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last updated: 2025-12-14 RT after BA fixed inconsistencies
file_name: SOP-105-B_1 QuickColor Test Signage.md
file_date: 2022-08-26
title: FloodLAMP QMS SOP-105-B_1 QuickColor Test Signage
category: guides
subcategory: qms-sops
tags:
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gfile_url: https://docs.google.com/document/d/1IO3MjHxGCzMMlYJsnHvZyzYv-ohpRolbGJksY8S08-E
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pdf_gdrive_url: https://drive.google.com/file/d/1RR_V3e6fn0g7xCESHnX3t-6VYQi3r1NU
pdf_github_url: https://github.com/FocusOnFoundationsNonprofit/floodlamp-archive/blob/main/guides/qms-sops/SOP-105-B_1%20QuickColor%20Test%20Signage.pdf
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license: CC BY 4.0 - https://creativecommons.org/licenses/by/4.0/
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words: 309
notes:
summary_short: The FloodLAMP QMS SOP-105-B_1 QuickColor Test Signage is a print-ready, step-by-step bench guide for running the QuickColor assay from sample intake through reporting results. It summarizes key workflow actions and parameters, including 1XISS dilution ratios, inactivation heating/cooling times for water bath or dry heat block, reaction mix component volumes for common reaction counts, and 65 °C amplification timing. The signage also highlights contamination-control reminders (cleaning tubes, one tube open at a time) and imaging/logging instructions for reporting.
CONTENT
FloodLAMP Biotechnologies
**Document Number:** SOP-105-B_1
**Effective Date:** 08/26/2022
**Version:** 1
***INTERNAL TITLE:*** QuickColor Test Signage
Print Format
1\) Intake Sample Tubes
---
- **Clean tubes - spray wipe with ethanol/alcohol and wipe tubes**
- **Intake with App (can also do during Amp heating)**
2\) Make 1X Inactivation Saline Solution
---
- **Add 100X Inactivation Solution to Saline**
| | | |
|:----------------------:|:-----------------------:|:-----------------------:|
| **Saline**
**5 mL** | **Saline**
**15 mL** | **Saline**
**50 mL** |
| **100X IS**
**50 μL** | **100X IS**
**150 μL** | **100X IS**
**500 μL** |
||
3\) Add 1X Inactivation Saline Solution to Sample Tubes
---
- **Add 1mL of inactivation saline solution (1XISS) to each sample tube**
- **One sample tube open at a time**
4\) Heat to Inactivate Samples
---
- **Water Bath (set at 99°C)**
**Heat 8 mintues**
**Cool 10 minutes**
- **Dry Heat Block for 1.5mL sample tubes (set at 95°C)**
**Heat 5 mintues**
**Cool 5 minutes**
5\) Make Reaction Mix
---
- **Add CLAMP MM and Primer Soln (PGS) to 1.5mL tube**
- **Aliquot into Strip8 tubes or 96 well PCR Plate**
| | | | |
|:--------:|:--------:|:--------:|:--------:|
| **8 Rxns** | **16 Rxns** | **24 Rxns** | **48 Rxns** |
| **PGS**
**92 μL** | **PGS**
**183 μL** | **PGS**
**275 μL** | **PGS**
**550 μL** |
| **CLAMP MM**
**109 μL** | **CLAMP MM**
**218 μL** | **CLAMP MM**
**328 μL** | **CLAMP MM**
**655 μL** |
||
6\) Add Sample to Reaction
---
- **Add 2μL from each sample tube to corresponding well**
- **Pipet up and down 5 times, blowout in liquid, tip touch**
7\) Heat Amp Reactions
---
- **Heat at 65ºC for 25 min**
- **Set personal timer (on phone) for 24 min**
8\) Log and Report Results
---
- **Let samples cool for at least 1 minute before taking photo**
- **Crop and apply vivid filter**
- **Log Amp Run Form with QR code link**