xlmod.owl
type: Ontology
version IRI: xlmod.owl
auto-generated-by: OBO-Edit 2.3.1
date: 11:07:2025 17:25
default-namespace: XLMOD
has_obo_format_version: 1.2
saved-by: Douwe Schulte
comment: This work is licensed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.
comment: To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/ or send a letter to Creative Commons, 444 Castro Street, Suite 900, Mountain View, California, 94041, USA.
comment: coverage: cross-linking reagents, cross-linker related post-translational modifications, and derivatization reagents for GC-MS and LC-MS
comment: creator: Alexander Leitner <leitner <-at-> imsb.biol.ethz.ch>
comment: creator: Gerhard Mayer <mayerg97 <-at-> rub.de>
comment: creator: Lutz Fischer <lfischer <-at-> staffmail.ed.ac.uk>
comment: creator: Nils Hoffmann <nils.hoffmann <-at-> isas.de>
comment: version: 1.1.12

definition
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_obo_format_version
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

has_chromophore
type: ObjectProperty
definition: Indicates that the derivatization reagent can be detected by the specified chromophore.
has_obo_namespace: XLMOD
id: has_chromophore

Axiom
annotated source: has_chromophore
annotated property: definition
annotated target: Indicates that the derivatization reagent can be detected by the specified chromophore.
database_cross_reference: OBO:defs

has_click_enabled_linker
type: ObjectProperty
definition: Indicates that the cross-linking reagent has a linker that can be enabled by click chemistry.
has_obo_namespace: XLMOD
id: has_click_enabled_linker

Axiom
annotated source: has_click_enabled_linker
annotated property: definition
annotated target: Indicates that the cross-linking reagent has a linker that can be enabled by click chemistry.
database_cross_reference: OBO:defs

has_electrophore
type: ObjectProperty
definition: Indicates that the derivatization reagent can be detected by the specified electrophore.
has_obo_namespace: XLMOD
id: has_electrophore

Axiom
annotated source: has_electrophore
annotated property: definition
annotated target: Indicates that the derivatization reagent can be detected by the specified electrophore.
database_cross_reference: OBO:defs

has_fluorophore
type: ObjectProperty
definition: Indicates that the derivatization reagent can be detected by the specified fluorophore.
has_obo_namespace: XLMOD
id: has_fluorophore

Axiom
annotated source: has_fluorophore
annotated property: definition
annotated target: Indicates that the derivatization reagent can be detected by the specified fluorophore.
database_cross_reference: OBO:defs

has_handle
type: ObjectProperty
definition: Indicates that the cross-linking reagent has a handle that can be used for detection/identification, enrichment or purification.
has_obo_namespace: XLMOD
id: has_handle

Axiom
annotated source: has_handle
annotated property: definition
annotated target: Indicates that the cross-linking reagent has a handle that can be used for detection/identification, enrichment or purification.
database_cross_reference: OBO:defs

has_neutral_loss_reporter
type: ObjectProperty
definition: Indicates that the cross-linking reagent has a neutral loss reporter.
has_obo_namespace: XLMOD
id: has_neutral_loss_reporter

Axiom
annotated source: has_neutral_loss_reporter
annotated property: definition
annotated target: Indicates that the cross-linking reagent has a neutral loss reporter.
database_cross_reference: OBO:defs

has_property
type: ObjectProperty
definition: Indicates a property of a cross-linking or derivatization reagent.
has_obo_namespace: XLMOD
id: has_property

Axiom
annotated source: has_property
annotated property: definition
annotated target: Indicates a property of a cross-linking or derivatization reagent.
database_cross_reference: OBO:defs

has_reactive_group
type: ObjectProperty
definition: Indicates that the cross-linking or derivatization reagent has the specified reactive group.
has_obo_namespace: XLMOD
id: has_reactive_group

Axiom
annotated source: has_reactive_group
annotated property: definition
annotated target: Indicates that the cross-linking or derivatization reagent has the specified reactive group.
database_cross_reference: OBO:defs

is_activatable
type: ObjectProperty
definition: Indicates how the cross-linking reagent can be activated.
has_obo_namespace: XLMOD
id: is_activatable

Axiom
annotated source: is_activatable
annotated property: definition
annotated target: Indicates how the cross-linking reagent can be activated.
database_cross_reference: OBO:defs

is_analog_of
type: ObjectProperty
definition: Indicates biochemical analogues of nucleobases, nucleosides or amino acids.
has_obo_namespace: XLMOD
id: is_analog_of

Axiom
annotated source: is_analog_of
annotated property: definition
annotated target: Indicates biochemical analogues of nucleobases, nucleosides or amino acids.
database_cross_reference: OBO:defs

is_cleavable
type: ObjectProperty
definition: Indicates that the cross-linking reagent is cleavable.
has_obo_namespace: XLMOD
id: is_cleavable

Axiom
annotated source: is_cleavable
annotated property: definition
annotated target: Indicates that the cross-linking reagent is cleavable.
database_cross_reference: OBO:defs

is_labelled
type: ObjectProperty
definition: Indicates that the cross-linking or derivatization reagent has an isotopic label.
has_obo_namespace: XLMOD
id: is_labelled

Axiom
annotated source: is_labelled
annotated property: definition
annotated target: Indicates that the cross-linking or derivatization reagent has an isotopic label.
database_cross_reference: OBO:defs

is_partially_reacted
type: ObjectProperty
definition: Specifies the type of the cross-linker related chemical modification.
has_obo_namespace: XLMOD
id: is_partially_reacted

Axiom
annotated source: is_partially_reacted
annotated property: definition
annotated target: Specifies the type of the cross-linker related chemical modification.
database_cross_reference: OBO:defs

is_reactive_with
type: ObjectProperty
definition: Indicates the chemical group that can react with the cross-linking or derivatization reagent.
has_obo_namespace: XLMOD
id: is_reactive_with

Axiom
annotated source: is_reactive_with
annotated property: definition
annotated target: Indicates the chemical group that can react with the cross-linking or derivatization reagent.
database_cross_reference: OBO:defs

is_side_product_of
type: ObjectProperty
definition: Indicates the cross-linking reagent from which the chemical modification is derived.
has_obo_namespace: XLMOD
id: is_side_product_of

Axiom
annotated source: is_side_product_of
annotated property: definition
annotated target: Indicates the cross-linking reagent from which the chemical modification is derived.
database_cross_reference: OBO:defs

part_of
type: ObjectProperty
type: TransitiveProperty
definition: The basic part of relationship indicating a top-level branch of this ontology.
has_obo_namespace: XLMOD
id: part_of

Axiom
annotated source: part_of
annotated property: definition
annotated target: The basic part of relationship indicating a top-level branch of this ontology.
database_cross_reference: OBO:defs

Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary
type: Class
definition: Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary.
has_obo_namespace: XLMOD
id: XLMOD:00000

Axiom
annotated source: Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary
annotated property: definition
annotated target: Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary.
database_cross_reference: PSI:XL

cross-linking entity
type: Class
subclass of: Restriction
  on property: part_of
  some values from: Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary
definition: Entity relevant to the domain of cross-linking in proteomics.
has_obo_namespace: XLMOD
id: XLMOD:00001

Axiom
annotated source: cross-linking entity
annotated property: definition
annotated target: Entity relevant to the domain of cross-linking in proteomics.
database_cross_reference: PSI:XL

cross-linker related chemical modification
type: Class
subclass of: Restriction
  on property: part_of
  some values from: Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary
definition: Dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
has_obo_namespace: XLMOD
id: XLMOD:00002

Axiom
annotated source: cross-linker related chemical modification
annotated property: definition
annotated target: Dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
database_cross_reference: PSI:XL

label transfer reagent
type: Class
subclass of: Restriction
  on property: part_of
  some values from: Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary
definition: A cross-linker acting as label transfer reagent.
has_obo_namespace: XLMOD
id: XLMOD:00003

Axiom
annotated source: label transfer reagent
annotated property: definition
annotated target: A cross-linker acting as label transfer reagent.
database_cross_reference: PSI:XL

cross-linker
type: Class
subclass of: cross-linking entity
definition: Compound that can link two or more polymer chains.
has_obo_namespace: XLMOD
id: XLMOD:00004

Axiom
annotated source: cross-linker
annotated property: definition
annotated target: Compound that can link two or more polymer chains.
database_cross_reference: PSI:XL

homofunctional cross-linker
type: Class
subclass of: cross-linker
definition: A cross-linking reagent with identical reactive groups at each end of the spacer arm.
has_obo_namespace: XLMOD
id: XLMOD:00005

Axiom
annotated source: homofunctional cross-linker
annotated property: definition
annotated target: A cross-linking reagent with identical reactive groups at each end of the spacer arm.
database_cross_reference: PSI:XL

heterofunctional cross-linker
type: Class
subclass of: cross-linker
definition: A cross-linking reagent with at least two different reactive groups.
has_obo_namespace: XLMOD
id: XLMOD:00006

Axiom
annotated source: heterofunctional cross-linker
annotated property: definition
annotated target: A cross-linking reagent with at least two different reactive groups.
database_cross_reference: PSI:XL

photoreactive cross-linker
type: Class
definition: OBSOLETE A cross-linking reagent that becomes reactive when exposed to ultraviolet or visible light.
has_obo_namespace: XLMOD
id: XLMOD:00007
comment: This term was made obsolete because photo-reactivity is now encoded for the reactive groups of the cross-linkers, see (XLMOD:00108).
deprecated: true

Axiom
annotated source: photoreactive cross-linker
annotated property: definition
annotated target: OBSOLETE A cross-linking reagent that becomes reactive when exposed to ultraviolet or visible light.
database_cross_reference: PSI:XL

zero-length cross-linker
type: Class
subclass of: cross-linker
definition: A cross-linking reagent causing direct conjugation without becoming part of the final cross-link between the target molecules.
has_obo_namespace: XLMOD
id: XLMOD:00008

Axiom
annotated source: zero-length cross-linker
annotated property: definition
annotated target: A cross-linking reagent causing direct conjugation without becoming part of the final cross-link between the target molecules.
database_cross_reference: PSI:XL

cross-linking attribute
type: Class
subclass of: cross-linking entity
definition: An attribute describing a cross-linker.
has_obo_namespace: XLMOD
id: XLMOD:00009

Axiom
annotated source: cross-linking attribute
annotated property: definition
annotated target: An attribute describing a cross-linker.
database_cross_reference: PSI:XL

deuterium labelled
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is deuterium labelled.
has_obo_namespace: XLMOD
id: XLMOD:00010

Axiom
annotated source: deuterium labelled
annotated property: definition
annotated target: Indicates that a cross-linker is deuterium labelled.
database_cross_reference: PSI:XL

hydrolyzed
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is hydrolyzed, for example for NHS-type reagents -C(=O)-NHS was converted to -C(=O)-OH.
has_obo_namespace: XLMOD
id: XLMOD:00011

Axiom
annotated source: hydrolyzed
annotated property: definition
annotated target: Indicates that a cross-linker is hydrolyzed, for example for NHS-type reagents -C(=O)-NHS was converted to -C(=O)-OH.
database_cross_reference: PSI:XL

amidated
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is amidated.
has_obo_namespace: XLMOD
id: XLMOD:00012

Axiom
annotated source: amidated
annotated property: definition
annotated target: Indicates that a cross-linker is amidated.
database_cross_reference: PSI:XL

membrane permeable
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is membrane permeable.
has_obo_namespace: XLMOD
id: XLMOD:00013

Axiom
annotated source: membrane permeable
annotated property: definition
annotated target: Indicates that a cross-linker is membrane permeable.
database_cross_reference: PSI:XL

hydrophilic
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is hydrophilic.
has_obo_namespace: XLMOD
id: XLMOD:00014

Axiom
annotated source: hydrophilic
annotated property: definition
annotated target: Indicates that a cross-linker is hydrophilic.
database_cross_reference: PSI:XL

fluorescent
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is fluorescent.
has_obo_namespace: XLMOD
id: XLMOD:00015

Axiom
annotated source: fluorescent
annotated property: definition
annotated target: Indicates that a cross-linker is fluorescent.
database_cross_reference: PSI:XL

cleavable
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is cleavable.
has_obo_namespace: XLMOD
id: XLMOD:00016

Axiom
annotated source: cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is cleavable.
database_cross_reference: PSI:XL

chemically cleavable
type: Class
subclass of: cleavable
definition: Indicates that a cross-linker is chemically cleavable.
has_obo_namespace: XLMOD
id: XLMOD:00017

Axiom
annotated source: chemically cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable.
database_cross_reference: PSI:XL

cleavable by MS2 labile bond
type: Class
subclass of: cleavable
definition: Indicates that a cross-linker is mass-spectrometrically cleavable, i.e. contains a MS2 labile bond leading to fragments detected in MS3.
has_obo_namespace: XLMOD
id: XLMOD:00018

Axiom
annotated source: cleavable by MS2 labile bond
annotated property: definition
annotated target: Indicates that a cross-linker is mass-spectrometrically cleavable, i.e. contains a MS2 labile bond leading to fragments detected in MS3.
database_cross_reference: PSI:XL

enrichable
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker facilitates enrichment.
has_obo_namespace: XLMOD
id: XLMOD:00019

Axiom
annotated source: enrichable
annotated property: definition
annotated target: Indicates that a cross-linker facilitates enrichment.
database_cross_reference: PSI:XL

iodinatable
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is iodinatable, e.g. for autoradiographic detection by radio-labelling with J-131.
has_obo_namespace: XLMOD
id: XLMOD:00020

Axiom
annotated source: iodinatable
annotated property: definition
annotated target: Indicates that a cross-linker is iodinatable, e.g. for autoradiographic detection by radio-labelling with J-131.
database_cross_reference: PSI:XL

ammonium amidated
type: Class
subclass of: amidated
definition: Indicates a dead-end modification that was amidated by an ammonium salt, like e.g. bicarbonate, phosphate, chloride, for example for NHS-type reagents -C(=O)-NHS was converted to -C(=O)-NH2.
has_obo_namespace: XLMOD
id: XLMOD:00021

Axiom
annotated source: ammonium amidated
annotated property: definition
annotated target: Indicates a dead-end modification that was amidated by an ammonium salt, like e.g. bicarbonate, phosphate, chloride, for example for NHS-type reagents -C(=O)-NHS was converted to -C(=O)-NH2.
database_cross_reference: PSI:XL

Tris amidated
type: Class
subclass of: amidated
definition: Indicates a dead-end modification that was amidated by Tris(hydroxymethyl)-aminomethane, for example for NHS-type reagents -C(=O)-NHS was converted to -C(=O)-NHC(CH2OH)3.
has_obo_namespace: XLMOD
id: XLMOD:00022

Axiom
annotated source: Tris amidated
annotated property: definition
annotated target: Indicates a dead-end modification that was amidated by Tris(hydroxymethyl)-aminomethane, for example for NHS-type reagents -C(=O)-NHS was converted to -C(=O)-NHC(CH2OH)3.
database_cross_reference: PSI:XL

cleavable S-S bond
type: Class
subclass of: chemically cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: DTT cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: thiol cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: TCEP cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: mercaptoethanol cleavable
definition: Indicates that a cross-linker contains a cleavable S-S bond, which is chemically cleavable by reducing agents like e.g. thiols, beta-mercaptoethanol, dithiothreitol (DTT), mercaptomethylamine or Tris(2-carboxyethyl)phosphin (TCEP).
has_obo_namespace: XLMOD
id: XLMOD:00023

Axiom
annotated source: cleavable S-S bond
annotated property: definition
annotated target: Indicates that a cross-linker contains a cleavable S-S bond, which is chemically cleavable by reducing agents like e.g. thiols, beta-mercaptoethanol, dithiothreitol (DTT), mercaptomethylamine or Tris(2-carboxyethyl)phosphin (TCEP).
database_cross_reference: PSI:XL

periodate cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by the oxidizing agent periodate.
has_obo_namespace: XLMOD
id: XLMOD:00024

Axiom
annotated source: periodate cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by the oxidizing agent periodate.
database_cross_reference: PSI:XL

hydroxylamine cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by hydroxylamine.
has_obo_namespace: XLMOD
id: XLMOD:00025

Axiom
annotated source: hydroxylamine cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by hydroxylamine.
database_cross_reference: PSI:XL

reactive group attribute
type: Class
subclass of: Restriction
  on property: part_of
  some values from: cross-linking entity
definition: An attribute describing a reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00026

Axiom
annotated source: reactive group attribute
annotated property: definition
annotated target: An attribute describing a reactive group.
database_cross_reference: PSI:XL

chemically reactive
type: Class
subclass of: reactive group attribute
definition: Indicates that a reactive group reacts with specific functional groups.
has_obo_namespace: XLMOD
id: XLMOD:00027

Axiom
annotated source: chemically reactive
annotated property: definition
annotated target: Indicates that a reactive group reacts with specific functional groups.
database_cross_reference: PSI:XL

primary amine reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with primary amino (-NH2) groups.
has_obo_namespace: XLMOD
id: XLMOD:00028

Axiom
annotated source: primary amine reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with primary amino (-NH2) groups.
database_cross_reference: PSI:XL

sulfhydryl reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with sulfhydryl (-SH) groups.
has_obo_namespace: XLMOD
id: XLMOD:00029

Axiom
annotated source: sulfhydryl reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with sulfhydryl (-SH) groups.
database_cross_reference: PSI:XL

carboxyl reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with carboxyl (-COOH) groups.
has_obo_namespace: XLMOD
id: XLMOD:00030

Axiom
annotated source: carboxyl reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with carboxyl (-COOH) groups.
database_cross_reference: PSI:XL

aldehyde reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with aldehyde (-CHO) or carbonyl (-CO) groups.
has_obo_namespace: XLMOD
id: XLMOD:00031

Axiom
annotated source: aldehyde reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with aldehyde (-CHO) or carbonyl (-CO) groups.
database_cross_reference: PSI:XL

hydroxyl reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with hydroxyl (-OH) groups.
has_obo_namespace: XLMOD
id: XLMOD:00032

Axiom
annotated source: hydroxyl reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with hydroxyl (-OH) groups.
database_cross_reference: PSI:XL

azide reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with azide (-N3) groups.
has_obo_namespace: XLMOD
id: XLMOD:00033

Axiom
annotated source: azide reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with azide (-N3) groups.
database_cross_reference: PSI:XL

photo cleavable
type: Class
subclass of: cleavable
definition: Indicates that a cross-linker is cleavable by light.
has_obo_namespace: XLMOD
id: XLMOD:00034

Axiom
annotated source: photo cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is cleavable by light.
database_cross_reference: PSI:XL

CID cleavable
type: Class
subclass of: cleavable
definition: Indicates that a cross-linker is mass-spectrometrically cleavable by collission induced dissociation.
has_obo_namespace: XLMOD
id: XLMOD:00035

Axiom
annotated source: CID cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is mass-spectrometrically cleavable by collission induced dissociation.
database_cross_reference: PSI:XL

13C labelled
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is labelled with carbon-13.
has_obo_namespace: XLMOD
id: XLMOD:00036

Axiom
annotated source: 13C labelled
annotated property: definition
annotated target: Indicates that a cross-linker is labelled with carbon-13.
database_cross_reference: PSI:XL

non-selective
type: Class
subclass of: reactive group attribute
definition: Indicates that a cross-linker is non-selective (i.e. can react with different amino acids, but also with DNA/RNA and carbohydrates (aldehyde reactive)).
has_obo_namespace: XLMOD
id: XLMOD:00037

Axiom
annotated source: non-selective
annotated property: definition
annotated target: Indicates that a cross-linker is non-selective (i.e. can react with different amino acids, but also with DNA/RNA and carbohydrates (aldehyde reactive)).
database_cross_reference: PSI:XL

DTT cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by the reducing agent DTT (dithiothreitol).
has_obo_namespace: XLMOD
id: XLMOD:00038

Axiom
annotated source: DTT cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by the reducing agent DTT (dithiothreitol).
database_cross_reference: PSI:XL

ammonium cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by ammonium hydroxide.
has_obo_namespace: XLMOD
id: XLMOD:00039

Axiom
annotated source: ammonium cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by ammonium hydroxide.
database_cross_reference: PSI:XL

ISD cleavable
type: Class
subclass of: cleavable
definition: Indicates that a cross-linker is mass-spectrometrically cleavable by in-source decay.
has_obo_namespace: XLMOD
id: XLMOD:00040

Axiom
annotated source: ISD cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is mass-spectrometrically cleavable by in-source decay.
database_cross_reference: PSI:XL

thiol cleavable
type: Class
subclass of: cleavable
definition: Indicates that a cross-linker is mass-spectrometrically cleavable (reducible) by thiols.
has_obo_namespace: XLMOD
has_related_synonym: DTT cleavable
has_related_synonym: TCEP cleavable
has_related_synonym: mercaptoethanol cleavable
id: XLMOD:00041

Axiom
annotated source: thiol cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is mass-spectrometrically cleavable (reducible) by thiols.
database_cross_reference: PSI:XL

TCEP cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by the reducing agent TCEP (Tris(2-carboxyethyl)phosphin).
has_obo_namespace: XLMOD
id: XLMOD:00042

Axiom
annotated source: TCEP cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by the reducing agent TCEP (Tris(2-carboxyethyl)phosphin).
database_cross_reference: PSI:XL

mercaptoethanol cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by the reducing agent mercaptoethanol.
has_obo_namespace: XLMOD
id: XLMOD:00043

Axiom
annotated source: mercaptoethanol cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by the reducing agent mercaptoethanol.
database_cross_reference: PSI:XL

mass defect labelled
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is mass defect labelled.
has_obo_namespace: XLMOD
id: XLMOD:00044

Axiom
annotated source: mass defect labelled
annotated property: definition
annotated target: Indicates that a cross-linker is mass defect labelled.
database_cross_reference: PSI:XL

thioether reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with thioether (R1-S-R2) groups.
has_obo_namespace: XLMOD
id: XLMOD:00045

Axiom
annotated source: thioether reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with thioether (R1-S-R2) groups.
database_cross_reference: PSI:XL

imidazole reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with the heterocyclic imidazole groups.
has_obo_namespace: XLMOD
id: XLMOD:00046

Axiom
annotated source: imidazole reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with the heterocyclic imidazole groups.
database_cross_reference: PSI:XL

thioesterized
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is thioesterized.
has_obo_namespace: XLMOD
id: XLMOD:00047

Axiom
annotated source: thioesterized
annotated property: definition
annotated target: Indicates that a cross-linker is thioesterized.
database_cross_reference: PSI:XL

nucleic acid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with RNA or DNA.
has_obo_namespace: XLMOD
id: XLMOD:00048

Axiom
annotated source: nucleic acid reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with RNA or DNA.
database_cross_reference: PSI:XL

amino acid derivative
type: Class
subclass of: cross-linking entity
definition: An amino acid derivative used in cross-linking experiments.
has_obo_namespace: XLMOD
id: XLMOD:00049

Axiom
annotated source: amino acid derivative
annotated property: definition
annotated target: An amino acid derivative used in cross-linking experiments.
database_cross_reference: PSI:XL

handle
type: Class
subclass of: cross-linking entity
subclass of: Restriction
  on property: part_of
  some values from: cross-linker
definition: A handle attached to a cross-linker used for detection, affinity enrichment or purification.
has_obo_namespace: XLMOD
id: XLMOD:00050

Axiom
annotated source: handle
annotated property: definition
annotated target: A handle attached to a cross-linker used for detection, affinity enrichment or purification.
database_cross_reference: PSI:XL

biotin
type: Class
subclass of: enrichable
subclass of: handle
definition: A Biotin affinity handle, enrichable with avidin, streptavidin or neutravidin, attached to a cross-linker.
has_obo_namespace: XLMOD
id: XLMOD:00051

Axiom
annotated source: biotin
annotated property: definition
annotated target: A Biotin affinity handle, enrichable with avidin, streptavidin or neutravidin, attached to a cross-linker.
database_cross_reference: PSI:XL

NO2 neutral loss reporter
type: Class
subclass of: handle
definition: A NO2 detection tag.
has_obo_namespace: XLMOD
id: XLMOD:00052

Axiom
annotated source: NO2 neutral loss reporter
annotated property: definition
annotated target: A NO2 detection tag.
database_cross_reference: PMID:19496583

alkyne
type: Class
subclass of: enrichable
subclass of: handle
definition: An alkyne (hadrocarbon with at least one C-C triple bond) tag, e.g. BARAC (biarylazacycloctynone) to enable enrichment of cross-linked peptides by either coupling of an affinity group with alkyne-azido click chemistry or by using immobilized azide linkers.
has_obo_namespace: XLMOD
id: XLMOD:00053

Axiom
annotated source: alkyne
annotated property: definition
annotated target: An alkyne (hadrocarbon with at least one C-C triple bond) tag, e.g. BARAC (biarylazacycloctynone) to enable enrichment of cross-linked peptides by either coupling of an affinity group with alkyne-azido click chemistry or by using immobilized azide linkers.
database_cross_reference: PMID:19496583

DNB
type: Class
subclass of: enrichable
subclass of: handle
definition: A dinitrobenzole affinity handle for enrichment with anti-DNB antibodies, attached to a cross-linker.
has_obo_namespace: XLMOD
id: XLMOD:00054

Axiom
annotated source: DNB
annotated property: definition
annotated target: A dinitrobenzole affinity handle for enrichment with anti-DNB antibodies, attached to a cross-linker.
database_cross_reference: PSI:XL

azide
type: Class
subclass of: enrichable
subclass of: handle
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: A photoreactive azide (-N3) tag to enable enrichment of cross-linked peptides with either immobilized alkyne linkers or by azide-alkyne click chemistry using biotin-alkyne respective biotin-phosphine.
has_obo_namespace: XLMOD
id: XLMOD:00055

Axiom
annotated source: azide
annotated property: definition
annotated target: A photoreactive azide (-N3) tag to enable enrichment of cross-linked peptides with either immobilized alkyne linkers or by azide-alkyne click chemistry using biotin-alkyne respective biotin-phosphine.
database_cross_reference: PMID:20472459

CHCA
type: Class
subclass of: handle
definition: An alpha-cyano-4-hydroxycinnamic acid UV-absorbing label for signal enhancement.
has_obo_namespace: XLMOD
id: XLMOD:00056

Axiom
annotated source: CHCA
annotated property: definition
annotated target: An alpha-cyano-4-hydroxycinnamic acid UV-absorbing label for signal enhancement.
database_cross_reference: PMID:19902427

generic neutral loss reporter
type: Class
subclass of: handle
definition: A generic neutral loss reporter.
has_obo_namespace: XLMOD
id: XLMOD:00057

Axiom
annotated source: generic neutral loss reporter
annotated property: definition
annotated target: A generic neutral loss reporter.
database_cross_reference: PXI:XL

amino acid
type: Class
subclass of: cross-linking entity
definition: An amino acid compound.
has_obo_namespace: XLMOD
id: XLMOD:00058

Axiom
annotated source: amino acid
annotated property: definition
annotated target: An amino acid compound.
database_cross_reference: PSI:XL

L-Leucine
type: Class
subclass of: amino acid
definition: The amino acid L-Leucine.
has_obo_namespace: XLMOD
id: XLMOD:00059

Axiom
annotated source: L-Leucine
annotated property: definition
annotated target: The amino acid L-Leucine.
database_cross_reference: PXI:XL

L-Methionine
type: Class
subclass of: amino acid
definition: The amino acid L-Methionine.
has_obo_namespace: XLMOD
id: XLMOD:00060

Axiom
annotated source: L-Methionine
annotated property: definition
annotated target: The amino acid L-Methionine.
database_cross_reference: PXI:XL

base cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by bases.
has_obo_namespace: XLMOD
id: XLMOD:00061

Axiom
annotated source: base cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by bases.
database_cross_reference: PSI:XL

hydrazine reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with hydrazines (N2H4).
has_obo_namespace: XLMOD
id: XLMOD:00062

Axiom
annotated source: hydrazine reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with hydrazines (N2H4).
database_cross_reference: PSI:XL

carbonyl reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with carbonyl (R1-CO-R2) groups.
has_obo_namespace: XLMOD
id: XLMOD:00063

Axiom
annotated source: carbonyl reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with carbonyl (R1-CO-R2) groups.
database_cross_reference: PSI:XL

oxidized
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is oxidized, e.g. by oxidizing a carbonyl to a carboxyl functional group.
has_obo_namespace: XLMOD
id: XLMOD:00064

Axiom
annotated source: oxidized
annotated property: definition
annotated target: Indicates that a cross-linker is oxidized, e.g. by oxidizing a carbonyl to a carboxyl functional group.
database_cross_reference: PSI:XL

alkenized
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is modified to it's alkene form (loss of two hydrogen atoms by forming a C=C double bond).
has_obo_namespace: XLMOD
id: XLMOD:00065

Axiom
annotated source: alkenized
annotated property: definition
annotated target: Indicates that a cross-linker is modified to it's alkene form (loss of two hydrogen atoms by forming a C=C double bond).
database_cross_reference: PSI:XL

acid cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by acids.
has_obo_namespace: XLMOD
id: XLMOD:00066

Axiom
annotated source: acid cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by acids.
database_cross_reference: PSI:XL

CID cleavable C-S bond
type: Class
subclass of: CID cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable by MS2 labile bond
definition: Indicates that a cross-linker contains a CID (Collision Induced Dissociation) cleavable C-S bond.
has_obo_namespace: XLMOD
id: XLMOD:00067

Axiom
annotated source: CID cleavable C-S bond
annotated property: definition
annotated target: Indicates that a cross-linker contains a CID (Collision Induced Dissociation) cleavable C-S bond.
database_cross_reference: PSI:XL

L-Isoleucine
type: Class
subclass of: amino acid
definition: The amino acid L-Isoleucine.
has_obo_namespace: XLMOD
id: XLMOD:00068

Axiom
annotated source: L-Isoleucine
annotated property: definition
annotated target: The amino acid L-Isoleucine.
database_cross_reference: PXI:XL

18O labelled
type: Class
subclass of: cross-linking attribute
definition: Indicates that a cross-linker is labelled with oxygen-18.
has_obo_namespace: XLMOD
id: XLMOD:00069

Axiom
annotated source: 18O labelled
annotated property: definition
annotated target: Indicates that a cross-linker is labelled with oxygen-18.
database_cross_reference: PSI:XL

L-Phenylalanine
type: Class
subclass of: amino acid
definition: The amino acid L-Phenylalanine.
has_obo_namespace: XLMOD
id: XLMOD:00070

Axiom
annotated source: L-Phenylalanine
annotated property: definition
annotated target: The amino acid L-Phenylalanine.
database_cross_reference: PXI:XL

iminobiotintrifluoroacetamide
type: Class
subclass of: enrichable
subclass of: handle
subclass of: Restriction
  on property: is_reactive_with
  some values from: avidin reactive
definition: A Iminobiotin trifluoroacetamide affinity handle, enrichable with avidin, streptavidin or neutravidin, attached to a cross-linker.
has_obo_namespace: XLMOD
id: XLMOD:00071

Axiom
annotated source: iminobiotintrifluoroacetamide
annotated property: definition
annotated target: A Iminobiotin trifluoroacetamide affinity handle, enrichable with avidin, streptavidin or neutravidin, attached to a cross-linker.
database_cross_reference: PSI:XL

avidin reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with either of the glycoproteins avidin, streptavidin or neutravidin.
has_obo_namespace: XLMOD
id: XLMOD:00072

Axiom
annotated source: avidin reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with either of the glycoproteins avidin, streptavidin or neutravidin.
database_cross_reference: PSI:XL

nucleobase
type: Class
subclass of: cross-linking entity
definition: A nitrogeneous base occurring in nucleic acids.
has_obo_namespace: XLMOD
id: XLMOD:00073

Axiom
annotated source: nucleobase
annotated property: definition
annotated target: A nitrogeneous base occurring in nucleic acids.
database_cross_reference: PSI:XL

purine base
type: Class
subclass of: nucleobase
definition: A purine base occurring in nucleic acids.
has_obo_namespace: XLMOD
id: XLMOD:00074

Axiom
annotated source: purine base
annotated property: definition
annotated target: A purine base occurring in nucleic acids.
database_cross_reference: PSI:XL

pyrimidine base
type: Class
subclass of: nucleobase
definition: A pyrimidine base occurring in nucleic acids.
has_obo_namespace: XLMOD
id: XLMOD:00075

Axiom
annotated source: pyrimidine base
annotated property: definition
annotated target: A pyrimidine base occurring in nucleic acids.
database_cross_reference: PSI:XL

adenine
type: Class
subclass of: purine base
definition: The nucleobase adenine.
has_obo_namespace: XLMOD
id: XLMOD:00076

Axiom
annotated source: adenine
annotated property: definition
annotated target: The nucleobase adenine.
database_cross_reference: PXI:XL

guanine
type: Class
subclass of: purine base
definition: The nucleobase guanine.
has_obo_namespace: XLMOD
id: XLMOD:00077

Axiom
annotated source: guanine
annotated property: definition
annotated target: The nucleobase guanine.
database_cross_reference: PXI:XL

cytosine
type: Class
subclass of: pyrimidine base
definition: The nucleobase cytosine.
has_obo_namespace: XLMOD
id: XLMOD:00078

Axiom
annotated source: cytosine
annotated property: definition
annotated target: The nucleobase cytosine.
database_cross_reference: PXI:XL

thymine
type: Class
subclass of: pyrimidine base
definition: The nucleobase thymine.
has_obo_namespace: XLMOD
id: XLMOD:00079

Axiom
annotated source: thymine
annotated property: definition
annotated target: The nucleobase thymine.
database_cross_reference: PXI:XL

uracil
type: Class
subclass of: pyrimidine base
definition: The nucleobase uracil.
has_obo_namespace: XLMOD
id: XLMOD:00080

Axiom
annotated source: uracil
annotated property: definition
annotated target: The nucleobase uracil.
database_cross_reference: PXI:XL

nucleobase derivative
type: Class
subclass of: cross-linking entity
subclass of: Restriction
  on property: is_analog_of
  some values from: nucleobase
definition: A nucleobase derivative used in cross-linking experiments for protein-oligonucleotide cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:00081

Axiom
annotated source: nucleobase derivative
annotated property: definition
annotated target: A nucleobase derivative used in cross-linking experiments for protein-oligonucleotide cross-linking.
database_cross_reference: PSI:XL

nucleoside
type: Class
subclass of: cross-linking entity
definition: A combination of a nucleobase and a sugar (either ribose or deoxyribose).
has_obo_namespace: XLMOD
id: XLMOD:00082

Axiom
annotated source: nucleoside
annotated property: definition
annotated target: A combination of a nucleobase and a sugar (either ribose or deoxyribose).
database_cross_reference: PSI:XL

adenosine
type: Class
subclass of: nucleoside
definition: The nucleoside adenosine.
has_obo_namespace: XLMOD
id: XLMOD:00083

Axiom
annotated source: adenosine
annotated property: definition
annotated target: The nucleoside adenosine.
database_cross_reference: PXI:XL

guanosine
type: Class
subclass of: nucleoside
definition: The nucleoside guanosine.
has_obo_namespace: XLMOD
id: XLMOD:00084

Axiom
annotated source: guanosine
annotated property: definition
annotated target: The nucleoside guanosine.
database_cross_reference: PXI:XL

cytidine
type: Class
subclass of: nucleoside
definition: The nucleoside cytidine.
has_obo_namespace: XLMOD
id: XLMOD:00085

Axiom
annotated source: cytidine
annotated property: definition
annotated target: The nucleoside cytidine.
database_cross_reference: PXI:XL

uridine
type: Class
subclass of: nucleoside
definition: The nucleoside uridine.
has_obo_namespace: XLMOD
id: XLMOD:00086

Axiom
annotated source: uridine
annotated property: definition
annotated target: The nucleoside uridine.
database_cross_reference: PXI:XL

5-methyluridine
type: Class
subclass of: nucleoside
definition: The nucleoside 5-methyluridine.
has_obo_namespace: XLMOD
id: XLMOD:00087

Axiom
annotated source: 5-methyluridine
annotated property: definition
annotated target: The nucleoside 5-methyluridine.
database_cross_reference: PXI:XL

nucleoside derivative
type: Class
subclass of: cross-linking entity
subclass of: Restriction
  on property: is_analog_of
  some values from: nucleoside
definition: A nucleoside derivative used in cross-linking experiments for protein-oligonucleotide cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:00088

Axiom
annotated source: nucleoside derivative
annotated property: definition
annotated target: A nucleoside derivative used in cross-linking experiments for protein-oligonucleotide cross-linking.
database_cross_reference: PSI:XL

RNA-SH
type: Class
subclass of: cross-linking entity
definition: Thiol-modified RNA.
has_obo_namespace: XLMOD
id: XLMOD:00089

Axiom
annotated source: RNA-SH
annotated property: definition
annotated target: Thiol-modified RNA.
database_cross_reference: PSI:XL

biotin-alkyne
type: Class
subclass of: enrichable
subclass of: handle
subclass of: Restriction
  on property: is_reactive_with
  some values from: azide reactive
definition: A biotin-alkyne affinity handle, which can be used for enrichment with click-chemistry.
has_obo_namespace: XLMOD
id: XLMOD:00090

Axiom
annotated source: biotin-alkyne
annotated property: definition
annotated target: A biotin-alkyne affinity handle, which can be used for enrichment with click-chemistry.
database_cross_reference: PSI:XL

tetramethylrhodamine-alkyne
type: Class
subclass of: enrichable
subclass of: handle
subclass of: Restriction
  on property: is_reactive_with
  some values from: azide reactive
definition: A tetramethylrhodamine-alkyne affinity handle, which can be used for enrichment with click-chemistry.
has_exact_synonym: TAMRA
has_obo_namespace: XLMOD
id: XLMOD:00091

Axiom
annotated source: tetramethylrhodamine-alkyne
annotated property: definition
annotated target: A tetramethylrhodamine-alkyne affinity handle, which can be used for enrichment with click-chemistry.
database_cross_reference: PSI:XL

lipid analogue
type: Class
subclass of: cross-linking entity
definition: A lipid analogue used in cross-linking experiments for lipid-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:00092

Axiom
annotated source: lipid analogue
annotated property: definition
annotated target: A lipid analogue used in cross-linking experiments for lipid-protein cross-linking.
database_cross_reference: PSI:XL

sialic acid analogue
type: Class
subclass of: cross-linking entity
definition: A sialic acid analogue used in cross-linking experiments for glycan-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:00093

Axiom
annotated source: sialic acid analogue
annotated property: definition
annotated target: A sialic acid analogue used in cross-linking experiments for glycan-protein cross-linking.
database_cross_reference: PSI:XL

alkenized cross-linker related chemical modification
type: Class
subclass of: cross-linker related chemical modification
definition: Alkenization dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
has_obo_namespace: XLMOD
id: XLMOD:00094

Axiom
annotated source: alkenized cross-linker related chemical modification
annotated property: definition
annotated target: Alkenization dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
database_cross_reference: PSI:XL

ammonium amidation cross-linker related chemical modification
type: Class
subclass of: cross-linker related chemical modification
definition: Ammonium amidation dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
has_obo_namespace: XLMOD
id: XLMOD:00095

Axiom
annotated source: ammonium amidation cross-linker related chemical modification
annotated property: definition
annotated target: Ammonium amidation dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
database_cross_reference: PSI:XL

hydrolization cross-linker related chemical modification
type: Class
subclass of: cross-linker related chemical modification
definition: Hydrolization dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
has_obo_namespace: XLMOD
id: XLMOD:00096

Axiom
annotated source: hydrolization cross-linker related chemical modification
annotated property: definition
annotated target: Hydrolization dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
database_cross_reference: PSI:XL

oxidation cross-linker related chemical modification
type: Class
subclass of: cross-linker related chemical modification
definition: Oxidition dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
has_obo_namespace: XLMOD
id: XLMOD:00097

Axiom
annotated source: oxidation cross-linker related chemical modification
annotated property: definition
annotated target: Oxidition dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
database_cross_reference: PSI:XL

thioesterization cross-linker related chemical modification
type: Class
subclass of: cross-linker related chemical modification
definition: Thio-esterization dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
has_obo_namespace: XLMOD
id: XLMOD:00098

Axiom
annotated source: thioesterization cross-linker related chemical modification
annotated property: definition
annotated target: Thio-esterization dead-end modification resulting from a cross-linker reagent reacting only with one peptide.
database_cross_reference: PSI:XL

formic acid cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by formic acid.
has_obo_namespace: XLMOD
id: XLMOD:00099

Axiom
annotated source: formic acid cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by formic acid.
database_cross_reference: PSI:XL

reactive group
type: Class
subclass of: cross-linking attribute
definition: Part of a cross-linker that reacts with the amino-acids of the protein.
has_obo_namespace: XLMOD
id: XLMOD:00100

Axiom
annotated source: reactive group
annotated property: definition
annotated target: Part of a cross-linker that reacts with the amino-acids of the protein.
database_cross_reference: PSI:XL

NHS ester
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group (N-hydroxysuccinimide) that reacts with lysines and N-termini but also serines, threonines and tyrosines.
secondary specificities: (S,T,Y)
specificities: (K,Protein N-term)
has_exact_synonym: N-hydroxysuccinimide ester
has_obo_namespace: XLMOD
id: XLMOD:00101

Axiom
annotated source: NHS ester
annotated property: definition
annotated target: A reactive group (N-hydroxysuccinimide) that reacts with lysines and N-termini but also serines, threonines and tyrosines.
database_cross_reference: PSI:XL

Sulfo NHS ester
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group (N-hydroxysulfosuccinimide) that reacts with lysines and N-termini but also serines, threonines and tyrosines.
secondary specificities: (S,T,Y)
specificities: (K,Protein N-term)
has_exact_synonym: N-hydroxysulfosuccinimide ester
has_obo_namespace: XLMOD
id: XLMOD:00102

Axiom
annotated source: Sulfo NHS ester
annotated property: definition
annotated target: A reactive group (N-hydroxysulfosuccinimide) that reacts with lysines and N-termini but also serines, threonines and tyrosines.
database_cross_reference: PSI:XL

diazirine
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: Photoreactive group (R1-CN2-R2) that inserts into any C-H or N-H bond.
wave length range: 330-370 nm
has_obo_namespace: XLMOD
id: XLMOD:00103

Axiom
annotated source: diazirine
annotated property: definition
annotated target: Photoreactive group (R1-CN2-R2) that inserts into any C-H or N-H bond.
database_cross_reference: PSI:XL

N-hydroxyphthalimide
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group that reacts with amines.
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00104

Axiom
annotated source: N-hydroxyphthalimide
annotated property: definition
annotated target: A reactive group that reacts with amines.
database_cross_reference: PMID:19994840

carbodiimide
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: A Carboxyl-to-amine (R1-N=C=N_R2) reactive chemical group.
specificities: (K,N,Q,R,Protein N-term)&(E,D,Protein C-term)
has_obo_namespace: XLMOD
id: XLMOD:00105

Axiom
annotated source: carbodiimide
annotated property: definition
annotated target: A Carboxyl-to-amine (R1-N=C=N_R2) reactive chemical group.
database_cross_reference: PSI:XL

maleimide
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: A reactive group that reacts with sulfhydryl groups.
specificities: (C)
has_obo_namespace: XLMOD
id: XLMOD:00106

Axiom
annotated source: maleimide
annotated property: definition
annotated target: A reactive group that reacts with sulfhydryl groups.
database_cross_reference: PSI:XL

nitrophenyl azide
type: Class
subclass of: aryl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
subclass of: Restriction
  on property: is_reactive_with
  some values from: RNA-SH
definition: A nitrophenyl azide photoreactive group.
wave length range: 320-370 nm
has_obo_namespace: XLMOD
id: XLMOD:00107

Axiom
annotated source: nitrophenyl azide
annotated property: definition
annotated target: A nitrophenyl azide photoreactive group.
database_cross_reference: PSI:XL

photoreactive
type: Class
subclass of: reactive group attribute
definition: Indicates that a reactive group is photoreactive.
has_obo_namespace: XLMOD
id: XLMOD:00108

Axiom
annotated source: photoreactive
annotated property: definition
annotated target: Indicates that a reactive group is photoreactive.
database_cross_reference: PSI:XL

pyridinyldisulfide
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: A pyridinyldisulfide reactive group that reacts with sulfhydryl groups to form disulfide bonds.
specificities: (C)
has_exact_synonym: pyridyl disulfide
has_exact_synonym: pyridyldithiol
has_obo_namespace: XLMOD
id: XLMOD:00109

Axiom
annotated source: pyridinyldisulfide
annotated property: definition
annotated target: A pyridinyldisulfide reactive group that reacts with sulfhydryl groups to form disulfide bonds.
database_cross_reference: PSI:XL

hydrazide
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: A hydrazide reactive group (-CO-NH-NH2) that reacts with carbonyls to form hydrazone bonds.
specificities: (D,E,Protein C-term)
has_obo_namespace: XLMOD
id: XLMOD:00110

Axiom
annotated source: hydrazide
annotated property: definition
annotated target: A hydrazide reactive group (-CO-NH-NH2) that reacts with carbonyls to form hydrazone bonds.
database_cross_reference: PSI:XL

imidoester
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: An amine-reactive chemical group (R1-C(=NH)-OR2).
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00111

Axiom
annotated source: imidoester
annotated property: definition
annotated target: An amine-reactive chemical group (R1-C(=NH)-OR2).
database_cross_reference: PSI:XL

haloacetyl
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: A reactive group (alpha-haloacetyl, halo-C2H5), mostly a iodoacetyl, bromoacetyl or chloroacetyl group, that reacts with sulfhydryl groups.
specificities: (C)
has_obo_namespace: XLMOD
id: XLMOD:00112

Axiom
annotated source: haloacetyl
annotated property: definition
annotated target: A reactive group (alpha-haloacetyl, halo-C2H5), mostly a iodoacetyl, bromoacetyl or chloroacetyl group, that reacts with sulfhydryl groups.
database_cross_reference: PSI:XL

alkoxyamine
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
definition: A reactive group (R-O-N-R2) that conjugates to carbonyls.
specificities: (D,E,Protein C-term)
has_obo_namespace: XLMOD
id: XLMOD:00113

Axiom
annotated source: alkoxyamine
annotated property: definition
annotated target: A reactive group (R-O-N-R2) that conjugates to carbonyls.
database_cross_reference: PSI:XL

aryl azide
type: Class
subclass of: azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: Photoreactive aryl(Ar)-substitited azide (N=N=N) group, that initiates addition reactions with double bonds or insertion into C-H and N-H bonds or reacts with primary amines.
wave length range: 250-350 nm
has_obo_namespace: XLMOD
id: XLMOD:00114

Axiom
annotated source: aryl azide
annotated property: definition
annotated target: Photoreactive aryl(Ar)-substitited azide (N=N=N) group, that initiates addition reactions with double bonds or insertion into C-H and N-H bonds or reacts with primary amines.
database_cross_reference: PSI:XL

glyoxal
type: Class
subclass of: reactive group
definition: An arginine-specific reactive group (H-CO-CO-H).
base specificities: (Guanine)
specificities: (R)
has_obo_namespace: XLMOD
id: XLMOD:00115

Axiom
annotated source: glyoxal
annotated property: definition
annotated target: An arginine-specific reactive group (H-CO-CO-H).
database_cross_reference: PSI:XL

aldehyde group
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: An aldehyde (R-CO-H) reactive group.
secondary specificities: (C,F,H,S,T,W)
specificities: (K,N,R,Q,Y,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00116

Axiom
annotated source: aldehyde group
annotated property: definition
annotated target: An aldehyde (R-CO-H) reactive group.
database_cross_reference: PSI:XL

acryl
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: A reactive group (CH2=CH-CO-R) that reacts with sulfhydryl (-SH) groups.
specificities: (C)
has_obo_namespace: XLMOD
id: XLMOD:00117

Axiom
annotated source: acryl
annotated property: definition
annotated target: A reactive group (CH2=CH-CO-R) that reacts with sulfhydryl (-SH) groups.
database_cross_reference: PMID:22641729

tetrafluorophenyl azide
type: Class
subclass of: aryl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: Tetrafluorophenyl (TFP) azide (N=N=N) photoreactive group.
has_obo_namespace: XLMOD
id: XLMOD:00118

Axiom
annotated source: tetrafluorophenyl azide
annotated property: definition
annotated target: Tetrafluorophenyl (TFP) azide (N=N=N) photoreactive group.
database_cross_reference: PMID:22641729

benzophenone
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
subclass of: Restriction
  on property: is_reactive_with
  some values from: RNA-SH
definition: Benzophenone photoreactive group.
wave length range: 350-360 nm
has_obo_namespace: XLMOD
id: XLMOD:00119

Axiom
annotated source: benzophenone
annotated property: definition
annotated target: Benzophenone photoreactive group.
database_cross_reference: PMID:22641729

pentafluorophenyl
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group (F5-Ph) that reacts with amines.
specificities: (K,N,Q,R,Protein N-term)
has_exact_synonym: PFP ester
has_obo_namespace: XLMOD
id: XLMOD:00120

Axiom
annotated source: pentafluorophenyl
annotated property: definition
annotated target: A reactive group (F5-Ph) that reacts with amines.
database_cross_reference: PMID:22067100

methanethiosulfonate
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: A reactive group (Ch3-SO2-S-R) that reacts with sulfhydryl (-SH) groups.
specificities: (C)
has_exact_synonym: MTS
has_obo_namespace: XLMOD
id: XLMOD:00121

Axiom
annotated source: methanethiosulfonate
annotated property: definition
annotated target: A reactive group (Ch3-SO2-S-R) that reacts with sulfhydryl (-SH) groups.
database_cross_reference: PSI:XL

4-azido-2,3,5,6-tetrafluorobenzene
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: Photoreactive group that inserts into any C-H bond.
wave length range: UV
has_exact_synonym: ATFB
has_obo_namespace: XLMOD
id: XLMOD:00122

Axiom
annotated source: 4-azido-2,3,5,6-tetrafluorobenzene
annotated property: definition
annotated target: Photoreactive group that inserts into any C-H bond.
database_cross_reference: PSI:XL

thermoreactive
type: Class
subclass of: reactive group attribute
definition: Indicates that a reactive group is thermoreactive.
has_obo_namespace: XLMOD
id: XLMOD:00123

Axiom
annotated source: thermoreactive
annotated property: definition
annotated target: Indicates that a reactive group is thermoreactive.
database_cross_reference: PSI:XL

isocyanate
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
definition: An isocyanate (-N=C=O) that reacts with hydroxyl groups.
specificities: (S,T,Y)
has_obo_namespace: XLMOD
id: XLMOD:00124

Axiom
annotated source: isocyanate
annotated property: definition
annotated target: An isocyanate (-N=C=O) that reacts with hydroxyl groups.
database_cross_reference: PMID:21557289

hydroxyphenyl azide
type: Class
subclass of: aryl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: A hydroxyphenyl azid photoreactive group.
wave length range: 320-350 nm
has_obo_namespace: XLMOD
id: XLMOD:00125

Axiom
annotated source: hydroxyphenyl azide
annotated property: definition
annotated target: A hydroxyphenyl azid photoreactive group.
database_cross_reference: PSI:XL

phenyl azide
type: Class
subclass of: aryl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: A phenyl azide photoreactive group.
wave length range: 320-350 nm
has_exact_synonym: aryl nitrene
has_obo_namespace: XLMOD
id: XLMOD:00126

Axiom
annotated source: phenyl azide
annotated property: definition
annotated target: A phenyl azide photoreactive group.
database_cross_reference: PSI:XL

iodoacetyl
type: Class
subclass of: haloacetyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: A iodoacetyl reactive group, that reacts with sulfhydryl groups.
specificities: (C,H)
has_obo_namespace: XLMOD
id: XLMOD:00127

Axiom
annotated source: iodoacetyl
annotated property: definition
annotated target: A iodoacetyl reactive group, that reacts with sulfhydryl groups.
database_cross_reference: PSI:XL

bromoacetyl
type: Class
subclass of: haloacetyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: A bromoacetyl reactive group, that reacts with sulfhydryl groups.
specificities: (C,H)
has_obo_namespace: XLMOD
id: XLMOD:00128

Axiom
annotated source: bromoacetyl
annotated property: definition
annotated target: A bromoacetyl reactive group, that reacts with sulfhydryl groups.
database_cross_reference: PSI:XL

hydroxybenzotriazole
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group that reacts with amines.
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00129

Axiom
annotated source: hydroxybenzotriazole
annotated property: definition
annotated target: A reactive group that reacts with amines.
database_cross_reference: PMID:19994840

1-hydroxy-7-azabenzotriazole
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group that reacts with amines.
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00130

Axiom
annotated source: 1-hydroxy-7-azabenzotriazole
annotated property: definition
annotated target: A reactive group that reacts with amines.
database_cross_reference: PMID:19994840

thioimidate
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group that reacts with amines.
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00131

Axiom
annotated source: thioimidate
annotated property: definition
annotated target: A reactive group that reacts with amines.
database_cross_reference: PMID:20795639

platinum(II)
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: thioether reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: imidazole reactive
definition: Platinum(II) coordinates with the side chains of methionine (Met), cysteine (Cys), and histidine(His), namely, thioether, sulfhydryl, and imidazole.
base specificities: (Guanine)
secondary base specificities: (Adenine, Cytosine)
specificities: (C,H,M)
has_obo_namespace: XLMOD
id: XLMOD:00132

Axiom
annotated source: platinum(II)
annotated property: definition
annotated target: Platinum(II) coordinates with the side chains of methionine (Met), cysteine (Cys), and histidine(His), namely, thioether, sulfhydryl, and imidazole.
database_cross_reference: PMID:21591778

amine reactive group
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: Reactive group (-NH2) that reacts with carboxyl (-COOH) groups.
specificities: (D,E)
has_obo_namespace: XLMOD
id: XLMOD:00133

Axiom
annotated source: amine reactive group
annotated property: definition
annotated target: Reactive group (-NH2) that reacts with carboxyl (-COOH) groups.
database_cross_reference: PSI:XL

psoralen
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: nucleic acid reactive
definition: A photoreactive group that reacts with pyrimidines, especially thymines of nucleic acids.
specificities: (Thy)
has_obo_namespace: XLMOD
id: XLMOD:00134

Axiom
annotated source: psoralen
annotated property: definition
annotated target: A photoreactive group that reacts with pyrimidines, especially thymines of nucleic acids.
database_cross_reference: PSI:XL

azido-methylcoumarin
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: A photoreactive azido-methylcoumarin group.
has_obo_namespace: XLMOD
id: XLMOD:00135

Axiom
annotated source: azido-methylcoumarin
annotated property: definition
annotated target: A photoreactive azido-methylcoumarin group.
database_cross_reference: PSI:XL

perfluoroaryl azide
type: Class
subclass of: aryl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: A photoreactive perfluoroaryl azide group.
has_obo_namespace: XLMOD
id: XLMOD:00136

Axiom
annotated source: perfluoroaryl azide
annotated property: definition
annotated target: A photoreactive perfluoroaryl azide group.
database_cross_reference: PSI:XL

diazo group
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: A photoreactive diazo (R1R2C=N=N) group.
has_obo_namespace: XLMOD
id: XLMOD:00137

Axiom
annotated source: diazo group
annotated property: definition
annotated target: A photoreactive diazo (R1R2C=N=N) group.
database_cross_reference: PSI:XL

carboxyl
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group (-COOH) that reacts with primary amine (-NH2) groups.
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00138

Axiom
annotated source: carboxyl
annotated property: definition
annotated target: A reactive group (-COOH) that reacts with primary amine (-NH2) groups.
database_cross_reference: PSI:XL

hydroxymethyl phosphine
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A reactive group that reacts with amine groups.
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00139

Axiom
annotated source: hydroxymethyl phosphine
annotated property: definition
annotated target: A reactive group that reacts with amine groups.
database_cross_reference: PSI:XL

vinyl sulfone
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
definition: A reactive group that reacts with hydroxyl groups.
specificities: (C,K,N,Q,R,S,T,Y)
has_obo_namespace: XLMOD
id: XLMOD:00140

Axiom
annotated source: vinyl sulfone
annotated property: definition
annotated target: A reactive group that reacts with hydroxyl groups.
database_cross_reference: PSI:XL

carbonyl
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydrazine reactive
definition: A reactive group (C=O)that reacts with hydrazines (N2H4).
has_obo_namespace: XLMOD
id: XLMOD:00141

Axiom
annotated source: carbonyl
annotated property: definition
annotated target: A reactive group (C=O)that reacts with hydrazines (N2H4).
database_cross_reference: PSI:XL

phenylglyoxal
type: Class
subclass of: glyoxal
definition: An arginine-specific reactive group.
specificities: (R)
has_obo_namespace: XLMOD
id: XLMOD:00142

Axiom
annotated source: phenylglyoxal
annotated property: definition
annotated target: An arginine-specific reactive group.
database_cross_reference: PSI:XL

hydrazone
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
definition: A hydrazone reactive group (C=NH-NHR) that reacts with carbonyls.
specificities: (D,E,Protein C-term)
has_obo_namespace: XLMOD
id: XLMOD:00143

Axiom
annotated source: hydrazone
annotated property: definition
annotated target: A hydrazone reactive group (C=NH-NHR) that reacts with carbonyls.
database_cross_reference: PSI:XL

S-acetyl
type: Class
subclass of: reactive group
definition: A S-acetyl group.
has_exact_synonym: SAT
has_obo_namespace: XLMOD
id: XLMOD:00144
comment: Used to incorporate sulfhydryl (-SH) groups into proteins as part of a two-step or heterobifunctional crosslinking strategy.

Axiom
annotated source: S-acetyl
annotated property: definition
annotated target: A S-acetyl group.
database_cross_reference: PSI:XL

aryl halide
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: An aryl halide group (Ar-halogen) that reacts with primary amines.
specificities: (K,N,Q,R,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00145

Axiom
annotated source: aryl halide
annotated property: definition
annotated target: An aryl halide group (Ar-halogen) that reacts with primary amines.
database_cross_reference: PSI:XL

dimethylether
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: A dimethylether (Ch3-O-CH3) reactive group that reacts with carboxyl groups.
specificities: (D,E)
has_obo_namespace: XLMOD
id: XLMOD:00146

Axiom
annotated source: dimethylether
annotated property: definition
annotated target: A dimethylether (Ch3-O-CH3) reactive group that reacts with carboxyl groups.
database_cross_reference: PSI:XL

photocleavable
type: Class
subclass of: photoreactive
definition: Indicates that a reactive group is photocleavable.
has_obo_namespace: XLMOD
id: XLMOD:00147

Axiom
annotated source: photocleavable
annotated property: definition
annotated target: Indicates that a reactive group is photocleavable.
database_cross_reference: PSI:XL

nitrobenzylester
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_cleavable
  some values from: photocleavable
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: A photocleavable group.
has_obo_namespace: XLMOD
id: XLMOD:00148

Axiom
annotated source: nitrobenzylester
annotated property: definition
annotated target: A photocleavable group.
database_cross_reference: PSI:XL

photoactivatable
type: Class
subclass of: photoreactive
definition: Indicates that a reactive group is photoactivatable.
has_obo_namespace: XLMOD
id: XLMOD:00149

Axiom
annotated source: photoactivatable
annotated property: definition
annotated target: Indicates that a reactive group is photoactivatable.
database_cross_reference: PSI:XL

tetrafluorophenyl ester
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Tetrafluorophenyl (TFP, F4-Ph) ester.
has_obo_namespace: XLMOD
id: XLMOD:00150

Axiom
annotated source: tetrafluorophenyl ester
annotated property: definition
annotated target: Tetrafluorophenyl (TFP, F4-Ph) ester.
database_cross_reference: PMID:22641729

pentylamine
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: A pentylamine (CH3(CH2)4-NH2) reactive group that reacts with carboxyl groups.
specificities: (D,E)
has_obo_namespace: XLMOD
id: XLMOD:00151

Axiom
annotated source: pentylamine
annotated property: definition
annotated target: A pentylamine (CH3(CH2)4-NH2) reactive group that reacts with carboxyl groups.
database_cross_reference: PSI:XL

Biotin
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: avidin reactive
definition: A biotin reactive group that reacts with avidin, streptavidin or neutravidin.
has_obo_namespace: XLMOD
id: XLMOD:00152

Axiom
annotated source: Biotin
annotated property: definition
annotated target: A biotin reactive group that reacts with avidin, streptavidin or neutravidin.
database_cross_reference: PSI:XL

chloroethyl
type: Class
subclass of: reactive group
definition: A reactive group that reacts with guanin.
base specificities: (Guanine)
secondary base specificities: (Adenine, Cytosine)
has_obo_namespace: XLMOD
id: XLMOD:00153

Axiom
annotated source: chloroethyl
annotated property: definition
annotated target: A reactive group that reacts with guanin.
database_cross_reference: PSI:XL

imino
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: An imino (R1R2-C=N-R3) reactive group that reacts with primary amines.
specificities: (D,E,K,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:00154

Axiom
annotated source: imino
annotated property: definition
annotated target: An imino (R1R2-C=N-R3) reactive group that reacts with primary amines.
database_cross_reference: PSI:XL

acyl chloride
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: An acyl chloride (R-CO-Cl) reactive group that reacts with alcohol, phenol, thiol and amines.
has_obo_namespace: XLMOD
id: XLMOD:00155

Axiom
annotated source: acyl chloride
annotated property: definition
annotated target: An acyl chloride (R-CO-Cl) reactive group that reacts with alcohol, phenol, thiol and amines.
database_cross_reference: PMID:21557289

sulfonyl chloride
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: A sulfonyl chloride (R-SO2-Cl) reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00156

Axiom
annotated source: sulfonyl chloride
annotated property: definition
annotated target: A sulfonyl chloride (R-SO2-Cl) reactive group.
database_cross_reference: PMID:21557289

benzofurazan
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: A benzofurazan (2,1,3-benzoxadiazole) reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00157

Axiom
annotated source: benzofurazan
annotated property: definition
annotated target: A benzofurazan (2,1,3-benzoxadiazole) reactive group.
database_cross_reference: PMID:21557289

halobenzofurazan
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: A halobenzofurazan (2,1,3-benzoxadiazole) reactive group with a halogen (-F, -Cl) modification.
has_obo_namespace: XLMOD
id: XLMOD:00158

Axiom
annotated source: halobenzofurazan
annotated property: definition
annotated target: A halobenzofurazan (2,1,3-benzoxadiazole) reactive group with a halogen (-F, -Cl) modification.
database_cross_reference: PMID:21557289

hydrazine
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: A hydrazine (R-NHNH2-) reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00159

Axiom
annotated source: hydrazine
annotated property: definition
annotated target: A hydrazine (R-NHNH2-) reactive group.
database_cross_reference: PMID:21557289

TAD
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: Vitamin D metabolite reactive
definition: A 4-substituted 1,2,4-triazoline-3,5-dione (TAD) reactive group.
has_exact_synonym: 1,2,4-triazoline-3,5-dione
has_obo_namespace: XLMOD
id: XLMOD:00160

Axiom
annotated source: TAD
annotated property: definition
annotated target: A 4-substituted 1,2,4-triazoline-3,5-dione (TAD) reactive group.
database_cross_reference: PMID:21557289

boronic acid
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbohydrate reactive
definition: An (alkyl- or aryl-substituted) boronic acid (R-B-(OH)2) reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00161

Axiom
annotated source: boronic acid
annotated property: definition
annotated target: An (alkyl- or aryl-substituted) boronic acid (R-B-(OH)2) reactive group.
database_cross_reference: PMID:21557289

isothiocyanate
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
definition: An isothiocyanate (-N=C=S) reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00162

Axiom
annotated source: isothiocyanate
annotated property: definition
annotated target: An isothiocyanate (-N=C=S) reactive group.
database_cross_reference: PMID:21557289

chloroformate reactive group
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
definition: A chloroformate (Cl-CO-OR) reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00163

Axiom
annotated source: chloroformate reactive group
annotated property: definition
annotated target: A chloroformate (Cl-CO-OR) reactive group.
database_cross_reference: PMID:21557289

carabamate
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
definition: A carbamate (O-CO-N) reactive group.
has_exact_synonym: urethane
has_obo_namespace: XLMOD
id: XLMOD:00164

Axiom
annotated source: carabamate
annotated property: definition
annotated target: A carbamate (O-CO-N) reactive group.
database_cross_reference: PMID:21557289

sulfonate
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: A sulfonate (R1-SO2O-R2) reactive group.
has_exact_synonym: sulfonic ester
has_exact_synonym: sulphonate
has_obo_namespace: XLMOD
id: XLMOD:00165

Axiom
annotated source: sulfonate
annotated property: definition
annotated target: A sulfonate (R1-SO2O-R2) reactive group.
database_cross_reference: PMID:21557289

anhydride
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
definition: An anhydride (R1-CO-O-CO-R2) reactive group.
has_obo_namespace: XLMOD
id: XLMOD:00166

Axiom
annotated source: anhydride
annotated property: definition
annotated target: An anhydride (R1-CO-O-CO-R2) reactive group.
database_cross_reference: PMID:21557289

carboxyl reactive group
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Reactive group (-COOH) that reacts with amino (-NH2) groups.
has_obo_namespace: XLMOD
id: XLMOD:00167

Axiom
annotated source: carboxyl reactive group
annotated property: definition
annotated target: Reactive group (-COOH) that reacts with amino (-NH2) groups.
database_cross_reference: PSI:XL

benzyl bromide reactive group
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phophate reactive
definition: A benzyl bromide (C6H5CH2Br) reactive group.
has_exact_synonym: Bn-Br
has_obo_namespace: XLMOD
id: XLMOD:00168

Axiom
annotated source: benzyl bromide reactive group
annotated property: definition
annotated target: A benzyl bromide (C6H5CH2Br) reactive group.
database_cross_reference: PMID:21557289

sodium dithionite cleavable
type: Class
subclass of: chemically cleavable
definition: Indicates that a cross-linker is chemically cleavable by sodium dithionite.
has_obo_namespace: XLMOD
id: XLMOD:00169

Axiom
annotated source: sodium dithionite cleavable
annotated property: definition
annotated target: Indicates that a cross-linker is chemically cleavable by sodium dithionite.
database_cross_reference: PSI:XL

benzoyl bromide
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phophate reactive
definition: A benzoyl bromide (C6H5COBr) reactive group.
has_exact_synonym: Bz-Br
has_obo_namespace: XLMOD
id: XLMOD:00170

Axiom
annotated source: benzoyl bromide
annotated property: definition
annotated target: A benzoyl bromide (C6H5COBr) reactive group.
database_cross_reference: PMID:21557289

Ortho-phthalaldehyde
type: Class
subclass of: aldehyde group
definition: A lysine-specific reactive group.
specificities: (K)
has_exact_synonym: OPA
has_obo_namespace: XLMOD
id: XLMOD:00171

Axiom
annotated source: Ortho-phthalaldehyde
annotated property: definition
annotated target: A lysine-specific reactive group.
database_cross_reference: PSI:XL

IMAC-enrichable
type: Class
subclass of: enrichable
definition: Indicates a cross-linker facilitating IMAC (immobilized metal affinity chromatography) enrichment.
has_obo_namespace: XLMOD
id: XLMOD:00172

Axiom
annotated source: IMAC-enrichable
annotated property: definition
annotated target: Indicates a cross-linker facilitating IMAC (immobilized metal affinity chromatography) enrichment.
database_cross_reference: PSI:XL

phosphonic acid
type: Class
subclass of: handle
subclass of: IMAC-enrichable
definition: A phosphonic acid handle, which can be used for IMAC-enrichment.
has_obo_namespace: XLMOD
id: XLMOD:00173

Axiom
annotated source: phosphonic acid
annotated property: definition
annotated target: A phosphonic acid handle, which can be used for IMAC-enrichment.
database_cross_reference: PSI:XL

hydrolyzed BS3
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS3
definition: Hydrolyzed bis(sulfosuccinimidyl)suberate.
dead end formula: C8 H12 O3
mono isotopic mass: 156.07864431
has_obo_namespace: XLMOD
id: XLMOD:01000

Axiom
annotated source: hydrolyzed BS3
annotated property: definition
annotated target: Hydrolyzed bis(sulfosuccinimidyl)suberate.
database_cross_reference: PSI:XL

ammonium amidated BS3
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS3
definition: Ammonium amidated bis(sulfosuccinimidyl)suberate.
dead end formula: C8 H13 O2 N
mono isotopic mass: 155.094628715
has_obo_namespace: XLMOD
id: XLMOD:01001

Axiom
annotated source: ammonium amidated BS3
annotated property: definition
annotated target: Ammonium amidated bis(sulfosuccinimidyl)suberate.
database_cross_reference: PSI:XL

hydrolyzed DSS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSS
definition: Hydrolyzed disuccinimidyl suberate.
dead end formula: C8 H12 O3
mono isotopic mass: 156.07864431
has_obo_namespace: XLMOD
id: XLMOD:01002

Axiom
annotated source: hydrolyzed DSS
annotated property: definition
annotated target: Hydrolyzed disuccinimidyl suberate.
database_cross_reference: PSI:XL

ammonium amidated DSS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSS
definition: Ammonium amidated disuccinimidyl suberate.
dead end formula: C8 H13 O2 N
mono isotopic mass: 155.094628715
has_obo_namespace: XLMOD
id: XLMOD:01003

Axiom
annotated source: ammonium amidated DSS
annotated property: definition
annotated target: Ammonium amidated disuccinimidyl suberate.
database_cross_reference: PSI:XL

hydrolyzed DSS-d4
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSS-d4
definition: Deuterium labelled hydrolyzed disuccinimidyl 2,2,7,7-suberate.
mono isotopic mass: 160.1037416836
has_obo_namespace: XLMOD
id: XLMOD:01004

Axiom
annotated source: hydrolyzed DSS-d4
annotated property: definition
annotated target: Deuterium labelled hydrolyzed disuccinimidyl 2,2,7,7-suberate.
database_cross_reference: PSI:XL

ammonium amidated DSS-d4
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSS-d4
definition: Deuterium labelled ammonium amidated disuccinimidyl 2,2,7,7-suberate.
mono isotopic mass: 159.1197260886
has_obo_namespace: XLMOD
id: XLMOD:01005

Axiom
annotated source: ammonium amidated DSS-d4
annotated property: definition
annotated target: Deuterium labelled ammonium amidated disuccinimidyl 2,2,7,7-suberate.
database_cross_reference: PSI:XL

hydrolyzed DSS-d12
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSS-d12
definition: Deuterium labelled hydrolyzed disuccinimidyl 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
mono isotopic mass: 168.153965238
has_obo_namespace: XLMOD
id: XLMOD:01006

Axiom
annotated source: hydrolyzed DSS-d12
annotated property: definition
annotated target: Deuterium labelled hydrolyzed disuccinimidyl 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
database_cross_reference: PSI:XL

ammonium amidated DSS-d12
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSS-d12
definition: Deuterium labelled ammonium amidated disuccinimidyl 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
mono isotopic mass: 167.169949643
has_obo_namespace: XLMOD
id: XLMOD:01007

Axiom
annotated source: ammonium amidated DSS-d12
annotated property: definition
annotated target: Deuterium labelled ammonium amidated disuccinimidyl 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
database_cross_reference: PSI:XL

hydrolyzed BS3-d4
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS3-d4
definition: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,7,7-suberate.
dead end formula: C8 D4 H8 O3
mono isotopic mass: 160.103751286
has_obo_namespace: XLMOD
id: XLMOD:01008

Axiom
annotated source: hydrolyzed BS3-d4
annotated property: definition
annotated target: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,7,7-suberate.
database_cross_reference: PSI:XL

ammonium amidated BS3-d4
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS3-d4
definition: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,7,7-suberate.
dead end formula: C8 D4 H9 N1 O2
mono isotopic mass: 159.119735691
has_obo_namespace: XLMOD
id: XLMOD:01009

Axiom
annotated source: ammonium amidated BS3-d4
annotated property: definition
annotated target: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,7,7-suberate.
database_cross_reference: PSI:XL

hydrolyzed BS2G
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS2G
definition: Hydrolyzed bis(sulfosuccinimidyl) glutarate.
dead end formula: C5 H6 O3
mono isotopic mass: 114.0316941
has_obo_namespace: XLMOD
id: XLMOD:01010

Axiom
annotated source: hydrolyzed BS2G
annotated property: definition
annotated target: Hydrolyzed bis(sulfosuccinimidyl) glutarate.
database_cross_reference: PSI:XL

ammonium amidated BS2G
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS2G
definition: Ammonium amidated bis(sulfosuccinimidyl) glutarate.
dead end formula: C5 H7 N1 O2
mono isotopic mass: 113.047678505
has_obo_namespace: XLMOD
id: XLMOD:01011

Axiom
annotated source: ammonium amidated BS2G
annotated property: definition
annotated target: Ammonium amidated bis(sulfosuccinimidyl) glutarate.
database_cross_reference: PSI:XL

hydrolyzed DSG
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSG
definition: Hydrolyzed disuccinimidyl glutarate.
dead end formula: C5 H6 O3
mono isotopic mass: 114.0316941
has_obo_namespace: XLMOD
id: XLMOD:01012

Axiom
annotated source: hydrolyzed DSG
annotated property: definition
annotated target: Hydrolyzed disuccinimidyl glutarate.
database_cross_reference: PSI:XL

ammonium amidated DSG
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSG
definition: Ammonium amidated disuccinimidyl glutarate.
dead end formula: C5 H7 N1 O2
mono isotopic mass: 113.047678505
has_obo_namespace: XLMOD
id: XLMOD:01013

Axiom
annotated source: ammonium amidated DSG
annotated property: definition
annotated target: Ammonium amidated disuccinimidyl glutarate.
database_cross_reference: PSI:XL

hydrolyzed DSG-d4
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSG-d4
definition: Deuterium labelled hydrolyzed disuccinimidyl 2,2,4,4-glutarate.
dead end formula: C5 D4 H2 O3
mono isotopic mass: 118.0567741
has_obo_namespace: XLMOD
id: XLMOD:01014

Axiom
annotated source: hydrolyzed DSG-d4
annotated property: definition
annotated target: Deuterium labelled hydrolyzed disuccinimidyl 2,2,4,4-glutarate.
database_cross_reference: PSI:XL

ammonium amidated DSG-d4
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSG-d4
definition: Deuterium labelled ammonium amidated disuccinimidyl 2,2,4,4-glutarate.
dead end formula: C5 D4 H3 N1 O2
mono isotopic mass: 117.072758505
has_obo_namespace: XLMOD
id: XLMOD:01015

Axiom
annotated source: ammonium amidated DSG-d4
annotated property: definition
annotated target: Deuterium labelled ammonium amidated disuccinimidyl 2,2,4,4-glutarate.
database_cross_reference: PSI:XL

hydrolyzed BS2G-d4
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS2G-d4
definition: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,4,4-glutarate.
dead end formula: C5 D4 H2 O3
mono isotopic mass: 118.056801076
has_obo_namespace: XLMOD
id: XLMOD:01016

Axiom
annotated source: hydrolyzed BS2G-d4
annotated property: definition
annotated target: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,4,4-glutarate.
database_cross_reference: PSI:XL

ammonium amidated BS2G-d4
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS2G-d4
definition: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,4,4-glutarate.
dead end formula: C5 D4 H3 N1 O2
mono isotopic mass: 117.072785481
has_obo_namespace: XLMOD
id: XLMOD:01017

Axiom
annotated source: ammonium amidated BS2G-d4
annotated property: definition
annotated target: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,4,4-glutarate.
database_cross_reference: PSI:XL

BDP-NHP-stump
type: Class
subclass of: cross-linker related chemical modification
subclass of: Restriction
  on property: is_side_product_of
  some values from: BDP-NHP
definition: Biotin Aspartate Proline n-hydroxyphthalimide-stump.
mono isotopic mass: 197.032422395
has_obo_namespace: XLMOD
id: XLMOD:01018

Axiom
annotated source: BDP-NHP-stump
annotated property: definition
annotated target: Biotin Aspartate Proline n-hydroxyphthalimide-stump.
database_cross_reference: PMID:23413883
database_cross_reference: PMID:26235782
database_cross_reference: PMID:27089058

hydrolyzed DSP
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSP
definition: Hydrolyzed dithiobis[succinimidyl propionate.
dead end formula: C6 H8 O3 S2
mono isotopic mass: 191.99148557
has_obo_namespace: XLMOD
id: XLMOD:01019

Axiom
annotated source: hydrolyzed DSP
annotated property: definition
annotated target: Hydrolyzed dithiobis[succinimidyl propionate.
database_cross_reference: PSI:XL

ammonium amidated DSP
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSP
definition: Ammonium amidated dithiobis[succinimidyl propionate.
dead end formula: C6 H9 N1 O2 S2
mono isotopic mass: 191.007469975
has_obo_namespace: XLMOD
id: XLMOD:01020

Axiom
annotated source: ammonium amidated DSP
annotated property: definition
annotated target: Ammonium amidated dithiobis[succinimidyl propionate.
database_cross_reference: PSI:XL

hydrolyzed EGS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: EGS
definition: Hydrolyzed ethylene glycolbis(succinimidylsuccinate).
dead end formula: C10 H12 O7
mono isotopic mass: 244.0583027
has_obo_namespace: XLMOD
id: XLMOD:01021

Axiom
annotated source: hydrolyzed EGS
annotated property: definition
annotated target: Hydrolyzed ethylene glycolbis(succinimidylsuccinate).
database_cross_reference: PSI:XL

ammonium amidated EGS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: EGS
definition: Ammonium amidated ethylene glycolbis(succinimidylsuccinate).
dead end formula: C10 H13 N1 O6
mono isotopic mass: 243.074287105
has_obo_namespace: XLMOD
id: XLMOD:01022

Axiom
annotated source: ammonium amidated EGS
annotated property: definition
annotated target: Ammonium amidated ethylene glycolbis(succinimidylsuccinate).
database_cross_reference: PSI:XL

hydrolyzed BiPS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BiPS
definition: Hydrolyzed bimane bisthiopropionic acid N-succinimidyl ester.
dead end formula: C16 H18 N2 O5 S2
mono isotopic mass: 382.06571
has_obo_namespace: XLMOD
id: XLMOD:01023

Axiom
annotated source: hydrolyzed BiPS
annotated property: definition
annotated target: Hydrolyzed bimane bisthiopropionic acid N-succinimidyl ester.
database_cross_reference: PMID:18838738

ammonium amidated BiPS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BiPS
definition: Ammonium amidated bimane bisthiopropionic acid N-succinimidyl ester.
dead end formula: C16 H18 N3 O4 S2
mono isotopic mass: 381.08169
has_obo_namespace: XLMOD
id: XLMOD:01024

Axiom
annotated source: ammonium amidated BiPS
annotated property: definition
annotated target: Ammonium amidated bimane bisthiopropionic acid N-succinimidyl ester.
database_cross_reference: PMID:18838738

hydrolyzed CBDPS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: formaldehyde
definition: Hydrolyzed cyanurbiotindipropionylsuccinimide.
dead end formula: C19 H25 N7 O5 S3
mono isotopic mass: 527.10738
has_obo_namespace: XLMOD
id: XLMOD:01025

Axiom
annotated source: hydrolyzed CBDPS
annotated property: definition
annotated target: Hydrolyzed cyanurbiotindipropionylsuccinimide.
database_cross_reference: PMID:20622150

ammonium amidated CBDPS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: formaldehyde
definition: Ammonium amidated cyanurbiotindipropionylsuccinimide.
dead end formula: C19 H25 N8 O4 S3
mono isotopic mass: 526.12336
has_obo_namespace: XLMOD
id: XLMOD:01026

Axiom
annotated source: ammonium amidated CBDPS
annotated property: definition
annotated target: Ammonium amidated cyanurbiotindipropionylsuccinimide.
database_cross_reference: PMID:20622150

hydrolyzed DSA
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DNBDPS
definition: Hydrolyzed disuccinimidyladipic acid.
dead end formula: C6 H8 O3
mono isotopic mass: 128.0468
has_obo_namespace: XLMOD
id: XLMOD:01027

Axiom
annotated source: hydrolyzed DSA
annotated property: definition
annotated target: Hydrolyzed disuccinimidyladipic acid.
database_cross_reference: PSI:XL

ammonium amidated DSA
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DNBDPS
definition: Ammonium amidated disuccinimidyladipic acid.
dead end formula: C6 H9 N1 O2
mono isotopic mass: 127.06278
has_obo_namespace: XLMOD
id: XLMOD:01028

Axiom
annotated source: ammonium amidated DSA
annotated property: definition
annotated target: Ammonium amidated disuccinimidyladipic acid.
database_cross_reference: PSI:XL

hydrolyzed DNBDPS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: DNB
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: TEABS
definition: Hydrolyzed DNBDPS.
dead end formula: C12 H10 N2 O7 S2
mono isotopic mass: 357.99294
has_obo_namespace: XLMOD
id: XLMOD:01029

Axiom
annotated source: hydrolyzed DNBDPS
annotated property: definition
annotated target: Hydrolyzed DNBDPS.
database_cross_reference: PMID:20109223

ammonium amidated DNBDPS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: DNB
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: TEABS
definition: Ammonium amidated DNBDPS.
dead end formula: C12 H10 N3 O6 S2
mono isotopic mass: 357.00892
has_obo_namespace: XLMOD
id: XLMOD:01030

Axiom
annotated source: ammonium amidated DNBDPS
annotated property: definition
annotated target: Ammonium amidated DNBDPS.
database_cross_reference: PMID:20109223

hydrolyzed TEABS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: CLIP
definition: Hydrolyzed TEABS cross-linking reagent.
dead end formula: C28 H41 N5 O12 S1
mono isotopic mass: 671.24724
has_obo_namespace: XLMOD
id: XLMOD:01031

Axiom
annotated source: hydrolyzed TEABS
annotated property: definition
annotated target: Hydrolyzed TEABS cross-linking reagent.
database_cross_reference: PMID:20109223

ammonium amidated TEABS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: CLIP
definition: Ammonium amidated TEABS cross-linking reagent.
dead end formula: C28 H41 N6 O11 S1
mono isotopic mass: 670.26322
has_obo_namespace: XLMOD
id: XLMOD:01032

Axiom
annotated source: ammonium amidated TEABS
annotated property: definition
annotated target: Ammonium amidated TEABS cross-linking reagent.
database_cross_reference: PMID:20109223

hydrolyzed DTSSP-d8
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: EGS-d12
definition: Hydrolyzed deuterium labelled 3,3'-Dithiobis[sulfosuccinimidylpropionate].
dead end formula: C6 D8 O3 S2
mono isotopic mass: 191.99149
has_obo_namespace: XLMOD
id: XLMOD:01033

Axiom
annotated source: hydrolyzed DTSSP-d8
annotated property: definition
annotated target: Hydrolyzed deuterium labelled 3,3'-Dithiobis[sulfosuccinimidylpropionate].
database_cross_reference: PMID:10975572
database_cross_reference: PMID:18510349

ammonium amidated DTSSP-d8
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: EGS-d12
definition: Ammonium amidated deuterium labelled 3,3'-Dithiobis[sulfosuccinimidylpropionate].
dead end formula: C6 D8 H1 N1 O2 S2
mono isotopic mass: 191.00747
has_obo_namespace: XLMOD
id: XLMOD:01034

Axiom
annotated source: ammonium amidated DTSSP-d8
annotated property: definition
annotated target: Ammonium amidated deuterium labelled 3,3'-Dithiobis[sulfosuccinimidylpropionate].
database_cross_reference: PMID:10975572
database_cross_reference: PMID:18510349

hydrolyzed DSP-d8
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSP-d8
definition: Hydrolyzed deuterium-labelled dithiobis[succinimidyl propionate.
dead end formula: C6 D8 O3 S2
mono isotopic mass: 200.04165
has_obo_namespace: XLMOD
id: XLMOD:01035

Axiom
annotated source: hydrolyzed DSP-d8
annotated property: definition
annotated target: Hydrolyzed deuterium-labelled dithiobis[succinimidyl propionate.
database_cross_reference: PSI:XL

ammonium amidated DSP-d8
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSP-d8
definition: Ammonium amidated deuterium-labelled dithiobis[succinimidyl propionate.
dead end formula: C6 D8 H1 N1 O2 S2
mono isotopic mass: 199.05763
has_obo_namespace: XLMOD
id: XLMOD:01036

Axiom
annotated source: ammonium amidated DSP-d8
annotated property: definition
annotated target: Ammonium amidated deuterium-labelled dithiobis[succinimidyl propionate.
database_cross_reference: PSI:XL

hydrolyzed Sulfo-EGS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: Sulfo-EGS
definition: Hydrolyzed ethylene glycolbis(sulfosuccinimidylsuccinate).
dead end formula: C10 H12 O7
mono isotopic mass: 244.0583028
has_obo_namespace: XLMOD
id: XLMOD:01037

Axiom
annotated source: hydrolyzed Sulfo-EGS
annotated property: definition
annotated target: Hydrolyzed ethylene glycolbis(sulfosuccinimidylsuccinate).
database_cross_reference: PSI:XL

ammonium amidated Sulfo-EGS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: Sulfo-EGS
definition: Ammonium amidated ethylene glycolbis(sulfosuccinimidylsuccinate).
dead end formula: C10 H12 N1 O6
mono isotopic mass: 243.07428
has_obo_namespace: XLMOD
id: XLMOD:01038

Axiom
annotated source: ammonium amidated Sulfo-EGS
annotated property: definition
annotated target: Ammonium amidated ethylene glycolbis(sulfosuccinimidylsuccinate).
database_cross_reference: PSI:XL

hydrolyzed EGS-d12
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: Sulfo-EGS-d12
definition: Deuterium labelled hydrolyzed ethylene glycolbis(succinimidylsuccinate).
dead end formula: C10 D12 O7
mono isotopic mass: 256.13403
has_obo_namespace: XLMOD
id: XLMOD:01039

Axiom
annotated source: hydrolyzed EGS-d12
annotated property: definition
annotated target: Deuterium labelled hydrolyzed ethylene glycolbis(succinimidylsuccinate).
database_cross_reference: PSI:XL

ammonium amidated EGS-d12
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: Sulfo-EGS-d12
definition: Deuterium labelled ammonium amidated ethylene glycolbis(succinimidylsuccinate).
dead end formula: C10 D12 N1 O6
mono isotopic mass: 255.15001
has_obo_namespace: XLMOD
id: XLMOD:01040

Axiom
annotated source: ammonium amidated EGS-d12
annotated property: definition
annotated target: Deuterium labelled ammonium amidated ethylene glycolbis(succinimidylsuccinate).
database_cross_reference: PSI:XL

hydrolyzed Sulfo-EGS-d12
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: Sulfo-EGS-d12
definition: Deuterium labelled hydrolyzed ethylene glycolbis(sulfosuccinimidylsuccinate).
dead end formula: C10 D12 O7
mono isotopic mass: 256.13403
has_obo_namespace: XLMOD
id: XLMOD:01041

Axiom
annotated source: hydrolyzed Sulfo-EGS-d12
annotated property: definition
annotated target: Deuterium labelled hydrolyzed ethylene glycolbis(sulfosuccinimidylsuccinate).
database_cross_reference: PSI:XL

ammonium amidated Sulfo-EGS-d12
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: Sulfo-EGS-d12
definition: Deuterium labelled ammonium amidated ethylene glycolbis(sulfosuccinimidylsuccinate).
dead end formula: C10 D12 N1 O6
mono isotopic mass: 255.15001
has_obo_namespace: XLMOD
id: XLMOD:01042

Axiom
annotated source: ammonium amidated Sulfo-EGS-d12
annotated property: definition
annotated target: Deuterium labelled ammonium amidated ethylene glycolbis(sulfosuccinimidylsuccinate).
database_cross_reference: PSI:XL

hydrolyzed DSA-13C6
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: CBDPS-d8
definition: Hydrolyzed 13C labelled disuccinimidyladipic acid.
dead end formula: 13C6 H8 O3
mono isotopic mass: 134.06696
has_obo_namespace: XLMOD
id: XLMOD:01043

Axiom
annotated source: hydrolyzed DSA-13C6
annotated property: definition
annotated target: Hydrolyzed 13C labelled disuccinimidyladipic acid.
database_cross_reference: PSI:XL

ammonium amidated DSA-13C6
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: CBDPS-d8
definition: Ammonium amidated 13C labelled disuccinimidyladipic acid.
dead end formula: 13C6 H9 N1 O2
mono isotopic mass: 133.08294
has_obo_namespace: XLMOD
id: XLMOD:01044

Axiom
annotated source: ammonium amidated DSA-13C6
annotated property: definition
annotated target: Ammonium amidated 13C labelled disuccinimidyladipic acid.
database_cross_reference: PSI:XL

hydrolyzed CBDPS-d8
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: CBDPSS
definition: Deuterium labelled hydrolyzed cyanurbiotindipropionylsuccinimide.
dead end formula: C19 D8 H17 N7 O5 S3
mono isotopic mass: 535.15754
has_obo_namespace: XLMOD
id: XLMOD:01045

Axiom
annotated source: hydrolyzed CBDPS-d8
annotated property: definition
annotated target: Deuterium labelled hydrolyzed cyanurbiotindipropionylsuccinimide.
database_cross_reference: PMID:20622150

ammonium amidated CBDPS-d8
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: CBDPSS
definition: Deuterium labelled ammonium amidated cyanurbiotindipropionylsuccinimide.
dead end formula: C19 D8 H17 N8 O4 S3
mono isotopic mass: 534.17352
has_obo_namespace: XLMOD
id: XLMOD:01046

Axiom
annotated source: ammonium amidated CBDPS-d8
annotated property: definition
annotated target: Deuterium labelled ammonium amidated cyanurbiotindipropionylsuccinimide.
database_cross_reference: PMID:20622150

hydrolyzed CBDPSS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: CBDPSS-d8
definition: Hydrolyzed cyanurbiotindimercaptopropionylsulfosuccinimide.
dead end formula: C19 H25 N7 O5 S3
mono isotopic mass: 527.10738
has_obo_namespace: XLMOD
id: XLMOD:01047

Axiom
annotated source: hydrolyzed CBDPSS
annotated property: definition
annotated target: Hydrolyzed cyanurbiotindimercaptopropionylsulfosuccinimide.
database_cross_reference: PMID:20622150

ammonium amidated CBDPSS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: CBDPSS-d8
definition: Ammonium amidated cyanurbiotindimercaptopropionylsulfosuccinimide.
dead end formula: C19 H25 N8 O4 S3
mono isotopic mass: 526.12336
has_obo_namespace: XLMOD
id: XLMOD:01048

Axiom
annotated source: ammonium amidated CBDPSS
annotated property: definition
annotated target: Ammonium amidated cyanurbiotindimercaptopropionylsulfosuccinimide.
database_cross_reference: PMID:20622150

hydrolyzed CBDPSS-d8
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: SDH
definition: Deuterium labelled hydrolyzed cyanurbiotindimercaptopropionylsulfosuccinimide.
dead end formula: C19 D8 H17 N7 O5 S3
mono isotopic mass: 535.15754
has_obo_namespace: XLMOD
id: XLMOD:01049

Axiom
annotated source: hydrolyzed CBDPSS-d8
annotated property: definition
annotated target: Deuterium labelled hydrolyzed cyanurbiotindimercaptopropionylsulfosuccinimide.
database_cross_reference: PMID:20622150

ammonium amidated CBDPSS-d8
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: SDH
definition: Deuterium labelled ammonium amidated cyanurbiotindimercaptopropionylsulfosuccinimide.
dead end formula: C19 D8 H17 N8 O4 S3
mono isotopic mass: 534.17352
has_obo_namespace: XLMOD
id: XLMOD:01050

Axiom
annotated source: ammonium amidated CBDPSS-d8
annotated property: definition
annotated target: Deuterium labelled ammonium amidated cyanurbiotindimercaptopropionylsulfosuccinimide.
database_cross_reference: PMID:20622150

hydrolyzed BS3-d12
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSG-d6
definition: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
dead end formula: C8 D12 O3
mono isotopic mass: 168.15437
has_obo_namespace: XLMOD
id: XLMOD:01051

Axiom
annotated source: hydrolyzed BS3-d12
annotated property: definition
annotated target: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
database_cross_reference: PSI:XL

ammonium amidated BS3-d12
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DSG-d6
definition: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
dead end formula: C8 D12 H1 N1 O2
mono isotopic mass: 167.17035
has_obo_namespace: XLMOD
id: XLMOD:01052

Axiom
annotated source: ammonium amidated BS3-d12
annotated property: definition
annotated target: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
database_cross_reference: PSI:XL

hydrolyzed DSG-d6
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS2G-d6
definition: Deuterium labelled hydrolyzed disuccinimidyl 2,2,3,3,4,4-glutarate.
dead end formula: C5 D6 O3
mono isotopic mass: 120.07483
has_obo_namespace: XLMOD
id: XLMOD:01053

Axiom
annotated source: hydrolyzed DSG-d6
annotated property: definition
annotated target: Deuterium labelled hydrolyzed disuccinimidyl 2,2,3,3,4,4-glutarate.
database_cross_reference: PSI:XL

ammonium amidated DSG-d6
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS2G-d6
definition: Deuterium labelled ammonium amidated disuccinimidyl 2,2,3,3,4,4-glutarate.
dead end formula: C5 D6 H1 N1 O2
mono isotopic mass: 119.09081
has_obo_namespace: XLMOD
id: XLMOD:01054

Axiom
annotated source: ammonium amidated DSG-d6
annotated property: definition
annotated target: Deuterium labelled ammonium amidated disuccinimidyl 2,2,3,3,4,4-glutarate.
database_cross_reference: PSI:XL

hydrolyzed BS2G-d6
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: SATA
definition: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,3,3,4,4-glutarate.
dead end formula: C5 D6 O3
mono isotopic mass: 120.06877
has_obo_namespace: XLMOD
id: XLMOD:01055

Axiom
annotated source: hydrolyzed BS2G-d6
annotated property: definition
annotated target: Deuterium labelled hydrolyzed bis(sulfosuccinimidyl) 2,2,3,3,4,4-glutarate.
database_cross_reference: PSI:XL

ammonium amidated BS2G-d6
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: SATA
definition: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,3,3,4,4-glutarate.
dead end formula: C5 D6 H1 N1 O2
mono isotopic mass: 119.08475
has_obo_namespace: XLMOD
id: XLMOD:01056

Axiom
annotated source: ammonium amidated BS2G-d6
annotated property: definition
annotated target: Deuterium labelled ammonium amidated bis(sulfosuccinimidyl) 2,2,3,3,4,4-glutarate.
database_cross_reference: PSI:XL

hydrolyzed SDH
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: SDH-d12
definition: Hydrolyzed Suberic acid 1,8-dihydrazide.
dead end formula: C8 H16 N4 O1
mono isotopic mass: 184.13241119
has_obo_namespace: XLMOD
id: XLMOD:01057

Axiom
annotated source: hydrolyzed SDH
annotated property: definition
annotated target: Hydrolyzed Suberic acid 1,8-dihydrazide.
database_cross_reference: PMID:24938783

hydrolyzed SDH-d12
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: ADH
definition: Deuterium labelled hydrolyzed suberic acid 1,8-dihydrazide.
dead end formula: C8 D12 H4 N4 O1
mono isotopic mass: 196.207732118
has_obo_namespace: XLMOD
id: XLMOD:01058

Axiom
annotated source: hydrolyzed SDH-d12
annotated property: definition
annotated target: Deuterium labelled hydrolyzed suberic acid 1,8-dihydrazide.
database_cross_reference: PMID:24938783

hydrolyzed ADH
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: ADH-d8
definition: Hydrolyzed adipic acid 1,6-dihydrazide.
dead end formula: C6 H12 N4 O1
mono isotopic mass: 156.10111105
has_obo_namespace: XLMOD
id: XLMOD:01059

Axiom
annotated source: hydrolyzed ADH
annotated property: definition
annotated target: Hydrolyzed adipic acid 1,6-dihydrazide.
database_cross_reference: PMID:24938783

hydrolyzed ADH-d8
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: ADH-d8
definition: Deuterium labelled hydrolyzed adipic acid 1,6-dihydrazide.
dead end formula: C6 D8 H4 N4 O1
mono isotopic mass: 164.151325002
has_obo_namespace: XLMOD
id: XLMOD:01060

Axiom
annotated source: hydrolyzed ADH-d8
annotated property: definition
annotated target: Deuterium labelled hydrolyzed adipic acid 1,6-dihydrazide.
database_cross_reference: PMID:24938783

hydrolyzed GDH
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: GDH-d6
definition: Hydrolyzed glutaric acid 1,5-dihydrazide.
dead end formula: C5 H10 N4 O1
mono isotopic mass: 142.08546098
has_obo_namespace: XLMOD
id: XLMOD:01061

Axiom
annotated source: hydrolyzed GDH
annotated property: definition
annotated target: Hydrolyzed glutaric acid 1,5-dihydrazide.
database_cross_reference: PMID:24938783

hydrolyzed GDH-d6
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS3-d12
definition: Deuterium labelled hydrolyzed glutaric acid 1,5-dihydrazide.
dead end formula: C5 D6 H4 N4 O1
mono isotopic mass: 148.123121444
has_obo_namespace: XLMOD
id: XLMOD:01062

Axiom
annotated source: hydrolyzed GDH-d6
annotated property: definition
annotated target: Deuterium labelled hydrolyzed glutaric acid 1,5-dihydrazide.
database_cross_reference: PMID:24938783

hydrolyzed BCCL1
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BCCL2
definition: Hydrolyzed bis-(N-hydroxysuccinimidyl) 3-amino-N-biotinoyl-1,5-pentanedioate.
mono isotopic mass: 355.12019
has_obo_namespace: XLMOD
id: XLMOD:01063

Axiom
annotated source: hydrolyzed BCCL1
annotated property: definition
annotated target: Hydrolyzed bis-(N-hydroxysuccinimidyl) 3-amino-N-biotinoyl-1,5-pentanedioate.
database_cross_reference: PMID:19412923

hydrolyzed BCCL2
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: SBC
definition: Hydrolyzed bis-(N-hydroxysuccinimidyl) 5-amino-N-biotinoyl-1,9-nonanedioate.
mono isotopic mass: 411.18179
has_obo_namespace: XLMOD
id: XLMOD:01064

Axiom
annotated source: hydrolyzed BCCL2
annotated property: definition
annotated target: Hydrolyzed bis-(N-hydroxysuccinimidyl) 5-amino-N-biotinoyl-1,9-nonanedioate.
database_cross_reference: PMID:19412923

hydrolyzed IRCX
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: azide-DSG
definition: Hydrolyzed dibenzoyloxysuccinimidylethyl phosphate.
mono isotopic mass: 348.0
has_obo_namespace: XLMOD
id: XLMOD:01065

Axiom
annotated source: hydrolyzed IRCX
annotated property: definition
annotated target: Hydrolyzed dibenzoyloxysuccinimidylethyl phosphate.
database_cross_reference: PMID:18517224

hydrolyzed azide-DSG
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: JMV 3378
definition: Hydrolyzed bis(succinimidyl)-3-azidomethyl glutarate.
mono isotopic mass: 229.0
has_obo_namespace: XLMOD
id: XLMOD:01066

Axiom
annotated source: hydrolyzed azide-DSG
annotated property: definition
annotated target: Hydrolyzed bis(succinimidyl)-3-azidomethyl glutarate.
database_cross_reference: PMID:20472459

hydrolyzed JMV 3378
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BuUrBu
definition: Hydrolyzed crosslinking reagent JMV 3378.
mono isotopic mass: 286.0
has_obo_namespace: XLMOD
id: XLMOD:01067

Axiom
annotated source: hydrolyzed JMV 3378
annotated property: definition
annotated target: Hydrolyzed crosslinking reagent JMV 3378.
database_cross_reference: PMID:19902427

hydrolyzed BuTuGPG
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DPS
definition: Hydrolyzed 4-[3-(2-{2-[(2,5-dioxo-pyrrolidin-1-yloxycarbonyl-methyl)-carbamoyl]-pyrrolidin-1-yl}-2-oxo-ethyl)-thioureido]-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester.
mono isotopic mass: 1704.86
has_obo_namespace: XLMOD
id: XLMOD:01068

Axiom
annotated source: hydrolyzed BuTuGPG
annotated property: definition
annotated target: Hydrolyzed 4-[3-(2-{2-[(2,5-dioxo-pyrrolidin-1-yloxycarbonyl-methyl)-carbamoyl]-pyrrolidin-1-yl}-2-oxo-ethyl)-thioureido]-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester.
database_cross_reference: PMID:19950134

hydrolyzed BuUrBu
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: SBBT
definition: Hydrolyzed NHS-amino butyric acid-urea-amino butyric acid-NHS.
has_obo_namespace: XLMOD
id: XLMOD:01069

Axiom
annotated source: hydrolyzed BuUrBu
annotated property: definition
annotated target: Hydrolyzed NHS-amino butyric acid-urea-amino butyric acid-NHS.
database_cross_reference: PMID:21157862

hydrolyzed DEST
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DC4
definition: Hydrolyzed diethylsuberthioimidate.
dead end formula: C8 H14 N2 O1
mono isotopic mass: 154.11061312
has_obo_namespace: XLMOD
id: XLMOD:01070

Axiom
annotated source: hydrolyzed DEST
annotated property: definition
annotated target: Hydrolyzed diethylsuberthioimidate.
database_cross_reference: PMID:20795639
database_cross_reference: PMID:22460622

ammonium amidated DEST
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DC4
definition: Ammonium amidated diethylsuberthioimidate.
dead end formula: C8 H15 N3
mono isotopic mass: 153.126593
has_obo_namespace: XLMOD
id: XLMOD:01071

Axiom
annotated source: ammonium amidated DEST
annotated property: definition
annotated target: Ammonium amidated diethylsuberthioimidate.
database_cross_reference: PMID:20795639
database_cross_reference: PMID:22460622

thioesterized DEST
type: Class
subclass of: thioesterization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: thioesterized
subclass of: Restriction
  on property: is_side_product_of
  some values from: DC4
definition: Thioesterized diethylsuberthioimidate.
dead end formula: C10 H17 N1 O1 S1
mono isotopic mass: 199.103084925
has_obo_namespace: XLMOD
id: XLMOD:01072

Axiom
annotated source: thioesterized DEST
annotated property: definition
annotated target: Thioesterized diethylsuberthioimidate.
database_cross_reference: PMID:20795639
database_cross_reference: PMID:22460622

hydrolyzed BS(PEG)5
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS(PEG)5
definition: Hydrolyzed bis(sulfosuccinimidyl)suberate pentaethyleneglycol.
dead end formula: C14 H24 O8
mono isotopic mass: 320.1471147
has_obo_namespace: XLMOD
id: XLMOD:01073

Axiom
annotated source: hydrolyzed BS(PEG)5
annotated property: definition
annotated target: Hydrolyzed bis(sulfosuccinimidyl)suberate pentaethyleneglycol.
database_cross_reference: PSI:XL

ammonium amidated BS(PEG)5
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BS(PEG)5
definition: Ammonium amidated bis(sulfosuccinimidyl)suberate pentaethyleneglycol.
dead end formula: C14 H27 N1 O7
mono isotopic mass: 320.1471147
has_obo_namespace: XLMOD
id: XLMOD:01074

Axiom
annotated source: ammonium amidated BS(PEG)5
annotated property: definition
annotated target: Ammonium amidated bis(sulfosuccinimidyl)suberate pentaethyleneglycol.
database_cross_reference: PSI:XL

hydrolyzed BSOCOES
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DPDPB
definition: Hydrolyzed bis(2-[Succinimidooxycarbonyloxy]ethyl) sulfone.
dead end formula: C6 H8 O7 S1
mono isotopic mass: 223.9990767
has_obo_namespace: XLMOD
id: XLMOD:01075

Axiom
annotated source: hydrolyzed BSOCOES
annotated property: definition
annotated target: Hydrolyzed bis(2-[Succinimidooxycarbonyloxy]ethyl) sulfone.
database_cross_reference: PSI:XL

ammonium amidated BSOCOES
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DPDPB
definition: Ammonium amidated bis(2-[Succinimidooxycarbonyloxy]ethyl) sulfone.
dead end formula: C6 H9 N1 O6 S1
mono isotopic mass: 223.015061105
has_obo_namespace: XLMOD
id: XLMOD:01076

Axiom
annotated source: ammonium amidated BSOCOES
annotated property: definition
annotated target: Ammonium amidated bis(2-[Succinimidooxycarbonyloxy]ethyl) sulfone.
database_cross_reference: PSI:XL

hydrolyzed DST
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DST
definition: Hydrolyzed disuccinimidyl tartrate.
dead end formula: C4 H4 O5
mono isotopic mass: 132.0058747
has_obo_namespace: XLMOD
id: XLMOD:01077

Axiom
annotated source: hydrolyzed DST
annotated property: definition
annotated target: Hydrolyzed disuccinimidyl tartrate.
database_cross_reference: PSI:XL

ammonium amidated DST
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: DST
definition: Ammonium amidated disuccinimidyl tartrate.
dead end formula: C4 H5 N1 O4
mono isotopic mass: 131.021859105
has_obo_namespace: XLMOD
id: XLMOD:01078

Axiom
annotated source: ammonium amidated DST
annotated property: definition
annotated target: Ammonium amidated disuccinimidyl tartrate.
database_cross_reference: PSI:XL

hydrolyzed SDA
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DMA
definition: Hydrolyzed succinimidyl-ester diazirine.
dead end formula: C5 H8 O2
mono isotopic mass: 100.05242954
has_obo_namespace: XLMOD
id: XLMOD:01079

Axiom
annotated source: hydrolyzed SDA
annotated property: definition
annotated target: Hydrolyzed succinimidyl-ester diazirine.
database_cross_reference: PSI:XL

oxidized SDA
type: Class
subclass of: oxidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: oxidized
subclass of: Restriction
  on property: is_side_product_of
  some values from: DMA
definition: Oxidized succinimidyl-ester diazirine.
dead end formula: C5 H6 O2
mono isotopic mass: 98.03677947
has_obo_namespace: XLMOD
id: XLMOD:01080

Axiom
annotated source: oxidized SDA
annotated property: definition
annotated target: Oxidized succinimidyl-ester diazirine.
database_cross_reference: PSI:XL

alkenized SDA
type: Class
subclass of: alkenized cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: alkenized
subclass of: Restriction
  on property: is_side_product_of
  some values from: DMA
definition: Alkenized succinimidyl-ester diazirine.
dead end formula: C4 H4 O1
mono isotopic mass: 68.02621477
has_obo_namespace: XLMOD
id: XLMOD:01081

Axiom
annotated source: alkenized SDA
annotated property: definition
annotated target: Alkenized succinimidyl-ester diazirine.
database_cross_reference: PSI:XL

hydrolyzed LC-SDA
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: DMP
definition: Hydrolyzed LC-SDA.
dead end formula: C11 H19 N1 O3
mono isotopic mass: 213.136493555
has_obo_namespace: XLMOD
id: XLMOD:01082

Axiom
annotated source: hydrolyzed LC-SDA
annotated property: definition
annotated target: Hydrolyzed LC-SDA.
database_cross_reference: PSI:XL

oxidized LC-SDA
type: Class
subclass of: oxidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: oxidized
subclass of: Restriction
  on property: is_side_product_of
  some values from: DMP
definition: Oxidized LC-SDA.
dead end formula: C11 H17 N1 O3
mono isotopic mass: 211.120843485
has_obo_namespace: XLMOD
id: XLMOD:01083

Axiom
annotated source: oxidized LC-SDA
annotated property: definition
annotated target: Oxidized LC-SDA.
database_cross_reference: PSI:XL

alkenized LC-SDA
type: Class
subclass of: alkenized cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: alkenized
subclass of: Restriction
  on property: is_side_product_of
  some values from: DMP
definition: Alkenized LC-SDA.
dead end formula: C10 H15 N1 O2
mono isotopic mass: 181.110278785
has_obo_namespace: XLMOD
id: XLMOD:01084

Axiom
annotated source: alkenized LC-SDA
annotated property: definition
annotated target: Alkenized LC-SDA.
database_cross_reference: PSI:XL

hydrolyzed L-Photo-Leucine
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Leucine
definition: Hydrolyzed L-2-amino-4,4-azi-pentanoic acid.
dead end formula: -C1 -H2 O1
mono isotopic mass: 1.97926456
has_obo_namespace: XLMOD
id: XLMOD:01085

Axiom
annotated source: hydrolyzed L-Photo-Leucine
annotated property: definition
annotated target: Hydrolyzed L-2-amino-4,4-azi-pentanoic acid.
database_cross_reference: PSI:XL

oxidized L-Photo-Leucine
type: Class
subclass of: oxidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: oxidized
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Leucine
definition: Oxidized L-2-amino-4,4-azi-pentanoic acid.
dead end formula: -C1 -H4 O1
mono isotopic mass: -0.036385501
has_obo_namespace: XLMOD
id: XLMOD:01086

Axiom
annotated source: oxidized L-Photo-Leucine
annotated property: definition
annotated target: Oxidized L-2-amino-4,4-azi-pentanoic acid.
database_cross_reference: PSI:XL

alkenized L-Photo-Leucine
type: Class
subclass of: alkenized cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: alkenized
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Leucine
definition: Alkenized L-2-amino-4,4-azi-pentanoic acid.
dead end formula: -C2 -H6
mono isotopic mass: -30.04695021
has_obo_namespace: XLMOD
id: XLMOD:01087

Axiom
annotated source: alkenized L-Photo-Leucine
annotated property: definition
annotated target: Alkenized L-2-amino-4,4-azi-pentanoic acid.
database_cross_reference: PSI:XL

hydrolyzed L-Photo-Methionine
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Methionine
definition: Hydrolyzed L-2-amino-5,5-azi-hexanoic acid.
dead end formula: C1 H2 O1 -S1
mono isotopic mass: -1.96150744
has_obo_namespace: XLMOD
id: XLMOD:01088

Axiom
annotated source: hydrolyzed L-Photo-Methionine
annotated property: definition
annotated target: Hydrolyzed L-2-amino-5,5-azi-hexanoic acid.
database_cross_reference: PSI:XL

oxidized L-Photo-Methionine
type: Class
subclass of: oxidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: oxidized
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Methionine
definition: Oxidized L-2-amino-5,5-azi-hexanoic acid.
dead end formula: C1 O1 -S1
mono isotopic mass: -3.97715607
has_obo_namespace: XLMOD
id: XLMOD:01089

Axiom
annotated source: oxidized L-Photo-Methionine
annotated property: definition
annotated target: Oxidized L-2-amino-5,5-azi-hexanoic acid.
database_cross_reference: PSI:XL

alkenized L-Photo-Methionine
type: Class
subclass of: alkenized cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: alkenized
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Methionine
definition: Alkenized L-2-amino-5,5-azi-hexanoic acid.
dead end formula: -H2 -S1
mono isotopic mass: -33.98772221
has_obo_namespace: XLMOD
id: XLMOD:01090

Axiom
annotated source: alkenized L-Photo-Methionine
annotated property: definition
annotated target: Alkenized L-2-amino-5,5-azi-hexanoic acid.
database_cross_reference: PSI:XL

hydrolyzed BMOE
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: THPP
definition: Hydrolyzed bis-Maleimidoethane.
has_obo_namespace: XLMOD
id: XLMOD:01091

Axiom
annotated source: hydrolyzed BMOE
annotated property: definition
annotated target: Hydrolyzed bis-Maleimidoethane.
database_cross_reference: PSI:XL

hydrolyzed BMPS
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: BMPS
definition: Hydrolyzed N-(beta-Maleimidopropyloxy)succinimide ester.
bridge formula: C7 H7 O4 N1
mono isotopic mass: 169.037507765
has_obo_namespace: XLMOD
id: XLMOD:01092

Axiom
annotated source: hydrolyzed BMPS
annotated property: definition
annotated target: Hydrolyzed N-(beta-Maleimidopropyloxy)succinimide ester.
database_cross_reference: PSI:XL

ammonium amidated BMPS
type: Class
subclass of: ammonium amidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: ammonium amidated
subclass of: Restriction
  on property: is_side_product_of
  some values from: BMPS
definition: Ammonium amidated N-(beta-Maleimidopropyloxy)succinimide ester.
bridge formula: C7 H8 O3 N2
mono isotopic mass: 168.05349217
has_obo_namespace: XLMOD
id: XLMOD:01093

Axiom
annotated source: ammonium amidated BMPS
annotated property: definition
annotated target: Ammonium amidated N-(beta-Maleimidopropyloxy)succinimide ester.
database_cross_reference: PSI:XL

hydrolyzed PDH
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: alkyne-A-DSBSO
definition: Hydrolyzed pimelic acid dihydrazide.
bridge formula: C7 H12 N4
mono isotopic mass: 170.11676112
has_obo_namespace: XLMOD
id: XLMOD:01094

Axiom
annotated source: hydrolyzed PDH
annotated property: definition
annotated target: Hydrolyzed pimelic acid dihydrazide.
database_cross_reference: PSI:XL

hydrolyzed PDH-d10
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: IML 3
definition: Deuterium labelled hydrolyzed pimelic acid dihydrazide.
bridge formula: C7 D10 H2 N4
doublet delta mass: 10.06276744
mono isotopic mass: 180.17952856
has_obo_namespace: XLMOD
id: XLMOD:01095

Axiom
annotated source: hydrolyzed PDH-d10
annotated property: definition
annotated target: Deuterium labelled hydrolyzed pimelic acid dihydrazide.
database_cross_reference: PSI:XL

hydrolyzed SuDP
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: SuDP
definition: Hydrolyzed disuccinimidyl-succinamyl-aspartyl-proline.
mono isotopic mass: 294.0852
has_obo_namespace: XLMOD
id: XLMOD:01096

Axiom
annotated source: hydrolyzed SuDP
annotated property: definition
annotated target: Hydrolyzed disuccinimidyl-succinamyl-aspartyl-proline.
database_cross_reference: PMID:26091612

hydrolyzed L-Photo-Isoleucine
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Isoleucine
definition: Hydrolyzed L-Photo-Isoleucine.
dead end formula: -C1 -H2 O1
mono isotopic mass: 1.97926456
has_obo_namespace: XLMOD
id: XLMOD:01097

Axiom
annotated source: hydrolyzed L-Photo-Isoleucine
annotated property: definition
annotated target: Hydrolyzed L-Photo-Isoleucine.
database_cross_reference: PSI:XL

oxidized L-Photo-Isoleucine
type: Class
subclass of: oxidation cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: oxidized
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Isoleucine
definition: Oxidized L-Photo-Isoleucine.
dead end formula: -C1 -H4 O1
mono isotopic mass: -0.036385501
has_obo_namespace: XLMOD
id: XLMOD:01098

Axiom
annotated source: oxidized L-Photo-Isoleucine
annotated property: definition
annotated target: Oxidized L-Photo-Isoleucine.
database_cross_reference: PSI:XL

alkenized L-Photo-Isoleucine
type: Class
subclass of: alkenized cross-linker related chemical modification
subclass of: Restriction
  on property: is_partially_reacted
  some values from: alkenized
subclass of: Restriction
  on property: is_side_product_of
  some values from: L-Photo-Isoleucine
definition: Alkenized L-Photo-Isoleucine.
dead end formula: -C2 -H6
mono isotopic mass: -30.04695021
has_obo_namespace: XLMOD
id: XLMOD:01099

Axiom
annotated source: alkenized L-Photo-Isoleucine
annotated property: definition
annotated target: Alkenized L-Photo-Isoleucine.
database_cross_reference: PSI:XL

hydrolyzed Sulfo-SBED
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: Sulfo-SBED
definition: Hydrolyzed Sulfo-SBED cross-linker.
mono isotopic mass: 652.217
has_obo_namespace: XLMOD
id: XLMOD:01100

Axiom
annotated source: hydrolyzed Sulfo-SBED
annotated property: definition
annotated target: Hydrolyzed Sulfo-SBED cross-linker.
database_cross_reference: PMID:16246579

hydrolyzed PIR
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: PIR
CID fragment: 828.5
definition: Hydrolized Protein Interaction Reporter.
has_obo_namespace: XLMOD
id: XLMOD:01101

Axiom
annotated source: hydrolyzed PIR
annotated property: definition
annotated target: Hydrolized Protein Interaction Reporter.
database_cross_reference: PMID:15623310

hydrolized PL
type: Class
subclass of: hydrolization cross-linker related chemical modification
subclass of: Restriction
  on property: is_cleavable
  some values from: photocleavable
subclass of: Restriction
  on property: is_partially_reacted
  some values from: hydrolyzed
subclass of: Restriction
  on property: is_side_product_of
  some values from: PL
definition: Hydrolyzed photo-cleavable Leiker.
mono isotopic mass: 334.15
has_obo_namespace: XLMOD
id: XLMOD:01102

Axiom
annotated source: hydrolized PL
annotated property: definition
annotated target: Hydrolyzed photo-cleavable Leiker.
database_cross_reference: PMID:26952210
database_cross_reference: PMID:27734140

8-methoxypsoralen
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: 8-methoxypsoralen reagent.
reaction sites: 1
has_exact_synonym: 8-MOP
has_obo_namespace: XLMOD
id: XLMOD:01700

Axiom
annotated source: 8-methoxypsoralen
annotated property: definition
annotated target: 8-methoxypsoralen reagent.
database_cross_reference: CAS:298-81-7
database_cross_reference: ChemSpiderID:3971
database_cross_reference: ChemicalBookNo:CB6733540
database_cross_reference: PMID:9013628
database_cross_reference: PubChem_Compound:4114

4'-hydroxymethyl-4,5'8-trimethylpsoralen
type: Class
subclass of: reactive group
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: 4'-hydroxymethyl-4,5'8-trimethylpsoralen reagent.
reaction sites: 1
has_exact_synonym: HMT
has_obo_namespace: XLMOD
id: XLMOD:01701

Axiom
annotated source: 4'-hydroxymethyl-4,5'8-trimethylpsoralen
annotated property: definition
annotated target: 4'-hydroxymethyl-4,5'8-trimethylpsoralen reagent.
database_cross_reference: CAS:62442-59-5
database_cross_reference: ChemSpiderID:94710
database_cross_reference: ChemicalBookNo:CB7358269
database_cross_reference: MDL:MFCD00036888
database_cross_reference: PMID:9013628
database_cross_reference: PubChem_Compound:104953

5-iodouracil
type: Class
subclass of: nucleobase derivative
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: uracil
definition: 5-iodouracil reagent.
reaction sites: 1
has_exact_synonym: 5-IU
has_exact_synonym: 5IU
has_obo_namespace: XLMOD
id: XLMOD:01702

Axiom
annotated source: 5-iodouracil
annotated property: definition
annotated target: 5-iodouracil reagent.
database_cross_reference: CAS:696-07-1
database_cross_reference: ChemSpiderID:62873
database_cross_reference: ChemicalBookNo:CB8771577
database_cross_reference: MDL:MFCD00006020
database_cross_reference: PMID:12476441
database_cross_reference: PMID:9013628
database_cross_reference: PubChem_Compound:69672

4-thiouracil
type: Class
subclass of: nucleobase derivative
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: uracil
definition: 4-thiouracil reagent.
reaction sites: 1
has_exact_synonym: 4-SU
has_exact_synonym: 4SU
has_obo_namespace: XLMOD
id: XLMOD:01703

Axiom
annotated source: 4-thiouracil
annotated property: definition
annotated target: 4-thiouracil reagent.
database_cross_reference: CAS:591-28-6
database_cross_reference: ChemSpiderID:2016146
database_cross_reference: ChemicalBookNo:CB4469328
database_cross_reference: MDL:MFCD00090842
database_cross_reference: PMID:12476441
database_cross_reference: PMID:22575267
database_cross_reference: PubChem_Compound:2734394

6-thioguanosine
type: Class
subclass of: nucleoside derivative
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: guanosine
definition: 6-thioguanosine reagent.
reaction sites: 1
has_exact_synonym: 6-SG
has_exact_synonym: 6SG
has_obo_namespace: XLMOD
id: XLMOD:01704

Axiom
annotated source: 6-thioguanosine
annotated property: definition
annotated target: 6-thioguanosine reagent.
database_cross_reference: CAS:85-31-4
database_cross_reference: ChemSpiderID:2006534
database_cross_reference: ChemicalBookNo:CB3722231
database_cross_reference: PMID:20946768
database_cross_reference: PMID:22575267
database_cross_reference: PubChem_Compound:2724387

5-bromouracil
type: Class
subclass of: nucleobase derivative
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: uracil
definition: 5-bromouracil reagent.
reaction sites: 1
has_exact_synonym: 5-BU
has_exact_synonym: 5BU
has_obo_namespace: XLMOD
id: XLMOD:01705

Axiom
annotated source: 5-bromouracil
annotated property: definition
annotated target: 5-bromouracil reagent.
database_cross_reference: Beilstein:127176
database_cross_reference: CAS:51-20-7
database_cross_reference: ChemSpiderID:5597
database_cross_reference: ChemicalBookNo:CB6388195
database_cross_reference: MDL:MFCD00006017
database_cross_reference: PMID:22575267
database_cross_reference: PMID:9145285
database_cross_reference: PubChem_Compound:5802

5-iodocytosine
type: Class
subclass of: nucleoside derivative
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: cytosine
definition: 5-iodocytosine reagent.
reaction sites: 1
has_exact_synonym: 5-IC
has_exact_synonym: 5IC
has_obo_namespace: XLMOD
id: XLMOD:01706

Axiom
annotated source: 5-iodocytosine
annotated property: definition
annotated target: 5-iodocytosine reagent.
database_cross_reference: CAS:1122-44-7
database_cross_reference: ChemSpiderID:13643
database_cross_reference: ChemicalBookNo:CB9203633
database_cross_reference: MDL:MFCD00023162
database_cross_reference: PMID:9145285
database_cross_reference: PubChem_Compound:14281

8-azidoadenosine
type: Class
subclass of: nucleoside derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: adenosine
definition: 8-azidoadenosine reagent.
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01707

Axiom
annotated source: 8-azidoadenosine
annotated property: definition
annotated target: 8-azidoadenosine reagent.
database_cross_reference: CAS:4372-67-2
database_cross_reference: ChemSpiderID:141244
database_cross_reference: ChemicalBookNo:CB7166563
database_cross_reference: PMID:9145285

2-azidoadenosine
type: Class
subclass of: nucleoside derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: adenosine
definition: 2-azidoadenosine reagent.
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01708

Axiom
annotated source: 2-azidoadenosine
annotated property: definition
annotated target: 2-azidoadenosine reagent.
database_cross_reference: CAS:59587-07-4
database_cross_reference: ChemicalBookNo:CB01175626
database_cross_reference: PMID:9145285
database_cross_reference: PubChem_Compound:510978

8-azidoguanosine
type: Class
subclass of: nucleoside derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: guanosine
definition: 8-azidoguanosine reagent.
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01709

Axiom
annotated source: 8-azidoguanosine
annotated property: definition
annotated target: 8-azidoguanosine reagent.
database_cross_reference: ChemSpiderID:8034117
database_cross_reference: PMID:9145285
database_cross_reference: PubChem_Compound:23375450

5-azidouridine
type: Class
subclass of: nucleoside derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: uridine
definition: 5-azidouridine reagent.
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01710

Axiom
annotated source: 5-azidouridine
annotated property: definition
annotated target: 5-azidouridine reagent.
database_cross_reference: CAS:1261272-24-5
database_cross_reference: ChemSpiderID:18697526
database_cross_reference: ChemicalBookNo:CB62543444
database_cross_reference: PMID:9145285
database_cross_reference: PubChem_Compound:20832934

bis-[3-(2-ketobutyraldehyde)ether
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: glyoxal
definition: bis-[3-(2-ketobutyraldehyde)ether reagent.
mono isotopic mass: 230.079
reaction sites: 2
spacer length: 5.4
has_exact_synonym: BKT
has_exact_synonym: Bikethoxal
has_obo_namespace: XLMOD
id: XLMOD:01711

Axiom
annotated source: bis-[3-(2-ketobutyraldehyde)ether
annotated property: definition
annotated target: bis-[3-(2-ketobutyraldehyde)ether reagent.
database_cross_reference: CAS:84031-85-6
database_cross_reference: ChemSpiderID:118706
database_cross_reference: ChemicalBookNo:CB81338982
database_cross_reference: PMID:16875836
database_cross_reference: PubChem_Compound:134685

mechlorethamine
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: chloroethyl
definition: Mechlorethamine reagent.
mono isotopic mass: 83.073
reaction sites: 2
spacer length: 9.5
has_exact_synonym: NM
has_exact_synonym: Nitrogen mustard
has_obo_namespace: XLMOD
id: XLMOD:01712

Axiom
annotated source: mechlorethamine
annotated property: definition
annotated target: Mechlorethamine reagent.
database_cross_reference: CAS:55-86-7
database_cross_reference: ChemSpiderID:3893
database_cross_reference: ChemicalBookNo:CB5270716
database_cross_reference: MDL:MFCD00012517
database_cross_reference: PMID:16875836
database_cross_reference: PubChem_Compound:4033

4-[bis-(2-chloroethyl)amino]benzenebutanoic acid
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: chloroethyl
definition: 4-[bis-(2-chloroethyl)amino]benzenebutanoic acid reagent.
mono isotopic mass: 231.126
reaction sites: 2
spacer length: 9.5
has_exact_synonym: CHB
has_exact_synonym: Chlorambucil
has_obo_namespace: XLMOD
id: XLMOD:01713

Axiom
annotated source: 4-[bis-(2-chloroethyl)amino]benzenebutanoic acid
annotated property: definition
annotated target: 4-[bis-(2-chloroethyl)amino]benzenebutanoic acid reagent.
database_cross_reference: Beilstein:999011
database_cross_reference: CAS:305-03-3
database_cross_reference: ChemSpiderID:2607
database_cross_reference: ChemicalBookNo:CB5270716
database_cross_reference: MDL:MFCD00021783
database_cross_reference: PMID:16875836
database_cross_reference: PubChem_Compound:2708

sym-triazine trichloride
type: Class
subclass of: homofunctional cross-linker
definition: Sym-triazine trichloride reagent.
mono isotopic mass: 110.962
reaction sites: 2
spacer length: 2.4
has_exact_synonym: Cyanuric acid
has_exact_synonym: STT
has_obo_namespace: XLMOD
id: XLMOD:01714

Axiom
annotated source: sym-triazine trichloride
annotated property: definition
annotated target: Sym-triazine trichloride reagent.
database_cross_reference: Beilstein:126982
database_cross_reference: CAS:108-80-5
database_cross_reference: ChemSpiderID:7668
database_cross_reference: ChemicalBookNo:CB5852763
database_cross_reference: MDL:MFCD00082990
database_cross_reference: PMID:16875836
database_cross_reference: PubChem_Compound:24851182

Heteroconjugate 20
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
definition: Heteroconjugate 20 reagent.
mono isotopic mass: 1554.6871
reaction sites: 2
has_exact_synonym: HC20
has_obo_namespace: XLMOD
id: XLMOD:01715

Axiom
annotated source: Heteroconjugate 20
annotated property: definition
annotated target: Heteroconjugate 20 reagent.
database_cross_reference: PMID:26335278

benzophenone-4-iodoacetamide
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: Benzophenone-4-iodoacetamide reagent.
reaction sites: 1
has_exact_synonym: BPI
has_obo_namespace: XLMOD
id: XLMOD:01716

Axiom
annotated source: benzophenone-4-iodoacetamide
annotated property: definition
annotated target: Benzophenone-4-iodoacetamide reagent.
database_cross_reference: CAS:76809-63-7
database_cross_reference: ChemicalBookNo:CB3488704
database_cross_reference: PMID:10208813
database_cross_reference: PubChem_Compound:131289

azidophenacyl bromide
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_fluorophore
  some values from: phenacyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: Azidophenacyl bromide reagent.
reaction sites: 1
has_exact_synonym: APB
has_obo_namespace: XLMOD
id: XLMOD:01717

Axiom
annotated source: azidophenacyl bromide
annotated property: definition
annotated target: Azidophenacyl bromide reagent.
database_cross_reference: Beilstein:1961705
database_cross_reference: CAS:57018-46-9
database_cross_reference: ChemSpiderID:83619
database_cross_reference: ChemicalBookNo:CB3120420
database_cross_reference: MDL:MFCD00042637
database_cross_reference: PMID:10208813
database_cross_reference: PubChem_Compound:92627

benzophenone-phosphatidylcholine
type: Class
subclass of: lipid analogue
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: Benzophenone-phosphatidylcholine.
reaction sites: 1
has_exact_synonym: benzophenone-PC
has_obo_namespace: XLMOD
id: XLMOD:01718

Axiom
annotated source: benzophenone-phosphatidylcholine
annotated property: definition
annotated target: Benzophenone-phosphatidylcholine.
database_cross_reference: PMID:19171301

phenylazide-phosphatidylcholine
type: Class
subclass of: lipid analogue
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: Phenylazide-phosphatidylcholine.
reaction sites: 1
has_exact_synonym: phenylazide-PC
has_obo_namespace: XLMOD
id: XLMOD:01719

Axiom
annotated source: phenylazide-phosphatidylcholine
annotated property: definition
annotated target: Phenylazide-phosphatidylcholine.
database_cross_reference: PMID:19171301

N-(4-azidosalicylamidyl)-1,2-dilauroyl-sn-glycero-3-phosphoethanolamine
type: Class
subclass of: lipid analogue
definition: The N-(4-azidosalicylamidyl)-1,2-dilauroyl-sn-glycero-3-phosphoethanolamine lipid analogue used for lipid-protein cross-linking.
has_exact_synonym: ASA
has_obo_namespace: XLMOD
id: XLMOD:01720

Axiom
annotated source: N-(4-azidosalicylamidyl)-1,2-dilauroyl-sn-glycero-3-phosphoethanolamine
annotated property: definition
annotated target: The N-(4-azidosalicylamidyl)-1,2-dilauroyl-sn-glycero-3-phosphoethanolamine lipid analogue used for lipid-protein cross-linking.
database_cross_reference: PMID:19171301

Ac5-5-SiaDAz
type: Class
subclass of: sialic acid analogue
definition: The Ac5-5-SiaDAz sialic acid analogue used for glycan-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:01721

Axiom
annotated source: Ac5-5-SiaDAz
annotated property: definition
annotated target: The Ac5-5-SiaDAz sialic acid analogue used for glycan-protein cross-linking.
database_cross_reference: PMID:18293988
database_cross_reference: PMID:19536272

Ac4-ManNDAz
type: Class
subclass of: sialic acid analogue
definition: The Ac4-ManNDAz sialic acid analogue used for glycan-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:01722

Axiom
annotated source: Ac4-ManNDAz
annotated property: definition
annotated target: The Ac4-ManNDAz sialic acid analogue used for glycan-protein cross-linking.
database_cross_reference: PMID:18293988
database_cross_reference: PMID:19536272
database_cross_reference: PMID:20816498

Ac4-ManNAc
type: Class
subclass of: sialic acid analogue
definition: The Ac4-ManNAc sialic acid analogue used for glycan-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:01723

Axiom
annotated source: Ac4-ManNAc
annotated property: definition
annotated target: The Ac4-ManNAc sialic acid analogue used for glycan-protein cross-linking.
database_cross_reference: PMID:19536272

Ac4-GlcNDAz
type: Class
subclass of: sialic acid analogue
definition: The Ac4-GlcNDAz sialic acid analogue used for glycan-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:01724

Axiom
annotated source: Ac4-GlcNDAz
annotated property: definition
annotated target: The Ac4-GlcNDAz sialic acid analogue used for glycan-protein cross-linking.
database_cross_reference: PMID:19536272
database_cross_reference: PMID:20816498

Ac5-methyl-SiaDAz
type: Class
subclass of: sialic acid analogue
definition: The Ac5-methyl-SiaDAz sialic acid analogue used for glycan-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:01725

Axiom
annotated source: Ac5-methyl-SiaDAz
annotated property: definition
annotated target: The Ac5-methyl-SiaDAz sialic acid analogue used for glycan-protein cross-linking.
database_cross_reference: PMID:20816498

sialylated LacNAc-biotin
type: Class
subclass of: sialic acid analogue
definition: Sialylated LacNAc-biotin used for glycan-protein cross-linking.
has_obo_namespace: XLMOD
id: XLMOD:01726

Axiom
annotated source: sialylated LacNAc-biotin
annotated property: definition
annotated target: Sialylated LacNAc-biotin used for glycan-protein cross-linking.
database_cross_reference: PMID:26541974

Psoralen-PEG3-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: psoralen
definition: Psoralen-PEG3-Biotin biotinylation reagent.
hydrophilic PE gchain: 3
reaction sites: 1
spacer length: 36.86
has_obo_namespace: XLMOD
id: XLMOD:01800

Axiom
annotated source: Psoralen-PEG3-Biotin
annotated property: definition
annotated target: Psoralen-PEG3-Biotin biotinylation reagent.
database_cross_reference: PSI:XL

Photoactivatable Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: Photoactivatable Biotin biotinylation reagent.
reaction sites: 1
spacer length: 30.0
has_obo_namespace: XLMOD
id: XLMOD:01801

Axiom
annotated source: Photoactivatable Biotin
annotated property: definition
annotated target: Photoactivatable Biotin biotinylation reagent.
database_cross_reference: PSI:XL

TFPA-PEG3-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: tetrafluorophenyl azide
definition: TFPA-PEG3-Biotin biotinylation reagent.
hydrophilic PE gchain: 3
reaction sites: 1
spacer length: 33.4
has_obo_namespace: XLMOD
id: XLMOD:01802

Axiom
annotated source: TFPA-PEG3-Biotin
annotated property: definition
annotated target: TFPA-PEG3-Biotin biotinylation reagent.
database_cross_reference: CAS:1264662-85-2
database_cross_reference: ChemSpiderID:59757057

Biotin-LC-ASA
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
definition: 1-(4-azidosalicylamido)-6(biotinamido)-hexane.
reaction sites: 1
spacer length: 29.9
has_exact_synonym: Biotin-Long Chain-ASA
has_obo_namespace: XLMOD
id: XLMOD:01803

Axiom
annotated source: Biotin-LC-ASA
annotated property: definition
annotated target: 1-(4-azidosalicylamido)-6(biotinamido)-hexane.
database_cross_reference: ChemicalBookNo:CB9438943

Sulfo-NHS-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
definition: Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt.
reaction sites: 1
spacer length: 13.5
has_exact_synonym: N-Hydroxysulfosuccinimidobiotin
has_exact_synonym: Sulfosuccinimidyl biotin
has_obo_namespace: XLMOD
id: XLMOD:01804

Axiom
annotated source: Sulfo-NHS-Biotin
annotated property: definition
annotated target: Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt.
database_cross_reference: CAS:119616-38-5
database_cross_reference: ChemSpiderID:28568147
database_cross_reference: ChemicalBookNo:CB8277468
database_cross_reference: PubChem_Compound:56846292

Sulfo-NHS-LC-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
definition: Sulfo-NHS-LC-Biotin biotinylation reagent.
reaction sites: 1
spacer length: 22.4
has_exact_synonym: Long chain Sulfo-NHS-Biotin
has_obo_namespace: XLMOD
id: XLMOD:01805

Axiom
annotated source: Sulfo-NHS-LC-Biotin
annotated property: definition
annotated target: Sulfo-NHS-LC-Biotin biotinylation reagent.
database_cross_reference: CAS:127062-22-0
database_cross_reference: ChemSpiderID:29788101
database_cross_reference: ChemicalBookNo:CB7387089
database_cross_reference: PubChem_Compound:71571497

NHS-PEG12-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: NHS-PEG12-Biotin biotinylation reagent.
hydrophilic PE gchain: 12
reaction sites: 1
spacer length: 56.0
has_exact_synonym: Biotin-PEG12-NHS ester
has_obo_namespace: XLMOD
id: XLMOD:01806

Axiom
annotated source: NHS-PEG12-Biotin
annotated property: definition
annotated target: NHS-PEG12-Biotin biotinylation reagent.
database_cross_reference: CAS:365441-71-0
database_cross_reference: ChemSpiderID:29354431
database_cross_reference: ChemicalBookNo:CB52546796
database_cross_reference: PubChem_Compound:58481068

NHS-SS-PEG4-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: NHS-SS-PEG4-Biotin biotinylation reagent.
hydrophilic PE gchain: 4
reaction sites: 1
spacer length: 37.9
has_obo_namespace: XLMOD
id: XLMOD:01807

Axiom
annotated source: NHS-SS-PEG4-Biotin
annotated property: definition
annotated target: NHS-SS-PEG4-Biotin biotinylation reagent.
database_cross_reference: PSI:XL

NHS-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Biotin N-hydroxysuccinimide ester.
reaction sites: 1
spacer length: 13.5
has_obo_namespace: XLMOD
id: XLMOD:01808

Axiom
annotated source: NHS-Biotin
annotated property: definition
annotated target: Biotin N-hydroxysuccinimide ester.
database_cross_reference: CAS:35013-72-0
database_cross_reference: ChemSpiderID:5142865
database_cross_reference: ChemicalBookNo:CB7371998
database_cross_reference: PubChem_Compound:434213

NHS-LC-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester.
reaction sites: 1
spacer length: 30.5
has_obo_namespace: XLMOD
id: XLMOD:01809

Axiom
annotated source: NHS-LC-Biotin
annotated property: definition
annotated target: Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester.
database_cross_reference: CAS:89889-52-1
database_cross_reference: ChemSpiderID:17346377
database_cross_reference: ChemicalBookNo:CB1412590
database_cross_reference: PubChem_Compound:4072290

NHS-SS-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Biotin disulfide N-hydroxysuccinimide ester.
reaction sites: 1
spacer length: 24.3
has_obo_namespace: XLMOD
id: XLMOD:01810

Axiom
annotated source: NHS-SS-Biotin
annotated property: definition
annotated target: Biotin disulfide N-hydroxysuccinimide ester.
database_cross_reference: CAS:142439-92-7
database_cross_reference: ChemSpiderID:3405732
database_cross_reference: ChemicalBookNo:CB4216304
database_cross_reference: PubChem_Compound:71312116

NHS-Iminobiotin trifluoroacetamide
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: iminobiotintrifluoroacetamide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: NHS-Iminobiotin trifluoroacetamide biotinylation reagent.
reaction sites: 1
spacer length: 13.5
has_obo_namespace: XLMOD
id: XLMOD:01811

Axiom
annotated source: NHS-Iminobiotin trifluoroacetamide
annotated property: definition
annotated target: NHS-Iminobiotin trifluoroacetamide biotinylation reagent.
database_cross_reference: ChemicalBookNo:CB6315012

PFP-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: pentafluorophenyl
definition: Pentafluorophenyl-Biotin.
reaction sites: 1
spacer length: 9.6
has_exact_synonym: Biotin-PFP-ester
has_obo_namespace: XLMOD
id: XLMOD:01812

Axiom
annotated source: PFP-Biotin
annotated property: definition
annotated target: Pentafluorophenyl-Biotin.
database_cross_reference: CAS:120550-35-8
database_cross_reference: ChemSpiderID:9297574
database_cross_reference: ChemicalBookNo:CB6307189
database_cross_reference: PubChem_Compound:11122445

TFP-PEG3-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: tetrafluorophenyl ester
definition: Tetrafluorophenyl-PEG3-Biotin.
hydrophilic PE gchain: 3
reaction sites: 1
spacer length: 32.6
has_obo_namespace: XLMOD
id: XLMOD:01813

Axiom
annotated source: TFP-PEG3-Biotin
annotated property: definition
annotated target: Tetrafluorophenyl-PEG3-Biotin.
database_cross_reference: PSI:XL

Maleimide-PEG11-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Maleimide-PEG11-Biotin biotinylation reagent.
hydrophilic PE gchain: 11
reaction sites: 1
spacer length: 59.1
has_obo_namespace: XLMOD
id: XLMOD:01814

Axiom
annotated source: Maleimide-PEG11-Biotin
annotated property: definition
annotated target: Maleimide-PEG11-Biotin biotinylation reagent.
database_cross_reference: PSI:XL

Biotin-BMCC
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 1-Biotinamido-4-[4´-(maleimidomethyl)cyclohexanecarboxamido]butane.
reaction sites: 1
spacer length: 32.6
has_obo_namespace: XLMOD
id: XLMOD:01815

Axiom
annotated source: Biotin-BMCC
annotated property: definition
annotated target: 1-Biotinamido-4-[4´-(maleimidomethyl)cyclohexanecarboxamido]butane.
database_cross_reference: ChemicalBookNo:CB5366406

Iodoacetyl-PEG2-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: iodoacetyl
definition: Iodoacetyl-PEG2-Biotin biotinylation reagent.
hydrophilic PE gchain: 2
reaction sites: 1
spacer length: 24.7
has_obo_namespace: XLMOD
id: XLMOD:01816

Axiom
annotated source: Iodoacetyl-PEG2-Biotin
annotated property: definition
annotated target: Iodoacetyl-PEG2-Biotin biotinylation reagent.
database_cross_reference: PSI:XL

Iodoacetyl-LC-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: iodoacetyl
definition: Iodoacetyl-LC-Biotin biotinylation reagent.
reaction sites: 1
spacer length: 27.1
has_obo_namespace: XLMOD
id: XLMOD:01817

Axiom
annotated source: Iodoacetyl-LC-Biotin
annotated property: definition
annotated target: Iodoacetyl-LC-Biotin biotinylation reagent.
database_cross_reference: CAS:93285-75-7
database_cross_reference: ChemSpiderID:4248811
database_cross_reference: ChemicalBookNo:CB5664328
database_cross_reference: PubChem_Compound:125043

Pentylamine-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: pentylamine
definition: 5-(Biotinamido)pentylamine.
reaction sites: 1
spacer length: 18.9
has_obo_namespace: XLMOD
id: XLMOD:01818

Axiom
annotated source: Pentylamine-Biotin
annotated property: definition
annotated target: 5-(Biotinamido)pentylamine.
database_cross_reference: CAS:115416-38-1
database_cross_reference: ChemSpiderID:75715
database_cross_reference: ChemicalBookNo:CB8415868
database_cross_reference: PubChem_Compound:83906

Amine-PEG2-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: 5-(Biotinamido)pentylamine.
hydrophilic PE gchain: 2
reaction sites: 1
spacer length: 20.4
has_exact_synonym: Biotin-PEG2-amine
has_obo_namespace: XLMOD
id: XLMOD:01819

Axiom
annotated source: Amine-PEG2-Biotin
annotated property: definition
annotated target: 5-(Biotinamido)pentylamine.
database_cross_reference: PubChem_Compound:11199678

Amine-PEG3-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: Amine-PEG3-Biotin biotinylation reagent.
hydrophilic PE gchain: 3
reaction sites: 1
spacer length: 22.9
has_exact_synonym: Biotin-PEG3-amine
has_obo_namespace: XLMOD
id: XLMOD:01820

Axiom
annotated source: Amine-PEG3-Biotin
annotated property: definition
annotated target: Amine-PEG3-Biotin biotinylation reagent.
database_cross_reference: PubChem_Compound:53384310

Biocytine-Hydrazide
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Biocytine-Hydrazide biotinylation reagent.
reaction sites: 1
spacer length: 19.7
has_obo_namespace: XLMOD
id: XLMOD:01821

Axiom
annotated source: Biocytine-Hydrazide
annotated property: definition
annotated target: Biocytine-Hydrazide biotinylation reagent.
database_cross_reference: CS:102743-85-1
database_cross_reference: PubChem_Compound:128197

Biotin-Hydrazide
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Biocytine-Hydrazide biotinylation reagent.
reaction sites: 1
spacer length: 15.7
has_obo_namespace: XLMOD
id: XLMOD:01822

Axiom
annotated source: Biotin-Hydrazide
annotated property: definition
annotated target: Biocytine-Hydrazide biotinylation reagent.
database_cross_reference: CAS:66640-86-6
database_cross_reference: ChemSpiderID:75684
database_cross_reference: ChemicalBookNo:CB3175354
database_cross_reference: PubChem_Compound:83872

Biotin-LC-Hydrazide
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Long chain Biocytine-Hydrazide biotinylation reagent.
reaction sites: 1
spacer length: 24.7
has_exact_synonym: Biotin-LC-Hz
has_obo_namespace: XLMOD
id: XLMOD:01823

Axiom
annotated source: Biotin-LC-Hydrazide
annotated property: definition
annotated target: Long chain Biocytine-Hydrazide biotinylation reagent.
database_cross_reference: CAS:109276-34-8
database_cross_reference: ChemSpiderID:75709
database_cross_reference: ChemicalBookNo:CB4309220
database_cross_reference: PubChem_Compound:3504484

Biotin-PEG4-Hydrazide
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Biotin-PEG4-Hydrazide biotinylation reagent.
hydrophilic PE gchain: 4
reaction sites: 1
spacer length: 31.3
has_obo_namespace: XLMOD
id: XLMOD:01824

Axiom
annotated source: Biotin-PEG4-Hydrazide
annotated property: definition
annotated target: Biotin-PEG4-Hydrazide biotinylation reagent.
database_cross_reference: PubChem_Compound:51340934

Photobiotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
definition: Photoactivatable Biotin.
reaction sites: 1
spacer length: 30.0
has_obo_namespace: XLMOD
id: XLMOD:01825

Axiom
annotated source: Photobiotin
annotated property: definition
annotated target: Photoactivatable Biotin.
database_cross_reference: CAS:96087-37-5
database_cross_reference: ChemSpiderID:2299671
database_cross_reference: ChemicalBookNo:CB7301795
database_cross_reference: PubChem_Compound:15949227

Biotin-PEG2-Alkyne
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_handle
  some values from: alkyne
subclass of: Restriction
  on property: is_cleavable
  some values from: photo cleavable
definition: Biotin-PEG2-Alkyne.
hydrophilic PE gchain: 2
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01826

Axiom
annotated source: Biotin-PEG2-Alkyne
annotated property: definition
annotated target: Biotin-PEG2-Alkyne.
database_cross_reference: PubChem_Compound:91757772

Biotin-PEG2-C4-Alkyne
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_handle
  some values from: alkyne
subclass of: Restriction
  on property: is_cleavable
  some values from: photo cleavable
definition: Biotin-PEG2-C4-Alkyne.
hydrophilic PE gchain: 2
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01827

Axiom
annotated source: Biotin-PEG2-C4-Alkyne
annotated property: definition
annotated target: Biotin-PEG2-C4-Alkyne.
database_cross_reference: CAS:109276-34-8
database_cross_reference: ChemSpiderID:75709
database_cross_reference: ChemicalBookNo:CB73062389
database_cross_reference: PubChem_Compound:91757769

Biotin-PEG4-Alkyne
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_handle
  some values from: alkyne
subclass of: Restriction
  on property: is_cleavable
  some values from: photo cleavable
definition: Biotin-PEG4-Alkyne.
hydrophilic PE gchain: 4
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01828

Axiom
annotated source: Biotin-PEG4-Alkyne
annotated property: definition
annotated target: Biotin-PEG4-Alkyne.
database_cross_reference: CAS:1458576-00-5
database_cross_reference: ChemicalBookNo:CB82984377
database_cross_reference: PubChem_Compound:75409985

2-iminothiolane
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: imino
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: 2-iminothiolane reagent.
reaction sites: 1
has_exact_synonym: Traut's reagent
has_obo_namespace: XLMOD
id: XLMOD:01829

Axiom
annotated source: 2-iminothiolane
annotated property: definition
annotated target: 2-iminothiolane reagent.
database_cross_reference: CAS:4781-83-3
database_cross_reference: ChemSpiderID:10732937
database_cross_reference: ChemicalBookNo:CB7373482
database_cross_reference: MDL:MFCD00039013
database_cross_reference: PMID:11350598
database_cross_reference: PMID:6170935
database_cross_reference: PubChem_Compound:433941

3-Azidopyridine-adenine dinucleotide
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: 3-Azidopyridine-adenine dinucleotide reagent.
reaction sites: 1
has_exact_synonym: APA
has_obo_namespace: XLMOD
id: XLMOD:01830

Axiom
annotated source: 3-Azidopyridine-adenine dinucleotide
annotated property: definition
annotated target: 3-Azidopyridine-adenine dinucleotide reagent.
database_cross_reference: CAS:50695-15-3
database_cross_reference: ChemSpiderID:164324
database_cross_reference: ChemicalBookNo:CB91349828
database_cross_reference: MDL:MFCD00078882
database_cross_reference: PMID:20946768
database_cross_reference: PMID:6770736
database_cross_reference: PubChem_Compound:189126

L-Photo-Leucine
type: Class
subclass of: amino acid derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: L-Leucine
definition: L-2-amino-4,4-azi-pentanoic acid.
bridge formula: -C1 -H4
mono isotopic mass: -16.0313
reaction sites: 1
has_exact_synonym: L-Photo-Leu
has_obo_namespace: XLMOD
id: XLMOD:01900
comment: A photoreactive amino acid analog of L-Leucine for incorporation during protein synthesis that can be used for in vivo labelling, cross-linking and protein-protein interaction studies in live cells.

Axiom
annotated source: L-Photo-Leucine
annotated property: definition
annotated target: L-2-amino-4,4-azi-pentanoic acid.
database_cross_reference: CAS:851960-91-3
database_cross_reference: ChemSpiderID:32980228
database_cross_reference: PMID:15782218
database_cross_reference: PMID:26700045

L-Photo-Methionine
type: Class
subclass of: amino acid derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: L-Methionine
definition: L-2-amino-5,5-azi-hexanoic acid.
bridge formula: C1 -S1
mono isotopic mass: -19.972072
reaction sites: 1
has_exact_synonym: L-Photo-Met
has_obo_namespace: XLMOD
id: XLMOD:01901
comment: A photoreactive amino acid analog of L-Methionine for incorporation during protein synthesis that can be used for in vivo labelling, cross-linking and protein-protein interaction studies in live cells.

Axiom
annotated source: L-Photo-Methionine
annotated property: definition
annotated target: L-2-amino-5,5-azi-hexanoic acid.
database_cross_reference: CAS:851960-68-4
database_cross_reference: ChemSpiderID:61327213
database_cross_reference: PMID:15782218
database_cross_reference: PMID:26700045

L-Photo-Isoleucine
type: Class
subclass of: amino acid derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: L-Isoleucine
definition: L-Photo-Isoleucine.
bridge formula: -C1 -H4
mono isotopic mass: -16.0313
reaction sites: 1
has_exact_synonym: L-Photo-Ile
has_obo_namespace: XLMOD
id: XLMOD:01902
comment: A photoreactive amino acid analog of L-Isoleucine for incorporation during protein synthesis that can be used for in vivo labelling, cross-linking and protein-protein interaction studies in live cells.

Axiom
annotated source: L-Photo-Isoleucine
annotated property: definition
annotated target: L-Photo-Isoleucine.
database_cross_reference: PMID:16477643

pBpa
type: Class
subclass of: amino acid derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: L-Phenylalanine
definition: p-benzoyl-L-phenylalanine.
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01903
comment: A photoreactive amino acid analog of L-Phenylalanine for incorporation during protein synthesis that can be used for in vivo labelling, cross-linking and protein-protein interaction studies in live cells.

Axiom
annotated source: pBpa
annotated property: definition
annotated target: p-benzoyl-L-phenylalanine.
database_cross_reference: PMID:16170867

pBpa-d11
type: Class
subclass of: amino acid derivative
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
subclass of: Restriction
  on property: is_analog_of
  some values from: L-Phenylalanine
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled p-benzoyl-L-phenylalanine.
reaction sites: 1
has_obo_namespace: XLMOD
id: XLMOD:01904
comment: A photoreactive deuterium-labelled amino acid analog of L-Phenylalanine for incorporation during protein synthesis that can be used for in vivo labelling, cross-linking and protein-protein interaction studies in live cells.

Axiom
annotated source: pBpa-d11
annotated property: definition
annotated target: Deuterium labelled p-benzoyl-L-phenylalanine.
database_cross_reference: PMID:18704231

BS3
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
definition: Bis(sulfosuccinimidyl)suberate.
bridge formula: C8 H10 O2
mono isotopic mass: 138.06807961
reaction sites: 2
spacer length: 11.4
has_exact_synonym: BS3-H12
has_exact_synonym: BS3-d0
has_exact_synonym: BSSS
has_exact_synonym: Bis(sulfosuccinimidyl)suberate
has_exact_synonym: Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester)
has_exact_synonym: Sulfo-DSS
has_obo_namespace: XLMOD
id: XLMOD:02000

Axiom
annotated source: BS3
annotated property: definition
annotated target: Bis(sulfosuccinimidyl)suberate.
database_cross_reference: CAS:82436-77-9
database_cross_reference: ChemSpiderID:110394
database_cross_reference: ChemicalBookNo:CB0136444
database_cross_reference: PMID:12892908
database_cross_reference: PubChem_Compound:6097991

DSS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Disuccinimidyl suberate.
bridge formula: C8 H10 O2
mono isotopic mass: 138.06807961
reaction sites: 2
spacer length: 11.4
has_exact_synonym: 1,1'-[(1,8-Dioxooctane-1,8-diyl)bis(oxy)]dipyrrolidine-2,5-dione
has_exact_synonym: Bis(succinimidyl) suberate
has_exact_synonym: DSS-H12
has_exact_synonym: DSS-d0
has_exact_synonym: Disuccinimidyl octanedioate
has_exact_synonym: Suberic acid bis(N-hydroxysuccinimide ester)
has_obo_namespace: XLMOD
id: XLMOD:02001

Axiom
annotated source: DSS
annotated property: definition
annotated target: Disuccinimidyl suberate.
database_cross_reference: CAS:68528-80-3
database_cross_reference: ChemSpiderID:90944
database_cross_reference: ChemicalBookNo:CB1219157
database_cross_reference: PMID:16944939
database_cross_reference: PubChem_Compound:100658

DSS-d4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled disuccinimidyl 2,2,7,7-suberate.
bridge formula: C8 D4 H6 O2
doublet delta mass: 4.02508
mono isotopic mass: 142.093186586
reaction sites: 2
spacer length: 11.4
has_obo_namespace: XLMOD
id: XLMOD:02002

Axiom
annotated source: DSS-d4
annotated property: definition
annotated target: Deuterium labelled disuccinimidyl 2,2,7,7-suberate.
database_cross_reference: PMID:11354472
database_cross_reference: PubChem_Compound:91757798

DSS-d12
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled disuccinimidyl 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
bridge formula: C8 D10 O2
doublet delta mass: 12.07573
mono isotopic mass: 150.143400538
reaction sites: 2
spacer length: 11.4
has_obo_namespace: XLMOD
id: XLMOD:02003

Axiom
annotated source: DSS-d12
annotated property: definition
annotated target: Deuterium labelled disuccinimidyl 2,2,3,3,4,4,5,5,6,6,7,7-suberate.
database_cross_reference: PMID:11354472
database_cross_reference: PMID:16944939
database_cross_reference: PSI:XL

BS3-d4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled (bis(sulfosuccinimidyl) 2,2,7,7-suberate).
doublet delta mass: 4.02508
mono isotopic mass: 142.093186586
reaction sites: 2
spacer length: 11.4
has_obo_namespace: XLMOD
id: XLMOD:02004

Axiom
annotated source: BS3-d4
annotated property: definition
annotated target: Deuterium labelled (bis(sulfosuccinimidyl) 2,2,7,7-suberate).
database_cross_reference: PubChem_Compound:91757801

BS2G
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
definition: Bis(sulfosuccinimidyl) glutarate.
bridge formula: C5 H4 O2
mono isotopic mass: 96.0211294
reaction sites: 2
spacer length: 7.7
has_exact_synonym: BS2G-d0
has_exact_synonym: DSSG
has_exact_synonym: Disulfosuccinimidylglutarate
has_exact_synonym: Glutaric acid bis(3-sulfo-N-hydroxysuccinimide ester)
has_exact_synonym: Sulfo-DSG
has_obo_namespace: XLMOD
id: XLMOD:02005

Axiom
annotated source: BS2G
annotated property: definition
annotated target: Bis(sulfosuccinimidyl) glutarate.
database_cross_reference: ChemicalBookNo:CB91307211
database_cross_reference: PubChem_Compound:91757794

DSG
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Disuccinimidyl glutarate.
bridge formula: C5 H4 O2
mono isotopic mass: 96.0211294
reaction sites: 2
spacer length: 7.7
has_exact_synonym: Bis-NHS glutarate
has_exact_synonym: DSG-d0
has_exact_synonym: Di N-succinimidyl glutarate
has_exact_synonym: Di(N-succinimidyl) glutarate
has_exact_synonym: Di-succinimidyl glutarate
has_exact_synonym: Disuccinimidyl glutaric dicarboxylate
has_obo_namespace: XLMOD
id: XLMOD:02006

Axiom
annotated source: DSG
annotated property: definition
annotated target: Disuccinimidyl glutarate.
database_cross_reference: Beilstein:8575145
database_cross_reference: CAS:79642-50-5
database_cross_reference: ChemSpiderID:3632504
database_cross_reference: ChemicalBookNo:CB0373852
database_cross_reference: MDL:MFCD00153597
database_cross_reference: PubChem_Compound:4432628

DSG-d4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled disuccinimidyl 2,2,4,4-glutarate.
bridge formula: C5 D4 O2
doublet delta mass: 4.02508
mono isotopic mass: 100.046236376
reaction sites: 2
spacer length: 7.7
has_obo_namespace: XLMOD
id: XLMOD:02007

Axiom
annotated source: DSG-d4
annotated property: definition
annotated target: Deuterium labelled disuccinimidyl 2,2,4,4-glutarate.
database_cross_reference: PubChem_Compound:91757797

BS2G-d4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled bis(sulfosuccinimidyl) 2,2,4,4-glutarate.
bridge formula: C5 D4 O2
doublet delta mass: 4.02508
mono isotopic mass: 100.046236376
reaction sites: 2
spacer length: 7.7
has_exact_synonym: DSSG-d4
has_obo_namespace: XLMOD
id: XLMOD:02008

Axiom
annotated source: BS2G-d4
annotated property: definition
annotated target: Deuterium labelled bis(sulfosuccinimidyl) 2,2,4,4-glutarate.
database_cross_reference: PubChem_Compound:91757799

Disulfide
type: Class
subclass of: homofunctional cross-linker
subclass of: zero-length cross-linker
definition: Disulfide.
bridge formula: -H2
mono isotopic mass: -2.01565007
reaction sites: 2
specificities: (C)&(C)
stub formula: ETD = -H1 :
stub formula: ETD = -H1 : H1
stub formula: ETD = -H2 -S1 : S1
has_obo_namespace: XLMOD
id: XLMOD:02009

Axiom
annotated source: Disulfide
annotated property: definition
annotated target: Disulfide.
database_cross_reference: PSI:XL

1-ethyl-3-(3-Dimethylaminopropyl)carbodiimide hydrochloride
type: Class
subclass of: zero-length cross-linker
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: carbodiimide
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 1-ethyl-3-(3-Dimethylaminopropyl)carbodiimide hydrochloride.
bridge formula: -H2 -O1
mono isotopic mass: -18.01056027
reaction sites: 2
has_exact_synonym: 3-(3-Dimethylaminopropyl)-1-ethyl-carbodiimide hydrochloride
has_exact_synonym: EDAC-HCl
has_exact_synonym: EDC-HCl
has_exact_synonym: EDCI
has_obo_namespace: XLMOD
id: XLMOD:02010
comment: Used to conjugate carboxyl functional groups to primary amines from peptides and proteins and is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or nanoparticles.

Axiom
annotated source: 1-ethyl-3-(3-Dimethylaminopropyl)carbodiimide hydrochloride
annotated property: definition
annotated target: 1-ethyl-3-(3-Dimethylaminopropyl)carbodiimide hydrochloride.
database_cross_reference: Beilstein:5764110
database_cross_reference: CAS:25952-53-8
database_cross_reference: ChemSpiderID:2006116
database_cross_reference: ChemicalBookNo:CB7403031
database_cross_reference: MDL:MFCD00012503
database_cross_reference: PMID:19136724
database_cross_reference: PMID:3394930
database_cross_reference: PubChem_Compound:2723939

BDP-NHP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: N-hydroxyphthalimide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable by MS2 labile bond
definition: Biotin Aspartate Proline n-hydroxyphthalamide.
mono isotopic mass: 1241.469925525
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02011

Axiom
annotated source: BDP-NHP
annotated property: definition
annotated target: Biotin Aspartate Proline n-hydroxyphthalamide.
database_cross_reference: PSI:XL

ANB-NOS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
definition: N-5-Azido-2-nitrobenzoyloxysuccinimide.
reaction sites: 2
spacer length: 7.7
has_exact_synonym: 5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester
has_exact_synonym: N-(5-Azido-2-nitrobenzoyloxy)succinimide
has_exact_synonym: N-Succinimidyl 5-azido-2-nitrobenzoate
has_obo_namespace: XLMOD
id: XLMOD:02012

Axiom
annotated source: ANB-NOS
annotated property: definition
annotated target: N-5-Azido-2-nitrobenzoyloxysuccinimide.
database_cross_reference: Beilstein:1555224
database_cross_reference: CAS:60117-35-3
database_cross_reference: ChemSpiderID:2338587
database_cross_reference: ChemicalBookNo:CB7381289
database_cross_reference: MDL:MFCD00054962
database_cross_reference: PubChem_Compound:3080866

BMPS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-(beta-Maleimidopropyloxy)succinimide ester.
bridge formula: C7 H5 O3 N1
mono isotopic mass: 151.026943065
reaction sites: 2
spacer length: 6.9
has_exact_synonym: 3-Maleimidopropionic acid N-hydroxysuccinimide ester
has_exact_synonym: N-Succinimidyl 3-maleimidopropionate
has_obo_namespace: XLMOD
id: XLMOD:02013

Axiom
annotated source: BMPS
annotated property: definition
annotated target: N-(beta-Maleimidopropyloxy)succinimide ester.
database_cross_reference: Beilstein:1492578
database_cross_reference: CAS:55750-62-4
database_cross_reference: ChemSpiderID:3811455
database_cross_reference: ChemicalBookNo:CB5780592
database_cross_reference: MDL:MFCD00043141
database_cross_reference: PubChem_Compound:4620597

EMCS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 6-Maleimidohexanoic acid N-hydroxysuccinimide ester.
reaction sites: 2
spacer length: 9.4
has_exact_synonym: 6-maleimidohexanoic acid N-hydroxysuccinimide ester
has_exact_synonym: N-(epsilon-Malaimidocaproyloxy) succinimide ester
has_obo_namespace: XLMOD
id: XLMOD:02014

Axiom
annotated source: EMCS
annotated property: definition
annotated target: 6-Maleimidohexanoic acid N-hydroxysuccinimide ester.
database_cross_reference: CAS:55750-63-5
database_cross_reference: ChemSpiderID:4267588
database_cross_reference: ChemicalBookNo:CB8212960
database_cross_reference: PubChem_Compound:5091655

GMBS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-[gamma-Maleimidobutyryloxy] succinimide.
reaction sites: 2
spacer length: 7.3
has_exact_synonym: 4-Maleimdobutyric acid N-succinimidyl ester
has_obo_namespace: XLMOD
id: XLMOD:02015

Axiom
annotated source: GMBS
annotated property: definition
annotated target: N-[gamma-Maleimidobutyryloxy] succinimide.
database_cross_reference: CAS:80307-12-6
database_cross_reference: ChemSpiderID:117712
database_cross_reference: ChemicalBookNo:CB5267080
database_cross_reference: MDL:MFCD00036817
database_cross_reference: PubChem_Compound:133440

SPDP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: N-Succinimidyl 3-[2-pyridyldithio]-propionate.
reaction sites: 2
spacer length: 6.8
has_exact_synonym: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester
has_obo_namespace: XLMOD
id: XLMOD:02016

Axiom
annotated source: SPDP
annotated property: definition
annotated target: N-Succinimidyl 3-[2-pyridyldithio]-propionate.
database_cross_reference: CAS:68181-17-9
database_cross_reference: ChemSpiderID:90967
database_cross_reference: ChemicalBookNo:CB2446059
database_cross_reference: PubChem_Compound:100682

LC-SPDP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: Succinimidyl 6-(3-[2-pyridyldithio]-propionamido)hexanoate.
reaction sites: 2
spacer length: 15.7
has_exact_synonym: Long chain-SPDP
has_exact_synonym: Succinimidyl 6-(3-(2-Pyridyldithio)propionamido)hexanoate
has_obo_namespace: XLMOD
id: XLMOD:02017

Axiom
annotated source: LC-SPDP
annotated property: definition
annotated target: Succinimidyl 6-(3-[2-pyridyldithio]-propionamido)hexanoate.
database_cross_reference: CAS:158913-22-5
database_cross_reference: ChemSpiderID:138854
database_cross_reference: ChemicalBookNo:CB8355139
database_cross_reference: PubChem_Compound:157808

Sulfo-LC-SPDP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: Sulfosuccinimidyl 6-(3'-[2-pyridyldithio]-propionamido)hexanoate.
reaction sites: 2
spacer length: 15.7
has_exact_synonym: Sulfo-Long chain-SPDP
has_obo_namespace: XLMOD
id: XLMOD:02018

Axiom
annotated source: Sulfo-LC-SPDP
annotated property: definition
annotated target: Sulfosuccinimidyl 6-(3'-[2-pyridyldithio]-propionamido)hexanoate.
database_cross_reference: CAS:169751-10-4
database_cross_reference: ChemSpiderID:3780707
database_cross_reference: ChemicalBookNo:CB8177681
database_cross_reference: PubChem_Compound:4588467

MBS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: m-Maleimidobenzoyl-N-hydroxysuccinimide ester.
reaction sites: 2
spacer length: 7.3
has_exact_synonym: 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
has_exact_synonym: meta-Maleimidobenzoyl-N-hydroxysuccinimide ester
has_obo_namespace: XLMOD
id: XLMOD:02019

Axiom
annotated source: MBS
annotated property: definition
annotated target: m-Maleimidobenzoyl-N-hydroxysuccinimide ester.
database_cross_reference: CAS:58626-38-3
database_cross_reference: ChemSpiderID:84714
database_cross_reference: ChemicalBookNo:CB0342553
database_cross_reference: PubChem_Compound:93861

Sulfo-MBS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester.
reaction sites: 2
spacer length: 7.3
has_exact_synonym: 3-Maleimidobenzoic acid N-hydroxysulfosuccinimide ester
has_exact_synonym: meta-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester
has_obo_namespace: XLMOD
id: XLMOD:02020

Axiom
annotated source: Sulfo-MBS
annotated property: definition
annotated target: m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester.
database_cross_reference: CAS:92921-25-0
database_cross_reference: ChemSpiderID:111159
database_cross_reference: ChemicalBookNo:CB9338287

PDPH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: 3-[2-Pyridyldithio]propionyl hydrazide.
reaction sites: 2
spacer length: 9.2
has_exact_synonym: 3-(2-pyridyldithio)propionyl hydrazide
has_exact_synonym: S-(2-thiopyridyl)-3-mercaptopropionic acid hydrazide
has_exact_synonym: SPDP Hydrazide
has_exact_synonym: TPMPH
has_obo_namespace: XLMOD
id: XLMOD:02021

Axiom
annotated source: PDPH
annotated property: definition
annotated target: 3-[2-Pyridyldithio]propionyl hydrazide.
database_cross_reference: CAS:115616-51-8
database_cross_reference: ChemSpiderID:115670
database_cross_reference: ChemicalBookNo:CB3412468
database_cross_reference: PubChem_Compound:130785

SBA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: bromoacetyl
definition: N-Succinimidyl bromoacetate.
reaction sites: 2
spacer length: 1.5
has_exact_synonym: Bromoacetic acid N-hydroxysuccinimide ester
has_exact_synonym: NHS-Bromoacetate
has_exact_synonym: SIB
has_exact_synonym: Succinimidyl bromoacetate
has_obo_namespace: XLMOD
id: XLMOD:02022

Axiom
annotated source: SBA
annotated property: definition
annotated target: N-Succinimidyl bromoacetate.
database_cross_reference: CAS:42014-51-7
database_cross_reference: ChemSpiderID:2802588
database_cross_reference: ChemicalBookNo:CB4678610
database_cross_reference: PubChem_Compound:3565210

SIA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: iodoacetyl
definition: N-Succinimidyl iodoacetate.
reaction sites: 2
spacer length: 1.5
has_exact_synonym: Iodoacetic acid N-hydroxysuccinimide ester
has_exact_synonym: NHS-Iodoacetate
has_exact_synonym: Succinimidyl iodoacetate
has_obo_namespace: XLMOD
id: XLMOD:02023

Axiom
annotated source: SIA
annotated property: definition
annotated target: N-Succinimidyl iodoacetate.
database_cross_reference: CAS:39028-27-8
database_cross_reference: ChemSpiderID:2547635
database_cross_reference: ChemicalBookNo:CB9364435
database_cross_reference: PubChem_Compound:3299230

SMCC
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate.
reaction sites: 2
spacer length: 11.6
has_exact_synonym: 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester
has_exact_synonym: N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate
has_exact_synonym: Succinimidyl trans-4-(N-maleimidylmethyl)cyclohexane-1-carboxylate
has_obo_namespace: XLMOD
id: XLMOD:02024

Axiom
annotated source: SMCC
annotated property: definition
annotated target: Succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate.
database_cross_reference: CAS:64987-85-5
database_cross_reference: ChemSpiderID:21173480
database_cross_reference: ChemicalBookNo:CB6748487
database_cross_reference: PubChem_Compound:125175

Sulfo-SMCC
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate.
reaction sites: 2
spacer length: 11.6
has_exact_synonym: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester
has_exact_synonym: S-SMCC
has_exact_synonym: SSMCC
has_exact_synonym: Sulfosuccinimidyl-4-N-maleimidomethyl-cyclohexane-1-carboxylate
has_obo_namespace: XLMOD
id: XLMOD:02025

Axiom
annotated source: Sulfo-SMCC
annotated property: definition
annotated target: Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate.
database_cross_reference: CAS:92921-24-9
database_cross_reference: ChemSpiderID:3809728
database_cross_reference: ChemicalBookNo:CB6219112
database_cross_reference: PubChem_Compound:16219679

SMPB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-Succinimidyl 4-[4-maleimidophenyl]butyrate.
reaction sites: 2
spacer length: 11.6
has_exact_synonym: 4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester
has_obo_namespace: XLMOD
id: XLMOD:02026

Axiom
annotated source: SMPB
annotated property: definition
annotated target: N-Succinimidyl 4-[4-maleimidophenyl]butyrate.
database_cross_reference: CAS:79886-55-8
database_cross_reference: ChemSpiderID:90966
database_cross_reference: ChemicalBookNo:CB3322684
database_cross_reference: PubChem_Compound:100681

SMPH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: is_cleavable
  some values from: thiol cleavable
definition: Succinimidyl-6-[beta-maleimidopropionamido]hexanoate.
reaction sites: 2
spacer length: 14.3
has_exact_synonym: Succinimidyl 6-[(3-maleimido)propionamido]-hexanoate
has_obo_namespace: XLMOD
id: XLMOD:02027

Axiom
annotated source: SMPH
annotated property: definition
annotated target: Succinimidyl-6-[beta-maleimidopropionamido]hexanoate.
database_cross_reference: CAS:367927-39-7
database_cross_reference: ChemSpiderID:3381798
database_cross_reference: ChemicalBookNo:CB2100210
database_cross_reference: PubChem_Compound:4170355

Sulfo-SANPAH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
definition: N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate.
reaction sites: 2
spacer length: 18.2
has_exact_synonym: 1-[6-[(4-azido-2-nitro-phenyl)amino]hexanoyloxy]-2,5-Dioxo-pyrrolidine-3-sulfonic acid
has_exact_synonym: Sulfosuccinimidyl 6-((4'-azido-2'-nitrophenyl)amino)hexanoate
has_exact_synonym: Sulfosuccinimidyl 6-((4-azido-2-nitrophenyl)amino)hexanoate
has_obo_namespace: XLMOD
id: XLMOD:02028

Axiom
annotated source: Sulfo-SANPAH
annotated property: definition
annotated target: N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate.
database_cross_reference: CAS:102568-43-4
database_cross_reference: ChemSpiderID:2300000
database_cross_reference: ChemicalBookNo:CB4457477
database_cross_reference: PubChem_Compound:3035866

DSP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Dithiobis[succinimidyl propionate.
bridge formula: C6 H6 O2 S2
mono isotopic mass: 173.98092087
reaction sites: 2
spacer length: 12.0
has_exact_synonym: 3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester)
has_exact_synonym: DSP-d0
has_exact_synonym: DTSP
has_exact_synonym: Di(N-succinimidyl) 3,3'-Dithiodipropionate
has_exact_synonym: Dithio-bis-succinimidyl propionate
has_exact_synonym: Dithiobis(succinimidyl propionate)
has_exact_synonym: Dithiobis-succinimidyl propionate
has_exact_synonym: Lomant's Reagent
has_obo_namespace: XLMOD
id: XLMOD:02029

Axiom
annotated source: DSP
annotated property: definition
annotated target: Dithiobis[succinimidyl propionate.
database_cross_reference: Beilstein:1518074
database_cross_reference: CAS:57757-57-0
database_cross_reference: ChemSpiderID:84243
database_cross_reference: ChemicalBookNo:CB7251791
database_cross_reference: MDL:MFCD00042045
database_cross_reference: PubChem_Compound:93313

DSP-d8
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled Dithiobis[1,1,2,2,2,2,3,3-succinimidyl propionate.
bridge formula: C6 D6 O2 S2
doublet delta mass: 8.05016
mono isotopic mass: 182.0314167
reaction sites: 2
spacer length: 12.0
has_obo_namespace: XLMOD
id: XLMOD:02030

Axiom
annotated source: DSP-d8
annotated property: definition
annotated target: Deuterium labelled Dithiobis[1,1,2,2,2,2,3,3-succinimidyl propionate.
database_cross_reference: PubChem_Compound:91757796

DSSeb
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Sebacic acid bis[N-hydroxysuccinimide ester].
reaction sites: 2
spacer length: 14.1
has_exact_synonym: Di(N-succinimidyl) sebacate
has_exact_synonym: Disuccinimidyl sebacate
has_exact_synonym: Sebacic acid bis(N-hydroxysuccinimide ester)
has_obo_namespace: XLMOD
id: XLMOD:02031

Axiom
annotated source: DSSeb
annotated property: definition
annotated target: Sebacic acid bis[N-hydroxysuccinimide ester].
database_cross_reference: CAS:23024-29-5
database_cross_reference: ChemSpiderID:2674029
database_cross_reference: ChemicalBookNo:CB4402699
database_cross_reference: PubChem_Compound:3430836

DST
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: periodate cleavable
definition: Disuccinimidyl tartrate.
bridge formula: C4 H2 O4
mono isotopic mass: 113.99531
reaction sites: 2
spacer length: 6.4
has_exact_synonym: Disuccinimidyl L-Tartrate
has_obo_namespace: XLMOD
id: XLMOD:02032

Axiom
annotated source: DST
annotated property: definition
annotated target: Disuccinimidyl tartrate.
database_cross_reference: CAS:62069-75-4
database_cross_reference: ChemSpiderID:296442
database_cross_reference: ChemicalBookNo:CB9243998
database_cross_reference: MDL:MFCD03788224
database_cross_reference: PubChem_Compound:124912

DTSSP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: 3,3'-Dithiobis[sulfosuccinimidylpropionate].
bridge formula: C6 H6 O2 S2
mono isotopic mass: 173.98093
reaction sites: 2
spacer length: 12.0
has_exact_synonym: 3,3'-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester
has_exact_synonym: DTBSSP
has_exact_synonym: DTSSP-d0
has_exact_synonym: Sulfo-DSP
has_exact_synonym: Sulfo-DTSP
has_obo_namespace: XLMOD
id: XLMOD:02033

Axiom
annotated source: DTSSP
annotated property: definition
annotated target: 3,3'-Dithiobis[sulfosuccinimidylpropionate].
database_cross_reference: CAS:81069-02-5
database_cross_reference: ChemSpiderID:110462
database_cross_reference: ChemicalBookNo:CB31073260
database_cross_reference: MDL:MFCD01861949
database_cross_reference: PMID:10975572
database_cross_reference: PMID:18510349
database_cross_reference: PubChem_Compound:123933

EGS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: hydroxylamine cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: ammonium cleavable
definition: Ethylene glycolbis(succinimidylsuccinate).
bridge formula: C10 H10 O6
mono isotopic mass: 226.047738
reaction sites: 2
spacer length: 16.1
has_exact_synonym: EGS-d0
has_exact_synonym: Ethylene Glycol-Bis (Succinic Acid N-Hydroxysuccinimide Ester)
has_exact_synonym: Ethylene glycol bis (succinimidylsuccinate)
has_obo_namespace: XLMOD
id: XLMOD:02034

Axiom
annotated source: EGS
annotated property: definition
annotated target: Ethylene glycolbis(succinimidylsuccinate).
database_cross_reference: CAS:70539-42-3
database_cross_reference: ChemSpiderID:110243
database_cross_reference: ChemicalBookNo:CB5722624
database_cross_reference: PubChem_Compound:123663

Sulfo-EGS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: hydroxylamine cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: ammonium cleavable
definition: Ethylene glycolbis(sulfosuccinimidylsuccinate).
bridge formula: C10 H10 O6
mono isotopic mass: 226.04774
reaction sites: 2
spacer length: 16.1
has_exact_synonym: Bis(sulfo-N-succinimidyl) ethylene glycol disuccinate
has_exact_synonym: EGSS
has_exact_synonym: EGSS-d0
has_exact_synonym: Ethylene Glycol-Bis (Succinic Acid N-Hydroxysulfosuccinimide Ester)
has_exact_synonym: Ethylene glycol bis(sulfosuccinimidylsuccinate)
has_exact_synonym: Ethylene glycol disuccinate bis(sulfo-N-succinimidyl) ester
has_obo_namespace: XLMOD
id: XLMOD:02035

Axiom
annotated source: Sulfo-EGS
annotated property: definition
annotated target: Ethylene glycolbis(sulfosuccinimidylsuccinate).
database_cross_reference: CAS:167410-92-6
database_cross_reference: ChemSpiderID:32034171
database_cross_reference: ChemicalBookNo:CB4497176
database_cross_reference: PubChem_Compound:91757793

CDI
type: Class
subclass of: zero-length cross-linker
definition: N,N'-Carbonyldiimidazole.
reaction sites: 2
has_exact_synonym: 1,1'-Carbonyldiimidazole
has_obo_namespace: XLMOD
id: XLMOD:02036
comment: Used to convert alcohols and amines into carbamates, esters, and ureas.

Axiom
annotated source: CDI
annotated property: definition
annotated target: N,N'-Carbonyldiimidazole.
database_cross_reference: Beilstein:6826
database_cross_reference: CAS:530-62-1
database_cross_reference: ChemSpiderID:61561
database_cross_reference: ChemicalBookNo:CB0215374
database_cross_reference: MDL:MFCD00005286
database_cross_reference: PubChem_Compound:68263

DCC
type: Class
subclass of: zero-length cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: carbodiimide
definition: N,N'-Dicyclohexylcarbodiimide.
reaction sites: 2
has_exact_synonym: 1,3-Dicyclohexylcarbodiimide
has_exact_synonym: Bis(cyclohexyl)carbodiimide
has_exact_synonym: Cyclohexaamine, N,N'-methanetetraylbis-(9CI)
has_exact_synonym: DCCD
has_exact_synonym: DCCI
has_exact_synonym: Dicyclohexylcarbodiimide
has_exact_synonym: N,N'-Dicyclohexylcarbodiimide
has_exact_synonym: N,N'-Methanetetrayl biscyclohexanamine
has_obo_namespace: XLMOD
id: XLMOD:02037
comment: Used for coupling amines and carboxylates without the insertion of spacer atoms.

Axiom
annotated source: DCC
annotated property: definition
annotated target: N,N'-Dicyclohexylcarbodiimide.
database_cross_reference: Beilstein:610662
database_cross_reference: CAS:538-75-0
database_cross_reference: ChemSpiderID:10408
database_cross_reference: ChemicalBookNo:CB9706578
database_cross_reference: MDL:MFCD00011659
database_cross_reference: PubChem_Compound:10868

NHS
type: Class
subclass of: zero-length cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
definition: N-hydroxysuccinimide.
has_exact_synonym: 1-Hydroxy-2,5-pyrrolidinedione
has_obo_namespace: XLMOD
id: XLMOD:02038
comment: Used in conjunction with EDC-HCl (EDAC-HCl) to convert carboxyl groups to NHS esters which react with primary amines.

Axiom
annotated source: NHS
annotated property: definition
annotated target: N-hydroxysuccinimide.
database_cross_reference: Beilstein:113913
database_cross_reference: CAS:6066-82-6
database_cross_reference: ChemSpiderID:72416
database_cross_reference: ChemicalBookNo:CB0391283
database_cross_reference: MDL:MFCD00005516
database_cross_reference: PubChem_Compound:80170

Sulfo-NHS
type: Class
subclass of: zero-length cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
definition: N-hydroxysulfosuccinimide.
has_exact_synonym: Hydroxy-2,5-Dioxopyrrolidine-3-sulfonicacid
has_exact_synonym: S-NHS
has_exact_synonym: Sulfo NHS
has_obo_namespace: XLMOD
id: XLMOD:02039
comment: Used in conjunction with EDC-HCl (EDAC-HCl) to convert carboxyl groups to Sulfo-NHS esters which react with primary amines.

Axiom
annotated source: Sulfo-NHS
annotated property: definition
annotated target: N-hydroxysulfosuccinimide.
database_cross_reference: CAS:106627-54-7
database_cross_reference: ChemSpiderID:2759874
database_cross_reference: ChemicalBookNo:CB9164497
database_cross_reference: MDL:MFCD00043100
database_cross_reference: PubChem_Compound:3520574

BiPS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: photo cleavable
definition: Bimane bisthiopropionic acid N-succinimidyl ester.
bridge formula: C16 H16 N2 O4 S2
mono isotopic mass: 364.05515
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02040

Axiom
annotated source: BiPS
annotated property: definition
annotated target: Bimane bisthiopropionic acid N-succinimidyl ester.
database_cross_reference: PMID:18838738

formaldehyde
type: Class
subclass of: homofunctional cross-linker
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: aldehyde group
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: Formaldehyde reagent.
reaction sites: 1
spacer length: 2.5
has_obo_namespace: XLMOD
id: XLMOD:02041

Axiom
annotated source: formaldehyde
annotated property: definition
annotated target: Formaldehyde reagent.
database_cross_reference: CAS:50-00-0
database_cross_reference: ChemSpiderID:692
database_cross_reference: ChemicalBookNo:CB4853677
database_cross_reference: PMID:18438963
database_cross_reference: PMID:25979347

glutardialdehyde
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: aldehyde group
subclass of: Restriction
  on property: is_reactive_with
  some values from: non-selective
definition: Glutardialdehyde.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02042

Axiom
annotated source: glutardialdehyde
annotated property: definition
annotated target: Glutardialdehyde.
database_cross_reference: CAS:111-30-8
database_cross_reference: ChemSpiderID:3365
database_cross_reference: ChemicalBookNo:CB3762723

DSA
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Disuccinimidyladipic acid.
bridge formula: C6 H6 O2
mono isotopic mass: 110.03624
reaction sites: 2
has_exact_synonym: disuccinimidyl adipate
has_obo_namespace: XLMOD
id: XLMOD:02043

Axiom
annotated source: DSA
annotated property: definition
annotated target: Disuccinimidyladipic acid.
database_cross_reference: CAS:26544-38-7
database_cross_reference: ChemSpiderID:4515188
database_cross_reference: ChemicalBookNo:CB5470426
database_cross_reference: PubChem_Compound:6438029

DNBDPS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: DNB
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: An isotopically-coded cleavable crosslinker affinity-purifyable with antibodies.
bridge formula: C12 H9 N2 O6 S2
mono isotopic mass: 339.98238
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02044

Axiom
annotated source: DNBDPS
annotated property: definition
annotated target: An isotopically-coded cleavable crosslinker affinity-purifyable with antibodies.
database_cross_reference: PMID:20109223

TEABS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: is_cleavable
  some values from: DTT cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: ammonium cleavable
definition: TEABS cross-linking reagent.
bridge formula: C28 H39 N5 O11 S1
mono isotopic mass: 653.23668
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02045

Axiom
annotated source: TEABS
annotated property: definition
annotated target: TEABS cross-linking reagent.
database_cross_reference: PMID:20109223

CLIP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: alkyne
subclass of: Restriction
  on property: has_neutral_loss_reporter
  some values from: NO2 neutral loss reporter
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Click-enabled linker for interacting proteins.
reaction sites: 2
spacer length: 9.5
has_obo_namespace: XLMOD
id: XLMOD:02046

Axiom
annotated source: CLIP
annotated property: definition
annotated target: Click-enabled linker for interacting proteins.
database_cross_reference: PMID:19496583

BDRG
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: pentafluorophenyl
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable by MS2 labile bond
definition: Biotin-aspartate-Rink-glycine cross-linker composed of a biotin affinity handle (B), a pentafluorophenyl (PFP) ester modified aspartate reside (D), a Rink group (R), and a PFP ester modified glycine reside (G).
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02047

Axiom
annotated source: BDRG
annotated property: definition
annotated target: Biotin-aspartate-Rink-glycine cross-linker composed of a biotin affinity handle (B), a pentafluorophenyl (PFP) ester modified aspartate reside (D), a Rink group (R), and a PFP ester modified glycine reside (G).
database_cross_reference: PMID:22067100

DTSSP-d8
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled 3,3'-Dithiobis[sulfosuccinimidylpropionate].
bridge formula: C6 D6 O2 S2
doublet delta mass: 8.05016
mono isotopic mass: 182.03109
reaction sites: 2
spacer length: 12.0
has_obo_namespace: XLMOD
id: XLMOD:02048

Axiom
annotated source: DTSSP-d8
annotated property: definition
annotated target: Deuterium labelled 3,3'-Dithiobis[sulfosuccinimidylpropionate].
database_cross_reference: PMID:10975572
database_cross_reference: PMID:18510349

EGS-d12
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: hydroxylamine cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: ammonium cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled ethylene glycolbis(succinimidylsuccinate).
bridge formula: C10 D10 O6
doublet delta mass: 12.07573
mono isotopic mass: 238.12347
reaction sites: 2
spacer length: 16.1
has_obo_namespace: XLMOD
id: XLMOD:02049

Axiom
annotated source: EGS-d12
annotated property: definition
annotated target: Deuterium labelled ethylene glycolbis(succinimidylsuccinate).
database_cross_reference: PMID:15901824

Sulfo-EGS-d12
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: hydroxylamine cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: ammonium cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled ethylene glycolbis(sulfosuccinimidylsuccinate).
bridge formula: C10 D10 O6
doublet delta mass: 12.07573
mono isotopic mass: 238.12347
reaction sites: 2
spacer length: 16.1
has_obo_namespace: XLMOD
id: XLMOD:02050

Axiom
annotated source: Sulfo-EGS-d12
annotated property: definition
annotated target: Deuterium labelled ethylene glycolbis(sulfosuccinimidylsuccinate).
database_cross_reference: PMID:15901824

PCAS
type: Class
subclass of: homofunctional cross-linker
definition: Pyridine-3-Carboxylic Acid Succinimide.
bridge formula: C6 H3 N1 O1
mono isotopic mass: 105.02146
reaction sites: 2
has_exact_synonym: PCAS-H4
has_exact_synonym: PCAS-d0
has_exact_synonym: PCASS
has_obo_namespace: XLMOD
id: XLMOD:02051

Axiom
annotated source: PCAS
annotated property: definition
annotated target: Pyridine-3-Carboxylic Acid Succinimide.
database_cross_reference: PMID:20050626
database_cross_reference: PMID:23085224

PCAS-d4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Pyridine-3-Carboxylic Acid Succinimide.
bridge formula: C6 D3 N1 O1
doublet delta mass: 4.02508
mono isotopic mass: 109.04812
reaction sites: 2
has_exact_synonym: PCASS-d4
has_obo_namespace: XLMOD
id: XLMOD:02052

Axiom
annotated source: PCAS-d4
annotated property: definition
annotated target: Pyridine-3-Carboxylic Acid Succinimide.
database_cross_reference: PMID:20050626
database_cross_reference: PMID:23085224

DSA-13C6
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
definition: 13C labelled disuccinimidyladipic acid.
bridge formula: 13C6 H6 O2
doublet delta mass: 6.02016
mono isotopic mass: 116.0564
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02053

Axiom
annotated source: DSA-13C6
annotated property: definition
annotated target: 13C labelled disuccinimidyladipic acid.
database_cross_reference: PSI:XL

CBDPS-d8
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled cyanurbiotindipropionylsuccinimide.
bridge formula: C19 D8 H15 N7 O4 S3
doublet delta mass: 8.05016
mono isotopic mass: 517.14698
reaction sites: 2
spacer length: 14.0
has_obo_namespace: XLMOD
id: XLMOD:02054

Axiom
annotated source: CBDPS-d8
annotated property: definition
annotated target: Deuterium labelled cyanurbiotindipropionylsuccinimide.
database_cross_reference: PMID:20622150

CBDPSS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Cyanurbiotindimercaptopropionylsulfosuccinimide.
bridge formula: C19 H23 N7 O4 S3
mono isotopic mass: 509.09682
reaction sites: 2
spacer length: 14.0
has_exact_synonym: Sulfo-CBDPSS
has_obo_namespace: XLMOD
id: XLMOD:02055

Axiom
annotated source: CBDPSS
annotated property: definition
annotated target: Cyanurbiotindimercaptopropionylsulfosuccinimide.
database_cross_reference: PMID:20622150

CBDPSS-d8
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled cyanurbiotindimercaptopropionylsulfosuccinimide.
bridge formula: C19 D8 H15 N7 O4 S3
doublet delta mass: 8.05016
mono isotopic mass: 517.14698
reaction sites: 2
spacer length: 14.0
has_obo_namespace: XLMOD
id: XLMOD:02056

Axiom
annotated source: CBDPSS-d8
annotated property: definition
annotated target: Deuterium labelled cyanurbiotindimercaptopropionylsulfosuccinimide.
database_cross_reference: PMID:20622150

SDH
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Suberic acid 1,8-dihydrazide.
bridge formula: C8 H14 N4
mono isotopic mass: 166.12184649
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02057

Axiom
annotated source: SDH
annotated property: definition
annotated target: Suberic acid 1,8-dihydrazide.
database_cross_reference: CAS:20247-84-1
database_cross_reference: ChemSpiderID:520361
database_cross_reference: ChemicalBookNo:CB8664268
database_cross_reference: PMID:24938783

SDH-d12
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled suberic acid 1,8-dihydrazide.
bridge formula: C8 D12 H2 N4
doublet delta mass: 12.07573
mono isotopic mass: 178.1971667418
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02058

Axiom
annotated source: SDH-d12
annotated property: definition
annotated target: Deuterium labelled suberic acid 1,8-dihydrazide.
database_cross_reference: PMID:24938783

ADH
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Adipic acid 1,6-dihydrazide.
bridge formula: C6 H10 N4
mono isotopic mass: 138.09054635
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02059

Axiom
annotated source: ADH
annotated property: definition
annotated target: Adipic acid 1,6-dihydrazide.
database_cross_reference: CAS:1071-93-8
database_cross_reference: ChemSpiderID:59505
database_cross_reference: ChemicalBookNo:CB4129556
database_cross_reference: PMID:24938783

ADH-d8
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled adipic acid 1,6-dihydrazide.
bridge formula: C6 D8 H2 N4
doublet delta mass: 8.05016
mono isotopic mass: 146.140760302
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02060

Axiom
annotated source: ADH-d8
annotated property: definition
annotated target: Deuterium labelled adipic acid 1,6-dihydrazide.
database_cross_reference: PMID:24938783

GDH
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Glutaric acid 1,5-dihydrazide.
bridge formula: C5 H8 N4
mono isotopic mass: 124.07489628
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02061

Axiom
annotated source: GDH
annotated property: definition
annotated target: Glutaric acid 1,5-dihydrazide.
database_cross_reference: CAS:1508-67-4
database_cross_reference: ChemSpiderID:3179469
database_cross_reference: ChemicalBookNo:CB4453510
database_cross_reference: PMID:24938783

GDH-d6
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled glutaric acid 1,5-dihydrazide.
bridge formula: C5 D6 H2 N4
doublet delta mass: 6.04368
mono isotopic mass: 130.112556744
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02062

Axiom
annotated source: GDH-d6
annotated property: definition
annotated target: Deuterium labelled glutaric acid 1,5-dihydrazide.
database_cross_reference: PMID:24938783

BS3-d12
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled (bis(sulfosuccinimidyl) 2,2,3,3,4,4,5,5,6,6,7,7-suberate).
doublet delta mass: 12.07573
mono isotopic mass: 150.14381
reaction sites: 2
spacer length: 11.4
has_obo_namespace: XLMOD
id: XLMOD:02063

Axiom
annotated source: BS3-d12
annotated property: definition
annotated target: Deuterium labelled (bis(sulfosuccinimidyl) 2,2,3,3,4,4,5,5,6,6,7,7-suberate).
database_cross_reference: PSI:XL

DSG-d6
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled disuccinimidyl 2,2,3,3,4,4-glutarate.
bridge formula: C5 D6 O2
doublet delta mass: 6.02016
mono isotopic mass: 102.05821
reaction sites: 2
spacer length: 7.7
has_obo_namespace: XLMOD
id: XLMOD:02064

Axiom
annotated source: DSG-d6
annotated property: definition
annotated target: Deuterium labelled disuccinimidyl 2,2,3,3,4,4-glutarate.
database_cross_reference: PSI:XL

BS2G-d6
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled bis(sulfosuccinimidyl) 2,2,3,3,4,4-glutarate.
bridge formula: C5 D4 O2
doublet delta mass: 4.02508
mono isotopic mass: 100.046236376
reaction sites: 2
spacer length: 7.7
has_exact_synonym: DSSG-d6
has_obo_namespace: XLMOD
id: XLMOD:02065

Axiom
annotated source: BS2G-d6
annotated property: definition
annotated target: Deuterium labelled bis(sulfosuccinimidyl) 2,2,3,3,4,4-glutarate.
database_cross_reference: PSI:XL

SATA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: S-acetyl
subclass of: Restriction
  on property: is_cleavable
  some values from: hydroxylamine cleavable
definition: Succinimidyl acetylthioacetate.
reaction sites: 2
spacer length: 2.8
has_exact_synonym: N-succinimidyl S-acetylthioacetate
has_obo_namespace: XLMOD
id: XLMOD:02066

Axiom
annotated source: SATA
annotated property: definition
annotated target: Succinimidyl acetylthioacetate.
database_cross_reference: CAS:76931-93-6
database_cross_reference: ChemSpiderID:113145
database_cross_reference: ChemicalBookNo:CB6378192
database_cross_reference: PubChem_Compound:127532

SATP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: S-acetyl
subclass of: Restriction
  on property: is_cleavable
  some values from: hydroxylamine cleavable
definition: N-succinimidyl-S-acetylthiopropionate.
reaction sites: 2
spacer length: 4.1
has_obo_namespace: XLMOD
id: XLMOD:02067

Axiom
annotated source: SATP
annotated property: definition
annotated target: N-succinimidyl-S-acetylthiopropionate.
database_cross_reference: CAS:84271-78-3
database_cross_reference: ChemSpiderID:3324023
database_cross_reference: ChemicalBookNo:CB7151156
database_cross_reference: PubChem_Compound:4110341

LC-SMCC
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate).
reaction sites: 2
spacer length: 16.2
has_exact_synonym: Long chain-SMCC
has_obo_namespace: XLMOD
id: XLMOD:02068

Axiom
annotated source: LC-SMCC
annotated property: definition
annotated target: Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate).
database_cross_reference: CAS:125559-00-4
database_cross_reference: ChemSpiderID:2802130
database_cross_reference: ChemicalBookNo:CB2681973
database_cross_reference: PubChem_Compound:3564731

PEAS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl azide
definition: N-((2-pyridyldithio)ethyl)-4-azidosalicylamide.
reaction sites: 2
has_exact_synonym: AES
has_obo_namespace: XLMOD
id: XLMOD:02069

Axiom
annotated source: PEAS
annotated property: definition
annotated target: N-((2-pyridyldithio)ethyl)-4-azidosalicylamide.
database_cross_reference: MDL:MFCD00467787
database_cross_reference: PMID:11320237

BisEA
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: Bis-(2-(Methanethiosulfonato)ethyl)amine.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02070

Axiom
annotated source: BisEA
annotated property: definition
annotated target: Bis-(2-(Methanethiosulfonato)ethyl)amine.
database_cross_reference: PSI:XL

3,6,9,12-Tetraoxatetradecane-1,14-diyl dimethanethiosulfonate
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 3,6,9,12-Tetraoxatetradecane-1,14-diyl dimethanethiosulfonate cross-linker.
reaction sites: 2
has_exact_synonym: 3,6,9,12-Tetraoxatetradecane-1,14-diyl-bis-methanethiosulfonate
has_obo_namespace: XLMOD
id: XLMOD:02071

Axiom
annotated source: 3,6,9,12-Tetraoxatetradecane-1,14-diyl dimethanethiosulfonate
annotated property: definition
annotated target: 3,6,9,12-Tetraoxatetradecane-1,14-diyl dimethanethiosulfonate cross-linker.
database_cross_reference: CAS:212262-08-3
database_cross_reference: ChemSpiderID:3765062
database_cross_reference: ChemicalBookNo:CB4773508
database_cross_reference: PubChem_Compound:46783053

3,6,9-Trioxaundecane-1,11-diyl dimethanethiosulfonate
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 3,6,9-Trioxaundecane-1,11-diyl dimethanethiosulfonate cross-linker.
reaction sites: 2
has_exact_synonym: 3,6,9-Trioxaundecane-1,11-diyl-bismethanethiosulfonate
has_obo_namespace: XLMOD
id: XLMOD:02072

Axiom
annotated source: 3,6,9-Trioxaundecane-1,11-diyl dimethanethiosulfonate
annotated property: definition
annotated target: 3,6,9-Trioxaundecane-1,11-diyl dimethanethiosulfonate cross-linker.
database_cross_reference: CAS:212262-02-7
database_cross_reference: ChemSpiderID:57565984
database_cross_reference: ChemicalBookNo:CB41175710
database_cross_reference: PubChem_Compound:5047788

MTS-1-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 1,1-Methanediyl Bismethanethiosulfonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02073

Axiom
annotated source: MTS-1-MTS
annotated property: definition
annotated target: 1,1-Methanediyl Bismethanethiosulfonate.
database_cross_reference: CAS:22418-52-6
database_cross_reference: ChemSpiderID:3459853
database_cross_reference: ChemicalBookNo:CB01175439
database_cross_reference: PubChem_Compound:4251850

MTS-2-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 1,2-Ethanediyl Bismethanethiosulfonate.
reaction sites: 2
has_exact_synonym: 1,2-Ethanedithiol Dimethanesulfonate
has_exact_synonym: Preparation 289
has_obo_namespace: XLMOD
id: XLMOD:02074

Axiom
annotated source: MTS-2-MTS
annotated property: definition
annotated target: 1,2-Ethanediyl Bismethanethiosulfonate.
database_cross_reference: CAS:55-95-8
database_cross_reference: ChemSpiderID:490602
database_cross_reference: ChemicalBookNo:CB31175450
database_cross_reference: MDL:MFCD01320400
database_cross_reference: PubChem_Compound:564320

MTS-6-NHS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: N-Succinimidyloxycarbonylpentyl methanethiosulfonate.
reaction sites: 2
has_exact_synonym: 6-[(Methanethisulfonyl)thio]hexanoic acid, N-succinimidyl ester
has_obo_namespace: XLMOD
id: XLMOD:02075

Axiom
annotated source: MTS-6-NHS
annotated property: definition
annotated target: N-Succinimidyloxycarbonylpentyl methanethiosulfonate.
database_cross_reference: CAS:76078-81-4
database_cross_reference: ChemSpiderID:2849984
database_cross_reference: ChemicalBookNo:CB6747738
database_cross_reference: PubChem_Compound:3614736

MTS-8-O2-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 3,6-dioxaoctane-1,8-diyl dimethanethiosulfonate.
reaction sites: 2
has_exact_synonym: 1,2-bis(2-methylsulfonylsulfanylethoxy)ethane
has_exact_synonym: 3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate
has_obo_namespace: XLMOD
id: XLMOD:02076

Axiom
annotated source: MTS-8-O2-MTS
annotated property: definition
annotated target: 3,6-dioxaoctane-1,8-diyl dimethanethiosulfonate.
database_cross_reference: CAS:212262-04-9
database_cross_reference: ChemSpiderID:2579076
database_cross_reference: ChemicalBookNo:CB01175712
database_cross_reference: PubChem_Compound:3332000

MTS-11-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: Undecane-1,11-diyl-bismethanethiosulfonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02077

Axiom
annotated source: MTS-11-MTS
annotated property: definition
annotated target: Undecane-1,11-diyl-bismethanethiosulfonate.
database_cross_reference: PSI:XL

BSOCOES
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: base cleavable
definition: Bis(2-[Succinimidooxycarbonyloxy]ethyl) sulfone.
bridge formula: C6 H6 O6 S1
mono isotopic mass: 205.988512
reaction sites: 2
spacer length: 13.0
has_obo_namespace: XLMOD
id: XLMOD:02078

Axiom
annotated source: BSOCOES
annotated property: definition
annotated target: Bis(2-[Succinimidooxycarbonyloxy]ethyl) sulfone.
database_cross_reference: CAS:57683-72-4
database_cross_reference: ChemSpiderID:84638
database_cross_reference: ChemicalBookNo:CB6488705
database_cross_reference: PubChem_Compound:93771

DPDPB
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: 1,4-Di-(3'-[2'pyridyldithio]-propionamido) butane.
reaction sites: 2
spacer length: 19.9
has_obo_namespace: XLMOD
id: XLMOD:02079

Axiom
annotated source: DPDPB
annotated property: definition
annotated target: 1,4-Di-(3'-[2'pyridyldithio]-propionamido) butane.
database_cross_reference: CAS:141647-62-3
database_cross_reference: ChemSpiderID:3398412
database_cross_reference: ChemicalBookNo:CB1775965
database_cross_reference: MDL:MFCD00153604
database_cross_reference: PubChem_Compound:4187644

Sulfo-DST
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: periodate cleavable
definition: Sulfodisuccinimidyl tartrate.
reaction sites: 2
spacer length: 6.4
has_obo_namespace: XLMOD
id: XLMOD:02080

Axiom
annotated source: Sulfo-DST
annotated property: definition
annotated target: Sulfodisuccinimidyl tartrate.
database_cross_reference: CAS:118674-04-7
database_cross_reference: ChemSpiderID:2338831
database_cross_reference: ChemicalBookNo:CB2297174
database_cross_reference: PubChem_Compound:3081171

Sulfo-GMBS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-gamma-Maleimidobutyryloxysulfosuccinimide ester.
reaction sites: 2
spacer length: 6.8
has_obo_namespace: XLMOD
id: XLMOD:02081

Axiom
annotated source: Sulfo-GMBS
annotated property: definition
annotated target: N-gamma-Maleimidobutyryloxysulfosuccinimide ester.
database_cross_reference: CAS:185332-92-7
database_cross_reference: ChemSpiderID:2678121
database_cross_reference: ChemicalBookNo:CB4412935
database_cross_reference: PubChem_Compound:23683309

EMCH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: N-(epsilon-Maleimidocaproic acid) hydrazide.
reaction sites: 2
spacer length: 11.8
has_obo_namespace: XLMOD
id: XLMOD:02082

Axiom
annotated source: EMCH
annotated property: definition
annotated target: N-(epsilon-Maleimidocaproic acid) hydrazide.
database_cross_reference: CAS:81186-33-6
database_cross_reference: ChemSpiderID:3381797
database_cross_reference: ChemicalBookNo:CB1298684
database_cross_reference: PubChem_Compound:4170354

EMCH-TFA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: N-(epsilon-Maleimidocaproic acid)hydrazide, TriFluoroacetic Acid.
reaction sites: 2
spacer length: 11.8
has_exact_synonym: 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic Acid Hydrazide 2,2,2-Trifluoroacetate
has_obo_namespace: XLMOD
id: XLMOD:02083

Axiom
annotated source: EMCH-TFA
annotated property: definition
annotated target: N-(epsilon-Maleimidocaproic acid)hydrazide, TriFluoroacetic Acid.
database_cross_reference: CAS:151038-94-7
database_cross_reference: ChemSpiderID:11567960
database_cross_reference: ChemicalBookNo:CB8349886
database_cross_reference: PubChem_Compound:23509306

Sulfo-EMCS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-(epsilon-Maleimidocaproyloxy) sulfo succinimide ester.
reaction sites: 2
spacer length: 9.4
has_exact_synonym: 6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester
has_obo_namespace: XLMOD
id: XLMOD:02084

Axiom
annotated source: Sulfo-EMCS
annotated property: definition
annotated target: N-(epsilon-Maleimidocaproyloxy) sulfo succinimide ester.
database_cross_reference: CAS:215312-86-0
database_cross_reference: ChemSpiderID:3438266
database_cross_reference: ChemicalBookNo:CB6793735
database_cross_reference: PubChem_Compound:4229287

PMPI
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: isocyanate
definition: N-(Maleimidophenyl) isocyanate.
reaction sites: 2
spacer length: 8.7
has_exact_synonym: N-(4-Isocyanatophenyl)maleimide
has_obo_namespace: XLMOD
id: XLMOD:02085

Axiom
annotated source: PMPI
annotated property: definition
annotated target: N-(Maleimidophenyl) isocyanate.
database_cross_reference: CAS:123457-83-0
database_cross_reference: ChemSpiderID:115040
database_cross_reference: ChemicalBookNo:CB7497652
database_cross_reference: PubChem_Compound:129975

SIAB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: iodoacetyl
definition: N-Succinimidyl(4-iodoacetyl)aminobenzoate.
reaction sites: 2
spacer length: 10.6
has_exact_synonym: 4-[(2-Iodoacetyl)amino]benzoic Acid 2,5-dioxo-1-pyrrolidinyl Ester
has_obo_namespace: XLMOD
id: XLMOD:02086

Axiom
annotated source: SIAB
annotated property: definition
annotated target: N-Succinimidyl(4-iodoacetyl)aminobenzoate.
database_cross_reference: CAS:72252-96-1
database_cross_reference: ChemSpiderID:112308
database_cross_reference: ChemicalBookNo:CB4386384
database_cross_reference: PubChem_Compound:126367

Sulfo-SIAB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: iodoacetyl
definition: N-Sulfosuccinimidyl(4-iodoacetyl)aminobenzoate.
reaction sites: 2
spacer length: 10.6
has_obo_namespace: XLMOD
id: XLMOD:02087

Axiom
annotated source: Sulfo-SIAB
annotated property: definition
annotated target: N-Sulfosuccinimidyl(4-iodoacetyl)aminobenzoate.
database_cross_reference: CAS:144650-93-1
database_cross_reference: ChemSpiderID:3343983
database_cross_reference: ChemicalBookNo:CB3328358
database_cross_reference: PubChem_Compound:4131104

Sulfo-SMPB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Sulfo succinimidyl 4-(maleimidophenyl) butyrate.
reaction sites: 2
spacer length: 11.6
has_obo_namespace: XLMOD
id: XLMOD:02088

Axiom
annotated source: Sulfo-SMPB
annotated property: definition
annotated target: Sulfo succinimidyl 4-(maleimidophenyl) butyrate.
database_cross_reference: CAS:92921-26-1
database_cross_reference: ChemSpiderID:32076952
database_cross_reference: ChemicalBookNo:CB5324783
database_cross_reference: PubChem_Compound:118855953

MAL-PEG4-SCM
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl-[(N-maleimidopropionamido)-tetraethyleneglycol] ester.
hydrophilic PE gchain: 4
reaction sites: 2
spacer length: 24.6
has_exact_synonym: Mal-PEG4-NHS-ester
has_exact_synonym: Malamido-PEG4-NHS
has_exact_synonym: Maleimide-PEG4-NHS
has_exact_synonym: NHS-PEG4-Maleimide
has_exact_synonym: O-[N-(3-Maleimidopropionyl)aminoethyl]-O'-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol
has_exact_synonym: SM[PEG]4
has_exact_synonym: Succinimidyl-[(N-maleimidopropionamido)-dodecaethyleneglycol] ester
has_obo_namespace: XLMOD
id: XLMOD:02089

Axiom
annotated source: MAL-PEG4-SCM
annotated property: definition
annotated target: Succinimidyl-[(N-maleimidopropionamido)-tetraethyleneglycol] ester.
database_cross_reference: CAS:756525-99-2
database_cross_reference: ChemSpiderID:32055651
database_cross_reference: ChemicalBookNo:CB22546917
database_cross_reference: PubChem_Compound:51340950

ABH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
definition: Azidobenzoyl hydrazide.
reaction sites: 2
spacer length: 11.9
has_obo_namespace: XLMOD
id: XLMOD:02090

Axiom
annotated source: ABH
annotated property: definition
annotated target: Azidobenzoyl hydrazide.
database_cross_reference: CAS:63296-32-2
database_cross_reference: ChemSpiderID:7988662
database_cross_reference: ChemicalBookNo:CB0135326
database_cross_reference: PubChem_Compound:9812912

APG
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenylglyoxal
definition: p-Azidophenyl glyoxal monohydrate.
reaction sites: 2
spacer length: 9.3
has_obo_namespace: XLMOD
id: XLMOD:02091

Axiom
annotated source: APG
annotated property: definition
annotated target: p-Azidophenyl glyoxal monohydrate.
database_cross_reference: CAS:1196151-49-1
database_cross_reference: ChemSpiderID:11564450
database_cross_reference: ChemicalBookNo:CB3774159
database_cross_reference: MDL:MFCD00150595

APDP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
reaction sites: 2
spacer length: 21.0
has_obo_namespace: XLMOD
id: XLMOD:02092

Axiom
annotated source: APDP
annotated property: definition
database_cross_reference: ChemSpiderID:8496824
database_cross_reference: ChemicalBookNo:CB7382675

BASED
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Bis(beta-[4-azidosalicylamido]-ethyl) disulfide.
reaction sites: 2
spacer length: 21.3
has_exact_synonym: Bis(2-(4-azidosalicylamido)ethyl) disulfide
has_exact_synonym: N, N'-(Dithiobis-ethylene)bis(4-azido-2-hydroxy-benzamide)
has_exact_synonym: N,N'-Bis(4-azidosalicoyl)cystamine
has_obo_namespace: XLMOD
id: XLMOD:02093

Axiom
annotated source: BASED
annotated property: definition
annotated target: Bis(beta-[4-azidosalicylamido]-ethyl) disulfide.
database_cross_reference: CAS:199804-21-2
database_cross_reference: ChemSpiderID:2891936
database_cross_reference: ChemicalBookNo:CB3363805
database_cross_reference: PubChem_Compound:3658531

NHS-ASA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
definition: N-Hydroxysuccinimidyl-4-azidosalicyclic acid.
reaction sites: 2
spacer length: 8.0
has_exact_synonym: 1-[(4-Azido-2-hydroxybenzoyl)oxy]-2,5-pyrrolidinedione
has_obo_namespace: XLMOD
id: XLMOD:02094

Axiom
annotated source: NHS-ASA
annotated property: definition
annotated target: N-Hydroxysuccinimidyl-4-azidosalicyclic acid.
database_cross_reference: CAS:96602-46-9
database_cross_reference: ChemSpiderID:2299834
database_cross_reference: ChemicalBookNo:CB21334997
database_cross_reference: PMID:2358439
database_cross_reference: PubChem_Compound:3035647

Sulfo-HSAB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
definition: N-Hydroxysulfosuccinimidyl-4-azidobenzoate.
reaction sites: 2
spacer length: 9.0
has_obo_namespace: XLMOD
id: XLMOD:02095

Axiom
annotated source: Sulfo-HSAB
annotated property: definition
annotated target: N-Hydroxysulfosuccinimidyl-4-azidobenzoate.
database_cross_reference: CAS:199804-22-3
database_cross_reference: ChemSpiderID:8466468
database_cross_reference: ChemicalBookNo:CB5222018
database_cross_reference: PubChem_Compound:10290999

Sulfo-SAED
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: azido-methylcoumarin
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Sulfosuccinimidyl 2-(7-amino-4-methylcoumarin-3-acetamido)ethyl-1,3-dithiopropionate.
reaction sites: 2
spacer length: 23.6
has_exact_synonym: 2-SAED
has_obo_namespace: XLMOD
id: XLMOD:02096

Axiom
annotated source: Sulfo-SAED
annotated property: definition
annotated target: Sulfosuccinimidyl 2-(7-amino-4-methylcoumarin-3-acetamido)ethyl-1,3-dithiopropionate.
database_cross_reference: ChemSpiderID:116802
database_cross_reference: PubChem_Compound:132249

Sulfo-SAND
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Sulfosuccinimidyl 2-(m-azido-o-nitrobenzamido)-ethyl-1,3'-dithiopropionate.
reaction sites: 2
spacer length: 18.5
has_obo_namespace: XLMOD
id: XLMOD:02097

Axiom
annotated source: Sulfo-SAND
annotated property: definition
annotated target: Sulfosuccinimidyl 2-(m-azido-o-nitrobenzamido)-ethyl-1,3'-dithiopropionate.
database_cross_reference: MDL:MFCD02091654

SANPAH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
definition: N-Succinimidyl 6-(4-azido-2-nitroanilino)hexanoate.
reaction sites: 2
spacer length: 18.2
has_exact_synonym: 6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester
has_obo_namespace: XLMOD
id: XLMOD:02098

Axiom
annotated source: SANPAH
annotated property: definition
annotated target: N-Succinimidyl 6-(4-azido-2-nitroanilino)hexanoate.
database_cross_reference: CAS:64309-05-3
database_cross_reference: ChemSpiderID:2299761
database_cross_reference: ChemicalBookNo:CB2262231
database_cross_reference: PubChem_Compound:3035550

Sulfo-SADP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Sulfosuccinimidyl (4-azidophenyl)-1,3'-dithiopropionate.
reaction sites: 2
spacer length: 13.9
has_obo_namespace: XLMOD
id: XLMOD:02099

Axiom
annotated source: Sulfo-SADP
annotated property: definition
annotated target: Sulfosuccinimidyl (4-azidophenyl)-1,3'-dithiopropionate.
database_cross_reference: CAS:102568-45-6
database_cross_reference: ChemSpiderID:113597
database_cross_reference: ChemicalBookNo:CB9210802
database_cross_reference: PubChem_Compound:128116

SASD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Succinimidyl-2-(azidosalicylamido)ethyl-1,3-dithiopropionate.
reaction sites: 2
spacer length: 18.9
has_obo_namespace: XLMOD
id: XLMOD:02100

Axiom
annotated source: SASD
annotated property: definition
annotated target: Succinimidyl-2-(azidosalicylamido)ethyl-1,3-dithiopropionate.
database_cross_reference: CAS:144650-95-3
database_cross_reference: ChemSpiderID:3286667
database_cross_reference: ChemicalBookNo:CB9276943
database_cross_reference: PubChem_Compound:4071585

Sulfo-SASD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Sulfosuccinimidyl-2-(azidosalicylamido)ethyl-1,3-dithiopropionate.
reaction sites: 2
spacer length: 18.9
has_obo_namespace: XLMOD
id: XLMOD:02101

Axiom
annotated source: Sulfo-SASD
annotated property: definition
annotated target: Sulfosuccinimidyl-2-(azidosalicylamido)ethyl-1,3-dithiopropionate.
database_cross_reference: CAS:144650-95-3
database_cross_reference: ChemSpiderID:3286667
database_cross_reference: ChemicalBookNo:CB9276943
database_cross_reference: PubChem_Compound:6098351

DTTDPS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: periodate cleavable
definition: DTTDPS cross-linker.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02102

Axiom
annotated source: DTTDPS
annotated property: definition
annotated target: DTTDPS cross-linker.
database_cross_reference: PMID:20109223

1,4-diacetalbenzene
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: glyoxal
definition: 1,4-diacetalbenzene reagent.
mono isotopic mass: 190.027
reaction sites: 2
spacer length: 7.5
has_exact_synonym: PDG
has_exact_synonym: Phenyldiglyoxal
has_obo_namespace: XLMOD
id: XLMOD:02103

Axiom
annotated source: 1,4-diacetalbenzene
annotated property: definition
annotated target: 1,4-diacetalbenzene reagent.
database_cross_reference: CAS:1074-12-0
database_cross_reference: ChemSpiderID:13470
database_cross_reference: ChemicalBookNo:CB3357077
database_cross_reference: PMID:16875836
database_cross_reference: PMID:18936057
database_cross_reference: PubChem_Compound:14090

DiBMADPS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: mass defect labelled
definition: Bis(2,5-dioxopyrrolidin-1-yl)3,3'-(3,5-dibromo-4-methylphenylazanediyl)diproponate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02104

Axiom
annotated source: DiBMADPS
annotated property: definition
annotated target: Bis(2,5-dioxopyrrolidin-1-yl)3,3'-(3,5-dibromo-4-methylphenylazanediyl)diproponate.
database_cross_reference: https://getd.libs.uga.edu/pdfs/hoffman_lisabeth_l_201008_phd.pdf

DiBBSIAS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: mass defect labelled
definition: Bis(2,5-dioxopyrrolidin-1-yl) 2,2'-(2,4-dibromophenylsulfonylazanediyl)diacetate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02105

Axiom
annotated source: DiBBSIAS
annotated property: definition
annotated target: Bis(2,5-dioxopyrrolidin-1-yl) 2,2'-(2,4-dibromophenylsulfonylazanediyl)diacetate.
database_cross_reference: https://getd.libs.uga.edu/pdfs/hoffman_lisabeth_l_201008_phd.pdf

BID
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
CID fragment: 275.1
CID fragment: 91.0
definition: N-benzyliminodiacetoyloxysuccinimid.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02106

Axiom
annotated source: BID
annotated property: definition
annotated target: N-benzyliminodiacetoyloxysuccinimid.
database_cross_reference: PMID:11212007

BCCL1
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Bis-(N-hydroxysuccinimidyl) 3-amino-N-biotinoyl-1,5-pentanedioate.
mono isotopic mass: 337.10962
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02107

Axiom
annotated source: BCCL1
annotated property: definition
annotated target: Bis-(N-hydroxysuccinimidyl) 3-amino-N-biotinoyl-1,5-pentanedioate.
database_cross_reference: PMID:19412923

BCCL2
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Bis-(N-hydroxysuccinimidyl) 5-amino-N-biotinoyl-1,9-nonanedioate.
mono isotopic mass: 393.17222
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02108

Axiom
annotated source: BCCL2
annotated property: definition
annotated target: Bis-(N-hydroxysuccinimidyl) 5-amino-N-biotinoyl-1,9-nonanedioate.
database_cross_reference: PMID:19412923

SBC
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
definition: N-succinimidyl p-benzoyldihydrocinnamate.
mono isotopic mass: 236.09
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02109

Axiom
annotated source: SBC
annotated property: definition
annotated target: N-succinimidyl p-benzoyldihydrocinnamate.
database_cross_reference: ChemSpiderID:4488161
database_cross_reference: PMID:19653199

SBDC
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled N-succinimidyl p-benzoyldihydrocinnamate.
doublet delta mass: 2.01254
mono isotopic mass: 238.1
reaction sites: 2
has_exact_synonym: SBC-d2
has_obo_namespace: XLMOD
id: XLMOD:02110

Axiom
annotated source: SBDC
annotated property: definition
annotated target: Deuterium labelled N-succinimidyl p-benzoyldihydrocinnamate.
database_cross_reference: PMID:19653199

S-Methyl 5,5'-thiodipentanoylhydroxysuccinimidemethylsulfate
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: S-Methyl 5,5'-thiodipentanoylhydroxysuccinimidemethylsulfate cross-linker.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02111

Axiom
annotated source: S-Methyl 5,5'-thiodipentanoylhydroxysuccinimidemethylsulfate
annotated property: definition
annotated target: S-Methyl 5,5'-thiodipentanoylhydroxysuccinimidemethylsulfate cross-linker.
database_cross_reference: PMID:19551991

SuDP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
CID fragment: 197.0324
CID fragment: 97.0528
definition: Bisuccinimidyl-succinamyl-aspartyl-proline.
reaction sites: 2
spacer length: 11.2
has_exact_synonym: Disuccinimidyl-succinamyl-aspartyl-proline
has_obo_namespace: XLMOD
id: XLMOD:02112

Axiom
annotated source: SuDP
annotated property: definition
annotated target: Bisuccinimidyl-succinamyl-aspartyl-proline.
database_cross_reference: PMID:17134140
database_cross_reference: PMID:20560670
database_cross_reference: PMID:26091612

SuDPG
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
CID fragment: 154.1
CID fragment: 197.1
CID fragment: 215.1
CID fragment: 97.1
definition: Bisuccinimidyl-succinamyl-aspartyl-prolyl-glycine.
reaction sites: 2
spacer length: 15.1
has_exact_synonym: Disuccinimidyl-succinamyl-aspartyl-prolyl-glycine
has_obo_namespace: XLMOD
id: XLMOD:02113

Axiom
annotated source: SuDPG
annotated property: definition
annotated target: Bisuccinimidyl-succinamyl-aspartyl-prolyl-glycine.
database_cross_reference: PMID:17134140
database_cross_reference: PMID:26091612

IRCX
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Dibenzoyloxysuccinimidylethyl phosphate.
mono isotopic mass: 330.0
reaction sites: 2
spacer length: 16.0
has_obo_namespace: XLMOD
id: XLMOD:02114
comment: An IR chromogenic crosslinker.

Axiom
annotated source: IRCX
annotated property: definition
annotated target: Dibenzoyloxysuccinimidylethyl phosphate.
database_cross_reference: PMID:18517224

BAMG
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: TCEP cleavable
definition: Bis(succinimidyl)-3-azidomethyl glutarate.
mono isotopic mass: 125.048
reaction sites: 2
spacer length: 7.5
has_obo_namespace: XLMOD
id: XLMOD:02115

Axiom
annotated source: BAMG
annotated property: definition
annotated target: Bis(succinimidyl)-3-azidomethyl glutarate.
database_cross_reference: PMID:17600791

azide-DSG
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Bis(succinimidyl)-3-azidomethyl glutarate.
mono isotopic mass: 211.0
reaction sites: 2
spacer length: 7.7
has_obo_namespace: XLMOD
id: XLMOD:02116

Axiom
annotated source: azide-DSG
annotated property: definition
annotated target: Bis(succinimidyl)-3-azidomethyl glutarate.
database_cross_reference: PMID:20472459

1
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Crosslinking reagent 1.
reaction sites: 2
spacer length: 8.7
has_obo_namespace: XLMOD
id: XLMOD:02117

Axiom
annotated source: 1
annotated property: definition
annotated target: Crosslinking reagent 1.
database_cross_reference: PMID:14698174

JMV 3378
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: CHCA
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Crosslinking reagent JMV 3378.
mono isotopic mass: 268.0
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02118

Axiom
annotated source: JMV 3378
annotated property: definition
annotated target: Crosslinking reagent JMV 3378.
database_cross_reference: PMID:19902427

BuTuGPG
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: 4-[3-(2-{2-[(2,5-dioxo-pyrrolidin-1-yloxycarbonyl-methyl)-carbamoyl]-pyrrolidin-1-yl}-2-oxo-ethyl)-thioureido]-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester.
mono isotopic mass: 1686.84
reaction sites: 2
spacer length: 16.7
has_exact_synonym: Edman linker
has_exact_synonym: NHS-BuTuGPG-NHS
has_exact_synonym: NHS-butyric acid-thiourea-glycine-proline-glycine-NHS
has_obo_namespace: XLMOD
id: XLMOD:02119

Axiom
annotated source: BuTuGPG
annotated property: definition
annotated target: 4-[3-(2-{2-[(2,5-dioxo-pyrrolidin-1-yloxycarbonyl-methyl)-carbamoyl]-pyrrolidin-1-yl}-2-oxo-ethyl)-thioureido]-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester.
database_cross_reference: PMID:19950134

BuUrBu
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_neutral_loss_reporter
  some values from: generic neutral loss reporter
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: NHS-amino butyric acid-urea-amino butyric acid-NHS.
bridge formula: C9 H12 N2 O3
doublet delta mass: 25.979
mono isotopic mass: 196.084792
neutral loss formula: -H2 -O1
neutral loss formula: -H3 -N1
reaction sites: 2
spacer length: 12.5
stub formula: CID = : C9 H12 N2 O3
stub formula: CID = C3 H7 N1 O1 : C5 H5 N1 O2
stub formula: CID = C5 H7 N1 O2 : C4 H5 N1 O1
has_exact_synonym: DSBU
has_exact_synonym: Disuccinimidyl dibutyric urea
has_exact_synonym: NHS-BuUrBu-NHS
has_obo_namespace: XLMOD
id: XLMOD:02120

Axiom
annotated source: BuUrBu
annotated property: definition
annotated target: NHS-amino butyric acid-urea-amino butyric acid-NHS.
database_cross_reference: CAS:1240387-33-0
database_cross_reference: ChemSpiderID:65999926
database_cross_reference: PMID:20704385
database_cross_reference: PMID:21157862
database_cross_reference: PMID:25261217
database_cross_reference: PMID:27428000
database_cross_reference: PMID:30074391
database_cross_reference: PubChem_Compound:86106597

DPS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: N-hydroxyphthalimide
definition: Diphtalimide suberate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02121
comment: Contains an eight-carbon spacer arm.

Axiom
annotated source: DPS
annotated property: definition
annotated target: Diphtalimide suberate.
database_cross_reference: PMID:19994840

SBBT
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxybenzotriazole
definition: 1,1'-(suberoyldioxy)bisbenzotriazole.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02122
comment: Contains an eight-carbon spacer arm.

Axiom
annotated source: SBBT
annotated property: definition
annotated target: 1,1'-(suberoyldioxy)bisbenzotriazole.
database_cross_reference: PMID:19994840

SBAT
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: 1-hydroxy-7-azabenzotriazole
definition: 1,1'-(suberoyldioxy)bisazabenzotriazole.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02123
comment: Contains an eight-carbon spacer arm.

Axiom
annotated source: SBAT
annotated property: definition
annotated target: 1,1'-(suberoyldioxy)bisazabenzotriazole.
database_cross_reference: PMID:19994840

SDAD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_neutral_loss_reporter
  some values from: generic neutral loss reporter
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Succinimidyl 2-([4,4'-azipentanamido]ethyl)-1,3'-dithiopropionate.
mono isotopic mass: 273.0
reaction sites: 2
spacer length: 13.5
has_exact_synonym: NHS-SS-Diazirine
has_obo_namespace: XLMOD
id: XLMOD:02124

Axiom
annotated source: SDAD
annotated property: definition
annotated target: Succinimidyl 2-([4,4'-azipentanamido]ethyl)-1,3'-dithiopropionate.
database_cross_reference: PMID:20635431
database_cross_reference: PMID:25251153

Sulfo-SDAD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_neutral_loss_reporter
  some values from: generic neutral loss reporter
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Sulfosuccinimidyl 2-([4,4'-azipentanamido]ethyl)-1,3'-dithiopropionate.
mono isotopic mass: 273.0
reaction sites: 2
spacer length: 13.5
has_exact_synonym: Sulfo-NHS-SS-Diazirine
has_obo_namespace: XLMOD
id: XLMOD:02125

Axiom
annotated source: Sulfo-SDAD
annotated property: definition
annotated target: Sulfosuccinimidyl 2-([4,4'-azipentanamido]ethyl)-1,3'-dithiopropionate.
database_cross_reference: CAS:1226983-32-9
database_cross_reference: PubChem_Compound:124202976

DSSO
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable C-S bond
definition: Disuccinimidyl sulfoxide.
bridge formula: C6 O3 S1 H6
mono isotopic mass: 158.0037648
reaction sites: 2
spacer length: 10.1
stub formula: CID = H4 C3 O2 S1, -H2 -O1 : H2 C3 O1
has_obo_namespace: XLMOD
id: XLMOD:02126

Axiom
annotated source: DSSO
annotated property: definition
annotated target: Disuccinimidyl sulfoxide.
database_cross_reference: ChemSpiderID:65999926
database_cross_reference: PMID:20736410
database_cross_reference: PMID:27417384
database_cross_reference: PubChem_Compound:86106597

DEST
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: thioimidate
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Diethylsuberthioimidate.
bridge formula: C8 H12 N2
mono isotopic mass: 136.10004842
reaction sites: 2
spacer length: 11.0
has_obo_namespace: XLMOD
id: XLMOD:02127

Axiom
annotated source: DEST
annotated property: definition
annotated target: Diethylsuberthioimidate.
database_cross_reference: ChemSpiderID:67491002
database_cross_reference: PMID:20795639
database_cross_reference: PMID:22460622
database_cross_reference: PubChem_Compound:88869905

cis-Diamminedichloroplatinum (II)
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: platinum(II)
definition: Cis-[Pt(NH3)2Cl2].
mono isotopic mass: 225.995
reaction sites: 2
spacer length: 4.63
has_exact_synonym: CPT
has_exact_synonym: Cis-platin
has_obo_namespace: XLMOD
id: XLMOD:02128

Axiom
annotated source: cis-Diamminedichloroplatinum (II)
annotated property: definition
annotated target: Cis-[Pt(NH3)2Cl2].
database_cross_reference: CAS:15663-27-1
database_cross_reference: ChemSpiderID:76401
database_cross_reference: ChemicalBookNo:CB9236183
database_cross_reference: PMID:16875836
database_cross_reference: PMID:21591778
database_cross_reference: PubChem_Compound:441203

DC4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable by MS2 labile bond
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: ISD cleavable
definition: DC4 cross-linker containing a DABCO (1,4-diazabicyclo[2.2.2]octane) moiety.
reaction sites: 2
spacer length: 18.0
has_obo_namespace: XLMOD
id: XLMOD:02129

Axiom
annotated source: DC4
annotated property: definition
annotated target: DC4 cross-linker containing a DABCO (1,4-diazabicyclo[2.2.2]octane) moiety.
database_cross_reference: CAS:1374647-94-5
database_cross_reference: ChemSpiderID:29763722
database_cross_reference: ChemicalBookNo:CB63152601
database_cross_reference: PMID:22131227

ASBA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: 4-(p-Azidosalicylamido)butylamine.
reaction sites: 2
spacer length: 16.3
has_obo_namespace: XLMOD
id: XLMOD:02130

Axiom
annotated source: ASBA
annotated property: definition
annotated target: 4-(p-Azidosalicylamido)butylamine.
database_cross_reference: ChemSpiderID:8013538
database_cross_reference: ChemicalBookNo:CB0295398
database_cross_reference: MDL:MFCD00153599

SPB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: psoralen
definition: Succinimidyl-[4-(psoralen-8-yloxy)]-butyrate.
reaction sites: 2
spacer length: 8.6
has_exact_synonym: NHS-Psoralen
has_obo_namespace: XLMOD
id: XLMOD:02131

Axiom
annotated source: SPB
annotated property: definition
annotated target: Succinimidyl-[4-(psoralen-8-yloxy)]-butyrate.
database_cross_reference: CAS:129211-47-8
database_cross_reference: ChemicalBookNo:CB5449965
database_cross_reference: MDL:MFCD01868521
database_cross_reference: PubChem_Compound:15950836

Sulfo-NHS-LC-ASA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
definition: Sulfosuccinimidyl(4-azido-salicylamido) hexanoate.
reaction sites: 2
spacer length: 18.0
has_exact_synonym: SAH
has_exact_synonym: Sulfo-NHS-Long Chain-ASA
has_obo_namespace: XLMOD
id: XLMOD:02132

Axiom
annotated source: Sulfo-NHS-LC-ASA
annotated property: definition
annotated target: Sulfosuccinimidyl(4-azido-salicylamido) hexanoate.
database_cross_reference: CAS:184533-12-8
database_cross_reference: ChemSpiderID:8337730
database_cross_reference: ChemicalBookNo:CB8475750
database_cross_reference: PubChem_Compound:10162222

Sulfo-SFAD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: perfluoroaryl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Sulfosuccinimidyl(perfluoroazidobenzamido)ethyl-1,3´-dithiopropionate.
reaction sites: 2
spacer length: 14.6
has_obo_namespace: XLMOD
id: XLMOD:02133

Axiom
annotated source: Sulfo-SFAD
annotated property: definition
annotated target: Sulfosuccinimidyl(perfluoroazidobenzamido)ethyl-1,3´-dithiopropionate.
database_cross_reference: CAS:220446-74-2
database_cross_reference: ChemSpiderID:30798432
database_cross_reference: ChemicalBookNo:CB9178443
database_cross_reference: PubChem_Compound:90471066

SDA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
definition: Succinimidyl-ester diazirine.
bridge formula: C5 H6 O1
mono isotopic mass: 82.04186484
reaction sites: 2
spacer length: 3.9
has_exact_synonym: NHS-Diazirine
has_obo_namespace: XLMOD
id: XLMOD:02134

Axiom
annotated source: SDA
annotated property: definition
annotated target: Succinimidyl-ester diazirine.
database_cross_reference: MDL:MFCD28899672
database_cross_reference: PubChem_Compound:89937136

LC-SDA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
definition: NHS-LC-Diazirine.
bridge formula: C11 H12 N1 O2
mono isotopic mass: 195.125928855
reaction sites: 2
spacer length: 12.5
has_exact_synonym: Long Chain-SDA
has_exact_synonym: NHS-LC-Diazirine
has_exact_synonym: Succinimidyl 6-(4,4'-azipentanamido)hexanoate
has_obo_namespace: XLMOD
id: XLMOD:02135

Axiom
annotated source: LC-SDA
annotated property: definition
annotated target: NHS-LC-Diazirine.
database_cross_reference: PSI:XL

Sulfo-SDA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: Sulfo-NHS-Diazirine.
reaction sites: 2
spacer length: 3.9
has_exact_synonym: Sulfosuccinimidyl 4,4'-azipentanoate
has_obo_namespace: XLMOD
id: XLMOD:02136

Axiom
annotated source: Sulfo-SDA
annotated property: definition
annotated target: Sulfo-NHS-Diazirine.
database_cross_reference: PMID:28430416
database_cross_reference: PubChem_Compound:121371016

Sulfo-LC-SDA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
definition: Sulfo-NHS-LC-Diazirine.
reaction sites: 2
spacer length: 12.5
has_exact_synonym: Sulfosuccinimidyl 6-(4,4'-azipentanamido)hexanoate
has_obo_namespace: XLMOD
id: XLMOD:02137

Axiom
annotated source: Sulfo-LC-SDA
annotated property: definition
annotated target: Sulfo-NHS-LC-Diazirine.
database_cross_reference: CAS:1909307-62-5
database_cross_reference: MDL:MFCD28899432
database_cross_reference: PubChem_Compound:124202974

DMA
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: imidoester
definition: Dimethyl adipimidate dihydrochloride.
reaction sites: 2
spacer length: 8.6
has_obo_namespace: XLMOD
id: XLMOD:02138

Axiom
annotated source: DMA
annotated property: definition
annotated target: Dimethyl adipimidate dihydrochloride.
database_cross_reference: CAS:14620-72-5
database_cross_reference: ChemSpiderID:34991296
database_cross_reference: ChemicalBookNo:CB4714688
database_cross_reference: PubChem_Compound:25738

DMP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: imidoester
definition: Dimethyl pimelimidate dihydrochloride.
bridge formula: C7 H10 N2
mono isotopic mass: 122.08439835
reaction sites: 2
spacer length: 9.2
has_exact_synonym: Dimethyl pimelinediimidate dihydrochloride
has_obo_namespace: XLMOD
id: XLMOD:02139

Axiom
annotated source: DMP
annotated property: definition
annotated target: Dimethyl pimelimidate dihydrochloride.
database_cross_reference: CAS:58537-94-3
database_cross_reference: ChemSpiderID:10637821
database_cross_reference: ChemicalBookNo:CB7380424
database_cross_reference: PubChem_Compound:11402688

DMS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: imidoester
definition: Dimethyl suberimidate dihydrochloride.
reaction sites: 2
spacer length: 11.0
has_exact_synonym: 1,8-Dimethoxyoctane-1,8-diyldiammonium dichloride
has_exact_synonym: Dimethyl ester octanediimidic acid dihydrochloride
has_obo_namespace: XLMOD
id: XLMOD:02140

Axiom
annotated source: DMS
annotated property: definition
annotated target: Dimethyl suberimidate dihydrochloride.
database_cross_reference: CAS:34490-86-3
database_cross_reference: ChemicalBookNo:CB9142806
database_cross_reference: PubChem_Compound:118696

DTBP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: imidoester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Dimethyl 3,3'-dithiobispropionimidate dihydrochloride.
reaction sites: 2
spacer length: 11.9
has_obo_namespace: XLMOD
id: XLMOD:02141

Axiom
annotated source: DTBP
annotated property: definition
annotated target: Dimethyl 3,3'-dithiobispropionimidate dihydrochloride.
database_cross_reference: CAS:38285-78-8
database_cross_reference: ChemSpiderID:10628577
database_cross_reference: ChemicalBookNo:CB5208751
database_cross_reference: PubChem_Compound:123988

Sulfo-BSOCOES
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: base cleavable
definition: Bis(2-[Sulfosuccinimidooxycarbonyloxy]ethyl) sulfone.
reaction sites: 2
spacer length: 13.0
has_obo_namespace: XLMOD
id: XLMOD:02142

Axiom
annotated source: Sulfo-BSOCOES
annotated property: definition
annotated target: Bis(2-[Sulfosuccinimidooxycarbonyloxy]ethyl) sulfone.
database_cross_reference: CAS:161011-72-9
database_cross_reference: ChemicalBookNo:CB62131214
database_cross_reference: PMID:7356718
database_cross_reference: PubChem_Compound:10232304

BMH
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 1,6-Bis-maleimidohexane.
reaction sites: 2
spacer length: 16.1
has_obo_namespace: XLMOD
id: XLMOD:02143

Axiom
annotated source: BMH
annotated property: definition
annotated target: 1,6-Bis-maleimidohexane.
database_cross_reference: CAS:4856-87-5
database_cross_reference: ChemSpiderID:19746
database_cross_reference: ChemicalBookNo:CB9745265
database_cross_reference: PubChem_Compound:20992

DFDNB
type: Class
subclass of: homofunctional cross-linker
subclass of: Sanger type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl halide
definition: 1-5-Difluoro-2,4-dinitrobenzene.
reaction sites: 2
spacer length: 3.0
has_obo_namespace: XLMOD
id: XLMOD:02144

Axiom
annotated source: DFDNB
annotated property: definition
annotated target: 1-5-Difluoro-2,4-dinitrobenzene.
database_cross_reference: CAS:327-92-4
database_cross_reference: ChemSpiderID:60919
database_cross_reference: ChemicalBookNo:CB2488813
database_cross_reference: PubChem_Compound:67598

SMPT
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: 4-Succinimidyloxycarbonyl-methyl-alpha-(2-pyridyldithio)toluene.
reaction sites: 2
spacer length: 11.2
has_obo_namespace: XLMOD
id: XLMOD:02145

Axiom
annotated source: SMPT
annotated property: definition
annotated target: 4-Succinimidyloxycarbonyl-methyl-alpha-(2-pyridyldithio)toluene.
database_cross_reference: CAS:112241-19-7
database_cross_reference: ChemSpiderID:115608
database_cross_reference: ChemicalBookNo:CB5359464
database_cross_reference: MDL:MFCD00083161
database_cross_reference: PubChem_Compound:130706

SDBP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: bromoacetyl
definition: N-hydroxysuccinimidyl-2-3-dibromopropionate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02146

Axiom
annotated source: SDBP
annotated property: definition
annotated target: N-hydroxysuccinimidyl-2-3-dibromopropionate.
database_cross_reference: CAS:118790-78-6
database_cross_reference: ChemSpiderID:169350
database_cross_reference: ChemicalBookNo:CB61318997
database_cross_reference: PubChem_Compound:195278

HSAB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
definition: N-hydroxysuccinimidyl 4-azidobenzoate.
reaction sites: 2
spacer length: 9.0
has_exact_synonym: 2,5-dioxopyrrolidin-1-yl) 4-azidobenzoate
has_exact_synonym: 4-Azidobenzoyloxysuccinimide
has_obo_namespace: XLMOD
id: XLMOD:02147

Axiom
annotated source: HSAB
annotated property: definition
annotated target: N-hydroxysuccinimidyl 4-azidobenzoate.
database_cross_reference: CAS:53053-08-0
database_cross_reference: ChemSpiderID:108951
database_cross_reference: ChemicalBookNo:CB5187007
database_cross_reference: MDL:MFCD00054963
database_cross_reference: PubChem_Compound:122153

ASIB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: iodoacetyl
definition: 1-(p-azidosalicylamido)-4-(iodoacetamido)butane.
reaction sites: 2
spacer length: 18.8
has_exact_synonym: 1-(4-Azidosalicylamido)-4-(iodoacetamido)butane
has_exact_synonym: 4-Azido-2-hydroxy-N-{4-[(iodoacetyl)amino]butyl}benzamide
has_obo_namespace: XLMOD
id: XLMOD:02148

Axiom
annotated source: ASIB
annotated property: definition
annotated target: 1-(p-azidosalicylamido)-4-(iodoacetamido)butane.
database_cross_reference: ChemSpiderID:8177587
database_cross_reference: ChemicalBookNo:CB3741230
database_cross_reference: PubChem_Compound:10002006

SAND
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: thiol cleavable
definition: Succinimidyl-2-[m-azido-o-nitrobenzamido]ethyl-1,3'-dithiopropionate.
reaction sites: 2
spacer length: 18.5
has_obo_namespace: XLMOD
id: XLMOD:02149

Axiom
annotated source: SAND
annotated property: definition
annotated target: Succinimidyl-2-[m-azido-o-nitrobenzamido]ethyl-1,3'-dithiopropionate.
database_cross_reference: MDL:MFCD02091654

SADP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: N-Succinimidyl (4-azidophenyl) 1,3´-dithiopropionate.
reaction sites: 2
spacer length: 13.9
has_obo_namespace: XLMOD
id: XLMOD:02150

Axiom
annotated source: SADP
annotated property: definition
annotated target: N-Succinimidyl (4-azidophenyl) 1,3´-dithiopropionate.
database_cross_reference: CAS:74676-98-5
database_cross_reference: ChemSpiderID:432600
database_cross_reference: ChemicalBookNo:CB7748141
database_cross_reference: PubChem_Compound:494250

PNP-DTP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrophenyl azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazo group
definition: p-nitrophenyl-2-diazo-3,3,3-trifluoropropionate.
reaction sites: 2
spacer length: 10.0
has_obo_namespace: XLMOD
id: XLMOD:02151

Axiom
annotated source: PNP-DTP
annotated property: definition
annotated target: p-nitrophenyl-2-diazo-3,3,3-trifluoropropionate.
database_cross_reference: CAS:59733-94-7
database_cross_reference: ChemSpiderID:11489106
database_cross_reference: ChemicalBookNo:CB41358102
database_cross_reference: PubChem_Compound:5748175

SAED
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: azido-methylcoumarin
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Succinimidyl-2-(7-azido-4-methylcoumarin-3-acetamido)ethyl-1,3'-dithiopropionate.
reaction sites: 2
spacer length: 23.6
has_obo_namespace: XLMOD
id: XLMOD:02152

Axiom
annotated source: SAED
annotated property: definition
annotated target: Succinimidyl-2-(7-azido-4-methylcoumarin-3-acetamido)ethyl-1,3'-dithiopropionate.
database_cross_reference: CAS:139609-20-4,PubChem_Compound:90469951
database_cross_reference: ChemSpiderID:52563941
database_cross_reference: ChemicalBookNo:CB5455874
database_cross_reference: PMID:1597185

Sulfo-SAMCA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: azido-methylcoumarin
definition: Sulfosuccinimidyl-7-azido-4-methylcoumarin-3-acetate.
reaction sites: 2
spacer length: 12.8
has_obo_namespace: XLMOD
id: XLMOD:02153

Axiom
annotated source: Sulfo-SAMCA
annotated property: definition
annotated target: Sulfosuccinimidyl-7-azido-4-methylcoumarin-3-acetate.
database_cross_reference: CAS:223572-57-4
database_cross_reference: ChemSpiderID:8313404
database_cross_reference: ChemicalBookNo:CB02702784
database_cross_reference: PubChem_Compound:10137892

MSA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Methyl N-succinimidyl adipate.
reaction sites: 2
spacer length: 7.2
has_obo_namespace: XLMOD
id: XLMOD:02154

Axiom
annotated source: MSA
annotated property: definition
annotated target: Methyl N-succinimidyl adipate.
database_cross_reference: CAS:118380-06-6
database_cross_reference: ChemSpiderID:3657094
database_cross_reference: ChemicalBookNo:CB3716645
database_cross_reference: PubChem_Compound:4458286

Maleimide-PEG2-NHS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl-[(N-maleimidopropionamido)-diethyleneglycol] ester.
hydrophilic PE gchain: 2
reaction sites: 2
spacer length: 17.6
has_exact_synonym: Malamido-PEG2-NHS
has_exact_synonym: NHS-PEG2-Maleimide
has_exact_synonym: SM[PEG]2
has_exact_synonym: Succinimide-Maleimide PEG
has_obo_namespace: XLMOD
id: XLMOD:02155

Axiom
annotated source: Maleimide-PEG2-NHS
annotated property: definition
annotated target: Succinimidyl-[(N-maleimidopropionamido)-diethyleneglycol] ester.
database_cross_reference: CAS:955094-26-5
database_cross_reference: ChemSpiderID:32055652
database_cross_reference: ChemicalBookNo:CB22501435
database_cross_reference: MDL:MFCD11041137
database_cross_reference: PubChem_Compound:51340948

Maleimide-PEG6-NHS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl-[(N-maleimidopropionamido)-hexaethyleneglycol] ester.
hydrophilic PE gchain: 6
reaction sites: 2
spacer length: 32.5
has_exact_synonym: Malamido-PEG6-NHS
has_exact_synonym: NHS-PEG6-Maleimide
has_exact_synonym: SM[PEG]6
has_obo_namespace: XLMOD
id: XLMOD:02156

Axiom
annotated source: Maleimide-PEG6-NHS
annotated property: definition
annotated target: Succinimidyl-[(N-maleimidopropionamido)-hexaethyleneglycol] ester.
database_cross_reference: CAS:1137109-21-7
database_cross_reference: ChemSpiderID:32055650
database_cross_reference: ChemicalBookNo:CB82546919
database_cross_reference: MDL:MFCD11041093
database_cross_reference: PubChem_Compound:77078209

Maleimide-PEG8-NHS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl-[(N-maleimidopropionamido)-octaethyleneglycol] ester.
hydrophilic PE gchain: 8
reaction sites: 2
spacer length: 39.25
has_exact_synonym: Malamido-PEG8-NHS
has_exact_synonym: NHS-PEG8-Maleimide
has_exact_synonym: SM[PEG]8
has_obo_namespace: XLMOD
id: XLMOD:02157

Axiom
annotated source: Maleimide-PEG8-NHS
annotated property: definition
annotated target: Succinimidyl-[(N-maleimidopropionamido)-octaethyleneglycol] ester.
database_cross_reference: CAS:756525-93-6
database_cross_reference: ChemSpiderID:32055649
database_cross_reference: ChemicalBookNo:CB62546920
database_cross_reference: MDL:MFCD11041144
database_cross_reference: PubChem_Compound:57568672

Maleimide-PEG12-NHS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl-[(N-maleimidopropionamido)-dodecaethyleneglycol] ester.
hydrophilic PE gchain: 12
reaction sites: 2
spacer length: 53.4
has_exact_synonym: Malamido-PEG12-NHS
has_exact_synonym: NHS-PEG12-Maleimide
has_exact_synonym: SM[PEG]12
has_obo_namespace: XLMOD
id: XLMOD:02158

Axiom
annotated source: Maleimide-PEG12-NHS
annotated property: definition
annotated target: Succinimidyl-[(N-maleimidopropionamido)-dodecaethyleneglycol] ester.
database_cross_reference: CAS:1426151-00-9
database_cross_reference: ChemSpiderID:32055629
database_cross_reference: ChemicalBookNo:CB32750847
database_cross_reference: MDL:MFCD11041148
database_cross_reference: PubChem_Compound:51340947

Maleimide-PEG24-NHS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Succinimidyl-[(N-maleimidopropionamido)-tetracosaethyleneglycol] ester.
hydrophilic PE gchain: 24
reaction sites: 2
spacer length: 95.2
has_exact_synonym: Malamido-PEG24-NHS
has_exact_synonym: NHS-PEG24-Maleimide
has_exact_synonym: SM[PEG]24
has_obo_namespace: XLMOD
id: XLMOD:02159

Axiom
annotated source: Maleimide-PEG24-NHS
annotated property: definition
annotated target: Succinimidyl-[(N-maleimidopropionamido)-tetracosaethyleneglycol] ester.
database_cross_reference: PubChem_Compound:89408683

11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester cross-linker.
hydrophilic PE gchain: 4
reaction sites: 2
spacer length: 15.7
has_exact_synonym: Sulfo-Kmus
has_obo_namespace: XLMOD
id: XLMOD:02160

Axiom
annotated source: 11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester
annotated property: definition
annotated target: 11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester cross-linker.
database_cross_reference: CAS:211236-68-9
database_cross_reference: ChemSpiderID:4243138
database_cross_reference: ChemicalBookNo:CB51025445
database_cross_reference: MDL:MFCD01075057
database_cross_reference: PubChem_Compound:5066232

DTME
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Dithio-bis-maleimidoethane.
reaction sites: 2
spacer length: 13.3
has_exact_synonym: Dithio-bis-maleimidoethane
has_obo_namespace: XLMOD
id: XLMOD:02161

Axiom
annotated source: DTME
annotated property: definition
annotated target: Dithio-bis-maleimidoethane.
database_cross_reference: CAS:71865-37-7
database_cross_reference: ChemSpiderID:166677
database_cross_reference: ChemicalBookNo:CB3134825
database_cross_reference: MDL:MFCD01863385
database_cross_reference: PubChem_Compound:191989

3-N-Maleimidobenzoic Acid N-Succinimidyl Ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 3-N-Maleimidobenzoic Acid N-Succinimidyl Ester cross-linker.
reaction sites: 2
spacer length: 9.9
has_obo_namespace: XLMOD
id: XLMOD:02162

Axiom
annotated source: 3-N-Maleimidobenzoic Acid N-Succinimidyl Ester
annotated property: definition
annotated target: 3-N-Maleimidobenzoic Acid N-Succinimidyl Ester cross-linker.
database_cross_reference: CAS:58626-38-3
database_cross_reference: ChemSpiderID:84714
database_cross_reference: ChemicalBookNo:CB0342553
database_cross_reference: PubChem_Compound:93861

N-Succinimidyl 3-(Bromoacetamido)propionate
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: bromoacetyl
definition: N-Succinimidyl 3-(Bromoacetamido)propionate cross-linker.
reaction sites: 2
spacer length: 6.2
has_obo_namespace: XLMOD
id: XLMOD:02163

Axiom
annotated source: N-Succinimidyl 3-(Bromoacetamido)propionate
annotated property: definition
annotated target: N-Succinimidyl 3-(Bromoacetamido)propionate cross-linker.
database_cross_reference: CAS:57159-62-3
database_cross_reference: ChemSpiderID:3662399
database_cross_reference: ChemicalBookNo:CB1123003
database_cross_reference: PubChem_Compound:4463814

MTS-3-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 1,3-Propanediyl bismethanethiosulfonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02164

Axiom
annotated source: MTS-3-MTS
annotated property: definition
annotated target: 1,3-Propanediyl bismethanethiosulfonate.
database_cross_reference: CAS:55-96-9
database_cross_reference: ChemSpiderID:497206
database_cross_reference: ChemicalBookNo:CB51175454
database_cross_reference: PubChem_Compound:571841

MTS-4-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 1,4-Butanediyl bismethanethiosulfonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02165

Axiom
annotated source: MTS-4-MTS
annotated property: definition
annotated target: 1,4-Butanediyl bismethanethiosulfonate.
database_cross_reference: CAS:55-99-2
database_cross_reference: ChemSpiderID:210759
database_cross_reference: ChemicalBookNo:CB11175456
database_cross_reference: PubChem_Compound:241169

MTS-5-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 1,5-Pentanediyl bismethanethiosulfonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02166

Axiom
annotated source: MTS-5-MTS
annotated property: definition
annotated target: 1,5-Pentanediyl bismethanethiosulfonate.
database_cross_reference: ChemSpiderID:58967

MTS-6-MTS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 1,6-Hexanediyl bismethanethiosulfonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02167

Axiom
annotated source: MTS-6-MTS
annotated property: definition
annotated target: 1,6-Hexanediyl bismethanethiosulfonate.
database_cross_reference: CAS:56-01-9
database_cross_reference: ChemSpiderID:2606746
database_cross_reference: ChemicalBookNo:CB61497498
database_cross_reference: PubChem_Compound:3360826

6-maleimidocaproic acid
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: carboxyl
definition: 6-Maleimidocaproic acid cross-linker.
reaction sites: 2
spacer length: 9.4
has_obo_namespace: XLMOD
id: XLMOD:02168

Axiom
annotated source: 6-maleimidocaproic acid
annotated property: definition
annotated target: 6-Maleimidocaproic acid cross-linker.
database_cross_reference: CAS:55750-53-3
database_cross_reference: ChemSpiderID:498795
database_cross_reference: ChemicalBookNo:CB6300928
database_cross_reference: MDL:MFCD00043140
database_cross_reference: PubChem_Compound:573683

SFAD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: perfluoroaryl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Succinimidyl(perfluoroazidobenzamido)ethyl-1,3´-dithiopropionate.
reaction sites: 2
spacer length: 14.6
has_obo_namespace: XLMOD
id: XLMOD:02169

Axiom
annotated source: SFAD
annotated property: definition
annotated target: Succinimidyl(perfluoroazidobenzamido)ethyl-1,3´-dithiopropionate.
database_cross_reference: ChemSpiderID:30798432
database_cross_reference: ChemicalBookNo:CB9178443
database_cross_reference: PubChem_Compound:90471066

LCABH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: LCABH cross-linker.
reaction sites: 2
spacer length: 14.6
has_obo_namespace: XLMOD
id: XLMOD:02170

Axiom
annotated source: LCABH
annotated property: definition
annotated target: LCABH cross-linker.
database_cross_reference: PSI:XL

NHS-LC-ASA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: iodinatable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
definition: Succinimidyl(4-azido-salicylamido) hexanoate.
reaction sites: 2
spacer length: 18.0
has_exact_synonym: NHS-Long Chain-ASA
has_obo_namespace: XLMOD
id: XLMOD:02171

Axiom
annotated source: NHS-LC-ASA
annotated property: definition
annotated target: Succinimidyl(4-azido-salicylamido) hexanoate.
database_cross_reference: PSI:XL

AEDP-HCl
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
subclass of: Restriction
  on property: has_reactive_group
  some values from: carboxyl
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: 3-([2-Aminoethyl] dithio)-propionic acid hydrochloride.
reaction sites: 2
spacer length: 9.5
has_obo_namespace: XLMOD
id: XLMOD:02172

Axiom
annotated source: AEDP-HCl
annotated property: definition
annotated target: 3-([2-Aminoethyl] dithio)-propionic acid hydrochloride.
database_cross_reference: CAS:351422-31-6
database_cross_reference: ChemSpiderID:4366598
database_cross_reference: ChemicalBookNo:CB11564306

AMAS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-(alpha-Maleimidoacetoxy)-succinimide ester.
reaction sites: 2
spacer length: 4.4
has_obo_namespace: XLMOD
id: XLMOD:02173

Axiom
annotated source: AMAS
annotated property: definition
annotated target: N-(alpha-Maleimidoacetoxy)-succinimide ester.
database_cross_reference: CAS:55750-61-3
database_cross_reference: ChemSpiderID:2547634
database_cross_reference: ChemicalBookNo:CB4326351
database_cross_reference: PubChem_Compound:3299229

BMB
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 1,4-Bis-Maleimidobutane.
reaction sites: 2
spacer length: 10.9
has_obo_namespace: XLMOD
id: XLMOD:02174

Axiom
annotated source: BMB
annotated property: definition
annotated target: 1,4-Bis-Maleimidobutane.
database_cross_reference: CAS:28537-70-4
database_cross_reference: ChemSpiderID:209301
database_cross_reference: ChemicalBookNo:CB4131366
database_cross_reference: PubChem_Compound:239576

BMDB
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: is_cleavable
  some values from: periodate cleavable
definition: 1,4-Bis-Maleimidyl-2,3-dihydroxybutane.
reaction sites: 2
spacer length: 10.2
has_obo_namespace: XLMOD
id: XLMOD:02175

Axiom
annotated source: BMDB
annotated property: definition
annotated target: 1,4-Bis-Maleimidyl-2,3-dihydroxybutane.
database_cross_reference: ChemSpiderID:4222027
database_cross_reference: ChemicalBookNo:CB9370889

BMOE
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Bis-Maleimidoethane.
reaction sites: 2
spacer length: 8.0
has_obo_namespace: XLMOD
id: XLMOD:02176

Axiom
annotated source: BMOE
annotated property: definition
annotated target: Bis-Maleimidoethane.
database_cross_reference: CAS:5132-30-9
database_cross_reference: ChemSpiderID:11359915
database_cross_reference: ChemicalBookNo:CB5476024
database_cross_reference: MDL:MFCD00458699
database_cross_reference: PubChem_Compound:237509

BMPA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: carboxyl
definition: N-beta-Maleimidopropionic acid.
reaction sites: 2
spacer length: 5.9
has_obo_namespace: XLMOD
id: XLMOD:02177

Axiom
annotated source: BMPA
annotated property: definition
annotated target: N-beta-Maleimidopropionic acid.
database_cross_reference: CAS:7423-55-4
database_cross_reference: ChemSpiderID:498738
database_cross_reference: ChemicalBookNo:CB1371466
database_cross_reference: PubChem_Compound:573621

BMPH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: N-(beta-Maleimidopropionic acid)hydrazide.
reaction sites: 2
spacer length: 8.1
has_obo_namespace: XLMOD
id: XLMOD:02178

Axiom
annotated source: BMPH
annotated property: definition
annotated target: N-(beta-Maleimidopropionic acid)hydrazide.
database_cross_reference: CAS:359436-60-5
database_cross_reference: ChemSpiderID:3602748
database_cross_reference: ChemicalBookNo:CB0106874
database_cross_reference: PubChem_Compound:4401583

BM(PEG)2
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 1,8-Bis-Maleimidodiethyleneglycol.
hydrophilic PE gchain: 2
reaction sites: 2
spacer length: 14.7
has_exact_synonym: BM[PEO]2
has_exact_synonym: maleimide-PEG2-maleimide
has_obo_namespace: XLMOD
id: XLMOD:02179

Axiom
annotated source: BM(PEG)2
annotated property: definition
annotated target: 1,8-Bis-Maleimidodiethyleneglycol.
database_cross_reference: CAS:115597-84-7
database_cross_reference: ChemSpiderID:2922525
database_cross_reference: ChemicalBookNo:CB9190751
database_cross_reference: MDL:MFCD01096749
database_cross_reference: PubChem_Compound:3690297

BM(PEG)3
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 1,8-Bis-Maleimidotriethyleneglycol.
hydrophilic PE gchain: 3
reaction sites: 2
spacer length: 17.8
has_exact_synonym: BM[PEO]3
has_exact_synonym: maleimide-PEG3-maleimide
has_obo_namespace: XLMOD
id: XLMOD:02180

Axiom
annotated source: BM(PEG)3
annotated property: definition
annotated target: 1,8-Bis-Maleimidotriethyleneglycol.
database_cross_reference: CAS:86099-06-1
database_cross_reference: ChemSpiderID:2579075
database_cross_reference: ChemicalBookNo:CB9190751
database_cross_reference: PubChem_Compound:3331999

BM(PEG)4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: 1,11-Bis-Maleimidotetraethyleneglycol.
hydrophilic PE gchain: 4
reaction sites: 2
spacer length: 19.9
has_exact_synonym: BM[PEO]4
has_exact_synonym: maleimide-PEG4-maleimide
has_obo_namespace: XLMOD
id: XLMOD:02181

Axiom
annotated source: BM(PEG)4
annotated property: definition
annotated target: 1,11-Bis-Maleimidotetraethyleneglycol.
database_cross_reference: CAS:86099-06-1
database_cross_reference: ChemSpiderID:2579075
database_cross_reference: ChemicalBookNo:CB8506674
database_cross_reference: PubChem_Compound:3331999

C6-SANH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazone
definition: C6-Succinimidyl 4-hydrazinonicotinate acetone hydrazone.
reaction sites: 2
spacer length: 14.4
has_obo_namespace: XLMOD
id: XLMOD:02182
comment: SANH with extended six carbon linker.

Axiom
annotated source: C6-SANH
annotated property: definition
annotated target: C6-Succinimidyl 4-hydrazinonicotinate acetone hydrazone.
database_cross_reference: CAS:937249-76-8
database_cross_reference: ChemicalBookNo:CB9456561

C6-4-SFB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: carbonyl
definition: C6-Succinimidyl 4-formylbenzoate.
reaction sites: 2
spacer length: 13.5
has_obo_namespace: XLMOD
id: XLMOD:02183
comment: SFB with extended six carbon linker.

Axiom
annotated source: C6-4-SFB
annotated property: definition
annotated target: C6-Succinimidyl 4-formylbenzoate.
database_cross_reference: CAS:1005773-18-1
database_cross_reference: ChemicalBookNo:CB0456285

SBAP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: bromoacetyl
definition: Succinimdyl 3-(bromoacetamido)propionate.
reaction sites: 2
spacer length: 6.2
has_obo_namespace: XLMOD
id: XLMOD:02184

Axiom
annotated source: SBAP
annotated property: definition
annotated target: Succinimdyl 3-(bromoacetamido)propionate.
database_cross_reference: CAS:57159-62-3
database_cross_reference: ChemSpiderID:3662399
database_cross_reference: ChemicalBookNo:CB1123003
database_cross_reference: PubChem_Compound:4463814

SFB
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: carbonyl
definition: Succinimidyl 4-formylbenzoate.
reaction sites: 2
spacer length: 5.8
has_obo_namespace: XLMOD
id: XLMOD:02185

Axiom
annotated source: SFB
annotated property: definition
annotated target: Succinimidyl 4-formylbenzoate.
database_cross_reference: CAS:60444-78-2
database_cross_reference: ChemSpiderID:3339198
database_cross_reference: ChemicalBookNo:CB7361809
database_cross_reference: PubChem_Compound:4126130

SHTH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Succinimidyl 4-hydrazidoterephthalate hydrochloride.
reaction sites: 2
spacer length: 7.9
has_obo_namespace: XLMOD
id: XLMOD:02186

Axiom
annotated source: SHTH
annotated property: definition
annotated target: Succinimidyl 4-hydrazidoterephthalate hydrochloride.
database_cross_reference: PSI:XL

Sulfo-KMUS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-(kappa-maleimidoundecanoyloxy)sulfosuccinimide ester.
reaction sites: 2
spacer length: 19.5
has_obo_namespace: XLMOD
id: XLMOD:02187

Axiom
annotated source: Sulfo-KMUS
annotated property: definition
annotated target: N-(kappa-maleimidoundecanoyloxy)sulfosuccinimide ester.
database_cross_reference: CAS:220935-13-7
database_cross_reference: ChemSpiderID:4243138
database_cross_reference: ChemicalBookNo:CB2774516
database_cross_reference: PubChem_Compound:5066232

THPP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: carboxyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxymethyl phosphine
definition: beta-(tris[hydroxymethyl]phosphine)propionic acid.
reaction sites: 2
spacer length: 3.03
has_obo_namespace: XLMOD
id: XLMOD:02188

Axiom
annotated source: THPP
annotated property: definition
annotated target: beta-(tris[hydroxymethyl]phosphine)propionic acid.
database_cross_reference: CAS:15931-64-3
database_cross_reference: ChemSpiderID:3310006
database_cross_reference: ChemicalBookNo:CB2497718
database_cross_reference: PubChem_Compound:4095799

EMCA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: carboxyl
definition: N-epsilon-Maleimidocaproic acid.
reaction sites: 2
spacer length: 9.4
has_obo_namespace: XLMOD
id: XLMOD:02189

Axiom
annotated source: EMCA
annotated property: definition
annotated target: N-epsilon-Maleimidocaproic acid.
database_cross_reference: CAS:55750-53-3
database_cross_reference: ChemSpiderID:2006116
database_cross_reference: ChemicalBookNo:CB6300928
database_cross_reference: PubChem_Compound:573683

HBVS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: vinyl sulfone
definition: 1,6-Hexane-bis-vinylsulfone.
reaction sites: 2
spacer length: 14.7
has_obo_namespace: XLMOD
id: XLMOD:02190

Axiom
annotated source: HBVS
annotated property: definition
annotated target: 1,6-Hexane-bis-vinylsulfone.
database_cross_reference: ChemicalBookNo:CB02711432
database_cross_reference: MDL:MFCD01866933

KMUA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: carboxyl
definition: N-kappa-Maleimidoundecanoic acid.
reaction sites: 2
spacer length: 15.7
has_obo_namespace: XLMOD
id: XLMOD:02191

Axiom
annotated source: KMUA
annotated property: definition
annotated target: N-kappa-Maleimidoundecanoic acid.
database_cross_reference: CAS:57079-01-3
database_cross_reference: ChemSpiderID:3809539
database_cross_reference: ChemicalBookNo:CB41175477
database_cross_reference: PubChem_Compound:4618600

KMUH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_cleavable
  some values from: thiol cleavable
definition: N-(kappa-Maleimidoundecanoic acid)hydrazide.
reaction sites: 2
spacer length: 19.0
has_obo_namespace: XLMOD
id: XLMOD:02192

Axiom
annotated source: KMUH
annotated property: definition
annotated target: N-(kappa-Maleimidoundecanoic acid)hydrazide.
database_cross_reference: CAS:359436-62-7
database_cross_reference: ChemSpiderID:3637842
database_cross_reference: ChemicalBookNo:CB71175478
database_cross_reference: PubChem_Compound:4438236

MPBH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_cleavable
  some values from: thiol cleavable
definition: 4-(4-N-Maleimidophenyl)butyric acid hydrazide-HCl.
reaction sites: 2
spacer length: 17.9
has_obo_namespace: XLMOD
id: XLMOD:02193

Axiom
annotated source: MPBH
annotated property: definition
annotated target: 4-(4-N-Maleimidophenyl)butyric acid hydrazide-HCl.
database_cross_reference: ChemSpiderID:8080402
database_cross_reference: ChemicalBookNo:CB0734136
database_cross_reference: PubChem_Compound:9904748

SANH
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazone
definition: Succinimidyl-2-(m-azido-o-nitrobenzamido)ethyl 1,3'-dithiopropionate.
reaction sites: 2
spacer length: 6.7
has_obo_namespace: XLMOD
id: XLMOD:02194

Axiom
annotated source: SANH
annotated property: definition
annotated target: Succinimidyl-2-(m-azido-o-nitrobenzamido)ethyl 1,3'-dithiopropionate.
database_cross_reference: ChemSpiderID:32034301
database_cross_reference: ChemicalBookNo:CB8354354

SAND-PR
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazone
definition: Sulfosuccinimidyl-2-(m-azido-o-nitrobenzamido)ethyl 1,3'-dithiopropionate.
reaction sites: 2
spacer length: 6.7
has_obo_namespace: XLMOD
id: XLMOD:02195

Axiom
annotated source: SAND-PR
annotated property: definition
annotated target: Sulfosuccinimidyl-2-(m-azido-o-nitrobenzamido)ethyl 1,3'-dithiopropionate.
database_cross_reference: CAS:112820-42-5
database_cross_reference: ChemSpiderID:115619
database_cross_reference: ChemicalBookNo:CB71367710
database_cross_reference: MDL:MFCD02091654

Sulfo-SAPD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
definition: Sulfosuccinimidyl 2-(4-azidosalicylamido) ethyl-1,3-dithioproprioonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02196

Axiom
annotated source: Sulfo-SAPD
annotated property: definition
annotated target: Sulfosuccinimidyl 2-(4-azidosalicylamido) ethyl-1,3-dithioproprioonate.
database_cross_reference: ChemicalBookNo:CB5476059

SAPD
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydroxyphenyl azide
definition: Succinimidyl 2-(4-azidosalicylamido) ethyl-1,3-dithioproprioonate.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02197

Axiom
annotated source: SAPD
annotated property: definition
annotated target: Succinimidyl 2-(4-azidosalicylamido) ethyl-1,3-dithioproprioonate.
database_cross_reference: ChemicalBookNo:CB5476059

BS(PEG)5
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
definition: Bis(sulfosuccinimidyl)suberate pentaethyleneglycol.
bridge formula: C14 H22 O7
hydrophilic PE gchain: 5
mono isotopic mass: 302.13655
reaction sites: 2
spacer length: 21.7
has_exact_synonym: NHS-PEG5-NHS
has_obo_namespace: XLMOD
id: XLMOD:02198

Axiom
annotated source: BS(PEG)5
annotated property: definition
annotated target: Bis(sulfosuccinimidyl)suberate pentaethyleneglycol.
database_cross_reference: CAS:756526-03-1
database_cross_reference: ChemSpiderID:28604877
database_cross_reference: ChemicalBookNo:CB12663893
database_cross_reference: PubChem_Compound:51340935

BS(PEG)9
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
definition: Bis(sulfosuccinimidyl)suberate nonaethyleneglycol.
hydrophilic PE gchain: 9
reaction sites: 2
spacer length: 35.8
has_exact_synonym: NHS-PEG9-NHS
has_obo_namespace: XLMOD
id: XLMOD:02199

Axiom
annotated source: BS(PEG)9
annotated property: definition
annotated target: Bis(sulfosuccinimidyl)suberate nonaethyleneglycol.
database_cross_reference: CAS:1008402-79-6
database_cross_reference: ChemSpiderID:29354490
database_cross_reference: ChemicalBookNo:CB32546994
database_cross_reference: PubChem_Compound:77078480

NHS-azide
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: N-hydroxysuccinimide ester ethane azide.
reaction sites: 2
spacer length: 2.5
has_exact_synonym: Azido-NHS ester
has_obo_namespace: XLMOD
id: XLMOD:02200

Axiom
annotated source: NHS-azide
annotated property: definition
annotated target: N-hydroxysuccinimide ester ethane azide.
database_cross_reference: PSI:XL

NHS-PEG4-azide
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: N-hydroxysuccinimide ester tetraoxapentadecane azide.
hydrophilic PE gchain: 4
reaction sites: 2
spacer length: 18.9
has_exact_synonym: Azido-PEG4-NHS ester
has_obo_namespace: XLMOD
id: XLMOD:02201

Axiom
annotated source: NHS-PEG4-azide
annotated property: definition
annotated target: N-hydroxysuccinimide ester tetraoxapentadecane azide.
database_cross_reference: CAS:944251-24-5
database_cross_reference: ChemSpiderID:28604876
database_cross_reference: ChemicalBookNo:CB72663895
database_cross_reference: PubChem_Compound:51340931

NHS-PEG12-azide
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: N-hydroxysuccinimide ester dodecaoxanonatriacontane azide.
hydrophilic PE gchain: 12
reaction sites: 2
spacer length: 47.3
has_exact_synonym: Azido-PEG12-NHS ester
has_obo_namespace: XLMOD
id: XLMOD:02202

Axiom
annotated source: NHS-PEG12-azide
annotated property: definition
annotated target: N-hydroxysuccinimide ester dodecaoxanonatriacontane azide.
database_cross_reference: CAS:1610796-02-5
database_cross_reference: ChemSpiderID:29354441
database_cross_reference: ChemicalBookNo:CB63062337
database_cross_reference: PubChem_Compound:51340930

SPDP-PEG4-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: 2-pyridyldithiol-tetraoxatetradecane-N-hydroxysuccinimide.
hydrophilic PE gchain: 4
reaction sites: 2
spacer length: 25.7
has_exact_synonym: PEG4-SPDP
has_obo_namespace: XLMOD
id: XLMOD:02203

Axiom
annotated source: SPDP-PEG4-NHS ester
annotated property: definition
annotated target: 2-pyridyldithiol-tetraoxatetradecane-N-hydroxysuccinimide.
database_cross_reference: CAS:1334177-95-5
database_cross_reference: ChemSpiderID:29354407
database_cross_reference: ChemicalBookNo:CB83163140
database_cross_reference: PubChem_Compound:77078429

SPDP-PEG12-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: 2-pyridyldithiol-tetraoxaoctatriacontane-N-hydroxysuccinimide.
hydrophilic PE gchain: 12
reaction sites: 2
spacer length: 54.1
has_exact_synonym: PEG12-SPDP
has_obo_namespace: XLMOD
id: XLMOD:02204

Axiom
annotated source: SPDP-PEG12-NHS ester
annotated property: definition
annotated target: 2-pyridyldithiol-tetraoxaoctatriacontane-N-hydroxysuccinimide.
database_cross_reference: ChemicalBookNo:CB53163134
database_cross_reference: PubChem_Compound:51341026

BPM
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
definition: 4-(N-Maleimido)benzophenone.
reaction sites: 2
has_exact_synonym: Benzophenone-4-maleimide
has_obo_namespace: XLMOD
id: XLMOD:02205

Axiom
annotated source: BPM
annotated property: definition
annotated target: 4-(N-Maleimido)benzophenone.
database_cross_reference: CAS:92944-71-3
database_cross_reference: ChemSpiderID:129121
database_cross_reference: ChemicalBookNo:CB6293028
database_cross_reference: MDL:MFCD00079465
database_cross_reference: PubChem_Compound:24897368

TPAL
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: carbonyl
definition: 1,4-Phthalaldehyde.
bridge formula: C8 H6
mono isotopic mass: 102.04695021
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02206

Axiom
annotated source: TPAL
annotated property: definition
annotated target: 1,4-Phthalaldehyde.
database_cross_reference: CAS:623-27-8
database_cross_reference: ChemSpiderID:11673
database_cross_reference: ChemicalBookNo:CB1425781
database_cross_reference: PubChem_Compound:12173

DEB
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: carbonyl
definition: Diformyl-5-ethynylbenzene.
bridge formula: C10 H6
mono isotopic mass: 126.04695021
reaction sites: 2
has_exact_synonym: 4-Ethynylphthalaldehyde
has_obo_namespace: XLMOD
id: XLMOD:02207

Axiom
annotated source: DEB
annotated property: definition
annotated target: Diformyl-5-ethynylbenzene.
database_cross_reference: ChemSpiderID:26667536

DMTMM
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: dimethylether
definition: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02208

Axiom
annotated source: DMTMM
annotated property: definition
annotated target: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride.
database_cross_reference: CAS:3945-69-5
database_cross_reference: ChemSpiderID:2015817
database_cross_reference: ChemicalBookNo:CB5695021
database_cross_reference: PMID:24938783
database_cross_reference: PubChem_Compound:2734059

PDH
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: Pimelic acid dihydrazide.
bridge formula: C7 H12 N4
mono isotopic mass: 152.10619642
reaction sites: 2
has_exact_synonym: Heptanedihydrazide
has_obo_namespace: XLMOD
id: XLMOD:02209

Axiom
annotated source: PDH
annotated property: definition
annotated target: Pimelic acid dihydrazide.
database_cross_reference: CAS:13043-98-6
database_cross_reference: ChemSpiderID:250842
database_cross_reference: ChemicalBookNo:CB9261011
database_cross_reference: PubChem_Compound:284646

PDH-d10
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled pimelic acid dihydrazide.
bridge formula: C7 D10 H2 N4
doublet delta mass: 10.06276744
mono isotopic mass: 162.16896386
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02210

Axiom
annotated source: PDH-d10
annotated property: definition
annotated target: Deuterium labelled pimelic acid dihydrazide.
database_cross_reference: PSI:XL

ABAS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Azidobenzoic acid succinimide.
reaction sites: 2
spacer length: 7.0
has_obo_namespace: XLMOD
id: XLMOD:02211

Axiom
annotated source: ABAS
annotated property: definition
annotated target: Azidobenzoic acid succinimide.
database_cross_reference: CAS:53053-08-0
database_cross_reference: ChemSpiderID:108951
database_cross_reference: ChemicalBookNo:CB5187007
database_cross_reference: PMID:25192908
database_cross_reference: PubChem_Compound:122153

ABAS-13C6
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
definition: 13C labelled azidobenzoic acid succinimide.
doublet delta mass: 6.02016
reaction sites: 2
spacer length: 7.0
has_obo_namespace: XLMOD
id: XLMOD:02212

Axiom
annotated source: ABAS-13C6
annotated property: definition
annotated target: 13C labelled azidobenzoic acid succinimide.
database_cross_reference: PMID:25192908

CBS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
definition: Carboxy-benzophenone-succinimide.
reaction sites: 2
spacer length: 7.0
has_obo_namespace: XLMOD
id: XLMOD:02213

Axiom
annotated source: CBS
annotated property: definition
annotated target: Carboxy-benzophenone-succinimide.
database_cross_reference: PMID:25192908

CBS-13C6
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
definition: 13C labelled carboxy-benzophenone-succinimide.
doublet delta mass: 6.02016
reaction sites: 2
spacer length: 7.0
has_obo_namespace: XLMOD
id: XLMOD:02214

Axiom
annotated source: CBS-13C6
annotated property: definition
annotated target: 13C labelled carboxy-benzophenone-succinimide.
database_cross_reference: PMID:25192908

SDA-13C5
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: diazirine
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
definition: 13C labelled succinimidyl-ester diazirine.
bridge formula: 13C5 H6 O1
doublet delta mass: 5.0168
mono isotopic mass: 87.05866484
reaction sites: 2
spacer length: 5.0
has_obo_namespace: XLMOD
id: XLMOD:02215

Axiom
annotated source: SDA-13C5
annotated property: definition
annotated target: 13C labelled succinimidyl-ester diazirine.
database_cross_reference: PMID:25192908

DMDSSO
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable C-S bond
definition: Dimethyl disuccinimidyl sulfoxide.
reaction sites: 2
has_exact_synonym: DMDSSO-d0
has_obo_namespace: XLMOD
id: XLMOD:02216

Axiom
annotated source: DMDSSO
annotated property: definition
annotated target: Dimethyl disuccinimidyl sulfoxide.
database_cross_reference: PMID:24471733
database_cross_reference: PMID:27417384

DMDSSO-d10
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable C-S bond
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled dimethyl disuccinimidyl sulfoxide.
doublet delta mass: 10.06276744
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02217

Axiom
annotated source: DMDSSO-d10
annotated property: definition
annotated target: Deuterium labelled dimethyl disuccinimidyl sulfoxide.
database_cross_reference: PMID:24471733

ICATXL1
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: N-biotinyl-N'-[3,5-Bis-(N-succinimidyloxycarbonyl-methoxy)-benzoyl]-ethane-1,2-diamine.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02218

Axiom
annotated source: ICATXL1
annotated property: definition
annotated target: N-biotinyl-N'-[3,5-Bis-(N-succinimidyloxycarbonyl-methoxy)-benzoyl]-ethane-1,2-diamine.
database_cross_reference: PMID:16895390

ICATXL2
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: S-S-biotinyl-N'-[3,5-Bis-(N-succinimidyloxycarbonyl-methoxy)-benzoyl]-ethane-1,2-diamine.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02219

Axiom
annotated source: ICATXL2
annotated property: definition
annotated target: S-S-biotinyl-N'-[3,5-Bis-(N-succinimidyloxycarbonyl-methoxy)-benzoyl]-ethane-1,2-diamine.
database_cross_reference: PMID:16895390

SSTN
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: nitrobenzylester
definition: Succinic acid succinimidyl ester 5-thioyloxy-2-nitrobenzyl ester.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02220

Axiom
annotated source: SSTN
annotated property: definition
annotated target: Succinic acid succinimidyl ester 5-thioyloxy-2-nitrobenzyl ester.
database_cross_reference: PMID:15366956

SCNE
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
subclass of: Restriction
  on property: is_cleavable
  some values from: photocleavable
definition: Di 6-(3-succinimidyl carbonyloxymethyl-4-nitro-phenoxy)-hexanoic acid disulfide diethanol ester.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02221

Axiom
annotated source: SCNE
annotated property: definition
annotated target: Di 6-(3-succinimidyl carbonyloxymethyl-4-nitro-phenoxy)-hexanoic acid disulfide diethanol ester.
database_cross_reference: PMID:22432929

azide-A-DSBSO
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable by MS2 labile bond
subclass of: Restriction
  on property: is_cleavable
  some values from: acid cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable C-S bond
definition: Azide-tagged acid-cleavable disuccinimidyl-bissulfoxide.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02222

Axiom
annotated source: azide-A-DSBSO
annotated property: definition
annotated target: Azide-tagged acid-cleavable disuccinimidyl-bissulfoxide.
database_cross_reference: PMID:25253489
database_cross_reference: PMID:25823605
database_cross_reference: PMID:27417384

alkyne-A-DSBSO
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: alkyne
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: acid cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable C-S bond
definition: Alkyne-tagged acid-cleavable disuccinimidyl-bissulfoxide.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02223

Axiom
annotated source: alkyne-A-DSBSO
annotated property: definition
annotated target: Alkyne-tagged acid-cleavable disuccinimidyl-bissulfoxide.
database_cross_reference: PMID:25823605
database_cross_reference: PMID:29537042

IML 3
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Identical mass linker 3.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02224

Axiom
annotated source: IML 3
annotated property: definition
annotated target: Identical mass linker 3.
database_cross_reference: PMID:26269432

SuVP
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Disuccinimidyl-succinamyl-valyl-proline.
reaction sites: 2
spacer length: 11.2
has_obo_namespace: XLMOD
id: XLMOD:02225

Axiom
annotated source: SuVP
annotated property: definition
annotated target: Disuccinimidyl-succinamyl-valyl-proline.
database_cross_reference: PMID:20560670
database_cross_reference: PMID:26091612

DHSO
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable C-S bond
definition: Dihydrazide sulfoxide.
reaction sites: 2
spacer length: 12.4
has_exact_synonym: 3,3'-sulfinyldi(propanehydrazide)
has_obo_namespace: XLMOD
id: XLMOD:02226

Axiom
annotated source: DHSO
annotated property: definition
annotated target: Dihydrazide sulfoxide.
database_cross_reference: PMID:27417384

PL
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: photocleavable
CID fragment: 122.06
definition: Photo-cleavable Leiker.
mono isotopic mass: 316.14
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02227

Axiom
annotated source: PL
annotated property: definition
annotated target: Photo-cleavable Leiker.
database_cross_reference: PMID:26952210
database_cross_reference: PMID:27734140

PEG-PL
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: photocleavable
definition: Polyethylene glycol photo-cleavable Leiker.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02228

Axiom
annotated source: PEG-PL
annotated property: definition
annotated target: Polyethylene glycol photo-cleavable Leiker.
database_cross_reference: PMID:26952210

Sulfo-PL
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: photocleavable
definition: Sulfo-photo-cleavable Leiker.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02229

Axiom
annotated source: Sulfo-PL
annotated property: definition
annotated target: Sulfo-photo-cleavable Leiker.
database_cross_reference: PMID:26952210

bAL1
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: chemically cleavable
definition: Biotinylated azo-Leiker 1 with an azobenzene-based chemical cleavage site.
reaction sites: 2
spacer length: 9.3
has_obo_namespace: XLMOD
id: XLMOD:02230

Axiom
annotated source: bAL1
annotated property: definition
annotated target: Biotinylated azo-Leiker 1 with an azobenzene-based chemical cleavage site.
database_cross_reference: PMID:26952210

bAL2
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: chemically cleavable
definition: Biotinylated azo-Leiker 2 with an azobenzene-based chemical cleavage site.
reaction sites: 2
spacer length: 9.3
has_obo_namespace: XLMOD
id: XLMOD:02231

Axiom
annotated source: bAL2
annotated property: definition
annotated target: Biotinylated azo-Leiker 2 with an azobenzene-based chemical cleavage site.
database_cross_reference: PMID:26952210

bAL2-d6
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: chemically cleavable
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled biotinylated azo-Leiker 2 with an azobenzene-based chemical cleavage site.
reaction sites: 2
spacer length: 9.3
has_obo_namespace: XLMOD
id: XLMOD:02232

Axiom
annotated source: bAL2-d6
annotated property: definition
annotated target: Deuterium labelled biotinylated azo-Leiker 2 with an azobenzene-based chemical cleavage site.
database_cross_reference: PMID:26952210

BS3-18O2
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: 18O labelled
definition: 18O labelled (bis(sulfosuccinimidyl) 2,2,7,7-suberate).
reaction sites: 2
spacer length: 11.4
has_obo_namespace: XLMOD
id: XLMOD:02233

Axiom
annotated source: BS3-18O2
annotated property: definition
annotated target: 18O labelled (bis(sulfosuccinimidyl) 2,2,7,7-suberate).
database_cross_reference: PMID:14592499

PIR-I
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Protein Interaction Reporter-I.
bridge formula: C6 H10 O2 N1
hydrophilic PE gchain: 3
mono isotopic mass: 128.0712
reaction sites: 2
reporter mass: 555.2481
has_obo_namespace: XLMOD
id: XLMOD:02234

Axiom
annotated source: PIR-I
annotated property: definition
annotated target: Protein Interaction Reporter-I.
database_cross_reference: PMID:17269728

PIR-II
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Protein Interaction Reporter-II.
bridge formula: C4 H6 O2 N1
hydrophilic PE gchain: 3
mono isotopic mass: 100.0399
reaction sites: 2
reporter mass: 1324.5937
has_obo_namespace: XLMOD
id: XLMOD:02235

Axiom
annotated source: PIR-II
annotated property: definition
annotated target: Protein Interaction Reporter-II.
database_cross_reference: PMID:17269728

PIR-III
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: photo cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Protein Interaction Reporter-III.
bridge formula: C4 H6 O2 N1
hydrophilic PE gchain: 3
mono isotopic mass: 100.0399
reaction sites: 2
reporter mass: 1604.6996
has_obo_namespace: XLMOD
id: XLMOD:02236

Axiom
annotated source: PIR-III
annotated property: definition
annotated target: Protein Interaction Reporter-III.
database_cross_reference: PMID:17269728

PIR
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
CID fragment: 711.4
definition: Protein Interaction Reporter.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02237

Axiom
annotated source: PIR
annotated property: definition
annotated target: Protein Interaction Reporter.
database_cross_reference: PMID:15623310

pcPIR
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: photo cleavable
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
CID fragment: 711.4
definition: Photo-cleavable Protein Interaction Reporter.
reaction sites: 2
spacer length: 40.0
has_obo_namespace: XLMOD
id: XLMOD:02238

Axiom
annotated source: pcPIR
annotated property: definition
annotated target: Photo-cleavable Protein Interaction Reporter.
database_cross_reference: PMID:20373789

PEG5-Biotin-Dimer
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: tetrafluorophenyl azide
definition: PEG5-Biotin-Dimer for crosslinking avidin molecules.
hydrophilic PE gchain: 5
reaction sites: 2
spacer length: 43.4
has_obo_namespace: XLMOD
id: XLMOD:02239

Axiom
annotated source: PEG5-Biotin-Dimer
annotated property: definition
annotated target: PEG5-Biotin-Dimer for crosslinking avidin molecules.
database_cross_reference: PSI:XL

Azido-PEG3-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
hydrophilic PE gchain: 3
reaction sites: 2
has_exact_synonym: NHS-PEG3-azide
has_obo_namespace: XLMOD
id: XLMOD:02240

Axiom
annotated source: Azido-PEG3-NHS ester
annotated property: definition
database_cross_reference: CAS:1245718-89-1
database_cross_reference: ChemSpiderID:29354443
database_cross_reference: ChemicalBookNo:CB83062351
database_cross_reference: PubChem_Compound:77078451

Azido-PEG5-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: 1-[(1-Azido-18-oxo-3,6,9,12,15-pentaoxaoctadecan-18-yl)oxy]-2,5-pyrrolidinedione.
hydrophilic PE gchain: 5
reaction sites: 2
has_exact_synonym: NHS-PEG5-azide
has_obo_namespace: XLMOD
id: XLMOD:02241

Axiom
annotated source: Azido-PEG5-NHS ester
annotated property: definition
annotated target: 1-[(1-Azido-18-oxo-3,6,9,12,15-pentaoxaoctadecan-18-yl)oxy]-2,5-pyrrolidinedione.
database_cross_reference: CAS:1433996-86-1
database_cross_reference: ChemSpiderID:29354411
database_cross_reference: ChemicalBookNo:CB23062364
database_cross_reference: PubChem_Compound:77078433

Azido-PEG6-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: 1-[(1-Azido-21-oxo-3,6,9,12,15,18-hexaoxahenicosan-21-yl)oxy]-2,5-pyrrolidinedione.
hydrophilic PE gchain: 6
reaction sites: 2
has_exact_synonym: NHS-PEG6-azide
has_obo_namespace: XLMOD
id: XLMOD:02242

Axiom
annotated source: Azido-PEG6-NHS ester
annotated property: definition
annotated target: 1-[(1-Azido-21-oxo-3,6,9,12,15,18-hexaoxahenicosan-21-yl)oxy]-2,5-pyrrolidinedione.
database_cross_reference: CAS:2055014-64-5
database_cross_reference: ChemSpiderID:29354488
database_cross_reference: ChemicalBookNo:CB43162882
database_cross_reference: PubChem_Compound:77078479

Azido-PEG8-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: 1-[(1-Azido-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-yl)oxy]-2,5-pyrrolidinedione.
hydrophilic PE gchain: 8
reaction sites: 2
has_exact_synonym: NHS-PEG8-azide
has_obo_namespace: XLMOD
id: XLMOD:02243

Axiom
annotated source: Azido-PEG8-NHS ester
annotated property: definition
annotated target: 1-[(1-Azido-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-yl)oxy]-2,5-pyrrolidinedione.
database_cross_reference: CAS:1204834-00-3
database_cross_reference: ChemSpiderID:29354442
database_cross_reference: ChemicalBookNo:CB53062370
database_cross_reference: PubChem_Compound:51340932

Azido-PEG10-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Azido-PEG10-NHS ester.
hydrophilic PE gchain: 10
reaction sites: 2
has_exact_synonym: NHS-PEG10-azide
has_obo_namespace: XLMOD
id: XLMOD:02244

Axiom
annotated source: Azido-PEG10-NHS ester
annotated property: definition
annotated target: Azido-PEG10-NHS ester.
database_cross_reference: PubChem_Compound:134159750

Azido-PEG16-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Azido-PEG16-NHS ester.
hydrophilic PE gchain: 16
reaction sites: 2
has_exact_synonym: NHS-PEG16-azide
has_obo_namespace: XLMOD
id: XLMOD:02245

Axiom
annotated source: Azido-PEG16-NHS ester
annotated property: definition
annotated target: Azido-PEG16-NHS ester.
database_cross_reference: PubChem_Compound:126480441

Azido-PEG24-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Azido-PEG24-NHS ester.
hydrophilic PE gchain: 24
reaction sites: 2
has_exact_synonym: NHS-PEG24-azide
has_obo_namespace: XLMOD
id: XLMOD:02246

Axiom
annotated source: Azido-PEG24-NHS ester
annotated property: definition
annotated target: Azido-PEG24-NHS ester.
database_cross_reference: PubChem_Compound:126480440

SPDP-PEG24-NHS ester
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: pyridinyldisulfide
definition: 2,5-Dioxocyclopentyl 77-oxo-79-(2-pyridinyldisulfanyl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73-tetracosaoxa-76-azanonaheptacontan-1-oate.
hydrophilic PE gchain: 24
reaction sites: 2
has_exact_synonym: PEG24-SPDP
has_obo_namespace: XLMOD
id: XLMOD:02247

Axiom
annotated source: SPDP-PEG24-NHS ester
annotated property: definition
annotated target: 2,5-Dioxocyclopentyl 77-oxo-79-(2-pyridinyldisulfanyl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73-tetracosaoxa-76-azanonaheptacontan-1-oate.
database_cross_reference: ChemSpiderID:32055782
database_cross_reference: ChemicalBookNo:CB13163136
database_cross_reference: PubChem_Compound:77078309

S-Methyl 5,5'-thiodipentanoylhydroxysuccinimide
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: S-Methyl 5,5'-thiodipentanoylhydroxysuccinimide cross-linker.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02248

Axiom
annotated source: S-Methyl 5,5'-thiodipentanoylhydroxysuccinimide
annotated property: definition
annotated target: S-Methyl 5,5'-thiodipentanoylhydroxysuccinimide cross-linker.
database_cross_reference: PMID:19551991

Sulfo-SBP
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
subclass of: Restriction
  on property: is_activatable
  some values from: photoactivatable
definition: 4-(N-Sulfosuccinimidylcarboxy)benzophenone.
reaction sites: 2
specificities: (K,S,T,Y,Protein N-term)
has_obo_namespace: XLMOD
id: XLMOD:02249

Axiom
annotated source: Sulfo-SBP
annotated property: definition
annotated target: 4-(N-Sulfosuccinimidylcarboxy)benzophenone.
database_cross_reference: CAS:91990-88-4
database_cross_reference: PMID:28430416

CBSS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzophenone
definition: Carboxybenzophenonesulfosuccinimide.
reaction sites: 2
has_obo_namespace: XLMOD
id: XLMOD:02250

Axiom
annotated source: CBSS
annotated property: definition
annotated target: Carboxybenzophenonesulfosuccinimide.
database_cross_reference: PMID:31045356

MC4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: 1,4-bis(4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)-1,4-diazabicyclo[2.2.2]octane-1,4-diium.
reaction sites: 2
spacer length: 13.0
has_obo_namespace: XLMOD
id: XLMOD:02251

Axiom
annotated source: MC4
annotated property: definition
annotated target: 1,4-bis(4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)-1,4-diazabicyclo[2.2.2]octane-1,4-diium.
database_cross_reference: PMID:29537042
database_cross_reference: PMID:31045356

PAC4
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: PAC4 cross-linker.
reaction sites: 2
spacer length: 13.0
has_obo_namespace: XLMOD
id: XLMOD:02252

Axiom
annotated source: PAC4
annotated property: definition
annotated target: PAC4 cross-linker.
database_cross_reference: PMID:29537042

cliXLink
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: alkyne
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: cliXLink cross-linker.
reaction sites: 2
spacer length: 9.2
has_obo_namespace: XLMOD
id: XLMOD:02253

Axiom
annotated source: cliXLink
annotated property: definition
annotated target: cliXLink cross-linker.
database_cross_reference: PMID:31593346

ARGO1
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenylglyoxal
definition: R-R aromatic glyoxal cross-linker 1.
hydrophilic PE gchain: 1
mono isotopic mass: 326.079
reaction sites: 2
spacer length: 29.4
has_obo_namespace: XLMOD
id: XLMOD:02254

Axiom
annotated source: ARGO1
annotated property: definition
annotated target: R-R aromatic glyoxal cross-linker 1.
database_cross_reference: PMID:31477730

ARGO2
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenylglyoxal
definition: R-R aromatic glyoxal cross-linker 2.
hydrophilic PE gchain: 2
mono isotopic mass: 370.105
reaction sites: 2
spacer length: 33.7
has_obo_namespace: XLMOD
id: XLMOD:02255

Axiom
annotated source: ARGO2
annotated property: definition
annotated target: R-R aromatic glyoxal cross-linker 2.
database_cross_reference: PMID:31477730

ARGO3
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenylglyoxal
definition: R-R aromatic glyoxal cross-linker 3.
hydrophilic PE gchain: 3
mono isotopic mass: 414.131
reaction sites: 2
spacer length: 37.7
has_obo_namespace: XLMOD
id: XLMOD:02256

Axiom
annotated source: ARGO3
annotated property: definition
annotated target: R-R aromatic glyoxal cross-linker 3.
database_cross_reference: PMID:31477730

KARGO
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenylglyoxal
subclass of: Restriction
  on property: has_reactive_group
  some values from: Ortho-phthalaldehyde
definition: K-R aromatic glyoxal cross-linker.
mono isotopic mass: 352.095
reaction sites: 2
spacer length: 54.1
has_obo_namespace: XLMOD
id: XLMOD:02257

Axiom
annotated source: KARGO
annotated property: definition
annotated target: K-R aromatic glyoxal cross-linker.
database_cross_reference: PMID:31477730

PhoX
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: phosphonic acid
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: PhoX cross-linker.
bridge formula: C8 H3 O5 P1
mono isotopic mass: 209.97181
reaction sites: 2
max spacer length: 20.0
min spacer length: 5.0
has_obo_namespace: XLMOD
id: XLMOD:02258

Axiom
annotated source: PhoX
annotated property: definition
annotated target: PhoX cross-linker.
database_cross_reference: PMID:31477730

CBDPS
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_property
  some values from: hydrophilic
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Cyanurbiotindipropionylsuccinimide.
bridge formula: C19 H23 N7 O4 S3
mono isotopic mass: 509.09682
reaction sites: 3
spacer length: 14.0
has_obo_namespace: XLMOD
id: XLMOD:03001

Axiom
annotated source: CBDPS
annotated property: definition
annotated target: Cyanurbiotindipropionylsuccinimide.
database_cross_reference: PMID:20622150

Sulfo-SBED
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: Sulfo NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Sulfo-SBED cross-linker.
mono isotopic mass: 634.207
reaction sites: 3
spacer length: 13.7
spacer length: 19.1
spacer length: 9.1
has_exact_synonym: Sulfo-N-hydroxysuccinimidyl-2-(6-[biotinamido]-2-(p-azido benzamido)-hexanoamido) ethyl-1,3'-dithioproprionate
has_obo_namespace: XLMOD
id: XLMOD:03002

Axiom
annotated source: Sulfo-SBED
annotated property: definition
annotated target: Sulfo-SBED cross-linker.
database_cross_reference: ChemicalBookNo:CB2771737
database_cross_reference: PMID:15144972
database_cross_reference: PMID:16246579
database_cross_reference: PubChem_Compound:101089650

Mts-Atf-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: tetrafluorophenyl azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: 2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethylmethanethiosulfate.
reaction sites: 3
spacer length: 11.1
spacer length: 29.3
spacer length: 30.7
has_exact_synonym: tetrafluorobenzoyl-biotinamidocaproyl-methanethiosulfonate
has_obo_namespace: XLMOD
id: XLMOD:03003

Axiom
annotated source: Mts-Atf-Biotin
annotated property: definition
annotated target: 2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethylmethanethiosulfate.
database_cross_reference: CAS:1356383-18-0
database_cross_reference: ChemSpiderID:48058836
database_cross_reference: ChemicalBookNo:CB4994943
database_cross_reference: PubChem_Compound:57370043

Mts-Atf-LC-Biotin
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: tetrafluorophenyl azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
definition: 2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]}ethylmethanethiosulfate.
reaction sites: 3
spacer length: 11.1
spacer length: 29.3
spacer length: 30.7
has_exact_synonym: Mts-Atf-Long Chain-Biotin
has_obo_namespace: XLMOD
id: XLMOD:03004

Axiom
annotated source: Mts-Atf-LC-Biotin
annotated property: definition
annotated target: 2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]}ethylmethanethiosulfate.
database_cross_reference: PSI:XL

TSAT
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: Tris-succinimidyl aminotriacetate.
reaction sites: 3
spacer length: 4.2
has_obo_namespace: XLMOD
id: XLMOD:03005

Axiom
annotated source: TSAT
annotated property: definition
annotated target: Tris-succinimidyl aminotriacetate.
database_cross_reference: CAS:401514-72-5
database_cross_reference: ChemSpiderID:3363127
database_cross_reference: ChemicalBookNo:CB8454500
database_cross_reference: MDL:MFCD02258953
database_cross_reference: PubChem_Compound:4150925

SBED
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: phenyl azide
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: SBED cross-linker.
reaction sites: 3
spacer length: 13.7
spacer length: 19.1
spacer length: 9.1
has_exact_synonym: N-hydroxysuccinimidyl-2-(6-[biotinamido]-2-(p-azido benzamido)-hexanoamido) ethyl-1,3'-dithioproprionate
has_obo_namespace: XLMOD
id: XLMOD:03006

Axiom
annotated source: SBED
annotated property: definition
annotated target: SBED cross-linker.
database_cross_reference: PSI:XL

TMEA
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Tris-(2-maleimidoethyl)amine.
reaction sites: 3
spacer length: 10.3
has_obo_namespace: XLMOD
id: XLMOD:03007

Axiom
annotated source: TMEA
annotated property: definition
annotated target: Tris-(2-maleimidoethyl)amine.
database_cross_reference: CAS:139112-38-2
database_cross_reference: ChemSpiderID:8153010
database_cross_reference: ChemicalBookNo:CB8193391
database_cross_reference: MDL:MFCD01868689
database_cross_reference: PubChem_Compound:9977418

TRICEPS
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazone
subclass of: Restriction
  on property: is_cleavable
  some values from: periodate cleavable
definition: TRICEPS cross-linker.
reaction sites: 3
has_obo_namespace: XLMOD
id: XLMOD:03008

Axiom
annotated source: TRICEPS
annotated property: definition
annotated target: TRICEPS cross-linker.
database_cross_reference: PMID:23051814
database_cross_reference: PubChem_Compound:72663594

NNP9
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: NNP9 cross-linker.
bridge formula: C7 D10 H2 N4
mono isotopic mass: 314.1127
reaction sites: 3
spacer length: 10.0
has_obo_namespace: XLMOD
id: XLMOD:03009

Axiom
annotated source: NNP9
annotated property: definition
annotated target: NNP9 cross-linker.
database_cross_reference: PMID:25522193

TATA
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
definition: 2,4,6-triazido-1,3,5-triazine.
mono isotopic mass: 200.05
reaction sites: 3
spacer length: 5.0
has_exact_synonym: Cyanuric triazide
has_obo_namespace: XLMOD
id: XLMOD:03010

Axiom
annotated source: TATA
annotated property: definition
annotated target: 2,4,6-triazido-1,3,5-triazine.
database_cross_reference: CAS:5637-83-2
database_cross_reference: ChemSpiderID:20543
database_cross_reference: ChemicalBookNo:CB82442831
database_cross_reference: PMID:26931439
database_cross_reference: PubChem_Compound:21857

TATA-13C6
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
definition: 13C labelled 2,4,6-triazido-1,3,5-triazine.
doublet delta mass: 6.02016
mono isotopic mass: 206.07016
reaction sites: 3
spacer length: 5.0
has_obo_namespace: XLMOD
id: XLMOD:03011

Axiom
annotated source: TATA-13C6
annotated property: definition
annotated target: 13C labelled 2,4,6-triazido-1,3,5-triazine.
database_cross_reference: PMID:26931439

MRN
type: Class
subclass of: heterofunctional cross-linker
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
definition: MRN cross-linker.
reaction sites: 3
spacer length: 11.4
spacer length: 40.0
spacer length: 6.4
has_obo_namespace: XLMOD
id: XLMOD:03012

Axiom
annotated source: MRN
annotated property: definition
annotated target: MRN cross-linker.
database_cross_reference: PMID:18303833

Mts-Atf-Biotin-LC
type: Class
subclass of: label transfer reagent
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: tetrafluorophenyl azide
subclass of: Restriction
  on property: has_reactive_group
  some values from: methanethiosulfonate
subclass of: Restriction
  on property: is_cleavable
  some values from: cleavable S-S bond
definition: Long chain Mts-Atf-Biotin.
reaction sites: 3
has_obo_namespace: XLMOD
id: XLMOD:03013

Axiom
annotated source: Mts-Atf-Biotin-LC
annotated property: definition
annotated target: Long chain Mts-Atf-Biotin.
database_cross_reference: PSI:XL

DADPS linker
type: Class
subclass of: label transfer reagent
subclass of: formic acid cleavable
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
definition: Linker containing a dialkoxydiphenylsilane group.
reaction sites: 2
specificities: (C,U)
has_obo_namespace: XLMOD
id: XLMOD:03014

Axiom
annotated source: DADPS linker
annotated property: definition
annotated target: Linker containing a dialkoxydiphenylsilane group.
database_cross_reference: PMID:31430117

AZO linker
type: Class
subclass of: label transfer reagent
subclass of: sodium dithionite cleavable
subclass of: Restriction
  on property: has_handle
  some values from: biotin
subclass of: Restriction
  on property: has_reactive_group
  some values from: azide
definition: Linker containing a azobenzene group.
reaction sites: 2
specificities: (C,U)
has_obo_namespace: XLMOD
id: XLMOD:03015

Axiom
annotated source: AZO linker
annotated property: definition
annotated target: Linker containing a azobenzene group.
database_cross_reference: PMID:31430117

derivatization entity
type: Class
subclass of: Restriction
  on property: part_of
  some values from: Proteomics Standards Initiative cross-linking and derivatization controlled vocabulary
definition: Entity relevant to the domain of derivatization in chromatography.
has_obo_namespace: XLMOD
id: XLMOD:06000

Axiom
annotated source: derivatization entity
annotated property: definition
annotated target: Entity relevant to the domain of derivatization in chromatography.
database_cross_reference: PSI:XL

GCMS derivatization reagent
type: Class
subclass of: derivatization entity
definition: Chemical reagent, which transforms a polar group in a molecule into a non-polar group in order to make the molecule volatile and analyzable by GC-MS.
has_obo_namespace: XLMOD
id: XLMOD:06001

Axiom
annotated source: GCMS derivatization reagent
annotated property: definition
annotated target: Chemical reagent, which transforms a polar group in a molecule into a non-polar group in order to make the molecule volatile and analyzable by GC-MS.
database_cross_reference: PSI:XL

alkylation reagent
type: Class
subclass of: GCMS derivatization reagent
definition: Derivatization reagent replacing an active hydrogen by an aliphatic or aliphatic-aromatic group.
has_obo_namespace: XLMOD
id: XLMOD:06002

Axiom
annotated source: alkylation reagent
annotated property: definition
annotated target: Derivatization reagent replacing an active hydrogen by an aliphatic or aliphatic-aromatic group.
database_cross_reference: PSI:XL

silylation reagent
type: Class
subclass of: GCMS derivatization reagent
definition: Silylation reagent replacing an active hydrogen by a silyl group.
has_obo_namespace: XLMOD
id: XLMOD:06003

Axiom
annotated source: silylation reagent
annotated property: definition
annotated target: Silylation reagent replacing an active hydrogen by a silyl group.
database_cross_reference: PSI:XL

acylation reagent
type: Class
subclass of: GCMS derivatization reagent
definition: Acylation reagent replacing an active hydrogen by a acyl (R-C=O-) group.
has_obo_namespace: XLMOD
id: XLMOD:06004

Axiom
annotated source: acylation reagent
annotated property: definition
annotated target: Acylation reagent replacing an active hydrogen by a acyl (R-C=O-) group.
database_cross_reference: PSI:XL

fluorinated anhydride reagent
type: Class
subclass of: acylation reagent
definition: Fluorinated anhydride derivatization reagent.
has_obo_namespace: XLMOD
id: XLMOD:06005

Axiom
annotated source: fluorinated anhydride reagent
annotated property: definition
annotated target: Fluorinated anhydride derivatization reagent.
database_cross_reference: PSI:XL

fluoracylimidazole reagent
type: Class
subclass of: acylation reagent
definition: Fluoracylimidazole derivatization reagent.
has_obo_namespace: XLMOD
id: XLMOD:06006

Axiom
annotated source: fluoracylimidazole reagent
annotated property: definition
annotated target: Fluoracylimidazole derivatization reagent.
database_cross_reference: PSI:XL

halomethylsilyl reagent
type: Class
subclass of: silylation reagent
definition: Halogenation reagent which can produce both silylated and halogenated derivatives.
has_obo_namespace: XLMOD
id: XLMOD:06008

Axiom
annotated source: halomethylsilyl reagent
annotated property: definition
annotated target: Halogenation reagent which can produce both silylated and halogenated derivatives.
database_cross_reference: PSI:XL

chiral derivatization reagent
type: Class
subclass of: GCMS derivatization reagent
definition: Chiral derivatization reagent with an enatiomerically pure chiral derivatizing agent to form two diastereomeric derivatives that can be separated by gas chromatography.
has_obo_namespace: XLMOD
id: XLMOD:06009

Axiom
annotated source: chiral derivatization reagent
annotated property: definition
annotated target: Chiral derivatization reagent with an enatiomerically pure chiral derivatizing agent to form two diastereomeric derivatives that can be separated by gas chromatography.
database_cross_reference: PSI:XL

LCMS derivatization reagent
type: Class
subclass of: derivatization entity
definition: Chemical reagent, which transforms an analyte so that its stability, separation, extraction, ionization efficiency and MS2 detectability are improved in LC-MS analysis.
has_obo_namespace: XLMOD
id: XLMOD:06010

Axiom
annotated source: LCMS derivatization reagent
annotated property: definition
annotated target: Chemical reagent, which transforms an analyte so that its stability, separation, extraction, ionization efficiency and MS2 detectability are improved in LC-MS analysis.
database_cross_reference: PSI:XL

dialkylacetal
type: Class
subclass of: alkylation reagent
definition: Dialkylacetal reagent.
has_obo_namespace: XLMOD
id: XLMOD:06011

Axiom
annotated source: dialkylacetal
annotated property: definition
annotated target: Dialkylacetal reagent.
database_cross_reference: PSI:XL

diazoalkal
type: Class
subclass of: alkylation reagent
definition: Diazoalkal reagent.
has_obo_namespace: XLMOD
id: XLMOD:06012

Axiom
annotated source: diazoalkal
annotated property: definition
annotated target: Diazoalkal reagent.
database_cross_reference: PSI:XL

TMS reagent
type: Class
subclass of: silylation reagent
definition: Trimethylsilyl (TMS) reagent replacing an active hydrogen by a silyl group.
has_obo_namespace: XLMOD
id: XLMOD:06013

Axiom
annotated source: TMS reagent
annotated property: definition
annotated target: Trimethylsilyl (TMS) reagent replacing an active hydrogen by a silyl group.
database_cross_reference: PSI:XL

DMS reagent
type: Class
subclass of: silylation reagent
definition: Dimethylsilyl (DMS) reagent replacing an active hydrogen by a silyl group.
has_obo_namespace: XLMOD
id: XLMOD:06014

Axiom
annotated source: DMS reagent
annotated property: definition
annotated target: Dimethylsilyl (DMS) reagent replacing an active hydrogen by a silyl group.
database_cross_reference: PSI:XL

TFA reagent
type: Class
subclass of: acylation reagent
definition: Trifluoroacetyl (TFA) reagent replacing an active hydrogen by a silyl group.
has_obo_namespace: XLMOD
id: XLMOD:06015

Axiom
annotated source: TFA reagent
annotated property: definition
annotated target: Trifluoroacetyl (TFA) reagent replacing an active hydrogen by a silyl group.
database_cross_reference: PSI:XL

boron trifluoride reagent
type: Class
subclass of: alkylation reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Boron trifluoride reagent.
has_obo_namespace: XLMOD
id: XLMOD:06016

Axiom
annotated source: boron trifluoride reagent
annotated property: definition
annotated target: Boron trifluoride reagent.
database_cross_reference: PSI:XL

N,N-Dimethylformamidedialkyl acetal
type: Class
subclass of: alkylation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: N,N-Dimethylformamidedialkyl acetal.
has_obo_namespace: XLMOD
id: XLMOD:06017

Axiom
annotated source: N,N-Dimethylformamidedialkyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidedialkyl acetal.
database_cross_reference: PSI:XL

chloroformate reagent
type: Class
subclass of: alkylation reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: chloroformate reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: Chloroformate reagent.
has_obo_namespace: XLMOD
id: XLMOD:06018

Axiom
annotated source: chloroformate reagent
annotated property: definition
annotated target: Chloroformate reagent.
database_cross_reference: PSI:XL

trialkyloxonium reagent
type: Class
subclass of: alkylation reagent
definition: Trialkyloxonium reagent.
has_obo_namespace: XLMOD
id: XLMOD:06019

Axiom
annotated source: trialkyloxonium reagent
annotated property: definition
annotated target: Trialkyloxonium reagent.
database_cross_reference: PSI:XL

arylation reagent
type: Class
subclass of: alkylation reagent
definition: Derivatization reagent replacing an active hydrogen by an aliphatic-aromatic group, e.g. a -phenyl, -tolyl, -xylyl, -naphthy, -benzyl group.
has_obo_namespace: XLMOD
id: XLMOD:06020

Axiom
annotated source: arylation reagent
annotated property: definition
annotated target: Derivatization reagent replacing an active hydrogen by an aliphatic-aromatic group, e.g. a -phenyl, -tolyl, -xylyl, -naphthy, -benzyl group.
database_cross_reference: PSI:XL

chromophore
type: Class
subclass of: derivatization entity
definition: A chromophore group attached to a derivatization reagent for enhanced UB- or VIS-detectability.
has_obo_namespace: XLMOD
id: XLMOD:06100

Axiom
annotated source: chromophore
annotated property: definition
annotated target: A chromophore group attached to a derivatization reagent for enhanced UB- or VIS-detectability.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

fluorophore
type: Class
subclass of: derivatization entity
definition: A fluorophore group attached to a derivatization reagent for enhanced fluorescence or chemiluminescence detectability.
has_obo_namespace: XLMOD
id: XLMOD:06101

Axiom
annotated source: fluorophore
annotated property: definition
annotated target: A fluorophore group attached to a derivatization reagent for enhanced fluorescence or chemiluminescence detectability.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

electrophore
type: Class
subclass of: derivatization entity
definition: An electrophore group attached to a derivatization reagent for enhanced electrochemical detectability.
has_obo_namespace: XLMOD
id: XLMOD:06102

Axiom
annotated source: electrophore
annotated property: definition
annotated target: An electrophore group attached to a derivatization reagent for enhanced electrochemical detectability.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

4-nitrophenyl
type: Class
subclass of: fluorophore
definition: 4-Nitrophenyl fluorophore.
max absorption: 265 nm
has_obo_namespace: XLMOD
id: XLMOD:06103

Axiom
annotated source: 4-nitrophenyl
annotated property: definition
annotated target: 4-Nitrophenyl fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

2,4-dinitrophenyl
type: Class
subclass of: fluorophore
definition: 2,4-Dinitrophenyl fluorophore.
has_obo_namespace: XLMOD
id: XLMOD:06104

Axiom
annotated source: 2,4-dinitrophenyl
annotated property: definition
annotated target: 2,4-Dinitrophenyl fluorophore.
database_cross_reference: PSI:XL

3,5-dinitrobenzyl
type: Class
subclass of: fluorophore
definition: 3,5-Dinitrobenzyl fluorophore.
has_obo_namespace: XLMOD
id: XLMOD:06105

Axiom
annotated source: 3,5-dinitrobenzyl
annotated property: definition
annotated target: 3,5-Dinitrobenzyl fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

4-chlorobenzoate
type: Class
subclass of: fluorophore
definition: 4-Chlorobenzoatel fluorophore.
max absorption: 236 nm
has_obo_namespace: XLMOD
id: XLMOD:06106

Axiom
annotated source: 4-chlorobenzoate
annotated property: definition
annotated target: 4-Chlorobenzoatel fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

4-nitrobenzoate
type: Class
subclass of: fluorophore
definition: 4-Nitrobenzoatel fluorophore.
max absorption: 254 nm
has_obo_namespace: XLMOD
id: XLMOD:06107

Axiom
annotated source: 4-nitrobenzoate
annotated property: definition
annotated target: 4-Nitrobenzoatel fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

toluoyl
type: Class
subclass of: fluorophore
definition: Toluoyll fluorophore.
max absorption: 236 nm
has_obo_namespace: XLMOD
id: XLMOD:06108

Axiom
annotated source: toluoyl
annotated property: definition
annotated target: Toluoyll fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

anisyl
type: Class
subclass of: fluorophore
definition: Anisyl fluorophore.
max absorption: 262 nm
has_obo_namespace: XLMOD
id: XLMOD:06109

Axiom
annotated source: anisyl
annotated property: definition
annotated target: Anisyl fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

phenacyl
type: Class
subclass of: fluorophore
definition: Phenacyl fluorophore.
max absorption: 250 nm
has_obo_namespace: XLMOD
id: XLMOD:06110

Axiom
annotated source: phenacyl
annotated property: definition
annotated target: Phenacyl fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

4-bromophenacyl
type: Class
subclass of: fluorophore
definition: 4-Bromophenacyl fluorophore.
max absorption: 260 nm
has_obo_namespace: XLMOD
id: XLMOD:06111

Axiom
annotated source: 4-bromophenacyl
annotated property: definition
annotated target: 4-Bromophenacyl fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

2-naphthacyl
type: Class
subclass of: fluorophore
definition: 2-Naphthacyl fluorophore.
max absorption: 248 nm
has_obo_namespace: XLMOD
id: XLMOD:06112

Axiom
annotated source: 2-naphthacyl
annotated property: definition
annotated target: 2-Naphthacyl fluorophore.
database_cross_reference: DOI:10.1016/B978-0-12-415806-1.00002-4

secondary amine reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a reactive group is reactive with secondary amino (=NH) groups.
has_obo_namespace: XLMOD
id: XLMOD:06500

Axiom
annotated source: secondary amine reactive
annotated property: definition
annotated target: Indicates that a reactive group is reactive with secondary amino (=NH) groups.
database_cross_reference: PSI:XL

active hydrogen reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with active hydrogens like e.g. from -SH, -OH, -NH, -COOH groups.
has_obo_namespace: XLMOD
id: XLMOD:06501

Axiom
annotated source: active hydrogen reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with active hydrogens like e.g. from -SH, -OH, -NH, -COOH groups.
database_cross_reference: PSI:XL

amide reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with amides.
has_obo_namespace: XLMOD
id: XLMOD:06502

Axiom
annotated source: amide reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with amides.
database_cross_reference: PSI:XL

amino acid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with amino acids.
has_obo_namespace: XLMOD
id: XLMOD:06503

Axiom
annotated source: amino acid reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with amino acids.
database_cross_reference: PSI:XL

nitrosamine reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with nitrosamines.
has_obo_namespace: XLMOD
id: XLMOD:06504

Axiom
annotated source: nitrosamine reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with nitrosamines.
database_cross_reference: PSI:XL

sulfonamide reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with sulfonamides.
has_obo_namespace: XLMOD
id: XLMOD:06505

Axiom
annotated source: sulfonamide reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with sulfonamides.
database_cross_reference: PSI:XL

carbohydrate reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with carbohydrates and sugars.
has_obo_namespace: XLMOD
id: XLMOD:06506

Axiom
annotated source: carbohydrate reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with carbohydrates and sugars.
database_cross_reference: PSI:XL

catecholamine reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with catecholamines.
has_obo_namespace: XLMOD
id: XLMOD:06507

Axiom
annotated source: catecholamine reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with catecholamines.
database_cross_reference: PSI:XL

sulfide reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with sulfides.
has_obo_namespace: XLMOD
id: XLMOD:06508

Axiom
annotated source: sulfide reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with sulfides.
database_cross_reference: PSI:XL

phenol reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with phenols.
has_obo_namespace: XLMOD
id: XLMOD:06509

Axiom
annotated source: phenol reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with phenols.
database_cross_reference: PSI:XL

ketone reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with ketones.
has_obo_namespace: XLMOD
id: XLMOD:06510

Axiom
annotated source: ketone reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with ketones.
database_cross_reference: PSI:XL

biphosphonate drug reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with biphosphonate drugs.
has_obo_namespace: XLMOD
id: XLMOD:06511

Axiom
annotated source: biphosphonate drug reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with biphosphonate drugs.
database_cross_reference: PSI:XL

steroid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with steroids.
has_obo_namespace: XLMOD
id: XLMOD:06512

Axiom
annotated source: steroid reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with steroids.
database_cross_reference: PSI:XL

thiol reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with thiols.
has_obo_namespace: XLMOD
id: XLMOD:06513

Axiom
annotated source: thiol reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with thiols.
database_cross_reference: PSI:XL

Vitamin D metabolite reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with vitamin D metabolites.
has_obo_namespace: XLMOD
id: XLMOD:06514

Axiom
annotated source: Vitamin D metabolite reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with vitamin D metabolites.
database_cross_reference: PSI:XL

nucleoside reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with nucleosides.
has_obo_namespace: XLMOD
id: XLMOD:06515

Axiom
annotated source: nucleoside reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with nucleosides.
database_cross_reference: PSI:XL

cholesterol reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with cholesterols.
has_obo_namespace: XLMOD
id: XLMOD:06516

Axiom
annotated source: cholesterol reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with cholesterols.
database_cross_reference: PSI:XL

histamine reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with histamines.
has_obo_namespace: XLMOD
id: XLMOD:06517

Axiom
annotated source: histamine reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with histamines.
database_cross_reference: PSI:XL

glycan reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with glycans.
has_obo_namespace: XLMOD
id: XLMOD:06518

Axiom
annotated source: glycan reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with glycans.
database_cross_reference: PSI:XL

alpha-keto acid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with alpha-keto-acids.
has_obo_namespace: XLMOD
id: XLMOD:06519

Axiom
annotated source: alpha-keto acid reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with alpha-keto-acids.
database_cross_reference: PSI:XL

citric acid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with citric acid.
has_obo_namespace: XLMOD
id: XLMOD:06520

Axiom
annotated source: citric acid reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with citric acid.
database_cross_reference: PSI:XL

phophate reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with phosphate.
has_obo_namespace: XLMOD
id: XLMOD:06521

Axiom
annotated source: phophate reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with phosphate.
database_cross_reference: PSI:XL

perfluorinated carboxylic acid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with perfluorinated carboxylic acids.
has_obo_namespace: XLMOD
id: XLMOD:06522

Axiom
annotated source: perfluorinated carboxylic acid reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with perfluorinated carboxylic acids.
database_cross_reference: PSI:XL

sialic acid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with sialic acid.
has_obo_namespace: XLMOD
id: XLMOD:06523

Axiom
annotated source: sialic acid reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with sialic acid.
database_cross_reference: PSI:XL

bile acid reactive
type: Class
subclass of: chemically reactive
definition: Indicates that a derivatization reagent is reactive with bile acids.
has_obo_namespace: XLMOD
id: XLMOD:06524

Axiom
annotated source: bile acid reactive
annotated property: definition
annotated target: Indicates that a derivatization reagent is reactive with bile acids.
database_cross_reference: PSI:XL

dimethylformamide
type: Class
subclass of: dialkylacetal
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amide reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: nitrosamine reactive
definition: Dimethylformamide.
has_exact_synonym: DMF
has_obo_namespace: XLMOD
id: XLMOD:07000

Axiom
annotated source: dimethylformamide
annotated property: definition
annotated target: Dimethylformamide.
database_cross_reference: CAS:68-12-2
database_cross_reference: ChemSpiderID:5993
database_cross_reference: ChemicalBookNo:CB2854115
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00003284
database_cross_reference: PubChem_Compound:6228

diazomethane
type: Class
subclass of: LCMS derivatization reagent
subclass of: diazoalkal
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: biphosphonate drug reactive
definition: Diazomethane.
has_obo_namespace: XLMOD
id: XLMOD:07001

Axiom
annotated source: diazomethane
annotated property: definition
annotated target: Diazomethane.
database_cross_reference: CAS:334-88-3
database_cross_reference: ChemSpiderID:9176
database_cross_reference: ChemicalBookNo:CB4852342
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:9550

pentafluorobenzyl bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: arylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzyl bromide reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: nitrosamine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfonamide reactive
definition: Pentafluorobenzyl bromide.
has_exact_synonym: PFBBr
has_obo_namespace: XLMOD
id: XLMOD:07002

Axiom
annotated source: pentafluorobenzyl bromide
annotated property: definition
annotated target: Pentafluorobenzyl bromide.
database_cross_reference: CAS:1765-40-8
database_cross_reference: ChemSpiderID:67069
database_cross_reference: ChemicalBookNo:CB9238273
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00000299
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:74484

pentafluorobenzylhydroxylaminehydrochloride
type: Class
subclass of: arylation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbonyl reactive
definition: Pentafluorobenzylhydroxylaminehydrochloride.
has_exact_synonym: PFBHA
has_obo_namespace: XLMOD
id: XLMOD:07003

Axiom
annotated source: pentafluorobenzylhydroxylaminehydrochloride
annotated property: definition
annotated target: Pentafluorobenzylhydroxylaminehydrochloride.
database_cross_reference: Beilstein:4031190
database_cross_reference: CAS:57981-02-9
database_cross_reference: ChemicalBookNo:CB8307815
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00012953
database_cross_reference: PubChem_Compound:129670358

benzylbromide
type: Class
subclass of: arylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzyl bromide reactive group
definition: Benzylbromide.
has_exact_synonym: BnBr
has_obo_namespace: XLMOD
id: XLMOD:07004

Axiom
annotated source: benzylbromide
annotated property: definition
annotated target: Benzylbromide.
database_cross_reference: CAS:100-39-0
database_cross_reference: ChemSpiderID:13851576
database_cross_reference: ChemicalBookNo:CB6761035
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:7498

tetrabutylammoniumhydroxide
type: Class
subclass of: alkylation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Tetrabutylammoniumhydroxide.
has_exact_synonym: TBH
has_obo_namespace: XLMOD
id: XLMOD:07005

Axiom
annotated source: tetrabutylammoniumhydroxide
annotated property: definition
annotated target: Tetrabutylammoniumhydroxide.
database_cross_reference: CAS:2052-49-5
database_cross_reference: ChemSpiderID:13851576
database_cross_reference: ChemicalBookNo:CB6371870
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00009425
database_cross_reference: PubChem_Compound:2723671

boron trifluoride
type: Class
subclass of: boron trifluoride reagent
definition: Boron trifluoride derivatization reagent.
has_exact_synonym: BF3
has_obo_namespace: XLMOD
id: XLMOD:07006

Axiom
annotated source: boron trifluoride
annotated property: definition
annotated target: Boron trifluoride derivatization reagent.
database_cross_reference: CAS:7637-07-2
database_cross_reference: ChemSpiderID:6116
database_cross_reference: ChemicalBookNo:CB3238105
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00011316

bis(trimethylsilyl)acetamide
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amide reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Bis(trimethylsilyl)acetamide.
has_exact_synonym: BSA
has_exact_synonym: N,O-Bis(trimethylsilyl)acetamide
has_obo_namespace: XLMOD
id: XLMOD:07007

Axiom
annotated source: bis(trimethylsilyl)acetamide
annotated property: definition
annotated target: Bis(trimethylsilyl)acetamide.
database_cross_reference: Beilstein:1306669
database_cross_reference: CAS:10416-59-8
database_cross_reference: ChemSpiderID:4523073
database_cross_reference: ChemicalBookNo:CB7366985
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00008270
database_cross_reference: PubChem_Compound:6913588

bis(trimethylsilyl)trifluoroacetamide
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: nitrosamine reactive
definition: Bis(trimethylsilyl)trifluoroacetamide.
has_exact_synonym: BSTFA
has_obo_namespace: XLMOD
id: XLMOD:07008

Axiom
annotated source: bis(trimethylsilyl)trifluoroacetamide
annotated property: definition
annotated target: Bis(trimethylsilyl)trifluoroacetamide.
database_cross_reference: CAS:25561-30-2
database_cross_reference: ChemSpiderID:58770
database_cross_reference: ChemicalBookNo:CB5464744
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:94358

N-methyl-trimethylsilyltrifluoroacetamide
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: N-methyl-trimethylsilyltrifluoroacetamide.
has_exact_synonym: MSTFA
has_obo_namespace: XLMOD
id: XLMOD:07009

Axiom
annotated source: N-methyl-trimethylsilyltrifluoroacetamide
annotated property: definition
annotated target: N-methyl-trimethylsilyltrifluoroacetamide.
database_cross_reference: Beilstein:1941550
database_cross_reference: CAS:24589-78-4
database_cross_reference: ChemSpiderID:30134
database_cross_reference: ChemicalBookNo:CB0161574
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00000411
database_cross_reference: PMID:26478271
database_cross_reference: PubChem_Compound:32510

hexamethyldisilazane
type: Class
subclass of: silylation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbohydrate reactive
definition: Hexamethyldisilazane.
has_exact_synonym: HMDS
has_obo_namespace: XLMOD
id: XLMOD:07010

Axiom
annotated source: hexamethyldisilazane
annotated property: definition
annotated target: Hexamethyldisilazane.
database_cross_reference: CAS:999-97-3
database_cross_reference: ChemSpiderID:13238
database_cross_reference: ChemicalBookNo:CB9105784
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:13838

trimethylchlorosilane
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbohydrate reactive
definition: Trimethylchlorosilane.
has_exact_synonym: CMTS
has_exact_synonym: Chlorotrimethylsilane
has_exact_synonym: TMCS
has_obo_namespace: XLMOD
id: XLMOD:07011

Axiom
annotated source: trimethylchlorosilane
annotated property: definition
annotated target: Trimethylchlorosilane.
database_cross_reference: Beilstein:1209232
database_cross_reference: CAS:75-77-4
database_cross_reference: ChemSpiderID:6157
database_cross_reference: ChemicalBookNo:CB4375627
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00000502
database_cross_reference: PMID:19525080
database_cross_reference: PubChem_Compound:6397

trimethylsilylimidazole
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbohydrate reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: catecholamine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfide reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Trimethylsilylimidazole.
has_exact_synonym: 1-(Trimethylsilyl)imidazole
has_exact_synonym: TMSI
has_exact_synonym: TMSIM
has_obo_namespace: XLMOD
id: XLMOD:07012

Axiom
annotated source: trimethylsilylimidazole
annotated property: definition
annotated target: Trimethylsilylimidazole.
database_cross_reference: Beilstein:606148
database_cross_reference: CAS:18156-74-6
database_cross_reference: ChemSpiderID:26905
database_cross_reference: ChemicalBookNo:CB5483743
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00005280
database_cross_reference: PMID:26478271
database_cross_reference: PubChem_Compound:28925

trimethylsilyldiethylamine
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Trimethylsilyldiethylamine.
has_exact_synonym: TMS-DEA
has_obo_namespace: XLMOD
id: XLMOD:07013

Axiom
annotated source: trimethylsilyldiethylamine
annotated property: definition
annotated target: Trimethylsilyldiethylamine.
database_cross_reference: CAS:996-50-9
database_cross_reference: ChemSpiderID:63633
database_cross_reference: ChemicalBookNo:CB3771284
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:70454

N-methyl-N-t-butyldimethylsilyltrifluoroacetamide
type: Class
subclass of: DMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: N-methyl-N-t-butyldimethylsilyltrifluoroacetamide.
has_exact_synonym: 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane
has_exact_synonym: MTBSTFA
has_obo_namespace: XLMOD
id: XLMOD:07014

Axiom
annotated source: N-methyl-N-t-butyldimethylsilyltrifluoroacetamide
annotated property: definition
annotated target: N-methyl-N-t-butyldimethylsilyltrifluoroacetamide.
database_cross_reference: Beilstein:3606546
database_cross_reference: CAS:77377-52-7
database_cross_reference: ChemSpiderID:2006425
database_cross_reference: ChemicalBookNo:CB7707814
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00009671
database_cross_reference: PMID:26478271
database_cross_reference: PubChem_Compound:2724275

trifluoroacetoic anhydride
type: Class
subclass of: fluorinated anhydride reagent
subclass of: TFA reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
definition: Trifluoroacetoic anhydride.
has_exact_synonym: TFAA
has_obo_namespace: XLMOD
id: XLMOD:07015

Axiom
annotated source: trifluoroacetoic anhydride
annotated property: definition
annotated target: Trifluoroacetoic anhydride.
database_cross_reference: CAS:407-25-0
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:9845

pentafluoropropionic anhydride
type: Class
subclass of: fluorinated anhydride reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: nitrosamine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: catecholamine reactive
definition: Pentafluoropropionic anhydride.
has_exact_synonym: PFPA
has_obo_namespace: XLMOD
id: XLMOD:07016

Axiom
annotated source: pentafluoropropionic anhydride
annotated property: definition
annotated target: Pentafluoropropionic anhydride.
database_cross_reference: Beilstein:1806446
database_cross_reference: CAS:356-42-3
database_cross_reference: ChemicalBookNo:CB2749284
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00000429
database_cross_reference: PubChem_Compound:67742

heptafluorobutyric anhydride
type: Class
subclass of: fluorinated anhydride reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: nitrosamine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfonamide reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Heptafluorobutyric anhydride.
has_exact_synonym: HFBA
has_obo_namespace: XLMOD
id: XLMOD:07017

Axiom
annotated source: heptafluorobutyric anhydride
annotated property: definition
annotated target: Heptafluorobutyric anhydride.
database_cross_reference: Beilstein:856036
database_cross_reference: CAS:336-59-4
database_cross_reference: ChemSpiderID:60962
database_cross_reference: ChemicalBookNo:CB5217287
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00000432
database_cross_reference: PMID:26478271
database_cross_reference: PubChem_Compound:67643

trifluoroacetylimidazole
type: Class
subclass of: fluorinated anhydride reagent
subclass of: TFA reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
definition: Trifluoroacetylimidazole.
has_exact_synonym: TFAI
has_obo_namespace: XLMOD
id: XLMOD:07018

Axiom
annotated source: trifluoroacetylimidazole
annotated property: definition
annotated target: Trifluoroacetylimidazole.
database_cross_reference: Beilstein:608904
database_cross_reference: CAS:1546-79-8
database_cross_reference: ChemSpiderID:66407
database_cross_reference: ChemicalBookNo:CB7308204
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00014501
database_cross_reference: PubChem_Compound:73767

pentafluoropropanylimidazole
type: Class
subclass of: fluorinated anhydride reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
definition: Pentafluoropropanylimidazole.
has_exact_synonym: PFPI
has_obo_namespace: XLMOD
id: XLMOD:07019

Axiom
annotated source: pentafluoropropanylimidazole
annotated property: definition
annotated target: Pentafluoropropanylimidazole.
database_cross_reference: DOI:10.5772/33098

heptafluorobutyrylimidazole
type: Class
subclass of: fluorinated anhydride reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amide reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: catecholamine reactive
definition: Heptafluorobutyrylimidazole.
has_exact_synonym: HFBI
has_obo_namespace: XLMOD
id: XLMOD:07020

Axiom
annotated source: heptafluorobutyrylimidazole
annotated property: definition
annotated target: Heptafluorobutyrylimidazole.
database_cross_reference: CAS:32477-35-3
database_cross_reference: ChemSpiderID:85218
database_cross_reference: ChemicalBookNo:CB4100522
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00014503
database_cross_reference: PubChem_Compound:94431

N-Methyl-bis(trifluoroacetamide)
type: Class
subclass of: TFA reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
definition: N-Methyl-bis(trifluoroacetamide).
has_exact_synonym: MBTFA
has_obo_namespace: XLMOD
id: XLMOD:07021

Axiom
annotated source: N-Methyl-bis(trifluoroacetamide)
annotated property: definition
annotated target: N-Methyl-bis(trifluoroacetamide).
database_cross_reference: Beilstein:1878402
database_cross_reference: CAS:685-27-8
database_cross_reference: ChemSpiderID:62836
database_cross_reference: ChemicalBookNo:CB0220312
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00000412
database_cross_reference: PubChem_Compound:69635

pentafluorobenzoyl chloride
type: Class
subclass of: silylation reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: acyl chloride
definition: Pentafluorobenzoyl chloride.
has_exact_synonym: PFBC
has_obo_namespace: XLMOD
id: XLMOD:07022

Axiom
annotated source: pentafluorobenzoyl chloride
annotated property: definition
annotated target: Pentafluorobenzoyl chloride.
database_cross_reference: Beilstein:2054397
database_cross_reference: CAS:2251-50-5
database_cross_reference: ChemSpiderID:67799
database_cross_reference: ChemicalBookNo:CB6191348
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00000657
database_cross_reference: PubChem_Compound:75256

pentafluoropropanol
type: Class
subclass of: silylation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
definition: Pentafluoropropanol.
has_exact_synonym: PFPOH
has_obo_namespace: XLMOD
id: XLMOD:07023

Axiom
annotated source: pentafluoropropanol
annotated property: definition
annotated target: Pentafluoropropanol.
database_cross_reference: CAS:679-86-7
database_cross_reference: ChemSpiderID:9488
database_cross_reference: ChemicalBookNo:CB9689963
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00153226
database_cross_reference: PubChem_Compound:168785

4-Carbethoxyhexafluorobutyrylchloride
type: Class
subclass of: silylation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 4-Carbethoxyhexafluorobutyrylchloride.
has_exact_synonym: 4-CB
has_obo_namespace: XLMOD
id: XLMOD:07024

Axiom
annotated source: 4-Carbethoxyhexafluorobutyrylchloride
annotated property: definition
annotated target: 4-Carbethoxyhexafluorobutyrylchloride.
database_cross_reference: CAS:18381-53-8
database_cross_reference: ChemSpiderID:141651
database_cross_reference: ChemicalBookNo:CB2153034
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:161251

N-trifluoroacetyl-L-prolylchloride
type: Class
subclass of: chiral derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: N-trifluoroacetyl-L-prolylchloride.
has_exact_synonym: TPC
has_obo_namespace: XLMOD
id: XLMOD:07025

Axiom
annotated source: N-trifluoroacetyl-L-prolylchloride
annotated property: definition
annotated target: N-trifluoroacetyl-L-prolylchloride.
database_cross_reference: CAS:36724-68-2
database_cross_reference: ChemicalBookNo:CB1411487
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:3082449

(S)-(-)-N-(Trifluoroacetyl)-prolylchloride
type: Class
subclass of: chiral derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: (S)-(-)-N-(Trifluoroacetyl)-prolylchloride.
has_exact_synonym: I-TPC
has_obo_namespace: XLMOD
id: XLMOD:07026

Axiom
annotated source: (S)-(-)-N-(Trifluoroacetyl)-prolylchloride
annotated property: definition
annotated target: (S)-(-)-N-(Trifluoroacetyl)-prolylchloride.
database_cross_reference: CAS:36724-68-2
database_cross_reference: ChemicalBookNo:3082449
database_cross_reference: DOI:10.5772/33098
database_cross_reference: PubChem_Compound:3082449

(-)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
type: Class
subclass of: chiral derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: (-)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid.
has_exact_synonym: MTPA
has_obo_namespace: XLMOD
id: XLMOD:07027

Axiom
annotated source: (-)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
annotated property: definition
annotated target: (-)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid.
database_cross_reference: CAS:56135-03-6
database_cross_reference: DOI:10.5772/33098
database_cross_reference: MDL:MFCD00066637
database_cross_reference: PubChem_Compound:2723917

oximation reagent
type: Class
subclass of: GCMS derivatization reagent
definition: Oximation reagent replacing an aldehyde keto group with an O-methyloxime group.
has_obo_namespace: XLMOD
id: XLMOD:07028

Axiom
annotated source: oximation reagent
annotated property: definition
annotated target: Oximation reagent replacing an aldehyde keto group with an O-methyloxime group.
database_cross_reference: PSI:XL

methoxylamine hydrochloride
type: Class
subclass of: alkylation reagent
subclass of: oximation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbohydrate reactive
definition: Methoxylamine hydrochloride.
has_exact_synonym: Methoxyammonium chloride
has_exact_synonym: O-Methylhydroxylamine hydrochloride
has_obo_namespace: XLMOD
id: XLMOD:07029

Axiom
annotated source: methoxylamine hydrochloride
annotated property: definition
annotated target: Methoxylamine hydrochloride.
database_cross_reference: Beilstein:3589723
database_cross_reference: CAS:593-56-6
database_cross_reference: ChemSpiderID:455236
database_cross_reference: ChemicalBookNo:CB3439014
database_cross_reference: MDL:MFCD00012951
database_cross_reference: PubChem_Compound:521874

Trimethyliodosilane
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Trimethyliodosilane.
has_exact_synonym: TMIS
has_obo_namespace: XLMOD
id: XLMOD:07030

Axiom
annotated source: Trimethyliodosilane
annotated property: definition
annotated target: Trimethyliodosilane.
database_cross_reference: PMID:26478271

deuterium labelled N-methyl-trimethylsilyltrifluoroacetamide
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Deuterium labelled N-methyl-trimethylsilyltrifluoroacetamide.
has_exact_synonym: MSTFA-d9
has_obo_namespace: XLMOD
id: XLMOD:07031

Axiom
annotated source: deuterium labelled N-methyl-trimethylsilyltrifluoroacetamide
annotated property: definition
annotated target: Deuterium labelled N-methyl-trimethylsilyltrifluoroacetamide.
database_cross_reference: CAS:945623-67-6
database_cross_reference: ChemicalBookNo:CB72545465
database_cross_reference: PMID:23628173

deuterium labelled N-methyl-N-t-butyldimethylsilyltrifluoroacetamide
type: Class
subclass of: DMS reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: active hydrogen reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Deuterium labelled N-methyl-N-t-butyldimethylsilyltrifluoroacetamide.
has_exact_synonym: MTBSTFA-d6
has_obo_namespace: XLMOD
id: XLMOD:07032

Axiom
annotated source: deuterium labelled N-methyl-N-t-butyldimethylsilyltrifluoroacetamide
annotated property: definition
annotated target: Deuterium labelled N-methyl-N-t-butyldimethylsilyltrifluoroacetamide.
database_cross_reference: PMID:23628173

deuterium labelled methyl chloroformate
type: Class
subclass of: chloroformate reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled methyl chloroformate.
has_exact_synonym: MCF-d3
has_obo_namespace: XLMOD
id: XLMOD:07033

Axiom
annotated source: deuterium labelled methyl chloroformate
annotated property: definition
annotated target: Deuterium labelled methyl chloroformate.
database_cross_reference: PMID:23628173

methyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: Methyl chloroformate.
has_exact_synonym: MCF
has_obo_namespace: XLMOD
id: XLMOD:07034

Axiom
annotated source: methyl chloroformate
annotated property: definition
annotated target: Methyl chloroformate.
database_cross_reference: CAS:79-22-1
database_cross_reference: ChemSpiderID:6337
database_cross_reference: PubChem_Compound:6586

9-Fluorenylmethyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: 9-Fluorenylmethyl chloroformate.
has_obo_namespace: XLMOD
id: XLMOD:07035

Axiom
annotated source: 9-Fluorenylmethyl chloroformate
annotated property: definition
annotated target: 9-Fluorenylmethyl chloroformate.
database_cross_reference: CAS:28920-43-6
database_cross_reference: ChemSpiderID:31647
database_cross_reference: ChemicalBookNo:CB7234569

trichloroethyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: Trichloroethyl chloroformate.
has_exact_synonym: TCECF
has_obo_namespace: XLMOD
id: XLMOD:07036

Axiom
annotated source: trichloroethyl chloroformate
annotated property: definition
annotated target: Trichloroethyl chloroformate.
database_cross_reference: CAS:17341-93-4
database_cross_reference: ChemSpiderID:78534
database_cross_reference: ChemicalBookNo:CB1372973
database_cross_reference: PubChem_Compound:87063

pentafluorobenzyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: Pentafluorobenzyl chloroformate.
has_exact_synonym: PFBCF
has_obo_namespace: XLMOD
id: XLMOD:07037

Axiom
annotated source: pentafluorobenzyl chloroformate
annotated property: definition
annotated target: Pentafluorobenzyl chloroformate.
database_cross_reference: CAS:53526-74-2
database_cross_reference: ChemSpiderID:2056259
database_cross_reference: ChemicalBookNo:CB8165220
database_cross_reference: PubChem_Compound:2775932

1-chloroethyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: 1-chloroethyl chloroformate.
has_exact_synonym: 1CEF
has_obo_namespace: XLMOD
id: XLMOD:07038

Axiom
annotated source: 1-chloroethyl chloroformate
annotated property: definition
annotated target: 1-chloroethyl chloroformate.
database_cross_reference: CAS:50893-53-3
database_cross_reference: ChemSpiderID:454726
database_cross_reference: ChemicalBookNo:CB5320341
database_cross_reference: PubChem_Compound:521305

N-Acetylimidazole
type: Class
subclass of: silylation reagent
definition: N-Acetylimidazole.
has_exact_synonym: AIM
has_obo_namespace: XLMOD
id: XLMOD:07039

Axiom
annotated source: N-Acetylimidazole
annotated property: definition
annotated target: N-Acetylimidazole.
database_cross_reference: CAS:2466-76-4
database_cross_reference: ChemSpiderID:16257
database_cross_reference: ChemicalBookNo:CB9339608
database_cross_reference: PubChem_Compound:17174

1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane
type: Class
subclass of: DMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane.
has_exact_synonym: CMTMS
has_obo_namespace: XLMOD
id: XLMOD:07040

Axiom
annotated source: 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane
annotated property: definition
annotated target: 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisilazane.
database_cross_reference: CAS:14579-91-0
database_cross_reference: ChemSpiderID:24914
database_cross_reference: ChemicalBookNo:CB1743876
database_cross_reference: PubChem_Compound:26740

Dimethylchlorosilane
type: Class
subclass of: DMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Dimethylchlorosilane.
has_exact_synonym: DMCS
has_obo_namespace: XLMOD
id: XLMOD:07041

Axiom
annotated source: Dimethylchlorosilane
annotated property: definition
annotated target: Dimethylchlorosilane.
database_cross_reference: CAS:1066-35-9
database_cross_reference: ChemSpiderID:59496
database_cross_reference: ChemicalBookNo:CB3694606
database_cross_reference: PubChem_Compound:6327132

N-Trimethylsilylacetamide
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbohydrate reactive
definition: N-Trimethylsilylacetamide.
has_exact_synonym: N-(Trimethylsilyl)acetamide
has_exact_synonym: TMSA
has_obo_namespace: XLMOD
id: XLMOD:07042

Axiom
annotated source: N-Trimethylsilylacetamide
annotated property: definition
annotated target: N-Trimethylsilylacetamide.
database_cross_reference: CAS:13435-12-6
database_cross_reference: ChemSpiderID:24208
database_cross_reference: ChemicalBookNo:CB7667530
database_cross_reference: PubChem_Compound:25989

N-(Trimethylsilyl)diethylamine
type: Class
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: N-(Trimethylsilyl)diethylamine.
has_exact_synonym: TMSDEA
has_obo_namespace: XLMOD
id: XLMOD:07043

Axiom
annotated source: N-(Trimethylsilyl)diethylamine
annotated property: definition
annotated target: N-(Trimethylsilyl)diethylamine.
database_cross_reference: CAS:996-50-9
database_cross_reference: ChemSpiderID:63633
database_cross_reference: ChemicalBookNo:CB3771284
database_cross_reference: PubChem_Compound:70454

trimethylphenylammonium hydroxide
type: Class
subclass of: alkylation reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amide reactive
definition: Trimethylphenylammonium hydroxide.
has_exact_synonym: MethElute reagent
has_exact_synonym: TMPAH
has_obo_namespace: XLMOD
id: XLMOD:07044

Axiom
annotated source: trimethylphenylammonium hydroxide
annotated property: definition
annotated target: Trimethylphenylammonium hydroxide.
database_cross_reference: CAS:1899-02-1
database_cross_reference: ChemSpiderID:15124
database_cross_reference: ChemicalBookNo:CB5316173
database_cross_reference: PubChem_Compound:15913

N,N-Dimethylformamidedimethyl acetal
type: Class
subclass of: N,N-Dimethylformamidedialkyl acetal
definition: N,N-Dimethylformamidedimethyl acetal.
has_exact_synonym: DMFDMA
has_exact_synonym: Methylate reagent
has_obo_namespace: XLMOD
id: XLMOD:07045

Axiom
annotated source: N,N-Dimethylformamidedimethyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidedimethyl acetal.
database_cross_reference: CAS:4637-24-5
database_cross_reference: ChemSpiderID:70742
database_cross_reference: ChemicalBookNo:CB8178244
database_cross_reference: PubChem_Compound:78373

dimethyldichlorosilane
type: Class
subclass of: DMS reagent
definition: Dimethyldichlorosilane.
has_exact_synonym: DMDCS
has_obo_namespace: XLMOD
id: XLMOD:07046

Axiom
annotated source: dimethyldichlorosilane
annotated property: definition
annotated target: Dimethyldichlorosilane.
database_cross_reference: CAS:75-78-5
database_cross_reference: ChemSpiderID:6158
database_cross_reference: ChemicalBookNo:CB8854243
database_cross_reference: PubChem_Compound:6398

N-t-Butyldimethylsilylimidazole
type: Class
subclass of: silylation reagent
definition: N-t-Butyldimethylsilylimidazole.
has_exact_synonym: TBDMSIM
has_obo_namespace: XLMOD
id: XLMOD:07047

Axiom
annotated source: N-t-Butyldimethylsilylimidazole
annotated property: definition
annotated target: N-t-Butyldimethylsilylimidazole.
database_cross_reference: CAS:54925-64-3
database_cross_reference: ChemSpiderID:149827
database_cross_reference: ChemicalBookNo:CB1271225
database_cross_reference: PubChem_Compound:171385

4-Trimethylsiloxy-3-penten-2-one
type: Class
subclass of: TMS reagent
definition: 4-Trimethylsiloxy-3-penten-2-one.
has_obo_namespace: XLMOD
id: XLMOD:07048

Axiom
annotated source: 4-Trimethylsiloxy-3-penten-2-one
annotated property: definition
annotated target: 4-Trimethylsiloxy-3-penten-2-one.
database_cross_reference: CAS:13257-81-3
database_cross_reference: ChemSpiderID:4518416
database_cross_reference: ChemicalBookNo:CB3457672
database_cross_reference: PubChem_Compound:6059369

bromotrimethylsilane
type: Class
subclass of: TMS reagent
definition: Bromotrimethylsilane.
has_obo_namespace: XLMOD
id: XLMOD:07049

Axiom
annotated source: bromotrimethylsilane
annotated property: definition
annotated target: Bromotrimethylsilane.
database_cross_reference: CAS:2857-97-8
database_cross_reference: ChemSpiderID:68599
database_cross_reference: ChemicalBookNo:CB9749809
database_cross_reference: PubChem_Compound:76113

triisopropylsilyl chloride
type: Class
subclass of: silylation reagent
definition: Triisopropylsilyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:07050

Axiom
annotated source: triisopropylsilyl chloride
annotated property: definition
annotated target: Triisopropylsilyl chloride.
database_cross_reference: CAS:13154-24-0
database_cross_reference: ChemSpiderID:122926
database_cross_reference: ChemicalBookNo:CB3405310
database_cross_reference: PubChem_Compound:139400

triisopropylsilyl trifluoromethanesulfonate
type: Class
subclass of: silylation reagent
definition: Triisopropylsilyl trifluoromethanesulfonate.
has_obo_namespace: XLMOD
id: XLMOD:07051

Axiom
annotated source: triisopropylsilyl trifluoromethanesulfonate
annotated property: definition
annotated target: Triisopropylsilyl trifluoromethanesulfonate.
database_cross_reference: CAS:80522-42-5
database_cross_reference: ChemSpiderID:2006662
database_cross_reference: ChemicalBookNo:CB5189874
database_cross_reference: PubChem_Compound:2724529

triethylsilyl trifluoromethanesulfonate
type: Class
subclass of: silylation reagent
definition: Triethylsilyl trifluoromethanesulfonate.
has_obo_namespace: XLMOD
id: XLMOD:07052

Axiom
annotated source: triethylsilyl trifluoromethanesulfonate
annotated property: definition
annotated target: Triethylsilyl trifluoromethanesulfonate.
database_cross_reference: CAS:79271-56-0
database_cross_reference: ChemSpiderID:2015110
database_cross_reference: ChemicalBookNo:CB6298346
database_cross_reference: PubChem_Compound:2733308

chlorotriethylsilane
type: Class
subclass of: silylation reagent
definition: Chlorotriethylsilane.
has_obo_namespace: XLMOD
id: XLMOD:07053

Axiom
annotated source: chlorotriethylsilane
annotated property: definition
annotated target: Chlorotriethylsilane.
database_cross_reference: CAS:994-30-9
database_cross_reference: ChemSpiderID:13221
database_cross_reference: ChemicalBookNo:CB4746520
database_cross_reference: PubChem_Compound:13819

chloro-dimethyl(pentafluorophenyl)silane
type: Class
subclass of: silylation reagent
definition: Chloro-dimethyl(pentafluorophenyl)silane.
has_obo_namespace: XLMOD
id: XLMOD:07054

Axiom
annotated source: chloro-dimethyl(pentafluorophenyl)silane
annotated property: definition
annotated target: Chloro-dimethyl(pentafluorophenyl)silane.
database_cross_reference: CAS:20082-71-7
database_cross_reference: ChemSpiderID:79715
database_cross_reference: ChemicalBookNo:CB8853291
database_cross_reference: PubChem_Compound:88361

N-Methyl-N-trimethylsilyl-heptafluorobutyramide
type: Class
subclass of: TMS reagent
definition: N-Methyl-N-trimethylsilyl-heptafluorobutyramide.
has_exact_synonym: Mshfba
has_obo_namespace: XLMOD
id: XLMOD:07055

Axiom
annotated source: N-Methyl-N-trimethylsilyl-heptafluorobutyramide
annotated property: definition
annotated target: N-Methyl-N-trimethylsilyl-heptafluorobutyramide.
database_cross_reference: CAS:53296-64-3
database_cross_reference: ChemSpiderID:2056039
database_cross_reference: ChemicalBookNo:CB1232811
database_cross_reference: PubChem_Compound:2775707

N-Methyl-N-trimethylsilylacetamide
type: Class
subclass of: TMS reagent
definition: N-Methyl-N-trimethylsilylacetamide.
has_obo_namespace: XLMOD
id: XLMOD:07056

Axiom
annotated source: N-Methyl-N-trimethylsilylacetamide
annotated property: definition
annotated target: N-Methyl-N-trimethylsilylacetamide.
database_cross_reference: CAS:7449-74-3
database_cross_reference: ChemSpiderID:73958
database_cross_reference: ChemicalBookNo:CB4355232
database_cross_reference: PubChem_Compound:81953

hexamethyldisiloxane
type: Class
subclass of: silylation reagent
definition: Hexamethyldisiloxane.
has_obo_namespace: XLMOD
id: XLMOD:07057

Axiom
annotated source: hexamethyldisiloxane
annotated property: definition
annotated target: Hexamethyldisiloxane.
database_cross_reference: CAS:107-46-0
database_cross_reference: ChemSpiderID:23150
database_cross_reference: ChemicalBookNo:CB2446352
database_cross_reference: PubChem_Compound:24764

1,1,3,3-Tetramethyl-1,3-diphenyldisilazane
type: Class
subclass of: silylation reagent
definition: 1,1,3,3-Tetramethyl-1,3-diphenyldisilazane.
has_obo_namespace: XLMOD
id: XLMOD:07058

Axiom
annotated source: 1,1,3,3-Tetramethyl-1,3-diphenyldisilazane
annotated property: definition
annotated target: 1,1,3,3-Tetramethyl-1,3-diphenyldisilazane.
database_cross_reference: CAS:3449-26-1
database_cross_reference: ChemSpiderID:69434
database_cross_reference: ChemicalBookNo:CB7212822
database_cross_reference: PubChem_Compound:76988

N,N-Dimethyltrimethylsilylamine
type: Class
subclass of: TMS reagent
definition: N,N-Dimethyltrimethylsilylamine.
has_obo_namespace: XLMOD
id: XLMOD:07059

Axiom
annotated source: N,N-Dimethyltrimethylsilylamine
annotated property: definition
annotated target: N,N-Dimethyltrimethylsilylamine.
database_cross_reference: CAS:2083-91-2
database_cross_reference: ChemSpiderID:67521
database_cross_reference: ChemicalBookNo:CB1279847
database_cross_reference: PubChem_Compound:74965

N,N'-Bis(trimethylsilyl)urea
type: Class
subclass of: TMS reagent
definition: N,N'-Bis(trimethylsilyl)urea.
has_obo_namespace: XLMOD
id: XLMOD:07060

Axiom
annotated source: N,N'-Bis(trimethylsilyl)urea
annotated property: definition
annotated target: N,N'-Bis(trimethylsilyl)urea.
database_cross_reference: CAS:18297-63-7
database_cross_reference: ChemSpiderID:78992
database_cross_reference: ChemicalBookNo:CB6152161
database_cross_reference: PubChem_Compound:87562

N,O-Bis(trimethylsilyl)carbamate
type: Class
subclass of: TMS reagent
definition: N,O-Bis(trimethylsilyl)carbamate.
has_obo_namespace: XLMOD
id: XLMOD:07061

Axiom
annotated source: N,O-Bis(trimethylsilyl)carbamate
annotated property: definition
annotated target: N,O-Bis(trimethylsilyl)carbamate.
database_cross_reference: CAS:35342-88-2
database_cross_reference: ChemSpiderID:2283833
database_cross_reference: ChemicalBookNo:CB2248969
database_cross_reference: PubChem_Compound:3015764

N,N-Bis(trimethylsilyl)methylamine
type: Class
subclass of: TMS reagent
definition: N,N-Bis(trimethylsilyl)methylamine.
has_obo_namespace: XLMOD
id: XLMOD:07062

Axiom
annotated source: N,N-Bis(trimethylsilyl)methylamine
annotated property: definition
annotated target: N,N-Bis(trimethylsilyl)methylamine.
database_cross_reference: CAS:920-68-3
database_cross_reference: ChemSpiderID:63385
database_cross_reference: ChemicalBookNo:CB0439806
database_cross_reference: PubChem_Compound:70199

bis(dimethylamino)dimethylsilane
type: Class
subclass of: silylation reagent
definition: Bis(dimethylamino)dimethylsilane.
has_obo_namespace: XLMOD
id: XLMOD:07063

Axiom
annotated source: bis(dimethylamino)dimethylsilane
annotated property: definition
annotated target: Bis(dimethylamino)dimethylsilane.
database_cross_reference: CAS:3768-58-9
database_cross_reference: ChemSpiderID:69798
database_cross_reference: ChemicalBookNo:CB1214899
database_cross_reference: PubChem_Compound:77384

Trimethylsilyl methallylsulfinate
type: Class
subclass of: TMS reagent
definition: Trimethylsilyl methallylsulfinate.
has_obo_namespace: XLMOD
id: XLMOD:07064

Axiom
annotated source: Trimethylsilyl methallylsulfinate
annotated property: definition
annotated target: Trimethylsilyl methallylsulfinate.
database_cross_reference: CAS:723336-86-5
database_cross_reference: ChemSpiderID:28419285
database_cross_reference: ChemicalBookNo:CB32750948
database_cross_reference: PubChem_Compound:71312539

Triethylsilyl methallylsulfinate
type: Class
subclass of: silylation reagent
definition: Triethylsilyl methallylsulfinate.
has_obo_namespace: XLMOD
id: XLMOD:07065

Axiom
annotated source: Triethylsilyl methallylsulfinate
annotated property: definition
annotated target: Triethylsilyl methallylsulfinate.
database_cross_reference: CAS:850418-19-8
database_cross_reference: ChemSpiderID:35789839
database_cross_reference: ChemicalBookNo:CB42756013
database_cross_reference: PubChem_Compound:71312540

tert-Butyldimethylsilyl methallylsulfinate
type: Class
subclass of: silylation reagent
definition: Tert-Butyldimethylsilyl methallylsulfinate.
has_exact_synonym: SILMAS-TBS
has_obo_namespace: XLMOD
id: XLMOD:07066

Axiom
annotated source: tert-Butyldimethylsilyl methallylsulfinate
annotated property: definition
annotated target: Tert-Butyldimethylsilyl methallylsulfinate.
database_cross_reference: CAS:850418-20-1
database_cross_reference: ChemSpiderID:35789840
database_cross_reference: ChemicalBookNo:CB72750946
database_cross_reference: PubChem_Compound:71312541

methyltrifluoromethanesulfonate
type: Class
subclass of: acylation reagent
definition: Methyltrifluoromethanesulfonate.
has_obo_namespace: XLMOD
id: XLMOD:07067

Axiom
annotated source: methyltrifluoromethanesulfonate
annotated property: definition
annotated target: Methyltrifluoromethanesulfonate.
database_cross_reference: CAS:333-27-7
database_cross_reference: ChemSpiderID:9153
database_cross_reference: ChemicalBookNo:CB9131563
database_cross_reference: PubChem_Compound:9526

ethyl trifluoromethanesulfonate
type: Class
subclass of: acylation reagent
definition: Ethyl trifluoromethanesulfonate.
has_obo_namespace: XLMOD
id: XLMOD:07068

Axiom
annotated source: ethyl trifluoromethanesulfonate
annotated property: definition
annotated target: Ethyl trifluoromethanesulfonate.
database_cross_reference: CAS:425-75-2
database_cross_reference: ChemSpiderID:61241
database_cross_reference: ChemicalBookNo:CB4332659
database_cross_reference: PubChem_Compound:67924

trichloroacetyl chloride
type: Class
subclass of: acylation reagent
definition: Trichloroacetyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:07069

Axiom
annotated source: trichloroacetyl chloride
annotated property: definition
annotated target: Trichloroacetyl chloride.
database_cross_reference: CAS:76-02-8
database_cross_reference: ChemSpiderID:6180
database_cross_reference: ChemicalBookNo:CB6854254
database_cross_reference: PubChem_Compound:6420

2-Thenoyltrifluoroacetone
type: Class
subclass of: acylation reagent
definition: 2-Thenoyltrifluoroacetone.
has_obo_namespace: XLMOD
id: XLMOD:07070

Axiom
annotated source: 2-Thenoyltrifluoroacetone
annotated property: definition
annotated target: 2-Thenoyltrifluoroacetone.
database_cross_reference: CAS:326-91-0
database_cross_reference: ChemSpiderID:5399
database_cross_reference: ChemicalBookNo:CB3219722
database_cross_reference: PubChem_Compound:5601

2,2,6,6-Tetramethyl-3,5-heptanedione
type: Class
subclass of: acylation reagent
definition: 2,2,6,6-Tetramethyl-3,5-heptanedione.
has_obo_namespace: XLMOD
id: XLMOD:07071

Axiom
annotated source: 2,2,6,6-Tetramethyl-3,5-heptanedione
annotated property: definition
annotated target: 2,2,6,6-Tetramethyl-3,5-heptanedione.
database_cross_reference: CAS:1118-71-4
database_cross_reference: ChemSpiderID:63866
database_cross_reference: ChemicalBookNo:CB1373637
database_cross_reference: PubChem_Compound:70700

N-Methyl-bis-heptafluorobutyramide
type: Class
subclass of: acylation reagent
definition: N-Methyl-bis-heptafluorobutyramide.
has_obo_namespace: XLMOD
id: XLMOD:07072

Axiom
annotated source: N-Methyl-bis-heptafluorobutyramide
annotated property: definition
annotated target: N-Methyl-bis-heptafluorobutyramide.
database_cross_reference: CAS:73980-71-9
database_cross_reference: ChemSpiderID:519801
database_cross_reference: ChemicalBookNo:CB6699309
database_cross_reference: PubChem_Compound:597974

N,N'-Diisopropyl-O-methylisourea
type: Class
subclass of: acylation reagent
definition: N,N'-Diisopropyl-O-methylisourea.
has_obo_namespace: XLMOD
id: XLMOD:07073

Axiom
annotated source: N,N'-Diisopropyl-O-methylisourea
annotated property: definition
annotated target: N,N'-Diisopropyl-O-methylisourea.
database_cross_reference: CAS:54648-79-2
database_cross_reference: ChemSpiderID:340092
database_cross_reference: ChemicalBookNo:CB4130844
database_cross_reference: PubChem_Compound:383824

3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
type: Class
subclass of: acylation reagent
definition: 3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid.
has_obo_namespace: XLMOD
id: XLMOD:07074

Axiom
annotated source: 3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
annotated property: definition
annotated target: 3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid.
database_cross_reference: CAS:81655-41-6
database_cross_reference: ChemSpiderID:5360910
database_cross_reference: ChemicalBookNo:CB4264981
database_cross_reference: PubChem_Compound:86531

6,6,7,7,8,8,8-Heptafluoro-2,2-dimethyl-3,5-octanedione
type: Class
subclass of: acylation reagent
definition: 6,6,7,7,8,8,8-Heptafluoro-2,2-dimethyl-3,5-octanedione.
has_obo_namespace: XLMOD
id: XLMOD:07075

Axiom
annotated source: 6,6,7,7,8,8,8-Heptafluoro-2,2-dimethyl-3,5-octanedione
annotated property: definition
annotated target: 6,6,7,7,8,8,8-Heptafluoro-2,2-dimethyl-3,5-octanedione.
database_cross_reference: CAS:17587-22-3
database_cross_reference: ChemSpiderID:26612
database_cross_reference: ChemicalBookNo:CB2271873
database_cross_reference: PubChem_Compound:28614

4-Bromophenacyl trifluoro-methanesulfonate
type: Class
subclass of: acylation reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 4-bromophenacyl
definition: 4-Bromophenacyl trifluoro-methanesulfonate.
has_exact_synonym: 4-Bromophenacyl triflate
has_obo_namespace: XLMOD
id: XLMOD:07076

Axiom
annotated source: 4-Bromophenacyl trifluoro-methanesulfonate
annotated property: definition
annotated target: 4-Bromophenacyl trifluoro-methanesulfonate.
database_cross_reference: CAS:93128-04-2
database_cross_reference: ChemSpiderID:111291
database_cross_reference: ChemicalBookNo:CB4137500
database_cross_reference: PubChem_Compound:125008

2,3-Diaminotoluene
type: Class
subclass of: acylation reagent
definition: 2,3-Diaminotoluene.
has_obo_namespace: XLMOD
id: XLMOD:07077

Axiom
annotated source: 2,3-Diaminotoluene
annotated property: definition
annotated target: 2,3-Diaminotoluene.
database_cross_reference: CAS:2687-25-4
database_cross_reference: ChemSpiderID:16633
database_cross_reference: ChemicalBookNo:CB2736932
database_cross_reference: PubChem_Compound:17593

2,6-Diamino-4-pyrimidinone
type: Class
subclass of: acylation reagent
definition: 2,6-Diamino-4-pyrimidinone.
has_obo_namespace: XLMOD
id: XLMOD:07078

Axiom
annotated source: 2,6-Diamino-4-pyrimidinone
annotated property: definition
annotated target: 2,6-Diamino-4-pyrimidinone.
database_cross_reference: CAS:56-06-4
database_cross_reference: ChemSpiderID:2840
database_cross_reference: ChemicalBookNo:CB0174912
database_cross_reference: PubChem_Compound:2944

benzoic acid
type: Class
subclass of: acylation reagent
definition: Benzoic acid.
has_obo_namespace: XLMOD
id: XLMOD:07079

Axiom
annotated source: benzoic acid
annotated property: definition
annotated target: Benzoic acid.
database_cross_reference: CAS:65-85-0
database_cross_reference: ChemSpiderID:238
database_cross_reference: ChemicalBookNo:CB8698780
database_cross_reference: PubChem_Compound:243

tert-Butyl methyl ether
type: Class
subclass of: acylation reagent
definition: Tert-Butyl methyl ether.
has_obo_namespace: XLMOD
id: XLMOD:07080

Axiom
annotated source: tert-Butyl methyl ether
annotated property: definition
annotated target: Tert-Butyl methyl ether.
database_cross_reference: CAS:1634-04-4
database_cross_reference: ChemSpiderID:14672
database_cross_reference: ChemicalBookNo:CB2853178
database_cross_reference: PubChem_Compound:15413

ethyl acetoacetate
type: Class
subclass of: acylation reagent
definition: Ethyl acetoacetate.
has_obo_namespace: XLMOD
id: XLMOD:07081

Axiom
annotated source: ethyl acetoacetate
annotated property: definition
annotated target: Ethyl acetoacetate.
database_cross_reference: CAS:141-97-9
database_cross_reference: ChemSpiderID:13865426
database_cross_reference: ChemicalBookNo:CB0301721
database_cross_reference: PubChem_Compound:8868

(1S)-(+)-Menthyl chloroformate
type: Class
subclass of: acylation reagent
subclass of: chiral derivatization reagent
subclass of: chloroformate reagent
definition: (1S)-(+)-Menthyl chloroformate.
has_obo_namespace: XLMOD
id: XLMOD:07082

Axiom
annotated source: (1S)-(+)-Menthyl chloroformate
annotated property: definition
annotated target: (1S)-(+)-Menthyl chloroformate.
database_cross_reference: CAS:7635-54-3
database_cross_reference: ChemSpiderID:2015131
database_cross_reference: ChemicalBookNo:CB5397503
database_cross_reference: PubChem_Compound:2733329

butylboronic acid
type: Class
subclass of: acylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: boronic acid
definition: Butylboronic acid.
has_obo_namespace: XLMOD
id: XLMOD:07083

Axiom
annotated source: butylboronic acid
annotated property: definition
annotated target: Butylboronic acid.
database_cross_reference: CAS:4426-47-5
database_cross_reference: ChemSpiderID:19286
database_cross_reference: ChemicalBookNo:CB6431756
database_cross_reference: PubChem_Compound:20479

1-(Pentafluoropropionyl) imidazole
type: Class
subclass of: acylation reagent
definition: 1-(Pentafluoropropionyl) imidazole.
has_obo_namespace: XLMOD
id: XLMOD:07084

Axiom
annotated source: 1-(Pentafluoropropionyl) imidazole
annotated property: definition
annotated target: 1-(Pentafluoropropionyl) imidazole.
database_cross_reference: CAS:71735-32-5
database_cross_reference: ChemSpiderID:91097
database_cross_reference: ChemicalBookNo:CB8441122
database_cross_reference: PubChem_Compound:100821

hexafluoroacetylacetone
type: Class
subclass of: acylation reagent
definition: Hexafluoroacetylacetone.
has_exact_synonym: Hexafluoro-2,4-pentanedione
has_obo_namespace: XLMOD
id: XLMOD:07085

Axiom
annotated source: hexafluoroacetylacetone
annotated property: definition
annotated target: Hexafluoroacetylacetone.
database_cross_reference: CAS:1522-22-1
database_cross_reference: ChemSpiderID:21106446
database_cross_reference: ChemicalBookNo:CB8188414
database_cross_reference: PubChem_Compound:73706

2,3,4,5,6-Pentafluorobenzaldehyde
type: Class
subclass of: acylation reagent
definition: 2,3,4,5,6-Pentafluorobenzaldehyde.
has_obo_namespace: XLMOD
id: XLMOD:07086

Axiom
annotated source: 2,3,4,5,6-Pentafluorobenzaldehyde
annotated property: definition
annotated target: 2,3,4,5,6-Pentafluorobenzaldehyde.
database_cross_reference: CAS:653-37-2
database_cross_reference: ChemSpiderID:21106527
database_cross_reference: ChemicalBookNo:CB6754598
database_cross_reference: PubChem_Compound:69558

pentafluorobenzenesulfonyl chloride
type: Class
subclass of: acylation reagent
definition: Pentafluorobenzenesulfonyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:07087

Axiom
annotated source: pentafluorobenzenesulfonyl chloride
annotated property: definition
annotated target: Pentafluorobenzenesulfonyl chloride.
database_cross_reference: CAS:832-53-1
database_cross_reference: ChemSpiderID:63216
database_cross_reference: ChemicalBookNo:CB7243712
database_cross_reference: PubChem_Compound:70026

1,1,1-Trifluoro-2,4-pentanedione
type: Class
subclass of: TFA reagent
definition: 1,1,1-Trifluoro-2,4-pentanedione.
has_obo_namespace: XLMOD
id: XLMOD:07088

Axiom
annotated source: 1,1,1-Trifluoro-2,4-pentanedione
annotated property: definition
annotated target: 1,1,1-Trifluoro-2,4-pentanedione.
database_cross_reference: CAS:367-57-7
database_cross_reference: ChemSpiderID:66573
database_cross_reference: ChemicalBookNo:CB6699233
database_cross_reference: PubChem_Compound:73943

1,1,1-Trifluoroacetone
type: Class
subclass of: TFA reagent
definition: 1,1,1-Trifluoroacetone.
has_obo_namespace: XLMOD
id: XLMOD:07089

Axiom
annotated source: 1,1,1-Trifluoroacetone
annotated property: definition
annotated target: 1,1,1-Trifluoroacetone.
database_cross_reference: CAS:421-50-1
database_cross_reference: ChemSpiderID:21111803
database_cross_reference: ChemicalBookNo:CB4123453
database_cross_reference: PubChem_Compound:9871

4-(Trifluoromethyl)benzoyl chloride
type: Class
subclass of: TFA reagent
definition: 4-(Trifluoromethyl)benzoyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:07090

Axiom
annotated source: 4-(Trifluoromethyl)benzoyl chloride
annotated property: definition
annotated target: 4-(Trifluoromethyl)benzoyl chloride.
database_cross_reference: CAS:329-15-7
database_cross_reference: ChemSpiderID:60927
database_cross_reference: ChemicalBookNo:CB9762316
database_cross_reference: PubChem_Compound:67607

8-Quinolinesulfonyl chloride
type: Class
subclass of: acylation reagent
definition: 8-Quinolinesulfonyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:07091

Axiom
annotated source: 8-Quinolinesulfonyl chloride
annotated property: definition
annotated target: 8-Quinolinesulfonyl chloride.
database_cross_reference: CAS:18704-37-5
database_cross_reference: ChemSpiderID:27177
database_cross_reference: ChemicalBookNo:CB8329163
database_cross_reference: PubChem_Compound:29220

(1R)-(-)-Menthyl chloroformate
type: Class
subclass of: acylation reagent
subclass of: chiral derivatization reagent
subclass of: chloroformate reagent
definition: (1R)-(-)-Menthyl chloroformate.
has_obo_namespace: XLMOD
id: XLMOD:07092

Axiom
annotated source: (1R)-(-)-Menthyl chloroformate
annotated property: definition
annotated target: (1R)-(-)-Menthyl chloroformate.
database_cross_reference: CAS:14602-86-9
database_cross_reference: ChemSpiderID:17206727
database_cross_reference: ChemicalBookNo:CB7248919
database_cross_reference: PubChem_Compound:7014897

phenylboronic acid
type: Class
subclass of: acylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: boronic acid
definition: Phenylboronic acid.
has_obo_namespace: XLMOD
id: XLMOD:07093

Axiom
annotated source: phenylboronic acid
annotated property: definition
annotated target: Phenylboronic acid.
database_cross_reference: CAS:98-80-6
database_cross_reference: ChemSpiderID:60191
database_cross_reference: ChemicalBookNo:CB5323625
database_cross_reference: PubChem_Compound:66827

methylboronic acid
type: Class
subclass of: acylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: boronic acid
definition: Methylboronic acid.
has_obo_namespace: XLMOD
id: XLMOD:07094

Axiom
annotated source: methylboronic acid
annotated property: definition
annotated target: Methylboronic acid.
database_cross_reference: CAS:13061-96-6
database_cross_reference: ChemSpiderID:122904
database_cross_reference: ChemicalBookNo:CB3373202
database_cross_reference: PubChem_Compound:139377

2,3,4,5,6-Pentafluorobenzoic anhydride
type: Class
subclass of: acylation reagent
definition: 2,3,4,5,6-Pentafluorobenzoic anhydride.
has_obo_namespace: XLMOD
id: XLMOD:07095

Axiom
annotated source: 2,3,4,5,6-Pentafluorobenzoic anhydride
annotated property: definition
annotated target: 2,3,4,5,6-Pentafluorobenzoic anhydride.
database_cross_reference: CAS:15989-99-8
database_cross_reference: ChemSpiderID:164254
database_cross_reference: ChemicalBookNo:CB3497119
database_cross_reference: PubChem_Compound:189034

4-(Dimethylamino)benzoyl chloride
type: Class
subclass of: acylation reagent
definition: 4-(Dimethylamino)benzoyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:07096

Axiom
annotated source: 4-(Dimethylamino)benzoyl chloride
annotated property: definition
annotated target: 4-(Dimethylamino)benzoyl chloride.
database_cross_reference: CAS:4755-50-4
database_cross_reference: ChemSpiderID:3601987
database_cross_reference: ChemicalBookNo:CB6399872
database_cross_reference: PubChem_Compound:4400782

boron trifluoride butanol
type: Class
subclass of: boron trifluoride reagent
definition: Boron trifluoride butanol.
has_exact_synonym: BF3-butanol
has_obo_namespace: XLMOD
id: XLMOD:07097

Axiom
annotated source: boron trifluoride butanol
annotated property: definition
annotated target: Boron trifluoride butanol.
database_cross_reference: CAS:7637-07-2
database_cross_reference: ChemSpiderID:6116
database_cross_reference: ChemicalBookNo:CB3238105
database_cross_reference: PubChem_Compound:6356

1,1,1,3,3,3-Hexafluoro-2-propanol
type: Class
subclass of: alkylation reagent
definition: 1,1,1,3,3,3-Hexafluoro-2-propanol.
has_obo_namespace: XLMOD
id: XLMOD:07098

Axiom
annotated source: 1,1,1,3,3,3-Hexafluoro-2-propanol
annotated property: definition
annotated target: 1,1,1,3,3,3-Hexafluoro-2-propanol.
database_cross_reference: CAS:920-66-1
database_cross_reference: ChemSpiderID:10606755
database_cross_reference: ChemicalBookNo:CB3251829
database_cross_reference: PubChem_Compound:13529

2,2,3,3,3-Pentafluoro-1-propanol
type: Class
subclass of: alkylation reagent
definition: 2,2,3,3,3-Pentafluoro-1-propanol.
has_obo_namespace: XLMOD
id: XLMOD:07099

Axiom
annotated source: 2,2,3,3,3-Pentafluoro-1-propanol
annotated property: definition
annotated target: 2,2,3,3,3-Pentafluoro-1-propanol.
database_cross_reference: CAS:422-05-9
database_cross_reference: ChemSpiderID:9488
database_cross_reference: ChemicalBookNo:CB9689963
database_cross_reference: PubChem_Compound:9872

2,3,5,6-Tetrafluoro-4-ethanol(trifluoromethyl)benzyl bromide
type: Class
subclass of: alkylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzyl bromide reactive group
definition: 2,3,5,6-Tetrafluoro-4-ethanol(trifluoromethyl)benzyl bromide.
has_obo_namespace: XLMOD
id: XLMOD:07100

Axiom
annotated source: 2,3,5,6-Tetrafluoro-4-ethanol(trifluoromethyl)benzyl bromide
annotated property: definition
annotated target: 2,3,5,6-Tetrafluoro-4-ethanol(trifluoromethyl)benzyl bromide.
database_cross_reference: CAS:76437-40-6
database_cross_reference: ChemSpiderID:112859
database_cross_reference: ChemicalBookNo:CB1682115
database_cross_reference: PubChem_Compound:127137

2,3-Dihydroxy-biphenyl
type: Class
subclass of: alkylation reagent
definition: 2,3-Dihydroxy-biphenyl.
has_obo_namespace: XLMOD
id: XLMOD:07101

Axiom
annotated source: 2,3-Dihydroxy-biphenyl
annotated property: definition
annotated target: 2,3-Dihydroxy-biphenyl.
database_cross_reference: CAS:1133-63-7
database_cross_reference: ChemSpiderID:249
database_cross_reference: ChemicalBookNo:CB0302647
database_cross_reference: PubChem_Compound:254

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
type: Class
subclass of: alkylation reagent
definition: O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride.
has_exact_synonym: Florox reagent
has_obo_namespace: XLMOD
id: XLMOD:07102

Axiom
annotated source: O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
annotated property: definition
annotated target: O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride.
database_cross_reference: CAS:57981-02-9
database_cross_reference: ChemSpiderID:109062
database_cross_reference: ChemicalBookNo:CB8307815
database_cross_reference: PubChem_Compound:122307

pentafluoroiodoethane
type: Class
subclass of: alkylation reagent
definition: Pentafluoroiodoethane.
has_obo_namespace: XLMOD
id: XLMOD:07103

Axiom
annotated source: pentafluoroiodoethane
annotated property: definition
annotated target: Pentafluoroiodoethane.
database_cross_reference: CAS:354-64-3
database_cross_reference: ChemSpiderID:9259
database_cross_reference: ChemicalBookNo:CB1226715
database_cross_reference: PubChem_Compound:9636

tetrabutylammoniumtetrabutylborate
type: Class
subclass of: alkylation reagent
definition: Tetrabutylammoniumtetrabutylborate.
has_obo_namespace: XLMOD
id: XLMOD:07104

Axiom
annotated source: tetrabutylammoniumtetrabutylborate
annotated property: definition
annotated target: Tetrabutylammoniumtetrabutylborate.
database_cross_reference: CAS:23231-91-6
database_cross_reference: ChemSpiderID:9298821
database_cross_reference: ChemicalBookNo:CB9765711
database_cross_reference: PubChem_Compound:11123692

trimethylboroxine
type: Class
subclass of: alkylation reagent
definition: Trimethylboroxine.
has_obo_namespace: XLMOD
id: XLMOD:07105

Axiom
annotated source: trimethylboroxine
annotated property: definition
annotated target: Trimethylboroxine.
database_cross_reference: CAS:823-96-1
database_cross_reference: ChemSpiderID:499140
database_cross_reference: ChemicalBookNo:499140
database_cross_reference: PubChem_Compound:574072

boron trifluoride propanol
type: Class
subclass of: boron trifluoride reagent
definition: Boron trifluoride propanol.
has_exact_synonym: BF3-propanol
has_obo_namespace: XLMOD
id: XLMOD:07107

Axiom
annotated source: boron trifluoride propanol
annotated property: definition
annotated target: Boron trifluoride propanol.
database_cross_reference: CAS:762-48-1
database_cross_reference: ChemSpiderID:11428571
database_cross_reference: ChemicalBookNo:CB7289428

4-Bromobenzyl bromide
type: Class
subclass of: arylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzyl bromide reactive group
definition: 4-Bromobenzyl bromide.
has_obo_namespace: XLMOD
id: XLMOD:07108

Axiom
annotated source: 4-Bromobenzyl bromide
annotated property: definition
annotated target: 4-Bromobenzyl bromide.
database_cross_reference: CAS:589-15-1
database_cross_reference: ChemSpiderID:61802
database_cross_reference: ChemicalBookNo:CB8313784
database_cross_reference: PubChem_Compound:68527

N,N-Dimethylformamidediethyl acetal
type: Class
subclass of: N,N-Dimethylformamidedialkyl acetal
definition: N,N-Dimethylformamidediethyl acetal.
has_exact_synonym: 1,1-Diethoxy-N,N-dimethylmethanamine
has_obo_namespace: XLMOD
id: XLMOD:07109

Axiom
annotated source: N,N-Dimethylformamidediethyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidediethyl acetal.
database_cross_reference: CAS:1188-33-6
database_cross_reference: ChemSpiderID:64076
database_cross_reference: ChemicalBookNo:CB6665913
database_cross_reference: PubChem_Compound:70913

N,N-Dimethylformamidedibutyl acetal
type: Class
subclass of: N,N-Dimethylformamidedialkyl acetal
definition: N,N-Dimethylformamidedibutyl acetal.
has_exact_synonym: 1,1-Dibutoxy-N,N-dimethylmethanamine
has_obo_namespace: XLMOD
id: XLMOD:07110

Axiom
annotated source: N,N-Dimethylformamidedibutyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidedibutyl acetal.
database_cross_reference: CAS:18503-90-7
database_cross_reference: ChemSpiderID:79103
database_cross_reference: ChemicalBookNo:CB8770217
database_cross_reference: PubChem_Compound:87683

N,N-Dimethylformamidediisopropyl acetal
type: Class
subclass of: N,N-Dimethylformamidedialkyl acetal
definition: N,N-Dimethylformamidediisopropyl acetal.
has_obo_namespace: XLMOD
id: XLMOD:07111

Axiom
annotated source: N,N-Dimethylformamidediisopropyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidediisopropyl acetal.
database_cross_reference: CAS:18503-89-4
database_cross_reference: ChemSpiderID:79102
database_cross_reference: ChemicalBookNo:CB1137822
database_cross_reference: PubChem_Compound:87682

N,N-Dimethylformamidedineopentyl acetal
type: Class
subclass of: N,N-Dimethylformamidedialkyl acetal
definition: N,N-Dimethylformamidedineopentyl acetal.
has_obo_namespace: XLMOD
id: XLMOD:07112

Axiom
annotated source: N,N-Dimethylformamidedineopentyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidedineopentyl acetal.
database_cross_reference: CAS:4909-78-8
database_cross_reference: ChemSpiderID:70980
database_cross_reference: ChemicalBookNo:CB1335538
database_cross_reference: PubChem_Compound:78623

N,N-Dimethylformamidedipropyl acetal
type: Class
subclass of: N,N-Dimethylformamidedialkyl acetal
definition: N,N-Dimethylformamidedipropyl acetal.
has_obo_namespace: XLMOD
id: XLMOD:07113

Axiom
annotated source: N,N-Dimethylformamidedipropyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidedipropyl acetal.
database_cross_reference: CAS:6006-65-1
database_cross_reference: ChemSpiderID:72355
database_cross_reference: ChemicalBookNo:CB4137823
database_cross_reference: PubChem_Compound:80105

N,N-Dimethylformamidedi-tert-butyl acetal
type: Class
subclass of: N,N-Dimethylformamidedialkyl acetal
definition: N,N-Dimethylformamidedi-tert-butyl acetal.
has_obo_namespace: XLMOD
id: XLMOD:07114

Axiom
annotated source: N,N-Dimethylformamidedi-tert-butyl acetal
annotated property: definition
annotated target: N,N-Dimethylformamidedi-tert-butyl acetal.
database_cross_reference: CAS:36805-97-7
database_cross_reference: ChemSpiderID:476708
database_cross_reference: ChemicalBookNo:CB5296219
database_cross_reference: PubChem_Compound:547712

nonafluoro-1-iodobutane
type: Class
subclass of: alkylation reagent
definition: Nonafluoro-1-iodobutane.
has_exact_synonym: 1-Iodoperfluorobutane
has_exact_synonym: Perfluorobutyl iodide
has_obo_namespace: XLMOD
id: XLMOD:07115

Axiom
annotated source: nonafluoro-1-iodobutane
annotated property: definition
annotated target: Nonafluoro-1-iodobutane.
database_cross_reference: CAS:423-39-2
database_cross_reference: ChemSpiderID:61234
database_cross_reference: ChemicalBookNo:CB9474482
database_cross_reference: PubChem_Compound:67917

triethyloxonium tetrafluo.owlrate
type: Class
subclass of: trialkyloxonium reagent
definition: Triethyloxonium tetrafluo.owlrate.
has_obo_namespace: XLMOD
id: XLMOD:07116

Axiom
annotated source: triethyloxonium tetrafluo.owlrate
annotated property: definition
annotated target: Triethyloxonium tetrafluo.owlrate.
database_cross_reference: CAS:368-39-8
database_cross_reference: ChemSpiderID:2006158
database_cross_reference: ChemicalBookNo:CB0198800
database_cross_reference: PubChem_Compound:2723982

2,2,2-Trichloroethanol
type: Class
subclass of: alkylation reagent
definition: 2,2,2-Trichloroethanol.
has_obo_namespace: XLMOD
id: XLMOD:07117

Axiom
annotated source: 2,2,2-Trichloroethanol
annotated property: definition
annotated target: 2,2,2-Trichloroethanol.
database_cross_reference: CAS:115-20-8
database_cross_reference: ChemSpiderID:7961
database_cross_reference: ChemicalBookNo:CB7257753
database_cross_reference: PubChem_Compound:8259

triethyloxonium hexafluorophosphate
type: Class
subclass of: trialkyloxonium reagent
definition: Triethyloxonium hexafluorophosphate.
has_obo_namespace: XLMOD
id: XLMOD:07118

Axiom
annotated source: triethyloxonium hexafluorophosphate
annotated property: definition
annotated target: Triethyloxonium hexafluorophosphate.
database_cross_reference: CAS:17950-40-2
database_cross_reference: ChemSpiderID:146692
database_cross_reference: ChemicalBookNo:CB4151711
database_cross_reference: PubChem_Compound:167684

2,2,2-Trifluoroethanol
type: Class
subclass of: alkylation reagent
definition: 2,2,2-Trifluoroethanol.
has_obo_namespace: XLMOD
id: XLMOD:07119

Axiom
annotated source: 2,2,2-Trifluoroethanol
annotated property: definition
annotated target: 2,2,2-Trifluoroethanol.
database_cross_reference: CAS:75-89-8
database_cross_reference: ChemSpiderID:21106169
database_cross_reference: ChemicalBookNo:CB5736665
database_cross_reference: PubChem_Compound:6409

trimethyloxonium tetrafluo.owlrate
type: Class
subclass of: trialkyloxonium reagent
definition: Trimethyloxonium tetrafluo.owlrate.
has_obo_namespace: XLMOD
id: XLMOD:07120

Axiom
annotated source: trimethyloxonium tetrafluo.owlrate
annotated property: definition
annotated target: Trimethyloxonium tetrafluo.owlrate.
database_cross_reference: CAS:420-37-1
database_cross_reference: ChemSpiderID:2016863
database_cross_reference: ChemicalBookNo:CB3184284
database_cross_reference: PubChem_Compound:2735153

2,2-Dimethoxypropane
type: Class
subclass of: alkylation reagent
definition: 2,2-Dimethoxypropane.
has_obo_namespace: XLMOD
id: XLMOD:07121

Axiom
annotated source: 2,2-Dimethoxypropane
annotated property: definition
annotated target: 2,2-Dimethoxypropane.
database_cross_reference: CAS:77-76-9
database_cross_reference: ChemSpiderID:21106033
database_cross_reference: ChemicalBookNo:CB9373512
database_cross_reference: PubChem_Compound:6495

4-Tolylsulfonylmethylnitrosamide
type: Class
subclass of: alkylation reagent
definition: 4-Tolylsulfonylmethylnitrosamide.
has_exact_synonym: Diazald
has_exact_synonym: N-Methyl-N-nitrosotoluene-4-sulphonamide
has_obo_namespace: XLMOD
id: XLMOD:07122

Axiom
annotated source: 4-Tolylsulfonylmethylnitrosamide
annotated property: definition
annotated target: 4-Tolylsulfonylmethylnitrosamide.
database_cross_reference: CAS:80-11-5
database_cross_reference: ChemSpiderID:6376
database_cross_reference: ChemicalBookNo:CB7663729
database_cross_reference: PubChem_Compound:6628

18-Crown-6
type: Class
subclass of: alkylation reagent
definition: 18-Crown-6.
has_obo_namespace: XLMOD
id: XLMOD:07123

Axiom
annotated source: 18-Crown-6
annotated property: definition
annotated target: 18-Crown-6.
database_cross_reference: CAS:17455-13-9
database_cross_reference: ChemSpiderID:26563
database_cross_reference: ChemicalBookNo:CB4445218
database_cross_reference: PubChem_Compound:28557

3-Aminopropyltriethoxysilane
type: Class
subclass of: silylation reagent
definition: 3-Aminopropyltriethoxysilane.
has_exact_synonym: APTES
has_obo_namespace: XLMOD
id: XLMOD:07124

Axiom
annotated source: 3-Aminopropyltriethoxysilane
annotated property: definition
annotated target: 3-Aminopropyltriethoxysilane.
database_cross_reference: CAS:919-30-2
database_cross_reference: ChemSpiderID:12933
database_cross_reference: ChemicalBookNo:CB8686147
database_cross_reference: PubChem_Compound:13521

dansyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: nucleoside reactive
definition: Dansyl chloride.
has_exact_synonym: 5-dimethylamino-1-naphthalenesulfonyl chloride
has_exact_synonym: DNS-Cl
has_obo_namespace: XLMOD
id: XLMOD:09000

Axiom
annotated source: dansyl chloride
annotated property: definition
annotated target: Dansyl chloride.
database_cross_reference: CAS:605-65-2
database_cross_reference: ChemSpiderID:11308
database_cross_reference: ChemicalBookNo:CB5696240
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:14513518

picolinic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Picolinic acid.
has_exact_synonym: PA
has_obo_namespace: XLMOD
id: XLMOD:09001

Axiom
annotated source: picolinic acid
annotated property: definition
annotated target: Picolinic acid.
database_cross_reference: CAS:98-98-6
database_cross_reference: ChemSpiderID:993
database_cross_reference: ChemicalBookNo:CB8196640
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:1018

fusaric acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: Fusaric acid.
has_exact_synonym: FA
has_obo_namespace: XLMOD
id: XLMOD:09002

Axiom
annotated source: fusaric acid
annotated property: definition
annotated target: Fusaric acid.
database_cross_reference: CAS:536-69-6
database_cross_reference: ChemSpiderID:3324
database_cross_reference: ChemicalBookNo:CB4689029
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:3442

dimethylglycine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: Dimethylglycine.
has_exact_synonym: N,N-Dimethylglycine
has_obo_namespace: XLMOD
id: XLMOD:09003

Axiom
annotated source: dimethylglycine
annotated property: definition
annotated target: Dimethylglycine.
database_cross_reference: CAS:1118-68-9
database_cross_reference: ChemSpiderID:653
database_cross_reference: ChemicalBookNo:1118-68-9
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:673

isonicotinoyl azide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Isonicotinoyl azide.
has_exact_synonym: INA
has_exact_synonym: Pyridine-4-carbonyl azide
has_obo_namespace: XLMOD
id: XLMOD:09004

Axiom
annotated source: isonicotinoyl azide
annotated property: definition
annotated target: Isonicotinoyl azide.
database_cross_reference: ChemSpiderID:9875783
database_cross_reference: ChemicalBookNo:CB1385038
database_cross_reference: PMID:23524938
database_cross_reference: PMID:26454158
database_cross_reference: PubChem_Compound:11701058

NA-NHS ester
type: Class
subclass of: LCMS derivatization reagent
definition: N-hydroxysuccinimide esters of N-alkyl(C1-C4)nicotinic acids.
has_obo_namespace: XLMOD
id: XLMOD:09005

Axiom
annotated source: NA-NHS ester
annotated property: definition
annotated target: N-hydroxysuccinimide esters of N-alkyl(C1-C4)nicotinic acids.
database_cross_reference: PMID:16808485
database_cross_reference: PMID:22575224

2-fluoro-1-methylpyridinium p-toluenesulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 2-fluoro-1-methylpyridinium p-toluenesulfonate.
has_exact_synonym: FMP
has_obo_namespace: XLMOD
id: XLMOD:09006

Axiom
annotated source: 2-fluoro-1-methylpyridinium p-toluenesulfonate
annotated property: definition
annotated target: 2-fluoro-1-methylpyridinium p-toluenesulfonate.
database_cross_reference: CAS:58086-67-2
database_cross_reference: ChemSpiderID:150036
database_cross_reference: ChemicalBookNo:CB1142305
database_cross_reference: PMID:23524938

3-nitrophthalic anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
definition: 3-nitrophthalic anhydride.
has_obo_namespace: XLMOD
id: XLMOD:09007

Axiom
annotated source: 3-nitrophthalic anhydride
annotated property: definition
annotated target: 3-nitrophthalic anhydride.
database_cross_reference: CAS:641-70-3
database_cross_reference: ChemSpiderID:20330
database_cross_reference: ChemicalBookNo:CB8116378
database_cross_reference: PMID:23524938
database_cross_reference: PMID:7802865
database_cross_reference: PubChem_Compound:21631

2-hydrazino-1-methylpyridine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 2-hydrazino-1-methylpyridine.
has_exact_synonym: HMP
has_obo_namespace: XLMOD
id: XLMOD:09008

Axiom
annotated source: 2-hydrazino-1-methylpyridine
annotated property: definition
annotated target: 2-hydrazino-1-methylpyridine.
database_cross_reference: ChemSpiderID:21376238
database_cross_reference: PMID:23524938

2-hydrazinopyridine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 2-hydrazinopyridine.
has_exact_synonym: HP
has_obo_namespace: XLMOD
id: XLMOD:09009

Axiom
annotated source: 2-hydrazinopyridine
annotated property: definition
annotated target: 2-hydrazinopyridine.
database_cross_reference: CAS:4930-98-7
database_cross_reference: ChemSpiderID:71000
database_cross_reference: ChemicalBookNo:CB0389206
database_cross_reference: PMID:23524938
database_cross_reference: PMID:26454158
database_cross_reference: PubChem_Compound:78645

dansyl hydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: Dansyl hydrazine.
has_exact_synonym: 5-(Dimethylamino)-1-naphthalenesulfonohydrazide
has_exact_synonym: 5-dimethylaminonaphthalene-1-sulfonyl hydrazine
has_exact_synonym: DH
has_exact_synonym: Dns-Hz
has_obo_namespace: XLMOD
id: XLMOD:09010

Axiom
annotated source: dansyl hydrazine
annotated property: definition
annotated target: Dansyl hydrazine.
database_cross_reference: CAS:33008-06-9
database_cross_reference: ChemSpiderID:85229
database_cross_reference: ChemicalBookNo:CB9236754
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:94442

Girard's reagent P
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Pyridinioacetohydrazide chloride.
has_exact_synonym: 1-(2-hydrazino-2-oxoethyl)pyridinium chloride
has_exact_synonym: 1-(carboxymethyl)pyridium chloride hydrazide
has_exact_synonym: GP
has_exact_synonym: Gir P
has_obo_namespace: XLMOD
id: XLMOD:09011

Axiom
annotated source: Girard's reagent P
annotated property: definition
annotated target: Pyridinioacetohydrazide chloride.
database_cross_reference: CAS:1126-58-5
database_cross_reference: ChemSpiderID:63938
database_cross_reference: ChemicalBookNo:CB2285753
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:70773

Girard's reagent T
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_reactive_with
  some values from: nucleoside reactive
definition: Betaine Hydrazide Hydrochloride.
has_exact_synonym: 1-(carboxymethyl)trimethylammonium chloride hydrazide
has_exact_synonym: GT
has_exact_synonym: Gir T
has_obo_namespace: XLMOD
id: XLMOD:09012

Axiom
annotated source: Girard's reagent T
annotated property: definition
annotated target: Betaine Hydrazide Hydrochloride.
database_cross_reference: CAS:123-46-6
database_cross_reference: ChemSpiderID:60501
database_cross_reference: ChemicalBookNo:CB9414297
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:67156

2,4-dinitrophenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 2,4-dinitrophenyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 2,4-dinitrophenylhydrazine.
has_exact_synonym: DNPH
has_obo_namespace: XLMOD
id: XLMOD:09013

Axiom
annotated source: 2,4-dinitrophenylhydrazine
annotated property: definition
annotated target: 2,4-dinitrophenylhydrazine.
database_cross_reference: CAS:119-26-6
database_cross_reference: ChemSpiderID:3001507
database_cross_reference: ChemicalBookNo:CB4852908
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:3772977

hydroxylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Hydroxylamine.
has_exact_synonym: HA
has_obo_namespace: XLMOD
id: XLMOD:09014

Axiom
annotated source: hydroxylamine
annotated property: definition
annotated target: Hydroxylamine.
database_cross_reference: CAS:7803-49-8
database_cross_reference: ChemSpiderID:766
database_cross_reference: ChemicalBookNo:CB3345090
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:787

4-[2-(Trimethylammonio)ethoxy]anilinium dibromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 4-[2-(Trimethylammonio)ethoxy]anilinium dibromide.
has_exact_synonym: 4-APC
has_obo_namespace: XLMOD
id: XLMOD:09015

Axiom
annotated source: 4-[2-(Trimethylammonio)ethoxy]anilinium dibromide
annotated property: definition
annotated target: 4-[2-(Trimethylammonio)ethoxy]anilinium dibromide.
database_cross_reference: CAS:1076196-38-7
database_cross_reference: ChemSpiderID:29342342
database_cross_reference: ChemicalBookNo:CB32747247
database_cross_reference: PMID:23524938

4-(2-((4-bromophenethyl)dimethylammonio)ethoxy)benzenaminium dibromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 4-(2-((4-bromophenethyl)dimethylammonio)ethoxy)benzenaminium dibromide.
has_exact_synonym: 4-APEBA
has_obo_namespace: XLMOD
id: XLMOD:09016

Axiom
annotated source: 4-(2-((4-bromophenethyl)dimethylammonio)ethoxy)benzenaminium dibromide
annotated property: definition
annotated target: 4-(2-((4-bromophenethyl)dimethylammonio)ethoxy)benzenaminium dibromide.
database_cross_reference: CAS:197305-97-8
database_cross_reference: ChemSpiderID:1064766
database_cross_reference: ChemicalBookNo:CB7444959
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:91826487

D-Cysteine
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: D-Cysteine.
has_obo_namespace: XLMOD
id: XLMOD:09017

Axiom
annotated source: D-Cysteine
annotated property: definition
annotated target: D-Cysteine.
database_cross_reference: CAS:921-01-7
database_cross_reference: ChemSpiderID:83819
database_cross_reference: ChemicalBookNo:CB4407452
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:92851

2-Picolylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 2-Picolylamine.
has_exact_synonym: 2-PA
has_obo_namespace: XLMOD
id: XLMOD:09018

Axiom
annotated source: 2-Picolylamine
annotated property: definition
annotated target: 2-Picolylamine.
database_cross_reference: CAS:3731-51-9
database_cross_reference: ChemSpiderID:18383
database_cross_reference: ChemicalBookNo:CB8853569
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:19509

3-Picolylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-Picolylamine.
has_exact_synonym: 3-PA
has_obo_namespace: XLMOD
id: XLMOD:09019

Axiom
annotated source: 3-Picolylamine
annotated property: definition
annotated target: 3-Picolylamine.
database_cross_reference: CAS:3731-52-0
database_cross_reference: ChemSpiderID:28777
database_cross_reference: ChemicalBookNo:CB2284635
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:31018

3-picolylcarbinol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-picolylcarbinol.
has_obo_namespace: XLMOD
id: XLMOD:09020

Axiom
annotated source: 3-picolylcarbinol
annotated property: definition
annotated target: 3-picolylcarbinol.
database_cross_reference: ChemSpiderID:72714
database_cross_reference: PMID:23524938

3-Hydroxy-1-methyl-piperidine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-Hydroxy-1-methyl-piperidine.
has_obo_namespace: XLMOD
id: XLMOD:09021

Axiom
annotated source: 3-Hydroxy-1-methyl-piperidine
annotated property: definition
annotated target: 3-Hydroxy-1-methyl-piperidine.
database_cross_reference: CAS:3554-74-3
database_cross_reference: ChemSpiderID:88489
database_cross_reference: ChemicalBookNo:CB7340664
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:98016

3-(Hydroxymethyl)-pyridine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-(Hydroxymethyl)-pyridine.
has_obo_namespace: XLMOD
id: XLMOD:09022

Axiom
annotated source: 3-(Hydroxymethyl)-pyridine
annotated property: definition
annotated target: 3-(Hydroxymethyl)-pyridine.
database_cross_reference: CAS:100-55-0
database_cross_reference: ChemSpiderID:7229
database_cross_reference: ChemicalBookNo:CB6384809
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:7510

4-Diazomethylpyridine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 4-Diazomethylpyridine.
has_obo_namespace: XLMOD
id: XLMOD:09023

Axiom
annotated source: 4-Diazomethylpyridine
annotated property: definition
annotated target: 4-Diazomethylpyridine.
database_cross_reference: CAS:26363-69-9
database_cross_reference: ChemSpiderID:57445102
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:12066686

4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: 4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-AE
has_obo_namespace: XLMOD
id: XLMOD:09024

Axiom
annotated source: 4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole.
database_cross_reference: CAS:913253-56-2
database_cross_reference: ChemSpiderID:21377953
database_cross_reference: ChemicalBookNo:CB62720627
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:91247932

1-Butanol hydrochloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 1-Butanol hydrochloride.
has_exact_synonym: Butanol + HCl
has_obo_namespace: XLMOD
id: XLMOD:09025

Axiom
annotated source: 1-Butanol hydrochloride
annotated property: definition
annotated target: 1-Butanol hydrochloride.
database_cross_reference: ChemSpiderID:13206062
database_cross_reference: PMID:23524938

fluorenylmethyloxycarbonyl chloride
type: Class
subclass of: chloroformate reagent
definition: Fluorenylmethyloxycarbonyl chloride.
has_exact_synonym: 1-(9-Fluorenyl)methyl chloroformate
has_exact_synonym: FMOC-Cl
has_obo_namespace: XLMOD
id: XLMOD:09026

Axiom
annotated source: fluorenylmethyloxycarbonyl chloride
annotated property: definition
annotated target: Fluorenylmethyloxycarbonyl chloride.
database_cross_reference: CAS:28920-43-6
database_cross_reference: ChemSpiderID:31647
database_cross_reference: ChemicalBookNo:CB7234569
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:34367

N-Methyl-2-phenylethanamide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: N-Methyl-2-phenylethanamide.
has_obo_namespace: XLMOD
id: XLMOD:09027

Axiom
annotated source: N-Methyl-2-phenylethanamide
annotated property: definition
annotated target: N-Methyl-2-phenylethanamide.
database_cross_reference: CAS:6830-82-6
database_cross_reference: ChemSpiderID:73329
database_cross_reference: ChemicalBookNo:CB4717700
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:81274

2-Bromo-1-(4-(dimethylamino)phenyl)ethanone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 2-Bromo-1-(4-(dimethylamino)phenyl)ethanone.
has_obo_namespace: XLMOD
id: XLMOD:09028

Axiom
annotated source: 2-Bromo-1-(4-(dimethylamino)phenyl)ethanone
annotated property: definition
annotated target: 2-Bromo-1-(4-(dimethylamino)phenyl)ethanone.
database_cross_reference: CAS:37904-72-6
database_cross_reference: ChemSpiderID:125460
database_cross_reference: ChemicalBookNo:CB4113692
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:142225

6-aminoquinolyl-N-hydroxysuccinimidyl carbamate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: carabamate
definition: 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate.
has_exact_synonym: 6-ACQ
has_obo_namespace: XLMOD
id: XLMOD:09029

Axiom
annotated source: 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate
annotated property: definition
annotated target: 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate.
database_cross_reference: ChemSpiderID:2043270
database_cross_reference: PMID:16384748
database_cross_reference: PMID:23524938

3-Pyridyl isothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: 3-Pyridyl isothiocyanate.
has_exact_synonym: 3-Isothiocyanatopyridine
has_obo_namespace: XLMOD
id: XLMOD:09030

Axiom
annotated source: 3-Pyridyl isothiocyanate
annotated property: definition
annotated target: 3-Pyridyl isothiocyanate.
database_cross_reference: CAS:17452-27-6
database_cross_reference: ChemSpiderID:2018885
database_cross_reference: ChemicalBookNo:CB4371720
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:2737242

phenyl isothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: Phenyl isothiocyanate.
has_exact_synonym: Edman's reagent
has_exact_synonym: PITC
has_obo_namespace: XLMOD
id: XLMOD:09031

Axiom
annotated source: phenyl isothiocyanate
annotated property: definition
annotated target: Phenyl isothiocyanate.
database_cross_reference: CAS:103-72-0
database_cross_reference: ChemSpiderID:7390
database_cross_reference: ChemicalBookNo:CB5733806
database_cross_reference: PMID:23524938
database_cross_reference: PMID:26496130
database_cross_reference: PubChem_Compound:7673

isobutyl chloroformate
type: Class
subclass of: chloroformate reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: biphosphonate drug reactive
definition: Isobutyl chloroformate.
has_exact_synonym: IBCF
has_exact_synonym: i-BuCF
has_obo_namespace: XLMOD
id: XLMOD:09032

Axiom
annotated source: isobutyl chloroformate
annotated property: definition
annotated target: Isobutyl chloroformate.
database_cross_reference: CAS:543-27-1
database_cross_reference: ChemSpiderID:56154
database_cross_reference: ChemicalBookNo:CB7165612
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:62365

4-(N,N-Dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: halobenzofurazan
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 4-(N,N-Dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole.
has_exact_synonym: DBD-F
has_obo_namespace: XLMOD
id: XLMOD:09033

Axiom
annotated source: 4-(N,N-Dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(N,N-Dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole.
database_cross_reference: CAS:98358-90-8
database_cross_reference: ChemSpiderID:112705
database_cross_reference: ChemicalBookNo:CB3366336
database_cross_reference: PMID:23524938
database_cross_reference: PMID:27582321
database_cross_reference: PubChem_Compound:126917

4-Bromophenacyl bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 4-bromophenacyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: perfluorinated carboxylic acid reactive
definition: 4-Bromophenacyl bromide.
has_exact_synonym: BPBr
has_exact_synonym: p-Bromophenacyl bromide
has_obo_namespace: XLMOD
id: XLMOD:09034

Axiom
annotated source: 4-Bromophenacyl bromide
annotated property: definition
annotated target: 4-Bromophenacyl bromide.
database_cross_reference: CAS:99-73-0
database_cross_reference: ChemSpiderID:7174
database_cross_reference: ChemicalBookNo:CB4239093
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:7454

ethyl bromoacetate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Ethyl bromoacetate.
has_obo_namespace: XLMOD
id: XLMOD:09035

Axiom
annotated source: ethyl bromoacetate
annotated property: definition
annotated target: Ethyl bromoacetate.
database_cross_reference: CAS:105-36-2
database_cross_reference: ChemSpiderID:7462
database_cross_reference: ChemicalBookNo:CB6852654
database_cross_reference: PMID:23524938
database_cross_reference: PubChem_Compound:7748

(2-[4-aminophenoxy]ethyl)trimethylammonium bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
definition: (2-[4-aminophenoxy]ethyl)trimethylammonium bromide.
has_obo_namespace: XLMOD
id: XLMOD:09036

Axiom
annotated source: (2-[4-aminophenoxy]ethyl)trimethylammonium bromide
annotated property: definition
annotated target: (2-[4-aminophenoxy]ethyl)trimethylammonium bromide.
database_cross_reference: ChemSpiderID:24770517
database_cross_reference: PMID:22191594

hydroxylammonium chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
definition: Hydroxylammonium chloride.
has_obo_namespace: XLMOD
id: XLMOD:09037

Axiom
annotated source: hydroxylammonium chloride
annotated property: definition
annotated target: Hydroxylammonium chloride.
database_cross_reference: CAS:5470-11-1
database_cross_reference: ChemSpiderID:391543
database_cross_reference: ChemicalBookNo:CB8128885
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:443297

4-Bromobenzenesulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
definition: 4-Bromobenzenesulfonyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:09038

Axiom
annotated source: 4-Bromobenzenesulfonyl chloride
annotated property: definition
annotated target: 4-Bromobenzenesulfonyl chloride.
database_cross_reference: CAS:98-58-8
database_cross_reference: ChemSpiderID:7118
database_cross_reference: ChemicalBookNo:CB8443863
database_cross_reference: PMID:22191594

7-fluoro-4-nitrobenzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: 7-fluoro-4-nitrobenzoxadiazole.
has_exact_synonym: NBD-F
has_obo_namespace: XLMOD
id: XLMOD:09039

Axiom
annotated source: 7-fluoro-4-nitrobenzoxadiazole
annotated property: definition
annotated target: 7-fluoro-4-nitrobenzoxadiazole.
database_cross_reference: ChemSpiderID:21375215
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:53744831

diacetyl-L-tartaric anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Diacetyl-L-tartaric anhydride.
has_exact_synonym: DATAAN
has_exact_synonym: DATAN
has_obo_namespace: XLMOD
id: XLMOD:09040

Axiom
annotated source: diacetyl-L-tartaric anhydride
annotated property: definition
annotated target: Diacetyl-L-tartaric anhydride.
database_cross_reference: CAS:6283-74-5
database_cross_reference: ChemSpiderID:448369
database_cross_reference: ChemicalBookNo:CB0717661
database_cross_reference: PMID:22191594
database_cross_reference: PMID:26496130
database_cross_reference: PubChem_Compound:102020809

pentafluorophenacyl trifluoromethanesulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: phenacyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Pentafluorophenacyl trifluoromethanesulfonate.
has_obo_namespace: XLMOD
id: XLMOD:09041

Axiom
annotated source: pentafluorophenacyl trifluoromethanesulfonate
annotated property: definition
annotated target: Pentafluorophenacyl trifluoromethanesulfonate.
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:86038332

propyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: Propyl chloroformate.
has_exact_synonym: PrCl
has_obo_namespace: XLMOD
id: XLMOD:09042

Axiom
annotated source: propyl chloroformate
annotated property: definition
annotated target: Propyl chloroformate.
database_cross_reference: CAS:109-61-5
database_cross_reference: ChemSpiderID:7707
database_cross_reference: ChemicalBookNo:CB9852781
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:7998

12,4-dinitrofluorobenzene
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: 12,4-dinitrofluorobenzene.
has_obo_namespace: XLMOD
id: XLMOD:09043

Axiom
annotated source: 12,4-dinitrofluorobenzene
annotated property: definition
annotated target: 12,4-dinitrofluorobenzene.
database_cross_reference: CAS:70-34-8
database_cross_reference: ChemSpiderID:21106037
database_cross_reference: ChemicalBookNo:CB9442373
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:6264

trimethylsilyldiazomethane
type: Class
subclass of: LCMS derivatization reagent
subclass of: TMS reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: biphosphonate drug reactive
definition: Trimethylsilyldiazomethane.
has_exact_synonym: TMS-DAM
has_exact_synonym: TMS-DM
has_obo_namespace: XLMOD
id: XLMOD:09044

Axiom
annotated source: trimethylsilyldiazomethane
annotated property: definition
annotated target: Trimethylsilyldiazomethane.
database_cross_reference: CAS:18107-18-1
database_cross_reference: ChemSpiderID:146699
database_cross_reference: ChemicalBookNo:CB9432840
database_cross_reference: PMID:19525080
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:167693

trimethyl orthoacetate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: biphosphonate drug reactive
definition: 1,1,1-Trimethoxyethane.
has_obo_namespace: XLMOD
id: XLMOD:09045

Axiom
annotated source: trimethyl orthoacetate
annotated property: definition
annotated target: 1,1,1-Trimethoxyethane.
database_cross_reference: CAS:1445-45-0
database_cross_reference: ChemSpiderID:14322
database_cross_reference: ChemicalBookNo:CB5759743
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:15050

3-(Perfluorooctyl)propylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-(Perfluorooctyl)propylamine.
has_exact_synonym: Heptadecafluoroundecylamine
has_obo_namespace: XLMOD
id: XLMOD:09046

Axiom
annotated source: 3-(Perfluorooctyl)propylamine
annotated property: definition
annotated target: 3-(Perfluorooctyl)propylamine.
database_cross_reference: CAS:139175-50-1
database_cross_reference: ChemSpiderID:8918555
database_cross_reference: ChemicalBookNo:CB8736444
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:10743224

dimethylaminoethanol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Dimethylaminoethanol.
has_exact_synonym: DMAE
has_exact_synonym: Deanol
has_obo_namespace: XLMOD
id: XLMOD:09047

Axiom
annotated source: dimethylaminoethanol
annotated property: definition
annotated target: Dimethylaminoethanol.
database_cross_reference: CAS:108-01-0
database_cross_reference: ChemSpiderID:8488535
database_cross_reference: ChemicalBookNo:CB6256870
database_cross_reference: PMID:22191594
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:7902

4-nitrobenzyl bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: arylation reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzyl bromide reactive group
definition: 4-nitrobenzyl bromide.
has_exact_synonym: 4-NBB
has_exact_synonym: p-nitrobenzyl bromide
has_obo_namespace: XLMOD
id: XLMOD:09048

Axiom
annotated source: 4-nitrobenzyl bromide
annotated property: definition
annotated target: 4-nitrobenzyl bromide.
database_cross_reference: CAS:100-11-8
database_cross_reference: ChemSpiderID:59402
database_cross_reference: ChemicalBookNo:CB5485712
database_cross_reference: PMID:3394930
database_cross_reference: PubChem_Compound:66011

2,3-pyridinedicarboxylic anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 2,3-pyridinedicarboxylic anhydride.
has_exact_synonym: Furo(3,4-B)Pyridine-5,7-dione
has_obo_namespace: XLMOD
id: XLMOD:09049

Axiom
annotated source: 2,3-pyridinedicarboxylic anhydride
annotated property: definition
annotated target: 2,3-pyridinedicarboxylic anhydride.
database_cross_reference: CAS:699-98-9
database_cross_reference: ChemSpiderID:62889
database_cross_reference: ChemicalBookNo:CB5268658
database_cross_reference: PMID:22191594

ethoxyamine hydrochloride
type: Class
subclass of: alkylation reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Ethoxyamine hydrochloride.
has_exact_synonym: Ethylhydroxylamine hydrochloride
has_obo_namespace: XLMOD
id: XLMOD:09050

Axiom
annotated source: ethoxyamine hydrochloride
annotated property: definition
annotated target: Ethoxyamine hydrochloride.
database_cross_reference: CAS:3332-29-4
database_cross_reference: ChemSpiderID:69303
database_cross_reference: ChemicalBookNo:CB0126027
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:76850

4-(N,N-Dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 4-(N,N-Dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole.
has_exact_synonym: 4-(N,N-Dimethylsulfamoyl)-7-hydrazino-benzofurazan
has_exact_synonym: DBD-H
has_obo_namespace: XLMOD
id: XLMOD:09051

Axiom
annotated source: 4-(N,N-Dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(N,N-Dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole.
database_cross_reference: CAS:131467-86-2
database_cross_reference: ChemSpiderID:116132
database_cross_reference: ChemicalBookNo:CB8688813
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:131382

1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 2,4-dinitrophenyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine.
has_exact_synonym: 1-(2,4-dinitro-5-fluorophenyl)-4-methylpiperazine
has_exact_synonym: PPZ
has_obo_namespace: XLMOD
id: XLMOD:09052

Axiom
annotated source: 1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine
annotated property: definition
annotated target: 1-(5-Fluoro-2,4-dinitrophenyl)-4-methylpiperazine.
database_cross_reference: ChemSpiderID:17350721
database_cross_reference: PMID:22191594
database_cross_reference: PMID:26454158

4-nitrobenzoyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: acyl chloride
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 4-nitrobenzoyl chloride.
has_exact_synonym: 4-NBC
has_obo_namespace: XLMOD
id: XLMOD:09053

Axiom
annotated source: 4-nitrobenzoyl chloride
annotated property: definition
annotated target: 4-nitrobenzoyl chloride.
database_cross_reference: CAS:122-04-3
database_cross_reference: ChemSpiderID:8188
database_cross_reference: ChemicalBookNo:CB2182076
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:8502

pyridine-3-sulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Pyridine-3-sulfonyl chloride.
has_exact_synonym: PSCl
has_exact_synonym: chloro-3-pyridylsulfone
has_exact_synonym: pyridinium-3-sulfonyl chloride
has_obo_namespace: XLMOD
id: XLMOD:09054

Axiom
annotated source: pyridine-3-sulfonyl chloride
annotated property: definition
annotated target: Pyridine-3-sulfonyl chloride.
database_cross_reference: CAS:16133-25-8
database_cross_reference: ChemSpiderID:2415634
database_cross_reference: ChemicalBookNo:CB5153121
database_cross_reference: PMID:22191594
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:3164136

methyl acrylate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: Methyl acrylate.
has_obo_namespace: XLMOD
id: XLMOD:09055

Axiom
annotated source: methyl acrylate
annotated property: definition
annotated target: Methyl acrylate.
database_cross_reference: CAS:96-33-3
database_cross_reference: ChemSpiderID:7022
database_cross_reference: ChemicalBookNo:CB8669773
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:7294

iodoacetic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: Iodoacetic acid.
has_obo_namespace: XLMOD
id: XLMOD:09056

Axiom
annotated source: iodoacetic acid
annotated property: definition
annotated target: Iodoacetic acid.
database_cross_reference: CAS:64-69-7
database_cross_reference: ChemSpiderID:5050
database_cross_reference: ChemicalBookNo:CB3854071
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:5240

2-Bromo-3'-methoxyacetophenone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 2-Bromo-3'-methoxyacetophenone.
has_obo_namespace: XLMOD
id: XLMOD:09057

Axiom
annotated source: 2-Bromo-3'-methoxyacetophenone
annotated property: definition
annotated target: 2-Bromo-3'-methoxyacetophenone.
database_cross_reference: CAS:5000-65-7
database_cross_reference: ChemSpiderID:91526
database_cross_reference: ChemicalBookNo:CB3100727
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:101294

monobromobimane
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: Monobromobimane.
has_obo_namespace: XLMOD
id: XLMOD:09058

Axiom
annotated source: monobromobimane
annotated property: definition
annotated target: Monobromobimane.
database_cross_reference: CAS:71418-44-5
database_cross_reference: ChemSpiderID:102775
database_cross_reference: ChemicalBookNo:CB0729365
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:114810

4-bromo-phenacyl-bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 4-bromophenacyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 4-bromo-phenacyl-bromide.
has_exact_synonym: 2,4'-Dibromoacetophenone
has_exact_synonym: p-BPB
has_exact_synonym: p-bromo-phenacyl-bromide
has_obo_namespace: XLMOD
id: XLMOD:09059

Axiom
annotated source: 4-bromo-phenacyl-bromide
annotated property: definition
annotated target: 4-bromo-phenacyl-bromide.
database_cross_reference: CAS:99-73-0
database_cross_reference: ChemSpiderID:7174
database_cross_reference: ChemicalBookNo:CB4239093
database_cross_reference: PMID:22191594
database_cross_reference: PubChem_Compound:7454

4-bromomethyl-7-methoxycoumarin
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: nucleoside reactive
definition: 4-bromomethyl-7-methoxycoumarin.
has_exact_synonym: BMC
has_exact_synonym: Br-MMC
has_exact_synonym: BrMMC
has_obo_namespace: XLMOD
id: XLMOD:09060

Axiom
annotated source: 4-bromomethyl-7-methoxycoumarin
annotated property: definition
annotated target: 4-bromomethyl-7-methoxycoumarin.
database_cross_reference: CAS:35231-44-8
database_cross_reference: ChemSpiderID:108742
database_cross_reference: ChemicalBookNo:CB6345309
database_cross_reference: PMID:15897015
database_cross_reference: PMID:19525080
database_cross_reference: PMID:22191594
database_cross_reference: PMID:3394930
database_cross_reference: PubChem_Compound:121894

Cookson type reagent
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-substituted 1,2,4-triazoline-3,5-dione (TAD).
has_obo_namespace: XLMOD
id: XLMOD:09061

Axiom
annotated source: Cookson type reagent
annotated property: definition
annotated target: 4-substituted 1,2,4-triazoline-3,5-dione (TAD).
database_cross_reference: PMID:14598004

4-(4'-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-(4'-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione.
has_exact_synonym: DAPTAD
has_obo_namespace: XLMOD
id: XLMOD:09062

Axiom
annotated source: 4-(4'-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione
annotated property: definition
annotated target: 4-(4'-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione.
database_cross_reference: PMID:24097402

4-Phenyl-1,2,4-triazole-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-Phenyl-1,2,4-triazole-3,5-dione.
has_exact_synonym: PTAD
has_obo_namespace: XLMOD
id: XLMOD:09063

Axiom
annotated source: 4-Phenyl-1,2,4-triazole-3,5-dione
annotated property: definition
annotated target: 4-Phenyl-1,2,4-triazole-3,5-dione.
database_cross_reference: CAS:4233-33-4
database_cross_reference: ChemSpiderID:70304
database_cross_reference: ChemicalBookNo:CB3769656
database_cross_reference: PMID:14598004
database_cross_reference: PMID:26454158

4-[2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl]-TAD
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-[2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl]-TAD.
has_exact_synonym: DMEQTAD
has_obo_namespace: XLMOD
id: XLMOD:09064

Axiom
annotated source: 4-[2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl]-TAD
annotated property: definition
annotated target: 4-[2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl]-TAD.
database_cross_reference: CAS:132788-52-4
database_cross_reference: ChemSpiderID:116261
database_cross_reference: ChemicalBookNo:CB9453782
database_cross_reference: PMID:17077543
database_cross_reference: PMID:27511712
database_cross_reference: PubChem_Compound:131554

4-[4-(6-methoxy-2-benzoxazolyl)phenyl]-1,2,4-triazoline-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-[4-(6-methoxy-2-benzoxazolyl)phenyl]-1,2,4-triazoline-3,5-dione.
has_exact_synonym: MBOTAD
has_obo_namespace: XLMOD
id: XLMOD:09065

Axiom
annotated source: 4-[4-(6-methoxy-2-benzoxazolyl)phenyl]-1,2,4-triazoline-3,5-dione
annotated property: definition
annotated target: 4-[4-(6-methoxy-2-benzoxazolyl)phenyl]-1,2,4-triazoline-3,5-dione.
database_cross_reference: PMID:15897015
database_cross_reference: PMID:27511712

4-(4-Nitrophenyl)-1,2,4-triazole-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 4-nitrophenyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-(4-Nitrophenyl)-1,2,4-triazole-3,5-dione.
has_exact_synonym: NPTAD
has_obo_namespace: XLMOD
id: XLMOD:09066

Axiom
annotated source: 4-(4-Nitrophenyl)-1,2,4-triazole-3,5-dione
annotated property: definition
annotated target: 4-(4-Nitrophenyl)-1,2,4-triazole-3,5-dione.
database_cross_reference: CAS:13274-75-4
database_cross_reference: ChemSpiderID:9542917
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:11368000

edaravone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carbohydrate reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: Edaravone.
has_exact_synonym: 1-phenyl-3-methyl-5-pyrazolone
has_exact_synonym: PMP
has_obo_namespace: XLMOD
id: XLMOD:09067

Axiom
annotated source: edaravone
annotated property: definition
annotated target: Edaravone.
database_cross_reference: CAS:89-25-8
database_cross_reference: ChemSpiderID:3881
database_cross_reference: ChemicalBookNo:CB1287462
database_cross_reference: PMID:20382108
database_cross_reference: PubChem_Compound:4021

tris(trimethoxyphenyl)phosphonium compound
type: Class
subclass of: LCMS derivatization reagent
definition: Tris(trimethoxyphenyl)phosphonium compound.
has_exact_synonym: TMPP compound
has_obo_namespace: XLMOD
id: XLMOD:09068

Axiom
annotated source: tris(trimethoxyphenyl)phosphonium compound
annotated property: definition
annotated target: Tris(trimethoxyphenyl)phosphonium compound.
database_cross_reference: PMID:11857728

1S-pentafluorophenyl tris(2,4,6-trimethoxyphenyl)phosphonium acetate bromide
type: Class
subclass of: chiral derivatization reagent
subclass of: tris(trimethoxyphenyl)phosphonium compound
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 1S-pentafluorophenyl tris(2,4,6-trimethoxyphenyl)phosphonium acetate bromide.
has_exact_synonym: TMPP-AcPFP
has_obo_namespace: XLMOD
id: XLMOD:09069

Axiom
annotated source: 1S-pentafluorophenyl tris(2,4,6-trimethoxyphenyl)phosphonium acetate bromide
annotated property: definition
annotated target: 1S-pentafluorophenyl tris(2,4,6-trimethoxyphenyl)phosphonium acetate bromide.
database_cross_reference: PMID:12590398

(4-hydrazino-4-oxobutyl) [tris(2,4,6-trimethoxyphenyl)phosphonium bromide
type: Class
subclass of: tris(trimethoxyphenyl)phosphonium compound
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
definition: (4-hydrazino-4-oxobutyl) [tris(2,4,6-trimethoxyphenyl)phosphonium bromide.
has_exact_synonym: TMPP-PrG
has_obo_namespace: XLMOD
id: XLMOD:09070

Axiom
annotated source: (4-hydrazino-4-oxobutyl) [tris(2,4,6-trimethoxyphenyl)phosphonium bromide
annotated property: definition
annotated target: (4-hydrazino-4-oxobutyl) [tris(2,4,6-trimethoxyphenyl)phosphonium bromide.
database_cross_reference: PMID:12590398

Tris(2,4,6,-trimethoxyphenyl)phosphonium acetic acid
type: Class
subclass of: tris(trimethoxyphenyl)phosphonium compound
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: cholesterol reactive
definition: Tris(2,4,6,-trimethoxyphenyl)phosphonium acetic acid.
has_exact_synonym: TMPP-AA
has_exact_synonym: TMPP-AcCOOH
has_obo_namespace: XLMOD
id: XLMOD:09071

Axiom
annotated source: Tris(2,4,6,-trimethoxyphenyl)phosphonium acetic acid
annotated property: definition
annotated target: Tris(2,4,6,-trimethoxyphenyl)phosphonium acetic acid.
database_cross_reference: PMID:19449318

Tris(2,4,6,-trimethoxyphenyl)phosphonium ethanoic acid bromide
type: Class
subclass of: tris(trimethoxyphenyl)phosphonium compound
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: Tris(2,4,6,-trimethoxyphenyl)phosphonium ethanoic acid bromide.
has_exact_synonym: TMPP-MeCOOH
has_obo_namespace: XLMOD
id: XLMOD:09072

Axiom
annotated source: Tris(2,4,6,-trimethoxyphenyl)phosphonium ethanoic acid bromide
annotated property: definition
annotated target: Tris(2,4,6,-trimethoxyphenyl)phosphonium ethanoic acid bromide.
database_cross_reference: PMID:11857728

Tris(2,4,6,-trimethoxyphenyl)phosphonium propionic acid bromide
type: Class
subclass of: tris(trimethoxyphenyl)phosphonium compound
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: Tris(2,4,6,-trimethoxyphenyl)phosphonium propionic acid bromide.
has_exact_synonym: TMPP-PrCOOH
has_obo_namespace: XLMOD
id: XLMOD:09073

Axiom
annotated source: Tris(2,4,6,-trimethoxyphenyl)phosphonium propionic acid bromide
annotated property: definition
annotated target: Tris(2,4,6,-trimethoxyphenyl)phosphonium propionic acid bromide.
database_cross_reference: PMID:11857728

Tris(2,4,6,-trimethoxyphenyl)phosphonium propylamine bromide
type: Class
subclass of: tris(trimethoxyphenyl)phosphonium compound
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: Tris(2,4,6,-trimethoxyphenyl)phosphonium propylamine bromide.
has_exact_synonym: TMPP-PrNH2
has_obo_namespace: XLMOD
id: XLMOD:09074

Axiom
annotated source: Tris(2,4,6,-trimethoxyphenyl)phosphonium propylamine bromide
annotated property: definition
annotated target: Tris(2,4,6,-trimethoxyphenyl)phosphonium propylamine bromide.
database_cross_reference: PMID:11857728

benzoic anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
definition: Benzoic anhydride.
has_obo_namespace: XLMOD
id: XLMOD:09075

Axiom
annotated source: benzoic anhydride
annotated property: definition
annotated target: Benzoic anhydride.
database_cross_reference: CAS:93-97-0
database_cross_reference: ChemSpiderID:6899
database_cross_reference: ChemicalBookNo:CB1260942
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:7167

propionic anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
definition: Propionic anhydride.
has_obo_namespace: XLMOD
id: XLMOD:09076

Axiom
annotated source: propionic anhydride
annotated property: definition
annotated target: Propionic anhydride.
database_cross_reference: CAS:123-62-6
database_cross_reference: ChemSpiderID:29003
database_cross_reference: ChemicalBookNo:CB7852974
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:31263

4-toluenesulfonhydrazide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: 4-toluenesulfonhydrazide.
has_exact_synonym: 4-Methylbenzenesulfonhydrazide
has_exact_synonym: TSH
has_exact_synonym: p-toluenesulfonhydrazide
has_obo_namespace: XLMOD
id: XLMOD:09077

Axiom
annotated source: 4-toluenesulfonhydrazide
annotated property: definition
annotated target: 4-toluenesulfonhydrazide.
database_cross_reference: CAS:1576-35-8
database_cross_reference: ChemSpiderID:14566
database_cross_reference: ChemicalBookNo:CB6156664
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:15303

2-(N,N-dimethyl-amino)ethyl acrylate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 2-(N,N-dimethyl-amino)ethyl acrylate.
has_exact_synonym: DMAE acrylate
has_obo_namespace: XLMOD
id: XLMOD:09078

Axiom
annotated source: 2-(N,N-dimethyl-amino)ethyl acrylate
annotated property: definition
annotated target: 2-(N,N-dimethyl-amino)ethyl acrylate.
database_cross_reference: CAS:924-99-2
database_cross_reference: ChemSpiderID:16195
database_cross_reference: ChemicalBookNo:CB1468951
database_cross_reference: PMID:15897015

1-naphthylisothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: 1-Naphthylisothiocyanate.
has_exact_synonym: NIT
has_obo_namespace: XLMOD
id: XLMOD:09079

Axiom
annotated source: 1-naphthylisothiocyanate
annotated property: definition
annotated target: 1-Naphthylisothiocyanate.
database_cross_reference: CAS:551-06-4
database_cross_reference: ChemSpiderID:10609
database_cross_reference: ChemicalBookNo:CB8696418
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:11080

sulfur trioxide pyridine complex
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
definition: Sulfur trioxide pyridine complex.
has_obo_namespace: XLMOD
id: XLMOD:09080

Axiom
annotated source: sulfur trioxide pyridine complex
annotated property: definition
annotated target: Sulfur trioxide pyridine complex.
database_cross_reference: CAS:26412-87-3
database_cross_reference: ChemSpiderID:147422
database_cross_reference: ChemicalBookNo:CB9284694
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:168533

sulfur trioxide N,N-dimethyl-formamide complex
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
definition: Sulfur trioxide N,N-dimethyl-formamide complex.
has_obo_namespace: XLMOD
id: XLMOD:09081

Axiom
annotated source: sulfur trioxide N,N-dimethyl-formamide complex
annotated property: definition
annotated target: Sulfur trioxide N,N-dimethyl-formamide complex.
database_cross_reference: CAS:29584-42-7
database_cross_reference: ChemicalBookNo:CB0234621
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:169056

2-Acrylamido-2-methyl-1-propanesulfonic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 2-acrylamino-2-methyl-propanesulfonic acid.
has_exact_synonym: AMDSA
has_obo_namespace: XLMOD
id: XLMOD:09082

Axiom
annotated source: 2-Acrylamido-2-methyl-1-propanesulfonic acid
annotated property: definition
annotated target: 2-acrylamino-2-methyl-propanesulfonic acid.
database_cross_reference: CAS:15214-89-8
database_cross_reference: ChemSpiderID:58836
database_cross_reference: ChemicalBookNo:CB3470952
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:65360

benzyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: acyl chloride
definition: Benzyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:09083

Axiom
annotated source: benzyl chloride
annotated property: definition
annotated target: Benzyl chloride.
database_cross_reference: CAS:100-44-7
database_cross_reference: ChemSpiderID:13840690
database_cross_reference: ChemicalBookNo:CB1852583
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:7503

acetic anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
definition: Acetic anhydride.
has_exact_synonym: Ethanoic anhydride
has_obo_namespace: XLMOD
id: XLMOD:09084

Axiom
annotated source: acetic anhydride
annotated property: definition
annotated target: Acetic anhydride.
database_cross_reference: CAS:108-24-7
database_cross_reference: ChemSpiderID:7630
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:7918

N-methyl-4-hydrazino-7-nitrobenzofurazan
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: N-methyl-4-hydrazino-7-nitrobenzofurazan.
has_exact_synonym: 4-(1-Methylhydrazino)-7-nitrobenzofurazan
has_exact_synonym: MNBDH
has_obo_namespace: XLMOD
id: XLMOD:09085

Axiom
annotated source: N-methyl-4-hydrazino-7-nitrobenzofurazan
annotated property: definition
annotated target: N-methyl-4-hydrazino-7-nitrobenzofurazan.
database_cross_reference: CAS:214147-22-5
database_cross_reference: ChemSpiderID:20171264
database_cross_reference: ChemicalBookNo:CB0111892
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:3533602

boron trifluoride methanol
type: Class
subclass of: boron trifluoride reagent
definition: Boron trifluoride methanol.
has_exact_synonym: BF3-methanol
has_obo_namespace: XLMOD
id: XLMOD:09086

Axiom
annotated source: boron trifluoride methanol
annotated property: definition
annotated target: Boron trifluoride methanol.
database_cross_reference: CAS:373-57-9
database_cross_reference: ChemSpiderID:9237466
database_cross_reference: ChemicalBookNo:CB1184013
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:11062313

XLMOD_09088
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
has_exact_synonym: 2NFP-APB
has_obo_namespace: XLMOD
id: XLMOD:09088

Axiom
annotated source: XLMOD_09088
annotated property: definition
database_cross_reference: PMID:15897015

2-nitro-4-trifluoromethylphenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 2-nitro-4-trifluoromethylphenylhydrazine.
has_exact_synonym: 2-NFPH
has_exact_synonym: NFPH
has_obo_namespace: XLMOD
id: XLMOD:09089

Axiom
annotated source: 2-nitro-4-trifluoromethylphenylhydrazine
annotated property: definition
annotated target: 2-nitro-4-trifluoromethylphenylhydrazine.
database_cross_reference: CAS:1513-50-4
database_cross_reference: ChemSpiderID:3063768
database_cross_reference: ChemicalBookNo:CB5751590
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:3838097

4-chloro-7-nitro-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: halobenzofurazan
definition: 4-chloro-7-nitro-2,1,3-benzoxadiazole.
has_exact_synonym: 4-Chloro-7-nitrobenzofurazan
has_exact_synonym: NBDCl
has_obo_namespace: XLMOD
id: XLMOD:09090

Axiom
annotated source: 4-chloro-7-nitro-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-chloro-7-nitro-2,1,3-benzoxadiazole.
database_cross_reference: CAS:10199-89-0
database_cross_reference: ChemSpiderID:23406
database_cross_reference: ChemicalBookNo:CB5173637
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:25043

NBD-PZ Hydrochloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: halobenzofurazan
definition: NBD-PZ Hydrochloride.
has_exact_synonym: 4-Nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole hydrochloride
has_obo_namespace: XLMOD
id: XLMOD:09091

Axiom
annotated source: NBD-PZ Hydrochloride
annotated property: definition
annotated target: NBD-PZ Hydrochloride.
database_cross_reference: CAS:374730-75-3
database_cross_reference: ChemSpiderID:24746629
database_cross_reference: ChemicalBookNo:CB52558061
database_cross_reference: PMID:15897015
database_cross_reference: PubChem_Compound:71751110

sulfanilic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Sulfanilic acid.
has_exact_synonym: 4-aminobenzenesulphonic acid
has_obo_namespace: XLMOD
id: XLMOD:09092

Axiom
annotated source: sulfanilic acid
annotated property: definition
annotated target: Sulfanilic acid.
database_cross_reference: CAS:121-57-3
database_cross_reference: ChemSpiderID:8166
database_cross_reference: ChemicalBookNo:CB1489237
database_cross_reference: PMID:7756703
database_cross_reference: PubChem_Compound:8479

1-chloro-4-methylpyridinium iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 1-chloro-4-methylpyridinium iodide.
has_exact_synonym: CMPI
has_obo_namespace: XLMOD
id: XLMOD:09093

Axiom
annotated source: 1-chloro-4-methylpyridinium iodide
annotated property: definition
annotated target: 1-chloro-4-methylpyridinium iodide.
database_cross_reference: ChemSpiderID:29321698
database_cross_reference: PMID:12621624

3-(2,5-dioxopyrrolidin-1-yl-oxycarbonyl)propyl]trimethylammonium chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 3-(2,5-dioxopyrrolidin-1-yl-oxycarbonyl)propyl]trimethylammonium chloride.
has_exact_synonym: TMAB
has_obo_namespace: XLMOD
id: XLMOD:09094

Axiom
annotated source: 3-(2,5-dioxopyrrolidin-1-yl-oxycarbonyl)propyl]trimethylammonium chloride
annotated property: definition
annotated target: 3-(2,5-dioxopyrrolidin-1-yl-oxycarbonyl)propyl]trimethylammonium chloride.
database_cross_reference: PMID:22575224

N-methylnicotinic acid N-hydroxysuccinimide ester
type: Class
subclass of: NA-NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: N-methylnicotinic acid N-hydroxysuccinimide ester.
has_exact_synonym: C1-NA-NHS
has_obo_namespace: XLMOD
id: XLMOD:09095

Axiom
annotated source: N-methylnicotinic acid N-hydroxysuccinimide ester
annotated property: definition
annotated target: N-methylnicotinic acid N-hydroxysuccinimide ester.
database_cross_reference: PMID:21382752
database_cross_reference: PMID:23524938

deuterium labelled N-methylnicotinic acid N-hydroxysuccinimide ester
type: Class
subclass of: NA-NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Deuterium labelled N-methylnicotinic acid N-hydroxysuccinimide ester.
has_exact_synonym: C1-NA-NHS-d3
has_exact_synonym: C1D3-NA-NHS
has_obo_namespace: XLMOD
id: XLMOD:09096

Axiom
annotated source: deuterium labelled N-methylnicotinic acid N-hydroxysuccinimide ester
annotated property: definition
annotated target: Deuterium labelled N-methylnicotinic acid N-hydroxysuccinimide ester.
database_cross_reference: PMID:23524938
database_cross_reference: PMID:23628173

N-propylnicotinic acid N-hydroxysuccinimide ester
type: Class
subclass of: NA-NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: N-propylnicotinic acid N-hydroxysuccinimide ester.
has_exact_synonym: C3-NA-NHS
has_obo_namespace: XLMOD
id: XLMOD:09097

Axiom
annotated source: N-propylnicotinic acid N-hydroxysuccinimide ester
annotated property: definition
annotated target: N-propylnicotinic acid N-hydroxysuccinimide ester.
database_cross_reference: PMID:23524938

deuterium labelled N-propylnicotinic acid N-hydroxysuccinimide ester
type: Class
subclass of: NA-NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: Deuterium labelled N-propylnicotinic acid N-hydroxysuccinimide ester.
has_exact_synonym: C3-NA-NHS-d7
has_exact_synonym: C3D7-NA-NHS
has_obo_namespace: XLMOD
id: XLMOD:09098

Axiom
annotated source: deuterium labelled N-propylnicotinic acid N-hydroxysuccinimide ester
annotated property: definition
annotated target: Deuterium labelled N-propylnicotinic acid N-hydroxysuccinimide ester.
database_cross_reference: PMID:23524938

N-butylnicotinic acid N-hydroxysuccinimide ester
type: Class
subclass of: NA-NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: N-butylnicotinic acid N-hydroxysuccinimide ester.
has_exact_synonym: C4-NA-NHS
has_obo_namespace: XLMOD
id: XLMOD:09099

Axiom
annotated source: N-butylnicotinic acid N-hydroxysuccinimide ester
annotated property: definition
annotated target: N-butylnicotinic acid N-hydroxysuccinimide ester.
database_cross_reference: PMID:23524938

deuterium labelled N-butylnicotinic acid N-hydroxysuccinimide ester
type: Class
subclass of: NA-NHS ester
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: Deuterium labelled N-butylnicotinic acid N-hydroxysuccinimide ester.
has_exact_synonym: C4-NA-NHS-d9
has_exact_synonym: C4D9-NA-NHS
has_obo_namespace: XLMOD
id: XLMOD:09100

Axiom
annotated source: deuterium labelled N-butylnicotinic acid N-hydroxysuccinimide ester
annotated property: definition
annotated target: Deuterium labelled N-butylnicotinic acid N-hydroxysuccinimide ester.
database_cross_reference: PMID:23524938

2,4-Dinitrofluorobenzene
type: Class
subclass of: Sanger type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl halide
definition: 2,4-Dinitrofluorobenzene.
has_exact_synonym: 1-Fluoro-2,4-dinitrobenzene
has_exact_synonym: DNFB
has_exact_synonym: FNDB
has_obo_namespace: XLMOD
id: XLMOD:09101

Axiom
annotated source: 2,4-Dinitrofluorobenzene
annotated property: definition
annotated target: 2,4-Dinitrofluorobenzene.
database_cross_reference: CAS:70-34-8
database_cross_reference: ChemSpiderID:21106037
database_cross_reference: ChemicalBookNo:CB9442373
database_cross_reference: PMID:16808485
database_cross_reference: PubChem_Compound:6264

4-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: carabamate
definition: 4-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide.
has_exact_synonym: TAHS
has_exact_synonym: p-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide
has_obo_namespace: XLMOD
id: XLMOD:09102

Axiom
annotated source: 4-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide
annotated property: definition
annotated target: 4-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide.
database_cross_reference: PMID:22575224

deuterium labelled p-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: carabamate
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled p-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide.
has_exact_synonym: TAHS-d3
has_obo_namespace: XLMOD
id: XLMOD:09103

Axiom
annotated source: deuterium labelled p-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide
annotated property: definition
annotated target: Deuterium labelled p-N,N,N-trimethylammonioanilylN'-hydroxysuccinimidyl carbamate iodide.
database_cross_reference: PMID:22575224

4-methylpiperazine acetyl succinimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: 4-methylpiperazine acetyl succinimide.
has_exact_synonym: MPAS
has_obo_namespace: XLMOD
id: XLMOD:09104

Axiom
annotated source: 4-methylpiperazine acetyl succinimide
annotated property: definition
annotated target: 4-methylpiperazine acetyl succinimide.
database_cross_reference: PMID:22575224

deuterium labelled 4-methylpiperazine acetyl succinimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Deuterium labelled 4-methylpiperazine acetyl succinimide.
has_exact_synonym: MPAS-d3
has_obo_namespace: XLMOD
id: XLMOD:09105

Axiom
annotated source: deuterium labelled 4-methylpiperazine acetyl succinimide
annotated property: definition
annotated target: Deuterium labelled 4-methylpiperazine acetyl succinimide.
database_cross_reference: PMID:22575224

4-methylpiperadinebutyryl succinimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: 4-methylpiperadinebutyryl succinimide.
has_exact_synonym: MPBS
has_obo_namespace: XLMOD
id: XLMOD:09106

Axiom
annotated source: 4-methylpiperadinebutyryl succinimide
annotated property: definition
annotated target: 4-methylpiperadinebutyryl succinimide.
database_cross_reference: PMID:22575224

deuterium labelled 4-methylpiperadinebutyryl succinimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Deuterium labelled 4-methylpiperadinebutyryl succinimide.
has_exact_synonym: MPBS-d3
has_obo_namespace: XLMOD
id: XLMOD:09107

Axiom
annotated source: deuterium labelled 4-methylpiperadinebutyryl succinimide
annotated property: definition
annotated target: Deuterium labelled 4-methylpiperadinebutyryl succinimide.
database_cross_reference: PMID:22575224

dimethylaminobutyryl succinimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Dimethylaminobutyryl succinimide.
has_exact_synonym: DMABS
has_obo_namespace: XLMOD
id: XLMOD:09108

Axiom
annotated source: dimethylaminobutyryl succinimide
annotated property: definition
annotated target: Dimethylaminobutyryl succinimide.
database_cross_reference: PMID:22575224

deuterium labelled dimethylaminobutyryl succinimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Deuterium labelled dimethylaminobutyryl succinimide.
has_exact_synonym: DMABS-d3
has_obo_namespace: XLMOD
id: XLMOD:09109

Axiom
annotated source: deuterium labelled dimethylaminobutyryl succinimide
annotated property: definition
annotated target: Deuterium labelled dimethylaminobutyryl succinimide.
database_cross_reference: PMID:22575224

13C-dansyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: nucleoside reactive
definition: 13C-dansyl chloride.
has_exact_synonym: 13C DNS-Cl
has_obo_namespace: XLMOD
id: XLMOD:09110

Axiom
annotated source: 13C-dansyl chloride
annotated property: definition
annotated target: 13C-dansyl chloride.
database_cross_reference: PMID:22575224

pentafluorophenyl-activated ester of polyethyleneglycol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: pentafluorophenyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Pentafluorophenyl-activated ester of polyethyleneglycol.
has_exact_synonym: PEG-OPFP
has_obo_namespace: XLMOD
id: XLMOD:09111

Axiom
annotated source: pentafluorophenyl-activated ester of polyethyleneglycol
annotated property: definition
annotated target: Pentafluorophenyl-activated ester of polyethyleneglycol.
database_cross_reference: PMID:18954088

13C labelled pentafluorophenyl-activated ester of polyethyleneglycol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: pentafluorophenyl
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: 13C labelled pentafluorophenyl-activated ester of polyethyleneglycol.
has_exact_synonym: 13C-PEG-OPFP
has_obo_namespace: XLMOD
id: XLMOD:09112

Axiom
annotated source: 13C labelled pentafluorophenyl-activated ester of polyethyleneglycol
annotated property: definition
annotated target: 13C labelled pentafluorophenyl-activated ester of polyethyleneglycol.
database_cross_reference: PMID:18954088

cholamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Cholamine.
has_obo_namespace: XLMOD
id: XLMOD:09113

Axiom
annotated source: cholamine
annotated property: definition
annotated target: Cholamine.
database_cross_reference: ChemicalBookNo:CB8492922
database_cross_reference: PMID:22575224

deuterium labelled cholamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Deuterium labelled cholamine.
has_exact_synonym: cholamine-d9
has_obo_namespace: XLMOD
id: XLMOD:09114

Axiom
annotated source: deuterium labelled cholamine
annotated property: definition
annotated target: Deuterium labelled cholamine.
database_cross_reference: PMID:22575224

2-bromo-1-methylpyridinium iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 2-bromo-1-methylpyridinium iodide.
has_exact_synonym: BMP
has_obo_namespace: XLMOD
id: XLMOD:09115

Axiom
annotated source: 2-bromo-1-methylpyridinium iodide
annotated property: definition
annotated target: 2-bromo-1-methylpyridinium iodide.
database_cross_reference: CAS:52693-56-8
database_cross_reference: ChemSpiderID:11554184
database_cross_reference: ChemicalBookNo:CB13083603
database_cross_reference: PMID:22575224
database_cross_reference: PubChem_Compound:12233907

deuterium labelled 2-bromo-1-methylpyridinium iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Deuterium labelled 2-bromo-1-methylpyridinium iodide.
has_exact_synonym: BMP-d3
has_obo_namespace: XLMOD
id: XLMOD:09116

Axiom
annotated source: deuterium labelled 2-bromo-1-methylpyridinium iodide
annotated property: definition
annotated target: Deuterium labelled 2-bromo-1-methylpyridinium iodide.
database_cross_reference: PMID:22575224

3-carbinol-1-methylpyridinium iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-carbinol-1-methylpyridinium iodide.
has_exact_synonym: CMP
has_obo_namespace: XLMOD
id: XLMOD:09117

Axiom
annotated source: 3-carbinol-1-methylpyridinium iodide
annotated property: definition
annotated target: 3-carbinol-1-methylpyridinium iodide.
database_cross_reference: PMID:22575224

deuterium labelled 3-carbinol-1-methylpyridinium iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Deuterium labelled 3-carbinol-1-methylpyridinium iodide.
has_exact_synonym: CMP-d3
has_obo_namespace: XLMOD
id: XLMOD:09118

Axiom
annotated source: deuterium labelled 3-carbinol-1-methylpyridinium iodide
annotated property: definition
annotated target: Deuterium labelled 3-carbinol-1-methylpyridinium iodide.
database_cross_reference: PMID:22575224

4-dimethylaminophenacyl bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: phenacyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 4-dimethylaminophenacyl bromide.
has_exact_synonym: 2-Bromo-1-[4-(dimethylamino)phenyl]ethanone
has_exact_synonym: DmPA-Br
has_exact_synonym: p-dimethylaminophenacyl bromide
has_obo_namespace: XLMOD
id: XLMOD:09119

Axiom
annotated source: 4-dimethylaminophenacyl bromide
annotated property: definition
annotated target: 4-dimethylaminophenacyl bromide.
database_cross_reference: CAS:37904-72-6
database_cross_reference: ChemSpiderID:125460
database_cross_reference: ChemicalBookNo:CB4113692
database_cross_reference: PMID:22575224
database_cross_reference: PubChem_Compound:142225

13C labelled p-dimethylaminophenacyl bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: phenacyl
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 13C labelled p-dimethylaminophenacyl bromide.
has_exact_synonym: 13C-DmPA-Br
has_obo_namespace: XLMOD
id: XLMOD:09120

Axiom
annotated source: 13C labelled p-dimethylaminophenacyl bromide
annotated property: definition
annotated target: 13C labelled p-dimethylaminophenacyl bromide.
database_cross_reference: PMID:22575224

7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole.
has_exact_synonym: DBD-PZ-NH2
has_obo_namespace: XLMOD
id: XLMOD:09121

Axiom
annotated source: 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole
annotated property: definition
annotated target: 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole.
database_cross_reference: PMID:22575224

deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole.
has_exact_synonym: DBD-PZ-NH2-d6
has_obo_namespace: XLMOD
id: XLMOD:09122

Axiom
annotated source: deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole
annotated property: definition
annotated target: Deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-(aminoethyl)piperadino-2,1-3-benzoxadiazole.
database_cross_reference: PMID:16167303
database_cross_reference: PMID:22575224

7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole.
has_exact_synonym: 4-(N,N-dimethylaminosulfonyl)-7-(1-piperazinyl)-2,1,3-benzoxadiazole
has_exact_synonym: DBD-PZ
has_obo_namespace: XLMOD
id: XLMOD:09123

Axiom
annotated source: 7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole
annotated property: definition
annotated target: 7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole.
database_cross_reference: PMID:22575224

deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole.
has_exact_synonym: DBD-PZ-d6
has_obo_namespace: XLMOD
id: XLMOD:09124

Axiom
annotated source: deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole
annotated property: definition
annotated target: Deuterium labelled 7-(N,N-dimethylaminosulfonyl)-4-piperadino-2,1-3-benzoxadiazole.
database_cross_reference: PMID:22575224

deuterium labelled Girard's reagent P
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Deuterium labelled pyridinioacetohydrazide chloride.
has_exact_synonym: GP-d5
has_exact_synonym: Gir P-d5
has_obo_namespace: XLMOD
id: XLMOD:09125

Axiom
annotated source: deuterium labelled Girard's reagent P
annotated property: definition
annotated target: Deuterium labelled pyridinioacetohydrazide chloride.
database_cross_reference: PMID:22575224

deuterium labelled 2,4-dinitrophenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 2,4-dinitrophenyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: Deuterium labelled 2,4-dinitrophenylhydrazine.
has_exact_synonym: 2,4-Dinitro-3,5,6-trideuterophenylhydrazine
has_exact_synonym: DNPH-d3
has_obo_namespace: XLMOD
id: XLMOD:09126

Axiom
annotated source: deuterium labelled 2,4-dinitrophenylhydrazine
annotated property: definition
annotated target: Deuterium labelled 2,4-dinitrophenylhydrazine.
database_cross_reference: PMID:22575224

2-Phenylenediamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 2-Phenylenediamine.
has_exact_synonym: o-Phenylenediamine
has_obo_namespace: XLMOD
id: XLMOD:09127

Axiom
annotated source: 2-Phenylenediamine
annotated property: definition
annotated target: 2-Phenylenediamine.
database_cross_reference: CAS:95-54-5
database_cross_reference: ChemSpiderID:13837582
database_cross_reference: ChemicalBookNo:CB9854699
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:7243

5,5'-Dithio-(bis-2-nitrobenzoic) acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 5,5'-Dithio-(bis-2-nitrobenzoic) acid.
has_exact_synonym: Ellman's reagent
has_obo_namespace: XLMOD
id: XLMOD:09129

Axiom
annotated source: 5,5'-Dithio-(bis-2-nitrobenzoic) acid
annotated property: definition
annotated target: 5,5'-Dithio-(bis-2-nitrobenzoic) acid.
database_cross_reference: CAS:69-78-3
database_cross_reference: ChemSpiderID:6018
database_cross_reference: ChemicalBookNo:CB2215444
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:6254

4-(Hydroxymercuri)benzoate acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 4-(Hydroxymercuri)benzoate acid.
has_exact_synonym: p-(Hydroxymercuri)benzoate acid
has_obo_namespace: XLMOD
id: XLMOD:09130

Axiom
annotated source: 4-(Hydroxymercuri)benzoate acid
annotated property: definition
annotated target: 4-(Hydroxymercuri)benzoate acid.
database_cross_reference: CAS:138-85-2
database_cross_reference: ChemSpiderID:8104477
database_cross_reference: ChemicalBookNo:CB9350409
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:23667696

N-Ethylmaleimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-Ethylmaleimide.
has_exact_synonym: NEM
has_obo_namespace: XLMOD
id: XLMOD:09131

Axiom
annotated source: N-Ethylmaleimide
annotated property: definition
annotated target: N-Ethylmaleimide.
database_cross_reference: CAS:128-53-0
database_cross_reference: ChemSpiderID:4209
database_cross_reference: ChemicalBookNo:CB5748314
database_cross_reference: PMID:21382752
database_cross_reference: PMID:29906677
database_cross_reference: PubChem_Compound:4362

4-Methylbenzenesulfonyl isocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isocyanate
definition: 4-Methylbenzenesulfonyl isocyanate.
has_exact_synonym: Tosyl isocyanate
has_exact_synonym: p-Toluenesulfonyl isocyanate
has_obo_namespace: XLMOD
id: XLMOD:09132

Axiom
annotated source: 4-Methylbenzenesulfonyl isocyanate
annotated property: definition
annotated target: 4-Methylbenzenesulfonyl isocyanate.
database_cross_reference: CAS:4083-64-1
database_cross_reference: ChemSpiderID:70104
database_cross_reference: ChemicalBookNo:CB8256995
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:77703

1-(4-lsopropyl) phenyl-3-methyl-5-pyrazolone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: 1-(4-lsopropyl) phenyl-3-methyl-5-pyrazolone.
has_exact_synonym: PMPP
has_obo_namespace: XLMOD
id: XLMOD:09133

Axiom
annotated source: 1-(4-lsopropyl) phenyl-3-methyl-5-pyrazolone
annotated property: definition
annotated target: 1-(4-lsopropyl) phenyl-3-methyl-5-pyrazolone.
database_cross_reference: PMID:21382752

2-Sulfobenzoic anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
definition: 2-Sulfobenzoic anhydride.
has_obo_namespace: XLMOD
id: XLMOD:09134

Axiom
annotated source: 2-Sulfobenzoic anhydride
annotated property: definition
annotated target: 2-Sulfobenzoic anhydride.
database_cross_reference: CAS:81-08-3
database_cross_reference: ChemSpiderID:59152
database_cross_reference: ChemicalBookNo:CB4286815
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:65729

1-pyrenesulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
definition: 1-pyrenesulfonyl chloride.
has_exact_synonym: PSC
has_exact_synonym: Pyrene-1-sulfonyl chloride
has_obo_namespace: XLMOD
id: XLMOD:09135

Axiom
annotated source: 1-pyrenesulfonyl chloride
annotated property: definition
annotated target: 1-pyrenesulfonyl chloride.
database_cross_reference: CAS:61494-52-8
database_cross_reference: ChemSpiderID:2043373
database_cross_reference: ChemicalBookNo:CB0708281
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:2762670

2,3-Naphthalenedialdehyde
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 2,3-Naphthalenedialdehyde.
has_exact_synonym: Naphthalene-2,3-dicarbaldehyde
has_obo_namespace: XLMOD
id: XLMOD:09136

Axiom
annotated source: 2,3-Naphthalenedialdehyde
annotated property: definition
annotated target: 2,3-Naphthalenedialdehyde.
database_cross_reference: CAS:7149-49-7
database_cross_reference: ChemSpiderID:87023
database_cross_reference: ChemicalBookNo:CB5283316
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:96400

3-chlorocarbonyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 3-chlorocarbonyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone.
has_exact_synonym: DMEQ-COCI
has_obo_namespace: XLMOD
id: XLMOD:09137

Axiom
annotated source: 3-chlorocarbonyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone
annotated property: definition
annotated target: 3-chlorocarbonyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone.
database_cross_reference: CAS:104077-15-8
database_cross_reference: ChemSpiderID:129681
database_cross_reference: ChemicalBookNo:CB6511517
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:147056

Fluorescein-5-isothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: Fluorescein-5-isothiocyanate.
has_obo_namespace: XLMOD
id: XLMOD:09138

Axiom
annotated source: Fluorescein-5-isothiocyanate
annotated property: definition
annotated target: Fluorescein-5-isothiocyanate.
database_cross_reference: CAS:3326-32-7
database_cross_reference: ChemSpiderID:17686
database_cross_reference: ChemicalBookNo:CB0173162
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:18730

2-Chloro-1-methylpyridinium
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 2-Chloro-1-methylpyridinium.
has_obo_namespace: XLMOD
id: XLMOD:09139

Axiom
annotated source: 2-Chloro-1-methylpyridinium
annotated property: definition
annotated target: 2-Chloro-1-methylpyridinium.
database_cross_reference: CAS:45528-84-5
database_cross_reference: ChemSpiderID:146180
database_cross_reference: ChemicalBookNo:CB11376592
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:167070

(5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: (5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide.
has_obo_namespace: XLMOD
id: XLMOD:09140

Axiom
annotated source: (5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide
annotated property: definition
annotated target: (5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide.
database_cross_reference: PMID:21382752

Diethylethoxymethylenemalonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Diethylethoxymethylenemalonate.
has_exact_synonym: DEEMM
has_obo_namespace: XLMOD
id: XLMOD:09141

Axiom
annotated source: Diethylethoxymethylenemalonate
annotated property: definition
annotated target: Diethylethoxymethylenemalonate.
database_cross_reference: CAS:87-13-8
database_cross_reference: ChemSpiderID:6609
database_cross_reference: ChemicalBookNo:CB3163908
database_cross_reference: PMID:21382752
database_cross_reference: PMID:22889992
database_cross_reference: PubChem_Compound:6871

4-(dimethylamino)phenyl isothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: 4-(dimethylamino)phenyl isothiocyanate.
has_exact_synonym: DMAP-NCS
has_exact_synonym: p-Dimethylaminophenyl isothiocyanate
has_exact_synonym: p-Isothiocyanato-N,N-dimethylaniline
has_obo_namespace: XLMOD
id: XLMOD:09142

Axiom
annotated source: 4-(dimethylamino)phenyl isothiocyanate
annotated property: definition
annotated target: 4-(dimethylamino)phenyl isothiocyanate.
database_cross_reference: CAS:2131-64-8
database_cross_reference: ChemSpiderID:67599
database_cross_reference: ChemicalBookNo:CB6742874
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:75047

3-Nitrophenyl isothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: 3-Nitrophenyl isothiocyanate.
has_exact_synonym: m-Nitrophenyl isothiocyanate
has_obo_namespace: XLMOD
id: XLMOD:09143

Axiom
annotated source: 3-Nitrophenyl isothiocyanate
annotated property: definition
annotated target: 3-Nitrophenyl isothiocyanate.
database_cross_reference: CAS:3529-82-6
database_cross_reference: ChemSpiderID:17985
database_cross_reference: ChemicalBookNo:CB5235618
database_cross_reference: PMID:21382752
database_cross_reference: PubChem_Compound:19050

3-aminopyridyl-N-hydroxysuccinimidylcarbamate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: carabamate
definition: 3-aminopyridyl-N-hydroxysuccinimidylcarbamate.
has_exact_synonym: APDS
has_obo_namespace: XLMOD
id: XLMOD:09144

Axiom
annotated source: 3-aminopyridyl-N-hydroxysuccinimidylcarbamate
annotated property: definition
annotated target: 3-aminopyridyl-N-hydroxysuccinimidylcarbamate.
database_cross_reference: PMID:21382752

N-(4-aminomethylphenyl)pyridinium
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: N-(4-aminomethylphenyl)pyridinium.
has_exact_synonym: AMPP
has_obo_namespace: XLMOD
id: XLMOD:09145

Axiom
annotated source: N-(4-aminomethylphenyl)pyridinium
annotated property: definition
annotated target: N-(4-aminomethylphenyl)pyridinium.
database_cross_reference: PMID:21382752

Cyclohexanedione
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: Cyclohexanedione.
has_exact_synonym: CHD
has_obo_namespace: XLMOD
id: XLMOD:09146

Axiom
annotated source: Cyclohexanedione
annotated property: definition
annotated target: Cyclohexanedione.
database_cross_reference: CAS:765-87-7
database_cross_reference: ChemSpiderID:12465
database_cross_reference: ChemicalBookNo:CB7854271
database_cross_reference: PMID:26496130
database_cross_reference: PubChem_Compound:13006

2-fluoro-1-methylpyridium
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: hydroxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: phenol reactive
definition: 2-fluoro-1-methylpyridium.
has_exact_synonym: 2-FMP
has_obo_namespace: XLMOD
id: XLMOD:09148

Axiom
annotated source: 2-fluoro-1-methylpyridium
annotated property: definition
annotated target: 2-fluoro-1-methylpyridium.
database_cross_reference: PMID:26454158
database_cross_reference: PMID:26496130

triplex 5-diethylaminonaphthalene-1-sulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
definition: Triplex 5-diethylaminonaphthalene-1-sulfonyl chloride.
has_exact_synonym: DensCl
has_obo_namespace: XLMOD
id: XLMOD:09149

Axiom
annotated source: triplex 5-diethylaminonaphthalene-1-sulfonyl chloride
annotated property: definition
annotated target: Triplex 5-diethylaminonaphthalene-1-sulfonyl chloride.
database_cross_reference: PMID:26496130

N-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide
type: Class
subclass of: chiral derivatization reagent
subclass of: Marfey type reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 2,4-dinitrophenyl
definition: N-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide.
has_exact_synonym: D-FDLA
has_obo_namespace: XLMOD
id: XLMOD:09150

Axiom
annotated source: N-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide
annotated property: definition
annotated target: N-(5-fluoro-2,4-dinitrophenyl)-D-leucinamide.
database_cross_reference: PMID:26496130

ebselen
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: Ebselen.
has_obo_namespace: XLMOD
id: XLMOD:09152

Axiom
annotated source: ebselen
annotated property: definition
annotated target: Ebselen.
database_cross_reference: CAS:60940-34-3
database_cross_reference: ChemSpiderID:3082
database_cross_reference: ChemicalBookNo:CB5301009
database_cross_reference: PMID:26496130
database_cross_reference: PubChem_Compound:3194

iodoacetamide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: Iodoacetamide.
has_exact_synonym: IAM
has_obo_namespace: XLMOD
id: XLMOD:09153

Axiom
annotated source: iodoacetamide
annotated property: definition
annotated target: Iodoacetamide.
database_cross_reference: CAS:144-48-9
database_cross_reference: ChemSpiderID:3596
database_cross_reference: ChemicalBookNo:CB4760867
database_cross_reference: PMID:26496130
database_cross_reference: PubChem_Compound:3727

isopropylchloroformate
type: Class
subclass of: chloroformate reagent
definition: Isopropylchloroformate.
has_exact_synonym: IPCF
has_obo_namespace: XLMOD
id: XLMOD:09154

Axiom
annotated source: isopropylchloroformate
annotated property: definition
annotated target: Isopropylchloroformate.
database_cross_reference: CAS:108-23-6
database_cross_reference: ChemSpiderID:7629
database_cross_reference: ChemicalBookNo:CB5702693
database_cross_reference: PMID:26496130
database_cross_reference: PubChem_Compound:7917

2-Nitrobenzaldehyde
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 2-Nitrobenzaldehyde.
has_exact_synonym: 2-NB
has_obo_namespace: XLMOD
id: XLMOD:09155

Axiom
annotated source: 2-Nitrobenzaldehyde
annotated property: definition
annotated target: 2-Nitrobenzaldehyde.
database_cross_reference: CAS:552-89-6
database_cross_reference: ChemSpiderID:10630
database_cross_reference: ChemicalBookNo:CB8414184
database_cross_reference: PMID:26496130
database_cross_reference: PubChem_Compound:11101

5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide.
has_exact_synonym: SPTPP
has_obo_namespace: XLMOD
id: XLMOD:09157

Axiom
annotated source: 5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide
annotated property: definition
annotated target: 5-N-succinimidoxy-5-oxopentyl)triphenylphosphonium bromide.
database_cross_reference: PMID:22889992

2,5-dioxopyrrolidin-1-yl N-tri(pyrrolidino)phosphoranylideneamino carbamate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: carabamate
definition: 2,5-dioxopyrrolidin-1-yl N-tri(pyrrolidino)phosphoranylideneamino carbamate.
has_exact_synonym: FOSF
has_obo_namespace: XLMOD
id: XLMOD:09158

Axiom
annotated source: 2,5-dioxopyrrolidin-1-yl N-tri(pyrrolidino)phosphoranylideneamino carbamate
annotated property: definition
annotated target: 2,5-dioxopyrrolidin-1-yl N-tri(pyrrolidino)phosphoranylideneamino carbamate.
database_cross_reference: PMID:22889992

2-nitrophenylhydrazine hydrochloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 2-nitrophenylhydrazine hydrochloride.
has_exact_synonym: 2-NPH-HCl
has_obo_namespace: XLMOD
id: XLMOD:09159

Axiom
annotated source: 2-nitrophenylhydrazine hydrochloride
annotated property: definition
annotated target: 2-nitrophenylhydrazine hydrochloride.
database_cross_reference: CAS:56413-75-3
database_cross_reference: ChemSpiderID:21306
database_cross_reference: ChemicalBookNo:CB5875432
database_cross_reference: PMID:10905720
database_cross_reference: PMID:3429573
database_cross_reference: PubChem_Compound:5743520

phenacyl bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: phenacyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Phenacyl bromide.
has_exact_synonym: 2-Bromoacetophenone
has_obo_namespace: XLMOD
id: XLMOD:09161

Axiom
annotated source: phenacyl bromide
annotated property: definition
annotated target: Phenacyl bromide.
database_cross_reference: CAS:70-11-1
database_cross_reference: ChemSpiderID:6023
database_cross_reference: ChemicalBookNo:CB6305185
database_cross_reference: PMID:3394930
database_cross_reference: PubChem_Compound:6259

2-(4-nitro-benzyl)-N,N'-diisopropyl-iso-urea
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 2-(4-nitro-benzyl)-N,N'-diisopropyl-iso-urea.
has_exact_synonym: o-(4-nitro-benzyl)-N,N'-diisopropyl-iso-urea
has_obo_namespace: XLMOD
id: XLMOD:09163

Axiom
annotated source: 2-(4-nitro-benzyl)-N,N'-diisopropyl-iso-urea
annotated property: definition
annotated target: 2-(4-nitro-benzyl)-N,N'-diisopropyl-iso-urea.
database_cross_reference: PMID:3394930

3-nitrophenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 3-nitrophenylhydrazine.
has_exact_synonym: 3-NPH
has_obo_namespace: XLMOD
id: XLMOD:09164

Axiom
annotated source: 3-nitrophenylhydrazine
annotated property: definition
annotated target: 3-nitrophenylhydrazine.
database_cross_reference: PMID:23580203

butyl 1-(pyridin-4-yl) piperidine 4-carboxylate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: Butyl 1-(pyridin-4-yl) piperidine 4-carboxylate.
has_exact_synonym: BPPC
has_obo_namespace: XLMOD
id: XLMOD:09165

Axiom
annotated source: butyl 1-(pyridin-4-yl) piperidine 4-carboxylate
annotated property: definition
annotated target: Butyl 1-(pyridin-4-yl) piperidine 4-carboxylate.
database_cross_reference: PMID:23245244

4-bromo-N-methylbenzylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: 4-bromo-N-methylbenzylamine.
has_exact_synonym: 4-BNMA
has_obo_namespace: XLMOD
id: XLMOD:09166

Axiom
annotated source: 4-bromo-N-methylbenzylamine
annotated property: definition
annotated target: 4-bromo-N-methylbenzylamine.
database_cross_reference: CAS:699-03-6
database_cross_reference: ChemSpiderID:425634
database_cross_reference: ChemicalBookNo:CB3478655
database_cross_reference: PMID:29213145
database_cross_reference: PubChem_Compound:485400

N-methyl-2-phenylethanamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: N-methyl-2-phenylethanamine.
has_exact_synonym: MPEA
has_obo_namespace: XLMOD
id: XLMOD:09167

Axiom
annotated source: N-methyl-2-phenylethanamine
annotated property: definition
annotated target: N-methyl-2-phenylethanamine.
database_cross_reference: CAS:589-08-2
database_cross_reference: ChemSpiderID:11019
database_cross_reference: ChemicalBookNo:CB6140245
database_cross_reference: PMID:29213145
database_cross_reference: PubChem_Compound:11503

benzoyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: acyl chloride
definition: Benzoyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:09168

Axiom
annotated source: benzoyl chloride
annotated property: definition
annotated target: Benzoyl chloride.
database_cross_reference: CAS:98-88-4
database_cross_reference: ChemSpiderID:7134
database_cross_reference: ChemicalBookNo:CB8854753
database_cross_reference: PMID:28660399
database_cross_reference: PubChem_Compound:7412

N-tert-butylmaleimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-tert-butylmaleimide.
has_exact_synonym: NrBM
has_obo_namespace: XLMOD
id: XLMOD:09169

Axiom
annotated source: N-tert-butylmaleimide
annotated property: definition
annotated target: N-tert-butylmaleimide.
database_cross_reference: CAS:4144-22-3
database_cross_reference: ChemSpiderID:558357
database_cross_reference: ChemicalBookNo:CB4720254
database_cross_reference: PMID:29906677
database_cross_reference: PubChem_Compound:643190

N-propylmaleimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-propylmaleimide.
has_exact_synonym: 1-Propylpyrrole-2,5-dione
has_exact_synonym: NPM
has_obo_namespace: XLMOD
id: XLMOD:09170

Axiom
annotated source: N-propylmaleimide
annotated property: definition
annotated target: N-propylmaleimide.
database_cross_reference: CAS:21746-40-7
database_cross_reference: ChemSpiderID:80338
database_cross_reference: ChemicalBookNo:CB9737837
database_cross_reference: PMID:29906677
database_cross_reference: PubChem_Compound:89033

4-hydrazinobenzoic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 4-hydrazinobenzoic acid.
has_exact_synonym: HBA
has_obo_namespace: XLMOD
id: XLMOD:09171

Axiom
annotated source: 4-hydrazinobenzoic acid
annotated property: definition
annotated target: 4-hydrazinobenzoic acid.
database_cross_reference: CAS:619-67-0
database_cross_reference: ChemSpiderID:11592
database_cross_reference: ChemicalBookNo:CB5271632
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:12089

2-aminoethanethiol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 2-aminoethanethiol.
has_exact_synonym: Cysteamine
has_obo_namespace: XLMOD
id: XLMOD:09172

Axiom
annotated source: 2-aminoethanethiol
annotated property: definition
annotated target: 2-aminoethanethiol.
database_cross_reference: CAS:60-23-1
database_cross_reference: ChemSpiderID:5834
database_cross_reference: ChemicalBookNo:CB2223766
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:6058

2-diphenylacetyl-1,3-indandione-1-hydrazone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 2-diphenylacetyl-1,3-indandione-1-hydrazone.
has_exact_synonym: DAIH
has_obo_namespace: XLMOD
id: XLMOD:09173

Axiom
annotated source: 2-diphenylacetyl-1,3-indandione-1-hydrazone
annotated property: definition
annotated target: 2-diphenylacetyl-1,3-indandione-1-hydrazone.
database_cross_reference: CAS:5102-79-4
database_cross_reference: ChemicalBookNo:CB4455145
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:5375071

3-methylbenzothiazolin-2-one hydrazone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 3-methylbenzothiazolin-2-one hydrazone.
has_exact_synonym: (3-Methyl-1,3-benzothiazol-2-ylidene)hydrazine
has_exact_synonym: MBTH
has_obo_namespace: XLMOD
id: XLMOD:09174

Axiom
annotated source: 3-methylbenzothiazolin-2-one hydrazone
annotated property: definition
annotated target: 3-methylbenzothiazolin-2-one hydrazone.
database_cross_reference: CAS:1128-67-2
database_cross_reference: ChemSpiderID:4700314
database_cross_reference: ChemicalBookNo:CB2663986
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:5359575

cyclohexane-1,3-dione
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: Cyclohexane-1,3-dione.
has_exact_synonym: 1,3-Cyclohexanedione
has_exact_synonym: Dihydroresorcinol
has_obo_namespace: XLMOD
id: XLMOD:09175

Axiom
annotated source: cyclohexane-1,3-dione
annotated property: definition
annotated target: Cyclohexane-1,3-dione.
database_cross_reference: CAS:504-02-9
database_cross_reference: ChemSpiderID:10004
database_cross_reference: ChemicalBookNo:CB8319650
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:10434

pyroglutamic acid succinimidyl ester
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Pyroglutamic acid succinimidyl ester.
has_exact_synonym: PGA-OSu
has_obo_namespace: XLMOD
id: XLMOD:09176

Axiom
annotated source: pyroglutamic acid succinimidyl ester
annotated property: definition
annotated target: Pyroglutamic acid succinimidyl ester.
database_cross_reference: PMID:27582321

2,4,6-trichlorophenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 2,4,6-trichlorophenylhydrazine.
has_exact_synonym: 2,4,6-Trichlorophenylhydrazine
has_obo_namespace: XLMOD
id: XLMOD:09177

Axiom
annotated source: 2,4,6-trichlorophenylhydrazine
annotated property: definition
annotated target: 2,4,6-trichlorophenylhydrazine.
database_cross_reference: CAS:5329-12-4
database_cross_reference: ChemSpiderID:71559
database_cross_reference: ChemicalBookNo:CB4690892
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:79234

O-2,3,4,5,6-(pentafluorobenzyl) hydroxylamine hydrochloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: O-2,3,4,5,6-(pentafluorobenzyl) hydroxylamine hydrochloride.
has_exact_synonym: Florox Reagent
has_exact_synonym: PFBO
has_obo_namespace: XLMOD
id: XLMOD:09178

Axiom
annotated source: O-2,3,4,5,6-(pentafluorobenzyl) hydroxylamine hydrochloride
annotated property: definition
annotated target: O-2,3,4,5,6-(pentafluorobenzyl) hydroxylamine hydrochloride.
database_cross_reference: CAS:57981-02-9
database_cross_reference: ChemSpiderID:109062
database_cross_reference: ChemicalBookNo:CB8307815
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:122307

benzoyl hydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: Benzoyl hydrazine.
has_obo_namespace: XLMOD
id: XLMOD:09179

Axiom
annotated source: benzoyl hydrazine
annotated property: definition
annotated target: Benzoyl hydrazine.
database_cross_reference: CAS:613-94-5
database_cross_reference: ChemSpiderID:11461
database_cross_reference: ChemicalBookNo:CB2760863
database_cross_reference: PMID:29853022
database_cross_reference: PubChem_Compound:11955

2-Iodoacetanilide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 2-Iodoacetanilide.
has_exact_synonym: 2-IAN
has_obo_namespace: XLMOD
id: XLMOD:09180

Axiom
annotated source: 2-Iodoacetanilide
annotated property: definition
annotated target: 2-Iodoacetanilide.
database_cross_reference: CAS:19591-17-4
database_cross_reference: ChemSpiderID:123972
database_cross_reference: ChemicalBookNo:CB2169857
database_cross_reference: PMID:29650481
database_cross_reference: PubChem_Compound:140559

N-hydroxy-benzotriazolyl-(S)-naproxen ester
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: histamine reactive
definition: N-hydroxy-benzotriazolyl-(S)-naproxen ester.
has_exact_synonym: Npx-ester
has_obo_namespace: XLMOD
id: XLMOD:09181

Axiom
annotated source: N-hydroxy-benzotriazolyl-(S)-naproxen ester
annotated property: definition
annotated target: N-hydroxy-benzotriazolyl-(S)-naproxen ester.
database_cross_reference: PMID:29601646

methyl acetimidate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Methyl acetimidate.
has_obo_namespace: XLMOD
id: XLMOD:09182

Axiom
annotated source: methyl acetimidate
annotated property: definition
annotated target: Methyl acetimidate.
database_cross_reference: CAS:14777-29-8
database_cross_reference: ChemSpiderID:10652948
database_cross_reference: ChemicalBookNo:CB1506534
database_cross_reference: PMID:23628173
database_cross_reference: PubChem_Compound:26888

13C labelled methyl acetimidate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 13C labelled methyl acetimidate.
has_exact_synonym: 13C-methyl acetimidate
has_obo_namespace: XLMOD
id: XLMOD:09183

Axiom
annotated source: 13C labelled methyl acetimidate
annotated property: definition
annotated target: 13C labelled methyl acetimidate.
database_cross_reference: PMID:23628173

13C labelled formaldehyde
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: aldehyde group
subclass of: Restriction
  on property: is_labelled
  some values from: 13C labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 13C labelled formaldehyde reagent.
has_exact_synonym: 13C-formaldehyde
has_obo_namespace: XLMOD
id: XLMOD:09184

Axiom
annotated source: 13C labelled formaldehyde
annotated property: definition
annotated target: 13C labelled formaldehyde reagent.
database_cross_reference: PMID:23628173

acetaldehyde
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Acetaldehyde.
has_obo_namespace: XLMOD
id: XLMOD:09185

Axiom
annotated source: acetaldehyde
annotated property: definition
annotated target: Acetaldehyde.
database_cross_reference: CAS:75-07-0
database_cross_reference: ChemSpiderID:172
database_cross_reference: ChemicalBookNo:CB8175809
database_cross_reference: PMID:23628173
database_cross_reference: PubChem_Compound:177

deuterium labelled acetaldehyde
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Deuterium labelled acetaldehyde.
has_exact_synonym: acetaldehyde-d4
has_obo_namespace: XLMOD
id: XLMOD:09186

Axiom
annotated source: deuterium labelled acetaldehyde
annotated property: definition
annotated target: Deuterium labelled acetaldehyde.
database_cross_reference: PMID:23628173

4-(4-methyl-1-piperazyl)-3-nitrobenzoyl azide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 4-(4-methyl-1-piperazyl)-3-nitrobenzoyl azide.
has_exact_synonym: APZ
has_obo_namespace: XLMOD
id: XLMOD:09187

Axiom
annotated source: 4-(4-methyl-1-piperazyl)-3-nitrobenzoyl azide
annotated property: definition
annotated target: 4-(4-methyl-1-piperazyl)-3-nitrobenzoyl azide.
database_cross_reference: PMID:23628173

dibenzyl ethoxymethylene malonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Dibenzyl ethoxymethylene malonate.
has_exact_synonym: DBEMM
has_obo_namespace: XLMOD
id: XLMOD:09188

Axiom
annotated source: dibenzyl ethoxymethylene malonate
annotated property: definition
annotated target: Dibenzyl ethoxymethylene malonate.
database_cross_reference: ChemSpiderID:48244742
database_cross_reference: PMID:26477276

benzyl ethyl ethoxymethylene malonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Benzyl ethyl ethoxymethylene malonate.
has_exact_synonym: EBEMM
has_obo_namespace: XLMOD
id: XLMOD:09189

Axiom
annotated source: benzyl ethyl ethoxymethylene malonate
annotated property: definition
annotated target: Benzyl ethyl ethoxymethylene malonate.
database_cross_reference: PMID:26477276

diisopropyl hydrogen phosphite
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: Diisopropyl hydrogen phosphite.
has_obo_namespace: XLMOD
id: XLMOD:09190

Axiom
annotated source: diisopropyl hydrogen phosphite
annotated property: definition
annotated target: Diisopropyl hydrogen phosphite.
database_cross_reference: CAS:1809-20-7
database_cross_reference: ChemSpiderID:485223
database_cross_reference: ChemicalBookNo:CB5671052
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:558181

2-(2-[7H-dibenzo (a,g)carbazol-7-yl]-ethoxy)ethyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: 2-(2-[7H-dibenzo (a,g)carbazol-7-yl]-ethoxy)ethyl chloroformate.
has_exact_synonym: DBCEC
has_obo_namespace: XLMOD
id: XLMOD:09191

Axiom
annotated source: 2-(2-[7H-dibenzo (a,g)carbazol-7-yl]-ethoxy)ethyl chloroformate
annotated property: definition
annotated target: 2-(2-[7H-dibenzo (a,g)carbazol-7-yl]-ethoxy)ethyl chloroformate.
database_cross_reference: PMID:26477276

ethyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: Ethyl chloroformate.
has_exact_synonym: ECF
has_obo_namespace: XLMOD
id: XLMOD:09192

Axiom
annotated source: ethyl chloroformate
annotated property: definition
annotated target: Ethyl chloroformate.
database_cross_reference: CAS:541-41-3
database_cross_reference: ChemSpiderID:10465
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:10928

1-bromobutane
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 1-bromobutane.
has_obo_namespace: XLMOD
id: XLMOD:09193

Axiom
annotated source: 1-bromobutane
annotated property: definition
annotated target: 1-bromobutane.
database_cross_reference: CAS:109-65-9
database_cross_reference: ChemSpiderID:7711
database_cross_reference: ChemicalBookNo:CB2852782
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:8002

2-bromopyridine-5-boronic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: boronic acid
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 2-bromopyridine-5-boronic acid.
has_exact_synonym: BPBA
has_obo_namespace: XLMOD
id: XLMOD:09194

Axiom
annotated source: 2-bromopyridine-5-boronic acid
annotated property: definition
annotated target: 2-bromopyridine-5-boronic acid.
database_cross_reference: CAS:223463-14-7
database_cross_reference: ChemSpiderID:2043406
database_cross_reference: ChemicalBookNo:CB4371649
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:2762706

(3-dimethylaminophenyl)dihydroxyborane
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: (3-dimethylaminophenyl)dihydroxyborane.
has_exact_synonym: DAPB
has_obo_namespace: XLMOD
id: XLMOD:09195

Axiom
annotated source: (3-dimethylaminophenyl)dihydroxyborane
annotated property: definition
annotated target: (3-dimethylaminophenyl)dihydroxyborane.
database_cross_reference: CAS:178752-79-9
database_cross_reference: ChemSpiderID:2043244
database_cross_reference: ChemicalBookNo:CB1220410
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:2762527

1-methylimidazole-2-sulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 1-methylimidazole-2-sulfonyl chloride.
has_exact_synonym: MLDS
has_obo_namespace: XLMOD
id: XLMOD:09196

Axiom
annotated source: 1-methylimidazole-2-sulfonyl chloride
annotated property: definition
annotated target: 1-methylimidazole-2-sulfonyl chloride.
database_cross_reference: CAS:55694-81-0
database_cross_reference: ChemSpiderID:9833118
database_cross_reference: ChemicalBookNo:CB22592929
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:11658383

N-methyl pyridinium-3-sulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: N-methyl pyridinium-3-sulfonyl chloride.
has_exact_synonym: NMPS
has_obo_namespace: XLMOD
id: XLMOD:09198

Axiom
annotated source: N-methyl pyridinium-3-sulfonyl chloride
annotated property: definition
annotated target: N-methyl pyridinium-3-sulfonyl chloride.
database_cross_reference: PMID:26477276

quaternary aminooxy reagent
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Quaternary aminooxy reagent.
has_exact_synonym: QAO
has_obo_namespace: XLMOD
id: XLMOD:09199

Axiom
annotated source: quaternary aminooxy reagent
annotated property: definition
annotated target: Quaternary aminooxy reagent.
database_cross_reference: PMID:26477276

2,4-dimethoxy-6-piperazin-1-yl pyrimidine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 2,4-dimethoxy-6-piperazin-1-yl pyrimidine.
has_exact_synonym: DMPP
has_obo_namespace: XLMOD
id: XLMOD:09200

Axiom
annotated source: 2,4-dimethoxy-6-piperazin-1-yl pyrimidine
annotated property: definition
annotated target: 2,4-dimethoxy-6-piperazin-1-yl pyrimidine.
database_cross_reference: CAS:38539-75-2
database_cross_reference: ChemSpiderID:13408232
database_cross_reference: ChemicalBookNo:CB93096577
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:18423149

3-pyridylcarbinol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-pyridylcarbinol.
has_exact_synonym: 3-PC
has_exact_synonym: Nicotinyl Alcohol
has_obo_namespace: XLMOD
id: XLMOD:09201

Axiom
annotated source: 3-pyridylcarbinol
annotated property: definition
annotated target: 3-pyridylcarbinol.
database_cross_reference: CAS:100-55-0
database_cross_reference: ChemSpiderID:7229
database_cross_reference: ChemicalBookNo:CB6384809
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:7510

phenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
subclass of: Restriction
  on property: is_reactive_with
  some values from: alpha-keto acid reactive
definition: Phenylhydrazine.
has_obo_namespace: XLMOD
id: XLMOD:09202

Axiom
annotated source: phenylhydrazine
annotated property: definition
annotated target: Phenylhydrazine.
database_cross_reference: CAS:100-63-0
database_cross_reference: ChemSpiderID:7235
database_cross_reference: ChemicalBookNo:CB9216819
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:7516

o-benzylhydroxylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: alpha-keto acid reactive
definition: O-benzylhydroxylamine.
has_exact_synonym: O-BHA
has_obo_namespace: XLMOD
id: XLMOD:09203

Axiom
annotated source: o-benzylhydroxylamine
annotated property: definition
annotated target: O-benzylhydroxylamine.
database_cross_reference: CAS:622-33-3
database_cross_reference: ChemSpiderID:92425
database_cross_reference: ChemicalBookNo:CB6853994
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:102313

o-phenylenediamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: alpha-keto acid reactive
definition: O-phenylenediamine.
has_obo_namespace: XLMOD
id: XLMOD:09204

Axiom
annotated source: o-phenylenediamine
annotated property: definition
annotated target: O-phenylenediamine.
database_cross_reference: CAS:95-54-5
database_cross_reference: ChemSpiderID:13837582
database_cross_reference: ChemicalBookNo:CB9854699
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:7243

benzyl alcohol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: citric acid reactive
definition: Benzyl alcohol.
has_obo_namespace: XLMOD
id: XLMOD:09205

Axiom
annotated source: benzyl alcohol
annotated property: definition
annotated target: Benzyl alcohol.
database_cross_reference: CAS:100-51-6
database_cross_reference: ChemSpiderID:13860335
database_cross_reference: ChemicalBookNo:CB3852587
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:244

4-hydroxymercuribenzoate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 4-hydroxymercuribenzoate.
has_exact_synonym: PHMB
has_obo_namespace: XLMOD
id: XLMOD:09206

Axiom
annotated source: 4-hydroxymercuribenzoate
annotated property: definition
annotated target: 4-hydroxymercuribenzoate.
database_cross_reference: ChemSpiderID:15605527
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:3647458

4-chloro-3,5-dinitrobenzotrifluoride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 4-chloro-3,5-dinitrobenzotrifluoride.
has_exact_synonym: CNBF
has_obo_namespace: XLMOD
id: XLMOD:09207

Axiom
annotated source: 4-chloro-3,5-dinitrobenzotrifluoride
annotated property: definition
annotated target: 4-chloro-3,5-dinitrobenzotrifluoride.
database_cross_reference: CAS:393-75-9
database_cross_reference: ChemSpiderID:9426
database_cross_reference: ChemicalBookNo:CB1329205
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:9809

omega-bromoacetonylquinolinium bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: Omega-bromoacetonylquinolinium bromide.
has_exact_synonym: BQB
has_obo_namespace: XLMOD
id: XLMOD:09208

Axiom
annotated source: omega-bromoacetonylquinolinium bromide
annotated property: definition
annotated target: Omega-bromoacetonylquinolinium bromide.
database_cross_reference: PMID:26477276

pentafluorophenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: Pentafluorophenylhydrazine.
has_obo_namespace: XLMOD
id: XLMOD:09209

Axiom
annotated source: pentafluorophenylhydrazine
annotated property: definition
annotated target: Pentafluorophenylhydrazine.
database_cross_reference: CAS:828-73-9
database_cross_reference: ChemSpiderID:12681
database_cross_reference: ChemicalBookNo:CB4730404
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:13236

7-(diethylamino)coumarin-3-carbohydrazide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazide
definition: 7-(diethylamino)coumarin-3-carbohydrazide.
has_exact_synonym: CHH
has_obo_namespace: XLMOD
id: XLMOD:09210

Axiom
annotated source: 7-(diethylamino)coumarin-3-carbohydrazide
annotated property: definition
annotated target: 7-(diethylamino)coumarin-3-carbohydrazide.
database_cross_reference: CAS:100343-98-4
database_cross_reference: ChemSpiderID:113172
database_cross_reference: ChemicalBookNo:CB0751313
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:127564

L-Carnosine
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
definition: L-Carnosine.
has_obo_namespace: XLMOD
id: XLMOD:09211

Axiom
annotated source: L-Carnosine
annotated property: definition
annotated target: L-Carnosine.
database_cross_reference: CAS:305-84-0
database_cross_reference: ChemSpiderID:388363
database_cross_reference: ChemicalBookNo:CB0433763
database_cross_reference: PMID:26477276
database_cross_reference: PubChem_Compound:439224

7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate.
has_exact_synonym: SBD-F
has_obo_namespace: XLMOD
id: XLMOD:09212

Axiom
annotated source: 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate
annotated property: definition
annotated target: 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate.
database_cross_reference: CAS:84806-27-9
database_cross_reference: ChemSpiderID:108691
database_cross_reference: ChemicalBookNo:CB0175393
database_cross_reference: PMID:27582321
database_cross_reference: PubChem_Compound:2737780

4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: halobenzofurazan
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole.
has_exact_synonym: 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonamide
has_exact_synonym: ABD-F
has_obo_namespace: XLMOD
id: XLMOD:09213

Axiom
annotated source: 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole.
database_cross_reference: CAS:91366-65-3
database_cross_reference: ChemSpiderID:108876
database_cross_reference: ChemicalBookNo:CB4102238
database_cross_reference: PMID:27582321
database_cross_reference: PubChem_Compound:122067

4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole.
has_exact_synonym: 4-nitro-7-piperazino-2,1,3-benzoxadiazole
has_exact_synonym: NBD-PZ
has_obo_namespace: XLMOD
id: XLMOD:09214

Axiom
annotated source: 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole.
database_cross_reference: CAS:139332-66-4
database_cross_reference: ChemSpiderID:8762060
database_cross_reference: ChemicalBookNo:CB1744464
database_cross_reference: PMID:27582321
database_cross_reference: PubChem_Compound:10586684

4-(aminosulfonyl)-7-(1-piperazinyl)-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-(aminosulfonyl)-7-(1-piperazinyl)-2,1,3-benzoxadiazole.
has_exact_synonym: 7-(1-Piperazinyl)-2,1,3-benzoxadiazole-4-sulfonamide
has_exact_synonym: ABD-PZ
has_obo_namespace: XLMOD
id: XLMOD:09215

Axiom
annotated source: 4-(aminosulfonyl)-7-(1-piperazinyl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(aminosulfonyl)-7-(1-piperazinyl)-2,1,3-benzoxadiazole.
database_cross_reference: ChemSpiderID:32684168
database_cross_reference: PMID:27582321

4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole.
has_exact_synonym: 7-(3-Isothiocyanato-1-pyrrolidinyl)-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
has_exact_synonym: DBD-PyNCS
has_obo_namespace: XLMOD
id: XLMOD:09216

Axiom
annotated source: 4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole.
database_cross_reference: ChemSpiderID:3315424
database_cross_reference: PMID:27582321

4-(N,N-dimethylaminosulfonyl)-7-(2-carboxylpyrrolidine-1-yl)-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 4-(N,N-dimethylaminosulfonyl)-7-(2-carboxylpyrrolidine-1-yl)-2,1,3-benzoxadiazole.
has_exact_synonym: DBD-Pro
has_obo_namespace: XLMOD
id: XLMOD:09217

Axiom
annotated source: 4-(N,N-dimethylaminosulfonyl)-7-(2-carboxylpyrrolidine-1-yl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(N,N-dimethylaminosulfonyl)-7-(2-carboxylpyrrolidine-1-yl)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:27582321

4-(N,N-dimethylaminosulfonyl)-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: halobenzofurazan
definition: 4-(N,N-dimethylaminosulfonyl)-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole.
has_exact_synonym: DBD-ProCOCl
has_obo_namespace: XLMOD
id: XLMOD:09218

Axiom
annotated source: 4-(N,N-dimethylaminosulfonyl)-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(N,N-dimethylaminosulfonyl)-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:27582321
database_cross_reference: PubChem_Compound:192501

4-nitro-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: halobenzofurazan
definition: 4-nitro-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole.
has_exact_synonym: NBD-ProCOCl
has_obo_namespace: XLMOD
id: XLMOD:09219

Axiom
annotated source: 4-nitro-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-nitro-7-(2-chroloformylpyrrolidine-1-yl)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:27582321

4-(2-carbazoylpyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-(2-carbazoylpyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole.
has_exact_synonym: DBD-ProCZ
has_obo_namespace: XLMOD
id: XLMOD:09220

Axiom
annotated source: 4-(2-carbazoylpyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(2-carbazoylpyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:27582321

4-(2-carbazoylpyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-(2-carbazoylpyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole.
has_exact_synonym: NBD-ProCZ
has_obo_namespace: XLMOD
id: XLMOD:09221

Axiom
annotated source: 4-(2-carbazoylpyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(2-carbazoylpyrrolidin-1-yl)-7-nitro-2,1,3-benzoxadiazole.
database_cross_reference: PMID:27582321

4-(N,N-dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-(N,N-dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole.
has_exact_synonym: 7-(3-Amino-1-pyrrolidinyl)-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide
has_exact_synonym: DBD-APy
has_obo_namespace: XLMOD
id: XLMOD:09222

Axiom
annotated source: 4-(N,N-dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-(N,N-dimethylaminosulfonyl)-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole.
database_cross_reference: ChemSpiderID:4320363
database_cross_reference: PMID:22761132
database_cross_reference: PMID:27582321

4-nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole.
has_exact_synonym: 1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-3-pyrrolidinamine
has_exact_synonym: NBD-APy
has_obo_namespace: XLMOD
id: XLMOD:09223

Axiom
annotated source: 4-nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-nitro-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole.
database_cross_reference: ChemSpiderID:3633688
database_cross_reference: PMID:27582321

1-(3-Aminopropyl)-3-bromoquinolinium bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 1-(3-Aminopropyl)-3-bromoquinolinium bromide.
has_exact_synonym: APBQ
has_obo_namespace: XLMOD
id: XLMOD:09224

Axiom
annotated source: 1-(3-Aminopropyl)-3-bromoquinolinium bromide
annotated property: definition
annotated target: 1-(3-Aminopropyl)-3-bromoquinolinium bromide.
database_cross_reference: PMID:27582321

(S)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: (S)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine.
has_exact_synonym: DMT-3(S)-Apy
has_obo_namespace: XLMOD
id: XLMOD:09225

Axiom
annotated source: (S)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine
annotated property: definition
annotated target: (S)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine.
database_cross_reference: PMID:26526912
database_cross_reference: PMID:27582321

(S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: (S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate.
has_exact_synonym: DMT-(S)-Pro-OSu
has_obo_namespace: XLMOD
id: XLMOD:09226

Axiom
annotated source: (S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate
annotated property: definition
annotated target: (S)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate.
database_cross_reference: PMID:26526912
database_cross_reference: PMID:27582321

(R)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: (R)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine.
has_exact_synonym: DMT-3(R)-Apy
has_obo_namespace: XLMOD
id: XLMOD:09227

Axiom
annotated source: (R)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine
annotated property: definition
annotated target: (R)-1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)pyrrolidin-3-amine.
database_cross_reference: PMID:26526912

(R)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: (R)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate.
has_exact_synonym: DMT-(R)-Pro-OSu
has_obo_namespace: XLMOD
id: XLMOD:09228

Axiom
annotated source: (R)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate
annotated property: definition
annotated target: (R)-2,5-dioxopyrrolidin-1-yl-1-(4,6-dimethoxy-1,3,5-triazin-2-yl) pyrrolidine-2-carboxylate.
database_cross_reference: PMID:26526912

(S)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: (S)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine.
has_exact_synonym: DMT-1(S)-Apy
has_obo_namespace: XLMOD
id: XLMOD:09229

Axiom
annotated source: (S)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine
annotated property: definition
annotated target: (S)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine.
database_cross_reference: PMID:25366977

(R)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: (R)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine.
has_exact_synonym: DMT-1(R)-Apy
has_obo_namespace: XLMOD
id: XLMOD:09230

Axiom
annotated source: (R)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine
annotated property: definition
annotated target: (R)-4,6-dimethoxy-N-(pyrrolidin-3-yl)-1,3,5-triazin-2-amine.
database_cross_reference: PMID:25366977

4-Methyl-1,2,4-triazole-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-Methyl-1,2,4-triazole-3,5-dione.
has_exact_synonym: 4-Methyl-TAD
has_exact_synonym: MTAD
has_obo_namespace: XLMOD
id: XLMOD:09231

Axiom
annotated source: 4-Methyl-1,2,4-triazole-3,5-dione
annotated property: definition
annotated target: 4-Methyl-1,2,4-triazole-3,5-dione.
database_cross_reference: ChemSpiderID:114186
database_cross_reference: PMID:27511712

4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: 4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione.
has_exact_synonym: DMAPTAD
has_obo_namespace: XLMOD
id: XLMOD:09232

Axiom
annotated source: 4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione
annotated property: definition
annotated target: 4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione.
database_cross_reference: ChemSpiderID:28468701
database_cross_reference: PMID:27511712

deuterium labelled 4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
definition: Deuterium labelled 4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione.
has_exact_synonym: DMAPTAD-d4
has_obo_namespace: XLMOD
id: XLMOD:09233

Axiom
annotated source: deuterium labelled 4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione
annotated property: definition
annotated target: Deuterium labelled 4-(4-dimethylaminophenyl)-1,2,4-triazole-3,5-dione.
database_cross_reference: ChemSpiderID:28468701
database_cross_reference: PMID:27511712

4-(4-diethylaminophenyl)-1,2,4-triazole-3,5-dione
type: Class
subclass of: Cookson type reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: TAD
subclass of: Restriction
  on property: is_labelled
  some values from: deuterium labelled
definition: 4-(4-diethylaminophenyl)-1,2,4-triazole-3,5-dione.
has_exact_synonym: DEAPTAD
has_obo_namespace: XLMOD
id: XLMOD:09234

Axiom
annotated source: 4-(4-diethylaminophenyl)-1,2,4-triazole-3,5-dione
annotated property: definition
annotated target: 4-(4-diethylaminophenyl)-1,2,4-triazole-3,5-dione.
database_cross_reference: PMID:27511712

2-hydrazino-4-trifluoromethylpyrimidine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 2-hydrazino-4-trifluoromethylpyrimidine.
has_exact_synonym: HTP
has_obo_namespace: XLMOD
id: XLMOD:09235

Axiom
annotated source: 2-hydrazino-4-trifluoromethylpyrimidine
annotated property: definition
annotated target: 2-hydrazino-4-trifluoromethylpyrimidine.
database_cross_reference: CAS:197305-97-8
database_cross_reference: ChemSpiderID:1064766
database_cross_reference: ChemicalBookNo:CB7444959
database_cross_reference: PMID:26454158
database_cross_reference: PubChem_Compound:1268079

N-methyl-nicotinic acid N-hydroxysuccinimide ester
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: N-methyl-nicotinic acid N-hydroxysuccinimide ester.
has_exact_synonym: MNAHS
has_obo_namespace: XLMOD
id: XLMOD:09236

Axiom
annotated source: N-methyl-nicotinic acid N-hydroxysuccinimide ester
annotated property: definition
annotated target: N-methyl-nicotinic acid N-hydroxysuccinimide ester.
database_cross_reference: PMID:26454158

o-(3-trimethylammoniumpropyl)hydroxylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: O-(3-trimethylammoniumpropyl)hydroxylamine.
has_exact_synonym: TMAPH
has_obo_namespace: XLMOD
id: XLMOD:09237

Axiom
annotated source: o-(3-trimethylammoniumpropyl)hydroxylamine
annotated property: definition
annotated target: O-(3-trimethylammoniumpropyl)hydroxylamine.
database_cross_reference: PMID:26454158

methoxylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: Methoxylamine.
has_exact_synonym: OMHA
has_exact_synonym: methoxyamine
has_obo_namespace: XLMOD
id: XLMOD:09238

Axiom
annotated source: methoxylamine
annotated property: definition
annotated target: Methoxylamine.
database_cross_reference: CAS:67-62-9
database_cross_reference: ChemSpiderID:3970
database_cross_reference: ChemicalBookNo:CB4931737
database_cross_reference: PMID:26454158
database_cross_reference: PubChem_Compound:4113

acetyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: acyl chloride
definition: Acetyl chloride.
has_obo_namespace: XLMOD
id: XLMOD:09239

Axiom
annotated source: acetyl chloride
annotated property: definition
annotated target: Acetyl chloride.
database_cross_reference: CAS:75-36-5
database_cross_reference: ChemSpiderID:6127
database_cross_reference: ChemicalBookNo:CB4485487
database_cross_reference: PMID:16458590
database_cross_reference: PubChem_Compound:6367

2,4-dinitrobenzoyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: acyl chloride
definition: 2,4-dinitrobenzoyl chloride.
has_exact_synonym: DNBC
has_obo_namespace: XLMOD
id: XLMOD:09240

Axiom
annotated source: 2,4-dinitrobenzoyl chloride
annotated property: definition
annotated target: 2,4-dinitrobenzoyl chloride.
database_cross_reference: CAS:20195-22-6
database_cross_reference: ChemSpiderID:79755
database_cross_reference: ChemicalBookNo:CB6933038
database_cross_reference: PMID:17765276
database_cross_reference: PubChem_Compound:88401

4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole.
has_exact_synonym: 7-Chloro-N-[2-(dimethylamino)ethyl]-2,1,3-benzoxadiazole-4-sulfonamide
has_exact_synonym: DAABD-Cl
has_obo_namespace: XLMOD
id: XLMOD:09241

Axiom
annotated source: 4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-(N,Ndimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole.
database_cross_reference: CAS:664985-43-7
database_cross_reference: ChemSpiderID:24589237
database_cross_reference: ChemicalBookNo:CB9423743
database_cross_reference: PMID:17590866
database_cross_reference: PubChem_Compound:44629802

4-nitrobenzenesulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
definition: 4-nitrobenzenesulfonyl chloride.
has_exact_synonym: 4-NBSC
has_exact_synonym: Nosyl chloride
has_obo_namespace: XLMOD
id: XLMOD:09242

Axiom
annotated source: 4-nitrobenzenesulfonyl chloride
annotated property: definition
annotated target: 4-nitrobenzenesulfonyl chloride.
database_cross_reference: CAS:98-74-8
database_cross_reference: ChemSpiderID:7126
database_cross_reference: ChemicalBookNo:CB7298161
database_cross_reference: PMID:16609843
database_cross_reference: PubChem_Compound:7404

Sanger type reagent
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl halide
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: A LC-MS derivatization reagent containing a fluoro-dinitrobenzene structure.
has_exact_synonym: Sanger's reagent
has_obo_namespace: XLMOD
id: XLMOD:09243

Axiom
annotated source: Sanger type reagent
annotated property: definition
annotated target: A LC-MS derivatization reagent containing a fluoro-dinitrobenzene structure.
database_cross_reference: PSI:XL

Marfey type reagent
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: membrane permeable
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl halide
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: amino acid reactive
definition: A LC-MS derivatization reagent containing a fluoro-dinitrophenyl structure.
has_exact_synonym: MR
has_exact_synonym: Marfey's reagent
has_obo_namespace: XLMOD
id: XLMOD:09244

Axiom
annotated source: Marfey type reagent
annotated property: definition
annotated target: A LC-MS derivatization reagent containing a fluoro-dinitrophenyl structure.
database_cross_reference: PSI:XL

N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide
type: Class
subclass of: chiral derivatization reagent
subclass of: Marfey type reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 2,4-dinitrophenyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl halide
definition: N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide.
has_exact_synonym: 1-Fluoro-2,4-dinitrophenyl-5-L-alanine amide
has_exact_synonym: L-FDAA
has_obo_namespace: XLMOD
id: XLMOD:09245

Axiom
annotated source: N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide
annotated property: definition
annotated target: N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide.
database_cross_reference: CAS:95713-52-3
database_cross_reference: ChemSpiderID:4589152
database_cross_reference: ChemicalBookNo:CB5413540
database_cross_reference: PubChem_Compound:5486955

N-(2,4-dinitro-5-fluorophenyl)-D-alaninamide
type: Class
subclass of: chiral derivatization reagent
subclass of: Marfey type reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 2,4-dinitrophenyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl halide
definition: N-(2,4-dinitro-5-fluorophenyl)-D-alaninamide.
has_exact_synonym: 1-Fluoro-2,4-dinitrophenyl-5-D-alanine amide
has_exact_synonym: D-FDAA
has_obo_namespace: XLMOD
id: XLMOD:09246

Axiom
annotated source: N-(2,4-dinitro-5-fluorophenyl)-D-alaninamide
annotated property: definition
annotated target: N-(2,4-dinitro-5-fluorophenyl)-D-alaninamide.
database_cross_reference: CAS:95713-52-3
database_cross_reference: ChemSpiderID:4589152
database_cross_reference: ChemicalBookNo:CB5413540
database_cross_reference: PubChem_Compound:5486955

N-(5-fluoro-2,4-dinitrophenyl)-L-leucinamide
type: Class
subclass of: chiral derivatization reagent
subclass of: Marfey type reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 2,4-dinitrophenyl
subclass of: Restriction
  on property: has_reactive_group
  some values from: aryl halide
definition: N-(5-fluoro-2,4-dinitrophenyl)-L-leucinamide.
has_exact_synonym: L-FDLA
has_obo_namespace: XLMOD
id: XLMOD:09247

Axiom
annotated source: N-(5-fluoro-2,4-dinitrophenyl)-L-leucinamide
annotated property: definition
annotated target: N-(5-fluoro-2,4-dinitrophenyl)-L-leucinamide.
database_cross_reference: PMID:26496130

hexyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: Hexyl chloroformate.
has_exact_synonym: HCF
has_obo_namespace: XLMOD
id: XLMOD:09248

Axiom
annotated source: hexyl chloroformate
annotated property: definition
annotated target: Hexyl chloroformate.
database_cross_reference: CAS:6092-54-2
database_cross_reference: ChemSpiderID:21071
database_cross_reference: ChemicalBookNo:CB2782111
database_cross_reference: PubChem_Compound:22466

1,2-Benzo-3,4-dihydrocarbazole-9-ethyl chloroformate
type: Class
subclass of: chloroformate reagent
definition: 1,2-Benzo-3,4-dihydrocarbazole-9-ethyl chloroformate.
has_exact_synonym: BCEOC
has_obo_namespace: XLMOD
id: XLMOD:09249

Axiom
annotated source: 1,2-Benzo-3,4-dihydrocarbazole-9-ethyl chloroformate
annotated property: definition
annotated target: 1,2-Benzo-3,4-dihydrocarbazole-9-ethyl chloroformate.
database_cross_reference: PMID:18970343

(-)-1-(9-fluorenyl)-ethyl chloroformate
type: Class
subclass of: chiral derivatization reagent
subclass of: chloroformate reagent
definition: (-)-1-(9-fluorenyl)-ethyl chloroformate.
has_exact_synonym: -FLEC
has_obo_namespace: XLMOD
id: XLMOD:09250

Axiom
annotated source: (-)-1-(9-fluorenyl)-ethyl chloroformate
annotated property: definition
annotated target: (-)-1-(9-fluorenyl)-ethyl chloroformate.
database_cross_reference: PMID:25082527

(+)-1-(9-fluorenyl)-ethyl chloroformate
type: Class
subclass of: chiral derivatization reagent
subclass of: chloroformate reagent
definition: (+)-1-(9-fluorenyl)-ethyl chloroformate.
has_exact_synonym: +FLEC
has_obo_namespace: XLMOD
id: XLMOD:09251

Axiom
annotated source: (+)-1-(9-fluorenyl)-ethyl chloroformate
annotated property: definition
annotated target: (+)-1-(9-fluorenyl)-ethyl chloroformate.
database_cross_reference: PMID:29785784

1,2-Benzo-3,4-dihydrocarbazole-9-ethyl-benzenesulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
subclass of: Restriction
  on property: is_reactive_with
  some values from: bile acid reactive
definition: 1,2-Benzo-3,4-dihydrocarbazole-9-ethyl-benzenesulfonate.
has_exact_synonym: BDEBS
has_obo_namespace: XLMOD
id: XLMOD:09252

Axiom
annotated source: 1,2-Benzo-3,4-dihydrocarbazole-9-ethyl-benzenesulfonate
annotated property: definition
annotated target: 1,2-Benzo-3,4-dihydrocarbazole-9-ethyl-benzenesulfonate.
database_cross_reference: PMID:17305246
database_cross_reference: PMID:19525080

2-(2,3-Naphthalimino)ethyl trifluoromethanesulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
definition: 2-(2,3-Naphthalimino)ethyl trifluoromethanesulfonate.
has_exact_synonym: 2-(2,3-Naphthalimino)ethyl trifluoromethanesulphonate
has_exact_synonym: NE-OTf
has_obo_namespace: XLMOD
id: XLMOD:09253

Axiom
annotated source: 2-(2,3-Naphthalimino)ethyl trifluoromethanesulfonate
annotated property: definition
annotated target: 2-(2,3-Naphthalimino)ethyl trifluoromethanesulfonate.
database_cross_reference: CAS:128651-50-3
database_cross_reference: ChemSpiderID:11563131
database_cross_reference: ChemicalBookNo:CB7667550_EN
database_cross_reference: DOI:10.2116/bunsekikagaku.53.161

4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-piperazino-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-piperazino-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-PZ
has_obo_namespace: XLMOD
id: XLMOD:09254

Axiom
annotated source: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-piperazino-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-piperazino-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17590866

4-[4-carbazoylpiperidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[4-carbazoylpiperidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-PiCZ
has_obo_namespace: XLMOD
id: XLMOD:09255

Axiom
annotated source: 4-[4-carbazoylpiperidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[4-carbazoylpiperidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17590866

4-[2-carbazoylpyrrolidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[2-carbazoylpyrrolidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-ProCZ
has_obo_namespace: XLMOD
id: XLMOD:09256

Axiom
annotated source: 4-[2-carbazoylpyrrolidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-carbazoylpyrrolidin-1-yl]-7-[2-(N,N-dimethylamino)ethylaminosulfonyl]-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17590866

4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-APy
has_obo_namespace: XLMOD
id: XLMOD:09257

Axiom
annotated source: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(3-aminopyrrolidin-1-yl)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17590866

4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-methylhydrazino-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-methylhydrazino-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-MHz
has_obo_namespace: XLMOD
id: XLMOD:09258

Axiom
annotated source: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-methylhydrazino-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-N-methylhydrazino-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17703478

4-[2-(N,N-dimethylamino) ethylaminosulfonyl]-7-(2-aminobutylamino)-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[2-(N,N-dimethylamino) ethylaminosulfonyl]-7-(2-aminobutylamino)-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-AB
has_obo_namespace: XLMOD
id: XLMOD:09259

Axiom
annotated source: 4-[2-(N,N-dimethylamino) ethylaminosulfonyl]-7-(2-aminobutylamino)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-(N,N-dimethylamino) ethylaminosulfonyl]-7-(2-aminobutylamino)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17703478

4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(2-aminopentylamino)-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(2-aminopentylamino)-2,1,3-benzoxadiazole.
has_exact_synonym: DAABD-AP
has_obo_namespace: XLMOD
id: XLMOD:09260

Axiom
annotated source: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(2-aminopentylamino)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[2-(N,N-dimethylamino)ethylaminosulfonyl]-7-(2-aminopentylamino)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17703478

[4-(4-N-methyl)piperazinosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: [4-(4-N-methyl)piperazinosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole.
has_exact_synonym: MePzBD-Cl
has_obo_namespace: XLMOD
id: XLMOD:09261

Axiom
annotated source: [4-(4-N-methyl)piperazinosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole
annotated property: definition
annotated target: [4-(4-N-methyl)piperazinosulfonyl]-7-(2-aminoethylamino)-2,1,3-benzoxadiazole.
database_cross_reference: PMID:17590866

[4-(4-N-methyl)-piperazinosulfonyl]-7-chloro-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: [4-(4-N-methyl)-piperazinosulfonyl]-7-chloro-2,1,3-benzoxadiazole.
has_exact_synonym: MePzBD-AE
has_obo_namespace: XLMOD
id: XLMOD:09262

Axiom
annotated source: [4-(4-N-methyl)-piperazinosulfonyl]-7-chloro-2,1,3-benzoxadiazole
annotated property: definition
annotated target: [4-(4-N-methyl)-piperazinosulfonyl]-7-chloro-2,1,3-benzoxadiazole.
database_cross_reference: PSI:XL

4-[[(N-hydrazinoformyl)methyl]-N-methyl]amino-7-[N,N-(dimethylamino)sulfonyl]-2,1,3-benzoxadiazole
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: benzofurazan
definition: 4-[[(N-hydrazinoformyl)methyl]-N-methyl]amino-7-[N,N-(dimethylamino)sulfonyl]-2,1,3-benzoxadiazole.
has_exact_synonym: DBD-COHZ
has_obo_namespace: XLMOD
id: XLMOD:09263

Axiom
annotated source: 4-[[(N-hydrazinoformyl)methyl]-N-methyl]amino-7-[N,N-(dimethylamino)sulfonyl]-2,1,3-benzoxadiazole
annotated property: definition
annotated target: 4-[[(N-hydrazinoformyl)methyl]-N-methyl]amino-7-[N,N-(dimethylamino)sulfonyl]-2,1,3-benzoxadiazole.
database_cross_reference: PMID:21639306

2,4-Dinitro-6-trifluoromethylphenylhydrazine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: hydrazine
definition: 2,4-Dinitro-6-trifluoromethylphenylhydrazine.
has_exact_synonym: DNFPH
has_obo_namespace: XLMOD
id: XLMOD:09264

Axiom
annotated source: 2,4-Dinitro-6-trifluoromethylphenylhydrazine
annotated property: definition
annotated target: 2,4-Dinitro-6-trifluoromethylphenylhydrazine.
database_cross_reference: CAS:119-26-6
database_cross_reference: ChemSpiderID:3001507
database_cross_reference: ChemicalBookNo:CB4852908
database_cross_reference: PMID:12502079
database_cross_reference: PubChem_Compound:3772977

2-Amino-N,N,N-trimethylethanaminium chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: 2-Amino-N,N,N-trimethylethanaminium chloride.
has_exact_synonym: CA
has_obo_namespace: XLMOD
id: XLMOD:09266

Axiom
annotated source: 2-Amino-N,N,N-trimethylethanaminium chloride
annotated property: definition
annotated target: 2-Amino-N,N,N-trimethylethanaminium chloride.
database_cross_reference: ChemSpiderID:2340954

4-(1'-cyanoisoindolyl)phenylisothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: 4-(1'-cyanoisoindolyl)phenylisothiocyanate.
has_exact_synonym: CIPIC
has_obo_namespace: XLMOD
id: XLMOD:09267

Axiom
annotated source: 4-(1'-cyanoisoindolyl)phenylisothiocyanate
annotated property: definition
annotated target: 4-(1'-cyanoisoindolyl)phenylisothiocyanate.
database_cross_reference: PMID:12485718

2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate
type: Class
subclass of: chiral derivatization reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate.
has_exact_synonym: GITC
has_exact_synonym: TAGIT
has_obo_namespace: XLMOD
id: XLMOD:09268

Axiom
annotated source: 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate
annotated property: definition
annotated target: 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate.
database_cross_reference: Beilstein:56699
database_cross_reference: CAS:14152-97-7
database_cross_reference: ChemSpiderID:89858
database_cross_reference: ChemicalBookNo:CB7320022
database_cross_reference: MDL:MFCD00043085
database_cross_reference: PMID:19662356
database_cross_reference: PubChem_Compound:99462

4-Dimethylaminophenyl isothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 4-Dimethylaminophenyl isothiocyanate.
has_exact_synonym: DMAPI
has_obo_namespace: XLMOD
id: XLMOD:09269

Axiom
annotated source: 4-Dimethylaminophenyl isothiocyanate
annotated property: definition
annotated target: 4-Dimethylaminophenyl isothiocyanate.
database_cross_reference: CAS:2131-64-8
database_cross_reference: ChemSpiderID:67599
database_cross_reference: ChemicalBookNo:CB6742874
database_cross_reference: PMID:23010846
database_cross_reference: PubChem_Compound:75047

dimethylaminoazobenzene isothiocyanate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: isothiocyanate
definition: Dimethylaminoazobenzene isothiocyanate.
has_exact_synonym: DABITC
has_obo_namespace: XLMOD
id: XLMOD:09270

Axiom
annotated source: dimethylaminoazobenzene isothiocyanate
annotated property: definition
annotated target: Dimethylaminoazobenzene isothiocyanate.
database_cross_reference: CAS:7612-98-8
database_cross_reference: ChemSpiderID:74082
database_cross_reference: ChemicalBookNo:74082
database_cross_reference: PMID:6426344
database_cross_reference: PubChem_Compound:82084

trimellitic anhydride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: anhydride
definition: Trimellitic anhydride.
has_exact_synonym: TMA
has_obo_namespace: XLMOD
id: XLMOD:09272

Axiom
annotated source: trimellitic anhydride
annotated property: definition
annotated target: Trimellitic anhydride.
database_cross_reference: CAS:552-30-7
database_cross_reference: ChemSpiderID:10618
database_cross_reference: ChemicalBookNo:CB5293056
database_cross_reference: PubChem_Compound:11089

3-bromoactonyltrimethylammonium bromide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 3-bromoactonyltrimethylammonium bromide.
has_exact_synonym: BTA
has_obo_namespace: XLMOD
id: XLMOD:09274

Axiom
annotated source: 3-bromoactonyltrimethylammonium bromide
annotated property: definition
annotated target: 3-bromoactonyltrimethylammonium bromide.
database_cross_reference: DOI:10.1016/j.trac.2014.03.013

5,5'-dimethyl-1,3-cyclohexanedione
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 5,5'-dimethyl-1,3-cyclohexanedione.
has_obo_namespace: XLMOD
id: XLMOD:09275

Axiom
annotated source: 5,5'-dimethyl-1,3-cyclohexanedione
annotated property: definition
annotated target: 5,5'-dimethyl-1,3-cyclohexanedione.
database_cross_reference: CAS:126-81-8
database_cross_reference: ChemSpiderID:29091
database_cross_reference: ChemicalBookNo:CB1741746
database_cross_reference: PubChem_Compound:31358

4-(dimethylamino)-benzoic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 4-(dimethylamino)-benzoic acid.
has_exact_synonym: DMBA
has_obo_namespace: XLMOD
id: XLMOD:09276

Axiom
annotated source: 4-(dimethylamino)-benzoic acid
annotated property: definition
annotated target: 4-(dimethylamino)-benzoic acid.
database_cross_reference: CAS:619-84-1
database_cross_reference: ChemSpiderID:11595
database_cross_reference: ChemicalBookNo:CB4190291
database_cross_reference: PubChem_Compound:12092

1,2-dimethylimidazole-4-sulfonyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonyl chloride
definition: 1,2-dimethylimidazole-4-sulfonyl chloride.
has_exact_synonym: DMISC
has_obo_namespace: XLMOD
id: XLMOD:09277

Axiom
annotated source: 1,2-dimethylimidazole-4-sulfonyl chloride
annotated property: definition
annotated target: 1,2-dimethylimidazole-4-sulfonyl chloride.
database_cross_reference: CAS:137049-02-6
database_cross_reference: ChemSpiderID:2017929
database_cross_reference: ChemicalBookNo:CB3236772
database_cross_reference: PubChem_Compound:2736256

N-(2-ferroceneethyl)maleimide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: N-(2-ferroceneethyl)maleimide.
has_exact_synonym: FEM
has_obo_namespace: XLMOD
id: XLMOD:09278

Axiom
annotated source: N-(2-ferroceneethyl)maleimide
annotated property: definition
annotated target: N-(2-ferroceneethyl)maleimide.
database_cross_reference: ChemSpiderID:10158611

ferrocenecarboxylic acid-(2-maleimidoyl)ethylamide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: maleimide
definition: Ferrocenecarboxylic acid-(2-maleimidoyl)ethylamide.
has_exact_synonym: FMEA
has_obo_namespace: XLMOD
id: XLMOD:09279

Axiom
annotated source: ferrocenecarboxylic acid-(2-maleimidoyl)ethylamide
annotated property: definition
annotated target: Ferrocenecarboxylic acid-(2-maleimidoyl)ethylamide.
database_cross_reference: DOI:10.1016/j.trac.2014.03.013

heptadecafluoroundecylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: sialic acid reactive
definition: Heptadecafluoroundecylamine.
has_exact_synonym: HFUA
has_obo_namespace: XLMOD
id: XLMOD:09280

Axiom
annotated source: heptadecafluoroundecylamine
annotated property: definition
annotated target: Heptadecafluoroundecylamine.
database_cross_reference: DOI:10.1016/j.trac.2014.03.013

4-hydrazino-N,N,N-trimethyl-4-oxobutanaminium iodide
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: aldehyde reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: ketone reactive
definition: 4-hydrazino-N,N,N-trimethyl-4-oxobutanaminium iodide.
has_exact_synonym: HTMOB
has_obo_namespace: XLMOD
id: XLMOD:09281

Axiom
annotated source: 4-hydrazino-N,N,N-trimethyl-4-oxobutanaminium iodide
annotated property: definition
annotated target: 4-hydrazino-N,N,N-trimethyl-4-oxobutanaminium iodide.
database_cross_reference: DOI:10.1016/j.trac.2014.03.013

3-aminophenylboronic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: boronic acid
subclass of: Restriction
  on property: is_reactive_with
  some values from: steroid reactive
definition: 3-aminophenylboronic acid.
has_exact_synonym: m-APBA
has_obo_namespace: XLMOD
id: XLMOD:09282

Axiom
annotated source: 3-aminophenylboronic acid
annotated property: definition
annotated target: 3-aminophenylboronic acid.
database_cross_reference: CAS:280563-63-5
database_cross_reference: ChemSpiderID:83303
database_cross_reference: ChemicalBookNo:CB3357729
database_cross_reference: PubChem_Compound:92269

1,2-naphthoquinone-4-sulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 1,2-naphthoquinone-4-sulfonate.
has_exact_synonym: 3,4-dihydro-3,4-dioxonaphthalene-1-sulphonic acid
has_exact_synonym: NQS
has_obo_namespace: XLMOD
id: XLMOD:09283

Axiom
annotated source: 1,2-naphthoquinone-4-sulfonate
annotated property: definition
annotated target: 1,2-naphthoquinone-4-sulfonate.
database_cross_reference: CAS:2066-93-5
database_cross_reference: ChemSpiderID:10191
database_cross_reference: ChemicalBookNo:CB4898119
database_cross_reference: PubChem_Compound:10637

2-bromo-4'-chloroacetophenone
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: sulfhydryl reactive
definition: 2-bromo-4'-chloroacetophenone.
has_exact_synonym: 4-Chloro-2'-bromoacetophenone
has_exact_synonym: p-CPB
has_obo_namespace: XLMOD
id: XLMOD:09284

Axiom
annotated source: 2-bromo-4'-chloroacetophenone
annotated property: definition
annotated target: 2-bromo-4'-chloroacetophenone.
database_cross_reference: CAS:536-38-9
database_cross_reference: ChemSpiderID:61599
database_cross_reference: ChemicalBookNo:CB4198611
database_cross_reference: PubChem_Compound:68303

1-pyrenemethylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 1-pyrenemethylamine.
has_exact_synonym: PMA
has_obo_namespace: XLMOD
id: XLMOD:09285

Axiom
annotated source: 1-pyrenemethylamine
annotated property: definition
annotated target: 1-pyrenemethylamine.
database_cross_reference: CAS:3786-54-7
database_cross_reference: ChemSpiderID:2073158
database_cross_reference: PubChem_Compound:2794252

succinimidylferrocenyl propionate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: Succinimidylferrocenyl propionate.
has_exact_synonym: SFP
has_obo_namespace: XLMOD
id: XLMOD:09286

Axiom
annotated source: succinimidylferrocenyl propionate
annotated property: definition
annotated target: Succinimidylferrocenyl propionate.
database_cross_reference: PubChem_Compound:129849850

N-succinimidyl-2(3-pyridyl)acetate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: N-succinimidyl-2(3-pyridyl)acetate.
has_exact_synonym: SPA
has_obo_namespace: XLMOD
id: XLMOD:09287

Axiom
annotated source: N-succinimidyl-2(3-pyridyl)acetate
annotated property: definition
annotated target: N-succinimidyl-2(3-pyridyl)acetate.
database_cross_reference: DOI:10.1016/j.trac.2014.03.013

7-chloro-2,1,3-benzoxadiazole-4-sulfonylaminoethyltrimethylammonium chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: thiol reactive
definition: 7-chloro-2,1,3-benzoxadiazole-4-sulfonylaminoethyltrimethylammonium chloride.
has_exact_synonym: TAABD-Cl
has_obo_namespace: XLMOD
id: XLMOD:09288

Axiom
annotated source: 7-chloro-2,1,3-benzoxadiazole-4-sulfonylaminoethyltrimethylammonium chloride
annotated property: definition
annotated target: 7-chloro-2,1,3-benzoxadiazole-4-sulfonylaminoethyltrimethylammonium chloride.
database_cross_reference: DOI:10.1016/j.trac.2014.03.013

1,2-benzo-3,4-dihydrocarbazole-9-p-toluenesulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
subclass of: Restriction
  on property: is_reactive_with
  some values from: bile acid reactive
definition: 1,2-benzo-3,4-dihydrocarbazole-9-p-toluenesulfonate.
has_exact_synonym: BDETS
has_obo_namespace: XLMOD
id: XLMOD:09289

Axiom
annotated source: 1,2-benzo-3,4-dihydrocarbazole-9-p-toluenesulfonate
annotated property: definition
annotated target: 1,2-benzo-3,4-dihydrocarbazole-9-p-toluenesulfonate.
database_cross_reference: PMID:17305246

tetramethylammonium hydroxide
type: Class
subclass of: LCMS derivatization reagent
definition: Tetramethylammonium hydroxide.
has_exact_synonym: TMAH
has_obo_namespace: XLMOD
id: XLMOD:09290

Axiom
annotated source: tetramethylammonium hydroxide
annotated property: definition
annotated target: Tetramethylammonium hydroxide.
database_cross_reference: CAS:75-59-2
database_cross_reference: ChemSpiderID:54928
database_cross_reference: ChemicalBookNo:CB2854236
database_cross_reference: PMID:19525080
database_cross_reference: PubChem_Compound:60966

trimethylsulfonium hydroxide
type: Class
subclass of: alkylation reagent
subclass of: LCMS derivatization reagent
definition: Trimethylsulfonium hydroxide.
has_exact_synonym: TMSH
has_obo_namespace: XLMOD
id: XLMOD:09291

Axiom
annotated source: trimethylsulfonium hydroxide
annotated property: definition
annotated target: Trimethylsulfonium hydroxide.
database_cross_reference: CAS:17287-03-5
database_cross_reference: ChemSpiderID:9280449
database_cross_reference: ChemicalBookNo:CB1421127
database_cross_reference: PMID:19525080
database_cross_reference: PubChem_Compound:11105313

1-[2-(p-toluenesulfonate)-ethyl]-2-phenylimidazole-[4,5-f-]-9,10-phenantrene
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
definition: 1-[2-(p-toluenesulfonate)-ethyl]-2-phenylimidazole-[4,5-f-]-9,10-phenantrene.
has_exact_synonym: TSPP
has_obo_namespace: XLMOD
id: XLMOD:09292

Axiom
annotated source: 1-[2-(p-toluenesulfonate)-ethyl]-2-phenylimidazole-[4,5-f-]-9,10-phenantrene
annotated property: definition
annotated target: 1-[2-(p-toluenesulfonate)-ethyl]-2-phenylimidazole-[4,5-f-]-9,10-phenantrene.
database_cross_reference: PMID:19525080

1-pyrenyldiazomethane
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
definition: 1-pyrenyldiazomethane.
has_exact_synonym: PDAM
has_obo_namespace: XLMOD
id: XLMOD:09293

Axiom
annotated source: 1-pyrenyldiazomethane
annotated property: definition
annotated target: 1-pyrenyldiazomethane.
database_cross_reference: CAS:78377-23-8
database_cross_reference: ChemSpiderID:2043377
database_cross_reference: ChemicalBookNo:CB1374735
database_cross_reference: DOI:10.1016/j.trac.2011.05.005
database_cross_reference: PubChem_Compound:2762674

4- bromomethyl-6,7-methylenedioxycoumarin
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 4- bromomethyl-6,7-methylenedioxycoumarin.
has_exact_synonym: Br-MDC
has_obo_namespace: XLMOD
id: XLMOD:09294

Axiom
annotated source: 4- bromomethyl-6,7-methylenedioxycoumarin
annotated property: definition
annotated target: 4- bromomethyl-6,7-methylenedioxycoumarin.
database_cross_reference: CAS:97744-84-8
database_cross_reference: ChemSpiderID:112631
database_cross_reference: ChemicalBookNo:CB71326458
database_cross_reference: PMID:19525080
database_cross_reference: PubChem_Compound:126818

9-anthryldiazomethane
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
definition: 9-anthryldiazomethane.
has_exact_synonym: ADAM
has_obo_namespace: XLMOD
id: XLMOD:09295

Axiom
annotated source: 9-anthryldiazomethane
annotated property: definition
annotated target: 9-anthryldiazomethane.
database_cross_reference: CAS:10401-59-9
database_cross_reference: ChemSpiderID:2299498
database_cross_reference: ChemicalBookNo:CB1185515
database_cross_reference: PMID:19525080
database_cross_reference: PubChem_Compound:3035201

4-bromomethyl-7,8-benzcoumarin
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
definition: 4-bromomethyl-7,8-benzcoumarin.
has_exact_synonym: BrMBC
has_obo_namespace: XLMOD
id: XLMOD:09296

Axiom
annotated source: 4-bromomethyl-7,8-benzcoumarin
annotated property: definition
annotated target: 4-bromomethyl-7,8-benzcoumarin.
database_cross_reference: PMID:7866666

4-diazomethyl-7-methoxycoumarin
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
definition: 4-diazomethyl-7-methoxycoumarin.
has_exact_synonym: DMMC
has_obo_namespace: XLMOD
id: XLMOD:09297

Axiom
annotated source: 4-diazomethyl-7-methoxycoumarin
annotated property: definition
annotated target: 4-diazomethyl-7-methoxycoumarin.
database_cross_reference: CAS:84471-16-9
database_cross_reference: PMID:7866666
database_cross_reference: PubChem_Compound:54478954

4-bromomethyl-7-acetoxycoumarin
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
definition: 4-bromomethyl-7-acetoxycoumarin.
has_exact_synonym: 7-Acetoxy-4-bromomethylcoumarin
has_exact_synonym: BrMAC
has_obo_namespace: XLMOD
id: XLMOD:09298

Axiom
annotated source: 4-bromomethyl-7-acetoxycoumarin
annotated property: definition
annotated target: 4-bromomethyl-7-acetoxycoumarin.
database_cross_reference: CAS:2747-04-8
database_cross_reference: ChemSpiderID:163663
database_cross_reference: ChemicalBookNo:CB3141928
database_cross_reference: PMID:7866666
database_cross_reference: PubChem_Compound:188296

4-bromomethyl-6,7-dimethoxycoumarin
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
definition: 4-bromomethyl-6,7-dimethoxycoumarin.
has_exact_synonym: BrDMC
has_obo_namespace: XLMOD
id: XLMOD:09299

Axiom
annotated source: 4-bromomethyl-6,7-dimethoxycoumarin
annotated property: definition
annotated target: 4-bromomethyl-6,7-dimethoxycoumarin.
database_cross_reference: CAS:88404-25-5
database_cross_reference: ChemSpiderID:114199
database_cross_reference: ChemicalBookNo:CB8200312
database_cross_reference: PMID:7866666
database_cross_reference: PubChem_Compound:128870

N-(1-naphthyl)ethylene diamine dihydrochloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: N-(1-naphthyl)ethylene diamine dihydrochloride.
has_exact_synonym: NEDA
has_obo_namespace: XLMOD
id: XLMOD:09300

Axiom
annotated source: N-(1-naphthyl)ethylene diamine dihydrochloride
annotated property: definition
annotated target: N-(1-naphthyl)ethylene diamine dihydrochloride.
database_cross_reference: CAS:1465-25-4
database_cross_reference: ChemSpiderID:14378
database_cross_reference: ChemicalBookNo:CB4853112
database_cross_reference: PMID:19525080
database_cross_reference: PubChem_Compound:15106

9-aminophenanthrene
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: 9-aminophenanthrene.
has_exact_synonym: 9-AP
has_obo_namespace: XLMOD
id: XLMOD:09301

Axiom
annotated source: 9-aminophenanthrene
annotated property: definition
annotated target: 9-aminophenanthrene.
database_cross_reference: CAS:947-73-9
database_cross_reference: ChemSpiderID:13102
database_cross_reference: ChemicalBookNo:CB2175009
database_cross_reference: PMID:6707158
database_cross_reference: PubChem_Compound:13695

2-[p-(5,6-Methylenedioxy-2H-benzotriazol-2-yl)]phenethylamine
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_property
  some values from: fluorescent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: 2-[p-(5,6-Methylenedioxy-2H-benzotriazol-2-yl)]phenethylamine.
has_exact_synonym: MBPA
has_obo_namespace: XLMOD
id: XLMOD:09302

Axiom
annotated source: 2-[p-(5,6-Methylenedioxy-2H-benzotriazol-2-yl)]phenethylamine
annotated property: definition
annotated target: 2-[p-(5,6-Methylenedioxy-2H-benzotriazol-2-yl)]phenethylamine.
database_cross_reference: PMID:19525080

succinimidyloxycarbonylmethyl tris(2,4,6-trimethoxyphenyl)phosphonium bromide
type: Class
subclass of: LCMS derivatization reagent
definition: Succinimidyloxycarbonylmethyl tris(2,4,6-trimethoxyphenyl)phosphonium bromide.
has_exact_synonym: TMPP-Ac-OSu
has_obo_namespace: XLMOD
id: XLMOD:09303

Axiom
annotated source: succinimidyloxycarbonylmethyl tris(2,4,6-trimethoxyphenyl)phosphonium bromide
annotated property: definition
annotated target: Succinimidyloxycarbonylmethyl tris(2,4,6-trimethoxyphenyl)phosphonium bromide.
database_cross_reference: ChemSpiderID:24769591
database_cross_reference: PMID:20533316

9-(hydroxymethyl)anthracene
type: Class
subclass of: LCMS derivatization reagent
definition: 9-(hydroxymethyl)anthracene.
has_exact_synonym: 9-Anthracenemethanol
has_exact_synonym: HMA
has_obo_namespace: XLMOD
id: XLMOD:09304

Axiom
annotated source: 9-(hydroxymethyl)anthracene
annotated property: definition
annotated target: 9-(hydroxymethyl)anthracene.
database_cross_reference: CAS:1468-95-7
database_cross_reference: ChemSpiderID:66482
database_cross_reference: ChemicalBookNo:CB1205101
database_cross_reference: PMID:20533316
database_cross_reference: PubChem_Compound:73848

5-dimethylamino-1-naphthalenesulfonyl aminoethanol
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 5-dimethylamino-1-naphthalenesulfonyl aminoethanol.
has_exact_synonym: DNS-AE
has_obo_namespace: XLMOD
id: XLMOD:09305

Axiom
annotated source: 5-dimethylamino-1-naphthalenesulfonyl aminoethanol
annotated property: definition
annotated target: 5-dimethylamino-1-naphthalenesulfonyl aminoethanol.
database_cross_reference: PMID:20533316

2-(anthracene-2,3-dicarboximdo)ethyl-trifluoromethanesulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
definition: 2-(anthracene-2,3-dicarboximdo)ethyl-trifluoromethanesulfonate.
has_exact_synonym: AE-OTf
has_obo_namespace: XLMOD
id: XLMOD:09306

Axiom
annotated source: 2-(anthracene-2,3-dicarboximdo)ethyl-trifluoromethanesulfonate
annotated property: definition
annotated target: 2-(anthracene-2,3-dicarboximdo)ethyl-trifluoromethanesulfonate.
database_cross_reference: PMID:19525080

2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: sulfonate
definition: 2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate.
has_exact_synonym: NOEPES
has_obo_namespace: XLMOD
id: XLMOD:09307

Axiom
annotated source: 2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate
annotated property: definition
annotated target: 2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate.
database_cross_reference: ChemSpiderID:67166452
database_cross_reference: PMID:19525080

N-(4-Amidobutyl)-N-ethylisoluminol
type: Class
subclass of: LCMS derivatization reagent
definition: N-(4-Amidobutyl)-N-ethylisoluminol.
has_exact_synonym: ABEI
has_obo_namespace: XLMOD
id: XLMOD:09308

Axiom
annotated source: N-(4-Amidobutyl)-N-ethylisoluminol
annotated property: definition
annotated target: N-(4-Amidobutyl)-N-ethylisoluminol.
database_cross_reference: CAS:66612-29-1
database_cross_reference: ChemSpiderID:170196
database_cross_reference: ChemicalBookNo:CB8393526
database_cross_reference: PMID:19525080
database_cross_reference: PubChem_Compound:196441

6-[N-(4-aminobutyl)methylamino]-2,3-dihydro-1,4-phthalazinedione
type: Class
subclass of: LCMS derivatization reagent
definition: 6-[N-(4-aminobutyl)methylamino]-2,3-dihydro-1,4-phthalazinedione.
has_exact_synonym: ABMI
has_obo_namespace: XLMOD
id: XLMOD:09309

Axiom
annotated source: 6-[N-(4-aminobutyl)methylamino]-2,3-dihydro-1,4-phthalazinedione
annotated property: definition
annotated target: 6-[N-(4-aminobutyl)methylamino]-2,3-dihydro-1,4-phthalazinedione.
database_cross_reference: PMID:19525080

6-[N-(3-propionohydrazino)thioureido]benzo[g]-phthalazine-1,4-(2H,3H)-dione
type: Class
subclass of: LCMS derivatization reagent
definition: 6-[N-(3-propionohydrazino)thioureido]benzo[g]-phthalazine-1,4-(2H,3H)-dione.
has_exact_synonym: PRBO
has_obo_namespace: XLMOD
id: XLMOD:09310

Axiom
annotated source: 6-[N-(3-propionohydrazino)thioureido]benzo[g]-phthalazine-1,4-(2H,3H)-dione
annotated property: definition
annotated target: 6-[N-(3-propionohydrazino)thioureido]benzo[g]-phthalazine-1,4-(2H,3H)-dione.
database_cross_reference: PMID:19525080

triethylamine
type: Class
subclass of: LCMS derivatization reagent
definition: Triethylamine.
has_exact_synonym: TEA
has_obo_namespace: XLMOD
id: XLMOD:09311

Axiom
annotated source: triethylamine
annotated property: definition
annotated target: Triethylamine.
database_cross_reference: CAS:121-44-8
database_cross_reference: ChemSpiderID:8158
database_cross_reference: ChemicalBookNo:CB5355941
database_cross_reference: PubChem_Compound:8471

trifluoroacetic acid
type: Class
subclass of: LCMS derivatization reagent
definition: Trifluoroacetic acid.
has_exact_synonym: TFA
has_obo_namespace: XLMOD
id: XLMOD:09312

Axiom
annotated source: trifluoroacetic acid
annotated property: definition
annotated target: Trifluoroacetic acid.
database_cross_reference: CAS:76-05-1
database_cross_reference: ChemSpiderID:10239201
database_cross_reference: ChemicalBookNo:CB5127175
database_cross_reference: PubChem_Compound:6422

p-Bromophenacylate
type: Class
subclass of: acylation reagent
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_fluorophore
  some values from: 4-bromophenacyl
subclass of: Restriction
  on property: is_reactive_with
  some values from: carboxyl reactive
definition: 4-Bromophenacylate.
has_exact_synonym: Phenacyl-8
has_obo_namespace: XLMOD
id: XLMOD:09313

Axiom
annotated source: p-Bromophenacylate
annotated property: definition
annotated target: 4-Bromophenacylate.
database_cross_reference: PSI:XL

Dabsyl chloride
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: has_reactive_group
  some values from: amine reactive group
definition: Dabsyl chloride.
has_exact_synonym: DAB-Cl
has_obo_namespace: XLMOD
id: XLMOD:09314

Axiom
annotated source: Dabsyl chloride
annotated property: definition
annotated target: Dabsyl chloride.
database_cross_reference: Beilstein:3064095
database_cross_reference: CAS:56512-49-3
database_cross_reference: ChemSpiderID:82763
database_cross_reference: ChemicalBookNo:CB3699737
database_cross_reference: MDL:MFCD00007444
database_cross_reference: PubChem_Compound:91660

2,2-dihydroxyindane-1,3-dione
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
subclass of: Restriction
  on property: is_reactive_with
  some values from: secondary amine reactive
definition: 2,2-dihydroxyindane-1,3-dione.
has_exact_synonym: Ninhydrin
has_obo_namespace: XLMOD
id: XLMOD:09315

Axiom
annotated source: 2,2-dihydroxyindane-1,3-dione
annotated property: definition
annotated target: 2,2-dihydroxyindane-1,3-dione.
database_cross_reference: CAS:485-47-2
database_cross_reference: ChemSpiderID:9819
database_cross_reference: ChemicalBookNo:CB1337916
database_cross_reference: PubChem_Compound:10236

2,4,6-trinitrobenzenesulfonic acid
type: Class
subclass of: LCMS derivatization reagent
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: 2,4,6-trinitrobenzenesulfonic acid.
has_exact_synonym: Picrylsulfonic acid
has_exact_synonym: TNBSA
has_obo_namespace: XLMOD
id: XLMOD:09316

Axiom
annotated source: 2,4,6-trinitrobenzenesulfonic acid
annotated property: definition
annotated target: 2,4,6-trinitrobenzenesulfonic acid.
database_cross_reference: CAS:2508-19-2
database_cross_reference: ChemSpiderID:10577
database_cross_reference: ChemicalBookNo:CB3737855
database_cross_reference: PubChem_Compound:11045

DSAU
type: Class
subclass of: homofunctional cross-linker
subclass of: Restriction
  on property: has_reactive_group
  some values from: NHS ester
subclass of: Restriction
  on property: is_cleavable
  some values from: CID cleavable
definition: Urea crosslinker – C2-arm, NHS ester (DSAU)
bridge formula: C5 H4 N2 O3
mono isotopic mass: 140.02219198
reaction sites: 2
spacer length: 7.7
has_exact_synonym: C2-Urea-NHS-crosslinker
has_exact_synonym: DSAU
has_exact_synonym: Urea-crosslinker C2-succinimide
has_obo_namespace: XLMOD
id: XLMOD:09317

Axiom
annotated source: DSAU
annotated property: definition
annotated target: Urea crosslinker – C2-arm, NHS ester (DSAU)
database_cross_reference: PSI:XL

enzymatic generated cross-link
type: Class
subclass of: cross-linking entity
definition: Indicates that a cross-linker is generated through an enzymatic reaction.
has_obo_namespace: XLMOD
id: XLMOD:09318

Axiom
annotated source: enzymatic generated cross-link
annotated property: definition
annotated target: Indicates that a cross-linker is generated through an enzymatic reaction.
database_cross_reference: PSI:XL

transglutaminase generated
type: Class
subclass of: enzymatic generated cross-link
definition: protein-glutamine gamma-glutamyltransferase.Indicates that a cross-linker is generated by a transglutaminase enzymatic reaction.
has_obo_namespace: XLMOD
id: XLMOD:09319

Axiom
annotated source: transglutaminase generated
annotated property: definition
annotated target: protein-glutamine gamma-glutamyltransferase.Indicates that a cross-linker is generated by a transglutaminase enzymatic reaction.
database_cross_reference: EC 2.3.2.13
database_cross_reference: Expasy:2.3.2.13
database_cross_reference: KEGG:ENZYME: 2.3.2.13

QKiso
type: Class
subclass of: heterofunctional cross-linker
subclass of: zero-length cross-linker
subclass of: Restriction
  on property: is_labelled
  some values from: enzymatic generated cross-link
subclass of: Restriction
  on property: is_labelled
  some values from: transglutaminase generated
subclass of: Restriction
  on property: is_reactive_with
  some values from: primary amine reactive
definition: epsilon-(gamma-L-Glutamyl)lysine
bridge formula: -H3 -N1
mono isotopic mass: -17.026549
reaction sites: 2
specificities: (Q)&(K)
has_exact_synonym: QK-XL
has_exact_synonym: TG
has_exact_synonym: TG-XL
has_exact_synonym: Xlink:QKisopeptide
has_obo_namespace: XLMOD
id: XLMOD:09320

Axiom
annotated source: QKiso
annotated property: definition
annotated target: epsilon-(gamma-L-Glutamyl)lysine
database_cross_reference: CAS Registry Number:17105-15-6
database_cross_reference: CHEBI:133752
database_cross_reference: ChemSpider ID:5378717
database_cross_reference: PubChem CID:7015685
database_cross_reference: PubChem_Compound:4093968
database_cross_reference: Unimod:2026