13:06:2021 12:12
PSI-MOD
1.2
Joshua Klein
Annotation note 01 - "[PSI-MOD:ref]" has been replaced by PubMed:18688235.
Annotation note 02 - When an entry in the RESID Database is annotated with different sources because the same modification can arise from different encoded amino acids, then the PSI-MOD definition for each different source instance carries the RESID cross-reference followed by a hash symbol "#" and a 3 or 4 character label. When an entry in the RESID Database is annotated as a general modification with the same enzymatic activity producing different chemical structures depending on natural variation in the nonproteinaceous substrate, on secondary modifications that do not change the nature of the primary modification, or on a combination of a primary and one or more secondary modifications on the same residue, then the PSI-MOD definition for each different instance carries the RESID cross-reference followed by the special tag "#var".
Annotation note 03 - When an entry in the Unimod database is annotated as a general modification, and one or more instance sites are listed, then the PSI-MOD definition for each different site instance carries the Unimod cross-reference followed by a hash symbol and an amino acid code, "N-term" or "C-term".
Annotation note 04 - The elemental formulas are in strict alphabetical order, not in CAS ("C" and "H" first) order. Isotope numbers are in parentheses before the element symbol, and an element should not occur in a formula both with and without an isotope number. In difference formulas, counts can be zero or negative.
Annotation note 05 - In entries with an isotope indicator in the formula, average masses are meaningless and are assigned the value equal to the monoisotopic mass, but rounded to a lower precision; monoisotopic masses are calculated by using the masses for the indicated isotopes and the most common isotopes for other elements without isotope indicators in the formulas.
Annotation note 06 - For cross-link modifications, the number following "Cross-link" in the comment record indicates the number of amino acid residues that appear in the origin record, used to check the difference formula and masses. This usage differs from RESID, where the cross-link number indicates the maximum number of peptide chains that can be cross-linked.
Annotation note 07 - The synonym cross-reference "MOD:old name" has been replaced by "MOD:alternate name".
Annotation note 08 - The DeltaMass listings for free amino acids have been removed. Most Unimod entries that have not been "approved" have by general agreement not been incorporated unless there has been a request for a specific term by a PRIDE submitter.
Annotation note 09 - The Open Mass Spectrometry Search Algorithm, OMSSA, enumerated list of modifications are being incorporated. The string values are synonyms with the synonymtypedef "OMSSA-label", and their integer values (which are supposed to be stable) are definition cross-references.
Annotation note 10 - GNOme is the Glycan Naming and Subsumption Ontology (https://gnome.glyomics.org/), an ontology for the support of glycomics. PSI-MOD does not have all possible glycans in its entries, just the ones that are noted to be on proteins and have been requested for addition. GNOme uses GlyTouCan (http://glytoucan.org/) to provide stable accessions for glycans described at varyious degrees of characterization, including compositions (no linkage) and topologies (no carbon bond positions or anomeric configurations).
ISO-8601 date: 2022-06-13 12:12Z
PSI-MOD version: 1.031.6
RESID release: 75.00
definition
term replaced by
Label from MS DeltaMass
Short label from OMSSA
Alternate name curated by PSI-MOD
Short label curated by PSI-MOD
subset of protein modifications
Agreed label from MS community
Alternate name from RESID
Misnomer tagged alternate name from RESID
Name from RESID
Systematic name from RESID
Protein feature description from UniProtKB
Alternate name from Unimod
Description (full_name) from Unimod
Interim label from Unimod
subset_property
synonym_type_property
database_cross_reference
has_exact_synonym
has_obo_format_version
has_obo_namespace
has_related_synonym
has_scope
has_synonym_type
in_subset
'Entity A' contains 'Entity B' implies that 'Entity B' is a part of the structure of 'Entity A'.
PSI-MOD
contains
The inverse relationship to "part of".
contains
'Entity A' contains 'Entity B' implies that 'Entity B' is a part of the structure of 'Entity A'.
PubMed:18688235
'Entity A' derives_from 'Entity B' implies that 'Entity A' is chemically derived from 'Entity B'.
PSI-MOD
derives_from
derives from
'Entity A' derives_from 'Entity B' implies that 'Entity A' is chemically derived from 'Entity B'.
PubMed:18688235
'Entity A' has_functional_parent 'Entity B' implies that 'Entity B' has at least one chacteristic group from which 'Entity A' can be derived by functional modification.
PSI-MOD
has_functional_parent
This relationship indicates that the formula and mass of the child are not inherited from the mass of the parent.
has functional parent
'Entity A' has_functional_parent 'Entity B' implies that 'Entity B' has at least one chacteristic group from which 'Entity A' can be derived by functional modification.
PubMed:18688235
'Entity A' part_of 'Entity B' implies that 'Entity A' is a part of the structure of 'Entity B'.
PSI-MOD
part_of
part of
'Entity A' part_of 'Entity B' implies that 'Entity A' is a part of the structure of 'Entity B'.
PubMed:18688235
Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue.
ModRes
PSI-MOD
MOD:00000
protein modification
Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue.
PubMed:18688235
ModRes
A protein modification that effectively replaces a hydrogen atom with an alkyl group.
AlkylRes
PSI-MOD
MOD:00001
alkylated residue
A protein modification that effectively replaces a hydrogen atom with an alkyl group.
PubMed:18688235
AlkylRes
A protein modification that effectively converts an L-serine residue to O3-glycosylserine.
S
natural
OGlycoSer
PSI-MOD
MOD:00002
O-glycosyl-L-serine
OGlycoSer
A protein modification that effectively converts an L-serine residue to O3-glycosylserine.
PubMed:18688235
Entry from Unimod.
PSI-MOD
MOD:00003
This term is for organizational use only and should not be assigned. [JSG]
Unimod
Entry from Unimod.
PubMed:18688235
Artifact entry from Unimod - OBSOLETE because organizational use is no longer required.
PSI-MOD
MOD:00004
artifact
true
Artifact entry from Unimod - OBSOLETE because organizational use is no longer required.
PubMed:18688235
A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine.
T
natural
OGlycoThr
PSI-MOD
MOD:00005
O-glycosyl-L-threonine
A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine.
PubMed:18688235
OGlycoThr
A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond.
NGlycoRes
PSI-MOD
MOD:00006
N-glycosylated residue
A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond.
PubMed:18688235
NGlycoRes
A protein modification that effectively substitutes a selenium atom for a sulfur atom.
46.91
C 0 H 0 N 0 O 0 S -1 Se 1
47.94445
X
natural
Unimod:162
Se(S)Res
PSI-MOD
Delta:S(-1)Se(1)
Selenium replaces sulphur
MOD:00007
selenium substitution for sulfur
A protein modification that effectively substitutes a selenium atom for a sulfur atom.
PubMed:12148805
Unimod:162
Se(S)Res
Delta:S(-1)Se(1)
Selenium replaces sulphur
Entry from Unimod representing one or more entries in RESID. OBSOLETE because organizational use is no longer required.
PSI-MOD
MOD:00008
common
true
Entry from Unimod representing one or more entries in RESID. OBSOLETE because organizational use is no longer required.
PubMed:18688235
A protein modification that removes a residue, or inserts or replaces a residue with a natural, standard or nonstandard, encoded residue.
X
natural
Res
alpha-amino acid
PSI-MOD
MOD:00009
natural residue
A protein modification that removes a residue, or inserts or replaces a residue with a natural, standard or nonstandard, encoded residue.
PubMed:6692818
RESID:AA0000
Res
alpha-amino acid
A protein modification that effectively converts a source amino acid residue to an L-alanine.
0.0
C 0 H 0 N 0 O 0
0.0
C 3 H 5 N 1 O 1
71.08
71.03712
A
natural
(2S)-2-aminopropanoic acid
2-aminopropionic acid
2-azanylpropanoic acid
Ala
L-alanine
alpha-alanine
alpha-aminopropionic acid
PSI-MOD
MOD:00010
L-alanine residue
A protein modification that effectively converts a source amino acid residue to an L-alanine.
ChEBI:29948
DeltaMass:0
PubMed:6692818
RESID:AA0001
(2S)-2-aminopropanoic acid
2-aminopropionic acid
2-azanylpropanoic acid
Ala
L-alanine
alpha-alanine
alpha-aminopropionic acid
A protein modification that effectively converts a source amino acid residue to an L-arginine.
0.0
C 0 H 0 N 0 O 0
0.0
C 6 H 12 N 4 O 1
156.19
156.1011
R
natural
(2S)-2-amino-5-[(diaminomethylidene)amino]pentanoic acid
2-amino-5-(carbamimidamido)pentanoic acid [tautomer]
2-amino-5-[(aminoiminomethyl)amino]pentanoic acid [tautomer]
2-amino-5-guanidinopentanoic acid
2-amino-5-guanidinovaleric acid
2-azanyl-5-[bis(azanyl)methylideneazanyl]pentanoic acid
Arg
L-arginine
alpha-amino-delta-guanidinovaleric acid
PSI-MOD
MOD:00011
L-arginine residue
A protein modification that effectively converts a source amino acid residue to an L-arginine.
ChEBI:29952
DeltaMass:0
PubMed:518876
PubMed:6692818
RESID:AA0002
(2S)-2-amino-5-[(diaminomethylidene)amino]pentanoic acid
2-amino-5-(carbamimidamido)pentanoic acid [tautomer]
2-amino-5-[(aminoiminomethyl)amino]pentanoic acid [tautomer]
2-amino-5-guanidinopentanoic acid
2-amino-5-guanidinovaleric acid
2-azanyl-5-[bis(azanyl)methylideneazanyl]pentanoic acid
Arg
L-arginine
alpha-amino-delta-guanidinovaleric acid
A protein modification that effectively converts a source amino acid residue to an L-asparagine.
0.0
C 0 H 0 N 0 O 0
0.0
C 4 H 6 N 2 O 2
114.1
114.04293
N
natural
(2S)-2-amino-4-butanediamic acid
2,4-bis(azanyl)-4-oxobutanoic acid
2,4-diamino-4-oxobutanoic acid
2-amino-3-carbamoylpropanoic acid
2-amino-4-butanediamic acid
2-aminosuccinamic acid
2-aminosuccinic acid 4-amide
Asn
L-asparagine
alpha-amino-beta-carbamylpropionic acid
alpha-aminosuccinamic acid
aspartic acid 4-amide
aspartic acid beta-amide
beta-asparagine
PSI-MOD
MOD:00012
L-asparagine residue
A protein modification that effectively converts a source amino acid residue to an L-asparagine.
ChEBI:29956
DeltaMass:0
PubMed:15736973
PubMed:5681232
PubMed:6692818
PubMed:9789001
RESID:AA0003
(2S)-2-amino-4-butanediamic acid
2,4-bis(azanyl)-4-oxobutanoic acid
2,4-diamino-4-oxobutanoic acid
2-amino-3-carbamoylpropanoic acid
2-amino-4-butanediamic acid
2-aminosuccinamic acid
2-aminosuccinic acid 4-amide
Asn
L-asparagine
alpha-amino-beta-carbamylpropionic acid
alpha-aminosuccinamic acid
aspartic acid 4-amide
aspartic acid beta-amide
beta-asparagine
A protein modification that effectively converts a source amino acid residue to an L-aspartic acid.
0.0
C 0 H 0 N 0 O 0
0.0
C 4 H 5 N 1 O 3
115.09
115.02694
D
natural
(2S)-2-aminobutanedioic acid
2-azanylbutanedioic acid
Asp
L-aspartic acid
aminosuccinic acid
PSI-MOD
MOD:00013
L-aspartic acid residue
A protein modification that effectively converts a source amino acid residue to an L-aspartic acid.
ChEBI:29958
DeltaMass:0
PubMed:1097438
PubMed:339692
PubMed:4399050
PubMed:5764436
PubMed:6692818
PubMed:8089117
PubMed:9521123
PubMed:9582379
RESID:AA0004
(2S)-2-aminobutanedioic acid
2-azanylbutanedioic acid
Asp
L-aspartic acid
aminosuccinic acid
A protein modification that effectively converts a source amino acid residue to an L-cysteine.
0.0
C 0 H 0 N 0 O 0 S 0
0.0
C 3 H 5 N 1 O 1 S 1
103.14
103.009186
C
natural
(2R)-2-amino-3-sulfanylpropanoic acid
(R)-cysteine
2-amino-3-mercaptopropanoic acid
2-amino-3-mercaptopropionic acid
2-azanyl-3-sulfanylpropanoic acid
3-mercapto-L-alanine
Cys
Cysteine (C, Cys)
L-(+)-cysteine
L-cysteine
alpha-amino-beta-mercaptopropanoic acid
alpha-amino-beta-mercaptopropionic acid
alpha-amino-beta-thiolpropionic acid
beta-mercaptoalanine
half-cystine
thioserine
PSI-MOD
MOD:00014
From DeltaMass: Average Mass: 121.
L-cysteine residue
A protein modification that effectively converts a source amino acid residue to an L-cysteine.
ChEBI:29950
DeltaMass:0
PubMed:1310545
PubMed:15790858
PubMed:3447159
PubMed:6692818
PubMed:7338899
RESID:AA0005
(2R)-2-amino-3-sulfanylpropanoic acid
(R)-cysteine
2-amino-3-mercaptopropanoic acid
2-amino-3-mercaptopropionic acid
2-azanyl-3-sulfanylpropanoic acid
3-mercapto-L-alanine
Cys
Cysteine (C, Cys)
L-(+)-cysteine
L-cysteine
alpha-amino-beta-mercaptopropanoic acid
alpha-amino-beta-mercaptopropionic acid
alpha-amino-beta-thiolpropionic acid
beta-mercaptoalanine
half-cystine
thioserine
A protein modification that effectively converts a source amino acid residue to an L-glutamic acid.
0.0
C 0 H 0 N 0 O 0
0.0
C 5 H 7 N 1 O 3
129.12
129.04259
E
natural
(2S)-2-aminopentanedioic acid
1-aminopropane-1,3-dicarboxylic acid
2-aminoglutaric acid
2-azanylpentanedioic acid
Glu
L-glutamic acid
alpha-aminoglutaric acid
glutaminic acid
PSI-MOD
MOD:00015
L-glutamic acid residue
A protein modification that effectively converts a source amino acid residue to an L-glutamic acid.
ChEBI:29972
DeltaMass:0
PubMed:1881881
PubMed:4565668
PubMed:4922541
PubMed:6692818
PubMed:9326660
PubMed:957425
RESID:AA0006
(2S)-2-aminopentanedioic acid
1-aminopropane-1,3-dicarboxylic acid
2-aminoglutaric acid
2-azanylpentanedioic acid
Glu
L-glutamic acid
alpha-aminoglutaric acid
glutaminic acid
A protein modification that effectively converts a source amino acid residue to an L-glutamine.
0.0
C 0 H 0 N 0 O 0
0.0
C 5 H 8 N 2 O 2
128.13
128.05858
Q
natural
(2S)-2-amino-5-pentanediamic acid
2,5-bis(azanyl)-5-oxopentanoic acid
2,5-diamino-5-oxopentanoic acid
2-amino-4-carbamoylbutanoic acid
2-aminoglutaramic acid
Gln
L-glutamine
alpha-amino-gamma-carbamylbutyric acid
glutamic acid 5-amide
glutamic acid gamma-amide
glutamide
PSI-MOD
MOD:00016
L-glutamine residue
glutamic acid gamma-amide
glutamide
A protein modification that effectively converts a source amino acid residue to an L-glutamine.
ChEBI:30011
DeltaMass:0
PubMed:3340166
PubMed:6692818
PubMed:9342308
RESID:AA0007
(2S)-2-amino-5-pentanediamic acid
2,5-bis(azanyl)-5-oxopentanoic acid
2,5-diamino-5-oxopentanoic acid
2-amino-4-carbamoylbutanoic acid
2-aminoglutaramic acid
Gln
L-glutamine
alpha-amino-gamma-carbamylbutyric acid
glutamic acid 5-amide
A protein modification that effectively converts a source amino acid residue to a glycine.
0.0
C 0 H 0 N 0 O 0
0.0
C 2 H 3 N 1 O 1
57.05
57.021465
G
natural
Gly
aminoacetic acid
aminoethanoic acid
azanylethanoic acid
glycine
glycocoll
PSI-MOD
MOD:00017
glycine residue
A protein modification that effectively converts a source amino acid residue to a glycine.
ChEBI:29947
DeltaMass:0
PubMed:1310545
PubMed:6692818
RESID:AA0008
Gly
aminoacetic acid
aminoethanoic acid
azanylethanoic acid
glycine
glycocoll
A protein modification that effectively converts a source amino acid residue to an L-histidine.
0.0
C 0 H 0 N 0 O 0
0.0
C 6 H 7 N 3 O 1
137.14
137.05891
H
natural
(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid [tautomer]
2-azanyl-3-(1H-imidazol-4-yl)propanoic acid
2-azanyl-3-(1H-imidazol-5-yl)propanoic acid [tautomer]
4-(2-amino-2-carboxyethyl)imidazole
His
L-histidine
alpha-amino-beta-(4-imidazole)propionic acid
glyoxaline-5-alanine
PSI-MOD
MOD:00018
L-histidine residue
A protein modification that effectively converts a source amino acid residue to an L-histidine.
ChEBI:29979
DeltaMass:0
PubMed:14342316
PubMed:2722967
PubMed:512
PubMed:5460889
PubMed:6129252
PubMed:6692818
PubMed:6876174
RESID:AA0009
(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid [tautomer]
2-azanyl-3-(1H-imidazol-4-yl)propanoic acid
2-azanyl-3-(1H-imidazol-5-yl)propanoic acid [tautomer]
4-(2-amino-2-carboxyethyl)imidazole
His
L-histidine
alpha-amino-beta-(4-imidazole)propionic acid
glyoxaline-5-alanine
A protein modification that effectively converts a source amino acid residue to an L-isoleucine.
0.0
C 0 H 0 N 0 O 0
0.0
C 6 H 11 N 1 O 1
113.16
113.08406
I
natural
(2S,3S)-2-amino-3-methylpentanoic acid
2-azanyl-3-methylpentanoic acid
3-methyl-norvaline
Ile
Isoleucyl
L-erythro-isoleucine
L-isoleucine
alpha-amino-beta-methylvaleric acid
PSI-MOD
MOD:00019
L-isoleucine residue
A protein modification that effectively converts a source amino acid residue to an L-isoleucine.
ChEBI:30009
DeltaMass:0
PubMed:6692818
RESID:AA0010
(2S,3S)-2-amino-3-methylpentanoic acid
2-azanyl-3-methylpentanoic acid
3-methyl-norvaline
Ile
Isoleucyl
L-erythro-isoleucine
L-isoleucine
alpha-amino-beta-methylvaleric acid
A protein modification that effectively converts a source amino acid residue to an L-leucine.
0.0
C 0 H 0 N 0 O 0
0.0
C 6 H 11 N 1 O 1
113.16
113.08406
L
natural
(2S)-2-amino-4-methylpentanoic acid
2-azanyl-4-methylpentanoic acid
4-methyl-norvaline
L-leucine
Leu
alpha-amino-gamma-methylvaleric acid
alpha-aminoisocaproic acid
PSI-MOD
MOD:00020
L-leucine residue
A protein modification that effectively converts a source amino acid residue to an L-leucine.
ChEBI:30006
DeltaMass:0
PubMed:11478885
PubMed:6692818
RESID:AA0011
(2S)-2-amino-4-methylpentanoic acid
2-azanyl-4-methylpentanoic acid
4-methyl-norvaline
L-leucine
Leu
alpha-amino-gamma-methylvaleric acid
alpha-aminoisocaproic acid
A protein modification that effectively converts a source amino acid residue to L-lysine.
0.0
C 0 H 0 N 0 O 0
0.0
C 6 H 12 N 2 O 1
128.18
128.09496
K
natural
(2S)-2,6-diaminohexanoic acid
2,6-bis(azanyl)hexanoic acid
6-amino-L-norleucine
ACT_SITE Schiff-base intermediate with substrate
L-lysine
Lys
alpha,epsilon-diaminocaproic acid
PSI-MOD
MOD:00021
L-lysine residue
A protein modification that effectively converts a source amino acid residue to L-lysine.
ChEBI:29967
DeltaMass:0
PubMed:3106962
PubMed:6120171
PubMed:6692818
RESID:AA0012
(2S)-2,6-diaminohexanoic acid
2,6-bis(azanyl)hexanoic acid
6-amino-L-norleucine
ACT_SITE Schiff-base intermediate with substrate
L-lysine
Lys
alpha,epsilon-diaminocaproic acid
A protein modification that effectively converts a source amino acid residue to L-methionine.
0.0
C 0 H 0 N 0 O 0 S 0
0.0
C 5 H 9 N 1 O 1 S 1
131.19
131.04048
M
natural
(2S)-2-amino-4-(methylsulfanyl)butanoic acid
2-amino-4-(methylthio)butanoic acid
2-amino-4-(methylthio)butyric acid
2-azanyl-4-(methylsulfanyl)butanoic acid
L-(-)-methionine
L-methionine
Met
S-methyl-L-homocysteine
alpha-amino-gamma-methylmercaptobutyric acid
alpha-amino-gamma-methylthiobutyric acid
gamma-methylthio-alpha-aminobutyric acid
PSI-MOD
MOD:00022
From DeltaMass: Average Mass: 149
L-methionine residue
A protein modification that effectively converts a source amino acid residue to L-methionine.
ChEBI:29983
DeltaMass:0
PubMed:6411710
PubMed:6692818
RESID:AA0013
(2S)-2-amino-4-(methylsulfanyl)butanoic acid
2-amino-4-(methylthio)butanoic acid
2-amino-4-(methylthio)butyric acid
2-azanyl-4-(methylsulfanyl)butanoic acid
L-(-)-methionine
L-methionine
Met
S-methyl-L-homocysteine
alpha-amino-gamma-methylmercaptobutyric acid
alpha-amino-gamma-methylthiobutyric acid
gamma-methylthio-alpha-aminobutyric acid
A protein modification that effectively converts a source amino acid residue to L-phenylalanine.
0.0
C 0 H 0 N 0 O 0
0.0
C 9 H 9 N 1 O 1
147.18
147.06842
F
natural
(2S)-2-amino-3-phenylpropanoic acid
2-azanyl-3-phenylpropanoic acid
L-phenylalanine
Phe
alpha-amino-beta-phenylpropionic acid
PSI-MOD
MOD:00023
L-phenylalanine residue
A protein modification that effectively converts a source amino acid residue to L-phenylalanine.
ChEBI:29997
DeltaMass:0
PubMed:6692818
RESID:AA0014
(2S)-2-amino-3-phenylpropanoic acid
2-azanyl-3-phenylpropanoic acid
L-phenylalanine
Phe
alpha-amino-beta-phenylpropionic acid
A protein modification that effectively converts a source amino acid residue to L-proline.
0.0
C 0 H 0 N 0 O 0
0.0
C 5 H 7 N 1 O 1
97.12
97.052765
P
natural
(2S)-2-pyrrolidinecarboxylic acid
L-proline
Pro
pyrrolidine-2-carboxylic acid
PSI-MOD
MOD:00024
L-proline residue
A protein modification that effectively converts a source amino acid residue to L-proline.
ChEBI:30017
DeltaMass:0
PubMed:6692818
PubMed:8547259
RESID:AA0015
(2S)-2-pyrrolidinecarboxylic acid
L-proline
Pro
pyrrolidine-2-carboxylic acid
A protein modification that effectively converts a source amino acid residue to L-serine.
0.0
C 0 H 0 N 0 O 0
0.0
C 3 H 5 N 1 O 2
87.08
87.03203
S
natural
(2S)-2-amino-3-hydroxypropanoic acid
2-azanyl-3-hydroxypropanoic acid
3-hydroxy-L-alanine
L-serine
Ser
alpha-amino-beta-hydroxypropionic acid
beta-hydroxyalanine
PSI-MOD
MOD:00025
L-serine residue
A protein modification that effectively converts a source amino acid residue to L-serine.
ChEBI:29999
DeltaMass:0
PubMed:4399050
PubMed:6692818
RESID:AA0016
(2S)-2-amino-3-hydroxypropanoic acid
2-azanyl-3-hydroxypropanoic acid
3-hydroxy-L-alanine
L-serine
Ser
alpha-amino-beta-hydroxypropionic acid
beta-hydroxyalanine
A protein modification that effectively converts a source amino acid residue to L-threonine.
0.0
C 0 H 0 N 0 O 0
0.0
C 4 H 7 N 1 O 2
101.1
101.047676
T
natural
(2S,3R)-2-amino-3-hydroxybutanoic acid
2-azanyl-3-hydroxybutanoic acid
L-threo-threonine
L-threonine
Thr
alpha-amino-beta-hydroxybutyric acid
beta-methylserine
PSI-MOD
MOD:00026
L-threonine residue
A protein modification that effectively converts a source amino acid residue to L-threonine.
ChEBI:30013
DeltaMass:0
PubMed:2989287
PubMed:6692818
RESID:AA0017
(2S,3R)-2-amino-3-hydroxybutanoic acid
2-azanyl-3-hydroxybutanoic acid
L-threo-threonine
L-threonine
Thr
alpha-amino-beta-hydroxybutyric acid
beta-methylserine
A protein modification that effectively converts a source amino acid residue to L-tryptophan.
0.0
C 0 H 0 N 0 O 0
0.0
C 11 H 10 N 2 O 1
186.21
186.07932
W
natural
(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
2-azanyl-3-(1H-indol-3-yl)propanoic acid
L-tryptophan
Trp
alpha-amino-beta-(3-indolyl)propionoic acid
beta(3-indolyl)alanine
PSI-MOD
MOD:00027
L-tryptophan residue
A protein modification that effectively converts a source amino acid residue to L-tryptophan.
ChEBI:29954
DeltaMass:0
PubMed:2059637
PubMed:6692818
PubMed:9324768
RESID:AA0018
(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
2-azanyl-3-(1H-indol-3-yl)propanoic acid
L-tryptophan
Trp
alpha-amino-beta-(3-indolyl)propionoic acid
beta(3-indolyl)alanine
A protein modification that effectively converts a source amino acid residue to L-tyrosine.
0.0
C 0 H 0 N 0 O 0
0.0
C 9 H 9 N 1 O 2
163.18
163.06332
Y
natural
(2S)-2-amino-3-(4-hydoxyphenyl)propanoic acid
2-azanyl-3-(4-hydoxyphenyl)propanoic acid
L-tyrosine
Tyr
alpha-amino-beta-(para-hydroxyphenyl)propionic acid
p-tyrosine
para-hydroxyphenylalanine
PSI-MOD
MOD:00028
L-tyrosine residue
A protein modification that effectively converts a source amino acid residue to L-tyrosine.
ChEBI:29975
DeltaMass:0
PubMed:2190093
PubMed:2542938
PubMed:5550972
PubMed:6061414
PubMed:6120171
PubMed:6692818
RESID:AA0019
(2S)-2-amino-3-(4-hydoxyphenyl)propanoic acid
2-azanyl-3-(4-hydoxyphenyl)propanoic acid
L-tyrosine
Tyr
alpha-amino-beta-(para-hydroxyphenyl)propionic acid
p-tyrosine
para-hydroxyphenylalanine
A protein modification that effectively converts a source amino acid residue to an L-valine.
0.0
C 0 H 0 N 0 O 0
0.0
C 5 H 9 N 1 O 1
99.13
99.06841
V
natural
(2S)-2-amino-3-methylbutanoic acid
2-azanyl-3-methylbutanoic acid
L-valine
Val
alpha-amino-beta-methylbutyric acid
alpha-aminoisovaleric acid
PSI-MOD
MOD:00029
L-valine residue
A protein modification that effectively converts a source amino acid residue to an L-valine.
ChEBI:30015
DeltaMass:0
PubMed:6692818
RESID:AA0020
(2S)-2-amino-3-methylbutanoic acid
2-azanyl-3-methylbutanoic acid
L-valine
Val
alpha-amino-beta-methylbutyric acid
alpha-aminoisovaleric acid
A protein modification that effectively converts a source amino acid residue to an N-formyl-L-methionine, a natural pretranslational modification.
0.0
C 0 H 0 N 0 O 0 S 0
0.0
C 6 H 10 N 1 O 2 S 1
160.21
160.04323
M
natural
N-term
(2S)-2-formylamino-4-(methylsulfanyl)butanoic acid
2-formamido-4-(methylsulfanyl)butanoic acid
2-formylamino-4-(methylthio)butanoic acid
2-formylazanyl-4-(methylsulfanyl)butanoic acid
MOD_RES N-formylmethionine
N-formyl-L-methionine
N-formylated L-methionine
fMet
nformylmet
PSI-MOD
FormylMet
MOD:00030
N-formyl-L-methionine residue
A protein modification that effectively converts a source amino acid residue to an N-formyl-L-methionine, a natural pretranslational modification.
ChEBI:33718
OMSSA:22
PubMed:10825024
PubMed:11152118
PubMed:2165784
PubMed:3042771
PubMed:8758896
RESID:AA0021#FMET
(2S)-2-formylamino-4-(methylsulfanyl)butanoic acid
2-formamido-4-(methylsulfanyl)butanoic acid
2-formylamino-4-(methylthio)butanoic acid
2-formylazanyl-4-(methylsulfanyl)butanoic acid
MOD_RES N-formylmethionine
N-formyl-L-methionine
N-formylated L-methionine
fMet
nformylmet
FormylMet
A protein modification that effectively converts a source amino acid residue to an L-selenocysteine, a natural pretranslational modification.
0.0
C 0 H 0 N 0 O 0 Se 0
0.0
C 3 H 5 N 1 O 1 Se 1
150.05
150.95363
U
natural
(2R)-2-amino-3-selanylpropanoic acid
2-azanyl-3-selanylpropanoic acid
3-selenylalanine
L-selenocysteine
NON_STD Selenocysteine
SeCys
Sec
selenium cysteine
PSI-MOD
MOD:00031
L-selenocysteine residue
A protein modification that effectively converts a source amino acid residue to an L-selenocysteine, a natural pretranslational modification.
ChEBI:30000
PubMed:10523135
PubMed:1066676
PubMed:2037562
PubMed:2963330
PubMed:4734725
PubMed:6076213
PubMed:6217842
PubMed:6714945
RESID:AA0022
(2R)-2-amino-3-selanylpropanoic acid
2-azanyl-3-selanylpropanoic acid
3-selenylalanine
L-selenocysteine
NON_STD Selenocysteine
SeCys
Sec
selenium cysteine
A protein modification that is not chemically categorized.
PSI-MOD
MOD:00032
This term is for organizational use only and should not be assigned. [JSG]
uncategorized protein modification
A protein modification that is not chemically categorized.
PubMed:18688235
A protein modification that crosslinks two or more amino acid residues with covalent bonds.
XLNK-Res-Res
PSI-MOD
MOD:00033
The covalent bond is formed directly between sidechain atoms. If non-aminoacid atoms are involved in connecting two or more peptide chain residues peptide chain, the connection is classified as a multivalent binding site.
crosslinked residues
A protein modification that crosslinks two or more amino acid residues with covalent bonds.
PubMed:18688235
XLNK-Res-Res
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
-2.02
C 0 H -2 N 0 O 0 S 0
-2.01565
C 6 H 8 N 2 O 2 S 2
204.26
204.00272
C, C
natural
(2R,2'R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid)
3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid)
3,3'-dithiobis(2-aminopropanoic acid)
3,3'-dithiobisalanine
3,3'-dithiodialanine
Cys2
Cystine ((Cys)2)
DISULFID
DISULFID Interchain
L-cystine
XLNK-SCys-SCys
beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfide
beta,beta'-dithiodialanine
bis(alpha-aminopropionic acid)-beta-disulfide
bis(beta-amino-beta-carboxyethyl)disulfide
dicysteine
PSI-MOD
2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid
MOD:00034
Cross-link 2; for formation of a disulfide bond between a peptide cysteine and a free cysteine, see MOD:00765.
L-cystine (cross-link)
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
ChEBI:16283
DeltaMass:0
PubMed:1988019
PubMed:2001356
PubMed:2076469
PubMed:3083866
PubMed:366603
PubMed:7918467
PubMed:8344916
RESID:AA0025#CYS2
(2R,2'R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid)
3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid)
3,3'-dithiobis(2-aminopropanoic acid)
3,3'-dithiobisalanine
3,3'-dithiodialanine
Cys2
Cystine ((Cys)2)
DISULFID
DISULFID Interchain
L-cystine
XLNK-SCys-SCys
beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfide
beta,beta'-dithiodialanine
bis(alpha-aminopropionic acid)-beta-disulfide
bis(beta-amino-beta-carboxyethyl)disulfide
dicysteine
2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid
A protein modification that effectively converts an L-asparagine residue to (2S,3R)-3-hydroxyasparagine.
16.0
C 0 H 0 N 0 O 1
15.994915
C 4 H 6 N 2 O 3
130.1
130.03784
N
natural
uniprot.ptm:PTM-0369
(2S,3R)-2,4-diamino-3-hydroxy-4-oxobutanoic acid
(2S,3R)-2-amino-3-hydroxy-4-butanediamic acid
(2S,3R)-3-hydroxyasparagine
(3R)3HyAsn
2-azanyl-3-hydroxy-4-butanediamic acid
L-erythro-beta-hydroxyasparagine
MOD_RES (3R)-3-hydroxyasparagine
erythro-beta-hydroxylated L-asparagine
PSI-MOD
MOD:00035
(2S,3R)-3-hydroxyasparagine
A protein modification that effectively converts an L-asparagine residue to (2S,3R)-3-hydroxyasparagine.
ChEBI:141853
PubMed:11823643
PubMed:2820791
RESID:AA0026
(2S,3R)-2,4-diamino-3-hydroxy-4-oxobutanoic acid
(2S,3R)-2-amino-3-hydroxy-4-butanediamic acid
(2S,3R)-3-hydroxyasparagine
(3R)3HyAsn
2-azanyl-3-hydroxy-4-butanediamic acid
L-erythro-beta-hydroxyasparagine
MOD_RES (3R)-3-hydroxyasparagine
erythro-beta-hydroxylated L-asparagine
A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid.
16.0
C 0 H 0 N 0 O 1
15.994915
C 4 H 5 N 1 O 4
131.09
131.02185
D
natural
Unimod:35
uniprot.ptm:PTM-0371
(2S,3R)-2-amino-3-hydroxybutanedioic acid
(2S,3R)-3-hydroxyaspartic acid
(3R)3HyAsp
2-amino-3-hydroxysuccinic acid
2-azanyl-3-hydroxybutanedioic acid
3-hydroxyaspartic acid
L-erythro-beta-hydroxyaspartic acid
MOD_RES (3R)-3-hydroxyaspartate
erythro-beta-hydroxylated L-aspartic acid
hydroxylationd
PSI-MOD
Oxidation
MOD:00036
(2S,3R)-3-hydroxyaspartic acid
A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid.
ChEBI:141848
OMSSA:59
PubMed:6572939
PubMed:6871167
PubMed:8355279
RESID:AA0027
Unimod:35#D
(2S,3R)-2-amino-3-hydroxybutanedioic acid
(2S,3R)-3-hydroxyaspartic acid
(3R)3HyAsp
2-amino-3-hydroxysuccinic acid
2-azanyl-3-hydroxybutanedioic acid
3-hydroxyaspartic acid
L-erythro-beta-hydroxyaspartic acid
MOD_RES (3R)-3-hydroxyaspartate
erythro-beta-hydroxylated L-aspartic acid
hydroxylationd
Oxidation
A protein modification that effectively converts an L-lysine residue to one of the diastereomeric 5-hydroxy-L-lysine residues.
16.0
C 0 H 0 N 0 O 1
15.994915
C 6 H 12 N 2 O 2
144.17
144.08987
K
natural
uniprot.ptm:PTM-0044
5-hydroxylated L-lysine
5HyLys
PSI-MOD
MOD:00037
5-hydroxy-L-lysine
A protein modification that effectively converts an L-lysine residue to one of the diastereomeric 5-hydroxy-L-lysine residues.
ChEBI:60175
PubMed:18688235
5-hydroxylated L-lysine
5HyLys
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
16.0
C 0 H 0 N 0 O 1
15.994915
C 5 H 7 N 1 O 2
113.12
113.047676
P
natural
uniprot.ptm:PTM-0030
(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid
3-hydroxy-L-proline
3-hydroxylated L-proline
3-trans-hydroxy-L-proline
3HyPro
L-threo-3-hydroxyproline
MOD_RES 3-hydroxyproline
beta-hydroxypyrrolidine-alpha-carboxylic acid
PSI-MOD
MOD:00038
3-hydroxy-L-proline
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
ChEBI:16889
PubMed:2400108
PubMed:3734192
PubMed:4343807
RESID:AA0029
(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid
3-hydroxy-L-proline
3-hydroxylated L-proline
3-trans-hydroxy-L-proline
3HyPro
L-threo-3-hydroxyproline
MOD_RES 3-hydroxyproline
beta-hydroxypyrrolidine-alpha-carboxylic acid
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
16.0
C 0 H 0 N 0 O 1
15.994915
C 5 H 7 N 1 O 2
113.12
113.047676
P
natural
uniprot.ptm:PTM-0043
(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
4-hydroxy-L-proline
4-hydroxylated L-proline
4-hydroxyproline
4-trans-hydroxy-L-proline
4HyPro
L-threo-4-hydroxyproline
MOD_RES 4-hydroxyproline
gamma-hydroxypyrrolidine-alpha-carboxylic acid
PSI-MOD
MOD:00039
4-hydroxy-L-proline
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
ChEBI:18095
PubMed:11292863
PubMed:2400108
PubMed:3734192
RESID:AA0030
(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
4-hydroxy-L-proline
4-hydroxylated L-proline
4-hydroxyproline
4-trans-hydroxy-L-proline
4HyPro
L-threo-4-hydroxyproline
MOD_RES 4-hydroxyproline
gamma-hydroxypyrrolidine-alpha-carboxylic acid
A protein modification that effectively converts an L-glutamine residue to 2-pyrrolidone-5-carboxylic acid.
-17.03
C 0 H -3 N -1 O 0
-17.026548
C 5 H 6 N 1 O 2
112.11
112.039856
Q
natural
N-term
Unimod:28
uniprot.ptm:PTM-0261
(2S)-5-oxo-2-pyrrolidinecarboxylic acid
2-oxopyrrolidine-5-carboxylic acid
2-pyrrolidone-5-carboxylic acid
5-oxoproline
5-oxopyrrolidine-2-carboxylic acid
5-pyrrolidone-2-carboxylic acid
MOD_RES Pyrrolidone carboxylic acid
N-pyrrolidone carboxyl (N terminus)
PCA
PyrGlu(Gln)
Pyroglutamic Acid formed from Gln
Pyroglutamyl
ntermpeppyroq
pyroglutamic acid
PSI-MOD
Gln->pyro-Glu
Pyro-glu from Q
MOD:00040
DeltaMass gives a formula C 5 H 5 N 1 O 2 with mass 111.1
2-pyrrolidone-5-carboxylic acid (Gln)
A protein modification that effectively converts an L-glutamine residue to 2-pyrrolidone-5-carboxylic acid.
ChEBI:30652
DeltaMass:123
OMSSA:110
PubMed:10214721
PubMed:1836357
PubMed:26343
PubMed:3473473
RESID:AA0031#GLN
Unimod:28#Q
(2S)-5-oxo-2-pyrrolidinecarboxylic acid
2-oxopyrrolidine-5-carboxylic acid
2-pyrrolidone-5-carboxylic acid
5-oxoproline
5-oxopyrrolidine-2-carboxylic acid
5-pyrrolidone-2-carboxylic acid
MOD_RES Pyrrolidone carboxylic acid
N-pyrrolidone carboxyl (N terminus)
PCA
PyrGlu(Gln)
Pyroglutamic Acid formed from Gln
Pyroglutamyl
ntermpeppyroq
pyroglutamic acid
Gln->pyro-Glu
Pyro-glu from Q
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
44.01
C 1 H 0 N 0 O 2
43.98983
C 6 H 7 N 1 O 5
173.12
173.03242
E
natural
Unimod:299
uniprot.ptm:PTM-0039
(3S)-3-aminopropane-1,1,3-tricarboxylic acid
(3S)-3-azanylpropane-1,1,3-tricarboxylic acid
3-amino-1,1,3-propanetricarboxylic acid
3-azanylpropane-1,1,3-tricarboxylic acid
4-carboxyglutamic acid
4CbxGlu
Carboxy Glutamyl
L-gamma-carboxyglutamic acid
MOD_RES 4-carboxyglutamate
gamma-carboxylated L-glutamic acid
gammacarboxyle
PSI-MOD
1-carboxyglutamic acid
Carboxy
Carboxylation
MOD:00041
DeltaMass has an incorrect formula C 6 H 7 N 5 O 1 (N and O reversed) with mass 173.
L-gamma-carboxyglutamic acid
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
DeltaMass:217
OMSSA:48
PubMed:10517147
PubMed:1807167
PubMed:3263814
PubMed:4528109
PubMed:7457858
PubMed:8135347
PubMed:8868490
PubMed:9188685
RESID:AA0032
Unimod:299#E
(3S)-3-aminopropane-1,1,3-tricarboxylic acid
(3S)-3-azanylpropane-1,1,3-tricarboxylic acid
3-amino-1,1,3-propanetricarboxylic acid
3-azanylpropane-1,1,3-tricarboxylic acid
4-carboxyglutamic acid
4CbxGlu
Carboxy Glutamyl
L-gamma-carboxyglutamic acid
MOD_RES 4-carboxyglutamate
gamma-carboxylated L-glutamic acid
gammacarboxyle
1-carboxyglutamic acid
Carboxy
Carboxy
Carboxylation
A protein modification that effectively converts an L-aspartic acid residue to L-aspartic 4-phosphoric anhydride.
79.98
C 0 H 1 N 0 O 3 P 1
79.96633
C 4 H 6 N 1 O 6 P 1
195.07
194.99327
D
natural
Unimod:21
uniprot.ptm:PTM-0038
(2S)-2-amino-4-oxo-4-(phosphonooxy)butanoic acid
2-aminobutanedioic 4-phosphoric anhydride
2-azanyl-4-oxo-4-(phosphonooxy)butanoic acid
4-oxo-O-phosphono-L-homoserine
4-phosphoaspartic acid
4-phosphorylated L-aspartatic acid
ACT_SITE 4-aspartylphosphate intermediate
L-aspartic 4-phosphoric anhydride
MOD_RES 4-aspartylphosphate
PAsp
beta-aspartyl phosphate
PSI-MOD
Phospho
Phosphorylation
MOD:00042
L-aspartic 4-phosphoric anhydride
A protein modification that effectively converts an L-aspartic acid residue to L-aspartic 4-phosphoric anhydride.
ChEBI:15836
PubMed:4357737
RESID:AA0033
Unimod:21#D
(2S)-2-amino-4-oxo-4-(phosphonooxy)butanoic acid
2-aminobutanedioic 4-phosphoric anhydride
2-azanyl-4-oxo-4-(phosphonooxy)butanoic acid
4-oxo-O-phosphono-L-homoserine
4-phosphoaspartic acid
4-phosphorylated L-aspartatic acid
ACT_SITE 4-aspartylphosphate intermediate
L-aspartic 4-phosphoric anhydride
MOD_RES 4-aspartylphosphate
PAsp
beta-aspartyl phosphate
Phospho
Phosphorylation
A protein modification that effectively converts an L-cysteine residue to S-phospho-L-cysteine.
79.98
C 0 H 1 N 0 O 3 P 1 S 0
79.96633
C 3 H 6 N 1 O 4 P 1 S 1
183.12
182.97551
C
natural
Unimod:21
uniprot.ptm:PTM-0251
(2R)-2-amino-3-(phosphonosulfanyl)propanoic acid
2-azanyl-3-(phosphonosulfanyl)propanoic acid
ACT_SITE Phosphocysteine intermediate
MOD_RES Phosphocysteine
PCys
S-phospho-L-cysteine
S-phosphonocysteine
S-phosphorylated L-cysteine
S3-phosphocysteine
cysteine phosphate thioester
PSI-MOD
Phospho
Phosphorylation
MOD:00043
S-phospho-L-cysteine
A protein modification that effectively converts an L-cysteine residue to S-phospho-L-cysteine.
PubMed:3142516
PubMed:7961745
PubMed:8128219
RESID:AA0034
Unimod:21#C
(2R)-2-amino-3-(phosphonosulfanyl)propanoic acid
2-azanyl-3-(phosphonosulfanyl)propanoic acid
ACT_SITE Phosphocysteine intermediate
MOD_RES Phosphocysteine
PCys
S-phospho-L-cysteine
S-phosphonocysteine
S-phosphorylated L-cysteine
S3-phosphocysteine
cysteine phosphate thioester
Phospho
Phosphorylation
A protein modification that effectively converts an L-histidine residue to tele-phospho-L-histidine (N-tau-phospho-L-histidine, 1'-phospho-L-histidine).
79.98
C 0 H 1 N 0 O 3 P 1
79.96633
C 6 H 8 N 3 O 4 P 1
217.12
217.02524
H
natural
uniprot.ptm:PTM-0325
(2S)-2-amino-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid
1'-phospho-L-histidine
2-azanyl-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid
ACT_SITE Tele-phosphohistidine intermediate
MOD_RES Tele-phosphohistidine
N(tau)-phosphohistidine
N1-phosphonohistidine
NE2-phosphonohistidine
NtPHis
Ntau-phosphorylated L-histidine
histidine-N(epsilon)-phosphate
histidine-N1'-phosphate
tele-phosphohistidine
PSI-MOD
Phospho
Phosphorylation
histidine-3-phosphate
MOD:00044
1'-phospho-L-histidine
A protein modification that effectively converts an L-histidine residue to tele-phospho-L-histidine (N-tau-phospho-L-histidine, 1'-phospho-L-histidine).
PubMed:11038361
PubMed:5642389
PubMed:6692818
RESID:AA0035
(2S)-2-amino-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid
1'-phospho-L-histidine
2-azanyl-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid
ACT_SITE Tele-phosphohistidine intermediate
MOD_RES Tele-phosphohistidine
N(tau)-phosphohistidine
N1-phosphonohistidine
NE2-phosphonohistidine
NtPHis
Ntau-phosphorylated L-histidine
histidine-N(epsilon)-phosphate
histidine-N1'-phosphate
tele-phosphohistidine
Phospho
Phosphorylation
histidine-3-phosphate
A protein modification that effectively converts an L-histidine residue to pros-phospho-L-histidine (N-pi-phospho-L-histidine, 3'-phospho-L-histidine).
79.98
C 0 H 1 N 0 O 3 P 1
79.96633
C 6 H 8 N 3 O 4 P 1
217.12
217.02524
H
natural
uniprot.ptm:PTM-0260
(2S)-2-amino-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid
2-azanyl-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid
3'-phospho-L-histidine
ACT_SITE Pros-phosphohistidine intermediate
MOD_RES Pros-phosphohistidine
N(pi)-phosphohistidine
N3-phosphonohistidine
ND1-phosphonohistidine
NpPHis
Npi-phosphorylated L-histidine
histidine-N(delta)-phosphate
histidine-N3'-phosphate
pros-phosphohistidine
PSI-MOD
Phospho
Phosphorylation
histidine-1-phosphate
MOD:00045
3'-phospho-L-histidine
A protein modification that effectively converts an L-histidine residue to pros-phospho-L-histidine (N-pi-phospho-L-histidine, 3'-phospho-L-histidine).
PubMed:1549615
PubMed:5642389
PubMed:6692818
PubMed:7669763
PubMed:7803390
RESID:AA0036
(2S)-2-amino-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid
2-azanyl-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid
3'-phospho-L-histidine
ACT_SITE Pros-phosphohistidine intermediate
MOD_RES Pros-phosphohistidine
N(pi)-phosphohistidine
N3-phosphonohistidine
ND1-phosphonohistidine
NpPHis
Npi-phosphorylated L-histidine
histidine-N(delta)-phosphate
histidine-N3'-phosphate
pros-phosphohistidine
Phospho
Phosphorylation
histidine-1-phosphate
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
79.98
C 0 H 1 N 0 O 3 P 1
79.96633
C 3 H 6 N 1 O 5 P 1
167.06
166.99835
S
natural
Unimod:21
uniprot.ptm:PTM-0253
(2S)-2-amino-3-(phosphonooxy)propanoic acid
2-amino-3-hydroxypropanoic acid 3-phosphate
2-azanyl-3-(phosphonooxy)propanoic acid
ACT_SITE Phosphoserine intermediate
MOD_RES Phosphoserine
O-phospho-L-serine
O-phosphonoserine
O-phosphorylated L-serine
O3-phosphoserine
OPSer
Phospho Seryl
phosphorylations
serine phosphate ester
PSI-MOD
Phospho
Phosphorylation
MOD:00046
O-phospho-L-serine
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
ChEBI:15811
DeltaMass:0
OMSSA:6
PubMed:12923550
PubMed:4065410
PubMed:8061611
RESID:AA0037
Unimod:21#S
(2S)-2-amino-3-(phosphonooxy)propanoic acid
2-amino-3-hydroxypropanoic acid 3-phosphate
2-azanyl-3-(phosphonooxy)propanoic acid
ACT_SITE Phosphoserine intermediate
MOD_RES Phosphoserine
O-phospho-L-serine
O-phosphonoserine
O-phosphorylated L-serine
O3-phosphoserine
OPSer
Phospho Seryl
phosphorylations
serine phosphate ester
Phospho
Phosphorylation
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
79.98
C 0 H 1 N 0 O 3 P 1
79.96633
C 4 H 8 N 1 O 5 P 1
181.08
181.014
T
natural
Unimod:21
uniprot.ptm:PTM-0254
(2S,3R)-2-amino-3-(phosphonooxy)butanoic acid
2-amino-3-hydroxybutanoic acid 3-phosphate
2-azanyl-3-(phosphonooxy)butanoic acid
MOD_RES Phosphothreonine
O-phospho-L-threonine
O-phosphorylated L-threonine
O3-phosphothreonine
OPThr
Phospho Threonyl
phosphorylationt
threonine phosphate ester
PSI-MOD
Phospho
Phosphorylation
MOD:00047
O-phospho-L-threonine
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
ChEBI:21967
DeltaMass:0
OMSSA:7
PubMed:12923550
PubMed:7678926
RESID:AA0038
Unimod:21#T
(2S,3R)-2-amino-3-(phosphonooxy)butanoic acid
2-amino-3-hydroxybutanoic acid 3-phosphate
2-azanyl-3-(phosphonooxy)butanoic acid
MOD_RES Phosphothreonine
O-phospho-L-threonine
O-phosphorylated L-threonine
O3-phosphothreonine
OPThr
Phospho Threonyl
phosphorylationt
threonine phosphate ester
Phospho
Phosphorylation
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
79.98
C 0 H 1 N 0 O 3 P 1
79.96633
C 9 H 10 N 1 O 5 P 1
243.15
243.02966
Y
natural
Unimod:21
uniprot.ptm:PTM-0255
(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid
2-amino-3-(4-hydroxyphenyl)propanoic acid 4'-phosphate
2-azanyl-3-(4-phosphonooxyphenyl)propanoic acid
MOD_RES Phosphotyrosine
O4'-phospho-L-tyrosine
O4'-phosphorylated L-tyrosine
O4-phosphotyrosine
OPTyr
Phospho Tyrosinyl
phosphorylationy
tyrosine phosphate
PSI-MOD
Phospho
Phosphorylation
MOD:00048
O4'-phospho-L-tyrosine
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
DeltaMass:0
OMSSA:8
PubMed:10226369
PubMed:1725475
RESID:AA0039
Unimod:21#Y
(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid
2-amino-3-(4-hydroxyphenyl)propanoic acid 4'-phosphate
2-azanyl-3-(4-phosphonooxyphenyl)propanoic acid
MOD_RES Phosphotyrosine
O4'-phospho-L-tyrosine
O4'-phosphorylated L-tyrosine
O4-phosphotyrosine
OPTyr
Phospho Tyrosinyl
phosphorylationy
tyrosine phosphate
Phospho
Phosphorylation
A protein modification that effectively converts an L-histidine residue to diphthamide.
143.21
C 7 H 15 N 2 O 1
143.11789
1+
C 13 H 22 N 5 O 2
280.35
280.1768
H
natural
Unimod:375
uniprot.ptm:PTM-0118
(2R)-1-amino-4-(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-aminium
(3-[4-(2-amino-2-carboxy-ethyl)-1H-imidazol-2-yl]-1-carbamoyl-propyl)-trimethylammonium
1-azanyl-4-(4-[2-azanyl-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-azanium
2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine
2-[(R)-3-carboxamido-3-(trimethylammonio)propyl]-4-((S)-2-amino-2-carboxyethyl)-1H-imidazole
2-[3-carboxamido-3-(trimethylammonio)propyl]histidine
2-amino-3-[[2-(3-amino-3-carbamoyl-prop-1-enyl)-1,1,3-trimethyl-2,3-dihydroimidazol-5-yl]]propanoic acid
2-amino-4-[[5-(2-amino-2-carboxylato-ethyl)-1,1,3-trimethyl-2,3-dihydroimidazol-2-yl]]but-3-enamide
Diphth
MOD_RES Diphthamide
alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-1H-imidazole-2-propanaminium
diphthamide
diphthamide (from histidine)
PSI-MOD
Diphthamide
MOD:00049
2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine
A protein modification that effectively converts an L-histidine residue to diphthamide.
ChEBI:16692
DeltaMass:122
PubMed:15316019
PubMed:7430147
RESID:AA0040
Unimod:375#H
(2R)-1-amino-4-(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-aminium
(3-[4-(2-amino-2-carboxy-ethyl)-1H-imidazol-2-yl]-1-carbamoyl-propyl)-trimethylammonium
1-azanyl-4-(4-[2-azanyl-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-azanium
2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine
2-[(R)-3-carboxamido-3-(trimethylammonio)propyl]-4-((S)-2-amino-2-carboxyethyl)-1H-imidazole
2-[3-carboxamido-3-(trimethylammonio)propyl]histidine
2-amino-3-[[2-(3-amino-3-carbamoyl-prop-1-enyl)-1,1,3-trimethyl-2,3-dihydroimidazol-5-yl]]propanoic acid
2-amino-4-[[5-(2-amino-2-carboxylato-ethyl)-1,1,3-trimethyl-2,3-dihydroimidazol-2-yl]]but-3-enamide
Diphth
MOD_RES Diphthamide
alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-1H-imidazole-2-propanaminium
diphthamide
diphthamide (from histidine)
Diphthamide
Diphthamide
A protein modification that effectively converts an L-alanine residue to N-acetyl-L-alanine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 5 H 8 N 1 O 2
114.12
114.055504
A
natural
N-term
uniprot.ptm:PTM-0199
(2S)-2-(acetamido)propanoic acid
2-(acetylamino)propanoic acid
2-(acetylazanyl)propanoic acid
AcAla
MOD_RES N-acetylalanine
N-acetyl-L-alanine
N-acetylated L-alanine
acetylalanine
PSI-MOD
MOD:00050
N-acetyl-L-alanine
A protein modification that effectively converts an L-alanine residue to N-acetyl-L-alanine.
PubMed:363452
PubMed:4700463
RESID:AA0041
(2S)-2-(acetamido)propanoic acid
2-(acetylamino)propanoic acid
2-(acetylazanyl)propanoic acid
AcAla
MOD_RES N-acetylalanine
N-acetyl-L-alanine
N-acetylated L-alanine
acetylalanine
A protein modification that effectively converts an L-aspartic acid residue to N-acetyl-L-aspartic acid.
42.04
C 2 H 2 N 0 O 1
42.010567
C 6 H 8 N 1 O 4
158.13
158.04533
D
natural
N-term
uniprot.ptm:PTM-0200
(2S)-2-(acetamido)butanedioic acid
2-(acetylamino)butanedioic acid
2-(acetylazanyl)butanedioic acid
AcAsp
MOD_RES N-acetylaspartate
N-acetyl-L-aspartic acid
N-acetylated L-aspartic acid
acetylaspartic acid
PSI-MOD
MOD:00051
N-acetyl-L-aspartic acid
A protein modification that effectively converts an L-aspartic acid residue to N-acetyl-L-aspartic acid.
ChEBI:21547
PubMed:1560020
PubMed:2395459
RESID:AA0042
(2S)-2-(acetamido)butanedioic acid
2-(acetylamino)butanedioic acid
2-(acetylazanyl)butanedioic acid
AcAsp
MOD_RES N-acetylaspartate
N-acetyl-L-aspartic acid
N-acetylated L-aspartic acid
acetylaspartic acid
A protein modification that effectively converts an L-cysteine residue to N-acetyl-L-cysteine.
42.04
C 2 H 2 N 0 O 1 S 0
42.010567
C 5 H 8 N 1 O 2 S 1
146.18
146.02757
C
natural
N-term
uniprot.ptm:PTM-0201
(2R)-2-acetamido-3-sulfanylpropanoic acid
2-acetylamino-3-mercaptopropanoic acid
2-acetylamino-3-sulfanylpropanoic acid
2-acetylazanyl-3-sulfanylpropanoic acid
MOD_RES N-acetylcysteine
N-acetyl-L-cysteine
N-acetylated cysteine
N-acetylcysteine
NAcCys
PSI-MOD
Acetyl
MOD:00052
incidental to RESID:AA0223
N-acetyl-L-cysteine
A protein modification that effectively converts an L-cysteine residue to N-acetyl-L-cysteine.
ChEBI:28939
PubMed:11857757
PubMed:11999733
PubMed:12175151
PubMed:14730666
PubMed:1500421
PubMed:15350136
PubMed:6725286
RESID:AA0043
(2R)-2-acetamido-3-sulfanylpropanoic acid
2-acetylamino-3-mercaptopropanoic acid
2-acetylamino-3-sulfanylpropanoic acid
2-acetylazanyl-3-sulfanylpropanoic acid
MOD_RES N-acetylcysteine
N-acetyl-L-cysteine
N-acetylated cysteine
N-acetylcysteine
NAcCys
Acetyl
A protein modification that effectively converts an L-glutamic acid residue to N-acetyl-L-glutamic acid.
42.04
C 2 H 2 N 0 O 1
42.010567
C 7 H 10 N 1 O 4
172.16
172.06099
E
natural
N-term
uniprot.ptm:PTM-0202
(2S)-2-(acetamido)pentanedioic acid
2-(acetylamino)pentanedioic acid
2-(acetylazanyl)pentanedioic acid
AcGlu
MOD_RES N-acetylglutamate
N-acetyl-L-glutamic acid
N-acetylated L-glutamic acid
acetylglutamic acid
PSI-MOD
MOD:00053
N-acetyl-L-glutamic acid
A protein modification that effectively converts an L-glutamic acid residue to N-acetyl-L-glutamic acid.
ChEBI:17533
PubMed:6725286
RESID:AA0044
(2S)-2-(acetamido)pentanedioic acid
2-(acetylamino)pentanedioic acid
2-(acetylazanyl)pentanedioic acid
AcGlu
MOD_RES N-acetylglutamate
N-acetyl-L-glutamic acid
N-acetylated L-glutamic acid
acetylglutamic acid
A protein modification that effectively converts an L-glutamine residue to N-acetyl-L-glutamine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 7 H 11 N 2 O 3
171.18
171.07697
Q
artifact
N-term
(2S)-2-acetamido-5-pentanediamic acid
2-acetylamino-5-amino-5-oxopentanoic acid
2-acetylamino-5-pentanediamic acid
2-acetylazanyl-5-azanyl-5-oxopentanoic acid
AcGln
N-acetyl-L-glutamine
N-acetylated L-glutamine
acetylglutamine
PSI-MOD
MOD:00054
This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
N-acetyl-L-glutamine
A protein modification that effectively converts an L-glutamine residue to N-acetyl-L-glutamine.
RESID:AA0045
(2S)-2-acetamido-5-pentanediamic acid
2-acetylamino-5-amino-5-oxopentanoic acid
2-acetylamino-5-pentanediamic acid
2-acetylazanyl-5-azanyl-5-oxopentanoic acid
AcGln
N-acetyl-L-glutamine
N-acetylated L-glutamine
acetylglutamine
A protein modification that effectively converts a glycine residue to N-acetylglycine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 4 H 6 N 1 O 2
100.1
100.039856
G
natural
N-term
uniprot.ptm:PTM-0203
(acetylamino)acetic acid
(acetylazanyl)ethanoic acid
2-(acetamido)ethanoic acid
2-(acetylamino)ethanoic acid
AcGly
MOD_RES N-acetylglycine
N-acetylated glycine
N-acetylglycine
aceturic acid
PSI-MOD
MOD:00055
N-acetylglycine
A protein modification that effectively converts a glycine residue to N-acetylglycine.
PubMed:272676
PubMed:5545094
PubMed:6754709
RESID:AA0046
(acetylamino)acetic acid
(acetylazanyl)ethanoic acid
2-(acetamido)ethanoic acid
2-(acetylamino)ethanoic acid
AcGly
MOD_RES N-acetylglycine
N-acetylated glycine
N-acetylglycine
aceturic acid
A protein modification that effectively converts an L-isoleucine residue to N-acetyl-L-isoleucine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 8 H 14 N 1 O 2
156.2
156.10245
I
artifact
N-term
uniprot.ptm:PTM-0204
(2S,3S)-2-acetamido-3-methylpentanoic acid
2-acetylamino-3-methylpentanoic acid
2-acetylazanyl-3-methylpentanoic acid
AcIle
N-acetyl-L-isoleucine
N-acetylated L-isoleucine
acetylisoleucine
PSI-MOD
MOD:00056
This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
N-acetyl-L-isoleucine
A protein modification that effectively converts an L-isoleucine residue to N-acetyl-L-isoleucine.
PubMed:8034631
RESID:AA0047
(2S,3S)-2-acetamido-3-methylpentanoic acid
2-acetylamino-3-methylpentanoic acid
2-acetylazanyl-3-methylpentanoic acid
AcIle
N-acetyl-L-isoleucine
N-acetylated L-isoleucine
acetylisoleucine
A protein modification that effectively converts an L-lysine residue to N2-acetyl-L-lysine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 8 H 15 N 2 O 2
171.22
171.11336
K
artifact
N-term
(2S)-2-acetamido-6-aminohexanoic acid
2-acetylamino-6-aminohexanoic acid
2-acetylazanyl-6-azanylhexanoic acid
N2-acetyl-L-lysine
N2-acetylated L-lysine
N2-acetyllysine
N2AcLys
PSI-MOD
Acetyl
MOD:00057
This is a deprecated entry in RESID. It probably does not occur naturally [JSG].
N2-acetyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N2-acetyl-L-lysine.
PubMed:11857757
PubMed:11999733
PubMed:12175151
PubMed:14730666
PubMed:15350136
RESID:AA0048
(2S)-2-acetamido-6-aminohexanoic acid
2-acetylamino-6-aminohexanoic acid
2-acetylazanyl-6-azanylhexanoic acid
N2-acetyl-L-lysine
N2-acetylated L-lysine
N2-acetyllysine
N2AcLys
Acetyl
A protein modification that effectively converts an L-methionine to N-acetyl-L-methionine.
42.04
C 2 H 2 N 0 O 1 S 0
42.010567
C 7 H 12 N 1 O 2 S 1
174.24
174.05887
M
natural
N-term
uniprot.ptm:PTM-0205
(2S)-2-acetamido-4-(methylsulfanyl)butanoic acid
2-acetylamino-4-(methylsulfanyl)butanoic acid
2-acetylamino-4-(methylthio)butanoic acid
2-acetylazanyl-4-(methylsulfanyl)butanoic acid
AcMet
MOD_RES N-acetylmethionine
N-acetyl-L-methionine
N-acetylated L-methionine
acetylmethionine
methionamine
PSI-MOD
MOD:00058
N-acetyl-L-methionine
A protein modification that effectively converts an L-methionine to N-acetyl-L-methionine.
PubMed:7944406
RESID:AA0049
(2S)-2-acetamido-4-(methylsulfanyl)butanoic acid
2-acetylamino-4-(methylsulfanyl)butanoic acid
2-acetylamino-4-(methylthio)butanoic acid
2-acetylazanyl-4-(methylsulfanyl)butanoic acid
AcMet
MOD_RES N-acetylmethionine
N-acetyl-L-methionine
N-acetylated L-methionine
acetylmethionine
methionamine
A protein modification that effectively converts an L-proline residue to N-acetyl-L-proline.
42.04
C 2 H 2 N 0 O 1
42.010567
C 7 H 10 N 1 O 2
140.16
140.07115
P
natural
N-term
uniprot.ptm:PTM-0206
(2S)-1-acetyl-2-pyrrolidinecarboxylic acid
1-acetylproline
MOD_RES N-acetylproline
N-acetyl-L-proline
N-acetylated L-proline
N-acetylproline
NAcPro
acetylproline
PSI-MOD
MOD:00059
N-acetyl-L-proline
A protein modification that effectively converts an L-proline residue to N-acetyl-L-proline.
PubMed:2928307
RESID:AA0050
(2S)-1-acetyl-2-pyrrolidinecarboxylic acid
1-acetylproline
MOD_RES N-acetylproline
N-acetyl-L-proline
N-acetylated L-proline
N-acetylproline
NAcPro
acetylproline
A protein modification that effectively converts an L-serine residue to N-acetyl-L-serine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 5 H 8 N 1 O 3
130.12
130.05042
S
natural
N-term
uniprot.ptm:PTM-0207
(2S)-2-acetamido-3-hydroxypropanoic acid
2-acetylamino-3-hydroxypropanoic acid
2-acetylazanyl-3-hydroxypropanoic acid
MOD_RES N-acetylserine
N-acetyl-L-serine
N-acetylated L-serine
N-acetylserine
NAcSer
PSI-MOD
Acetyl
MOD:00060
N-acetyl-L-serine
A protein modification that effectively converts an L-serine residue to N-acetyl-L-serine.
PubMed:11857757
PubMed:11999733
PubMed:12175151
PubMed:14730666
PubMed:15350136
PubMed:1880797
PubMed:2106685
PubMed:6997045
RESID:AA0051
(2S)-2-acetamido-3-hydroxypropanoic acid
2-acetylamino-3-hydroxypropanoic acid
2-acetylazanyl-3-hydroxypropanoic acid
MOD_RES N-acetylserine
N-acetyl-L-serine
N-acetylated L-serine
N-acetylserine
NAcSer
Acetyl
A protein modification that effectively converts an L-threonine residue to N-acetyl-L-threonine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 6 H 10 N 1 O 3
144.15
144.06607
T
natural
N-term
uniprot.ptm:PTM-0208
(2S,3R)-2-acetamido-3-hydroxybutanoic acid
2-acetylamino-3-hydroxybutanoic acid
2-acetylazanyl-3-hydroxybutanoic acid
MOD_RES N-acetylthreonine
N-acetyl-L-threonine
N-acetylated L-threonine
N-acetylthreonine
N-methylcarbonylthreonine
NAcThr
PSI-MOD
Acetyl
Acetylation
MOD:00061
N-acetyl-L-threonine
A protein modification that effectively converts an L-threonine residue to N-acetyl-L-threonine.
PubMed:11857757
PubMed:11999733
PubMed:12175151
PubMed:14730666
PubMed:15350136
PubMed:2106685
PubMed:6997045
RESID:AA0052
(2S,3R)-2-acetamido-3-hydroxybutanoic acid
2-acetylamino-3-hydroxybutanoic acid
2-acetylazanyl-3-hydroxybutanoic acid
MOD_RES N-acetylthreonine
N-acetyl-L-threonine
N-acetylated L-threonine
N-acetylthreonine
N-methylcarbonylthreonine
NAcThr
Acetyl
Acetylation
A protein modification that effectively converts an L-tyrosine residue to N-acetyl-L-tyrosine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 11 H 12 N 1 O 3
206.22
206.08171
Y
natural
N-term
uniprot.ptm:PTM-0209
(2S)-2-acetamido-3-(4-hydoxyphenyl)propanoic acid
2-acetylamino-3-(4-hydoxyphenyl)propanoic acid
2-acetylazanyl-3-(4-hydoxyphenyl)propanoic acid
AcTyr
MOD_RES N-acetyltyrosine
N-acetyl-L-tyrosine
N-acetylated L-tyrosine
N-acetyltyrosine
PSI-MOD
Acetyl
MOD:00062
N-acetyl-L-tyrosine
A protein modification that effectively converts an L-tyrosine residue to N-acetyl-L-tyrosine.
PubMed:11857757
PubMed:11999733
PubMed:12175151
PubMed:14730666
PubMed:15350136
PubMed:2506074
PubMed:475783
RESID:AA0053
(2S)-2-acetamido-3-(4-hydoxyphenyl)propanoic acid
2-acetylamino-3-(4-hydoxyphenyl)propanoic acid
2-acetylazanyl-3-(4-hydoxyphenyl)propanoic acid
AcTyr
MOD_RES N-acetyltyrosine
N-acetyl-L-tyrosine
N-acetylated L-tyrosine
N-acetyltyrosine
Acetyl
A protein modification that effectively converts an L-valine residue to N-acetyl-L-valine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 7 H 12 N 1 O 2
142.18
142.0868
V
natural
N-term
uniprot.ptm:PTM-0210
(2S)-2-acetamido-3-methylbutanoic acid
2-acetylamino-3-methylbutanoic acid
2-acetylazanyl-3-methylbutanoic acid
AcVal
MOD_RES N-acetylvaline
N-acetyl-L-valine
N-acetylated L-valine
N-acetylvaline
PSI-MOD
MOD:00063
N-acetyl-L-valine
A protein modification that effectively converts an L-valine residue to N-acetyl-L-valine.
PubMed:1735421
RESID:AA0054
(2S)-2-acetamido-3-methylbutanoic acid
2-acetylamino-3-methylbutanoic acid
2-acetylazanyl-3-methylbutanoic acid
AcVal
MOD_RES N-acetylvaline
N-acetyl-L-valine
N-acetylated L-valine
N-acetylvaline
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
42.04
C 2 H 2 N 0 O 1
42.010567
C 8 H 14 N 2 O 2
170.21
170.10553
K
natural
Unimod:1
uniprot.ptm:PTM-0190
(2S)-6-acetamido-2-aminohexanoic acid
6-acetylamino-2-aminohexanoic acid
6-acetylazanyl-2-aminohexanoic acid
MOD_RES N6-acetyllysine
N(zeta)-acetyllysine
N6-acetyl-L-lysine
N6-acetylated L-lysine
N6AcLys
acetylk
epsilon-acetyllysine
PSI-MOD
Acetyl
Acetylation
MOD:00064
N6-acetyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
ChEBI:17752
DeltaMass:214
OMSSA:24
PubMed:11369851
PubMed:11857757
PubMed:11999733
PubMed:12175151
PubMed:14730666
PubMed:15350136
PubMed:1680872
PubMed:670159
RESID:AA0055
Unimod:1#K
(2S)-6-acetamido-2-aminohexanoic acid
6-acetylamino-2-aminohexanoic acid
6-acetylazanyl-2-aminohexanoic acid
MOD_RES N6-acetyllysine
N(zeta)-acetyllysine
N6-acetyl-L-lysine
N6-acetylated L-lysine
N6AcLys
acetylk
epsilon-acetyllysine
Acetyl
Acetylation
A protein modification that effectively converts an L-cysteine residue to S-acetyl-L-cysteine.
42.04
C 2 H 2 N 0 O 1 S 0
42.010567
C 5 H 7 N 1 O 2 S 1
145.18
145.01974
C
natural
Unimod:1
(2R)-3-acetylsulfanyl-2-aminopropanoic acid
2-amino-3-(acetylthio)propanoic acid
2-azanyl-3-(acetylsulfanyl)propanoic acid
ACT_SITE S-acetylcysteine intermediate
S-acetyl-L-cysteine
S-acetylcysteine
SAcCys
cysteine acetate thioester
PSI-MOD
Acetyl
Acetylation
MOD:00065
S-acetyl-L-cysteine
A protein modification that effectively converts an L-cysteine residue to S-acetyl-L-cysteine.
PubMed:11857757
PubMed:11999733
PubMed:12175151
PubMed:1310545
PubMed:14730666
PubMed:15350136
RESID:AA0056
Unimod:1#C
(2R)-3-acetylsulfanyl-2-aminopropanoic acid
2-amino-3-(acetylthio)propanoic acid
2-azanyl-3-(acetylsulfanyl)propanoic acid
ACT_SITE S-acetylcysteine intermediate
S-acetyl-L-cysteine
S-acetylcysteine
SAcCys
cysteine acetate thioester
Acetyl
Acetylation
A protein modification that effectively converts a glycine residue to N-formylglycine.
28.01
C 1 H 0 N 0 O 1
27.994915
C 3 H 4 N 1 O 2
86.07
86.0242
G
natural
N-term
uniprot.ptm:PTM-0211
(formylamino)acetic acid
(formylamino)ethanoic acid
(formylazanyl)ethanoic acid
2-formamidoacetic acid
2-formamidoethanoic acid
MOD_RES N-formylglycine
N(alpha)-formylglycine
N-formylated glycine
N-formylglycine
NFoGly
PSI-MOD
MOD:00066
N-formylglycine
A protein modification that effectively converts a glycine residue to N-formylglycine.
PubMed:5139483
RESID:AA0057
(formylamino)acetic acid
(formylamino)ethanoic acid
(formylazanyl)ethanoic acid
2-formamidoacetic acid
2-formamidoethanoic acid
MOD_RES N-formylglycine
N(alpha)-formylglycine
N-formylated glycine
N-formylglycine
NFoGly
A protein modification that effectively converts a glycine residue to N-D-glucuronoylglycine.
176.12
C 6 H 8 N 0 O 6
176.03209
C 8 H 12 N 1 O 7
234.18
234.06137
G
natural
N-term
uniprot.ptm:PTM-0331
2-(glucuronoylamino)ethanoic acid
MOD_RES N-D-glucuronoyl glycine
N-D-glucuronoyl-glycine
N-D-glucuronyl-glycine
NGlcAGly
ntermpepglucuronylg
PSI-MOD
Glucuronyl
MOD:00067
N-D-glucuronoylglycine
A protein modification that effectively converts a glycine residue to N-D-glucuronoylglycine.
OMSSA:50
PubMed:10858503
PubMed:12716131
PubMed:6493057
PubMed:7398618
RESID:AA0058
2-(glucuronoylamino)ethanoic acid
MOD_RES N-D-glucuronoyl glycine
N-D-glucuronoyl-glycine
N-D-glucuronyl-glycine
NGlcAGly
ntermpepglucuronylg
Glucuronyl
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
210.36
C 14 H 26 N 0 O 1
210.19836
C 16 H 30 N 1 O 2
268.42
268.22766
G
natural
N-term
Unimod:45
uniprot.ptm:PTM-0221
(tetradecanoylamino)ethanoic acid
LIPID N-myristoyl glycine
N-(1-oxotetradecyl)glycine
N-(C14:0 aliphatic acyl)glycine
N-myristoyl-glycine
N-myristoylated glycine
N-myristylglycine
N-tetradecanoylglycine
NMyrGly
ntermpepmyristoylationg
PSI-MOD
Myristoyl
Myristoylation
MOD:00068
N-myristoylglycine
A protein modification that effectively converts a glycine residue to N-myristoylglycine.
OMSSA:80
PubMed:11955007
PubMed:11955008
PubMed:1326520
PubMed:1386601
PubMed:6436247
PubMed:7543369
RESID:AA0059
Unimod:45#G
(tetradecanoylamino)ethanoic acid
LIPID N-myristoyl glycine
N-(1-oxotetradecyl)glycine
N-(C14:0 aliphatic acyl)glycine
N-myristoyl-glycine
N-myristoylated glycine
N-myristylglycine
N-tetradecanoylglycine
NMyrGly
ntermpepmyristoylationg
Myristoyl
Myristoylation
A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine.
238.41
C 16 H 30 N 0 O 1 S 0
238.22966
C 19 H 36 N 1 O 2 S 1
342.56
342.24667
C
natural
N-term
uniprot.ptm:PTM-0222
(2R)-2-hexadecanoylamino-3-sulfanylpropanoic acid
2-hexadecanamido-3-sulfanylpropanoic acid
2-hexadecanoylamino-3-mercaptopropanoic acid
LIPID N-palmitoyl cysteine
N-(1-oxahexadecyl)-L-cysteine
N-hexadecanoylated L-cysteine
N-palmitoyl-L-cysteine
N-palmitoylated L-cysteine
NPamCys
PSI-MOD
Palmitoyl
Palmitoylation
MOD:00069
incidental to RESID:AA0107 incidental to RESID:AA0309
N-palmitoyl-L-cysteine
A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine.
PubMed:10896212
PubMed:4575979
PubMed:9056182
PubMed:9593755
RESID:AA0060
(2R)-2-hexadecanoylamino-3-sulfanylpropanoic acid
2-hexadecanamido-3-sulfanylpropanoic acid
2-hexadecanoylamino-3-mercaptopropanoic acid
LIPID N-palmitoyl cysteine
N-(1-oxahexadecyl)-L-cysteine
N-hexadecanoylated L-cysteine
N-palmitoyl-L-cysteine
N-palmitoylated L-cysteine
NPamCys
Palmitoyl
Palmitoylation
A protein modification that effectively converts an L-alanine residue to N-methyl-L-alanine.
14.03
C 1 H 2 N 0 O 0
14.01565
C 4 H 7 N 1 O 1
85.11
85.052765
A
natural
N-term
uniprot.ptm:PTM-0214
(2S)-2-methylaminopropanoic acid
2-methylazanylpropanoic acid
MOD_RES N-methylalanine
N-methyl-L-alanine
N-methylalanine
N-methylated L-alanine
NMe1Ala
PSI-MOD
Methyl
Methylation
MOD:00070
Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
N-methyl-L-alanine
A protein modification that effectively converts an L-alanine residue to N-methyl-L-alanine.
ChEBI:17519
PubMed:323502
PubMed:337304
PubMed:7007074
RESID:AA0061
(2S)-2-methylaminopropanoic acid
2-methylazanylpropanoic acid
MOD_RES N-methylalanine
N-methyl-L-alanine
N-methylalanine
N-methylated L-alanine
NMe1Ala
Methyl
Methylation
A protein modification that effectively converts an L-alanine residue to N,N,N-trimethyl-L-alanine.
43.09
C 3 H 7 N 0 O 0
43.054226
1+
C 6 H 13 N 1 O 1
115.18
115.09917
A
natural
N-term
uniprot.ptm:PTM-0177
(1S)-1-carboxy-N,N,N-trimethylethanaminium
(1S)-1-carboxy-N,N,N-trimethylethanazanium
(2S)-2-(trimethylammonio)propanoic acid
MOD_RES N,N,N-trimethylalanine
N,N,N-trimethyl-L-alanine
N,N,N-trimethylalanine cation
N,N,N-trimethylalaninium
N,N,N-trimethylated L-alanine
N2Me3+Ala
NMe3Ala
PSI-MOD
Trimethyl
tri-Methylation
MOD:00071
N,N,N-trimethyl-L-alanine
A protein modification that effectively converts an L-alanine residue to N,N,N-trimethyl-L-alanine.
PubMed:12590383
PubMed:332162
PubMed:3979397
PubMed:6778808
PubMed:7715456
RESID:AA0062
(1S)-1-carboxy-N,N,N-trimethylethanaminium
(1S)-1-carboxy-N,N,N-trimethylethanazanium
(2S)-2-(trimethylammonio)propanoic acid
MOD_RES N,N,N-trimethylalanine
N,N,N-trimethyl-L-alanine
N,N,N-trimethylalanine cation
N,N,N-trimethylalaninium
N,N,N-trimethylated L-alanine
N2Me3+Ala
NMe3Ala
Trimethyl
tri-Methylation
A protein modification that effectively converts a glycine residue to N-methylglycine.
14.03
C 1 H 2 N 0 O 0
14.01565
C 3 H 5 N 1 O 1
71.08
71.03712
G
natural
N-term
uniprot.ptm:PTM-0483
L-sarcosine
MOD_RES N-methylglycine
N-methylated glycine
N-methylglycine
NMe1Gly
Sar
Sarcosine
Sarcosyl
methylaminoacetic acid
methylaminoethanoic acid
PSI-MOD
Methyl
Methylation
MOD:00072
DeltaMass also has an entry for the free amino acid. Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
N-methylglycine
A protein modification that effectively converts a glycine residue to N-methylglycine.
ChEBI:15611
DeltaMass:0
PubMed:1593629
RESID:AA0063
L-sarcosine
MOD_RES N-methylglycine
N-methylated glycine
N-methylglycine
NMe1Gly
Sar
Sarcosine
Sarcosyl
methylaminoacetic acid
methylaminoethanoic acid
Methyl
Methylation
A protein modification that effectively converts an L-methionine residue to N-methyl-L-methionine.
14.03
C 1 H 2 N 0 O 0 S 0
14.01565
C 6 H 11 N 1 O 1 S 1
145.22
145.05614
M
natural
N-term
uniprot.ptm:PTM-0217
(2S)-2-methylamino-4-(methylsulfanyl)butanoic acid
2-methylamino-4-(methylthio)butanoic acid
MOD_RES N-methylmethionine
Methyl Methionyl
N-methyl-L-methionine
N-methylated L-methionine
N-methylmethionine
NMe1Met
PSI-MOD
Methyl
Methylation
MOD:00073
Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
N-methyl-L-methionine
A protein modification that effectively converts an L-methionine residue to N-methyl-L-methionine.
DeltaMass:169
PubMed:323502
PubMed:3298225
RESID:AA0064
(2S)-2-methylamino-4-(methylsulfanyl)butanoic acid
2-methylamino-4-(methylthio)butanoic acid
MOD_RES N-methylmethionine
Methyl Methionyl
N-methyl-L-methionine
N-methylated L-methionine
N-methylmethionine
NMe1Met
Methyl
Methylation
A protein modification that effectively converts an L-phenylalanine residue to N-methyl-L-phenylalanine.
14.03
C 1 H 2 N 0 O 0
14.01565
C 10 H 11 N 1 O 1
161.2
161.08406
F
natural
N-term
uniprot.ptm:PTM-0218
(2S)-2-methylamino-3-phenylpropanoic acid
MOD_RES N-methylphenylalanine
N-methyl-L-phenylalanine
N-methylated L-phenylalanine
N-methylphenylalanine
NMe1Phe
PSI-MOD
Methyl
Methylation
MOD:00074
Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG].
N-methyl-L-phenylalanine
A protein modification that effectively converts an L-phenylalanine residue to N-methyl-L-phenylalanine.
PubMed:2577730
PubMed:413571
RESID:AA0065
(2S)-2-methylamino-3-phenylpropanoic acid
MOD_RES N-methylphenylalanine
N-methyl-L-phenylalanine
N-methylated L-phenylalanine
N-methylphenylalanine
NMe1Phe
Methyl
Methylation
A protein modification that effectively converts an L-proline residue to N,N-dimethyl-L-proline.
29.06
C 2 H 5 N 0 O 0
29.038576
1+
C 7 H 13 N 1 O 1
127.19
127.09917
P
natural
N-term
Unimod:529
uniprot.ptm:PTM-0179
(2S)-2-carboxy-1,1-dimethylpyrrolidinium
1,1-dimethyl-L-prolinium
MOD_RES N,N-dimethylproline
N,N-dimethyl-L-proline
N,N-dimethyl-L-prolinium
N,N-dimethylated L-proline
NMe2Pro
stachydrin
PSI-MOD
Delta:H(5)C(2)
Dimethyl
Dimethylation of proline residue
MOD:00075
Unimod terminal specification corrected [JSG].
N,N-dimethyl-L-proline
A protein modification that effectively converts an L-proline residue to N,N-dimethyl-L-proline.
ChEBI:21451
PubMed:12964758
PubMed:14570711
PubMed:193025
PubMed:3882426
PubMed:6254758
RESID:AA0066
Unimod:529
(2S)-2-carboxy-1,1-dimethylpyrrolidinium
1,1-dimethyl-L-prolinium
MOD_RES N,N-dimethylproline
N,N-dimethyl-L-proline
N,N-dimethyl-L-prolinium
N,N-dimethylated L-proline
NMe2Pro
stachydrin
Delta:H(5)C(2)
Dimethyl
Dimethylation of proline residue
A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.
28.05
C 2 H 4 N 0 O 0
28.0313
C 8 H 16 N 4 O 1
184.24
184.13242
R
natural
Unimod:36
uniprot.ptm:PTM-0287
(2S)-2-amino-5-[((methylamino)(methylimino)methyl)amino]pentanoic acid
MOD_RES Omega-N-methylated arginine
MOD_RES Symmetric dimethylarginine
N3,N4-dimethylarginine
N5-[(methylamino)(methylimino)methyl]ornithine
NG,N'G-dimethylarginine
NoNo'Me2Arg
omega-N,omega-N'-dimethyl-L-arginine
omega-N,omega-N'-dimethylated L-arginine
symmetric dimethylarginine
PSI-MOD
Dimethyl
di-Methylation
MOD:00076
symmetric dimethyl-L-arginine
A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.
PubMed:12964758
PubMed:14570711
PubMed:15835918
PubMed:2426402
PubMed:5128665
RESID:AA0067
Unimod:36#R
(2S)-2-amino-5-[((methylamino)(methylimino)methyl)amino]pentanoic acid
MOD_RES Omega-N-methylated arginine
MOD_RES Symmetric dimethylarginine
N3,N4-dimethylarginine
N5-[(methylamino)(methylimino)methyl]ornithine
NG,N'G-dimethylarginine
NoNo'Me2Arg
omega-N,omega-N'-dimethyl-L-arginine
omega-N,omega-N'-dimethylated L-arginine
symmetric dimethylarginine
Dimethyl
di-Methylation
A protein modification that effectively converts an L-arginine residue to asymmetric dimethylarginine, N(omega),N(omega)-dimethyl-L-arginine.
28.05
C 2 H 4 N 0 O 0
28.0313
C 8 H 16 N 4 O 1
184.24
184.13242
R
natural
Unimod:36
uniprot.ptm:PTM-0066
(2S)-2-amino-5-([(dimethylamino)(imino)methyl]amino)pentanoic acid
MOD_RES Asymmetric dimethylarginine
MOD_RES Omega-N-methylated arginine
N5-[(dimethylamino)(imino)methyl]ornithine
NG,NG-dimethylarginine
NoNoMe2Arg
asymmetric dimethylarginine
omega-N,omega-N-dimethlyated L-arginine
omega-N,omega-N-dimethyl-L-arginine
PSI-MOD
Dimethyl
di-Methylation
MOD:00077
asymmetric dimethyl-L-arginine
A protein modification that effectively converts an L-arginine residue to asymmetric dimethylarginine, N(omega),N(omega)-dimethyl-L-arginine.
ChEBI:17929
PubMed:11152131
PubMed:12964758
PubMed:14570711
PubMed:15835918
PubMed:3032834
RESID:AA0068
Unimod:36#R
(2S)-2-amino-5-([(dimethylamino)(imino)methyl]amino)pentanoic acid
MOD_RES Asymmetric dimethylarginine
MOD_RES Omega-N-methylated arginine
N5-[(dimethylamino)(imino)methyl]ornithine
NG,NG-dimethylarginine
NoNoMe2Arg
asymmetric dimethylarginine
omega-N,omega-N-dimethlyated L-arginine
omega-N,omega-N-dimethyl-L-arginine
Dimethyl
di-Methylation
A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.
14.03
C 1 H 2 N 0 O 0
14.01565
C 7 H 14 N 4 O 1
170.22
170.11676
R
natural
uniprot.ptm:PTM-0237
(2S)-2-amino-5-[(imino(methylamino)methyl)amino]pentanoic acid
MOD_RES Omega-N-methylarginine
MOD_RES Omega-N-methylated arginine
NG-methylarginine
NoMeArg
omega-N-methyl-L-arginine
omega-N-methylated L-arginine
PSI-MOD
Methyl
Methylation
MOD:00078
omega-N-methyl-L-arginine
A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.
PubMed:11875433
PubMed:15835918
PubMed:2426402
PubMed:5128665
RESID:AA0069
(2S)-2-amino-5-[(imino(methylamino)methyl)amino]pentanoic acid
MOD_RES Omega-N-methylarginine
MOD_RES Omega-N-methylated arginine
NG-methylarginine
NoMeArg
omega-N-methyl-L-arginine
omega-N-methylated L-arginine
Methyl
Methylation
A protein modification that effectively converts an L-asparagine residue to N4-methyl-L-asparagine.
14.03
C 1 H 2 N 0 O 0
14.01565
C 5 H 8 N 2 O 2
128.13
128.05858
N
natural
Unimod:34
uniprot.ptm:PTM-0183
(2S)-2-amino-N4-methylbutanediamic acid
MOD_RES N4-methylasparagine
N(gamma)-methylasparagine
N-methylasparagine
N4-methyl-L-asparagine
N4-methylated L-asparagine
N4Me1Asn
beta-aspartyl methylamide
methyln
PSI-MOD
Methyl
Methylation
beta-methylasparagine
MOD:00079
N4-methyl-L-asparagine
A protein modification that effectively converts an L-asparagine residue to N4-methyl-L-asparagine.
OMSSA:75
PubMed:11875433
PubMed:2356973
PubMed:3782095
RESID:AA0070
Unimod:34#N
(2S)-2-amino-N4-methylbutanediamic acid
MOD_RES N4-methylasparagine
N(gamma)-methylasparagine
N-methylasparagine
N4-methyl-L-asparagine
N4-methylated L-asparagine
N4Me1Asn
beta-aspartyl methylamide
methyln
Methyl
Methylation
beta-methylasparagine
A protein modification that effectively converts an L-glutamine residue to N5-methyl-L-glutamine.
14.03
C 1 H 2 N 0 O 0
14.01565
C 6 H 10 N 2 O 2
142.16
142.07423
Q
natural
uniprot.ptm:PTM-0185
(2S)-2-amino-5-methylamino-5-oxopentanoic acid
2-amino-N5-methylpentanediamic acid
MOD_RES N5-methylglutamine
N(delta)-methylglutamine
N-methylglutamine
N5-methyl-L-glutamine
N5-methylated L-glutamine
N5Me1Gln
gamma-methylglutamine
PSI-MOD
Methyl
Methylation
MOD:00080
N5-methyl-L-glutamine
A protein modification that effectively converts an L-glutamine residue to N5-methyl-L-glutamine.
ChEBI:17592
DeltaMass:166
PubMed:11118225
PubMed:11875433
PubMed:365579
RESID:AA0071
(2S)-2-amino-5-methylamino-5-oxopentanoic acid
2-amino-N5-methylpentanediamic acid
MOD_RES N5-methylglutamine
N(delta)-methylglutamine
N-methylglutamine
N5-methyl-L-glutamine
N5-methylated L-glutamine
N5Me1Gln
gamma-methylglutamine
Methyl
Methylation
A protein modification that effectively converts an L-glutamic acid residue to L-glutamate 5-methyl ester.
14.03
C 1 H 2 N 0 O 0
14.01565
C 6 H 9 N 1 O 3
143.14
143.05824
E
natural
Unimod:34
uniprot.ptm:PTM-0128
(2S)-2-amino-5-methoxy-5-oxopentanoic acid
(5)-methyl L-hydrogen glutamate
2-aminopentanedioic acid 5-methyl ester
5-methyl L-2-aminoglutarate
5-methyl L-glutamate
5-methyl esterified L-glutamic acid
L-glutamic acid 5-methyl ester
MOD_RES Glutamate methyl ester (Glu)
O-methyl Glutamyl
O5MeGlu
glutamic acid 5-methyl ester
glutamic acid gamma-methyl ester
meestere
methyle
PSI-MOD
Methyl
Methylation
methyl ester
MOD:00081
DeltaMass gives the formula "C 6 H 9 O 1 N 3" with mass 143 (formula incorrect, N and O reversed) [JSG].
L-glutamic acid 5-methyl ester (Glu)
A protein modification that effectively converts an L-glutamic acid residue to L-glutamate 5-methyl ester.
DeltaMass:167
OMSSA:17
OMSSA:70
PubMed:16888
PubMed:6300110
RESID:AA0072#GLU
Unimod:34#E
(2S)-2-amino-5-methoxy-5-oxopentanoic acid
(5)-methyl L-hydrogen glutamate
2-aminopentanedioic acid 5-methyl ester
5-methyl L-2-aminoglutarate
5-methyl L-glutamate
5-methyl esterified L-glutamic acid
L-glutamic acid 5-methyl ester
MOD_RES Glutamate methyl ester (Glu)
O-methyl Glutamyl
O5MeGlu
glutamic acid 5-methyl ester
glutamic acid gamma-methyl ester
meestere
methyle
Methyl
Methylation
methyl ester
A protein modification that effectively converts an L-histidine residue to pros-methyl-L-histidine (N-pi-methyl-L-histidine, 3'-methyl-L-histidine).
14.03
C 1 H 2 N 0 O 0
14.01565
C 7 H 9 N 3 O 1
151.17
151.07455
H
natural
uniprot.ptm:PTM-0259
(2S)-2-amino-3-(3-methyl-3H-imidazol-4-yl)propanoic acid
3'-methyl-L-histidine
MOD_RES Pros-methylhistidine
N(delta)-methylhistidine
N(pi)-methylhistidine
NpMeHis
pros-methylated L-histidine
pros-methylhistidine
PSI-MOD
1-methylhistidine
Methyl
Methylation
MOD:00082
3'-methyl-L-histidine
A protein modification that effectively converts an L-histidine residue to pros-methyl-L-histidine (N-pi-methyl-L-histidine, 3'-methyl-L-histidine).
PubMed:10660523
PubMed:11875433
PubMed:3467365
PubMed:6692818
PubMed:8076
PubMed:8645219
RESID:AA0073
(2S)-2-amino-3-(3-methyl-3H-imidazol-4-yl)propanoic acid
3'-methyl-L-histidine
MOD_RES Pros-methylhistidine
N(delta)-methylhistidine
N(pi)-methylhistidine
NpMeHis
pros-methylated L-histidine
pros-methylhistidine
1-methylhistidine
Methyl
Methylation
A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.
43.09
C 3 H 7 N 0 O 0
43.054226
1+
C 9 H 19 N 2 O 1
171.26
171.14919
K
natural
uniprot.ptm:PTM-0187
(5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium
2-amino-6-(trimethylammonio)hexanoic acid
5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium
MOD_RES N6,N6,N6-trimethyllysine
N(zeta)-trimethyllysine
N-trimethylation (of lysine)
N6,N6,N6-trimethyl-L-lysine
N6,N6,N6-trimethylated L-lysine
N6,N6,N6-trimethyllysin-N6-ium
N6,N6,N6-trimethyllysine cation
N6Me3+Lys
epsilon-trimethyllysine
PSI-MOD
Trimethyl
tri-Methylation
MOD:00083
DeltaMass calculates the mass difference from protonated lysine rather than neutral lysine; for trimethylated lysine starting from protonated lysine see MOD:00855
N6,N6,N6-trimethyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.
ChEBI:17311
PubMed:12590383
PubMed:3145979
PubMed:4304194
PubMed:6778808
PubMed:7093227
PubMed:8453381
RESID:AA0074
(5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium
2-amino-6-(trimethylammonio)hexanoic acid
5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium
MOD_RES N6,N6,N6-trimethyllysine
N(zeta)-trimethyllysine
N-trimethylation (of lysine)
N6,N6,N6-trimethyl-L-lysine
N6,N6,N6-trimethylated L-lysine
N6,N6,N6-trimethyllysin-N6-ium
N6,N6,N6-trimethyllysine cation
N6Me3+Lys
epsilon-trimethyllysine
Trimethyl
tri-Methylation
A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.
28.05
C 2 H 4 N 0 O 0
28.0313
C 8 H 16 N 2 O 1
156.23
156.12627
K
natural
Unimod:36
uniprot.ptm:PTM-0188
(2S)-2-amino-6-(dimethylamino)hexanoic acid
MOD_RES N6,N6-dimethyllysine
N(zeta)-dimethyllysine
N6,N6-dimethyl-L-lysine
N6,N6-dimethylated L-lysine
N6Me2Lys
dimethylk
epsilon-dimethyllysine
lysine derivative Lys(y)
PSI-MOD
Dimethyl
di-Methylation
MOD:00084
N6,N6-dimethyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.
OMSSA:36
PubMed:10550045
PubMed:12964758
PubMed:14570711
PubMed:3100523
PubMed:8453381
RESID:AA0075
Unimod:36#K
(2S)-2-amino-6-(dimethylamino)hexanoic acid
MOD_RES N6,N6-dimethyllysine
N(zeta)-dimethyllysine
N6,N6-dimethyl-L-lysine
N6,N6-dimethylated L-lysine
N6Me2Lys
dimethylk
epsilon-dimethyllysine
lysine derivative Lys(y)
Dimethyl
di-Methylation
A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.
14.03
C 1 H 2 N 0 O 0
14.01565
C 7 H 14 N 2 O 1
142.2
142.11061
K
natural
Unimod:34
uniprot.ptm:PTM-0194
(2S)-2-amino-6-methylaminohexanoic acid
MOD_RES N6-methyllysine
N(zeta)-methyllysine
N-methyl Lysyl
N6-methyl-L-lysine
N6-methylated L-lysine
N6Me1Lys
epsilon-methyllysine
PSI-MOD
Methyl
Methylation
MOD:00085
N6-methyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.
ChEBI:17604
DeltaMass:165
PubMed:11875433
PubMed:3926756
RESID:AA0076
Unimod:34#K
(2S)-2-amino-6-methylaminohexanoic acid
MOD_RES N6-methyllysine
N(zeta)-methyllysine
N-methyl Lysyl
N6-methyl-L-lysine
N6-methylated L-lysine
N6Me1Lys
epsilon-methyllysine
Methyl
Methylation
A protein modification that effectively converts an L-lysine residue to N6-palmitoyl-L-lysine.
238.41
C 16 H 30 N 0 O 1
238.22966
C 22 H 42 N 2 O 2
366.59
366.32462
K
natural
Unimod:47
uniprot.ptm:PTM-0197
(2S)-2-amino-6-(hexadecanoylamino)hexanoic acid
2-amino-6-(hexadecanamido)hexanoic acid
LIPID N6-palmitoyl lysine
N(zeta)-palmitoyllysine
N6-(1-oxohexadecyl)-L-lysine
N6-hexadecanoylated L-lysine
N6-palmitoyl-L-lysine
N6-palmitoylated L-lysine
N6PamLys
epsilon-palmitoyllysine
palmitoylationk
PSI-MOD
Palmitoyl
Palmitoylation
MOD:00086
N6-palmitoyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N6-palmitoyl-L-lysine.
OMSSA:93
PubMed:2498336
PubMed:7801126
PubMed:7939682
RESID:AA0077
Unimod:47#K
(2S)-2-amino-6-(hexadecanoylamino)hexanoic acid
2-amino-6-(hexadecanamido)hexanoic acid
LIPID N6-palmitoyl lysine
N(zeta)-palmitoyllysine
N6-(1-oxohexadecyl)-L-lysine
N6-hexadecanoylated L-lysine
N6-palmitoyl-L-lysine
N6-palmitoylated L-lysine
N6PamLys
epsilon-palmitoyllysine
palmitoylationk
Palmitoyl
Palmitoylation
A protein modification that effectively converts an L-lysine residue to N6-myristoyl-L-lysine.
210.36
C 14 H 26 N 0 O 1
210.19836
C 20 H 38 N 2 O 2
338.54
338.29333
K
natural
Unimod:45
uniprot.ptm:PTM-0196
(2S)-2-amino-6-(tetradecanoylamino)hexanoic acid
2-amino-6-(tetradecanamido)hexanoic acid
LIPID N6-myristoyl lysine
N(zeta)-myristoyllysine
N6-(1-oxotetradecyl)-L-lysine
N6-(C14:0 aliphatic acyl)lysine
N6-myristoyl-L-lysine
N6-myristoylated L-lysine
N6MyrLys
epsilon-myristoyllysine
myristoylationk
PSI-MOD
Myristoyl
Myristoylation
MOD:00087
N6-myristoyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N6-myristoyl-L-lysine.
OMSSA:81
PubMed:1402651
PubMed:8346241
RESID:AA0078
Unimod:45#K
(2S)-2-amino-6-(tetradecanoylamino)hexanoic acid
2-amino-6-(tetradecanamido)hexanoic acid
LIPID N6-myristoyl lysine
N(zeta)-myristoyllysine
N6-(1-oxotetradecyl)-L-lysine
N6-(C14:0 aliphatic acyl)lysine
N6-myristoyl-L-lysine
N6-myristoylated L-lysine
N6MyrLys
epsilon-myristoyllysine
myristoylationk
Myristoyl
Myristoylation
A protein modification that effectively converts an L-threonine residue to O-palmitoyl-L-threonine.
238.41
C 16 H 30 N 0 O 1
238.22966
C 20 H 37 N 1 O 3
339.52
339.27734
T
natural
Unimod:47
uniprot.ptm:PTM-0242
(2S,3R)-2-amino-3-(hexadecanoyloxy)butanoic acid
L-threonine hexadecanoate ester
LIPID O-palmitoyl threonine
O-hexadecanoylated L-threonine
O-palmitoyl-L-threonine
O-palmitoylated L-threonine
O3-palmitoyl-threonine
OPamThr
palmitoylationt
threonine palmitate ester
PSI-MOD
Palmitoyl
Palmitoylation
MOD:00088
O-palmitoyl-L-threonine
A protein modification that effectively converts an L-threonine residue to O-palmitoyl-L-threonine.
OMSSA:95
PubMed:6642431
PubMed:8413602
RESID:AA0079
Unimod:47#T
(2S,3R)-2-amino-3-(hexadecanoyloxy)butanoic acid
L-threonine hexadecanoate ester
LIPID O-palmitoyl threonine
O-hexadecanoylated L-threonine
O-palmitoyl-L-threonine
O-palmitoylated L-threonine
O3-palmitoyl-threonine
OPamThr
palmitoylationt
threonine palmitate ester
Palmitoyl
Palmitoylation
A protein modification that effectively converts an L-serine residue to O-palmitoyl-L-serine.
238.41
C 16 H 30 N 0 O 1
238.22966
C 19 H 35 N 1 O 3
325.49
325.2617
S
natural
Unimod:47
uniprot.ptm:PTM-0241
(2S)-2-amino-3-(hexadecanoyloxy)propanoic acid
ACT_SITE O-palmitoyl serine intermediate
L-serine hexadecanoate ester
LIPID O-palmitoyl serine
O-hexadecanoylated L-serine
O-palmitoyl-L-serine
O-palmitoylated L-serine
O3-palmitoyl-serine
OPamSer
palmitoylations
serine palmitate ester
PSI-MOD
Palmitoyl
Palmitoylation
MOD:00089
O-palmitoyl-L-serine
A protein modification that effectively converts an L-serine residue to O-palmitoyl-L-serine.
OMSSA:94
PubMed:3467339
RESID:AA0080
Unimod:47#S
(2S)-2-amino-3-(hexadecanoyloxy)propanoic acid
ACT_SITE O-palmitoyl serine intermediate
L-serine hexadecanoate ester
LIPID O-palmitoyl serine
O-hexadecanoylated L-serine
O-palmitoyl-L-serine
O-palmitoylated L-serine
O3-palmitoyl-serine
OPamSer
palmitoylations
serine palmitate ester
Palmitoyl
Palmitoylation
A protein modification that effectively converts an L-alanine residue to L-alanine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 3 H 7 N 2 O 1
87.1
87.05584
A
natural
C-term
uniprot.ptm:PTM-0057
(2S)-2-aminopropanamide
AlaN
L-alanine amide
MOD_RES Alanine amide
alaninamide
amidated L-alanine
PSI-MOD
MOD:00090
L-alanine amide
A protein modification that effectively converts an L-alanine residue to L-alanine amide.
PubMed:1377792
PubMed:2069951
PubMed:8472537
PubMed:952951
RESID:AA0081
(2S)-2-aminopropanamide
AlaN
L-alanine amide
MOD_RES Alanine amide
alaninamide
amidated L-alanine
A protein modification that effectively converts an L-arginine residue to L-arginine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 6 H 14 N 5 O 1
172.21
172.11984
R
natural
C-term
uniprot.ptm:PTM-0060
(2S)-2-amino-5-[(diaminomethylidene)amino]pentanamide
2-amino-5-carbamimidamidopentanamide
2-amino-5-guanidinopentanamide
ArgN
L-arginine amide
MOD_RES Arginine amide
amidated L-arginine
argininamide
PSI-MOD
MOD:00091
L-arginine amide
A protein modification that effectively converts an L-arginine residue to L-arginine amide.
ChEBI:145897
PubMed:2229025
PubMed:2753890
PubMed:743209
RESID:AA0082
(2S)-2-amino-5-[(diaminomethylidene)amino]pentanamide
2-amino-5-carbamimidamidopentanamide
2-amino-5-guanidinopentanamide
ArgN
L-arginine amide
MOD_RES Arginine amide
amidated L-arginine
argininamide
A protein modification that effectively converts an L-asparagine residue to L-asparagine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 4 H 8 N 3 O 2
130.13
130.06165
N
natural
C-term
uniprot.ptm:PTM-0062
(2S)-2-aminobutanediamide
AsnN
L-asparagine amide
MOD_RES Asparagine amide
amidated L-asparagine
asparaginamide
PSI-MOD
MOD:00092
L-asparagine amide
A protein modification that effectively converts an L-asparagine residue to L-asparagine amide.
ChEBI:145898
PubMed:2753132
PubMed:279902
PubMed:3415690
RESID:AA0083
(2S)-2-aminobutanediamide
AsnN
L-asparagine amide
MOD_RES Asparagine amide
amidated L-asparagine
asparaginamide
A protein modification that effectively converts an L-aspartic acid residue to L-aspartic acid 1-amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 4 H 7 N 2 O 3
131.11
131.04567
D
natural
C-term
uniprot.ptm:PTM-0063
(2S)-2-amino-1-butanediamic acid
1-amidated L-aspartic acid
3,4-diamino-4-oxobutanoic acid
3-amino-succinamic acid
AspN
L-aspartic acid 1-amide
MOD_RES Aspartic acid 1-amide
alpha-asparagine
isoasparagine
PSI-MOD
MOD:00093
L-aspartic acid 1-amide
A protein modification that effectively converts an L-aspartic acid residue to L-aspartic acid 1-amide.
PubMed:2542051
RESID:AA0084
(2S)-2-amino-1-butanediamic acid
1-amidated L-aspartic acid
3,4-diamino-4-oxobutanoic acid
3-amino-succinamic acid
AspN
L-aspartic acid 1-amide
MOD_RES Aspartic acid 1-amide
alpha-asparagine
isoasparagine
A protein modification that effectively converts an L-cysteine residue to L-cysteine amide.
-0.98
C 0 H 1 N 1 O -1 S 0
-0.984016
C 3 H 7 N 2 O 1 S 1
119.16
119.02791
C
natural
C-term
uniprot.ptm:PTM-0102
(2R)-2-amino-3-sulfanylpropanamide
2-amino-3-mercaptopropanamide
CysN
L-cysteine amide
MOD_RES Cysteine amide
amidated L-cysteine
cysteinamide
PSI-MOD
MOD:00094
L-cysteine amide
A protein modification that effectively converts an L-cysteine residue to L-cysteine amide.
PubMed:1892838
PubMed:7149738
RESID:AA0085
(2R)-2-amino-3-sulfanylpropanamide
2-amino-3-mercaptopropanamide
CysN
L-cysteine amide
MOD_RES Cysteine amide
amidated L-cysteine
cysteinamide
A protein modification that effectively converts an L-glutamine residue to L-glutamine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 5 H 10 N 3 O 2
144.15
144.0773
Q
natural
C-term
uniprot.ptm:PTM-0130
(2S)-2-aminopentanediamide
GlnN
L-glutamine amide
MOD_RES Glutamine amide
amidated L-glutamine
glutaminamide
PSI-MOD
MOD:00095
L-glutamine amide
A protein modification that effectively converts an L-glutamine residue to L-glutamine amide.
PubMed:7673220
PubMed:9048550
RESID:AA0086
(2S)-2-aminopentanediamide
GlnN
L-glutamine amide
MOD_RES Glutamine amide
amidated L-glutamine
glutaminamide
A protein modification that effectively converts an L-glutamic acid residue to L-glutamic acid 1-amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 5 H 9 N 2 O 3
145.14
145.06131
E
natural
C-term
uniprot.ptm:PTM-0129
(2S)-2-amino-1-pentanediamic acid
1-amidated L-glutamic acid
4,5-diamino-5-oxopentanoic acid
GluN
L-glutamic acid 1-amide
MOD_RES Glutamic acid 1-amide
isoglutamine
PSI-MOD
MOD:00096
L-glutamic acid 1-amide
A protein modification that effectively converts an L-glutamic acid residue to L-glutamic acid 1-amide.
PubMed:1093875
PubMed:14550575
RESID:AA0087
(2S)-2-amino-1-pentanediamic acid
1-amidated L-glutamic acid
4,5-diamino-5-oxopentanoic acid
GluN
L-glutamic acid 1-amide
MOD_RES Glutamic acid 1-amide
isoglutamine
A protein modification that effectively converts a glycine residue to glycine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 2 H 5 N 2 O 1
73.07
73.04019
G
natural
C-term
uniprot.ptm:PTM-0132
2-aminoacetamide
2-aminoethanamide
2-azanylethanamide
GlyN
MOD_RES Glycine amide
amidated glycine
glycinamide
glycine amide
PSI-MOD
MOD:00097
glycine amide
A protein modification that effectively converts a glycine residue to glycine amide.
PubMed:13591312
RESID:AA0088
2-aminoacetamide
2-aminoethanamide
2-azanylethanamide
GlyN
MOD_RES Glycine amide
amidated glycine
glycinamide
glycine amide
A protein modification that effectively converts an L-histidine residue to L-histidine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 6 H 9 N 4 O 1
153.16
153.07764
H
natural
C-term
uniprot.ptm:PTM-0148
(2S)-2-amino-3-(1H-imidazol-4-yl)propanamide
HisN
L-histidine amide
MOD_RES Histidine amide
amidated L-histidine
histidinamide
PSI-MOD
MOD:00098
L-histidine amide
A protein modification that effectively converts an L-histidine residue to L-histidine amide.
PubMed:2153586
PubMed:2307683
PubMed:2839478
RESID:AA0089
(2S)-2-amino-3-(1H-imidazol-4-yl)propanamide
HisN
L-histidine amide
MOD_RES Histidine amide
amidated L-histidine
histidinamide
A protein modification that effectively converts an L-isoleucine residue to L-isoleucine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 6 H 13 N 2 O 1
129.18
129.10278
I
natural
C-term
uniprot.ptm:PTM-0161
(2S,3S)-2-amino-3-methylpentanamide
IleN
L-isoleucine amide
MOD_RES Isoleucine amide
amidated L-isoleucine
isoleucinamide
PSI-MOD
MOD:00099
L-isoleucine amide
A protein modification that effectively converts an L-isoleucine residue to L-isoleucine amide.
RESID:AA0090
(2S,3S)-2-amino-3-methylpentanamide
IleN
L-isoleucine amide
MOD_RES Isoleucine amide
amidated L-isoleucine
isoleucinamide
A protein modification that effectively converts an L-leucine residue to L-leucine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 6 H 13 N 2 O 1
129.18
129.10278
L
natural
C-term
uniprot.ptm:PTM-0166
(2S)-2-amino-4-methylpentanamide
2-amino-4-methylvaleramide
2-azanyl-4-methylpentanamide
L-leucine amide
LeuN
MOD_RES Leucine amide
alpha-aminoisocaproamide
amidated L-leucine
leucinamide
PSI-MOD
MOD:00100
L-leucine amide
A protein modification that effectively converts an L-leucine residue to L-leucine amide.
PubMed:2578459
RESID:AA0091
(2S)-2-amino-4-methylpentanamide
2-amino-4-methylvaleramide
2-azanyl-4-methylpentanamide
L-leucine amide
LeuN
MOD_RES Leucine amide
alpha-aminoisocaproamide
amidated L-leucine
leucinamide
A protein modification that effectively converts an L-lysine residue to L-lysine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 6 H 14 N 3 O 1
144.2
144.1137
K
natural
C-term
uniprot.ptm:PTM-0168
(2S)-2,6-diaminohexanamide
L-lysine amide
LysN
MOD_RES Lysine amide
amidated L-lysine
lysinamide
PSI-MOD
MOD:00101
L-lysine amide
A protein modification that effectively converts an L-lysine residue to L-lysine amide.
PubMed:6579533
RESID:AA0092
(2S)-2,6-diaminohexanamide
L-lysine amide
LysN
MOD_RES Lysine amide
amidated L-lysine
lysinamide
A protein modification that effectively converts an L-methionine residue to L-methionine amide.
-0.98
C 0 H 1 N 1 O -1 S 0
-0.984016
C 5 H 11 N 2 O 1 S 1
147.22
147.0592
M
natural
C-term
uniprot.ptm:PTM-0164
(2S)-2-amino-4-(methylsulfanyl)butanamide
2-amino-4-(methylthio)butanamide
L-methionine amide
MOD_RES Methionine amide
MetN
amidated L-methionine
methioninamide
PSI-MOD
MOD:00102
L-methionine amide
methioninamide
A protein modification that effectively converts an L-methionine residue to L-methionine amide.
PubMed:4375977
RESID:AA0093
(2S)-2-amino-4-(methylsulfanyl)butanamide
2-amino-4-(methylthio)butanamide
L-methionine amide
MOD_RES Methionine amide
MetN
amidated L-methionine
A protein modification that effectively converts an L-phenylalanine residue to L-phenylalanine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 9 H 11 N 2 O 1
163.2
163.08714
F
natural
C-term
uniprot.ptm:PTM-0248
(2S)-2-amino-3-phenylpropanamide
L-phenylalanine amide
MOD_RES Phenylalanine amide
PheN
amidated L-phenylalanine
phenylalaninamide
PSI-MOD
MOD:00103
L-phenylalanine amide
A protein modification that effectively converts an L-phenylalanine residue to L-phenylalanine amide.
PubMed:2905621
PubMed:8868490
RESID:AA0094
(2S)-2-amino-3-phenylpropanamide
L-phenylalanine amide
MOD_RES Phenylalanine amide
PheN
amidated L-phenylalanine
phenylalaninamide
A protein modification that effectively converts an L-proline residue to L-proline amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 5 H 9 N 2 O 1
113.14
113.07149
P
natural
C-term
uniprot.ptm:PTM-0257
(2S)-pyrrolidine-2-carboxamide
L-proline amide
MOD_RES Proline amide
ProN
amidated L-proline
prolinamide
PSI-MOD
MOD:00104
L-proline amide
A protein modification that effectively converts an L-proline residue to L-proline amide.
PubMed:4982117
PubMed:5760861
RESID:AA0095
(2S)-pyrrolidine-2-carboxamide
L-proline amide
MOD_RES Proline amide
ProN
amidated L-proline
prolinamide
A protein modification that effectively converts an L-serine residue to L-serine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 3 H 7 N 2 O 2
103.1
103.05075
S
natural
C-term
uniprot.ptm:PTM-0275
(2S)-2-amino-3-hydroxypropanamide
L-serine amide
MOD_RES Serine amide
SerN
amidated L-serine
serinamide
PSI-MOD
MOD:00105
L-serine amide
A protein modification that effectively converts an L-serine residue to L-serine amide.
PubMed:743209
RESID:AA0096
(2S)-2-amino-3-hydroxypropanamide
L-serine amide
MOD_RES Serine amide
SerN
amidated L-serine
serinamide
A protein modification that effectively converts an L-threonine residue to L-threonine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 4 H 9 N 2 O 2
117.13
117.06641
T
natural
C-term
uniprot.ptm:PTM-0293
(2S,3R)-2-amino-3-hydroxybutanamide
L-threonine amide
MOD_RES Threonine amide
ThrN
amidated L-threonine
threoninamide
PSI-MOD
MOD:00106
L-threonine amide
A protein modification that effectively converts an L-threonine residue to L-threonine amide.
PubMed:1390774
RESID:AA0097
(2S,3R)-2-amino-3-hydroxybutanamide
L-threonine amide
MOD_RES Threonine amide
ThrN
amidated L-threonine
threoninamide
A protein modification that effectively converts an L-tryptophan residue to L-tryptophan amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 11 H 12 N 3 O 1
202.24
202.09804
W
natural
C-term
uniprot.ptm:PTM-0296
(2S)-2-amino-3-(1H-indol-3-yl)propanamide
L-tryptophan amide
MOD_RES Tryptophan amide
TrpN
amidated L-tryptophan
tryptophanamide
PSI-MOD
MOD:00107
L-tryptophan amide
A protein modification that effectively converts an L-tryptophan residue to L-tryptophan amide.
PubMed:3947348
RESID:AA0098
(2S)-2-amino-3-(1H-indol-3-yl)propanamide
L-tryptophan amide
MOD_RES Tryptophan amide
TrpN
amidated L-tryptophan
tryptophanamide
A protein modification that effectively converts an L-tyrosine residue to L-tyrosine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 9 H 11 N 2 O 2
179.2
179.08205
Y
natural
C-term
uniprot.ptm:PTM-0302
(2S)-2-amino-3-(4-hydoxyphenyl)propanamide
L-tyrosine amide
MOD_RES Tyrosine amide
TyrN
amidated L-tyrosine
tyrosinamide
PSI-MOD
MOD:00108
L-tyrosine amide
A protein modification that effectively converts an L-tyrosine residue to L-tyrosine amide.
PubMed:1377792
PubMed:3562898
PubMed:6509012
RESID:AA0099
(2S)-2-amino-3-(4-hydoxyphenyl)propanamide
L-tyrosine amide
MOD_RES Tyrosine amide
TyrN
amidated L-tyrosine
tyrosinamide
A protein modification that effectively converts an L-valine residue to L-valine amide.
-0.98
C 0 H 1 N 1 O -1
-0.984016
C 5 H 11 N 2 O 1
115.16
115.087135
V
natural
C-term
uniprot.ptm:PTM-0303
(2S)-2-amino-3-methylbutanamide
L-valine amide
MOD_RES Valine amide
ValN
valinamide
PSI-MOD
MOD:00109
L-valine amide
A protein modification that effectively converts an L-valine residue to L-valine amide.
PubMed:2578459
PubMed:5465996
RESID:AA0100
(2S)-2-amino-3-methylbutanamide
L-valine amide
MOD_RES Valine amide
ValN
valinamide
A protein modification that effectively converts an L-cysteine residue to L-cysteine methyl disulfide.
46.09
C 1 H 2 N 0 O 0 S 1
45.98772
C 4 H 7 N 1 O 1 S 2
149.23
148.9969
C
natural
Unimod:39
uniprot.ptm:PTM-0104
(2R)-2-amino-3-(methyldisulfanediyl)propanoic acid
2-amino-3-(methyldisulfanediyl)propanoic acid
2-amino-3-(methyldithio)propanoic acid
2-amino-3-methyldisulfanylpropanoic acid
2-azanyl-3-(methyldisulfanediyl)-propanoic acid
L-3-(methyldithio)alanine
L-cysteine methyl disulfide
MOD_RES Cysteine methyl disulfide
S-methylthio-L-cysteine
S-methylthiocysteine
methyl methanethiolsulfonate derivatized cysteine
methyl methanethiosulfonate derivatized cysteine
mmts
PSI-MOD
Beta-methylthiolation
Methylthio
MOD:00110
Produced artifactually by reaction of cysteine residues with methyl methanethiosulfonate (MMTS) [JSG], but also naturally in bacteria [PMT].
L-cysteine methyl disulfide
A protein modification that effectively converts an L-cysteine residue to L-cysteine methyl disulfide.
OMSSA:179
PubMed:10555576
PubMed:163643
PubMed:2056535
PubMed:6381494
RESID:AA0101
Unimod:39#C
(2R)-2-amino-3-(methyldisulfanediyl)propanoic acid
2-amino-3-(methyldisulfanediyl)propanoic acid
2-amino-3-(methyldithio)propanoic acid
2-amino-3-methyldisulfanylpropanoic acid
2-azanyl-3-(methyldisulfanediyl)-propanoic acid
L-3-(methyldithio)alanine
L-cysteine methyl disulfide
MOD_RES Cysteine methyl disulfide
S-methylthio-L-cysteine
S-methylthiocysteine
methyl methanethiolsulfonate derivatized cysteine
methyl methanethiosulfonate derivatized cysteine
mmts
Beta-methylthiolation
Methylthio
Methylthio
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine.
204.36
C 15 H 24 N 0 O 0 S 0
204.1878
C 18 H 29 N 1 O 1 S 1
307.5
307.197
C
natural
Unimod:44
uniprot.ptm:PTM-0277
(2R)-2-amino-3-([(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid
2-amino-3-(3,7,11-trimethyl-2,6,10-dodecatrienylthio)propanoic acid
LIPID S-farnesyl cysteine
S-farnesyl Cystenyl
S-farnesyl-L-cysteine
SFarnCys
farnesylationc
PSI-MOD
Farnesyl
Farnesylation
MOD:00111
From DeltaMass: (name misspelled "S-farnesyl cystenyl")
S-farnesyl-L-cysteine
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine.
DeltaMass:293
OMSSA:42
PubMed:1409665
PubMed:15609361
PubMed:1872463
PubMed:2684976
RESID:AA0102
Unimod:44#C
(2R)-2-amino-3-([(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid
2-amino-3-(3,7,11-trimethyl-2,6,10-dodecatrienylthio)propanoic acid
LIPID S-farnesyl cysteine
S-farnesyl Cystenyl
S-farnesyl-L-cysteine
SFarnCys
farnesylationc
Farnesyl
Farnesylation
A protein modification that effectively converts an L-cysteine residue to S-12-hydroxyfarnesyl-L-cysteine.
220.36
C 15 H 24 N 0 O 1 S 0
220.18271
C 18 H 29 N 1 O 2 S 1
323.5
323.1919
C
natural
Unimod:376
uniprot.ptm:PTM-0269
(2R)-2-amino-3-([(2E,6E,10Z)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid
2-amino-3-(12-hydroxy-3,7,11-trimethyl-3,6,10-dodecatrienylthio)propanoic acid
LIPID S-12-hydroxyfarnesyl cysteine
S-12-hydroxyfarnesyl-L-cysteine
S12HyFarnCys
PSI-MOD
Hydroxyfarnesyl
hydroxyfarnesyl
MOD:00112
S-12-hydroxyfarnesyl-L-cysteine
A protein modification that effectively converts an L-cysteine residue to S-12-hydroxyfarnesyl-L-cysteine.
PubMed:17790543
RESID:AA0103
Unimod:376
(2R)-2-amino-3-([(2E,6E,10Z)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid
2-amino-3-(12-hydroxy-3,7,11-trimethyl-3,6,10-dodecatrienylthio)propanoic acid
LIPID S-12-hydroxyfarnesyl cysteine
S-12-hydroxyfarnesyl-L-cysteine
S12HyFarnCys
Hydroxyfarnesyl
hydroxyfarnesyl
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
272.48
C 20 H 32 N 0 O 0 S 0
272.2504
C 23 H 37 N 1 O 1 S 1
375.62
375.25958
C
natural
Unimod:48
uniprot.ptm:PTM-0278
(2R)-2-amino-3-([(2E,6E,10Z)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid
2-amino-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenylthio)propanoic acid
LIPID S-geranylgeranyl cysteine
S-geranylgeranyl
S-geranylgeranyl-L-cysteine
SGergerCys
geranylgeranylc
PSI-MOD
Geranyl-geranyl
GeranylGeranyl
MOD:00113
DeltaMass calculates the mass with two double bonds rather than four
S-geranylgeranyl-L-cysteine
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
DeltaMass:0
OMSSA:49
PubMed:1483450
PubMed:15609361
RESID:AA0104
Unimod:48#C
(2R)-2-amino-3-([(2E,6E,10Z)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acid
2-amino-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenylthio)propanoic acid
LIPID S-geranylgeranyl cysteine
S-geranylgeranyl
S-geranylgeranyl-L-cysteine
SGergerCys
geranylgeranylc
Geranyl-geranyl
GeranylGeranyl
A protein modification that effectively converts an L-cysteine residue to L-cysteine methyl ester.
14.03
C 1 H 2 N 0 O 0 S 0
14.01565
C 4 H 8 N 1 O 2 S 1
134.17
134.02757
C
natural
C-term
Unimod:34
uniprot.ptm:PTM-0105
2-amino-3-mercaptopropanoic methyl ester
2-amino-3-sulfanylpropanoic methyl ester
L-cysteine methyl ester
MOD_RES Cysteine methyl ester
OMeCys
mecysteine
methyl (2R)-2-amino-3-sulfanylpropanoate
methyl L-cysteinate
methyl esterified L-cysteine
PSI-MOD
Methyl
Methylation
MOD:00114
Secondary to RESID:AA0102; secondary to RESID:AA0103; secondary to RESID:AA0104.
L-cysteine methyl ester
A protein modification that effectively converts an L-cysteine residue to L-cysteine methyl ester.
PubMed:11875433
PubMed:1872463
RESID:AA0105
Unimod:34#C-term
2-amino-3-mercaptopropanoic methyl ester
2-amino-3-sulfanylpropanoic methyl ester
L-cysteine methyl ester
MOD_RES Cysteine methyl ester
OMeCys
mecysteine
methyl (2R)-2-amino-3-sulfanylpropanoate
methyl L-cysteinate
methyl esterified L-cysteine
Methyl
Methylation
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
238.41
C 16 H 30 N 0 O 1 S 0
238.22966
C 19 H 35 N 1 O 2 S 1
341.55
341.23886
C
natural
Unimod:47
uniprot.ptm:PTM-0281
(2R)-2-amino-3-(hexadecanoylsulfanyl)propanoic acid
2-amino-3-(hexadecanoylthio)propanoic acid
ACT_SITE S-palmitoyl cysteine intermediate
LIPID S-palmitoyl cysteine
S-hexadecanoylated L-cysteine
S-palmitoyl-L-cysteine
S-palmitoylated L-cysteine
S-palmityl Cystenyl
SPamCys
cysteine hexadecanoate thioester
cysteine palmitate thioester
PSI-MOD
Palmitoyl
Palmitoylation
MOD:00115
From DeltaMass: (name misspelled "S-palmityl Cystenyl" and formula incorrect, N and O reversed) Formula: C19H35O1N2S1 Monoisotopic Mass Change: 341.239 Average Mass Change: 341.556
S-palmitoyl-L-cysteine
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
DeltaMass:303
PubMed:1872406
PubMed:3166978
PubMed:8180229
PubMed:8824274
RESID:AA0106
Unimod:47#C
(2R)-2-amino-3-(hexadecanoylsulfanyl)propanoic acid
2-amino-3-(hexadecanoylthio)propanoic acid
ACT_SITE S-palmitoyl cysteine intermediate
LIPID S-palmitoyl cysteine
S-hexadecanoylated L-cysteine
S-palmitoyl-L-cysteine
S-palmitoylated L-cysteine
S-palmityl Cystenyl
SPamCys
cysteine hexadecanoate thioester
cysteine palmitate thioester
Palmitoyl
Palmitoylation
A protein modification that effectively converts an L-cysteine residue to S-diacylglycerol-L-cysteine.
C
natural
uniprot.ptm:PTM-0274
(2R)-2-amino-3-[(2S)-2-((9Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]sulfanylpropanoic acid
2-amino-3-[(S)-2-((Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]thiopropanoic acid
LIPID S-diacylglycerol cysteine
S-(1-2'-oleoyl-3'-palmitoyl-glycerol)cysteine
S-(2',3'-diacylglycerol)-L-cysteine
S-diacylglycerol-L-cysteine
SAcyl2GlyceroCys
PSI-MOD
Diacylglycerol
diacylglycerol
MOD:00116
Incidental to RESID:AA0060.
S-diacylglycerol-L-cysteine
A protein modification that effectively converts an L-cysteine residue to S-diacylglycerol-L-cysteine.
PubMed:10896212
PubMed:4575979
PubMed:9056182
RESID:AA0107
Unimod:377#C
(2R)-2-amino-3-[(2S)-2-((9Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]sulfanylpropanoic acid
2-amino-3-[(S)-2-((Z)-9-octadecenoyloxy)-3-(hexadecanoyloxy)propyl]thiopropanoic acid
LIPID S-diacylglycerol cysteine
S-(1-2'-oleoyl-3'-palmitoyl-glycerol)cysteine
S-(2',3'-diacylglycerol)-L-cysteine
S-diacylglycerol-L-cysteine
SAcyl2GlyceroCys
Diacylglycerol
diacylglycerol
A protein modification that effectively crosslinks an L-cysteine residue and an L-glutamine residue by a thioester bond with the formation of S-(L-isoglutamyl)-L-cysteine and the release of ammonia.
-17.03
C 0 H -3 N -1 O 0 S 0
-17.026548
C 8 H 10 N 2 O 3 S 1
214.24
214.04121
C, Q
natural
uniprot.ptm:PTM-0156
(2S)-2-amino-5-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5-oxopentanoic acid
(S,R)-2-amino-4-[S-(2-amino-2-carboxyethyl)thiocarboxy]butanoic acid
2-amino-5-(2-amino-2-carboxyethyl)thio-5-oxopentanoic acid
CROSSLNK Isoglutamyl cysteine thioester (Cys-Gln)
S-(L-isoglutamyl)-L-cysteine
S-gamma-glutamyl (crosslinked to cysteine)
XLNK-SCys-5Glu(Gln)
gamma-(S-cysteinyl)glutamic acid
PSI-MOD
MOD:00117
Cross-link 2; DeltaMass calculates the mass difference from glutamic acid rather than glutamine.
S-(L-isoglutamyl)-L-cysteine
A protein modification that effectively crosslinks an L-cysteine residue and an L-glutamine residue by a thioester bond with the formation of S-(L-isoglutamyl)-L-cysteine and the release of ammonia.
ChEBI:22021
DeltaMass:0
PubMed:6838833
RESID:AA0108
(2S)-2-amino-5-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5-oxopentanoic acid
(S,R)-2-amino-4-[S-(2-amino-2-carboxyethyl)thiocarboxy]butanoic acid
2-amino-5-(2-amino-2-carboxyethyl)thio-5-oxopentanoic acid
CROSSLNK Isoglutamyl cysteine thioester (Cys-Gln)
S-(L-isoglutamyl)-L-cysteine
S-gamma-glutamyl (crosslinked to cysteine)
XLNK-SCys-5Glu(Gln)
gamma-(S-cysteinyl)glutamic acid
A protein modification that effectively cross-links an L-cysteine residue and an L-histidine residue by a thioether bond to form 2'-(S-L-cysteinyl)-L-histidine.
-2.02
C 0 H -2 N 0 O 0 S 0
-2.01565
C 9 H 10 N 4 O 2 S 1
238.26
238.05244
C, H
natural
uniprot.ptm:PTM-0005
(2R)-2-amino-3-[(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)sulfanyl]propanoic acid
(2S)-2-amino-3-[2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-1H-imidazol-4-yl]propanoic acid
2'-(L-cystein-S-yl)-L-histidine
CROSSLNK 2'-(S-cysteinyl)-histidine (Cys-His)
S-(2'-histidyl)cysteine
S-(2-histidyl)- (crosslinked to cysteine)
XLNK-SCys-2'His
PSI-MOD
MOD:00118
Cross-link 2.
2'-(S-L-cysteinyl)-L-histidine
A protein modification that effectively cross-links an L-cysteine residue and an L-histidine residue by a thioether bond to form 2'-(S-L-cysteinyl)-L-histidine.
DeltaMass:0
PubMed:6210696
RESID:AA0109
(2R)-2-amino-3-[(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)sulfanyl]propanoic acid
(2S)-2-amino-3-[2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-1H-imidazol-4-yl]propanoic acid
2'-(L-cystein-S-yl)-L-histidine
CROSSLNK 2'-(S-cysteinyl)-histidine (Cys-His)
S-(2'-histidyl)cysteine
S-(2-histidyl)- (crosslinked to cysteine)
XLNK-SCys-2'His
A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form L-lanthionine.
-18.02
C 0 H -2 N 0 O -1 S 0
-18.010565
C 6 H 8 N 2 O 2 S 1
172.2
172.03065
C, S
artifact
(2R,2'R)-3,3'-sulfanediylbis(2-aminopropanoic acid)
(R)-S-(2-amino-2-carboxyethyl)-L-cysteine
(R,R)-2,6-diamino-4-thiaheptanedioic acid
(R,R)-3,3'-thiobis-(2-aminopropanoic acid)
(R,R)-bis(2-amino-2-carboxyethyl)sulfide
2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid
3,3'-thiobis-L-alanine
L-lanthionine
XLNK-SCys-(L)3Dha
PSI-MOD
MOD:00119
Cross-link 2. The natural occurrence of this modification is rare. For the more common modification see MOD:00120 meso-lanthionine [JSG].
L-lanthionine (Cys-Ser)
A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form L-lanthionine.
ChEBI:21347
DeltaMass:7
RESID:AA0110#CSX
(2R,2'R)-3,3'-sulfanediylbis(2-aminopropanoic acid)
(R)-S-(2-amino-2-carboxyethyl)-L-cysteine
(R,R)-2,6-diamino-4-thiaheptanedioic acid
(R,R)-3,3'-thiobis-(2-aminopropanoic acid)
(R,R)-bis(2-amino-2-carboxyethyl)sulfide
2-amino-3-(2-amino-2-carboxyethyl)sulfanylpropanoic acid
3,3'-thiobis-L-alanine
L-lanthionine
XLNK-SCys-(L)3Dha
A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form meso-lanthionine.
-18.02
C 0 H -2 N 0 O -1 S 0
-18.010565
C 6 H 8 N 2 O 2 S 1
172.2
172.03065
C, S
natural
uniprot.ptm:PTM-0164
(2R,2'S)-3,3'-sulfanediylbis(2-aminopropanoic acid)
(2R,2'S)-3,3'-thiobis-(2-aminopropanoic acid)
(2R,6S)-2,6-diamino-4-thiaheptanedioic acid
(2R,6S)-meso-lanthionine
(2S)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]sulfanyl]propanoic acid
(R)-S-(2-amino-2-carboxyethyl)-D-cysteine
(R,S)-bis(2-amino-2-carboxyethyl)sulfide
3,3'-thiobis-meso-alanine
CROSSLNK Lanthionine (Cys-Ser)
CROSSLNK Lanthionine (Ser-Cys)
XLNK-SCys-(D)3Dha
cysteine-3-D-alanine thioether
meso-lanthionine
PSI-MOD
(2S,6R)-meso-lanthionine
MOD:00120
Cross-link 2.
meso-lanthionine
A protein modification that effectively cross-links an L-cysteine residue and an L-serine residue by a thioether bond to form meso-lanthionine.
PubMed:15023056
PubMed:3769923
RESID:AA0111
(2R,2'S)-3,3'-sulfanediylbis(2-aminopropanoic acid)
(2R,2'S)-3,3'-thiobis-(2-aminopropanoic acid)
(2R,6S)-2,6-diamino-4-thiaheptanedioic acid
(2R,6S)-meso-lanthionine
(2S)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]sulfanyl]propanoic acid
(R)-S-(2-amino-2-carboxyethyl)-D-cysteine
(R,S)-bis(2-amino-2-carboxyethyl)sulfide
3,3'-thiobis-meso-alanine
CROSSLNK Lanthionine (Cys-Ser)
CROSSLNK Lanthionine (Ser-Cys)
XLNK-SCys-(D)3Dha
cysteine-3-D-alanine thioether
meso-lanthionine
(2S,6R)-meso-lanthionine
A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form (2S,3S,2'R)-3-methyllanthionine.
-18.02
C 0 H -2 N 0 O -1 S 0
-18.010565
C 7 H 10 N 2 O 2 S 1
186.23
186.0463
C, T
natural
uniprot.ptm:PTM-0067
(2S,3S)-2-amino-3-([(2R)-2-amino-2-carboxyethyl]sulfanyl)butanoic acid
(2S,3S,2'R)-2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid
(2S,3S,2'R)-3-methyllanthionine
(2S,3S,6R)-2,6-diamino-3-methyl-4-thiaheptanedioic acid
(2S,3S,6R)-3-methyllanthionine
(2S-[2R*,3R*(S*)])-2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid
3-methyl-D,L-lanthionine
CROSSLNK Beta-methyllanthionine (Cys-Thr)
CROSSLNK Beta-methyllanthionine (Thr-Cys)
XLNK-SCys-3Dhb
cysteine-3-D-butyrine thioether
PSI-MOD
MOD:00121
Cross-link 2.
(2S,3S,2'R)-3-methyllanthionine
A protein modification that effectively cross-links an L-cysteine residue and an L-threonine residue by a thioether bond to form (2S,3S,2'R)-3-methyllanthionine.
PubMed:3769923
RESID:AA0112
(2S,3S)-2-amino-3-([(2R)-2-amino-2-carboxyethyl]sulfanyl)butanoic acid
(2S,3S,2'R)-2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid
(2S,3S,2'R)-3-methyllanthionine
(2S,3S,6R)-2,6-diamino-3-methyl-4-thiaheptanedioic acid
(2S,3S,6R)-3-methyllanthionine
(2S-[2R*,3R*(S*)])-2-amino-3-[(2-amino-2-carboxyethyl)thio]butanoic acid
3-methyl-D,L-lanthionine
CROSSLNK Beta-methyllanthionine (Cys-Thr)
CROSSLNK Beta-methyllanthionine (Thr-Cys)
XLNK-SCys-3Dhb
cysteine-3-D-butyrine thioether
A protein modification that effectively cross-links an L-cysteine residue and an L-tyrosine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-tyrosine.
-2.02
C 0 H -2 N 0 O 0 S 0
-2.01565
C 12 H 12 N 2 O 3 S 1
264.3
264.05685
C, Y
natural
uniprot.ptm:PTM-0019
(2S)-2-amino-3-(3-[(2R)2-amino-2-carboxyethylsulfanyl]-4-hydroxyphenyl)propanoic acid
2-amino-3-[3-(2-amino-2-carboxyethylthio)-4-hydroxyphenyl]propanoic acid
3'-(L-cystein-S-yl)-L-tyrosine
3'-(cystein-S-yl)tyrosine
CROSSLNK 3'-(S-cysteinyl)-tyrosine (Cys-Tyr)
CROSSLNK 3'-(S-cysteinyl)-tyrosine (Tyr-Cys)
S-(3-Tyr) (Crosslinked to Cysteine)
S-(tyros-3'-yl)cysteine
XLNK-SCys-3'Tyr
PSI-MOD
MOD:00122
Cross-link 2.
3'-(S-L-cysteinyl)-L-tyrosine
A protein modification that effectively cross-links an L-cysteine residue and an L-tyrosine residue by a thioether bond to form 2-(S-L-cysteinyl)-L-tyrosine.
DeltaMass:0
PubMed:15917234
PubMed:2002850
RESID:AA0113
(2S)-2-amino-3-(3-[(2R)2-amino-2-carboxyethylsulfanyl]-4-hydroxyphenyl)propanoic acid
2-amino-3-[3-(2-amino-2-carboxyethylthio)-4-hydroxyphenyl]propanoic acid
3'-(L-cystein-S-yl)-L-tyrosine
3'-(cystein-S-yl)tyrosine
CROSSLNK 3'-(S-cysteinyl)-tyrosine (Cys-Tyr)
CROSSLNK 3'-(S-cysteinyl)-tyrosine (Tyr-Cys)
S-(3-Tyr) (Crosslinked to Cysteine)
S-(tyros-3'-yl)cysteine
XLNK-SCys-3'Tyr
A protein modification that effectively converts an L-lysine residue to N6-carboxy-L-lysine.
44.01
C 1 H 0 N 0 O 2
43.98983
C 7 H 12 N 2 O 3
172.18
172.0848
K
natural
Unimod:299
uniprot.ptm:PTM-0191
(2S)-2-amino-6-(carboxyamino)hexanoic acid
2-amino-6-carbamic hexanoic acid
MOD_RES N6-carboxylysine
N6-carboxy-L-lysine
N6-carboxylysine
N6CbxLys
lysine NZ-carboxylic acid
PSI-MOD
Carboxy
Carboxylation
N6-carbamyllysine
MOD:00123
N6-carboxy-L-lysine
A protein modification that effectively converts an L-lysine residue to N6-carboxy-L-lysine.
PubMed:11369851
PubMed:4436319
PubMed:637859
PubMed:7754395
RESID:AA0114
Unimod:299#K
(2S)-2-amino-6-(carboxyamino)hexanoic acid
2-amino-6-carbamic hexanoic acid
MOD_RES N6-carboxylysine
N6-carboxy-L-lysine
N6-carboxylysine
N6CbxLys
lysine NZ-carboxylic acid
Carboxy
Carboxylation
N6-carbamyllysine
A protein modification that effectively converts an L-lysine residue to N6-1-carboxyethyl-L-lysine.
72.06
C 3 H 4 N 0 O 2
72.021126
C 9 H 16 N 2 O 3
200.24
200.11609
K
natural
Unimod:378
uniprot.ptm:PTM-0189
(2S)-2-amino-6-([(1S)-1-carboxyethyl]amino)hexanoic acid
MOD_RES N6-1-carboxyethyl lysine
N6-(1-carboxyethyl)-L-lysine
N6-(1-carboxyethyl)lysine
N6CbzEtLys
NZ-(1-carboxyethyl)lysine
PSI-MOD
Carboxyethyl
carboxyethyl
MOD:00124
N6-1-carboxyethyl-L-lysine
A protein modification that effectively converts an L-lysine residue to N6-1-carboxyethyl-L-lysine.
PubMed:3123486
PubMed:8253186
PubMed:8421682
RESID:AA0115
Unimod:378#K
(2S)-2-amino-6-([(1S)-1-carboxyethyl]amino)hexanoic acid
MOD_RES N6-1-carboxyethyl lysine
N6-(1-carboxyethyl)-L-lysine
N6-(1-carboxyethyl)lysine
N6CbzEtLys
NZ-(1-carboxyethyl)lysine
Carboxyethyl
carboxyethyl
A protein modification that effectively converts an L-lysine residue to hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.
87.12
C 4 H 9 N 1 O 1
87.06841
C 10 H 21 N 3 O 2
215.3
215.16338
K
natural
Unimod:379
uniprot.ptm:PTM-0150
(2S)-2-amino-6-([(2R)-4-amino-2-hydroxybutyl]amino)hexanoic acid
(2S,9R)-2,11-diazanyl-9-hydroxy-7-azaundecanoic acid
(2S,9R)-hypusine
2-azanyl-6-[(4-azanyl-2-hydroxybutyl)azanyl]hexanoic acid
Hypu
L-hypusine
MOD_RES Hypusine
N-(4-NH2-2-OH-butyl)- (of Lysine)
N6-(4-amino-2-hydroxybutyl)-L-lysine
PSI-MOD
Hypusine
hypusine
MOD:00125
This modification occurs uniquely in translation initiation factor eIF-5A [JSG].
hypusine
A protein modification that effectively converts an L-lysine residue to hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.
DeltaMass:0
PubMed:6806267
PubMed:8108861
RESID:AA0116
Unimod:379#K
(2S)-2-amino-6-([(2R)-4-amino-2-hydroxybutyl]amino)hexanoic acid
(2S,9R)-2,11-diazanyl-9-hydroxy-7-azaundecanoic acid
(2S,9R)-hypusine
2-azanyl-6-[(4-azanyl-2-hydroxybutyl)azanyl]hexanoic acid
Hypu
L-hypusine
MOD_RES Hypusine
N-(4-NH2-2-OH-butyl)- (of Lysine)
N6-(4-amino-2-hydroxybutyl)-L-lysine
Hypusine
hypusine
A protein modification that effectively converts an L-lysine residue to N6-biotinyl-L-lysine.
226.29
C 10 H 14 N 2 O 2 S 1
226.0776
C 16 H 26 N 4 O 3 S 1
354.47
354.17258
K
natural
Unimod:3
uniprot.ptm:PTM-0382
(2S)-2-amino-6-(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoylamino)hexanoic acid