10:03:2021 14:36 PSI-MOD 1.2 Paul M. Thomas Annotation note 01 - "[PSI-MOD:ref]" has been replaced by PubMed:18688235. Annotation note 02 - When an entry in the RESID Database is annotated with different sources because the same modification can arise from different encoded amino acids, then the PSI-MOD definition for each different source instance carries the RESID cross-reference followed by a hash symbol "#" and a 3 or 4 character label. When an entry in the RESID Database is annotated as a general modification with the same enzymatic activity producing different chemical structures depending on natural variation in the nonproteinaceous substrate, on secondary modifications that do not change the nature of the primary modification, or on a combination of a primary and one or more secondary modifications on the same residue, then the PSI-MOD definition for each different instance carries the RESID cross-reference followed by the special tag "#var". Annotation note 03 - When an entry in the Unimod database is annotated as a general modification, and one or more instance sites are listed, then the PSI-MOD definition for each different site instance carries the Unimod cross-reference followed by a hash symbol and an amino acid code, "N-term" or "C-term". Annotation note 04 - The elemental formulas are in strict alphabetical order, not in CAS ("C" and "H" first) order. Isotope numbers are in parentheses before the element symbol, and an element should not occur in a formula both with and without an isotope number. In difference formulas, counts can be zero or negative. Annotation note 05 - In entries with an isotope indicator in the formula, average masses are meaningless and are assigned the value equal to the monoisotopic mass, but rounded to a lower precision; monoisotopic masses are calculated by using the masses for the indicated isotopes and the most common isotopes for other elements without isotope indicators in the formulas. Annotation note 06 - For cross-link modifications, the number following "Cross-link" in the comment record indicates the number of amino acid residues that appear in the origin record, used to check the difference formula and masses. This usage differs from RESID, where the cross-link number indicates the maximum number of peptide chains that can be cross-linked. Annotation note 07 - The synonym cross-reference "MOD:old name" has been replaced by "MOD:alternate name". Annotation note 08 - The DeltaMass listings for free amino acids have been removed. Most Unimod entries that have not been "approved" have by general agreement not been incorporated unless there has been a request for a specific term by a PRIDE submitter. Annotation note 09 - The Open Mass Spectrometry Search Algorithm, OMSSA, enumerated list of modifications are being incorporated. The string values are synonyms with the synonymtypedef "OMSSA-label", and their integer values (which are supposed to be stable) are definition cross-references. Annotation note 10 - GNOme is the Glycan Naming and Subsumption Ontology (https://gnome.glyomics.org/), an ontology for the support of glycomics. PSI-MOD does not have all possible glycans in its entries, just the ones that are noted to be on proteins and have been requested for addition. GNOme uses GlyTouCan (http://glytoucan.org/) to provide stable accessions for glycans described at varyious degrees of characterization, including compositions (no linkage) and topologies (no carbon bond positions or anomeric configurations). ISO-8601 date: 2021-03-10 14:36Z PSI-MOD version: 1.031.2 RESID release: 75.00 definition Label from MS DeltaMass Short label from OMSSA Alternate name curated by PSI-MOD Short label curated by PSI-MOD subset of protein modifications Agreed label from MS community Alternate name from RESID Misnomer tagged alternate name from RESID Name from RESID Systematic name from RESID Protein feature description from UniProtKB Alternate name from Unimod Description (full_name) from Unimod Interim label from Unimod subset_property synonym_type_property database_cross_reference has_exact_synonym has_obo_format_version has_obo_namespace has_related_synonym has_scope has_synonym_type in_subset 'Entity A' contains 'Entity B' implies that 'Entity B' is a part of the structure of 'Entity A'. PSI-MOD contains The inverse relationship to "part of". contains 'Entity A' contains 'Entity B' implies that 'Entity B' is a part of the structure of 'Entity A'. PubMed:18688235 'Entity A' derives_from 'Entity B' implies that 'Entity A' is chemically derived from 'Entity B'. PSI-MOD derives_from derives from 'Entity A' derives_from 'Entity B' implies that 'Entity A' is chemically derived from 'Entity B'. PubMed:18688235 'Entity A' has_functional_parent 'Entity B' implies that 'Entity B' has at least one chacteristic group from which 'Entity A' can be derived by functional modification. PSI-MOD has_functional_parent This relationship indicates that the formula and mass of the child are not inherited from the mass of the parent. has functional parent 'Entity A' has_functional_parent 'Entity B' implies that 'Entity B' has at least one chacteristic group from which 'Entity A' can be derived by functional modification. PubMed:18688235 'Entity A' part_of 'Entity B' implies that 'Entity A' is a part of the structure of 'Entity B'. PSI-MOD part_of part of 'Entity A' part_of 'Entity B' implies that 'Entity A' is a part of the structure of 'Entity B'. PubMed:18688235 Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue. ModRes PSI-MOD MOD:00000 protein modification Covalent modification of, or a change resulting in an alteration of the measured molecular mass of, a peptide or protein amino acid residue. PubMed:18688235 ModRes A protein modification that effectively replaces a hydrogen atom with an alkyl group. Source: AlkylRes PSI-MOD MOD:00001 alkylated residue A protein modification that effectively replaces a hydrogen atom with an alkyl group. PubMed:18688235 Source: none AlkylRes A protein modification that effectively converts an L-serine residue to O3-glycosylserine. Origin: Source: TermSpec: OGlycoSer PSI-MOD MOD:00002 O-glycosyl-L-serine A protein modification that effectively converts an L-serine residue to O3-glycosylserine. PubMed:18688235 Origin: S Source: natural TermSpec: none OGlycoSer Entry from Unimod. Source: PSI-MOD MOD:00003 This term is for organizational use only and should not be assigned. [JSG] Unimod Entry from Unimod. PubMed:18688235 Source: none Artifact entry from Unimod - OBSOLETE because organizational use is no longer required. PSI-MOD MOD:00004 artifact true Artifact entry from Unimod - OBSOLETE because organizational use is no longer required. PubMed:18688235 A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine. Origin: Source: TermSpec: OGlycoThr PSI-MOD MOD:00005 O-glycosyl-L-threonine A protein modification that effectively converts an L-threonine residue to O3-glycosylthreonine. PubMed:18688235 Origin: T Source: natural TermSpec: none OGlycoThr A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond. Source: NGlycoRes PSI-MOD MOD:00006 N-glycosylated residue A protein modification that effectively replaces a residue hydrogen atom on a nitrogen with a carbohydrate-like group through a glycosidic bond. PubMed:18688235 Source: none NGlycoRes A protein modification that effectively substitutes a selenium atom for a sulfur atom. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: Unimod: Se(S)Res PSI-MOD Delta:S(-1)Se(1) Selenium replaces sulphur MOD:00007 selenium substitution for sulfur A protein modification that effectively substitutes a selenium atom for a sulfur atom. PubMed:12148805 Unimod:162 DiffAvg: 46.91 DiffFormula: C 0 H 0 N 0 O 0 S -1 Se 1 DiffMono: 47.944450 Formula: none MassAvg: none MassMono: none Origin: X Source: natural TermSpec: none Unimod: Unimod:162 Se(S)Res Delta:S(-1)Se(1) Selenium replaces sulphur Entry from Unimod representing one or more entries in RESID. OBSOLETE because organizational use is no longer required. PSI-MOD MOD:00008 common true Entry from Unimod representing one or more entries in RESID. OBSOLETE because organizational use is no longer required. PubMed:18688235 A protein modification that removes a residue, or inserts or replaces a residue with a natural, standard or nonstandard, encoded residue. Origin: Source: Res alpha-amino acid PSI-MOD MOD:00009 natural residue A protein modification that removes a residue, or inserts or replaces a residue with a natural, standard or nonstandard, encoded residue. PubMed:6692818 RESID:AA0000 Origin: X Source: natural Res alpha-amino acid A protein modification that effectively converts a source amino acid residue to an L-alanine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-aminopropanoic acid 2-aminopropionic acid 2-azanylpropanoic acid Ala L-alanine alpha-alanine alpha-aminopropionic acid PSI-MOD MOD:00010 L-alanine residue A protein modification that effectively converts a source amino acid residue to an L-alanine. ChEBI:29948 DeltaMass:0 PubMed:6692818 RESID:AA0001 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 3 H 5 N 1 O 1 MassAvg: 71.08 MassMono: 71.037114 Origin: A Source: natural TermSpec: none (2S)-2-aminopropanoic acid 2-aminopropionic acid 2-azanylpropanoic acid Ala L-alanine alpha-alanine alpha-aminopropionic acid A protein modification that effectively converts a source amino acid residue to an L-arginine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-5-[(diaminomethylidene)amino]pentanoic acid 2-amino-5-(carbamimidamido)pentanoic acid [tautomer] 2-amino-5-[(aminoiminomethyl)amino]pentanoic acid [tautomer] 2-amino-5-guanidinopentanoic acid 2-amino-5-guanidinovaleric acid 2-azanyl-5-[bis(azanyl)methylideneazanyl]pentanoic acid Arg L-arginine alpha-amino-delta-guanidinovaleric acid PSI-MOD MOD:00011 L-arginine residue A protein modification that effectively converts a source amino acid residue to an L-arginine. ChEBI:29952 DeltaMass:0 PubMed:518876 PubMed:6692818 RESID:AA0002 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 6 H 12 N 4 O 1 MassAvg: 156.19 MassMono: 156.101111 Origin: R Source: natural TermSpec: none (2S)-2-amino-5-[(diaminomethylidene)amino]pentanoic acid 2-amino-5-(carbamimidamido)pentanoic acid [tautomer] 2-amino-5-[(aminoiminomethyl)amino]pentanoic acid [tautomer] 2-amino-5-guanidinopentanoic acid 2-amino-5-guanidinovaleric acid 2-azanyl-5-[bis(azanyl)methylideneazanyl]pentanoic acid Arg L-arginine alpha-amino-delta-guanidinovaleric acid A protein modification that effectively converts a source amino acid residue to an L-asparagine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-4-butanediamic acid 2,4-bis(azanyl)-4-oxobutanoic acid 2,4-diamino-4-oxobutanoic acid 2-amino-3-carbamoylpropanoic acid 2-amino-4-butanediamic acid 2-aminosuccinamic acid 2-aminosuccinic acid 4-amide Asn L-asparagine alpha-amino-beta-carbamylpropionic acid alpha-aminosuccinamic acid aspartic acid 4-amide aspartic acid beta-amide beta-asparagine PSI-MOD MOD:00012 L-asparagine residue L-asparagine alpha-amino-beta-carbamylpropionic acid alpha-aminosuccinamic acid aspartic acid 4-amide aspartic acid beta-amide beta-asparagine A protein modification that effectively converts a source amino acid residue to an L-asparagine. ChEBI:29956 DeltaMass:0 PubMed:15736973 PubMed:5681232 PubMed:6692818 PubMed:9789001 RESID:AA0003 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 4 H 6 N 2 O 2 MassAvg: 114.10 MassMono: 114.042927 Origin: N Source: natural TermSpec: none (2S)-2-amino-4-butanediamic acid 2,4-bis(azanyl)-4-oxobutanoic acid 2,4-diamino-4-oxobutanoic acid 2-amino-3-carbamoylpropanoic acid 2-amino-4-butanediamic acid 2-aminosuccinamic acid 2-aminosuccinic acid 4-amide Asn A protein modification that effectively converts a source amino acid residue to an L-aspartic acid. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-aminobutanedioic acid 2-azanylbutanedioic acid Asp L-aspartic acid aminosuccinic acid PSI-MOD MOD:00013 L-aspartic acid residue A protein modification that effectively converts a source amino acid residue to an L-aspartic acid. ChEBI:29958 DeltaMass:0 PubMed:1097438 PubMed:339692 PubMed:4399050 PubMed:5764436 PubMed:6692818 PubMed:8089117 PubMed:9521123 PubMed:9582379 RESID:AA0004 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 4 H 5 N 1 O 3 MassAvg: 115.09 MassMono: 115.026943 Origin: D Source: natural TermSpec: none (2S)-2-aminobutanedioic acid 2-azanylbutanedioic acid Asp L-aspartic acid aminosuccinic acid A protein modification that effectively converts a source amino acid residue to an L-cysteine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2R)-2-amino-3-sulfanylpropanoic acid (R)-cysteine 2-amino-3-mercaptopropanoic acid 2-amino-3-mercaptopropionic acid 2-azanyl-3-sulfanylpropanoic acid 3-mercapto-L-alanine Cys Cysteine (C, Cys) L-(+)-cysteine L-cysteine alpha-amino-beta-mercaptopropanoic acid alpha-amino-beta-mercaptopropionic acid alpha-amino-beta-thiolpropionic acid beta-mercaptoalanine half-cystine thioserine PSI-MOD MOD:00014 From DeltaMass: Average Mass: 121. L-cysteine residue A protein modification that effectively converts a source amino acid residue to an L-cysteine. ChEBI:29950 DeltaMass:0 PubMed:1310545 PubMed:15790858 PubMed:3447159 PubMed:6692818 PubMed:7338899 RESID:AA0005 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 S 0 DiffMono: 0.000000 Formula: C 3 H 5 N 1 O 1 S 1 MassAvg: 103.14 MassMono: 103.009185 Origin: C Source: natural TermSpec: none (2R)-2-amino-3-sulfanylpropanoic acid (R)-cysteine 2-amino-3-mercaptopropanoic acid 2-amino-3-mercaptopropionic acid 2-azanyl-3-sulfanylpropanoic acid 3-mercapto-L-alanine Cys Cysteine (C, Cys) L-(+)-cysteine L-cysteine alpha-amino-beta-mercaptopropanoic acid alpha-amino-beta-mercaptopropionic acid alpha-amino-beta-thiolpropionic acid beta-mercaptoalanine half-cystine thioserine A protein modification that effectively converts a source amino acid residue to an L-glutamic acid. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-aminopentanedioic acid 1-aminopropane-1,3-dicarboxylic acid 2-aminoglutaric acid 2-azanylpentanedioic acid Glu L-glutamic acid alpha-aminoglutaric acid glutaminic acid PSI-MOD MOD:00015 L-glutamic acid residue A protein modification that effectively converts a source amino acid residue to an L-glutamic acid. ChEBI:29972 DeltaMass:0 PubMed:1881881 PubMed:4565668 PubMed:4922541 PubMed:6692818 PubMed:9326660 PubMed:957425 RESID:AA0006 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 5 H 7 N 1 O 3 MassAvg: 129.12 MassMono: 129.042593 Origin: E Source: natural TermSpec: none (2S)-2-aminopentanedioic acid 1-aminopropane-1,3-dicarboxylic acid 2-aminoglutaric acid 2-azanylpentanedioic acid Glu L-glutamic acid alpha-aminoglutaric acid glutaminic acid A protein modification that effectively converts a source amino acid residue to an L-glutamine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-5-pentanediamic acid 2,5-bis(azanyl)-5-oxopentanoic acid 2,5-diamino-5-oxopentanoic acid 2-amino-4-carbamoylbutanoic acid 2-aminoglutaramic acid Gln L-glutamine alpha-amino-gamma-carbamylbutyric acid glutamic acid 5-amide glutamic acid gamma-amide glutamide PSI-MOD MOD:00016 L-glutamine residue A protein modification that effectively converts a source amino acid residue to an L-glutamine. ChEBI:30011 DeltaMass:0 PubMed:3340166 PubMed:6692818 PubMed:9342308 RESID:AA0007 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 5 H 8 N 2 O 2 MassAvg: 128.13 MassMono: 128.058578 Origin: Q Source: natural TermSpec: none (2S)-2-amino-5-pentanediamic acid 2,5-bis(azanyl)-5-oxopentanoic acid 2,5-diamino-5-oxopentanoic acid 2-amino-4-carbamoylbutanoic acid 2-aminoglutaramic acid Gln L-glutamine alpha-amino-gamma-carbamylbutyric acid glutamic acid 5-amide glutamic acid gamma-amide glutamide A protein modification that effectively converts a source amino acid residue to a glycine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: Gly aminoacetic acid aminoethanoic acid azanylethanoic acid glycine glycocoll PSI-MOD MOD:00017 glycine residue A protein modification that effectively converts a source amino acid residue to a glycine. ChEBI:29947 DeltaMass:0 PubMed:1310545 PubMed:6692818 RESID:AA0008 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 2 H 3 N 1 O 1 MassAvg: 57.05 MassMono: 57.021464 Origin: G Source: natural TermSpec: none Gly aminoacetic acid aminoethanoic acid azanylethanoic acid glycine glycocoll A protein modification that effectively converts a source amino acid residue to an L-histidine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid [tautomer] 2-azanyl-3-(1H-imidazol-4-yl)propanoic acid 2-azanyl-3-(1H-imidazol-5-yl)propanoic acid [tautomer] 4-(2-amino-2-carboxyethyl)imidazole His L-histidine alpha-amino-beta-(4-imidazole)propionic acid glyoxaline-5-alanine PSI-MOD MOD:00018 L-histidine residue A protein modification that effectively converts a source amino acid residue to an L-histidine. ChEBI:29979 DeltaMass:0 PubMed:14342316 PubMed:2722967 PubMed:512 PubMed:5460889 PubMed:6129252 PubMed:6692818 PubMed:6876174 RESID:AA0009 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 6 H 7 N 3 O 1 MassAvg: 137.14 MassMono: 137.058912 Origin: H Source: natural TermSpec: none (2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid [tautomer] 2-azanyl-3-(1H-imidazol-4-yl)propanoic acid 2-azanyl-3-(1H-imidazol-5-yl)propanoic acid [tautomer] 4-(2-amino-2-carboxyethyl)imidazole His L-histidine alpha-amino-beta-(4-imidazole)propionic acid glyoxaline-5-alanine A protein modification that effectively converts a source amino acid residue to an L-isoleucine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S,3S)-2-amino-3-methylpentanoic acid 2-azanyl-3-methylpentanoic acid 3-methyl-norvaline Ile Isoleucyl L-erythro-isoleucine L-isoleucine alpha-amino-beta-methylvaleric acid PSI-MOD MOD:00019 L-isoleucine residue A protein modification that effectively converts a source amino acid residue to an L-isoleucine. ChEBI:30009 DeltaMass:0 PubMed:6692818 RESID:AA0010 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 6 H 11 N 1 O 1 MassAvg: 113.16 MassMono: 113.084064 Origin: I Source: natural TermSpec: none (2S,3S)-2-amino-3-methylpentanoic acid 2-azanyl-3-methylpentanoic acid 3-methyl-norvaline Ile Isoleucyl L-erythro-isoleucine L-isoleucine alpha-amino-beta-methylvaleric acid A protein modification that effectively converts a source amino acid residue to an L-leucine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-4-methylpentanoic acid 2-azanyl-4-methylpentanoic acid 4-methyl-norvaline L-leucine Leu alpha-amino-gamma-methylvaleric acid alpha-aminoisocaproic acid PSI-MOD MOD:00020 L-leucine residue A protein modification that effectively converts a source amino acid residue to an L-leucine. ChEBI:30006 DeltaMass:0 PubMed:11478885 PubMed:6692818 RESID:AA0011 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 6 H 11 N 1 O 1 MassAvg: 113.16 MassMono: 113.084064 Origin: L Source: natural TermSpec: none (2S)-2-amino-4-methylpentanoic acid 2-azanyl-4-methylpentanoic acid 4-methyl-norvaline L-leucine Leu alpha-amino-gamma-methylvaleric acid alpha-aminoisocaproic acid A protein modification that effectively converts a source amino acid residue to L-lysine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2,6-diaminohexanoic acid 2,6-bis(azanyl)hexanoic acid 6-amino-L-norleucine ACT_SITE Schiff-base intermediate with substrate L-lysine Lys alpha,epsilon-diaminocaproic acid PSI-MOD MOD:00021 L-lysine residue A protein modification that effectively converts a source amino acid residue to L-lysine. ChEBI:29967 DeltaMass:0 PubMed:3106962 PubMed:6120171 PubMed:6692818 RESID:AA0012 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 6 H 12 N 2 O 1 MassAvg: 128.18 MassMono: 128.094963 Origin: K Source: natural TermSpec: none (2S)-2,6-diaminohexanoic acid 2,6-bis(azanyl)hexanoic acid 6-amino-L-norleucine ACT_SITE Schiff-base intermediate with substrate L-lysine Lys alpha,epsilon-diaminocaproic acid A protein modification that effectively converts a source amino acid residue to L-methionine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-4-(methylsulfanyl)butanoic acid 2-amino-4-(methylthio)butanoic acid 2-amino-4-(methylthio)butyric acid 2-azanyl-4-(methylsulfanyl)butanoic acid L-(-)-methionine L-methionine Met S-methyl-L-homocysteine alpha-amino-gamma-methylmercaptobutyric acid alpha-amino-gamma-methylthiobutyric acid gamma-methylthio-alpha-aminobutyric acid PSI-MOD MOD:00022 From DeltaMass: Average Mass: 149 L-methionine residue A protein modification that effectively converts a source amino acid residue to L-methionine. ChEBI:29983 DeltaMass:0 PubMed:6411710 PubMed:6692818 RESID:AA0013 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 S 0 DiffMono: 0.000000 Formula: C 5 H 9 N 1 O 1 S 1 MassAvg: 131.19 MassMono: 131.040485 Origin: M Source: natural TermSpec: none (2S)-2-amino-4-(methylsulfanyl)butanoic acid 2-amino-4-(methylthio)butanoic acid 2-amino-4-(methylthio)butyric acid 2-azanyl-4-(methylsulfanyl)butanoic acid L-(-)-methionine L-methionine Met S-methyl-L-homocysteine alpha-amino-gamma-methylmercaptobutyric acid alpha-amino-gamma-methylthiobutyric acid gamma-methylthio-alpha-aminobutyric acid A protein modification that effectively converts a source amino acid residue to L-phenylalanine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-3-phenylpropanoic acid 2-azanyl-3-phenylpropanoic acid L-phenylalanine Phe alpha-amino-beta-phenylpropionic acid PSI-MOD MOD:00023 L-phenylalanine residue A protein modification that effectively converts a source amino acid residue to L-phenylalanine. ChEBI:29997 DeltaMass:0 PubMed:6692818 RESID:AA0014 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 9 H 9 N 1 O 1 MassAvg: 147.18 MassMono: 147.068414 Origin: F Source: natural TermSpec: none (2S)-2-amino-3-phenylpropanoic acid 2-azanyl-3-phenylpropanoic acid L-phenylalanine Phe alpha-amino-beta-phenylpropionic acid A protein modification that effectively converts a source amino acid residue to L-proline. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-pyrrolidinecarboxylic acid L-proline Pro pyrrolidine-2-carboxylic acid PSI-MOD MOD:00024 L-proline residue A protein modification that effectively converts a source amino acid residue to L-proline. ChEBI:30017 DeltaMass:0 PubMed:6692818 PubMed:8547259 RESID:AA0015 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 5 H 7 N 1 O 1 MassAvg: 97.12 MassMono: 97.052764 Origin: P Source: natural TermSpec: none (2S)-2-pyrrolidinecarboxylic acid L-proline Pro pyrrolidine-2-carboxylic acid A protein modification that effectively converts a source amino acid residue to L-serine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-3-hydroxypropanoic acid 2-azanyl-3-hydroxypropanoic acid 3-hydroxy-L-alanine L-serine Ser alpha-amino-beta-hydroxypropionic acid beta-hydroxyalanine PSI-MOD MOD:00025 L-serine residue A protein modification that effectively converts a source amino acid residue to L-serine. ChEBI:29999 DeltaMass:0 PubMed:4399050 PubMed:6692818 RESID:AA0016 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 3 H 5 N 1 O 2 MassAvg: 87.08 MassMono: 87.032028 Origin: S Source: natural TermSpec: none (2S)-2-amino-3-hydroxypropanoic acid 2-azanyl-3-hydroxypropanoic acid 3-hydroxy-L-alanine L-serine Ser alpha-amino-beta-hydroxypropionic acid beta-hydroxyalanine A protein modification that effectively converts a source amino acid residue to L-threonine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S,3R)-2-amino-3-hydroxybutanoic acid 2-azanyl-3-hydroxybutanoic acid L-threo-threonine L-threonine Thr alpha-amino-beta-hydroxybutyric acid beta-methylserine PSI-MOD MOD:00026 L-threonine residue A protein modification that effectively converts a source amino acid residue to L-threonine. ChEBI:30013 DeltaMass:0 PubMed:2989287 PubMed:6692818 RESID:AA0017 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 4 H 7 N 1 O 2 MassAvg: 101.10 MassMono: 101.047678 Origin: T Source: natural TermSpec: none (2S,3R)-2-amino-3-hydroxybutanoic acid 2-azanyl-3-hydroxybutanoic acid L-threo-threonine L-threonine Thr alpha-amino-beta-hydroxybutyric acid beta-methylserine A protein modification that effectively converts a source amino acid residue to L-tryptophan. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid 2-azanyl-3-(1H-indol-3-yl)propanoic acid L-tryptophan Trp alpha-amino-beta-(3-indolyl)propionoic acid beta(3-indolyl)alanine PSI-MOD MOD:00027 L-tryptophan residue A protein modification that effectively converts a source amino acid residue to L-tryptophan. ChEBI:29954 DeltaMass:0 PubMed:2059637 PubMed:6692818 PubMed:9324768 RESID:AA0018 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 11 H 10 N 2 O 1 MassAvg: 186.21 MassMono: 186.079313 Origin: W Source: natural TermSpec: none (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid 2-azanyl-3-(1H-indol-3-yl)propanoic acid L-tryptophan Trp alpha-amino-beta-(3-indolyl)propionoic acid beta(3-indolyl)alanine A protein modification that effectively converts a source amino acid residue to L-tyrosine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-3-(4-hydoxyphenyl)propanoic acid 2-azanyl-3-(4-hydoxyphenyl)propanoic acid L-tyrosine Tyr alpha-amino-beta-(para-hydroxyphenyl)propionic acid p-tyrosine para-hydroxyphenylalanine PSI-MOD MOD:00028 L-tyrosine residue A protein modification that effectively converts a source amino acid residue to L-tyrosine. ChEBI:29975 DeltaMass:0 PubMed:2190093 PubMed:2542938 PubMed:5550972 PubMed:6061414 PubMed:6120171 PubMed:6692818 RESID:AA0019 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 9 H 9 N 1 O 2 MassAvg: 163.18 MassMono: 163.063329 Origin: Y Source: natural TermSpec: none (2S)-2-amino-3-(4-hydoxyphenyl)propanoic acid 2-azanyl-3-(4-hydoxyphenyl)propanoic acid L-tyrosine Tyr alpha-amino-beta-(para-hydroxyphenyl)propionic acid p-tyrosine para-hydroxyphenylalanine A protein modification that effectively converts a source amino acid residue to an L-valine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-amino-3-methylbutanoic acid 2-azanyl-3-methylbutanoic acid L-valine Val alpha-amino-beta-methylbutyric acid alpha-aminoisovaleric acid PSI-MOD MOD:00029 L-valine residue A protein modification that effectively converts a source amino acid residue to an L-valine. ChEBI:30015 DeltaMass:0 PubMed:6692818 RESID:AA0020 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 DiffMono: 0.000000 Formula: C 5 H 9 N 1 O 1 MassAvg: 99.13 MassMono: 99.068414 Origin: V Source: natural TermSpec: none (2S)-2-amino-3-methylbutanoic acid 2-azanyl-3-methylbutanoic acid L-valine Val alpha-amino-beta-methylbutyric acid alpha-aminoisovaleric acid A protein modification that effectively converts a source amino acid residue to an N-formyl-L-methionine, a natural pretranslational modification. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-formylamino-4-(methylsulfanyl)butanoic acid 2-formamido-4-(methylsulfanyl)butanoic acid 2-formylamino-4-(methylthio)butanoic acid 2-formylazanyl-4-(methylsulfanyl)butanoic acid MOD_RES N-formylmethionine N-formyl-L-methionine N-formylated L-methionine fMet nformylmet PSI-MOD FormylMet MOD:00030 N-formyl-L-methionine residue A protein modification that effectively converts a source amino acid residue to an N-formyl-L-methionine, a natural pretranslational modification. ChEBI:33718 OMSSA:22 PubMed:10825024 PubMed:11152118 PubMed:2165784 PubMed:3042771 PubMed:8758896 RESID:AA0021#FMET DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 S 0 DiffMono: 0.000000 Formula: C 6 H 10 N 1 O 2 S 1 MassAvg: 160.21 MassMono: 160.043225 Origin: M Source: natural TermSpec: N-term (2S)-2-formylamino-4-(methylsulfanyl)butanoic acid 2-formamido-4-(methylsulfanyl)butanoic acid 2-formylamino-4-(methylthio)butanoic acid 2-formylazanyl-4-(methylsulfanyl)butanoic acid MOD_RES N-formylmethionine N-formyl-L-methionine N-formylated L-methionine fMet nformylmet FormylMet A protein modification that effectively converts a source amino acid residue to an L-selenocysteine, a natural pretranslational modification. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2R)-2-amino-3-selanylpropanoic acid 2-azanyl-3-selanylpropanoic acid 3-selenylalanine L-selenocysteine NON_STD Selenocysteine SeCys Sec selenium cysteine PSI-MOD MOD:00031 L-selenocysteine residue A protein modification that effectively converts a source amino acid residue to an L-selenocysteine, a natural pretranslational modification. ChEBI:30000 PubMed:10523135 PubMed:1066676 PubMed:2037562 PubMed:2963330 PubMed:4734725 PubMed:6076213 PubMed:6217842 PubMed:6714945 RESID:AA0022 DiffAvg: 0.00 DiffFormula: C 0 H 0 N 0 O 0 Se 0 DiffMono: 0.000000 Formula: C 3 H 5 N 1 O 1 Se 1 MassAvg: 150.05 MassMono: 150.953635 Origin: U Source: natural TermSpec: none (2R)-2-amino-3-selanylpropanoic acid 2-azanyl-3-selanylpropanoic acid 3-selenylalanine L-selenocysteine NON_STD Selenocysteine SeCys Sec selenium cysteine A protein modification that is not chemically categorized. Source: PSI-MOD MOD:00032 This term is for organizational use only and should not be assigned. [JSG] uncategorized protein modification A protein modification that is not chemically categorized. PubMed:18688235 Source: none A protein modification that crosslinks two or more amino acid residues with covalent bonds. Source: XLNK-Res-Res PSI-MOD MOD:00033 The covalent bond is formed directly between sidechain atoms. If non-aminoacid atoms are involved in connecting two or more peptide chain residues peptide chain, the connection is classified as a multivalent binding site. crosslinked residues A protein modification that crosslinks two or more amino acid residues with covalent bonds. PubMed:18688235 Source: none XLNK-Res-Res A protein modification that effectively cross-links two L-cysteine residues to form L-cystine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2R,2'R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid) 3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid) 3,3'-dithiobis(2-aminopropanoic acid) 3,3'-dithiobisalanine 3,3'-dithiodialanine Cys2 Cystine ((Cys)2) DISULFID DISULFID Interchain L-cystine XLNK-SCys-SCys beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfide beta,beta'-dithiodialanine bis(alpha-aminopropionic acid)-beta-disulfide bis(beta-amino-beta-carboxyethyl)disulfide dicysteine PSI-MOD 2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid MOD:00034 Cross-link 2; for formation of a disulfide bond between a peptide cysteine and a free cysteine, see MOD:00765. L-cystine (cross-link) A protein modification that effectively cross-links two L-cysteine residues to form L-cystine. ChEBI:16283 DeltaMass:0 PubMed:1988019 PubMed:2001356 PubMed:2076469 PubMed:3083866 PubMed:366603 PubMed:7918467 PubMed:8344916 RESID:AA0025#CYS2 DiffAvg: -2.02 DiffFormula: C 0 H -2 N 0 O 0 S 0 DiffMono: -2.015650 Formula: C 6 H 8 N 2 O 2 S 2 MassAvg: 204.26 MassMono: 204.002720 Origin: C, C Source: natural TermSpec: none (2R,2'R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid) 3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid) 3,3'-dithiobis(2-aminopropanoic acid) 3,3'-dithiobisalanine 3,3'-dithiodialanine Cys2 Cystine ((Cys)2) DISULFID DISULFID Interchain L-cystine XLNK-SCys-SCys beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfide beta,beta'-dithiodialanine bis(alpha-aminopropionic acid)-beta-disulfide bis(beta-amino-beta-carboxyethyl)disulfide dicysteine 2-amino-3-(2-amino-2-carboxy-ethyl)disulfanyl-propanoic acid A protein modification that effectively converts an L-asparagine residue to (2S,3R)-3-hydroxyasparagine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S,3R)-2,4-diamino-3-hydroxy-4-oxobutanoic acid (2S,3R)-2-amino-3-hydroxy-4-butanediamic acid (2S,3R)-3-hydroxyasparagine (3R)3HyAsn 2-azanyl-3-hydroxy-4-butanediamic acid L-erythro-beta-hydroxyasparagine MOD_RES (3R)-3-hydroxyasparagine erythro-beta-hydroxylated L-asparagine PSI-MOD MOD:00035 (2S,3R)-3-hydroxyasparagine A protein modification that effectively converts an L-asparagine residue to (2S,3R)-3-hydroxyasparagine. ChEBI:141853 PubMed:11823643 PubMed:2820791 RESID:AA0026 DiffAvg: 16.00 DiffFormula: C 0 H 0 N 0 O 1 DiffMono: 15.994915 Formula: C 4 H 6 N 2 O 3 MassAvg: 130.10 MassMono: 130.037842 Origin: N Source: natural TermSpec: none UniProt: PTM-0369 (2S,3R)-2,4-diamino-3-hydroxy-4-oxobutanoic acid (2S,3R)-2-amino-3-hydroxy-4-butanediamic acid (2S,3R)-3-hydroxyasparagine (3R)3HyAsn 2-azanyl-3-hydroxy-4-butanediamic acid L-erythro-beta-hydroxyasparagine MOD_RES (3R)-3-hydroxyasparagine erythro-beta-hydroxylated L-asparagine A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S,3R)-2-amino-3-hydroxybutanedioic acid (2S,3R)-3-hydroxyaspartic acid (3R)3HyAsp 2-amino-3-hydroxysuccinic acid 2-azanyl-3-hydroxybutanedioic acid 3-hydroxyaspartic acid L-erythro-beta-hydroxyaspartic acid MOD_RES (3R)-3-hydroxyaspartate erythro-beta-hydroxylated L-aspartic acid hydroxylationd PSI-MOD Oxidation MOD:00036 (2S,3R)-3-hydroxyaspartic acid A protein modification that effectively converts an L-aspartic acid residue to (2S,3R)-3-hydroxyaspartic acid. ChEBI:141848 OMSSA:59 PubMed:6572939 PubMed:6871167 PubMed:8355279 RESID:AA0027 Unimod:35#D DiffAvg: 16.00 DiffFormula: C 0 H 0 N 0 O 1 DiffMono: 15.994915 Formula: C 4 H 5 N 1 O 4 MassAvg: 131.09 MassMono: 131.021858 Origin: D Source: natural TermSpec: none UniProt: PTM-0371 Unimod: Unimod:35 (2S,3R)-2-amino-3-hydroxybutanedioic acid (2S,3R)-3-hydroxyaspartic acid (3R)3HyAsp 2-amino-3-hydroxysuccinic acid 2-azanyl-3-hydroxybutanedioic acid 3-hydroxyaspartic acid L-erythro-beta-hydroxyaspartic acid MOD_RES (3R)-3-hydroxyaspartate erythro-beta-hydroxylated L-aspartic acid hydroxylationd Oxidation A protein modification that effectively converts an L-lysine residue to one of the diastereomeric 5-hydroxy-L-lysine residues. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: 5-hydroxylated L-lysine 5HyLys PSI-MOD MOD:00037 5-hydroxy-L-lysine A protein modification that effectively converts an L-lysine residue to one of the diastereomeric 5-hydroxy-L-lysine residues. ChEBI:60175 PubMed:18688235 DiffAvg: 16.00 DiffFormula: C 0 H 0 N 0 O 1 DiffMono: 15.994915 Formula: C 6 H 12 N 2 O 2 MassAvg: 144.17 MassMono: 144.089878 Origin: K Source: natural TermSpec: none UniProt: PTM-0044 5-hydroxylated L-lysine 5HyLys A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid 3-hydroxy-L-proline 3-hydroxylated L-proline 3-trans-hydroxy-L-proline 3HyPro L-threo-3-hydroxyproline MOD_RES 3-hydroxyproline beta-hydroxypyrrolidine-alpha-carboxylic acid PSI-MOD MOD:00038 3-hydroxy-L-proline A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline. ChEBI:16889 PubMed:2400108 PubMed:3734192 PubMed:4343807 RESID:AA0029 DiffAvg: 16.00 DiffFormula: C 0 H 0 N 0 O 1 DiffMono: 15.994915 Formula: C 5 H 7 N 1 O 2 MassAvg: 113.12 MassMono: 113.047678 Origin: P Source: natural TermSpec: none UniProt: PTM-0030 (2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid 3-hydroxy-L-proline 3-hydroxylated L-proline 3-trans-hydroxy-L-proline 3HyPro L-threo-3-hydroxyproline MOD_RES 3-hydroxyproline beta-hydroxypyrrolidine-alpha-carboxylic acid A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid 4-hydroxy-L-proline 4-hydroxylated L-proline 4-hydroxyproline 4-trans-hydroxy-L-proline 4HyPro L-threo-4-hydroxyproline MOD_RES 4-hydroxyproline gamma-hydroxypyrrolidine-alpha-carboxylic acid PSI-MOD MOD:00039 4-hydroxy-L-proline A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline ChEBI:18095 PubMed:11292863 PubMed:2400108 PubMed:3734192 RESID:AA0030 DiffAvg: 16.00 DiffFormula: C 0 H 0 N 0 O 1 DiffMono: 15.994915 Formula: C 5 H 7 N 1 O 2 MassAvg: 113.12 MassMono: 113.047678 Origin: P Source: natural TermSpec: none UniProt: PTM-0043 (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid 4-hydroxy-L-proline 4-hydroxylated L-proline 4-hydroxyproline 4-trans-hydroxy-L-proline 4HyPro L-threo-4-hydroxyproline MOD_RES 4-hydroxyproline gamma-hydroxypyrrolidine-alpha-carboxylic acid A protein modification that effectively converts an L-glutamine residue to 2-pyrrolidone-5-carboxylic acid. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-5-oxo-2-pyrrolidinecarboxylic acid 2-oxopyrrolidine-5-carboxylic acid 2-pyrrolidone-5-carboxylic acid 5-oxoproline 5-oxopyrrolidine-2-carboxylic acid 5-pyrrolidone-2-carboxylic acid MOD_RES Pyrrolidone carboxylic acid N-pyrrolidone carboxyl (N terminus) PCA PyrGlu(Gln) Pyroglutamic Acid formed from Gln Pyroglutamyl ntermpeppyroq pyroglutamic acid PSI-MOD Gln->pyro-Glu Pyro-glu from Q MOD:00040 DeltaMass gives a formula C 5 H 5 N 1 O 2 with mass 111.1 2-pyrrolidone-5-carboxylic acid (Gln) A protein modification that effectively converts an L-glutamine residue to 2-pyrrolidone-5-carboxylic acid. ChEBI:30652 DeltaMass:123 OMSSA:110 PubMed:10214721 PubMed:1836357 PubMed:26343 PubMed:3473473 RESID:AA0031#GLN Unimod:28#Q DiffAvg: -17.03 DiffFormula: C 0 H -3 N -1 O 0 DiffMono: -17.026549 Formula: C 5 H 6 N 1 O 2 MassAvg: 112.11 MassMono: 112.039853 Origin: Q Source: natural TermSpec: N-term UniProt: PTM-0261 Unimod: Unimod:28 (2S)-5-oxo-2-pyrrolidinecarboxylic acid 2-oxopyrrolidine-5-carboxylic acid 2-pyrrolidone-5-carboxylic acid 5-oxoproline 5-oxopyrrolidine-2-carboxylic acid 5-pyrrolidone-2-carboxylic acid MOD_RES Pyrrolidone carboxylic acid N-pyrrolidone carboxyl (N terminus) PCA PyrGlu(Gln) Pyroglutamic Acid formed from Gln Pyroglutamyl ntermpeppyroq pyroglutamic acid Gln->pyro-Glu Pyro-glu from Q A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (3S)-3-aminopropane-1,1,3-tricarboxylic acid (3S)-3-azanylpropane-1,1,3-tricarboxylic acid 3-amino-1,1,3-propanetricarboxylic acid 3-azanylpropane-1,1,3-tricarboxylic acid 4-carboxyglutamic acid 4CbxGlu Carboxy Glutamyl L-gamma-carboxyglutamic acid MOD_RES 4-carboxyglutamate gamma-carboxylated L-glutamic acid gammacarboxyle PSI-MOD 1-carboxyglutamic acid Carboxy Carboxylation MOD:00041 DeltaMass has an incorrect formula C 6 H 7 N 5 O 1 (N and O reversed) with mass 173. L-gamma-carboxyglutamic acid A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid. DeltaMass:217 OMSSA:48 PubMed:10517147 PubMed:1807167 PubMed:3263814 PubMed:4528109 PubMed:7457858 PubMed:8135347 PubMed:8868490 PubMed:9188685 RESID:AA0032 Unimod:299#E DiffAvg: 44.01 DiffFormula: C 1 H 0 N 0 O 2 DiffMono: 43.989829 Formula: C 6 H 7 N 1 O 5 MassAvg: 173.12 MassMono: 173.032422 Origin: E Source: natural TermSpec: none UniProt: PTM-0039 Unimod: Unimod:299 (3S)-3-aminopropane-1,1,3-tricarboxylic acid (3S)-3-azanylpropane-1,1,3-tricarboxylic acid 3-amino-1,1,3-propanetricarboxylic acid 3-azanylpropane-1,1,3-tricarboxylic acid 4-carboxyglutamic acid 4CbxGlu Carboxy Glutamyl L-gamma-carboxyglutamic acid MOD_RES 4-carboxyglutamate gamma-carboxylated L-glutamic acid gammacarboxyle 1-carboxyglutamic acid Carboxy Carboxy Carboxylation A protein modification that effectively converts an L-aspartic acid residue to L-aspartic 4-phosphoric anhydride. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-4-oxo-4-(phosphonooxy)butanoic acid 2-aminobutanedioic 4-phosphoric anhydride 2-azanyl-4-oxo-4-(phosphonooxy)butanoic acid 4-oxo-O-phosphono-L-homoserine 4-phosphoaspartic acid 4-phosphorylated L-aspartatic acid ACT_SITE 4-aspartylphosphate intermediate L-aspartic 4-phosphoric anhydride MOD_RES 4-aspartylphosphate PAsp beta-aspartyl phosphate PSI-MOD Phospho Phosphorylation MOD:00042 L-aspartic 4-phosphoric anhydride A protein modification that effectively converts an L-aspartic acid residue to L-aspartic 4-phosphoric anhydride. ChEBI:15836 PubMed:4357737 RESID:AA0033 Unimod:21#D DiffAvg: 79.98 DiffFormula: C 0 H 1 N 0 O 3 P 1 DiffMono: 79.966331 Formula: C 4 H 6 N 1 O 6 P 1 MassAvg: 195.07 MassMono: 194.993274 Origin: D Source: natural TermSpec: none UniProt: PTM-0038 Unimod: Unimod:21 (2S)-2-amino-4-oxo-4-(phosphonooxy)butanoic acid 2-aminobutanedioic 4-phosphoric anhydride 2-azanyl-4-oxo-4-(phosphonooxy)butanoic acid 4-oxo-O-phosphono-L-homoserine 4-phosphoaspartic acid 4-phosphorylated L-aspartatic acid ACT_SITE 4-aspartylphosphate intermediate L-aspartic 4-phosphoric anhydride MOD_RES 4-aspartylphosphate PAsp beta-aspartyl phosphate Phospho Phosphorylation A protein modification that effectively converts an L-cysteine residue to S-phospho-L-cysteine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2R)-2-amino-3-(phosphonosulfanyl)propanoic acid 2-azanyl-3-(phosphonosulfanyl)propanoic acid ACT_SITE Phosphocysteine intermediate MOD_RES Phosphocysteine PCys S-phospho-L-cysteine S-phosphonocysteine S-phosphorylated L-cysteine S3-phosphocysteine cysteine phosphate thioester PSI-MOD Phospho Phosphorylation MOD:00043 S-phospho-L-cysteine A protein modification that effectively converts an L-cysteine residue to S-phospho-L-cysteine. PubMed:3142516 PubMed:7961745 PubMed:8128219 RESID:AA0034 Unimod:21#C DiffAvg: 79.98 DiffFormula: C 0 H 1 N 0 O 3 P 1 S 0 DiffMono: 79.966331 Formula: C 3 H 6 N 1 O 4 P 1 S 1 MassAvg: 183.12 MassMono: 182.975515 Origin: C Source: natural TermSpec: none UniProt: PTM-0251 Unimod: Unimod:21 (2R)-2-amino-3-(phosphonosulfanyl)propanoic acid 2-azanyl-3-(phosphonosulfanyl)propanoic acid ACT_SITE Phosphocysteine intermediate MOD_RES Phosphocysteine PCys S-phospho-L-cysteine S-phosphonocysteine S-phosphorylated L-cysteine S3-phosphocysteine cysteine phosphate thioester Phospho Phosphorylation A protein modification that effectively converts an L-histidine residue to tele-phospho-L-histidine (N-tau-phospho-L-histidine, 1'-phospho-L-histidine). DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-amino-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid 1'-phospho-L-histidine 2-azanyl-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid ACT_SITE Tele-phosphohistidine intermediate MOD_RES Tele-phosphohistidine N(tau)-phosphohistidine N1-phosphonohistidine NE2-phosphonohistidine NtPHis Ntau-phosphorylated L-histidine histidine-N(epsilon)-phosphate histidine-N1'-phosphate tele-phosphohistidine PSI-MOD Phospho Phosphorylation histidine-3-phosphate MOD:00044 1'-phospho-L-histidine A protein modification that effectively converts an L-histidine residue to tele-phospho-L-histidine (N-tau-phospho-L-histidine, 1'-phospho-L-histidine). PubMed:11038361 PubMed:5642389 PubMed:6692818 RESID:AA0035 DiffAvg: 79.98 DiffFormula: C 0 H 1 N 0 O 3 P 1 DiffMono: 79.966331 Formula: C 6 H 8 N 3 O 4 P 1 MassAvg: 217.12 MassMono: 217.025242 Origin: H Source: natural TermSpec: none UniProt: PTM-0325 (2S)-2-amino-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid 1'-phospho-L-histidine 2-azanyl-3-(1-phosphono-1H-imidazol-4-yl)propanoic acid ACT_SITE Tele-phosphohistidine intermediate MOD_RES Tele-phosphohistidine N(tau)-phosphohistidine N1-phosphonohistidine NE2-phosphonohistidine NtPHis Ntau-phosphorylated L-histidine histidine-N(epsilon)-phosphate histidine-N1'-phosphate tele-phosphohistidine Phospho Phosphorylation histidine-3-phosphate A protein modification that effectively converts an L-histidine residue to pros-phospho-L-histidine (N-pi-phospho-L-histidine, 3'-phospho-L-histidine). DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-amino-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid 2-azanyl-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid 3'-phospho-L-histidine ACT_SITE Pros-phosphohistidine intermediate MOD_RES Pros-phosphohistidine N(pi)-phosphohistidine N3-phosphonohistidine ND1-phosphonohistidine NpPHis Npi-phosphorylated L-histidine histidine-N(delta)-phosphate histidine-N3'-phosphate pros-phosphohistidine PSI-MOD Phospho Phosphorylation histidine-1-phosphate MOD:00045 3'-phospho-L-histidine A protein modification that effectively converts an L-histidine residue to pros-phospho-L-histidine (N-pi-phospho-L-histidine, 3'-phospho-L-histidine). PubMed:1549615 PubMed:5642389 PubMed:6692818 PubMed:7669763 PubMed:7803390 RESID:AA0036 DiffAvg: 79.98 DiffFormula: C 0 H 1 N 0 O 3 P 1 DiffMono: 79.966331 Formula: C 6 H 8 N 3 O 4 P 1 MassAvg: 217.12 MassMono: 217.025242 Origin: H Source: natural TermSpec: none UniProt: PTM-0260 (2S)-2-amino-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid 2-azanyl-3-(3-phosphono-3H-imidazol-4-yl)propanoic acid 3'-phospho-L-histidine ACT_SITE Pros-phosphohistidine intermediate MOD_RES Pros-phosphohistidine N(pi)-phosphohistidine N3-phosphonohistidine ND1-phosphonohistidine NpPHis Npi-phosphorylated L-histidine histidine-N(delta)-phosphate histidine-N3'-phosphate pros-phosphohistidine Phospho Phosphorylation histidine-1-phosphate A protein modification that effectively converts an L-serine residue to O-phospho-L-serine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine OPSer Phospho Seryl phosphorylations serine phosphate ester PSI-MOD Phospho Phosphorylation MOD:00046 O-phospho-L-serine A protein modification that effectively converts an L-serine residue to O-phospho-L-serine. ChEBI:15811 DeltaMass:0 OMSSA:6 PubMed:12923550 PubMed:4065410 PubMed:8061611 RESID:AA0037 Unimod:21#S DiffAvg: 79.98 DiffFormula: C 0 H 1 N 0 O 3 P 1 DiffMono: 79.966331 Formula: C 3 H 6 N 1 O 5 P 1 MassAvg: 167.06 MassMono: 166.998359 Origin: S Source: natural TermSpec: none UniProt: PTM-0253 Unimod: Unimod:21 (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine OPSer Phospho Seryl phosphorylations serine phosphate ester Phospho Phosphorylation A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S,3R)-2-amino-3-(phosphonooxy)butanoic acid 2-amino-3-hydroxybutanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)butanoic acid MOD_RES Phosphothreonine O-phospho-L-threonine O-phosphorylated L-threonine O3-phosphothreonine OPThr Phospho Threonyl phosphorylationt threonine phosphate ester PSI-MOD Phospho Phosphorylation MOD:00047 O-phospho-L-threonine A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine. ChEBI:21967 DeltaMass:0 OMSSA:7 PubMed:12923550 PubMed:7678926 RESID:AA0038 Unimod:21#T DiffAvg: 79.98 DiffFormula: C 0 H 1 N 0 O 3 P 1 DiffMono: 79.966331 Formula: C 4 H 8 N 1 O 5 P 1 MassAvg: 181.08 MassMono: 181.014009 Origin: T Source: natural TermSpec: none UniProt: PTM-0254 Unimod: Unimod:21 (2S,3R)-2-amino-3-(phosphonooxy)butanoic acid 2-amino-3-hydroxybutanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)butanoic acid MOD_RES Phosphothreonine O-phospho-L-threonine O-phosphorylated L-threonine O3-phosphothreonine OPThr Phospho Threonyl phosphorylationt threonine phosphate ester Phospho Phosphorylation A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid 2-amino-3-(4-hydroxyphenyl)propanoic acid 4'-phosphate 2-azanyl-3-(4-phosphonooxyphenyl)propanoic acid MOD_RES Phosphotyrosine O4'-phospho-L-tyrosine O4'-phosphorylated L-tyrosine O4-phosphotyrosine OPTyr Phospho Tyrosinyl phosphorylationy tyrosine phosphate PSI-MOD Phospho Phosphorylation MOD:00048 O4'-phospho-L-tyrosine A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine. DeltaMass:0 OMSSA:8 PubMed:10226369 PubMed:1725475 RESID:AA0039 Unimod:21#Y DiffAvg: 79.98 DiffFormula: C 0 H 1 N 0 O 3 P 1 DiffMono: 79.966331 Formula: C 9 H 10 N 1 O 5 P 1 MassAvg: 243.15 MassMono: 243.029659 Origin: Y Source: natural TermSpec: none UniProt: PTM-0255 Unimod: Unimod:21 (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid 2-amino-3-(4-hydroxyphenyl)propanoic acid 4'-phosphate 2-azanyl-3-(4-phosphonooxyphenyl)propanoic acid MOD_RES Phosphotyrosine O4'-phospho-L-tyrosine O4'-phosphorylated L-tyrosine O4-phosphotyrosine OPTyr Phospho Tyrosinyl phosphorylationy tyrosine phosphate Phospho Phosphorylation A protein modification that effectively converts an L-histidine residue to diphthamide. DiffAvg: DiffFormula: DiffMono: FormalCharge: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2R)-1-amino-4-(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-aminium (3-[4-(2-amino-2-carboxy-ethyl)-1H-imidazol-2-yl]-1-carbamoyl-propyl)-trimethylammonium 1-azanyl-4-(4-[2-azanyl-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-azanium 2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine 2-[(R)-3-carboxamido-3-(trimethylammonio)propyl]-4-((S)-2-amino-2-carboxyethyl)-1H-imidazole 2-[3-carboxamido-3-(trimethylammonio)propyl]histidine 2-amino-3-[[2-(3-amino-3-carbamoyl-prop-1-enyl)-1,1,3-trimethyl-2,3-dihydroimidazol-5-yl]]propanoic acid 2-amino-4-[[5-(2-amino-2-carboxylato-ethyl)-1,1,3-trimethyl-2,3-dihydroimidazol-2-yl]]but-3-enamide Diphth MOD_RES Diphthamide alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-1H-imidazole-2-propanaminium diphthamide diphthamide (from histidine) PSI-MOD Diphthamide MOD:00049 2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine A protein modification that effectively converts an L-histidine residue to diphthamide. ChEBI:16692 DeltaMass:122 PubMed:15316019 PubMed:7430147 RESID:AA0040 Unimod:375#H DiffAvg: 143.21 DiffFormula: C 7 H 15 N 2 O 1 DiffMono: 143.117890 FormalCharge: 1+ Formula: C 13 H 22 N 5 O 2 MassAvg: 280.35 MassMono: 280.176801 Origin: H Source: natural TermSpec: none UniProt: PTM-0118 Unimod: Unimod:375 (2R)-1-amino-4-(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-aminium (3-[4-(2-amino-2-carboxy-ethyl)-1H-imidazol-2-yl]-1-carbamoyl-propyl)-trimethylammonium 1-azanyl-4-(4-[2-azanyl-2-carboxyethyl]-1H-imidazol-2-yl)-N,N,N-trimethyl-1-oxobutan-2-azanium 2'-[3-carboxamido-3-(trimethylammonio)propyl]-L-histidine 2-[(R)-3-carboxamido-3-(trimethylammonio)propyl]-4-((S)-2-amino-2-carboxyethyl)-1H-imidazole 2-[3-carboxamido-3-(trimethylammonio)propyl]histidine 2-amino-3-[[2-(3-amino-3-carbamoyl-prop-1-enyl)-1,1,3-trimethyl-2,3-dihydroimidazol-5-yl]]propanoic acid 2-amino-4-[[5-(2-amino-2-carboxylato-ethyl)-1,1,3-trimethyl-2,3-dihydroimidazol-2-yl]]but-3-enamide Diphth MOD_RES Diphthamide alpha-(aminocarbonyl)-4-(2-amino-2-carboxyethyl)-N,N,N-trimethyl-1H-imidazole-2-propanaminium diphthamide diphthamide (from histidine) Diphthamide Diphthamide A protein modification that effectively converts an L-alanine residue to N-acetyl-L-alanine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-(acetamido)propanoic acid 2-(acetylamino)propanoic acid 2-(acetylazanyl)propanoic acid AcAla MOD_RES N-acetylalanine N-acetyl-L-alanine N-acetylated L-alanine acetylalanine PSI-MOD MOD:00050 N-acetyl-L-alanine A protein modification that effectively converts an L-alanine residue to N-acetyl-L-alanine. PubMed:363452 PubMed:4700463 RESID:AA0041 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 5 H 8 N 1 O 2 MassAvg: 114.12 MassMono: 114.055504 Origin: A Source: natural TermSpec: N-term UniProt: PTM-0199 (2S)-2-(acetamido)propanoic acid 2-(acetylamino)propanoic acid 2-(acetylazanyl)propanoic acid AcAla MOD_RES N-acetylalanine N-acetyl-L-alanine N-acetylated L-alanine acetylalanine A protein modification that effectively converts an L-aspartic acid residue to N-acetyl-L-aspartic acid. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-(acetamido)butanedioic acid 2-(acetylamino)butanedioic acid 2-(acetylazanyl)butanedioic acid AcAsp MOD_RES N-acetylaspartate N-acetyl-L-aspartic acid N-acetylated L-aspartic acid acetylaspartic acid PSI-MOD MOD:00051 N-acetyl-L-aspartic acid A protein modification that effectively converts an L-aspartic acid residue to N-acetyl-L-aspartic acid. ChEBI:21547 PubMed:1560020 PubMed:2395459 RESID:AA0042 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 6 H 8 N 1 O 4 MassAvg: 158.13 MassMono: 158.045333 Origin: D Source: natural TermSpec: N-term UniProt: PTM-0200 (2S)-2-(acetamido)butanedioic acid 2-(acetylamino)butanedioic acid 2-(acetylazanyl)butanedioic acid AcAsp MOD_RES N-acetylaspartate N-acetyl-L-aspartic acid N-acetylated L-aspartic acid acetylaspartic acid A protein modification that effectively converts an L-cysteine residue to N-acetyl-L-cysteine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2R)-2-acetamido-3-sulfanylpropanoic acid 2-acetylamino-3-mercaptopropanoic acid 2-acetylamino-3-sulfanylpropanoic acid 2-acetylazanyl-3-sulfanylpropanoic acid MOD_RES N-acetylcysteine N-acetyl-L-cysteine N-acetylated cysteine N-acetylcysteine NAcCys PSI-MOD Acetyl MOD:00052 incidental to RESID:AA0223 N-acetyl-L-cysteine A protein modification that effectively converts an L-cysteine residue to N-acetyl-L-cysteine. ChEBI:28939 PubMed:11857757 PubMed:11999733 PubMed:12175151 PubMed:14730666 PubMed:1500421 PubMed:15350136 PubMed:6725286 RESID:AA0043 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 S 0 DiffMono: 42.010565 Formula: C 5 H 8 N 1 O 2 S 1 MassAvg: 146.18 MassMono: 146.027574 Origin: C Source: natural TermSpec: N-term UniProt: PTM-0201 (2R)-2-acetamido-3-sulfanylpropanoic acid 2-acetylamino-3-mercaptopropanoic acid 2-acetylamino-3-sulfanylpropanoic acid 2-acetylazanyl-3-sulfanylpropanoic acid MOD_RES N-acetylcysteine N-acetyl-L-cysteine N-acetylated cysteine N-acetylcysteine NAcCys Acetyl A protein modification that effectively converts an L-glutamic acid residue to N-acetyl-L-glutamic acid. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-(acetamido)pentanedioic acid 2-(acetylamino)pentanedioic acid 2-(acetylazanyl)pentanedioic acid AcGlu MOD_RES N-acetylglutamate N-acetyl-L-glutamic acid N-acetylated L-glutamic acid acetylglutamic acid PSI-MOD MOD:00053 N-acetyl-L-glutamic acid A protein modification that effectively converts an L-glutamic acid residue to N-acetyl-L-glutamic acid. ChEBI:17533 PubMed:6725286 RESID:AA0044 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 7 H 10 N 1 O 4 MassAvg: 172.16 MassMono: 172.060983 Origin: E Source: natural TermSpec: N-term UniProt: PTM-0202 (2S)-2-(acetamido)pentanedioic acid 2-(acetylamino)pentanedioic acid 2-(acetylazanyl)pentanedioic acid AcGlu MOD_RES N-acetylglutamate N-acetyl-L-glutamic acid N-acetylated L-glutamic acid acetylglutamic acid A protein modification that effectively converts an L-glutamine residue to N-acetyl-L-glutamine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-acetamido-5-pentanediamic acid 2-acetylamino-5-amino-5-oxopentanoic acid 2-acetylamino-5-pentanediamic acid 2-acetylazanyl-5-azanyl-5-oxopentanoic acid AcGln N-acetyl-L-glutamine N-acetylated L-glutamine acetylglutamine PSI-MOD MOD:00054 This is a deprecated entry in RESID. It probably does not occur naturally [JSG]. N-acetyl-L-glutamine A protein modification that effectively converts an L-glutamine residue to N-acetyl-L-glutamine. RESID:AA0045 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 7 H 11 N 2 O 3 MassAvg: 171.18 MassMono: 171.076967 Origin: Q Source: artifact TermSpec: N-term (2S)-2-acetamido-5-pentanediamic acid 2-acetylamino-5-amino-5-oxopentanoic acid 2-acetylamino-5-pentanediamic acid 2-acetylazanyl-5-azanyl-5-oxopentanoic acid AcGln N-acetyl-L-glutamine N-acetylated L-glutamine acetylglutamine A protein modification that effectively converts a glycine residue to N-acetylglycine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (acetylamino)acetic acid (acetylazanyl)ethanoic acid 2-(acetamido)ethanoic acid 2-(acetylamino)ethanoic acid AcGly MOD_RES N-acetylglycine N-acetylated glycine N-acetylglycine aceturic acid PSI-MOD MOD:00055 N-acetylglycine A protein modification that effectively converts a glycine residue to N-acetylglycine. PubMed:272676 PubMed:5545094 PubMed:6754709 RESID:AA0046 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 4 H 6 N 1 O 2 MassAvg: 100.10 MassMono: 100.039853 Origin: G Source: natural TermSpec: N-term UniProt: PTM-0203 (acetylamino)acetic acid (acetylazanyl)ethanoic acid 2-(acetamido)ethanoic acid 2-(acetylamino)ethanoic acid AcGly MOD_RES N-acetylglycine N-acetylated glycine N-acetylglycine aceturic acid A protein modification that effectively converts an L-isoleucine residue to N-acetyl-L-isoleucine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S,3S)-2-acetamido-3-methylpentanoic acid 2-acetylamino-3-methylpentanoic acid 2-acetylazanyl-3-methylpentanoic acid AcIle N-acetyl-L-isoleucine N-acetylated L-isoleucine acetylisoleucine PSI-MOD MOD:00056 This is a deprecated entry in RESID. It probably does not occur naturally [JSG]. N-acetyl-L-isoleucine A protein modification that effectively converts an L-isoleucine residue to N-acetyl-L-isoleucine. PubMed:8034631 RESID:AA0047 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 8 H 14 N 1 O 2 MassAvg: 156.20 MassMono: 156.102454 Origin: I Source: artifact TermSpec: N-term UniProt: PTM-0204 (2S,3S)-2-acetamido-3-methylpentanoic acid 2-acetylamino-3-methylpentanoic acid 2-acetylazanyl-3-methylpentanoic acid AcIle N-acetyl-L-isoleucine N-acetylated L-isoleucine acetylisoleucine A protein modification that effectively converts an L-lysine residue to N2-acetyl-L-lysine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: (2S)-2-acetamido-6-aminohexanoic acid 2-acetylamino-6-aminohexanoic acid 2-acetylazanyl-6-azanylhexanoic acid N2-acetyl-L-lysine N2-acetylated L-lysine N2-acetyllysine N2AcLys PSI-MOD Acetyl MOD:00057 This is a deprecated entry in RESID. It probably does not occur naturally [JSG]. N2-acetyl-L-lysine A protein modification that effectively converts an L-lysine residue to N2-acetyl-L-lysine. PubMed:11857757 PubMed:11999733 PubMed:12175151 PubMed:14730666 PubMed:15350136 RESID:AA0048 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 8 H 15 N 2 O 2 MassAvg: 171.22 MassMono: 171.113353 Origin: K Source: artifact TermSpec: N-term (2S)-2-acetamido-6-aminohexanoic acid 2-acetylamino-6-aminohexanoic acid 2-acetylazanyl-6-azanylhexanoic acid N2-acetyl-L-lysine N2-acetylated L-lysine N2-acetyllysine N2AcLys Acetyl A protein modification that effectively converts an L-methionine to N-acetyl-L-methionine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid 2-acetylamino-4-(methylsulfanyl)butanoic acid 2-acetylamino-4-(methylthio)butanoic acid 2-acetylazanyl-4-(methylsulfanyl)butanoic acid AcMet MOD_RES N-acetylmethionine N-acetyl-L-methionine N-acetylated L-methionine acetylmethionine methionamine PSI-MOD MOD:00058 N-acetyl-L-methionine AcMet MOD_RES N-acetylmethionine N-acetyl-L-methionine N-acetylated L-methionine acetylmethionine methionamine A protein modification that effectively converts an L-methionine to N-acetyl-L-methionine. PubMed:7944406 RESID:AA0049 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 S 0 DiffMono: 42.010565 Formula: C 7 H 12 N 1 O 2 S 1 MassAvg: 174.24 MassMono: 174.058875 Origin: M Source: natural TermSpec: N-term UniProt: PTM-0205 (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid 2-acetylamino-4-(methylsulfanyl)butanoic acid 2-acetylamino-4-(methylthio)butanoic acid 2-acetylazanyl-4-(methylsulfanyl)butanoic acid A protein modification that effectively converts an L-proline residue to N-acetyl-L-proline. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-1-acetyl-2-pyrrolidinecarboxylic acid 1-acetylproline MOD_RES N-acetylproline N-acetyl-L-proline N-acetylated L-proline N-acetylproline NAcPro acetylproline PSI-MOD MOD:00059 N-acetyl-L-proline A protein modification that effectively converts an L-proline residue to N-acetyl-L-proline. PubMed:2928307 RESID:AA0050 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 7 H 10 N 1 O 2 MassAvg: 140.16 MassMono: 140.071154 Origin: P Source: natural TermSpec: N-term UniProt: PTM-0206 (2S)-1-acetyl-2-pyrrolidinecarboxylic acid 1-acetylproline MOD_RES N-acetylproline N-acetyl-L-proline N-acetylated L-proline N-acetylproline NAcPro acetylproline A protein modification that effectively converts an L-serine residue to N-acetyl-L-serine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-acetamido-3-hydroxypropanoic acid 2-acetylamino-3-hydroxypropanoic acid 2-acetylazanyl-3-hydroxypropanoic acid MOD_RES N-acetylserine N-acetyl-L-serine N-acetylated L-serine N-acetylserine NAcSer PSI-MOD Acetyl MOD:00060 N-acetyl-L-serine A protein modification that effectively converts an L-serine residue to N-acetyl-L-serine. PubMed:11857757 PubMed:11999733 PubMed:12175151 PubMed:14730666 PubMed:15350136 PubMed:1880797 PubMed:2106685 PubMed:6997045 RESID:AA0051 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 5 H 8 N 1 O 3 MassAvg: 130.12 MassMono: 130.050418 Origin: S Source: natural TermSpec: N-term UniProt: PTM-0207 (2S)-2-acetamido-3-hydroxypropanoic acid 2-acetylamino-3-hydroxypropanoic acid 2-acetylazanyl-3-hydroxypropanoic acid MOD_RES N-acetylserine N-acetyl-L-serine N-acetylated L-serine N-acetylserine NAcSer Acetyl A protein modification that effectively converts an L-threonine residue to N-acetyl-L-threonine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S,3R)-2-acetamido-3-hydroxybutanoic acid 2-acetylamino-3-hydroxybutanoic acid 2-acetylazanyl-3-hydroxybutanoic acid MOD_RES N-acetylthreonine N-acetyl-L-threonine N-acetylated L-threonine N-acetylthreonine N-methylcarbonylthreonine NAcThr PSI-MOD Acetyl Acetylation MOD:00061 N-acetyl-L-threonine A protein modification that effectively converts an L-threonine residue to N-acetyl-L-threonine. PubMed:11857757 PubMed:11999733 PubMed:12175151 PubMed:14730666 PubMed:15350136 PubMed:2106685 PubMed:6997045 RESID:AA0052 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 6 H 10 N 1 O 3 MassAvg: 144.15 MassMono: 144.066068 Origin: T Source: natural TermSpec: N-term UniProt: PTM-0208 (2S,3R)-2-acetamido-3-hydroxybutanoic acid 2-acetylamino-3-hydroxybutanoic acid 2-acetylazanyl-3-hydroxybutanoic acid MOD_RES N-acetylthreonine N-acetyl-L-threonine N-acetylated L-threonine N-acetylthreonine N-methylcarbonylthreonine NAcThr Acetyl Acetylation A protein modification that effectively converts an L-tyrosine residue to N-acetyl-L-tyrosine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-acetamido-3-(4-hydoxyphenyl)propanoic acid 2-acetylamino-3-(4-hydoxyphenyl)propanoic acid 2-acetylazanyl-3-(4-hydoxyphenyl)propanoic acid AcTyr MOD_RES N-acetyltyrosine N-acetyl-L-tyrosine N-acetylated L-tyrosine N-acetyltyrosine PSI-MOD Acetyl MOD:00062 N-acetyl-L-tyrosine A protein modification that effectively converts an L-tyrosine residue to N-acetyl-L-tyrosine. PubMed:11857757 PubMed:11999733 PubMed:12175151 PubMed:14730666 PubMed:15350136 PubMed:2506074 PubMed:475783 RESID:AA0053 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 11 H 12 N 1 O 3 MassAvg: 206.22 MassMono: 206.081718 Origin: Y Source: natural TermSpec: N-term UniProt: PTM-0209 (2S)-2-acetamido-3-(4-hydoxyphenyl)propanoic acid 2-acetylamino-3-(4-hydoxyphenyl)propanoic acid 2-acetylazanyl-3-(4-hydoxyphenyl)propanoic acid AcTyr MOD_RES N-acetyltyrosine N-acetyl-L-tyrosine N-acetylated L-tyrosine N-acetyltyrosine Acetyl A protein modification that effectively converts an L-valine residue to N-acetyl-L-valine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-acetamido-3-methylbutanoic acid 2-acetylamino-3-methylbutanoic acid 2-acetylazanyl-3-methylbutanoic acid AcVal MOD_RES N-acetylvaline N-acetyl-L-valine N-acetylated L-valine N-acetylvaline PSI-MOD MOD:00063 N-acetyl-L-valine A protein modification that effectively converts an L-valine residue to N-acetyl-L-valine. PubMed:1735421 RESID:AA0054 DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 7 H 12 N 1 O 2 MassAvg: 142.18 MassMono: 142.086804 Origin: V Source: natural TermSpec: N-term UniProt: PTM-0210 (2S)-2-acetamido-3-methylbutanoic acid 2-acetylamino-3-methylbutanoic acid 2-acetylazanyl-3-methylbutanoic acid AcVal MOD_RES N-acetylvaline N-acetyl-L-valine N-acetylated L-valine N-acetylvaline A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-6-acetamido-2-aminohexanoic acid 6-acetylamino-2-aminohexanoic acid 6-acetylazanyl-2-aminohexanoic acid MOD_RES N6-acetyllysine N(zeta)-acetyllysine N6-acetyl-L-lysine N6-acetylated L-lysine N6AcLys acetylk epsilon-acetyllysine PSI-MOD Acetyl Acetylation MOD:00064 N6-acetyl-L-lysine A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine. ChEBI:17752 DeltaMass:214 OMSSA:24 PubMed:11369851 PubMed:11857757 PubMed:11999733 PubMed:12175151 PubMed:14730666 PubMed:15350136 PubMed:1680872 PubMed:670159 RESID:AA0055 Unimod:1#K DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 DiffMono: 42.010565 Formula: C 8 H 14 N 2 O 2 MassAvg: 170.21 MassMono: 170.105528 Origin: K Source: natural TermSpec: none UniProt: PTM-0190 Unimod: Unimod:1 (2S)-6-acetamido-2-aminohexanoic acid 6-acetylamino-2-aminohexanoic acid 6-acetylazanyl-2-aminohexanoic acid MOD_RES N6-acetyllysine N(zeta)-acetyllysine N6-acetyl-L-lysine N6-acetylated L-lysine N6AcLys acetylk epsilon-acetyllysine Acetyl Acetylation A protein modification that effectively converts an L-cysteine residue to S-acetyl-L-cysteine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: Unimod: (2R)-3-acetylsulfanyl-2-aminopropanoic acid 2-amino-3-(acetylthio)propanoic acid 2-azanyl-3-(acetylsulfanyl)propanoic acid ACT_SITE S-acetylcysteine intermediate S-acetyl-L-cysteine S-acetylcysteine SAcCys cysteine acetate thioester PSI-MOD Acetyl Acetylation MOD:00065 S-acetyl-L-cysteine A protein modification that effectively converts an L-cysteine residue to S-acetyl-L-cysteine. PubMed:11857757 PubMed:11999733 PubMed:12175151 PubMed:1310545 PubMed:14730666 PubMed:15350136 RESID:AA0056 Unimod:1#C DiffAvg: 42.04 DiffFormula: C 2 H 2 N 0 O 1 S 0 DiffMono: 42.010565 Formula: C 5 H 7 N 1 O 2 S 1 MassAvg: 145.18 MassMono: 145.019749 Origin: C Source: natural TermSpec: none Unimod: Unimod:1 (2R)-3-acetylsulfanyl-2-aminopropanoic acid 2-amino-3-(acetylthio)propanoic acid 2-azanyl-3-(acetylsulfanyl)propanoic acid ACT_SITE S-acetylcysteine intermediate S-acetyl-L-cysteine S-acetylcysteine SAcCys cysteine acetate thioester Acetyl Acetylation A protein modification that effectively converts a glycine residue to N-formylglycine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (formylamino)acetic acid (formylamino)ethanoic acid (formylazanyl)ethanoic acid 2-formamidoacetic acid 2-formamidoethanoic acid MOD_RES N-formylglycine N(alpha)-formylglycine N-formylated glycine N-formylglycine NFoGly PSI-MOD MOD:00066 N-formylglycine A protein modification that effectively converts a glycine residue to N-formylglycine. PubMed:5139483 RESID:AA0057 DiffAvg: 28.01 DiffFormula: C 1 H 0 N 0 O 1 DiffMono: 27.994915 Formula: C 3 H 4 N 1 O 2 MassAvg: 86.07 MassMono: 86.024203 Origin: G Source: natural TermSpec: N-term UniProt: PTM-0211 (formylamino)acetic acid (formylamino)ethanoic acid (formylazanyl)ethanoic acid 2-formamidoacetic acid 2-formamidoethanoic acid MOD_RES N-formylglycine N(alpha)-formylglycine N-formylated glycine N-formylglycine NFoGly A protein modification that effectively converts a glycine residue to N-D-glucuronoylglycine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: 2-(glucuronoylamino)ethanoic acid MOD_RES N-D-glucuronoyl glycine N-D-glucuronoyl-glycine N-D-glucuronyl-glycine NGlcAGly ntermpepglucuronylg PSI-MOD Glucuronyl MOD:00067 N-D-glucuronoylglycine A protein modification that effectively converts a glycine residue to N-D-glucuronoylglycine. OMSSA:50 PubMed:10858503 PubMed:12716131 PubMed:6493057 PubMed:7398618 RESID:AA0058 DiffAvg: 176.12 DiffFormula: C 6 H 8 N 0 O 6 DiffMono: 176.032088 Formula: C 8 H 12 N 1 O 7 MassAvg: 234.18 MassMono: 234.061377 Origin: G Source: natural TermSpec: N-term UniProt: PTM-0331 2-(glucuronoylamino)ethanoic acid MOD_RES N-D-glucuronoyl glycine N-D-glucuronoyl-glycine N-D-glucuronyl-glycine NGlcAGly ntermpepglucuronylg Glucuronyl A protein modification that effectively converts a glycine residue to N-myristoylglycine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (tetradecanoylamino)ethanoic acid LIPID N-myristoyl glycine N-(1-oxotetradecyl)glycine N-(C14:0 aliphatic acyl)glycine N-myristoyl-glycine N-myristoylated glycine N-myristylglycine N-tetradecanoylglycine NMyrGly ntermpepmyristoylationg PSI-MOD Myristoyl Myristoylation MOD:00068 N-myristoylglycine A protein modification that effectively converts a glycine residue to N-myristoylglycine. OMSSA:80 PubMed:11955007 PubMed:11955008 PubMed:1326520 PubMed:1386601 PubMed:6436247 PubMed:7543369 RESID:AA0059 Unimod:45#G DiffAvg: 210.36 DiffFormula: C 14 H 26 N 0 O 1 DiffMono: 210.198365 Formula: C 16 H 30 N 1 O 2 MassAvg: 268.42 MassMono: 268.227654 Origin: G Source: natural TermSpec: N-term UniProt: PTM-0221 Unimod: Unimod:45 (tetradecanoylamino)ethanoic acid LIPID N-myristoyl glycine N-(1-oxotetradecyl)glycine N-(C14:0 aliphatic acyl)glycine N-myristoyl-glycine N-myristoylated glycine N-myristylglycine N-tetradecanoylglycine NMyrGly ntermpepmyristoylationg Myristoyl Myristoylation A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2R)-2-hexadecanoylamino-3-sulfanylpropanoic acid 2-hexadecanamido-3-sulfanylpropanoic acid 2-hexadecanoylamino-3-mercaptopropanoic acid LIPID N-palmitoyl cysteine N-(1-oxahexadecyl)-L-cysteine N-hexadecanoylated L-cysteine N-palmitoyl-L-cysteine N-palmitoylated L-cysteine NPamCys PSI-MOD Palmitoyl Palmitoylation MOD:00069 incidental to RESID:AA0107 incidental to RESID:AA0309 N-palmitoyl-L-cysteine A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine. PubMed:10896212 PubMed:4575979 PubMed:9056182 PubMed:9593755 RESID:AA0060 DiffAvg: 238.41 DiffFormula: C 16 H 30 N 0 O 1 S 0 DiffMono: 238.229666 Formula: C 19 H 36 N 1 O 2 S 1 MassAvg: 342.56 MassMono: 342.246675 Origin: C Source: natural TermSpec: N-term UniProt: PTM-0222 (2R)-2-hexadecanoylamino-3-sulfanylpropanoic acid 2-hexadecanamido-3-sulfanylpropanoic acid 2-hexadecanoylamino-3-mercaptopropanoic acid LIPID N-palmitoyl cysteine N-(1-oxahexadecyl)-L-cysteine N-hexadecanoylated L-cysteine N-palmitoyl-L-cysteine N-palmitoylated L-cysteine NPamCys Palmitoyl Palmitoylation A protein modification that effectively converts an L-alanine residue to N-methyl-L-alanine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-methylaminopropanoic acid 2-methylazanylpropanoic acid MOD_RES N-methylalanine N-methyl-L-alanine N-methylalanine N-methylated L-alanine NMe1Ala PSI-MOD Methyl Methylation MOD:00070 Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG]. N-methyl-L-alanine A protein modification that effectively converts an L-alanine residue to N-methyl-L-alanine. ChEBI:17519 PubMed:323502 PubMed:337304 PubMed:7007074 RESID:AA0061 DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 4 H 7 N 1 O 1 MassAvg: 85.11 MassMono: 85.052764 Origin: A Source: natural TermSpec: N-term UniProt: PTM-0214 (2S)-2-methylaminopropanoic acid 2-methylazanylpropanoic acid MOD_RES N-methylalanine N-methyl-L-alanine N-methylalanine N-methylated L-alanine NMe1Ala Methyl Methylation A protein modification that effectively converts an L-alanine residue to N,N,N-trimethyl-L-alanine. DiffAvg: DiffFormula: DiffMono: FormalCharge: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (1S)-1-carboxy-N,N,N-trimethylethanaminium (1S)-1-carboxy-N,N,N-trimethylethanazanium (2S)-2-(trimethylammonio)propanoic acid MOD_RES N,N,N-trimethylalanine N,N,N-trimethyl-L-alanine N,N,N-trimethylalanine cation N,N,N-trimethylalaninium N,N,N-trimethylated L-alanine N2Me3+Ala NMe3Ala PSI-MOD Trimethyl tri-Methylation MOD:00071 N,N,N-trimethyl-L-alanine A protein modification that effectively converts an L-alanine residue to N,N,N-trimethyl-L-alanine. PubMed:12590383 PubMed:332162 PubMed:3979397 PubMed:6778808 PubMed:7715456 RESID:AA0062 DiffAvg: 43.09 DiffFormula: C 3 H 7 N 0 O 0 DiffMono: 43.054227 FormalCharge: 1+ Formula: C 6 H 13 N 1 O 1 MassAvg: 115.18 MassMono: 115.099165 Origin: A Source: natural TermSpec: N-term UniProt: PTM-0177 (1S)-1-carboxy-N,N,N-trimethylethanaminium (1S)-1-carboxy-N,N,N-trimethylethanazanium (2S)-2-(trimethylammonio)propanoic acid MOD_RES N,N,N-trimethylalanine N,N,N-trimethyl-L-alanine N,N,N-trimethylalanine cation N,N,N-trimethylalaninium N,N,N-trimethylated L-alanine N2Me3+Ala NMe3Ala Trimethyl tri-Methylation A protein modification that effectively converts a glycine residue to N-methylglycine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: L-sarcosine MOD_RES N-methylglycine N-methylated glycine N-methylglycine NMe1Gly Sar Sarcosine Sarcosyl methylaminoacetic acid methylaminoethanoic acid PSI-MOD Methyl Methylation MOD:00072 DeltaMass also has an entry for the free amino acid. Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG]. N-methylglycine A protein modification that effectively converts a glycine residue to N-methylglycine. ChEBI:15611 DeltaMass:0 PubMed:1593629 RESID:AA0063 DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 3 H 5 N 1 O 1 MassAvg: 71.08 MassMono: 71.037114 Origin: G Source: natural TermSpec: N-term UniProt: PTM-0483 L-sarcosine MOD_RES N-methylglycine N-methylated glycine N-methylglycine NMe1Gly Sar Sarcosine Sarcosyl methylaminoacetic acid methylaminoethanoic acid Methyl Methylation A protein modification that effectively converts an L-methionine residue to N-methyl-L-methionine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-methylamino-4-(methylsulfanyl)butanoic acid 2-methylamino-4-(methylthio)butanoic acid MOD_RES N-methylmethionine Methyl Methionyl N-methyl-L-methionine N-methylated L-methionine N-methylmethionine NMe1Met PSI-MOD Methyl Methylation MOD:00073 Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG]. N-methyl-L-methionine A protein modification that effectively converts an L-methionine residue to N-methyl-L-methionine. DeltaMass:169 PubMed:323502 PubMed:3298225 RESID:AA0064 DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 S 0 DiffMono: 14.015650 Formula: C 6 H 11 N 1 O 1 S 1 MassAvg: 145.22 MassMono: 145.056135 Origin: M Source: natural TermSpec: N-term UniProt: PTM-0217 (2S)-2-methylamino-4-(methylsulfanyl)butanoic acid 2-methylamino-4-(methylthio)butanoic acid MOD_RES N-methylmethionine Methyl Methionyl N-methyl-L-methionine N-methylated L-methionine N-methylmethionine NMe1Met Methyl Methylation A protein modification that effectively converts an L-phenylalanine residue to N-methyl-L-phenylalanine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-methylamino-3-phenylpropanoic acid MOD_RES N-methylphenylalanine N-methyl-L-phenylalanine N-methylated L-phenylalanine N-methylphenylalanine NMe1Phe PSI-MOD Methyl Methylation MOD:00074 Polypeptides with monomethylated amino terminals can undergo premature cleavage during the coupling step of an Edman degradation. This can result in "preview" with both a residue and the following residue being seen from the first step on through a sequence [JSG]. N-methyl-L-phenylalanine A protein modification that effectively converts an L-phenylalanine residue to N-methyl-L-phenylalanine. PubMed:2577730 PubMed:413571 RESID:AA0065 DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 10 H 11 N 1 O 1 MassAvg: 161.20 MassMono: 161.084064 Origin: F Source: natural TermSpec: N-term UniProt: PTM-0218 (2S)-2-methylamino-3-phenylpropanoic acid MOD_RES N-methylphenylalanine N-methyl-L-phenylalanine N-methylated L-phenylalanine N-methylphenylalanine NMe1Phe Methyl Methylation A protein modification that effectively converts an L-proline residue to N,N-dimethyl-L-proline. DiffAvg: DiffFormula: DiffMono: FormalCharge: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-carboxy-1,1-dimethylpyrrolidinium 1,1-dimethyl-L-prolinium MOD_RES N,N-dimethylproline N,N-dimethyl-L-proline N,N-dimethyl-L-prolinium N,N-dimethylated L-proline NMe2Pro stachydrin PSI-MOD Delta:H(5)C(2) Dimethyl Dimethylation of proline residue MOD:00075 Unimod terminal specification corrected [JSG]. N,N-dimethyl-L-proline A protein modification that effectively converts an L-proline residue to N,N-dimethyl-L-proline. ChEBI:21451 PubMed:12964758 PubMed:14570711 PubMed:193025 PubMed:3882426 PubMed:6254758 RESID:AA0066 Unimod:529 DiffAvg: 29.06 DiffFormula: C 2 H 5 N 0 O 0 DiffMono: 29.038577 FormalCharge: 1+ Formula: C 7 H 13 N 1 O 1 MassAvg: 127.19 MassMono: 127.099165 Origin: P Source: natural TermSpec: N-term UniProt: PTM-0179 Unimod: Unimod:529 (2S)-2-carboxy-1,1-dimethylpyrrolidinium 1,1-dimethyl-L-prolinium MOD_RES N,N-dimethylproline N,N-dimethyl-L-proline N,N-dimethyl-L-prolinium N,N-dimethylated L-proline NMe2Pro stachydrin Delta:H(5)C(2) Dimethyl Dimethylation of proline residue A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-5-[((methylamino)(methylimino)methyl)amino]pentanoic acid MOD_RES Omega-N-methylated arginine MOD_RES Symmetric dimethylarginine N3,N4-dimethylarginine N5-[(methylamino)(methylimino)methyl]ornithine NG,N'G-dimethylarginine NoNo'Me2Arg omega-N,omega-N'-dimethyl-L-arginine omega-N,omega-N'-dimethylated L-arginine symmetric dimethylarginine PSI-MOD Dimethyl di-Methylation MOD:00076 symmetric dimethyl-L-arginine A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine. PubMed:12964758 PubMed:14570711 PubMed:15835918 PubMed:2426402 PubMed:5128665 RESID:AA0067 Unimod:36#R DiffAvg: 28.05 DiffFormula: C 2 H 4 N 0 O 0 DiffMono: 28.031300 Formula: C 8 H 16 N 4 O 1 MassAvg: 184.24 MassMono: 184.132411 Origin: R Source: natural TermSpec: none UniProt: PTM-0287 Unimod: Unimod:36 (2S)-2-amino-5-[((methylamino)(methylimino)methyl)amino]pentanoic acid MOD_RES Omega-N-methylated arginine MOD_RES Symmetric dimethylarginine N3,N4-dimethylarginine N5-[(methylamino)(methylimino)methyl]ornithine NG,N'G-dimethylarginine NoNo'Me2Arg omega-N,omega-N'-dimethyl-L-arginine omega-N,omega-N'-dimethylated L-arginine symmetric dimethylarginine Dimethyl di-Methylation A protein modification that effectively converts an L-arginine residue to asymmetric dimethylarginine, N(omega),N(omega)-dimethyl-L-arginine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-5-([(dimethylamino)(imino)methyl]amino)pentanoic acid MOD_RES Asymmetric dimethylarginine MOD_RES Omega-N-methylated arginine N5-[(dimethylamino)(imino)methyl]ornithine NG,NG-dimethylarginine NoNoMe2Arg asymmetric dimethylarginine omega-N,omega-N-dimethlyated L-arginine omega-N,omega-N-dimethyl-L-arginine PSI-MOD Dimethyl di-Methylation MOD:00077 asymmetric dimethyl-L-arginine A protein modification that effectively converts an L-arginine residue to asymmetric dimethylarginine, N(omega),N(omega)-dimethyl-L-arginine. ChEBI:17929 PubMed:11152131 PubMed:12964758 PubMed:14570711 PubMed:15835918 PubMed:3032834 RESID:AA0068 Unimod:36#R DiffAvg: 28.05 DiffFormula: C 2 H 4 N 0 O 0 DiffMono: 28.031300 Formula: C 8 H 16 N 4 O 1 MassAvg: 184.24 MassMono: 184.132411 Origin: R Source: natural TermSpec: none UniProt: PTM-0066 Unimod: Unimod:36 (2S)-2-amino-5-([(dimethylamino)(imino)methyl]amino)pentanoic acid MOD_RES Asymmetric dimethylarginine MOD_RES Omega-N-methylated arginine N5-[(dimethylamino)(imino)methyl]ornithine NG,NG-dimethylarginine NoNoMe2Arg asymmetric dimethylarginine omega-N,omega-N-dimethlyated L-arginine omega-N,omega-N-dimethyl-L-arginine Dimethyl di-Methylation A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-amino-5-[(imino(methylamino)methyl)amino]pentanoic acid MOD_RES Omega-N-methylarginine MOD_RES Omega-N-methylated arginine NG-methylarginine NoMeArg omega-N-methyl-L-arginine omega-N-methylated L-arginine PSI-MOD Methyl Methylation MOD:00078 omega-N-methyl-L-arginine A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine. PubMed:11875433 PubMed:15835918 PubMed:2426402 PubMed:5128665 RESID:AA0069 DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 7 H 14 N 4 O 1 MassAvg: 170.22 MassMono: 170.116761 Origin: R Source: natural TermSpec: none UniProt: PTM-0237 (2S)-2-amino-5-[(imino(methylamino)methyl)amino]pentanoic acid MOD_RES Omega-N-methylarginine MOD_RES Omega-N-methylated arginine NG-methylarginine NoMeArg omega-N-methyl-L-arginine omega-N-methylated L-arginine Methyl Methylation A protein modification that effectively converts an L-asparagine residue to N4-methyl-L-asparagine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-N4-methylbutanediamic acid MOD_RES N4-methylasparagine N(gamma)-methylasparagine N-methylasparagine N4-methyl-L-asparagine N4-methylated L-asparagine N4Me1Asn beta-aspartyl methylamide methyln PSI-MOD Methyl Methylation beta-methylasparagine MOD:00079 N4-methyl-L-asparagine A protein modification that effectively converts an L-asparagine residue to N4-methyl-L-asparagine. OMSSA:75 PubMed:11875433 PubMed:2356973 PubMed:3782095 RESID:AA0070 Unimod:34#N DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 5 H 8 N 2 O 2 MassAvg: 128.13 MassMono: 128.058578 Origin: N Source: natural TermSpec: none UniProt: PTM-0183 Unimod: Unimod:34 (2S)-2-amino-N4-methylbutanediamic acid MOD_RES N4-methylasparagine N(gamma)-methylasparagine N-methylasparagine N4-methyl-L-asparagine N4-methylated L-asparagine N4Me1Asn beta-aspartyl methylamide methyln Methyl Methylation beta-methylasparagine A protein modification that effectively converts an L-glutamine residue to N5-methyl-L-glutamine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-amino-5-methylamino-5-oxopentanoic acid 2-amino-N5-methylpentanediamic acid MOD_RES N5-methylglutamine N(delta)-methylglutamine N-methylglutamine N5-methyl-L-glutamine N5-methylated L-glutamine N5Me1Gln gamma-methylglutamine PSI-MOD Methyl Methylation MOD:00080 N5-methyl-L-glutamine A protein modification that effectively converts an L-glutamine residue to N5-methyl-L-glutamine. ChEBI:17592 DeltaMass:166 PubMed:11118225 PubMed:11875433 PubMed:365579 RESID:AA0071 DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 6 H 10 N 2 O 2 MassAvg: 142.16 MassMono: 142.074228 Origin: Q Source: natural TermSpec: none UniProt: PTM-0185 (2S)-2-amino-5-methylamino-5-oxopentanoic acid 2-amino-N5-methylpentanediamic acid MOD_RES N5-methylglutamine N(delta)-methylglutamine N-methylglutamine N5-methyl-L-glutamine N5-methylated L-glutamine N5Me1Gln gamma-methylglutamine Methyl Methylation A protein modification that effectively converts an L-glutamic acid residue to L-glutamate 5-methyl ester. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-5-methoxy-5-oxopentanoic acid (5)-methyl L-hydrogen glutamate 2-aminopentanedioic acid 5-methyl ester 5-methyl L-2-aminoglutarate 5-methyl L-glutamate 5-methyl esterified L-glutamic acid L-glutamic acid 5-methyl ester MOD_RES Glutamate methyl ester (Glu) O-methyl Glutamyl O5MeGlu glutamic acid 5-methyl ester glutamic acid gamma-methyl ester meestere methyle PSI-MOD Methyl Methylation methyl ester MOD:00081 DeltaMass gives the formula "C 6 H 9 O 1 N 3" with mass 143 (formula incorrect, N and O reversed) [JSG]. L-glutamic acid 5-methyl ester (Glu) A protein modification that effectively converts an L-glutamic acid residue to L-glutamate 5-methyl ester. DeltaMass:167 OMSSA:17 OMSSA:70 PubMed:16888 PubMed:6300110 RESID:AA0072#GLU Unimod:34#E DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 6 H 9 N 1 O 3 MassAvg: 143.14 MassMono: 143.058243 Origin: E Source: natural TermSpec: none UniProt: PTM-0128 Unimod: Unimod:34 (2S)-2-amino-5-methoxy-5-oxopentanoic acid (5)-methyl L-hydrogen glutamate 2-aminopentanedioic acid 5-methyl ester 5-methyl L-2-aminoglutarate 5-methyl L-glutamate 5-methyl esterified L-glutamic acid L-glutamic acid 5-methyl ester MOD_RES Glutamate methyl ester (Glu) O-methyl Glutamyl O5MeGlu glutamic acid 5-methyl ester glutamic acid gamma-methyl ester meestere methyle Methyl Methylation methyl ester A protein modification that effectively converts an L-histidine residue to pros-methyl-L-histidine (N-pi-methyl-L-histidine, 3'-methyl-L-histidine). DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (2S)-2-amino-3-(3-methyl-3H-imidazol-4-yl)propanoic acid 3'-methyl-L-histidine MOD_RES Pros-methylhistidine N(delta)-methylhistidine N(pi)-methylhistidine NpMeHis pros-methylated L-histidine pros-methylhistidine PSI-MOD 1-methylhistidine Methyl Methylation MOD:00082 3'-methyl-L-histidine A protein modification that effectively converts an L-histidine residue to pros-methyl-L-histidine (N-pi-methyl-L-histidine, 3'-methyl-L-histidine). PubMed:10660523 PubMed:11875433 PubMed:3467365 PubMed:6692818 PubMed:8076 PubMed:8645219 RESID:AA0073 DiffAvg: 14.03 DiffFormula: C 1 H 2 N 0 O 0 DiffMono: 14.015650 Formula: C 7 H 9 N 3 O 1 MassAvg: 151.17 MassMono: 151.074562 Origin: H Source: natural TermSpec: none UniProt: PTM-0259 (2S)-2-amino-3-(3-methyl-3H-imidazol-4-yl)propanoic acid 3'-methyl-L-histidine MOD_RES Pros-methylhistidine N(delta)-methylhistidine N(pi)-methylhistidine NpMeHis pros-methylated L-histidine pros-methylhistidine 1-methylhistidine Methyl Methylation A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine. DiffAvg: DiffFormula: DiffMono: FormalCharge: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N-trimethylation (of lysine) N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation N6Me3+Lys epsilon-trimethyllysine PSI-MOD Trimethyl tri-Methylation MOD:00083 DeltaMass calculates the mass difference from protonated lysine rather than neutral lysine; for trimethylated lysine starting from protonated lysine see MOD:00855 N6,N6,N6-trimethyl-L-lysine A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine. ChEBI:17311 PubMed:12590383 PubMed:3145979 PubMed:4304194 PubMed:6778808 PubMed:7093227 PubMed:8453381 RESID:AA0074 DiffAvg: 43.09 DiffFormula: C 3 H 7 N 0 O 0 DiffMono: 43.054227 FormalCharge: 1+ Formula: C 9 H 19 N 2 O 1 MassAvg: 171.26 MassMono: 171.149190 Origin: K Source: natural TermSpec: none UniProt: PTM-0187 (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N-trimethylation (of lysine) N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation N6Me3+Lys epsilon-trimethyllysine Trimethyl tri-Methylation A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine. DiffAvg: DiffFormula: DiffMono: Formula: MassAvg: MassMono: Origin: Source: TermSpec: UniProt: Unimod: (2S)-2-amino-6-(dimethylamino)hexanoic acid MOD_RES N6,N6-dimethyllysine N(zeta)-dimethyllysine N6,N6-dimethyl-L-lysine N6,N6-dimethylated L-lysine N6Me2Lys dimethylk epsilon-dimethyllysine lysine derivative Lys(y) PSI-MOD Dimethyl di-Methylation MOD:00084 N6,N6-dimethyl-L-lysine A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine. OMSSA:36 PubMed:10550045 PubMed:12964758 PubMed:14570711 PubMed:3100523 PubMed:8453381 RESID:AA0075 Unimod:36#K DiffAvg: 28.05 DiffFormula: C 2 H 4 N 0 O 0 DiffMono: 28.031300 Formula: C 8 H 16 N 2 O 1 MassAvg: 156.23 MassMono: 156.126263 Origin: K Source: natural TermSpec: none UniProt: PTM-0188 Unimod: Unimod:36 (2S)-2-amino-6-(dimethylamino)hexanoic acid