI:23116 ! chlorine atom [Term] id: CHEBI:23128 name: chloroalkane namespace: chebi_ontology def: "Any haloalkane that consists of an alkane substituted by at least one chloro group." [] subset: 3_STAR synonym: "alkyl chloride" RELATED [ChEBI] synonym: "alkyl chlorides" RELATED [ChEBI] synonym: "chloroalkane" EXACT [ChEBI] synonym: "chloroalkanes" RELATED [ChEBI] is_a: CHEBI:24469 ! haloalkane is_a: CHEBI:36683 ! organochlorine compound [Term] id: CHEBI:23239 name: chromopeptide namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:25903 ! peptide antibiotic [Term] id: CHEBI:23357 name: cofactor namespace: chebi_ontology def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." [] subset: 3_STAR synonym: "cofactor" EXACT [IUPAC] synonym: "cofactors" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Cofactor_(biochemistry) is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:23359 name: colchicine namespace: chebi_ontology def: "An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum." [] subset: 3_STAR synonym: "N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:2228812 {source="Beilstein"} xref: CAS:54192-66-4 {source="NIST Chemistry WebBook"} xref: DrugBank:DB01394 xref: HMDB:HMDB0015466 xref: LINCS:LSM-6449 xref: PMID:10680067 {source="Europe PMC"} xref: PMID:24074178 {source="Europe PMC"} xref: PMID:7200520 {source="Europe PMC"} xref: PMID:9819133 {source="Europe PMC"} xref: Reaxys:2228812 {source="Reaxys"} is_a: CHEBI:22160 ! acetamides is_a: CHEBI:22315 ! alkaloid is_a: CHEBI:35618 ! aromatic ether is_a: CHEBI:38032 ! carbotricyclic compound is_a: FBcv:0000577 ! colchicine equivalent_to: FBcv:0000577 ! colchicine relationship: has_role CHEBI:61951 ! microtubule-destabilising agent relationship: has_role CHEBI:76924 ! plant metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C22H25NO6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IAKHMKGGTNLKSZ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "399.43704" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "399.16819" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COc1cc2CCC(NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC" xsd:string [Term] id: CHEBI:23367 name: molecular entity namespace: chebi_ontology def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." [] subset: 3_STAR synonym: "entidad molecular" RELATED [IUPAC] synonym: "entidades moleculares" RELATED [IUPAC] synonym: "entite moleculaire" RELATED [IUPAC] synonym: "molecular entities" RELATED [IUPAC] synonym: "molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "molekulare Entitaet" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical [Term] id: CHEBI:23377 name: copper molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "copper compounds" RELATED [ChEBI] synonym: "copper molecular entities" RELATED [ChEBI] synonym: "copper molecular entity" EXACT [ChEBI] is_a: CHEBI:33745 ! copper group molecular entity relationship: has_part CHEBI:28694 ! copper atom [Term] id: CHEBI:23378 name: copper cation namespace: chebi_ontology subset: 3_STAR synonym: "copper cation" EXACT IUPAC_NAME [IUPAC] synonym: "copper cations" RELATED [ChEBI] synonym: "Cu cation" RELATED [UniProt] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33515 ! transition element cation is_a: CHEBI:37404 ! elemental copper relationship: has_role CHEBI:23357 ! cofactor property_value: http://purl.obolibrary.org/obo/chebi/formula "Cu" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "63.546" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.92960" xsd:string [Term] id: CHEBI:23414 name: copper(II) sulfate namespace: chebi_ontology def: "A metal sulfate compound having copper(2+) as the metal ion." [] subset: 3_STAR synonym: "copper sulfate" RELATED [ChemIDplus] synonym: "copper(2+) sulfate" EXACT IUPAC_NAME [IUPAC] synonym: "Copper(II) sulfate" EXACT [KEGG_COMPOUND] synonym: "copper(II) sulfate" EXACT IUPAC_NAME [IUPAC] synonym: "Cupric sulfate" RELATED [ChemIDplus] synonym: "cupric sulfate anhydrous" RELATED [ChemIDplus] synonym: "CuSO4" RELATED [IUPAC] xref: CAS:7758-98-7 {source="ChemIDplus"} xref: CAS:7758-98-7 {source="KEGG COMPOUND"} xref: Gmelin:8294 {source="Gmelin"} xref: KEGG:C18713 xref: PMID:10469300 {source="Europe PMC"} xref: PMID:29079364 {source="Europe PMC"} xref: PMID:8566016 {source="Europe PMC"} xref: PPDB:178 xref: Wikipedia:Copper(II)_sulfate is_a: BFO:0000004 ! independent continuant is_a: CHEBI:51336 ! metal sulfate is_a: FBcv:0000554 ! cupric sulfate equivalent_to: FBcv:0000554 ! cupric sulfate relationship: has_part CHEBI:29036 ! copper(2+) relationship: has_role CHEBI:139492 ! sensitiser relationship: has_role CHEBI:149552 ! emetic relationship: has_role CHEBI:33287 ! fertilizer property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CuO4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Cu.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ARUVKPQLZAKDPS-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "159.60960" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "158.88133" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Cu++].[O-]S([O-])(=O)=O" xsd:string [Term] id: CHEBI:23509 name: cysteine derivative namespace: chebi_ontology alt_id: CHEBI:25309 def: "An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues." [] subset: 3_STAR synonym: "cysteine derivative" EXACT [ChEBI] synonym: "cysteine derivatives" RELATED [ChEBI] is_a: CHEBI:83821 ! amino acid derivative relationship: has_functional_parent CHEBI:15356 ! cysteine [Term] id: CHEBI:23636 name: deoxyribonucleoside namespace: chebi_ontology subset: 3_STAR synonym: "deoxyribonucleosides" RELATED [ChEBI] is_a: CHEBI:33838 ! nucleoside [Term] id: CHEBI:23704 name: diepoxybutane namespace: chebi_ontology subset: 3_STAR synonym: "1,1'-bi[ethylene oxide]" RELATED [NIST_Chemistry_WebBook] synonym: "1,2:3,4-butadiene diepoxide" RELATED [ChemIDplus] synonym: "1,2:3,4-dianhydrothreitol" RELATED [NIST_Chemistry_WebBook] synonym: "1,2:3,4-diepoxybutane" RELATED [ChemIDplus] synonym: "1,3-butadiene diepoxide" RELATED [NIST_Chemistry_WebBook] synonym: "2,2'-bioxirane" EXACT IUPAC_NAME [IUPAC] synonym: "bioxirane" RELATED [NIST_Chemistry_WebBook] synonym: "Butadiendioxyd" RELATED [ChemIDplus] synonym: "butadiene diepoxide" RELATED [NIST_Chemistry_WebBook] synonym: "butadiene dioxide" RELATED [NIST_Chemistry_WebBook] synonym: "butane diepoxide" RELATED [NIST_Chemistry_WebBook] synonym: "DEB" RELATED [NIST_Chemistry_WebBook] synonym: "dioxybutadiene" RELATED [ChemIDplus] xref: Beilstein:79831 {source="Beilstein"} xref: CAS:1464-53-5 {source="NIST Chemistry WebBook"} xref: CAS:1464-53-5 {source="ChemIDplus"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:32955 ! epoxide is_a: FBcv:0000558 ! epoxy hydrocarbon is_a: FBcv:0000559 ! diepoxybutane equivalent_to: FBcv:0000559 ! diepoxybutane relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H6O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H6O2/c1-3(5-1)4-2-6-4/h3-4H,1-2H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ZFIVKAOQEXOYFY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "86.08924" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "86.03678" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1OC1C1CO1" xsd:string [Term] id: CHEBI:23705 name: 1,2:7,8-diepoxyoctane namespace: chebi_ontology subset: 3_STAR synonym: "1,2,7,8-Diepoxyoctane" RELATED [ChemIDplus] synonym: "1,2-Epoxy-7,8-epoxyoctane" RELATED [ChemIDplus] synonym: "1,7-Octadiene diepoxide" RELATED [ChemIDplus] synonym: "2,2'-(1,4-Butanediyl)bisoxirane" RELATED [ChemIDplus] synonym: "2,2'-butane-1,4-diyldioxirane" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:104873 {source="Beilstein"} xref: CAS:2426-07-5 {source="ChemIDplus"} xref: CAS:2426-07-5 {source="NIST Chemistry WebBook"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:32955 ! epoxide is_a: FBcv:0000558 ! epoxy hydrocarbon is_a: FBcv:0000560 ! diepoxyoctane equivalent_to: FBcv:0000560 ! diepoxyoctane relationship: has_parent_hydride CHEBI:17590 ! octane relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H14O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H14O2/c1(3-7-5-9-7)2-4-8-6-10-8/h7-8H,1-6H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LFKLPJRVSHJZPL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "142.19556" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "142.09938" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(CCC1CO1)CC1CO1" xsd:string [Term] id: CHEBI:23824 name: diol namespace: chebi_ontology def: "A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols." [] subset: 3_STAR synonym: "diols" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Diol is_a: CHEBI:26191 ! polyol [Term] id: CHEBI:23888 name: drug namespace: chebi_ontology def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." [] subset: 3_STAR synonym: "drugs" RELATED [ChEBI] synonym: "medicine" RELATED [ChEBI] is_a: CHEBI:52217 ! pharmaceutical [Term] id: CHEBI:23905 name: monoatomic anion namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:24867 ! monoatomic ion [Term] id: CHEBI:23906 name: monoatomic cation namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic cations" RELATED [ChEBI] is_a: CHEBI:24867 ! monoatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:23924 name: enzyme inhibitor namespace: chebi_ontology def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." [] subset: 3_STAR synonym: "enzyme inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "enzyme inhibitors" RELATED [ChEBI] synonym: "inhibidor enzimatico" RELATED [ChEBI] synonym: "inhibidores enzimaticos" RELATED [ChEBI] synonym: "inhibiteur enzymatique" RELATED [ChEBI] synonym: "inhibiteurs enzymatiques" RELATED [ChEBI] is_a: CHEBI:35222 ! inhibitor is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:23994 name: ethyl methanesulfonate namespace: chebi_ontology def: "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol." [] subset: 3_STAR synonym: "EMS" RELATED [ChemIDplus] synonym: "ethyl mesylate" RELATED [ChemIDplus] synonym: "ethyl methanesulphonate" RELATED [ChemIDplus] synonym: "methylsulfonic acid ethyl ester" RELATED [ChemIDplus] synonym: "methylsulfonic acid, ethyl ester" RELATED [ChemIDplus] xref: CAS:62-50-0 {source="KEGG COMPOUND"} xref: CAS:62-50-0 {source="ChemIDplus"} xref: CAS:62-50-0 {source="NIST Chemistry WebBook"} xref: KEGG:C19239 xref: PMID:16039156 {source="Europe PMC"} xref: PMID:19797863 {source="Europe PMC"} xref: PMID:20102787 {source="Europe PMC"} xref: PMID:24475756 {source="Europe PMC"} xref: PMID:24524729 {source="Europe PMC"} xref: PMID:24531730 {source="Europe PMC"} xref: PMID:24728647 {source="Europe PMC"} xref: PMID:6936603 {source="Europe PMC"} xref: PMID:7285888 {source="Europe PMC"} xref: Reaxys:773969 {source="Reaxys"} xref: Wikipedia:Ethyl_methanesulfonate is_a: CHEBI:25223 ! methanesulfonate ester is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000530 ! ethyl methanesulfonate equivalent_to: FBcv:0000530 ! ethyl methanesulfonate relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:35610 ! antineoplastic agent relationship: has_role CHEBI:50902 ! genotoxin relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:50905 ! teratogenic agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H8O3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "PLUBXMRUUVWRLT-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "124.15900" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "124.01942" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCOS(C)(=O)=O" xsd:string [Term] id: CHEBI:23995 name: N-ethyl-N-nitrosourea namespace: chebi_ontology def: "A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups." [] subset: 3_STAR synonym: "1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine" RELATED [NIST_Chemistry_WebBook] synonym: "1-Ethyl-1-nitrosourea" RELATED [ChemIDplus] synonym: "1-ethyl-1-nitrosourea" EXACT IUPAC_NAME [IUPAC] synonym: "Aethylnitroso-harnstoff" RELATED [ChemIDplus] synonym: "ENU" RELATED [ChemIDplus] synonym: "Ethyl nitrosourea" RELATED [ChemIDplus] synonym: "N-Ethyl-N-nitroso carbamide" RELATED [ChemIDplus] synonym: "N-Ethyl-N-nitroso-urea" RELATED [ChemIDplus] synonym: "N-Ethylnitrosourea" RELATED [ChemIDplus] synonym: "NEU" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1761174 {source="Beilstein"} xref: CAS:759-73-9 {source="NIST Chemistry WebBook"} xref: CAS:759-73-9 {source="ChemIDplus"} xref: CAS:759-73-9 {source="KEGG COMPOUND"} xref: KEGG:C19178 xref: PMID:11732210 {source="Europe PMC"} xref: PMID:11853764 {source="Europe PMC"} xref: PMID:11880538 {source="Europe PMC"} xref: PMID:16423555 {source="Europe PMC"} xref: PMID:21861612 {source="Europe PMC"} xref: PMID:22012195 {source="Europe PMC"} xref: PMID:22238669 {source="Europe PMC"} xref: PMID:23551873 {source="Europe PMC"} xref: PMID:24175309 {source="Europe PMC"} xref: PMID:8603364 {source="Europe PMC"} xref: Reaxys:1761174 {source="Reaxys"} xref: Wikipedia:ENU is_a: CHEBI:76551 ! N-nitrosoureas is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000531 ! ethyl nitrosourea equivalent_to: FBcv:0000531 ! ethyl nitrosourea relationship: has_functional_parent CHEBI:16199 ! urea relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:50902 ! genotoxin relationship: has_role CHEBI:50903 ! carcinogenic agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H7N3O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FUSGACRLAFQQRL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "117.10660" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "117.05383" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(N=O)C(N)=O" xsd:string [Term] id: CHEBI:23996 name: ethyl sulfide namespace: chebi_ontology def: "An aliphatic sulfide in which the sulfur atom is bonded to at least one ethyl group." [] subset: 3_STAR synonym: "ethyl sulfides" RELATED [ChEBI] is_a: CHEBI:22327 ! aliphatic sulfide [Term] id: CHEBI:24060 name: fluoride salt namespace: chebi_ontology subset: 3_STAR synonym: "fluoride salts" RELATED [ChEBI] synonym: "fluorides" RELATED [ChEBI] is_a: CHEBI:24062 ! fluorine molecular entity is_a: CHEBI:33958 ! halide salt relationship: has_part CHEBI:17051 ! fluoride [Term] id: CHEBI:24061 name: fluorine atom namespace: chebi_ontology subset: 3_STAR synonym: "9F" RELATED [IUPAC] synonym: "F" RELATED [IUPAC] synonym: "Fluor" RELATED [ChemIDplus] synonym: "fluor" RELATED [ChEBI] synonym: "fluorine" EXACT IUPAC_NAME [IUPAC] synonym: "fluorine" RELATED [ChEBI] synonym: "fluorum" RELATED [ChEBI] xref: CAS:7782-41-4 {source="ChemIDplus"} xref: WebElements:F is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24473 ! halogen relationship: has_role CHEBI:27027 ! micronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "F" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/F" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YCKRFDGAMUMZLT-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "18.99840" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.99840" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[F]" xsd:string [Term] id: CHEBI:24062 name: fluorine molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "fluorine compounds" RELATED [ChEBI] synonym: "fluorine molecular entities" RELATED [ChEBI] synonym: "fluorine molecular entity" EXACT [ChEBI] is_a: CHEBI:24471 ! halogen molecular entity relationship: has_part CHEBI:24061 ! fluorine atom [Term] id: CHEBI:24315 name: glutamic acid derivative namespace: chebi_ontology def: "An amino acid derivative resulting from reaction of glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamic acid residues." [] subset: 3_STAR is_a: CHEBI:83821 ! amino acid derivative relationship: has_functional_parent CHEBI:18237 ! glutamic acid [Term] id: CHEBI:24318 name: glutamine family amino acid namespace: chebi_ontology def: "An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class." [] subset: 3_STAR synonym: "glutamine family amino acids" RELATED [ChEBI] xref: PMID:20716061 {source="Europe PMC"} is_a: CHEBI:15705 ! L-alpha-amino acid is_a: CHEBI:83813 ! proteinogenic amino acid [Term] id: CHEBI:24319 name: EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor namespace: chebi_ontology def: "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2)." [] subset: 3_STAR synonym: "EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors" RELATED [ChEBI] synonym: "EC 6.3.1.2 inhibitor" RELATED [ChEBI] synonym: "EC 6.3.1.2 inhibitors" RELATED [ChEBI] synonym: "glutamate--ammonia ligase (EC 6.3.1.2) inhibitor" RELATED [ChEBI] synonym: "glutamate--ammonia ligase (EC 6.3.1.2) inhibitors" RELATED [ChEBI] synonym: "glutamate--ammonia ligase inhibitor" RELATED [ChEBI] synonym: "glutamate--ammonia ligase inhibitors" RELATED [ChEBI] synonym: "glutamine synthetase inhibitor" RELATED [ChEBI] synonym: "glutamine synthetase inhibitors" RELATED [ChEBI] synonym: "glutamylhydroxamic synthetase inhibitor" RELATED [ChEBI] synonym: "glutamylhydroxamic synthetase inhibitors" RELATED [ChEBI] synonym: "L-glutamate:ammonia ligase (ADP-forming) inhibitor" RELATED [ChEBI] synonym: "L-glutamate:ammonia ligase (ADP-forming) inhibitors" RELATED [ChEBI] synonym: "L-glutamine synthetase inhibitor" RELATED [ChEBI] synonym: "L-glutamine synthetase inhibitors" RELATED [ChEBI] xref: Wikipedia:Glutamine_synthetase is_a: CHEBI:76823 ! EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor [Term] id: CHEBI:24400 name: glycoside namespace: chebi_ontology def: "A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively." [] subset: 3_STAR synonym: "glycosides" EXACT IUPAC_NAME [IUPAC] synonym: "glycosides" RELATED [ChEBI] synonym: "O-glycoside" RELATED [ChEBI] synonym: "O-glycosides" RELATED [ChEBI] is_a: CHEBI:63161 ! glycosyl compound [Term] id: CHEBI:24431 name: chemical entity namespace: chebi_ontology def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." [] subset: 3_STAR synonym: "chemical entity" EXACT [UniProt] is_a: FBcv:0000452 ! origin of mutation is_a: FBcv:0000525 ! chemical equivalent_to: FBcv:0000525 ! chemical [Term] id: CHEBI:24432 name: biological role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a biological context." [] subset: 3_STAR synonym: "biological function" RELATED [ChEBI] is_a: CHEBI:50906 ! role [Term] id: CHEBI:24433 name: group namespace: chebi_ontology def: "A defined linked collection of atoms or a single atom within a molecular entity." [] subset: 3_STAR synonym: "group" EXACT IUPAC_NAME [IUPAC] synonym: "groupe" RELATED [IUPAC] synonym: "grupo" RELATED [IUPAC] synonym: "grupos" RELATED [IUPAC] synonym: "Gruppe" RELATED [ChEBI] synonym: "Rest" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical relationship: has_part CHEBI:33250 ! atom [Term] id: CHEBI:24436 name: guanidines namespace: chebi_ontology def: "Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas." [] subset: 3_STAR is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:24469 name: haloalkane namespace: chebi_ontology def: "A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom." [] subset: 3_STAR synonym: "alkyl halide" RELATED [ChEBI] synonym: "alkyl halides" RELATED [ChEBI] synonym: "haloalkanes" RELATED [ChEBI] is_a: CHEBI:24472 ! halohydrocarbon [Term] id: CHEBI:24471 name: halogen molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "halogen compounds" RELATED [ChEBI] synonym: "halogen molecular entities" RELATED [ChEBI] synonym: "halogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:24473 ! halogen [Term] id: CHEBI:24472 name: halohydrocarbon namespace: chebi_ontology def: "A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom." [] subset: 3_STAR synonym: "halogenated hydrocarbons" RELATED [ChEBI] synonym: "halohydrocarbons" RELATED [ChEBI] is_a: CHEBI:17792 ! organohalogen compound relationship: has_parent_hydride CHEBI:24632 ! hydrocarbon [Term] id: CHEBI:24473 name: halogen namespace: chebi_ontology subset: 3_STAR synonym: "group 17 elements" RELATED [ChEBI] synonym: "group VII elements" RELATED [ChEBI] synonym: "halogen" EXACT IUPAC_NAME [IUPAC] synonym: "Halogene" RELATED [ChEBI] synonym: "halogene" RELATED [ChEBI] synonym: "halogenes" RELATED [ChEBI] synonym: "halogeno" RELATED [ChEBI] synonym: "halogenos" RELATED [ChEBI] synonym: "halogens" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:24532 name: organic heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." [] subset: 3_STAR synonym: "organic heterocycle" RELATED [ChEBI] synonym: "organic heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33832 ! organic cyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:24564 name: hexamethylmelamine namespace: chebi_ontology subset: 3_STAR synonym: "2,4,6-tris(dimethylamino)-1,3,5-triazine" RELATED [ChemIDplus] synonym: "2,4,6-tris(dimethylamino)-s-triazine" RELATED [NIST_Chemistry_WebBook] synonym: "altretamina" RELATED INN [ChemIDplus] synonym: "altretamine" RELATED INN [ChemIDplus] synonym: "altretaminum" RELATED INN [ChemIDplus] synonym: "Hexalen" RELATED BRAND_NAME [ChemIDplus] synonym: "Hexastat" RELATED BRAND_NAME [ChemIDplus] synonym: "HMM" RELATED [ChemIDplus] synonym: "N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:195058 {source="Beilstein"} xref: CAS:645-05-6 {source="ChemIDplus"} xref: CAS:645-05-6 {source="NIST Chemistry WebBook"} xref: Drug_Central:141 {source="DrugCentral"} xref: Gmelin:603940 {source="Gmelin"} xref: LINCS:LSM-3492 xref: Patent:DE1240870 xref: Patent:US3424752 xref: Wikipedia:Altretamine is_a: CHEBI:38175 ! triamino-1,3,5-triazine is_a: FBcv:0000586 ! hexamethylmelamine equivalent_to: FBcv:0000586 ! hexamethylmelamine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H18N6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UUVWYPNAQBNQJQ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "210.27966" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "210.15929" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CN(C)c1nc(nc(n1)N(C)C)N(C)C" xsd:string [Term] id: CHEBI:24565 name: hexamethylphosphoric triamide namespace: chebi_ontology subset: 3_STAR synonym: "HEMPA" RELATED [NIST_Chemistry_WebBook] synonym: "hexamethylorthophosphoric triamide" RELATED [NIST_Chemistry_WebBook] synonym: "Hexamethylphosphoramid" RELATED [ChEBI] synonym: "hexamethylphosphoramide" RELATED [ChEBI] synonym: "hexamethylphosphoric acid triamide" RELATED [ChemIDplus] synonym: "hexamethylphosphoric triamide" EXACT [ChemIDplus] synonym: "Hexamethylphosphorsaeuretriamid" RELATED [ChEBI] synonym: "HMPA" RELATED [ChemIDplus] synonym: "HMPA" RELATED [KEGG_COMPOUND] synonym: "HMPT" RELATED [ChemIDplus] synonym: "HMPTA" RELATED [ChemIDplus] synonym: "N,N,N',N',N'',N''-hexamethylphosphoric triamide" EXACT IUPAC_NAME [IUPAC] synonym: "phosphoric acid hexamethyltriamide" RELATED [NIST_Chemistry_WebBook] synonym: "phosphoric hexamethyltriamide" RELATED [NIST_Chemistry_WebBook] synonym: "phosphoric tris(dimethylamide)" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1099903 {source="Beilstein"} xref: CAS:680-31-9 {source="ChemIDplus"} xref: CAS:680-31-9 {source="NIST Chemistry WebBook"} xref: CAS:680-31-9 {source="KEGG COMPOUND"} xref: Gmelin:3259 {source="Gmelin"} xref: KEGG:C19250 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:17102 ! phosphoramide is_a: FBcv:0000587 ! hexamethylphosphoramide equivalent_to: FBcv:0000587 ! hexamethylphosphoramide relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:67105 ! insect sterilant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H18N3OP" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C6H18N3OP/c1-7(2)11(10,8(3)4)9(5)6/h1-6H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "GNOIPBMMFNIUFM-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "179.20050" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "179.11875" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CN(C)P(=O)(N(C)C)N(C)C" xsd:string [Term] id: CHEBI:24624 name: hycanthone mesylate namespace: chebi_ontology def: "A methanesulfonate salt resulting from the reaction of equimolar amounts of hycanthone and methanesulfonic acid. It was formerly used as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel." [] subset: 3_STAR synonym: "1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-10H-dibenzo[b,e]thiopyran-10-one methanesulfonate" EXACT IUPAC_NAME [IUPAC] synonym: "Etrenol" RELATED BRAND_NAME [ChEBI] synonym: "hycanthone methanesulfonate" RELATED [ChemIDplus] synonym: "hycanthone methanesulphonate" RELATED [ChemIDplus] synonym: "hycanthone monomesylate" RELATED [ChEBI] synonym: "hycanthone monomethanesulfonate" RELATED [ChemIDplus] synonym: "hycanthone monomethanesulphonate" RELATED [ChemIDplus] synonym: "N,N-diethyl-2-{[4-(hydroxymethyl)-10-oxo-10H-dibenzo[b,e]thiopyran-1-yl]amino}ethanaminium methanesulfonate" RELATED [IUPAC] synonym: "N-[2-(diethylamino)ethyl]-4-methoxy-9-oxoxanthene-1-amine monomethanesulfonate" RELATED [ChEBI] xref: CAS:23255-93-8 {source="ChemIDplus"} xref: CAS:23255-93-8 {source="KEGG COMPOUND"} xref: KEGG:C19432 xref: PMID:1206768 {source="Europe PMC"} xref: PMID:1618027 {source="Europe PMC"} xref: PMID:2266978 {source="Europe PMC"} xref: PMID:2499511 {source="Europe PMC"} xref: PMID:2503417 {source="Europe PMC"} xref: PMID:3104567 {source="Europe PMC"} xref: PMID:6408464 {source="Europe PMC"} xref: PMID:6815525 {source="Europe PMC"} xref: PMID:8375330 {source="Europe PMC"} xref: Reaxys:4096157 {source="Reaxys"} is_a: CHEBI:38037 ! methanesulfonate salt is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000532 ! hycanthon methanesulfonate equivalent_to: FBcv:0000532 ! hycanthon methanesulfonate relationship: has_part CHEBI:67141 ! hycanthone(1+) relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:38941 ! schistosomicide drug property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H28N2O5S2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C20H24N2O2S.CH4O3S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20;1-5(2,3)4/h5-10,21,23H,3-4,11-13H2,1-2H3;1H3,(H,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LOEQGPPJCCUXEJ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "452.58700" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "452.14396" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CS(O)(=O)=O.CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12" xsd:string [Term] id: CHEBI:24632 name: hydrocarbon namespace: chebi_ontology def: "A compound consisting of carbon and hydrogen only." [] subset: 3_STAR synonym: "hidrocarburo" RELATED [IUPAC] synonym: "hidrocarburos" RELATED [IUPAC] synonym: "hydrocarbon" EXACT IUPAC_NAME [IUPAC] synonym: "hydrocarbons" EXACT IUPAC_NAME [IUPAC] synonym: "hydrocarbure" RELATED [IUPAC] synonym: "Kohlenwasserstoff" RELATED [ChEBI] synonym: "Kohlenwasserstoffe" RELATED [ChEBI] is_a: CHEBI:33245 ! organic fundamental parent [Term] id: CHEBI:24646 name: hydroquinones namespace: chebi_ontology alt_id: CHEBI:134188 def: "Benzenediols that have the hydroxy substituents in the 1- and 4-positions." [] subset: 3_STAR synonym: "1,4-benzoquinols" RELATED [ChEBI] synonym: "a 1,4-benzoquinol" RELATED [ChEBI] synonym: "a quinol" RELATED [UniProt] synonym: "benzene-1,4-diols" RELATED [ChEBI] is_a: CHEBI:33570 ! benzenediols property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H2O2R4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "106.079" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "106.00548" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC1=C(*)C(*)=C(O)C(*)=C1*" xsd:string [Term] id: CHEBI:24651 name: hydroxides namespace: chebi_ontology def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." [] subset: 3_STAR is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:43176 ! hydroxy group [Term] id: CHEBI:24697 name: hydroxyflavanone namespace: chebi_ontology def: "A member of the class of flavanones that consists of flavanone with one or more hydroxy substituents." [] subset: 3_STAR synonym: "hydroxyflavanone" EXACT [ChEBI] synonym: "hydroxyflavanones" RELATED [ChEBI] is_a: CHEBI:28863 ! flavanones is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CHEBI:24727 name: hydroxynaphthalene namespace: chebi_ontology def: "Any member of the class of naphthalenes that is naphthalene carrying one or more hydroxy groups." [] subset: 3_STAR is_a: CHEBI:25477 ! naphthalenes is_a: CHEBI:33853 ! phenols [Term] id: CHEBI:24833 name: oxoacid namespace: chebi_ontology def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [] subset: 3_STAR synonym: "oxacids" RELATED [ChEBI] synonym: "oxiacids" RELATED [ChEBI] synonym: "oxo acid" RELATED [ChEBI] synonym: "oxoacid" EXACT IUPAC_NAME [IUPAC] synonym: "oxoacids" EXACT IUPAC_NAME [IUPAC] synonym: "oxy-acids" RELATED [ChEBI] synonym: "oxyacids" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24651 ! hydroxides relationship: has_role CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:24834 name: inorganic anion namespace: chebi_ontology subset: 3_STAR synonym: "inorganic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36914 ! inorganic ion [Term] id: CHEBI:24835 name: inorganic molecular entity namespace: chebi_ontology def: "A molecular entity that contains no carbon." [] subset: 3_STAR synonym: "anorganische Verbindungen" RELATED [ChEBI] synonym: "inorganic compounds" RELATED [ChEBI] synonym: "inorganic entity" RELATED [ChEBI] synonym: "inorganic molecular entities" RELATED [ChEBI] synonym: "inorganics" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity is_a: FBcv:0000553 ! inorganic compound equivalent_to: FBcv:0000553 ! inorganic compound [Term] id: CHEBI:24836 name: inorganic oxide namespace: chebi_ontology subset: 3_STAR synonym: "inorganic oxides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25741 ! oxide is_a: FBcv:0000553 ! inorganic compound [Term] id: CHEBI:24839 name: inorganic salt namespace: chebi_ontology subset: 3_STAR synonym: "anorganisches Salz" RELATED [ChEBI] synonym: "inorganic salts" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:24866 ! salt is_a: FBcv:0000553 ! inorganic compound [Term] id: CHEBI:24840 name: inorganic sulfate salt namespace: chebi_ontology subset: 3_STAR synonym: "inorganic sulfate salts" RELATED [ChEBI] synonym: "inorganic sulfates" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:35175 ! sulfate salt is_a: FBcv:0000553 ! inorganic compound [Term] id: CHEBI:24852 name: insecticide namespace: chebi_ontology def: "Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects." [] subset: 3_STAR synonym: "insecticides" RELATED [ChEBI] xref: Wikipedia:Insecticide is_a: CHEBI:25944 ! pesticide [Term] id: CHEBI:24853 name: intercalator namespace: chebi_ontology def: "A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages." [] subset: 3_STAR synonym: "agente intercalante" RELATED [ChEBI] synonym: "intercalating agent" RELATED [ChEBI] synonym: "intercalating agents" RELATED [ChEBI] synonym: "intercalating ligands" RELATED [ChEBI] synonym: "intercalators" RELATED [ChEBI] is_a: CHEBI:25435 ! mutagen [Term] id: CHEBI:24859 name: iodine atom namespace: chebi_ontology def: "Chemical element with atomic number 53." [] subset: 3_STAR synonym: "53I" RELATED [IUPAC] synonym: "I" RELATED [ChEBI] synonym: "Iod" RELATED [ChEBI] synonym: "iode" RELATED [ChEBI] synonym: "iodine" EXACT IUPAC_NAME [IUPAC] synonym: "iodine" RELATED [ChEBI] synonym: "iodium" RELATED [ChEBI] synonym: "J" RELATED [ChEBI] synonym: "Jod" RELATED [ChEBI] synonym: "yodo" RELATED [ChEBI] xref: WebElements:I is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24473 ! halogen is_a: CHEBI:24835 ! inorganic molecular entity is_a: FBcv:0000553 ! inorganic compound is_a: FBcv:0000588 ! iodine equivalent_to: FBcv:0000588 ! iodine relationship: has_role CHEBI:27027 ! micronutrient relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "I" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/I" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ZCYVEMRRCGMTRW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "126.90447" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "126.90447" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[I]" xsd:string [Term] id: CHEBI:24866 name: salt namespace: chebi_ontology def: "A salt is an assembly of cations and anions." [] subset: 3_STAR synonym: "ionic compound" RELATED [ChEBI] synonym: "ionic compounds" RELATED [ChEBI] synonym: "sal" RELATED [ChEBI] synonym: "sales" RELATED [ChEBI] synonym: "salt" EXACT IUPAC_NAME [IUPAC] synonym: "salts" RELATED [ChEBI] synonym: "Salz" RELATED [ChEBI] synonym: "Salze" RELATED [ChEBI] synonym: "sel" RELATED [ChEBI] synonym: "sels" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:22563 ! anion relationship: has_part CHEBI:36916 ! cation [Term] id: CHEBI:24867 name: monoatomic ion namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:33238 ! monoatomic entity [Term] id: CHEBI:24868 name: organic salt namespace: chebi_ontology subset: 3_STAR synonym: "organic salts" RELATED [ChEBI] synonym: "organisches Salz" RELATED [ChEBI] is_a: CHEBI:24866 ! salt [Term] id: CHEBI:24870 name: ion namespace: chebi_ontology def: "A molecular entity having a net electric charge." [] subset: 3_STAR synonym: "Ion" EXACT [ChEBI] synonym: "ion" EXACT IUPAC_NAME [IUPAC] synonym: "ion" EXACT [ChEBI] synonym: "Ionen" RELATED [ChEBI] synonym: "iones" RELATED [ChEBI] synonym: "ions" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:24921 name: isoquinoline alkaloid namespace: chebi_ontology def: "Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine." [] subset: 3_STAR synonym: "isoquinoline alkaloids" RELATED [ChEBI] is_a: CHEBI:22315 ! alkaloid [Term] id: CHEBI:25212 name: metabolite namespace: chebi_ontology alt_id: CHEBI:26619 alt_id: CHEBI:35220 def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." [] subset: 3_STAR synonym: "metabolite" EXACT IUPAC_NAME [IUPAC] synonym: "metabolites" RELATED [ChEBI] synonym: "primary metabolites" RELATED [ChEBI] synonym: "secondary metabolites" RELATED [ChEBI] is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:25213 name: metal cation namespace: chebi_ontology subset: 3_STAR synonym: "a metal cation" RELATED [UniProt] synonym: "metal cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:25223 name: methanesulfonate ester namespace: chebi_ontology def: "An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol." [] subset: 3_STAR synonym: "mesylate ester" RELATED [ChEBI] synonym: "mesylate esters" RELATED [ChEBI] synonym: "methanesulfonic acid esters" RELATED [ChEBI] is_a: CHEBI:48544 ! methanesulfonates is_a: CHEBI:83347 ! organosulfonic ester property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3O3SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "95.099" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.98029" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CS(O*)(=O)=O" xsd:string [Term] id: CHEBI:25224 name: methanesulfonate namespace: chebi_ontology def: "A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid." [] subset: 3_STAR synonym: "methanesulfonate" EXACT IUPAC_NAME [IUPAC] synonym: "methanesulfonate" EXACT [UniProt] synonym: "methylsulfonate" RELATED [UM-BBD] xref: MetaCyc:CPD-3746 xref: UM-BBD_compID:c0347 {source="UM-BBD"} is_a: CHEBI:62081 ! 1,1-diunsubstituted alkanesulfonate relationship: is_conjugate_base_of CHEBI:27376 ! methanesulfonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3O3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "AFVFQIVMOAPDHO-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "95.09872" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.98084" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CS([O-])(=O)=O" xsd:string [Term] id: CHEBI:25234 name: 1-methoxy-N-nitrosodiethylamine namespace: chebi_ontology subset: 3_STAR synonym: "N-ethyl-1-methoxy-N-nitrosoethanamine" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:4368978 {source="ChemIDplus"} xref: CAS:61738-03-2 {source="ChemIDplus"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35803 ! nitrosamine is_a: FBcv:0000590 ! methoxy diethylnitrosamine equivalent_to: FBcv:0000590 ! methoxy diethylnitrosamine relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H12N2O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H12N2O2/c1-4-7(6-8)5(2)9-3/h5H,4H2,1-3H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DCUKVUVLSDGDEZ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "132.16106" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "132.08988" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(N=O)C(C)OC" xsd:string [Term] id: CHEBI:25240 name: methoxyflavanone namespace: chebi_ontology def: "A member of the class of flavanones that consists of flavanone with one or more methoxy substituents." [] subset: 3_STAR synonym: "methoxyflavanones" RELATED [ChEBI] is_a: CHEBI:28863 ! flavanones is_a: CHEBI:35618 ! aromatic ether [Term] id: CHEBI:25255 name: methyl methanesulfonate namespace: chebi_ontology def: "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol." [] subset: 3_STAR synonym: "as-Dimethyl sulfite" RELATED [ChemIDplus] synonym: "CB1540" RELATED [ChEBI] synonym: "Methanesulfonic acid methyl ester" RELATED [ChemIDplus] synonym: "Methyl mesylate" RELATED [ChemIDplus] synonym: "methyl methanesulfonate" EXACT IUPAC_NAME [IUPAC] synonym: "MMS" RELATED [KEGG_COMPOUND] synonym: "MMS" RELATED [ChemIDplus] xref: CAS:66-27-3 {source="ChemIDplus"} xref: CAS:66-27-3 {source="KEGG COMPOUND"} xref: KEGG:C19181 xref: MetaCyc:CPD-7038 xref: PMID:11016630 {source="Europe PMC"} xref: PMID:14761437 {source="Europe PMC"} xref: PMID:16764919 {source="Europe PMC"} xref: PMID:21353429 {source="Europe PMC"} xref: PMID:21860482 {source="Europe PMC"} xref: PMID:22907509 {source="Europe PMC"} xref: PMID:23117069 {source="Europe PMC"} xref: PMID:23384783 {source="Europe PMC"} xref: PMID:23483329 {source="Europe PMC"} xref: Reaxys:1098586 {source="Reaxys"} xref: Wikipedia:Methyl_methanesulfonate is_a: CHEBI:25223 ! methanesulfonate ester is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000533 ! methyl methanesulfonate equivalent_to: FBcv:0000533 ! methyl methanesulfonate relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:50902 ! genotoxin relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:68495 ! apoptosis inducer property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H6O3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MBABOKRGFJTBAE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "110.13200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "110.00377" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COS(C)(=O)=O" xsd:string [Term] id: CHEBI:25348 name: methylxanthine namespace: chebi_ontology subset: 3_STAR synonym: "methylxanthines" RELATED [ChEBI] is_a: CHEBI:26385 ! purine alkaloid relationship: has_functional_parent CHEBI:15318 ! xanthine [Term] id: CHEBI:25357 name: mitomycin namespace: chebi_ontology def: "A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae." [] subset: 3_STAR synonym: "mitomycins" RELATED [ChEBI] xref: PMID:19777135 {source="Europe PMC"} xref: Wikipedia:Mitomycin is_a: CHEBI:23003 ! carbamate ester is_a: CHEBI:25830 ! p-quinones is_a: CHEBI:38303 ! azirinopyrroloindole is_a: FBcv:0000541 ! intercalating agent relationship: has_role CHEBI:24853 ! intercalator relationship: has_role CHEBI:76969 ! bacterial metabolite [Term] id: CHEBI:25367 name: molecule namespace: chebi_ontology def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." [] subset: 3_STAR synonym: "molecula" RELATED [IUPAC] synonym: "molecule" EXACT [IUPAC] synonym: "molecules" RELATED [IUPAC] synonym: "Molekuel" RELATED [ChEBI] synonym: "neutral molecular compounds" RELATED [IUPAC] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:25384 name: monocarboxylic acid namespace: chebi_ontology def: "An oxoacid containing a single carboxy group." [] subset: 3_STAR synonym: "monocarboxylic acids" RELATED [ChEBI] is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35757 ! monocarboxylic acid anion [Term] id: CHEBI:25392 name: naphthols namespace: chebi_ontology def: "Any hydroxynaphthalene derivative that has a single hydroxy substituent." [] subset: 3_STAR is_a: CHEBI:24727 ! hydroxynaphthalene [Term] id: CHEBI:25414 name: monoatomic monocation namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic monocations" RELATED [ChEBI] synonym: "monovalent inorganic cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*+]" xsd:string [Term] id: CHEBI:25434 name: bis(2-chloroethyl) sulfide namespace: chebi_ontology def: "An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention." [] subset: 3_STAR synonym: "1,1'-thiobis(2-chloroethane)" RELATED [NIST_Chemistry_WebBook] synonym: "1-chloro-2-[(2-chloroethyl)sulfanyl]ethane" EXACT IUPAC_NAME [IUPAC] synonym: "1-chloro-2-[(2-chloroethyl)thio]ethane" RELATED [IUPAC] synonym: "bis(2-chloroethyl) sulfide" EXACT [ChemIDplus] synonym: "bis(2-chloroethyl) sulphide" RELATED [NIST_Chemistry_WebBook] synonym: "bis(2-chloroethyl)sulfane" RELATED [IUPAC] synonym: "Iprit" RELATED [KEGG_COMPOUND] synonym: "Lost" RELATED [NIST_Chemistry_WebBook] synonym: "Mustard gas" RELATED [KEGG_COMPOUND] synonym: "mustard gas" RELATED [ChemIDplus] synonym: "Senfgas" RELATED [NIST_Chemistry_WebBook] synonym: "sulfur mustard" RELATED [ChemIDplus] synonym: "Yperite" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1733595 {source="ChemIDplus"} xref: CAS:505-60-2 {source="ChemIDplus"} xref: CAS:505-60-2 {source="KEGG COMPOUND"} xref: CAS:505-60-2 {source="NIST Chemistry WebBook"} xref: Gmelin:324535 {source="Gmelin"} xref: KEGG:C19164 xref: PMID:15908294 {source="Europe PMC"} xref: PMID:19559099 {source="Europe PMC"} xref: PMID:23091586 {source="Europe PMC"} xref: PMID:24467472 {source="Europe PMC"} xref: PMID:24641121 {source="Europe PMC"} xref: PMID:24791566 {source="Europe PMC"} xref: PMID:24801489 {source="Europe PMC"} xref: Wikipedia:Sulfur_mustard is_a: CHEBI:23996 ! ethyl sulfide is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000534 ! bis(2-chloroethyl) sulfide equivalent_to: FBcv:0000534 ! bis(2-chloroethyl) sulfide relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:78592 ! vesicant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H8Cl2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H8Cl2S/c5-1-3-7-4-2-6/h1-4H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QKSKPIVNLNLAAV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "159.07772" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "157.97238" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "ClCCSCCCl" xsd:string [Term] id: CHEBI:25435 name: mutagen namespace: chebi_ontology def: "An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution." [] subset: 3_STAR synonym: "mutagene" RELATED [ChEBI] synonym: "mutagenes" RELATED [ChEBI] synonym: "mutagenic agent" RELATED [ChEBI] synonym: "mutageno" RELATED [ChEBI] synonym: "mutagenos" RELATED [ChEBI] synonym: "mutagens" RELATED [ChEBI] xref: Wikipedia:Mutagen is_a: CHEBI:50902 ! genotoxin [Term] id: CHEBI:25477 name: naphthalenes namespace: chebi_ontology def: "Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings." [] subset: 3_STAR is_a: CHEBI:33836 ! benzenoid aromatic compound is_a: CHEBI:36785 ! carbobicyclic compound [Term] id: CHEBI:25491 name: nematicide namespace: chebi_ontology def: "A substance used to destroy pests of the phylum Nematoda (roundworms)." [] subset: 3_STAR synonym: "nematicides" RELATED [ChEBI] synonym: "nematocide" RELATED [ChEBI] synonym: "nematocides" RELATED [ChEBI] xref: Wikipedia:Nematicide is_a: CHEBI:25944 ! pesticide [Term] id: CHEBI:25512 name: neurotransmitter namespace: chebi_ontology def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." [] subset: 3_STAR synonym: "neurotransmitters" RELATED [ChEBI] xref: Wikipedia:Neurotransmitter is_a: CHEBI:33280 ! molecular messenger [Term] id: CHEBI:25555 name: nitrogen atom namespace: chebi_ontology subset: 3_STAR synonym: "7N" RELATED [IUPAC] synonym: "azote" RELATED [IUPAC] synonym: "N" RELATED [IUPAC] synonym: "nitrogen" EXACT IUPAC_NAME [IUPAC] synonym: "nitrogen" RELATED [ChEBI] synonym: "nitrogeno" RELATED [ChEBI] synonym: "Stickstoff" RELATED [ChEBI] xref: WebElements:N is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "14.007" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string [Term] id: CHEBI:25585 name: nonmetal atom namespace: chebi_ontology subset: 3_STAR synonym: "Nichtmetall" RELATED [ChEBI] synonym: "Nichtmetalle" RELATED [ChEBI] synonym: "no metal" RELATED [ChEBI] synonym: "no metales" RELATED [ChEBI] synonym: "non-metal" RELATED [ChEBI] synonym: "non-metaux" RELATED [ChEBI] synonym: "nonmetal" EXACT IUPAC_NAME [IUPAC] synonym: "nonmetal" RELATED [ChEBI] synonym: "nonmetals" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:25693 name: organic heteromonocyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic heteromonocyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33670 ! heteromonocyclic compound [Term] id: CHEBI:25696 name: organic anion namespace: chebi_ontology def: "Any organic ion with a net negative charge." [] subset: 3_STAR synonym: "organic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:25699 ! organic ion [Term] id: CHEBI:25697 name: organic cation namespace: chebi_ontology def: "Any organic ion with a net positive charge." [] subset: 3_STAR synonym: "organic cations" RELATED [ChEBI] is_a: CHEBI:25699 ! organic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:25698 name: ether namespace: chebi_ontology def: "An organooxygen compound with formula ROR, where R is not hydrogen." [] subset: 3_STAR synonym: "ether" EXACT IUPAC_NAME [IUPAC] synonym: "ethers" EXACT IUPAC_NAME [IUPAC] synonym: "ethers" RELATED [ChEBI] is_a: CHEBI:36963 ! organooxygen compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "OR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]O[*]" xsd:string [Term] id: CHEBI:25699 name: organic ion namespace: chebi_ontology subset: 3_STAR synonym: "organic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:25704 name: organic sulfate namespace: chebi_ontology def: "Compounds of the general formula SO3HOR where R is an organyl group" [] subset: 3_STAR synonym: "organic sulfates" RELATED [ChEBI] is_a: CHEBI:26820 ! sulfates relationship: is_conjugate_acid_of CHEBI:58958 ! organosulfate oxoanion [Term] id: CHEBI:25741 name: oxide namespace: chebi_ontology def: "An oxide is a chemical compound of oxygen with other chemical elements." [] subset: 3_STAR synonym: "oxide" EXACT [ChEBI] synonym: "oxides" RELATED [ChEBI] is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:25805 name: oxygen atom namespace: chebi_ontology subset: 3_STAR synonym: "8O" RELATED [IUPAC] synonym: "O" RELATED [IUPAC] synonym: "oxigeno" RELATED [ChEBI] synonym: "oxygen" EXACT IUPAC_NAME [IUPAC] synonym: "oxygen" RELATED [ChEBI] synonym: "oxygene" RELATED [ChEBI] synonym: "Sauerstoff" RELATED [ChEBI] xref: KEGG:C00007 xref: WebElements:O is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QVGXLLKOCUKJST-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O]" xsd:string [Term] id: CHEBI:25806 name: oxygen molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "oxygen molecular entities" RELATED [ChEBI] synonym: "oxygen molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:25805 ! oxygen atom [Term] id: CHEBI:25810 name: oxopurine namespace: chebi_ontology subset: 3_STAR synonym: "oxopurines" RELATED [ChEBI] is_a: CHEBI:26401 ! purines [Term] id: CHEBI:25813 name: p-N,N-bis(2-chloroethyl)aminophenylvaleric acid namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:33856 ! aromatic amino acid is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000594 ! p-N,N-di(2-chloroethyl)aminophenylvaleric acid equivalent_to: FBcv:0000594 ! p-N,N-di(2-chloroethyl)aminophenylvaleric acid relationship: has_functional_parent CHEBI:17418 ! valeric acid relationship: has_role CHEBI:25435 ! mutagen [Term] id: CHEBI:25814 name: p-N,N-bis(2-chloroethyl)amino-D-phenylalanine namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:16733 ! D-alpha-amino acid is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:84143 ! D-phenylalanine derivative is_a: FBcv:0000595 ! p-N,N-di-(2-chloroethyl)amino-D-phenylalanine equivalent_to: FBcv:0000595 ! p-N,N-di-(2-chloroethyl)amino-D-phenylalanine relationship: has_role CHEBI:25435 ! mutagen [Term] id: CHEBI:25816 name: p-N,N-bis(2-chloroethyl)amino-L-phenylalanine namespace: chebi_ontology subset: 1_STAR is_a: BFO:0000004 ! independent continuant is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:84144 ! L-phenylalanine derivative is_a: FBcv:0000597 ! p-N,N-di-(2-chloroethyl)amino-L-phenylalanine equivalent_to: FBcv:0000597 ! p-N,N-di-(2-chloroethyl)amino-L-phenylalanine relationship: has_role CHEBI:25435 ! mutagen [Term] id: CHEBI:25818 name: 4-(2-aminoethyl)-N,N-bis(2-chloroethyl)aniline namespace: chebi_ontology subset: 3_STAR synonym: "4-(2-aminoethyl)-N,N-bis(2-chloroethyl)aniline" EXACT IUPAC_NAME [IUPAC] synonym: "4-(bis(2-chloroethyl)amino)benzeneethanamine" RELATED [ChemIDplus] synonym: "CB 3034" RELATED [ChemIDplus] synonym: "p-(bis(2-chloroethyl)amino)phenethylamine" RELATED [ChemIDplus] synonym: "p-N,N-di-(2-chloroethyl)aminophenylethylamine" RELATED [ChemIDplus] xref: Beilstein:3292665 {source="ChemIDplus"} xref: CAS:58880-18-5 {source="ChemIDplus"} is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000599 ! p-N,N-di-(2-chloroethyl)aminophenylethylamine equivalent_to: FBcv:0000599 ! p-N,N-di-(2-chloroethyl)aminophenylethylamine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C12H18Cl2N2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C12H18Cl2N2/c13-6-9-16(10-7-14)12-3-1-11(2-4-12)5-8-15/h1-4H,5-10,15H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "PJKCNYLAFQAJDD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "261.19020" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "260.08470" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCc1ccc(cc1)N(CCCl)CCCl" xsd:string [Term] id: CHEBI:25829 name: p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine namespace: chebi_ontology subset: 1_STAR is_a: BFO:0000004 ! independent continuant is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000600 ! p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine equivalent_to: FBcv:0000600 ! p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine relationship: has_role CHEBI:25435 ! mutagen [Term] id: CHEBI:25830 name: p-quinones namespace: chebi_ontology def: "A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring." [] subset: 3_STAR synonym: "p-quinone" RELATED [ChEBI] synonym: "para-quinones" RELATED [ChEBI] is_a: CHEBI:36141 ! quinone [Term] id: CHEBI:25903 name: peptide antibiotic namespace: chebi_ontology def: "A chemically diverse class of peptides that exhibit antimicrobial properties." [] subset: 3_STAR synonym: "peptide antibiotics" RELATED [ChEBI] xref: MetaCyc:Peptide-Antibiotics xref: PMID:33398258 {source="Europe PMC"} is_a: CHEBI:16670 ! peptide relationship: has_role CHEBI:33281 ! antimicrobial agent [Term] id: CHEBI:25944 name: pesticide namespace: chebi_ontology def: "Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests." [] subset: 3_STAR synonym: "pesticide" EXACT IUPAC_NAME [IUPAC] synonym: "pesticides" RELATED [ChEBI] synonym: "Pestizid" RELATED [ChEBI] synonym: "Pestizide" RELATED [ChEBI] xref: Wikipedia:Pesticide is_a: CHEBI:33232 ! application [Term] id: CHEBI:25985 name: phenylalanine derivative namespace: chebi_ontology def: "An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of phenylalanine by a heteroatom. The definition normally excludes peptides containing phenylalanine residues." [] subset: 3_STAR is_a: CHEBI:83821 ! amino acid derivative relationship: has_functional_parent CHEBI:28044 ! phenylalanine [Term] id: CHEBI:26004 name: phenylpropanoid namespace: chebi_ontology def: "Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin." [] subset: 3_STAR synonym: "phenylpropanoids" RELATED [ChEBI] xref: Wikipedia:Phenylpropanoid is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:26078 name: phosphoric acid namespace: chebi_ontology def: "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." [] subset: 3_STAR synonym: "[PO(OH)3]" RELATED [IUPAC] synonym: "acide phosphorique" RELATED [ChEBI] synonym: "acidum phosphoricum" RELATED [ChEBI] synonym: "H3PO4" RELATED [IUPAC] synonym: "Orthophosphoric acid" RELATED [KEGG_COMPOUND] synonym: "orthophosphoric acid" RELATED [NIST_Chemistry_WebBook] synonym: "Phosphate" RELATED [KEGG_COMPOUND] synonym: "Phosphoric acid" EXACT [KEGG_COMPOUND] synonym: "phosphoric acid" EXACT [IUPAC] synonym: "Phosphorsaeure" RELATED [ChEBI] synonym: "Phosphorsaeureloesungen" RELATED [ChEBI] synonym: "tetraoxophosphoric acid" EXACT IUPAC_NAME [IUPAC] synonym: "trihydrogen tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "trihydroxidooxidophosphorus" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:1921286 {source="Beilstein"} xref: CAS:7664-38-2 {source="NIST Chemistry WebBook"} xref: CAS:7664-38-2 {source="KEGG COMPOUND"} xref: CAS:7664-38-2 {source="ChemIDplus"} xref: Drug_Central:4478 {source="DrugCentral"} xref: Gmelin:2000 {source="Gmelin"} xref: HMDB:HMDB0002142 xref: KEGG:C00009 xref: KEGG:D05467 xref: KNApSAcK:C00007408 xref: PMID:11455380 {source="Europe PMC"} xref: PMID:15630224 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17518491 {source="Europe PMC"} xref: PMID:22282755 {source="Europe PMC"} xref: PMID:22333268 {source="Europe PMC"} xref: PMID:22381614 {source="Europe PMC"} xref: PMID:22401268 {source="Europe PMC"} xref: Reaxys:1921286 {source="Reaxys"} xref: Wikipedia:Phosphoric_Acid is_a: CHEBI:59698 ! phosphoric acids relationship: has_role CHEBI:33287 ! fertilizer relationship: has_role CHEBI:46787 ! solvent relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:84735 ! algal metabolite relationship: is_conjugate_acid_of CHEBI:35780 ! phosphate ion relationship: is_conjugate_acid_of CHEBI:39745 ! dihydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "97.99520" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.97690" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP(=O)(O[H])O[H]" xsd:string [Term] id: CHEBI:26082 name: phosphorus molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "phosphorus molecular entities" RELATED [ChEBI] is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_part CHEBI:28659 ! phosphorus atom [Term] id: CHEBI:26167 name: polar amino acid namespace: chebi_ontology alt_id: CHEBI:8283 def: "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." [] subset: 3_STAR synonym: "polar amino acid" EXACT [ChEBI] synonym: "polar amino acids" RELATED [ChEBI] synonym: "polar amino-acid" RELATED [ChEBI] synonym: "polar amino-acids" RELATED [ChEBI] xref: MetaCyc:Polar-amino-acids xref: PMID:12016058 {source="Europe PMC"} is_a: CHEBI:33709 ! amino acid relationship: is_tautomer_of CHEBI:62031 ! polar amino acid zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(C(*)N)=O" xsd:string [Term] id: CHEBI:26191 name: polyol namespace: chebi_ontology def: "A compound that contains two or more hydroxy groups." [] subset: 3_STAR synonym: "polyols" RELATED [ChEBI] is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CHEBI:2634 name: amidine namespace: chebi_ontology def: "Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine." [] subset: 3_STAR synonym: "amidine" EXACT [IUPAC] synonym: "Amidines" RELATED [KEGG_COMPOUND] synonym: "amidines" EXACT IUPAC_NAME [IUPAC] synonym: "amidines" RELATED [ChEBI] is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:26373 name: pteridines namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:27171 ! organic heterobicyclic compound is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:26375 name: pterins namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:26373 ! pteridines [Term] id: CHEBI:26385 name: purine alkaloid namespace: chebi_ontology subset: 3_STAR synonym: "purine alkaloids" RELATED [ChEBI] is_a: CHEBI:22315 ! alkaloid is_a: CHEBI:26401 ! purines [Term] id: CHEBI:26386 name: purine nucleobase namespace: chebi_ontology def: "A nucleobase whose skeleton is derived from purine." [] subset: 3_STAR synonym: "a purine nucleobase" RELATED [UniProt] synonym: "purine bases" RELATED [ChEBI] synonym: "purine nucleobase" EXACT [ChEBI] synonym: "purine nucleobases" RELATED [ChEBI] xref: KEGG:C15587 is_a: CHEBI:18282 ! nucleobase is_a: CHEBI:26401 ! purines property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H3N4R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "119.104" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "119.03577" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(NC(=NC=2NC=NC12)*)=*" xsd:string [Term] id: CHEBI:26401 name: purines namespace: chebi_ontology alt_id: CHEBI:13678 def: "A class of imidazopyrimidines that consists of purine and its substituted derivatives." [] subset: 3_STAR is_a: CHEBI:35875 ! imidazopyrimidine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5N4R7" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "116.080" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "116.01230" xsd:string [Term] id: CHEBI:26432 name: pyrimidine nucleobase namespace: chebi_ontology def: "A nucleobase whose skeleton is derived from pyrimidine." [] subset: 3_STAR synonym: "a pyrimidine nucleobase" RELATED [UniProt] synonym: "pyrimidine bases" RELATED [ChEBI] synonym: "pyrimidine nucleobase" EXACT [ChEBI] synonym: "pyrimidine nucleobases" RELATED [ChEBI] is_a: CHEBI:18282 ! nucleobase is_a: CHEBI:39447 ! pyrimidines property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4HN2R4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "77.064" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "77.01397" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N1C(=C(C(=NC1=*)*)*)*" xsd:string [Term] id: CHEBI:26440 name: pyrimidine nucleoside namespace: chebi_ontology subset: 3_STAR synonym: "N-D-Ribosylpyrimidine" RELATED [KEGG_COMPOUND] synonym: "pyrimidine nucleosides" RELATED [ChEBI] xref: KEGG:C03169 is_a: CHEBI:33838 ! nucleoside is_a: CHEBI:39447 ! pyrimidines [Term] id: CHEBI:26491 name: quinhydrone namespace: chebi_ontology subset: 3_STAR synonym: "Chinhydron" RELATED [ChemIDplus] synonym: "cyclohexa-2,5-diene-1,4-dione--benzene-1,4-diol (1:1)" EXACT IUPAC_NAME [IUPAC] synonym: "green hydroquinone" RELATED [NIST_Chemistry_WebBook] synonym: "p-benzoquinhydrone" RELATED [ChemIDplus] synonym: "p-benzoquinone--hydroquinone compound (1:1)" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:3919222 {source="Beilstein"} xref: CAS:106-34-3 {source="ChemIDplus"} xref: CAS:106-34-3 {source="NIST Chemistry WebBook"} xref: Gmelin:253527 {source="Gmelin"} is_a: CHEBI:35504 ! addition compound is_a: FBcv:0000601 ! quinhydrone equivalent_to: FBcv:0000601 ! quinhydrone relationship: has_part CHEBI:16509 ! 1,4-benzoquinone relationship: has_part CHEBI:17594 ! hydroquinone property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C12H10O4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C6H6O2.C6H4O2/c2*7-5-1-2-6(8)4-3-5/h1-4,7-8H;1-4H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BDJXVNRFAQSMAA-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "218.20540" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "218.05791" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Oc1ccc(O)cc1.O=C1C=CC(=O)C=C1" xsd:string [Term] id: CHEBI:26513 name: quinolines namespace: chebi_ontology def: "A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring." [] subset: 3_STAR is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:26548 name: rhamnosylglucoside namespace: chebi_ontology subset: 3_STAR synonym: "rhamnosylglucoside" EXACT [ChEBI] synonym: "rhamnosylglucosides" RELATED [ChEBI] is_a: CHEBI:24400 ! glycoside [Term] id: CHEBI:26587 name: rutinoside namespace: chebi_ontology subset: 3_STAR synonym: "rutinoside" EXACT [ChEBI] synonym: "rutinosides" RELATED [ChEBI] is_a: CHEBI:26548 ! rhamnosylglucoside [Term] id: CHEBI:26588 name: 1,3,5-triazines namespace: chebi_ontology def: "Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure." [] subset: 3_STAR synonym: "s-triazines" RELATED [ChEBI] is_a: CHEBI:38102 ! triazines [Term] id: CHEBI:26607 name: saturated fatty acid namespace: chebi_ontology def: "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." [] subset: 3_STAR synonym: "saturated fatty acid" EXACT [ChEBI] synonym: "saturated fatty acids" RELATED [ChEBI] synonym: "SFA" RELATED [ChEBI] synonym: "SFAs" RELATED [ChEBI] xref: PMID:16492686 {source="Europe PMC"} xref: PMID:19763019 {source="Europe PMC"} xref: PMID:20237329 {source="Europe PMC"} is_a: CHEBI:35366 ! fatty acid [Term] id: CHEBI:26666 name: short-chain fatty acid namespace: chebi_ontology def: "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." [] subset: 3_STAR synonym: "SCFA" RELATED [ChEBI] synonym: "SCFAs" RELATED [ChEBI] synonym: "short-chain fatty acids" RELATED [ChEBI] xref: PMID:16633129 {source="Europe PMC"} xref: PMID:16870803 {source="Europe PMC"} xref: PMID:18203540 {source="Europe PMC"} xref: PMID:20148677 {source="Europe PMC"} is_a: CHEBI:35366 ! fatty acid relationship: is_conjugate_acid_of CHEBI:58951 ! short-chain fatty acid anion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2OR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.017" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string [Term] id: CHEBI:26708 name: sodium atom namespace: chebi_ontology subset: 3_STAR synonym: "11Na" RELATED [IUPAC] synonym: "Na" RELATED [IUPAC] synonym: "Natrium" RELATED [ChemIDplus] synonym: "natrium" RELATED [IUPAC] synonym: "sodio" RELATED [ChemIDplus] synonym: "sodium" EXACT IUPAC_NAME [IUPAC] synonym: "sodium" RELATED [ChEBI] xref: CAS:7440-23-5 {source="ChemIDplus"} xref: Gmelin:16221 {source="Gmelin"} xref: KEGG:C01330 xref: WebElements:Na is_a: BFO:0000004 ! independent continuant is_a: CHEBI:22314 ! alkali metal atom relationship: has_role CHEBI:33937 ! macronutrient relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KEAYESYHFKHZAL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na]" xsd:string [Term] id: CHEBI:26709 name: sodium hydrogensulfite namespace: chebi_ontology def: "An inorganic sodium salt having hydrogensulfite as the counterion." [] subset: 3_STAR synonym: "NaHSO3" RELATED [IUPAC] synonym: "Natriumbisulfit" RELATED [ChEBI] synonym: "Natriumhydrogensulfit" RELATED [ChEBI] synonym: "primaeres Natriumsulfit" RELATED [ChEBI] synonym: "saures Natriumsulfit" RELATED [ChEBI] synonym: "sodium bisulfite" RELATED [ChemIDplus] synonym: "sodium bisulphite" RELATED [ChemIDplus] synonym: "sodium hydrogen sulfite" RELATED [ChemIDplus] synonym: "sodium hydrogensulfite" EXACT IUPAC_NAME [IUPAC] xref: AGR:IND605265115 {source="Europe PMC"} xref: CAS:7631-90-5 {source="ChemIDplus"} xref: Gmelin:22395 {source="Gmelin"} xref: PMID:27905861 {source="Europe PMC"} xref: PMID:30429859 {source="Europe PMC"} xref: PMID:32714086 {source="Europe PMC"} xref: PMID:32785935 {source="Europe PMC"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:38702 ! inorganic sodium salt is_a: CHEBI:48857 ! sulfite salt is_a: FBcv:0000556 ! sodium bisulphite equivalent_to: FBcv:0000556 ! sodium bisulphite relationship: has_part CHEBI:17137 ! hydrogensulfite relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:50904 ! allergen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HNaO3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DWAQJAXMDSEUJJ-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "104.06191" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "103.95441" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na+].OS([O-])=O" xsd:string [Term] id: CHEBI:26712 name: sodium molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "sodium compounds" RELATED [ChEBI] synonym: "sodium molecular entities" RELATED [ChEBI] is_a: CHEBI:33296 ! alkali metal molecular entity relationship: has_part CHEBI:26708 ! sodium atom [Term] id: CHEBI:26714 name: sodium salt namespace: chebi_ontology def: "Any alkali metal salt having sodium(1+) as the cation." [] subset: 3_STAR synonym: "Natriumsalz" RELATED [ChEBI] synonym: "Natriumsalze" RELATED [ChEBI] synonym: "sodium salts" RELATED [ChEBI] is_a: CHEBI:26712 ! sodium molecular entity is_a: CHEBI:35479 ! alkali metal salt relationship: has_part CHEBI:29101 ! sodium(1+) [Term] id: CHEBI:26800 name: styrylquinoline namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:26513 ! quinolines is_a: FBcv:0000603 ! styryl quinoline equivalent_to: FBcv:0000603 ! styryl quinoline [Term] id: CHEBI:26819 name: sulfuric ester namespace: chebi_ontology def: "An ester of an alcohol and sulfuric acid." [] subset: 3_STAR synonym: "sulfate ester" RELATED [ChEBI] synonym: "sulfuric acid ester" RELATED [ChEBI] synonym: "sulfuric acid esters" RELATED [ChEBI] is_a: CHEBI:35701 ! ester is_a: CHEBI:37826 ! sulfuric acid derivative property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]OS(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:26820 name: sulfates namespace: chebi_ontology def: "Salts and esters of sulfuric acid" [] subset: 3_STAR synonym: "sulfates" EXACT [ChEBI] synonym: "sulfuric acid derivative" RELATED [ChEBI] synonym: "sulphates" RELATED [ChEBI] is_a: CHEBI:37826 ! sulfuric acid derivative [Term] id: CHEBI:26822 name: sulfide namespace: chebi_ontology def: "Any sulfur molecular entity that involves either covalently bonded or anionic sulfur." [] subset: 3_STAR synonym: "sulphides" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity [Term] id: CHEBI:26823 name: sulfites namespace: chebi_ontology def: "Any sulfurous acid derivative that is a salt or an ester of sulfurous acid." [] subset: 3_STAR synonym: "Sulfite" RELATED [ChEBI] synonym: "sulfito" RELATED [ChEBI] synonym: "sulfitos" RELATED [ChEBI] synonym: "sulphites" RELATED [ChEBI] xref: Wikipedia:Sulfite is_a: CHEBI:39087 ! sulfurous acid derivative [Term] id: CHEBI:26833 name: sulfur atom namespace: chebi_ontology subset: 3_STAR synonym: "16S" RELATED [IUPAC] synonym: "azufre" RELATED [ChEBI] synonym: "Elemental sulfur" RELATED [KEGG_COMPOUND] synonym: "S" RELATED [KEGG_COMPOUND] synonym: "S" RELATED [IUPAC] synonym: "Schwefel" RELATED [ChEBI] synonym: "soufre" RELATED [ChEBI] synonym: "sulfur" EXACT IUPAC_NAME [IUPAC] synonym: "sulfur" RELATED [ChEBI] synonym: "sulfur" RELATED [UniProt] synonym: "sulphur" RELATED [ChEBI] synonym: "theion" RELATED [IUPAC] xref: CAS:7704-34-9 {source="ChemIDplus"} xref: CAS:7704-34-9 {source="NIST Chemistry WebBook"} xref: KEGG:C00087 xref: KEGG:D06527 xref: PPDB:605 xref: WebElements:S is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NINIDFKCEFEMDL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "32.06600" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.97207" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[S]" xsd:string [Term] id: CHEBI:26834 name: sulfur-containing amino acid namespace: chebi_ontology subset: 3_STAR synonym: "sulfur-containing amino acids" RELATED [ChEBI] is_a: CHEBI:33576 ! sulfur-containing carboxylic acid is_a: CHEBI:33709 ! amino acid relationship: is_conjugate_acid_of CHEBI:63470 ! sulfur-containing amino-acid anion [Term] id: CHEBI:26835 name: sulfur molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "sulfur molecular entities" RELATED [ChEBI] synonym: "sulfur molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:26833 ! sulfur atom [Term] id: CHEBI:26836 name: sulfuric acid namespace: chebi_ontology def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." [] subset: 3_STAR synonym: "[S(OH)2O2]" RELATED [MolBase] synonym: "[SO2(OH)2]" RELATED [IUPAC] synonym: "Acide sulfurique" RELATED [ChemIDplus] synonym: "Acido sulfurico" RELATED [ChemIDplus] synonym: "Acidum sulfuricum" RELATED [ChemIDplus] synonym: "dihydrogen tetraoxosulfate" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidodioxidosulfur" EXACT IUPAC_NAME [IUPAC] synonym: "H2SO4" RELATED [IUPAC] synonym: "hydrogen tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "Schwefelsaeureloesungen" RELATED [ChemIDplus] synonym: "Sulfuric acid" EXACT [KEGG_COMPOUND] synonym: "sulfuric acid" EXACT IUPAC_NAME [IUPAC] synonym: "sulfuric acid" EXACT [ChEBI] synonym: "sulphuric acid" RELATED [MolBase] synonym: "tetraoxosulfuric acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:7664-93-9 {source="ChemIDplus"} xref: CAS:7664-93-9 {source="KEGG COMPOUND"} xref: CAS:7664-93-9 {source="NIST Chemistry WebBook"} xref: Gmelin:2122 {source="Gmelin"} xref: KEGG:C00059 xref: KEGG:D05963 xref: KNApSAcK:C00007530 xref: MolBase:4 xref: PMID:13568755 {source="Europe PMC"} xref: PMID:16122922 {source="Europe PMC"} xref: PMID:19397353 {source="Europe PMC"} xref: PMID:22047659 {source="Europe PMC"} xref: PMID:22136045 {source="Europe PMC"} xref: PMID:22204399 {source="Europe PMC"} xref: PMID:22267186 {source="Europe PMC"} xref: PMID:22296037 {source="Europe PMC"} xref: PMID:22364556 {source="Europe PMC"} xref: PMID:22435616 {source="Europe PMC"} xref: PPDB:606 xref: Reaxys:2037554 {source="Reaxys"} xref: Wikipedia:Sulfuric_acid is_a: CHEBI:33402 ! sulfur oxoacid relationship: has_role CHEBI:35223 ! catalyst relationship: is_conjugate_acid_of CHEBI:45696 ! hydrogensulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "98.07948" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.96738" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS(=O)(=O)O[H]" xsd:string [Term] id: CHEBI:26912 name: oxolanes namespace: chebi_ontology def: "Any oxacycle having an oxolane (tetrahydrofuran) skeleton." [] subset: 3_STAR is_a: CHEBI:25693 ! organic heteromonocyclic compound is_a: CHEBI:38104 ! oxacycle [Term] id: CHEBI:26979 name: organic heterotricyclic compound namespace: chebi_ontology def: "An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms." [] subset: 3_STAR synonym: "heterotricyclic compounds" RELATED [ChEBI] synonym: "organic heterotricyclic compounds" RELATED [ChEBI] is_a: CHEBI:36688 ! heterotricyclic compound is_a: CHEBI:38166 ! organic heteropolycyclic compound is_a: CHEBI:51959 ! organic tricyclic compound [Term] id: CHEBI:27024 name: toluenes namespace: chebi_ontology def: "Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group." [] subset: 3_STAR is_a: CHEBI:22712 ! benzenes [Term] id: CHEBI:27027 name: micronutrient namespace: chebi_ontology def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." [] subset: 3_STAR synonym: "micronutrients" RELATED [ChEBI] synonym: "trace elements" RELATED [ChEBI] xref: Wikipedia:Micronutrient is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:27081 name: transition element atom namespace: chebi_ontology def: "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." [] subset: 3_STAR synonym: "metal de transicion" RELATED [ChEBI] synonym: "metal de transition" RELATED [ChEBI] synonym: "metales de transicion" RELATED [ChEBI] synonym: "metaux de transition" RELATED [ChEBI] synonym: "transition element" EXACT IUPAC_NAME [IUPAC] synonym: "transition element" RELATED [ChEBI] synonym: "transition elements" RELATED [ChEBI] synonym: "transition metal" RELATED [ChEBI] synonym: "transition metals" RELATED [ChEBI] synonym: "Uebergangselement" RELATED [ChEBI] synonym: "Uebergangsmetalle" RELATED [ChEBI] is_a: CHEBI:33521 ! metal atom [Term] id: CHEBI:27090 name: triaziquone namespace: chebi_ontology def: "A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which three of the ring hydrogens are replaced by aziridin-1-yl groups." [] subset: 3_STAR synonym: "1,1',1''-(3,6-Dioxo-1,4-cyclohexadiene-1,2,4-triyl)trisaziridine" RELATED [ChemIDplus] synonym: "2,3,5-Ethylenimine-1,4-benzoquinone" RELATED [NIST_Chemistry_WebBook] synonym: "2,3,5-Tri(1-aziridinyl)-p-benzoquinone" RELATED [NIST_Chemistry_WebBook] synonym: "2,3,5-Tri-(1-aziridinyl)-p-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Triethyleneimino-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Tris(1-aziridino)-p-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Tris(1-aziridinyl)-2,5-cyclohexadiene-1,4-dione" RELATED [NIST_Chemistry_WebBook] synonym: "2,3,5-Tris(1-aziridinyl)-p-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-tris(aziridin-1-yl)-1,4-benzoquinone" EXACT IUPAC_NAME [IUPAC] synonym: "2,3,5-Tris(aziridino)-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Tris(ethyleneimino)-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Tris(ethylenimino)-1,4-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Tris(ethylenimino)-p-benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Tris(ethylenimino)benzoquinone" RELATED [ChemIDplus] synonym: "2,3,5-Trisethyleneiminobenzoquinone" RELATED [ChemIDplus] synonym: "Triazichon" RELATED [ChemIDplus] synonym: "triazicuona" RELATED INN [ChemIDplus] synonym: "triaziquone" RELATED INN [WHO_MedNet] synonym: "triaziquone" RELATED INN [KEGG_DRUG] synonym: "Triaziquonum" RELATED INN [ChemIDplus] synonym: "Triethyleneaminobenzoquinone" RELATED [ChemIDplus] synonym: "Tris(1-aziridinyl)-p-benzoquinone" RELATED [ChemIDplus] synonym: "Tris(aziridinyl)-p-benzoquinone" RELATED [NIST_Chemistry_WebBook] synonym: "Tris(aziridinyl)-para-benzoquinone" RELATED [KEGG_COMPOUND] synonym: "Tris(ethyleneimino)benzoquinone" RELATED [ChemIDplus] xref: CAS:68-76-8 {source="ChemIDplus"} xref: CAS:68-76-8 {source="NIST Chemistry WebBook"} xref: CAS:68-76-8 {source="KEGG COMPOUND"} xref: Drug_Central:4372 {source="DrugCentral"} xref: KEGG:C19542 xref: KEGG:D07254 xref: PMID:146335 {source="Europe PMC"} xref: PMID:20371239 {source="Europe PMC"} xref: PMID:362189 {source="Europe PMC"} xref: PMID:3672382 {source="Europe PMC"} xref: PMID:582920 {source="Europe PMC"} xref: PMID:624547 {source="Europe PMC"} xref: PMID:74416 {source="Europe PMC"} xref: Reaxys:238057 {source="Reaxys"} xref: Wikipedia:Triaziquone is_a: CHEBI:132124 ! 1,4-benzoquinones is_a: CHEBI:22681 ! aziridines is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000604 ! triaziquone equivalent_to: FBcv:0000604 ! triaziquone relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:35610 ! antineoplastic agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C12H13N3O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C12H13N3O2/c16-9-7-8(13-1-2-13)12(17)11(15-5-6-15)10(9)14-3-4-14/h7H,1-6H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "PXSOHRWMIRDKMP-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "231.25050" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "231.10078" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1" xsd:string [Term] id: CHEBI:27134 name: trimethylxanthine namespace: chebi_ontology subset: 3_STAR synonym: "trimethylxanthines" RELATED [ChEBI] is_a: CHEBI:25348 ! methylxanthine [Term] id: CHEBI:27171 name: organic heterobicyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "heterobicyclic compounds" RELATED [ChEBI] synonym: "organic heterobicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33672 ! heterobicyclic compound is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:27207 name: univalent carboacyl group namespace: chebi_ontology def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "univalent acyl group" RELATED [ChEBI] synonym: "univalent carboacyl groups" RELATED [ChEBI] synonym: "univalent carboxylic acyl groups" RELATED [ChEBI] is_a: CHEBI:37838 ! carboacyl group [Term] id: CHEBI:27242 name: uridines namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:39446 ! pyrimidine ribonucleosides relationship: has_functional_parent CHEBI:17568 ! uracil [Term] id: CHEBI:27292 name: vinyl carbamate namespace: chebi_ontology subset: 3_STAR synonym: "carbamic acid, vinyl ester" RELATED [ChemIDplus] synonym: "ethenyl carbamate" RELATED [ChemIDplus] synonym: "vinyl carbamate" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:1921122 {source="ChemIDplus"} xref: CAS:15805-73-9 {source="ChemIDplus"} is_a: CHEBI:13941 ! carbamate is_a: CHEBI:23003 ! carbamate ester is_a: FBcv:0000538 ! carbamate is_a: FBcv:0000540 ! vinyl carbamate equivalent_to: FBcv:0000540 ! vinyl carbamate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H5NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H5NO2/c1-2-6-3(4)5/h2H,1H2,(H2,4,5)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LVLANIHJQRZTPY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "87.07734" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.03203" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(=O)OC=C" xsd:string [Term] id: CHEBI:27311 name: volatile oil component namespace: chebi_ontology def: "Any plant metabolite that is found naturally as a component of a volatile oil." [] subset: 3_STAR synonym: "essential oil component" RELATED [ChEBI] synonym: "essential oil components" RELATED [ChEBI] synonym: "ethereal oil component" RELATED [ChEBI] synonym: "ethereal oil components" RELATED [ChEBI] synonym: "volatile oil components" RELATED [ChEBI] xref: Wikipedia:Essential_oil is_a: CHEBI:76924 ! plant metabolite [Term] id: CHEBI:27314 name: water-soluble vitamin (role) namespace: chebi_ontology def: "Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine." [] subset: 3_STAR synonym: "wasserloesliche Vitamine" RELATED [ChEBI] synonym: "water-soluble vitamin" RELATED [ChEBI] synonym: "water-soluble vitamins" RELATED [ChEBI] is_a: CHEBI:33229 ! vitamin (role) [Term] id: CHEBI:27369 name: zwitterion namespace: chebi_ontology def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." [] subset: 3_STAR synonym: "compose zwitterionique" RELATED [IUPAC] synonym: "compuestos zwitterionicos" RELATED [IUPAC] synonym: "zwitterion" EXACT IUPAC_NAME [IUPAC] synonym: "zwitteriones" RELATED [IUPAC] synonym: "zwitterionic compounds" RELATED [IUPAC] synonym: "zwitterions" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51151 ! dipolar compound [Term] id: CHEBI:27376 name: methanesulfonic acid namespace: chebi_ontology alt_id: CHEBI:6813 def: "An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl." [] subset: 3_STAR synonym: "Methanesulfonic acid" EXACT [KEGG_COMPOUND] synonym: "methanesulfonic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Methansulfonsaeure" RELATED [ChEBI] synonym: "methylsulfonic acid" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1446024 {source="Beilstein"} xref: CAS:75-75-2 {source="KEGG COMPOUND"} xref: CAS:75-75-2 {source="ChemIDplus"} xref: CAS:75-75-2 {source="NIST Chemistry WebBook"} xref: Gmelin:1681 {source="Gmelin"} xref: KEGG:C11145 xref: MetaCyc:CPD-3746 xref: PMID:24304088 {source="Europe PMC"} xref: PMID:24593036 {source="Europe PMC"} xref: Reaxys:1446024 {source="Reaxys"} xref: Wikipedia:Methanesulfonic_acid is_a: BFO:0000004 ! independent continuant is_a: CHEBI:47901 ! alkanesulfonic acid is_a: CHEBI:64708 ! one-carbon compound relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_acid_of CHEBI:25224 ! methanesulfonate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH4O3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "AFVFQIVMOAPDHO-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.10666" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.98812" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CS(O)(=O)=O" xsd:string [Term] id: CHEBI:27470 name: folic acid namespace: chebi_ontology alt_id: CHEBI:24075 alt_id: CHEBI:42610 alt_id: CHEBI:5140 alt_id: CHEBI:569217 def: "An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation." [] subset: 3_STAR synonym: "(2S)-2-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzamido)pentanedioic acid" RELATED [IUPAC] synonym: "Acfol" RELATED BRAND_NAME [ChemIDplus] synonym: "acide folique" RELATED INN [WHO_MedNet] synonym: "acido folico" RELATED INN [WHO_MedNet] synonym: "acidum folicum" RELATED INN [WHO_MedNet] synonym: "Folate" RELATED [KEGG_COMPOUND] synonym: "folic acid" RELATED INN [WHO_MedNet] synonym: "Folicet" RELATED BRAND_NAME [KEGG_DRUG] synonym: "Folsaeure" RELATED [ChEBI] synonym: "N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid" RELATED [PDBeChem] synonym: "N-pteroyl-L-glutamic acid" RELATED [ChEBI] synonym: "PGA" RELATED [NIST_Chemistry_WebBook] synonym: "PteGlu" RELATED [NIST_Chemistry_WebBook] synonym: "pteroyl-L-glutamic acid" RELATED [ChemIDplus] synonym: "pteroyl-L-monoglutamic acid" RELATED [ChemIDplus] synonym: "pteroylglutamic acid" RELATED [KEGG_COMPOUND] synonym: "pteroylmonoglutamic acid" RELATED [ChemIDplus] synonym: "vitamin B11" RELATED [ChemIDplus] synonym: "vitamin B9" RELATED [ChemIDplus] synonym: "vitamin Bc" RELATED [ChemIDplus] synonym: "vitamin Be" RELATED [ChemIDplus] synonym: "vitamin M" RELATED [ChemIDplus] xref: AGR:IND606960789 {source="Europe PMC"} xref: Beilstein:100781 {source="Beilstein"} xref: CAS:59-30-3 {source="KEGG COMPOUND"} xref: CAS:59-30-3 {source="NIST Chemistry WebBook"} xref: CAS:59-30-3 {source="ChemIDplus"} xref: Chemspider:5815 xref: Drug_Central:1231 {source="DrugCentral"} xref: DrugBank:DB00158 xref: FooDB:FDB014504 xref: HMDB:HMDB0000121 xref: KEGG:C00504 xref: KEGG:D00070 xref: KNApSAcK:C00001539 xref: LINCS:LSM-5355 xref: MetaCyc:CPD-12826 xref: PDBeChem:FOL xref: PMID:10138938 {source="Europe PMC"} xref: PMID:10897644 {source="Europe PMC"} xref: PMID:10958818 {source="Europe PMC"} xref: PMID:11261364 {source="Europe PMC"} xref: PMID:11451208 {source="Europe PMC"} xref: PMID:11959400 {source="Europe PMC"} xref: PMID:14387833 {source="Europe PMC"} xref: PMID:15321809 {source="Europe PMC"} xref: PMID:15523939 {source="Europe PMC"} xref: PMID:15754725 {source="Europe PMC"} xref: PMID:15797531 {source="Europe PMC"} xref: PMID:15797685 {source="Europe PMC"} xref: PMID:15831910 {source="Europe PMC"} xref: PMID:15990733 {source="Europe PMC"} xref: PMID:16093404 {source="Europe PMC"} xref: PMID:16277678 {source="Europe PMC"} xref: PMID:16380297 {source="Europe PMC"} xref: PMID:16871332 {source="Europe PMC"} xref: PMID:17784727 {source="Europe PMC"} xref: PMID:18788725 {source="ChEMBL"} xref: PMID:19121630 {source="Europe PMC"} xref: PMID:19335717 {source="Europe PMC"} xref: PMID:19355913 {source="Europe PMC"} xref: PMID:24650098 {source="Europe PMC"} xref: PMID:33624660 {source="Europe PMC"} xref: PMID:33965562 {source="Europe PMC"} xref: PMID:33968971 {source="Europe PMC"} xref: PMID:34207319 {source="Europe PMC"} xref: PMID:34219855 {source="Europe PMC"} xref: PMID:7738698 {source="Europe PMC"} xref: PMID:8235383 {source="Europe PMC"} xref: PMID:9040515 {source="Europe PMC"} xref: PMID:9420019 {source="Europe PMC"} xref: PMID:9565830 {source="Europe PMC"} xref: PMID:9683174 {source="Europe PMC"} xref: PMID:9781393 {source="Europe PMC"} xref: PMID:9808640 {source="Europe PMC"} xref: PMID:9808641 {source="Europe PMC"} xref: Reaxys:100781 {source="Reaxys"} xref: Wikipedia:Folic_Acid is_a: CHEBI:37445 ! folic acids is_a: CHEBI:51569 ! N-acyl-amino acid relationship: has_functional_parent CHEBI:38794 ! pteroic acid relationship: has_role CHEBI:33284 ! nutrient relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:62501 ! folate(2-) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H19N7O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OVBPIULPVIDEAO-LBPRGKRZSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "441.39750" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "441.13968" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)nc2c(=O)[nH]1" xsd:string [Term] id: CHEBI:27504 name: mitomycin C namespace: chebi_ontology alt_id: CHEBI:25356 alt_id: CHEBI:6953 subset: 3_STAR synonym: "7-Amino-9alpha-methoxymitosane" RELATED [ChemIDplus] synonym: "[(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate" EXACT IUPAC_NAME [IUPAC] synonym: "Ametycine" RELATED [ChemIDplus] synonym: "Mitocin-C" RELATED [ChemIDplus] synonym: "Mitomycin" RELATED [KEGG_COMPOUND] synonym: "Mitomycin C" EXACT [KEGG_COMPOUND] synonym: "MMC" RELATED [ChemIDplus] synonym: "Mutamycin" RELATED [ChemIDplus] xref: Beilstein:3570056 {source="Beilstein"} xref: CAS:50-07-7 {source="ChemIDplus"} xref: CAS:50-07-7 {source="KEGG COMPOUND"} xref: Drug_Central:1819 {source="DrugCentral"} xref: DrugBank:DB00305 xref: KEGG:C06681 xref: KEGG:D00208 xref: KNApSAcK:C00018668 xref: LINCS:LSM-6310 xref: Wikipedia:Mitomycin is_a: CHEBI:25357 ! mitomycin is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000542 ! mitomycin C equivalent_to: FBcv:0000542 ! mitomycin C relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:35610 ! antineoplastic agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C15H18N4O5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NWIBSHFKIJFRCO-WUDYKRTCSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "334.32720" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "334.12772" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@]12CN3C4=C([C@@H](COC(N)=O)[C@@]3(OC)[C@@]1([H])N2)C(=O)C(N)=C(C)C4=O" xsd:string [Term] id: CHEBI:27560 name: boron atom namespace: chebi_ontology alt_id: CHEBI:22915 alt_id: CHEBI:3152 subset: 3_STAR synonym: "5B" RELATED [IUPAC] synonym: "B" RELATED [KEGG_COMPOUND] synonym: "Bor" RELATED [ChEBI] synonym: "boracium" RELATED [ChEBI] synonym: "bore" RELATED [ChEBI] synonym: "boro" RELATED [ChEBI] synonym: "Boron" RELATED [KEGG_COMPOUND] synonym: "boron" EXACT IUPAC_NAME [IUPAC] synonym: "boron" RELATED [ChEBI] xref: CAS:7440-42-8 {source="ChemIDplus"} xref: CAS:7440-42-8 {source="KEGG COMPOUND"} xref: KEGG:C06266 xref: WebElements:B is_a: BFO:0000004 ! independent continuant is_a: CHEBI:137980 ! metalloid atom is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33317 ! boron group element atom relationship: has_role CHEBI:27027 ! micronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "B" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/B" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ZOXJGFHDIHLPTG-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "10.81100" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "11.00930" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[B]" xsd:string [Term] id: CHEBI:27561 name: oxirane namespace: chebi_ontology alt_id: CHEBI:24001 alt_id: CHEBI:4900 def: "A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom." [] subset: 3_STAR synonym: "1,2-Epoxyaethan" RELATED [ChemIDplus] synonym: "1,2-epoxyethane" RELATED [NIST_Chemistry_WebBook] synonym: "Aethylenoxid" RELATED [ChemIDplus] synonym: "Amprolene" RELATED [ChemIDplus] synonym: "Anprolene" RELATED [NIST_Chemistry_WebBook] synonym: "Anproline" RELATED [ChemIDplus] synonym: "Dihydrooxirene" RELATED [ChemIDplus] synonym: "Dimethylene oxide" RELATED [ChemIDplus] synonym: "epoxyethane" RELATED [NIST_Chemistry_WebBook] synonym: "ethene oxide" RELATED [NIST_Chemistry_WebBook] synonym: "Ethylene oxide" RELATED [KEGG_COMPOUND] synonym: "ETO" RELATED [ChemIDplus] synonym: "Oxacyclopropane" RELATED [ChemIDplus] synonym: "Oxane" RELATED [ChemIDplus] synonym: "Oxidoethane" RELATED [ChemIDplus] synonym: "oxirane" EXACT IUPAC_NAME [IUPAC] synonym: "oxyde d'ethylene" RELATED [ChemIDplus] synonym: "Oxyfume" RELATED [ChEBI] xref: Beilstein:102378 {source="Beilstein"} xref: CAS:75-21-8 {source="NIST Chemistry WebBook"} xref: CAS:75-21-8 {source="KEGG COMPOUND"} xref: CAS:75-21-8 {source="ChemIDplus"} xref: Gmelin:676 {source="Gmelin"} xref: HMDB:HMDB0031305 xref: KEGG:C06548 xref: KEGG:D03474 xref: PMID:11437638 {source="Europe PMC"} xref: PMID:24313866 {source="Europe PMC"} xref: PMID:24882394 {source="Europe PMC"} xref: PMID:25005741 {source="Europe PMC"} xref: PMID:3932500 {source="Europe PMC"} xref: Reaxys:102378 {source="Reaxys"} xref: UM-BBD_compID:c0527 {source="UM-BBD"} xref: Wikipedia:Oxirane is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent is_a: CHEBI:38104 ! oxacycle is_a: FBcv:0000582 ! ethylene oxide equivalent_to: FBcv:0000582 ! ethylene oxide relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:50904 ! allergen relationship: has_role CHEBI:75771 ! mouse metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O/c1-2-3-1/h1-2H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IAYPIBMASNFSPL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.05256" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.02621" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1CO1" xsd:string [Term] id: CHEBI:27594 name: carbon atom namespace: chebi_ontology alt_id: CHEBI:23009 alt_id: CHEBI:3399 subset: 3_STAR synonym: "6C" RELATED [IUPAC] synonym: "C" RELATED [KEGG_COMPOUND] synonym: "C" RELATED [IUPAC] synonym: "Carbon" RELATED [KEGG_COMPOUND] synonym: "carbon" EXACT IUPAC_NAME [IUPAC] synonym: "carbon" RELATED [ChEBI] synonym: "carbone" RELATED [ChEBI] synonym: "carbonium" RELATED [ChEBI] synonym: "carbono" RELATED [ChEBI] synonym: "Kohlenstoff" RELATED [ChEBI] xref: CAS:7440-44-0 {source="ChemIDplus"} xref: CAS:7440-44-0 {source="KEGG COMPOUND"} xref: KEGG:C06265 xref: WebElements:C is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33306 ! carbon group element atom relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OKTJSMMVPCPJKN-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "12.01070" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "12.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C]" xsd:string [Term] id: CHEBI:27666 name: actinomycin D namespace: chebi_ontology alt_id: CHEBI:22218 alt_id: CHEBI:2446 subset: 3_STAR synonym: "2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide" EXACT IUPAC_NAME [IUPAC] synonym: "2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide" RELATED [ChemIDplus] synonym: "ActD" RELATED [ChEBI] synonym: "actinomycin C1" RELATED [ChEBI] synonym: "Actinomycin D" EXACT [KEGG_COMPOUND] synonym: "actinomycin IV" RELATED [ChemIDplus] synonym: "Dactinomycin" RELATED [KEGG_COMPOUND] xref: Beilstein:4173766 {source="Beilstein"} xref: CAS:50-76-0 {source="ChemIDplus"} xref: CAS:50-76-0 {source="KEGG COMPOUND"} xref: Drug_Central:774 {source="DrugCentral"} xref: DrugBank:DB00970 xref: KEGG:C06770 xref: KEGG:D00214 xref: LINCS:LSM-5783 xref: Wikipedia:Dactinomycin is_a: CHEBI:15369 ! actinomycin is_a: FBcv:0000573 ! actinomycin D equivalent_to: FBcv:0000573 ! actinomycin D relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C62H86N12O16" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RJURFGZVJUQBHK-IIXSONLDSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1255.41700" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1254.62847" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C" xsd:string [Term] id: CHEBI:27732 name: caffeine namespace: chebi_ontology alt_id: CHEBI:22982 alt_id: CHEBI:3295 alt_id: CHEBI:41472 def: "A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee." [] subset: 3_STAR synonym: "1,3,7-trimethyl-2,6-dioxopurine" RELATED [ChemIDplus] synonym: "1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione" EXACT IUPAC_NAME [IUPAC] synonym: "1,3,7-trimethylpurine-2,6-dione" RELATED [IUPHAR] synonym: "1,3,7-Trimethylxanthine" RELATED [KEGG_COMPOUND] synonym: "1,3,7-trimethylxanthine" RELATED [NIST_Chemistry_WebBook] synonym: "1-methyltheobromine" RELATED [ChemIDplus] synonym: "3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion" RELATED [NIST_Chemistry_WebBook] synonym: "7-methyltheophylline" RELATED [NIST_Chemistry_WebBook] synonym: "anhydrous caffeine" RELATED [KEGG_DRUG] synonym: "cafeina" RELATED [ChemIDplus] synonym: "cafeine" RELATED [ChEBI] synonym: "CAFFEINE" EXACT [PDBeChem] synonym: "Caffeine" EXACT [KEGG_COMPOUND] synonym: "caffeine" EXACT [UniProt] synonym: "Coffein" RELATED [ChemIDplus] synonym: "guaranine" RELATED [IUPHAR] synonym: "Koffein" RELATED [ChemIDplus] synonym: "mateina" RELATED [ChemIDplus] synonym: "methyltheobromine" RELATED [IUPHAR] synonym: "teina" RELATED [ChEBI] synonym: "Thein" RELATED [ChemIDplus] synonym: "theine" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:17705 {source="Beilstein"} xref: CAS:58-08-2 {source="NIST Chemistry WebBook"} xref: CAS:58-08-2 {source="ChemIDplus"} xref: CAS:58-08-2 {source="KEGG COMPOUND"} xref: Drug_Central:463 {source="DrugCentral"} xref: DrugBank:DB00201 xref: Gmelin:103040 {source="Gmelin"} xref: HMDB:HMDB0001847 xref: KEGG:C07481 xref: KEGG:D00528 xref: KNApSAcK:C00001492 xref: LINCS:LSM-2026 xref: MetaCyc:1-3-7-TRIMETHYLXANTHINE xref: PDBeChem:CFF xref: PMID:10510174 {source="Europe PMC"} xref: PMID:10796597 {source="Europe PMC"} xref: PMID:10803761 {source="Europe PMC"} xref: PMID:10822912 {source="Europe PMC"} xref: PMID:10884512 {source="Europe PMC"} xref: PMID:10924888 {source="Europe PMC"} xref: PMID:10983026 {source="Europe PMC"} xref: PMID:11014293 {source="Europe PMC"} xref: PMID:11022879 {source="Europe PMC"} xref: PMID:11209966 {source="Europe PMC"} xref: PMID:11312039 {source="Europe PMC"} xref: PMID:11410911 {source="Europe PMC"} xref: PMID:11431501 {source="Europe PMC"} xref: PMID:11815511 {source="Europe PMC"} xref: PMID:11949272 {source="Europe PMC"} xref: PMID:12397877 {source="Europe PMC"} xref: PMID:12457274 {source="Europe PMC"} xref: PMID:12574990 {source="Europe PMC"} xref: PMID:12915014 {source="Europe PMC"} xref: PMID:12943586 {source="Europe PMC"} xref: PMID:14521986 {source="Europe PMC"} xref: PMID:14607010 {source="Europe PMC"} xref: PMID:15257305 {source="Europe PMC"} xref: PMID:15280431 {source="Europe PMC"} xref: PMID:15681408 {source="Europe PMC"} xref: PMID:15718055 {source="Europe PMC"} xref: PMID:15840517 {source="Europe PMC"} xref: PMID:16143823 {source="Europe PMC"} xref: PMID:16391865 {source="Europe PMC"} xref: PMID:16528931 {source="Europe PMC"} xref: PMID:16644114 {source="Europe PMC"} xref: PMID:16709440 {source="Europe PMC"} xref: PMID:16805851 {source="Europe PMC"} xref: PMID:16856769 {source="Europe PMC"} xref: PMID:17132260 {source="Europe PMC"} xref: PMID:17387608 {source="Europe PMC"} xref: PMID:17508167 {source="Europe PMC"} xref: PMID:17724925 {source="Europe PMC"} xref: PMID:17932622 {source="Europe PMC"} xref: PMID:17957400 {source="Europe PMC"} xref: PMID:18068204 {source="Europe PMC"} xref: PMID:18258404 {source="Europe PMC"} xref: PMID:18421070 {source="Europe PMC"} xref: PMID:18513215 {source="Europe PMC"} xref: PMID:18625110 {source="Europe PMC"} xref: PMID:18647558 {source="Europe PMC"} xref: PMID:19007524 {source="Europe PMC"} xref: PMID:19047957 {source="Europe PMC"} xref: PMID:19084078 {source="Europe PMC"} xref: PMID:19088793 {source="Europe PMC"} xref: PMID:19418355 {source="Europe PMC"} xref: PMID:19879252 {source="Europe PMC"} xref: PMID:20164568 {source="Europe PMC"} xref: PMID:20470411 {source="Europe PMC"} xref: PMID:22114686 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:23551936 {source="Europe PMC"} xref: PMID:24039592 {source="Europe PMC"} xref: PMID:7441110 {source="Europe PMC"} xref: PMID:7689104 {source="Europe PMC"} xref: PMID:8332255 {source="Europe PMC"} xref: PMID:8347173 {source="Europe PMC"} xref: PMID:8679661 {source="Europe PMC"} xref: PMID:9063686 {source="Europe PMC"} xref: PMID:9067318 {source="Europe PMC"} xref: PMID:9132918 {source="Europe PMC"} xref: PMID:9218278 {source="Europe PMC"} xref: Reaxys:17705 {source="Reaxys"} xref: Wikipedia:Caffeine is_a: CHEBI:27134 ! trimethylxanthine is_a: FBcv:0000551 ! enzyme inhibitor is_a: FBcv:0000575 ! caffeine equivalent_to: FBcv:0000575 ! caffeine relationship: has_role CHEBI:176497 ! geroprotector relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:35337 ! central nervous system stimulant relationship: has_role CHEBI:35471 ! psychotropic drug relationship: has_role CHEBI:35498 ! diuretic relationship: has_role CHEBI:35703 ! xenobiotic relationship: has_role CHEBI:50218 ! EC 3.1.4.* (phosphoric diester hydrolase) inhibitor relationship: has_role CHEBI:50925 ! EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor relationship: has_role CHEBI:53121 ! adenosine A2A receptor antagonist relationship: has_role CHEBI:60809 ! adjuvant relationship: has_role CHEBI:64047 ! food additive relationship: has_role CHEBI:67114 ! ryanodine receptor agonist relationship: has_role CHEBI:71232 ! adenosine receptor antagonist relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:76946 ! fungal metabolite relationship: has_role CHEBI:78298 ! environmental contaminant relationship: has_role CHEBI:85234 ! human blood serum metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H10N4O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RYYVLZVUVIJVGH-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "194.19076" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "194.08038" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cn1cnc2n(C)c(=O)n(C)c(=O)c12" xsd:string [Term] id: CHEBI:27789 name: 1,2-dichloroethane namespace: chebi_ontology alt_id: CHEBI:18881 alt_id: CHEBI:49557 alt_id: CHEBI:497 def: "A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2." [] subset: 3_STAR synonym: "1,2-DCE" RELATED [NIST_Chemistry_WebBook] synonym: "1,2-Dichloraethan" RELATED [ChEBI] synonym: "1,2-DICHLOROETHANE" EXACT [PDBeChem] synonym: "1,2-Dichloroethane" EXACT [KEGG_COMPOUND] synonym: "1,2-dichloroethane" EXACT [UniProt] synonym: "1,2-dichloroethane" EXACT IUPAC_NAME [IUPAC] synonym: "Aethylenchlorid" RELATED [ChEBI] synonym: "Aethylendichlorid" RELATED [ChEBI] synonym: "alpha,beta-dichloroethane" RELATED [NIST_Chemistry_WebBook] synonym: "DCE" RELATED [ChemIDplus] synonym: "Dutch liquid" RELATED [KEGG_COMPOUND] synonym: "EDC" RELATED [ChemIDplus] synonym: "ethane dichloride" RELATED [ChemIDplus] synonym: "ethylene chloride" RELATED [ChemIDplus] synonym: "Ethylene dichloride" RELATED [KEGG_COMPOUND] synonym: "Glycol dichloride" RELATED [KEGG_COMPOUND] xref: Beilstein:605264 {source="Beilstein"} xref: CAS:107-06-2 {source="NIST Chemistry WebBook"} xref: CAS:107-06-2 {source="ChemIDplus"} xref: CAS:107-06-2 {source="KEGG COMPOUND"} xref: DrugBank:DB03733 xref: Gmelin:49272 {source="Gmelin"} xref: HMDB:HMDB0029571 xref: KEGG:C06752 xref: MetaCyc:12-DICHLOROETHANE xref: PDBeChem:DCE xref: PMID:17564600 {source="Europe PMC"} xref: PMID:18579268 {source="Europe PMC"} xref: PMID:24228488 {source="Europe PMC"} xref: PMID:24329990 {source="Europe PMC"} xref: PMID:24441515 {source="Europe PMC"} xref: PMID:31520740 {source="Europe PMC"} xref: PMID:32830330 {source="Europe PMC"} xref: PMID:33047531 {source="Europe PMC"} xref: PPDB:2774 xref: Reaxys:605264 {source="Reaxys"} xref: UM-BBD_compID:c0001 {source="UM-BBD"} xref: Wikipedia:1\,2-Dichloroethane is_a: CHEBI:36016 ! chloroethanes is_a: FBcv:0000541 ! intercalating agent is_a: FBcv:0000546 ! 1,2-dichloroethane equivalent_to: FBcv:0000546 ! 1,2-dichloroethane relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:48355 ! non-polar solvent relationship: has_role CHEBI:50908 ! hepatotoxic agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4Cl2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4Cl2/c3-1-2-4/h1-2H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WSLDOOZREJYCGB-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "98.95856" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.96901" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "ClCCCl" xsd:string [Term] id: CHEBI:27899 name: cisplatin namespace: chebi_ontology alt_id: CHEBI:23314 alt_id: CHEBI:3722 def: "A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups)." [] subset: 3_STAR synonym: "(SP-4-2)-diamminedichloridoplatinum" EXACT IUPAC_NAME [IUPAC] synonym: "(SP-4-2)-diamminedichloroplatinum" EXACT IUPAC_NAME [IUPAC] synonym: "[PtCl2(NH3)2]" RELATED [KEGG_COMPOUND] synonym: "Briplatin" RELATED BRAND_NAME [ChemIDplus] synonym: "CDDP" RELATED [KEGG_COMPOUND] synonym: "cis-[PtCl2(NH3)2]" RELATED [MolBase] synonym: "cis-DDP" RELATED [ChemIDplus] synonym: "cis-diamminedichloridoplatinum(II)" EXACT IUPAC_NAME [IUPAC] synonym: "cis-diamminedichloroplatinum" RELATED [ChemIDplus] synonym: "cis-Diamminedichloroplatinum(II)" RELATED [KEGG_COMPOUND] synonym: "cis-diamminedichloroplatinum(II)" EXACT IUPAC_NAME [IUPAC] synonym: "cis-diammineplatinum(II) dichloride" RELATED [ChemIDplus] synonym: "cis-dichlorodiammineplatinum(II)" RELATED [ChemIDplus] synonym: "cis-platin" RELATED [ChEBI] synonym: "Cismaplat" RELATED BRAND_NAME [DrugBank] synonym: "Cisplatin" EXACT [KEGG_COMPOUND] synonym: "cisplatin" RELATED INN [ChemIDplus] synonym: "cisplatine" RELATED INN [ChemIDplus] synonym: "cisplatino" RELATED INN [ChemIDplus] synonym: "cisplatinum" RELATED INN [ChemIDplus] synonym: "Lederplatin" RELATED BRAND_NAME [DrugBank] synonym: "Neoplatin" RELATED BRAND_NAME [DrugBank] synonym: "Peyrone's chloride" RELATED [ChemIDplus] synonym: "Peyrone's salt" RELATED [ChEBI] synonym: "Platamine" RELATED [DrugBank] synonym: "Platinex" RELATED BRAND_NAME [DrugBank] synonym: "Platinol" RELATED BRAND_NAME [KEGG_DRUG] synonym: "Randa" RELATED BRAND_NAME [DrugBank] xref: CAS:15663-27-1 {source="ChemIDplus"} xref: CAS:15663-27-1 {source="KEGG COMPOUND"} xref: DrugBank:DB00515 xref: Gmelin:2519 {source="Gmelin"} xref: HMDB:HMDB0014656 xref: KEGG:C06911 xref: KEGG:D00275 xref: MetaCyc:CPD0-1392 xref: MolBase:25 xref: Patent:DE2318020 xref: Patent:DE2329485 xref: PMID:10883661 {source="Europe PMC"} xref: PMID:12537968 {source="Europe PMC"} xref: PMID:12831510 {source="Europe PMC"} xref: PMID:12935404 {source="Europe PMC"} xref: PMID:16327988 {source="Europe PMC"} xref: PMID:18472761 {source="Europe PMC"} xref: PMID:1855275 {source="Europe PMC"} xref: PMID:23554447 {source="Europe PMC"} xref: PMID:23604226 {source="Europe PMC"} xref: PMID:23651576 {source="Europe PMC"} xref: PMID:28494534 {source="Europe PMC"} xref: Reaxys:11324567 {source="Reaxys"} xref: Wikipedia:Cisplatin is_a: BFO:0000004 ! independent continuant is_a: CHEBI:51214 ! diamminedichloroplatinum is_a: FBcv:0000576 ! cisplatin equivalent_to: FBcv:0000576 ! cisplatin relationship: has_role CHEBI:173085 ! ferroptosis inducer relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:35610 ! antineoplastic agent relationship: has_role CHEBI:47868 ! photosensitizing agent relationship: has_role CHEBI:50684 ! cross-linking reagent relationship: has_role CHEBI:50902 ! genotoxin relationship: has_role CHEBI:61015 ! nephrotoxin relationship: has_role CHEBI:68495 ! apoptosis inducer property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Cl2H6N2Pt" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H6Cl2N2Pt" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LXZZYRPGZAFOLE-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "300.04452" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "298.95560" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H]" xsd:string [Term] id: CHEBI:27919 name: tretamine namespace: chebi_ontology alt_id: CHEBI:27109 alt_id: CHEBI:9708 subset: 3_STAR synonym: "2,4,6-tri(1-aziridinyl)-1,3,5-triazine" RELATED [NIST_Chemistry_WebBook] synonym: "2,4,6-tri(aziridin-1-yl)-1,3,5-triazine" EXACT IUPAC_NAME [IUPAC] synonym: "2,4,6-tris(1-aziridinyl)-1,3,5-triazine" RELATED [NIST_Chemistry_WebBook] synonym: "2,4,6-tris(1-aziridinyl)-s-triazine" RELATED [NIST_Chemistry_WebBook] synonym: "2,4,6-tris(aziridin-1-yl)-1,3,5-triazine" RELATED [ChEBI] synonym: "TEM" RELATED [ChEBI] synonym: "tretamine" EXACT [ChemIDplus] synonym: "Triethylenemelamine" RELATED [KEGG_COMPOUND] synonym: "Trisaziridinyltriazine" RELATED [KEGG_COMPOUND] xref: Beilstein:242245 {source="Beilstein"} xref: CAS:51-18-3 {source="KEGG COMPOUND"} xref: CAS:51-18-3 {source="ChemIDplus"} xref: CAS:51-18-3 {source="NIST Chemistry WebBook"} xref: Drug_Central:2739 {source="DrugCentral"} xref: KEGG:C07642 xref: Reaxys:242245 {source="Reaxys"} is_a: CHEBI:26588 ! 1,3,5-triazines is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000605 ! triethylenemelamine equivalent_to: FBcv:0000605 ! triethylenemelamine relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:67105 ! insect sterilant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H12N6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H12N6/c1-2-13(1)7-10-8(14-3-4-14)12-9(11-7)15-5-6-15/h1-6H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IUCJMVBFZDHPDX-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "204.23202" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "204.11234" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1CN1c1nc(nc(n1)N1CC1)N1CC1" xsd:string [Term] id: CHEBI:28044 name: phenylalanine namespace: chebi_ontology alt_id: CHEBI:25984 alt_id: CHEBI:8089 def: "An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group." [] subset: 3_STAR synonym: "2-amino-3-phenylpropanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "alpha-Amino-beta-phenylpropionic acid" RELATED [KEGG_COMPOUND] synonym: "DL-Phenylalanine" RELATED [KEGG_COMPOUND] synonym: "F" RELATED [ChEBI] synonym: "fenilalanina" RELATED [ChEBI] synonym: "PHE" RELATED [ChEBI] synonym: "Phenylalanin" RELATED [ChEBI] synonym: "Phenylalanine" EXACT [KEGG_COMPOUND] synonym: "phenylalanine" EXACT [ChEBI] synonym: "phenylalanine" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:1910407 {source="Beilstein"} xref: CAS:150-30-1 {source="ChemIDplus"} xref: CAS:150-30-1 {source="NIST Chemistry WebBook"} xref: Gmelin:50836 {source="Gmelin"} xref: KEGG:C02057 xref: PMID:17439666 {source="Europe PMC"} xref: PMID:22264337 {source="Europe PMC"} xref: Reaxys:1910407 {source="Reaxys"} xref: Wikipedia:Phenylalanine is_a: CHEBI:33704 ! alpha-amino acid is_a: CHEBI:33856 ! aromatic amino acid relationship: has_part CHEBI:22744 ! benzyl group relationship: has_role CHEBI:83056 ! Daphnia magna metabolite relationship: is_conjugate_acid_of CHEBI:32504 ! phenylalaninate relationship: is_conjugate_base_of CHEBI:32505 ! phenylalaninium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H11NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "165.18918" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "165.07898" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(Cc1ccccc1)C(O)=O" xsd:string [Term] id: CHEBI:28230 name: hesperetin namespace: chebi_ontology alt_id: CHEBI:24529 alt_id: CHEBI:5681 def: "A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position." [] subset: 3_STAR synonym: "(-)-(S)-hesperetin" RELATED [ChEBI] synonym: "(-)-hesperetin" RELATED [ChEBI] synonym: "(2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one" EXACT IUPAC_NAME [IUPAC] synonym: "(2S)-hesperetin" RELATED [UniProt] synonym: "(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one" RELATED [ChEBI] synonym: "3',5,7-Trihydroxy-4'-methoxyflavanone" RELATED [KEGG_COMPOUND] synonym: "Hesperetin" EXACT [KEGG_COMPOUND] xref: Beilstein:92705 {source="Beilstein"} xref: CAS:520-33-2 {source="ChemIDplus"} xref: CAS:520-33-2 {source="KEGG COMPOUND"} xref: Drug_Central:1362 {source="DrugCentral"} xref: DrugBank:DB01094 xref: HMDB:HMDB0005782 xref: KEGG:C01709 xref: KNApSAcK:C00000968 xref: LINCS:LSM-20933 xref: LIPID_MAPS_instance:LMPK12140003 {source="LIPID MAPS"} xref: MetaCyc:CPD-7072 xref: PMID:16964766 {source="Europe PMC"} xref: PMID:22409373 {source="Europe PMC"} xref: PMID:22794525 {source="Europe PMC"} xref: PMID:22899565 {source="Europe PMC"} xref: PMID:22903244 {source="Europe PMC"} xref: Reaxys:92705 {source="Reaxys"} xref: Wikipedia:Hesperetin is_a: BFO:0000004 ! independent continuant is_a: CHEBI:140332 ! 4'-methoxyflavanones is_a: CHEBI:38738 ! monomethoxyflavanone is_a: CHEBI:38739 ! trihydroxyflavanone is_a: CHEBI:48024 ! 3'-hydroxyflavanones relationship: has_role CHEBI:22586 ! antioxidant relationship: has_role CHEBI:35610 ! antineoplastic agent relationship: has_role CHEBI:76924 ! plant metabolite relationship: is_conjugate_acid_of CHEBI:61249 ! hesperetin(1-) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C16H14O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3/t14-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "AIONOLUJZLIMTK-AWEZNQCLSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "302.27880" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "302.07904" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1" xsd:string [Term] id: CHEBI:28262 name: dimethyl sulfoxide namespace: chebi_ontology alt_id: CHEBI:23801 alt_id: CHEBI:42138 alt_id: CHEBI:4612 def: "A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents." [] subset: 3_STAR synonym: "(CH3)2SO" RELATED [NIST_Chemistry_WebBook] synonym: "(methanesulfinyl)methane" EXACT IUPAC_NAME [IUPAC] synonym: "DIMETHYL SULFOXIDE" EXACT [PDBeChem] synonym: "Dimethyl sulfoxide" EXACT [KEGG_COMPOUND] synonym: "dimethyl sulfoxide" EXACT [UniProt] synonym: "dimethyl sulfoxide" EXACT IUPAC_NAME [IUPAC] synonym: "dimethyl sulfoxide" RELATED INN [ChemIDplus] synonym: "dimethyl sulfur oxide" RELATED [NIST_Chemistry_WebBook] synonym: "dimethyl sulphoxide" RELATED [ChemIDplus] synonym: "dimethyli sulfoxidum" RELATED INN [ChemIDplus] synonym: "Dimethylsulfoxid" RELATED [ChEBI] synonym: "dimethylsulfoxyde" RELATED INN [ChemIDplus] synonym: "dimetil sulfoxido" RELATED INN [ChemIDplus] synonym: "DMSO" RELATED [KEGG_COMPOUND] synonym: "dmso" RELATED [IUPAC] synonym: "methylsulfinylmethane" RELATED [ChemIDplus] synonym: "S(O)Me2" RELATED [ChEBI] synonym: "sulfinylbis(methane)" RELATED [ChemIDplus] xref: Beilstein:506008 {source="Beilstein"} xref: CAS:67-68-5 {source="NIST Chemistry WebBook"} xref: CAS:67-68-5 {source="ChemIDplus"} xref: CAS:67-68-5 {source="KEGG COMPOUND"} xref: Chemspider:659 xref: Drug_Central:906 {source="DrugCentral"} xref: DrugBank:DB01093 xref: FooDB:FDB000764 xref: Gmelin:1556 {source="Gmelin"} xref: HMDB:HMDB0002151 xref: KEGG:C11143 xref: KEGG:D01043 xref: KNApSAcK:C00053120 xref: LINCS:LSM-36361 xref: MetaCyc:DMSO xref: PDBeChem:DMS xref: PMID:10298633 {source="Europe PMC"} xref: PMID:11162043 {source="Europe PMC"} xref: PMID:11350866 {source="Europe PMC"} xref: PMID:11474739 {source="Europe PMC"} xref: PMID:12663039 {source="Europe PMC"} xref: PMID:15237653 {source="Europe PMC"} xref: PMID:15588915 {source="Europe PMC"} xref: PMID:15868171 {source="Europe PMC"} xref: PMID:16434015 {source="Europe PMC"} xref: PMID:16522014 {source="Europe PMC"} xref: PMID:19096138 {source="Europe PMC"} xref: PMID:19382398 {source="Europe PMC"} xref: PMID:19443933 {source="Europe PMC"} xref: PMID:21426213 {source="Europe PMC"} xref: PMID:22030943 {source="Europe PMC"} xref: PMID:22722716 {source="Europe PMC"} xref: PMID:22768202 {source="Europe PMC"} xref: PMID:22814967 {source="Europe PMC"} xref: PMID:23050031 {source="Europe PMC"} xref: PMID:28220525 {source="Europe PMC"} xref: PMID:29938311 {source="Europe PMC"} xref: PMID:31489176 {source="Europe PMC"} xref: PMID:3510103 {source="Europe PMC"} xref: PMID:3898376 {source="Europe PMC"} xref: PMID:3916302 {source="Europe PMC"} xref: PMID:4223708 {source="Europe PMC"} xref: PMID:4556944 {source="Europe PMC"} xref: PMID:4963226 {source="Europe PMC"} xref: PMID:6309056 {source="Europe PMC"} xref: PMID:6379027 {source="Europe PMC"} xref: Reaxys:506008 {source="Reaxys"} xref: UM-BBD_compID:c0236 {source="UM-BBD"} xref: Wikipedia:Dimethyl_sulfoxide is_a: CHEBI:134179 ! volatile organic compound is_a: CHEBI:22063 ! sulfoxide is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000578 ! dimethyl sulfoxide equivalent_to: FBcv:0000578 ! dimethyl sulfoxide relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:35481 ! non-narcotic analgesic relationship: has_role CHEBI:37335 ! MRI contrast agent relationship: has_role CHEBI:48358 ! polar aprotic solvent relationship: has_role CHEBI:48578 ! radical scavenger relationship: has_role CHEBI:50247 ! antidote relationship: has_role CHEBI:76971 ! Escherichia coli metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H6OS" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H6OS/c1-4(2)3/h1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IAZDPXIOMUYVGZ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "78.13444" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "78.01394" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CS(C)=O" xsd:string [Term] id: CHEBI:28534 name: 1,2-dibromoethane namespace: chebi_ontology alt_id: CHEBI:18880 alt_id: CHEBI:496 def: "A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae." [] subset: 3_STAR synonym: "1,2-Dibromoethane" EXACT [KEGG_COMPOUND] synonym: "1,2-dibromoethane" EXACT [UniProt] synonym: "1,2-dibromoethane" EXACT IUPAC_NAME [IUPAC] synonym: "alpha,beta-dibromoethane" RELATED [NIST_Chemistry_WebBook] synonym: "alpha,omega-dibromoethane" RELATED [ChemIDplus] synonym: "DBE" RELATED [NIST_Chemistry_WebBook] synonym: "EDB" RELATED [NIST_Chemistry_WebBook] synonym: "ethylene bromide" RELATED [NIST_Chemistry_WebBook] synonym: "Ethylene dibromide" RELATED [KEGG_COMPOUND] synonym: "sym-Dibromoethane" RELATED [ChemIDplus] xref: Beilstein:605266 {source="Beilstein"} xref: CAS:106-93-4 {source="NIST Chemistry WebBook"} xref: CAS:106-93-4 {source="ChemIDplus"} xref: CAS:106-93-4 {source="KEGG COMPOUND"} xref: Gmelin:1913 {source="Gmelin"} xref: HMDB:HMDB0060334 xref: KEGG:C11088 xref: MetaCyc:12-DIBROMOETHANE xref: PMID:10088182 {source="Europe PMC"} xref: PMID:11312844 {source="Europe PMC"} xref: PPDB:1484 xref: Reaxys:605266 {source="Reaxys"} xref: Wikipedia:1\,2-Dibromoethane is_a: CHEBI:22926 ! bromohydrocarbon is_a: CHEBI:22929 ! bromoalkane is_a: FBcv:0000541 ! intercalating agent is_a: FBcv:0000545 ! 1,2-dibromoethane equivalent_to: FBcv:0000545 ! 1,2-dibromoethane relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:39276 ! fumigant relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76507 ! marine metabolite relationship: has_role CHEBI:84735 ! algal metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4Br2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4Br2/c3-1-2-4/h1-2H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "PAAZPARNPHGIKF-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "187.86116" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "185.86798" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "BrCCBr" xsd:string [Term] id: CHEBI:28616 name: carbamic acid namespace: chebi_ontology alt_id: CHEBI:22504 alt_id: CHEBI:23002 alt_id: CHEBI:3386 alt_id: CHEBI:44573 def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." [] subset: 3_STAR synonym: "Aminoameisensaeure" RELATED [ChEBI] synonym: "Aminoformic acid" RELATED [KEGG_COMPOUND] synonym: "Carbamate" RELATED [KEGG_COMPOUND] synonym: "CARBAMIC ACID" EXACT [PDBeChem] synonym: "Carbamic acid" EXACT [KEGG_COMPOUND] synonym: "carbamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Carbamidsaeure" RELATED [ChEBI] xref: Beilstein:1734754 {source="Beilstein"} xref: CAS:463-77-4 {source="KEGG COMPOUND"} xref: CAS:463-77-4 {source="ChemIDplus"} xref: DrugBank:DB04261 xref: Gmelin:130345 {source="Gmelin"} xref: KEGG:C01563 xref: PDBeChem:OUT xref: Wikipedia:Carbamic_acid is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:64708 ! one-carbon compound relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_acid_of CHEBI:13941 ! carbamate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "61.04006" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "61.01638" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(O)=O" xsd:string [Term] id: CHEBI:28659 name: phosphorus atom namespace: chebi_ontology alt_id: CHEBI:26080 alt_id: CHEBI:8168 subset: 3_STAR synonym: "15P" RELATED [IUPAC] synonym: "fosforo" RELATED [ChEBI] synonym: "P" RELATED [IUPAC] synonym: "P" RELATED [KEGG_COMPOUND] synonym: "Phosphor" RELATED [ChEBI] synonym: "phosphore" RELATED [ChEBI] synonym: "Phosphorus" RELATED [KEGG_COMPOUND] synonym: "phosphorus" EXACT IUPAC_NAME [IUPAC] synonym: "phosphorus" RELATED [ChEBI] xref: CAS:7723-14-0 {source="ChemIDplus"} xref: CAS:7723-14-0 {source="KEGG COMPOUND"} xref: Gmelin:16235 {source="Gmelin"} xref: KEGG:C06262 xref: WebElements:P is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OAICVXFJPJFONN-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "30.97376" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "30.97376" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[P]" xsd:string [Term] id: CHEBI:28694 name: copper atom namespace: chebi_ontology alt_id: CHEBI:23376 alt_id: CHEBI:3874 subset: 3_STAR synonym: "29Cu" RELATED [IUPAC] synonym: "cobre" RELATED [ChEBI] synonym: "Copper" RELATED [KEGG_COMPOUND] synonym: "copper" EXACT IUPAC_NAME [IUPAC] synonym: "copper" RELATED [ChEBI] synonym: "Cu" RELATED [ChEBI] synonym: "Cu" RELATED [IUPAC] synonym: "cuivre" RELATED [ChEBI] synonym: "cuprum" RELATED [IUPAC] synonym: "Kupfer" RELATED [ChEBI] xref: CAS:7440-50-8 {source="ChemIDplus"} xref: CAS:7440-50-8 {source="KEGG COMPOUND"} xref: Gmelin:16269 {source="Gmelin"} xref: KEGG:C00070 xref: WebElements:Cu is_a: CHEBI:33366 ! copper group element atom is_a: CHEBI:88184 ! metal allergen relationship: has_role CHEBI:27027 ! micronutrient relationship: has_role CHEBI:76971 ! Escherichia coli metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Cu" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Cu" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RYGMFSIKBFXOCR-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "63.54600" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.92960" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Cu]" xsd:string [Term] id: CHEBI:28741 name: sodium fluoride namespace: chebi_ontology alt_id: CHEBI:26713 alt_id: CHEBI:9178 def: "A metal fluoride salt with a Na(+) counterion." [] subset: 3_STAR synonym: "NaF" RELATED [IUPAC] synonym: "Sodium fluoride" EXACT [KEGG_COMPOUND] synonym: "sodium fluoride" EXACT IUPAC_NAME [IUPAC] xref: CAS:7681-49-4 {source="KEGG COMPOUND"} xref: CAS:7681-49-4 {source="ChemIDplus"} xref: KEGG:C08142 xref: KEGG:D00943 xref: Wikipedia:Sodium_Fluoride is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24060 ! fluoride salt is_a: CHEBI:24835 ! inorganic molecular entity is_a: FBcv:0000553 ! inorganic compound is_a: FBcv:0000557 ! sodium fluoride equivalent_to: FBcv:0000557 ! sodium fluoride relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "FNa" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Na.F" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/FH.Na/h1H;/q;+1/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "PUZPDOWCWNUUKD-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "41.98817" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "41.98817" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[F-].[Na+]" xsd:string [Term] id: CHEBI:28775 name: hesperidin namespace: chebi_ontology alt_id: CHEBI:24530 alt_id: CHEBI:5682 def: "A disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage." [] subset: 3_STAR synonym: "(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside" EXACT IUPAC_NAME [IUPAC] synonym: "(2S)-hesperidin" RELATED [UniProt] synonym: "(S)-(-)-hesperidin" RELATED [ChemIDplus] synonym: "Cirantin" RELATED [ChemIDplus] synonym: "Ciratin" RELATED [KEGG_COMPOUND] synonym: "Hesperetin 7-O-rutinoside" RELATED [KEGG_COMPOUND] synonym: "Hesperidin" EXACT [KEGG_COMPOUND] synonym: "Hesperidoside" RELATED [ChemIDplus] xref: Beilstein:75140 {source="Beilstein"} xref: CAS:520-26-3 {source="KEGG COMPOUND"} xref: CAS:520-26-3 {source="ChemIDplus"} xref: DrugBank:DB04703 xref: HMDB:HMDB0003265 xref: KEGG:C09755 xref: KEGG:D01038 xref: KNApSAcK:C00000970 xref: LINCS:LSM-2858 xref: MetaCyc:CPD-7075 xref: Reaxys:75140 {source="Reaxys"} xref: Wikipedia:Hesperidin is_a: BFO:0000004 ! independent continuant is_a: CHEBI:140332 ! 4'-methoxyflavanones is_a: CHEBI:26587 ! rutinoside is_a: CHEBI:38738 ! monomethoxyflavanone is_a: CHEBI:38749 ! dihydroxyflavanone is_a: CHEBI:48024 ! 3'-hydroxyflavanones is_a: CHEBI:63353 ! disaccharide derivative is_a: CHEBI:72730 ! flavanone glycoside is_a: FBcv:0000585 ! hesperidine equivalent_to: FBcv:0000585 ! hesperidine relationship: has_functional_parent CHEBI:28230 ! hesperetin relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C28H34O15" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QUQPHWDTPGMPEX-QJBIFVCTSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "610.56056" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "610.18977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1" xsd:string [Term] id: CHEBI:28830 name: chlorambucil namespace: chebi_ontology alt_id: CHEBI:25817 alt_id: CHEBI:3601 alt_id: CHEBI:48770 def: "A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia." [] subset: 3_STAR synonym: "4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid" RELATED [NIST_Chemistry_WebBook] synonym: "4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid" RELATED [NIST_Chemistry_WebBook] synonym: "4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Ambochlorin" RELATED [NIST_Chemistry_WebBook] synonym: "CHLORAMBUCIL" EXACT [PDBeChem] synonym: "Chlorambucil" EXACT [KEGG_DRUG] synonym: "chloraminophen" RELATED [ChemIDplus] synonym: "gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid" RELATED [NIST_Chemistry_WebBook] synonym: "Leukeran" RELATED [NIST_Chemistry_WebBook] synonym: "N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid" RELATED [NIST_Chemistry_WebBook] synonym: "phenylbutyric acid nitrogen mustard" RELATED [ChemIDplus] xref: Beilstein:999011 {source="Beilstein"} xref: CAS:305-03-3 {source="ChemIDplus"} xref: CAS:305-03-3 {source="NIST Chemistry WebBook"} xref: Drug_Central:588 {source="DrugCentral"} xref: DrugBank:DB00291 xref: KEGG:D00266 xref: LINCS:LSM-2645 xref: PDBeChem:CBL xref: PMID:22025197 {source="Europe PMC"} xref: PMID:22978684 {source="Europe PMC"} xref: PMID:23233721 {source="Europe PMC"} xref: PMID:23295789 {source="Europe PMC"} xref: PMID:23521128 {source="Europe PMC"} xref: PMID:23665800 {source="Europe PMC"} xref: PMID:23667729 {source="Europe PMC"} xref: PMID:23683018 {source="Europe PMC"} xref: PMID:23725434 {source="Europe PMC"} xref: PMID:23822827 {source="Europe PMC"} xref: PMID:24098639 {source="Europe PMC"} xref: PMID:24147900 {source="Europe PMC"} xref: PMID:24223689 {source="Europe PMC"} xref: Reaxys:999011 {source="Reaxys"} xref: Wikipedia:Chlorambucil is_a: CHEBI:25384 ! monocarboxylic acid is_a: CHEBI:33860 ! aromatic amine is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:37598 ! nitrogen mustard is_a: CHEBI:50996 ! tertiary amino compound is_a: FBcv:0000813 ! nitrogen mustard is_a: FBcv:0000815 ! p-N,N-di-(2-chloroethyl)aminophenylbutyric acid equivalent_to: FBcv:0000815 ! p-N,N-di-(2-chloroethyl)aminophenylbutyric acid relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:35610 ! antineoplastic agent relationship: has_role CHEBI:35705 ! immunosuppressive agent relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:88188 ! drug allergen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C14H19Cl2NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JCKYGMPEJWAADB-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "304.21160" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "303.07928" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl" xsd:string [Term] id: CHEBI:28863 name: flavanones namespace: chebi_ontology alt_id: CHEBI:13636 alt_id: CHEBI:24038 alt_id: CHEBI:24054 def: "Members of the class of flavans with a 3,4-dihydro-2-aryl-2H-1-benzopyran-4-one skeleton and its substituted derivatives." [] subset: 3_STAR synonym: "2,3-dihydroflavones" RELATED [ChEBI] synonym: "a flavanone" RELATED [UniProt] xref: MetaCyc:FLAVANONES xref: Wikipedia:Flavanone is_a: CHEBI:38672 ! flavans is_a: CHEBI:3992 ! cyclic ketone property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C15H2O2R10" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "214.176" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "214.00548" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O1C2=C(C(C(C1C3=C(C(=C(C(=C3*)*)*)*)*)*)=O)C(=C(C(=C2*)*)*)*" xsd:string [Term] id: CHEBI:28868 name: fatty acid anion namespace: chebi_ontology alt_id: CHEBI:13634 alt_id: CHEBI:24022 alt_id: CHEBI:4985 def: "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." [] subset: 3_STAR synonym: "a fatty acid" RELATED [UniProt] synonym: "acido graso anionico" RELATED [ChEBI] synonym: "acidos grasos anionicos" RELATED [ChEBI] synonym: "Alkanate" RELATED [KEGG_COMPOUND] synonym: "anion de l'acide gras" RELATED [ChEBI] synonym: "Fatty acid anion" EXACT [KEGG_COMPOUND] synonym: "fatty acid anions" RELATED [ChEBI] synonym: "Fettsaeureanion" RELATED [ChEBI] synonym: "Fettsaeureanionen" RELATED [ChEBI] xref: KEGG:C02403 xref: PMID:18628202 {source="Europe PMC"} is_a: CHEBI:18059 ! lipid is_a: CHEBI:35757 ! monocarboxylic acid anion relationship: is_conjugate_base_of CHEBI:35366 ! fatty acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.00950" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:28876 name: melphalan namespace: chebi_ontology alt_id: CHEBI:25815 alt_id: CHEBI:6742 def: "A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring." [] subset: 3_STAR synonym: "3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine" RELATED [ChemIDplus] synonym: "3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine" RELATED [ChemIDplus] synonym: "4-(Bis(2-chloroethyl)amino)-L-phenylalanine" RELATED [ChemIDplus] synonym: "4-[bis(2-chloroethyl)amino]-L-phenylalanine" EXACT IUPAC_NAME [IUPAC] synonym: "L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine" RELATED [ChemIDplus] synonym: "L-PAM" RELATED [ChemIDplus] synonym: "L-Phenylalanine mustard" RELATED [ChemIDplus] synonym: "L-Sarcolysine" RELATED [ChemIDplus] synonym: "melfalano" RELATED INN [ChemIDplus] synonym: "melphalan" RELATED INN [KEGG_DRUG] synonym: "melphalanum" RELATED INN [ChemIDplus] synonym: "p-Bis(beta-chloroethyl)aminophenylalanine" RELATED [ChemIDplus] synonym: "p-Di-(2-chloroethyl)amino-L-phenylalanine" RELATED [ChemIDplus] synonym: "p-L-Sarcolysin" RELATED [ChemIDplus] synonym: "p-N,N-bis(2-chloroethyl)amino-L-phenylalanine" RELATED [ChEBI] synonym: "p-N-Bis(2-chloroethyl)amino-L-phenylalanine" RELATED [ChemIDplus] synonym: "Phenylalanine mustard" RELATED [ChemIDplus] synonym: "Phenylalanine nitrogen mustard" RELATED [ChemIDplus] xref: CAS:148-82-3 {source="KEGG DRUG"} xref: CAS:148-82-3 {source="ChemIDplus"} xref: Drug_Central:1678 {source="DrugCentral"} xref: DrugBank:DB01042 xref: KEGG:D00369 xref: Patent:US108552 xref: Patent:US275057 xref: Patent:US3032584 xref: Patent:US3032585 xref: PMID:10820424 {source="Europe PMC"} xref: PMID:10937717 {source="Europe PMC"} xref: PMID:11680815 {source="Europe PMC"} xref: PMID:11914777 {source="Europe PMC"} xref: PMID:18481314 {source="Europe PMC"} xref: PMID:445303 {source="Europe PMC"} xref: PMID:7494795 {source="Europe PMC"} xref: PMID:7605343 {source="Europe PMC"} xref: PMID:8552138 {source="Europe PMC"} xref: PMID:8951232 {source="Europe PMC"} xref: PMID:9218926 {source="Europe PMC"} xref: PMID:9250538 {source="Europe PMC"} xref: Reaxys:2816456 {source="Reaxys"} xref: Wikipedia:Melphalan is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:37598 ! nitrogen mustard is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid is_a: CHEBI:84144 ! L-phenylalanine derivative is_a: FBcv:0000596 ! p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine is_a: FBcv:0000813 ! nitrogen mustard equivalent_to: FBcv:0000596 ! p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:35610 ! antineoplastic agent relationship: has_role CHEBI:35705 ! immunosuppressive agent relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:88188 ! drug allergen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C13H18Cl2N2O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SGDBTWWWUNNDEQ-LBPRGKRZSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "305.20000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "304.07453" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O" xsd:string [Term] id: CHEBI:28901 name: busulfan namespace: chebi_ontology alt_id: CHEBI:18936 alt_id: CHEBI:3225 def: "A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant." [] subset: 3_STAR synonym: "1,4-Bis(methanesulfonoxy)butane" RELATED [ChemIDplus] synonym: "1,4-Butanediol dimethanesulfonate" RELATED [ChemIDplus] synonym: "1,4-Dimesyloxybutane" RELATED [ChemIDplus] synonym: "1,4-Dimethanesulfonoxybutane" RELATED [ChemIDplus] synonym: "Bisulfex" RELATED BRAND_NAME [ChEBI] synonym: "Busulfan" EXACT [KEGG_DRUG] synonym: "busulfan" RELATED INN [WHO_MedNet] synonym: "busulfano" RELATED INN [WHO_MedNet] synonym: "busulfanum" RELATED INN [WHO_MedNet] synonym: "butane-1,4-diyl dimethanesulfonate" EXACT IUPAC_NAME [IUPAC] synonym: "Leucosulfan" RELATED BRAND_NAME [ChEBI] synonym: "Mablin" RELATED BRAND_NAME [ChEBI] synonym: "Mielucin" RELATED BRAND_NAME [ChEBI] synonym: "Misulban" RELATED BRAND_NAME [ChEBI] synonym: "Mitostan" RELATED BRAND_NAME [ChEBI] synonym: "Myeloleukon" RELATED BRAND_NAME [ChEBI] synonym: "Myleran" RELATED BRAND_NAME [KEGG_DRUG] synonym: "Tetramethylene bis(methanesulfonate)" RELATED [ChemIDplus] xref: Beilstein:1791786 {source="Beilstein"} xref: CAS:55-98-1 {source="ChemIDplus"} xref: CAS:55-98-1 {source="KEGG DRUG"} xref: Drug_Central:438 {source="DrugCentral"} xref: DrugBank:DB01008 xref: KEGG:C06862 xref: KEGG:D00248 xref: LINCS:LSM-5388 xref: Patent:US2917432 xref: PMID:10523796 {source="Europe PMC"} xref: PMID:19361744 {source="Europe PMC"} xref: PMID:19611402 {source="Europe PMC"} xref: Reaxys:1791786 {source="Reaxys"} xref: Wikipedia:Busulfan is_a: CHEBI:25223 ! methanesulfonate ester is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000814 ! 1,4-dimethanesulfonoxybutane equivalent_to: FBcv:0000814 ! 1,4-dimethanesulfonoxybutane relationship: has_functional_parent CHEBI:41189 ! butane-1,4-diol relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:35610 ! antineoplastic agent relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:50905 ! teratogenic agent relationship: has_role CHEBI:67105 ! insect sterilant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H14O6S2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COVZYZSDYWQREU-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "246.30200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "246.02318" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CS(=O)(=O)OCCCCOS(C)(=O)=O" xsd:string [Term] id: CHEBI:28938 name: ammonium namespace: chebi_ontology alt_id: CHEBI:22534 alt_id: CHEBI:49783 alt_id: CHEBI:7435 def: "An onium cation obtained by protonation of ammonia." [] subset: 3_STAR synonym: "[NH4](+)" RELATED [MolBase] synonym: "ammonium" EXACT IUPAC_NAME [IUPAC] synonym: "ammonium" EXACT [ChEBI] synonym: "ammonium cation" RELATED [ChemIDplus] synonym: "ammonium ion" RELATED [PDBeChem] synonym: "Ammonium(1+)" RELATED [ChemIDplus] synonym: "azanium" EXACT IUPAC_NAME [IUPAC] synonym: "NH4(+)" RELATED [UniProt] synonym: "NH4(+)" RELATED [IUPAC] synonym: "NH4+" RELATED [KEGG_COMPOUND] xref: CAS:14798-03-9 {source="NIST Chemistry WebBook"} xref: CAS:14798-03-9 {source="ChemIDplus"} xref: Gmelin:84 {source="Gmelin"} xref: KEGG:C01342 xref: MetaCyc:AMMONIUM xref: MolBase:929 xref: PDBeChem:NH4 xref: PMID:11319011 {source="Europe PMC"} xref: PMID:11341317 {source="Europe PMC"} xref: PMID:12096804 {source="Europe PMC"} xref: PMID:14512268 {source="Europe PMC"} xref: PMID:14879753 {source="Europe PMC"} xref: PMID:16345391 {source="Europe PMC"} xref: PMID:16903292 {source="Europe PMC"} xref: PMID:17392693 {source="Europe PMC"} xref: PMID:18515490 {source="Europe PMC"} xref: PMID:19199063 {source="Europe PMC"} xref: PMID:19596600 {source="Europe PMC"} xref: PMID:19682559 {source="Europe PMC"} xref: PMID:19716251 {source="Europe PMC"} xref: PMID:21993530 {source="Europe PMC"} xref: PMID:22265469 {source="Europe PMC"} xref: PMID:22524020 {source="Europe PMC"} xref: PMID:22562341 {source="Europe PMC"} xref: PMID:22631217 {source="Europe PMC"} xref: Reaxys:16093784 {source="Reaxys"} xref: Wikipedia:Ammonium is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:50313 ! onium cation is_a: CHEBI:60242 ! monovalent inorganic cation relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:16134 ! ammonia property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H4N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "18.03850" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.03383" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N+]([H])([H])[H]" xsd:string [Term] id: CHEBI:28954 name: fagaronine namespace: chebi_ontology alt_id: CHEBI:24011 alt_id: CHEBI:4968 subset: 3_STAR synonym: "2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridinium" EXACT IUPAC_NAME [IUPAC] synonym: "Fagaronine" EXACT [KEGG_COMPOUND] xref: CAS:52259-65-1 {source="KEGG COMPOUND"} xref: KEGG:C09438 xref: KNApSAcK:C00001857 is_a: CHEBI:38517 ! benzophenanthridine alkaloid is_a: FBcv:0000583 ! fagaronine equivalent_to: FBcv:0000583 ! fagaronine relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H20NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C21H19NO4/c1-22-11-13-8-19(25-3)20(26-4)9-15(13)14-6-5-12-7-17(23)18(24-2)10-16(12)21(14)22/h5-11H,1-4H3/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OOKZVPUCASIEBL-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "350.38784" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "350.13868" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COc1cc2c(ccc3c4cc(OC)c(OC)cc4c[n+](C)c23)cc1O" xsd:string [Term] id: CHEBI:28965 name: dicarboxylic acid dianion namespace: chebi_ontology alt_id: CHEBI:13632 alt_id: CHEBI:23688 alt_id: CHEBI:23689 alt_id: CHEBI:38711 def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." [] subset: 3_STAR synonym: "a dicarboxylate" RELATED [UniProt] synonym: "dicarboxylate" RELATED [ChEBI] synonym: "dicarboxylates" RELATED [ChEBI] synonym: "dicarboxylic acid dianion" EXACT [ChEBI] synonym: "dicarboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:35693 ! dicarboxylic acid anion is_a: CHEBI:38716 ! carboxylic acid dianion property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2O4R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "88.019" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.97966" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C(=O)[*]C([O-])=O" xsd:string [Term] id: CHEBI:28976 name: carbonic acid namespace: chebi_ontology alt_id: CHEBI:13351 alt_id: CHEBI:23017 alt_id: CHEBI:23744 alt_id: CHEBI:3401 subset: 3_STAR synonym: "[CO(OH)2]" RELATED [IUPAC] synonym: "Carbonic acid" EXACT [KEGG_COMPOUND] synonym: "carbonic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Dihydrogen carbonate" RELATED [KEGG_COMPOUND] synonym: "dihydroxidooxidocarbon" EXACT IUPAC_NAME [IUPAC] synonym: "H2CO3" RELATED [KEGG_COMPOUND] synonym: "H2CO3" RELATED [IUPAC] synonym: "Koehlensaeure" RELATED [ChEBI] xref: CAS:463-79-6 {source="ChemIDplus"} xref: CAS:463-79-6 {source="KEGG COMPOUND"} xref: Gmelin:25554 {source="Gmelin"} xref: KEGG:C01353 xref: PDBeChem:CO3 is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36961 ! chalcocarbonic acid relationship: has_role CHEBI:75771 ! mouse metabolite relationship: is_conjugate_acid_of CHEBI:17544 ! hydrogencarbonate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "62.02478" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.00039" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(O)=O" xsd:string [Term] id: CHEBI:29036 name: copper(2+) namespace: chebi_ontology alt_id: CHEBI:20882 alt_id: CHEBI:23380 alt_id: CHEBI:49550 def: "An ion of copper carrying a double positive charge." [] subset: 3_STAR synonym: "COPPER (II) ION" RELATED [PDBeChem] synonym: "copper(2+)" EXACT IUPAC_NAME [IUPAC] synonym: "copper(2+) ion" EXACT IUPAC_NAME [IUPAC] synonym: "copper(II) cation" EXACT IUPAC_NAME [IUPAC] synonym: "copper(II) cation" RELATED [ChEBI] synonym: "copper, ion (Cu2+)" RELATED [ChemIDplus] synonym: "Cu(2+)" RELATED [UniProt] synonym: "Cu(II)" RELATED [ChEBI] synonym: "Cu2+" RELATED [ChEBI] synonym: "cupric ion" RELATED [ChEBI] xref: CAS:15158-11-9 {source="ChemIDplus"} xref: Gmelin:6855 {source="Gmelin"} xref: PDBeChem:CU xref: PMID:23900424 {source="Europe PMC"} xref: PMID:24168430 {source="Europe PMC"} xref: Reaxys:3587177 {source="Reaxys"} is_a: CHEBI:23378 ! copper cation is_a: CHEBI:30412 ! monoatomic dication is_a: CHEBI:60240 ! divalent metal cation relationship: has_role CHEBI:23357 ! cofactor property_value: http://purl.obolibrary.org/obo/chebi/charge "+2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Cu" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Cu/q+2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JPVYNHNXODAKFH-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "63.54600" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.92850" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Cu++]" xsd:string [Term] id: CHEBI:29067 name: carboxylic acid anion namespace: chebi_ontology alt_id: CHEBI:13626 alt_id: CHEBI:13945 alt_id: CHEBI:23026 alt_id: CHEBI:58657 def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a carboxylate" RELATED [UniProt] synonym: "carboxylic acid anions" RELATED [ChEBI] synonym: "carboxylic anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion relationship: is_conjugate_base_of CHEBI:33575 ! carboxylic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.00950" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:29101 name: sodium(1+) namespace: chebi_ontology alt_id: CHEBI:26717 alt_id: CHEBI:49766 alt_id: CHEBI:9175 def: "A monoatomic monocation obtained from sodium." [] subset: 3_STAR synonym: "Na(+)" RELATED [UniProt] synonym: "Na(+)" RELATED [IUPAC] synonym: "Na+" RELATED [KEGG_COMPOUND] synonym: "sodium cation" EXACT IUPAC_NAME [IUPAC] synonym: "SODIUM ION" RELATED [PDBeChem] synonym: "sodium(1+)" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(1+) ion" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(I) cation" EXACT IUPAC_NAME [IUPAC] xref: CAS:17341-25-2 {source="ChemIDplus"} xref: CAS:17341-25-2 {source="NIST Chemistry WebBook"} xref: Gmelin:15196 {source="Gmelin"} xref: KEGG:C01330 xref: PDBeChem:NA is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25414 ! monoatomic monocation is_a: CHEBI:33504 ! alkali metal cation is_a: CHEBI:37246 ! elemental sodium is_a: CHEBI:60242 ! monovalent inorganic cation relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FKNQFGJONOIPTF-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98922" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na+]" xsd:string [Term] id: CHEBI:29214 name: sulfonic acid namespace: chebi_ontology subset: 3_STAR synonym: "[SHO2(OH)]" RELATED [IUPAC] synonym: "acide sulfonique" RELATED [ChEBI] synonym: "HSHO3" RELATED [IUPAC] synonym: "hydridohydroxidodioxidosulfur" EXACT IUPAC_NAME [IUPAC] synonym: "sulfonic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Sulfonsaeure" RELATED [ChEBI] synonym: "sulphonic acid" RELATED [ChEBI] xref: Gmelin:1404640 {source="Gmelin"} is_a: CHEBI:33402 ! sulfur oxoacid relationship: is_conjugate_acid_of CHEBI:33543 ! sulfonate relationship: is_tautomer_of CHEBI:48854 ! sulfurous acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BDHFUVZGWQCTTF-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "82.08008" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "81.97247" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]S(O)(=O)=O" xsd:string [Term] id: CHEBI:29228 name: hydrogen fluoride namespace: chebi_ontology def: "A diatomic molecule containing covalently bonded hydrogen and fluorine atoms." [] subset: 3_STAR synonym: "[HF]" RELATED [IUPAC] synonym: "fluorane" EXACT IUPAC_NAME [IUPAC] synonym: "Fluoride" RELATED [KEGG_COMPOUND] synonym: "fluoridohydrogen" EXACT IUPAC_NAME [IUPAC] synonym: "fluorure d'hydrogene" RELATED [ChEBI] synonym: "Fluorwasserstoff" RELATED [ChEBI] synonym: "HF" RELATED [IUPAC] synonym: "hydrofluoric acid" RELATED [ChemIDplus] synonym: "Hydrogen fluoride" EXACT [KEGG_COMPOUND] synonym: "hydrogen fluoride" EXACT IUPAC_NAME [IUPAC] synonym: "Hydrogenfluorid" RELATED [ChEBI] xref: CAS:7664-39-3 {source="NIST Chemistry WebBook"} xref: CAS:7664-39-3 {source="ChemIDplus"} xref: CAS:7664-39-3 {source="KEGG COMPOUND"} xref: Drug_Central:4499 {source="DrugCentral"} xref: Gmelin:166 {source="Gmelin"} xref: KEGG:C16487 is_a: CHEBI:18140 ! hydrogen halide is_a: CHEBI:37176 ! mononuclear parent hydride relationship: is_conjugate_acid_of CHEBI:17051 ! fluoride relationship: is_conjugate_base_of CHEBI:50314 ! fluoronium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "FH" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/FH/h1H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KRHYYFGTRYWZRS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "20.00634" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "20.00623" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "F[H]" xsd:string [Term] id: CHEBI:29234 name: triton namespace: chebi_ontology def: "Nucleus of the (3)H atom." [] subset: 3_STAR synonym: "(3)1H(+)" RELATED [IUPAC] synonym: "(3)H(+)" RELATED [IUPAC] synonym: "t" RELATED [IUPAC] synonym: "T(+)" RELATED [IUPAC] synonym: "t(+)" RELATED [IUPAC] synonym: "tritium(1+)" EXACT IUPAC_NAME [IUPAC] synonym: "triton" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:90855 {source="Gmelin"} is_a: CHEBI:15378 ! hydron property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "T" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/p+1/i/hT" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "GPRLSGONYQIRFK-MNYXATJNSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "3.016" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3.01550" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[3H+]" xsd:string [Term] id: CHEBI:29238 name: tritium atom namespace: chebi_ontology def: "The radioactive isotope of hydrogen with relative atomic mass 3.016049 and half-life of 12.33 years (from Greek taurhoiotatauomicronsigma, third)." [] subset: 3_STAR synonym: "(3)1H" RELATED [IUPAC] synonym: "(3)H" RELATED [IUPAC] synonym: "hydrogen-3" RELATED [ChEBI] synonym: "T" RELATED [IUPAC] synonym: "tritio" RELATED [ChEBI] synonym: "tritium" EXACT IUPAC_NAME [IUPAC] synonym: "tritium" RELATED [ChEBI] synonym: "ueberschwerer Wasserstoff" RELATED [ChEBI] is_a: CHEBI:49637 ! hydrogen atom is_a: FBcv:0000511 ! 3H equivalent_to: FBcv:0000511 ! 3H relationship: has_part CHEBI:29234 ! triton property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "T" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2/h1H/i1+2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UFHFLCQGNIYNRP-NJFSPNSNSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "3.016" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3.01605" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[3H]" xsd:string [Term] id: CHEBI:29254 name: dihydrogenborate namespace: chebi_ontology subset: 3_STAR synonym: "[BO(OH)2](-)" RELATED [IUPAC] synonym: "dihydrogen(trioxidoborate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydrogenborate" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidooxidoborate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "H2BO3(-)" RELATED [IUPAC] xref: Gmelin:49252 {source="Gmelin"} is_a: CHEBI:22909 ! borate ion relationship: is_conjugate_acid_of CHEBI:29255 ! hydrogenborate relationship: is_conjugate_base_of CHEBI:33118 ! boric acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "BH2O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/BH2O3/c2-1(3)4/h2-3H/q-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "URSLCTBXQMKCFE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.82508" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "61.01025" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OB([O-])O[H]" xsd:string [Term] id: CHEBI:29255 name: hydrogenborate namespace: chebi_ontology subset: 3_STAR synonym: "[BO2(OH)](2-)" RELATED [IUPAC] synonym: "HBO3(2-)" RELATED [IUPAC] synonym: "hydrogen(trioxidoborate)(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogenborate" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidodioxidoborate(2-)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:674511 {source="Gmelin"} is_a: CHEBI:22909 ! borate ion relationship: is_conjugate_acid_of CHEBI:22908 ! borate relationship: is_conjugate_base_of CHEBI:29254 ! dihydrogenborate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "BHO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/BHO3/c2-1(3)4/h2H/q-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JSSGFLRDNVXLHY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "59.81714" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.00297" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OB([O-])[O-]" xsd:string [Term] id: CHEBI:29281 name: alkyl sulfate namespace: chebi_ontology alt_id: CHEBI:13810 alt_id: CHEBI:22325 alt_id: CHEBI:2583 subset: 3_STAR synonym: "alkyl sulfates" RELATED [ChEBI] is_a: CHEBI:25704 ! organic sulfate is_a: CHEBI:26819 ! sulfuric ester relationship: is_conjugate_acid_of CHEBI:83414 ! alkyl sulfate(1-) [Term] id: CHEBI:29337 name: azanide namespace: chebi_ontology subset: 3_STAR synonym: "amide" EXACT IUPAC_NAME [IUPAC] synonym: "azanide" EXACT IUPAC_NAME [IUPAC] synonym: "dihydridonitrate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "NH2(-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:29340 ! hydridonitrate(2-) relationship: is_conjugate_base_of CHEBI:16134 ! ammonia property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2N/h1H2/q-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "HYGWNUKOUCZBND-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "16.02262" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "16.01927" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N-][H]" xsd:string [Term] id: CHEBI:29340 name: hydridonitrate(2-) namespace: chebi_ontology def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." [] subset: 3_STAR synonym: "azanediide" EXACT IUPAC_NAME [IUPAC] synonym: "hydridonitrate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "imide" RELATED [IUPAC] synonym: "NH(2-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:29337 ! azanide property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HN" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/HN/h1H/q-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DZQYTNGKSBCIOE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.01468" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.01200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[N--][H]" xsd:string [Term] id: CHEBI:29347 name: monocarboxylic acid amide namespace: chebi_ontology alt_id: CHEBI:13211 alt_id: CHEBI:22207 alt_id: CHEBI:25383 alt_id: CHEBI:6977 def: "A carboxamide derived from a monocarboxylic acid." [] subset: 3_STAR synonym: "monocarboxylic acid amides" RELATED [ChEBI] is_a: CHEBI:37622 ! carboxamide property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CNOR3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "42.01680" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "41.99799" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]N([*])C([*])=O" xsd:string [Term] id: CHEBI:29785 name: nitro group namespace: chebi_ontology subset: 3_STAR synonym: "-NO2" RELATED [IUPAC] synonym: "nitro" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33246 ! inorganic group is_a: CHEBI:51144 ! nitrogen group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "46.00550" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "45.99290" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*[N+](=O)[O-]" xsd:string [Term] id: CHEBI:29865 name: benzo[a]pyrene namespace: chebi_ontology alt_id: CHEBI:22716 alt_id: CHEBI:3045 def: "An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings." [] subset: 3_STAR synonym: "(B(a)P)" RELATED [ChEBI] synonym: "3,4-Benzopyrene" RELATED [NIST_Chemistry_WebBook] synonym: "3,4-Benzpyrene" RELATED [NIST_Chemistry_WebBook] synonym: "3,4-BP" RELATED [NIST_Chemistry_WebBook] synonym: "Benzo(a)pyrene" RELATED [ChemIDplus] synonym: "Benzo[a]pyrene" EXACT [KEGG_COMPOUND] synonym: "benzo[def]chrysene" RELATED [ChEBI] synonym: "benzo[pqr]tetraphene" EXACT IUPAC_NAME [IUPAC] synonym: "Benzpyrene" RELATED [KEGG_COMPOUND] synonym: "BP" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1911333 {source="Beilstein"} xref: CAS:50-32-8 {source="ChemIDplus"} xref: CAS:50-32-8 {source="NIST Chemistry WebBook"} xref: CAS:50-32-8 {source="KEGG COMPOUND"} xref: Gmelin:262573 {source="Gmelin"} xref: KEGG:C07535 xref: LINCS:LSM-2198 xref: PMID:11932001 {source="Europe PMC"} xref: PMID:16256111 {source="Europe PMC"} xref: PMID:16381670 {source="Europe PMC"} xref: PMID:1844333 {source="Europe PMC"} xref: PMID:26530167 {source="Europe PMC"} xref: PMID:26703252 {source="Europe PMC"} xref: PMID:7561049 {source="Europe PMC"} xref: PMID:7721048 {source="Europe PMC"} xref: Reaxys:1911333 {source="Reaxys"} xref: Wikipedia:Benzo(a)pyrene is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene is_a: FBcv:0000574 ! benzo(alpha)pyrene equivalent_to: FBcv:0000574 ! benzo(alpha)pyrene relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:75771 ! mouse metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C20H12" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C20H12/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h1-12H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FMMWHPNWAFZXNH-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "252.30928" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "252.09390" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34" xsd:string [Term] id: CHEBI:29922 name: sulfo group namespace: chebi_ontology subset: 3_STAR synonym: "-S(O)2(OH)" RELATED [IUPAC] synonym: "hydroxydioxo-lambda(6)-sulfanyl" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxysulfonyl" EXACT IUPAC_NAME [IUPAC] synonym: "sulfo" EXACT IUPAC_NAME [IUPAC] synonym: "SULFO GROUP" EXACT [PDBeChem] xref: PDBeChem:SFO is_a: CHEBI:33246 ! inorganic group relationship: is_substituent_group_from CHEBI:29214 ! sulfonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "81.07214" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "80.96464" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "S(=O)(O)(*)=O" xsd:string [Term] id: CHEBI:29985 name: L-glutamate(1-) namespace: chebi_ontology alt_id: CHEBI:13107 alt_id: CHEBI:21301 def: "An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group" [] subset: 3_STAR synonym: "(2S)-2-ammoniopentanedioate" RELATED [IUPAC] synonym: "hydrogen L-glutamate" EXACT IUPAC_NAME [IUPAC] synonym: "L-glutamate" RELATED [ChEBI] synonym: "L-glutamate" RELATED [UniProt] synonym: "L-glutamate(1-)" EXACT [JCBN] synonym: "L-glutamic acid monoanion" RELATED [JCBN] synonym: "L-glutamic acid, ion(1-)" RELATED [ChemIDplus] xref: CAS:11070-68-1 {source="ChemIDplus"} xref: Gmelin:936654 {source="Gmelin"} xref: MetaCyc:GLT is_a: CHEBI:14321 ! glutamate(1-) is_a: CHEBI:62031 ! polar amino acid zwitterion is_a: FBcv:0000551 ! enzyme inhibitor relationship: has_role CHEBI:24319 ! EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:29988 ! L-glutamate(2-) relationship: is_conjugate_base_of CHEBI:16015 ! L-glutamic acid relationship: is_enantiomer_of CHEBI:29986 ! D-glutamate(1-) property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H8NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-VKHMYHEASA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "146.12136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.04588" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@@H](CCC([O-])=O)C([O-])=O" xsd:string [Term] id: CHEBI:29986 name: D-glutamate(1-) namespace: chebi_ontology alt_id: CHEBI:12979 alt_id: CHEBI:21022 def: "An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group" [] subset: 3_STAR synonym: "(2R)-2-ammoniopentanedioate" RELATED [IUPAC] synonym: "D-glutamate" RELATED [UniProt] synonym: "D-glutamate(1-)" EXACT [JCBN] synonym: "D-glutamic acid monoanion" RELATED [JCBN] synonym: "hydrogen D-glutamate" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:8319427 {source="Beilstein"} xref: MetaCyc:D-GLT is_a: CHEBI:14321 ! glutamate(1-) relationship: is_conjugate_acid_of CHEBI:29989 ! D-glutamate(2-) relationship: is_conjugate_base_of CHEBI:15966 ! D-glutamic acid relationship: is_enantiomer_of CHEBI:29985 ! L-glutamate(1-) property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H8NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-GSVOUGTGSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "146.12136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.04588" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@H](CCC([O-])=O)C([O-])=O" xsd:string [Term] id: CHEBI:29987 name: glutamate(2-) namespace: chebi_ontology def: "A dicarboxylic acid dianion that is the conjugate base of glutamate(1-)." [] subset: 3_STAR synonym: "2-aminopentanedioate" EXACT IUPAC_NAME [IUPAC] synonym: "glutamate" EXACT IUPAC_NAME [IUPAC] synonym: "glutamate(2-)" EXACT [JCBN] synonym: "glutamic acid dianion" RELATED [JCBN] xref: Beilstein:4134100 {source="Beilstein"} xref: Gmelin:327903 {source="Gmelin"} xref: Reaxys:4134100 {source="Reaxys"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:28965 ! dicarboxylic acid dianion relationship: has_role CHEBI:78675 ! fundamental metabolite relationship: is_conjugate_base_of CHEBI:14321 ! glutamate(1-) property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H7NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "145.11342" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "145.03860" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(CCC([O-])=O)C([O-])=O" xsd:string [Term] id: CHEBI:29988 name: L-glutamate(2-) namespace: chebi_ontology def: "An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid." [] subset: 3_STAR synonym: "(2S)-2-aminopentanedioate" EXACT IUPAC_NAME [IUPAC] synonym: "L-glutamate" EXACT IUPAC_NAME [IUPAC] synonym: "L-glutamate(2-)" EXACT [JCBN] synonym: "L-glutamic acid dianion" RELATED [JCBN] xref: Gmelin:327905 {source="Gmelin"} is_a: CHEBI:29987 ! glutamate(2-) is_a: CHEBI:59814 ! L-alpha-amino acid anion relationship: is_conjugate_base_of CHEBI:29985 ! L-glutamate(1-) relationship: is_enantiomer_of CHEBI:29989 ! D-glutamate(2-) property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H7NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-VKHMYHEASA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "145.11342" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "145.03860" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@@H](CCC([O-])=O)C([O-])=O" xsd:string [Term] id: CHEBI:29989 name: D-glutamate(2-) namespace: chebi_ontology subset: 3_STAR synonym: "(2R)-2-aminopentanedioate" EXACT IUPAC_NAME [IUPAC] synonym: "D-glutamate" EXACT IUPAC_NAME [IUPAC] synonym: "D-glutamate(2-)" EXACT [JCBN] synonym: "D-glutamic acid dianion" RELATED [JCBN] xref: Beilstein:8143000 {source="Beilstein"} xref: Gmelin:327904 {source="Gmelin"} is_a: CHEBI:29987 ! glutamate(2-) relationship: is_conjugate_base_of CHEBI:29986 ! D-glutamate(1-) relationship: is_enantiomer_of CHEBI:29988 ! L-glutamate(2-) property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H7NO4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WHUUTDBJXJRKMK-GSVOUGTGSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "145.11342" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "145.03860" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@H](CCC([O-])=O)C([O-])=O" xsd:string [Term] id: CHEBI:30087 name: guanidinium namespace: chebi_ontology subset: 3_STAR synonym: "[C(NH2)3](+)" RELATED [ChEBI] synonym: "diaminomethaniminium" RELATED [IUPAC] synonym: "guanidine" RELATED [UniProt] synonym: "guanidinium" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:1902006 {source="Beilstein"} xref: Gmelin:239627 {source="Gmelin"} is_a: CHEBI:60251 ! guanidinium ion relationship: is_conjugate_acid_of CHEBI:42820 ! guanidine relationship: is_conjugate_acid_of CHEBI:616459 ! carbamimidoylazanium property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH6N3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ZRALSGWEFCBTJO-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.07856" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.05562" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(N)=[NH2+]" xsd:string [Term] id: CHEBI:30412 name: monoatomic dication namespace: chebi_ontology alt_id: CHEBI:23856 alt_id: CHEBI:4665 subset: 3_STAR synonym: "Divalent cation" RELATED [KEGG_COMPOUND] synonym: "divalent inorganic cations" RELATED [ChEBI] synonym: "monoatomic dications" RELATED [ChEBI] xref: KEGG:C00572 is_a: CHEBI:23906 ! monoatomic cation property_value: http://purl.obolibrary.org/obo/chebi/charge "+2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*++]" xsd:string [Term] id: CHEBI:30751 name: formic acid namespace: chebi_ontology alt_id: CHEBI:24082 alt_id: CHEBI:42460 alt_id: CHEBI:5145 def: "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." [] subset: 3_STAR synonym: "Acide formique" RELATED [ChemIDplus] synonym: "Ameisensaeure" RELATED [ChemIDplus] synonym: "aminic acid" RELATED [ChemIDplus] synonym: "bilorin" RELATED [ChemIDplus] synonym: "FORMIC ACID" EXACT [PDBeChem] synonym: "Formic acid" EXACT [KEGG_COMPOUND] synonym: "formic acid" EXACT IUPAC_NAME [IUPAC] synonym: "formylic acid" RELATED [ChemIDplus] synonym: "H-COOH" RELATED [IUPAC] synonym: "HCO2H" RELATED [ChEBI] synonym: "HCOOH" RELATED [NIST_Chemistry_WebBook] synonym: "hydrogen carboxylic acid" RELATED [ChemIDplus] synonym: "Methanoic acid" RELATED [KEGG_COMPOUND] synonym: "methoic acid" RELATED [ChEBI] xref: Beilstein:1209246 {source="Beilstein"} xref: BPDB:1749 xref: CAS:64-18-6 {source="NIST Chemistry WebBook"} xref: CAS:64-18-6 {source="ChemIDplus"} xref: CAS:64-18-6 {source="KEGG COMPOUND"} xref: DrugBank:DB01942 xref: Gmelin:1008 {source="Gmelin"} xref: HMDB:HMDB0000142 xref: KEGG:C00058 xref: KNApSAcK:C00001182 xref: LIPID_MAPS_instance:LMFA01010040 {source="LIPID MAPS"} xref: MetaCyc:FORMATE xref: Patent:CN101481304 xref: PDBeChem:FMT xref: PMID:12591956 {source="Europe PMC"} xref: PMID:14637377 {source="Europe PMC"} xref: PMID:15811469 {source="Europe PMC"} xref: PMID:16120414 {source="Europe PMC"} xref: PMID:16185830 {source="Europe PMC"} xref: PMID:16222862 {source="Europe PMC"} xref: PMID:16230297 {source="Europe PMC"} xref: PMID:16445901 {source="Europe PMC"} xref: PMID:16465784 {source="Europe PMC"} xref: PMID:18034701 {source="Europe PMC"} xref: PMID:18397576 {source="Europe PMC"} xref: PMID:22080171 {source="Europe PMC"} xref: PMID:22280475 {source="Europe PMC"} xref: PMID:22304812 {source="Europe PMC"} xref: PMID:22385261 {source="Europe PMC"} xref: PMID:22447125 {source="Europe PMC"} xref: PMID:22483350 {source="Europe PMC"} xref: PMID:22499553 {source="Europe PMC"} xref: PMID:22540994 {source="Europe PMC"} xref: PMID:22606986 {source="Europe PMC"} xref: PMID:22622393 {source="Europe PMC"} xref: PMID:3946945 {source="Europe PMC"} xref: PMID:7361809 {source="Europe PMC"} xref: Reaxys:1209246 {source="Reaxys"} xref: Wikipedia:Formic_acid is_a: CHEBI:25384 ! monocarboxylic acid relationship: has_role CHEBI:25212 ! metabolite relationship: has_role CHEBI:33282 ! antibacterial agent relationship: has_role CHEBI:46787 ! solvent relationship: has_role CHEBI:48356 ! protic solvent relationship: has_role CHEBI:74783 ! astringent relationship: is_conjugate_acid_of CHEBI:15740 ! formate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "46.02538" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "46.00548" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C(O)=O" xsd:string [Term] id: CHEBI:30879 name: alcohol namespace: chebi_ontology alt_id: CHEBI:13804 alt_id: CHEBI:22288 alt_id: CHEBI:2553 def: "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom." [] subset: 3_STAR synonym: "Alcohol" EXACT [KEGG_COMPOUND] synonym: "alcohols" EXACT IUPAC_NAME [IUPAC] synonym: "an alcohol" RELATED [UniProt] xref: KEGG:C00069 is_a: CHEBI:33822 ! organic hydroxy compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HOR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.007" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O[*]" xsd:string [Term] id: CHEBI:30969 name: aziridine namespace: chebi_ontology alt_id: CHEBI:24004 alt_id: CHEBI:2954 subset: 3_STAR synonym: "azacyclopropane" RELATED [NIST_Chemistry_WebBook] synonym: "Aziridine" EXACT [KEGG_COMPOUND] synonym: "aziridine" EXACT IUPAC_NAME [IUPAC] synonym: "dimethyleneimine" RELATED [NIST_Chemistry_WebBook] synonym: "EI" RELATED [NIST_Chemistry_WebBook] synonym: "ethyleneimine" RELATED [ChemIDplus] synonym: "ethylenimine" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:102380 {source="Beilstein"} xref: CAS:151-56-4 {source="NIST Chemistry WebBook"} xref: CAS:151-56-4 {source="KEGG COMPOUND"} xref: CAS:151-56-4 {source="ChemIDplus"} xref: Gmelin:616 {source="Gmelin"} xref: KEGG:C11687 is_a: CHEBI:22681 ! aziridines is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent is_a: CHEBI:37949 ! azacycloalkane is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000581 ! ethylenimine equivalent_to: FBcv:0000581 ! ethylenimine relationship: has_role CHEBI:22333 ! alkylating agent relationship: is_conjugate_base_of CHEBI:50929 ! aziridinium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H5N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NOWKCMXCCJGMRR-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "43.06784" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.04220" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1CN1" xsd:string [Term] id: CHEBI:31011 name: valerate namespace: chebi_ontology alt_id: CHEBI:14751 alt_id: CHEBI:25890 def: "A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals." [] subset: 3_STAR synonym: "CH3-[CH2]3-COO(-)" RELATED [IUPAC] synonym: "n-propylacetate" RELATED [ChEBI] synonym: "pentanoate" EXACT IUPAC_NAME [IUPAC] synonym: "pentanoate" RELATED [UniProt] synonym: "pentanoic acid, ion(1-)" RELATED [ChemIDplus] xref: Beilstein:3903735 {source="Beilstein"} xref: CAS:10023-74-2 {source="ChemIDplus"} xref: Gmelin:325619 {source="Gmelin"} xref: PMID:17314444 {source="Europe PMC"} xref: PMID:18783570 {source="Europe PMC"} xref: Reaxys:3903735 {source="Reaxys"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:58951 ! short-chain fatty acid anion is_a: CHEBI:58954 ! straight-chain saturated fatty acid anion relationship: has_role CHEBI:76924 ! plant metabolite relationship: is_conjugate_base_of CHEBI:17418 ! valeric acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H9O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NQPDZGIKBAWPEJ-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "101.12376" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "101.06080" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCCCC([O-])=O" xsd:string [Term] id: CHEBI:32456 name: cysteinate(1-) namespace: chebi_ontology def: "A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group." [] subset: 3_STAR synonym: "2-amino-3-mercaptopropanoate" RELATED [ChEBI] synonym: "2-amino-3-sulfanylpropanoate" RELATED [IUPAC] synonym: "cys(-)" RELATED [IUPAC] synonym: "cysteinate(1-)" EXACT [JCBN] synonym: "cysteine monoanion" RELATED [JCBN] synonym: "hydrogen cysteinate" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:4128885 {source="Beilstein"} xref: Gmelin:363235 {source="Gmelin"} xref: Reaxys:4128885 {source="Reaxys"} is_a: CHEBI:33558 ! alpha-amino-acid anion is_a: CHEBI:63470 ! sulfur-containing amino-acid anion relationship: is_conjugate_acid_of CHEBI:32457 ! cysteinate(2-) relationship: is_conjugate_base_of CHEBI:15356 ! cysteine relationship: is_conjugate_base_of CHEBI:35237 ! cysteine zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H6NO2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "120.15128" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "120.01247" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(CS)C([O-])=O" xsd:string [Term] id: CHEBI:32457 name: cysteinate(2-) namespace: chebi_ontology subset: 3_STAR synonym: "2-amino-3-sulfidopropanoate" RELATED [IUPAC] synonym: "cysteinate" EXACT IUPAC_NAME [IUPAC] synonym: "cysteinate(2-)" EXACT [JCBN] synonym: "cysteine dianion" RELATED [JCBN] xref: Gmelin:49990 {source="Gmelin"} is_a: CHEBI:33558 ! alpha-amino-acid anion relationship: is_conjugate_base_of CHEBI:32456 ! cysteinate(1-) property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H5NO2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "119.14334" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "119.00520" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(C[S-])C([O-])=O" xsd:string [Term] id: CHEBI:32458 name: cysteinium namespace: chebi_ontology subset: 3_STAR synonym: "1-carboxy-2-mercaptoethanaminium" RELATED [ChEBI] synonym: "1-carboxy-2-sulfanylethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "cysteine cation" RELATED [JCBN] synonym: "cysteinium" EXACT [JCBN] synonym: "H2cys(+)" RELATED [IUPAC] xref: Gmelin:325859 {source="Gmelin"} is_a: CHEBI:33719 ! alpha-amino-acid cation relationship: is_conjugate_acid_of CHEBI:15356 ! cysteine relationship: is_conjugate_acid_of CHEBI:35237 ! cysteine zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H8NO2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "122.16716" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "122.02703" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C(CS)C(O)=O" xsd:string [Term] id: CHEBI:32486 name: L-phenylalaninate namespace: chebi_ontology def: "An optically active form of phenylalaninate having L-configuration." [] subset: 3_STAR synonym: "(2S)-2-amino-3-phenylpropanoate" RELATED [IUPAC] synonym: "L-phenylalaninate" EXACT IUPAC_NAME [IUPAC] synonym: "L-phenylalanine anion" RELATED [JCBN] xref: Beilstein:4136718 {source="Beilstein"} xref: Gmelin:329084 {source="Gmelin"} xref: PMID:21956539 {source="Europe PMC"} xref: Reaxys:4136718 {source="Reaxys"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:32504 ! phenylalaninate is_a: CHEBI:59814 ! L-alpha-amino acid anion relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_base_of CHEBI:17295 ! L-phenylalanine relationship: is_enantiomer_of CHEBI:32494 ! D-phenylalaninate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H10NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-QMMMGPOBSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "164.18120" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "164.07170" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@@H](Cc1ccccc1)C([O-])=O" xsd:string [Term] id: CHEBI:32487 name: L-phenylalaninium namespace: chebi_ontology def: "An optically active form of phenylalaninium having L-configuration." [] subset: 3_STAR synonym: "(1S)-1-carboxy-2-phenylethanaminium" RELATED [IUPAC] synonym: "L-phenylalanine cation" RELATED [JCBN] synonym: "L-phenylalaninium" EXACT IUPAC_NAME [IUPAC] xref: PMID:21956539 {source="Europe PMC"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:32505 ! phenylalaninium relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_acid_of CHEBI:17295 ! L-phenylalanine relationship: is_enantiomer_of CHEBI:32495 ! D-phenylalaninium property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H12NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-QMMMGPOBSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "166.19710" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "166.08626" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@@H](Cc1ccccc1)C(O)=O" xsd:string [Term] id: CHEBI:32494 name: D-phenylalaninate namespace: chebi_ontology def: "The D-enantiomer of phenylalaninate." [] subset: 3_STAR synonym: "(2R)-2-amino-3-phenylpropanoate" RELATED [IUPAC] synonym: "D-phenylalaninate" EXACT IUPAC_NAME [IUPAC] synonym: "D-phenylalanine anion" RELATED [JCBN] xref: Beilstein:5740552 {source="Beilstein"} xref: Gmelin:746993 {source="Gmelin"} is_a: CHEBI:32504 ! phenylalaninate relationship: is_conjugate_base_of CHEBI:16998 ! D-phenylalanine relationship: is_enantiomer_of CHEBI:32486 ! L-phenylalaninate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H10NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1/t8-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-MRVPVSSYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "164.18120" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "164.07170" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "N[C@H](Cc1ccccc1)C([O-])=O" xsd:string [Term] id: CHEBI:32495 name: D-phenylalaninium namespace: chebi_ontology def: "An optically active form of phenylalaninium having D-configuration." [] subset: 3_STAR synonym: "(1R)-1-carboxy-2-phenylethanaminium" RELATED [IUPAC] synonym: "D-phenylalanine cation" RELATED [JCBN] synonym: "D-phenylalaninium" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:32505 ! phenylalaninium relationship: is_conjugate_acid_of CHEBI:16998 ! D-phenylalanine relationship: is_enantiomer_of CHEBI:32487 ! L-phenylalaninium property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H12NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1/t8-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-MRVPVSSYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "166.19710" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "166.08626" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@H](Cc1ccccc1)C(O)=O" xsd:string [Term] id: CHEBI:32504 name: phenylalaninate namespace: chebi_ontology def: "An aromatic amino-acid anion that is the conjugate base of phenylalanine, arising from deprotonation of the carboxy group." [] subset: 3_STAR synonym: "2-amino-3-phenylpropanoate" RELATED [IUPAC] synonym: "phenylalaninate" EXACT IUPAC_NAME [IUPAC] synonym: "phenylalanine anion" RELATED [JCBN] xref: Gmelin:329083 {source="Gmelin"} is_a: CHEBI:33558 ! alpha-amino-acid anion is_a: CHEBI:63473 ! aromatic amino-acid anion relationship: is_conjugate_base_of CHEBI:28044 ! phenylalanine property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H10NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "164.18120" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "164.07170" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(Cc1ccccc1)C([O-])=O" xsd:string [Term] id: CHEBI:32505 name: phenylalaninium namespace: chebi_ontology def: "An alpha-amino-acid cation that is the conjugate acid of phenylalanine, arising from protonation of the amino group." [] subset: 3_STAR synonym: "1-carboxy-2-phenylethanaminium" RELATED [IUPAC] synonym: "phenylalanine cation" RELATED [JCBN] synonym: "phenylalaninium" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33719 ! alpha-amino-acid cation relationship: is_conjugate_acid_of CHEBI:28044 ! phenylalanine property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H12NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "166.19710" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "166.08626" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C(Cc1ccccc1)C(O)=O" xsd:string [Term] id: CHEBI:32955 name: epoxide namespace: chebi_ontology alt_id: CHEBI:13828 alt_id: CHEBI:23930 alt_id: CHEBI:4812 def: "Any cyclic ether in which the oxygen atom forms part of a 3-membered ring." [] subset: 3_STAR synonym: "Alkene oxide" RELATED [KEGG_COMPOUND] synonym: "an epoxide" RELATED [UniProt] synonym: "Epoxide" EXACT [KEGG_COMPOUND] synonym: "epoxides" EXACT IUPAC_NAME [IUPAC] synonym: "epoxides" RELATED [ChEBI] synonym: "Olefin oxide" RELATED [KEGG_COMPOUND] xref: KEGG:C00722 xref: PMID:10891060 {source="Europe PMC"} xref: Wikipedia:Epoxide is_a: CHEBI:37407 ! cyclic ether relationship: has_parent_hydride CHEBI:27561 ! oxirane property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2OR4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "40.02080" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "39.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C1([*])OC1([*])[*]" xsd:string [Term] id: CHEBI:32988 name: amide namespace: chebi_ontology alt_id: CHEBI:22473 alt_id: CHEBI:2633 def: "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "Amide" EXACT [KEGG_COMPOUND] synonym: "amides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00241 is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:33118 name: boric acid namespace: chebi_ontology alt_id: CHEBI:22911 alt_id: CHEBI:31299 alt_id: CHEBI:41248 subset: 3_STAR synonym: "[B(OH)3]" RELATED [MolBase] synonym: "B(OH)3" RELATED [NIST_Chemistry_WebBook] synonym: "BORIC ACID" EXACT [PDBeChem] synonym: "Boric acid" EXACT [KEGG_COMPOUND] synonym: "boric acid" EXACT [IUPAC] synonym: "boron trihydroxide" RELATED [NIST_Chemistry_WebBook] synonym: "H3BO3" RELATED [IUPAC] synonym: "orthoboric acid" RELATED [NIST_Chemistry_WebBook] synonym: "trihydroxidoboron" EXACT IUPAC_NAME [IUPAC] xref: BPDB:2136 xref: CAS:10043-35-3 {source="NIST Chemistry WebBook"} xref: CAS:10043-35-3 {source="ChemIDplus"} xref: CAS:10043-35-3 {source="KEGG COMPOUND"} xref: CAS:11113-50-1 {source="ChemIDplus"} xref: Drug_Central:3035 {source="DrugCentral"} xref: Gmelin:1585 {source="Gmelin"} xref: KEGG:C12486 xref: KEGG:D01089 xref: MolBase:1644 xref: PDBeChem:BO3 xref: PPDB:2136 is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:59765 ! boric acids is_a: FBcv:0000553 ! inorganic compound is_a: FBcv:0000555 ! H3BO3 equivalent_to: FBcv:0000555 ! H3BO3 relationship: has_role CHEBI:74783 ! astringent relationship: is_conjugate_acid_of CHEBI:29254 ! dihydrogenborate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "BH3O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/BH3O3/c2-1(3)4/h2-4H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KGBXLFKZBHKPEV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "61.83302" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.01752" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OB(O[H])O[H]" xsd:string [Term] id: CHEBI:33145 name: boron oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "boron oxoacid" EXACT [ChEBI] synonym: "boron oxoacids" RELATED [ChEBI] synonym: "oxoacids of boron" RELATED [ChEBI] is_a: CHEBI:22916 ! boron molecular entity is_a: CHEBI:24833 ! oxoacid [Term] id: CHEBI:33229 name: vitamin (role) namespace: chebi_ontology alt_id: CHEBI:10004 alt_id: CHEBI:27305 def: "A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term \"vitamines\" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines." [] subset: 3_STAR synonym: "vitamin" RELATED [ChEBI] synonym: "vitamina" RELATED [ChEBI] synonym: "vitaminas" RELATED [ChEBI] synonym: "vitamine" RELATED [ChEBI] synonym: "vitamines" RELATED [ChEBI] synonym: "vitamins" RELATED [ChEBI] synonym: "vitaminum" RELATED [ChEBI] xref: Wikipedia:Vitamin is_a: CHEBI:27027 ! micronutrient is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:33232 name: application namespace: chebi_ontology def: "Intended use of the molecular entity or part thereof by humans." [] subset: 3_STAR is_a: CHEBI:50906 ! role [Term] id: CHEBI:33233 name: fundamental particle namespace: chebi_ontology def: "A particle not known to have substructure." [] subset: 3_STAR synonym: "elementary particle" EXACT IUPAC_NAME [IUPAC] synonym: "elementary particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:33238 name: monoatomic entity namespace: chebi_ontology def: "A monoatomic entity is a molecular entity consisting of a single atom." [] subset: 3_STAR synonym: "atomic entity" RELATED [ChEBI] synonym: "monoatomic entities" RELATED [ChEBI] is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33240 name: coordination entity namespace: chebi_ontology def: "An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands)." [] subset: 3_STAR synonym: "coordination compounds" RELATED [ChEBI] synonym: "coordination entities" EXACT IUPAC_NAME [IUPAC] synonym: "coordination entity" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:33241 name: oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_functional_parent CHEBI:24833 ! oxoacid [Term] id: CHEBI:33242 name: inorganic hydride namespace: chebi_ontology subset: 3_STAR synonym: "inorganic hydrides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:33692 ! hydrides is_a: FBcv:0000553 ! inorganic compound [Term] id: CHEBI:33245 name: organic fundamental parent namespace: chebi_ontology def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." [] subset: 3_STAR synonym: "organic fundamental parents" RELATED [ChEBI] synonym: "organic parent hydrides" RELATED [ChEBI] is_a: CHEBI:37175 ! organic hydride is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33246 name: inorganic group namespace: chebi_ontology def: "Any substituent group which does not contain carbon." [] subset: 3_STAR synonym: "inorganic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group [Term] id: CHEBI:33247 name: organic group namespace: chebi_ontology def: "Any substituent group or skeleton containing carbon." [] subset: 3_STAR synonym: "organic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group relationship: is_substituent_group_from CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33248 name: hydrocarbyl group namespace: chebi_ontology def: "A univalent group formed by removing a hydrogen atom from a hydrocarbon." [] subset: 3_STAR synonym: "groupe hydrocarbyle" RELATED [IUPAC] synonym: "grupo hidrocarbilo" RELATED [IUPAC] synonym: "grupos hidrocarbilo" RELATED [IUPAC] synonym: "hydrocarbyl group" EXACT [IUPAC] synonym: "hydrocarbyl groups" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33249 ! organyl group relationship: is_substituent_group_from CHEBI:24632 ! hydrocarbon [Term] id: CHEBI:33249 name: organyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." [] subset: 3_STAR synonym: "groupe organyle" RELATED [IUPAC] synonym: "grupo organilo" RELATED [IUPAC] synonym: "grupos organilo" RELATED [IUPAC] synonym: "organyl group" EXACT IUPAC_NAME [IUPAC] synonym: "organyl groups" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51447 ! organic univalent group [Term] id: CHEBI:33250 name: atom namespace: chebi_ontology alt_id: CHEBI:22671 alt_id: CHEBI:23907 def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." [] subset: 3_STAR synonym: "atom" EXACT IUPAC_NAME [IUPAC] synonym: "atome" RELATED [IUPAC] synonym: "atomo" RELATED [IUPAC] synonym: "atoms" RELATED [ChEBI] synonym: "atomus" RELATED [ChEBI] synonym: "element" RELATED [ChEBI] synonym: "elements" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical relationship: has_part CHEBI:10545 ! electron relationship: has_part CHEBI:33252 ! atomic nucleus [Term] id: CHEBI:33251 name: monoatomic hydrogen namespace: chebi_ontology subset: 3_STAR synonym: "atomic hydrogen" RELATED [ChEBI] is_a: CHEBI:33238 ! monoatomic entity is_a: CHEBI:33260 ! elemental hydrogen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1.00794" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.00783" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]" xsd:string [Term] id: CHEBI:33252 name: atomic nucleus namespace: chebi_ontology def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." [] subset: 3_STAR synonym: "Atomkern" RELATED [ChEBI] synonym: "Kern" RELATED [ChEBI] synonym: "noyau" RELATED [IUPAC] synonym: "noyau atomique" RELATED [ChEBI] synonym: "nuclei" RELATED [ChEBI] synonym: "nucleo" RELATED [IUPAC] synonym: "nucleo atomico" RELATED [ChEBI] synonym: "nucleus" EXACT IUPAC_NAME [IUPAC] synonym: "nucleus atomi" RELATED [ChEBI] is_a: CHEBI:36347 ! nuclear particle relationship: has_part CHEBI:33253 ! nucleon [Term] id: CHEBI:33253 name: nucleon namespace: chebi_ontology def: "Heavy nuclear particle: proton or neutron." [] subset: 3_STAR synonym: "nucleon" EXACT [IUPAC] synonym: "nucleon" EXACT IUPAC_NAME [IUPAC] synonym: "nucleons" RELATED [ChEBI] synonym: "Nukleon" RELATED [ChEBI] synonym: "Nukleonen" RELATED [ChEBI] is_a: CHEBI:36339 ! baryon is_a: CHEBI:36347 ! nuclear particle [Term] id: CHEBI:33256 name: primary amide namespace: chebi_ontology def: "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "primary amide" EXACT [IUPAC] synonym: "primary amides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:32988 ! amide [Term] id: CHEBI:33259 name: elemental molecular entity namespace: chebi_ontology def: "A molecular entity all atoms of which have the same atomic number." [] subset: 3_STAR synonym: "homoatomic entity" RELATED [ChEBI] synonym: "homoatomic molecular entities" RELATED [ChEBI] synonym: "homoatomic molecular entity" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:33260 name: elemental hydrogen namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:33259 ! elemental molecular entity is_a: CHEBI:33608 ! hydrogen molecular entity is_a: FBcv:0000553 ! inorganic compound [Term] id: CHEBI:33261 name: organosulfur compound namespace: chebi_ontology alt_id: CHEBI:23010 alt_id: CHEBI:25714 def: "An organosulfur compound is a compound containing at least one carbon-sulfur bond." [] subset: 3_STAR synonym: "organosulfur compound" EXACT [ChEBI] synonym: "organosulfur compounds" RELATED [ChEBI] xref: Wikipedia:Organosulfur_compounds is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:33273 name: polyatomic anion namespace: chebi_ontology def: "An anion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36358 ! polyatomic ion [Term] id: CHEBI:33280 name: molecular messenger namespace: chebi_ontology subset: 3_STAR synonym: "chemical messenger" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33281 name: antimicrobial agent namespace: chebi_ontology alt_id: CHEBI:22582 def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." [] subset: 3_STAR synonym: "antibiotic" RELATED [ChEBI] synonym: "antibiotics" RELATED [ChEBI] synonym: "Antibiotika" RELATED [ChEBI] synonym: "Antibiotikum" RELATED [ChEBI] synonym: "antibiotique" RELATED [IUPAC] synonym: "antimicrobial" RELATED [ChEBI] synonym: "antimicrobial agents" RELATED [ChEBI] synonym: "antimicrobials" RELATED [ChEBI] synonym: "microbicide" RELATED [ChEBI] synonym: "microbicides" RELATED [ChEBI] xref: PMID:12964249 {source="Europe PMC"} xref: PMID:22117953 {source="Europe PMC"} xref: PMID:22439833 {source="Europe PMC"} xref: PMID:22849268 {source="Europe PMC"} xref: PMID:22849276 {source="Europe PMC"} xref: PMID:22958833 {source="Europe PMC"} is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33282 name: antibacterial agent namespace: chebi_ontology def: "A substance (or active part thereof) that kills or slows the growth of bacteria." [] subset: 3_STAR synonym: "antibacterial agents" RELATED [ChEBI] synonym: "antibacterials" RELATED [ChEBI] synonym: "bactericide" RELATED [ChEBI] synonym: "bactericides" RELATED [ChEBI] is_a: CHEBI:33281 ! antimicrobial agent [Term] id: CHEBI:33284 name: nutrient namespace: chebi_ontology def: "A nutrient is a food component that an organism uses to survive and grow." [] subset: 3_STAR synonym: "nutrients" RELATED [ChEBI] is_a: CHEBI:78295 ! food component [Term] id: CHEBI:33285 name: heteroorganic entity namespace: chebi_ontology def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." [] subset: 3_STAR synonym: "heteroorganic entities" RELATED [ChEBI] synonym: "organoelement compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33286 name: agrochemical namespace: chebi_ontology def: "An agrochemical is a substance that is used in agriculture or horticulture." [] subset: 3_STAR synonym: "agrichemical" RELATED [ChEBI] synonym: "agrichemicals" RELATED [ChEBI] synonym: "agricultural chemicals" RELATED [ChEBI] synonym: "agrochemicals" RELATED [ChEBI] xref: Wikipedia:Agrochemical is_a: CHEBI:33232 ! application [Term] id: CHEBI:33287 name: fertilizer namespace: chebi_ontology def: "A fertilizer is any substance that is added to soil or water to assist the growth of plants." [] subset: 3_STAR synonym: "fertiliser" RELATED [ChEBI] synonym: "fertilizers" RELATED [ChEBI] is_a: CHEBI:33286 ! agrochemical [Term] id: CHEBI:33295 name: diagnostic agent namespace: chebi_ontology def: "A substance administered to aid diagnosis of a disease." [] subset: 3_STAR synonym: "diagnostic aid" RELATED [ChEBI] is_a: CHEBI:52217 ! pharmaceutical [Term] id: CHEBI:33296 name: alkali metal molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms of an alkali metal." [] subset: 3_STAR synonym: "alkali metal molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:22314 ! alkali metal atom [Term] id: CHEBI:33300 name: pnictogen namespace: chebi_ontology def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." [] subset: 3_STAR synonym: "group 15 elements" RELATED [ChEBI] synonym: "group V elements" RELATED [ChEBI] synonym: "nitrogenoideos" RELATED [ChEBI] synonym: "nitrogenoides" RELATED [ChEBI] synonym: "pnictogene" RELATED [ChEBI] synonym: "pnictogenes" RELATED [ChEBI] synonym: "pnictogens" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33302 name: pnictogen molecular entity namespace: chebi_ontology def: "A p-block molecular entity containing any pnictogen." [] subset: 3_STAR synonym: "pnictogen molecular entities" RELATED [ChEBI] synonym: "pnictogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33300 ! pnictogen [Term] id: CHEBI:33303 name: chalcogen namespace: chebi_ontology def: "Any p-block element belonging to the group 16 family of the periodic table." [] subset: 3_STAR synonym: "anfigeno" RELATED [ChEBI] synonym: "anfigenos" RELATED [ChEBI] synonym: "calcogeno" RELATED [ChEBI] synonym: "calcogenos" RELATED [ChEBI] synonym: "chalcogen" EXACT IUPAC_NAME [IUPAC] synonym: "chalcogene" RELATED [ChEBI] synonym: "chalcogenes" RELATED [ChEBI] synonym: "chalcogens" EXACT IUPAC_NAME [IUPAC] synonym: "Chalkogen" RELATED [ChEBI] synonym: "Chalkogene" RELATED [ChEBI] synonym: "group 16 elements" RELATED [ChEBI] synonym: "group VI elements" RELATED [ChEBI] xref: PMID:17084588 {source="Europe PMC"} is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33304 name: chalcogen molecular entity namespace: chebi_ontology def: "Any p-block molecular entity containing a chalcogen." [] subset: 3_STAR synonym: "chalcogen compounds" RELATED [ChEBI] synonym: "chalcogen molecular entities" RELATED [ChEBI] synonym: "chalcogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33303 ! chalcogen [Term] id: CHEBI:33306 name: carbon group element atom namespace: chebi_ontology subset: 3_STAR synonym: "carbon group element" RELATED [ChEBI] synonym: "carbon group elements" RELATED [ChEBI] synonym: "carbonoides" RELATED [ChEBI] synonym: "cristallogene" RELATED [ChEBI] synonym: "cristallogenes" RELATED [ChEBI] synonym: "group 14 elements" EXACT IUPAC_NAME [IUPAC] synonym: "group IV elements" RELATED [ChEBI] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33308 name: carboxylic ester namespace: chebi_ontology alt_id: CHEBI:13204 alt_id: CHEBI:23028 alt_id: CHEBI:3408 def: "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." [] subset: 3_STAR synonym: "a carboxylic ester" RELATED [UniProt] synonym: "carboxylic acid esters" RELATED [ChEBI] synonym: "Carboxylic ester" EXACT [KEGG_COMPOUND] synonym: "carboxylic esters" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C02391 xref: Wikipedia:Ester is_a: CHEBI:35701 ! ester is_a: CHEBI:36586 ! carbonyl compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)O[*]" xsd:string [Term] id: CHEBI:33317 name: boron group element atom namespace: chebi_ontology subset: 3_STAR synonym: "boron group element" RELATED [ChEBI] synonym: "boron group elements" RELATED [ChEBI] synonym: "Element der Borgruppe" RELATED [ChEBI] synonym: "group 13 elements" EXACT IUPAC_NAME [IUPAC] synonym: "group III elements" RELATED [ChEBI] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33318 name: main group element atom namespace: chebi_ontology def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." [] subset: 3_STAR synonym: "Hauptgruppenelement" RELATED [ChEBI] synonym: "Hauptgruppenelemente" RELATED [ChEBI] synonym: "main group element" RELATED [ChEBI] synonym: "main group elements" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33338 name: aryl group namespace: chebi_ontology def: "A group derived from an arene by removal of a hydrogen atom from a ring carbon atom." [] subset: 3_STAR synonym: "aryl groups" EXACT IUPAC_NAME [IUPAC] synonym: "Arylgruppe" RELATED [ChEBI] synonym: "groupe aryle" RELATED [IUPAC] synonym: "grupos arilo" RELATED [IUPAC] is_a: CHEBI:33248 ! hydrocarbyl group relationship: is_substituent_group_from CHEBI:33658 ! arene [Term] id: CHEBI:33362 name: nickel group element atom namespace: chebi_ontology subset: 3_STAR synonym: "group 10 elements" EXACT IUPAC_NAME [IUPAC] synonym: "nickel group element" RELATED [ChEBI] synonym: "nickel group elements" RELATED [ChEBI] is_a: CHEBI:33561 ! d-block element atom [Term] id: CHEBI:33364 name: platinum namespace: chebi_ontology subset: 3_STAR synonym: "78Pt" RELATED [IUPAC] synonym: "Platin" RELATED [ChEBI] synonym: "platine" RELATED [ChEBI] synonym: "platino" RELATED [ChEBI] synonym: "platinum" EXACT IUPAC_NAME [IUPAC] synonym: "Pt" RELATED [IUPAC] xref: CAS:7440-06-4 {source="NIST Chemistry WebBook"} xref: CAS:7440-06-4 {source="ChemIDplus"} xref: WebElements:Pt is_a: CHEBI:33362 ! nickel group element atom is_a: CHEBI:33365 ! platinum group metal atom property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Pt" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Pt" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BASFCYQUMIYNBI-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "195.078" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "194.96479" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Pt]" xsd:string [Term] id: CHEBI:33365 name: platinum group metal atom namespace: chebi_ontology subset: 3_STAR synonym: "PGM" RELATED [ChEBI] synonym: "Platinmetalle" RELATED [ChEBI] synonym: "platinoid" RELATED [ChEBI] synonym: "Platinoide" RELATED [ChEBI] synonym: "platinum group metal" RELATED [ChEBI] synonym: "platinum group metals" RELATED [ChEBI] synonym: "platinum metals" RELATED [ChEBI] is_a: CHEBI:27081 ! transition element atom [Term] id: CHEBI:33366 name: copper group element atom namespace: chebi_ontology subset: 3_STAR synonym: "coinage metals" RELATED [ChEBI] synonym: "copper group element" RELATED [ChEBI] synonym: "copper group elements" RELATED [ChEBI] synonym: "group 11 elements" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33561 ! d-block element atom [Term] id: CHEBI:33402 name: sulfur oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "oxoacids of sulfur" RELATED [ChEBI] synonym: "sulfur oxoacids" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33484 ! chalcogen oxoacid [Term] id: CHEBI:33405 name: hydracid namespace: chebi_ontology def: "A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [] subset: 3_STAR synonym: "hydracid" EXACT IUPAC_NAME [IUPAC] synonym: "hydracids" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33608 ! hydrogen molecular entity relationship: has_role CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:33408 name: pnictogen oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen oxoacids" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_role CHEBI:138103 ! inorganic acid [Term] id: CHEBI:33424 name: sulfur oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "sulfur oxoacid derivative" EXACT [ChEBI] synonym: "sulfur oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33241 ! oxoacid derivative [Term] id: CHEBI:33429 name: monoatomic monoanion namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic monoanions" RELATED [ChEBI] is_a: CHEBI:23905 ! monoatomic anion is_a: CHEBI:36830 ! monoanion property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*-]" xsd:string [Term] id: CHEBI:33431 name: elemental chlorine namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:23117 ! chlorine molecular entity is_a: CHEBI:33434 ! elemental halogen [Term] id: CHEBI:33432 name: monoatomic chlorine namespace: chebi_ontology subset: 3_STAR synonym: "atomic chlorine" RELATED [ChEBI] is_a: CHEBI:33431 ! elemental chlorine is_a: CHEBI:33433 ! monoatomic halogen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Cl" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "35.453" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "34.96885" xsd:string [Term] id: CHEBI:33433 name: monoatomic halogen namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic halogens" RELATED [ChEBI] is_a: CHEBI:33238 ! monoatomic entity [Term] id: CHEBI:33434 name: elemental halogen namespace: chebi_ontology subset: 3_STAR synonym: "elemental halogen" EXACT [ChEBI] synonym: "elemental halogens" RELATED [ChEBI] is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33452 name: benzylic group namespace: chebi_ontology def: "Arylmethyl groups and derivatives formed by substitution: ArCR2-." [] subset: 3_STAR synonym: "benzylic group" EXACT [IUPAC] synonym: "benzylic groups" EXACT IUPAC_NAME [IUPAC] synonym: "benzylic groups" RELATED [ChEBI] synonym: "groupe benzylique" RELATED [IUPAC] is_a: CHEBI:33249 ! organyl group [Term] id: CHEBI:33457 name: phosphorus oxoacid namespace: chebi_ontology def: "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." [] subset: 3_STAR synonym: "oxoacids of phosphorus" RELATED [ChEBI] synonym: "Oxosaeure des Phosphors" RELATED [ChEBI] synonym: "phosphorus oxoacid" EXACT [ChEBI] synonym: "phosphorus oxoacids" RELATED [ChEBI] is_a: CHEBI:33408 ! pnictogen oxoacid is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives [Term] id: CHEBI:33459 name: pnictogen oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen oxoanion" EXACT [ChEBI] synonym: "pnictogen oxoanions" RELATED [ChEBI] is_a: CHEBI:33302 ! pnictogen molecular entity is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33461 name: phosphorus oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "oxoanions of phosphorus" RELATED [ChEBI] synonym: "phosphorus oxoanion" EXACT [ChEBI] synonym: "phosphorus oxoanions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion is_a: CHEBI:26082 ! phosphorus molecular entity is_a: CHEBI:33459 ! pnictogen oxoanion [Term] id: CHEBI:33482 name: sulfur oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "oxoanions of sulfur" RELATED [ChEBI] synonym: "sulfur oxoanion" EXACT [ChEBI] synonym: "sulfur oxoanions" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33485 ! chalcogen oxoanion [Term] id: CHEBI:33484 name: chalcogen oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen oxoacid" EXACT [ChEBI] synonym: "chalcogen oxoacids" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid relationship: has_role CHEBI:138103 ! inorganic acid [Term] id: CHEBI:33485 name: chalcogen oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen oxoanion" EXACT [ChEBI] synonym: "chalcogen oxoanions" RELATED [ChEBI] is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33497 name: transition element molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms of a transition element." [] subset: 3_STAR synonym: "transition element molecular entities" RELATED [ChEBI] synonym: "transition metal molecular entity" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:27081 ! transition element atom [Term] id: CHEBI:33504 name: alkali metal cation namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal cations" RELATED [ChEBI] is_a: CHEBI:25213 ! metal cation [Term] id: CHEBI:33515 name: transition element cation namespace: chebi_ontology subset: 3_STAR synonym: "transition element cations" RELATED [ChEBI] synonym: "transition metal cation" RELATED [ChEBI] is_a: CHEBI:25213 ! metal cation [Term] id: CHEBI:33521 name: metal atom namespace: chebi_ontology alt_id: CHEBI:25217 alt_id: CHEBI:6788 def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." [] subset: 3_STAR synonym: "elemental metal" RELATED [ChEBI] synonym: "elemental metals" RELATED [ChEBI] synonym: "metal element" RELATED [ChEBI] synonym: "metal elements" RELATED [ChEBI] synonym: "metals" RELATED [ChEBI] xref: KEGG:C00050 xref: PMID:21784043 {source="Europe PMC"} xref: Wikipedia:Metal is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33543 name: sulfonate namespace: chebi_ontology def: "The sulfur oxoanion formed by deprotonation of sulfonic acid." [] subset: 3_STAR synonym: "[SHO3](-)" RELATED [IUPAC] synonym: "hydridotrioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "SHO3(-)" RELATED [IUPAC] synonym: "sulfonates" RELATED [ChEBI] xref: Gmelin:971569 {source="Gmelin"} is_a: CHEBI:33482 ! sulfur oxoanion relationship: is_conjugate_base_of CHEBI:29214 ! sulfonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BDHFUVZGWQCTTF-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "81.07214" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "80.96519" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]S([O-])(=O)=O" xsd:string [Term] id: CHEBI:33551 name: organosulfonic acid namespace: chebi_ontology def: "An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon." [] subset: 3_STAR synonym: "organosulfonic acids" RELATED [ChEBI] synonym: "sulfonic acids" RELATED [ChEBI] is_a: CHEBI:33261 ! organosulfur compound is_a: CHEBI:33552 ! sulfonic acid derivative is_a: CHEBI:64709 ! organic acid relationship: has_part CHEBI:29922 ! sulfo group relationship: has_part CHEBI:33249 ! organyl group relationship: is_conjugate_acid_of CHEBI:33554 ! organosulfonate oxoanion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO3SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "81.07100" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "80.96464" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OS([*])(=O)=O" xsd:string [Term] id: CHEBI:33552 name: sulfonic acid derivative namespace: chebi_ontology subset: 3_STAR synonym: "derivatives of sulfonic acid" RELATED [ChEBI] synonym: "sulfonic acid derivative" EXACT [ChEBI] synonym: "sulfonic acid derivatives" RELATED [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative relationship: has_functional_parent CHEBI:29214 ! sulfonic acid [Term] id: CHEBI:33554 name: organosulfonate oxoanion namespace: chebi_ontology def: "An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid." [] subset: 3_STAR synonym: "organosulfonate" RELATED [ChEBI] synonym: "organosulfonate oxoanions" RELATED [ChEBI] synonym: "organosulfonates" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion relationship: has_functional_parent CHEBI:33543 ! sulfonate relationship: is_conjugate_base_of CHEBI:33551 ! organosulfonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O3SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "80.064" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "79.95681" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*S([O-])(=O)=O" xsd:string [Term] id: CHEBI:33555 name: arenesulfonic acid namespace: chebi_ontology def: "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an aryl group." [] subset: 3_STAR synonym: "arenesulfonic acids" RELATED [ChEBI] synonym: "arylsulfonic acid" RELATED [ChEBI] synonym: "arylsulfonic acids" RELATED [ChEBI] is_a: CHEBI:33551 ! organosulfonic acid relationship: has_part CHEBI:33338 ! aryl group relationship: is_conjugate_acid_of CHEBI:22713 ! arenesulfonate oxoanion [Term] id: CHEBI:33558 name: alpha-amino-acid anion namespace: chebi_ontology def: "An amino-acid anion obtained by deprotonation of any alpha-amino acid." [] subset: 3_STAR synonym: "alpha-amino acid anions" RELATED [ChEBI] synonym: "alpha-amino-acid anion" EXACT [ChEBI] synonym: "alpha-amino-acid anions" RELATED [ChEBI] is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33559 name: s-block element atom namespace: chebi_ontology subset: 3_STAR synonym: "s-block element" RELATED [ChEBI] synonym: "s-block elements" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33560 name: p-block element atom namespace: chebi_ontology def: "Any main group element atom belonging to the p-block of the periodic table." [] subset: 3_STAR synonym: "p-block element" RELATED [ChEBI] synonym: "p-block elements" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom [Term] id: CHEBI:33561 name: d-block element atom namespace: chebi_ontology subset: 3_STAR synonym: "d-block element" RELATED [ChEBI] synonym: "d-block elements" RELATED [ChEBI] is_a: CHEBI:27081 ! transition element atom [Term] id: CHEBI:33570 name: benzenediols namespace: chebi_ontology alt_id: CHEBI:22705 alt_id: CHEBI:22711 subset: 3_STAR is_a: CHEBI:33853 ! phenols [Term] id: CHEBI:33575 name: carboxylic acid namespace: chebi_ontology alt_id: CHEBI:13428 alt_id: CHEBI:13627 alt_id: CHEBI:23027 def: "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." [] subset: 3_STAR synonym: "acide carboxylique" RELATED [IUPAC] synonym: "acides carboxyliques" RELATED [IUPAC] synonym: "acido carboxilico" RELATED [IUPAC] synonym: "acidos carboxilicos" RELATED [IUPAC] synonym: "Carbonsaeure" RELATED [ChEBI] synonym: "Carbonsaeuren" RELATED [ChEBI] synonym: "carboxylic acid" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Karbonsaeure" RELATED [ChEBI] synonym: "RC(=O)OH" RELATED [IUPAC] xref: PMID:17147560 {source="Europe PMC"} xref: PMID:18433345 {source="Europe PMC"} xref: Wikipedia:Carboxylic_acid is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36586 ! carbonyl compound is_a: CHEBI:64709 ! organic acid relationship: has_part CHEBI:46883 ! carboxy group relationship: is_conjugate_acid_of CHEBI:29067 ! carboxylic acid anion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01740" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string [Term] id: CHEBI:33576 name: sulfur-containing carboxylic acid namespace: chebi_ontology def: "Any carboxylic acid having a sulfur substituent." [] subset: 3_STAR synonym: "S-containing carboxylic acid" RELATED [ChEBI] synonym: "S-containing carboxylic acids" RELATED [ChEBI] synonym: "sulfur-containing carboxylic acids" RELATED [ChEBI] is_a: CHEBI:33261 ! organosulfur compound is_a: CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:33579 name: main group molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." [] subset: 3_STAR synonym: "main group compounds" RELATED [ChEBI] synonym: "main group molecular entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:33318 ! main group element atom [Term] id: CHEBI:33581 name: boron group molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "boron group molecular entities" RELATED [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33317 ! boron group element atom [Term] id: CHEBI:33582 name: carbon group molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "carbon group molecular entities" RELATED [ChEBI] synonym: "carbon group molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33306 ! carbon group element atom [Term] id: CHEBI:33595 name: cyclic compound namespace: chebi_ontology def: "Any molecule that consists of a series of atoms joined together to form a ring." [] subset: 3_STAR synonym: "cyclic compounds" RELATED [ChEBI] xref: Wikipedia:Cyclic_compound is_a: CHEBI:25367 ! molecule [Term] id: CHEBI:33597 name: homocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of the same element only." [] subset: 3_STAR synonym: "homocyclic compound" EXACT IUPAC_NAME [IUPAC] synonym: "homocyclic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "isocyclic compounds" RELATED [IUPAC] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33598 name: carbocyclic compound namespace: chebi_ontology def: "A homocyclic compound in which all of the ring members are carbon atoms." [] subset: 3_STAR synonym: "carbocycle" RELATED [ChEBI] synonym: "carbocyclic compound" EXACT IUPAC_NAME [IUPAC] synonym: "carbocyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33597 ! homocyclic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:33608 name: hydrogen molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "hydrogen compounds" RELATED [ChEBI] synonym: "hydrogen molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:49637 ! hydrogen atom [Term] id: CHEBI:33619 name: boron oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "boron oxoanion" EXACT [ChEBI] synonym: "boron oxoanions" RELATED [ChEBI] is_a: CHEBI:22916 ! boron molecular entity is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33635 name: polycyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33636 name: bicyclic compound namespace: chebi_ontology def: "A molecule that features two fused rings." [] subset: 3_STAR synonym: "bicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33637 name: ortho-fused compound namespace: chebi_ontology def: "A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms." [] subset: 3_STAR synonym: "ortho-fused compounds" RELATED [ChEBI] synonym: "ortho-fused polycyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:35293 ! fused compound [Term] id: CHEBI:33639 name: ortho- and peri-fused compound namespace: chebi_ontology def: "A polycyclic compound in which one ring contains two, and only two, atoms in common with each of two or more rings of a contiguous series of rings. Such compounds have n common faces and less than 2n common atoms." [] subset: 3_STAR synonym: "ortho- and peri-fused compounds" RELATED [ChEBI] synonym: "ortho- and peri-fused polycyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:35293 ! fused compound [Term] id: CHEBI:33653 name: aliphatic compound namespace: chebi_ontology def: "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." [] subset: 3_STAR synonym: "aliphatic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33655 name: aromatic compound namespace: chebi_ontology def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." [] subset: 3_STAR synonym: "aromatic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "aromatic molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "aromatics" RELATED [ChEBI] synonym: "aromatische Verbindungen" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33658 name: arene namespace: chebi_ontology def: "Any monocyclic or polycyclic aromatic hydrocarbon." [] subset: 3_STAR synonym: "arene" EXACT IUPAC_NAME [IUPAC] synonym: "arenes" EXACT IUPAC_NAME [IUPAC] synonym: "aromatic hydrocarbons" RELATED [IUPAC] is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:33663 ! cyclic hydrocarbon [Term] id: CHEBI:33659 name: organic aromatic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic aromatic compounds" RELATED [ChEBI] is_a: CHEBI:33655 ! aromatic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:33661 name: monocyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "monocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33662 name: annulene namespace: chebi_ontology def: "A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms." [] subset: 3_STAR synonym: "annulene" EXACT IUPAC_NAME [IUPAC] synonym: "annulenes" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33664 ! monocyclic hydrocarbon [Term] id: CHEBI:33663 name: cyclic hydrocarbon namespace: chebi_ontology subset: 3_STAR synonym: "cyclic hydrocarbon" EXACT [ChEBI] synonym: "cyclic hydrocarbons" RELATED [ChEBI] is_a: CHEBI:24632 ! hydrocarbon is_a: CHEBI:33598 ! carbocyclic compound [Term] id: CHEBI:33664 name: monocyclic hydrocarbon namespace: chebi_ontology subset: 3_STAR synonym: "monocyclic hydrocarbon" EXACT [ChEBI] synonym: "monocyclic hydrocarbons" EXACT IUPAC_NAME [IUPAC] synonym: "monocyclic hydrocarbons" RELATED [ChEBI] is_a: CHEBI:33663 ! cyclic hydrocarbon [Term] id: CHEBI:33666 name: polycyclic hydrocarbon namespace: chebi_ontology subset: 3_STAR synonym: "polycyclic hydrocarbon" EXACT IUPAC_NAME [IUPAC] synonym: "polycyclic hydrocarbons" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33663 ! cyclic hydrocarbon is_a: CHEBI:35294 ! carbopolycyclic compound [Term] id: CHEBI:33670 name: heteromonocyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "heteromonocyclic compound" EXACT IUPAC_NAME [IUPAC] synonym: "heteromonocyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33661 ! monocyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33671 name: heteropolycyclic compound namespace: chebi_ontology def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." [] subset: 3_STAR synonym: "heteropolycyclic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "polyheterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33672 name: heterobicyclic compound namespace: chebi_ontology def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." [] subset: 3_STAR synonym: "heterobicyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33636 ! bicyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33674 name: s-block molecular entity namespace: chebi_ontology def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." [] subset: 3_STAR synonym: "s-block compounds" RELATED [ChEBI] synonym: "s-block molecular entities" RELATED [ChEBI] synonym: "s-block molecular entity" EXACT [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33559 ! s-block element atom [Term] id: CHEBI:33675 name: p-block molecular entity namespace: chebi_ontology def: "A main group molecular entity that contains one or more atoms of a p-block element." [] subset: 3_STAR synonym: "p-block compounds" RELATED [ChEBI] synonym: "p-block molecular entities" RELATED [ChEBI] synonym: "p-block molecular entitiy" RELATED [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33676 name: d-block molecular entity namespace: chebi_ontology def: "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." [] subset: 3_STAR synonym: "d-block compounds" RELATED [ChEBI] synonym: "d-block molecular entities" RELATED [ChEBI] synonym: "d-block molecular entity" EXACT [ChEBI] is_a: CHEBI:33497 ! transition element molecular entity relationship: has_part CHEBI:33561 ! d-block element atom [Term] id: CHEBI:33692 name: hydrides namespace: chebi_ontology def: "Hydrides are chemical compounds of hydrogen with other chemical elements." [] subset: 3_STAR is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:33694 name: biomacromolecule namespace: chebi_ontology def: "A macromolecule formed by a living organism." [] subset: 3_STAR synonym: "biomacromolecules" RELATED [ChEBI] synonym: "biopolymer" EXACT IUPAC_NAME [IUPAC] synonym: "Biopolymere" RELATED [ChEBI] synonym: "biopolymers" RELATED [ChEBI] is_a: CHEBI:33839 ! macromolecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33695 name: information biomacromolecule namespace: chebi_ontology subset: 3_STAR synonym: "genetically encoded biomacromolecules" RELATED [ChEBI] synonym: "genetically encoded biopolymers" RELATED [ChEBI] synonym: "information biomacromolecules" RELATED [ChEBI] synonym: "information biopolymers" RELATED [ChEBI] synonym: "information macromolecule" RELATED [ChEBI] synonym: "information macromolecules" RELATED [ChEBI] is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:33696 name: nucleic acid namespace: chebi_ontology def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." [] subset: 3_STAR synonym: "acide nucleique" RELATED [ChEBI] synonym: "acides nucleiques" RELATED [ChEBI] synonym: "acido nucleico" RELATED [ChEBI] synonym: "acidos nucleicos" RELATED [ChEBI] synonym: "NA" RELATED [ChEBI] synonym: "nucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Nukleinsaeure" RELATED [ChEBI] synonym: "Nukleinsaeuren" RELATED [ChEBI] is_a: CHEBI:15986 ! polynucleotide relationship: has_part CHEBI:33791 ! canonical nucleoside residue relationship: has_part CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:33702 name: polyatomic cation namespace: chebi_ontology def: "A cation consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic cations" RELATED [ChEBI] is_a: CHEBI:36358 ! polyatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:33703 name: amino-acid cation namespace: chebi_ontology subset: 3_STAR synonym: "amino acid cation" RELATED [ChEBI] synonym: "amino-acid cation" EXACT [ChEBI] synonym: "amino-acid cations" RELATED [ChEBI] is_a: CHEBI:33702 ! polyatomic cation [Term] id: CHEBI:33704 name: alpha-amino acid namespace: chebi_ontology alt_id: CHEBI:10208 alt_id: CHEBI:13779 alt_id: CHEBI:22442 alt_id: CHEBI:2642 def: "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." [] subset: 3_STAR synonym: "alpha-amino acid" EXACT IUPAC_NAME [IUPAC] synonym: "alpha-amino acids" RELATED [JCBN] synonym: "alpha-amino acids" RELATED [ChEBI] synonym: "alpha-amino carboxylic acids" RELATED [IUPAC] synonym: "Amino acid" RELATED [KEGG_COMPOUND] synonym: "Amino acids" RELATED [KEGG_COMPOUND] xref: KEGG:C00045 xref: KEGG:C05167 is_a: CHEBI:33709 ! amino acid relationship: is_conjugate_acid_of CHEBI:33558 ! alpha-amino-acid anion relationship: is_tautomer_of CHEBI:78608 ! alpha-amino acid zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([*])C(O)=O" xsd:string [Term] id: CHEBI:33708 name: amino-acid residue namespace: chebi_ontology def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." [] subset: 3_STAR synonym: "amino acid residue" RELATED [ChEBI] synonym: "amino-acid residue" EXACT IUPAC_NAME [IUPAC] synonym: "amino-acid residues" RELATED [JCBN] is_a: CHEBI:33247 ! organic group relationship: is_substituent_group_from CHEBI:33709 ! amino acid [Term] id: CHEBI:33709 name: amino acid namespace: chebi_ontology alt_id: CHEBI:13815 alt_id: CHEBI:22477 def: "A carboxylic acid containing one or more amino groups." [] subset: 3_STAR synonym: "amino acids" RELATED [ChEBI] synonym: "Aminocarbonsaeure" RELATED [ChEBI] synonym: "Aminokarbonsaeure" RELATED [ChEBI] synonym: "Aminosaeure" RELATED [ChEBI] xref: Wikipedia:Amino_acid is_a: CHEBI:33575 ! carboxylic acid is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_acid_of CHEBI:37022 ! amino-acid anion [Term] id: CHEBI:33719 name: alpha-amino-acid cation namespace: chebi_ontology subset: 3_STAR synonym: "alpha-amino acid cations" RELATED [ChEBI] synonym: "alpha-amino-acid cation" EXACT [ChEBI] synonym: "alpha-amino-acid cations" RELATED [ChEBI] is_a: CHEBI:33703 ! amino-acid cation [Term] id: CHEBI:33745 name: copper group molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "copper group molecular entities" RELATED [ChEBI] synonym: "copper group molecular entity" EXACT [ChEBI] is_a: CHEBI:33676 ! d-block molecular entity relationship: has_part CHEBI:33366 ! copper group element atom [Term] id: CHEBI:33747 name: nickel group molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "nickel group molecular entities" RELATED [ChEBI] synonym: "nickel group molecular entity" EXACT [ChEBI] is_a: CHEBI:33676 ! d-block molecular entity relationship: has_part CHEBI:33362 ! nickel group element atom [Term] id: CHEBI:33749 name: platinum molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "platinum compounds" RELATED [ChEBI] synonym: "platinum molecular entities" RELATED [ChEBI] synonym: "platinum molecular entity" EXACT [ChEBI] is_a: CHEBI:33747 ! nickel group molecular entity relationship: has_part CHEBI:33364 ! platinum [Term] id: CHEBI:33791 name: canonical nucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical nucleoside residues" RELATED [ChEBI] synonym: "common nucleoside residues" RELATED [CBN] synonym: "nucleoside residue" RELATED [CBN] synonym: "standard nucleoside residues" RELATED [ChEBI] is_a: CHEBI:50320 ! nucleoside residue [Term] id: CHEBI:33793 name: canonical deoxyribonucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical deoxyribonucleoside residues" RELATED [ChEBI] synonym: "common 2'-deoxyribonucleoside residue" RELATED [CBN] synonym: "common 2'-deoxyribonucleoside residues" RELATED [CBN] synonym: "dN" RELATED [CBN] synonym: "dNuc" RELATED [CBN] synonym: "standard deoxyribonucleoside residues" RELATED [ChEBI] is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33822 name: organic hydroxy compound namespace: chebi_ontology alt_id: CHEBI:64710 def: "An organic compound having at least one hydroxy group attached to a carbon atom." [] subset: 3_STAR synonym: "hydroxy compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organic alcohol" RELATED [ChEBI] synonym: "organic hydroxy compounds" RELATED [ChEBI] is_a: CHEBI:24651 ! hydroxides is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33832 name: organic cyclic compound namespace: chebi_ontology def: "Any organic molecule that consists of atoms connected in the form of a ring." [] subset: 3_STAR synonym: "organic cyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:33833 name: heteroarene namespace: chebi_ontology def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." [] subset: 3_STAR synonym: "hetarenes" RELATED [IUPAC] synonym: "heteroarenes" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:33836 name: benzenoid aromatic compound namespace: chebi_ontology subset: 3_STAR synonym: "benzenoid aromatic compounds" RELATED [ChEBI] synonym: "benzenoid compound" RELATED [ChEBI] is_a: CHEBI:33598 ! carbocyclic compound is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:33838 name: nucleoside namespace: chebi_ontology alt_id: CHEBI:13661 alt_id: CHEBI:25611 alt_id: CHEBI:7647 def: "An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents." [] subset: 3_STAR synonym: "a nucleoside" RELATED [UniProt] synonym: "Nucleoside" EXACT [KEGG_COMPOUND] synonym: "nucleosides" EXACT IUPAC_NAME [IUPAC] synonym: "nucleosides" RELATED [ChEBI] xref: KEGG:C00801 xref: Wikipedia:Nucleoside is_a: CHEBI:21731 ! N-glycosyl compound is_a: CHEBI:26912 ! oxolanes is_a: CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_functional_parent CHEBI:16646 ! carbohydrate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H8O3R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "116.115" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "116.04734" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO" xsd:string [Term] id: CHEBI:33839 name: macromolecule namespace: chebi_ontology def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [] subset: 3_STAR synonym: "macromolecule" EXACT IUPAC_NAME [IUPAC] synonym: "macromolecules" RELATED [ChEBI] synonym: "polymer" RELATED [ChEBI] synonym: "polymer molecule" RELATED [IUPAC] synonym: "polymers" RELATED [ChEBI] xref: Wikipedia:Macromolecule is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:33842 name: aromatic annulene namespace: chebi_ontology subset: 3_STAR synonym: "aromatic annulenes" RELATED [ChEBI] is_a: CHEBI:33662 ! annulene is_a: CHEBI:33847 ! monocyclic arene [Term] id: CHEBI:33847 name: monocyclic arene namespace: chebi_ontology def: "A monocyclic aromatic hydrocarbon." [] subset: 3_STAR synonym: "monocyclic arenes" RELATED [ChEBI] is_a: CHEBI:33658 ! arene [Term] id: CHEBI:33848 name: polycyclic arene namespace: chebi_ontology def: "A polycyclic aromatic hydrocarbon." [] subset: 3_STAR synonym: "PAH" RELATED [ChEBI] synonym: "PAHs" RELATED [ChEBI] synonym: "polycyclic arenes" RELATED [ChEBI] synonym: "polycyclic aromatic hydrocarbons" RELATED [ChEBI] xref: PMID:15198916 {source="Europe PMC"} xref: PMID:25679824 {source="Europe PMC"} xref: Wikipedia:Polycyclic_aromatic_hydrocarbon is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33658 ! arene is_a: CHEBI:33666 ! polycyclic hydrocarbon relationship: has_role CHEBI:138015 ! endocrine disruptor relationship: has_role CHEBI:50903 ! carcinogenic agent [Term] id: CHEBI:33853 name: phenols namespace: chebi_ontology alt_id: CHEBI:13664 alt_id: CHEBI:13825 alt_id: CHEBI:25969 alt_id: CHEBI:2857 def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." [] subset: 3_STAR synonym: "a phenol" RELATED [UniProt] synonym: "arenols" RELATED [IUPAC] synonym: "Aryl alcohol" RELATED [KEGG_COMPOUND] synonym: "phenols" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C15584 xref: MetaCyc:Phenols xref: Wikipedia:Phenols is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:33822 ! organic hydroxy compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6HOR5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "89.072" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "89.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C(C(=C1*)*)*)*)*)O" xsd:string [Term] id: CHEBI:33856 name: aromatic amino acid namespace: chebi_ontology alt_id: CHEBI:13820 alt_id: CHEBI:22623 alt_id: CHEBI:2835 def: "An amino acid whose structure includes an aromatic ring." [] subset: 3_STAR synonym: "Aromatic amino acid" EXACT [KEGG_COMPOUND] synonym: "aromatic amino acids" RELATED [ChEBI] xref: KEGG:C01021 xref: Wikipedia:Aromatic_amino_acid is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:33709 ! amino acid relationship: is_conjugate_acid_of CHEBI:63473 ! aromatic amino-acid anion relationship: is_tautomer_of CHEBI:76042 ! aromatic amino-acid zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "88.085" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string [Term] id: CHEBI:33860 name: aromatic amine namespace: chebi_ontology alt_id: CHEBI:13827 alt_id: CHEBI:22622 alt_id: CHEBI:22646 alt_id: CHEBI:2834 alt_id: CHEBI:2863 def: "An amino compound in which the amino group is linked directly to an aromatic system." [] subset: 3_STAR synonym: "aromatic amines" RELATED [ChEBI] synonym: "aryl amine" RELATED [ChEBI] synonym: "aryl amines" RELATED [ChEBI] synonym: "arylamine" RELATED [ChEBI] synonym: "arylamines" RELATED [ChEBI] is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:33861 name: transition element coordination entity namespace: chebi_ontology subset: 3_STAR synonym: "transition element coordination entities" RELATED [ChEBI] synonym: "transition metal coordination compounds" RELATED [ChEBI] synonym: "transition metal coordination entities" RELATED [ChEBI] is_a: CHEBI:33240 ! coordination entity is_a: CHEBI:33497 ! transition element molecular entity [Term] id: CHEBI:33862 name: platinum coordination entity namespace: chebi_ontology subset: 3_STAR synonym: "platinum coordination compounds" RELATED [ChEBI] synonym: "platinum coordination entities" RELATED [ChEBI] synonym: "platinum coordination entity" EXACT [ChEBI] is_a: CHEBI:33749 ! platinum molecular entity is_a: CHEBI:33861 ! transition element coordination entity [Term] id: CHEBI:33893 name: reagent namespace: chebi_ontology def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." [] subset: 3_STAR synonym: "reactif" RELATED [IUPAC] synonym: "reactivo" RELATED [IUPAC] synonym: "reagent" EXACT IUPAC_NAME [IUPAC] synonym: "reagents" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:33937 name: macronutrient namespace: chebi_ontology def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." [] subset: 3_STAR synonym: "macronutrients" RELATED [ChEBI] is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:33958 name: halide salt namespace: chebi_ontology subset: 3_STAR synonym: "halide salts" RELATED [ChEBI] synonym: "halides" RELATED [ChEBI] is_a: CHEBI:24866 ! salt is_a: CHEBI:37578 ! halide relationship: has_part CHEBI:16042 ! halide anion [Term] id: CHEBI:34699 name: diethyl sulfate namespace: chebi_ontology subset: 2_STAR synonym: "DES" RELATED [KEGG_COMPOUND] synonym: "Diethyl sulfate" EXACT [KEGG_COMPOUND] xref: CAS:64-67-5 {source="KEGG COMPOUND"} xref: KEGG:C14706 is_a: CHEBI:29281 ! alkyl sulfate is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000527 ! diethyl sulfate equivalent_to: FBcv:0000527 ! diethyl sulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H10O4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H10O4S/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DENRZWYUOJLTMF-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "154.186" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "154.02998" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCOS(=O)(=O)OCC" xsd:string [Term] id: CHEBI:34873 name: N-nitrosodiethylamine namespace: chebi_ontology def: "A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom." [] subset: 3_STAR synonym: "1,1-diethyl-2-oxohydrazine" RELATED [NIST_Chemistry_WebBook] synonym: "DANA" RELATED [NIST_Chemistry_WebBook] synonym: "DEN" RELATED [NIST_Chemistry_WebBook] synonym: "Diethylnitrosamine" RELATED [KEGG_COMPOUND] synonym: "diethylnitrosoamine" RELATED [ChemIDplus] synonym: "N,N-diethylnitrosamine" RELATED [ChemIDplus] synonym: "N,N-diethylnitrosoamine" RELATED [ChemIDplus] synonym: "N-ethyl-N-nitrosoethanamine" EXACT IUPAC_NAME [IUPAC] synonym: "N-Nitrosodiethylamine" EXACT [KEGG_COMPOUND] synonym: "NDEA" RELATED [KEGG_COMPOUND] xref: Beilstein:1744991 {source="Beilstein"} xref: CAS:55-18-5 {source="NIST Chemistry WebBook"} xref: CAS:55-18-5 {source="ChemIDplus"} xref: CAS:55-18-5 {source="KEGG COMPOUND"} xref: KEGG:C14422 xref: PMID:24696076 {source="Europe PMC"} xref: PMID:24755254 {source="Europe PMC"} xref: Reaxys:1744991 {source="Reaxys"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35803 ! nitrosamine is_a: FBcv:0000735 ! N-nitrosodiethylamine equivalent_to: FBcv:0000735 ! N-nitrosodiethylamine relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:50908 ! hepatotoxic agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H10N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WBNQDOYYEUMPFS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "102.135" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "102.07931" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(CC)N=O" xsd:string [Term] id: CHEBI:35106 name: nitrogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "nitrogen hydrides" RELATED [ChEBI] is_a: CHEBI:35881 ! pnictogen hydride is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35107 name: azane namespace: chebi_ontology def: "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." [] subset: 3_STAR synonym: "azanes" RELATED [ChEBI] is_a: CHEBI:35106 ! nitrogen hydride [Term] id: CHEBI:35175 name: sulfate salt namespace: chebi_ontology subset: 3_STAR synonym: "sulfate salts" RELATED [ChEBI] synonym: "sulfates" RELATED [ChEBI] synonym: "sulphate salts" RELATED [ChEBI] synonym: "sulphates" RELATED [ChEBI] is_a: CHEBI:24866 ! salt is_a: CHEBI:26820 ! sulfates [Term] id: CHEBI:35221 name: antimetabolite namespace: chebi_ontology def: "A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." [] subset: 3_STAR synonym: "antimetabolite" EXACT IUPAC_NAME [IUPAC] synonym: "antimetabolites" RELATED [ChEBI] xref: Wikipedia:Antimetabolite is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:35222 name: inhibitor namespace: chebi_ontology def: "A substance that diminishes the rate of a chemical reaction." [] subset: 3_STAR synonym: "inhibidor" RELATED [ChEBI] synonym: "inhibiteur" RELATED [ChEBI] synonym: "inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "inhibitors" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:35223 name: catalyst namespace: chebi_ontology def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." [] subset: 3_STAR synonym: "catalizador" RELATED [ChEBI] synonym: "catalyseur" RELATED [ChEBI] synonym: "catalyst" EXACT IUPAC_NAME [IUPAC] synonym: "Katalysator" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:35237 name: cysteine zwitterion namespace: chebi_ontology subset: 3_STAR synonym: "(+)H3N-CH(CH2SH)-COO(-)" RELATED [ChEBI] synonym: "2-ammonio-3-mercaptopropanoate" RELATED [ChEBI] synonym: "2-ammonio-3-sulfanylpropanoate" EXACT IUPAC_NAME [IUPAC] synonym: "cysteine zwitterion" EXACT [IUPAC] xref: Gmelin:49992 {source="Gmelin"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_conjugate_acid_of CHEBI:32456 ! cysteinate(1-) relationship: is_conjugate_base_of CHEBI:32458 ! cysteinium relationship: is_tautomer_of CHEBI:15356 ! cysteine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H7NO2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "121.15922" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "121.01975" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C(CS)C([O-])=O" xsd:string [Term] id: CHEBI:35238 name: amino acid zwitterion namespace: chebi_ontology def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." [] subset: 3_STAR synonym: "amino acid zwitterion" EXACT [ChEBI] is_a: CHEBI:27369 ! zwitterion [Term] id: CHEBI:35274 name: ammonium ion derivative namespace: chebi_ontology def: "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." [] subset: 3_STAR synonym: "ammonium ion derivatives" RELATED [ChEBI] synonym: "azanium ion derivative" RELATED [ChEBI] synonym: "azanium ion derivatives" RELATED [ChEBI] is_a: CHEBI:33702 ! polyatomic cation is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_parent_hydride CHEBI:28938 ! ammonium [Term] id: CHEBI:35286 name: iminium ion namespace: chebi_ontology def: "Cations of structure R2C=N(+)R2." [] subset: 3_STAR synonym: "iminium cations" RELATED [ChEBI] synonym: "iminium ion" EXACT [ChEBI] synonym: "iminium ions" RELATED [ChEBI] is_a: CHEBI:25697 ! organic cation [Term] id: CHEBI:35293 name: fused compound namespace: chebi_ontology subset: 3_STAR synonym: "fused compounds" RELATED [ChEBI] synonym: "fused polycyclic compounds" RELATED [ChEBI] synonym: "fused-ring polycyclic compound" RELATED [ChEBI] synonym: "fused-ring polycyclic compounds" RELATED [ChEBI] synonym: "polycyclic fused-ring compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound [Term] id: CHEBI:35294 name: carbopolycyclic compound namespace: chebi_ontology def: "A polyclic compound in which all of the ring members are carbon atoms." [] subset: 3_STAR synonym: "carbopolycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33598 ! carbocyclic compound is_a: CHEBI:35295 ! homopolycyclic compound [Term] id: CHEBI:35295 name: homopolycyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "homopolycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33597 ! homocyclic compound is_a: CHEBI:33635 ! polycyclic compound [Term] id: CHEBI:35296 name: ortho-fused polycyclic arene namespace: chebi_ontology subset: 3_STAR synonym: "ortho-fused polycyclic arenes" RELATED [ChEBI] is_a: CHEBI:33848 ! polycyclic arene is_a: CHEBI:35427 ! ortho-fused polycyclic hydrocarbon [Term] id: CHEBI:35299 name: dibenz[a,h]anthracene namespace: chebi_ontology alt_id: CHEBI:18901 alt_id: CHEBI:34684 subset: 3_STAR synonym: "1,2:5,6-Dibenzanthracene" RELATED [KEGG_COMPOUND] synonym: "DBA" RELATED [ChemIDplus] synonym: "Dibenz[a,h]anthracene" EXACT [KEGG_COMPOUND] xref: CAS:53-70-3 {source="KEGG COMPOUND"} xref: CAS:53-70-3 {source="NIST Chemistry WebBook"} xref: CAS:53-70-3 {source="ChemIDplus"} xref: KEGG:C14325 is_a: CHEBI:35296 ! ortho-fused polycyclic arene is_a: FBcv:0000562 ! 1,2:5,6-dibenzanthracene equivalent_to: FBcv:0000562 ! 1,2:5,6-dibenzanthracene relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C22H14" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C22H14/c1-3-7-19-15(5-1)9-11-17-14-22-18(13-21(17)19)12-10-16-6-2-4-8-20(16)22/h1-14H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LHRCREOYAASXPZ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "278.34656" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "278.10955" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ccc2c(c1)ccc1cc3c(ccc4ccccc34)cc21" xsd:string [Term] id: CHEBI:35300 name: ortho- and peri-fused polycyclic arene namespace: chebi_ontology subset: 3_STAR synonym: "ortho- and peri-fused polycyclic arenes" RELATED [ChEBI] is_a: CHEBI:33639 ! ortho- and peri-fused compound is_a: CHEBI:33848 ! polycyclic arene [Term] id: CHEBI:35337 name: central nervous system stimulant namespace: chebi_ontology def: "Any drug that enhances the activity of the central nervous system." [] subset: 3_STAR synonym: "analeptic" RELATED [ChEBI] synonym: "analeptic agent" RELATED [ChEBI] synonym: "analeptic drug" RELATED [ChEBI] synonym: "analeptics" RELATED [ChEBI] synonym: "central nervous system stimulant" EXACT [ChEBI] synonym: "central stimulant" RELATED [ChEBI] synonym: "CNS stimulant" RELATED [ChEBI] xref: Wikipedia:Central_nervous_system_stimulants is_a: CHEBI:35470 ! central nervous system drug [Term] id: CHEBI:35352 name: organonitrogen compound namespace: chebi_ontology def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." [] subset: 3_STAR synonym: "organonitrogen compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organonitrogens" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35359 name: carboxamidine namespace: chebi_ontology def: "Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the -C(=NH)NH2 group including its carbon atom." [] subset: 3_STAR synonym: "Amidines" RELATED [KEGG_COMPOUND] synonym: "carboxamidines" EXACT IUPAC_NAME [IUPAC] synonym: "carboxamidines" RELATED [ChEBI] xref: KEGG:C06060 is_a: CHEBI:2634 ! amidine is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:35366 name: fatty acid namespace: chebi_ontology alt_id: CHEBI:13633 alt_id: CHEBI:24024 alt_id: CHEBI:4984 def: "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." [] subset: 3_STAR synonym: "acide gras" RELATED [ChEBI] synonym: "acides gras" RELATED [ChemIDplus] synonym: "acido graso" RELATED [ChEBI] synonym: "acidos grasos" RELATED [ChEBI] synonym: "Fatty acid" EXACT [KEGG_COMPOUND] synonym: "fatty acids" EXACT IUPAC_NAME [IUPAC] synonym: "fatty acids" RELATED [ChEBI] synonym: "Fettsaeure" RELATED [ChEBI] synonym: "Fettsaeuren" RELATED [ChEBI] xref: KEGG:C00162 xref: PMID:14287444 {source="Europe PMC"} xref: PMID:14300208 {source="Europe PMC"} xref: PMID:14328676 {source="Europe PMC"} xref: Wikipedia:Fatty_acid is_a: CHEBI:18059 ! lipid is_a: CHEBI:25384 ! monocarboxylic acid relationship: is_conjugate_acid_of CHEBI:28868 ! fatty acid anion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01740" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string [Term] id: CHEBI:35406 name: oxoanion namespace: chebi_ontology alt_id: CHEBI:33274 alt_id: CHEBI:33436 def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." [] subset: 3_STAR synonym: "oxoacid anions" RELATED [ChEBI] synonym: "oxoanion" EXACT [ChEBI] synonym: "oxoanions" RELATED [ChEBI] is_a: CHEBI:25741 ! oxide is_a: CHEBI:33273 ! polyatomic anion [Term] id: CHEBI:35426 name: ortho-fused bicyclic arene namespace: chebi_ontology subset: 3_STAR synonym: "ortho-fused bicyclic arene" EXACT [ChEBI] synonym: "ortho-fused bicyclic arenes" RELATED [ChEBI] is_a: CHEBI:35296 ! ortho-fused polycyclic arene is_a: CHEBI:35428 ! ortho-fused bicyclic hydrocarbon [Term] id: CHEBI:35427 name: ortho-fused polycyclic hydrocarbon namespace: chebi_ontology subset: 3_STAR synonym: "ortho-fused polycyclic hydrocarbon" EXACT [ChEBI] synonym: "ortho-fused polycyclic hydrocarbons" RELATED [ChEBI] is_a: CHEBI:33637 ! ortho-fused compound [Term] id: CHEBI:35428 name: ortho-fused bicyclic hydrocarbon namespace: chebi_ontology subset: 3_STAR synonym: "ortho-fused bicyclic hydrocarbon" EXACT [ChEBI] synonym: "ortho-fused bicyclic hydrocarbons" RELATED [ChEBI] is_a: CHEBI:33637 ! ortho-fused compound is_a: CHEBI:36785 ! carbobicyclic compound [Term] id: CHEBI:35441 name: antiinfective agent namespace: chebi_ontology def: "A substance used in the prophylaxis or therapy of infectious diseases." [] subset: 3_STAR synonym: "anti-infective agents" RELATED [ChEBI] synonym: "anti-infective drugs" RELATED [ChEBI] synonym: "antiinfective agents" RELATED [ChEBI] synonym: "antiinfective drug" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35442 name: antiparasitic agent namespace: chebi_ontology def: "A substance used to treat or prevent parasitic infections." [] subset: 3_STAR synonym: "antiparasitic drugs" RELATED [ChEBI] synonym: "antiparasitics" RELATED [ChEBI] synonym: "parasiticides" RELATED [ChEBI] xref: Wikipedia:Antiparasitic is_a: CHEBI:35441 ! antiinfective agent [Term] id: CHEBI:35443 name: anthelminthic drug namespace: chebi_ontology def: "Substance intended to kill parasitic worms (helminths)." [] subset: 3_STAR synonym: "anthelminthic" EXACT IUPAC_NAME [IUPAC] synonym: "anthelminthics" RELATED [ChEBI] synonym: "anthelmintic" RELATED [IUPAC] synonym: "anthelmintics" RELATED [ChEBI] synonym: "antihelminth" RELATED [ChEBI] synonym: "antihelmintico" RELATED [ChEBI] synonym: "vermifuge" RELATED [ChEBI] is_a: CHEBI:35442 ! antiparasitic agent [Term] id: CHEBI:35444 name: antinematodal drug namespace: chebi_ontology def: "A substance used in the treatment or control of nematode infestations." [] subset: 3_STAR synonym: "antinematodal agent" RELATED [ChEBI] synonym: "antinematodal drugs" RELATED [ChEBI] synonym: "antinematodals" RELATED [ChEBI] is_a: CHEBI:25491 ! nematicide is_a: CHEBI:35443 ! anthelminthic drug [Term] id: CHEBI:35470 name: central nervous system drug namespace: chebi_ontology def: "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." [] subset: 3_STAR synonym: "central nervous system agents" RELATED [ChEBI] synonym: "CNS agent" RELATED [ChEBI] synonym: "CNS drugs" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35471 name: psychotropic drug namespace: chebi_ontology def: "A loosely defined grouping of drugs that have effects on psychological function." [] subset: 3_STAR synonym: "psychoactive agent" RELATED [ChEBI] synonym: "psychoactive drugs" RELATED [ChEBI] synonym: "psychopharmaceuticals" RELATED [ChEBI] synonym: "psychotropic drugs" RELATED [ChEBI] xref: Wikipedia:Psychotropic_drug is_a: CHEBI:35470 ! central nervous system drug [Term] id: CHEBI:35479 name: alkali metal salt namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal salts" RELATED [ChEBI] is_a: CHEBI:24866 ! salt is_a: CHEBI:33296 ! alkali metal molecular entity [Term] id: CHEBI:35480 name: analgesic namespace: chebi_ontology def: "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms." [] subset: 3_STAR is_a: CHEBI:23888 ! drug is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:35481 name: non-narcotic analgesic namespace: chebi_ontology def: "A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors." [] subset: 3_STAR is_a: CHEBI:35480 ! analgesic [Term] id: CHEBI:35498 name: diuretic namespace: chebi_ontology def: "An agent that promotes the excretion of urine through its effects on kidney function." [] subset: 3_STAR synonym: "diuretics" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35504 name: addition compound namespace: chebi_ontology def: "An addition compound contains two or more simpler compounds that can be packed in a definite ratio into a crystal. The term covers donor-acceptor complexes (adducts) and a variety of lattice compounds." [] subset: 3_STAR synonym: "addition compounds" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:35552 name: heterocyclic organic fundamental parent namespace: chebi_ontology subset: 3_STAR synonym: "heterocyclic fundamental parent" RELATED [ChEBI] synonym: "heterocyclic organic fundamental parents" RELATED [ChEBI] synonym: "heterocyclic parent hydrides" EXACT IUPAC_NAME [IUPAC] synonym: "organic heterocyclic fundamental parents" RELATED [ChEBI] is_a: CHEBI:33245 ! organic fundamental parent [Term] id: CHEBI:35568 name: mancude ring namespace: chebi_ontology def: "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds." [] subset: 3_STAR synonym: "mancude rings" RELATED [ChEBI] synonym: "mancude-ring systems" EXACT IUPAC_NAME [IUPAC] synonym: "mancunide-ring systems" RELATED [IUPAC] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:35570 name: mancude organic heterobicyclic parent namespace: chebi_ontology subset: 3_STAR synonym: "mancude organic heterobicyclic parents" RELATED [ChEBI] synonym: "mancude-ring organic heterobicyclic parents" RELATED [ChEBI] is_a: CHEBI:27171 ! organic heterobicyclic compound is_a: CHEBI:35571 ! mancude organic heterocyclic parent [Term] id: CHEBI:35571 name: mancude organic heterocyclic parent namespace: chebi_ontology subset: 3_STAR synonym: "mancude organic heterocyclic parents" RELATED [ChEBI] synonym: "mancude-ring organic heterocyclic parents" RELATED [ChEBI] is_a: CHEBI:35552 ! heterocyclic organic fundamental parent is_a: CHEBI:35573 ! organic mancude parent [Term] id: CHEBI:35573 name: organic mancude parent namespace: chebi_ontology subset: 3_STAR synonym: "organic mancude parents" RELATED [ChEBI] synonym: "organic mancude-ring parents" RELATED [ChEBI] is_a: CHEBI:33245 ! organic fundamental parent is_a: CHEBI:35568 ! mancude ring [Term] id: CHEBI:35584 name: purine namespace: chebi_ontology def: "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines." [] subset: 3_STAR synonym: "purine" EXACT IUPAC_NAME [IUPAC] xref: HMDB:HMDB0001366 xref: KEGG:C15587 xref: MetaCyc:PURINE xref: PMID:12865945 {source="Europe PMC"} xref: PMID:24088627 {source="Europe PMC"} is_a: BFO:0000004 ! independent continuant is_a: CHEBI:26401 ! purines is_a: CHEBI:35570 ! mancude organic heterobicyclic parent relationship: has_role CHEBI:78675 ! fundamental metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H4N4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "120.112" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "120.04360" xsd:string [Term] id: CHEBI:35586 name: 1H-purine namespace: chebi_ontology def: "The 1H-tautomer of purine." [] subset: 3_STAR synonym: "1H-purine" EXACT [ChEBI] xref: Gmelin:2379911 {source="Gmelin"} is_a: CHEBI:35584 ! purine relationship: is_tautomer_of CHEBI:17258 ! 7H-purine relationship: is_tautomer_of CHEBI:35588 ! 3H-purine relationship: is_tautomer_of CHEBI:35589 ! 9H-purine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H4N4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "120.11210" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "120.04360" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1nc2c[nH]cnc2n1" xsd:string [Term] id: CHEBI:35588 name: 3H-purine namespace: chebi_ontology def: "The 3H-tautomer of purine." [] subset: 3_STAR synonym: "3H-purine" EXACT IUPAC_NAME [IUPAC] xref: PMID:6149478 {source="Europe PMC"} xref: PMID:7178185 {source="Europe PMC"} xref: PMID:7296170 {source="Europe PMC"} xref: Reaxys:1210196 {source="Reaxys"} is_a: CHEBI:35584 ! purine relationship: is_tautomer_of CHEBI:17258 ! 7H-purine relationship: is_tautomer_of CHEBI:35586 ! 1H-purine relationship: is_tautomer_of CHEBI:35589 ! 9H-purine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H4N4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "120.11222" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "120.04360" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1nc2cnc[nH]c2n1" xsd:string [Term] id: CHEBI:35589 name: 9H-purine namespace: chebi_ontology def: "The 9H-tautomer of purine." [] subset: 3_STAR synonym: "9H-purine" EXACT IUPAC_NAME [IUPAC] synonym: "9H-purine" EXACT [UniProt] xref: Beilstein:606899 {source="Beilstein"} xref: CAS:120-73-0 {source="NIST Chemistry WebBook"} xref: Gmelin:3120 {source="Gmelin"} xref: Wikipedia:Purine is_a: CHEBI:35584 ! purine relationship: is_tautomer_of CHEBI:17258 ! 7H-purine relationship: is_tautomer_of CHEBI:35586 ! 1H-purine relationship: is_tautomer_of CHEBI:35588 ! 3H-purine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C5H4N4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "120.11222" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "120.04360" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ncc2nc[nH]c2n1" xsd:string [Term] id: CHEBI:35604 name: carbon oxoanion namespace: chebi_ontology def: "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." [] subset: 3_STAR synonym: "carbon oxoanion" EXACT [ChEBI] synonym: "carbon oxoanions" RELATED [ChEBI] synonym: "oxocarbon anion" RELATED [ChEBI] synonym: "oxocarbon anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35605 name: carbon oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "carbon oxoacids" RELATED [ChEBI] synonym: "oxoacids of carbon" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35610 name: antineoplastic agent namespace: chebi_ontology def: "A substance that inhibits or prevents the proliferation of neoplasms." [] subset: 3_STAR synonym: "anticancer agent" RELATED [ChEBI] synonym: "anticancer agents" RELATED [ChEBI] synonym: "antineoplastic" RELATED [ChEBI] synonym: "antineoplastic agents" RELATED [ChEBI] synonym: "cytostatic" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35618 name: aromatic ether namespace: chebi_ontology def: "Any ether in which the oxygen is attached to at least one aryl substituent." [] subset: 3_STAR is_a: CHEBI:25698 ! ether is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:35682 name: naphthol namespace: chebi_ontology def: "A member of the class of naphthols carrying a single hydroxy substituent at C-1 or C-2. A closed class." [] subset: 3_STAR synonym: "hydroxynaphthalene" RELATED [ChEBI] synonym: "naphthalenol" EXACT IUPAC_NAME [IUPAC] synonym: "naphthol" EXACT [IUPAC] xref: CAS:1321-67-1 {source="ChemIDplus"} is_a: CHEBI:25392 ! naphthols relationship: has_parent_hydride CHEBI:16482 ! naphthalene property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H8O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "144.170" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "144.05751" xsd:string [Term] id: CHEBI:35684 name: antiplatyhelmintic drug namespace: chebi_ontology def: "An agent used to treat cestode, trematode, or other flatworm infestations in man or animals." [] subset: 3_STAR synonym: "antiplatyhelmintic agent" RELATED [ChEBI] synonym: "antiplatyhelmintic drugs" RELATED [ChEBI] is_a: CHEBI:35443 ! anthelminthic drug [Term] id: CHEBI:35692 name: dicarboxylic acid namespace: chebi_ontology alt_id: CHEBI:23692 alt_id: CHEBI:36172 alt_id: CHEBI:4501 def: "Any carboxylic acid containing two carboxy groups." [] subset: 3_STAR synonym: "Dicarboxylic acid" EXACT [KEGG_COMPOUND] synonym: "dicarboxylic acids" RELATED [ChEBI] xref: KEGG:C02028 is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35693 ! dicarboxylic acid anion [Term] id: CHEBI:35693 name: dicarboxylic acid anion namespace: chebi_ontology subset: 3_STAR synonym: "dicarboxylic acid anion" EXACT [ChEBI] synonym: "dicarboxylic acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:35692 ! dicarboxylic acid [Term] id: CHEBI:35701 name: ester namespace: chebi_ontology alt_id: CHEBI:23960 alt_id: CHEBI:4859 def: "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." [] subset: 3_STAR synonym: "Ester" EXACT [KEGG_COMPOUND] synonym: "esters" RELATED [ChEBI] xref: KEGG:C00287 xref: Wikipedia:Ester is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35702 name: diethyl ether namespace: chebi_ontology alt_id: CHEBI:23991 alt_id: CHEBI:31565 def: "An ether in which the oxygen atom is linked to two ethyl groups." [] subset: 3_STAR synonym: "1,1'-oxybisethane" RELATED [ChemIDplus] synonym: "1,1'-oxydiethane" EXACT IUPAC_NAME [IUPAC] synonym: "3-oxapentane" RELATED [ChemIDplus] synonym: "Aether" RELATED [ChEBI] synonym: "aether" RELATED [NIST_Chemistry_WebBook] synonym: "aether pro narcosi" RELATED [ChEBI] synonym: "Anesthetic ether" RELATED [KEGG_COMPOUND] synonym: "Diethyl ether" EXACT [KEGG_COMPOUND] synonym: "diethyl oxide" RELATED [ChemIDplus] synonym: "Diethylaether" RELATED [ChEBI] synonym: "Ether" RELATED [KEGG_COMPOUND] synonym: "ethoxyethane" RELATED [ChemIDplus] synonym: "ethyl ether" RELATED [ChemIDplus] synonym: "ethyl oxide" RELATED [ChemIDplus] synonym: "Pronarcol" RELATED [NIST_Chemistry_WebBook] synonym: "R-610" RELATED [ChEBI] xref: Beilstein:1696894 {source="Beilstein"} xref: CAS:60-29-7 {source="NIST Chemistry WebBook"} xref: CAS:60-29-7 {source="ChemIDplus"} xref: CAS:60-29-7 {source="KEGG COMPOUND"} xref: Drug_Central:4417 {source="DrugCentral"} xref: Gmelin:25444 {source="Gmelin"} xref: KEGG:C13240 xref: KEGG:D01772 xref: PMID:24443836 {source="Europe PMC"} xref: Reaxys:1696894 {source="Reaxys"} xref: Wikipedia:Diethyl_ether is_a: BFO:0000004 ! independent continuant is_a: CHEBI:134179 ! volatile organic compound is_a: CHEBI:25698 ! ether is_a: FBcv:0000580 ! ethyl ether equivalent_to: FBcv:0000580 ! ethyl ether relationship: has_role CHEBI:38870 ! inhalation anaesthetic relationship: has_role CHEBI:48355 ! non-polar solvent relationship: has_role CHEBI:78433 ! refrigerant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H10O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RTZKZFJDLAIYFH-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.12160" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.07316" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCOCC" xsd:string [Term] id: CHEBI:35703 name: xenobiotic namespace: chebi_ontology alt_id: CHEBI:10074 alt_id: CHEBI:27333 def: "A xenobiotic (Greek, xenos \"foreign\"; bios \"life\") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." [] subset: 3_STAR synonym: "Xenobiotic" EXACT [KEGG_COMPOUND] synonym: "xenobiotic" EXACT IUPAC_NAME [IUPAC] synonym: "xenobiotic compounds" RELATED [ChEBI] synonym: "xenobiotics" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C06708 xref: Wikipedia:Xenobiotic is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:35705 name: immunosuppressive agent namespace: chebi_ontology def: "An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response." [] subset: 3_STAR synonym: "immunosuppressant" RELATED [ChEBI] synonym: "immunosuppressive agents" RELATED [ChEBI] synonym: "inmunosupresor" RELATED [ChEBI] is_a: CHEBI:50846 ! immunomodulator [Term] id: CHEBI:35715 name: nitro compound namespace: chebi_ontology def: "A compound having a nitro group, -NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied)." [] subset: 3_STAR synonym: "nitro compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_part CHEBI:29785 ! nitro group [Term] id: CHEBI:35757 name: monocarboxylic acid anion namespace: chebi_ontology alt_id: CHEBI:13657 alt_id: CHEBI:25382 alt_id: CHEBI:3407 def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a monocarboxylate" RELATED [UniProt] synonym: "Carboxylate" RELATED [KEGG_COMPOUND] synonym: "Monocarboxylate" RELATED [KEGG_COMPOUND] synonym: "monocarboxylates" RELATED [ChEBI] synonym: "monocarboxylic acid anions" RELATED [ChEBI] xref: KEGG:C00060 is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:25384 ! monocarboxylic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.01000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:35780 name: phosphate ion namespace: chebi_ontology def: "A phosphorus oxoanion that is the conjugate base of phosphoric acid." [] subset: 3_STAR synonym: "phosphate" RELATED [ChEBI] synonym: "phosphate ions" RELATED [ChEBI] synonym: "Pi" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33461 ! phosphorus oxoanion relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:26078 ! phosphoric acid [Term] id: CHEBI:35800 name: nitroso compound namespace: chebi_ontology def: "Compounds having the nitroso group, -NO, attached to carbon, or to another element, most commonly nitrogen or oxygen." [] subset: 3_STAR synonym: "nitroso compounds" RELATED [ChEBI] is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_part CHEBI:35801 ! nitroso group [Term] id: CHEBI:35801 name: nitroso group namespace: chebi_ontology subset: 3_STAR synonym: "-N=O" RELATED [IUPAC] synonym: "nitroso" EXACT IUPAC_NAME [IUPAC] synonym: "O=N-" RELATED [IUPAC] is_a: CHEBI:33246 ! inorganic group is_a: CHEBI:51144 ! nitrogen group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "NO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "30.00614" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "29.99799" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=N*" xsd:string [Term] id: CHEBI:35803 name: nitrosamine namespace: chebi_ontology def: "N-Nitroso amines, compounds of the structure R2NNO. Compounds RNHNO are not ordinarily isolable, but they, too, are nitrosamines. The name is a contraction of N-nitrosoamine and, as such, does not require the N locant." [] subset: 3_STAR synonym: "N-Nitroso amines" RELATED [IUPAC] synonym: "nitrosamines" RELATED [ChEBI] xref: Wikipedia:Nitrosamine is_a: CHEBI:35800 ! nitroso compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "N2OR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.01280" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.00106" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]N([*])N=O" xsd:string [Term] id: CHEBI:35807 name: N-nitrosodimethylamine namespace: chebi_ontology alt_id: CHEBI:21778 alt_id: CHEBI:34874 subset: 3_STAR synonym: "1,1-Dimethyl-2-oxohydrazine" RELATED [NIST_Chemistry_WebBook] synonym: "Dimethylnitrosamine" RELATED [KEGG_COMPOUND] synonym: "Dimethylnitrosoamine" RELATED [ChemIDplus] synonym: "DMN" RELATED [ChemIDplus] synonym: "N,N-Dimethylnitrosamine" RELATED [ChemIDplus] synonym: "N-methyl-N-nitrosomethanamine" EXACT IUPAC_NAME [IUPAC] synonym: "N-Nitrosodimethylamine" EXACT [ChemIDplus] synonym: "N-Nitrosodimethylamine" EXACT [KEGG_COMPOUND] xref: CAS:62-75-9 {source="KEGG COMPOUND"} xref: CAS:62-75-9 {source="ChemIDplus"} xref: CAS:62-75-9 {source="NIST Chemistry WebBook"} xref: KEGG:C14704 xref: PPDB:1645 is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35803 ! nitrosamine is_a: FBcv:0000593 ! N-nitrosodimethylamine equivalent_to: FBcv:0000593 ! N-nitrosodimethylamine relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H6N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H6N2O/c1-4(2)3-5/h1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UMFJAHHVKNCGLG-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.08192" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.04801" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CN(C)N=O" xsd:string [Term] id: CHEBI:35820 name: antiprotozoal drug namespace: chebi_ontology def: "Any antimicrobial drug which is used to treat or prevent protozoal infections." [] subset: 3_STAR synonym: "antiprotozoal agent" RELATED [ChEBI] synonym: "antiprotozoal agents" RELATED [ChEBI] synonym: "antiprotozoal drugs" RELATED [ChEBI] xref: Wikipedia:Antiprotozoal_agent is_a: CHEBI:35442 ! antiparasitic agent is_a: CHEBI:36043 ! antimicrobial drug [Term] id: CHEBI:35875 name: imidazopyrimidine namespace: chebi_ontology subset: 3_STAR synonym: "imidazopyrimidines" RELATED [ChEBI] is_a: CHEBI:27171 ! organic heterobicyclic compound is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:35881 name: pnictogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen hydride" EXACT [ChEBI] synonym: "pnictogen hydrides" RELATED [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33302 ! pnictogen molecular entity [Term] id: CHEBI:35942 name: neurotransmitter agent namespace: chebi_ontology def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." [] subset: 3_STAR synonym: "neurotransmitter agents" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:36016 name: chloroethanes namespace: chebi_ontology def: "A chloroalkane that is ethane in which one or more of the hydrogens is replaced by chlorine." [] subset: 3_STAR is_a: CHEBI:134179 ! volatile organic compound is_a: CHEBI:23128 ! chloroalkane relationship: has_parent_hydride CHEBI:42266 ! ethane [Term] id: CHEBI:36043 name: antimicrobial drug namespace: chebi_ontology def: "A drug used to treat or prevent microbial infections." [] subset: 3_STAR synonym: "antimicrobial drugs" RELATED [ChEBI] is_a: CHEBI:33281 ! antimicrobial agent is_a: CHEBI:35441 ! antiinfective agent [Term] id: CHEBI:36044 name: antiviral drug namespace: chebi_ontology def: "A substance used in the prophylaxis or therapy of virus diseases." [] subset: 3_STAR synonym: "anti-viral drug" RELATED [ChEBI] synonym: "anti-virus drug" RELATED [ChEBI] synonym: "antiviral drugs" RELATED [ChEBI] is_a: CHEBI:22587 ! antiviral agent is_a: CHEBI:36043 ! antimicrobial drug [Term] id: CHEBI:36094 name: organic chloride salt namespace: chebi_ontology subset: 3_STAR synonym: "organic chloride salts" RELATED [ChEBI] is_a: CHEBI:23114 ! chloride salt is_a: CHEBI:51069 ! organic halide salt [Term] id: CHEBI:36141 name: quinone namespace: chebi_ontology alt_id: CHEBI:13684 alt_id: CHEBI:26517 def: "Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included)." [] subset: 3_STAR synonym: "Chinon" RELATED [ChEBI] synonym: "quinone" EXACT [IUPAC] synonym: "quinones" EXACT IUPAC_NAME [IUPAC] synonym: "quinones" RELATED [ChEBI] xref: Wikipedia:Quinone is_a: CHEBI:3992 ! cyclic ketone [Term] id: CHEBI:36233 name: disaccharide namespace: chebi_ontology alt_id: CHEBI:23844 alt_id: CHEBI:4654 def: "A compound in which two monosaccharides are joined by a glycosidic bond." [] subset: 3_STAR synonym: "disacarido" RELATED [ChEBI] synonym: "disacaridos" RELATED [IUPAC] synonym: "Disaccharid" RELATED [ChEBI] synonym: "Disaccharide" EXACT [KEGG_COMPOUND] synonym: "disaccharides" EXACT IUPAC_NAME [IUPAC] synonym: "Disacharid" RELATED [ChEBI] xref: KEGG:C01911 is_a: CHEBI:50699 ! oligosaccharide [Term] id: CHEBI:36336 name: naphthalenesulfonic acid namespace: chebi_ontology subset: 3_STAR synonym: "naphthalenesulfonic acids" RELATED [ChEBI] is_a: CHEBI:25477 ! naphthalenes is_a: CHEBI:33555 ! arenesulfonic acid [Term] id: CHEBI:36338 name: lepton namespace: chebi_ontology def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." [] subset: 3_STAR synonym: "leptons" RELATED [ChEBI] is_a: CHEBI:33233 ! fundamental particle is_a: CHEBI:36340 ! fermion [Term] id: CHEBI:36339 name: baryon namespace: chebi_ontology def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." [] subset: 3_STAR synonym: "baryons" RELATED [ChEBI] is_a: CHEBI:36340 ! fermion is_a: CHEBI:36344 ! hadron [Term] id: CHEBI:36340 name: fermion namespace: chebi_ontology def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." [] subset: 3_STAR synonym: "fermion" EXACT IUPAC_NAME [IUPAC] synonym: "fermions" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36342 name: subatomic particle namespace: chebi_ontology def: "A particle smaller than an atom." [] subset: 3_STAR synonym: "subatomic particles" RELATED [ChEBI] xref: Wikipedia:Subatomic_particle [Term] id: CHEBI:36343 name: composite particle namespace: chebi_ontology def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." [] subset: 3_STAR synonym: "composite particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36344 name: hadron namespace: chebi_ontology def: "Hadron is a subatomic particle which experiences the strong force." [] subset: 3_STAR synonym: "hadrons" RELATED [ChEBI] is_a: CHEBI:36343 ! composite particle [Term] id: CHEBI:36347 name: nuclear particle namespace: chebi_ontology def: "A nucleus or any of its constituents in any of their energy states." [] subset: 3_STAR synonym: "nuclear particle" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36357 name: polyatomic entity namespace: chebi_ontology def: "Any molecular entity consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:24433 ! group [Term] id: CHEBI:36358 name: polyatomic ion namespace: chebi_ontology def: "An ion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:36360 name: phosphorus oxoacids and derivatives namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:26082 ! phosphorus molecular entity [Term] id: CHEBI:36388 name: saturated organic heterocyclic parent namespace: chebi_ontology subset: 3_STAR synonym: "saturated heterocyclic parent hydride" RELATED [ChEBI] synonym: "saturated heterocyclic parent hydrides" RELATED [ChEBI] synonym: "saturated organic heterocyclic parents" RELATED [ChEBI] is_a: CHEBI:35552 ! heterocyclic organic fundamental parent [Term] id: CHEBI:36389 name: saturated organic heteromonocyclic parent namespace: chebi_ontology subset: 3_STAR synonym: "saturated heteromonocyclic parent hydride" RELATED [ChEBI] synonym: "saturated heteromonocyclic parent hydrides" RELATED [ChEBI] synonym: "saturated organic heteromonocyclic parents" RELATED [ChEBI] is_a: CHEBI:25693 ! organic heteromonocyclic compound is_a: CHEBI:36388 ! saturated organic heterocyclic parent [Term] id: CHEBI:36416 name: mancude organic heterotricyclic parent namespace: chebi_ontology subset: 3_STAR synonym: "mancude organic heterotricyclic parents" RELATED [ChEBI] synonym: "mancude-ring organic heterotricyclic parents" RELATED [ChEBI] is_a: CHEBI:26979 ! organic heterotricyclic compound is_a: CHEBI:35571 ! mancude organic heterocyclic parent [Term] id: CHEBI:36420 name: acridine namespace: chebi_ontology def: "A polycyclic heteroarene that is anthracene in which one of the central CH groups is replaced by a nitrogen atom." [] subset: 3_STAR synonym: "10-azaanthracene" RELATED [ChemIDplus] synonym: "2,3,5,6-dibenzopyridine" RELATED [ChemIDplus] synonym: "2,3-benzoquinoline" RELATED [ChemIDplus] synonym: "9-azaanthracene" RELATED [ChemIDplus] synonym: "acridine" EXACT IUPAC_NAME [IUPAC] synonym: "acrydine" RELATED [NIST_Chemistry_WebBook] synonym: "Akridin" RELATED [NIST_Chemistry_WebBook] synonym: "benzo[b]quinoline" RELATED [NIST_Chemistry_WebBook] synonym: "dibenzo[b,e]pyridine" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:120200 {source="Beilstein"} xref: CAS:260-94-6 {source="NIST Chemistry WebBook"} xref: CAS:260-94-6 {source="ChemIDplus"} xref: Gmelin:143403 {source="Gmelin"} xref: PMID:11924543 {source="Europe PMC"} xref: PMID:24416442 {source="Europe PMC"} xref: Reaxys:120200 {source="Reaxys"} xref: Wikipedia:Acridine is_a: BFO:0000004 ! independent continuant is_a: CHEBI:22213 ! acridines is_a: CHEBI:36416 ! mancude organic heterotricyclic parent is_a: CHEBI:38180 ! polycyclic heteroarene relationship: has_role CHEBI:50902 ! genotoxin property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C13H9N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C13H9N/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-9H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DZBUGLKDJFMEHC-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "179.21730" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "179.07350" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ccc2nc3ccccc3cc2c1" xsd:string [Term] id: CHEBI:36586 name: carbonyl compound namespace: chebi_ontology def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." [] subset: 3_STAR synonym: "carbonyl compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36587 ! organic oxo compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23019 ! carbonyl group [Term] id: CHEBI:36587 name: organic oxo compound namespace: chebi_ontology def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." [] subset: 3_STAR synonym: "organic oxo compounds" RELATED [ChEBI] synonym: "oxo compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:72695 ! organic molecule relationship: has_part CHEBI:46629 ! oxo group [Term] id: CHEBI:36683 name: organochlorine compound namespace: chebi_ontology def: "An organochlorine compound is a compound containing at least one carbon-chlorine bond." [] subset: 3_STAR synonym: "an organochlorine molecule" RELATED [UniProt] synonym: "chloroorganic compounds" RELATED [ChEBI] synonym: "chlororganische Verbindungen" RELATED [ChEBI] synonym: "organochloride" RELATED [ChEBI] synonym: "organochloride compound" RELATED [ChEBI] synonym: "organochloride compounds" RELATED [ChEBI] synonym: "organochlorides" RELATED [ChEBI] synonym: "organochlorine compound" EXACT [ChEBI] synonym: "organochlorine compounds" RELATED [ChEBI] xref: MetaCyc:Chlorides xref: Wikipedia:Organochloride is_a: CHEBI:17792 ! organohalogen compound is_a: CHEBI:23117 ! chlorine molecular entity property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "ClR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "35.453" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "34.96885" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*Cl" xsd:string [Term] id: CHEBI:36688 name: heterotricyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "heterotricyclic compound" EXACT [ChEBI] synonym: "heterotricyclic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "heterotricyclic compounds" RELATED [ChEBI] is_a: CHEBI:33671 ! heteropolycyclic compound [Term] id: CHEBI:36785 name: carbobicyclic compound namespace: chebi_ontology def: "A bicyclic compound in which all the ring atoms are carbon." [] subset: 3_STAR synonym: "carbobicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33636 ! bicyclic compound is_a: CHEBI:35294 ! carbopolycyclic compound [Term] id: CHEBI:36830 name: monoanion namespace: chebi_ontology subset: 3_STAR synonym: "monoanions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string [Term] id: CHEBI:36892 name: elemental fluorine namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:33434 ! elemental halogen [Term] id: CHEBI:36895 name: monoatomic fluorine namespace: chebi_ontology subset: 3_STAR synonym: "atomic fluorine" RELATED [ChEBI] is_a: CHEBI:36892 ! elemental fluorine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "F" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "18.998" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.99840" xsd:string [Term] id: CHEBI:36914 name: inorganic ion namespace: chebi_ontology subset: 3_STAR synonym: "inorganic ions" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:24870 ! ion is_a: FBcv:0000553 ! inorganic compound [Term] id: CHEBI:36915 name: inorganic cation namespace: chebi_ontology subset: 3_STAR synonym: "inorganic cations" RELATED [ChEBI] is_a: CHEBI:36914 ! inorganic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:36916 name: cation namespace: chebi_ontology alt_id: CHEBI:23058 alt_id: CHEBI:3473 def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." [] subset: 3_STAR synonym: "Cation" EXACT [KEGG_COMPOUND] synonym: "cation" EXACT IUPAC_NAME [IUPAC] synonym: "cation" EXACT [ChEBI] synonym: "cationes" RELATED [ChEBI] synonym: "cations" RELATED [ChEBI] synonym: "Kation" RELATED [ChEBI] synonym: "Kationen" RELATED [ChEBI] xref: KEGG:C01373 is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36961 name: chalcocarbonic acid namespace: chebi_ontology subset: 3_STAR synonym: "chalcocarbonic acid" EXACT [ChEBI] synonym: "chalcocarbonic acids" EXACT IUPAC_NAME [IUPAC] synonym: "chalcocarbonic acids" RELATED [ChEBI] is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:36962 name: organochalcogen compound namespace: chebi_ontology def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." [] subset: 3_STAR synonym: "organochalcogen compound" EXACT [ChEBI] synonym: "organochalcogen compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36963 name: organooxygen compound namespace: chebi_ontology def: "An organochalcogen compound containing at least one carbon-oxygen bond." [] subset: 3_STAR synonym: "organooxygen compound" EXACT [ChEBI] synonym: "organooxygen compounds" RELATED [ChEBI] xref: PMID:17586126 {source="Europe PMC"} is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:37022 name: amino-acid anion namespace: chebi_ontology subset: 3_STAR synonym: "amino acid anions" RELATED [ChEBI] synonym: "amino-acid anion" EXACT [ChEBI] synonym: "amino-acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion is_a: CHEBI:35352 ! organonitrogen compound relationship: is_conjugate_base_of CHEBI:33709 ! amino acid [Term] id: CHEBI:37141 name: organobromine compound namespace: chebi_ontology def: "A compound containing at least one carbon-bromine bond." [] subset: 3_STAR synonym: "an organobromine molecule" RELATED [UniProt] synonym: "bromoorganic compound" RELATED [ChEBI] synonym: "organobromide" RELATED [ChEBI] synonym: "organobromide compound" RELATED [ChEBI] synonym: "organobromide compounds" RELATED [ChEBI] synonym: "organobromides" RELATED [ChEBI] synonym: "organobromine compound" EXACT [ChEBI] synonym: "organobromine compounds" RELATED [ChEBI] xref: MetaCyc:Bromide xref: Wikipedia:Organobromine_compound is_a: CHEBI:17792 ! organohalogen compound is_a: CHEBI:22928 ! bromine molecular entity property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "BrR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "79.904" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "78.91834" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*Br" xsd:string [Term] id: CHEBI:37143 name: organofluorine compound namespace: chebi_ontology def: "An organofluorine compound is a compound containing at least one carbon-fluorine bond." [] subset: 3_STAR synonym: "fluoroorganic compound" RELATED [ChEBI] synonym: "fluoroorganic compounds" RELATED [ChEBI] synonym: "fluoroorganics" RELATED [ChEBI] synonym: "fluororganische Verbindungen" RELATED [ChEBI] synonym: "organofluorine compound" EXACT [ChEBI] synonym: "organofluorine compounds" RELATED [ChEBI] xref: MetaCyc:Fluorides is_a: CHEBI:17792 ! organohalogen compound is_a: CHEBI:24062 ! fluorine molecular entity property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "FR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "18.998" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.99840" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*F" xsd:string [Term] id: CHEBI:37175 name: organic hydride namespace: chebi_ontology subset: 3_STAR synonym: "organic hydrides" RELATED [ChEBI] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37176 name: mononuclear parent hydride namespace: chebi_ontology subset: 3_STAR synonym: "mononuclear hydride" RELATED [ChEBI] synonym: "mononuclear hydrides" RELATED [IUPAC] synonym: "mononuclear parent hydrides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37246 name: elemental sodium namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:26712 ! sodium molecular entity [Term] id: CHEBI:37334 name: diagnostic imaging agent namespace: chebi_ontology def: "A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease." [] subset: 3_STAR is_a: CHEBI:33295 ! diagnostic agent [Term] id: CHEBI:37335 name: MRI contrast agent namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:37334 ! diagnostic imaging agent [Term] id: CHEBI:37404 name: elemental copper namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:23377 ! copper molecular entity [Term] id: CHEBI:37407 name: cyclic ether namespace: chebi_ontology alt_id: CHEBI:37406 def: "Any ether in which the oxygen atom forms part of a ring." [] subset: 3_STAR synonym: "cyclic ether" EXACT [IUPAC] synonym: "cyclic ethers" EXACT IUPAC_NAME [IUPAC] synonym: "cyclic ethers" RELATED [ChEBI] synonym: "epoxy compounds" EXACT IUPAC_NAME [IUPAC] synonym: "epoxy compounds" RELATED [ChEBI] is_a: CHEBI:25698 ! ether is_a: CHEBI:38104 ! oxacycle [Term] id: CHEBI:37445 name: folic acids namespace: chebi_ontology alt_id: CHEBI:24074 alt_id: CHEBI:24076 def: "A group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid units." [] subset: 3_STAR synonym: "folate" RELATED [ChEBI] synonym: "folates" EXACT IUPAC_NAME [IUPAC] synonym: "folates" RELATED [ChEBI] is_a: CHEBI:176842 ! vitamin B9 is_a: CHEBI:26375 ! pterins is_a: CHEBI:83982 ! L-glutamic acid derivative relationship: is_conjugate_acid_of CHEBI:67011 ! folates [Term] id: CHEBI:37527 name: acid namespace: chebi_ontology alt_id: CHEBI:13800 alt_id: CHEBI:13801 alt_id: CHEBI:22209 alt_id: CHEBI:2426 def: "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." [] subset: 3_STAR synonym: "Acid" EXACT [KEGG_COMPOUND] synonym: "acid" EXACT IUPAC_NAME [IUPAC] synonym: "acide" RELATED [IUPAC] synonym: "acido" RELATED [ChEBI] synonym: "acids" RELATED [ChEBI] synonym: "Saeure" RELATED [ChEBI] synonym: "Saeuren" RELATED [ChEBI] xref: KEGG:C00174 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:37577 name: heteroatomic molecular entity namespace: chebi_ontology def: "A molecular entity consisting of two or more chemical elements." [] subset: 3_STAR synonym: "chemical compound" RELATED [ChEBI] synonym: "heteroatomic molecular entities" RELATED [ChEBI] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:37578 name: halide namespace: chebi_ontology def: "Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements." [] subset: 3_STAR synonym: "halides" RELATED [ChEBI] xref: Wikipedia:Halide is_a: CHEBI:24471 ! halogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:37594 name: N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine namespace: chebi_ontology subset: 3_STAR synonym: "N-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)-N-ethylpropane-1,3-diamine" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:498343 {source="Beilstein"} is_a: CHEBI:22213 ! acridines property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C21H25Cl2N3O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C21H25Cl2N3O/c1-3-26(12-9-22)11-4-10-24-21-17-7-5-15(23)13-20(17)25-19-8-6-16(27-2)14-18(19)21/h5-8,13-14H,3-4,9-12H2,1-2H3,(H,24,25)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OIFINQAUHKZSBV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "406.34822" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "405.13747" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(CCCl)CCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12" xsd:string [Term] id: CHEBI:37595 name: quinacrine mustard namespace: chebi_ontology alt_id: CHEBI:47635 subset: 3_STAR synonym: "N(1),N(1)-bis(2-chloroethyl)-N(4)-(6-chloro-2-methoxyacridin-9-yl)pentane-1,4-diamine" EXACT IUPAC_NAME [IUPAC] synonym: "quinacrine mustard" EXACT [ChemIDplus] xref: Beilstein:56337 {source="Beilstein"} xref: CAS:64046-79-3 {source="ChemIDplus"} is_a: CHEBI:37598 ! nitrogen mustard is_a: CHEBI:51803 ! aminoacridines is_a: FBcv:0000541 ! intercalating agent is_a: FBcv:0000543 ! quinacrine mustard is_a: FBcv:0000813 ! nitrogen mustard equivalent_to: FBcv:0000543 ! quinacrine mustard relationship: has_functional_parent CHEBI:8711 ! quinacrine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C23H28Cl3N3O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C23H28Cl3N3O/c1-16(4-3-11-29(12-9-24)13-10-25)27-23-19-7-5-17(26)14-22(19)28-21-8-6-18(30-2)15-20(21)23/h5-8,14-16H,3-4,9-13H2,1-2H3,(H,27,28)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "UKOBAUFLOGFCMV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "468.84614" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "467.12980" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COc1ccc2nc3cc(Cl)ccc3c(NC(C)CCCN(CCCl)CCCl)c2c1" xsd:string [Term] id: CHEBI:37598 name: nitrogen mustard namespace: chebi_ontology def: "Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR." [] subset: 3_STAR synonym: "nitrogen mustard compound" RELATED [ChEBI] synonym: "nitrogen mustard compounds" RELATED [ChEBI] synonym: "nitrogen mustards" EXACT IUPAC_NAME [IUPAC] synonym: "nitrogen mustards" RELATED [ChEBI] xref: Wikipedia:Nitrogen_mustard is_a: CHEBI:35352 ! organonitrogen compound is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000813 ! nitrogen mustard equivalent_to: FBcv:0000813 ! nitrogen mustard relationship: has_role CHEBI:22333 ! alkylating agent [Term] id: CHEBI:37622 name: carboxamide namespace: chebi_ontology alt_id: CHEBI:35354 alt_id: CHEBI:35355 def: "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." [] subset: 3_STAR synonym: "carboxamides" EXACT IUPAC_NAME [IUPAC] synonym: "carboxamides" RELATED [ChEBI] synonym: "primary carboxamide" RELATED [ChEBI] is_a: CHEBI:33256 ! primary amide is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23004 ! carbamoyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CNOR3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "42.01680" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "41.99799" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)N([*])[*]" xsd:string [Term] id: CHEBI:37699 name: protein kinase inhibitor namespace: chebi_ontology def: "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases." [] subset: 3_STAR synonym: "protein kinase inhibitors" RELATED [ChEBI] is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor [Term] id: CHEBI:37808 name: butane namespace: chebi_ontology alt_id: CHEBI:22945 alt_id: CHEBI:25462 alt_id: CHEBI:44430 def: "A straight chain alkane composed of 4 carbon atoms." [] subset: 3_STAR synonym: "butane" EXACT IUPAC_NAME [IUPAC] synonym: "butane" EXACT [UniProt] synonym: "E 943a" RELATED [ChEBI] synonym: "E-943a" RELATED [ChEBI] synonym: "E943a" RELATED [ChEBI] synonym: "n-Butan" RELATED [ChEBI] synonym: "N-BUTANE" RELATED [PDBeChem] synonym: "n-butane" RELATED [NIST_Chemistry_WebBook] synonym: "n-C4H10" RELATED [NIST_Chemistry_WebBook] synonym: "R-600" RELATED [ChEBI] xref: Beilstein:969129 {source="Beilstein"} xref: CAS:106-97-8 {source="ChemIDplus"} xref: CAS:106-97-8 {source="NIST Chemistry WebBook"} xref: Gmelin:1148 {source="Gmelin"} xref: PDBeChem:NBU xref: PMID:24179026 {source="Europe PMC"} xref: Reaxys:969129 {source="Reaxys"} xref: Wikipedia:Butane is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:18310 ! alkane relationship: has_role CHEBI:78017 ! food propellant relationship: has_role CHEBI:78433 ! refrigerant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H10" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H10/c1-3-4-2/h3-4H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IJDNQMDRQITEOD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "58.12220" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "58.07825" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCCC" xsd:string [Term] id: CHEBI:37826 name: sulfuric acid derivative namespace: chebi_ontology subset: 3_STAR synonym: "sulfuric acid derivative" EXACT [ChEBI] synonym: "sulfuric acid derivatives" RELATED [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative relationship: has_functional_parent CHEBI:26836 ! sulfuric acid [Term] id: CHEBI:37838 name: carboacyl group namespace: chebi_ontology def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "carboacyl groups" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl group" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl groups" RELATED [IUPAC] is_a: CHEBI:22221 ! acyl group relationship: is_substituent_group_from CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:37949 name: azacycloalkane namespace: chebi_ontology subset: 3_STAR synonym: "azacycloalkanes" RELATED [ChEBI] is_a: CHEBI:25693 ! organic heteromonocyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:37958 name: dye namespace: chebi_ontology subset: 3_STAR synonym: "colorante" RELATED [ChEBI] synonym: "colorantes" RELATED [ChEBI] synonym: "dyes" RELATED [ChEBI] synonym: "Farbstoff" RELATED [ChEBI] synonym: "Farbstoffe" RELATED [ChEBI] synonym: "teinture" RELATED [ChEBI] synonym: "teintures" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:37972 name: phosphorus-32 atom namespace: chebi_ontology def: "The radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days." [] subset: 3_STAR synonym: "(32)15P" RELATED [IUPAC] synonym: "(32)P" RELATED [IUPAC] synonym: "Phosphorus, isotope of mass 32" RELATED [KEGG_COMPOUND] synonym: "phosphorus, isotope of mass 32" RELATED [ChemIDplus] synonym: "phosphorus-32" EXACT IUPAC_NAME [IUPAC] synonym: "phosphorus-32" RELATED [ChEBI] xref: CAS:14596-37-3 {source="KEGG COMPOUND"} xref: CAS:14596-37-3 {source="ChemIDplus"} xref: KEGG:C19162 is_a: CHEBI:28659 ! phosphorus atom is_a: FBcv:0000510 ! 32P equivalent_to: FBcv:0000510 ! 32P property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "[32P]" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/P/i1+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OAICVXFJPJFONN-OUBTZVSYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "31.974" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.97391" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[32P]" xsd:string [Term] id: CHEBI:38032 name: carbotricyclic compound namespace: chebi_ontology def: "A carbopolyclic compound comprising of three carbocyclic rings." [] subset: 3_STAR synonym: "carbotricyclic compounds" RELATED [ChEBI] is_a: CHEBI:35294 ! carbopolycyclic compound is_a: CHEBI:51959 ! organic tricyclic compound [Term] id: CHEBI:38034 name: aminonaphthalene namespace: chebi_ontology subset: 3_STAR synonym: "aminonaphthalenes" RELATED [ChEBI] is_a: CHEBI:25477 ! naphthalenes is_a: CHEBI:33860 ! aromatic amine [Term] id: CHEBI:38037 name: methanesulfonate salt namespace: chebi_ontology subset: 3_STAR synonym: "mesylate salt" RELATED [ChEBI] synonym: "mesylate salts" RELATED [ChEBI] synonym: "methanesulfonate salts" RELATED [ChEBI] is_a: CHEBI:48544 ! methanesulfonates is_a: CHEBI:64382 ! organosulfonate salt [Term] id: CHEBI:38068 name: antimalarial namespace: chebi_ontology def: "A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human." [] subset: 3_STAR synonym: "antimalarials" RELATED [ChEBI] is_a: CHEBI:64915 ! antiplasmodial drug [Term] id: CHEBI:38101 name: organonitrogen heterocyclic compound namespace: chebi_ontology def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." [] subset: 3_STAR synonym: "heterocyclic organonitrogen compounds" RELATED [ChEBI] synonym: "organonitrogen heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:38102 name: triazines namespace: chebi_ontology def: "Compounds based on a triazine skeleton." [] subset: 3_STAR is_a: CHEBI:25693 ! organic heteromonocyclic compound is_a: CHEBI:50893 ! azaarene [Term] id: CHEBI:38104 name: oxacycle namespace: chebi_ontology def: "Any organic heterocyclic compound containing at least one ring oxygen atom." [] subset: 3_STAR synonym: "heterocyclic organooxygen compounds" RELATED [ChEBI] synonym: "organooxygen heterocyclic compounds" RELATED [ChEBI] synonym: "oxacycles" RELATED [ChEBI] xref: PMID:17134300 {source="Europe PMC"} is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:38106 name: organosulfur heterocyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "heterocyclic organosulfur compounds" RELATED [ChEBI] synonym: "organosulfur heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33261 ! organosulfur compound [Term] id: CHEBI:38163 name: organic heterotetracyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic heterotetracyclic compounds" RELATED [ChEBI] is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:38166 name: organic heteropolycyclic compound namespace: chebi_ontology alt_id: CHEBI:25429 alt_id: CHEBI:38075 subset: 3_STAR synonym: "organic heteropolycyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33671 ! heteropolycyclic compound [Term] id: CHEBI:38175 name: triamino-1,3,5-triazine namespace: chebi_ontology subset: 3_STAR synonym: "triamino-1,3,5-triazines" RELATED [ChEBI] is_a: CHEBI:26588 ! 1,3,5-triazines [Term] id: CHEBI:38180 name: polycyclic heteroarene namespace: chebi_ontology subset: 3_STAR synonym: "polycyclic heteroarenes" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene [Term] id: CHEBI:38234 name: DNA polymerase inhibitor namespace: chebi_ontology def: "Any inhibitor of a DNA polymerase." [] subset: 3_STAR is_a: CHEBI:76815 ! EC 2.7.7.* (nucleotidyltransferase) inhibitor [Term] id: CHEBI:38303 name: azirinopyrroloindole namespace: chebi_ontology subset: 3_STAR synonym: "azirinopyrroloindoles" RELATED [ChEBI] is_a: CHEBI:38101 ! organonitrogen heterocyclic compound is_a: CHEBI:38163 ! organic heterotetracyclic compound [Term] id: CHEBI:38313 name: diazines namespace: chebi_ontology def: "Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure)." [] subset: 3_STAR is_a: CHEBI:25693 ! organic heteromonocyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:38323 name: cholinergic drug namespace: chebi_ontology def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." [] subset: 3_STAR synonym: "cholinergic agent" RELATED [ChEBI] synonym: "cholinergic drugs" RELATED [ChEBI] synonym: "cholinomimetic" RELATED [ChEBI] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38337 name: pyrimidone namespace: chebi_ontology def: "A pyrimidine carrying one or more oxo substituents." [] subset: 3_STAR synonym: "pyrimidones" RELATED [ChEBI] is_a: CHEBI:39447 ! pyrimidines [Term] id: CHEBI:38443 name: 1-benzopyran namespace: chebi_ontology subset: 3_STAR synonym: "1-benzopyrans" RELATED [ChEBI] is_a: CHEBI:22727 ! benzopyran [Term] id: CHEBI:38517 name: benzophenanthridine alkaloid namespace: chebi_ontology def: "A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family." [] subset: 3_STAR synonym: "benzophenanthridine alkaloids" RELATED [ChEBI] is_a: CHEBI:24921 ! isoquinoline alkaloid is_a: CHEBI:38518 ! benzophenanthridine [Term] id: CHEBI:38518 name: benzophenanthridine namespace: chebi_ontology subset: 3_STAR synonym: "benzophenanthridines" RELATED [ChEBI] is_a: CHEBI:38101 ! organonitrogen heterocyclic compound is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:38632 name: membrane transport modulator namespace: chebi_ontology def: "Any agent that affects the transport of molecular entities across a biological membrane." [] subset: 3_STAR synonym: "membrane transport modulators" RELATED [ChEBI] is_a: CHEBI:52208 ! biophysical role [Term] id: CHEBI:38672 name: flavans namespace: chebi_ontology def: "Any flavonoid with a 3,4-dihydro-2-aryl-2H-1-benzopyran skeleton and its substituted derivatives." [] subset: 3_STAR is_a: CHEBI:26004 ! phenylpropanoid is_a: CHEBI:38443 ! 1-benzopyran is_a: CHEBI:47916 ! flavonoid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C15OR14" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "196.160" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "195.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]c1c([*])c([*])c(c([*])c1[*])C1([*])Oc2c([*])c([*])c([*])c([*])c2C([*])([*])C1([*])[*]" xsd:string [Term] id: CHEBI:38702 name: inorganic sodium salt namespace: chebi_ontology subset: 3_STAR synonym: "inorganic sodium salts" RELATED [ChEBI] is_a: CHEBI:24839 ! inorganic salt is_a: CHEBI:26714 ! sodium salt [Term] id: CHEBI:38716 name: carboxylic acid dianion namespace: chebi_ontology def: "Any dianion containing at least one carboxy group." [] subset: 3_STAR synonym: "carboxylic acid dianion" EXACT [ChEBI] synonym: "carboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion [Term] id: CHEBI:38738 name: monomethoxyflavanone namespace: chebi_ontology def: "Any methoxyflavanone that is flavanone substituted by a methoxy group." [] subset: 3_STAR synonym: "monomethoxyflavanones" RELATED [ChEBI] is_a: CHEBI:25240 ! methoxyflavanone [Term] id: CHEBI:38739 name: trihydroxyflavanone namespace: chebi_ontology def: "A hydroxyflavanone carrying three hydroxy substituents." [] subset: 3_STAR synonym: "trihydroxyflavanones" RELATED [ChEBI] is_a: CHEBI:24697 ! hydroxyflavanone [Term] id: CHEBI:38749 name: dihydroxyflavanone namespace: chebi_ontology def: "Any hydroxyflavanone carrying two hydroxy substituents." [] subset: 3_STAR synonym: "dihydroxyflavanones" RELATED [ChEBI] is_a: CHEBI:24697 ! hydroxyflavanone [Term] id: CHEBI:38780 name: N-nitro compound namespace: chebi_ontology def: "A compound having the nitro group (-NO2) attached to a nitrogen atom." [] subset: 3_STAR synonym: "N-nitro compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:35715 ! nitro compound [Term] id: CHEBI:38793 name: pteroate namespace: chebi_ontology alt_id: CHEBI:37074 subset: 3_STAR is_a: CHEBI:38796 ! pteroates relationship: is_conjugate_base_of CHEBI:38794 ! pteroic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C14H11N6O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "311.276" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "311.08926" xsd:string [Term] id: CHEBI:38794 name: pteroic acid namespace: chebi_ontology alt_id: CHEBI:26378 subset: 3_STAR synonym: "Pteroic acid" EXACT [ChemIDplus] synonym: "Pteroinsaeure" RELATED [ChEBI] xref: CAS:119-24-4 {source="ChemIDplus"} xref: DrugBank:DB04196 is_a: CHEBI:38795 ! pteroic acids relationship: is_conjugate_acid_of CHEBI:38793 ! pteroate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C14H12N6O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "312.284" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "312.09709" xsd:string [Term] id: CHEBI:38795 name: pteroic acids namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:25384 ! monocarboxylic acid is_a: CHEBI:26375 ! pterins [Term] id: CHEBI:38796 name: pteroates namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:22494 ! aminobenzoate [Term] id: CHEBI:38808 name: calcium channel modulator namespace: chebi_ontology def: "A membrane transport modulator that is able to regulate intracellular calcium levels." [] subset: 3_STAR synonym: "calcium channel modulators" RELATED [ChEBI] is_a: CHEBI:38632 ! membrane transport modulator [Term] id: CHEBI:38809 name: ryanodine receptor modulator namespace: chebi_ontology subset: 3_STAR synonym: "ryanodine receptor modulators" RELATED [ChEBI] synonym: "ryanodine-sensitive calcium channel modulator" RELATED [ChEBI] synonym: "ryanodine-sensitive calcium-release channel modulator" RELATED [ChEBI] synonym: "RyR modulator" RELATED [ChEBI] is_a: CHEBI:38808 ! calcium channel modulator [Term] id: CHEBI:38867 name: anaesthetic namespace: chebi_ontology def: "Substance which produces loss of feeling or sensation." [] subset: 3_STAR synonym: "anaesthetic" EXACT IUPAC_NAME [IUPAC] synonym: "anaesthetics" RELATED [ChEBI] synonym: "Anaesthetika" RELATED [ChEBI] synonym: "Anaesthetikum" RELATED [ChEBI] synonym: "anesthetic agent" RELATED [ChEBI] synonym: "anesthetic drug" RELATED [ChEBI] synonym: "anesthetics" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:38869 name: general anaesthetic namespace: chebi_ontology def: "Substance that produces loss of consciousness." [] subset: 3_STAR synonym: "Allgemeinanaesthetika" RELATED [ChEBI] synonym: "Allgemeinanaesthetikum" RELATED [ChEBI] synonym: "general anaesthetic" EXACT IUPAC_NAME [IUPAC] synonym: "general anaesthetics" RELATED [ChEBI] synonym: "general anesthetics" RELATED [ChEBI] is_a: CHEBI:38867 ! anaesthetic [Term] id: CHEBI:38870 name: inhalation anaesthetic namespace: chebi_ontology subset: 3_STAR synonym: "anesthetic gases" RELATED [ChEBI] synonym: "inhalation anesthetics" RELATED [ChEBI] synonym: "Inhalationsanaesthetika" RELATED [ChEBI] synonym: "Inhalationsanaesthetikum" RELATED [ChEBI] synonym: "Inhalationsnarkotika" RELATED [ChEBI] synonym: "Inhalationsnarkotikum" RELATED [ChEBI] is_a: CHEBI:38869 ! general anaesthetic [Term] id: CHEBI:38941 name: schistosomicide drug namespace: chebi_ontology def: "Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma." [] subset: 3_STAR synonym: "antischistosoma" RELATED [ChEBI] synonym: "antischistosomal drug" RELATED [ChEBI] synonym: "schistosomicide" RELATED [ChEBI] synonym: "schistosomicide drugs" RELATED [ChEBI] synonym: "schistosomicides" RELATED [ChEBI] is_a: CHEBI:35684 ! antiplatyhelmintic drug [Term] id: CHEBI:38975 name: methylbenzene namespace: chebi_ontology def: "Any alkylbenzene that is benzene substituted with one or more methyl groups." [] subset: 3_STAR synonym: "methylbenzenes" RELATED [ChEBI] is_a: CHEBI:38976 ! alkylbenzene [Term] id: CHEBI:38976 name: alkylbenzene namespace: chebi_ontology def: "A monocyclic arene that is benzene substituted with one or more alkyl groups." [] subset: 3_STAR synonym: "alkylbenzene" EXACT [ChEBI] synonym: "alkylbenzenes" RELATED [ChEBI] synonym: "Alkylbenzol" RELATED [ChEBI] is_a: CHEBI:22712 ! benzenes is_a: CHEBI:33847 ! monocyclic arene relationship: has_parent_hydride CHEBI:16716 ! benzene [Term] id: CHEBI:39087 name: sulfurous acid derivative namespace: chebi_ontology def: "Any sulfur oxoacid derivative derived from sulfurous acid." [] subset: 3_STAR synonym: "sulfurous acid derivative" EXACT [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative [Term] id: CHEBI:39141 name: Bronsted acid namespace: chebi_ontology def: "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." [] subset: 3_STAR synonym: "acide de Bronsted" RELATED [IUPAC] synonym: "Bronsted acid" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Saeure" RELATED [ChEBI] synonym: "donneur d'hydron" RELATED [IUPAC] synonym: "hydron donor" RELATED [IUPAC] is_a: CHEBI:17891 ! donor is_a: CHEBI:37527 ! acid [Term] id: CHEBI:39142 name: Bronsted base namespace: chebi_ontology def: "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." [] subset: 3_STAR synonym: "accepteur d'hydron" RELATED [IUPAC] synonym: "base de Bronsted" RELATED [IUPAC] synonym: "Bronsted base" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Base" RELATED [ChEBI] synonym: "hydron acceptor" RELATED [IUPAC] is_a: CHEBI:15339 ! acceptor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39144 name: Lewis base namespace: chebi_ontology def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." [] subset: 3_STAR synonym: "base de Lewis" RELATED [IUPAC] synonym: "donneur d'une paire d'electrons" RELATED [ChEBI] synonym: "electron donor" RELATED [ChEBI] synonym: "Lewis base" EXACT IUPAC_NAME [IUPAC] synonym: "Lewis-Base" RELATED [ChEBI] is_a: CHEBI:17891 ! donor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39179 name: nitroguanidine namespace: chebi_ontology def: "An N-nitro compound that is guanidine in which one of the hydrogens is replaced by a nitro group. It can exist in distinct tautomeric forms, as 1-nitroguanidine (a nitroimine) or 2-nitroguanidine (a nitroamine); in both solid and in solution, the nitroimine form predominates." [] subset: 3_STAR synonym: "nitroguanidine" EXACT IUPAC_NAME [IUPAC] synonym: "picrite" RELATED [NIST_Chemistry_WebBook] xref: CAS:556-88-7 {source="ChemIDplus"} xref: CAS:556-88-7 {source="NIST Chemistry WebBook"} xref: Wikipedia:Nitroguanidine is_a: BFO:0000004 ! independent continuant is_a: CHEBI:38780 ! N-nitro compound relationship: has_functional_parent CHEBI:42820 ! guanidine relationship: has_functional_parent CHEBI:616459 ! carbamimidoylazanium relationship: has_role CHEBI:63490 ! explosive property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH4N4O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "104.068" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "104.03343" xsd:string [Term] id: CHEBI:39201 name: phenazines namespace: chebi_ontology def: "Any organonitrogen heterocyclic compound based on a phenazine skeleton and derivatives." [] subset: 3_STAR is_a: CHEBI:26979 ! organic heterotricyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:39206 name: dibenzopyridine namespace: chebi_ontology subset: 3_STAR synonym: "dibenzopyridines" RELATED [ChEBI] is_a: CHEBI:26979 ! organic heterotricyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:39276 name: fumigant namespace: chebi_ontology def: "A volatile or volatilizable chemical compound utilized for control of pests in buildings, soil, grain, as well as during processing of goods to be imported or exported to prevent transfer of exotic organisms." [] subset: 3_STAR synonym: "fumigant pesticide" RELATED [ChEBI] synonym: "fumigants" RELATED [ChEBI] xref: Wikipedia:Fumigation is_a: CHEBI:25944 ! pesticide [Term] id: CHEBI:39418 name: straight-chain saturated fatty acid namespace: chebi_ontology def: "Any saturated fatty acid lacking a side-chain." [] subset: 3_STAR synonym: "straight-chain saturated fatty acid" EXACT [ChEBI] synonym: "straight-chain saturated fatty acids" RELATED [ChEBI] xref: PMID:15644336 {source="Europe PMC"} is_a: CHEBI:26607 ! saturated fatty acid is_a: CHEBI:59202 ! straight-chain fatty acid relationship: is_conjugate_acid_of CHEBI:58954 ! straight-chain saturated fatty acid anion [Term] id: CHEBI:39446 name: pyrimidine ribonucleosides namespace: chebi_ontology alt_id: CHEBI:13784 alt_id: CHEBI:26445 alt_id: CHEBI:7263 subset: 3_STAR is_a: CHEBI:18254 ! ribonucleoside is_a: CHEBI:26440 ! pyrimidine nucleoside [Term] id: CHEBI:39447 name: pyrimidines namespace: chebi_ontology alt_id: CHEBI:13681 alt_id: CHEBI:26448 def: "Any compound having a pyrimidine as part of its structure." [] subset: 3_STAR is_a: CHEBI:38313 ! diazines [Term] id: CHEBI:39745 name: dihydrogenphosphate namespace: chebi_ontology alt_id: CHEBI:29137 alt_id: CHEBI:39739 def: "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." [] subset: 3_STAR synonym: "[PO2(OH)2](-)" RELATED [IUPAC] synonym: "dihydrogen(tetraoxidophosphate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydrogenphosphate" EXACT IUPAC_NAME [IUPAC] synonym: "DIHYDROGENPHOSPHATE ION" RELATED [PDBeChem] synonym: "dihydrogentetraoxophosphate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidodioxidophosphate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "H2PO4(-)" RELATED [IUPAC] xref: DrugBank:DB02831 xref: Gmelin:1999 {source="Gmelin"} xref: PDBeChem:2HP is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:43474 ! hydrogenphosphate relationship: is_conjugate_base_of CHEBI:26078 ! phosphoric acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.98724" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96962" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP([O-])(=O)O[H]" xsd:string [Term] id: CHEBI:3992 name: cyclic ketone namespace: chebi_ontology subset: 3_STAR synonym: "Cyclic ketone" EXACT [KEGG_COMPOUND] synonym: "cyclic ketones" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C02019 is_a: CHEBI:17087 ! ketone [Term] id: CHEBI:41189 name: butane-1,4-diol namespace: chebi_ontology def: "A butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. A colourless, water-miscible, viscous liquid at room temperature (m.p. 16degreeC) with a high boiling point (230degreeC), it is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF)." [] subset: 3_STAR synonym: "1,4-BD" RELATED [ChemIDplus] synonym: "1,4-BUTANEDIOL" RELATED [PDBeChem] synonym: "1,4-butylene glycol" RELATED [ChemIDplus] synonym: "1,4-dihydroxybutane" RELATED [ChemIDplus] synonym: "1,4-tetramethylene glycol" RELATED [ChemIDplus] synonym: "butane-1,4-diol" EXACT IUPAC_NAME [IUPAC] synonym: "HO(CH2)4OH" RELATED [ChEBI] synonym: "HOCH2CH2CH2CH2OH" RELATED [ChEBI] synonym: "tetramethylene 1,4-diol" RELATED [ChemIDplus] synonym: "tetramethylene glycol" RELATED [ChemIDplus] xref: CAS:110-63-4 {source="ChemIDplus"} xref: CAS:110-63-4 {source="NIST Chemistry WebBook"} xref: DrugBank:DB01955 xref: PDBeChem:BU1 xref: PMID:11803699 {source="Europe PMC"} xref: PMID:15298490 {source="Europe PMC"} xref: PMID:16193534 {source="Europe PMC"} xref: PMID:17854202 {source="Europe PMC"} xref: PMID:18203723 {source="Europe PMC"} xref: PMID:19915428 {source="Europe PMC"} xref: PMID:20112336 {source="Europe PMC"} xref: PMID:21548140 {source="Europe PMC"} xref: PMID:21602812 {source="Europe PMC"} xref: Reaxys:1633445 {source="Reaxys"} xref: Wikipedia:1\,4-Butanediol is_a: BFO:0000004 ! independent continuant is_a: CHEBI:13643 ! glycol is_a: CHEBI:52684 ! butanediol relationship: has_role CHEBI:48356 ! protic solvent relationship: has_role CHEBI:50266 ! prodrug relationship: has_role CHEBI:50910 ! neurotoxin property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H10O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C4H10O2/c5-3-1-2-4-6/h5-6H,1-4H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "WERYXYBDKMZEQL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "90.12100" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "90.06808" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OCCCCO" xsd:string [Term] id: CHEBI:41609 name: carbonate namespace: chebi_ontology alt_id: CHEBI:29201 alt_id: CHEBI:41605 subset: 3_STAR synonym: "[CO3](2-)" RELATED [IUPAC] synonym: "carbonate" EXACT [IUPAC] synonym: "CARBONATE ION" RELATED [PDBeChem] synonym: "CO3(2-)" RELATED [ChEBI] synonym: "Karbonat" RELATED [ChEBI] synonym: "trioxidocarbonate(2-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3600898 {source="Beilstein"} xref: CAS:3812-32-6 {source="ChemIDplus"} xref: Gmelin:1559 {source="Gmelin"} xref: PDBeChem:CO3 is_a: CHEBI:35604 ! carbon oxoanion relationship: is_conjugate_base_of CHEBI:17544 ! hydrogencarbonate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.00890" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.98584" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([O-])=O" xsd:string [Term] id: CHEBI:42266 name: ethane namespace: chebi_ontology alt_id: CHEBI:23975 alt_id: CHEBI:42260 def: "An alkane comprising of two carbon atoms." [] subset: 3_STAR synonym: "Aethan" RELATED [ChEBI] synonym: "bimethyl" RELATED [NIST_Chemistry_WebBook] synonym: "C2H6" RELATED [ChEBI] synonym: "CH3-CH3" RELATED [IUPAC] synonym: "dimethyl" RELATED [NIST_Chemistry_WebBook] synonym: "Ethan" RELATED [ChEBI] synonym: "ETHANE" EXACT [PDBeChem] synonym: "ethane" EXACT IUPAC_NAME [IUPAC] synonym: "ethyl hydride" RELATED [NIST_Chemistry_WebBook] synonym: "methylmethane" RELATED [NIST_Chemistry_WebBook] synonym: "R-170" RELATED [ChEBI] xref: Beilstein:1730716 {source="Beilstein"} xref: CAS:74-84-0 {source="ChemIDplus"} xref: CAS:74-84-0 {source="NIST Chemistry WebBook"} xref: Gmelin:212 {source="Gmelin"} xref: PMID:12826252 {source="Europe PMC"} xref: PMID:14664856 {source="Europe PMC"} xref: PMID:16236899 {source="Europe PMC"} xref: Reaxys:1730716 {source="Reaxys"} xref: Wikipedia:Ethane is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:18310 ! alkane relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:78433 ! refrigerant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H6/c1-2/h1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OTMSDBZUPAUEDD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "30.06904" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "30.04695" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC" xsd:string [Term] id: CHEBI:42485 name: formyl group namespace: chebi_ontology alt_id: CHEBI:24089 alt_id: CHEBI:42480 subset: 3_STAR synonym: "-CH(O)" RELATED [IUPAC] synonym: "-CHO" RELATED [IUPAC] synonym: "aldehyde group" EXACT IUPAC_NAME [IUPAC] synonym: "carbaldehyde" EXACT IUPAC_NAME [IUPAC] synonym: "Fo" RELATED [CBN] synonym: "formyl" EXACT IUPAC_NAME [IUPAC] synonym: "FORMYL GROUP" EXACT [PDBeChem] synonym: "H-CO-" RELATED [IUPAC] synonym: "methanoyl" RELATED [IUPAC] xref: PDBeChem:FOR is_a: CHEBI:27207 ! univalent carboacyl group relationship: is_substituent_group_from CHEBI:30751 ! formic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "29.01804" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "29.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C(*)=O" xsd:string [Term] id: CHEBI:42820 name: guanidine namespace: chebi_ontology alt_id: CHEBI:24435 alt_id: CHEBI:42816 def: "An aminocarboxamidine, the parent compound of the guanidines." [] subset: 3_STAR synonym: "aminomethanamidine" RELATED [NIST_Chemistry_WebBook] synonym: "Gu" RELATED [ChEBI] synonym: "guanidin" RELATED [ChEBI] synonym: "GUANIDINE" EXACT [PDBeChem] synonym: "guanidine" EXACT IUPAC_NAME [IUPAC] synonym: "H2N-C(=NH)-NH2" RELATED [IUPAC] synonym: "iminourea" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:506044 {source="Beilstein"} xref: CAS:113-00-8 {source="ChemIDplus"} xref: CAS:113-00-8 {source="NIST Chemistry WebBook"} xref: Drug_Central:1344 {source="DrugCentral"} xref: DrugBank:DB00536 xref: Gmelin:100679 {source="Gmelin"} xref: PDBeChem:GAI xref: PMID:8070089 {source="Europe PMC"} xref: Reaxys:506044 {source="Reaxys"} xref: Wikipedia:Guanidine is_a: CHEBI:24436 ! guanidines is_a: CHEBI:35359 ! carboxamidine is_a: CHEBI:64708 ! one-carbon compound relationship: is_conjugate_base_of CHEBI:30087 ! guanidinium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH5N3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ZRALSGWEFCBTJO-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "59.07062" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.04835" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(N)=N" xsd:string [Term] id: CHEBI:43176 name: hydroxy group namespace: chebi_ontology alt_id: CHEBI:24706 alt_id: CHEBI:43171 subset: 3_STAR synonym: "-OH" RELATED [IUPAC] synonym: "hydroxy" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROXY GROUP" EXACT [PDBeChem] synonym: "hydroxy group" EXACT [UniProt] synonym: "hydroxyl" RELATED [ChEBI] synonym: "hydroxyl group" RELATED [ChEBI] xref: PDBeChem:OH is_a: CHEBI:33246 ! inorganic group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.00734" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*O[H]" xsd:string [Term] id: CHEBI:43254 name: (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:38337 ! pyrimidone relationship: is_tautomer_of CHEBI:17568 ! uracil [Term] id: CHEBI:43474 name: hydrogenphosphate namespace: chebi_ontology alt_id: CHEBI:29139 alt_id: CHEBI:43470 def: "A phosphate ion that is the conjugate base of dihydrogenphosphate." [] subset: 3_STAR synonym: "[P(OH)O3](2-)" RELATED [MolBase] synonym: "[PO3(OH)](2-)" RELATED [IUPAC] synonym: "HPO4(2-)" RELATED [IUPAC] synonym: "hydrogen phosphate" RELATED [ChEBI] synonym: "hydrogen(tetraoxidophosphate)(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogenphosphate" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROGENPHOSPHATE ION" RELATED [PDBeChem] synonym: "hydrogentetraoxophosphate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidotrioxidophosphate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "INORGANIC PHOSPHATE GROUP" RELATED [PDBeChem] synonym: "phosphate" RELATED [UniProt] xref: Gmelin:1998 {source="Gmelin"} xref: MolBase:1628 xref: PDBeChem:PI xref: PDBeChem:PO4 is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79388 ! divalent inorganic anion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: is_conjugate_acid_of CHEBI:18367 ! phosphate(3-) relationship: is_conjugate_base_of CHEBI:39745 ! dihydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "95.97930" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.96234" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OP([O-])([O-])=O" xsd:string [Term] id: CHEBI:45696 name: hydrogensulfate namespace: chebi_ontology alt_id: CHEBI:29199 alt_id: CHEBI:45693 subset: 3_STAR synonym: "[SO3(OH)](-)" RELATED [IUPAC] synonym: "HSO4(-)" RELATED [IUPAC] synonym: "HYDROGEN SULFATE" RELATED [PDBeChem] synonym: "hydrogen(tetraoxidosulfate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogensulfate" EXACT [IUPAC] synonym: "hydrogensulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidotrioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:2121 {source="Gmelin"} is_a: CHEBI:33482 ! sulfur oxoanion relationship: is_conjugate_acid_of CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:26836 ! sulfuric acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "97.07154" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS([O-])(=O)=O" xsd:string [Term] id: CHEBI:46629 name: oxo group namespace: chebi_ontology alt_id: CHEBI:29353 alt_id: CHEBI:44607 subset: 3_STAR synonym: "=O" RELATED [IUPAC] synonym: "oxo" EXACT IUPAC_NAME [IUPAC] synonym: "OXO GROUP" EXACT [PDBeChem] xref: PDBeChem:O is_a: CHEBI:33246 ! inorganic group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=*" xsd:string [Term] id: CHEBI:46787 name: solvent namespace: chebi_ontology def: "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." [] subset: 3_STAR synonym: "Loesungsmittel" RELATED [ChEBI] synonym: "solvant" RELATED [ChEBI] synonym: "solvents" RELATED [ChEBI] xref: Wikipedia:Solvent is_a: CHEBI:33232 ! application is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:46789 name: hydroxyether namespace: chebi_ontology def: "Any ether carrying a hydroxy group at unspecified position." [] subset: 3_STAR synonym: "hydroxyether" EXACT [ChEBI] is_a: CHEBI:25698 ! ether is_a: CHEBI:30879 ! alcohol [Term] id: CHEBI:46790 name: 2-methoxyethanol namespace: chebi_ontology alt_id: CHEBI:19677 alt_id: CHEBI:44217 def: "A hydroxyether that is ethanol substituted by a methoxy group at position 2." [] subset: 3_STAR synonym: "1-hydroxy-2-methoxyethane" RELATED [ChemIDplus] synonym: "2-hydroxyethyl methyl ether" RELATED [NIST_Chemistry_WebBook] synonym: "2-methoxy-1-ethanol" RELATED [ChemIDplus] synonym: "2-METHOXYETHANOL" EXACT [PDBeChem] synonym: "2-methoxyethanol" EXACT IUPAC_NAME [IUPAC] synonym: "3-oxa-1-butanol" RELATED [ChemIDplus] synonym: "beta-methoxyethanol" RELATED [NIST_Chemistry_WebBook] synonym: "HOCH2CH2OCH3" RELATED [NIST_Chemistry_WebBook] synonym: "Methyl cellosolve" RELATED [ChemIDplus] synonym: "methyl oxitol" RELATED [ChemIDplus] synonym: "monomethyl ethylene glycol ether" RELATED [ChemIDplus] xref: Beilstein:1731074 {source="ChemIDplus"} xref: CAS:109-86-4 {source="ChemIDplus"} xref: CAS:109-86-4 {source="NIST Chemistry WebBook"} xref: DrugBank:DB02806 xref: Gmelin:81877 {source="Gmelin"} xref: MetaCyc:2-METHOXYETHANOL xref: PDBeChem:MXE xref: PMID:11354470 {source="Europe PMC"} xref: PMID:24399739 {source="Europe PMC"} xref: PPDB:1639 xref: Reaxys:1731074 {source="Reaxys"} xref: Wikipedia:2-Methoxyethanol is_a: CHEBI:172390 ! glycol ether is_a: FBcv:0000570 ! 2-methoxyethanol equivalent_to: FBcv:0000570 ! 2-methoxyethanol relationship: has_role CHEBI:46787 ! solvent relationship: has_role CHEBI:48356 ! protic solvent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H8O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XNWFRZJHXBZDAG-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "76.09442" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "76.05243" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COCCO" xsd:string [Term] id: CHEBI:46883 name: carboxy group namespace: chebi_ontology alt_id: CHEBI:23025 alt_id: CHEBI:41420 subset: 3_STAR synonym: "-C(O)OH" RELATED [IUPAC] synonym: "-CO2H" RELATED [ChEBI] synonym: "-COOH" RELATED [IUPAC] synonym: "carboxy" EXACT IUPAC_NAME [IUPAC] synonym: "CARBOXY GROUP" EXACT [PDBeChem] synonym: "carboxyl group" RELATED [ChEBI] xref: PDBeChem:FMT is_a: CHEBI:33249 ! organyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01744" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(=O)O" xsd:string [Term] id: CHEBI:47017 name: tetrahydrofuranol namespace: chebi_ontology subset: 3_STAR synonym: "tetrahydrofuranols" RELATED [ChEBI] is_a: CHEBI:26912 ! oxolanes [Term] id: CHEBI:47018 name: monohydroxytetrahydrofuran namespace: chebi_ontology subset: 3_STAR synonym: "monohydroxytetrahydrofurans" RELATED [ChEBI] is_a: CHEBI:47017 ! tetrahydrofuranol [Term] id: CHEBI:47019 name: dihydroxytetrahydrofuran namespace: chebi_ontology subset: 3_STAR synonym: "dihydroxytetrahydrofurans" RELATED [ChEBI] is_a: CHEBI:47017 ! tetrahydrofuranol [Term] id: CHEBI:47857 name: ureas namespace: chebi_ontology alt_id: CHEBI:27220 alt_id: CHEBI:36947 subset: 3_STAR synonym: "urea derivatives" RELATED [ChEBI] is_a: CHEBI:33256 ! primary amide relationship: has_functional_parent CHEBI:16199 ! urea [Term] id: CHEBI:47868 name: photosensitizing agent namespace: chebi_ontology def: "A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells." [] subset: 3_STAR synonym: "photosensitising agent" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:47901 name: alkanesulfonic acid namespace: chebi_ontology alt_id: CHEBI:13809 alt_id: CHEBI:33553 def: "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group." [] subset: 3_STAR synonym: "alkanesulfonic acids" RELATED [ChEBI] synonym: "alkylsulfonic acids" RELATED [ChEBI] is_a: CHEBI:33551 ! organosulfonic acid relationship: has_part CHEBI:22323 ! alkyl group [Term] id: CHEBI:47916 name: flavonoid namespace: chebi_ontology alt_id: CHEBI:13638 alt_id: CHEBI:24044 alt_id: CHEBI:5077 def: "Any member of the 'superclass' flavonoids whose skeleton is based on 1-benzopyran with an aryl substituent at position 2. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds." [] subset: 3_STAR synonym: "2-aryl-1-benzopyran" RELATED [ChEBI] synonym: "2-aryl-1-benzopyrans" RELATED [ChEBI] synonym: "Flavonoid" EXACT [KEGG_COMPOUND] synonym: "flavonoids" RELATED [ChEBI] xref: KEGG:C01579 xref: Wikipedia:Flavonoid is_a: CHEBI:72544 ! flavonoids relationship: has_functional_parent CHEBI:26004 ! phenylpropanoid relationship: has_functional_parent CHEBI:38443 ! 1-benzopyran [Term] id: CHEBI:48024 name: 3'-hydroxyflavanones namespace: chebi_ontology def: "Any hydroxyflavanone with a hydroxy substituent at position 3' of the phenyl ring." [] subset: 3_STAR xref: MetaCyc:3-Hydroxy-Flavanones is_a: CHEBI:24697 ! hydroxyflavanone [Term] id: CHEBI:48154 name: sulfur oxide namespace: chebi_ontology subset: 3_STAR synonym: "oxides of sulfur" RELATED [ChEBI] synonym: "Schwefeloxide" RELATED [ChEBI] synonym: "sulfur oxides" RELATED [ChEBI] is_a: CHEBI:24836 ! inorganic oxide is_a: CHEBI:26835 ! sulfur molecular entity [Term] id: CHEBI:48219 name: disinfectant namespace: chebi_ontology def: "An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity." [] subset: 3_STAR synonym: "desinfectant" RELATED [ChEBI] synonym: "Desinfektionsmittel" RELATED [ChEBI] synonym: "disinfectants" RELATED [ChEBI] synonym: "disinfecting agent" RELATED [ChEBI] is_a: CHEBI:33281 ! antimicrobial agent [Term] id: CHEBI:48354 name: polar solvent namespace: chebi_ontology def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." [] subset: 3_STAR synonym: "polar solvent" EXACT IUPAC_NAME [IUPAC] synonym: "polar solvents" RELATED [ChEBI] is_a: CHEBI:46787 ! solvent [Term] id: CHEBI:48355 name: non-polar solvent namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:46787 ! solvent [Term] id: CHEBI:48356 name: protic solvent namespace: chebi_ontology def: "A polar solvent that is capable of acting as a hydron (proton) donor." [] subset: 3_STAR synonym: "protogenic solvent" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:39141 ! Bronsted acid is_a: CHEBI:48354 ! polar solvent [Term] id: CHEBI:48357 name: aprotic solvent namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:46787 ! solvent [Term] id: CHEBI:48358 name: polar aprotic solvent namespace: chebi_ontology def: "A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds." [] subset: 3_STAR synonym: "dipolar aprotic solvent" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:48354 ! polar solvent is_a: CHEBI:48357 ! aprotic solvent [Term] id: CHEBI:48376 name: carbamimidic acid namespace: chebi_ontology subset: 3_STAR synonym: "carbamimic acid" RELATED [ChemIDplus] synonym: "carbamimidic acid" EXACT IUPAC_NAME [IUPAC] synonym: "carbonamidimidic acid" RELATED [IUPAC] synonym: "H2N-C(=NH)-OH" RELATED [IUPAC] synonym: "H2N-C(OH)=NH" RELATED [IUPAC] synonym: "HO-C(=NH)-NH2" RELATED [IUPAC] synonym: "Isoharnstoff" RELATED [ChEBI] synonym: "isourea" RELATED [ChemIDplus] synonym: "pseudourea" RELATED [ChemIDplus] xref: Beilstein:773698 {source="Beilstein"} xref: CAS:4744-36-9 {source="ChemIDplus"} is_a: CHEBI:48379 ! isourea is_a: CHEBI:64708 ! one-carbon compound relationship: is_tautomer_of CHEBI:16199 ! urea property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH4N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "XSQUKJJJFZCRTK-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.05534" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.03236" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(O)=N" xsd:string [Term] id: CHEBI:48377 name: imidic acid namespace: chebi_ontology def: "Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH)." [] subset: 3_STAR synonym: "imidic acid" EXACT [ChEBI] synonym: "imidic acids" EXACT IUPAC_NAME [IUPAC] synonym: "imidic acids" RELATED [ChEBI] synonym: "imino acids" RELATED [IUPAC] is_a: CHEBI:33241 ! oxoacid derivative is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:48378 name: carboximidic acid namespace: chebi_ontology subset: 3_STAR synonym: "carboximidic acid" EXACT [ChEBI] synonym: "carboximidic acids" EXACT IUPAC_NAME [IUPAC] synonym: "carboximidic acids" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:48377 ! imidic acid [Term] id: CHEBI:48379 name: isourea namespace: chebi_ontology def: "A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives." [] subset: 3_STAR synonym: "isoureas" EXACT IUPAC_NAME [IUPAC] synonym: "isoureas" RELATED [ChEBI] is_a: CHEBI:48378 ! carboximidic acid [Term] id: CHEBI:48544 name: methanesulfonates namespace: chebi_ontology def: "Esters or salts of methanesulfonic acid." [] subset: 3_STAR is_a: CHEBI:33261 ! organosulfur compound relationship: has_functional_parent CHEBI:27376 ! methanesulfonic acid [Term] id: CHEBI:48578 name: radical scavenger namespace: chebi_ontology def: "A role played by a substance that can react readily with, and thereby eliminate, radicals." [] subset: 3_STAR synonym: "free radical scavengers" RELATED [ChEBI] synonym: "free-radical scavenger" RELATED [ChEBI] is_a: CHEBI:22586 ! antioxidant [Term] id: CHEBI:48706 name: antagonist namespace: chebi_ontology def: "Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances." [] subset: 3_STAR synonym: "antagonist" EXACT IUPAC_NAME [IUPAC] synonym: "antagonista" RELATED [ChEBI] synonym: "antagoniste" RELATED [ChEBI] synonym: "antagonists" RELATED [ChEBI] is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:48854 name: sulfurous acid namespace: chebi_ontology alt_id: CHEBI:26837 alt_id: CHEBI:9344 subset: 3_STAR synonym: "[SO(OH)2]" RELATED [IUPAC] synonym: "acide sulfureux" RELATED [ChEBI] synonym: "acido sulfuroso" RELATED [ChEBI] synonym: "dihydrogen trioxosulfate" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidooxidosulfur" EXACT IUPAC_NAME [IUPAC] synonym: "H2SO3" RELATED [IUPAC] synonym: "S(O)(OH)2" RELATED [IUPAC] synonym: "schweflige Saeure" RELATED [ChemIDplus] synonym: "Sulfite" RELATED [KEGG_COMPOUND] synonym: "Sulfurous acid" EXACT [KEGG_COMPOUND] synonym: "sulfurous acid" EXACT IUPAC_NAME [IUPAC] synonym: "sulphurous acid" RELATED [ChemIDplus] synonym: "trioxosulfuric acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:7782-99-2 {source="ChemIDplus"} xref: Gmelin:1458 {source="Gmelin"} xref: KEGG:C00094 xref: KNApSAcK:C00019662 xref: PDBeChem:SO3 xref: UM-BBD_compID:c0348 {source="UM-BBD"} is_a: CHEBI:33402 ! sulfur oxoacid relationship: is_conjugate_acid_of CHEBI:17137 ! hydrogensulfite relationship: is_tautomer_of CHEBI:29214 ! sulfonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "82.08008" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "81.97247" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OS(O)=O" xsd:string [Term] id: CHEBI:48857 name: sulfite salt namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:24839 ! inorganic salt is_a: CHEBI:26823 ! sulfites [Term] id: CHEBI:48873 name: cholinergic antagonist namespace: chebi_ontology def: "Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists." [] subset: 3_STAR synonym: "acetylcholine antagonists" RELATED [ChEBI] synonym: "acetylcholine receptor antagonist" RELATED [IUPHAR] synonym: "agent anticholinergique" RELATED [ChEBI] synonym: "agente anticolinergico" RELATED [ChEBI] synonym: "agentes anticolinergicos" RELATED [ChEBI] synonym: "anticholinergic agents" RELATED [ChEBI] synonym: "anticholinergics" RELATED [ChEBI] synonym: "Anticholinergika" RELATED [ChEBI] synonym: "Anticholinergikum" RELATED [ChEBI] synonym: "anticholinergiques" RELATED [ChEBI] synonym: "anticolinergicos" RELATED [ChEBI] synonym: "cholinergic-blocking agents" RELATED [ChEBI] is_a: CHEBI:38323 ! cholinergic drug [Term] id: CHEBI:48927 name: N-acyl-L-alpha-amino acid namespace: chebi_ontology alt_id: CHEBI:13240 alt_id: CHEBI:7232 def: "Any L-alpha-amino acid carrying an N-acyl substituent." [] subset: 3_STAR synonym: "N-Acyl-L-amino acid" RELATED [KEGG_COMPOUND] xref: KEGG:C02850 is_a: CHEBI:21644 ! N-acyl-L-amino acid relationship: has_functional_parent CHEBI:15705 ! L-alpha-amino acid relationship: is_conjugate_acid_of CHEBI:59874 ! N-acyl-L-alpha-amino acid anion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H3NO3R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "101.061" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "101.01129" xsd:string [Term] id: CHEBI:49637 name: hydrogen atom namespace: chebi_ontology alt_id: CHEBI:24634 alt_id: CHEBI:49636 subset: 3_STAR synonym: "1H" RELATED [IUPAC] synonym: "H" RELATED [IUPAC] synonym: "hidrogeno" RELATED [ChEBI] synonym: "hydrogen" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen" RELATED [ChEBI] synonym: "hydrogene" RELATED [ChEBI] synonym: "Wasserstoff" RELATED [ChEBI] xref: WebElements:H is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33559 ! s-block element atom is_a: FBcv:0000553 ! inorganic compound relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1.00794" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.00783" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]" xsd:string [Term] id: CHEBI:50047 name: organic amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." [] subset: 3_STAR synonym: "organic amino compounds" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35352 ! organonitrogen compound relationship: has_parent_hydride CHEBI:16134 ! ammonia relationship: has_role CHEBI:39142 ! Bronsted base [Term] id: CHEBI:50102 name: N-methyl-N-nitrosourea namespace: chebi_ontology alt_id: CHEBI:25565 alt_id: CHEBI:34843 alt_id: CHEBI:50101 def: "A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups." [] subset: 3_STAR synonym: "1-(aminocarbonyl)-1-methyl-2-oxohydrazine" RELATED [NIST_Chemistry_WebBook] synonym: "1-methyl-1-nitrosourea" EXACT IUPAC_NAME [IUPAC] synonym: "1-nitroso-1-methylurea" RELATED [ChemIDplus] synonym: "Methylnitrosoharnstoff" RELATED [ChEBI] synonym: "Methylnitrosourea" RELATED [KEGG_COMPOUND] synonym: "methylnitrosouree" RELATED [ChemIDplus] synonym: "MNU" RELATED [ChemIDplus] synonym: "N-methyl-N-nitrosocarbamide" RELATED [ChemIDplus] synonym: "N-Methyl-N-nitrosoharnstoff" RELATED [ChEBI] synonym: "N-Methyl-N-nitrosourea" EXACT [KEGG_COMPOUND] synonym: "N-methyl-N-nitrosouree" RELATED [ChEBI] synonym: "N-nitroso-N-methylcarbamide" RELATED [NIST_Chemistry_WebBook] synonym: "N-Nitroso-N-methylharnstoff" RELATED [ChEBI] synonym: "N-nitroso-N-methylurea" RELATED [ChemIDplus] synonym: "N-nitroso-N-methyluree" RELATED [ChEBI] synonym: "N-nitrosomethylurea" RELATED [NIST_Chemistry_WebBook] synonym: "nitrosomethylurea" RELATED [NIST_Chemistry_WebBook] synonym: "NMH" RELATED [ChemIDplus] synonym: "NMU" RELATED [ChemIDplus] xref: Beilstein:1756040 {source="Beilstein"} xref: CAS:684-93-5 {source="KEGG COMPOUND"} xref: CAS:684-93-5 {source="NIST Chemistry WebBook"} xref: CAS:684-93-5 {source="ChemIDplus"} xref: KEGG:C14595 xref: PMID:11479921 {source="Europe PMC"} xref: PMID:12767522 {source="Europe PMC"} xref: PMID:15990165 {source="Europe PMC"} xref: PMID:19181008 {source="Europe PMC"} xref: PMID:24441676 {source="Europe PMC"} xref: PMID:6243984 {source="Europe PMC"} xref: PMID:8098217 {source="Europe PMC"} xref: PMID:8603364 {source="Europe PMC"} xref: Wikipedia:N-Methyl-N-nitrosourea is_a: CHEBI:76551 ! N-nitrosoureas is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000592 ! nitrosomethyl urea equivalent_to: FBcv:0000592 ! nitrosomethyl urea relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:50903 ! carcinogenic agent relationship: has_role CHEBI:50905 ! teratogenic agent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H5N3O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5N3O2/c1-5(4-7)2(3)6/h1H3,(H2,3,6)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "ZRKWMRDKSOPRRS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "103.08012" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "103.03818" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CN(N=O)C(N)=O" xsd:string [Term] id: CHEBI:50218 name: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor namespace: chebi_ontology alt_id: CHEBI:76774 def: "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*)." [] subset: 3_STAR synonym: "EC 3.1.4.* (phosphoric diester hydrolase) inhibitors" RELATED [ChEBI] synonym: "phosphodiesterase inhibitor" RELATED [ChEBI] synonym: "phosphodiesterase inhibitors" RELATED [ChEBI] synonym: "phosphoric diester hydrolase (EC 3.1.4.*) inhibitor" RELATED [ChEBI] synonym: "phosphoric diester hydrolase (EC 3.1.4.*) inhibitors" RELATED [ChEBI] synonym: "phosphoric diester hydrolase inhibitor" RELATED [ChEBI] synonym: "phosphoric diester hydrolase inhibitors" RELATED [ChEBI] is_a: CHEBI:76760 ! EC 3.1.* (ester hydrolase) inhibitor [Term] id: CHEBI:50247 name: antidote namespace: chebi_ontology def: "Any protective agent counteracting or neutralizing the action of poisons." [] subset: 3_STAR synonym: "antidotes" RELATED [ChEBI] is_a: CHEBI:50267 ! protective agent [Term] id: CHEBI:50266 name: prodrug namespace: chebi_ontology def: "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug." [] subset: 3_STAR synonym: "Prodrugs" RELATED [ChEBI] xref: PMID:23993918 {source="Europe PMC"} xref: PMID:23998799 {source="Europe PMC"} xref: PMID:24329110 {source="Europe PMC"} xref: PMID:24628402 {source="Europe PMC"} xref: PMID:24709544 {source="Europe PMC"} xref: PMID:25144792 {source="Europe PMC"} xref: PMID:25157234 {source="Europe PMC"} xref: PMID:25269430 {source="Europe PMC"} xref: PMID:25391982 {source="Europe PMC"} xref: PMID:25591121 {source="Europe PMC"} xref: PMID:25620096 {source="Europe PMC"} xref: PMID:25795057 {source="Europe PMC"} xref: PMID:26028253 {source="Europe PMC"} xref: PMID:26184144 {source="Europe PMC"} xref: PMID:28070577 {source="Europe PMC"} xref: PMID:28215138 {source="Europe PMC"} xref: PMID:28219047 {source="Europe PMC"} xref: PMID:28259775 {source="Europe PMC"} xref: PMID:28319647 {source="Europe PMC"} xref: PMID:28329729 {source="Europe PMC"} xref: PMID:28334528 {source="Europe PMC"} xref: Wikipedia:Prodrug is_a: CHEBI:136859 ! pro-agent is_a: CHEBI:23888 ! drug [Term] id: CHEBI:50267 name: protective agent namespace: chebi_ontology def: "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." [] subset: 3_STAR synonym: "chemoprotectant" RELATED [ChEBI] synonym: "chemoprotectants" RELATED [ChEBI] synonym: "chemoprotective agent" RELATED [ChEBI] synonym: "chemoprotective agents" RELATED [ChEBI] synonym: "protective agents" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:50276 name: EC 5.99.1.2 (DNA topoisomerase) inhibitor namespace: chebi_ontology def: "A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA." [] subset: 3_STAR synonym: "DNA topoisomerase inhibitor" RELATED [ChEBI] synonym: "DNA topoisomerase inhibitors" RELATED [ChEBI] synonym: "EC 5.99.1.2 (DNA topoisomerase) inhibitors" RELATED [ChEBI] synonym: "EC 5.99.1.2 (topoisomerase I) inhibitor" RELATED [ChEBI] synonym: "EC 5.99.1.2 (topoisomerase I) inhibitors" RELATED [ChEBI] synonym: "EC 5.99.1.2 inhibitor" RELATED [ChEBI] synonym: "EC 5.99.1.2 inhibitors" RELATED [ChEBI] synonym: "topoisomerase I (EC 5.99.1.2) inhibitor" RELATED [ChEBI] synonym: "topoisomerase I (EC 5.99.1.2) inhibitors" RELATED [ChEBI] synonym: "topoisomerase I inhibitor" RELATED [ChEBI] synonym: "topoisomerase I inhibitors" RELATED [ChEBI] synonym: "type I DNA topoisomerase inhibitor" RELATED [ChEBI] synonym: "type I DNA topoisomerase inhibitors" RELATED [ChEBI] is_a: CHEBI:70727 ! topoisomerase inhibitor [Term] id: CHEBI:50297 name: canonical nucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical nucleotide residues" RELATED [ChEBI] is_a: CHEBI:50319 ! nucleotide residue [Term] id: CHEBI:50298 name: canonical deoxyribonucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical deoxyribonucleotide residues" RELATED [ChEBI] is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50312 name: onium compound namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:50313 name: onium cation namespace: chebi_ontology def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." [] subset: 3_STAR synonym: "onium cations" EXACT IUPAC_NAME [IUPAC] synonym: "onium cations" RELATED [ChEBI] synonym: "onium ion" RELATED [ChEBI] synonym: "onium ions" RELATED [ChEBI] is_a: CHEBI:50312 ! onium compound [Term] id: CHEBI:50314 name: fluoronium namespace: chebi_ontology subset: 3_STAR synonym: "[FH2](+)" RELATED [ChEBI] synonym: "fluoranium" EXACT IUPAC_NAME [IUPAC] synonym: "fluoronium" EXACT IUPAC_NAME [IUPAC] synonym: "H2F(+)" RELATED [IUPAC] is_a: CHEBI:50313 ! onium cation relationship: is_conjugate_acid_of CHEBI:29228 ! hydrogen fluoride property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "FH2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/FH2/h1H2/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YNESUKSMQODWNS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "21.01428" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "21.01350" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][F+][H]" xsd:string [Term] id: CHEBI:50315 name: chloronium namespace: chebi_ontology subset: 3_STAR synonym: "[ClH2](+)" RELATED [IUPAC] synonym: "chloranium" EXACT IUPAC_NAME [IUPAC] synonym: "chloronium" EXACT IUPAC_NAME [IUPAC] synonym: "H2Cl(+)" RELATED [IUPAC] xref: Gmelin:331 {source="Gmelin"} is_a: CHEBI:50313 ! onium cation relationship: is_conjugate_acid_of CHEBI:17883 ! hydrogen chloride property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "ClH2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/ClH2/h1H2/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IGJWHVUMEJASKV-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "37.46858" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "36.98395" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][Cl+][H]" xsd:string [Term] id: CHEBI:50319 name: nucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "nucleotide residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50320 name: nucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "nucleoside residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50325 name: proteinogenic amino-acid side-chain group namespace: chebi_ontology def: "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." [] subset: 3_STAR synonym: "canonical amino-acid side-chain" RELATED [ChEBI] synonym: "canonical amino-acid side-chains" RELATED [ChEBI] synonym: "proteinogenic amino-acid side-chain" RELATED [ChEBI] synonym: "proteinogenic amino-acid side-chain groups" RELATED [ChEBI] synonym: "proteinogenic amino-acid side-chains" RELATED [ChEBI] is_a: CHEBI:33249 ! organyl group [Term] id: CHEBI:50326 name: sulfanylmethyl group namespace: chebi_ontology subset: 3_STAR synonym: "-CH2-SH" RELATED [IUPAC] synonym: "cysteine side-chain" RELATED [ChEBI] synonym: "HS-CH2-" RELATED [IUPAC] synonym: "sulfanylmethyl" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "47.10052" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "46.99555" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "SC*" xsd:string [Term] id: CHEBI:50329 name: 2-carboxyethyl group namespace: chebi_ontology subset: 3_STAR synonym: "2-carboxyethyl" EXACT IUPAC_NAME [IUPAC] synonym: "glutamic acid side-chain" RELATED [ChEBI] is_a: CHEBI:50325 ! proteinogenic amino-acid side-chain group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H5O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "73.07060" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "73.02895" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(CC(=O)O)*" xsd:string [Term] id: CHEBI:50683 name: EC 1.5.1.3 (dihydrofolate reductase) inhibitor namespace: chebi_ontology def: "An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3)." [] subset: 3_STAR synonym: "7,8-dihydrofolate reductase inhibitor" RELATED [ChEBI] synonym: "7,8-dihydrofolate reductase inhibitors" RELATED [ChEBI] synonym: "DHFR inhibitor" RELATED [ChEBI] synonym: "DHFR inhibitors" RELATED [ChEBI] synonym: "dihydrofolate reductase (EC 1.5.1.3) inhibitor" RELATED [ChEBI] synonym: "dihydrofolate reductase (EC 1.5.1.3) inhibitors" RELATED [ChEBI] synonym: "dihydrofolate reductase inhibitor" RELATED [ChEBI] synonym: "dihydrofolate reductase inhibitors" RELATED [ChEBI] synonym: "dihydrofolic acid reductase inhibitor" RELATED [ChEBI] synonym: "dihydrofolic acid reductase inhibitors" RELATED [ChEBI] synonym: "dihydrofolic reductase inhibitor" RELATED [ChEBI] synonym: "dihydrofolic reductase inhibitors" RELATED [ChEBI] synonym: "EC 1.5.1.3 (dihydrofolate reductase) inhibitors" RELATED [ChEBI] synonym: "EC 1.5.1.3 inhibitor" RELATED [ChEBI] synonym: "EC 1.5.1.3 inhibitors" RELATED [ChEBI] synonym: "folic acid reductase inhibitor" RELATED [ChEBI] synonym: "folic acid reductase inhibitors" RELATED [ChEBI] synonym: "folic reductase inhibitor" RELATED [ChEBI] synonym: "folic reductase inhibitors" RELATED [ChEBI] synonym: "NADPH-dihydrofolate reductase inhibitor" RELATED [ChEBI] synonym: "NADPH-dihydrofolate reductase inhibitors" RELATED [ChEBI] synonym: "tetrahydrofolate dehydrogenase inhibitor" RELATED [ChEBI] synonym: "tetrahydrofolate dehydrogenase inhibitors" RELATED [ChEBI] xref: Wikipedia:Dihydrofolate_reductase_inhibitor is_a: CHEBI:73913 ! antifolate is_a: CHEBI:76863 ! EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor [Term] id: CHEBI:50684 name: cross-linking reagent namespace: chebi_ontology def: "A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified." [] subset: 3_STAR synonym: "cross-linking reagents" RELATED [ChEBI] is_a: CHEBI:33893 ! reagent [Term] id: CHEBI:50699 name: oligosaccharide namespace: chebi_ontology alt_id: CHEBI:25679 alt_id: CHEBI:35319 alt_id: CHEBI:7758 def: "A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues." [] subset: 3_STAR synonym: "O-glycosylglycoside" RELATED [ChEBI] synonym: "O-glycosylglycosides" RELATED [ChEBI] synonym: "oligosacarido" RELATED [ChEBI] synonym: "oligosacaridos" RELATED [IUPAC] synonym: "Oligosaccharide" EXACT [KEGG_COMPOUND] synonym: "oligosaccharides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00930 is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:167559 ! glycan [Term] id: CHEBI:50733 name: nutraceutical namespace: chebi_ontology def: "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." [] subset: 3_STAR synonym: "Dietary Supplement" RELATED [ChEBI] synonym: "Food Supplementation" RELATED [ChEBI] synonym: "Nutritional supplement" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:50750 name: EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor namespace: chebi_ontology alt_id: CHEBI:132229 alt_id: CHEBI:50234 def: "A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands." [] subset: 3_STAR synonym: "DNA gyrase inhibitor" RELATED [ChEBI] synonym: "DNA gyrase inhibitors" RELATED [ChEBI] synonym: "DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor" RELATED [ChEBI] synonym: "DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors" RELATED [ChEBI] synonym: "DNA topoisomerase (ATP-hydrolysing) inhibitor" RELATED [ChEBI] synonym: "DNA topoisomerase (ATP-hydrolysing) inhibitors" RELATED [ChEBI] synonym: "DNA topoisomerase II inhibitor" RELATED [ChEBI] synonym: "DNA topoisomerase II inhibitors" RELATED [ChEBI] synonym: "EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor" RELATED [ChEBI] synonym: "EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors" RELATED [ChEBI] synonym: "EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors" RELATED [ChEBI] synonym: "EC 5.99.1.3 inhibitor" RELATED [ChEBI] synonym: "EC 5.99.1.3 inhibitors" RELATED [ChEBI] synonym: "inhibitor of type II topoisomerase" RELATED [ChEBI] synonym: "inhibitors of type II topoisomerase" RELATED [ChEBI] synonym: "topoisomerase II inhibitor" RELATED [ChEBI] synonym: "topoisomerase II inhibitors" RELATED [ChEBI] synonym: "topoisomerase-II inhibitor" RELATED [ChEBI] synonym: "topoisomerase-II inhibitors" RELATED [ChEBI] synonym: "type II DNA topoisomerase inhibitor" RELATED [ChEBI] synonym: "type II DNA topoisomerase inhibitors" RELATED [ChEBI] is_a: CHEBI:70727 ! topoisomerase inhibitor [Term] id: CHEBI:50846 name: immunomodulator namespace: chebi_ontology def: "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." [] subset: 3_STAR synonym: "Biomodulator" RELATED [ChEBI] synonym: "Immune factor" RELATED [ChEBI] synonym: "Immunologic factor" RELATED [ChEBI] synonym: "Immunological factor" RELATED [ChEBI] synonym: "immunomodulators" RELATED [ChEBI] xref: Wikipedia:Immunotherapy is_a: CHEBI:23888 ! drug is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:50860 name: organic molecular entity namespace: chebi_ontology alt_id: CHEBI:25700 alt_id: CHEBI:33244 def: "Any molecular entity that contains carbon." [] subset: 3_STAR synonym: "organic compounds" RELATED [ChEBI] synonym: "organic entity" RELATED [ChEBI] synonym: "organic molecular entities" RELATED [ChEBI] is_a: CHEBI:33582 ! carbon group molecular entity relationship: has_part CHEBI:27594 ! carbon atom [Term] id: CHEBI:50893 name: azaarene namespace: chebi_ontology subset: 3_STAR synonym: "azaarenes" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:50902 name: genotoxin namespace: chebi_ontology def: "A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells." [] subset: 3_STAR synonym: "genotoxic agent" RELATED [ChEBI] synonym: "genotoxic agents" RELATED [ChEBI] synonym: "genotoxins" RELATED [ChEBI] xref: Wikipedia:Genotoxicity is_a: CHEBI:52209 ! aetiopathogenetic role [Term] id: CHEBI:50903 name: carcinogenic agent namespace: chebi_ontology def: "A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities." [] subset: 3_STAR synonym: "agente carcinogeno" RELATED [ChEBI] synonym: "cancerigene" RELATED [ChEBI] synonym: "cancerogene" RELATED [ChEBI] synonym: "carcinogen" RELATED [ChEBI] synonym: "carcinogene" RELATED [ChEBI] synonym: "carcinogenic agents" RELATED [ChEBI] synonym: "carcinogeno" RELATED [ChEBI] synonym: "carcinogens" RELATED [ChEBI] is_a: CHEBI:52209 ! aetiopathogenetic role [Term] id: CHEBI:50904 name: allergen namespace: chebi_ontology def: "A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy." [] subset: 3_STAR synonym: "alergeno" RELATED [ChEBI] synonym: "allergene" RELATED [ChEBI] synonym: "allergenic agent" RELATED [ChEBI] xref: Wikipedia:Allergen is_a: CHEBI:52209 ! aetiopathogenetic role [Term] id: CHEBI:50905 name: teratogenic agent namespace: chebi_ontology def: "A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect." [] subset: 3_STAR synonym: "agent teratogene" RELATED [ChEBI] synonym: "teratogen" RELATED [ChEBI] synonym: "teratogeno" RELATED [ChEBI] is_a: CHEBI:52209 ! aetiopathogenetic role [Term] id: CHEBI:50906 name: role namespace: chebi_ontology def: "A role is particular behaviour which a material entity may exhibit." [] subset: 3_STAR [Term] id: CHEBI:50908 name: hepatotoxic agent namespace: chebi_ontology def: "A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals." [] subset: 3_STAR synonym: "agente hepatotoxico" RELATED [ChEBI] synonym: "hepatotoxic agents" RELATED [ChEBI] synonym: "hepatotoxicant" RELATED [ChEBI] synonym: "hepatotoxicants" RELATED [ChEBI] synonym: "hepatotoxin" RELATED [ChEBI] synonym: "hepatotoxins" RELATED [ChEBI] synonym: "hepatoxic agent" RELATED [ChEBI] synonym: "hepatoxicant" RELATED [ChEBI] is_a: CHEBI:52209 ! aetiopathogenetic role [Term] id: CHEBI:50910 name: neurotoxin namespace: chebi_ontology alt_id: CHEBI:50911 def: "A poison that interferes with the functions of the nervous system." [] subset: 3_STAR synonym: "agente neurotoxico" RELATED [ChEBI] synonym: "nerve poison" RELATED [ChEBI] synonym: "nerve poisons" RELATED [ChEBI] synonym: "neurotoxic agent" RELATED [ChEBI] synonym: "neurotoxic agents" RELATED [ChEBI] synonym: "neurotoxicant" RELATED [ChEBI] synonym: "neurotoxins" RELATED [ChEBI] xref: Wikipedia:Neurotoxin is_a: CHEBI:52209 ! aetiopathogenetic role is_a: CHEBI:64909 ! poison [Term] id: CHEBI:50925 name: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor namespace: chebi_ontology alt_id: CHEBI:75764 def: "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine." [] subset: 3_STAR synonym: "A-kinase inhibitor" RELATED [ChEBI] synonym: "A-kinase inhibitors" RELATED [ChEBI] synonym: "AP50 kinase inhibitor" RELATED [ChEBI] synonym: "AP50 kinase inhibitors" RELATED [ChEBI] synonym: "ATP-protein transphosphorylase inhibitor" RELATED [ChEBI] synonym: "ATP-protein transphosphorylase inhibitors" RELATED [ChEBI] synonym: "ATP:protein phosphotransferase (non-specific) inhibitor" RELATED [ChEBI] synonym: "ATP:protein phosphotransferase (non-specific) inhibitors" RELATED [ChEBI] synonym: "betaIIPKC inhibitor" RELATED [ChEBI] synonym: "betaIIPKC inhibitors" RELATED [ChEBI] synonym: "BR serine/threonine-protein kinase 2 inhibitor" RELATED [ChEBI] synonym: "BR serine/threonine-protein kinase 2 inhibitors" RELATED [ChEBI] synonym: "calcium-dependent protein kinase C inhibitor" RELATED [ChEBI] synonym: "calcium-dependent protein kinase C inhibitors" RELATED [ChEBI] synonym: "calcium/phospholipid-dependent protein kinase inhibitor" RELATED [ChEBI] synonym: "calcium/phospholipid-dependent protein kinase inhibitors" RELATED [ChEBI] synonym: "cAMP-dependent protein kinase A inhibitor" RELATED [ChEBI] synonym: "cAMP-dependent protein kinase A inhibitors" RELATED [ChEBI] synonym: "cAMP-dependent protein kinase inhibitor" RELATED [ChEBI] synonym: "cAMP-dependent protein kinase inhibitors" RELATED [ChEBI] synonym: "casein kinase (phosphorylating) inhibitor" RELATED [ChEBI] synonym: "casein kinase (phosphorylating) inhibitors" RELATED [ChEBI] synonym: "casein kinase 2 inhibitor" RELATED [ChEBI] synonym: "casein kinase 2 inhibitors" RELATED [ChEBI] synonym: "casein kinase I inhibitor" RELATED [ChEBI] synonym: "casein kinase I inhibitors" RELATED [ChEBI] synonym: "casein kinase II inhibitor" RELATED [ChEBI] synonym: "casein kinase II inhibitors" RELATED [ChEBI] synonym: "casein kinase inhibitor" RELATED [ChEBI] synonym: "casein kinase inhibitors" RELATED [ChEBI] synonym: "cGMP-dependent protein kinase inhibitor" RELATED [ChEBI] synonym: "cGMP-dependent protein kinase inhibitors" RELATED [ChEBI] synonym: "CK-2 inhibitor" RELATED [ChEBI] synonym: "CK-2 inhibitors" RELATED [ChEBI] synonym: "CKI inhibitor" RELATED [ChEBI] synonym: "CKI inhibitors" RELATED [ChEBI] synonym: "CKII inhibitor" RELATED [ChEBI] synonym: "CKII inhibitors" RELATED [ChEBI] synonym: "cyclic AMP-dependent protein kinase A inhibitor" RELATED [ChEBI] synonym: "cyclic AMP-dependent protein kinase A inhibitors" RELATED [ChEBI] synonym: "cyclic AMP-dependent protein kinase inhibitor" RELATED [ChEBI] synonym: "cyclic AMP-dependent protein kinase inhibitors" RELATED [ChEBI] synonym: "cyclic monophosphate-dependent protein kinase inhibitor" RELATED [ChEBI] synonym: "cyclic monophosphate-dependent protein kinase inhibitors" RELATED [ChEBI] synonym: "cyclic nucleotide-dependent protein kinase inhibitor" RELATED [ChEBI] synonym: "cyclic nucleotide-dependent protein kinase inhibitors" RELATED [ChEBI] synonym: "cyclin-dependent kinase inhibitor" RELATED [ChEBI] synonym: "cyclin-dependent kinase inhibitors" RELATED [ChEBI] synonym: "dsk1 inhibitor" RELATED [ChEBI] synonym: "dsk1 inhibitors" RELATED [ChEBI] synonym: "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors" RELATED [ChEBI] synonym: "EC 2.7.11.1 inhibitor" RELATED [ChEBI] synonym: "EC 2.7.11.1 inhibitors" RELATED [ChEBI] synonym: "epsilon PKC inhibitor" RELATED [ChEBI] synonym: "epsilon PKC inhibitors" RELATED [ChEBI] synonym: "glycogen synthase a kinase inhibitor" RELATED [ChEBI] synonym: "glycogen synthase a kinase inhibitors" RELATED [ChEBI] synonym: "glycogen synthase kinase inhibitor" RELATED [ChEBI] synonym: "glycogen synthase kinase inhibitors" RELATED [ChEBI] synonym: "HIPK2 inhibitor" RELATED [ChEBI] synonym: "HIPK2 inhibitors" RELATED [ChEBI] synonym: "Hpr kinase inhibitor" RELATED [ChEBI] synonym: "Hpr kinase inhibitors" RELATED [ChEBI] synonym: "hydroxyalkyl-protein kinase inhibitor" RELATED [ChEBI] synonym: "hydroxyalkyl-protein kinase inhibitors" RELATED [ChEBI] synonym: "M phase-specific cdc2 kinase inhibitor" RELATED [ChEBI] synonym: "M phase-specific cdc2 kinase inhibitors" RELATED [ChEBI] synonym: "mitogen-activated S6 kinase inhibitor" RELATED [ChEBI] synonym: "mitogen-activated S6 kinase inhibitors" RELATED [ChEBI] synonym: "MKNK2 inhibitor" RELATED [ChEBI] synonym: "MKNK2 inhibitors" RELATED [ChEBI] synonym: "non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor" RELATED [ChEBI] synonym: "non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors" RELATED [ChEBI] synonym: "non-specific serine/threonine protein kinase inhibitor" RELATED [ChEBI] synonym: "non-specific serine/threonine protein kinase inhibitors" RELATED [ChEBI] synonym: "p21 activated kinase-1 inhibitor" RELATED [ChEBI] synonym: "p21 activated kinase-1 inhibitors" RELATED [ChEBI] synonym: "p82 kinase inhibitor" RELATED [ChEBI] synonym: "p82 kinase inhibitors" RELATED [ChEBI] synonym: "PAK-1 inhibitor" RELATED [ChEBI] synonym: "PAK-1 inhibitors" RELATED [ChEBI] synonym: "PAK1 inhibitor" RELATED [ChEBI] synonym: "PAK1 inhibitors" RELATED [ChEBI] synonym: "phosphorylase b kinase kinase inhibitor" RELATED [ChEBI] synonym: "phosphorylase b kinase kinase inhibitors" RELATED [ChEBI] synonym: "PKA inhibitor" RELATED [ChEBI] synonym: "PKA inhibitors" RELATED [ChEBI] synonym: "protein glutamyl kinase inhibitor" RELATED [ChEBI] synonym: "protein glutamyl kinase inhibitors" RELATED [ChEBI] synonym: "protein kinase (phosphorylating) inhibitor" RELATED [ChEBI] synonym: "protein kinase (phosphorylating) inhibitors" RELATED [ChEBI] synonym: "protein kinase A inhibitor" RELATED [ChEBI] synonym: "protein kinase A inhibitors" RELATED [ChEBI] synonym: "protein kinase CK2 inhibitor" RELATED [ChEBI] synonym: "protein kinase CK2 inhibitors" RELATED [ChEBI] synonym: "protein kinase p58 inhibitor" RELATED [ChEBI] synonym: "protein kinase p58 inhibitors" RELATED [ChEBI] synonym: "protein phosphokinase inhibitor" RELATED [ChEBI] synonym: "protein phosphokinase inhibitors" RELATED [ChEBI] synonym: "protein serine kinase inhibitor" RELATED [ChEBI] synonym: "protein serine kinase inhibitors" RELATED [ChEBI] synonym: "protein serine-threonine kinase inhibitor" RELATED [ChEBI] synonym: "protein serine-threonine kinase inhibitors" RELATED [ChEBI] synonym: "protein-aspartyl kinase inhibitor" RELATED [ChEBI] synonym: "protein-aspartyl kinase inhibitors" RELATED [ChEBI] synonym: "protein-cysteine kinase inhibitor" RELATED [ChEBI] synonym: "protein-cysteine kinase inhibitors" RELATED [ChEBI] synonym: "protein-serine kinase inhibitor" RELATED [ChEBI] synonym: "protein-serine kinase inhibitors" RELATED [ChEBI] synonym: "protein-serine/threonine kinase inhibitors" RELATED [ChEBI] synonym: "Prp4 protein kinase inhibitor" RELATED [ChEBI] synonym: "Prp4 protein kinase inhibitors" RELATED [ChEBI] synonym: "Raf kinase inhibitor" RELATED [ChEBI] synonym: "Raf kinase inhibitors" RELATED [ChEBI] synonym: "Raf-1 inhibitor" RELATED [ChEBI] synonym: "Raf-1 inhibitors" RELATED [ChEBI] synonym: "ribosomal protein S6 kinase II inhibitor" RELATED [ChEBI] synonym: "ribosomal protein S6 kinase II inhibitors" RELATED [ChEBI] synonym: "ribosomal S6 protein kinase inhibitor" RELATED [ChEBI] synonym: "ribosomal S6 protein kinase inhibitors" RELATED [ChEBI] synonym: "serine kinase inhibitor" RELATED [ChEBI] synonym: "serine kinase inhibitors" RELATED [ChEBI] synonym: "serine protein kinase inhibitor" RELATED [ChEBI] synonym: "serine protein kinase inhibitors" RELATED [ChEBI] synonym: "serine(threonine) protein kinase inhibitor" RELATED [ChEBI] synonym: "serine(threonine) protein kinase inhibitors" RELATED [ChEBI] synonym: "serine-specific protein kinase inhibitor" RELATED [ChEBI] synonym: "serine-specific protein kinase inhibitors" RELATED [ChEBI] synonym: "serine/threonine protein kinase inhibitor" RELATED [ChEBI] synonym: "serine/threonine protein kinase inhibitors" RELATED [ChEBI] synonym: "STK32 inhibitor" RELATED [ChEBI] synonym: "STK32 inhibitors" RELATED [ChEBI] synonym: "T-antigen kinase inhibitor" RELATED [ChEBI] synonym: "T-antigen kinase inhibitors" RELATED [ChEBI] synonym: "threonine-specific protein kinase inhibitor" RELATED [ChEBI] synonym: "threonine-specific protein kinase inhibitors" RELATED [ChEBI] synonym: "twitchin kinase inhibitor" RELATED [ChEBI] synonym: "twitchin kinase inhibitors" RELATED [ChEBI] synonym: "type-2 casein kinase inhibitor" RELATED [ChEBI] synonym: "type-2 casein kinase inhibitors" RELATED [ChEBI] synonym: "Wee 1-like kinase inhibitor" RELATED [ChEBI] synonym: "Wee 1-like kinase inhibitors" RELATED [ChEBI] synonym: "Wee-kinase inhibitor" RELATED [ChEBI] synonym: "Wee-kinase inhibitors" RELATED [ChEBI] synonym: "WEE1Hu inhibitor" RELATED [ChEBI] synonym: "WEE1Hu inhibitors" RELATED [ChEBI] is_a: CHEBI:76812 ! EC 2.7.11.* (protein-serine/threonine kinase) inhibitor [Term] id: CHEBI:50929 name: aziridinium namespace: chebi_ontology subset: 3_STAR synonym: "aziridinium" EXACT IUPAC_NAME [IUPAC] synonym: "aziridinium ion" RELATED [ChEBI] xref: Gmelin:322803 {source="Gmelin"} is_a: CHEBI:37949 ! azacycloalkane is_a: CHEBI:50946 ! aziridinium ion relationship: is_conjugate_acid_of CHEBI:30969 ! aziridine property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H6N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NOWKCMXCCJGMRR-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.07578" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.04948" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1C[NH2+]1" xsd:string [Term] id: CHEBI:50930 name: thioxanthenes namespace: chebi_ontology def: "Thioxanthene and its substitution derivatives." [] subset: 3_STAR is_a: CHEBI:26979 ! organic heterotricyclic compound is_a: CHEBI:38106 ! organosulfur heterocyclic compound [Term] id: CHEBI:50946 name: aziridinium ion namespace: chebi_ontology def: "Compounds containing an aziridine ring that contains a quaternary nitrogen atom." [] subset: 3_STAR synonym: "aziridinium ions" RELATED [ChEBI] is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:50996 name: tertiary amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups." [] subset: 3_STAR synonym: "tertiary amino compounds" RELATED [ChEBI] is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_base_of CHEBI:137982 ! tertiary ammonium ion [Term] id: CHEBI:51052 name: lucanthone namespace: chebi_ontology alt_id: CHEBI:19039 alt_id: CHEBI:6552 def: "A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone." [] subset: 3_STAR synonym: "1-((2-(diethylamino)ethyl)amino)-4-methylthioxanthen-9-one" RELATED [ChemIDplus] synonym: "1-diethylaminoethylethylamino-4-methyl-thioxanthenone" RELATED [ChEBI] synonym: "1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one" EXACT IUPAC_NAME [IUPAC] synonym: "1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one" RELATED [ChEBI] synonym: "Lucanthone" EXACT [KEGG_COMPOUND] synonym: "lucanthone" RELATED INN [WHO_MedNet] synonym: "lucanthone" RELATED INN [ChemIDplus] synonym: "lucanthonum" RELATED INN [ChemIDplus] synonym: "lucantona" RELATED INN [ChemIDplus] xref: Beilstein:312369 {source="Beilstein"} xref: CAS:479-50-5 {source="ChemIDplus"} xref: CAS:479-50-5 {source="KEGG COMPOUND"} xref: Drug_Central:1616 {source="DrugCentral"} xref: DrugBank:DB04967 xref: HMDB:HMDB0015607 xref: KEGG:C11715 xref: PMID:21148553 {source="Europe PMC"} xref: PMID:21935361 {source="Europe PMC"} xref: PMID:4368942 {source="Europe PMC"} xref: PMID:6887199 {source="Europe PMC"} xref: PMID:9169823 {source="Europe PMC"} xref: Reaxys:312369 {source="Reaxys"} xref: Wikipedia:Lucanthone is_a: CHEBI:50930 ! thioxanthenes is_a: FBcv:0000551 ! enzyme inhibitor is_a: FBcv:0000569 ! lucanthone equivalent_to: FBcv:0000569 ! lucanthone relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:35610 ! antineoplastic agent relationship: has_role CHEBI:38941 ! schistosomicide drug relationship: has_role CHEBI:47868 ! photosensitizing agent relationship: has_role CHEBI:50266 ! prodrug relationship: has_role CHEBI:50276 ! EC 5.99.1.2 (DNA topoisomerase) inhibitor relationship: has_role CHEBI:50750 ! EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor relationship: has_role CHEBI:60809 ! adjuvant property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C20H24N2OS" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C20H24N2OS/c1-4-22(5-2)13-12-21-16-11-10-14(3)20-18(16)19(23)15-8-6-7-9-17(15)24-20/h6-11,21H,4-5,12-13H2,1-3H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FBQPGGIHOFZRGH-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "340.48200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "340.16093" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(CC)CCNc1ccc(C)c2sc3ccccc3c(=O)c12" xsd:string [Term] id: CHEBI:51061 name: hormone receptor modulator namespace: chebi_ontology def: "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." [] subset: 3_STAR synonym: "hormone receptor modulators" RELATED [ChEBI] is_a: CHEBI:90710 ! receptor modulator [Term] id: CHEBI:51067 name: tetraphenes namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:33836 ! benzenoid aromatic compound [Term] id: CHEBI:51069 name: organic halide salt namespace: chebi_ontology subset: 3_STAR synonym: "organic halide salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt [Term] id: CHEBI:51070 name: Janus Green B cation namespace: chebi_ontology subset: 3_STAR synonym: "3-(diethylamino)-7-{(E)-[4-(dimethylamino)phenyl]diazenyl}-5-phenylphenazin-5-ium" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:9234599 {source="Beilstein"} is_a: CHEBI:39201 ! phenazines property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C30H31N6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C30H31N6/c1-5-35(6-2)26-17-19-28-30(21-26)36(25-10-8-7-9-11-25)29-20-23(14-18-27(29)31-28)33-32-22-12-15-24(16-13-22)34(3)4/h7-21H,5-6H2,1-4H3/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "TYOFQDFFFPHHNT-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "475.60758" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "475.26047" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(CC)c1ccc2nc3ccc(cc3[n+](-c3ccccc3)c2c1)\\N=N\\c1ccc(cc1)N(C)C" xsd:string [Term] id: CHEBI:51086 name: chemical role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a chemical context." [] subset: 3_STAR is_a: CHEBI:50906 ! role [Term] id: CHEBI:51143 name: nitrogen molecular entity namespace: chebi_ontology alt_id: CHEBI:25556 alt_id: CHEBI:7594 subset: 3_STAR synonym: "nitrogen compounds" RELATED [ChEBI] synonym: "nitrogen molecular entities" RELATED [ChEBI] synonym: "Nitrogenous compounds" RELATED [KEGG_COMPOUND] xref: KEGG:C06061 is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_part CHEBI:25555 ! nitrogen atom [Term] id: CHEBI:51144 name: nitrogen group namespace: chebi_ontology subset: 3_STAR synonym: "nitrogen group" EXACT [ChEBI] synonym: "nitrogen groups" RELATED [ChEBI] synonym: "nitrogen-containing group" RELATED [ChEBI] synonym: "nitrogenous group" RELATED [ChEBI] is_a: CHEBI:24433 ! group [Term] id: CHEBI:51151 name: dipolar compound namespace: chebi_ontology def: "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." [] subset: 3_STAR synonym: "dipolar compounds" RELATED [ChEBI] is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:51214 name: diamminedichloroplatinum namespace: chebi_ontology subset: 3_STAR synonym: "diammine(dichloro)platinum" RELATED [ChEBI] synonym: "diamminedichloridoplatinum" EXACT IUPAC_NAME [IUPAC] synonym: "diamminedichloridoplatinum(II)" EXACT IUPAC_NAME [IUPAC] synonym: "diamminedichloroplatinum" EXACT IUPAC_NAME [IUPAC] synonym: "diamminedichloroplatinum(II)" EXACT IUPAC_NAME [IUPAC] synonym: "diammineplatinum dichloride" RELATED [NIST_Chemistry_WebBook] xref: CAS:14913-33-8 {source="NIST Chemistry WebBook"} xref: Gmelin:101110 {source="Gmelin"} is_a: CHEBI:33862 ! platinum coordination entity property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Cl2H6N2Pt" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "300.045" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "298.95559" xsd:string [Term] id: CHEBI:51336 name: metal sulfate namespace: chebi_ontology def: "Sulfate salts where the cation is a metal ion." [] subset: 3_STAR synonym: "metal sulfates" RELATED [ChEBI] is_a: CHEBI:24840 ! inorganic sulfate salt [Term] id: CHEBI:51348 name: tetraphene namespace: chebi_ontology alt_id: CHEBI:33088 alt_id: CHEBI:34557 def: "An angular ortho-fused polycyclic arene consisting of four fused benzene rings." [] subset: 3_STAR synonym: "1,2-Benzanthracene" RELATED [KEGG_COMPOUND] synonym: "1,2-Benzanthrazen" RELATED [ChemIDplus] synonym: "2,3-benzphenanthrene" RELATED [ChemIDplus] synonym: "Benz[a]anthracene" RELATED [KEGG_COMPOUND] synonym: "benzanthrene" RELATED [NIST_Chemistry_WebBook] synonym: "naphthanthracene" RELATED [ChemIDplus] synonym: "tetraphene" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:1909298 {source="Beilstein"} xref: CAS:56-55-3 {source="ChemIDplus"} xref: CAS:56-55-3 {source="NIST Chemistry WebBook"} xref: CAS:56-55-3 {source="KEGG COMPOUND"} xref: Gmelin:244702 {source="Gmelin"} xref: KEGG:C14317 xref: Patent:DE481819 xref: Patent:DE486766 xref: PMID:25528193 {source="Europe PMC"} xref: PMID:25528488 {source="Europe PMC"} xref: PMID:26720419 {source="Europe PMC"} xref: PMID:7561049 {source="Europe PMC"} xref: Reaxys:1909298 {source="Reaxys"} xref: Wikipedia:Tetraphene is_a: CHEBI:35296 ! ortho-fused polycyclic arene is_a: CHEBI:51067 ! tetraphenes property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C18H12" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C18H12/c1-2-7-15-12-18-16(11-14(15)6-1)10-9-13-5-3-4-8-17(13)18/h1-12H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DXBHBZVCASKNBY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "228.28788" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "228.09390" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "c1ccc2cc3c(ccc4ccccc34)cc2c1" xsd:string [Term] id: CHEBI:51422 name: organodiyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." [] subset: 3_STAR synonym: "organodiyl groups" RELATED [ChEBI] is_a: CHEBI:51446 ! organic divalent group [Term] id: CHEBI:51446 name: organic divalent group namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51447 name: organic univalent group namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51569 name: N-acyl-amino acid namespace: chebi_ontology alt_id: CHEBI:21653 alt_id: CHEBI:22226 def: "A carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of an amino acid." [] subset: 3_STAR synonym: "acyl-amino-acid" RELATED [ChEBI] synonym: "acyl-amino-acids" RELATED [ChEBI] synonym: "acylamino acids" RELATED [ChEBI] synonym: "N-acyl amino acid" RELATED [ChEBI] synonym: "N-acyl amino acids" RELATED [ChEBI] synonym: "N-acyl-amino-acid" RELATED [ChEBI] synonym: "N-acyl-amino-acids" RELATED [ChEBI] synonym: "N-acylamino acid" RELATED [ChEBI] synonym: "N-acylamino acids" RELATED [ChEBI] is_a: CHEBI:33575 ! carboxylic acid is_a: CHEBI:37622 ! carboxamide is_a: CHEBI:83821 ! amino acid derivative relationship: has_functional_parent CHEBI:33709 ! amino acid [Term] id: CHEBI:51803 name: aminoacridines namespace: chebi_ontology def: "Acridines which are substituted in any position by one or more amino groups or substituted amino groups. Note that the term 'aminoacridine' is the International Prorietary Name (INN) for 9-aminoacridine." [] subset: 3_STAR synonym: "aminoacridine" RELATED [ChEBI] is_a: CHEBI:22213 ! acridines [Term] id: CHEBI:51958 name: organic polycyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:51959 name: organic tricyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic tricyclic compounds" RELATED [ChEBI] is_a: CHEBI:51958 ! organic polycyclic compound [Term] id: CHEBI:52206 name: biochemical role namespace: chebi_ontology def: "A biological role played by the molecular entity or part thereof within a biochemical context." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52208 name: biophysical role namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52209 name: aetiopathogenetic role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." [] subset: 3_STAR synonym: "etiopathogenetic agent" RELATED [ChEBI] synonym: "etiopathogenetic role" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52210 name: pharmacological role namespace: chebi_ontology def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52211 name: physiological role namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52217 name: pharmaceutical namespace: chebi_ontology alt_id: CHEBI:33293 alt_id: CHEBI:33294 def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." [] subset: 3_STAR synonym: "farmaco" RELATED [ChEBI] synonym: "medicament" RELATED [ChEBI] synonym: "pharmaceuticals" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:52684 name: butanediol namespace: chebi_ontology def: "A member of the class of butanediols that is butane in which two of the hydrogens have been replaced by hydroxy groups." [] subset: 3_STAR synonym: "butanediol" EXACT IUPAC_NAME [IUPAC] synonym: "butanediols" RELATED [ChEBI] is_a: CHEBI:22944 ! butanediols relationship: has_parent_hydride CHEBI:37808 ! butane [Term] id: CHEBI:52768 name: hycanthone namespace: chebi_ontology def: "A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel." [] subset: 3_STAR synonym: "1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one" RELATED [ChemIDplus] synonym: "1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one" RELATED [ChemIDplus] synonym: "1-(2-diethylaminoethylamino)-4-(hydroxymethyl)thioxanthen-9-one" RELATED [ChEBI] synonym: "1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one" EXACT IUPAC_NAME [IUPAC] synonym: "hicantona" RELATED INN [ChemIDplus] synonym: "Hycanthon" RELATED [ChemIDplus] synonym: "Hycanthone" EXACT [KEGG_DRUG] synonym: "hycanthone" RELATED INN [WHO_MedNet] synonym: "hycanthone" RELATED INN [KEGG_DRUG] synonym: "hycanthonum" RELATED INN [ChemIDplus] synonym: "Lucanthone metabolite" RELATED [ChemIDplus] xref: Beilstein:1402722 {source="Beilstein"} xref: CAS:3105-97-3 {source="KEGG DRUG"} xref: CAS:3105-97-3 {source="ChemIDplus"} xref: Drug_Central:1383 {source="DrugCentral"} xref: KEGG:D00541 xref: LINCS:LSM-5614 xref: Patent:NL6410359 xref: Patent:US3294803 xref: Patent:US3312598 xref: PMID:1888160 {source="Europe PMC"} xref: PMID:21935361 {source="Europe PMC"} xref: PMID:2957147 {source="Europe PMC"} xref: PMID:5573958 {source="Europe PMC"} xref: PMID:626982 {source="Europe PMC"} xref: PMID:7369442 {source="Europe PMC"} xref: Reaxys:1402722 {source="Reaxys"} xref: Wikipedia:Hycanthone is_a: BFO:0000004 ! independent continuant is_a: CHEBI:50930 ! thioxanthenes relationship: has_functional_parent CHEBI:51052 ! lucanthone relationship: has_role CHEBI:25435 ! mutagen relationship: has_role CHEBI:38941 ! schistosomicide drug relationship: is_conjugate_base_of CHEBI:67141 ! hycanthone(1+) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C20H24N2O2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C20H24N2O2S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20/h5-10,21,23H,3-4,11-13H2,1-2H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MFZWMTSUNYWVBU-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "356.48200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "356.15585" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12" xsd:string [Term] id: CHEBI:53121 name: adenosine A2A receptor antagonist namespace: chebi_ontology def: "An antagonist at the A2A receptor." [] subset: 3_STAR synonym: "adenosine A2A receptor antagonists" RELATED [ChEBI] xref: Wikipedia:Adenosine_A2A_receptor is_a: CHEBI:71232 ! adenosine receptor antagonist [Term] id: CHEBI:53526 name: tritiated thymidine namespace: chebi_ontology def: "Thymidine linked to the radioisotope tritium. Used to label DNA in the study of cellular and viral DNA synthesis." [] subset: 3_STAR synonym: "(3)HTdR" RELATED [ChEBI] synonym: "(3H)Thymidine" RELATED [ChemIDplus] synonym: "Thymidine-(H-3)" RELATED [ChemIDplus] synonym: "tritiated thymidines" RELATED [ChEBI] xref: CAS:50-88-4 {source="ChemIDplus"} is_a: CHEBI:139359 ! tritiated compound is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside is_a: FBcv:0000513 ! 3H-thymidine equivalent_to: FBcv:0000513 ! 3H-thymidine relationship: has_functional_parent CHEBI:17748 ! thymidine [Term] id: CHEBI:5686 name: heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of at least two different elements." [] subset: 3_STAR synonym: "compuesto heterociclico" RELATED [IUPAC] synonym: "compuestos heterociclicos" RELATED [IUPAC] synonym: "heterocycle" RELATED [ChEBI] synonym: "Heterocyclic compound" EXACT [KEGG_COMPOUND] synonym: "heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:57981 name: D-phenylalanine zwitterion namespace: chebi_ontology def: "A D-alpha-amino acid zwitterion that is D-phenylalanine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." [] subset: 3_STAR synonym: "(2R)-2-ammonio-3-phenylpropanoate" RELATED [IUPAC] synonym: "(2R)-2-azaniumyl-3-phenylpropanoate" EXACT IUPAC_NAME [IUPAC] synonym: "D-phenylalanine" RELATED [UniProt] xref: MetaCyc:CPD-216 is_a: CHEBI:59871 ! D-alpha-amino acid zwitterion relationship: is_enantiomer_of CHEBI:58095 ! L-phenylalanine zwitterion relationship: is_tautomer_of CHEBI:16998 ! D-phenylalanine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H11NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-MRVPVSSYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "165.18910" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "165.07898" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@H](Cc1ccccc1)C([O-])=O" xsd:string [Term] id: CHEBI:58095 name: L-phenylalanine zwitterion namespace: chebi_ontology def: "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-phenylalanine; major species at pH 7.3." [] subset: 3_STAR synonym: "(2S)-2-ammonio-3-phenylpropanoate" RELATED [IUPAC] synonym: "(2S)-2-azaniumyl-3-phenylpropanoate" EXACT IUPAC_NAME [IUPAC] synonym: "L-phenylalanine" RELATED [UniProt] synonym: "phenylalanine" RELATED [ChEBI] xref: MetaCyc:PHE xref: PMID:21956539 {source="Europe PMC"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_enantiomer_of CHEBI:57981 ! D-phenylalanine zwitterion relationship: is_tautomer_of CHEBI:17295 ! L-phenylalanine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C9H11NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "COLNVLDHVKWLRT-QMMMGPOBSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "165.18910" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "165.07898" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@@H](Cc1ccccc1)C([O-])=O" xsd:string [Term] id: CHEBI:58951 name: short-chain fatty acid anion namespace: chebi_ontology def: "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." [] subset: 3_STAR synonym: "a short-chain fatty acid" RELATED [UniProt] synonym: "short-chain fatty acid anions" RELATED [ChEBI] is_a: CHEBI:28868 ! fatty acid anion relationship: is_conjugate_base_of CHEBI:26666 ! short-chain fatty acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:58953 name: saturated fatty acid anion namespace: chebi_ontology def: "Any fatty acid anion in which there is no C-C unsaturation." [] subset: 3_STAR synonym: "saturated fatty acid anions" RELATED [ChEBI] is_a: CHEBI:28868 ! fatty acid anion [Term] id: CHEBI:58954 name: straight-chain saturated fatty acid anion namespace: chebi_ontology def: "Any saturated fatty acid anion lacking a carbon side-chain." [] subset: 3_STAR synonym: "straight-chain saturated fatty acid anions" RELATED [ChEBI] is_a: CHEBI:58953 ! saturated fatty acid anion relationship: is_conjugate_base_of CHEBI:39418 ! straight-chain saturated fatty acid [Term] id: CHEBI:58958 name: organosulfate oxoanion namespace: chebi_ontology def: "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." [] subset: 3_STAR synonym: "organosulfate oxoanions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:33482 ! sulfur oxoanion relationship: has_functional_parent CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:25704 ! organic sulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:59202 name: straight-chain fatty acid namespace: chebi_ontology def: "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." [] subset: 3_STAR synonym: "straight-chain fatty acids" RELATED [ChEBI] is_a: CHEBI:35366 ! fatty acid relationship: is_conjugate_acid_of CHEBI:59203 ! straight-chain fatty acid anion [Term] id: CHEBI:59203 name: straight-chain fatty acid anion namespace: chebi_ontology def: "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." [] subset: 3_STAR synonym: "straight-chain FA anion" RELATED [ChEBI] synonym: "straight-chain FA anions" RELATED [ChEBI] synonym: "straight-chain fatty acid anions" RELATED [ChEBI] is_a: CHEBI:28868 ! fatty acid anion relationship: is_conjugate_base_of CHEBI:59202 ! straight-chain fatty acid [Term] id: CHEBI:59698 name: phosphoric acids namespace: chebi_ontology def: "Compounds containing one or more phosphoric acid units." [] subset: 3_STAR is_a: CHEBI:33457 ! phosphorus oxoacid [Term] id: CHEBI:59740 name: nucleophilic reagent namespace: chebi_ontology def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." [] subset: 3_STAR synonym: "nucleophile" RELATED [ChEBI] synonym: "nucleophiles" RELATED [ChEBI] synonym: "nucleophilic reagents" RELATED [ChEBI] is_a: CHEBI:33893 ! reagent is_a: CHEBI:39144 ! Lewis base [Term] id: CHEBI:59765 name: boric acids namespace: chebi_ontology def: "Hydroxy boron compounds of general formula BxOyHz." [] subset: 3_STAR is_a: CHEBI:33145 ! boron oxoacid relationship: has_role CHEBI:138103 ! inorganic acid [Term] id: CHEBI:59814 name: L-alpha-amino acid anion namespace: chebi_ontology def: "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." [] subset: 3_STAR synonym: "L-alpha-amino carboxylate" RELATED [ChEBI] is_a: CHEBI:33558 ! alpha-amino-acid anion relationship: is_conjugate_base_of CHEBI:15705 ! L-alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "73.051" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "73.01638" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C@H](C(=O)[O-])(N)*" xsd:string [Term] id: CHEBI:59869 name: L-alpha-amino acid zwitterion namespace: chebi_ontology def: "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group." [] subset: 3_STAR synonym: "an L-alpha-amino acid" RELATED [UniProt] synonym: "L-alpha-amino acid zwitterions" RELATED [ChEBI] is_a: CHEBI:78608 ! alpha-amino acid zwitterion relationship: is_tautomer_of CHEBI:15705 ! L-alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@@H]([*])C([O-])=O" xsd:string [Term] id: CHEBI:59871 name: D-alpha-amino acid zwitterion namespace: chebi_ontology def: "Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group." [] subset: 3_STAR synonym: "a D-alpha-amino acid" RELATED [UniProt] synonym: "D-alpha-amino acid zwitterions" RELATED [ChEBI] is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_tautomer_of CHEBI:16733 ! D-alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][C@H]([*])C([O-])=O" xsd:string [Term] id: CHEBI:59874 name: N-acyl-L-alpha-amino acid anion namespace: chebi_ontology def: "A carboxylic acid anion that is the conjugate base of an N-acyl-L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." [] subset: 3_STAR synonym: "an N-acyl-L-amino acid" RELATED [UniProt] synonym: "N-acyl-L-alpha-amino acid(1-)" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: has_functional_parent CHEBI:59814 ! L-alpha-amino acid anion relationship: is_conjugate_base_of CHEBI:48927 ! N-acyl-L-alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H2NO3R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "100.05290" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "100.00347" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C(=O)[C@H]([*])NC([*])=O" xsd:string [Term] id: CHEBI:59876 name: N-acyl-D-alpha-amino acid anion namespace: chebi_ontology def: "The conjugate base of an N-acyl-D-alpha-amino acid arising from deprotonation of the C-1 carboxy group." [] subset: 3_STAR synonym: "an N-acyl-D-amino acid" RELATED [UniProt] synonym: "N-acyl-D-alpha-amino acid(1-)" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:15778 ! N-acyl-D-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C3H2NO3R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "100.05290" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "100.00347" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C(=O)[C@@H]([*])NC([*])=O" xsd:string [Term] id: CHEBI:59897 name: EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor namespace: chebi_ontology def: "A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce." [] subset: 3_STAR synonym: "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitor" RELATED [ChEBI] synonym: "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitors" RELATED [ChEBI] synonym: "DNA nucleotidyltransferase (RNA-directed) inhibitor" RELATED [ChEBI] synonym: "DNA nucleotidyltransferase (RNA-directed) inhibitors" RELATED [ChEBI] synonym: "EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitors" RELATED [ChEBI] synonym: "EC 2.7.7.49 inhibitor" RELATED [ChEBI] synonym: "EC 2.7.7.49 inhibitors" RELATED [ChEBI] synonym: "reverse transcriptase inhibitor" RELATED [ChEBI] synonym: "reverse transcriptase inhibitors" RELATED [ChEBI] synonym: "revertase inhibitor" RELATED [ChEBI] synonym: "revertase inhibitors" RELATED [ChEBI] synonym: "RNA revertase inhibitor" RELATED [ChEBI] synonym: "RNA revertase inhibitors" RELATED [ChEBI] synonym: "RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitor" RELATED [ChEBI] synonym: "RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitors" RELATED [ChEBI] synonym: "RNA-dependent DNA polymerase inhibitor" RELATED [ChEBI] synonym: "RNA-dependent DNA polymerase inhibitors" RELATED [ChEBI] synonym: "RNA-directed DNA polymerase (EC 2.7.7.49) inhibitor" RELATED [ChEBI] synonym: "RNA-directed DNA polymerase (EC 2.7.7.49) inhibitors" RELATED [ChEBI] synonym: "RNA-directed DNA polymerase inhibitor" RELATED [ChEBI] synonym: "RNA-directed DNA polymerase inhibitors" RELATED [ChEBI] synonym: "RNA-instructed DNA polymerase inhibitor" RELATED [ChEBI] synonym: "RNA-instructed DNA polymerase inhibitors" RELATED [ChEBI] synonym: "RT inhibitor" RELATED [ChEBI] synonym: "RT inhibitors" RELATED [ChEBI] synonym: "telomerase inhibitor" RELATED [ChEBI] synonym: "telomerase inhibitors" RELATED [ChEBI] xref: Wikipedia:Reverse-transcriptase_inhibitor is_a: CHEBI:22587 ! antiviral agent is_a: CHEBI:38234 ! DNA polymerase inhibitor [Term] id: CHEBI:60038 name: flavonoid oxoanion namespace: chebi_ontology def: "Any anion arising from deprotonation of at least one OH group in a flavonoid compound." [] subset: 3_STAR synonym: "flavonoid oxoanions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion [Term] id: CHEBI:60240 name: divalent metal cation namespace: chebi_ontology def: "A metal cation with a valence of two." [] subset: 3_STAR synonym: "a divalent metal cation" RELATED [UniProt] is_a: CHEBI:25213 ! metal cation is_a: CHEBI:64641 ! divalent inorganic cation [Term] id: CHEBI:60242 name: monovalent inorganic cation namespace: chebi_ontology def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." [] subset: 3_STAR synonym: "a monovalent cation" RELATED [UniProt] is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:60251 name: guanidinium ion namespace: chebi_ontology def: "R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives." [] subset: 3_STAR synonym: "diaminomethaniminium ion" RELATED [ChEBI] synonym: "diaminomethaniminium ions" RELATED [ChEBI] synonym: "guanidinium ions" RELATED [ChEBI] is_a: CHEBI:35286 ! iminium ion property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHN3R5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "55.039" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "55.01705" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(=[N+]([H])*)(N(*)*)N(*)*" xsd:string [Term] id: CHEBI:60466 name: peptide zwitterion namespace: chebi_ontology def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." [] subset: 3_STAR synonym: "peptide zwitterions" RELATED [ChEBI] is_a: CHEBI:27369 ! zwitterion relationship: is_tautomer_of CHEBI:16670 ! peptide property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R(C2H2NOR)n" xsd:string [Term] id: CHEBI:60809 name: adjuvant namespace: chebi_ontology def: "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." [] subset: 3_STAR synonym: "adjuvants" RELATED [ChEBI] is_a: CHEBI:52217 ! pharmaceutical [Term] id: CHEBI:60832 name: tubulin modulator namespace: chebi_ontology def: "Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules." [] subset: 3_STAR synonym: "tubulin modulators" RELATED [ChEBI] is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:60895 name: D-alpha-amino acid anion namespace: chebi_ontology def: "Any alpha-amino acid anion in which the parent amino acid has D-configuration." [] subset: 3_STAR synonym: "D-alpha-amino acid anions" RELATED [ChEBI] synonym: "D-alpha-amino carboxylate" RELATED [ChEBI] is_a: CHEBI:33558 ! alpha-amino-acid anion relationship: is_conjugate_base_of CHEBI:16733 ! D-alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "73.051" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "73.01638" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C@@H](C(=O)[O-])(N)*" xsd:string [Term] id: CHEBI:61015 name: nephrotoxin namespace: chebi_ontology def: "A poison that interferes with the function of the kidneys." [] subset: 3_STAR synonym: "nephrotoxins" RELATED [ChEBI] is_a: CHEBI:64909 ! poison [Term] id: CHEBI:61120 name: nucleobase-containing molecular entity namespace: chebi_ontology def: "Any compound that has a nucleobase as a part." [] subset: 3_STAR synonym: "nucleobase-containing compound" RELATED [SUBMITTER] synonym: "nucleobase-containing compounds" RELATED [ChEBI] synonym: "nucleobase-containing molecular entities" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_functional_parent CHEBI:18282 ! nucleobase [Term] id: CHEBI:61249 name: hesperetin(1-) namespace: chebi_ontology def: "A flavonoid oxoanion that is the conjugate base of hesperetin arising from selective deprtotonation of the 7-hydroxy group." [] subset: 3_STAR synonym: "(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxochroman-7-olate" EXACT IUPAC_NAME [IUPAC] synonym: "hesperetin anion" RELATED [ChEBI] xref: MetaCyc:CPD-7072 {source="SUBMITTER"} is_a: CHEBI:60038 ! flavonoid oxoanion relationship: is_conjugate_base_of CHEBI:28230 ! hesperetin property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C16H13O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3/p-1/t14-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "AIONOLUJZLIMTK-AWEZNQCLSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "301.27080" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "301.07176" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O)cc([O-])cc2O1" xsd:string [Term] id: CHEBI:616459 name: carbamimidoylazanium namespace: chebi_ontology subset: 2_STAR is_a: CHEBI:35359 ! carboxamidine relationship: is_conjugate_base_of CHEBI:30087 ! guanidinium [Term] id: CHEBI:61951 name: microtubule-destabilising agent namespace: chebi_ontology def: "Any substance that interacts with tubulin to inhibit polymerisation of microtubules." [] subset: 3_STAR synonym: "microtubule destabilising agent" RELATED [ChEBI] synonym: "microtubule destabilising agents" RELATED [ChEBI] synonym: "microtubule destabilising role" RELATED [ChEBI] synonym: "microtubule destabilizing role" RELATED [SUBMITTER] synonym: "microtubule-destabilising agents" RELATED [ChEBI] synonym: "microtubule-destabilizing agent" RELATED [ChEBI] synonym: "microtubule-destabilizing agents" RELATED [ChEBI] xref: PMID:17099073 {source="Europe PMC"} is_a: CHEBI:60832 ! tubulin modulator is_a: CHEBI:64911 ! antimitotic [Term] id: CHEBI:62031 name: polar amino acid zwitterion namespace: chebi_ontology def: "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." [] subset: 2_STAR synonym: "a polar amino acid" RELATED [UniProt] xref: MetaCyc:Polar-amino-acids {source="SUBMITTER"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_tautomer_of CHEBI:26167 ! polar amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(C([O-])=O)(*)[NH3+]" xsd:string [Term] id: CHEBI:62081 name: 1,1-diunsubstituted alkanesulfonate namespace: chebi_ontology def: "An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens." [] subset: 3_STAR synonym: "1,1-di-unsubstituted alkanesulfonate" RELATED [ChEBI] synonym: "1,1-di-unsubstituted alkanesulfonates" RELATED [ChEBI] synonym: "1,1-diunsubstituted alkanesulfonates" RELATED [ChEBI] xref: KEGG:C15521 xref: MetaCyc:Alkanesulfonates is_a: BFO:0000004 ! independent continuant is_a: CHEBI:134249 ! alkanesulfonate oxoanion relationship: has_role CHEBI:35703 ! xenobiotic property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O3SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "94.09000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "93.97246" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]C([H])([*])S([O-])(=O)=O" xsd:string [Term] id: CHEBI:62501 name: folate(2-) namespace: chebi_ontology def: "The dicarboxylic acid dianion formed from folic acid by loss of a proton from each of the two carboxy groups in the glutamic acid moiety." [] subset: 3_STAR synonym: "folate" RELATED [UniProt] synonym: "folate" RELATED [MetaCyc] synonym: "N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "pteroyl-L-glutamate" RELATED [ChEBI] synonym: "pteroyl-L-monoglutamate" RELATED [ChEBI] synonym: "pteroylglutamate" RELATED [ChEBI] xref: MetaCyc:CPD-12826 {source="SUBMITTER"} xref: PMCID:PMC8181341 {source="Europe PMC"} xref: PMID:34051149 {source="Europe PMC"} is_a: CHEBI:28965 ! dicarboxylic acid dianion is_a: CHEBI:67011 ! folates relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: is_conjugate_base_of CHEBI:27470 ! folic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H17N7O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/p-2/t12-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OVBPIULPVIDEAO-LBPRGKRZSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "439.38160" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "439.12513" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Nc1nc2ncc(CNc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)nc2c(=O)[nH]1" xsd:string [Term] id: CHEBI:62803 name: fuel additive namespace: chebi_ontology def: "Any additive that enhances the efficiency of fuel." [] subset: 3_STAR synonym: "fuel additives" RELATED [ChEBI] synonym: "fuel enhancer" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:63161 name: glycosyl compound namespace: chebi_ontology def: "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity." [] subset: 3_STAR synonym: "glycosyl compounds" RELATED [ChEBI] is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:63299 name: carbohydrate derivative namespace: chebi_ontology def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." [] subset: 3_STAR synonym: "carbohydrate derivatives" RELATED [ChEBI] synonym: "derivatised carbohydrate" RELATED [ChEBI] synonym: "derivatised carbohydrates" RELATED [ChEBI] synonym: "derivatized carbohydrate" RELATED [ChEBI] synonym: "derivatized carbohydrates" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives relationship: has_functional_parent CHEBI:16646 ! carbohydrate [Term] id: CHEBI:63332 name: EC 3.1.3.1 (alkaline phosphatase) inhibitor namespace: chebi_ontology def: "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1)." [] subset: 3_STAR synonym: "alkaline phenyl phosphatase inhibitor" RELATED [ChEBI] synonym: "alkaline phenyl phosphatase inhibitors" RELATED [ChEBI] synonym: "alkaline phosphatase (EC 3.1.3.1) inhibitor" RELATED [ChEBI] synonym: "alkaline phosphatase (EC 3.1.3.1) inhibitors" RELATED [ChEBI] synonym: "alkaline phosphatase inhibitor" RELATED [ChEBI] synonym: "alkaline phosphatase inhibitors" RELATED [ChEBI] synonym: "alkaline phosphohydrolase inhibitor" RELATED [ChEBI] synonym: "alkaline phosphohydrolase inhibitors" RELATED [ChEBI] synonym: "alkaline phosphomonoesterase inhibitor" RELATED [ChEBI] synonym: "alkaline phosphomonoesterase inhibitors" RELATED [ChEBI] synonym: "EC 3.1.3.1 (alkaline phosphatase) inhibitors" RELATED [ChEBI] synonym: "EC 3.1.3.1 inhibitor" RELATED [ChEBI] synonym: "EC 3.1.3.1 inhibitors" RELATED [ChEBI] synonym: "glycerophosphatase inhibitor" RELATED [ChEBI] synonym: "glycerophosphatase inhibitors" RELATED [ChEBI] synonym: "orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor" RELATED [ChEBI] synonym: "orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors" RELATED [ChEBI] synonym: "phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor" RELATED [ChEBI] synonym: "phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors" RELATED [ChEBI] synonym: "phosphomonoesterase inhibitor" RELATED [ChEBI] synonym: "phosphomonoesterase inhibitors" RELATED [ChEBI] xref: Wikipedia:Alkaline_phosphatase is_a: CHEBI:76775 ! EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor [Term] id: CHEBI:63353 name: disaccharide derivative namespace: chebi_ontology def: "A carbohydrate derivative that is formally obtained from a disaccharide." [] subset: 3_STAR synonym: "disaccharide derivatives" RELATED [ChEBI] is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:36233 ! disaccharide [Term] id: CHEBI:63470 name: sulfur-containing amino-acid anion namespace: chebi_ontology def: "A sulfur-containing amino acid whose alpha-carboxylic acid group is ionized (not protonated)." [] subset: 3_STAR synonym: "sulfur-containing amino-acid anions" RELATED [ChEBI] is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:26834 ! sulfur-containing amino acid [Term] id: CHEBI:63473 name: aromatic amino-acid anion namespace: chebi_ontology def: "An aromatic amino acid whose alpha-carboxylic acid group is ionized (non-protonated)." [] subset: 3_STAR synonym: "aromatic amino-acid anions" RELATED [ChEBI] is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:33856 ! aromatic amino acid [Term] id: CHEBI:63490 name: explosive namespace: chebi_ontology def: "A substance capable of undergoing rapid and highly exothermic decomposition." [] subset: 3_STAR synonym: "explosive compound" RELATED [ChEBI] synonym: "explosive compounds" RELATED [ChEBI] synonym: "explosive material" RELATED [ChEBI] synonym: "explosives" RELATED [ChEBI] synonym: "explosives chemical" RELATED [ChEBI] synonym: "explosives chemicals" RELATED [ChEBI] xref: Wikipedia:Explosive_material is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:63624 name: telbivudine namespace: chebi_ontology def: "A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase." [] subset: 3_STAR synonym: "1-(2-deoxy-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione" EXACT IUPAC_NAME [IUPAC] synonym: "1-(2-deoxy-beta-L-ribofuranosyl)-5-methyluracil" RELATED [ChEBI] synonym: "2'-Deoxy-L-thymidine" RELATED [DrugBank] synonym: "beta-L-2'-deoxythymidine" RELATED [ChEBI] synonym: "Beta-l-thymidine" RELATED [DrugBank] synonym: "Epavudine" RELATED [DrugBank] synonym: "L-deoxythymidine" RELATED [DrugBank] synonym: "L-DT" RELATED [DrugBank] synonym: "L-thymidine" RELATED [DrugBank] synonym: "LDT" RELATED [DrugBank] synonym: "telbivudine" RELATED INN [KEGG_DRUG] xref: CAS:3424-98-4 {source="ChemIDplus"} xref: Drug_Central:4220 {source="DrugCentral"} xref: DrugBank:DB01265 xref: KEGG:D06675 xref: PMID:21040410 {source="Europe PMC"} xref: PMID:21147187 {source="Europe PMC"} xref: PMID:21457439 {source="Europe PMC"} xref: PMID:21586234 {source="Europe PMC"} xref: PMID:21642814 {source="Europe PMC"} xref: PMID:21670922 {source="Europe PMC"} xref: PMID:21703206 {source="Europe PMC"} xref: PMID:21748522 {source="Europe PMC"} xref: PMID:22093034 {source="Europe PMC"} xref: PMID:22132702 {source="Europe PMC"} xref: PMID:22174039 {source="Europe PMC"} xref: PMID:22233255 {source="Europe PMC"} xref: PMID:22257108 {source="Europe PMC"} xref: Reaxys:754297 {source="Reaxys"} xref: Wikipedia:Telbivudine is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside is_a: FBcv:0000551 ! enzyme inhibitor relationship: has_functional_parent CHEBI:17821 ! thymine relationship: has_role CHEBI:36044 ! antiviral drug relationship: has_role CHEBI:59897 ! EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor relationship: is_enantiomer_of CHEBI:17748 ! thymidine property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H14N2O5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "IQFYYKKMVGJFEH-CSMHCCOUSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "242.22860" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "242.09027" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "Cc1cn([C@@H]2C[C@@H](O)[C@H](CO)O2)c(=O)[nH]c1=O" xsd:string [Term] id: CHEBI:64047 name: food additive namespace: chebi_ontology def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." [] subset: 3_STAR synonym: "food additives" RELATED [ChEBI] xref: Wikipedia:Food_additive is_a: CHEBI:33232 ! application is_a: CHEBI:78295 ! food component [Term] id: CHEBI:64382 name: organosulfonate salt namespace: chebi_ontology def: "Any organic salt prepared using an organosulfonic acid as the acid component." [] subset: 3_STAR synonym: "organosulfonate salts" RELATED [ChEBI] synonym: "organosulphonate salt" RELATED [ChEBI] synonym: "organosulphonate salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:33261 ! organosulfur compound [Term] id: CHEBI:64577 name: flour treatment agent namespace: chebi_ontology def: "A food additive which is added to flour or dough to improve baking quality and/or colour." [] subset: 3_STAR synonym: "dough improver" RELATED [ChEBI] synonym: "dough improvers" RELATED [ChEBI] synonym: "flour treatment agent" EXACT [ChEBI] synonym: "improving agent" RELATED [ChEBI] synonym: "improving agents" RELATED [ChEBI] xref: Wikipedia:Flour_treatment_agent is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:64641 name: divalent inorganic cation namespace: chebi_ontology def: "An inorganic cation with a valency of two." [] subset: 3_STAR is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:64708 name: one-carbon compound namespace: chebi_ontology def: "An organic molecular entity containing a single carbon atom (C1)." [] subset: 3_STAR synonym: "one-carbon compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64709 name: organic acid namespace: chebi_ontology def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." [] subset: 3_STAR synonym: "organic acids" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64857 name: cosmetic namespace: chebi_ontology def: "The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it." [] subset: 3_STAR synonym: "cosmetic component" RELATED [ChEBI] synonym: "cosmetics" RELATED [ChEBI] xref: Wikipedia:Cosmetics is_a: CHEBI:33232 ! application [Term] id: CHEBI:64909 name: poison namespace: chebi_ontology def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." [] subset: 3_STAR synonym: "poisonous agent" RELATED [ChEBI] synonym: "poisonous agents" RELATED [ChEBI] synonym: "poisonous substance" RELATED [ChEBI] synonym: "poisonous substances" RELATED [ChEBI] synonym: "poisons" RELATED [ChEBI] synonym: "toxic agent" RELATED [ChEBI] synonym: "toxic agents" RELATED [ChEBI] synonym: "toxic substance" RELATED [ChEBI] synonym: "toxic substances" RELATED [ChEBI] xref: Wikipedia:Poison is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:64911 name: antimitotic namespace: chebi_ontology def: "Any compound that inhibits cell division (mitosis)." [] subset: 3_STAR synonym: "antimitotics" RELATED [ChEBI] synonym: "mitosis inhibitor" RELATED [ChEBI] synonym: "mitosis inhibitors" RELATED [ChEBI] synonym: "mitotic inhibitor" RELATED [ChEBI] synonym: "mitotic inhibitors" RELATED [ChEBI] xref: Wikipedia:Mitotic_inhibitor is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:64915 name: antiplasmodial drug namespace: chebi_ontology def: "An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria." [] subset: 3_STAR synonym: "antiplasmodial agent" RELATED [ChEBI] synonym: "antiplasmodial agents" RELATED [ChEBI] synonym: "antiplasmodial drugs" RELATED [ChEBI] synonym: "antiplasmodium agent" RELATED [ChEBI] synonym: "antiplasmodium agents" RELATED [ChEBI] synonym: "antiplasmodium drug" RELATED [ChEBI] synonym: "antiplasmodium drugs" RELATED [ChEBI] is_a: CHEBI:35820 ! antiprotozoal drug [Term] id: CHEBI:67011 name: folates namespace: chebi_ontology def: "An N-acyl-L-alpha-amino acid anion obtained by deprotonation of any folic acid." [] subset: 3_STAR synonym: "folate" RELATED [ChEBI] synonym: "folate anion" RELATED [ChEBI] synonym: "folate anions" RELATED [ChEBI] is_a: CHEBI:176842 ! vitamin B9 is_a: CHEBI:59874 ! N-acyl-L-alpha-amino acid anion relationship: is_conjugate_base_of CHEBI:37445 ! folic acids [Term] id: CHEBI:67105 name: insect sterilant namespace: chebi_ontology def: "A chemosterilant intended to sterilize insects." [] subset: 3_STAR synonym: "insect chemosterilant" RELATED [ChEBI] synonym: "insect chemosterilants" RELATED [ChEBI] synonym: "insect sterilants" RELATED [ChEBI] is_a: CHEBI:23092 ! chemosterilant is_a: CHEBI:24852 ! insecticide [Term] id: CHEBI:67107 name: dimethylmyleran namespace: chebi_ontology def: "A methanesulfonate ester that is hexane-2,5-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups." [] subset: 3_STAR synonym: "1,4-bis(methylsulfonyloxy)-1,4-dimethylbutane" RELATED [ChemIDplus] synonym: "1,4-dimethanesulfonoxy-1,4-dimethylbutane" RELATED [ChemIDplus] synonym: "1,4-dimethylbusulfan" RELATED [ChEBI] synonym: "1,4-dimethylmyleran" RELATED [ChEBI] synonym: "2,5-dimethanesulfomyloxyhexane" RELATED [ChemIDplus] synonym: "2,5-hexanediol dimesylate" RELATED [ChEBI] synonym: "2,5-hexanediol dimethylsulfonate" RELATED [ChemIDplus] synonym: "dimethylbusulfan" RELATED [ChemIDplus] synonym: "DMM" RELATED [ChemIDplus] synonym: "hexane-2,5-diyl dimethanesulfonate" EXACT IUPAC_NAME [IUPAC] xref: CAS:55-93-6 {source="ChemIDplus"} xref: PMID:3800321 {source="Europe PMC"} xref: Reaxys:1796040 {source="Reaxys"} is_a: CHEBI:25223 ! methanesulfonate ester is_a: FBcv:0000526 ! alkylating agent is_a: FBcv:0000563 ! 1,4-dimethanesulfonoxy-1,4-dimethylbutane equivalent_to: FBcv:0000563 ! 1,4-dimethanesulfonoxy-1,4-dimethylbutane relationship: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:25435 ! mutagen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H18O6S2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H18O6S2/c1-7(13-15(3,9)10)5-6-8(2)14-16(4,11)12/h7-8H,5-6H2,1-4H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "JDZNTUQRMDAIRO-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "274.35500" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "274.05448" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(CCC(C)OS(C)(=O)=O)OS(C)(=O)=O" xsd:string [Term] id: CHEBI:67114 name: ryanodine receptor agonist namespace: chebi_ontology def: "A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction." [] subset: 3_STAR synonym: "ryanodine receptor activator" RELATED [ChEBI] synonym: "ryanodine receptor activators" RELATED [ChEBI] synonym: "RyR activator" RELATED [ChEBI] synonym: "RyR activators" RELATED [ChEBI] synonym: "RyR agonist" RELATED [ChEBI] synonym: "RyR agonists" RELATED [ChEBI] synonym: "RyRs activator" RELATED [ChEBI] synonym: "RyRs agonist" RELATED [ChEBI] xref: PMID:30679133 {source="Europe PMC"} xref: PMID:30684528 {source="Europe PMC"} xref: PMID:31840405 {source="Europe PMC"} xref: PMID:8597061 {source="Europe PMC"} xref: Wikipedia:Ryanodine_receptor is_a: CHEBI:38809 ! ryanodine receptor modulator [Term] id: CHEBI:67141 name: hycanthone(1+) namespace: chebi_ontology def: "An ammonium ion resulting from the protonation of the tertiary amino group of lycanthone." [] subset: 3_STAR synonym: "N,N-diethyl-2-{[4-(hydroxymethyl)-10-oxo-10H-dibenzo[b,e]thiopyran-1-yl]amino}ethanaminium" EXACT IUPAC_NAME [IUPAC] xref: Reaxys:19574704 {source="Reaxys"} is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:52768 ! hycanthone property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C20H25N2O2S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C20H24N2O2S/c1-3-22(4-2)12-11-21-16-10-9-14(13-23)20-18(16)19(24)15-7-5-6-8-17(15)25-20/h5-10,21,23H,3-4,11-13H2,1-2H3/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MFZWMTSUNYWVBU-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "357.49000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "357.16313" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC[NH+](CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12" xsd:string [Term] id: CHEBI:67142 name: nucleobase analogue namespace: chebi_ontology def: "A molecule that can substitute for a normal nucleobase in nucleic acids." [] subset: 3_STAR synonym: "base analog" RELATED [ChEBI] synonym: "base analogs" RELATED [ChEBI] synonym: "base analogue" RELATED [ChEBI] synonym: "base analogues" RELATED [ChEBI] synonym: "nucleobase analog" RELATED [ChEBI] synonym: "nucleobase analogs" RELATED [ChEBI] synonym: "nucleobase analogues" RELATED [ChEBI] xref: Wikipedia:Base_analog is_a: CHEBI:33832 ! organic cyclic compound is_a: FBcv:0000548 ! base analog equivalent_to: FBcv:0000548 ! base analog [Term] id: CHEBI:68472 name: pyrimidine deoxyribonucleoside namespace: chebi_ontology def: "A deoxyribonucleoside containing a pyrimidine base." [] subset: 3_STAR synonym: "pyrimidine deoxyribonucleosides" RELATED [ChEBI] xref: MetaCyc:Pyrimidine-Deoxyribonucleosides is_a: CHEBI:23636 ! deoxyribonucleoside is_a: CHEBI:26440 ! pyrimidine nucleoside [Term] id: CHEBI:68494 name: apoptosis inhibitor namespace: chebi_ontology def: "Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms." [] subset: 3_STAR synonym: "apoptosis inhibitors" RELATED [ChEBI] synonym: "Type I cell-death inhibitor" RELATED [ChEBI] synonym: "Type I cell-death inhibitors" RELATED [ChEBI] synonym: "Type I programmed cell-death inhibitor" RELATED [ChEBI] synonym: "Type I programmed cell-death inhibitors" RELATED [ChEBI] is_a: CHEBI:35222 ! inhibitor is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:68495 name: apoptosis inducer namespace: chebi_ontology def: "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." [] subset: 3_STAR synonym: "apoptosis inducers" RELATED [ChEBI] synonym: "Type I cell-death inducer" RELATED [ChEBI] synonym: "Type I cell-death inducers" RELATED [ChEBI] synonym: "Type I programmed cell-death inducer" RELATED [ChEBI] synonym: "Type I programmed cell-death inducers" RELATED [ChEBI] is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:70727 name: topoisomerase inhibitor namespace: chebi_ontology def: "An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA)." [] subset: 3_STAR synonym: "topoisomerase inhibitors" RELATED [ChEBI] xref: Wikipedia:Topoisomerase is_a: CHEBI:76830 ! EC 5.99.1.* (miscellaneous isomerase) inhibitor [Term] id: CHEBI:71232 name: adenosine receptor antagonist namespace: chebi_ontology def: "An antagonist at any adenosine receptor." [] subset: 3_STAR synonym: "adenosine receptor antagonists" RELATED [ChEBI] xref: Wikipedia:Adenosine_receptor is_a: CHEBI:48706 ! antagonist [Term] id: CHEBI:71300 name: EC 2.* (transferase) inhibitor namespace: chebi_ontology def: "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" [] subset: 3_STAR synonym: "EC 2 inhibitor" RELATED [ChEBI] synonym: "EC 2 inhibitors" RELATED [ChEBI] synonym: "EC 2.* (transferase) inhibitors" RELATED [ChEBI] synonym: "EC 2.* inhibitor" RELATED [ChEBI] synonym: "EC 2.* inhibitors" RELATED [ChEBI] synonym: "transferase inhibitor" RELATED [ChEBI] synonym: "transferase inhibitors" RELATED [ChEBI] xref: Wikipedia:Transferase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:72544 name: flavonoids namespace: chebi_ontology def: "Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them." [] subset: 3_STAR synonym: "flavonoid" RELATED [ChEBI] xref: Wikipedia:Flavonoids is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:72695 name: organic molecule namespace: chebi_ontology def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." [] subset: 3_STAR synonym: "organic compound" RELATED [ChEBI] synonym: "organic compounds" RELATED [ChEBI] synonym: "organic molecules" RELATED [ChEBI] is_a: CHEBI:25367 ! molecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:72730 name: flavanone glycoside namespace: chebi_ontology def: "A member of the class of flavanones having one or more glycosyl residues attached at unspecified positions." [] subset: 3_STAR synonym: "flavanone glycosides" RELATED [ChEBI] is_a: CHEBI:24400 ! glycoside is_a: CHEBI:28863 ! flavanones [Term] id: CHEBI:73690 name: erythrose 4-phosphate/phosphoenolpyruvate family amino acid namespace: chebi_ontology def: "An L-alpha-amino acid which is biosynthesised from erythrose 4-phosphate and phosphoenolpyruvate (i.e. phenylalanine, tyrosine, and tryptophan). A closed class." [] subset: 3_STAR synonym: "erythrose 4-phosphate and phosphoenolpyruvate family amino acid" RELATED [ChEBI] synonym: "erythrose 4-phosphate and phosphoenolpyruvate family amino acids" RELATED [ChEBI] synonym: "erythrose 4-phosphate family amino acid" RELATED [ChEBI] synonym: "erythrose 4-phosphate family amino acids" RELATED [ChEBI] synonym: "erythrose 4-phosphate/phosphoenolpyruvate family amino acids" RELATED [ChEBI] synonym: "phosphoenolpyruvate family amino acid" RELATED [ChEBI] synonym: "phosphoenolpyruvate family amino acids" RELATED [ChEBI] is_a: CHEBI:15705 ! L-alpha-amino acid is_a: CHEBI:83813 ! proteinogenic amino acid [Term] id: CHEBI:73913 name: antifolate namespace: chebi_ontology def: "An antimetabolite that impairs the action of folic acids" [] subset: 3_STAR synonym: "antifolates" RELATED [ChEBI] synonym: "folic acid antagonist" RELATED [ChEBI] synonym: "folic acid antagonists" RELATED [ChEBI] xref: Wikipedia:Antifolate is_a: CHEBI:35221 ! antimetabolite [Term] id: CHEBI:74783 name: astringent namespace: chebi_ontology def: "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." [] subset: 3_STAR synonym: "adstringent" RELATED [ChEBI] synonym: "adstringents" RELATED [ChEBI] synonym: "astringents" RELATED [ChEBI] xref: Wikipedia:Astringent is_a: CHEBI:23888 ! drug [Term] id: CHEBI:75596 name: EC 5.* (isomerase) inhibitor namespace: chebi_ontology def: "An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*)." [] subset: 3_STAR synonym: "EC 5.* (isomerase) inhibitors" RELATED [ChEBI] synonym: "EC 5.* inhibitor" RELATED [ChEBI] synonym: "EC 5.* inhibitors" RELATED [ChEBI] synonym: "EC 5.*.*.* inhibitor" RELATED [ChEBI] synonym: "EC 5.*.*.* inhibitors" RELATED [ChEBI] synonym: "isomerase (EC 5.*) inhibitor" RELATED [ChEBI] synonym: "isomerase (EC 5.*) inhibitors" RELATED [ChEBI] synonym: "isomerase inhibitor" RELATED [ChEBI] synonym: "isomerase inhibitors" RELATED [ChEBI] is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:75600 name: EC 6.3.* (C-N bond-forming ligase) inhibitor namespace: chebi_ontology def: "A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*)." [] subset: 3_STAR synonym: "C--N bond-forming ligase inhibitor" RELATED [ChEBI] synonym: "C--N bond-forming ligase inhibitors" RELATED [ChEBI] synonym: "C-N bond-forming ligase (EC 6.3.*) inhibitor" RELATED [ChEBI] synonym: "C-N bond-forming ligase (EC 6.3.*) inhibitors" RELATED [ChEBI] synonym: "C-N bond-forming ligase inhibitor" RELATED [ChEBI] synonym: "C-N bond-forming ligase inhibitors" RELATED [ChEBI] synonym: "EC 6.3.* (C-N bond-forming ligase) inhibitorS" RELATED [ChEBI] synonym: "EC 6.3.* inhibitor" RELATED [ChEBI] synonym: "EC 6.3.* inhibitors" RELATED [ChEBI] synonym: "EC 6.3.*.* inhibitor" RELATED [ChEBI] synonym: "EC 6.3.*.* inhibitors" RELATED [ChEBI] is_a: CHEBI:75603 ! EC 6.* (ligase) inhibitor [Term] id: CHEBI:75603 name: EC 6.* (ligase) inhibitor namespace: chebi_ontology def: "Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." [] subset: 3_STAR synonym: "EC 6.* (ligase) inhibitors" RELATED [ChEBI] synonym: "EC 6.* inhibitor" RELATED [ChEBI] synonym: "EC 6.* inhibitors" RELATED [ChEBI] synonym: "EC 6.*.*.* inhibitor" RELATED [ChEBI] synonym: "EC 6.*.*.* inhibitors" RELATED [ChEBI] synonym: "ligase inhibitor" RELATED [ChEBI] synonym: "ligase inhibitors" RELATED [ChEBI] xref: Wikipedia:Ligase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:75763 name: eukaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." [] subset: 3_STAR synonym: "eukaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:75767 name: animal metabolite namespace: chebi_ontology alt_id: CHEBI:77721 alt_id: CHEBI:77743 def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." [] subset: 3_STAR synonym: "animal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:75768 name: mammalian metabolite namespace: chebi_ontology alt_id: CHEBI:77464 alt_id: CHEBI:77744 def: "Any animal metabolite produced during a metabolic reaction in mammals." [] subset: 3_STAR synonym: "mammalian metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:75769 name: B vitamin namespace: chebi_ontology def: "Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B1, B2, B3, B5, B6, B7, B9, and B12 (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such)." [] subset: 3_STAR synonym: "B vitamins" RELATED [ChEBI] synonym: "B-group vitamin" RELATED [ChEBI] synonym: "B-group vitamins" RELATED [ChEBI] synonym: "vitamin B" RELATED [ChEBI] xref: MetaCyc:B-vitamins xref: PMID:22743781 {source="Europe PMC"} xref: PMID:23093174 {source="Europe PMC"} xref: PMID:23238962 {source="Europe PMC"} xref: PMID:23449527 {source="Europe PMC"} xref: PMID:23462586 {source="Europe PMC"} xref: PMID:23690582 {source="Europe PMC"} xref: Wikipedia:B_vitamin is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_role CHEBI:27314 ! water-soluble vitamin (role) relationship: has_role CHEBI:50733 ! nutraceutical [Term] id: CHEBI:75771 name: mouse metabolite namespace: chebi_ontology def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." [] subset: 3_STAR synonym: "mouse metabolites" RELATED [ChEBI] synonym: "Mus musculus metabolite" RELATED [ChEBI] synonym: "Mus musculus metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:75772 name: Saccharomyces cerevisiae metabolite namespace: chebi_ontology alt_id: CHEBI:76949 alt_id: CHEBI:76951 def: "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." [] subset: 3_STAR synonym: "baker's yeast metabolite" RELATED [ChEBI] synonym: "baker's yeast metabolites" RELATED [ChEBI] synonym: "baker's yeast secondary metabolite" RELATED [ChEBI] synonym: "baker's yeast secondary metabolites" RELATED [ChEBI] synonym: "S. cerevisiae metabolite" RELATED [ChEBI] synonym: "S. cerevisiae metabolites" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolite" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae secondary metabolites" RELATED [ChEBI] is_a: CHEBI:76946 ! fungal metabolite [Term] id: CHEBI:75787 name: prokaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." [] subset: 3_STAR synonym: "prokaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76042 name: aromatic amino-acid zwitterion namespace: chebi_ontology def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid." [] subset: 3_STAR synonym: "an aromatic amino-acid" RELATED [UniProt] synonym: "aromatic amino-acid zwitterions" RELATED [ChEBI] xref: MetaCyc:Aromatic-Amino-Acids {source="SUBMITTER"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_tautomer_of CHEBI:33856 ! aromatic amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C([*])C([O-])=O" xsd:string [Term] id: CHEBI:76206 name: xenobiotic metabolite namespace: chebi_ontology def: "Any metabolite produced by metabolism of a xenobiotic compound." [] subset: 3_STAR synonym: "xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76414 name: propellant namespace: chebi_ontology def: "A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans." [] subset: 3_STAR synonym: "propellants" RELATED [ChEBI] xref: PMID:22519407 {source="Europe PMC"} xref: PMID:24001847 {source="Europe PMC"} is_a: CHEBI:33232 ! application [Term] id: CHEBI:76507 name: marine metabolite namespace: chebi_ontology alt_id: CHEBI:77078 def: "Any metabolite produced during a metabolic reaction in marine macro- and microorganisms." [] subset: 3_STAR synonym: "marine metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76551 name: N-nitrosoureas namespace: chebi_ontology def: "A nitroso compound that is any urea in which one of the nitrogens is substituted by a nitroso group" [] subset: 3_STAR is_a: CHEBI:35800 ! nitroso compound is_a: CHEBI:47857 ! ureas [Term] id: CHEBI:76668 name: EC 2.7.* (P-containing group transferase) inhibitor namespace: chebi_ontology def: "A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*)." [] subset: 3_STAR synonym: "EC 2.7.* (P-containing group transferase) inhibitors" RELATED [ChEBI] synonym: "EC 2.7.* (phosphorus-containing group transferase) inhibitor" RELATED [ChEBI] synonym: "EC 2.7.* (phosphorus-containing group transferase) inhibitors" RELATED [ChEBI] synonym: "EC 2.7.* inhibitor" RELATED [ChEBI] synonym: "EC 2.7.* inhibitors" RELATED [ChEBI] synonym: "phosphorus-containing group transferase (EC 2.7.*) inhibitor" RELATED [ChEBI] synonym: "phosphorus-containing group transferase (EC 2.7.*) inhibitors" RELATED [ChEBI] synonym: "phosphorus-containing group transferase inhibitor" RELATED [ChEBI] synonym: "phosphorus-containing group transferase inhibitors" RELATED [ChEBI] is_a: CHEBI:71300 ! EC 2.* (transferase) inhibitor [Term] id: CHEBI:76697 name: EC 5.99.* (other isomerases) inhibitor namespace: chebi_ontology def: "An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*)." [] subset: 3_STAR synonym: "EC 5.99.* (miscellaneous isomerases) inhibitor" RELATED [ChEBI] synonym: "EC 5.99.* (miscellaneous isomerases) inhibitors" RELATED [ChEBI] synonym: "EC 5.99.* (other isomerase) inhibitor" RELATED [ChEBI] synonym: "EC 5.99.* (other isomerase) inhibitors" RELATED [ChEBI] synonym: "EC 5.99.* (other isomerases) inhibitors" RELATED [ChEBI] synonym: "EC 5.99.* inhibitor" RELATED [ChEBI] synonym: "EC 5.99.* inhibitors" RELATED [ChEBI] is_a: CHEBI:75596 ! EC 5.* (isomerase) inhibitor [Term] id: CHEBI:76725 name: EC 1.* (oxidoreductase) inhibitor namespace: chebi_ontology def: "An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*)." [] subset: 3_STAR synonym: "EC 1.* (oxidoreductase) inhibitors" RELATED [ChEBI] synonym: "EC 1.* inhibitor" RELATED [ChEBI] synonym: "EC 1.* inhibitors" RELATED [ChEBI] synonym: "oxidoreductase (EC 1.*) inhibitor" RELATED [ChEBI] synonym: "oxidoreductase (EC 1.*) inhibitors" RELATED [ChEBI] synonym: "oxidoreductase inhibitor" RELATED [ChEBI] synonym: "oxidoreductase inhibitors" RELATED [ChEBI] xref: Wikipedia:Oxidoreductase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:76731 name: EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor namespace: chebi_ontology def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*)." [] subset: 3_STAR synonym: "EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors" RELATED [ChEBI] synonym: "EC 1.5.* inhibitor" RELATED [ChEBI] synonym: "EC 1.5.* inhibitors" RELATED [ChEBI] synonym: "inhibitor of oxidoreductase acting on CH-NH group of donor" RELATED [ChEBI] synonym: "inhibitor of oxidoreductase acting on CH-NH group of donors" RELATED [ChEBI] synonym: "inhibitors of oxidoreductase acting on CH-NH group of donor" RELATED [ChEBI] synonym: "inhibitors of oxidoreductase acting on CH-NH group of donors" RELATED [ChEBI] synonym: "oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor" RELATED [ChEBI] synonym: "oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor [Term] id: CHEBI:76735 name: EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor namespace: chebi_ontology def: "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors)." [] subset: 3_STAR synonym: "EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitors" RELATED [ChEBI] synonym: "EC 1.8.* inhibitor" RELATED [ChEBI] synonym: "EC 1.8.* inhibitors" RELATED [ChEBI] synonym: "oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitor" RELATED [ChEBI] synonym: "oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76725 ! EC 1.* (oxidoreductase) inhibitor [Term] id: CHEBI:76759 name: EC 3.* (hydrolase) inhibitor namespace: chebi_ontology def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." [] subset: 3_STAR synonym: "EC 3.* (hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.* inhibitor" RELATED [ChEBI] synonym: "EC 3.* inhibitors" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitor" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitors" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitor" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitors" RELATED [ChEBI] synonym: "hydrolase inhibitor" RELATED [ChEBI] synonym: "hydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Hydrolase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:76760 name: EC 3.1.* (ester hydrolase) inhibitor namespace: chebi_ontology def: "A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*)." [] subset: 3_STAR synonym: "EC 3.1.* (ester hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.1.* inhibitor" RELATED [ChEBI] synonym: "EC 3.1.* inhibitors" RELATED [ChEBI] synonym: "ester hydrolase (EC 3.1.*) inhibitor" RELATED [ChEBI] synonym: "ester hydrolase (EC 3.1.*) inhibitors" RELATED [ChEBI] synonym: "ester hydrolase inhibitor" RELATED [ChEBI] synonym: "ester hydrolase inhibitors" RELATED [ChEBI] is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor [Term] id: CHEBI:76764 name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor namespace: chebi_ontology def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." [] subset: 3_STAR synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* inhibitors" RELATED [ChEBI] is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor [Term] id: CHEBI:76775 name: EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor namespace: chebi_ontology def: "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*)." [] subset: 3_STAR synonym: "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.1.3.* inhibitor" RELATED [ChEBI] synonym: "EC 3.1.3.* inhibitors" RELATED [ChEBI] synonym: "inhibitor of phosphoric monoester hydrolase" RELATED [ChEBI] synonym: "inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)" RELATED [ChEBI] synonym: "inhibitors of phosphoric monoester hydrolase" RELATED [ChEBI] synonym: "inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)" RELATED [ChEBI] synonym: "phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor" RELATED [ChEBI] synonym: "phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors" RELATED [ChEBI] synonym: "phosphoric monoester hydrolase inhibitor" RELATED [ChEBI] synonym: "phosphoric monoester hydrolase inhibitors" RELATED [ChEBI] is_a: CHEBI:76760 ! EC 3.1.* (ester hydrolase) inhibitor [Term] id: CHEBI:76807 name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor namespace: chebi_ontology def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." [] subset: 3_STAR synonym: "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitors" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor [Term] id: CHEBI:76812 name: EC 2.7.11.* (protein-serine/threonine kinase) inhibitor namespace: chebi_ontology def: "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*)." [] subset: 3_STAR synonym: "EC 2.7.11.* (protein-serine/threonine kinase) inhibitors" RELATED [ChEBI] synonym: "EC 2.7.11.* inhibitor" RELATED [ChEBI] synonym: "EC 2.7.11.* inhibitors" RELATED [ChEBI] synonym: "protein-serine/threonine kinase (EC 2.7.11.*) inhibitor" RELATED [ChEBI] synonym: "protein-serine/threonine kinase (EC 2.7.11.*) inhibitors" RELATED [ChEBI] synonym: "protein-serine/threonine kinase inhibitor" RELATED [ChEBI] synonym: "protein-serine/threonine kinase inhibitors" RELATED [ChEBI] is_a: CHEBI:37699 ! protein kinase inhibitor [Term] id: CHEBI:76815 name: EC 2.7.7.* (nucleotidyltransferase) inhibitor namespace: chebi_ontology def: "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*)." [] subset: 3_STAR synonym: "EC 2.7.7.* (nucleotidyltransferase) inhibitors" RELATED [ChEBI] synonym: "inhibitor of nucleotidyltransferases" RELATED [ChEBI] synonym: "inhibitor of nucleotidyltransferases (EC 2.7.7.*)" RELATED [ChEBI] synonym: "inhibitors of nucleotidyltransferases" RELATED [ChEBI] synonym: "inhibitors of nucleotidyltransferases (EC 2.7.7.*)" RELATED [ChEBI] synonym: "nucleotidyltransferase (EC 2.7.7.*) inhibitor" RELATED [ChEBI] synonym: "nucleotidyltransferase (EC 2.7.7.*) inhibitors" RELATED [ChEBI] synonym: "nucleotidyltransferase inhibitor" RELATED [ChEBI] synonym: "nucleotidyltransferase inhibitors" RELATED [ChEBI] is_a: CHEBI:76668 ! EC 2.7.* (P-containing group transferase) inhibitor [Term] id: CHEBI:76823 name: EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor namespace: chebi_ontology def: "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*)." [] subset: 3_STAR synonym: "acid-ammonia (or amine) ligase inhibitor" RELATED [ChEBI] synonym: "acid-ammonia (or amine) ligase inhibitors" RELATED [ChEBI] synonym: "EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors" RELATED [ChEBI] synonym: "EC 6.3.1.* inhibitor" RELATED [ChEBI] synonym: "EC 6.3.1.* inhibitors" RELATED [ChEBI] is_a: CHEBI:75600 ! EC 6.3.* (C-N bond-forming ligase) inhibitor [Term] id: CHEBI:76830 name: EC 5.99.1.* (miscellaneous isomerase) inhibitor namespace: chebi_ontology def: "An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class." [] subset: 3_STAR synonym: "EC 5.99.1.* (miscellaneous isomerase) inhibitors" RELATED [ChEBI] synonym: "EC 5.99.1.* inhibitor" RELATED [ChEBI] synonym: "EC 5.99.1.* inhibitors" RELATED [ChEBI] is_a: CHEBI:76697 ! EC 5.99.* (other isomerases) inhibitor [Term] id: CHEBI:76863 name: EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor namespace: chebi_ontology def: "An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*)." [] subset: 3_STAR synonym: "EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors" RELATED [ChEBI] synonym: "EC 1.5.1.* inhibitor" RELATED [ChEBI] synonym: "EC 1.5.1.* inhibitors" RELATED [ChEBI] synonym: "oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor" RELATED [ChEBI] synonym: "oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76731 ! EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor [Term] id: CHEBI:76869 name: EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor namespace: chebi_ontology def: "An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*)." [] subset: 3_STAR synonym: "EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitors" RELATED [ChEBI] synonym: "EC 1.8.1.* inhibitor" RELATED [ChEBI] synonym: "EC 1.8.1.* inhibitors" RELATED [ChEBI] synonym: "oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitor" RELATED [ChEBI] synonym: "oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76735 ! EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor [Term] id: CHEBI:76924 name: plant metabolite namespace: chebi_ontology alt_id: CHEBI:75766 alt_id: CHEBI:76925 def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." [] subset: 3_STAR synonym: "plant metabolites" RELATED [ChEBI] synonym: "plant secondary metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76946 name: fungal metabolite namespace: chebi_ontology alt_id: CHEBI:75765 alt_id: CHEBI:76947 def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." [] subset: 3_STAR synonym: "fungal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76967 name: human xenobiotic metabolite namespace: chebi_ontology def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." [] subset: 3_STAR synonym: "human xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:76206 ! xenobiotic metabolite is_a: CHEBI:77746 ! human metabolite [Term] id: CHEBI:76969 name: bacterial metabolite namespace: chebi_ontology alt_id: CHEBI:75760 alt_id: CHEBI:76970 def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." [] subset: 3_STAR is_a: CHEBI:75787 ! prokaryotic metabolite [Term] id: CHEBI:76971 name: Escherichia coli metabolite namespace: chebi_ontology def: "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." [] subset: 3_STAR synonym: "E.coli metabolite" RELATED [ChEBI] synonym: "E.coli metabolites" RELATED [ChEBI] synonym: "Escherichia coli metabolites" RELATED [ChEBI] is_a: CHEBI:76969 ! bacterial metabolite [Term] id: CHEBI:77402 name: EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor namespace: chebi_ontology def: "An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12)." [] subset: 3_STAR synonym: "EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors" RELATED [ChEBI] synonym: "EC 1.8.1.12 inhibitor" RELATED [ChEBI] synonym: "EC 1.8.1.12 inhibitors" RELATED [ChEBI] synonym: "N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitor" RELATED [ChEBI] synonym: "N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitors" RELATED [ChEBI] synonym: "NADPH2:trypanothione oxidoreductase inhibitor" RELATED [ChEBI] synonym: "NADPH2:trypanothione oxidoreductase inhibitors" RELATED [ChEBI] synonym: "NADPH:trypanothione oxidoreductase inhibitor" RELATED [ChEBI] synonym: "NADPH:trypanothione oxidoreductase inhibitors" RELATED [ChEBI] synonym: "trypanothione reductase inhibitor" RELATED [ChEBI] synonym: "trypanothione reductase inhibitors" RELATED [ChEBI] synonym: "trypanothione-disulfide reductase (EC 1.8.1.12) inhibitor" RELATED [ChEBI] synonym: "trypanothione-disulfide reductase (EC 1.8.1.12) inhibitors" RELATED [ChEBI] synonym: "trypanothione:NADP(+) oxidoreductase inhibitor" RELATED [ChEBI] synonym: "trypanothione:NADP(+) oxidoreductase inhibitors" RELATED [ChEBI] xref: Wikipedia:Trypanothione-disulfide_reductase is_a: CHEBI:76869 ! EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor [Term] id: CHEBI:77746 name: human metabolite namespace: chebi_ontology alt_id: CHEBI:75770 alt_id: CHEBI:77123 def: "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." [] subset: 3_STAR synonym: "H. sapiens metabolite" RELATED [ChEBI] synonym: "H. sapiens metabolites" RELATED [ChEBI] synonym: "Homo sapiens metabolite" RELATED [ChEBI] synonym: "Homo sapiens metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:77941 name: EC 3.5.1.4 (amidase) inhibitor namespace: chebi_ontology def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." [] subset: 3_STAR synonym: "acylamidase inhibitor" RELATED [ChEBI] synonym: "acylamidase inhibitors" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitor" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitors" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitor" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitors" RELATED [ChEBI] synonym: "amidase inhibitor" RELATED [ChEBI] synonym: "amidase inhibitors" RELATED [ChEBI] synonym: "amidohydrolase inhibitor" RELATED [ChEBI] synonym: "amidohydrolase inhibitors" RELATED [ChEBI] synonym: "deaminase inhibitor" RELATED [ChEBI] synonym: "deaminase inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 (amidase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitors" RELATED [ChEBI] synonym: "fatty acylamidase inhibitor" RELATED [ChEBI] synonym: "fatty acylamidase inhibitors" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitor" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Amidase is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor [Term] id: CHEBI:78017 name: food propellant namespace: chebi_ontology def: "A propellant that is used to expel foods from an aerosol container." [] subset: 3_STAR synonym: "food propellants" RELATED [ChEBI] is_a: CHEBI:64047 ! food additive is_a: CHEBI:76414 ! propellant [Term] id: CHEBI:78295 name: food component namespace: chebi_ontology def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." [] subset: 3_STAR synonym: "dietary component" RELATED [ChEBI] synonym: "dietary components" RELATED [ChEBI] synonym: "food components" RELATED [ChEBI] is_a: CHEBI:52211 ! physiological role [Term] id: CHEBI:78298 name: environmental contaminant namespace: chebi_ontology def: "Any minor or unwanted substance introduced into the environment that can have undesired effects." [] subset: 3_STAR synonym: "environmental contaminants" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:78433 name: refrigerant namespace: chebi_ontology def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." [] subset: 3_STAR synonym: "refrigerants" RELATED [ChEBI] xref: Wikipedia:Refrigerant is_a: CHEBI:33232 ! application [Term] id: CHEBI:78592 name: vesicant namespace: chebi_ontology def: "Any compound that causes severe skin, eye and mucosal pain and irritation." [] subset: 3_STAR synonym: "blister agent" RELATED [ChEBI] synonym: "blister agents" RELATED [ChEBI] synonym: "vesicants" RELATED [ChEBI] xref: PMID:16168310 {source="Europe PMC"} xref: Wikipedia:Blister_agent is_a: CHEBI:52208 ! biophysical role [Term] id: CHEBI:78608 name: alpha-amino acid zwitterion namespace: chebi_ontology alt_id: CHEBI:83409 def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." [] subset: 3_STAR synonym: "an alpha-amino acid" RELATED [UniProt] xref: MetaCyc:Alpha-Amino-Acids {source="SUBMITTER"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_tautomer_of CHEBI:33704 ! alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C([*])C([O-])=O" xsd:string [Term] id: CHEBI:78616 name: carbohydrates and carbohydrate derivatives namespace: chebi_ontology def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." [] subset: 3_STAR synonym: "carbohydrates and derivatives" RELATED [ChEBI] synonym: "carbohydrates and their derivatives" RELATED [ChEBI] is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:78675 name: fundamental metabolite namespace: chebi_ontology def: "Any metabolite produced by all living cells." [] subset: 3_STAR synonym: "essential metabolite" RELATED [ChEBI] synonym: "essential metabolites" RELATED [ChEBI] synonym: "fundamental metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:79387 name: trivalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of three." [] subset: 3_STAR synonym: "trivalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79388 name: divalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of two." [] subset: 3_STAR synonym: "divalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79389 name: monovalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of one." [] subset: 3_STAR synonym: "monovalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:83039 name: crustacean metabolite namespace: chebi_ontology def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." [] subset: 3_STAR synonym: "crustacean metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:83056 name: Daphnia magna metabolite namespace: chebi_ontology def: "A Daphnia metabolite produced by the species Daphnia magna." [] subset: 3_STAR synonym: "Daphnia magna metabolites" RELATED [ChEBI] is_a: CHEBI:83057 ! Daphnia metabolite [Term] id: CHEBI:83057 name: Daphnia metabolite namespace: chebi_ontology def: "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" [] subset: 3_STAR synonym: "Daphnia metabolites" RELATED [ChEBI] xref: Wikipedia:Daphnia is_a: CHEBI:83039 ! crustacean metabolite [Term] id: CHEBI:83347 name: organosulfonic ester namespace: chebi_ontology def: "An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid." [] subset: 3_STAR synonym: "organosulfonate ester" RELATED [ChEBI] synonym: "organosulfonate esters" RELATED [ChEBI] synonym: "organosulfonic esters" RELATED [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative is_a: CHEBI:35701 ! ester relationship: has_functional_parent CHEBI:33551 ! organosulfonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O3SR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "80.06300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "79.95681" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]S(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:83414 name: alkyl sulfate(1-) namespace: chebi_ontology def: "An organosulfate oxoanion obtained by deprotonation of the sulfo group of any alkyl sulfate; major species at pH 7.3." [] subset: 3_STAR synonym: "alkyl sulfate anion" RELATED [ChEBI] synonym: "an alkyl sulfate" RELATED [UniProt] xref: MetaCyc:Organo-Sulfates {source="SUBMITTER"} is_a: CHEBI:58958 ! organosulfate oxoanion relationship: is_conjugate_base_of CHEBI:29281 ! alkyl sulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.064" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:83811 name: proteinogenic amino acid derivative namespace: chebi_ontology def: "Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom." [] subset: 3_STAR synonym: "canonical amino acid derivative" RELATED [ChEBI] synonym: "canonical amino acid derivatives" RELATED [ChEBI] synonym: "canonical amino-acid derivative" RELATED [ChEBI] synonym: "canonical amino-acid derivatives" RELATED [ChEBI] synonym: "proteinogenic amino acid derivatives" RELATED [ChEBI] synonym: "proteinogenic amino-acid derivative" RELATED [ChEBI] synonym: "proteinogenic amino-acid derivatives" RELATED [ChEBI] is_a: CHEBI:83821 ! amino acid derivative relationship: has_functional_parent CHEBI:83813 ! proteinogenic amino acid [Term] id: CHEBI:83812 name: non-proteinogenic amino acid derivative namespace: chebi_ontology def: "Any derivative of a non-proteinogenic amino acid resulting from reaction at an amino group or carboxy group, or from the replacement of any hydrogen by a heteroatom." [] subset: 3_STAR synonym: "non-canonical amino acid derivative" RELATED [ChEBI] synonym: "non-canonical amino-acid derivatives" RELATED [ChEBI] synonym: "non-proteinogenic amino-acid derivatives" RELATED [ChEBI] is_a: CHEBI:83821 ! amino acid derivative [Term] id: CHEBI:83813 name: proteinogenic amino acid namespace: chebi_ontology def: "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." [] subset: 3_STAR synonym: "canonical amino acid" RELATED [ChEBI] synonym: "canonical amino acids" RELATED [ChEBI] synonym: "proteinogenic amino acids" RELATED [ChEBI] xref: Wikipedia:Proteinogenic_amino_acid is_a: CHEBI:33575 ! carboxylic acid is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:83820 name: non-proteinogenic amino acid namespace: chebi_ontology def: "Any amino-acid that is not naturally encoded in the genetic code of any organism." [] subset: 3_STAR synonym: "non-canonical amino acid" RELATED [ChEBI] synonym: "non-canonical amino acids" RELATED [ChEBI] synonym: "non-canonical amino-acid" RELATED [ChEBI] synonym: "non-canonical amino-acids" RELATED [ChEBI] synonym: "non-coded amino acid" RELATED [ChEBI] synonym: "non-coded amino acids" RELATED [ChEBI] synonym: "non-coded amino-acid" RELATED [ChEBI] synonym: "non-coded amino-acids" RELATED [ChEBI] synonym: "non-proteinogenic amino acids" RELATED [ChEBI] synonym: "non-proteinogenic amino-acid" RELATED [ChEBI] synonym: "non-proteinogenic amino-acids" RELATED [ChEBI] xref: Wikipedia:Non-proteinogenic_amino_acids is_a: CHEBI:33709 ! amino acid [Term] id: CHEBI:83821 name: amino acid derivative namespace: chebi_ontology alt_id: CHEBI:25359 def: "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." [] subset: 3_STAR synonym: "amino acid derivatives" RELATED [ChEBI] synonym: "modified amino acids" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:83822 name: non-proteinogenic L-alpha-amino acid namespace: chebi_ontology def: "Any L-alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids." [] subset: 3_STAR synonym: "non-proteinogenic L-alpha-amino acids" RELATED [ChEBI] is_a: CHEBI:15705 ! L-alpha-amino acid is_a: CHEBI:83925 ! non-proteinogenic alpha-amino acid [Term] id: CHEBI:83925 name: non-proteinogenic alpha-amino acid namespace: chebi_ontology def: "Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids." [] subset: 3_STAR synonym: "non-proteinogenic alpha-amino acids" RELATED [ChEBI] synonym: "non-proteinogenic alpha-amino-acid" RELATED [ChEBI] synonym: "non-proteinogenic alpha-amino-acids" RELATED [ChEBI] is_a: CHEBI:33704 ! alpha-amino acid is_a: CHEBI:83820 ! non-proteinogenic amino acid [Term] id: CHEBI:83982 name: L-glutamic acid derivative namespace: chebi_ontology def: "A proteinogenic amino acid derivative resulting from reaction of L-glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen of L-glutamic acid by a heteroatom." [] subset: 3_STAR synonym: "L-glutamic acid derivatives" RELATED [ChEBI] is_a: CHEBI:24315 ! glutamic acid derivative is_a: CHEBI:83811 ! proteinogenic amino acid derivative relationship: has_functional_parent CHEBI:16015 ! L-glutamic acid [Term] id: CHEBI:84087 name: human urinary metabolite namespace: chebi_ontology def: "Any metabolite (endogenous or exogenous) found in human urine samples." [] subset: 3_STAR synonym: "human urinary metabolites" RELATED [ChEBI] is_a: CHEBI:77746 ! human metabolite [Term] id: CHEBI:84143 name: D-phenylalanine derivative namespace: chebi_ontology def: "A non-proteinogenic amino acid derivative resulting from reaction of D-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of D-phenylalanine by a heteroatom." [] subset: 3_STAR synonym: "D-phenylalanine derivatives" RELATED [ChEBI] is_a: CHEBI:25985 ! phenylalanine derivative is_a: CHEBI:83812 ! non-proteinogenic amino acid derivative relationship: has_functional_parent CHEBI:16998 ! D-phenylalanine [Term] id: CHEBI:84144 name: L-phenylalanine derivative namespace: chebi_ontology def: "A proteinogenic amino acid derivative resulting from reaction of L-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-phenylalanine by a heteroatom." [] subset: 3_STAR synonym: "L-phenylalanine derivatives" RELATED [ChEBI] is_a: CHEBI:25985 ! phenylalanine derivative is_a: CHEBI:83811 ! proteinogenic amino acid derivative relationship: has_functional_parent CHEBI:17295 ! L-phenylalanine [Term] id: CHEBI:84735 name: algal metabolite namespace: chebi_ontology def: "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." [] subset: 3_STAR synonym: "algal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:85046 name: skin lightening agent namespace: chebi_ontology def: "Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin." [] subset: 3_STAR synonym: "melanogenesis inhibitor" RELATED [ChEBI] synonym: "melanogenesis inhibitors" RELATED [ChEBI] synonym: "skin bleaching agent" RELATED [ChEBI] synonym: "skin bleaching agents" RELATED [ChEBI] synonym: "skin depigmenting agent" RELATED [ChEBI] synonym: "skin depigmenting agents" RELATED [ChEBI] synonym: "skin lightening agents" RELATED [ChEBI] synonym: "skin whitening agent" RELATED [ChEBI] synonym: "skin whitening agents" RELATED [ChEBI] xref: PMID:21265866 {source="Europe PMC"} xref: PMID:22132817 {source="Europe PMC"} xref: PMID:22314516 {source="Europe PMC"} xref: PMID:23891889 {source="Europe PMC"} xref: PMID:23974587 {source="Europe PMC"} xref: PMID:25535470 {source="Europe PMC"} xref: PMID:25574195 {source="Europe PMC"} xref: PMID:25643794 {source="Europe PMC"} xref: Wikipedia:Skin_whitening is_a: CHEBI:64857 ! cosmetic [Term] id: CHEBI:85234 name: human blood serum metabolite namespace: chebi_ontology def: "Any metabolite (endogenous or exogenous) found in human blood serum samples." [] subset: 3_STAR synonym: "human blood serum metabolites" RELATED [ChEBI] is_a: CHEBI:77746 ! human metabolite [Term] id: CHEBI:8711 name: quinacrine namespace: chebi_ontology def: "A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9." [] subset: 3_STAR synonym: "2-methoxy-6-chloro-9-diethylaminopentylaminoacridine" RELATED [ChemIDplus] synonym: "3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine" RELATED [ChemIDplus] synonym: "4-N-(6-chloro-2-methoxyacridin-9-yl)-1-N,1-N-diethylpentane-1,4-diamine" EXACT IUPAC_NAME [IUPAC] synonym: "6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine" RELATED [ChemIDplus] synonym: "Mepacrine" RELATED [KEGG_COMPOUND] synonym: "mepacrine" RELATED [ChemIDplus] synonym: "N(4)-(6-chloro-2-methoxy-9-acridinyl)-N(1),N(1)-diethyl-1,4-pentanediamine" RELATED [ChemIDplus] synonym: "Quinacrine" EXACT [KEGG_COMPOUND] xref: Beilstein:497807 {source="Beilstein"} xref: Beilstein:95500 {source="Beilstein"} xref: CAS:83-89-6 {source="ChemIDplus"} xref: CAS:83-89-6 {source="KEGG COMPOUND"} xref: Drug_Central:2338 {source="DrugCentral"} xref: DrugBank:DB01103 xref: HMDB:HMDB0015235 xref: KEGG:C07339 xref: KEGG:D08179 xref: LINCS:LSM-1577 xref: MetaCyc:ATABRINE xref: PMID:11339632 {source="Europe PMC"} xref: PMID:11908878 {source="Europe PMC"} xref: PMID:19747949 {source="Europe PMC"} xref: Reaxys:95500 {source="Reaxys"} xref: Wikipedia:Quinacrine is_a: CHEBI:22213 ! acridines is_a: CHEBI:35618 ! aromatic ether is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:50996 ! tertiary amino compound is_a: FBcv:0000551 ! enzyme inhibitor relationship: has_parent_hydride CHEBI:36420 ! acridine relationship: has_role CHEBI:38068 ! antimalarial relationship: has_role CHEBI:77402 ! EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C23H30ClN3O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C23H30ClN3O/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "GPKJTRJOBQGKQK-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "399.95700" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "399.20774" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc2ccc(OC)cc12" xsd:string [Term] id: CHEBI:88184 name: metal allergen namespace: chebi_ontology def: "Any metal which causes the onset of an allergic reaction." [] subset: 3_STAR synonym: "allergenic metal" RELATED [ChEBI] synonym: "allergenic metals" RELATED [ChEBI] synonym: "metal allergens" RELATED [ChEBI] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:33521 ! metal atom relationship: has_role CHEBI:50904 ! allergen [Term] id: CHEBI:88188 name: drug allergen namespace: chebi_ontology def: "Any drug which causes the onset of an allergic reaction." [] subset: 3_STAR synonym: "allergenic drug" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:50904 ! allergen [Term] id: CHEBI:90710 name: receptor modulator namespace: chebi_ontology def: "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." [] subset: 3_STAR synonym: "receptor modulators" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: FBcv:0000000 name: FlyBase CV def: "FlyBase miscellaneous controlled vocabulary term." [] [Term] id: FBcv:0000001 name: obsolete death certificate namespace: pub_type comment: This term was obsoleted because it was only ever used to annotate one publication: A copy of Calvin Bridges death certificate. This can still be found in the Drosophila offprint collection (FBrf0186653). is_obsolete: true [Term] id: FBcv:0000002 name: abnormal thermotaxis namespace: phenotypic_class def: "Phenotype that is any abnormality in thermotaxis (GO:0043052). 'thermotaxis' is defined as: 'The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.'" [FBC:DOS, GOC:cab1, WB_REF:cgc467] synonym: "thermotaxis behavior defective" EXACT [] synonym: "thermotaxis behaviour defective" EXACT [] synonym: "thermotaxis defective" EXACT [] is_a: FBcv:0000683 ! abnormal temperature response [Term] id: FBcv:0000003 name: obsolete In transgenic Drosophila (intraspecific) namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 xref: abbrev:1 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000004 name: obsolete Whole-organism transient assay (intraspecific) namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 xref: abbrev:2 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000005 name: qualifier def: "Term used to qualify a descriptor." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000000 ! FlyBase CV [Term] id: FBcv:0000006 name: male semi-fertile namespace: phenotypic_class def: "A phenotype that is a reduction in the ability of males to produce fertilized eggs as a result of mating, but only to > 50% of wild-type." [FBC:AO, FBC:CP, FBC:DOS] is_a: FBcv:0000375 ! semi-fertile is_a: FBcv:0000376 ! male fertile [Term] id: FBcv:0000007 name: female semi-fertile namespace: phenotypic_class def: "A phenotype that is a reduction in the ability of females to produce fertilized eggs as a result of mating, but only to > 50% of wild-type." [FBC:AO, FBC:CP, FBC:DOS] is_a: FBcv:0000375 ! semi-fertile is_a: FBcv:0000377 ! female fertile [Term] id: FBcv:0000008 name: modifier of variegation namespace: phenotypic_class def: "Genotype g1 is a modifier of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is significantly different from that caused by g2 alone." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "variegation" RELATED [FBC:DOS] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000009 name: obsolete temporal stage qualifier namespace: temporal_qualifier comment: This term has been obsoleted because all of its children terms have been obsoleted [FBC:MMC]. mc161027 xref: PATO:0000083 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000010 name: obsolete monophasic comment: This term has been obsoleted because there are new terms to replace it [FBC:MMC]. mc160113 xref: PATO:0001773 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000011 name: obsolete relative temporal qualifier namespace: temporal_qualifier comment: This term has been obsoleted because all of its children terms have been obsoleted [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000012 name: obsolete absolute temporal qualifier comment: This term has been obsoleted because both of its children terms have been obsoleted [FBC:MMC]. mc160113 xref: PATO:0000165 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000013 name: descriptor def: "Term that describes an allele, balancer, group or publication." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000000 ! FlyBase CV [Term] id: FBcv:0000014 name: structural qualifier namespace: structural_qualifier def: "Qualifier used to describe changes in number or location of an anatomical structure compared to wild type." [FBC:CP, FBC:MMC] subset: do_not_annotate is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000015 name: obsolete postage stamp namespace: pub_type comment: This term was obsoleted because it was little used. is_obsolete: true [Term] id: FBcv:0000016 name: obsolete Baylor TE recombination mapping kit stock comment: Consider - FBsv:0000605. is_obsolete: true [Term] id: FBcv:0000017 name: obsolete penetrance qualifier def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000018 name: obsolete penetrance complete def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is complete when all the individuals of a given genotype exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000019 name: obsolete penetrance incomplete def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only some the individuals of a given genotype exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000020 name: obsolete penetrance percent def: "Penetrance is the fraction of individuals of a given genotype who exhibit the phenotype associated with that genotype. Penetrance is incomplete when only a percentage of the individuals of a given genotype exhibit the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] comment: This term should be modified by a % value. This is not currently possible in FlyBase curation. is_obsolete: true [Term] id: FBcv:0000021 name: obsolete expressivity qualifier def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000022 name: obsolete expressivity complete def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is complete when an individual of a given genotype expresses the full phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000023 name: obsolete expressivity incomplete def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. Expressivity is incomplete when an individual of a given genotype expresses only partially the phenotype associated with that genotype." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000024 name: obsolete expressivity high def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. 'High expressivity' conveys that while expressivity is not complete, the phenotype expressed is approaching that of complete expressivity." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000025 name: obsolete expressivity low def: "Expressivity measures the extent to which a given genotype is expressed at the phenotypic level. 'Low expressivity' conveys that phenotype expressed is a much reduced version compared to complete expressivity." [ISBN:978-0-7167-3520-5] is_obsolete: true [Term] id: FBcv:0000026 name: obsolete recessive visible allele recombination mapping stock is_obsolete: true [Term] id: FBcv:0000027 name: obsolete dominant visible allele recombination mapping stock is_obsolete: true [Term] id: FBcv:0000028 name: obsolete SNP recombination mapping stock comment: Consider - FBsv:0001018. is_obsolete: true [Term] id: FBcv:0000029 name: obsolete transposable element mutagenesis stock is_obsolete: true [Term] id: FBcv:0000030 name: obsolete compartment namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000031 name: obsolete anterior compartment namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000032 name: obsolete compartment boundary namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000033 name: obsolete anterior/posterior compartment boundary namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000034 name: obsolete dorsal/ventral compartment boundary namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000035 name: obsolete dorsal compartment namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000036 name: obsolete posterior compartment namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000037 name: obsolete ventral compartment namespace: spatial_qualifier comment: This term was obsoleted because a term from the anatom ontology (FBbt) should be used instead. If possible, please use 'developmental compartment' (FBbt:00007110) or one of its subclasses [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000038 name: relative spatial qualifier namespace: spatial_qualifier def: "Qualifier that describes the spatial characteristics of a phenotype or expression pattern relative to the position of another entity." [FBC:CP] subset: do_not_annotate xref: PATO:0001631 is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000039 name: anterior to namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the front of an organism relative to another entity." [PATO:0001632] xref: PATO:0001632 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000040 name: distal to namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being located further from a more centrally located entity." [PATO:0001234] xref: PATO:0001234 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000041 name: dorsal to namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the back or upper surface of an organism relative to another entity." [PATO:0001233] xref: PATO:0001233 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000042 name: obsolete deficiency kit stock synonym: "deletion kit stock" RELATED [] is_obsolete: true [Term] id: FBcv:0000043 name: obsolete transposase source for transposable element mutagenesis comment: Consider - FBsv:0001020. is_obsolete: true [Term] id: FBcv:0000044 name: obsolete ammunition source for transposable element mutagenesis comment: Consider - FBsv:0001022. is_obsolete: true [Term] id: FBcv:0000045 name: posterior to namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the rear of an organism relative to another entity." [PATO:0001633] xref: PATO:0001633 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000046 name: precursor namespace: temporal_qualifier is_a: FBcv:0000176 ! temporal qualifier [Term] id: FBcv:0000047 name: proximal to namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being located more centrally than another entity." [PATO:0001195] xref: PATO:0001195 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000048 name: surrounding namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being extended on all sides of another entity simultaneously." [PATO:0001772] xref: PATO:0001772 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000049 name: ventral to namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the belly or lower surface of an organism relative to another entity." [FBC:CP] xref: PATO:0001196 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000050 name: vicinity of namespace: spatial_qualifier def: "A spatial quality inhering in a bearer by virtue of the bearer's being located near in space in relation to another entity." [PATO:0002259] synonym: "adjacent to" NARROW [PATO:0002259] xref: PATO:0002259 is_a: FBcv:0000038 ! relative spatial qualifier [Term] id: FBcv:0000051 name: segment boundary namespace: spatial_qualifier def: "Present in the area that separates segments." [FBC:MMC] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000052 name: spatial qualifier namespace: spatial_qualifier def: "Qualifier that describes the spatial characteristics of a phenotype or expression pattern." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000053 name: anterior namespace: spatial_qualifier def: "Restricted to anterior region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000054 name: apical namespace: spatial_qualifier def: "Restricted to apical region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000055 name: basal namespace: spatial_qualifier def: "Restricted to basal region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000056 name: central namespace: spatial_qualifier def: "Restricted to central region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000057 name: obsolete contralateral namespace: spatial_qualifier comment: This term has been obsoleted because there is no way to combine it with an anatomy term to produce a meaningful statement [FBC:MMC]. mc160113. is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000058 name: distal namespace: spatial_qualifier def: "Restricted to distal region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000059 name: dorsal namespace: spatial_qualifier def: "Restricted to dorsal region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000060 name: dorso-lateral namespace: spatial_qualifier def: "Restricted to dorso-lateral region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000061 name: ectopic namespace: structural_qualifier def: "Anatomical structure is present in a location in which it would not be present in wild-type." [FBC:CP] comment: An extra copy of an anatomical structure that is present in the same location as in wild-type should use 'increased number', rather than 'ectopic'. xref: PATO:0000628 is_a: FBcv:0000014 ! structural qualifier [Term] id: FBcv:0000062 name: obsolete ipsilateral namespace: spatial_qualifier comment: This term has been obsoleted because there is no way to combine it with an anatomy term to produce a meaningful statement [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000052 [Term] id: FBcv:0000063 name: lateral namespace: spatial_qualifier def: "Restricted to lateral region(s) of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000064 name: medial namespace: spatial_qualifier def: "Restricted to medial region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000065 name: posterior namespace: spatial_qualifier def: "Restricted to posterior region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000066 name: proximal namespace: spatial_qualifier def: "Restricted to proximal region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000067 name: restricted namespace: spatial_qualifier def: "Restricted to unknown part(s) of a specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000068 name: increased number namespace: structural_qualifier def: "Present in the correct location but in larger numbers than in wild-type." [FBC:DOS] synonym: "supernumerary" EXACT [] is_a: FBcv:0000014 ! structural qualifier [Term] id: FBcv:0000069 name: ubiquitous namespace: spatial_qualifier def: "Expressed everywhere at some specified stage." [FBC:DOS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000070 name: ventral namespace: spatial_qualifier def: "Restricted to ventral region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000071 name: ventro-lateral namespace: spatial_qualifier def: "Restricted to ventro-lateral region of some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000072 name: obsolete gene expression qualifier is_obsolete: true [Term] id: FBcv:0000073 name: obsolete embryonic expression pattern is_obsolete: true [Term] id: FBcv:0000074 name: egg length namespace: spatial_qualifier def: "Position in the egg or pre-gastrula embryo expressed as a percentage of egg length, where 0% corresponds to the posterior tip and 100% to the anterior tip." [FBC:DOS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000075 name: 0% egg length namespace: spatial_qualifier def: "At the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000076 name: 0-10% egg length namespace: spatial_qualifier def: "0-10% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000077 name: 0-100% egg length namespace: spatial_qualifier def: "The full length of the pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000078 name: 0-20% egg length namespace: spatial_qualifier def: "0-20% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000079 name: 0-30% egg length namespace: spatial_qualifier def: "0-30% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000080 name: 0-40% egg length namespace: spatial_qualifier def: "0-40% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000081 name: 0-50% egg length namespace: spatial_qualifier def: "0-50% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000082 name: 0-60% egg length namespace: spatial_qualifier def: "0-60% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000083 name: 0-70% egg length namespace: spatial_qualifier def: "0-70% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000084 name: 0-80% egg length namespace: spatial_qualifier def: "0-80% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000085 name: 0-90% egg length namespace: spatial_qualifier def: "0-90% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000086 name: 10% egg length namespace: spatial_qualifier def: "10% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000087 name: 10-100% egg length namespace: spatial_qualifier def: "10-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000088 name: 10-20% egg length namespace: spatial_qualifier def: "10-20% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000089 name: 10-30% egg length namespace: spatial_qualifier def: "10-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000090 name: 10-40% egg length namespace: spatial_qualifier def: "10-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000091 name: 10-50% egg length namespace: spatial_qualifier def: "10-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000092 name: 10-60% egg length namespace: spatial_qualifier def: "10-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000093 name: 10-70% egg length namespace: spatial_qualifier def: "10-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000094 name: 10-80% egg length namespace: spatial_qualifier def: "10-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000095 name: 10-90% egg length namespace: spatial_qualifier def: "10-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000096 name: 100% egg length namespace: spatial_qualifier def: "At the anterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000097 name: 20% egg length namespace: spatial_qualifier def: "20% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000098 name: 20-100% egg length namespace: spatial_qualifier def: "20-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000099 name: 20-30% egg length namespace: spatial_qualifier def: "20-30% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000100 name: 20-40% egg length namespace: spatial_qualifier def: "20-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000101 name: 20-50% egg length namespace: spatial_qualifier def: "20-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000102 name: 20-60% egg length namespace: spatial_qualifier def: "20-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000103 name: 20-70% egg length namespace: spatial_qualifier def: "20-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000104 name: 20-80% egg length namespace: spatial_qualifier def: "20-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000105 name: 20-90% egg length namespace: spatial_qualifier def: "20-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000106 name: 30% egg length namespace: spatial_qualifier def: "30% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000107 name: 30-100% egg length namespace: spatial_qualifier def: "30-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000108 name: 30-40% egg length namespace: spatial_qualifier def: "30-40% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000109 name: 30-50% egg length namespace: spatial_qualifier def: "30-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000110 name: 30-60% egg length namespace: spatial_qualifier def: "30-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000111 name: 30-70% egg length namespace: spatial_qualifier def: "30-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000112 name: 30-80% egg length namespace: spatial_qualifier def: "30-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000113 name: 30-90% egg length namespace: spatial_qualifier def: "30-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000114 name: 40% egg length namespace: spatial_qualifier def: "40% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000115 name: 40-100% egg length namespace: spatial_qualifier def: "40-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000116 name: 40-50% egg length namespace: spatial_qualifier def: "40-50% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000117 name: 40-60% egg length namespace: spatial_qualifier def: "40-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000118 name: 40-70% egg length namespace: spatial_qualifier def: "40-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000119 name: 40-80% egg length namespace: spatial_qualifier def: "40-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000120 name: 40-90% egg length namespace: spatial_qualifier def: "40-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000121 name: 50% egg length namespace: spatial_qualifier def: "50% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000122 name: 50-100% egg length namespace: spatial_qualifier def: "50-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000123 name: 50-60% egg length namespace: spatial_qualifier def: "50-60% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000124 name: 50-70% egg length namespace: spatial_qualifier def: "50-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000125 name: 50-80% egg length namespace: spatial_qualifier def: "50-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000126 name: 50-90% egg length namespace: spatial_qualifier def: "50-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000127 name: 60% egg length namespace: spatial_qualifier def: "60% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000128 name: 60-100% egg length namespace: spatial_qualifier def: "60-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000129 name: 60-80% egg length namespace: spatial_qualifier def: "60-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000130 name: 60-90% egg length namespace: spatial_qualifier def: "60-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000131 name: 70% egg length namespace: spatial_qualifier def: "70% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000132 name: 70-100% egg length namespace: spatial_qualifier def: "70-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000133 name: 70-80% egg length namespace: spatial_qualifier def: "70-80% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000134 name: 70-90% egg length namespace: spatial_qualifier def: "70-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000135 name: 80% egg length namespace: spatial_qualifier def: "80% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000136 name: 80-90% egg length namespace: spatial_qualifier def: "80-90% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000137 name: 90% egg length namespace: spatial_qualifier def: "90% of egg length from the posterior tip of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000139 name: 90-100% egg length namespace: spatial_qualifier alt_id: FBcv:0000138 def: "90-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] synonym: "90-100% egg length" RELATED [] is_a: FBcv:0000074 ! egg length [Term] id: FBcv:0000140 name: FlyBase analysis namespace: pub_type def: "A record of an analysis carried out by FlyBase that has not been formally published." [FBC:SM] is_a: FBcv:0000233 ! unpublished [Term] id: FBcv:0000141 name: gradient namespace: spatial_qualifier def: "Expression pattern which varies in intensity following a gradient in a specific axis." [FBC:MMC] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000142 name: anterior posterior gradient namespace: spatial_qualifier def: "Expression pattern which varies in intensity following a gradient in the anterior-posterior axis." [FBC:MMC] is_a: FBcv:0000141 ! gradient [Term] id: FBcv:0000143 name: dorsal ventral gradient namespace: spatial_qualifier def: "Expression pattern which varies in intensity following a gradient in the dorsal-ventral axis." [FBC:MMC] is_a: FBcv:0000141 ! gradient [Term] id: FBcv:0000144 name: obsolete maternal pattern is_obsolete: true [Term] id: FBcv:0000145 name: striped namespace: spatial_qualifier def: "Restricted to stripes in some specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000146 name: I-CreI namespace: origin_of_mutation def: "Sequence change caused by the cleavage of a 19-24 bp palindromic DNA site by the I-CreI endonuclease." [UniProt:P05725] synonym: "change induced by I-CreI endonuclease cleavage" EXACT [] is_a: FBcv:0003007 ! site specific cleavage [Term] id: FBcv:0000147 name: even pair rule expression pattern namespace: embryonic_pattern_qualifier def: "Expression in even, but not odd numbered segment of the blastoderm." [FBC:DOS] is_a: FBcv:0000322 ! pair rule expression pattern [Term] id: FBcv:0000148 name: odd pair rule expression pattern namespace: embryonic_pattern_qualifier def: "Expression in odd, but not even numbered segments of the blastoderm." [FBC:DOS] is_a: FBcv:0000322 ! pair rule expression pattern [Term] id: FBcv:0000149 name: species list namespace: pub_type def: "A list of species found in a specified area." [FBC:SM] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000150 name: segmentally repeated namespace: spatial_qualifier def: "Restricted to a segmentally repeated pattern with some specified type." [FBC:DOS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000151 name: obsolete archive namespace: pub_type comment: This term was obsoleted because there because there were no instances of its use to classify any artefact in FlyBase. is_obsolete: true [Term] id: FBcv:0000152 name: obsolete balancer stock def: "A stock with one or more chromosomes (balancers) that are used primarily for their ability to preserve a stock genotype without selection." [FBC:KM] comment: Consider - FBsv:0001001. is_obsolete: true [Term] id: FBcv:0000153 name: cell autonomous namespace: genotype_to_phenotype_relation def: "A phenotypic effect which is expressed in and limited to cells of the mutant genetic constitution under investigation is said to be cell autonomous." [FlyBase:FBrf0002379] is_a: FBcv:0000797 ! cell autonomy qualifier [Term] id: FBcv:0000154 name: cell non-autonomous namespace: genotype_to_phenotype_relation def: "A phenotypic effect which is not expressed in/limited to cells of the mutant genetic constitution under investigation is said to be cell non-autonomous." [FlyBase:FBrf0002379] is_a: FBcv:0000797 ! cell autonomy qualifier [Term] id: FBcv:0000155 name: single balancer def: "Chromosome that carries inversions and visible mutations, and which can be used to identify the genotype of an individual." [FlyBase:FBrf0089469, FlyBase:FBrf0202435] is_a: FBcv:0000687 ! balancer descriptor [Term] id: FBcv:0000156 name: obsolete pair of homologous balancers is_obsolete: true [Term] id: FBcv:0000157 name: obsolete recessive lethal balancer is_obsolete: true [Term] id: FBcv:0000158 name: obsolete balancer for chromosome 1 comment: Consider - FBsv:0001006. is_obsolete: true [Term] id: FBcv:0000159 name: obsolete balancer for chromosome 2 comment: Consider - FBsv:0001007. is_obsolete: true [Term] id: FBcv:0000160 name: obsolete balancer for chromosome 3 comment: Consider - FBsv:0001008. is_obsolete: true [Term] id: FBcv:0000161 name: maternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a maternal effect when the phenotype of an individual is a manifestation of the genotype of the mother, rather than the genotype of the individual." [ISBN:978-0-7167-3520-5] is_a: FBcv:0000685 ! parental effect [Term] id: FBcv:0000162 name: non-rescuable maternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a non-rescuable maternal effect (strict maternal effect) when the introduction of a wild-type copy of the responsible mutation from the father has no ameliorating effect on the maternal effect mutant phenotype." [FlyBase:FBrf0049894] is_a: FBcv:0000161 ! maternal effect [Term] id: FBcv:0000163 name: rescuable maternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a rescuable maternal effect when the introduction of a wild-type copy of the responsible mutation from the father ameliorates the maternal effect mutant phenotype." [FlyBase:FBrf0049894] is_a: FBcv:0000161 ! maternal effect [Term] id: FBcv:0000164 name: paternal effect namespace: genotype_to_phenotype_relation def: "A phenotypic attribute is described as showing a paternal effect when the phenotype of an individual is a manifestation of the genotype of the father, rather than the genotype of the individual." [FlyBase:FBrf0102738] is_a: FBcv:0000685 ! parental effect [Term] id: FBcv:0000165 name: obsolete pair of balancers for chromosome 2 is_obsolete: true [Term] id: FBcv:0000166 name: morphological qualifier namespace: expression_qualifier def: "Qualifier that describes an observed expression pattern." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000167 name: faint namespace: expression_qualifier def: "Weak expression." [FBC:MMC] is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000168 name: granular namespace: expression_qualifier def: "Expression pattern that resembles small grains or particles." [FBC:MMC] xref: PATO:0001759 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000169 name: intense namespace: expression_qualifier def: "Strong expression." [FBC:MMC] xref: PATO:0000049 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000170 name: punctate namespace: expression_qualifier def: "Expression pattern that resembles small dots." [FBC:MMC] xref: PATO:0001512 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000171 name: uniform namespace: expression_qualifier def: "Expression pattern that is constant throughout the assayed anatomical entity." [FBC:MMC] xref: PATO:0000438 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000172 name: variable namespace: expression_qualifier def: "Expression pattern that changes throughout the assayed anatomical entity." [FBC:MMC] xref: PATO:0001227 is_a: FBcv:0000166 ! morphological qualifier [Term] id: FBcv:0000173 name: obsolete pair of balancers for chromosome 3 is_obsolete: true [Term] id: FBcv:0000174 name: obsolete dominant male sterile balancer comment: Consider - FBsv:0001012. is_obsolete: true [Term] id: FBcv:0000175 name: obsolete dominant female sterile balancer comment: Consider - FBsv:0001012. is_obsolete: true [Term] id: FBcv:0000176 name: temporal qualifier namespace: temporal_qualifier subset: do_not_annotate is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000177 name: obsolete dominant female sterile balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000178 name: obsolete early namespace: temporal_qualifier comment: This term was obsoleted because a term from the developmental ontology (FBdv) should be used instead [FBC:MMC]. mc161027 xref: PATO:0000694 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000179 name: obsolete dominant female sterile balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000180 name: obsolete dominant male sterile balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000181 name: obsolete late namespace: temporal_qualifier comment: This term was obsoleted because a term from the developmental ontology (FBdv) should be used instead [FBC:MMC]. mc161027 xref: PATO:0000502 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000182 name: obsolete mid namespace: temporal_qualifier comment: This term was obsoleted because a term from the developmental ontology (FBdv) should be used instead [FBC:MMC]. mc161027 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000183 name: obsolete n day comment: This term has been obsoleted because there are new stage terms that can be used instead [FBC:MMC]. mc160113 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000184 name: obsolete n hr comment: This term has been obsoleted because there are new stage terms that can be used instead [FBC:MMC]. mc160113 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000185 name: obsolete dominant male sterile balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000186 name: obsolete recessive lethal balancer for chromosome 1 is_obsolete: true [Term] id: FBcv:0000187 name: obsolete recessive lethal balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000188 name: publication descriptor def: "Qualifier that describes the type of publication." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000013 ! descriptor [Term] id: FBcv:0000189 name: publication class namespace: pub_type def: "A publicly available document. It includes individual articles, such as research papers and reviews, and collections of articles, such as scientific journals." [FBC:DOS, FBC:SM] subset: do_not_annotate is_a: FBcv:0000188 ! publication descriptor [Term] id: FBcv:0000190 name: abstract namespace: pub_type def: "An individual abstract of a presentation at a meeting, congress, conference, symposium, colloquium, seminar, workshop, round table, or other professional gathering." [MeSH:D016416] synonym: "Meeting Abstracts" EXACT [MeSH:D016416] xref: MeSH:D016416 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000191 name: obsolete advertisement namespace: pub_type comment: This term was obsoleted because it only ever used to annotate a couple of publications. is_obsolete: true [Term] id: FBcv:0000192 name: autobiography namespace: pub_type def: "A work consisting of a self-described account." [MeSH:D020493] xref: MeSH:D020493 is_a: FBcv:0000194 ! biography [Term] id: FBcv:0000193 name: bibliographic list namespace: pub_type def: "A work consisting of a list of books, articles, documents, publications, and other items, usually on a single subject or related subjects." [MeSH:D016417] synonym: "Bibliography" EXACT [MeSH:D016417] xref: MeSH:D016417 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000194 name: biography namespace: pub_type def: "A work consisting of an account of the events, works, and achievements, personal and professional, during a person's life. This class includes articles on the activities and accomplishments of living persons as well as the presentation of an obituary." [MeSH:D019215] xref: MeSH:D019215 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000195 name: book namespace: pub_type def: "A publication on a single subject or related subjects that is complete in itself, whether constructed of chapters, sections, or parts, and that is not issued on a regular, ongoing basis. Every chapter is written by the same author or authors of the publication." [FBC:SM] comment: For books (in the common sense of the term) that have different authors for each chapter, please use 'edited book'. is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000196 name: obsolete booklet namespace: pub_type comment: This term was obsoleted because it was little used in curation. The formerly associated publications have mainly been annotated with other, more appropriate publication classes. is_obsolete: true [Term] id: FBcv:0000197 name: book review namespace: pub_type def: "A work consisting of a critical analysis of one or more books or other monographic works." [MeSH:D022921] synonym: "Book Reviews" EXACT [MeSH:D022921] xref: MeSH:D022921 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000198 name: obsolete computer file namespace: pub_type synonym: "CD-ROM" RELATED [] is_obsolete: true [Term] id: FBcv:0000199 name: conference report namespace: pub_type def: "The published records of the papers delivered at or issued on the occasion of individual congresses, symposia, and meetings; abstracts of papers delivered at such congresses; reports of the officers and delegates of such congresses; combinations of the foregoing; or proceedings of the conference of a society if they are not limited to matters of internal organization." [MeSH:D016423] comment: The definition is taken straight from the MeSH term Congresses, which PubMed uses to annotate both meeting reports written by attendees and conference abstract books. This term should therefore be used to index both of these two rather different artefacts. synonym: "conference proceedings" NARROW [] synonym: "Congresses" EXACT [MeSH:D016423] synonym: "meeting report" NARROW [] xref: MeSH:D016423 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000200 name: obsolete demonstration namespace: pub_type comment: This term was obsoleted because it was little used. All publications associated with it have been re-annotated with other publication classes. is_obsolete: true [Term] id: FBcv:0000201 name: DNA/RNA sequence record namespace: pub_type def: "A record of a DNA or RNA sequence in some standard format, such as GenBank or EMBL or DDBJ." [FBC:DOS, FBC:SM] is_a: FBcv:0000789 ! sequence record [Term] id: FBcv:0000202 name: protein sequence record namespace: pub_type def: "A record of a protein sequence in some standard format, such as UniProtKB." [FBC:SM] is_a: FBcv:0000789 ! sequence record [Term] id: FBcv:0000203 name: erratum namespace: pub_type def: "A work consisting of an acknowledgement of an error, issued by a publisher, editor, or author." [MeSH:D016425] synonym: "correction" EXACT [] synonym: "Corrigendum" EXACT [MeSH:D016425] synonym: "Published Erratum" EXACT [MeSH:D016425] xref: MeSH:D016425 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000204 name: film namespace: pub_type def: "A film or video that is factual, documentary or instructional in character." [FBC:SM, MeSH:D019499, MeSH:D019514] synonym: "video" NARROW [] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000205 name: interview namespace: pub_type def: "A work consisting of a conversation with an individual regarding his or her background and other personal and professional details, opinions on specific subjects posed by the interviewer." [MeSH:D017203] xref: MeSH:D017203 is_a: FBcv:0000194 ! biography [Term] id: FBcv:0000206 name: obsolete jigsaw puzzle namespace: pub_type comment: This term was obsoleted because it only ever used to annotate one, unarchived publication. is_obsolete: true [Term] id: FBcv:0000207 name: letter namespace: pub_type def: "A work consisting of written or printed communication between individuals or between persons and representatives of corporate bodies. The correspondence may be personal or professional." [MeSH:D016422] comment: In medical and other scientific publications the letter is usually from one or more authors to the editor of the journal or book publishing the item being commented upon or discussed. xref: MeSH:D016422 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000208 name: obsolete microscope slides namespace: pub_type comment: This term was obsoleted because it had only been used once in FlyBase, and this was for an artefact that is not present in a FlyBase associated archive. The associated record in FlyBase CHADO has been obsoleted. is_obsolete: true [Term] id: FBcv:0000209 name: news article namespace: pub_type def: "A work consisting of an announcement or statement of recent or current events of new data and matters of interest in the field of medicine or science, published in a scientific journal." [FBC:SM, MeSH:D016433] xref: MeSH:D016433 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000210 name: note namespace: pub_type def: "A work consisting of a critical or explanatory note written to discuss, support, or dispute an article or other presentation previously published." [MeSH:D016420] synonym: "Comment" EXACT [MeSH:D016420] xref: MeSH:D016420 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000211 name: obituary namespace: pub_type def: "A published announcement of a death accompanied by a short biography of the deceased." [FBC:SM] is_a: FBcv:0000194 ! biography [Term] id: FBcv:0000212 name: paper namespace: pub_type def: "An article reporting original research, published in a peer-reviewed journal." [FBC:SM] comment: Note that this is a much more specific class than that referred to by MeSH Journal article (D016428). synonym: "Journal article" BROAD [MeSH:D016428] xref: MeSH:D016428 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000213 name: patent namespace: pub_type def: "A work consisting of documents granted by a government giving exclusive rights to an inventor or assignee to manufacture, use, or sell an invention for a certain number of years." [MeSH:D020490] xref: MeSH:D020490 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000214 name: personal communication to FlyBase namespace: pub_type def: "A work that has not been formally published and that consists of observations or data submitted by a researcher or group of researchers directly to FlyBase." [FBC:DOS, FBC:SM] is_a: FBcv:0000233 ! unpublished [Term] id: FBcv:0000215 name: poem namespace: pub_type def: "A literary or oral work expressing meaning via symbolism and following formal or informal patterns." [MeSH:D055821] synonym: "poetry" EXACT [MeSH:D055821] xref: MeSH:D055821 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000216 name: poster namespace: pub_type def: "A work consisting of a single or multi-sheet notice made to attract attention to events, activities, causes, goods, or services. It is for posting, usually in a public place and is chiefly pictorial. It is intended to make an immediate impression from a distance." [MeSH:D019519] comment: The class does not encompass poster presentations at conferences and meetings. xref: MeSH:D019519 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000217 name: press release namespace: pub_type def: "A written or recorded communication directed at members of the news media for the purpose of announcing something ostensibly newsworthy." [http://en.wikipedia.org/w/index.php?title=Press_release&oldid=482495713] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000218 name: obsolete recording namespace: pub_type comment: This term has been obsoleted because it was little used in curation and the artefacts annotated with it are not present in any FlyBase associated archive. Records annotated with this term have been obsoleted in the FlyBase CHADO database. is_obsolete: true [Term] id: FBcv:0000219 name: retraction namespace: pub_type def: "A work consisting of a statement issued by one or more authors of an article or a book, withdrawing or disavowing acknowledgement of their participation in performing research or writing the results of their study." [MeSH:D016440] synonym: "Retraction of Publication" EXACT [MeSH:D016440] xref: MeSH:D016440 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000220 name: review namespace: pub_type def: "An article or book published after examination of published material on a subject." [MeSH:D016454] comment: The reviews most often desired are reviews of the current literature, but a review of historical literature is also within the scope of this publication type. xref: MeSH:D016454 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000221 name: obsolete slides namespace: pub_type comment: This term has been obsoleted because it was little used in curation and the artefacts annotated with it are not present in any FlyBase associated archive. is_obsolete: true [Term] id: FBcv:0000222 name: spoof namespace: pub_type def: "A mildly satirical mockery or parody of a conventional publication type." [FBC:SM] xref: MeSH:D020480 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000223 name: stock list namespace: pub_type def: "A list of Drosophila stocks kept by a specified stock center or research group." [FBC:SM] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000224 name: supplementary material namespace: pub_type def: "Supporting content or information, such as animation, datasets, multimedia files, video, movies, audio files, text files, or software, which is submitted for publication in an online journal or an online edition of a journal. This information may be referenced in the text of the article with a link to the supplementary data provided." [MeSH:D058537] synonym: "additional files" EXACT [] synonym: "Electronic Supplementary Materials" EXACT [MeSH:D058537] synonym: "supplementary information" EXACT [] synonym: "supporting information" EXACT [] xref: MeSH:D058537 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000225 name: obsolete T-shirt namespace: pub_type comment: This term was obsoleted because it had been used only once in ~20 years of curation. is_obsolete: true [Term] id: FBcv:0000226 name: obsolete tactile diagram namespace: pub_type def: "A diagram that is designed to be touched, rather than looked at. These are generally made for use by blind or visually impaired people." [FBC:DOS] is_obsolete: true [Term] id: FBcv:0000227 name: teaching note namespace: pub_type def: "An article describing exercises or practicals suitable for teaching." [FBC:SM] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000228 name: thesis namespace: pub_type def: "A work consisting of a formal presentation made usually to fulfill requirements for an academic degree." [MeSH:D019478] synonym: "Academic Dissertations" EXACT [MeSH:D019478] xref: MeSH:D019478 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000229 name: curated genome annotation namespace: pub_type def: "A systematic effort to annotate gene models on a sequenced Drosophila genome, such as those conducted for D. melanogaster at the Celera Jamboree. Annotations may be performed manually or automatically." [FBC:SM] comment: Note that the name of this publication type will change to simply 'genome annotation', but this change has been delayed pending required work on the database. synonym: "automatic genome annotation" RELATED [] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000230 name: obsolete automatic genome annotation namespace: pub_type comment: This term was obsoleted because it was hardly ever used. Please use FBcv:0000229 instead. is_obsolete: true replaced_by: FBcv:0000229 [Term] id: FBcv:0000231 name: white paper namespace: pub_type def: "A work consisting of a set of statements, directions, or principles presenting current or future rules or policy." [FBC:SM, MeSH:D016431] synonym: "Guideline" BROAD [MeSH:D016431] xref: MeSH:D016431 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000232 name: obsolete recessive lethal balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000233 name: unpublished namespace: pub_type def: "A work that has not been formally published." [MeSH:D022902] synonym: "privately distributed report" RELATED [] synonym: "Unpublished Works" EXACT [MeSH:D022902] xref: MeSH:D022902 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000234 name: publication language namespace: language def: "Qualifier that describes the language of the publication." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000188 ! publication descriptor [Term] id: FBcv:0000235 name: Afrikaans namespace: language def: "Publication in the Afrikaans language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000236 name: Arabic namespace: language def: "Publication in the Arabic language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000237 name: Armenian namespace: language def: "Publication in the Armenian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000238 name: Belarussian namespace: language def: "Publication in the Belarussian language." [FBC:MMC] synonym: "Belarusian" RELATED [] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000239 name: Bulgarian namespace: language def: "Publication in the Bulgarian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000240 name: Catalan namespace: language def: "Publication in the Catalan language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000241 name: Chinese namespace: language def: "Publication in the Chinese language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000242 name: Cumbrian namespace: language def: "Publication in the Cumbrian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000243 name: Czech namespace: language def: "Publication in the Czech language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000244 name: Danish namespace: language def: "Publication in the Danish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000245 name: Dutch namespace: language def: "Publication in the Dutch language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000246 name: English namespace: language def: "Publication in the English language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000247 name: Estonian namespace: language def: "Publication in the Estonian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000248 name: Faroese namespace: language def: "Publication in the Faroese language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000249 name: Farsi namespace: language def: "Publication in the Farsi language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000250 name: Finnish namespace: language def: "Publication in the Finnish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000251 name: Flemish namespace: language def: "Publication in the Flemish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000252 name: French namespace: language def: "Publication in the French language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000253 name: German namespace: language def: "Publication in the German language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000254 name: Greek namespace: language def: "Publication in the Greek language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000255 name: Hebrew namespace: language def: "Publication in the Hebrew language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000256 name: Hungarian namespace: language def: "Publication in the Hungarian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000257 name: Icelandic namespace: language def: "Publication in the Icelandic language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000258 name: Indonesian namespace: language def: "Publication in the Indonesian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000259 name: Italian namespace: language def: "Publication in the Italian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000260 name: Japanese namespace: language def: "Publication in the Japanese language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000261 name: Jugoslavian namespace: language def: "Publication in the Jugoslavian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000262 name: Korean namespace: language def: "Publication in the Korean language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000263 name: Latin namespace: language def: "Publication in the Latin language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000264 name: Latvian namespace: language def: "Publication in the Latvian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000265 name: Lithuanian namespace: language def: "Publication in the Lithuanian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000266 name: Malay namespace: language def: "Publication in the Malay language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000267 name: Malayalam namespace: language def: "Publication in the Malayalam language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000268 name: Norwegian namespace: language def: "Publication in the Norwegian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000269 name: Polish namespace: language def: "Publication in the Polish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000270 name: Portuguese namespace: language def: "Publication in the Portuguese language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000271 name: Serbo-Croat(Roman) namespace: language def: "Publication in the Serbo-Croat (Roman) language." [FBC:MMC] is_a: FBcv:0000274 ! Serbo-Croat [Term] id: FBcv:0000272 name: Romanian namespace: language def: "Publication in the Roman language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000273 name: Russian namespace: language def: "Publication in the Russian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000274 name: Serbo-Croat namespace: language def: "Publication in the Serbo-Croat language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000275 name: Slovak namespace: language def: "Publication in the Slovak language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000276 name: Slovenian namespace: language def: "Publication in the Slovenian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000277 name: Spanish namespace: language def: "Publication in the Spanish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000278 name: Swedish namespace: language def: "Publication in the Swedish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000279 name: Turkish namespace: language def: "Publication in the Turkish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000280 name: Ukrainian namespace: language def: "Publication in the Ukrainian language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000281 name: Yiddish namespace: language def: "Publication in the Yiddish language." [FBC:MMC] is_a: FBcv:0000234 ! publication language [Term] id: FBcv:0000282 name: mutant scorability rank namespace: scorability def: "Rank that describes the usefulness of mutants according to their phenotype." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000283 name: RK1 namespace: scorability def: "The RK1 rank describes mutants that are easily scored." [FlyBase:FBrf0066905] is_a: FBcv:0000282 ! mutant scorability rank [Term] id: FBcv:0000284 name: RK2 namespace: scorability def: "The RK2 rank describes mutants that are usable but less convenient." [FlyBase:FBrf0066905] is_a: FBcv:0000282 ! mutant scorability rank [Term] id: FBcv:0000285 name: RK3 namespace: scorability def: "The RK3 rank describes mutants that are of limited usefulness." [FlyBase:FBrf0066905] is_a: FBcv:0000282 ! mutant scorability rank [Term] id: FBcv:0000286 name: allele class namespace: allele_class def: "Term that describes the type of allele." [FBC:MMC] subset: do_not_annotate synonym: "allele morphy class" EXACT [] is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000287 name: loss of function allele namespace: allele_class def: "An allele that either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type." [FlyBase:FBrf0049147] comment: Loss of function alleles are generally, but not exclusively, recessive. At haplo-insufficient loci (loci that require two copies for normal function), loss of function alleles can be dominant. is_a: FBcv:0000286 ! allele class [Term] id: FBcv:0000288 name: amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function from the observation that addition of extra copies in the genome has no effect on the phenotype. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000688 ! amorphic allele [Term] id: FBcv:0000289 name: hypomorphic allele - genetic evidence namespace: allele_class def: "Allele inferred to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity from the observation that extra copies in the genome decrease the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype than the allele in trans to a deletion of the gene (1 copy))." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000690 ! hypomorphic allele [Term] id: FBcv:0000290 name: gain of function allele namespace: allele_class def: "An allele that either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FlyBase:FBrf0049147] comment: Gain of function alleles are generally dominant. But not all dominant alleles are gain of function alleles. is_a: FBcv:0000286 ! allele class [Term] id: FBcv:0000291 name: neomorphic allele - genetic evidence namespace: allele_class def: "An allele that is inferred to make a gene product with a novel function or expression pattern compared to wild-type based on the evidence that the phenotype is unaffected by extra or fewer doses of the wild-type gene." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000697 ! neomorphic allele [Term] id: FBcv:0000292 name: antimorphic allele - genetic evidence namespace: allele_class def: "An allele that is inferred to make a gene product that is antagonistic to the wild-type gene product from the observations that extra copies of the wild-type allele reduce the expressivity and/or penetrance of the phenotype. So, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus. This test is similar to that used for hypomorphic alleles. An antimorph can be distinguished from a dominant hypermorph as only the former can be reverted to wild-type by deletion of the mutant allele." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000695 ! antimorphic allele [Term] id: FBcv:0000293 name: hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type from the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype. Most commonly this evidence takes the form of experiments showing that homozygotes (2 copies) have a stronger phenotype than transheterozygotes to a deletion of the gene (1 copy)." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000696 ! hypermorphic allele [Term] id: FBcv:0000294 name: wild-type allele namespace: allele_class def: "Allele that corresponds to the wild-type one." [FBC:MMC] is_a: FBcv:0000286 ! allele class [Term] id: FBcv:0000295 name: wild-type generic namespace: allele_class def: "Wild-type allele that can be distinguished from others." [FBC:MMC] is_a: FBcv:0000294 ! wild-type allele [Term] id: FBcv:0000296 name: isoallele namespace: allele_class def: "Wild-type allele that can only be distinguished from another one under special conditions." [FlyBase:FBrf0202435] is_a: FBcv:0000294 ! wild-type allele [Term] id: FBcv:0000297 name: obsolete extracted wild-type chromosome 1 is_obsolete: true [Term] id: FBcv:0000298 name: recessive namespace: dominance_qualifier def: "A phenotypic attribute is described as recessive when it is manifest only in individuals homozygous or hemizygous for the allele that causes that phenotype." [ISBN:978-0-8053-0316-2] is_a: FBcv:0000565 ! dominance relationship qualifier [Term] id: FBcv:0000299 name: dominant namespace: dominance_qualifier def: "A phenotypic attribute is described as dominant when it is manifest in individuals heterozygous for the allele that causes that phenotype." [ISBN:978-0-8053-0316-2] is_a: FBcv:0000565 ! dominance relationship qualifier [Term] id: FBcv:0000300 name: codominant namespace: dominance_qualifier def: "A phenotypic attribute is described as codominant when it is manifest in individuals carrying the allele that causes that phenotype, irrespective of the homologous allele." [ISBN:978-0-8053-0316-2] is_a: FBcv:0000299 ! dominant [Term] id: FBcv:0000301 name: semidominant namespace: dominance_qualifier def: "A phenotypic attribute is described as semidominant when individuals heterozygous for the allele show phenotypes part way between homozygotes for either allele." [ISBN:978-0-8053-0316-2] is_a: FBcv:0000299 ! dominant [Term] id: FBcv:0000302 name: obsolete extracted wild-type chromosome 2 is_obsolete: true [Term] id: FBcv:0000303 name: obsolete extracted wild-type chromosome 3 is_obsolete: true [Term] id: FBcv:0000304 name: obsolete extracted wild-type chromosome 4 is_obsolete: true [Term] id: FBcv:0000305 name: obsolete extracted wild-type chromosome Y is_obsolete: true [Term] id: FBcv:0000306 name: sex limited namespace: sex_qualifier def: "Expression is limited to one or other sex by virtue of the particular biology of that sex, rather than the sex-linkage of the genes underlying the attribute." [FlyBase:FBrf0075559] comment: May be used to qualify expression of phenotypes or of genes, transgenes etc. is_a: FBcv:0000332 ! sex [Term] id: FBcv:0000307 name: male limited namespace: sex_qualifier def: "Expression is limited to males by virtue of the particular biology of males, rather than the sex-linkage of the gene(s) involved." [FlyBase:FBrf0075559] comment: May be used to qualify expression of phenotypes or of genes, transgenes etc. is_a: FBcv:0000306 ! sex limited [Term] id: FBcv:0000308 name: female limited namespace: sex_qualifier def: "Expression is limited to females by virtue of the particular biology of females, rather than the sex-linkage of the gene(s) involved." [FlyBase:FBrf0075559] comment: May be used to qualify expression of phenotypes or of genes, transgenes etc. is_a: FBcv:0000306 ! sex limited [Term] id: FBcv:0000309 name: conditional namespace: environmental_qualifier def: "Phenotype expressed only under specific environmental conditions that do not induce the same defect in wild-type animals." [FBC:DOS] synonym: "conditional qualifier" RELATED [] is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000310 name: temperature conditional namespace: environmental_qualifier def: "Phenotype only expressed in some subset of the temperature range within which wild-type animals are viable." [FBC:DOS] is_a: FBcv:0000309 ! conditional [Term] id: FBcv:0000311 name: heat sensitive namespace: environmental_qualifier def: "Phenotype only expressed at high temperatures." [FBC:DOS] synonym: "conditional - heat sensitive" EXACT [] synonym: "conditional ts" EXACT [] synonym: "hs" EXACT [] is_a: FBcv:0000310 ! temperature conditional [Term] id: FBcv:0000312 name: cold sensitive namespace: environmental_qualifier def: "Phenotype only expressed at low temperatures." [FBC:DOS] synonym: "conditional - cold sensitive" EXACT [] synonym: "conditional cs" EXACT [] synonym: "cs" EXACT [] is_a: FBcv:0000310 ! temperature conditional [Term] id: FBcv:0000313 name: drug conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of some specific drug (CHEBI:23888) whose presence does not induce the same defect in wild-type animals." [FBC:DOS] is_a: FBcv:0000704 ! chemical conditional [Term] id: FBcv:0000314 name: RU486 conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of RU486 (CHEBI:50692), also known as mifepristone." [FBC:DOS] synonym: "conditional mifepristone" EXACT [] synonym: "conditional RU486" EXACT [] is_a: FBcv:0000313 ! drug conditional [Term] id: FBcv:0000315 name: tetracycline conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of tetracycline (CHEBI:27902)." [FBC:DOS] synonym: "conditional tetracycline" EXACT [] is_a: FBcv:0000313 ! drug conditional [Term] id: FBcv:0000316 name: homeotic namespace: phenotypic_class def: "Phenotype that is the partial or full transformation of one or more segments (FBbt:00000003) or segmental appendages from one identity to another. For example, in antennapedia an antenna is partially or fully transformed into a leg." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000317 name: obsolete isogenic chromosome 1 is_obsolete: true [Term] id: FBcv:0000318 name: obsolete isogenic chromosome 2 is_obsolete: true [Term] id: FBcv:0000319 name: gap expression pattern namespace: embryonic_pattern_qualifier def: "Expression across a contiguous block of two or more segments of the blastoderm." [FBC:DOS] is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000320 name: terminal expression pattern namespace: embryonic_pattern_qualifier def: "Expression in the terminal regions of the embryo/larva: the acron, telson and adjacent segments." [FBC:DOS] synonym: "terminal" RELATED [] is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000321 name: obsolete isogenic chromosome 3 is_obsolete: true [Term] id: FBcv:0000322 name: pair rule expression pattern namespace: embryonic_pattern_qualifier def: "Expression in alternate segments of the blastoderm." [FBC:DOS] is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000323 name: segment polarity expression pattern namespace: embryonic_pattern_qualifier def: "Qualifier that describes an expression pattern of a segment polarity gene. Expression is observed in a specific location in each segment." [FBC:MMC] is_a: FBcv:0000654 ! embryonic pattern qualifier [Term] id: FBcv:0000324 name: abnormal dorsal/ventral axis specification namespace: phenotypic_class def: "Phenotype that is any abnormality in dorsal/ventral axis specification (GO:0009950). 'dorsal/ventral axis specification' is defined as: 'The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.'" [FBC:DOS, GOC:dph, GOC:go_curators, GOC:tb] synonym: "dorsal-ventral polarity" RELATED [FBC:DOS] synonym: "dorsal/ventral axis specification defective" EXACT [] is_a: FBcv:0000686 ! abnormal axis specification [Term] id: FBcv:0000325 name: neurogenic phenotype namespace: phenotypic_class def: "A phenotype that is an expansion of the developing embryonic nervous system at the expense of developing ventral epidermis." [FlyBase:FBrf0040185] comment: Typically this is caused by and expansion of the population of neuroblasts at the expense of prospective epidermis, both of which originate in the ventral ectoderm. subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2011-09-13T02:42:10Z [Term] id: FBcv:0000326 name: obsolete isogenic chromosome 4 is_obsolete: true [Term] id: FBcv:0000327 name: obsolete P-element transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000328 name: obsolete hobo transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000329 name: obsolete piggyBac transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000330 name: obsolete minos transposase source for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000331 name: obsolete polyphasic namespace: temporal_qualifier comment: This term has been obsoleted because there are new terms to replace it [FBC:MMC]. mc161027 xref: PATO:0001774 is_obsolete: true consider: FBcv:0000176 [Term] id: FBcv:0000332 name: sex namespace: sex_qualifier def: "Qualifier that relates the expression of a phenotype to the sex of the individual." [FBC:MMC] subset: do_not_annotate synonym: "sex qualifier" EXACT [FBC:DOS] is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000333 name: male namespace: sex_qualifier def: "Expressed in males." [FBC:DOS] comment: This term has historically been used as a qualifier for expression and phenotype, but its use for phenotype has been deprecated. Its use does not imply expression exclusively in males. is_a: FBcv:0000332 ! sex [Term] id: FBcv:0000334 name: female namespace: sex_qualifier def: "Expressed in females." [FBC:DOS] comment: This term has historically been used as a qualifier for expression and phenotype, but its use for phenotype has been deprecated. Its use does not imply expression exclusively in females. is_a: FBcv:0000332 ! sex [Term] id: FBcv:0000335 name: germline clone namespace: clone_qualifier def: "A clone of germline cells that share a genotype." [FBC:DOS] synonym: "germ-line clone" EXACT [] is_a: FBcv:0000812 ! clone of cells [Term] id: FBcv:0000336 name: somatic clone namespace: clone_qualifier def: "A clone of somatic cells that share a genotype that is different from the genotype of the animal in which it resides and from which it is derived." [FBC:DOS] is_a: FBcv:0000812 ! clone of cells [Term] id: FBcv:0000337 name: obsolete P-element ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000338 name: obsolete hobo ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000339 name: obsolete fully namespace: extent comment: DEPRECATION WARNING: This term has been obsoleted as 'fully' is assumed in the absence of use of 'partially'. mc151118 is_obsolete: true consider: FBcv:0000811 [Term] id: FBcv:0000340 name: partially namespace: extent def: "Incomplete penetrance or expressivity of a phenotype or incomplete suppression of a phenotype." [FBC:DOS] comment: Note on usage: This qualifier should not be used in combination with lethal, viable, sterile or fertile. For these cases, terms of the form semi-X should be used instead. is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000341 name: obsolete good namespace: intensity_qualifier comment: This term has been obsoleted as it should be assumed a phenotype is good, unless it is said otherwise, by using other qualifiers. mc151118 is_obsolete: true consider: FBcv:0000811 [Term] id: FBcv:0000342 name: poor namespace: intensity_qualifier def: "Qualifier that describes a phenotype that has poor penetrance or expressivity." [FBC:MMC] is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000343 name: reduced namespace: intensity_qualifier def: "Qualifier that describes a phenotype that has reduced penetrance or expressivity when compared to wild-type." [FBC:MMC] is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000344 name: slow namespace: intensity_qualifier def: "Qualifier that describes an electrophoretic migration of a gene product that is slower than the wild-type." [FBC:MMC] xref: PATO:0000304 is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000345 name: fast namespace: intensity_qualifier def: "Qualifier that describes an electrophoretic migration of a gene product that is intermediate in speed compared to the wild-type." [FBC:MMC] xref: PATO:0000303 is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000346 name: intermediate namespace: intensity_qualifier def: "Qualifier that describes a phenotype that is intermediate in speed compared to the wild-type." [FBC:MMC] comment: This qualifier can be used to describe an electrophoretic migration of a gene product that is intermediate in speed compared to the wild-type. is_a: FBcv:0000811 ! qualitative qualifier [Term] id: FBcv:0000347 name: phenotypic class namespace: phenotypic_class subset: do_not_annotate is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000348 name: wild-type namespace: phenotypic_class def: "The canonical phenotype of a wild-type Drosophilid." [FBC:DOS] is_a: FBcv:0000347 ! phenotypic class disjoint_from: FBcv:0001347 ! phenotype [Term] id: FBcv:0000349 name: viable namespace: phenotypic_class def: "A phenotype that is survival to mature adulthood, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS] comment: Note, this term should not be used with the qualifier 'partially'. Use semi-viable or semi-lethal instead. subset: fbcvsubset_mgiribbons is_a: FBcv:0000347 ! phenotypic class [Term] id: FBcv:0000350 name: partially lethal - majority live namespace: phenotypic_class def: "A phenotype of a population that is the death of some significant proportion of animals in that population, but less that half, prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS] subset: lethal_phase synonym: "semi-viable" EXACT [] is_a: FBcv:0000349 ! viable is_a: FBcv:0002015 ! partially lethal [Term] id: FBcv:0000351 name: lethal namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS, FBC:KM] comment: Note on usage: lethal is appropriate in cases where escaper adults are very rare. The lethal phase prior to becoming a mature adult may be further specified using children terms which specify stage. subset: lethal_phase is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0000352 name: partially lethal - majority die namespace: phenotypic_class def: "A phenotype of a population that is the death of a majority of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS, FBC:KM, FBC:NB] comment: Stages during which there is significant death prior to mature adulthood can be indicated using one or more stage qualifiers. subset: lethal_phase synonym: "semi-lethal" EXACT [] is_a: FBcv:0002015 ! partially lethal [Term] id: FBcv:0000353 name: cell lethal namespace: phenotypic_class def: "A phenotype that is a failure of mutant cells to survive." [FBC:DOS] comment: Typically, this phenotype is assayed in clones of cells. subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000354 name: visible namespace: phenotypic_class def: "A post-embryonic, macroscopic, anatomical phenotype." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000355 name: abnormal eye color namespace: phenotypic_class def: "Phenotype that is any abnormality in eye color compared to wild-type." [FBC:DOS] synonym: "eye color defective" EXACT [] synonym: "eye colour defective" EXACT [] is_a: FBcv:0000354 ! visible [Term] id: FBcv:0000356 name: abnormal body color namespace: phenotypic_class def: "A phenotype that is any abnormality in body color compared to wild-type." [FBC:DOS] synonym: "body color defective" EXACT [] synonym: "body colour defective" EXACT [] is_a: FBcv:0000354 ! visible [Term] id: FBcv:0000357 name: abnormal size namespace: phenotypic_class def: "A phenotype that is any abnormality in the size of the whole body or some body part compared to wild-type." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "size defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000358 name: decreased body size namespace: phenotypic_class def: "Phenotype that is a decrease in body size compared to identically raised wild-type controls." [FBC:DOS] synonym: "small body" EXACT [] is_a: FBcv:0000665 ! abnormal body size is_a: FBcv:0007508 ! decreased size [Term] id: FBcv:0000359 name: decreased cell number namespace: phenotypic_class def: "Phenotype that is a decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth - there may be fewer cells in an otherwise normal volume of tissue." [FBC:DOS] synonym: "reduced cell number" EXACT [] is_a: FBcv:0000709 ! abnormal cell number [Term] id: FBcv:0000360 name: decreased cell size namespace: phenotypic_class def: "Phenotype that is a decrease in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by decreased growth of a tissue - there may be more cells in an otherwise normal volume of tissue." [FBC:DOS] comment: Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells. synonym: "reduced cell size" EXACT [] is_a: FBcv:0000428 ! abnormal cell size [Term] id: FBcv:0000361 name: increased body size namespace: phenotypic_class def: "Phenotype that is an increase in body size compared to identically raised wild-type controls." [FBC:DOS] synonym: "large body" EXACT [] is_a: FBcv:0000665 ! abnormal body size is_a: FBcv:0007507 ! increased size [Term] id: FBcv:0000362 name: increased cell number namespace: phenotypic_class def: "Phenotype that is an increase in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type." [FBC:DOS] comment: This phenotype is not necessarily accompanied by overgrowth of a tissue - there may be more cells in an otherwise normal volume of tissue. It is not necessarily due to an increase in cell growth -it may be the result of an increase in the division rate at normal growth rates. It may not even be due to an increase in the cell division rate - a reduced rate of cell death while the division rate is normal could also achieve it. is_a: FBcv:0000709 ! abnormal cell number [Term] id: FBcv:0000363 name: increased cell size namespace: phenotypic_class def: "Phenotype that is an increase in the size of cells compared to wild-type." [FBC:DOS] comment: May be due to an increase in the cell growth rate or to a reduced rate of cell division along with a normal rate of cell growth. is_a: FBcv:0000428 ! abnormal cell size [Term] id: FBcv:0000364 name: sterile namespace: phenotypic_class def: "A phenotype that is the inability to produce fertilized eggs as a result of mating." [FBC:AO, FBC:CP, FBC:DOS] comment: The cause of sterility may be physical or behavioral. Note, this term should not be used with the qualifier 'partially'. Use semi-sterile or semi-fertile instead. subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000365 name: semi-sterile namespace: phenotypic_class def: "A phenotype that is a reduction in the ability to produce fertilized eggs as a result of mating to below 50% of wild-type." [FBC:AO, FBC:CP, FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000366 name: female sterile namespace: phenotypic_class def: "A phenotype that is the inability of females to produce fertilized eggs as a result of mating." [FBC:AO, FBC:CP, FBC:DOS] comment: The cause of sterility may be physical or behavioral. Note: this term should not be used with the qualifier 'partially' - use semi-sterile or semi-fertile instead. is_a: FBcv:0000364 ! sterile [Term] id: FBcv:0000367 name: female semi-sterile namespace: phenotypic_class def: "A phenotype that is a reduction in the ability of females to produce fertilized eggs as a result of mating to below 50% of wild-type." [FBC:AO, FBC:CP, FBC:DOS] is_a: FBcv:0000365 ! semi-sterile [Term] id: FBcv:0000368 name: female sterile germline-dependent namespace: phenotypic_class def: "A phenotype of female sterility due to defects in the female germline." [FBC:DOS] synonym: "female sterile germ-line-dependent" EXACT [] is_a: FBcv:0000366 ! female sterile [Term] id: FBcv:0000369 name: female sterile soma-dependent namespace: phenotypic_class def: "A phenotype of female sterility due to defects in somatic cells of the ovary (FBbt:00006030), or of the products of these cells (such as eggshell)." [FBC:DOS] is_a: FBcv:0000366 ! female sterile [Term] id: FBcv:0000370 name: male sterile namespace: phenotypic_class def: "A phenotype that is the inability of males to produce fertilized eggs as a result of mating." [FBC:AO, FBC:CP, FBC:DOS] comment: The cause of sterility may be physical or behavioral. Note - this term should not be used with the qualifier 'partially' - use semi-sterile or semi-fertile instead. is_a: FBcv:0000364 ! sterile [Term] id: FBcv:0000371 name: male semi-sterile namespace: phenotypic_class def: "A phenotype that is a reduction in the ability of males to produce fertilized eggs as a result of mating to below 50% of wild-type." [FBC:AO, FBC:CP, FBC:DOS] is_a: FBcv:0000365 ! semi-sterile [Term] id: FBcv:0000372 name: male sterile germline-dependent namespace: phenotypic_class def: "A phenotype of male sterility due to defects in the male germline." [FBC:DOS] synonym: "male sterile germ-line-dependent" EXACT [] is_a: FBcv:0000370 ! male sterile [Term] id: FBcv:0000373 name: male sterile soma-dependent namespace: phenotypic_class def: "A phenotype of male sterility due to defects in somatic cells of the testis (FBbt:00006031) or of the products of these cells." [FBC:DOS] is_a: FBcv:0000370 ! male sterile [Term] id: FBcv:0000374 name: fertile namespace: phenotypic_class def: "A phenotype that is the ability to produce fertilized eggs as a result of mating." [FBC:AO, FBC:CP, FBC:DOS] comment: Note, this term should not be used with the qualifier 'partially'. Use semi-sterile or semi-fertile instead. subset: fbcvsubset_mgiribbons is_a: FBcv:0000347 ! phenotypic class [Term] id: FBcv:0000375 name: semi-fertile namespace: phenotypic_class def: "A phenotype that is a reduction in the ability to produce fertilized eggs as a result of mating, but only to > 50% of wild-type." [FBC:AO, FBC:CP, FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0000374 ! fertile is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000376 name: male fertile namespace: phenotypic_class def: "A phenotype that is the ability of males to produce fertilized eggs as a result of mating." [FBC:AO, FBC:CP, FBC:DOS] comment: Note - this term should not be used with the qualifier 'partially' - use male semi-sterile or male semi-fertile instead. is_a: FBcv:0000374 ! fertile [Term] id: FBcv:0000377 name: female fertile namespace: phenotypic_class def: "A phenotype that is the ability of females to produce fertilized eggs as a result of mating." [FBC:AO, FBC:CP, FBC:DOS] comment: Note - this term should not be used with the qualifier 'partially' - use female semi-sterile or female semi-fertile instead. is_a: FBcv:0000374 ! fertile [Term] id: FBcv:0000378 name: grandchildless namespace: phenotypic_class def: "A phenotype in which all offspring are sterile. Typically, this is due to maternal effect sterility resulting from defects in pole cell development." [ISBN:978-0-87969-321-3] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000379 name: enhancer of variegation namespace: phenotypic_class def: "Genotype g1 is an enhancer of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is greater than that caused by g2 alone." [FBC:DOS] comment: Typically, g2 is a chromosomal aberration or an insertion. is_a: FBcv:0000008 ! modifier of variegation [Term] id: FBcv:0000380 name: non-enhancer of variegation namespace: phenotypic_class def: "Genotype g1 is a non-enhancer of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not greater than that caused by g2 alone." [FBC:DOS] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000381 name: suppressor of variegation namespace: phenotypic_class def: "Genotype g1 is a suppressor of variegation if, and only if, some genotype g2 has a variegated phenotype and the degree of variegation caused by g1g2 is less than that caused by to g2 alone." [FBC:DOS] comment: Typically, g2 is a chromosomal aberration or an insertion. is_a: FBcv:0000008 ! modifier of variegation [Term] id: FBcv:0000382 name: non-suppressor of variegation namespace: phenotypic_class def: "Genotype g1 is a non-suppressor of variegation of the phenotype due to genotype g2 if, and only if, g2 has a variegated phenotype and the degree of variegation caused by g1g2 is not less than that caused by g2 alone." [FBC:DOS] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000383 name: auxotroph namespace: phenotypic_class def: "A phenotype that is the inability to synthesize some organic compound that can be synthesized by wild-type animals, and that is required for normal growth and/or development." [http://en.wikipedia.org/wiki/Auxotrophic] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000384 name: abnormal aging namespace: phenotypic_class def: "Phenotype that is any abnormality in aging (GO:0007568). 'aging' is defined as: 'A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).'" [GOC:PO_curators] subset: fbcvsubset_mgiribbons synonym: "aging defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000385 name: short lived namespace: phenotypic_class def: "Phenotype that is a shorter adult life-span than wild-type." [FBC:DOS] subset: lethal_phase synonym: "increased adult mortality" EXACT [] is_a: FBcv:0002004 ! increased mortality [Term] id: FBcv:0000386 name: long lived namespace: phenotypic_class def: "Phenotype that is a longer adult life-span than wild-type." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000387 name: abnormal behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in behavior (GO:0007610). 'behavior' is defined as: 'The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.'" [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973] subset: fbcvsubset_mgiribbons synonym: "behavior defective" EXACT [] synonym: "behavioral" RELATED [] synonym: "behaviour defective" EXACT [] synonym: "behavioural" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000388 name: abnormal gravitaxis namespace: phenotypic_class def: "Phenotype that is a change in the strong tendency, seen in wild-type Drosophila melanogaster, to climb - a behavior otherwise known as negative gravitaxis (GO:0048060 ; movement away from the source of gravity)." [FBC:DOS] comment: Note, this term should not be used when flies have climbing defects purely as a consequence of locomotion defects, use 'locomotor behavior defective' instead. subset: fbcvsubset_mgiribbons synonym: "geotaxis behaviour defective" RELATED [] synonym: "gravitaxis behavior defective" RELATED [] synonym: "gravitaxis defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000389 name: paralytic namespace: phenotypic_class def: "Phenotype that is a disposition to paralysis under conditions that do not cause paralysis in a wild-type animal. Paralysis is defined as an inability to exhibit `multicellular organismal movement` (GO:0050879)" [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000390 name: hypoactive namespace: phenotypic_class def: "A phenotype consisting of decreased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000391 name: bang sensitive namespace: phenotypic_class def: "A phenotype exhibited following mechanical shock and consisting of a brief period of intense, uncoordinated motor activity (legs and wings flailing, abdomen coiling) followed by a prolonged period of paralysis." [FlyBase:FBrf0022877] synonym: "easily shocked" RELATED [FlyBase:FBrf0022877] is_a: FBcv:0000389 ! paralytic [Term] id: FBcv:0000392 name: hyperactive namespace: phenotypic_class def: "A phenotype consisting of increased frequency of `multicellular organismal movement` (GO:0050879) compared to wild-type." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000393 name: abnormal pain response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to pain (GO:0048265). 'response to pain' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.'" [FBC:DOS, GOC:jid, PMID:10203867, PMID:12723742, PMID:12843304, Wikipedia:Pain] synonym: "pain response defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response [Term] id: FBcv:0000394 name: abnormal circadian rhythm namespace: phenotypic_class def: "Phenotype that is any abnormality in circadian rhythm (GO:0007623). 'circadian rhythm' is defined as: 'Any biological process in an organism that recurs with a regularity of approximately 24 hours.'" [FBC:DOS, GOC:bf, GOC:go_curators] subset: fbcvsubset_mgiribbons synonym: "circadian rhythm defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000395 name: abnormal locomotor rhythm namespace: phenotypic_class def: "Phenotype that is any abnormality in locomotor rhythm (GO:0045475). 'locomotor rhythm' is defined as: 'The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.'" [FBC:DOS, GOC:go_curators] synonym: "locomotor rhythm defective" EXACT [] is_a: FBcv:0000414 ! abnormal locomotor behavior is_a: FBcv:0000679 ! abnormal circadian behavior [Term] id: FBcv:0000396 name: abnormal eclosion rhythm namespace: phenotypic_class def: "Phenotype that is any abnormality in eclosion rhythm (GO:0008062). 'eclosion rhythm' is defined as: 'The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.'" [FBC:DOS, PMID:11715043] synonym: "eclosion rhythm defective" EXACT [] is_a: FBcv:0000670 ! abnormal eclosion is_a: FBcv:0000679 ! abnormal circadian behavior [Term] id: FBcv:0000397 name: abnormal learning namespace: phenotypic_class def: "Phenotype that is any abnormality in learning (GO:0007612). 'learning' is defined as: 'Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.'" [FBC:DOS, ISBN:0582227089, ISBN:0721662544] synonym: "learning defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000398 name: abnormal memory namespace: phenotypic_class def: "Phenotype that is any abnormality in memory (GO:0007613). 'memory' is defined as: 'The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).'" [FBC:DOS, GOC:curators, ISBN:0582227089] synonym: "memory defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000399 name: abnormal courtship behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in courtship behavior (GO:0007619). 'courtship behavior' is defined as: 'The behavior of an organism for the purpose of attracting sexual partners.'" [FBC:DOS, GOC:ai, GOC:dph] synonym: "courtship behavior defective" EXACT [] is_a: FBcv:0000721 ! abnormal mating behavior [Term] id: FBcv:0000400 name: abnormal mating namespace: phenotypic_class def: "Phenotype that is any abnormality in mating (GO:0007618). 'mating' is defined as: 'The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.'" [FBC:DOS, GOC:jl, ISBN:0387520546] subset: fbcvsubset_mgiribbons synonym: "mating defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000401 name: abnormal mating rhythm namespace: phenotypic_class def: "Phenotype that is any abnormality in circadian mating behavior (GO:0035648). 'circadian mating behavior' is defined as: 'The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.'" [FBC:DOS, GOC:bf, GOC:dos, PMID:11470898, PMID:17276917] synonym: "mating rhythm defective" EXACT [] is_a: FBcv:0000679 ! abnormal circadian behavior is_a: FBcv:0000721 ! abnormal mating behavior [Term] id: FBcv:0000402 name: abnormal song namespace: phenotypic_class def: "Phenotype that is any abnormality in male courtship behavior, veined wing generated song production (GO:0045433). This is defined as 'The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.'" [FBC:DOS, GOC:mtg_sensu, PMID:11092827] synonym: "singing defective" EXACT [FBC:SM] synonym: "song defective" EXACT [] synonym: "song production defective" EXACT [FBC:SM] is_a: FBcv:0000399 ! abnormal courtship behavior [Term] id: FBcv:0000403 name: abnormal chemosensitive behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in chemosensory behavior (GO:0007635). 'chemosensory behavior' is defined as: 'Behavior that is dependent upon the sensation of chemicals.'.'" [FBC:DOS, GOC:go_curators] synonym: "chemosensitive behavior defective" EXACT [] synonym: "chemosensitive behaviour defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000404 name: abnormal smell perception namespace: phenotypic_class def: "Phenotype that is any abnormality in sensory perception of smell (GO:0007608). 'sensory perception of smell' is defined as: 'The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.'" [FBC:DOS, GOC:ai] synonym: "olfaction defective" EXACT [] synonym: "smell perception defective" EXACT [] is_a: FBcv:0000681 ! abnormal sensory perception [Term] id: FBcv:0000405 name: abnormal taste perception namespace: phenotypic_class def: "Phenotype that is any abnormality in sensory perception of taste (GO:0050909). 'sensory perception of taste' is defined as: 'The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.'" [FBC:DOS, GOC:ai] synonym: "gustation defective" EXACT [] synonym: "taste defective" EXACT [] synonym: "taste perception defective" EXACT [] is_a: FBcv:0000681 ! abnormal sensory perception [Term] id: FBcv:0000406 name: abnormal tarsal response namespace: phenotypic_class def: "Phenotype that is any abnormality in or absense of proboscis extension reflex in response to a sugar stimulus via taste sensilla on the tarsus." [FBC:DOS] synonym: "tarsal response defective" EXACT [] is_a: FBcv:0000680 ! abnormal proboscis extension reflex [Term] id: FBcv:0000407 name: abnormal auditory perception namespace: phenotypic_class def: "Phenotype that is any abnormality in sensory perception of sound (GO:0007605). 'sensory perception of sound' is defined as: 'The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.'" [FBC:DOS, GOC:ai] synonym: "auditory perception defective" EXACT [] synonym: "auditory system defective" RELATED [] is_a: FBcv:0000681 ! abnormal sensory perception [Term] id: FBcv:0000408 name: abnormal stress response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to stress (GO:0006950). 'response to stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).'" [FBC:DOS, GOC:mah] subset: fbcvsubset_mgiribbons synonym: "environmental stress response defective" NARROW [] synonym: "stress response defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000409 name: abnormal osmotic stress response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to osmotic stress (GO:0006970). 'response to osmotic stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.'" [FBC:DOS, GOC:jl] synonym: "osmotic stress response defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response [Term] id: FBcv:0000410 name: abnormal heat stress response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to heat (GO:0009408). 'response to heat' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.'" [FBC:DOS, GOC:lr] synonym: "heat stress response defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response is_a: FBcv:0000683 ! abnormal temperature response [Term] id: FBcv:0000411 name: abnormal visual behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in visual behavior (GO:0007632). 'visual behavior' is defined as: 'The behavior of an organism in response to a visual stimulus.'" [FBC:DOS, GOC:jid, GOC:pr] synonym: "visual behavior defective" EXACT [] synonym: "visual behaviour defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000412 name: abnormal optomotor response namespace: phenotypic_class def: "Phenotype that is any abnormality in optomotor response: a motor response during flight or walking that serves to stabilize both image formation on the retina and locomotor course." [FBC:DOS] synonym: "optomotor behaviour defective" EXACT [] synonym: "optomotor response defective" EXACT [] is_a: FBcv:0000411 ! abnormal visual behavior [Term] id: FBcv:0000413 name: abnormal phototaxis namespace: phenotypic_class def: "Phenotype that is any abnormality in phototaxis (GO:0042331). 'phototaxis' is defined as: 'The directed movement of a motile cell or organism in response to light.'" [FBC:DOS, GOC:jl, ISBN:0192800981] subset: fbcvsubset_mgiribbons synonym: "phototaxis behaviour defective" RELATED [] synonym: "phototaxis defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000414 name: abnormal locomotor behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in locomotory behavior (GO:0007626). 'locomotory behavior' is defined as: 'The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.'" [FBC:DOS, GOC:dph] synonym: "locomotor behavior defective" EXACT [] synonym: "locomotor behaviour defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000415 name: abnormal jumping namespace: phenotypic_class def: "Phenotype that is a reduced ability to jump or a reduced jump response. This may be due to neurological or muscular defects." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "jumping defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000416 name: uncoordinated namespace: phenotypic_class def: "Phenotype that is abnormal co-ordination of motor activity." [FBC:CP, FBC:DOS] is_a: FBcv:0000414 ! abnormal locomotor behavior [Term] id: FBcv:0000417 name: abnormal flight namespace: phenotypic_class def: "Phenotype that is any abnormality in flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'" [FBC:DOS, GOC:dph] comment: This term is agnostic as to the causes of defects in flight. An animal's flight may be defective for mechanical, behavioral or sensory reasons. subset: fbcvsubset_mgiribbons synonym: "flight behaviour defective" NARROW [] synonym: "flight defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000418 name: flightless namespace: phenotypic_class def: "Phenotype that is the absence of flight (GO:0060361). 'flight' is defined as: 'Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.'" [FBC:DOS, GOC:dph] comment: This term is agnostic as to the causes of flightlessness. An animal may be flightless for mechanical or behavioral reasons. is_a: FBcv:0000417 ! abnormal flight [Term] id: FBcv:0000419 name: abnormal feeding behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in feeding behavior (GO:0007631). 'feeding behavior' is defined as: 'Behavior associated with the intake of food.'" [FBC:DOS, GOC:mah] synonym: "feeding behavior defective" EXACT [] synonym: "feeding behaviour defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000420 name: abnormal grooming behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in grooming behavior (GO:0007625). 'grooming behavior' is defined as: 'The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.'" [FBC:DOS, GOC:jl, GOC:pr] synonym: "grooming behavior defective" EXACT [] synonym: "grooming behaviour defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000421 name: abnormal touch response namespace: phenotypic_class def: "Phenotype that is any abnormality in or loss of a stereotypical behavioral response to touch." [FlyBase:FBrf0073546] comment: This phenotype is commonly assayed by scoring larval avoidance responses following stroking of the thoracic segments (see Kernan et al., 1994). On its own, this is not sufficient evidence for an abnormality in sensory perception of touch, as motor defects can also cause this phenotype. synonym: "touch response defective" EXACT [] synonym: "touch sensitivity defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000422 name: photoperiod response variant namespace: phenotypic_class def: "Phenotype that is any abnormality in entrainment of circadian clock by photoperiod (GO:0043153), which is defined as: 'The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).'" [FBC:DOS, GOC:jl] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000423 name: abnormal DNA repair namespace: phenotypic_class def: "Phenotype that is any abnormality in DNA repair (GO:0006281). 'DNA repair' is defined as: 'The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.'" [FBC:DOS, PMID:11563486] synonym: "DNA repair defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response [Term] id: FBcv:0000424 name: abnormal cell death namespace: phenotypic_class def: "Phenotype that is a change in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type. This may be due to effects on the regulation of cell death (GO:0010941) or in cell death (GO:0008219) pathways themselves." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "apoptosis defective" NARROW [] synonym: "cell death defective" EXACT [] synonym: "pcd defective" NARROW [] synonym: "programmed cell death defective" NARROW [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000425 name: increased cell death namespace: phenotypic_class def: "Phenotype that is an increase in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] synonym: "pcd increase" NARROW [] synonym: "programmed cell death increase" NARROW [] is_a: FBcv:0000424 ! abnormal cell death [Term] id: FBcv:0000426 name: decreased cell death namespace: phenotypic_class def: "Phenotype that is a decrease in the amount of cell death in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] synonym: "pcd decrease" NARROW [] synonym: "programmed cell death decrease" NARROW [] is_a: FBcv:0000424 ! abnormal cell death [Term] id: FBcv:0000427 name: abnormal cell growth namespace: phenotypic_class def: "Phenotype that is any abnormality in cell growth (GO:0016049). 'cell growth' is defined as: 'The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.'" [FBC:DOS, GOC:ai] comment: Note that defects in cell size are not necessarily the result of defects in cell growth. A change in the rate of cell division in the absence of any change in cell growth rate can result in smaller or larger cells. subset: fbcvsubset_mgiribbons synonym: "cell growth defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000428 name: abnormal cell size namespace: phenotypic_class def: "Phenotype that is any abnormality in the size of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "cell size defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000429 name: abnormal cell shape namespace: phenotypic_class def: "Phenotype that is any abnormality in the shape (PATO:0000052) of some cell compared to wild-type." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "cell shape defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000430 name: abnormal cell polarity namespace: phenotypic_class def: "Phenotype that is any abnormality in the asymmetric distribution of components within a cell. For example an epithelial cell is 'cell polarity defective' if it lacks the normal asymmetric distribution of proteins or cell components such as junctions or villi along its apical-basal axis." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "cell polarity defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000431 name: abnormal meiotic cell cycle namespace: phenotypic_class def: "Phenotype that is any abnormality in meiotic cell cycle (GO:0051321). 'meiotic cell cycle' is defined as: 'Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.'" [FBC:DOS, GOC:ai] synonym: "meiotic" RELATED [] synonym: "meiotic cell cycle defective" EXACT [] is_a: FBcv:0000671 ! abnormal cell cycle [Term] id: FBcv:0000432 name: abnormal mitotic cell cycle namespace: phenotypic_class def: "Phenotype that is any abnormality in mitotic cell cycle (GO:0000278). 'mitotic cell cycle' is defined as: 'Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.'" [FBC:DOS, GOC:mah, ISBN:0815316194, Reactome:69278] synonym: "mitotic" RELATED [] synonym: "mitotic cell cycle defective" EXACT [] is_a: FBcv:0000671 ! abnormal cell cycle [Term] id: FBcv:0000433 name: abnormal cytokinesis namespace: phenotypic_class def: "Phenotype that is any abnormality in cytokinesis (GO:0000910). 'cytokinesis' is defined as: 'The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.'" [FBC:DOS, GOC:mtg_cell_cycle] synonym: "cytokinesis defective" EXACT [] is_a: FBcv:0000671 ! abnormal cell cycle [Term] id: FBcv:0000434 name: abnormal neurophysiology namespace: phenotypic_class def: "Phenotype that is any abnormality in the electrophysiological properties of some class of neurons, muscles or other anatomical structure of the nervous system. Examples of these phenotypes at the neuron class level include defects in spontaneous or evoked excitatory junction potential. Examples at a more gross anatomical level include abnormal retinal electrophysiology (e.g.- measured by an electroretinogram)." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "neurophysiology defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000435 name: abnormal neuroanatomy namespace: phenotypic_class def: "Phenotype that is any abnormality in the anatomy of the nervous system (FBbt:00005093). 'nervous system' is defined as: 'All the nerve centers and nerve fibers in the central, visceral and peripheral nervous systems.'" [FBC:DOS, FlyBase:FBrf0166419] subset: fbcvsubset_mgiribbons synonym: "neuroanatomy defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000436 name: abnormal sex-determination namespace: phenotypic_class def: "Phenotype that is any abnormality in sex determination (GO:0007530). 'sex determination' is defined as: 'Any process that establishes and transmits the specification of sexual status of an individual organism.'" [FBC:DOS, ISBN:0198506732] subset: fbcvsubset_mgiribbons synonym: "sex-determination defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000437 name: obsolete dosage compensation defective namespace: phenotypic_class comment: This term was obsoleted because it was felt that the evidence provided in papers is not enough to annotate with this term. mc161014 is_obsolete: true consider: FBcv:0000436 [Term] id: FBcv:0000438 name: electrophoretic variant namespace: phenotypic_class def: "Phenotype that is a difference in electrophoretic migration of a gene product compared to wild-type." [FBC:DOS] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000439 name: chemical resistant namespace: phenotypic_class def: "Phenotype that is a decreased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000440 name: chemical sensitive namespace: phenotypic_class def: "Phenotype that is an increased sensitivity (compared to wild-type) to the toxic effects of some specified chemical. The phrase 'toxic effects' here refers to reversible effects such as inebriation and sedation as well as sustained damage, developmental defects and death." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000441 name: radiation resistant namespace: phenotypic_class def: "Phenotype that is a decreased tendency for radiation exposure to cause toxic effects." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000442 name: radiation sensitive namespace: phenotypic_class def: "Phenotype that is an increased tendency for radiation exposure to cause toxic effects." [FBC:DOS] subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000443 name: Minute namespace: phenotypic_class def: "Dominant phenotype consisting of short slender bristles and delayed development. Homozygotes are cell lethal." [FlyBase:FBrf0066905] comment: The phenotype may be a general result of mutations in essential components of the protein synthesis pathway, as a number of Minutes encode ribosomal proteins. In an animal that is heterozygous for a Minute mutation, cells with two wild-type alleles of the affected gene have a growth advantage. Many developmental studies take advantage of this fact to give somatic clones a growth advantage. The term 'Minute' should not be used to annotate the resulting phenotypes. is_a: FBcv:0000450 ! abnormal developmental rate [Term] id: FBcv:0000444 name: hyperplasia namespace: phenotypic_class def: "Phenotype that is an increase in size of a tissue or organ due to increased numbers of cells, where the affected tissue or organ maintains its normal form." [ISBN:9780198506737] synonym: "hyperplastic" EXACT [] is_a: FBcv:0000362 ! increased cell number is_a: FBcv:0007507 ! increased size [Term] id: FBcv:0000445 name: obsolete tumorigenic namespace: phenotypic_class def: "Phenotype that is characterized by the formation of abnormal masses of tissue (tumors) as the result of neoplasia." [FBC:DOS] comment: Obsoleted as this is the same phenotype as neoplasia. is_obsolete: true replaced_by: FBcv:0000723 [Term] id: FBcv:0000446 name: melanotic mass phenotype namespace: phenotypic_class def: "Phenotype characterized by the formation of lumps of melanotic tissue inside the body in the absence of foreign bodies." [FlyBase:FBrf0094387, FlyBase:FBrf0194475] comment: Melanotic capsules are formed around foreign bodies in wild-type animals as part of the immune response, for example as a protection against parasitoid wasps. Some, but not all melanotic mass phenotypes involve ectopic activation of this immune response. While melanotic masses are commonly referred to as melanotic tumors in the historical literature, this is a misnomer as they are rarely neoplastic. synonym: "melanotic 'tumor'" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000447 name: melanotic necrosis namespace: phenotypic_class def: "Phenotype characterized by closely associated necrosis and melanization." [FlyBase:FBrf0155704] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000448 name: abnormal immune response namespace: phenotypic_class def: "Phenotype that is any abnormality in immune response (GO:0006955). 'immune response' is defined as: 'Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.'" [FBC:DOS, GO_REF:0000022, GOC:add] subset: fbcvsubset_mgiribbons synonym: "immune response defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000449 name: abnormal planar polarity namespace: phenotypic_class def: "Phenotype that is any abnormality in establishment of planar polarity (GO:0001736). 'establishment of planar polarity' is defined as: 'Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.'" [GOC:dph] comment: For apical-basal polarity phenotypes of epithelia, the appropriate term is 'cell polarity defective'. subset: fbcvsubset_mgiribbons synonym: "planar polarity defective" EXACT [] synonym: "tissue polarity defective" BROAD [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000450 name: abnormal developmental rate namespace: phenotypic_class def: "Phenotype that is a change in the rate of some developmental process (GO:0032502) taking place prior to mature adulthood (defined as adult stage A3), compared to wild-type. Note, developmental processes include stages in development of the whole animal (e.g.- larval development) as well as specific sub-processes, such as dorsal closure." [FBC:DOS] comment: A more complete formalization would require a clause specifying stage. It might be possible to do this in OWL using the same system as we are using for lethal phase. subset: fbcvsubset_mgiribbons synonym: "developmental rate defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000451 name: abnormal wound healing namespace: phenotypic_class def: "Phenotype that is any abnormality in wound healing (GO:0042060). 'wound healing' is defined as: 'The series of events that restore integrity to a damaged tissue, following an injury.'" [GOC:bf, PMID:15269788] synonym: "wound healing defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response [Term] id: FBcv:0000452 name: origin of mutation namespace: origin_of_mutation def: "Describes the origin of the mutation that causes a phenotype." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000807 ! allele descriptor [Term] id: FBcv:0000453 name: obsolete piggyBac ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000454 name: obsolete synthetic namespace: origin_of_mutation is_obsolete: true consider: FBcv:0000455 [Term] id: FBcv:0000455 name: in vitro construct namespace: origin_of_mutation def: "DNA change introduced by using an in vitro construct. The sequence of the in vitro construct determines the type of change." [FBC:MMC] synonym: "change induced by in vitro construct" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000456 name: in vitro construct - regulatory fusion namespace: origin_of_mutation def: "Sequence change introduced by using an in vitro construct that contains a fusion of the regulatory region of one gene on to the coding region of another. Examples in FlyBase include heat shock constructs, FRT flip out constructs and reporter genes." [FBC:DOS] comment: Notes on usage: Use this, rather than 'in vitro construct - deletion', for families of promoter deletions. Thus, a family of deletions of eve promoters driving Ecol\\\\lacZ will have regulatory fusion, but not deletion, as their mutagen. synonym: "change induced by an in vitro construct - regulatory fusion" EXACT [] synonym: "in vitro construct | regulatory fusion" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000457 name: in vitro construct - coding region fusion namespace: origin_of_mutation def: "Sequence change introduced by using an in vitro construct that contains a in-frame fusion of the open reading frames from two or more genes. In FlyBase, the resulting genes may be classified as fusion genes or tagged genes." [FBC:DOS] synonym: "change induced by an in vitro construct - coding region fusion" EXACT [] synonym: "in vitro construct | coding region fusion" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000458 name: in vitro construct - site directed mutagenesis namespace: origin_of_mutation def: "Mutation induced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene." [FBC:DOS] synonym: "in vitro construct | site directed mutagenesis" RELATED [] synonym: "mutation induced by an in vitro construct - site directed mutagenesis" EXACT [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000459 name: in vitro construct - deletion namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct generated by internal deletion of some genomic sequence or cDNA." [FBC:DOS] synonym: "change induced by an in vitro construct - deletion" EXACT [] synonym: "in vitro construct | deletion" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000460 name: in vitro construct - genomic fragment namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct containing a genomic fragment that partially or fully rescues loss of function mutations or deletions of the gene whose sequence it carries." [FBC:DOS] comment: Notes on usage: 1. This term is applicable whether or not rescue using the construct is complete. 2. When a smaller rescue fragment is derived from a larger, by deletion of one or both ends, the mutagen shall be 'in vitro construct | deletion', with the larger being stated as the progenitor allele. synonym: "change induced by an in vitro construct - genomic fragment" EXACT [] synonym: "in vitro construct | genomic fragment" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000461 name: in vitro construct - minigene namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct that contains the wild-type open reading frame of a gene (without introns), the expression of which is controlled by a wild-type promoter of the same gene. Such constructs are often generated by fusing a cDNA to a genomic region containing promoter sequences, or more rarely by deletion of introns and other non-essential sequences from a genomic region, leaving a wild type coding region and promoter intact." [FBC:DOS] synonym: "change induced by an in vitro construct - minigene" EXACT [] synonym: "in vitro construct | minigene" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000462 name: in vitro construct - amino acid replacement namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct that uses site directed mutagenesis to target a particular region of the gene resulting in a change to the change to the amino acids sequence encodes.." [FBC:DOS] synonym: "change induced by an in vitro construct - amino acid replacement" EXACT [] synonym: "in vitro construct | amino acid replacement" RELATED [] is_a: FBcv:0000458 ! in vitro construct - site directed mutagenesis [Term] id: FBcv:0000463 name: in vitro construct - RNAi namespace: origin_of_mutation def: "Sequence change introduced by an in vitro construct designed to generate dsRNA for RNA interference (RNAi) experiments." [FBC:DOS] synonym: "change induced by an in vitro construct - RNAi" EXACT [] synonym: "in vitro construct | RNAi" RELATED [] is_a: FBcv:0000455 ! in vitro construct [Term] id: FBcv:0000464 name: obsolete in vitro construct - other namespace: origin_of_mutation synonym: "in vitro construct | other" EXACT [] is_obsolete: true consider: FBcv:0000455 [Term] id: FBcv:0000465 name: natural population namespace: origin_of_mutation def: "Mutation found in a natural population." [FBC:MMC] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000466 name: temperature namespace: origin_of_mutation def: "Mutation caused by exposure to a temperature that is higher or lower than 25 degrees Celsius." [FBC:MMC] synonym: "environmental treatment" RELATED [] synonym: "mutation induced by temperature treatment" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000467 name: cold namespace: origin_of_mutation def: "Mutation induced by exposure to temperature that is lower than 25 degrees Celsius." [FBC:MMC] synonym: "cold-treatment" RELATED [] synonym: "mutation induced by cold treatment" EXACT [] is_a: FBcv:0000466 ! temperature [Term] id: FBcv:0000468 name: heat namespace: origin_of_mutation def: "Mutation induced by exposure to a temperature that is higher than 25 degrees Celsius." [FBC:MMC] synonym: "heat-treatment" RELATED [] synonym: "mutation induced by heat treatment" EXACT [] is_a: FBcv:0000466 ! temperature [Term] id: FBcv:0000469 name: spontaneous namespace: origin_of_mutation def: "Mutation caused by a spontaneous event." [FBC:MMC] synonym: "mutation induced by spontaneous event" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000470 name: recombination namespace: origin_of_mutation def: "Sequence change induced by the genetic exchange that takes place between DNA sequences." [FBC:MC, ISBN:978-0-8153-3218-3] synonym: "change induced by recombination" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000471 name: gene conversion namespace: origin_of_mutation def: "Sequence change caused by a DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor (GO:0035822)." [PMID:17846636] comment: Strictly, gene conversion (GO:0035822) defines only the endogenous process, not its use for engineered gene targeting. synonym: "change induced by gene conversion" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000472 name: intralocus exchange namespace: origin_of_mutation def: "Mutation caused by a recombination event that causes the unequal exchange of small intralocus regions, usually leading to the formation of duplication and deficiency products." [FBC:MC, FlyBase:FBrf0014117, FlyBase:FBrf0202435] synonym: "mutation induced by intralocus exchange" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000473 name: unequal recombination namespace: origin_of_mutation def: "Sequence change caused by a recombination event that causes an unequal exchange of genetic material between homologous or non-homologous regions." [FlyBase:FBrf0202435] synonym: "change induced by unequal recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000474 name: mitotic recombination namespace: origin_of_mutation def: "Sequence change caused by the exchange of genetic material during mitosis that occurs at crossing over, and more frequently between homologous chromosomes." [FlyBase:FBrf0202435] synonym: "change induced by mitotic recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000475 name: magnification namespace: origin_of_mutation def: "Sequence change caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and an increase in the number of functional copies. It causes a reversion from mutant to wild-type phenotype." [FlyBase:FBrf0202435, FlyBase:FBrf0218934] synonym: "mutation induced by magnification" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000476 name: detachment namespace: origin_of_mutation def: "Mutation that is caused by a recombination event that causes the breakdown of compound chromosome arms resulting in duplications or deletions in proximal regions." [FBC:MC, FlyBase:FBrf0202435] synonym: "mutation induced by detachment" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000477 name: reduction namespace: origin_of_mutation def: "Mutation caused by a recombination event between tandem repeats of rRNA genes that causes unequal chromatid exchange at crossing over and a reduction in the number of functional copies. It leads to an aggravation of phenotype, in the case of a mutation causing a change from a wildtype to mutant phenotype or a change from a mutant to a more severe mutant phenotype." [FlyBase:FBrf0026874] synonym: "mutation induced by reduction" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000478 name: site specific recombination namespace: origin_of_mutation def: "Sequence change induced by a recombination event catalyzed by a recombinase that occurs at specific nucleotide sequences." [FlyBase:FBrf0202435, ISBN:978-0-8153-3218-3] synonym: "change induced by site specific recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000479 name: FLPase namespace: origin_of_mutation def: "Sequence change caused by a site specific recombination event catalyzed by the tyrosine recombinase FLPase, that recognizes minimal FLP recombination target (FRT) sites of 34 base pairs. For site specific integration, the recombination site consists of 48 base pairs containing an additional isolated base pair and a third 13 base pair direct repeat." [FlyBase:FBrf0201927, UniProt:P03870] synonym: "change induced by FLPase recombination" EXACT [] is_a: FBcv:0000478 ! site specific recombination [Term] id: FBcv:0000480 name: I-SceI namespace: origin_of_mutation def: "Sequence change caused by the cleavage of an 18 base pair DNA sequence by the I-SceI endonuclease." [FlyBase:FBrf0128625, UniProt:P03882] synonym: "change induced by I-SceI endonuclease cleavage" EXACT [] synonym: "SCEI endonuclease" RELATED [] is_a: FBcv:0003007 ! site specific cleavage [Term] id: FBcv:0000481 name: cre recombinase namespace: origin_of_mutation def: "Sequence change induced by a site specific recombination event catalyzed by the tyrosine recombinase cre. Recombination is induced between two 34 base pairs loxP sites. These consist of two 13 base pair perfect inverted repeats flanking an 8 base pair asymmetric spacer that confers directionality." [FlyBase:FBrf0201927, PMID:6954485, UniProt:P06956] synonym: "change induced by cre recombinase recombination" EXACT [] synonym: "Cre recombinase" RELATED [] is_a: FBcv:0000478 ! site specific recombination [Term] id: FBcv:0000482 name: segregation namespace: origin_of_mutation def: "Sequence change induced by chromosomal segregation." [FBC:MMC] synonym: "change induced by segregation" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000483 name: transposable element activity namespace: origin_of_mutation def: "Mutation induced by the mobilization of a transposable element." [FBC:MC, FlyBase:FBrf0202435] synonym: "mutation induced by transposable element activity" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000484 name: IR-hybrid dysgenesis namespace: origin_of_mutation def: "Mutation caused by hybrid dysgenesis that results from the mobilization of the I-element retrotransposon." [FlyBase:FBrf0202435] synonym: "IR" RELATED [] synonym: "mutation induced by IR-hybrid dysgenesis" EXACT [] is_a: FBcv:0003019 ! I-element activity [Term] id: FBcv:0000485 name: Stalker-hybrid dysgenesis namespace: origin_of_mutation def: "Mutation induced by hybrid dysgenesis caused by the mobilization of the Stalker transposable element." [FlyBase:FBrf0202435] synonym: "mutation induced by Stalker-hybrid dysgenesis" EXACT [] is_a: FBcv:0003020 ! Stalker element activity [Term] id: FBcv:0000486 name: P-element activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by a P-element, a DNA transposable element. The P-element is 2.9 kilobases in length with 31 base pairs inverted terminal repeats. Upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion. Mobilization is induced by the activity of a P-element transposase." [FlyBase:FBrf0202435] synonym: "mutation induced by P-element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000487 name: PM hybrid dysgenesis namespace: origin_of_mutation def: "Mutation caused by hybrid dysgenesis that results from the action of the P-element." [FlyBase:FBrf0202435] synonym: "mutation induced by PM hybrid dysgenesis" EXACT [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000488 name: Delta2-3 transposase namespace: origin_of_mutation def: "Mutation induced by the mobilization of a P-element by the Delta2-3 transposase. The source of Delta2-3 is a stable genomic integration from which the third intron has been deleted." [FlyBase:FBrf0202435] synonym: "&Dgr;2-3" RELATED [] synonym: "mutation induced by P-element mobilization by Delta2-3 transposase" EXACT [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000489 name: jumpstarter activity namespace: origin_of_mutation def: "Mutation caused by a P-element that is inserted into the genome and that is used to create more insertions at other sites." [FlyBase:FBrf0202435] synonym: "Js" RELATED [] synonym: "Jumpstarter" RELATED [] synonym: "mutation induced by jumpstarter mobilization" EXACT [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000490 name: p pi25.1 supplied transposase namespace: origin_of_mutation def: "Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.1. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It is missing a 23 base pairs deletion of the 3' terminus compared to p pi25.1wc." [FlyBase:FBrf0202435] synonym: "mutation induced by P-element mobilization by p pi25.1 supplied transposase" EXACT [] synonym: "p pi25.1" RELATED [] synonym: "p&pgr;25.1" RELATED [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000491 name: p pi25.7wc namespace: origin_of_mutation def: "Mutation caused by the mobilization of a P-element by the transposase produced from the helper plasmid p pi25.7wc. This plasmid is a P-element from which the 3' terminus has been deleted, making it unable to integrate into the host's DNA. It has an additional 23 base pairs deletion of the 3' terminus compared to p pi25.1." [FlyBase:FBrf0202435] synonym: "mutation induced by P-element mobilization by p pi25.7wc supplied transposase" EXACT [] synonym: "p pi25.7wc" RELATED [] synonym: "p&pgr;25.7wc" RELATED [] is_a: FBcv:0000486 ! P-element activity [Term] id: FBcv:0000492 name: male recombination induced by dysgenesis namespace: origin_of_mutation def: "Mutation caused by PM hybrid dysgenesis that is induced by the higher frequency of recombination in certain male chromosomes." [FlyBase:FBrf0202435] synonym: "MR" RELATED [] synonym: "mutation induced by male recombination" EXACT [] is_a: FBcv:0000487 ! PM hybrid dysgenesis [Term] id: FBcv:0000493 name: MRh12 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event induced by a male recombination factor which is present in chromosomes extracted from a population in Haifa, Israel." [FlyBase:FBrf0202435] synonym: "MRh12" RELATED [] synonym: "mutation induced by MRh12 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000494 name: MRT007 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event in the second and third chromosomes induced by a male recombination factor which is present in chromosomes extracted from a population in Harlingen, Texas." [FlyBase:FBrf0202435] synonym: "MRT007" RELATED [] synonym: "mutation induced by MRT007 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000495 name: MRF23.5 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event induced by male recombination factor 23.5 MRF which is present in second chromosomes extracted from a population in Patras, Greece." [FlyBase:FBrf0039984, FlyBase:FBrf0202435] synonym: "23.5 MRF" EXACT [FlyBase:FBrf0039984] synonym: "MRF23.5" RELATED [] synonym: "mutation induced by MRF23.5 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000496 name: MRF31.1 induced male recombination namespace: origin_of_mutation def: "Mutation caused by a male recombination event induced by male recombination factor 31.1 MRF which is present in second chromosomes extracted from a population in Patras, Greece." [FlyBase:FBrf0030109, FlyBase:FBrf0202435] synonym: "31.1 MRF" EXACT [FlyBase:FBrf0030109] synonym: "MRF31.1" RELATED [] synonym: "mutation induced by MRF31.1 male recombination" EXACT [] is_a: FBcv:0000492 ! male recombination induced by dysgenesis [Term] id: FBcv:0000497 name: hobo activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by hobo, a DNA transposable element. The hobo element is 3.0 kilobases in length with 12 base pairs inverted terminal repeats. After mobilization by the hobo transposase and upon insertion it generates a flanking duplication of 8 base pairs at the target site upon insertion." [FlyBase:FBrf0202435] synonym: "mutation induced by hobo element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000498 name: hobo dysgenesis namespace: origin_of_mutation def: "Mutation caused by hybrid dysgenesis that results from the mobilization of the hobo element." [FlyBase:FBrf0202435] synonym: "mutation induced by hobo dysgenesis" EXACT [] is_a: FBcv:0000497 ! hobo activity [Term] id: FBcv:0000499 name: HBL1 supplied transposase namespace: origin_of_mutation def: "Mutation caused by the activity of the hobo element, mobilized by an hobo transposase which is produced from the supplied P-element helper plasmid HBL1." [FlyBase:FBrf0202435] synonym: "Hobbled1" RELATED [] synonym: "Hobo transposase source" RELATED [] synonym: "mutation induced by Hobo transposase source HBL1" EXACT [] is_a: FBcv:0000497 ! hobo activity [Term] id: FBcv:0000500 name: mariner activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by mariner, a DNA transposable element. The mariner element is 1.3 kilobases in length with 28 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of these two bases upon insertion. Mobilization is induced by the activity of the mariner transposase." [FlyBase:FBrf0202435] synonym: "mutation induced by mariner activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000501 name: gypsy element activity namespace: origin_of_mutation def: "Mutation induced by transposable activity caused by the gypsy retrovirus. The gypsy element is a 7.5 kilobases in length with 482 base pairs terminal repeats. Mobilization is induced by the activity of the gypsy element transposase." [FlyBase:FBrf0202435] synonym: "mutation induced by gypsy element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000502 name: piggyBac activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by piggyBac, a DNA transposable element. The piggyBac is 2.5 kilobases in length with 13 base pairs inverted terminal repeats. It specifically targets TTAA dinucleotides and generates a flanking duplication of these 4 base pairs upon insertion. Mobilization is induced by the activity of the piggyBac transposase." [FlyBase:FBrf0202435] synonym: "mutation induced by piggyBac activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0000503 name: irradiation namespace: origin_of_mutation def: "Mutation induced by exposure to radiation." [FBC:MMC] synonym: "mutation induced by irradiation" EXACT [] is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000504 name: ionizing radiation namespace: origin_of_mutation def: "Mutation induced by exposure to ionizing radiation." [FBC:MMC] synonym: "mutation induced by ionizing irradiation" EXACT [] is_a: FBcv:0000503 ! irradiation [Term] id: FBcv:0000505 name: alpha ray namespace: origin_of_mutation def: "Mutation induced by exposure to alpha rays." [FBC:MMC] synonym: "&agr; ray" RELATED [] synonym: "mutation induced by alpha ray irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000506 name: gamma ray namespace: origin_of_mutation def: "Mutation induced by exposure to gamma rays." [FBC:MMC] synonym: "&ggr; ray" RELATED [] synonym: "mutation induced by gamma ray irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000507 name: 60Co gamma ray namespace: origin_of_mutation def: "Mutation induced by exposure to 60Co gamma rays." [FBC:MMC] synonym: "60Co &ggr; ray" RELATED [] synonym: "mutation induced by 60Co gamma ray irradiation" EXACT [] is_a: FBcv:0000506 ! gamma ray [Term] id: FBcv:0000508 name: 137Cs gamma ray namespace: origin_of_mutation def: "Mutation induced by exposure to 137Cs gamma rays." [FBC:MMC] synonym: "137Cs &ggr; ray" RELATED [] synonym: "mutation induced by 137Cs gamma ray irradiation" EXACT [] is_a: FBcv:0000506 ! gamma ray [Term] id: FBcv:0000509 name: 226Ra alpha ray namespace: origin_of_mutation def: "Mutation induced by exposure to 226Ra alpha rays." [FBC:MMC] synonym: "226Ra &agr; ray" RELATED [] synonym: "mutation induced by 226Ra alpha ray irradiation" EXACT [] synonym: "radium" RELATED [] is_a: FBcv:0000505 ! alpha ray [Term] id: FBcv:0000510 name: 32P namespace: origin_of_mutation def: "The radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days." [CHEBI:37972] synonym: "32-phosphorous" EXACT [] synonym: "mutation induced by 32-P irradiation" EXACT [] synonym: "phosphorus-32 atom" EXACT [] is_a: CHEBI:28659 ! phosphorus atom is_a: CHEBI:37972 ! phosphorus-32 atom [Term] id: FBcv:0000511 name: 3H namespace: origin_of_mutation def: "The radioactive isotope of hydrogen with relative atomic mass 3.016049 and half-life of 12.33 years (from Greek taurhoiotatauomicronsigma, third)." [CHEBI:29238] synonym: "hydrogen-3" EXACT [] synonym: "mutation induced by 3H irradiation" EXACT [] synonym: "tritium atom" EXACT [] is_a: CHEBI:29238 ! tritium atom is_a: CHEBI:49637 ! hydrogen atom [Term] id: FBcv:0000512 name: 3H-deoxycytidine namespace: origin_of_mutation def: "Mutation induced by exposure to 3H-deoxycytidine radiation." [FBC:MMC] synonym: "mutation induced by 3H-deoxycytidine irradiation" EXACT [] synonym: "tritiated 2'-deoxycytidine" EXACT [] synonym: "tritiated deoxycytidine" EXACT [] is_a: CHEBI:139359 ! tritiated compound is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside [Term] id: FBcv:0000513 name: 3H-thymidine namespace: origin_of_mutation def: "Thymidine linked to the radioisotope tritium. Used to label DNA in the study of cellular and viral DNA synthesis." [CHEBI:53526] synonym: "mutation induced by 3H-thymidine irradiation" EXACT [] synonym: "tritiated thymidine" EXACT [] is_a: CHEBI:139359 ! tritiated compound is_a: CHEBI:19255 ! pyrimidine 2'-deoxyribonucleoside is_a: CHEBI:53526 ! tritiated thymidine [Term] id: FBcv:0000514 name: Bevatron namespace: origin_of_mutation def: "Mutation induced by treatment in a Bevatron." [FBC:MMC] synonym: "mutation induced by Bevatron irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000515 name: deuteron namespace: origin_of_mutation def: "Mutation induced by exposure to deuteron radiation." [FBC:MMC] synonym: "mutation induced by deuteron irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000516 name: neutron namespace: origin_of_mutation def: "Mutation induced by exposure to neutron radiation." [FBC:MMC] synonym: "mutation induced by neutron irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000517 name: 252Cf fission neutron namespace: origin_of_mutation def: "Mutation induced by exposure to 252Cf fission neutron radiation." [FBC:MMC] synonym: "mutation induced by 252Cf fission neutron irradiation" EXACT [] is_a: FBcv:0000516 ! neutron [Term] id: FBcv:0000518 name: X ray namespace: origin_of_mutation def: "Mutation induced by exposure to X rays." [FBC:MMC] synonym: "mutation induced by X ray irradiation" EXACT [] is_a: FBcv:0000504 ! ionizing radiation [Term] id: FBcv:0000519 name: non-ionizing radiation namespace: origin_of_mutation def: "Mutation induced by exposure to non-ionizing radiation." [FBC:MMC] synonym: "mutation induced by non-ionizing irradiation" EXACT [] is_a: FBcv:0000503 ! irradiation [Term] id: FBcv:0000520 name: magnetic field namespace: origin_of_mutation def: "Mutation induced by exposure to a magnetic field." [FBC:MMC] synonym: "mutation induced by magnetic field irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000521 name: radio waves namespace: origin_of_mutation def: "Mutation induced by exposure to radio waves." [FBC:MMC] synonym: "mutation induced by radio waves irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000522 name: stratosphere namespace: origin_of_mutation def: "Mutation induced by exposure to the stratosphere." [FBC:MMC] synonym: "mutation induced by stratosphere irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000523 name: supersonic namespace: origin_of_mutation def: "Mutation induced by exposure to supersonic radiation." [FBC:MMC] synonym: "mutation induced by supersonic irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000524 name: U.V. namespace: origin_of_mutation def: "Mutation induced by exposure to U.V. radiation." [FBC:MMC] synonym: "mutation induced by U.V. irradiation" EXACT [] is_a: FBcv:0000519 ! non-ionizing radiation [Term] id: FBcv:0000525 name: chemical namespace: origin_of_mutation def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." [CHEBI:24431] synonym: "mutation induced by chemical exposure" EXACT [] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000452 ! origin of mutation [Term] id: FBcv:0000526 name: alkylating agent namespace: origin_of_mutation def: "Any chemical (FBcv:0000525) that has role some alkylating agent (CHEBI:22333)." [CHEBI:22333] synonym: "mutation induced by alkylating agent exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical intersection_of: FBcv:0000525 ! chemical intersection_of: has_role CHEBI:22333 ! alkylating agent relationship: has_role CHEBI:22333 ! alkylating agent [Term] id: FBcv:0000527 name: diethyl sulfate namespace: origin_of_mutation def: "No description." [CHEBI:34699] synonym: "DES" RELATED [] synonym: "mutation induced by diethyl sulfate exposure" EXACT [] is_a: CHEBI:29281 ! alkyl sulfate is_a: CHEBI:34699 ! diethyl sulfate is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000528 name: 2-chloroethyl methanesulfonate namespace: origin_of_mutation def: "No description." [CHEBI:19508] synonym: "CB1506" RELATED [] synonym: "mutation induced by 2-chloroethyl methanesulfonate exposure" EXACT [] is_a: CHEBI:19508 ! 2-chloroethyl methanesulfonate is_a: CHEBI:25223 ! methanesulfonate ester is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000529 name: 2-fluoroethyl methanesulfonate namespace: origin_of_mutation def: "No description." [CHEBI:19579] synonym: "CB1522" RELATED [] synonym: "mutation induced by 2-fluoroethyl methanesulfonate exposure" EXACT [] is_a: CHEBI:19579 ! 2-fluoroethyl methanesulfonate is_a: CHEBI:25223 ! methanesulfonate ester is_a: CHEBI:37143 ! organofluorine compound is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000530 name: ethyl methanesulfonate namespace: origin_of_mutation def: "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol." [CHEBI:23994] synonym: "CB1528" RELATED [] synonym: "EMS" RELATED [] synonym: "mutation induced by EMS exposure" EXACT [] synonym: "mutation induced by ethyl methanesulfonate exposure" EXACT [] is_a: CHEBI:23994 ! ethyl methanesulfonate is_a: CHEBI:25223 ! methanesulfonate ester is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000531 name: ethyl nitrosourea namespace: origin_of_mutation def: "A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups." [CHEBI:23995] synonym: "ENU" RELATED [] synonym: "mutation induced by ENU exposure" EXACT [] synonym: "mutation induced by ethyl nitrosourea exposure" EXACT [] synonym: "N-ethyl-N-nitrosourea" RELATED [CHEBI:23995] is_a: CHEBI:23995 ! N-ethyl-N-nitrosourea is_a: CHEBI:76551 ! N-nitrosoureas is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000532 name: hycanthon methanesulfonate namespace: origin_of_mutation def: "A methanesulfonate salt resulting from the reaction of equimolar amounts of hycanthone and methanesulfonic acid. It was formerly used as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel." [CHEBI:24624] synonym: "HMS" RELATED [] synonym: "hycanthone mesylate" RELATED [CHEBI:24624] synonym: "mutation induced by HMS exposure" EXACT [] synonym: "mutation induced by hycanthon methanesulfonate exposure" EXACT [] is_a: CHEBI:24624 ! hycanthone mesylate is_a: CHEBI:38037 ! methanesulfonate salt is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000533 name: methyl methanesulfonate namespace: origin_of_mutation def: "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol." [CHEBI:25255] synonym: "CB1540" RELATED [] synonym: "MMS" RELATED [] synonym: "mutation induced by methyl methanesulfonate exposure" EXACT [] synonym: "mutation induced by MMS exposure" EXACT [] is_a: CHEBI:25223 ! methanesulfonate ester is_a: CHEBI:25255 ! methyl methanesulfonate is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000534 name: bis(2-chloroethyl) sulfide namespace: origin_of_mutation alt_id: FBcv:0000536 def: "An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention." [CHEBI:25434] synonym: "1,1'-thiobis(2-chloroethane)" RELATED [CHEBI:25434] synonym: "CB1735" RELATED [] synonym: "mustard gas" RELATED [CHEBI:25434] synonym: "mutation induced by bis(2-chloroethyl) sulfide exposure" EXACT [] synonym: "mutation induced by mustard gas exposure" EXACT [] synonym: "mutation induced by sulfur gas exposure" EXACT [] synonym: "sulfur mustard" RELATED [CHEBI:25434] is_a: CHEBI:23996 ! ethyl sulfide is_a: CHEBI:25434 ! bis(2-chloroethyl) sulfide is_a: CHEBI:36683 ! organochlorine compound is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000535 name: N-methyl-N'-nitro-N-nitrosoguanidine namespace: origin_of_mutation def: "An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position." [CHEBI:21759] synonym: "MNNG" RELATED [] synonym: "mutation induced by N-methyl-N'-nitro-N-nitrosoguanidine exposure" EXACT [] synonym: "NNG" RELATED [] is_a: CHEBI:21759 ! N-methyl-N'-nitro-N-nitrosoguanidine is_a: CHEBI:35800 ! nitroso compound is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000537 name: obsolete minos ammunition for transposable element mutagenesis is_obsolete: true [Term] id: FBcv:0000538 name: carbamate namespace: origin_of_mutation def: "No description." [CHEBI:13941] synonym: "mutation induced by carbamate exposure" EXACT [] is_a: CHEBI:13941 ! carbamate is_a: CHEBI:37022 ! amino-acid anion [Term] id: FBcv:0000539 name: urethane namespace: origin_of_mutation def: "A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages." [CHEBI:17967] synonym: "mutation induced by urethane exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:13941 ! carbamate is_a: CHEBI:17967 ! urethane is_a: CHEBI:23003 ! carbamate ester is_a: FBcv:0000538 ! carbamate [Term] id: FBcv:0000540 name: vinyl carbamate namespace: origin_of_mutation def: "No description." [CHEBI:27292] synonym: "mutation induced by vinyl carbamate exposure" EXACT [] is_a: CHEBI:13941 ! carbamate is_a: CHEBI:23003 ! carbamate ester is_a: CHEBI:27292 ! vinyl carbamate is_a: FBcv:0000538 ! carbamate [Term] id: FBcv:0000541 name: intercalating agent namespace: origin_of_mutation def: "Any chemical (FBcv:0000525) that has role some intercalator (CHEBI:24853)." [CHEBI:24853] synonym: "mutation induced by intercalating agent exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical intersection_of: FBcv:0000525 ! chemical intersection_of: has_role CHEBI:24853 ! intercalator relationship: has_role CHEBI:24853 ! intercalator [Term] id: FBcv:0000542 name: mitomycin C namespace: origin_of_mutation def: "No description." [CHEBI:27504] synonym: "mutation induced by mitomycin C exposure" EXACT [] is_a: CHEBI:25357 ! mitomycin is_a: CHEBI:27504 ! mitomycin C is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000543 name: quinacrine mustard namespace: origin_of_mutation def: "No description." [CHEBI:37595] comment: Mapped to CHEBI on basis of synonym - quinacrine mustard. Originally primary name, ICR 100 is now relegated to a synonym. synonym: "2-methoxy-6-[3-(ethyl-2-chloroethyl)aminopropylamino]acridine" RELATED [] synonym: "ICR 100" RELATED [CHEBI:37595] synonym: "mutation induced by quinacrine mustard exposure" EXACT [] is_a: CHEBI:37595 ! quinacrine mustard is_a: CHEBI:37598 ! nitrogen mustard is_a: CHEBI:51803 ! aminoacridines is_a: FBcv:0000541 ! intercalating agent is_a: FBcv:0000813 ! nitrogen mustard [Term] id: FBcv:0000544 name: ICR 170 namespace: origin_of_mutation def: "No description." [CHEBI:21183] synonym: "2-methoxy-6-dichloro-9-(3-ethyl-2-chloroethyl-aminopropylamino)acridine-dihydrochloride" RELATED [] synonym: "mutation induced by ICR 170 exposure" EXACT [] is_a: CHEBI:21183 ! ICR-170 is_a: CHEBI:22213 ! acridines is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000545 name: 1,2-dibromoethane namespace: origin_of_mutation def: "A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae." [CHEBI:28534] synonym: "DBE" RELATED [] synonym: "mutation induced by 1,2-dibromoethane exposure" EXACT [] is_a: CHEBI:22926 ! bromohydrocarbon is_a: CHEBI:22929 ! bromoalkane is_a: CHEBI:28534 ! 1,2-dibromoethane is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000546 name: 1,2-dichloroethane namespace: origin_of_mutation def: "A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2." [CHEBI:27789] synonym: "DCE" RELATED [] synonym: "mutation induced by 1,2-dichloroethane exposure" EXACT [] is_a: CHEBI:27789 ! 1,2-dichloroethane is_a: CHEBI:36016 ! chloroethanes is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000547 name: 1-bromo-2-chloroethane namespace: origin_of_mutation def: "A haloalkane that is bromoethane substituted by chlorine at position 2." [CHEBI:19032] synonym: "BCE" RELATED [] synonym: "mutation induced by 1-bromo-2-chloroethane exposure" EXACT [] is_a: CHEBI:19032 ! 1-bromo-2-chloroethane is_a: CHEBI:24469 ! haloalkane is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:37141 ! organobromine compound is_a: FBcv:0000541 ! intercalating agent [Term] id: FBcv:0000548 name: base analog namespace: origin_of_mutation def: "A molecule that can substitute for a normal nucleobase in nucleic acids." [CHEBI:67142] synonym: "nucleobase analogue" RELATED [CHEBI:67142] is_a: CHEBI:33832 ! organic cyclic compound is_a: CHEBI:67142 ! nucleobase analogue [Term] id: FBcv:0000549 name: 5-bromouracil namespace: origin_of_mutation def: "A pyrimidine having keto groups at the 2- and 4-positions and a bromo group at the 5-position. Used mainly as an experimental mutagen." [CHEBI:20552] synonym: "mutation induced by 5-bromouracil exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:20552 ! 5-bromouracil is_a: CHEBI:39447 ! pyrimidines is_a: CHEBI:67142 ! nucleobase analogue is_a: FBcv:0000548 ! base analog [Term] id: FBcv:0000550 name: 5-bromouridine namespace: origin_of_mutation def: "A uridine having a bromo substituent at the 5-position." [CHEBI:20553] synonym: "mutation induced by 5-bromouridine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:20553 ! 5-bromouridine is_a: CHEBI:27242 ! uridines is_a: CHEBI:67142 ! nucleobase analogue is_a: FBcv:0000548 ! base analog [Term] id: FBcv:0000551 name: enzyme inhibitor namespace: origin_of_mutation def: "Any chemical (FBcv:0000525) that has role some enzyme inhibitor (CHEBI:23924)." [CHEBI:23924] synonym: "mutation induced by enzyme inhibitor exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical intersection_of: FBcv:0000525 ! chemical intersection_of: has_role CHEBI:23924 ! enzyme inhibitor relationship: has_role CHEBI:23924 ! enzyme inhibitor [Term] id: FBcv:0000552 name: aminopterin namespace: origin_of_mutation def: "No description." [CHEBI:22526] synonym: "mutation induced by aminopterin exposure" EXACT [] is_a: CHEBI:22526 ! 4-aminofolic acid is_a: CHEBI:35692 ! dicarboxylic acid is_a: FBcv:0000551 ! enzyme inhibitor [Term] id: FBcv:0000553 name: inorganic compound namespace: origin_of_mutation def: "A molecular entity that contains no carbon." [CHEBI:24835] synonym: "inorganic molecular entity" EXACT [CHEBI:24835] synonym: "mutation induced by inorganic compound exposure" EXACT [] is_a: CHEBI:23367 ! molecular entity is_a: CHEBI:24835 ! inorganic molecular entity [Term] id: FBcv:0000554 name: cupric sulfate namespace: origin_of_mutation def: "A metal sulfate compound having copper(2+) as the metal ion." [CHEBI:23414] synonym: "copper(2+) sulfate" RELATED [CHEBI:23414] synonym: "mutation induced by cupric sulfate" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:23414 ! copper(II) sulfate is_a: CHEBI:51336 ! metal sulfate [Term] id: FBcv:0000555 name: H3BO3 namespace: origin_of_mutation def: "No description." [CHEBI:33118] synonym: "mutation induced by H3BO3 exposure" EXACT [] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:33118 ! boric acid is_a: CHEBI:59765 ! boric acids is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000556 name: sodium bisulphite namespace: origin_of_mutation def: "An inorganic sodium salt having hydrogensulfite as the counterion." [CHEBI:26709] synonym: "mutation induced by sodium bisulphite exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:26709 ! sodium hydrogensulfite is_a: CHEBI:38702 ! inorganic sodium salt is_a: CHEBI:48857 ! sulfite salt [Term] id: FBcv:0000557 name: sodium fluoride namespace: origin_of_mutation def: "A metal fluoride salt with a Na(+) counterion." [CHEBI:28741] synonym: "mutation induced by sodium fluoride exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24060 ! fluoride salt is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:28741 ! sodium fluoride is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000558 name: epoxy hydrocarbon namespace: origin_of_mutation def: "Mutation induced by exposure to epoxy hydrocarbon." [FBC:MMC] synonym: "mutation induced by epoxy hydrocarbon exposure" EXACT [] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000559 name: diepoxybutane namespace: origin_of_mutation def: "No description." [CHEBI:23704] synonym: "DEB" RELATED [] synonym: "erythritol anhydride" RELATED [] synonym: "mutation induced by diepoxybutane exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:23704 ! diepoxybutane is_a: CHEBI:32955 ! epoxide is_a: FBcv:0000558 ! epoxy hydrocarbon [Term] id: FBcv:0000560 name: diepoxyoctane namespace: origin_of_mutation def: "No description." [CHEBI:23705] synonym: "1,2:7,8-diepoxyoctane" RELATED [CHEBI:23705] synonym: "mutation induced by diepoxyoctane exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:23705 ! 1,2:7,8-diepoxyoctane is_a: CHEBI:32955 ! epoxide is_a: FBcv:0000558 ! epoxy hydrocarbon [Term] id: FBcv:0000561 name: obsolete unclassified chemical namespace: origin_of_mutation is_obsolete: true consider: FBcv:0000525 [Term] id: FBcv:0000562 name: 1,2:5,6-dibenzanthracene namespace: origin_of_mutation def: "No description." [CHEBI:35299] synonym: "mutation induced by 1,2:5,6-dibenzanthracene exposure" EXACT [] is_a: CHEBI:35296 ! ortho-fused polycyclic arene is_a: CHEBI:35299 ! dibenz[a,h]anthracene [Term] id: FBcv:0000563 name: 1,4-dimethanesulfonoxy-1,4-dimethylbutane namespace: origin_of_mutation def: "A methanesulfonate ester that is hexane-2,5-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups." [CHEBI:67107] synonym: "1,4-dimethanesulfonoxy-1:4-dimethylbutane" RELATED [] synonym: "CB2348" RELATED [] synonym: "dimethylmyleran" RELATED [CHEBI:67107] synonym: "mutation induced by 1,4-dimethanesulfonoxy-1,4-dimethylbutane exposure" EXACT [] is_a: CHEBI:25223 ! methanesulfonate ester is_a: CHEBI:67107 ! dimethylmyleran is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000564 name: 1,4-dimethanesulfonoxybut-2-yne namespace: origin_of_mutation def: "Mutation induced by exposure to 1,4-dimethanesulfonoxybut-2-yne." [FBC:MMC] synonym: "CB2058" RELATED [] synonym: "mutation induced by 1,4-dimethanesulfonoxybut-2-yne exposure" EXACT [] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000565 name: dominance relationship qualifier namespace: dominance_qualifier def: "Dominance relationships describe the dependence of the expression of a phenotypic attribute of an allele on the genotype at the locus in question. An allele might be recessive with respect to one phenotypic attribute, but dominant with respect to another." [FBC:rd] is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000566 name: 1,6-dimethylsulfonoxy D-mannitol namespace: origin_of_mutation def: "Mutation induced by exposure to 1,6-dimethylsulfonoxy D-mannitol." [FBC:MMC] synonym: "CB2511" RELATED [] synonym: "mutation induced by 1,6-dimethylsulfonoxy D-mannitol exposure" EXACT [] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000567 name: 1,6-dimethylsulfonoxy L-mannitol namespace: origin_of_mutation def: "Mutation induced by exposure to 1,6-dimethylsulfonoxy L-mannitol." [FBC:MMC] synonym: "CB2628" RELATED [] synonym: "mutation induced by 1,6-dimethylsulfonoxy L-mannitol exposure" EXACT [] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000568 name: 1-amino-2-naphthol-4-sulfonic acid namespace: origin_of_mutation def: "No description." [CHEBI:19024] synonym: "mutation induced by 1-amino-2-naphthol-4-sulfonic acid exposure" EXACT [] is_a: CHEBI:19024 ! 4-amino-3-hydroxynaphthalene-1-sulfonic acid is_a: CHEBI:36336 ! naphthalenesulfonic acid is_a: CHEBI:38034 ! aminonaphthalene [Term] id: FBcv:0000569 name: lucanthone namespace: origin_of_mutation def: "A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone." [CHEBI:51052] synonym: "1-diethylaminoethylethylamino-4-methyl-thioxanthenone" RELATED [] synonym: "1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one" RELATED [CHEBI:51052] synonym: "lucanthone" RELATED [CHEBI:51052] synonym: "mutation induced by lucanthone exposure" EXACT [] is_a: CHEBI:50930 ! thioxanthenes is_a: CHEBI:51052 ! lucanthone is_a: FBcv:0000551 ! enzyme inhibitor [Term] id: FBcv:0000570 name: 2-methoxyethanol namespace: origin_of_mutation def: "A hydroxyether that is ethanol substituted by a methoxy group at position 2." [CHEBI:46790] synonym: "mutation induced by 2-methoxyethanol exposure" EXACT [] is_a: CHEBI:172390 ! glycol ether is_a: CHEBI:46790 ! 2-methoxyethanol [Term] id: FBcv:0000571 name: 2,5-bis(ethyleneimino)-1,4-benzoquinone namespace: origin_of_mutation def: "A member of the class of 1,4-benzoquinones that is p-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups." [CHEBI:19363] synonym: "2,5,-bisethylene-imine-1,4-benzoquinone" RELATED [] synonym: "mutation induced by 2,5-bis(ethyleneimino)-1,4-benzoquinone exposure" EXACT [] is_a: CHEBI:132124 ! 1,4-benzoquinones is_a: CHEBI:19363 ! 2,5-bis(aziridin-1-yl)-1,4-benzoquinone is_a: CHEBI:22681 ! aziridines is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000572 name: 7-bromomethyl-12-methylbenz[a]anthracene namespace: origin_of_mutation def: "A member of the class of tetraphenes that is tetraphene in which the hydrogens at positions 7 and 12 are replaced by bromomethyl and methyl groups, respectively." [CHEBI:20787] synonym: "7-bromomethyl 12 methyl benz&agr; anthracine" RELATED [] synonym: "7-bromomethyl 12 methyl benzalpha anthracine" RELATED [] synonym: "7-bromomethyl-12-methyltetraphene" RELATED [CHEBI:20787] synonym: "mutation induced by 7-bromomethyl-12-methylbenz[a]anthracene exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:20787 ! 7-bromomethyl-12-methyltetraphene is_a: CHEBI:37141 ! organobromine compound is_a: CHEBI:51067 ! tetraphenes [Term] id: FBcv:0000573 name: actinomycin D namespace: origin_of_mutation def: "No description." [CHEBI:27666] synonym: "mutation induced by actinomycin D exposure" EXACT [] is_a: CHEBI:15369 ! actinomycin is_a: CHEBI:27666 ! actinomycin D [Term] id: FBcv:0000574 name: benzo(alpha)pyrene namespace: origin_of_mutation def: "An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings." [CHEBI:29865] synonym: "benzo(&agr;)pyrene" RELATED [] synonym: "benzo[a]pyrene" RELATED [CHEBI:29865] synonym: "mutation induced by benzo(alpha)pyrene exposure" EXACT [] is_a: CHEBI:29865 ! benzo[a]pyrene is_a: CHEBI:35300 ! ortho- and peri-fused polycyclic arene [Term] id: FBcv:0000575 name: caffeine namespace: origin_of_mutation def: "A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee." [CHEBI:27732] synonym: "mutation induced by caffeine exposure" EXACT [] is_a: CHEBI:27134 ! trimethylxanthine is_a: CHEBI:27732 ! caffeine is_a: FBcv:0000551 ! enzyme inhibitor [Term] id: FBcv:0000576 name: cisplatin namespace: origin_of_mutation def: "A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups)." [CHEBI:27899] synonym: "cis-dichlorodiammineplatinum(II)" RELATED [] synonym: "mutation induced by cisplatin exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:27899 ! cisplatin is_a: CHEBI:51214 ! diamminedichloroplatinum [Term] id: FBcv:0000577 name: colchicine namespace: origin_of_mutation def: "An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum." [CHEBI:23359] synonym: "mutation induced by colchicine exposure" EXACT [] is_a: CHEBI:22160 ! acetamides is_a: CHEBI:22315 ! alkaloid is_a: CHEBI:23359 ! colchicine is_a: CHEBI:35618 ! aromatic ether is_a: CHEBI:38032 ! carbotricyclic compound [Term] id: FBcv:0000578 name: dimethyl sulfoxide namespace: origin_of_mutation def: "A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents." [CHEBI:28262] synonym: "mutation induced by dimethyl sulfoxide exposure" EXACT [] is_a: CHEBI:134179 ! volatile organic compound is_a: CHEBI:22063 ! sulfoxide is_a: CHEBI:28262 ! dimethyl sulfoxide is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000579 name: DNA namespace: origin_of_mutation def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." [CHEBI:16991] synonym: "mutation induced by DNA treatment" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:16991 ! deoxyribonucleic acid is_a: CHEBI:33696 ! nucleic acid [Term] id: FBcv:0000580 name: ethyl ether namespace: origin_of_mutation def: "An ether in which the oxygen atom is linked to two ethyl groups." [CHEBI:35702] synonym: "mutation induced by ethyl ether exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:134179 ! volatile organic compound is_a: CHEBI:25698 ! ether is_a: CHEBI:35702 ! diethyl ether [Term] id: FBcv:0000581 name: ethylenimine namespace: origin_of_mutation def: "No description." [CHEBI:30969] synonym: "EI" RELATED [] synonym: "mutation induced by ethylenimine exposure" EXACT [] is_a: CHEBI:22681 ! aziridines is_a: CHEBI:30969 ! aziridine is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent is_a: CHEBI:37949 ! azacycloalkane is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000582 name: ethylene oxide namespace: origin_of_mutation def: "A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom." [CHEBI:27561] synonym: "ethylene oxide" RELATED [CHEBI:27561] synonym: "mutation induced by ethylene oxide exposure" EXACT [] synonym: "oxirane" RELATED [CHEBI:27561] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:27561 ! oxirane is_a: CHEBI:36389 ! saturated organic heteromonocyclic parent is_a: CHEBI:38104 ! oxacycle [Term] id: FBcv:0000583 name: fagaronine namespace: origin_of_mutation def: "No description." [CHEBI:28954] synonym: "mutation induced by fagaronine exposure" EXACT [] is_a: CHEBI:28954 ! fagaronine is_a: CHEBI:38517 ! benzophenanthridine alkaloid [Term] id: FBcv:0000584 name: formaldehyde namespace: origin_of_mutation def: "An aldehyde resulting from the formal oxidation of methanol." [CHEBI:16842] synonym: "mutation induced by formaldehyde exposure" EXACT [] is_a: CHEBI:16842 ! formaldehyde is_a: CHEBI:17478 ! aldehyde is_a: CHEBI:64708 ! one-carbon compound is_a: FBcv:0000551 ! enzyme inhibitor [Term] id: FBcv:0000585 name: hesperidine namespace: origin_of_mutation def: "A disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage." [CHEBI:28775] synonym: "hesperidin" RELATED [CHEBI:28775] synonym: "mutation induced by hesperidine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:140332 ! 4'-methoxyflavanones is_a: CHEBI:26587 ! rutinoside is_a: CHEBI:28775 ! hesperidin is_a: CHEBI:38738 ! monomethoxyflavanone is_a: CHEBI:38749 ! dihydroxyflavanone is_a: CHEBI:48024 ! 3'-hydroxyflavanones is_a: CHEBI:63353 ! disaccharide derivative is_a: CHEBI:72730 ! flavanone glycoside [Term] id: FBcv:0000586 name: hexamethylmelamine namespace: origin_of_mutation def: "No description." [CHEBI:24564] synonym: "altretamine" RELATED [] synonym: "HMM" RELATED [] synonym: "mutation induced by hexamethylmelamine exposure" EXACT [] synonym: "mutation induced by HMM exposure" EXACT [] is_a: CHEBI:24564 ! hexamethylmelamine is_a: CHEBI:38175 ! triamino-1,3,5-triazine [Term] id: FBcv:0000587 name: hexamethylphosphoramide namespace: origin_of_mutation def: "No description." [CHEBI:24565] synonym: "HMPA" RELATED [] synonym: "mutation induced by hexamethylphosphoramide exposure" EXACT [] synonym: "mutation induced by HMPA exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:17102 ! phosphoramide is_a: CHEBI:24565 ! hexamethylphosphoric triamide [Term] id: FBcv:0000588 name: iodine namespace: origin_of_mutation def: "Chemical element with atomic number 53." [CHEBI:24859] synonym: "mutation induced by iodine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:24473 ! halogen is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:24859 ! iodine atom is_a: FBcv:0000553 ! inorganic compound [Term] id: FBcv:0000589 name: Janus green B namespace: origin_of_mutation def: "No description." [CHEBI:21184] synonym: "Janus green B chloride" RELATED [CHEBI:21184] synonym: "mutation induced by Janus green B exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:21184 ! Janus Green B chloride is_a: CHEBI:36094 ! organic chloride salt [Term] id: FBcv:0000590 name: methoxy diethylnitrosamine namespace: origin_of_mutation def: "No description." [CHEBI:25234] comment: Mapped to CHEBI:25234 (1-methoxy-N-nitrosodiethylamine) based on synonym of nitrosodiethylamine being diethylnitrosamine and CHEBI:25234 being classified as a mutagen. synonym: "1-methoxy-N-nitrosodiethylamine" RELATED [CHEBI:25234] synonym: "mutation induced by methoxy diethylnitrosamine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25234 ! 1-methoxy-N-nitrosodiethylamine is_a: CHEBI:35803 ! nitrosamine [Term] id: FBcv:0000591 name: natural gas namespace: origin_of_mutation def: "Mutation induced by exposure to natural gas." [FBC:MMC] synonym: "mutation induced by natural gas exposure" EXACT [] is_a: CHEBI:24431 ! chemical entity is_a: FBcv:0000525 ! chemical [Term] id: FBcv:0000592 name: nitrosomethyl urea namespace: origin_of_mutation def: "A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups." [CHEBI:50102] synonym: "MNU" RELATED [] synonym: "mutation induced by MNU exposure" EXACT [] synonym: "mutation induced by nitrosomethyl urea exposure" EXACT [] synonym: "N-methyl-N-nitrosourea" RELATED [CHEBI:50102] is_a: CHEBI:50102 ! N-methyl-N-nitrosourea is_a: CHEBI:76551 ! N-nitrosoureas is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000593 name: N-nitrosodimethylamine namespace: origin_of_mutation def: "No description." [CHEBI:35807] synonym: "DMN" RELATED [] synonym: "mutation induced by DMN exposure" EXACT [] synonym: "mutation induced by N-nitrosodimethylamine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:35803 ! nitrosamine is_a: CHEBI:35807 ! N-nitrosodimethylamine [Term] id: FBcv:0000594 name: p-N,N-di(2-chloroethyl)aminophenylvaleric acid namespace: origin_of_mutation def: "No description." [CHEBI:25813] synonym: "CB1356" RELATED [] synonym: "mutation induced by p-N,N-di(2-chloroethyl)aminophenylvaleric acid exposure" EXACT [] is_a: CHEBI:25813 ! p-N,N-bis(2-chloroethyl)aminophenylvaleric acid is_a: CHEBI:33856 ! aromatic amino acid is_a: CHEBI:36683 ! organochlorine compound [Term] id: FBcv:0000595 name: p-N,N-di-(2-chloroethyl)amino-D-phenylalanine namespace: origin_of_mutation def: "No description." [CHEBI:25814] synonym: "CB3026" RELATED [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)amino-D-phenylalanine exposure" EXACT [] is_a: CHEBI:16733 ! D-alpha-amino acid is_a: CHEBI:25814 ! p-N,N-bis(2-chloroethyl)amino-D-phenylalanine is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:84143 ! D-phenylalanine derivative [Term] id: FBcv:0000596 name: p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine namespace: origin_of_mutation def: "A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring." [CHEBI:28876] synonym: "CB3007" RELATED [] synonym: "melphalan" RELATED [CHEBI:28876] synonym: "mutation induced by melphalan exposure" EXACT [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)amino-DL-phenylalanine exposure" EXACT [] is_a: CHEBI:28876 ! melphalan is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:37598 ! nitrogen mustard is_a: CHEBI:83822 ! non-proteinogenic L-alpha-amino acid is_a: CHEBI:84144 ! L-phenylalanine derivative is_a: FBcv:0000813 ! nitrogen mustard [Term] id: FBcv:0000597 name: p-N,N-di-(2-chloroethyl)amino-L-phenylalanine namespace: origin_of_mutation def: "No description." [CHEBI:25816] synonym: "CB3025" RELATED [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)amino-L-phenylalanine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25816 ! p-N,N-bis(2-chloroethyl)amino-L-phenylalanine is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:84144 ! L-phenylalanine derivative [Term] id: FBcv:0000598 name: obsolete dominant temperature-sensitive lethal balancer comment: Consider - FBsv:0001009. is_obsolete: true [Term] id: FBcv:0000599 name: p-N,N-di-(2-chloroethyl)aminophenylethylamine namespace: origin_of_mutation def: "No description." [CHEBI:25818] synonym: "CB3034" RELATED [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)aminophenylethylamine exposure" EXACT [] is_a: CHEBI:25818 ! 4-(2-aminoethyl)-N,N-bis(2-chloroethyl)aniline is_a: CHEBI:36683 ! organochlorine compound [Term] id: FBcv:0000600 name: p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine namespace: origin_of_mutation def: "No description." [CHEBI:25829] synonym: "CB305" RELATED [] synonym: "mutation induced by p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:25829 ! p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine is_a: CHEBI:36683 ! organochlorine compound [Term] id: FBcv:0000601 name: quinhydrone namespace: origin_of_mutation def: "No description." [CHEBI:26491] synonym: "mutation induced by quinhydrone exposure" EXACT [] is_a: CHEBI:26491 ! quinhydrone is_a: CHEBI:35504 ! addition compound [Term] id: FBcv:0000602 name: S-2-chloroethylcysteine namespace: origin_of_mutation def: "No description." [CHEBI:22025] synonym: "CB1592" RELATED [] synonym: "mutation induced by S-2-chloroethylcysteine exposure" EXACT [] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:22025 ! S-2-chloroethylcysteine is_a: CHEBI:23509 ! cysteine derivative is_a: CHEBI:36683 ! organochlorine compound [Term] id: FBcv:0000603 name: styryl quinoline namespace: origin_of_mutation def: "No description." [CHEBI:26800] synonym: "CB3086" RELATED [] synonym: "mutation induced by styryl quinoline exposure" EXACT [] is_a: CHEBI:26513 ! quinolines is_a: CHEBI:26800 ! styrylquinoline [Term] id: FBcv:0000604 name: triaziquone namespace: origin_of_mutation def: "A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which three of the ring hydrogens are replaced by aziridin-1-yl groups." [CHEBI:27090] synonym: "mutation induced by triaziquone exposure" EXACT [] is_a: CHEBI:132124 ! 1,4-benzoquinones is_a: CHEBI:22681 ! aziridines is_a: CHEBI:27090 ! triaziquone is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000605 name: triethylenemelamine namespace: origin_of_mutation def: "No description." [CHEBI:27919] synonym: "CB1246" RELATED [] synonym: "mutation induced by triethylenemelamine exposure" EXACT [] synonym: "TEM" RELATED [] synonym: "tretamine" RELATED [CHEBI:27919] is_a: CHEBI:26588 ! 1,3,5-triazines is_a: CHEBI:27919 ! tretamine is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000606 name: obsolete allele assay method namespace: mode_of_assay def: "Assay method used to generate an allele." [FBC:MMC] comment: This term has been obsoleted because it is no longer used and relevant. mc151005 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000607 name: obsolete In transgenic Drosophila namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000608 name: obsolete Whole-organism transient assay namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000609 name: obsolete Drosophila cell culture namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 xref: abbrev:3 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000610 name: obsolete In transgenic Drosophila (allele of one drosophilid species in genome of another drosophilid) namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 xref: abbrev:5 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000611 name: obsolete Whole-organism transient assay (allele from one drosophilid species assayed in another drosophilid) namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 xref: abbrev:6 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000612 name: obsolete In transgenic Drosophila (allele of foreign species in genome of drosophilid) namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 xref: abbrev:7 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000613 name: obsolete Whole-organism transient assay (allele of foreign species assayed in drosophilid) namespace: mode_of_assay comment: This term has been obsoleted because it is no longer used and relevant. mc151005 xref: abbrev:8 is_obsolete: true consider: FBcv:0000807 [Term] id: FBcv:0000614 name: obsolete stock descriptor comment: Consider - FBsv:0000000. is_obsolete: true [Term] id: FBcv:0000615 name: obsolete extracted wild-type chromosome is_obsolete: true [Term] id: FBcv:0000616 name: obsolete laboratory stock comment: I don't think this is a useful term. is_obsolete: true [Term] id: FBcv:0000617 name: obsolete selected wild-type stock is_obsolete: true [Term] id: FBcv:0000618 name: obsolete wild-type stock comment: Consider - FBsv:0001005. is_obsolete: true [Term] id: FBcv:0000619 name: obsolete isogenic stock comment: Consider - FBsv:0001002. is_obsolete: true [Term] id: FBcv:0000620 name: genetic interaction qualifier namespace: genetic_interaction_type def: "Qualifier that describes the relation between two phenotypes that are due to genotypes g1 and g2." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000621 name: suppressor namespace: genetic_interaction_type def: "The genotype g1 is a suppressor of genotype g2 if (and only if) the phenotype due to g2 is made less severe by g1." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Not used directly in curation, but automatically inferred from its inverse (suppressible). subset: do_not_manually_annotate is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000622 name: suppressible namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is suppressible by genotype g2 if the if the phenotype due to the genotype g1g2 is less severe than that due to g1 alone." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000623 name: enhancer namespace: genetic_interaction_type def: "Genotype g1 is enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Not used directly in curation, but automatically inferred from its inverse (enhanceable). subset: do_not_manually_annotate is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000624 name: enhanceable namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000625 name: non-enhancer namespace: genetic_interaction_type def: "Genotype g1 is a non-enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is not more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." [FBC:MMC, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Not used directly in curation, but automatically inferred from its inverse (non-enhanceable). subset: do_not_manually_annotate is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000626 name: non-enhanceable namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is non-enhanceable by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000627 name: non-suppressor namespace: genetic_interaction_type def: "The genotype g1 is a non-suppressor of genotype g2 if (and only if) the phenotype due to g2 is not made less severe by g1." [FBC:MMC, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] comment: Not used directly in curation, but automatically inferred from its inverse (non-suppressible). subset: do_not_manually_annotate is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000628 name: non-suppressible namespace: genetic_interaction_type def: "A phenotype due to genotype g1 is non-suppressible by genotype g2 if (and only if) the phenotype due to the genotype g1g2 is no less severe than the phenotype due to g1 alone." [FBC:DOS, FlyBase:FBrf0000957, ISBN:978-0-387-52054-4] is_a: FBcv:0000620 ! genetic interaction qualifier [Term] id: FBcv:0000629 name: obsolete dominant temperature-sensitive lethal balancer for chromosome 2 is_obsolete: true [Term] id: FBcv:0000630 name: obsolete dominant temperature-sensitive lethal balancer for chromosome 3 is_obsolete: true [Term] id: FBcv:0000631 name: obsolete DrosDel Project deficiency core kit stock is_obsolete: true [Term] id: FBcv:0000632 name: obsolete Bloomington Stock Center deficiency kit stock comment: Consider - FBsv:0000601. is_obsolete: true [Term] id: FBcv:0000633 name: obsolete Exelixis deficiency kit stock is_obsolete: true [Term] id: FBcv:0000634 name: obsolete duplication kit stock is_obsolete: true [Term] id: FBcv:0000635 name: obsolete Cambridge 2 duplication kit stock comment: Consider - FBsv:0000603. is_obsolete: true [Term] id: FBcv:0000636 name: obsolete Bloomington duplication kit stock comment: Consider - FBsv:0000602. is_obsolete: true [Term] id: FBcv:0000637 name: obsolete Gene Disruption Project stock is_obsolete: true [Term] id: FBcv:0000638 name: obsolete sequenced strain comment: Consider - FBsv:0001003. is_obsolete: true [Term] id: FBcv:0000639 name: obsolete Golic gene replacement kit stock comment: Consider - FBsv:0000604. is_obsolete: true [Term] id: FBcv:0000640 name: obsolete Golic laboratory gene replacement kit stock is_obsolete: true [Term] id: FBcv:0000641 name: obsolete stock by cytotype is_obsolete: true [Term] id: FBcv:0000642 name: obsolete H cytotype stock is_obsolete: true [Term] id: FBcv:0000643 name: obsolete hobo family transposable element insertions present is_obsolete: true [Term] id: FBcv:0000644 name: obsolete hobo family transposable element insertions absent is_obsolete: true [Term] id: FBcv:0000645 name: obsolete P cytotype stock is_obsolete: true [Term] id: FBcv:0000646 name: obsolete P-element family transposable element insertions absent is_obsolete: true [Term] id: FBcv:0000647 name: obsolete P-element family transposable element insertions present is_obsolete: true [Term] id: FBcv:0000648 name: obsolete mapping stock is_obsolete: true [Term] id: FBcv:0000649 name: obsolete visible allele recombination mapping stock is_obsolete: true [Term] id: FBcv:0000650 name: editorial namespace: pub_type def: "Work consisting of a statement of the opinions, beliefs, and policy of the editor or publisher of a journal, usually on current matters of medical or scientific significance to the medical community or society at large." [MeSH:D016421] xref: MeSH:D016421 is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000651 name: obsolete meeting report namespace: pub_type comment: This term was obsoleted to conform with the MeSH terms used by PubMed. Please use 'FBcv:0000199 is_obsolete: true replaced_by: FBcv:0000199 [Term] id: FBcv:0000652 name: compendium namespace: pub_type def: "A publication containing a collection of separate articles written by distinct authors." [FBC:SM] synonym: "multipub" EXACT [FBC:SM] synonym: "multipublication" EXACT [FBC:SM] synonym: "Parent publication" EXACT [FBC:SM] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000653 name: subset namespace: expression_qualifier def: "Restricted to unknown subtype(s) of a specified type." [FBC:DS] is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000654 name: embryonic pattern qualifier namespace: embryonic_pattern_qualifier def: "Qualifier that describes the expression pattern of an embryo." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000052 ! spatial qualifier [Term] id: FBcv:0000655 name: obsolete Vienna Drosophila RNAi Center comment: Consider - FBsv:0000107. synonym: "VDRC" EXACT [] synonym: "Vienna" EXACT [] is_obsolete: true [Term] id: FBcv:0000656 name: obsolete frozen specimen comment: Consider - FBsv:0000008. is_obsolete: true [Term] id: FBcv:0000657 name: obsolete mutant stock is_obsolete: true [Term] id: FBcv:0000658 name: obsolete DrosDel Project deficiency stock is_obsolete: true [Term] id: FBcv:0000659 name: obsolete deficiency stock is_obsolete: true [Term] id: FBcv:0000660 name: obsolete inbred line comment: Consider - FBsv:0000501. is_obsolete: true [Term] id: FBcv:0000661 name: obsolete isofemale line comment: Consider - FBsv:0000502. is_obsolete: true [Term] id: FBcv:0000662 name: obsolete recently collected stock def: "A stock established from flies collected in the wild within the past 3 years." [FBC:KM] comment: Consider - FBsv:0000504. is_obsolete: true [Term] id: FBcv:0000663 name: obsolete transposable element-containing stock is_obsolete: true [Term] id: FBcv:0000664 name: obsolete duplication stock is_obsolete: true [Term] id: FBcv:0000665 name: abnormal body size namespace: phenotypic_class def: "Phenotype that is an abnormality in body size compared to wild-type animals raised under the same conditions as the animals exhibiting the phenotype." [FBC:DOS] synonym: "body size defective" EXACT [] is_a: FBcv:0000354 ! visible is_a: FBcv:0000357 ! abnormal size [Term] id: FBcv:0000666 name: obsolete conference proceedings namespace: pub_type comment: This term was obsoleted to conform with the MeSH terms used by PubMed. Please use 'FBcv:0000199 is_obsolete: true replaced_by: FBcv:0000199 [Term] id: FBcv:0000667 name: website namespace: pub_type def: "A set of related web pages containing content such as text, images, video, audio, etc., prepared and maintained as a collection of information on a particular subject." [FBC:SM] is_a: FBcv:0000189 ! publication class [Term] id: FBcv:0000668 name: abnormal cell adhesion namespace: phenotypic_class def: "Phenotype that is any abnormality in cell adhesion (GO:0007155). 'cell adhesion' is defined as: 'The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.'" [FBC:DOS, GOC:hb, GOC:pf] subset: fbcvsubset_mgiribbons synonym: "cell adhesion defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000669 name: abnormal hatching behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in hatching behavior (GO:0035187). 'hatching behavior' is defined as: 'The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.'" [FBC:DOS, GOC:pr, PMID:10436051] synonym: "hatching behavior defective" EXACT [] synonym: "hatching behaviour defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior [Term] id: FBcv:0000670 name: abnormal eclosion namespace: phenotypic_class def: "Phenotype that is any abnormality in eclosion (GO:0007562). 'eclosion' is defined as: 'The emergence of an adult insect from a pupa case.'" [FBC:DOS, GOC:dgh, GOC:dos, GOC:mah, ISBN:0198600461] subset: fbcvsubset_mgiribbons synonym: "eclosion defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000671 name: abnormal cell cycle namespace: phenotypic_class def: "Phenotype that is any abnormality in cell cycle (GO:0007049). 'cell cycle' is defined as: 'The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.'" [FBC:DOS, GOC:go_curators, GOC:mtg_cell_cycle] subset: fbcvsubset_mgiribbons synonym: "cell cycle defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000672 name: abnormal endomitotic cell cycle namespace: phenotypic_class def: "Phenotype that is any abnormality in endomitotic cell cycle (GO:0007113). 'endomitotic cell cycle' is defined as: 'A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.'" [FBC:DOS, GOC:curators, GOC:dos, GOC:expert_vm] synonym: "endocycle defective" EXACT [] synonym: "endomitotic cell cycle defective" EXACT [] is_a: FBcv:0000432 ! abnormal mitotic cell cycle [Term] id: FBcv:0000673 name: obsolete sequenced whole genome stock comment: Consider - FBsv:0001003. is_obsolete: true [Term] id: FBcv:0000674 name: obsolete phiC31 based integration system is_obsolete: true [Term] id: FBcv:0000675 name: obsolete phiC31 docking site stock is_obsolete: true [Term] id: FBcv:0000676 name: obsolete multi-female collection comment: Consider - FBsv:0000503. is_obsolete: true [Term] id: FBcv:0000677 name: 60-70% egg length namespace: spatial_qualifier def: "60-70% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length created_by: djs93 creation_date: 2009-05-28T03:54:39Z [Term] id: FBcv:0000678 name: 80-100% egg length namespace: spatial_qualifier def: "80-100% of egg length from the posterior tip (0%) of the egg or pre-gastrula embryo." [FBC:DOS] is_a: FBcv:0000074 ! egg length created_by: djs93 creation_date: 2009-05-28T03:55:30Z [Term] id: FBcv:0000679 name: abnormal circadian behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in circadian behavior (GO:0048512). 'circadian behavior' is defined as: 'The specific behavior of an organism that recurs with a regularity of approximately 24 hours.'" [FBC:DOS, GOC:bf, GOC:go_curators, GOC:pr] synonym: "circadian behavior defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior is_a: FBcv:0000394 ! abnormal circadian rhythm created_by: djs93 creation_date: 2009-11-30T11:06:35Z [Term] id: FBcv:0000680 name: abnormal proboscis extension reflex namespace: phenotypic_class def: "Phenotype that is any abnormality in proboscis extension reflex (GO:0007637). 'proboscis extension reflex' is defined as: 'The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.'" [FB:FBrf0044924, FBC:DOS, GOC:jid] synonym: "proboscis extension reflex defective" EXACT [] is_a: FBcv:0000403 ! abnormal chemosensitive behavior [Term] id: FBcv:0000681 name: abnormal sensory perception namespace: phenotypic_class def: "Phenotype that is any abnormality in sensory perception (GO:0007600). 'sensory perception' is defined as: 'The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.'" [FBC:DOS, GOC:ai, GOC:dph] subset: fbcvsubset_mgiribbons synonym: "sensory perception defective" EXACT [] is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-02-23T12:28:26Z [Term] id: FBcv:0000682 name: abnormal touch perception namespace: phenotypic_class def: "Phenotype that is any abnormality in sensory perception of touch (GO:0050975). 'sensory perception of touch' is defined as: 'The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).'" [FBC:DOS, GOC:ai] synonym: "touch perception defective" EXACT [] is_a: FBcv:0000681 ! abnormal sensory perception [Term] id: FBcv:0000683 name: abnormal temperature response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to temperature stimulus (GO:0009266). 'response to temperature stimulus' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.'" [FBC:DOS, GOC:hb] subset: fbcvsubset_mgiribbons synonym: "temperature response defective" EXACT [] is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-02-23T12:51:02Z [Term] id: FBcv:0000684 name: abnormal cold stress response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to cold (GO:0009409). 'response to cold' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.'" [FBC:DOS, GOC:lr] synonym: "cold stress response defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response is_a: FBcv:0000683 ! abnormal temperature response created_by: djs93 creation_date: 2010-02-23T02:11:27Z [Term] id: FBcv:0000685 name: parental effect namespace: genotype_to_phenotype_relation def: "Parental effects describe the dependence of the expression of a phenotypic attribute of an allele on the parent from which that allele is inherited." [FBC:rd] is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000686 name: abnormal axis specification namespace: phenotypic_class def: "Phenotype that is any abnormality in axis specification (GO:0009798). 'axis specification' is defined as: 'The establishment, maintenance and elaboration of a pattern along a line or around a point.'" [FBC:DOS, GOC:dph, GOC:go_curators, GOC:isa_complete] comment: This phenotypic class does not encompass planar polarity. subset: fbcvsubset_mgiribbons synonym: "axis specification defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000687 name: balancer descriptor def: "Descriptor that relates to aspects of a balancer." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000013 ! descriptor [Term] id: FBcv:0000688 name: amorphic allele namespace: allele_class def: "An allele that completely lacks function, coding either for a completely inactive gene product or none at all." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] synonym: "amorph" RELATED [] synonym: "null" RELATED [] is_a: FBcv:0000287 ! loss of function allele created_by: djs93 creation_date: 2010-09-06T03:57:21Z [Term] id: FBcv:0000689 name: amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function, producing either a completely inactive gene product or none at all." [FlyBase:FBrf0049147] synonym: "molecular null" EXACT [] is_a: FBcv:0000688 ! amorphic allele created_by: djs93 creation_date: 2010-09-06T03:57:49Z [Term] id: FBcv:0000690 name: hypomorphic allele namespace: allele_class def: "Allele that makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] synonym: "hypomorph" EXACT [] is_a: FBcv:0000287 ! loss of function allele created_by: djs93 creation_date: 2010-09-06T03:58:15Z [Term] id: FBcv:0000691 name: hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FlyBase:FBrf0049147] is_a: FBcv:0000690 ! hypomorphic allele created_by: djs93 creation_date: 2010-09-06T03:59:31Z [Term] id: FBcv:0000692 name: neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern compared to wild-type." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000697 ! neomorphic allele created_by: djs93 creation_date: 2010-09-06T04:01:04Z [Term] id: FBcv:0000693 name: hypermorphic allele - molecular evidence namespace: allele_class def: "Allele shown by molecular evidence to make either a functionally wild-type gene product at increased levels or a gene product with the same function as wild-type but with increased activity." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000696 ! hypermorphic allele created_by: djs93 creation_date: 2010-09-06T04:01:04Z [Term] id: FBcv:0000694 name: antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product." [FlyBase:FBrf0049147] synonym: "dominant negative" RELATED [] is_a: FBcv:0000695 ! antimorphic allele created_by: djs93 creation_date: 2010-09-06T04:01:04Z [Term] id: FBcv:0000695 name: antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] synonym: "antimorph" RELATED [] is_a: FBcv:0000290 ! gain of function allele created_by: djs93 creation_date: 2010-09-06T04:02:05Z [Term] id: FBcv:0000696 name: hypermorphic allele namespace: allele_class def: "An allele that makes either increased amounts of a normal gene product or a gene product with normal function but increased activity compared to wild-type." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] synonym: "hypermorph" RELATED [] is_a: FBcv:0000290 ! gain of function allele created_by: djs93 creation_date: 2010-09-06T04:02:45Z [Term] id: FBcv:0000697 name: neomorphic allele namespace: allele_class def: "An allele that makes a gene product with a novel function or expression pattern compared to wild-type." [FlyBase:FBrf0002371, FlyBase:FBrf0049147] synonym: "neomorph" RELATED [] is_a: FBcv:0000290 ! gain of function allele created_by: djs93 creation_date: 2010-09-06T04:03:33Z [Term] id: FBcv:0000698 name: embryonic/larval segmentation phenotype namespace: phenotypic_class def: "A phenotype that is a disruption in the wild-type pattern of segments or parasegments of the embryo or larva." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. subset: fbcvsubset_mgiribbons is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000699 name: pair rule phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of alternate segments or parasegments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype [Term] id: FBcv:0000700 name: even pair-rule phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of even segments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. is_a: FBcv:0000699 ! pair rule phenotype [Term] id: FBcv:0000701 name: odd pair-rule phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of odd segments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. is_a: FBcv:0000699 ! pair rule phenotype [Term] id: FBcv:0000702 name: segment polarity phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype in which some fraction of each segment (along the anterior-posterior axis) is deleted and replaced by a mirror image duplication of the remaining part of the segment." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype [Term] id: FBcv:0000703 name: gap phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete loss of a contiguous stretch of 2 or more segments." [FlyBase:FBrf0035438] comment: Commonly assayed on the basis of phenotypic effects on segmentally repeated cuticular patterns. is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype [Term] id: FBcv:0000704 name: chemical conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence or absence of some specific chemical whose presence or absence does not induce the same defect in wild-type animals." [FBC:DOS] is_a: FBcv:0000309 ! conditional created_by: djs93 creation_date: 2010-09-20T11:13:19Z [Term] id: FBcv:0000705 name: abnormal sleep namespace: phenotypic_class def: "Phenotype that is any abnormality in sleep (GO:0030431). 'sleep' is defined as: 'Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.'" [FBC:DOS, ISBN:0192800981] subset: fbcvsubset_mgiribbons synonym: "sleep defective" EXACT [] is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-09-20T12:06:13Z [Term] id: FBcv:0000706 name: abnormal diapause namespace: phenotypic_class def: "Phenotype that is any abnormality in entry into diapause (GO:0055115). 'entry into diapause' is defined as: 'The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.'" [FBC:DOS, GOC:ds, GOC:jid, GOC:mah] synonym: "diapause defective" EXACT [] is_a: FBcv:0001347 ! phenotype created_by: djs93 creation_date: 2010-09-20T12:06:28Z [Term] id: FBcv:0000707 name: abnormal reproductive diapause namespace: phenotypic_class def: "Phenotype that is any abnormality in entry into reproductive diapause (GO:0055116). 'entry into reproductive diapause' is defined as: 'The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.'" [FBC:DOS, GOC:ds, GOC:jid, GOC:mah] synonym: "reproductive diapause defective" EXACT [] is_a: FBcv:0000706 ! abnormal diapause created_by: djs93 creation_date: 2010-09-20T12:21:29Z [Term] id: FBcv:0000708 name: abnormal starvation stress response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to starvation (GO:0042594). 'response to starvation' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.'" [FBC:DOS, GOC:go_curators] synonym: "starvation stress response defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response [Term] id: FBcv:0000709 name: abnormal cell number namespace: phenotypic_class def: "Phenotype that is an increase or decrease in the number of cells in a whole animal or in some specific organ, tissue or clone of cells compared to wild-type. This phenotype is not necessarily accompanied by defects in cell growth - there may be a greater or lesser number of cells in an otherwise normal volume of tissue." [FBC:DOS] subset: fbcvsubset_mgiribbons synonym: "cell number defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000710 name: gene targeting by homologous recombination namespace: origin_of_mutation def: "Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double stranded break in an engineered donor construct that contains sequence homologous to the target gene." [FBC:MC, FlyBase:FBrf0202435] comment: Strictly, homologous recombinational repair (GO:0000724) defines only the endogenous process, not its use for engineered gene targeting. synonym: "change induced by gene targeting via homologous recombination" EXACT [] is_a: FBcv:0000470 ! recombination [Term] id: FBcv:0000711 name: ends-out gene targeting namespace: origin_of_mutation def: "Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break on both sides of the homologous region in an engineered donor sequence. This double-strand break is usually generated by cutting at a single site adjacent to the homologous region in a circularized donor sequence. This typically generates a simple targeted replacement of the target sequence by the donor sequence. However, more complicated outcomes are possible." [FBC:MC, FlyBase:FBrf0167363, FlyBase:FBrf0202435] synonym: "change induced by ends-out gene targeting" EXACT [] is_a: FBcv:0000710 ! gene targeting by homologous recombination [Term] id: FBcv:0000712 name: ends-in gene targeting namespace: origin_of_mutation def: "Change of a genomic sequence via homologous recombinational repair (GO:0000724) that is induced by a double strand break within an engineered homologous donor sequence. This typically generates a tandem duplication of the homologous sequence from the donor, separated by the remainder of the incoming donor DNA. However, more complicated outcomes are possible." [FBC:MC, FlyBase:FBrf0167363, FlyBase:FBrf0202435] synonym: "change induced by ends-in gene targeting" EXACT [] is_a: FBcv:0000710 ! gene targeting by homologous recombination [Term] id: FBcv:0000713 name: jumpless namespace: phenotypic_class def: "Phenotype that is a inability to jump. This may be due to neurological or muscular defects." [FBC:DOS] is_a: FBcv:0000415 ! abnormal jumping created_by: djs93 creation_date: 2011-03-10T04:57:06Z [Term] id: FBcv:0000714 name: nutrition conditional namespace: environmental_qualifier def: "Phenotype only expressed under some specific nutritional regime." [FBC:DOS] is_a: FBcv:0000309 ! conditional created_by: djs93 creation_date: 2011-01-14T12:34:01Z [Term] id: FBcv:0000715 name: calorie restriction conditional namespace: environmental_qualifier def: "Phenotype only expressed under conditions where calorie intake is restricted." [FBC:DOS] is_a: FBcv:0000714 ! nutrition conditional created_by: djs93 creation_date: 2011-01-14T05:12:37Z [Term] id: FBcv:0000716 name: abnormal cell migration namespace: phenotypic_class def: "Phenotype that is any abnormality in cell migration (GO:0016477). 'cell migration' is defined as: 'The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.'" [FBC:DOS, GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] subset: fbcvsubset_mgiribbons synonym: "cell migration defective" EXACT [] is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0000717 name: increased cell growth namespace: phenotypic_class def: "Phenotype that is an increase in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] is_a: FBcv:0000427 ! abnormal cell growth [Term] id: FBcv:0000718 name: decreased cell growth namespace: phenotypic_class def: "Phenotype that is an decrease in the rate of cell growth (GO:0016049) in a whole animal or in some specific organ tissue or clone of cells compared to wild-type." [FBC:DOS] is_a: FBcv:0000427 ! abnormal cell growth [Term] id: FBcv:0000719 name: atrophy namespace: phenotypic_class def: "Phenotype that is a decrease in size of an initially normally sized organ or tissue due to wasting away of cells." [FBC:DOS] is_a: FBcv:0007508 ! decreased size created_by: djs93 creation_date: 2011-03-10T05:59:04Z [Term] id: FBcv:0000720 name: abnormal jump response namespace: phenotypic_class def: "Phenotype that is any abnormality or in or absence of a jump response (GO:0007630). The jump response in Drosophila is a reflex escape response that can be triggered by a number of signals including odor and light. Standard assays are commonly used to test odor and light induced jump response." [FlyBase:FBrf0187887, FlyBase:FBrf0191819] synonym: "jump response defective" EXACT [] is_a: FBcv:0000414 ! abnormal locomotor behavior is_a: FBcv:0000415 ! abnormal jumping created_by: djs93 creation_date: 2011-03-11T08:03:28Z [Term] id: FBcv:0000721 name: abnormal mating behavior namespace: phenotypic_class def: "Phenotype that is any abnormality in mating behavior (GO:0007617). 'mating behavior' is defined as: 'The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.'" [FBC:DOS, GOC:ai, GOC:dph] synonym: "mating behavior defective" EXACT [] is_a: FBcv:0000387 ! abnormal behavior is_a: FBcv:0000400 ! abnormal mating [Term] id: FBcv:0000722 name: somatic clone - Minute background namespace: clone_qualifier def: "A clone of somatic cells that share a mutant genotype that includes being Minute +/+ and that is part of and derived from an animal with a different genotype that includes being Minute +/-." [FBC:DOS] is_a: FBcv:0000336 ! somatic clone created_by: djs93 creation_date: 2011-01-27T04:55:28Z [Term] id: FBcv:0000723 name: neoplasia namespace: phenotypic_class def: "Phenotype that consists of abnormal growth of a tissue or organ due to increased numbers of cells, but in which the affected tissue or organ does not maintain its normal form." [FBC:DOS] synonym: "neoplasm" NARROW [] synonym: "neoplastic" NARROW [] synonym: "tumorigenesis" NARROW [] synonym: "tumorigenic" NARROW [] is_a: FBcv:0000357 ! abnormal size is_a: FBcv:0000362 ! increased cell number [Term] id: FBcv:0000724 name: hypoplasia namespace: phenotypic_class def: "Phenotype that is a reduction in size of an organ or tissue compared to wild-type due to reduced numbers of cells being produced during its development or growth." [FBC:DOS] comment: This term should not be used where an organ or tissue is reduced in size due to the wasting away of existing cells. is_a: FBcv:0000359 ! decreased cell number is_a: FBcv:0007508 ! decreased size [Term] id: FBcv:0000725 name: abnormal oxidative stress response namespace: phenotypic_class def: "Phenotype that is any abnormality in response to oxidative stress (GO:0006979). 'response to oxidative stress' is defined as: 'Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.'" [FBC:DOS, GOC:jl, PMID:12115731] synonym: "oxidative stress response defective" EXACT [] is_a: FBcv:0000408 ! abnormal stress response [Term] id: FBcv:0000726 name: virgin female namespace: sex_qualifier def: "Expressed in virgin females." [FBC:DOS] comment: May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in virgin females. is_a: FBcv:0000334 ! female created_by: djs93 creation_date: 2011-04-21T01:10:32Z [Term] id: FBcv:0000727 name: mated female namespace: sex_qualifier def: "Expressed in mated females." [FBC:DOS] comment: May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in mated females. is_a: FBcv:0000334 ! female created_by: djs93 creation_date: 2011-04-21T01:10:49Z [Term] id: FBcv:0000728 name: virgin male namespace: sex_qualifier def: "Expressed in virgin males." [FBC:DOS] comment: May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in virgin males. is_a: FBcv:0000333 ! male created_by: djs93 creation_date: 2011-04-21T01:11:13Z [Term] id: FBcv:0000729 name: mated male namespace: sex_qualifier def: "Expressed in mated males." [FBC:DOS] comment: May be used as a qualifier for gene or transgene expression or phenotype. Note - its use does not imply expression (of gene or phenotype) exclusively in mated females. is_a: FBcv:0000333 ! male created_by: djs93 creation_date: 2011-04-21T01:11:21Z [Term] id: FBcv:0000730 name: virgin female limited namespace: sex_qualifier def: "Expression is limited to virgin females." [FBC:DOS] comment: May be used to qualify expression of phenotypes or of genes, transgenes etc. is_a: FBcv:0000308 ! female limited created_by: djs93 creation_date: 2011-04-21T01:11:46Z [Term] id: FBcv:0000731 name: mated female limited namespace: sex_qualifier def: "Expression is limited to mated females." [FBC:DOS] comment: May be used to qualify expression of phenotypes or of genes, transgenes etc. is_a: FBcv:0000308 ! female limited created_by: djs93 creation_date: 2011-04-21T01:11:59Z [Term] id: FBcv:0000732 name: mated male limited namespace: sex_qualifier def: "Expression is limited to mated males." [FBC:DOS] comment: May be used to qualify expression of phenotypes or of genes, transgenes etc. is_a: FBcv:0000307 ! male limited created_by: djs93 creation_date: 2011-04-21T01:12:14Z [Term] id: FBcv:0000733 name: virgin male limited namespace: sex_qualifier def: "Expression is limited to virgin males." [FBC:DOS] comment: May be used to qualify expression of phenotypes or of genes, transgenes etc. is_a: FBcv:0000307 ! male limited created_by: djs93 creation_date: 2011-04-21T01:13:00Z [Term] id: FBcv:0000734 name: terminal phenotype namespace: phenotypic_class def: "Embryonic/larval segmentation phenotype that is the complete or partial loss of terminal regions of the embryo/larva: the acron, telson and immediately adjacent segments." [FBC:DOS] is_a: FBcv:0000698 ! embryonic/larval segmentation phenotype created_by: djs93 creation_date: 2011-09-13T02:31:53Z [Term] id: FBcv:0000735 name: N-nitrosodiethylamine namespace: origin_of_mutation def: "A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom." [CHEBI:34873] synonym: "mutation induced by N-nitrosodiethylamine exposure" EXACT [] synonym: "NDEA" RELATED [FlyBase:FBrf0139766] is_a: BFO:0000004 ! independent continuant is_a: CHEBI:34873 ! N-nitrosodiethylamine is_a: CHEBI:35803 ! nitrosamine [Term] id: FBcv:0000736 name: heat sensitive amorphic allele namespace: allele_class def: "An allele that completely lacks function (i.e. whose gene productive is completely inactive) at high temperatures, but that retains at least some function at lower temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000688 ! amorphic allele is_a: FBcv:0000739 ! temperature conditional amorphic allele is_a: FBcv:0000746 ! heat sensitive loss of function allele intersection_of: FBcv:0000688 ! amorphic allele intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000737 name: temperature conditional amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function at some temperatures (restrictive temperatures) but not others (permissive temperatures) from the observation that addition of extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000288 ! amorphic allele - genetic evidence is_a: FBcv:0000739 ! temperature conditional amorphic allele intersection_of: FBcv:0000288 ! amorphic allele - genetic evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000738 name: edited book namespace: pub_type def: "A publication that is not issued on a regular, ongoing basis containing separate articles or chapters (typically reviews) written by different authors on a single subject or related subjects, overseen by one or more editors." [FBC:SM] is_a: FBcv:0000652 ! compendium created_by: djs93 creation_date: 2012-07-10T04:05:08Z [Term] id: FBcv:0000739 name: temperature conditional amorphic allele namespace: allele_class def: "An allele that completely lacks function (i.e. whose gene productive is completely inactive) at some temperatures, but not others." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000688 ! amorphic allele is_a: FBcv:0000745 ! temperature conditional loss of function allele intersection_of: FBcv:0000688 ! amorphic allele intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000740 name: cold sensitive amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000288 ! amorphic allele - genetic evidence is_a: FBcv:0000737 ! temperature conditional amorphic allele - genetic evidence is_a: FBcv:0001003 ! cold sensitive amorphic allele intersection_of: FBcv:0000288 ! amorphic allele - genetic evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000741 name: heat sensitive amorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures) from the observation that adding extra copies in the genome has no effect on the phenotype at the restrictive temperatures. Most commonly, evidence takes the form of the observation that the phenotype of homozygotes (2 copies) is identical to that seen when the allele is in trans to a deletion of the gene (1 copy)." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000288 ! amorphic allele - genetic evidence is_a: FBcv:0000736 ! heat sensitive amorphic allele is_a: FBcv:0000737 ! temperature conditional amorphic allele - genetic evidence intersection_of: FBcv:0000288 ! amorphic allele - genetic evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000742 name: cold sensitive amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures)." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000689 ! amorphic allele - molecular evidence is_a: FBcv:0000744 ! temperature conditional amorphic allele - molecular evidence is_a: FBcv:0001003 ! cold sensitive amorphic allele intersection_of: FBcv:0000689 ! amorphic allele - molecular evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000743 name: heat sensitive amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function at high temperatures (restrictive temperatures) but not at low temperatures (permissive temperatures)." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000689 ! amorphic allele - molecular evidence is_a: FBcv:0000736 ! heat sensitive amorphic allele is_a: FBcv:0000744 ! temperature conditional amorphic allele - molecular evidence intersection_of: FBcv:0000689 ! amorphic allele - molecular evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000744 name: temperature conditional amorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to completely lack function at some temperatures (restrictive temperatures) but not at others (permissive temperatures)." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000689 ! amorphic allele - molecular evidence is_a: FBcv:0000739 ! temperature conditional amorphic allele intersection_of: FBcv:0000689 ! amorphic allele - molecular evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000745 name: temperature conditional loss of function allele namespace: allele_class def: "An allele that at some temperatures but not others either makes no functional gene product or makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000287 ! loss of function allele intersection_of: FBcv:0000287 ! loss of function allele intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000746 name: heat sensitive loss of function allele namespace: allele_class def: "An allele that at high temperatures but not low temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000287 ! loss of function allele is_a: FBcv:0000745 ! temperature conditional loss of function allele intersection_of: FBcv:0000287 ! loss of function allele intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000747 name: cold sensitive loss of function allele namespace: allele_class def: "An allele that at low temperatures but not high temperatures, either makes no functional gene product, makes reduced levels of a normally functioning gene product or makes a gene product with reduced activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000287 ! loss of function allele is_a: FBcv:0000745 ! temperature conditional loss of function allele intersection_of: FBcv:0000287 ! loss of function allele intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000748 name: temperature conditional gain of function allele namespace: allele_class def: "An allele that at some temperatures but not others, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000290 ! gain of function allele intersection_of: FBcv:0000290 ! gain of function allele intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000749 name: heat sensitive gain of function allele namespace: allele_class def: "An allele that at high temperatures but not low temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000290 ! gain of function allele is_a: FBcv:0000748 ! temperature conditional gain of function allele intersection_of: FBcv:0000290 ! gain of function allele intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000750 name: cold sensitive gain of function allele namespace: allele_class def: "An allele that at low temperatures but not high temperatures, either makes a normally functioning gene product but at higher levels or in a different spatial or temporal pattern to wild-type, or a product with increased or novel activity compared to wild-type." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000290 ! gain of function allele is_a: FBcv:0000748 ! temperature conditional gain of function allele intersection_of: FBcv:0000290 ! gain of function allele intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000751 name: temperature conditional hypomorphic allele namespace: allele_class def: "An allele that, at some temperatures but not others, makes a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000690 ! hypomorphic allele is_a: FBcv:0000745 ! temperature conditional loss of function allele intersection_of: FBcv:0000690 ! hypomorphic allele intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000752 name: heat sensitive hypomorphic allele namespace: allele_class def: "An allele that makes a gene product that is functionally equivalent to wild-type but which at high temperatures is present in a lesser amount or with lowered activity, and that retains normal levels of expression or activity at low temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000690 ! hypomorphic allele is_a: FBcv:0000746 ! heat sensitive loss of function allele is_a: FBcv:0000751 ! temperature conditional hypomorphic allele intersection_of: FBcv:0000690 ! hypomorphic allele intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000753 name: cold sensitive hypomorphic allele namespace: allele_class def: "An allele that makes a gene product that is functionally equivalent to wild-type but which at low temperatures is present in a lesser amount or with lowered activity, and that retains normal function at higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000690 ! hypomorphic allele is_a: FBcv:0000747 ! cold sensitive loss of function allele is_a: FBcv:0000751 ! temperature conditional hypomorphic allele intersection_of: FBcv:0000690 ! hypomorphic allele intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000754 name: temperature conditional hypomorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to have normal activity at some temperatures (permissive temperatures) but at other temperatures to make a gene product with normal function but in a lesser amount or with lowered activity (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy))." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000289 ! hypomorphic allele - genetic evidence is_a: FBcv:0000751 ! temperature conditional hypomorphic allele intersection_of: FBcv:0000289 ! hypomorphic allele - genetic evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000755 name: cold sensitive hypomorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to have normal activity at high temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at lower temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy))." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000289 ! hypomorphic allele - genetic evidence is_a: FBcv:0000753 ! cold sensitive hypomorphic allele is_a: FBcv:0000754 ! temperature conditional hypomorphic allele - genetic evidence intersection_of: FBcv:0000289 ! hypomorphic allele - genetic evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000756 name: heat sensitive hypomorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to have normal activity at low temperatures (permissive temperatures) but to make a gene product with normal function but in a lesser amount or with lowered activity at higher temperatures (non-permissive temperatures). The genetic evidence must consist of an observation extra copies in the genome decrease the expressivity and/or penetrance of the phenotype at non-permissive temperatures. Most commonly this evidence takes the form of experiments showing that the homozygote (2 copies) has a weaker phenotype at non-permissive temperatures than the allele in trans to a deletion of the gene (1 copy))." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000289 ! hypomorphic allele - genetic evidence is_a: FBcv:0000752 ! heat sensitive hypomorphic allele is_a: FBcv:0000754 ! temperature conditional hypomorphic allele - genetic evidence intersection_of: FBcv:0000289 ! hypomorphic allele - genetic evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000757 name: temperature conditional hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a normal gene product in normal amounts at some temperatures, but at other temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000691 ! hypomorphic allele - molecular evidence is_a: FBcv:0000751 ! temperature conditional hypomorphic allele intersection_of: FBcv:0000691 ! hypomorphic allele - molecular evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000758 name: cold sensitive hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a normal gene product in normal amounts at high temperatures, but at lower temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000691 ! hypomorphic allele - molecular evidence is_a: FBcv:0000753 ! cold sensitive hypomorphic allele is_a: FBcv:0000757 ! temperature conditional hypomorphic allele - molecular evidence intersection_of: FBcv:0000691 ! hypomorphic allele - molecular evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000759 name: heat sensitive hypomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a normal gene product in normal amounts at low temperatures, but at higher temperatures to make a gene product that is functionally equivalent to wild-type but in a lesser amount or with lowered activity." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000691 ! hypomorphic allele - molecular evidence is_a: FBcv:0000752 ! heat sensitive hypomorphic allele is_a: FBcv:0000757 ! temperature conditional hypomorphic allele - molecular evidence intersection_of: FBcv:0000691 ! hypomorphic allele - molecular evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000760 name: temperature conditional antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at some temperatures, but not others." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000695 ! antimorphic allele is_a: FBcv:0000748 ! temperature conditional gain of function allele intersection_of: FBcv:0000695 ! antimorphic allele intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000761 name: heat sensitive antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at high temperatures, but not at lower temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000695 ! antimorphic allele is_a: FBcv:0000749 ! heat sensitive gain of function allele is_a: FBcv:0000760 ! temperature conditional antimorphic allele intersection_of: FBcv:0000695 ! antimorphic allele intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000762 name: cold sensitive antimorphic allele namespace: allele_class def: "An allele that makes a gene product that is antagonistic to the function of the wild-type gene product at cold temperatures, but not at higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000695 ! antimorphic allele is_a: FBcv:0000750 ! cold sensitive gain of function allele is_a: FBcv:0000760 ! temperature conditional antimorphic allele intersection_of: FBcv:0000695 ! antimorphic allele intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000763 name: temperature conditional antimorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make a gene product that is antagonistic to the wild-type gene product at some temperatures (restrictive temperatures) but not at others (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000292 ! antimorphic allele - genetic evidence is_a: FBcv:0000760 ! temperature conditional antimorphic allele intersection_of: FBcv:0000292 ! antimorphic allele - genetic evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000764 name: cold sensitive antimorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make a gene product that is antagonistic to the wild-type gene product at low temperatures (restrictive temperatures) but not at high temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000292 ! antimorphic allele - genetic evidence is_a: FBcv:0000762 ! cold sensitive antimorphic allele is_a: FBcv:0000763 ! temperature conditional antimorphic allele - genetic evidence intersection_of: FBcv:0000292 ! antimorphic allele - genetic evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000765 name: heat sensitive antimorphic allele - genetic evidence namespace: allele_class def: "An allele inferred to make a gene product that is antagonistic to the wild-type gene product at high temperatures (restrictive temperatures) but not at lower temperatures (permissive temperatures) from the observation that, at the non-permissive temperatures, the phenotype over a deficiency is stronger than that over a wild-type allele, which in turn is stronger than that in the presence of a duplication of the wild-type locus." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000292 ! antimorphic allele - genetic evidence is_a: FBcv:0000761 ! heat sensitive antimorphic allele is_a: FBcv:0000763 ! temperature conditional antimorphic allele - genetic evidence intersection_of: FBcv:0000292 ! antimorphic allele - genetic evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000766 name: temperature conditional antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at some temperatures but not others." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000694 ! antimorphic allele - molecular evidence is_a: FBcv:0000760 ! temperature conditional antimorphic allele intersection_of: FBcv:0000694 ! antimorphic allele - molecular evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000767 name: cold sensitive antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at low temperatures but not higher temperatures." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000694 ! antimorphic allele - molecular evidence is_a: FBcv:0000762 ! cold sensitive antimorphic allele is_a: FBcv:0000766 ! temperature conditional antimorphic allele - molecular evidence intersection_of: FBcv:0000694 ! antimorphic allele - molecular evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000768 name: heat sensitive antimorphic allele - molecular evidence namespace: allele_class def: "An allele that has been shown by molecular evidence to make a gene product that is antagonistic to the function of the wild-type gene product at high temperatures but not lower temperatures." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000694 ! antimorphic allele - molecular evidence is_a: FBcv:0000761 ! heat sensitive antimorphic allele is_a: FBcv:0000766 ! temperature conditional antimorphic allele - molecular evidence intersection_of: FBcv:0000694 ! antimorphic allele - molecular evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000769 name: temperature conditional neomorphic allele namespace: allele_class def: "An allele that, at some temperatures but not others, makes a gene product with a novel function or expression pattern compared to wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000697 ! neomorphic allele is_a: FBcv:0000748 ! temperature conditional gain of function allele intersection_of: FBcv:0000697 ! neomorphic allele intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000770 name: heat sensitive neomorphic allele namespace: allele_class def: "An allele that, at some high temperatures but not lower temperatures, makes a gene product with a novel function or expression pattern compared to wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000697 ! neomorphic allele is_a: FBcv:0000749 ! heat sensitive gain of function allele is_a: FBcv:0000769 ! temperature conditional neomorphic allele intersection_of: FBcv:0000697 ! neomorphic allele intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000771 name: cold sensitive neomorphic allele namespace: allele_class def: "An allele that, at some low temperatures but not higher temperatures, makes a gene product at with a novel function or expression pattern compared to wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000697 ! neomorphic allele is_a: FBcv:0000750 ! cold sensitive gain of function allele is_a: FBcv:0000769 ! temperature conditional neomorphic allele intersection_of: FBcv:0000697 ! neomorphic allele intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000772 name: temperature conditional neomorphic allele - genetic evidence namespace: allele_class def: "An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some temperatures (non-permissive temperatures) but not others (permissive temperatures) based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000291 ! neomorphic allele - genetic evidence is_a: FBcv:0000769 ! temperature conditional neomorphic allele intersection_of: FBcv:0000291 ! neomorphic allele - genetic evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000773 name: cold sensitive neomorphic allele - genetic evidence namespace: allele_class def: "An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some low temperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000291 ! neomorphic allele - genetic evidence is_a: FBcv:0000771 ! cold sensitive neomorphic allele is_a: FBcv:0000772 ! temperature conditional neomorphic allele - genetic evidence intersection_of: FBcv:0000291 ! neomorphic allele - genetic evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000774 name: heat sensitive neomorphic allele - genetic evidence namespace: allele_class def: "An allele that, is inferred to make a gene product with a novel function or expression pattern compared to wild-type at some high temperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), based on the evidence that the phenotype at the non-permissive temperature is unaffected by extra or fewer doses of the wild-type gene." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000291 ! neomorphic allele - genetic evidence is_a: FBcv:0000770 ! heat sensitive neomorphic allele is_a: FBcv:0000772 ! temperature conditional neomorphic allele - genetic evidence intersection_of: FBcv:0000291 ! neomorphic allele - genetic evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000775 name: temperature conditional neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at some temperatures but not others." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000692 ! neomorphic allele - molecular evidence is_a: FBcv:0000769 ! temperature conditional neomorphic allele intersection_of: FBcv:0000692 ! neomorphic allele - molecular evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000776 name: cold sensitive neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at low temperatures but not higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000692 ! neomorphic allele - molecular evidence is_a: FBcv:0000771 ! cold sensitive neomorphic allele is_a: FBcv:0000775 ! temperature conditional neomorphic allele - molecular evidence intersection_of: FBcv:0000692 ! neomorphic allele - molecular evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000777 name: heat sensitive neomorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to produce a gene product with a novel function or expression pattern (compared to wild-type) at high temperatures but not lower temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000692 ! neomorphic allele - molecular evidence is_a: FBcv:0000770 ! heat sensitive neomorphic allele is_a: FBcv:0000775 ! temperature conditional neomorphic allele - molecular evidence intersection_of: FBcv:0000692 ! neomorphic allele - molecular evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000778 name: temperature conditional hypermorphic allele namespace: allele_class def: "An allele that, at some temperatures but not others, makes a gene product with normal function but at higher levels or with higher activity than in wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000696 ! hypermorphic allele is_a: FBcv:0000748 ! temperature conditional gain of function allele intersection_of: FBcv:0000696 ! hypermorphic allele intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:57:02Z [Term] id: FBcv:0000779 name: heat sensitive hypermorphic allele namespace: allele_class def: "An allele that, at high temperatures but not lower temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000696 ! hypermorphic allele is_a: FBcv:0000749 ! heat sensitive gain of function allele is_a: FBcv:0000778 ! temperature conditional hypermorphic allele intersection_of: FBcv:0000696 ! hypermorphic allele intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:54:34Z [Term] id: FBcv:0000780 name: cold sensitive hypermorphic allele namespace: allele_class def: "An allele that, at low temperatures but not higher temperatures, makes a gene product with normal function but at higher levels or with higher activity than in wild-type.." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000696 ! hypermorphic allele is_a: FBcv:0000750 ! cold sensitive gain of function allele is_a: FBcv:0000778 ! temperature conditional hypermorphic allele intersection_of: FBcv:0000696 ! hypermorphic allele intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0000781 name: temperature conditional hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at some temperatures (non-permissive temperatures) but not others (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000293 ! hypermorphic allele - genetic evidence is_a: FBcv:0000778 ! temperature conditional hypermorphic allele intersection_of: FBcv:0000293 ! hypermorphic allele - genetic evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000782 name: cold sensitive hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at low temperatures (non-permissive temperatures) but not higher temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000293 ! hypermorphic allele - genetic evidence is_a: FBcv:0000780 ! cold sensitive hypermorphic allele is_a: FBcv:0000781 ! temperature conditional hypermorphic allele - genetic evidence intersection_of: FBcv:0000293 ! hypermorphic allele - genetic evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000783 name: heat sensitive hypermorphic allele - genetic evidence namespace: allele_class def: "An allele inferred from genetic evidence to make a normal gene product at increased levels or with increased activity compared to wild-type, where this increased amount or activity is present at high temperatures (non-permissive temperatures) but not lower temperatures (permissive temperatures), and where the genetic evidence consists of the observation that extra copies in the genome increase the expressivity and/or penetrance of the phenotype at the non-permissive temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000293 ! hypermorphic allele - genetic evidence is_a: FBcv:0000779 ! heat sensitive hypermorphic allele is_a: FBcv:0000781 ! temperature conditional hypermorphic allele - genetic evidence intersection_of: FBcv:0000293 ! hypermorphic allele - genetic evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000784 name: temperature conditional hypermorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at some temperatures but not others." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000693 ! hypermorphic allele - molecular evidence is_a: FBcv:0000778 ! temperature conditional hypermorphic allele intersection_of: FBcv:0000693 ! hypermorphic allele - molecular evidence intersection_of: conditionality FBcv:0000310 ! temperature conditional relationship: conditionality FBcv:0000310 ! temperature conditional created_by: djs93 creation_date: 2012-03-22T03:55:17Z [Term] id: FBcv:0000785 name: cold sensitive hypermorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at low temperatures but not higher temperatures." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000693 ! hypermorphic allele - molecular evidence is_a: FBcv:0000780 ! cold sensitive hypermorphic allele is_a: FBcv:0000784 ! temperature conditional hypermorphic allele - molecular evidence intersection_of: FBcv:0000693 ! hypermorphic allele - molecular evidence intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive created_by: djs93 creation_date: 2012-03-22T03:58:31Z [Term] id: FBcv:0000786 name: heat sensitive hypermorphic allele - molecular evidence namespace: allele_class def: "An allele shown by molecular evidence to make a functionally wild-type gene product at increased levels or with increased activity where this increased expression or activity occurs at high temperatures but not lower temperatures." [FBC:DOS, FlyBase:FBrf0049147] is_a: FBcv:0000693 ! hypermorphic allele - molecular evidence is_a: FBcv:0000779 ! heat sensitive hypermorphic allele is_a: FBcv:0000784 ! temperature conditional hypermorphic allele - molecular evidence intersection_of: FBcv:0000693 ! hypermorphic allele - molecular evidence intersection_of: conditionality FBcv:0000311 ! heat sensitive relationship: conditionality FBcv:0000311 ! heat sensitive created_by: djs93 creation_date: 2012-03-22T03:59:43Z [Term] id: FBcv:0000787 name: journal namespace: pub_type def: "A publication issued on a regular, ongoing basis containing separate research articles and other writings such as reviews, comments and conference reports." [FBC:SM, MeSH:D020492] synonym: "Periodicals" RELATED [MeSH:D020492] xref: MeSH:D020492 is_a: FBcv:0000652 ! compendium created_by: djs93 creation_date: 2012-07-10T04:08:06Z [Term] id: FBcv:0000788 name: newspaper article namespace: pub_type def: "A work consisting of a news item appearing in a general-interest newspaper or other general news periodical, containing information of current and timely interest in the field of medicine or science." [FBC:SM, MeSH:D018431] xref: MeSH:D018431 is_a: FBcv:0000189 ! publication class created_by: djs93 creation_date: 2012-07-10T04:17:34Z [Term] id: FBcv:0000789 name: sequence record namespace: pub_type def: "A record of a nucleotide or protein sequence in some standard format." [FBC:SM] is_a: FBcv:0000189 ! publication class created_by: djs93 creation_date: 2012-07-10T05:42:47Z [Term] id: FBcv:0000790 name: database namespace: pub_type def: "Work consisting of a structured file of information or a set of logically related data stored and retrieved using computer-based means." [FBC:SM, MeSH:D019991] xref: MeSH:D019991 is_a: FBcv:0000189 ! publication class created_by: djs93 creation_date: 2012-07-13T02:06:57Z [Term] id: FBcv:0000791 name: delayed aging namespace: phenotypic_class def: "A phenotype in which the aging process (GO:0007568) is slower than in wild-type." [FBC:DOC] is_a: FBcv:0000384 ! abnormal aging [Term] id: FBcv:0000792 name: premature aging namespace: phenotypic_class def: "A phenotype in which the aging process (GO:0007568) is accelerated compared to wild-type." [FBC:DOC] is_a: FBcv:0000384 ! abnormal aging [Term] id: FBcv:0000793 name: progressive namespace: temporal_qualifier def: "A phenotype that becomes more severe with age." [FBC:DOS] is_a: FBcv:0000176 ! temporal qualifier created_by: djs93 creation_date: 2012-10-10T12:02:35Z [Term] id: FBcv:0000797 name: cell autonomy qualifier namespace: genotype_to_phenotype_relation def: "Cell autonomy statements describe the cellular focus of mutant phenotype, generally revealed by genetic mosaic analysis, in terms of whether the mutant has its phenotypic effect limited to, or not limited to, cells of the mutant genotype." [FBC:rd] subset: do_not_annotate is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000799 name: obsolete gene descriptor is_obsolete: true [Term] id: FBcv:0000801 name: obsolete polymorphism assay is_obsolete: true [Term] id: FBcv:0000803 name: obsolete RFLP synonym: "restriction fragment length polymorphism" RELATED [] is_obsolete: true [Term] id: FBcv:0000805 name: obsolete DNA sequence variant is_obsolete: true [Term] id: FBcv:0000807 name: allele descriptor def: "Descriptor that relates to aspects of an allele." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000013 ! descriptor [Term] id: FBcv:0000809 name: phenotype qualifier def: "Qualifier that describes an observable phenotype." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000005 ! qualifier [Term] id: FBcv:0000811 name: qualitative qualifier def: "Qualifier that describes a particular quality of an observable phenotype." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000812 name: clone of cells namespace: clone_qualifier def: "A clone of cells that share a genotype." [FBC:DOS] synonym: "clone qualifier" RELATED [] is_a: FBcv:0000809 ! phenotype qualifier [Term] id: FBcv:0000813 name: nitrogen mustard namespace: origin_of_mutation def: "Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR." [CHEBI:37598] synonym: "2-chloro-N-(2-chloroethyl)-N-methylethanamine" RELATED [] synonym: "CB1414" RELATED [] synonym: "HN2" RELATED [] synonym: "mechlorethamine" RELATED [] synonym: "mutation induced by nitrogen mustard exposure" EXACT [] is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:37598 ! nitrogen mustard is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000814 name: 1,4-dimethanesulfonoxybutane namespace: origin_of_mutation def: "A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant." [CHEBI:28901] synonym: "busulfan" RELATED [CHEBI:28901] synonym: "CB2041" RELATED [] synonym: "mutation induced by 1,4-dimethanesulfonoxybutane exposure" EXACT [] synonym: "mutation induced by busulfan exposure" EXACT [] is_a: CHEBI:25223 ! methanesulfonate ester is_a: CHEBI:28901 ! busulfan is_a: FBcv:0000526 ! alkylating agent [Term] id: FBcv:0000815 name: p-N,N-di-(2-chloroethyl)aminophenylbutyric acid namespace: origin_of_mutation def: "A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia." [CHEBI:28830] synonym: "CB1348" RELATED [] synonym: "chlorambucil" EXACT [CHEBI:28830] synonym: "mutation induced by chlorambucil exposure" EXACT [] synonym: "mutation induced by p-N,N-di-(2-chloroethyl)aminophenylbutyric acid exposure" EXACT [] is_a: CHEBI:25384 ! monocarboxylic acid is_a: CHEBI:28830 ! chlorambucil is_a: CHEBI:33860 ! aromatic amine is_a: CHEBI:36683 ! organochlorine compound is_a: CHEBI:37598 ! nitrogen mustard is_a: CHEBI:50996 ! tertiary amino compound is_a: FBcv:0000813 ! nitrogen mustard [Term] id: FBcv:0001003 name: cold sensitive amorphic allele def: "An allele that completely lacks function (i.e. whose gene productive is completely inactive) at low temperatures, but that retains at least some function at higher temperatures." [FBC:DOS, FlyBase:FBrf0002371, FlyBase:FBrf0049147] is_a: FBcv:0000688 ! amorphic allele is_a: FBcv:0000739 ! temperature conditional amorphic allele is_a: FBcv:0000747 ! cold sensitive loss of function allele intersection_of: FBcv:0000688 ! amorphic allele intersection_of: conditionality FBcv:0000312 ! cold sensitive relationship: conditionality FBcv:0000312 ! cold sensitive [Term] id: FBcv:0001315 name: beta-estradiol conditional namespace: environmental_qualifier def: "Phenotype expressed only in the presence of beta-estradiol (CHEBI:16469)." [FBC:DOS] synonym: "conditional beta-estradiol" EXACT [] is_a: FBcv:0000313 ! drug conditional [Term] id: FBcv:0001324 name: obsolete endocytosis defective namespace: phenotypic_class def: "Phenotype that is a defect in endocytosis (GO:0006897). 'endocytosis' is defined as: 'A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.'" [FBC:DOS] comment: Obsoleted as this is phenotype is too molecular to be captured by FlyBase phenotype curation and will be captured by GO curation [FBC:CP]. synonym: "abnormal endocytosis" EXACT [] is_obsolete: true [Term] id: FBcv:0001325 name: obsolete exocytosis defective namespace: phenotypic_class def: "Phenotype that is a defect in exocytosis (GO:0006887). 'exocytosis' is defined as: 'A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.'" [] comment: Obsoleted as this is phenotype is too molecular to be captured by FlyBase phenotype curation and will be captured by GO curation [FBC:CP]. synonym: "abnormal exocytosis" EXACT [] is_obsolete: true [Term] id: FBcv:0001347 name: phenotype namespace: phenotypic_class def: "Any abnormality in or loss of some anatomical structure or biological process compared to wild-type." [FBC:DOS] comment: The subclasses of this term classify Drosophila phenotypes into different common categories. They have been chosen by FlyBase to reflect phenotype terms most often reported by Drosophila researchers in the published literature. subset: do_not_annotate synonym: "phenotypic class" EXACT [] is_a: FBcv:0000347 ! phenotypic class [Term] id: FBcv:0001500 name: minos activity namespace: origin_of_mutation def: "Mutation induced by the transposable activity caused by Minos, a DNA transposable element. The minos element is 1.4 kilobases in length with 254 base pairs inverted terminal repeats. It specifically targets TA dinucleotides and generates a flanking duplication of 2 base pairs upon insertion. Mobilization is induced by the activity of the minos transposase." [FBC:DOS, FlyBase:FBrf0202435] synonym: "mutation induced by minos activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity [Term] id: FBcv:0002000 name: lethal - all die before end of P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages prior to eclosion from the pupal case (the end of the P-stage)." [FBC:DOS] comment: As the P-Stage and the 'pharate adult stage' have the same end, there is no need for a separate term for 'lethal - all die before end of pharate adult stage. subset: lethal_phase synonym: "lethal - all die before end of pharate adult stage" EXACT [] synonym: "pupal lethal" BROAD [] is_a: FBcv:0000351 ! lethal [Term] id: FBcv:0002001 name: lethal - all die before end of first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the first instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002003 ! lethal - all die before end of second instar larval stage [Term] id: FBcv:0002002 name: lethal - all die before end of larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the larval stage." [FBC:DOS] comment: As the larval stage and third instar larval stage have the same end, there is no need for a separate term for 'lethal - all die before end of third instar larval stage'. subset: lethal_phase synonym: "larval lethal" BROAD [] synonym: "lethal - all die before end of third instar larval stage" EXACT [] is_a: FBcv:0002026 ! lethal - all die before end of prepupal stage [Term] id: FBcv:0002003 name: lethal - all die before end of second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the second instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002002 ! lethal - all die before end of larval stage [Term] id: FBcv:0002004 name: increased mortality namespace: phenotypic_class def: "A phenotype that is an increase in the rate of death in a population at any stage of life (during development or adulthood), over the rate seen in a wild type control population." [FBC:DOS] subset: fbcvsubset_mgiribbons subset: lethal_phase is_a: FBcv:0001347 ! phenotype [Term] id: FBcv:0002005 name: lethal - all die during P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the P-stage." [FBC:DOS] subset: lethal_phase synonym: "pupal lethal" BROAD [] is_a: FBcv:0002000 ! lethal - all die before end of P-stage is_a: FBcv:0002010 ! majority die during P-stage [Term] id: FBcv:0002006 name: lethal - all die during first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the first instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002001 ! lethal - all die before end of first instar larval stage is_a: FBcv:0002007 ! lethal - all die during larval stage is_a: FBcv:0002011 ! majority die during first instar larval stage [Term] id: FBcv:0002007 name: lethal - all die during larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the larval stage." [FBC:DOS] subset: lethal_phase synonym: "larval lethal" BROAD [] is_a: FBcv:0002002 ! lethal - all die before end of larval stage is_a: FBcv:0002012 ! majority die during larval stage [Term] id: FBcv:0002008 name: lethal - all die during second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the second instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002003 ! lethal - all die before end of second instar larval stage is_a: FBcv:0002007 ! lethal - all die during larval stage is_a: FBcv:0002013 ! majority die during second instar larval stage [Term] id: FBcv:0002009 name: lethal - all die during third instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the third instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002007 ! lethal - all die during larval stage is_a: FBcv:0002014 ! majority die during third instar larval stage [Term] id: FBcv:0002010 name: majority die during P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the P-stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002011 name: majority die during first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the first instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002012 ! majority die during larval stage is_a: FBcv:0002021 ! some die during first instar larval stage [Term] id: FBcv:0002012 name: majority die during larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002013 name: majority die during second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the second instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002012 ! majority die during larval stage is_a: FBcv:0002022 ! some die during second instar larval stage [Term] id: FBcv:0002014 name: majority die during third instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the third instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002012 ! majority die during larval stage is_a: FBcv:0002024 ! some die during third instar larval stage [Term] id: FBcv:0002015 name: partially lethal namespace: phenotypic_class def: "A phenotype of a population that is the death of some significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS, FBC:KM] subset: lethal_phase is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002019 name: increased mortality during development namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population prior to becoming a mature adult, where mature is defined as after adult stage A3 (FBdv:00006012)." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002004 ! increased mortality [Term] id: FBcv:0002020 name: some die during P-stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the P-stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002021 name: some die during first instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the first instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002022 name: some die during second instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the second instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002023 name: some die during larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002024 name: some die during third instar larval stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the third instar larval stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002023 ! some die during larval stage [Term] id: FBcv:0002025 name: lethal - all die during pharate adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the pharate adult stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002005 ! lethal - all die during P-stage is_a: FBcv:0002036 ! majority die during pharate adult stage [Term] id: FBcv:0002026 name: lethal - all die before end of prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the prepupal stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002027 ! lethal - all die before end of pupal stage [Term] id: FBcv:0002027 name: lethal - all die before end of pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the pupal stage." [FBC:DOS] subset: lethal_phase synonym: "pupal lethal" BROAD [] is_a: FBcv:0002000 ! lethal - all die before end of P-stage [Term] id: FBcv:0002030 name: lethal - all die during pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the pupal stage." [FBC:DOS] subset: lethal_phase synonym: "pupal lethal" BROAD [] is_a: FBcv:0002005 ! lethal - all die during P-stage is_a: FBcv:0002027 ! lethal - all die before end of pupal stage is_a: FBcv:0002034 ! majority die during pupal stage [Term] id: FBcv:0002031 name: lethal - all die during prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the prepupal stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002005 ! lethal - all die during P-stage is_a: FBcv:0002026 ! lethal - all die before end of prepupal stage is_a: FBcv:0002035 ! majority die during prepupal stage [Term] id: FBcv:0002032 name: obsolete lethal - all die before end of embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population at some stage or stages before the end of the embryonic stage." [FBC:DOS] comment: Obsoleted due to equivalence with FBcv:0002033 'lethal - all die during embryonic stage'. is_obsolete: true replaced_by: FBcv:0002033 [Term] id: FBcv:0002033 name: lethal - all die during embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population during the embryonic stage." [FBC:DOS] subset: lethal_phase synonym: "embryonic lethal" EXACT [] is_a: FBcv:0002001 ! lethal - all die before end of first instar larval stage is_a: FBcv:0002037 ! majority die during embryonic stage [Term] id: FBcv:0002034 name: majority die during pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the pupal stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002010 ! majority die during P-stage is_a: FBcv:0002039 ! some die during pupal stage [Term] id: FBcv:0002035 name: majority die during prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the prepupal stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002010 ! majority die during P-stage is_a: FBcv:0002040 ! some die during prepupal stage [Term] id: FBcv:0002036 name: majority die during pharate adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the pharate adult stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002010 ! majority die during P-stage is_a: FBcv:0002038 ! some die during pharate adult stage [Term] id: FBcv:0002037 name: majority die during embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population during the embryonic stage." [FBC:DOS] comment: This term is agnostic about whether any survive to adulthood. subset: lethal_phase is_a: FBcv:0002041 ! some die during embryonic stage [Term] id: FBcv:0002038 name: some die during pharate adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the pharate adult stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002039 name: some die during pupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the pupal stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002040 name: some die during prepupal stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the prepupal stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002020 ! some die during P-stage [Term] id: FBcv:0002041 name: some die during embryonic stage namespace: phenotypic_class def: "A phenotype of a population that is the death of a significant proportion of animals in that population during the embryonic stage." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0002042 name: lethal - all die during immature adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of all animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012))." [FBC:DOS] subset: lethal_phase is_a: FBcv:0000351 ! lethal is_a: FBcv:0002050 ! majority die during immature adult stage [Term] id: FBcv:0002050 name: majority die during immature adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of the majority of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012))." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002051 ! some die during immature adult stage [Term] id: FBcv:0002051 name: some die during immature adult stage namespace: phenotypic_class def: "A phenotype of a population that is the death of some significant number of animals in that population as immature adults (after eclosion but before the end of adult stage A3 (FBdv:00006012))." [FBC:DOS] subset: lethal_phase is_a: FBcv:0002019 ! increased mortality during development [Term] id: FBcv:0003000 name: disease qualifier namespace: disease_qualifier def: "Qualifier that describes aspects of genetic models of disease." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000005 ! qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003001 name: ameliorates namespace: disease_qualifier def: "Makes a condition better." [FBC:ST] comment: The 'ameliorates' term is used in FlyBase disease annotation when an allele interacts to remove or reduce the severity of the disease phenotype associated with a given disease model (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003002 name: DOES NOT ameliorate namespace: disease_qualifier def: "Contrary to expectation, does not make a condition better." [FBC:ST] comment: The 'DOES NOT ameliorate' term is used in FlyBase disease annotation when an allele is expected to remove or reduce the severity of the disease phenotype associated with a given disease model but fails to do so. is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003003 name: DOES NOT exacerbate namespace: disease_qualifier def: "Contrary to expectation, does not make a condition worse." [FBC:ST] comment: The 'DOES NOT exacerbate' term is used in FlyBase disease annotation when an allele is expected to makes the disease phenotype associated with a given disease model more severe but fails to do so (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003004 name: DOES NOT model namespace: disease_qualifier def: "Contrary to expectation, characteristics associated with a given condition are not recapitulated in a different system." [FBC:ST] comment: The 'DOES NOT model' term is used in FlyBase disease annotation when an allele is expected to recapitulate one or more aspects of a particular human disease phenotype in Drosophila but fails to do so (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003005 name: exacerbates namespace: disease_qualifier def: "Makes a condition worse." [FBC:ST] comment: The 'exacerbates' term is used in FlyBase disease annotation when an allele interacts to make the disease phenotype associated with a given disease model more severe (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003006 name: model of namespace: disease_qualifier def: "Characteristics associated with a given condition recapitulated in a different system." [FBC:ST] comment: The 'model of' term is used in FlyBase disease annotation when alleles (typically of fly or human genes) recapitulate one or more aspect of a human disease phenotype in Drosophila (FBC:ST). is_a: FBcv:0003000 ! disease qualifier created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003007 name: site specific cleavage namespace: origin_of_mutation def: "Sequence change induced by a cleavage event that is caused by an endonuclease that recognizes and cleaves specific sequences in double stranded DNA causing double-strand breaks (DSB)." [FlyBase:FBrf0202435] synonym: "change induced by site specific cleavage" EXACT [] is_a: FBcv:0000452 ! origin of mutation created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003008 name: CRISPR/Cas9 namespace: origin_of_mutation def: "Sequence change caused by a cleavage of a specific DNA sequence induced by CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 nuclease system. This system relies on the transcription of a chimeric guide RNA (gRNA) which directs the Cas9 endonuclease to a specified DNA sequence through basepairing to 20 nucleotide CRISPR target sites. These sites are located next to a 3 nucleotide protospacer adjacent motif (PAM) required for DNA cleavage." [FlyBase:FBrf0222128, FlyBase:FBrf0222292, FlyBase:FBrf0222617, UniProt:Q99ZW2] synonym: "change induced by CRISPR/Cas9 endonuclease cleavage" EXACT [] synonym: "CRISPR/Cas9 endonuclease" RELATED [] is_a: FBcv:0003007 ! site specific cleavage created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003009 name: TALEN namespace: origin_of_mutation def: "Sequence change caused by the cleavage of specific DNA sequences by transcription activator-like effector nucleases (TALENs). TALEN proteins comprise a DNA binding domain fused to the catalytic domain of the FokI endonuclease. The DNA binding domain contains a repetitive region within the middle of the protein, consisting of tandem repeats of 34 amino acid segments, with each of these segments recognizing a single base pair. The specificity of the binding is determined by two hypervariable amino acids in positions 12 and 13 (repeat-variable diresidues). Cleavage requires dimerization of FokI. The endonuclease is directed to a target region by a pair of TALENs which bind to adjacent sequences separated by a spacer region, allowing dimerization and promoting cleavage." [PMID:10954606, PMID:20660643] synonym: "change induced by TALE endonuclease cleavage" EXACT [] synonym: "TALE endonuclease" RELATED [] is_a: FBcv:0003007 ! site specific cleavage created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003010 name: phiC31 integrase namespace: origin_of_mutation def: "Sequence change caused by a site specific recombination catalyzed by the serine recombinase phiC31 integrase that recognizes a minimal high-efficiency attP recognition site of 39 base pairs and a minimal high-efficiency attB recognition site of 34 base pairs. The attP and attB sites contain imperfect inverted repeats flanking a short recombination core (TTG) that provides directionality." [FlyBase:FBrf0174693, FlyBase:FBrf0201927, UniProt:Q9T221] synonym: "change induced by phiC31 integrase recombination" EXACT [] is_a: FBcv:0000478 ! site specific recombination created_by: mmc46 creation_date: 2014-03-27T11:07:29Z [Term] id: FBcv:0003011 name: group descriptor namespace: group_descriptor def: "Descriptor that relates aspects of the grouping of genes or gene products." [FBC:MMC] subset: do_not_annotate is_a: FBcv:0000013 ! descriptor created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003012 name: gene or gene product group namespace: group_descriptor def: "Genes or gene products that are acknowledged to form a natural biological group." [FBC:SM] is_a: FBcv:0003011 ! group descriptor created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003013 name: gene array group namespace: group_descriptor def: "Two or more genes contiguously arranged where the individual genes are either identical in sequence, or essentially so (SO:0005851)." [FBC:SM, SO:ma] is_a: FBcv:0003012 ! gene or gene product group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003014 name: functional group namespace: group_descriptor def: "Genes whose products share a common biological and/or molecular function." [FBC:SM] is_a: FBcv:0003012 ! gene or gene product group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003015 name: gene complex group namespace: group_descriptor def: "Genes with the same location on the chromosome and whose products have a similar function." [FBC:SM, http://www.sdbonline.org/fly/aignfam/ensplitc.htm] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003016 name: protein complex group namespace: group_descriptor def: "Genes whose protein products form a macromolecular complex (GO:0043234)." [FBC:SM, GOC:go_curators] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003017 name: pathway group namespace: group_descriptor def: "Genes whose products act in a specified signal transduction or metabolic pathway." [FBC:SM] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003018 name: process group namespace: group_descriptor def: "Genes whose products act in a specified biological process." [FBC:SM] is_a: FBcv:0003014 ! functional group created_by: mmc46 creation_date: 2014-03-28T15:23:42Z [Term] id: FBcv:0003019 name: I-element activity namespace: origin_of_mutation def: "Mutation caused by the transposable activity caused by the I-element, a non-LTR retrotransposon. The I-element is 5371 base pairs long. Mobilization is induced by the activity of the I-element transposase." [FlyBase:FBrf0202435] synonym: "mutation induced by I-element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity created_by: mmc46 creation_date: 2014-09-16T13:30:48Z [Term] id: FBcv:0003020 name: Stalker element activity namespace: origin_of_mutation def: "Mutation caused by the transposable activity caused by the Stalker element, a LTR retrotransposon. Mobilization is induced by the activity of the stalker element transposase." [FlyBase:FBrf0202435] synonym: "mutation induced by Stalker element activity" EXACT [] is_a: FBcv:0000483 ! transposable element activity created_by: mmc46 creation_date: 2014-09-16T13:30:48Z [Term] id: FBcv:0003021 name: dataset descriptor def: "Term that describes a dataset." [FBC:GD] is_a: FBcv:0000013 ! descriptor created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003022 name: dataset entity type namespace: dataset_entity_type def: "Term that specifies the dataset component type." [FBC:GD] is_a: FBcv:0003021 ! dataset descriptor created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003023 name: project namespace: dataset_entity_type def: "A set of biological data from a single study. Corresponds to the NCBI bioproject, GEO series or SRA study." [FBC:GD] is_a: FBcv:0003022 ! dataset entity type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003024 name: biosample namespace: dataset_entity_type def: "Biological source material characterized by an experiment." [FBC:GD] is_a: FBcv:0003022 ! dataset entity type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003025 name: assay namespace: dataset_entity_type def: "Quantitative or qualitative assessment of biological source material to measure some attribute." [FBC:GD] is_a: FBcv:0003022 ! dataset entity type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003026 name: result namespace: dataset_entity_type def: "Analysis of raw data generated by an assay(s) that makes some conclusion." [FBC:GD] is_a: FBcv:0003022 ! dataset entity type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003027 name: reagent collection namespace: dataset_entity_type def: "A collection of material reagents." [FBC:GD] is_a: FBcv:0003022 ! dataset entity type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003028 name: dataset data type def: "The data type content of a dataset." [FBC:GD] is_a: FBcv:0003021 ! dataset descriptor created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003029 name: project type namespace: project_type def: "The type of project as characterized its data content." [FBC:GD] is_a: FBcv:0003028 ! dataset data type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003030 name: umbrella project namespace: project_type def: "A project that groups together related sub-projects." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003031 name: genome namespace: project_type def: "A project that characterizes an organism's genome sequence." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003032 name: genome variation namespace: project_type def: "A project that characterizes the intraspecific variation of an organism's genome." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003033 name: genome binding namespace: project_type def: "A project that characterizes the occupancy profile of a factor that binds directly or indirectly to the genome." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003034 name: transcriptome namespace: project_type def: "A project that characterizes the set of transcribed RNA sequences expressed by the genome." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003035 name: proteome namespace: project_type def: "A project that characterizes the set of proteins expressed in an organism." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003036 name: interactome namespace: project_type def: "A project that characterizes the set of inter-molecular interactions in an organism." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003037 name: metabolome namespace: project_type def: "A project that characterizes the set of small molecules in an organism." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003038 name: phenotypic screen namespace: project_type def: "A project that searches for the genes responsible for a particular observable trait." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003039 name: chemical screen namespace: project_type def: "A project that searches for chemicals, natural or synthetic, that elicit some biological effect." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003040 name: gene model annotation namespace: project_type def: "A project that constructs models describing the set of transcripts and polypeptides encoded by some group of genes." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003041 name: phylogenetic analysis namespace: project_type def: "A project that reconstructs the evolutionary history of a group of genes or organisms." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003042 name: reagent namespace: project_type def: "A project that describes a large material resource that is accessible to the community." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003043 name: other namespace: project_type def: "A project type that is not described by other more specific terms." [FBC:GD] is_a: FBcv:0003029 ! project type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003044 name: biosample type namespace: biosample_type def: "The type of biosample as characterized by its biological source material." [FBC:GD] is_a: FBcv:0003028 ! dataset data type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003045 name: whole organism namespace: biosample_type def: "A biosample that comprises the whole animal." [FBC:GD] is_a: FBcv:0003044 ! biosample type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003046 name: tissue namespace: biosample_type def: "A biosample derived from a multicellular structure comprising similar cells with some specific function, typically isolated by dissection." [FBC:GD] is_a: FBcv:0003044 ! biosample type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003047 name: isolated cells namespace: biosample_type def: "A biosample containing dissociated cells isolated from the organism, typically isolated by affinity capture or sorting methods." [FBC:GD] is_a: FBcv:0003044 ! biosample type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003048 name: primary cell line namespace: biosample_type def: "A biosample consisting of cells that were isolated from animal tissue and cultured in vitro for a limited amount of time." [FBC:GD] is_a: FBcv:0003044 ! biosample type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003049 name: immortalized cell line namespace: biosample_type def: "A biosample consisting of cells isolated from animal tissue that have acquired the ability to proliferate indefinitely." [FBC:GD] is_a: FBcv:0003044 ! biosample type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003050 name: assay type namespace: assay_type def: "The type of assay as characterized by its data content." [FBC:GD] is_a: FBcv:0003028 ! dataset data type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003051 name: CAGE-Seq namespace: assay_type def: "An assay of 5' capped transcripts, using CAGE to biotinylate and isolate the 7-methylguanosine cap, with subsequent characterization by high-throughput sequencing." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003052 name: ChIP-chip namespace: assay_type def: "A genome binding assay of some factor as characterized by chromatin immunoprecipitation (ChIP) of that factor and analysis of co-purifying DNA fragments using genome tiling array." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003053 name: ChIP-Seq namespace: assay_type def: "A genome binding assay of some factor as characterized by chromatin immunoprecipitation (ChIP) of that factor and high-throughput sequencing of co-purifying DNA fragments." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003054 name: CLiP-Seq namespace: assay_type def: "An RNA binding assay of some protein as characterized by cross-linking immunoprecipitation (CLiP) and high-throughput sequencing of co-purifying RNA fragments." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003055 name: DamID-chip namespace: assay_type def: "A genome binding assay of some protein as characterized by creating a fusion to DNA adenine methyltransferase and analysis of methylated DNA sequences by genome tiling array." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003056 name: DamID-Seq namespace: assay_type def: "A genome binding assay of some protein as characterized by creating a fusion to DNA adenine methyltransferase and analysis of methylated DNA sequences by high-throughput sequencing." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003057 name: DNase-chip namespace: assay_type def: "An assay that characterizes the genome's DNase hypersensitivity using genome tiling array." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003058 name: DNase-Seq namespace: assay_type def: "An assay that characterizes the genome's DNase hypersensitivity using high-throughput sequencing." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003059 name: FAIRE-Seq namespace: assay_type def: "An assay that characterizes transcriptional regulatory elements using formaldehyde-assisted isolation of regulatory elements (FAIRE) and high-throughput sequencing." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003060 name: GRO-Seq namespace: assay_type def: "An assay that maps the genome-wide position, orientation and amount of transcriptionally engaged RNA polymerase by global run-on sequencing." [PMID:19056941] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003061 name: MNase-chip namespace: assay_type def: "An assay that maps nucleosome positions by using micrococcal nuclease to cleave linker DNA with the subsequent isolation of mononucleosomal DNA fragments that are characterized by genome tiling array." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003062 name: MNase-Seq namespace: assay_type def: "An assay that maps nucleosome positions by using micrococcal nuclease to cleave linker DNA with the subsequent isolation of mononucleosomal DNA fragments that are characterized by high-throughput sequencing." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003063 name: RAMPAGE-Seq namespace: assay_type def: "An assay of 5'-capped transcripts using the orthogonal approaches of reverse transcriptase template-switching and cap-trapping, with subsequent characterization by high-throughput sequencing." [PMID:22936248] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003064 name: Repli-Seq namespace: assay_type def: "An assay mapping genomic replication patterns by labeling newly synthesized DNA in vivo with 5-bromo-2-deoxyuridine (BrdU), with subsequent affinity purification and characterization by high-throughput sequencing." [PMID:19966280] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003065 name: Ribo-Seq namespace: assay_type def: "Ribosome profiling, an assay in which mRNA fragments protected by ribosomes are isolated and characterized by high-throughput sequencing." [PMID:22056041] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003066 name: RIP-Seq namespace: assay_type def: "An assay in which a factor is immunoprecipitated and the associated RNA sequences are characterized by high-throughput sequencing." [PMID:21051541] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003067 name: RNA expression microarray namespace: assay_type def: "Measurement of global transcript abundance by hybridization of cDNA to an oligonucleotide array, in which the array contains a set of probes designed with complementarity to each annotated transcript." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003068 name: RNA-Seq namespace: assay_type def: "A quantitative method for mapping transcribed regions, in which complementary DNA fragments are subjected to high-throughput sequencing." [PMID:18451266] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003069 name: RNA tiling array namespace: assay_type def: "Measurement of transcribed regions across the genome by hybridization of cDNA to an oligonucleotide array, in which the genome is represented by oligonucleotides at regularly spaced intervals." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003070 name: short RNA-Seq namespace: assay_type def: "An assay characterizing of small RNA species 17-35 nt in size by high-throughput sequencing." [FBC:GD] is_a: FBcv:0003068 ! RNA-Seq created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003071 name: protein mass spectrometry namespace: assay_type def: "An assay that identifies and characterizes of proteins and their post-translational modifications by mass spectrometry." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003072 name: lipid mass spectrometry namespace: assay_type def: "An assay that identifies and characterizes lipids by mass spectrometry." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003073 name: carbohydrate mass spectrometry namespace: assay_type def: "An assay that identifies and characterizes complex carbohydrates by mass spectrometry." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003074 name: metabolite mass spectrometry namespace: assay_type def: "An assay that identifies and characterizes small metabolites by mass spectrometry." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003075 name: affinity purification and mass spectrometry namespace: assay_type def: "An assay that identifies the molecules that interact with a particular bait factor by mass spectrometry." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003076 name: two hybrid screen namespace: assay_type def: "An assay that tests proteins pairwise for interaction by fusing each to separate, complementary domains of some protein, usually a transcription factor. Upon interaction, the proximity of the complementary domains generates reporter activity." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003077 name: RNAi screen namespace: assay_type def: "An assay that uses a panel of RNA interference (RNAi) reagents to systematically knockdown a large set of genes, one at a time, to identify those that are involved in some biological process." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003078 name: deficiency screen namespace: assay_type def: "An assay that uses a panel of deficiencies to systematically delete large segments of the genome to identify those segments that are involved in some biological process." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003079 name: genetic screen namespace: assay_type def: "An assay that uses a large set of mutations to identify genes that are involved in some biological process." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003080 name: comparative genomic hybridization by array namespace: assay_type def: "An assay that characterizes copy number variation of the genome in a sample using genome tiling array." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003081 name: whole genome shotgun sequencing namespace: assay_type def: "An assay of genomic sequence that generates a large number of random genomic sequences, typically derived from paired-end sequencing of genomic fragments, that together give a complete (albeit scrambled) representation of the entire genome." [FBC:GD] is_a: FBcv:0003050 ! assay type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003082 name: result type namespace: result_type def: "The type of result as characterized by its data content." [FBC:GD] is_a: FBcv:0003028 ! dataset data type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003083 name: genetic map namespace: result_type def: "A result that maps the relative position of genetic markers, where distances are measured by recombination frequency." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003084 name: physical map namespace: result_type def: "A result that maps the relative position of genes and other sequence landmarks." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003085 name: whole genome shotgun assembly namespace: result_type def: "A result in which a collection of whole genome shotgun sequences is combined to build successively larger contigs." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003086 name: genome assembly namespace: result_type def: "The result of reconstruction of the genome achieved by aligning and merging smaller fragments." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003087 name: reference genome assembly namespace: result_type def: "The result of extensive sequence alignment and merging to produce a genome assembly that serves as the current reference for a particular organism." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003088 name: gene expression profile namespace: result_type def: "A result that provides the expression values for all (or some subset) of genes in a given biological sample." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003089 name: RNA-seq profile namespace: result_type def: "A result that profiles expressed RNA-seq sequences along genome." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003090 name: genome binding profile namespace: result_type def: "A result that profiles the genome occupancy for some factor." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003091 name: mRNA translation profile namespace: result_type def: "A result of Ribo-seq analysis that profiles ribosome protected sequences along the genome." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003092 name: TSS identification namespace: result_type def: "An analysis that results in the identification of discrete transcription start site regions." [FBC:GD] is_a: FBcv:0003108 ! analysis created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003093 name: poly(A) site identification namespace: result_type def: "An analysis that results in the identification of discrete polyadenylation sites." [FBC:GD] is_a: FBcv:0003108 ! analysis created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003094 name: exon junction identification namespace: result_type def: "An analysis that results in the identification of discrete exon junctions." [FBC:GD] is_a: FBcv:0003108 ! analysis created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003095 name: editing site identification namespace: result_type def: "An analysis that results in the identification of discrete A-to-I RNA editing sites." [FBC:GD] is_a: FBcv:0003108 ! analysis created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003096 name: binding site identification namespace: result_type def: "An analysis that results in the identification of discrete DNA or RNA binding sites." [FBC:GD] is_a: FBcv:0003108 ! analysis created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003097 name: differential gene expression analysis namespace: result_type def: "An analysis that results from the comparison of expression profiles for different conditions to identify genes that are regulated by those conditions." [FBC:GD] is_a: FBcv:0003108 ! analysis created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003098 name: expression clustering namespace: result_type def: "The analysis of a gene expression profiles to define sets of genes that share similar expression characteristics." [FBC:GD] is_a: FBcv:0003108 ! analysis created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003099 name: expression cluster namespace: result_type def: "A result that represents a set of genes that share similar expression characteristics across some set of conditions." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003100 name: gene list namespace: result_type def: "A result that represents a set of genes that have some shared characteristic." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003101 name: protein-protein interaction namespace: result_type def: "A result that represents a set of protein-protein interactions for a given sample." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003102 name: RNA-protein interaction namespace: result_type def: "A result that represents a set of RNA-protein interactions for a given sample." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003103 name: RNA-RNA interaction namespace: result_type def: "A result that represents a set of RNA-RNA interactions for a given sample." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003104 name: metabolite profile namespace: result_type def: "A result that represents a set of small molecules identified for a given sample." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003105 name: phenotypic profile namespace: result_type def: "A result that represents the range of phenotypes obtained for a set of genetic perturbations." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003106 name: genomic copy number profile namespace: result_type def: "A result that represents the copy number variation across the genome for a given sample." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003107 name: liftover file namespace: result_type def: "A result that represents the mapping of coordinates between two different genome assemblies for a given species." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003108 name: analysis namespace: result_type def: "A result that is produced from the detailed examination of data to come to some conclusion." [FBC:GD] is_a: FBcv:0003082 ! result type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003109 name: reagent collection type namespace: reagent_collection_type def: "The type of reagent collection as characterized by the material resources comprised by the collection." [FBC:GD] is_a: FBcv:0003028 ! dataset data type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003110 name: aberration stock collection namespace: reagent_collection_type def: "A collection of large chromosomal aberrations, available as fly stocks, which may include duplications, deletions, inversions or translocations." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003111 name: allele collection namespace: reagent_collection_type def: "A collection of alleles that are available as fly stocks." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003112 name: cDNA library namespace: reagent_collection_type def: "A collection of cDNAs available as plasmids." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003113 name: construct collection namespace: reagent_collection_type def: "A collection of transgenic constructs that are available as fly stocks." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003114 name: dsRNA amplicon collection namespace: reagent_collection_type def: "A collection of PCR products used for the synthesis of double-stranded RNA to induce RNA-interference." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003115 name: RNAi construct collection namespace: reagent_collection_type def: "A collection of transgenic constructs, available as fly stocks, designed to target gene knockdown by RNA-interference." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003116 name: genomic clone collection namespace: reagent_collection_type def: "A collection of genomic DNA clones available as plasmids. This may include BAC, YAC, fosmid, cosmid and P1 clone collections." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003117 name: fly strain collection namespace: reagent_collection_type def: "A collection of wild-type fly strains." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003118 name: transgenic insertion collection namespace: reagent_collection_type def: "A collection of transgenic construct insertions available as fly stocks." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003119 name: TE insertion stock collection namespace: reagent_collection_type def: "A collection of transposable element insertions available as fly stocks." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003120 name: microarray library namespace: reagent_collection_type def: "A collection of hybridization targets on a microarray." [FBC:GD] is_a: FBcv:0003109 ! reagent collection type created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003121 name: dataset attribute def: "A descriptor that describes some aspect of a dataset." [FBC:GD] is_a: FBcv:0003021 ! dataset descriptor created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003122 name: project attribute namespace: project_attribute def: "A descriptor that describes some aspect of a project." [FBC:GD] is_a: FBcv:0003121 ! dataset attribute created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003123 name: study design namespace: project_attribute def: "The aim of the project investigation, as defined by the key variables in the set of experiments." [FBC:GD] is_a: FBcv:0003122 ! project attribute created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003124 name: species study namespace: project_attribute def: "A project study design that aims to compare different species." [FBC:GD] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003125 name: strain study namespace: project_attribute def: "A project study design that aims to compare different wild-type strains for a given species." [FBC:GD] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003126 name: sex study namespace: project_attribute def: "A project study design that aims to characterize the biological mechanisms responsible for the development or maintenance of the sex-related properties of an organism." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003127 name: developmental stage study namespace: project_attribute def: "A project study design investigating the biological mechanisms responsible for the control or maintenance of development." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003128 name: circadian rhythm study namespace: project_attribute def: "A project study design investigating the biological mechanisms responsible for the control or maintenance of circadian rhythm." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003129 name: cell cycle study namespace: project_attribute def: "A project study design investigating the biological mechanisms of the cell responsible for maintaining or controlling aspects of the cell cycle." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003130 name: tissue type study namespace: project_attribute def: "A project study design investigating the biological mechanisms of intact or dissected tissues in order to understand their form or function." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003131 name: cell type study namespace: project_attribute def: "A project study design involving the use of cultured or extracted cells with an investigative focus of studying a cellular property." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003132 name: subcellular component study namespace: project_attribute def: "A project study design examining subcellular components of cells including organelles, the nucleus, or any other grouping of intra- or extracellular material." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003133 name: gene study namespace: project_attribute def: "A project study design in which the goal of the study is to examine properties of a specific gene or set of genes." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003134 name: biotic stimulus study namespace: project_attribute def: "A project study design investigating the effects of a biotic stimulus on some aspect of an organism." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003135 name: chemical stimulus study namespace: project_attribute def: "A project study design investigating the effects of a chemical stimulus on some aspect of an organism." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003136 name: physical stimulus study namespace: project_attribute def: "A project study design investigating the effects of a physical stimulus on some aspect of an organism." [FBC:CT] is_a: FBcv:0003123 ! study design created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003137 name: biosample attribute namespace: biosample_attribute def: "Characteristics pertaining to the growth conditions, treatments and tissue isolation methods used to generate and obtain a biosample." [FBC:GD] is_a: FBcv:0003121 ! dataset attribute created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003138 name: biosample scope namespace: biosample_attribute def: "The scope and purity of a biosample, ranging from single cell to environmental sample." [http://www.ncbi.nlm.nih.gov/books/NBK54364/] is_a: FBcv:0003137 ! biosample attribute created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003139 name: single cell sample namespace: biosample_attribute def: "A biosample that is derived from only a single cell." [FBC:CT] is_a: FBcv:0003138 ! biosample scope created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003140 name: single individual sample namespace: biosample_attribute def: "A biosample that is derived from one individual." [FBC:CT] is_a: FBcv:0003138 ! biosample scope created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003141 name: multi-individual sample namespace: biosample_attribute def: "A biosample that is derived from multiple individuals." [FBC:CT] is_a: FBcv:0003138 ! biosample scope created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003142 name: multispecies sample namespace: biosample_attribute def: "A biosample that is derived from multiple species." [FBC:CT] is_a: FBcv:0003138 ! biosample scope created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003143 name: environmental namespace: biosample_attribute def: "A biosample derived from an environmental sample for which the species content is unknown." [http://www.ncbi.nlm.nih.gov/books/NBK54364/] is_a: FBcv:0003138 ! biosample scope created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003144 name: artificial namespace: biosample_attribute def: "A biosample that was synthesized in a laboratory." [http://www.ncbi.nlm.nih.gov/books/NBK54364/] is_a: FBcv:0003138 ! biosample scope created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003145 name: wild caught namespace: biosample_attribute def: "A sample that originated from a wild caught population and is considered true wild type." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003146 name: growth condition namespace: biosample_attribute def: "Growth conditions and treatments used to culture the organism prior to biosample isolation." [FBC:GD] is_a: FBcv:0003137 ! biosample attribute created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003147 name: trait selection namespace: biosample_attribute def: "An inbred strain is subjected to artificial laboratory selection of some trait over the course of several generations." [FBC:GD] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003148 name: interspecific hybrid namespace: biosample_attribute def: "A sample that is derived from a controlled mating between individuals of two specific species." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003149 name: mated namespace: biosample_attribute def: "A sample in which the individuals have undergone mating." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003150 name: virgin namespace: biosample_attribute def: "A sample in which the individuals have not undergone mating." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003151 name: constant dark namespace: biosample_attribute def: "A sample that is maintained in conditions comparable to constant darkness." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003152 name: constant light namespace: biosample_attribute def: "A sample that is maintained in conditions comparable to constant light." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003153 name: light-dark cycle namespace: biosample_attribute def: "A sample that is maintained in conditions with a specific cycle that included exposure to both light and darkness." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003154 name: primary cell culture namespace: biosample_attribute def: "A sample that is derived from a primary cell culture." [FBC:CT] is_a: FBcv:0003146 ! growth condition created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003155 name: cell culture property namespace: biosample_attribute def: "Characteristics pertaining to the cell culture conditions used to generate the biosample." [FBC:GD] is_a: FBcv:0003137 ! biosample attribute created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003156 name: transiently transfected cell line namespace: biosample_attribute def: "A sample that contains a transfected agent which is not incorporated into the genome." [FBC:CT] is_a: FBcv:0003155 ! cell culture property created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003157 name: stably transfected cell line namespace: biosample_attribute def: "A sample that contains a transfected agent which has been stably incorporated into the genome." [FBC:CT] is_a: FBcv:0003155 ! cell culture property created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003158 name: log phase cells namespace: biosample_attribute def: "A sample that is derived from a population of cells undergoing a log phase of division." [FBC:CT] is_a: FBcv:0003155 ! cell culture property created_by: mmc46 creation_date: 2016-02-24T19:19:21Z [Term] id: FBcv:0003159 name: stationary phase cells namespace: biosample_attribute def: "A sample that is derived from a popul