Plate,Well Number,Well,Plate_Well,Characteristics [Organism],Term Source 1 REF,Term Source 1 Accession,Characteristics [Strain],Gene Identifier,Gene Symbol,Gene Symbol Synonyms,Gene Description,GO Biological Process,GO Molecular Function,GO Cellular Component,GO Term,Reagent Design Gene Annotation Build,Analysis Gene Annotation Build,Batch,Control Type,Control Comments,Quality Control,Channels,Comments,Number Of Cells,Number of Cells with Foci,Percentage Cells With Foci,Author Hit,Has Phenotype,Phenotype Annotation Level,Phenotype 1,Phenotype 1 Term Name,Phenotype 1 Term Accession P101,1,A1,P101_A1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P101,2,A2,P101_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL068C,PAU8,,"Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions","sporulation resulting in formation of a cellular spore, transcription, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, cellular_component, molecular_function, sporulation, transcription",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,7,3.2,no,,,,, P101,3,A3,P101_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL067C,SEO1,,"Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,20,7.6,no,,,,, P101,4,A4,P101_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL066W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,8,3.6,no,,,,, P101,5,A5,P101_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL065C,,,Putative protein of unknown function; has homology to FLO1; possible pseudogene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,11,4.8,no,,,,, P101,6,A6,P101_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL062W,GDH3,FUN51,"NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources",cellular amino acid and derivative metabolic process,oxidoreductase activity,"nucleus, mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, nucleus, other, oxidoreductase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,6,2.3,no,,,,, P101,7,A7,P101_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL061W,BDH2,,Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3,biological_process,oxidoreductase activity,"nucleus, cytoplasm","biological_process, cytoplasm, nucleus, oxidoreductase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,12,5.8,no,,,,, P101,8,A8,P101_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL060W,BDH1,"(2R,3R)-2,3-butanediol dehydrogenase;BDH","NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source",other,oxidoreductase activity,cytoplasm,"cytoplasm, other, oxidoreductase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,6,2.7,no,,,,, P101,9,A9,P101_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL059W,ECM1,,Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm,"transport, fungal-type cell wall organization, ribosome biogenesis",molecular_function,"nucleus, nucleolus","cell wall organization and biogenesis, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis, transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,6,3.3,no,,,,, P101,10,A10,P101_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL058W,CNE1,FUN48,"Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast","protein folding, cellular protein catabolic process",protein binding,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein binding, protein catabolic process, protein folding",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,0,0,no,,,,, P101,11,A11,P101_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL056W,GPB2,KRH1,"Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p","signaling process, transcription, response to chemical stimulus, sporulation resulting in formation of a cellular spore, pseudohyphal growth, RNA metabolic process","enzyme regulator activity, signal transducer activity, protein binding","mitochondrion, membrane, cytoplasm, plasma membrane","RNA metabolic process, cytoplasm, enzyme regulator activity, mitochondrion, other, plasma membrane, protein binding, pseudohyphal growth, response to chemical stimulus, signal transducer activity, signal transduction, sporulation, transcription",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,288,12,4.2,no,,,,, P101,12,A12,P101_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL055W,PEX22,YAF5,"Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation","transport, signaling process, peroxisome organization",protein binding,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, peroxisome, protein binding, signal transduction, transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,20,9.6,no,,,,, P101,13,B1,P101_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL053W,FLC2,HUF2,Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance,"transport, protein folding",transporter activity,"endoplasmic reticulum, cytoplasm","cell wall organization and biogenesis, cytoplasm, endoplasmic reticulum, protein folding, transport, transporter activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,3,1.3,no,,,,, P101,14,B2,P101_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL051W,OAF1,YAF1,"Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis","cellular lipid metabolic process, transcription, peroxisome organization","transcription regulator activity, DNA binding",nucleus,"DNA binding, lipid metabolic process, nucleus, organelle organization and biogenesis, response to chemical stimulus, transcription, transcription regulator activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,3,1.4,no,,,,, P101,15,B3,P101_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL049C,AIM2,,Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,12,4,no,,,,, P101,16,B4,P101_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL048C,GEM1,GON1,"Evolutionarily-conserved tail-anchored outer mitochondrial membrane GTPase which regulates mitochondrial morphology; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; not required for pheromone-induced cell death","transport, vesicle-mediated transport, mitochondrion organization",hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, vesicle-mediated transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,14,6.2,no,,,,, P101,17,B5,P101_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL046C,AIM1,,Protein involved in mitochondrial function or organization; null mutant displays elevated frequency of mitochondrial genome loss,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,10,4.5,no,,,,, P101,18,B6,P101_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL045C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps YAL044W-A",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,5,2.6,no,,,,, P101,19,B7,P101_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL044C,GCV3,,"H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF","cellular amino acid and derivative metabolic process, protein modification process",oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, other, oxidoreductase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,8,3.8,no,,,,, P101,20,B8,P101_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL042W,ERV46,FUN9,"Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fusion stage of transport","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, endoplasmic reticulum, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, endoplasmic reticulum, membrane, molecular_function, transport, vesicle-mediated transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,231,6,2.6,no,,,,, P101,21,B9,P101_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL042C-A,,YAL043C-A,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF ERV46/YAL042W; YAL042C-A is a non-essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,14,5.7,no,,,,, P101,22,B10,P101_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL040C,CLN3,WHI1;FUN10;DAF1,"G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis","vacuole organization, transcription, cell cycle, cellular membrane organization, RNA metabolic process",enzyme regulator activity,nucleus,"cell cycle, enzyme regulator activity, membrane organization and biogenesis, nucleus, organelle organization and biogenesis, other",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,20,7.5,no,,,,, P101,23,B11,P101_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL037W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,250,18,7.2,no,,,,, P101,24,B12,P101_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL036C,RBG1,FUN11,"Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts with Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid",biological_process,other,cytoplasm,"cytoplasm, other, ribosome biogenesis",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,234,10,4.3,no,,,,, P101,25,C1,P101_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL035W,FUN12,eIF5B;yIF2,"GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2",translation,"RNA binding, hydrolase activity","ribosome, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, ribosome, translation, translation regulator activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,16,5.1,no,,,,, P101,26,C2,P101_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL034C,FUN19,,Non-essential protein of unknown function; expression induced in response to heat stress,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,2,1,no,,,,, P101,27,C3,P101_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL031C,GIP4,FUN21,Cytoplasmic Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate,chromosome segregation,"protein binding, enzyme regulator activity",cytoplasm,"cytoplasm, enzyme regulator activity, other, protein binding",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,10,3,no,,,,, P101,28,C4,P101_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL030W,SNC1,,Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins,"transport, vesicle organization, vesicle-mediated transport, cellular membrane organization",protein binding,"cellular bud, cytoplasmic membrane-bounded vesicle, membrane, site of polarized growth, Golgi apparatus, cytoplasm, plasma membrane","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,5,2.4,no,,,,, P101,29,C5,P101_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL029C,MYO4,SHE1;FUN22,"One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p",DNA metabolic process,"motor activity, hydrolase activity, protein binding","cytoskeleton, mitochondrion, cellular bud, site of polarized growth, cytoplasm","DNA metabolic process, cellular bud, cytoskeleton, mitochondrion, motor activity, organelle organization and biogenesis, other, protein binding",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,267,7,2.6,no,,,,, P101,30,C6,P101_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL028W,FRT2,HPH2,"Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate",response to stress,molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, response to stress",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,12,6.2,no,,,,, P101,31,C7,P101_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL026C,DRS2,SWA3;FUN38,Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease,"transport, vesicle-mediated transport, ribosome biogenesis, cellular membrane organization","transporter activity, hydrolase activity","cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, hydrolase activity, membrane organization and biogenesis, organelle organization and biogenesis, ribosome biogenesis, transport, transporter activity, vesicle-mediated transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,25,10.9,no,,,,, P101,32,C8,P101_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL023C,PMT2,FUN25,"Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals","cellular carbohydrate metabolic process, protein modification process",transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, protein modification process, transferase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,8,2.8,no,,,,, P101,33,C9,P101_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL022C,FUN26,,Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes,transport,transporter activity,membrane,"membrane, other, transport, transporter activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,290,72,24.8,no,,,,, P101,34,C10,P101_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL021C,CCR4,NUT21;FUN27,"Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening","signaling process, transcription, cell cycle, DNA metabolic process, RNA metabolic process",hydrolase activity,"nucleus, cytoplasm","DNA metabolic process, RNA metabolic process, cell cycle, cytoplasm, hydrolase activity, nucleus, response to chemical stimulus, transcription",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,264,10,3.8,no,,,,, P101,35,C11,P101_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL020C,ATS1,KTI13;FUN28,"Protein required, with Elongator complex, Kti11p, and Kti12p, for modification of wobble nucleosides in tRNA; has a potential role in regulatory interactions between microtubules and the cell cycle","cell budding, cytoskeleton organization, RNA metabolic process",molecular_function,cytoplasm,"RNA metabolic process, cell budding, cytoplasm, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,318,34,10.7,no,,,,, P101,36,C12,P101_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL019W,FUN30,,"Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","chromosome organization, transcription, RNA metabolic process",molecular_function,"nucleus, chromosome, mitochondrion, cytoplasm","mitochondrion, molecular_function, nucleus, organelle organization and biogenesis",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,284,36,12.7,no,,,,, P101,37,D1,P101_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL018C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,241,12,5,no,,,,, P101,38,D2,P101_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL017W,PSK1,FUN31,One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status,"cellular carbohydrate metabolic process, generation of precursor metabolites and energy, protein modification process","transferase activity, protein kinase activity",cytoplasm,"carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, protein kinase activity, protein modification process, transferase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,12,5.4,no,,,,, P101,39,D3,P101_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL015C,NTG1,SCR1;FUN33,DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress,"mitochondrion organization, response to chemical stimulus, response to stress, DNA metabolic process","hydrolase activity, lyase activity","nucleus, mitochondrion, cytoplasm","DNA metabolic process, hydrolase activity, lyase activity, mitochondrion, nucleus, response to stress",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,6,1.8,no,,,,, P101,40,D4,P101_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL014C,SYN8,SLT2;UIP2,Endosomal SNARE related to mammalian syntaxin 8,transport,protein binding,cytoplasm,"cytoplasm, protein binding, transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,6,3,no,,,,, P101,41,D5,P101_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL013W,DEP1,FUN54,"Transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation","transcription, protein modification process, cellular lipid metabolic process, chromosome organization, DNA metabolic process, RNA metabolic process","transcription regulator activity, hydrolase activity","nucleus, chromosome","RNA metabolic process, hydrolase activity, lipid metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transcription regulator activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,8,4,no,,,,, P101,42,D6,P101_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL011W,SWC3,SWC1,"Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae",chromosome organization,molecular_function,"nucleus, chromosome, mitochondrion, cytoplasm","mitochondrion, molecular_function, nucleus, organelle organization and biogenesis, response to chemical stimulus",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,6,3.5,no,,,,, P101,43,D7,P101_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL010C,MDM10,FUN37,"Subunit of both the ERMES complex that links the ER to mitochondria, and of the mitochondrial sorting and assembly machinery (SAM complex) that functions in import and assembly of outer membrane beta-barrel proteins","transport, mitochondrion organization, protein complex biogenesis, cellular membrane organization",molecular_function,"endomembrane system, mitochondrion, membrane, mitochondrial envelope, endoplasmic reticulum, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, other, transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,20,10,no,,,,, P101,44,D8,P101_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL009W,SPO7,,"Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation","meiosis, sporulation resulting in formation of a cellular spore, cellular lipid metabolic process, cell cycle, nucleus organization, cellular membrane organization","hydrolase activity, phosphoprotein phosphatase activity","endomembrane system, membrane","endomembrane system, meiosis, membrane, nuclear organization and biogenesis, phosphoprotein phosphatase activity, sporulation",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,9,5,no,,,,, P101,45,D9,P101_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL008W,FUN14,,Mitochondrial protein of unknown function,biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,11,6.3,no,,,,, P101,46,D10,P101_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL007C,ERP2,,"Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles","transport, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, transport, vesicle-mediated transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,30,13.6,no,,,,, P101,47,D11,P101_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL004W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene SSA1/YAL005C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,20,8.7,no,,,,, P101,48,D12,P101_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL005C,SSA1,YG100,"ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall","transport, mitochondrion organization, translation, response to stress, protein folding","hydrolase activity, protein binding","nucleus, membrane fraction, vacuole, cell wall, membrane, cytoplasm","cell wall, cytoplasm, hydrolase activity, membrane, nucleus, organelle organization and biogenesis, protein binding, protein folding, response to stress, translation, transport, vacuole",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,170,6,3.5,no,,,,, P101,49,E1,P101_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL002W,VPS8,VPL8;VPT8;FUN15,Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif,"transport, vesicle-mediated transport",molecular_function,"membrane fraction, cytoplasm","cytoplasm, membrane fraction, molecular_function, transport, vesicle-mediated transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,2,1.1,no,,,,, P101,50,E2,P101_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR002W,NUP60,,"Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance","transport, protein complex biogenesis",structural molecule activity,"nucleus, membrane, endomembrane system","endomembrane system, membrane, nucleus, structural molecule activity, transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,180,44,24.4,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P101,51,E3,P101_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR003W,SWD1,SAF49;CPS50;FUN16,"Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7","chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process",transferase activity,nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transferase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,2,1.1,no,,,,, P101,52,E4,P101_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR014C,BUD14,,"Protein involved in bud-site selection, Bud14p-Glc7p complex is a cortical regulator of dynein; inhibitor of the actin assembly factor Bnr1p (formin); diploid mutants display a random budding pattern instead of the wild-type bipolar pattern","cytoskeleton organization, transcription, protein complex biogenesis, RNA metabolic process",enzyme regulator activity,"cellular bud, site of polarized growth","RNA metabolic process, anatomical structure morphogenesis, cellular bud, cytoskeleton organization and biogenesis, enzyme regulator activity, other, site of polarized growth, transcription",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,3,1.6,no,,,,, P101,53,E5,P101_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR015W,ADE1,,"N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine",heterocycle metabolic process,ligase activity,"nucleus, cytoplasm","cytoplasm, ligase activity, nucleus, other, response to chemical stimulus",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,4,2.1,no,,,,, P101,54,E6,P101_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR018C,KIN3,NPK1;FUN52,Nonessential protein kinase with unknown cellular role,chromosome segregation,"transferase activity, protein kinase activity",cellular_component,"cellular_component, other, protein kinase activity",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,9,3.9,no,,,,, P101,55,E7,P101_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR020C,PAU7,,"Member of the seripauperin multigene family, active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,5,2.5,no,,,,, P101,56,E8,P101_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR023C,,,"Putative integral membrane protein, member of DUP240 gene family",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,5,2.6,no,,,,, P101,57,E9,P101_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR027W,UIP3,,Putative integral membrane protein of unknown function; interacts with Ulp1p at the nuclear periphery; member of DUP240 gene family,biological_process,molecular_function,"nucleus, endomembrane system","biological_process, endomembrane system, molecular_function, nucleus",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,8,4.7,no,,,,, P101,58,E10,P101_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR028W,,,"Putative integral membrane protein, member of DUP240 gene family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,12,5.3,no,,,,, P101,59,E11,P101_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR029W,,,Member of DUP240 gene family but contains no transmembrane domains; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,242,24,9.9,no,,,,, P101,60,E12,P101_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR031W,PRM9,,"Pheromone-regulated protein with 3 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; member of DUP240 gene family",vesicle organization,molecular_function,"membrane, endoplasmic reticulum, plasma membrane, cytoplasm","endoplasmic reticulum, membrane, molecular_function, organelle organization and biogenesis, plasma membrane, response to chemical stimulus",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,224,14,6.3,no,,,,, P101,61,F1,P101_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR030C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YAR029W and the verified gene PRM9",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,0,0,no,,,,, P101,62,F2,P101_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR035W,YAT1,,"Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated","cellular amino acid and derivative metabolic process, vitamin metabolic process",transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, other, transferase activity, vitamin metabolic process",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,5,2.7,no,,,,, P101,63,F3,P101_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR037W,,,,,,,,,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P101,64,F4,P101_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR040C,,,,,,,,,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P101,65,F5,P101_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR042W,SWH1,OSH1;YAR044W,Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction,"transport, vesicle-mediated transport, cellular membrane organization","lipid binding, transporter activity","nucleus, endomembrane system, endoplasmic reticulum, Golgi apparatus, cytoplasm","Golgi apparatus, anatomical structure morphogenesis, cytoplasm, endomembrane system, endoplasmic reticulum, lipid binding, membrane organization and biogenesis, nucleus, transport, vesicle-mediated transport",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,5,2.1,no,,,,, P101,66,F6,P101_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR043C-a,,,,,,,,,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P101,67,F7,P101_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR044W,,,,,,,,,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P101,68,F8,P101_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAR047C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,01_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,267,6,2.2,no,,,,, P101,69,F9,P101_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL001W,DNM1,,Dynamin-related GTPase required for mitochondrial fission and morphology; assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis and regulating peroxisome abundance,"mitochondrion organization, peroxisome organization, protein complex biogenesis","hydrolase activity, protein binding","peroxisome, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, protein binding",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,4,1.2,no,,,,, P101,70,F10,P101_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL002W,RTT109,KAT11;REM50;KIM2,Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase; acetylates H3-K56 and H3-K9; involved in non-homologous end joining and in regulation of Ty1 transposition; interacts physically with Vps75p,"transcription, transposition, protein modification process, response to stress, chromosome organization, DNA metabolic process, RNA metabolic process",transferase activity,nucleus,"DNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, response to stress, transferase activity, transposition",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,294,158,53.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P101,71,F11,P101_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL005C,SPO75,,"Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,cellular_component,"cell wall organization and biogenesis, cellular_component, molecular_function, sporulation",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,182,9,4.9,no,,,,, P101,72,F12,P101_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL010C,PSR1,,"Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p",response to stress,"phosphoprotein phosphatase activity, hydrolase activity","membrane, plasma membrane","phosphoprotein phosphatase activity, plasma membrane, response to stress",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,222,9,4.1,no,,,,, P101,73,G1,P101_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL012W,YEH1,,"Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes",other,hydrolase activity,"membrane, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, membrane",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,7,3.4,no,,,,, P101,74,G2,P101_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL013C,PUF3,,"Protein of the mitochondrial outer surface, links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins","mitochondrion organization, generation of precursor metabolites and energy, cellular respiration, RNA metabolic process",RNA binding,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","RNA binding, RNA metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,9,4.1,no,,,,, P101,75,G3,P101_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL014W,EMC6,,Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response,protein folding,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,10,5.5,no,,,,, P101,76,G4,P101_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL015W,BPT1,,"ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p",transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,0,0,no,,,,, P101,77,G5,P101_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL016W,,,,,,,,,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,1,0.5,no,,,,, P101,78,G6,P101_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL017W,,,,,,,,,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,21,11.1,no,,,,, P101,79,G7,P101_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL019C,KNS1,L124,"Nonessential putative protein kinase of unknown cellular role; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues",protein modification process,"transferase activity, protein kinase activity",cellular_component,"cellular_component, protein kinase activity, protein modification process, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,10,4.7,no,,,,, P101,80,G8,P101_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL020C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene KNS1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,8,3.9,no,,,,, P101,81,G9,P101_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL021W,SPA2,PEA1;FUS6,"Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate","cell budding, signaling process, cytoskeleton organization, cytokinesis, response to chemical stimulus, conjugation, pseudohyphal growth, cellular component morphogenesis, cell cycle",protein binding,"cell cortex, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, conjugation, cytokinesis, cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding, pseudohyphal growth, response to chemical stimulus, signal transduction, site of polarized growth",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,8,3.2,no,,,,, P101,82,G10,P101_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL023C,POM33,,"Transmembrane nucleoporin involved in nuclear pore complex (NPC) distribution, assembly or stabilization; highly conserved across species, orthologous to human TMEM33 and paralogous to Per33p",nucleus organization,molecular_function,"nucleus, endomembrane system, ribosome, membrane, endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function, ribosome",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,222,18,8.1,no,,,,, P101,83,G11,P101_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL024C,SSA2,YG102,"ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall","transport, response to stress, protein folding","hydrolase activity, protein binding","membrane fraction, vacuole, mitochondrion, cell wall, membrane, cytoplasm","cell wall, cytoplasm, hydrolase activity, membrane, mitochondrion, other, protein binding, protein folding, response to stress, transport, vacuole",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,342,25,7.3,no,,,,, P101,84,G12,P101_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL025W,PAU17,,"Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions; YLL025W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,175,7,4,no,,,,, P101,85,H1,P101_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL026W,HSP104,,"Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation","response to stress, cellular carbohydrate metabolic process, protein folding, response to chemical stimulus","protein binding, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, protein binding, protein folding, response to stress",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,23,12.5,no,,,,, P101,86,H2,P101_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL028W,TPO1,,"Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane",transport,transporter activity,"cellular bud, membrane, vacuole, plasma membrane, cytoplasm","cellular bud, cytoplasm, membrane, plasma membrane, transport, transporter activity, vacuole",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,20,11.5,no,,,,, P101,87,H3,P101_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P101,88,H4,P101_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL029W,FRA1,RUP2,"Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation","transcription, response to chemical stimulus, RNA metabolic process",molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, response to chemical stimulus, transcription",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,6,2.9,no,,,,, P101,89,H5,P101_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL032C,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,4,1.8,no,,,,, P101,90,H6,P101_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL038C,ENT4,,"Protein of unknown function, contains an N-terminal epsin-like domain; proposed to be involved in the trafficking of Arn1p in the absence of ferrichrome","transport, cytoskeleton organization, vesicle-mediated transport, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,13,7.2,no,,,,, P101,91,H7,P101_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL039C,UBI4,UB14;SCD2,"Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats","response to stress, sporulation resulting in formation of a cellular spore, protein modification process",protein binding,cytoplasm,"cytoplasm, other, protein binding, protein modification process, response to stress, sporulation",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,4,1.5,no,,,,, P101,92,H8,P101_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL040C,VPS13,VPT2;SOI1,"Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention","transport, sporulation resulting in formation of a cellular spore, vesicle-mediated transport, cellular protein catabolic process",molecular_function,"mitochondrion, membrane, cytoplasm","cytoplasm, membrane, mitochondrion, molecular_function, other, protein catabolic process, sporulation, transport, vesicle-mediated transport",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,2,0.9,no,,,,, P101,93,H9,P101_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL041C,SDH2,SDHB;ACN17,"Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,277,2,0.7,no,,,,, P101,94,H10,P101_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL043W,FPS1,,"Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress","transport, response to chemical stimulus, conjugation",transporter activity,"vacuole, membrane, cytoplasm, plasma membrane","conjugation, cytoplasm, plasma membrane, response to chemical stimulus, transport, transporter activity, vacuole",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,284,6,2.1,no,,,,, P101,95,H11,P101_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL045C,RPL8B,rp6;YL5;L8B;L4B;SCL41;KRB1,"Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,262,22,8.4,no,,,,, P101,96,H12,P101_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL046C,RNP1,,Ribonucleoprotein that contains two RNA recognition motifs (RRM),ribosome biogenesis,RNA binding,cytoplasm,"RNA binding, cytoplasm, ribosome biogenesis",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,175,4,2.3,no,,,,, P102,1,A1,P102_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL047W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene RNP1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,4,1.6,no,,,,, P102,2,A2,P102_A2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P102,3,A3,P102_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL051C,FRE6,,Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels,"transport, cellular homeostasis",oxidoreductase activity,"membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, membrane, oxidoreductase activity, transport, vacuole",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,36,15.9,no,,,,, P102,4,A4,P102_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL052C,AQY2,,"Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains",transport,transporter activity,"membrane, endomembrane system, endoplasmic reticulum, plasma membrane, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, plasma membrane, transport, transporter activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,6,2.9,no,,,,, P102,5,A5,P102_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL053C,,,Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,6,2.5,no,,,,, P102,6,A6,P102_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL054C,,,"Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene",biological_process,"transcription regulator activity, DNA binding","membrane, plasma membrane","biological_process, plasma membrane, transcription regulator activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,13,6.2,no,,,,, P102,7,A7,P102_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL055W,YCT1,,High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene,transport,transporter activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, transport, transporter activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,26,12,no,,,,, P102,8,A8,P102_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL056C,,,"Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p and genes involved in pleiotropic drug resistance (PDR); expression is induced in cells treated with the mycotoxin patulin",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,211,10,4.7,no,,,,, P102,9,A9,P102_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL057C,JLP1,,"Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase, involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation",other,oxidoreductase activity,cellular_component,"cellular_component, other, oxidoreductase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,7,4,no,,,,, P102,10,A10,P102_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL058W,,,"Putative protein of unknown function with similarity to Str2p, which is a cystathionine gamma-synthase important in sulfur metabolism; YLL058W is not an essential gene",other,transferase activity,cellular_component,"cellular_component, other, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,270,10,3.7,no,,,,, P102,11,A11,P102_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL060C,GTT2,,"Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p","cofactor metabolic process, cellular amino acid and derivative metabolic process",transferase activity,"mitochondrion, cytoplasm","cofactor metabolic process, mitochondrion, response to chemical stimulus, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,14,6.5,no,,,,, P102,12,A12,P102_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL061W,MMP1,,"High-affinity S-methylmethionine permease, required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,16,7.8,no,,,,, P102,13,B1,P102_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL062C,MHT1,,"S-methylmethionine-homocysteine methyltransferase, functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio",cellular amino acid and derivative metabolic process,transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,17,8.6,no,,,,, P102,14,B2,P102_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL063C,AYT1,,"Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis",other,transferase activity,cellular_component,"cellular_component, other, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,23,11.7,no,,,,, P102,15,B3,P102_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR001C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated",biological_process,molecular_function,"membrane, vacuole, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrion, molecular_function, vacuole",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,12,4.9,no,,,,, P102,16,B4,P102_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR003C,CMS1,,Subunit of U3-containing 90S preribosome processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit; overexpression rescues supressor mutant of mcm10; null mutant is viable,ribosome biogenesis,molecular_function,nucleus,"DNA metabolic process, cytoplasm, molecular_function, nucleolus, nucleus, ribosome biogenesis",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,10,3.1,no,,,,, P102,17,B5,P102_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR004C,THI73,,Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs,transport,transporter activity,"membrane, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, membrane, transport, transporter activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,12,4.9,no,,,,, P102,18,B6,P102_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR011W,LOT6,,"FMN-dependent NAD(P)H:quinone reductase, may be involved in quinone detoxification; expression elevated at low temperature; sequesters the Cin5p transcription factor in the cytoplasm in complex with the proteasome under reducing conditions","transport, response to stress, response to chemical stimulus","protein binding, oxidoreductase activity","nucleus, cytoplasm","cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,9,5,no,,,,, P102,19,B7,P102_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR012C,,,Putative protein of unknown function; YLR012C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,238,6,2.5,no,,,,, P102,20,B8,P102_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR013W,GAT3,,Protein containing GATA family zinc finger motifs,transcription,DNA binding,nucleus,"DNA binding, nucleus, transcription, transcription regulator activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,1,0.4,no,,,,, P102,21,B9,P102_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR014C,PPR1,,"Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p","transcription, heterocycle metabolic process, cellular aromatic compound metabolic process, RNA metabolic process",other,nucleus,"DNA binding, RNA metabolic process, aromatic compound metabolic process, heterocycle metabolic process, nucleus, transcription, transcription regulator activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,267,1,0.4,no,,,,, P102,22,B10,P102_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR015W,BRE2,CPS60,"Subunit of COMPASS (Set1C) complex, which methylates Lys4 of histone H3 and functions in silencing at telomeres; has a C-terminal Sdc1 Dpy-30 Interaction (SDI) domain that mediates binding to Sdc1p; similar to trithorax-group protein ASH2L","chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process","transcription regulator activity, transferase activity",nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transcription regulator activity, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,9,4.8,no,,,,, P102,23,B11,P102_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR016C,PML1,,"Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p","transport, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, nucleus, transport",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,250,3,1.2,no,,,,, P102,24,B12,P102_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR017W,MEU1,,"Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression",cellular amino acid and derivative metabolic process,transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,205,5,2.4,no,,,,, P102,25,C1,P102_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR018C,POM34,,Integral membrane protein of the nuclear pore; has an important role in maintaining the architecture of the pore complex,"transport, nucleus organization",molecular_function,"nucleus, membrane, endomembrane system","endomembrane system, membrane, molecular_function, nucleus, transport",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,1,0.6,no,,,,, P102,26,C2,P102_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR019W,PSR2,,"Functionally redundant Psr1p homolog, a plasma membrane phosphatase involved in the general stress response; required with Psr1p and Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p",response to stress,"phosphoprotein phosphatase activity, hydrolase activity","membrane, plasma membrane","phosphoprotein phosphatase activity, plasma membrane, response to stress",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,12,4.7,no,,,,, P102,27,C3,P102_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR020C,YEH2,,"Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism",other,hydrolase activity,"membrane, plasma membrane","cell wall organization and biogenesis, hydrolase activity, lipid metabolic process, membrane, plasma membrane",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,14,8.2,no,,,,, P102,28,C4,P102_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR021W,IRC25,DMP2;PBA3;POC3,Component of a heterodimeric Poc4p-Irc25p chaperone involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions,"protein complex biogenesis, RNA metabolic process",molecular_function,other,"molecular_function, other",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,52,19.4,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P102,29,C5,P102_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR023C,IZH3,,"Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity",cellular homeostasis,other,"membrane, endoplasmic reticulum, cytoplasm","cellular homeostasis, endoplasmic reticulum, membrane, other",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,21,10.5,no,,,,, P102,30,C6,P102_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR024C,UBR2,,Cytoplasmic ubiquitin-protein ligase (E3); required for ubiquitylation of Rpn4p; mediates formation of a Mub1p-Ubr2p-Rad6p complex,protein modification process,ligase activity,cytoplasm,"cytoplasm, ligase activity, protein modification process",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,47,19.6,no,,,,, P102,31,C7,P102_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR025W,SNF7,VPL5;RNS4;VPS32;DID1,One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes,"transport, vesicle organization, response to chemical stimulus, response to stress, vesicle-mediated transport, cellular membrane organization, cellular protein catabolic process",protein binding,"membrane, cytoplasm","cytoplasm, membrane, protein binding, protein catabolic process, transport, vesicle-mediated transport",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,14,6.1,no,,,,, P102,32,C8,P102_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR028C,ADE16,,"Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine","sporulation resulting in formation of a cellular spore, heterocycle metabolic process, generation of precursor metabolites and energy, cellular respiration","transferase activity, hydrolase activity",cytoplasm,"cellular respiration, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, other, sporulation, transferase activity",,,12_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,202,1,0.5,no,,,,, P102,33,C9,P102_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR042C,,,Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene,biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,211,9,4.3,no,,,,, P102,34,C10,P102_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR043C,TRX1,LMA1,"Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance","vacuole organization, transport, response to chemical stimulus, protein modification process, response to stress, vesicle-mediated transport, DNA metabolic process, cellular homeostasis, cellular membrane organization",oxidoreductase activity,"vacuole, cytoplasm","DNA metabolic process, cellular homeostasis, cytoplasm, membrane organization and biogenesis, organelle organization and biogenesis, other, oxidoreductase activity, response to chemical stimulus, response to stress, transport, vacuole, vesicle-mediated transport",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,181,12,6.6,no,,,,, P102,35,C11,P102_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR044C,PDC1,,"Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism","cellular amino acid and derivative metabolic process, heterocycle metabolic process, generation of precursor metabolites and energy, cellular aromatic compound metabolic process, cellular carbohydrate metabolic process",lyase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, generation of precursor metabolites and energy, heterocycle metabolic process, lyase activity, nucleus, other",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,328,10,3,no,,,,, P102,36,C12,P102_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR046C,,RLA1,Putative membrane protein; member of the fungal lipid-translocating exporter (LTE) family of proteins; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,5,2.3,no,,,,, P102,37,D1,P102_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR047C,FRE8,,"Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p",cellular homeostasis,oxidoreductase activity,membrane,"cellular homeostasis, membrane, oxidoreductase activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,34,10.1,no,,,,, P102,38,D2,P102_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR048W,RPS0B,S0B;YST2;NAB1B,"Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal","transport, translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,5,2.2,no,,,,, P102,39,D3,P102_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR049C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,4,1.6,no,,,,, P102,40,D4,P102_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR053C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,36,10.9,no,,,,, P102,41,D5,P102_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR054C,OSW2,,Protein of unknown function proposed to be involved in the assembly of the spore wall,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,"membrane, cytoplasm","cell wall organization and biogenesis, cytoplasm, membrane, molecular_function, sporulation",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,287,31,10.8,no,,,,, P102,42,D6,P102_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR055C,SPT8,,"Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters","chromosome organization, transcription, protein modification process, RNA metabolic process","transcription regulator activity, protein binding",nucleus,"RNA metabolic process, nucleus, protein binding, transcription, transcription regulator activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,479,39,8.1,no,,,,, P102,43,D7,P102_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR056W,ERG3,PSO6;SYR1,"C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources",other,oxidoreductase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, membrane organization and biogenesis, oxidoreductase activity, transport, vesicle-mediated transport",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,6,2.9,no,,,,, P102,44,D8,P102_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR057W,,,Putative protein of unknown function; YLR050W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,274,8,2.9,no,,,,, P102,45,D9,P102_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR058C,SHM2,SHMT2,"Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis",other,transferase activity,"site of polarized growth, membrane fraction, cytoplasm","cytoplasm, other, transferase activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,2,1,no,,,,, P102,46,D10,P102_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR059C,REX2,YNT20,"3'-5' RNA exonuclease; involved in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and RNase P and RNase MRP RNA; localized to mitochondria and null suppresses escape of mtDNA to nucleus in yme1 yme2 mutants; RNase D exonuclease","mitochondrion organization, ribosome biogenesis, RNA metabolic process",hydrolase activity,"mitochondrion, cytoplasm","RNA metabolic process, hydrolase activity, mitochondrion, organelle organization and biogenesis, ribosome biogenesis",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,225,9,4,no,,,,, P102,47,D11,P102_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR061W,RPL22A,rp4;l1c;YL31;L22A,"Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Bp and to rat L22 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,224,1,0.4,no,,,,, P102,48,D12,P102_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR062C,BUD28,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene RPL22A; diploid mutant displays a weak budding pattern phenotype in a systematic assay","cytokinesis, cell cycle",molecular_function,cellular_component,"anatomical structure morphogenesis, cellular_component, cytokinesis, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,201,4,2,no,,,,, P102,49,E1,P102_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR063W,,,Putative S-adenosylmethionine-dependent methyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR063W is not an essential gene,biological_process,transferase activity,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,6,3,no,,,,, P102,50,E2,P102_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR064W,PER33,,"Putative protein of unknown function; localizes to the endoplasmic reticulum with some nuclear pore complex association; highly conserved across species, orthologous to human TMEM33 and paralogous to Per33p; YLR064W is not an essential gene",biological_process,molecular_function,"nucleus, membrane, endomembrane system, endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,52,16,no,,,,, P102,51,E3,P102_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR065C,,,Putative protein of unknown function; YLR065C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,17,9.4,no,,,,, P102,52,E4,P102_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR068W,FYV7,,Essential protein required for maturation of 18S rRNA; required for survival upon exposure to K1 killer toxin,"ribosome biogenesis, RNA metabolic process",molecular_function,"nucleus, nucleolus","RNA metabolic process, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,12,5.9,no,,,,, P102,53,E5,P102_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR072W,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YLR072W is not an esssential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,8,4.3,no,,,,, P102,54,E6,P102_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR073C,RFU1,,Protein that inhibits Doa4p deubiquitinating activity; contributes to ubiquitin homeostasis by regulating the conversion of free ubiquitin chains to ubiquitin monomers by Doa4p; GFP-fusion protein localizes to endosomes,cellular homeostasis,enzyme regulator activity,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,15,7.7,no,,,,, P102,55,E7,P102_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR074C,BUD20,,Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern,"cytokinesis, cell cycle",molecular_function,nucleus,"anatomical structure morphogenesis, cytokinesis, molecular_function, nucleus, ribosome biogenesis",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,194,6,3.1,no,,,,, P102,56,E8,P102_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR077W,FMP25,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,309,4,1.3,no,,,,, P102,57,E9,P102_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR079W,SIC1,SDB25,"Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1","response to stress, cell cycle",enzyme regulator activity,"nucleus, cytoplasm","DNA metabolic process, cell cycle, cytoplasm, enzyme regulator activity, nucleus, transposition",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,248,5,2,no,,,,, P102,58,E10,P102_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR080W,EMP46,,"Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport","transport, vesicle-mediated transport",protein binding,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, protein binding, transport, vesicle-mediated transport",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,194,5,2.6,no,,,,, P102,59,E11,P102_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR081W,GAL2,,"Galactose permease, required for utilization of galactose; also able to transport glucose","transport, cellular carbohydrate metabolic process",transporter activity,"membrane, plasma membrane","carbohydrate metabolic process, plasma membrane, transport, transporter activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,1,0.6,no,,,,, P102,60,E12,P102_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR082C,SRL2,,Protein of unknown function; overexpression suppresses the lethality caused by a rad53 null mutation,other,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, other",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,216,3,1.4,no,,,,, P102,61,F1,P102_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR083C,EMP70,TMN1;p24a,Protein with a role in cellular adhesion and filamentous growth; similar to Tmn2p and Tmn3p; member of Transmembrane Nine family of proteins with 9 transmembrane segments; 24kDa cleavage product found in endosome-enriched membrane fractions,"pseudohyphal growth, cellular homeostasis",molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, molecular_function, other, pseudohyphal growth",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,24,7.3,no,,,,, P102,62,F2,P102_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR084C,RAX2,,N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p,"cytokinesis, cell cycle",molecular_function,"cellular bud, cell wall, membrane, site of polarized growth, mitochondrion, cytoplasm","anatomical structure morphogenesis, cell wall, cellular bud, cytokinesis, membrane, mitochondrion, molecular_function, site of polarized growth",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,8,3.3,no,,,,, P102,63,F3,P102_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR085C,ARP6,,"Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A",chromosome organization,other,"nucleus, chromosome, cytoplasm","cytoplasm, nucleus, organelle organization and biogenesis, other",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,5,2.2,no,,,,, P102,64,F4,P102_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR087C,CSF1,,"Protein required for fermentation at low temperature; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",generation of precursor metabolites and energy,molecular_function,"mitochondrion, cytoplasm","generation of precursor metabolites and energy, mitochondrion, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,4,1.2,no,,,,, P102,65,F5,P102_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR089C,ALT1,,"Alanine transaminase (glutamic pyruvic transaminase); involved in alanine biosynthetic and catabolic processes; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",cellular amino acid and derivative metabolic process,transferase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, transferase activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,12,5.9,no,,,,, P102,66,F6,P102_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR090W,XDJ1,,"Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",protein folding,protein binding,"nucleus, membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, nucleus, other, protein folding",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,18,6.9,no,,,,, P102,67,F7,P102_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR092W,SUL2,,"High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates",transport,transporter activity,"membrane, membrane fraction, plasma membrane","plasma membrane, transport, transporter activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,185,6,3.2,no,,,,, P102,68,F8,P102_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR093C,NYV1,MAM2,v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane,"vacuole organization, transport, vesicle organization, vesicle-mediated transport, cellular membrane organization",protein binding,"vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vacuole, vesicle-mediated transport",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,233,13,5.6,no,,,,, P102,69,F9,P102_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR094C,GIS3,,Protein of unknown function,other,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, signal transduction",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,178,5,2.8,no,,,,, P102,70,F10,P102_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR095C,IOC2,,"Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif",chromosome organization,"DNA binding, protein binding, hydrolase activity",nucleus,"nucleus, organelle organization and biogenesis, protein binding",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,276,10,3.6,no,,,,, P102,71,F11,P102_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR096W,KIN2,,Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin1p,"transport, vesicle-mediated transport, protein modification process","transferase activity, protein kinase activity","membrane, plasma membrane","plasma membrane, protein kinase activity, protein modification process, transferase activity, transport, vesicle-mediated transport",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,4,2.1,no,,,,, P102,72,F12,P102_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR097C,HRT3,,"Putative SCF-ubiquitin ligase F-box protein, based on both genetic and physical interactions and sequence similarity; identified in association with Cdc53p, Skp1p and Ubi4 in large and small-scale studies","protein modification process, cellular protein catabolic process",ligase activity,other,"ligase activity, other, protein catabolic process, protein modification process",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,241,5,2.1,no,,,,, P102,73,G1,P102_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR098C,CHA4,SIL3;SIL2,"DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain","transcription, cellular amino acid and derivative metabolic process, RNA metabolic process",DNA binding,nucleus,"DNA binding, RNA metabolic process, amino acid and derivative metabolic process, nucleus, transcription, transcription regulator activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,14,6.5,no,,,,, P102,74,G2,P102_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR099C,ICT1,,"Lysophosphatidic acid acyltransferase, responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress",cellular lipid metabolic process,transferase activity,cellular_component,"cellular_component, lipid metabolic process, transferase activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,11,5.3,no,,,,, P102,75,G3,P102_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR102C,APC9,,"Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition","cytoskeleton organization, protein modification process, chromosome segregation, chromosome organization, cell cycle, cellular protein catabolic process","ligase activity, protein binding",nucleus,"cell cycle, cytoskeleton organization and biogenesis, ligase activity, nucleus, organelle organization and biogenesis, protein binding, protein catabolic process, protein modification process",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,21,11.9,no,,,,, P102,76,G4,P102_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR104W,LCL2,,Putative protein of unknown function; mutant is deficient in amounts of cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD),cellular protein catabolic process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,26,11.1,no,,,,, P102,77,G5,P102_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR107W,REX3,,RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases,"ribosome biogenesis, RNA metabolic process",hydrolase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, hydrolase activity, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,6,3.3,no,,,,, P102,78,G6,P102_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR108C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,4,1.6,no,,,,, P102,79,G7,P102_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR109W,AHP1,cTPxIII,"Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p","response to stress, cellular homeostasis, response to chemical stimulus",oxidoreductase activity,"membrane fraction, cytoplasm","cellular homeostasis, cytoplasm, oxidoreductase activity, response to chemical stimulus, response to stress",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,227,17,7.5,no,,,,, P102,80,G8,P102_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR111W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,2,1,no,,,,, P102,81,G9,P102_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR112W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,6,3.1,no,,,,, P102,82,G10,P102_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR113W,HOG1,SSK3,Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p,"transcription, response to chemical stimulus, protein modification process, response to stress, RNA metabolic process","transferase activity, protein kinase activity, signal transducer activity","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, protein kinase activity, protein modification process, response to chemical stimulus, response to stress, signal transducer activity, signal transduction, transcription, transferase activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,229,4,1.7,no,,,,, P102,83,G11,P102_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR114C,AVL9,,Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms,"transport, vesicle-mediated transport",molecular_function,cytoplasm,"cytoplasm, molecular_function, transport, vesicle-mediated transport",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,237,1,0.4,no,,,,, P102,84,G12,P102_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR118C,,APT1,Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS,biological_process,hydrolase activity,"nucleus, cytoplasm","biological_process, cytoplasm, hydrolase activity, nucleus",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,324,8,2.5,no,,,,, P102,85,H1,P102_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR119W,SRN2,VPL16;VPS37;SRN10,"Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; suppressor of rna1-1 mutation; may be involved in RNA export from nucleus","transport, cellular protein catabolic process",protein binding,"membrane, cytoplasm","cytoplasm, membrane, protein binding, protein catabolic process, transport",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,11,4.5,no,,,,, P102,86,H2,P102_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR120C,YPS1,YAP3,"Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor",fungal-type cell wall organization,"peptidase activity, hydrolase activity",cell wall,"cell wall, hydrolase activity, peptidase activity, protein modification process",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,12,4,no,,,,, P102,87,H3,P102_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P102,88,H4,P102_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR121C,YPS3,YPS4,"Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor",fungal-type cell wall organization,"peptidase activity, structural molecule activity, hydrolase activity","membrane, plasma membrane","cell wall organization and biogenesis, hydrolase activity, membrane, other, peptidase activity, plasma membrane, structural molecule activity",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,3,1.7,no,,,,, P102,89,H5,P102_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR122C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,3,1.3,no,,,,, P102,90,H6,P102_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR123C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,10,4.7,no,,,,, P102,91,H7,P102_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR124W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,221,0,0,no,,,,, P102,92,H8,P102_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR125W,,,Putative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P102,93,H9,P102_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YML089C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,13_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,211,16,7.6,no,,,,, P102,94,H10,P102_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YML088W,UFO1,,"F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation","response to stress, cellular protein catabolic process","protein binding, ligase activity","nucleus, cytoplasm","cytoplasm, ligase activity, nucleus, other, protein binding, protein catabolic process, response to stress",,,13_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,259,13,5,no,,,,, P102,95,H11,P102_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YML087C,AIM33,,"Putative protein of unknown function, highly conserved across species and orthologous to human CYB5R4; null mutant displays reduced frequency of mitochondrial genome loss",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,13_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,278,17,6.1,no,,,,, P102,96,H12,P102_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YML084W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,13_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,212,28,13.2,no,,,,, P105,1,A1,P105_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR289W,ABZ2,,"Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase), catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis","cofactor metabolic process, cellular amino acid and derivative metabolic process, vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",lyase activity,cytoplasm,"aromatic compound metabolic process, cofactor metabolic process, cytoplasm, heterocycle metabolic process, lyase activity, vitamin metabolic process",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,26,12.5,no,,,,, P105,2,A2,P105_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR291W,,,Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR291W is not an essential gene,biological_process,"transferase activity, protein kinase activity","nucleus, cytoplasm","biological_process, cytoplasm, nucleus, protein kinase activity",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,22,9.6,no,,,,, P105,3,A3,P105_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR292W,GOT1,,Homodimeric protein that is packaged into COPII vesicles and cycles between the ER and Golgi; involved in secretory transport but not directly required for aspects of transport assayed in vitro; may influence membrane composition,"transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, endoplasmic reticulum, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, membrane, molecular_function, transport, vesicle-mediated transport",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,260,16,6.2,no,,,,, P105,4,A4,P105_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR294W,JNM1,PAC3;INS1,"Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B","cytoskeleton organization, cell cycle",structural molecule activity,"cell cortex, cytoskeleton, microtubule organizing center, cytoplasm","cytoskeleton, other, structural molecule activity",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,218,8,3.7,no,,,,, P105,5,A5,P105_A5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P105,6,A6,P105_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR294W-A,,,"Dubious open reading frame unlikely to encode a functional protein, substantially overlaps YMR295C; deletion causes sensitivity to unfolded protein response-inducing agents",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,24,10.5,no,,,,, P105,7,A7,P105_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR295C,,,Protein of unknown function that associates with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud; YMR295C is not an essential gene,biological_process,molecular_function,"cellular bud, site of polarized growth, ribosome, cytoplasm","biological_process, cellular bud, molecular_function, ribosome",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,180,14,7.8,no,,,,, P105,8,A8,P105_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR297W,PRC1,CPY;LBC1,"Vacuolar carboxypeptidase Y (proteinase C; CPY), broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family",cellular protein catabolic process,"peptidase activity, hydrolase activity","vacuole, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, hydrolase activity, other, peptidase activity, protein catabolic process, transferase activity, vacuole",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,202,6,3,no,,,,, P105,9,A9,P105_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR299C,DYN3,,"Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration",transport,"motor activity, hydrolase activity","cytoskeleton, cytoplasm","cytoskeleton, cytoskeleton organization and biogenesis, motor activity, organelle organization and biogenesis, transport",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,234,2,0.9,no,,,,, P105,10,A10,P105_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR300C,ADE4,,"Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway",heterocycle metabolic process,transferase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, other, transferase activity",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,2,0.9,no,,,,, P105,11,A11,P105_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR302C,YME2,PRP12;RNA12,Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases,mitochondrion organization,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,238,22,9.2,no,,,,, P105,12,A12,P105_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR303C,ADH2,ADR2,"Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1","cofactor metabolic process, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, other, oxidoreductase activity, vitamin metabolic process",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,217,13,6,no,,,,, P105,13,B1,P105_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR304W,UBP15,,Ubiquitin-specific protease that may play a role in ubiquitin precursor processing,protein modification process,"peptidase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, peptidase activity, protein modification process",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,26,10,no,,,,, P105,14,B2,P105_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR304C-A,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SCW10",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,14,5.3,no,,,,, P105,15,B3,P105_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR305C,SCW10,,Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p,conjugation,hydrolase activity,"cell wall, extracellular region, endoplasmic reticulum, cytoplasm","cell wall, conjugation, cytoplasm, endoplasmic reticulum, hydrolase activity",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,28,12.4,no,,,,, P105,16,B4,P105_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR306C-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,22,12,no,,,,, P105,17,B5,P105_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR307W,GAS1,GGP1;CWH52,"Beta-1,3-glucanosyltransferase, required for cell wall assembly and also has a role in transcriptional silencing; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at the nuclear periphery","fungal-type cell wall organization, transcription, RNA metabolic process",transferase activity,"nucleus, membrane fraction, mitochondrion, cell wall, cytoplasmic membrane-bounded vesicle, membrane, cytoplasm, plasma membrane","Golgi apparatus, cell wall, cell wall organization and biogenesis, cytoplasm, cytoplasmic membrane-bounded vesicle, membrane fraction, mitochondrion, other, plasma membrane, transferase activity",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,26,9.3,no,,,,, P105,18,B6,P105_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR310C,,,Putative protein of unknown function; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR310C is not an essential gene,biological_process,molecular_function,nucleus,"molecular_function, nucleus, ribosome biogenesis",,,13_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,1,0.5,no,,,,, P105,19,B7,P105_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL339C,YRF1-6,YRF1,"Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p","chromosome organization, DNA metabolic process","helicase activity, hydrolase activity",nucleus,"DNA metabolic process, helicase activity, nucleus, organelle organization and biogenesis",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,10,3.1,no,,,,, P105,20,B8,P105_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL338W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps TEL14L-XC, which is Telomeric X element Core sequence on the left arm of Chromosome XIV",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,4,2.3,no,,,,, P105,21,B9,P105_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL336W,COS1,,"Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins",biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,3,1.7,no,,,,, P105,22,B10,P105_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL335W,DDI3,,Protein of unknown function; expression is induced over 100-fold by DNA damage; induction decreased in rad6 and rad18 mutants,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,1,0.5,no,,,,, P105,23,B11,P105_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL334C,SNO2,,"Protein of unknown function, nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin","vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",molecular_function,cellular_component,"cellular_component, molecular_function, vitamin metabolic process",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,1,0.6,no,,,,, P105,24,B12,P105_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL333W,SNZ2,,"Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p","vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",protein binding,cellular_component,"cellular_component, protein binding, vitamin metabolic process",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,6,3.2,no,,,,, P105,25,C1,P105_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL332W,THI12,,"Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13","vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",molecular_function,cellular_component,"cellular_component, molecular_function, vitamin metabolic process",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,5,2.8,no,,,,, P105,26,C2,P105_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL329C,PEX6,PAS8,AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol,"transport, signaling process, peroxisome organization","protein binding, hydrolase activity","peroxisome, membrane fraction, cytoplasm","cytoplasm, hydrolase activity, membrane fraction, organelle organization and biogenesis, other, peroxisome, protein binding, signal transduction, transport",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,14,4.4,no,,,,, P105,27,C3,P105_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL328C,MDJ2,,Constituent of the mitochondrial import motor associated with the presequence translocase; function overlaps with that of Pam18p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain,"transport, mitochondrion organization","enzyme regulator activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, enzyme regulator activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,251,6,2.4,no,,,,, P105,28,C4,P105_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL327W,EGT2,,"Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner",cytokinesis,hydrolase activity,"cellular bud, cell wall","cell wall, cellular bud, cytokinesis, hydrolase activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,2,1.1,no,,,,, P105,29,C5,P105_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL326C,PFA3,,"Palmitoyltransferase for Vac8p, required for vacuolar membrane fusion; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; autoacylates; required for vacuolar integrity under stress conditions","vacuole organization, protein modification process, cellular membrane organization",transferase activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein modification process, transferase activity, vacuole",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,8,2.8,no,,,,, P105,30,C6,P105_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL324W,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,304,4,1.3,no,,,,, P105,31,C7,P105_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL325C,FIG4,,"Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain",cellular lipid metabolic process,hydrolase activity,"membrane, vacuole, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, membrane, vacuole",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,20,9.6,no,,,,, P105,32,C8,P105_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL323W,LEM3,ROS3;BRE3,"Membrane protein of the plasma membrane and ER, interacts specifically in vivo with the phospholipid translocase (flippase) Dnf1p; involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane","transport, cellular membrane organization","hydrolase activity, transporter activity","membrane, endoplasmic reticulum, cytoplasm, plasma membrane","cytoplasm, endoplasmic reticulum, hydrolase activity, membrane, membrane organization and biogenesis, plasma membrane, signal transduction, transport, transporter activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,5,2.8,no,,,,, P105,33,C9,P105_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL322C,KRE1,,Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor,fungal-type cell wall organization,structural molecule activity,cell wall,"cell wall, cell wall organization and biogenesis, structural molecule activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,6,2.7,no,,,,, P105,34,C10,P105_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL321W,VNX1,,Calcium/H+ antiporter localized to the endoplasmic reticulum membrane; member of the calcium exchanger (CAX) family; potential Cdc28p substrate,transport,transporter activity,"membrane, endomembrane system, vacuole, endoplasmic reticulum, cytoplasm","cytoplasm, transport, transporter activity, vacuole",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,8,3.3,no,,,,, P105,35,C11,P105_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL320W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,3,1.6,no,,,,, P105,36,C12,P105_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL319W,,,Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene HXT14,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,0,0,no,,,,, P105,37,D1,P105_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL318C,HXT14,,"Protein with similarity to hexose transporter family members, expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, plasma membrane, transport, transporter activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,3,1.2,no,,,,, P105,38,D2,P105_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL314W,DAL82,,"Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain","transcription, heterocycle metabolic process, protein complex biogenesis, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, heterocycle metabolic process, nucleus, transcription, transcription regulator activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,390,0,0,no,,,,, P105,39,D3,P105_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL311C,,SKP2,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; putative F-box protein; analysis of integrated high-throughput datasets predicts involvement in ubiquitin-dependent protein catabolism",cellular protein catabolic process,protein binding,"ribosome, cytoplasm","other, protein binding, protein catabolic process, ribosome",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,1,0.5,no,,,,, P105,40,D4,P105_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL307C,MCK1,CMS1;YPK1,Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family,"protein modification process, chromosome segregation, response to stress, meiosis, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle, DNA metabolic process","transferase activity, protein kinase activity",other,"DNA metabolic process, cell cycle, meiosis, organelle organization and biogenesis, other, protein kinase activity, protein modification process, response to stress, sporulation, transferase activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,3,1.4,no,,,,, P105,41,D5,P105_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL305C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL305C is not an essential gene,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,18,5.3,no,,,,, P105,42,D6,P105_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL304W,YPT11,,Rab family GTPase that interacts with the C-terminal tail domain of Myo2p; mediates distribution of mitochondria and endoplasmic reticuli to daughter cells,mitochondrion organization,hydrolase activity,"cellular bud, site of polarized growth, endoplasmic reticulum, cytoplasm","cellular bud, hydrolase activity, organelle organization and biogenesis, other, site of polarized growth",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,2,0.8,no,,,,, P105,43,D7,P105_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL303W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,6,1.8,no,,,,, P105,44,D8,P105_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL302C,RPS19B,rp55B;YS16B;S19B;S16aB;RP55B,"Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap","transport, translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","RNA metabolic process, cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation, transport",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,5,2.7,no,,,,, P105,45,D9,P105_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL301C,RPL18B,rp28B;L18B;RP28B,"Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,243,0,0,no,,,,, P105,46,D10,P105_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL299W,TRF5,,"Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Pap2p",RNA metabolic process,"transferase activity, nucleotidyltransferase activity","nucleus, nucleolus","RNA metabolic process, cell cycle, nucleolus, nucleotidyltransferase activity, nucleus, organelle organization and biogenesis, transferase activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,354,7,2,no,,,,, P105,47,D11,P105_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL298W,CLA4,ERC10,"Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p","vacuole organization, response to chemical stimulus, protein modification process, cell cycle, transport, cell budding, signaling process, cytokinesis","protein kinase activity, transferase activity","nucleus, cell cortex, cytoskeleton, vacuole, cellular bud, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cell cycle, cytokinesis, cytoplasm, cytoskeleton, protein kinase activity, protein modification process, response to chemical stimulus, signal transduction, transferase activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,261,7,2.7,no,,,,, P105,48,D12,P105_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL296W,,,"Dubious open reading frame unlikely to encode a functional protein; deletion adversely affects sporulation; deletion mutant exhibits synthetic phenotype under expression of mutant huntingtin fragment, but gene does not have human ortholog","sporulation resulting in formation of a cellular spore, transcription, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, cellular_component, molecular_function, sporulation, transcription",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,30,9.1,no,,,,, P105,49,E1,P105_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL297C,MON2,YSL2,"Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p and localizes to the endosome; member of the Sec7p family of proteins","transport, vesicle-mediated transport, cellular membrane organization",enzyme regulator activity,"membrane, cytoplasm, Golgi apparatus","cytoplasm, enzyme regulator activity, membrane, membrane organization and biogenesis, transport, vesicle-mediated transport",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,3,1.4,no,,,,, P105,50,E2,P105_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL295W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,3,1.5,no,,,,, P105,51,E3,P105_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL294C,RIM21,PAL2,"Component of the RIM101 pathway, has a role in cell wall construction and alkaline pH response; has similarity to A. nidulans PalH",sporulation resulting in formation of a cellular spore,molecular_function,cellular_component,"cell wall organization and biogenesis, cellular_component, molecular_function, other, sporulation",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,0,0,no,,,,, P105,52,E4,P105_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL293W,MSB3,GYP3,"GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth","transport, cytoskeleton organization, vesicle-mediated transport",enzyme regulator activity,"cell cortex, cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, other, site of polarized growth, transport, vesicle-mediated transport",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,2,1,no,,,,, P105,53,E5,P105_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL292W,PUS4,,"Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)",RNA metabolic process,isomerase activity,"nucleus, mitochondrion, cytoplasm","RNA metabolic process, isomerase activity, mitochondrion, nucleus",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,1,0.5,no,,,,, P105,54,E6,P105_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL291C,MID1,,"N-glycosylated integral membrane protein of the ER membrane and plasma membrane, functions as a stretch-activated Ca2+-permeable cation channel required for Ca2+ influx stimulated by pheromone; interacts with Cch1p; forms an oligomer",transport,transporter activity,"membrane, endoplasmic reticulum, plasma membrane, cytoplasm","endoplasmic reticulum, plasma membrane, transport, transporter activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,2,1.2,no,,,,, P105,55,E7,P105_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL289W,PCL1,HCS26,"Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; localizes to sites of polarized cell growth","response to stress, cytoskeleton organization, cell cycle",enzyme regulator activity,nucleus,"anatomical structure morphogenesis, cell cycle, enzyme regulator activity, nucleus, other",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,0,0,no,,,,, P105,56,E8,P105_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL288W,CAF40,,"Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation, elongation and degradation; binds Cdc39p","transcription, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, transcription",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,4,2.1,no,,,,, P105,57,E9,P105_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL286W,CUS2,,"Protein that binds to U2 snRNA and Prp11p, may be involved in U2 snRNA folding; contains two RNA recognition motifs (RRMs)",RNA metabolic process,RNA binding,nucleus,"RNA binding, RNA metabolic process, nucleus",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,10,3,no,,,,, P105,58,E10,P105_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL285W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,4,1.3,no,,,,, P105,59,E11,P105_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL283C,WSC2,STA3,Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity and recovery from heat shock; secretory pathway Wsc2p is required for the arrest of secretion response,"fungal-type cell wall organization, signaling process, cytoskeleton organization, response to stress",signal transducer activity,"membrane fraction, cellular bud, site of polarized growth, cytoplasm","cell wall organization and biogenesis, cellular bud, cytoplasm, cytoskeleton organization and biogenesis, membrane fraction, organelle organization and biogenesis, response to stress, signal transducer activity, signal transduction, site of polarized growth",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,2,0.7,no,,,,, P105,60,E12,P105_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL281W,HCH1,,Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus,"response to stress, protein folding","protein binding, enzyme regulator activity","nucleus, cytoplasm","cytoplasm, enzyme regulator activity, nucleus, other, protein binding, protein folding, response to stress",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,13,6.5,no,,,,, P105,61,F1,P105_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL280C,ERG24,,"C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions",other,oxidoreductase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, oxidoreductase activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,1,0.5,no,,,,, P105,62,F2,P105_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL278W,CAF120,,"Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation","transcription, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, transcription",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,2,1,no,,,,, P105,63,F3,P105_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL275W,BOR1,,"Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1",transport,transporter activity,"membrane, membrane fraction, vacuole, plasma membrane, cytoplasm","cytoplasm, membrane fraction, other, plasma membrane, transport, transporter activity, vacuole",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,0,0,no,,,,, P105,64,F4,P105_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL273W,TOF1,,"Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase","signaling process, chromosome segregation, response to stress, chromosome organization, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, molecular_function, nucleus, organelle organization and biogenesis",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,2,0.6,no,,,,, P105,65,F5,P105_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL271C,BNI1,SHE5;PPF3,"Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1","cytoskeleton organization, cytokinesis, protein complex biogenesis, cell cycle",protein binding,"cell cortex, membrane fraction, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","DNA metabolic process, anatomical structure morphogenesis, cell budding, cell cortex, cell cycle, cellular bud, conjugation, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding, pseudohyphal growth, response to chemical stimulus, response to stress, signal transduction, site of polarized growth",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,8,3.1,no,,,,, P105,66,F6,P105_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL270C,ALP1,APL1,Arginine transporter; expression is normally very low and it is unclear what conditions would induce significant expression,transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,152,4,2.6,no,,,,, P105,67,F7,P105_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL269W,BSC4,,"Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough is increased upon depletion of Sup35p",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,2,1.1,no,,,,, P105,68,F8,P105_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL266W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF IST1/YNL265C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,2,0.9,no,,,,, P105,69,F9,P105_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL265C,IST1,,Protein with a positive role in the multivesicular body sorting pathway; functions and forms a complex with Did2p; recruitment to endosomes is mediated by the Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with Vps4p,"transport, vesicle-mediated transport",molecular_function,cytoplasm,"cytoplasm, molecular_function, translation, transport, vesicle-mediated transport",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,3,1.5,no,,,,, P105,70,F10,P105_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL264C,PDR17,SFH4;ISS1,"Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylcholine, found in the cytosol and microsomes, homologous to Pdr16p, deletion affects phospholipid composition","transport, cellular lipid metabolic process, response to chemical stimulus",transporter activity,cytoplasm,"cytoplasm, lipid metabolic process, response to chemical stimulus, transport, transporter activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,2,1,no,,,,, P105,71,F11,P105_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL259C,ATX1,,"Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake","transport, response to stress, cellular homeostasis, response to chemical stimulus",other,cytoplasm,"cellular homeostasis, cytoplasm, other, response to chemical stimulus, response to stress, transport",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,14,4.3,no,,,,, P105,72,F12,P105_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL257C,SIP3,,"Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate","transcription, RNA metabolic process","transcription regulator activity, protein binding",cellular_component,"RNA metabolic process, cellular_component, protein binding, transcription, transcription regulator activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,9,4.4,no,,,,, P105,73,G1,P105_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL255C,GIS2,,"Protein with seven cysteine-rich CCHC zinc-finger motifs, similar to human CNBP, proposed to be involved in the RAS/cAMP signaling pathway",other,molecular_function,cytoplasm,"cytoplasm, molecular_function, signal transduction",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,5,2.5,no,,,,, P105,74,G2,P105_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL254C,RTC4,,Protein of unknown function; null mutation suppresses cdc13-1 temperature sensitivity; (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,7,2.7,no,,,,, P105,75,G3,P105_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL253W,TEX1,,"Protein involved in mRNA export, component of the transcription export (TREX) complex",transport,molecular_function,nucleus,"molecular_function, nucleus, transport",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,2,0.9,no,,,,, P105,76,G4,P105_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL249C,MPA43,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,6,2,no,,,,, P105,77,G5,P105_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL248C,RPA49,A49,RNA polymerase I subunit A49,"transcription, RNA metabolic process",molecular_function,"nucleus, nucleolus","RNA metabolic process, nucleolus, nucleotidyltransferase activity, nucleus, other, ribosome biogenesis, transcription, transferase activity",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,6,2,no,,,,, P105,78,G6,P105_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL246W,VPS75,,"NAP family histone chaperone; binds to histones and Rtt109p, stimulating histone acetyltransferase activity; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting and in double-strand break repair","response to stress, chromosome organization, DNA metabolic process, protein modification process","protein binding, enzyme regulator activity","nucleus, chromosome","DNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, protein binding, protein modification process, response to stress",,,14_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,315,0,0,no,,,,, P105,79,G7,P105_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR001W,RRP6,,"Nuclear exosome exonuclease component; has 3'-5' exonuclease activity; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10)","ribosome biogenesis, chromosome organization, RNA metabolic process",hydrolase activity,"nucleus, nucleolus","RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, other, ribosome biogenesis",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,6,1.8,no,,,,, P105,80,G8,P105_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR002W,ALG6,,"Alpha 1,3 glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease","generation of precursor metabolites and energy, protein modification process, cellular respiration, cellular carbohydrate metabolic process, cellular lipid metabolic process",transferase activity,"endoplasmic reticulum, cytoplasm","carbohydrate metabolic process, cellular respiration, endoplasmic reticulum, generation of precursor metabolites and energy, lipid metabolic process, protein modification process, transferase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,18,10.6,no,,,,, P105,81,G9,P105_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR003W,YSP3,,Putative precursor to the subtilisin-like protease III,other,"peptidase activity, hydrolase activity",cellular_component,"cellular_component, peptidase activity, protein catabolic process",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,18,9.4,no,,,,, P105,82,G10,P105_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR005C,DNL4,LIG4,"DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth","response to stress, DNA metabolic process",ligase activity,"nucleus, chromosome","DNA metabolic process, chromosome, ligase activity, nucleus, other, response to stress",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,20,10.9,no,,,,, P105,83,G11,P105_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR006C,TSR3,,Protein required for correct processing of the 20S pre-rRNA at site D to generate mature 18S rRNA; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,"ribosome biogenesis, RNA metabolic process",molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,26,14.5,no,,,,, P105,84,G12,P105_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR007C,SGT2,,Glutamine-rich cytoplasmic protein that serves as a scaffold for binding Get4/5p and other proteins required to mediate posttranslational insertion of tail-anchored proteins into the ER membrane; has similarity to human cochaperone SGT,"transport, response to stress",molecular_function,cytoplasm,"cytoplasm, molecular_function, response to stress",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,28,14.3,no,,,,, P105,85,H1,P105_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR008C,SLG1,WSC1;HCS77,Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response,"cytoskeleton organization, peroxisome organization, fungal-type cell wall organization, transport, signaling process, response to stress, vesicle-mediated transport, cellular membrane organization",signal transducer activity,"cell cortex, membrane fraction, cytoskeleton, plasma membrane, cellular bud, membrane, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell cortex, cell wall organization and biogenesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane fraction, membrane organization and biogenesis, organelle organization and biogenesis, plasma membrane, response to stress, signal transducer activity, signal transduction, transport, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,12,6.7,no,,,,, P105,86,H2,P105_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR009W,TIR4,,Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock,biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,26,13.4,no,,,,, P105,87,H3,P105_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P105,88,H4,P105_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR010C,TIR2,SRP2,Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis,response to stress,molecular_function,cell wall,"cell wall, molecular_function, response to stress",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,16,5.3,no,,,,, P105,89,H5,P105_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR011W,AUS1,,"Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth",transport,"transporter activity, hydrolase activity","membrane, mitochondrion, cytoplasm","hydrolase activity, membrane, mitochondrion, transport, transporter activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,16,5.2,no,,,,, P105,90,H6,P105_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR012W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,21,9.8,no,,,,, P105,91,H7,P105_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR013W,IRC11,,"Dubious opening reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YOR012C; null mutant displays increased levels of spontaneous Rad52 foci",DNA metabolic process,molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,60,20.4,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P105,92,H8,P105_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR014W,RTS1,SCS1,B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A,"signaling process, protein modification process, chromosome segregation, meiosis, chromosome organization, cell cycle","hydrolase activity, phosphoprotein phosphatase activity","nucleus, cytoskeleton, microtubule organizing center, chromosome, cellular bud, site of polarized growth, cytoplasm","cell cycle, cellular bud, chromosome, cytoplasm, cytoskeleton, hydrolase activity, meiosis, microtubule organizing center, nucleus, organelle organization and biogenesis, other, phosphoprotein phosphatase activity, protein modification process, site of polarized growth, translation",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,20,6.1,no,,,,, P105,93,H9,P105_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR015W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,6,3,no,,,,, P105,94,H10,P105_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR016C,ERP4,,"Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport","transport, vesicle-mediated transport",molecular_function,membrane,"membrane, molecular_function, transport, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,24,14,no,,,,, P105,95,H11,P105_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR017W,PET127,,"Protein with a role in 5'-end processing of mitochondrial RNAs, located in the mitochondrial membrane",RNA metabolic process,molecular_function,"mitochondrial envelope, mitochondrion, cytoplasm","RNA metabolic process, mitochondrial envelope, mitochondrion, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,10,4.3,no,,,,, P105,96,H12,P105_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR018W,ROD1,ART4,"Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins","transport, vesicle-mediated transport, response to chemical stimulus, cellular membrane organization",protein binding,"membrane, plasma membrane","molecular_function, plasma membrane, response to chemical stimulus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,20,6.8,no,,,,, P106,1,A1,P106_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR019W,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments",other,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,32,12.3,no,,,,, P106,2,A2,P106_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR021C,,,Putative protein of unknown function; YOR021C is not an essential gene; predicted to be involved in rRNA processing and ribosome biogenesis and in biopolymer catabolism,biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, ribosome biogenesis",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,28,11.5,no,,,,, P106,3,A3,P106_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR022C,,,"Protein with similarity to bovine phospholipase A1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,hydrolase activity,"mitochondrion, cytoplasm","biological_process, hydrolase activity, mitochondrion",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,33,17.6,no,,,,, P106,4,A4,P106_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR023C,AHC1,,"Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex","chromosome organization, protein modification process",transferase activity,nucleus,"nucleus, organelle organization and biogenesis, protein modification process, transferase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,52,22.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P106,5,A5,P106_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR024W,,IRC12,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,46,20,no,,,,, P106,6,A6,P106_A6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P106,7,A7,P106_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR025W,HST3,,"Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism","cellular lipid metabolic process, chromosome organization, transcription, protein modification process, RNA metabolic process","DNA binding, hydrolase activity",nucleus,"DNA binding, RNA metabolic process, hydrolase activity, lipid metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,78,30,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P106,8,A8,P106_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR026W,BUB3,,"Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p","signaling process, cell cycle",molecular_function,"nucleus, chromosome","cell cycle, chromosome, molecular_function, nucleus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,294,32,10.9,no,,,,, P106,9,A9,P106_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR027W,STI1,,"Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein",protein folding,protein binding,cytoplasm,"cytoplasm, enzyme regulator activity, other, protein binding, protein folding",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,22,11.3,no,,,,, P106,10,A10,P106_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR028C,CIN5,YAP4;HAL6,"Basic leucine zipper (bZIP) transcription factor of the yAP-1 family, mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions","response to stress, transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","DNA binding, RNA metabolic process, nucleus, response to chemical stimulus, response to stress, transcription, transcription regulator activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,8,3.5,no,,,,, P106,11,A11,P106_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR029W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,12,4,no,,,,, P106,12,A12,P106_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR030W,DFG16,ZRG12;ECM41,"Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p",pseudohyphal growth,molecular_function,cellular_component,"cellular_component, molecular_function, protein modification process, pseudohyphal growth",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,16,7.4,no,,,,, P106,13,B1,P106_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR031W,CRS5,,"Copper-binding metallothionein, required for wild-type copper resistance",response to chemical stimulus,other,cytoplasm,"cytoplasm, other, response to chemical stimulus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,8,3.7,no,,,,, P106,14,B2,P106_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR032C,HMS1,,Basic helix-loop-helix (bHLH) protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant,pseudohyphal growth,other,cellular_component,"DNA binding, cellular_component, pseudohyphal growth, transcription regulator activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,12,6.4,no,,,,, P106,15,B3,P106_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR033C,EXO1,DHS1,"5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains","response to stress, chromosome organization, cell cycle, DNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, response to stress",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,12,7.3,no,,,,, P106,16,B4,P106_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR034C,AKR2,,Ankyrin repeat-containing protein similar to Akr1p; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p,"transport, vesicle-mediated transport, protein modification process, cellular membrane organization",transferase activity,"cytoplasm, Golgi apparatus","cellular_component, membrane organization and biogenesis, protein modification process, transferase activity, transport, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,28,11.6,no,,,,, P106,17,B5,P106_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR035C,SHE4,DIM1,"Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization","cytoskeleton organization, DNA metabolic process",protein binding,cytoplasm,"DNA metabolic process, cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,4,2.4,no,,,,, P106,18,B6,P106_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR036W,PEP12,VPT13;VPS6;VPL6,"Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin","vacuole organization, transport, vesicle-mediated transport",protein binding,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, protein binding, transport, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,18,9.2,no,,,,, P106,19,B7,P106_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR037W,CYC2,,"Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)","mitochondrion organization, protein modification process, protein complex biogenesis, cellular membrane organization",oxidoreductase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, oxidoreductase activity, protein modification process",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,12,4.8,no,,,,, P106,20,B8,P106_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR038C,HIR2,SPT1,"Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p","chromosome organization, transcription, RNA metabolic process","transcription regulator activity, DNA binding, protein binding",nucleus,"DNA binding, RNA metabolic process, nucleus, organelle organization and biogenesis, other, protein binding, transcription, transcription regulator activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,205,9,4.4,no,,,,, P106,21,B9,P106_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR039W,CKB2,,"Beta' regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB1, the many substrates include transcription factors and all RNA polymerases","response to stress, transcription, protein modification process, RNA metabolic process",enzyme regulator activity,"nucleus, nucleolus","DNA metabolic process, RNA metabolic process, anatomical structure morphogenesis, cell cycle, cellular homeostasis, cytoplasm, enzyme regulator activity, nucleolus, nucleus, other, protein modification process, response to stress, transcription, transposition",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,42,13.5,no,,,,, P106,22,B10,P106_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR040W,GLO4,,"Mitochondrial glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate",cellular carbohydrate metabolic process,hydrolase activity,"mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, hydrolase activity, mitochondrion, response to chemical stimulus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,20,10.5,no,,,,, P106,23,B11,P106_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR041C,,SRF5,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the uncharacterized gene CUE5; deletion in cyr1 mutant results in loss of stress resistance",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,12,7.1,no,,,,, P106,24,B12,P106_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR042W,CUE5,,"Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern",biological_process,protein binding,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,20,10.6,no,,,,, P106,25,C1,P106_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR043W,WHI2,,"Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression","transport, response to stress, vesicle-mediated transport, cytoskeleton organization, cellular membrane organization",enzyme regulator activity,cellular_component,"cellular_component, cytoskeleton organization and biogenesis, enzyme regulator activity, membrane organization and biogenesis, organelle organization and biogenesis, other, response to stress, transport, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,10,3.9,no,,,,, P106,26,C2,P106_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR044W,IRC23,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; null mutant displays increased levels of spontaneous Rad52p foci,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,32,18.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P106,27,C3,P106_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR045W,TOM6,MOM8B;ISP6,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex,"transport, mitochondrion organization",transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,37,18.4,no,,,,, P106,28,C4,P106_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR047C,STD1,SFS3;MSN3,"Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p","response to stress, cellular carbohydrate metabolic process, signaling process, transcription, RNA metabolic process",enzyme regulator activity,"nucleus, membrane, plasma membrane","RNA metabolic process, carbohydrate metabolic process, enzyme regulator activity, nucleus, plasma membrane, response to stress, signal transduction, transcription",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,30,10.2,no,,,,, P106,29,C5,P106_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR049C,RSB1,,Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane,"transport, cellular membrane organization","hydrolase activity, transporter activity","membrane, endoplasmic reticulum, cytoplasm, plasma membrane","endoplasmic reticulum, hydrolase activity, membrane, membrane organization and biogenesis, plasma membrane, response to chemical stimulus, transport, transporter activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,18,6.5,no,,,,, P106,30,C6,P106_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR050C,,YOR29-01,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutation is viable",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,20,7.3,no,,,,, P106,31,C7,P106_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR051C,ETT1,YOR29-02,"Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts; deletion increases stop codon readthrough",translation,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,42,6,14.3,no,,,,, P106,32,C8,P106_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR052C,,YOR29-03,"Nuclear protein of unknown function; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner and by weak acid",biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,18,9.9,no,,,,, P106,33,C9,P106_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR053W,,YOR29-04,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene VHS3/YOR054C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,15,8.8,no,,,,, P106,34,C10,P106_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR054C,VHS3,YOR29-05,"Negative regulatory subunit of protein phosphatase 1 Ppz1p and also a subunit of the phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex, which catalyzes the third step of coenzyme A biosynthesis","cofactor metabolic process, cellular homeostasis","lyase activity, enzyme regulator activity",cytoplasm,"cell cycle, cellular homeostasis, cellular_component, cofactor metabolic process, enzyme regulator activity, lyase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,17,7.7,no,,,,, P106,35,C11,P106_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR055W,,YOR29-06,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,23,11.5,no,,,,, P106,36,C12,P106_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR058C,ASE1,YOR29-09,Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate,"cytoskeleton organization, cytokinesis, cell cycle, protein complex biogenesis",protein binding,"nucleus, cytoskeleton","cell cycle, cytokinesis, cytoskeleton, cytoskeleton organization and biogenesis, nucleus, organelle organization and biogenesis, protein binding",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,33,18.8,no,,,,, P106,37,D1,P106_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR059C,,YOR29-10,Hypothetical protein,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,20,8.7,no,,,,, P106,38,D2,P106_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR061W,CKA2,YOR29-12,"Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases","response to stress, transcription, protein modification process, RNA metabolic process","transferase activity, protein kinase activity","nucleus, nucleolus","RNA metabolic process, anatomical structure morphogenesis, cell cycle, cellular homeostasis, cytoplasm, nucleolus, nucleus, other, protein kinase activity, protein modification process, response to stress, transcription, transferase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,28,14.3,no,,,,, P106,39,D3,P106_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR062C,,YOR29-13,Protein of unknown function; similar to YKR075Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,26,9.4,no,,,,, P106,40,D4,P106_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR064C,YNG1,YOR29-15,"Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1","chromosome organization, protein modification process","transferase activity, protein binding",nucleus,"nucleus, organelle organization and biogenesis, protein binding, protein modification process, transferase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,28,12.3,no,,,,, P106,41,D5,P106_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR066W,MSA1,YOR29-17,"Activator of G1-specific transcription factors, MBF and SBF; involved in regulation of the timing of G1-specific gene transcription and cell cycle initiation; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation","transcription, cell cycle, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cell cycle, cellular_component, molecular_function, other, transcription",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,17,8.5,no,,,,, P106,42,D6,P106_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR067C,ALG8,YOR29-18,"Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p","protein modification process, cellular carbohydrate metabolic process, cellular lipid metabolic process",transferase activity,"endomembrane system, membrane, endoplasmic reticulum, cytoplasm","carbohydrate metabolic process, cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, protein modification process, transferase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,18,10.3,no,,,,, P106,43,D7,P106_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR068C,VAM10,YOR29-19,Protein involved in vacuole morphogenesis; acts at an early step of homotypic vacuole fusion that is required for vacuole tethering,"vacuole organization, cellular membrane organization",molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, vacuole",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,35,19,no,,,,, P106,44,D8,P106_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR069W,VPS5,YOR29-20;VPT5;PEP10;GRD2,Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p,"transport, vesicle-mediated transport","transporter activity, lipid binding","membrane, endomembrane system, cytoplasm","cytoplasm, endomembrane system, lipid binding, membrane, other, transport, transporter activity, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,16,6.2,no,,,,, P106,45,D9,P106_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR070C,GYP1,YOR29-21,"Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion","transport, vesicle-mediated transport",enzyme regulator activity,"mitochondrion, cytoplasm, Golgi apparatus","Golgi apparatus, enzyme regulator activity, mitochondrion, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,4,2.1,no,,,,, P106,46,D10,P106_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR071C,NRT1,THI71;YOR29-22,High-affinity nicotinamide riboside transporter; also transports thiamine with low affinity; shares sequence similarity with Thi7p and Thi72p; proposed to be involved in 5-fluorocytosine sensitivity,transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,50,15,no,,,,, P106,47,D11,P106_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR072W,,YOR29-23,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,14,7.1,no,,,,, P106,48,D12,P106_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR073W,SGO1,YOR29-24,"Component of the spindle checkpoint, involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability","signaling process, cytoskeleton organization, chromosome segregation, meiosis, chromosome organization, cell cycle",molecular_function,"nucleus, cytoskeleton, microtubule organizing center, chromosome, cytoplasm","cell cycle, chromosome, cytoplasm, cytoskeleton, meiosis, microtubule organizing center, molecular_function, nucleus, organelle organization and biogenesis",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,295,69,23.4,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P106,49,E1,P106_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR076C,SKI7,YOR29-27,Coupling protein that mediates interactions between the Ski complex and the cytoplasmic exosome during 3'-5' RNA degradation; eRF3-like domain targets nonstop mRNA for degradation; null mutants have superkiller phenotype,RNA metabolic process,protein binding,cytoplasm,"RNA metabolic process, cytoplasm, other, protein binding, response to chemical stimulus",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,239,1,0.4,no,,,,, P106,50,E2,P106_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR078W,BUD21,YOR29-29;UTP16,Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern,"ribosome biogenesis, RNA metabolic process",RNA binding,"nucleus, nucleolus","RNA binding, RNA metabolic process, cytoplasm, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,20,8.3,no,,,,, P106,51,E3,P106_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR079C,ATX2,YOR29-30,"Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation",cellular homeostasis,transporter activity,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cellular homeostasis, cytoplasm, endomembrane system, membrane, transporter activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,144,6,4.2,no,,,,, P106,52,E4,P106_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR080W,DIA2,YOR29-31,"Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication, involved in invasive and pseudohyphal growth","DNA metabolic process, protein modification process, cellular protein catabolic process","DNA binding, ligase activity","nucleus, chromosome","DNA binding, DNA metabolic process, other, protein modification process",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,12,6.8,no,,,,, P106,53,E5,P106_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR081C,TGL5,STC2,Bifunction enzyme with triacylglycerol lipase and lysophosphatidic acid acyltransferase activity; involved in triacylglycerol mobilization; localizes to lipid particles; potential Cdc28p substrate,cellular lipid metabolic process,"transferase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, lipid metabolic process",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,18,6.9,no,,,,, P106,54,E6,P106_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR082C,,,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene YOR083W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,16,5.3,no,,,,, P106,55,E7,P106_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR083W,WHI5,,"Repressor of G1 transcription that binds to SCB binding factor (SBF) at SCB target promoters in early G1; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5; periodically expressed in G1","transcription, cell cycle, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","cell cycle, cytoplasm, nucleus, other, transcription regulator activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,10,3.5,no,,,,, P106,56,E8,P106_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR084W,LPX1,,"Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction",peroxisome organization,hydrolase activity,"peroxisome, cytoplasm","cytoplasm, hydrolase activity, organelle organization and biogenesis, peroxisome",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,6,3.8,no,,,,, P106,57,E9,P106_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR085W,OST3,,"Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins","protein modification process, protein complex biogenesis, cellular carbohydrate metabolic process",transferase activity,"endomembrane system, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, other, protein modification process, transferase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,8,4.5,no,,,,, P106,58,E10,P106_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR086C,TCB1,,"Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact",biological_process,lipid binding,"membrane fraction, mitochondrion, cytoplasm","biological_process, lipid binding, mitochondrion",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,18,10.6,no,,,,, P106,59,E11,P106_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR087W,YVC1,TRPY1;YOR088W,"Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock",cellular homeostasis,transporter activity,"membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, transporter activity, vacuole",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,48,14.5,no,,,,, P106,60,E12,P106_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR087W,YVC1,TRPY1;YOR088W,"Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock",cellular homeostasis,transporter activity,"membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, transporter activity, vacuole",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,3,1.7,no,,,,, P106,61,F1,P106_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR089C,VPS21,YPT51;YPT21;VPT12;VPS12,Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog,"vacuole organization, transport, vesicle-mediated transport, cellular membrane organization",hydrolase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, hydrolase activity, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, other, transport, vesicle-mediated transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,22,9.4,no,,,,, P106,62,F2,P106_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR090C,PTC5,PPP1,Mitochondrial type 2C protein phosphatase involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p,protein modification process,"phosphoprotein phosphatase activity, hydrolase activity","mitochondrion, cytoplasm","hydrolase activity, mitochondrion, other, phosphoprotein phosphatase activity, protein modification process",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,24,9.5,no,,,,, P106,63,F3,P106_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR091W,TMA46,RBF46,Protein of unknown function that associates with ribosomes; interacts with GTPase Rbg1p,biological_process,molecular_function,"ribosome, cytoplasm","cytoplasm, molecular_function, ribosome, ribosome biogenesis",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,2,1.1,no,,,,, P106,64,F4,P106_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR092W,ECM3,YOR3165W,Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation,fungal-type cell wall organization,hydrolase activity,"endoplasmic reticulum, cytoplasm","cell wall organization and biogenesis, endoplasmic reticulum, hydrolase activity",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,158,18,11.4,no,,,,, P106,65,F5,P106_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR093C,,,Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-inducing agents,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,31,18,no,,,,, P106,66,F6,P106_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR094W,ARF3,ARL2,"Glucose-repressible ADP-ribosylation factor, GTPase of the Ras superfamily involved in development of polarity","transport, cytoskeleton organization, cytokinesis, vesicle-mediated transport, cellular lipid metabolic process, cell cycle, cellular membrane organization",hydrolase activity,"cellular bud, site of polarized growth","anatomical structure morphogenesis, cellular bud, cytokinesis, cytoskeleton organization and biogenesis, hydrolase activity, organelle organization and biogenesis, other, site of polarized growth, transport",,,15_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,18,6,no,,,,, P106,67,F7,P106_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR289W,,,Putative protein of unknown function; transcription induced by the unfolded protein response; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,2,0.6,no,,,,, P106,68,F8,P106_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER070W,RNR1,SDS12;RIR1;CRT7,"Major isoform of the large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits",other,oxidoreductase activity,cytoplasm,"cytoplasm, other, oxidoreductase activity",,,05_3,,,rg notes: FAILED QC-MM OK-REMAKE-NDS CS QC; consortium notes: FAILED QC,DIC:cell structure;YFP:Rad52-YFP protein,,188,11,5.9,no,,,,, P106,69,F9,P106_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR291W,YPK9,,"Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor?Rakeb syndrome",biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, membrane, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,16,7.2,no,,,,, P106,70,F10,P106_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR292C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YOR292C is not an essential gene,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,22,10.8,no,,,,, P106,71,F11,P106_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR293W,RPS10A,S10A,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10,"transport, translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,8,3,no,,,,, P106,72,F12,P106_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR295W,UAF30,,"Subunit of UAF (upstream activation factor), which is an RNA polymerase I specific transcription stimulatory factor composed of Uaf30p, Rrn5p, Rrn9p, Rrn10p, histones H3 and H4; deletion decreases cellular growth rate","transcription, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, nucleolus","DNA binding, RNA metabolic process, nucleolus, nucleus, transcription, transcription regulator activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,8,4.5,no,,,,, P106,73,G1,P106_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR296W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; expressed during copper starvation; YOR296W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,16,5.1,no,,,,, P106,74,G2,P106_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR297C,TIM18,,Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane; may mediate assembly or stability of the complex,"transport, mitochondrion organization, response to chemical stimulus, response to stress, cellular membrane organization",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, response to chemical stimulus, response to stress, transport, transporter activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,26,10.7,no,,,,, P106,75,G3,P106_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR298W,MUM3,,Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acyltransferases,"sporulation resulting in formation of a cellular spore, cellular lipid metabolic process, cellular component morphogenesis",transferase activity,cellular_component,"cell wall organization and biogenesis, cellular_component, lipid metabolic process, sporulation, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,4,2.4,no,,,,, P106,76,G4,P106_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR299W,BUD7,,"Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane","transport, cellular carbohydrate metabolic process, vesicle-mediated transport, cytokinesis, cell cycle",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, anatomical structure morphogenesis, carbohydrate metabolic process, cell wall organization and biogenesis, cytokinesis, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, transport, vesicle-mediated transport",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,30,14.4,no,,,,, P106,77,G5,P106_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR301W,RAX1,,Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily,"cytokinesis, cell cycle",molecular_function,"cellular bud, membrane, site of polarized growth","anatomical structure morphogenesis, cellular bud, cytokinesis, membrane, molecular_function, site of polarized growth",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,28,10.8,no,,,,, P106,78,G6,P106_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR302W,,,"CPA1 uORF, Arginine attenuator peptide, regulates translation of the CPA1 mRNA",translation,translation regulator activity,cytoplasm,"cytoplasm, translation, translation regulator activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,23,12.4,no,,,,, P106,79,G7,P106_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR303W,CPA1,,"Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader",cellular amino acid and derivative metabolic process,ligase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, ligase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,14,7,no,,,,, P106,80,G8,P106_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR304C-A,,,"Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck",biological_process,molecular_function,"cellular bud, site of polarized growth, cytoplasm","biological_process, cellular bud, cytoplasm, molecular_function, site of polarized growth",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,4,1.2,no,,,,, P106,81,G9,P106_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR304W,ISW2,,"ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth","chromosome organization, transcription, response to chemical stimulus, RNA metabolic process","DNA binding, hydrolase activity",nucleus,"RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, response to chemical stimulus, transcription",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,18,5.7,no,,,,, P106,82,G10,P106_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR307C,SLY41,,Protein involved in ER-to-Golgi transport,"transport, vesicle-mediated transport",molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, transport, vesicle-mediated transport",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,8,3.5,no,,,,, P106,83,G11,P106_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR308C,SNU66,,Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; also required for pre-5S rRNA processing and may act in concert with Rnh70p; has homology to human SART-1,"ribosome biogenesis, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, nucleus, other",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,14,4.6,no,,,,, P106,84,G12,P106_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR311C,DGK1,HSD1,"Diacylglycerol kinase, localized to the endoplasmic reticulum (ER); overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation; contains a CTP transferase domain",cellular lipid metabolic process,transferase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,48,15.3,no,,,,, P106,85,H1,P106_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR312C,RPL20B,L20B;L18B;RPL18A1,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, ribosome biogenesis, structural molecule activity, translation",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,212,38,17.9,no,,,,, P106,86,H2,P106_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR313C,SPS4,,Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage,sporulation resulting in formation of a cellular spore,molecular_function,cellular_component,"cellular_component, molecular_function, sporulation",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,10,5.7,no,,,,, P106,87,H3,P106_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P106,88,H4,P106_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR314W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,6,3.3,no,,,,, P106,89,H5,P106_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR315W,SFG1,,"Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate","pseudohyphal growth, transcription, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, pseudohyphal growth, transcription, transcription regulator activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,184,18,9.8,no,,,,, P106,90,H6,P106_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR316C,COT1,,Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium,"transport, cellular homeostasis",transporter activity,"vacuole, mitochondrion, cytoplasm","cellular homeostasis, cytoplasm, mitochondrion, transport, transporter activity, vacuole",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,237,16,6.8,no,,,,, P106,91,H7,P106_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR320C,GNT1,,N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus,"cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, protein modification process, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,22,7.5,no,,,,, P106,92,H8,P106_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR321W,PMT3,,"Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; target for new antifungals","cellular carbohydrate metabolic process, protein modification process",transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, protein modification process, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,20,7.9,no,,,,, P106,93,H9,P106_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR322C,LDB19,ART1,Protein involved in regulating the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target; localization changes in response to nutrient levels; null mutant has reduced affinity for alcian blue dye,"transport, vesicle-mediated transport, cellular membrane organization",protein binding,"cytoplasmic membrane-bounded vesicle, cytoplasm","biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,42,16,no,,,,, P106,94,H10,P106_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR323C,PRO2,,"Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis","cellular amino acid and derivative metabolic process, heterocycle metabolic process",oxidoreductase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, nucleus, oxidoreductase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,10,3.9,no,,,,, P106,95,H11,P106_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR324C,FRT1,HPH1,"Tail-anchored, endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress",response to stress,molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, response to stress",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,16,8.7,no,,,,, P106,96,H12,P106_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR327C,SNC2,,Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins,"transport, vesicle-mediated transport, vesicle organization, cellular membrane organization",protein binding,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,52,16,no,,,,, P107,1,A1,P107_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR328W,PDR10,,"ATP-binding cassette (ABC) transporter, multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p","transport, response to chemical stimulus","transporter activity, hydrolase activity","membrane, plasma membrane","hydrolase activity, plasma membrane, response to chemical stimulus, transport, transporter activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,47,22.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P107,2,A2,P107_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR332W,VMA4,,"Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,1,0.5,no,,,,, P107,3,A3,P107_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR334W,MRS2,,"Mitochondrial inner membrane Mg(2+) channel, required for maintenance of intramitochondrial Mg(2+) concentrations at the correct level to support splicing of group II introns",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","RNA metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,21,10.9,no,,,,, P107,4,A4,P107_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR337W,TEA1,,Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein,transcription,DNA binding,nucleus,"DNA binding, nucleus, transcription",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,19,9.8,no,,,,, P107,5,A5,P107_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR338W,,,Putative protein of unknown function; YOR338W transcription is regulated by Azf1p and its transcript is a specific target of the G protein effector Scp160p; identified as being required for sporulation in a high-throughput mutant screen,"sporulation resulting in formation of a cellular spore, transcription, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, cellular_component, molecular_function, sporulation, transcription",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,12,3.6,no,,,,, P107,6,A6,P107_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR339C,UBC11,,"Ubiquitin-conjugating enzyme most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2",protein modification process,ligase activity,cytoplasm,"cytoplasm, ligase activity, protein modification process",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,15,8.6,no,,,,, P107,7,A7,P107_A7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P107,8,A8,P107_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR342C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,10,5.8,no,,,,, P107,9,A9,P107_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR343C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,20,6.5,no,,,,, P107,10,A10,P107_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR344C,TYE7,SGC1,Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression,"cellular carbohydrate metabolic process, transcription, generation of precursor metabolites and energy",DNA binding,"nucleus, chromosome","DNA binding, RNA metabolic process, carbohydrate metabolic process, cell cycle, generation of precursor metabolites and energy, nucleus, transcription, transcription regulator activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,32,10.5,no,,,,, P107,11,A11,P107_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR346W,REV1,,"Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA","response to stress, DNA metabolic process","transferase activity, nucleotidyltransferase activity","nucleus, chromosome, mitochondrion, cytoplasm","DNA metabolic process, mitochondrion, nucleotidyltransferase activity, nucleus, response to stress, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,16,7.5,no,,,,, P107,12,A12,P107_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR347C,PYK2,,"Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux",other,transferase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,23,12,no,,,,, P107,13,B1,P107_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR348C,PUT4,,"Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells","transport, cellular amino acid and derivative metabolic process, heterocycle metabolic process",transporter activity,"membrane, plasma membrane","amino acid and derivative metabolic process, plasma membrane, transport, transporter activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,8,4.5,no,,,,, P107,14,B2,P107_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR349W,CIN1,,Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl,protein folding,protein binding,cellular_component,"cellular_component, protein binding, protein folding",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,11,6.3,no,,,,, P107,15,B3,P107_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR350C,MNE1,,Mitochondrial protein similar to Lucilia illustris mitochondrial cytochrome oxidase,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,16,8.7,no,,,,, P107,16,B4,P107_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR351C,MEK1,MRE4,"Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids","meiosis, signaling process, cell cycle, protein modification process","transferase activity, protein kinase activity",nucleus,"meiosis, nucleus, protein kinase activity, protein modification process, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,11,5.3,no,,,,, P107,17,B5,P107_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR352W,,,"Putative protein of unknown function; expression levels regulated by Arg5,6p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,22,10,no,,,,, P107,18,B6,P107_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR354C,MSC6,,"Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","meiosis, cell cycle, DNA metabolic process",molecular_function,"mitochondrion, cytoplasm","DNA metabolic process, cell cycle, meiosis, mitochondrion, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,13,6.5,no,,,,, P107,19,B7,P107_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR355W,GDS1,,"Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","generation of precursor metabolites and energy, cellular respiration",molecular_function,"nucleus, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, molecular_function, nucleus",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,24,12.1,no,,,,, P107,20,B8,P107_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR356W,,,Mitochondrial protein with similarity to flavoprotein-type oxidoreductases; found in a large supramolecular complex with other mitochondrial dehydrogenases,biological_process,molecular_function,"mitochondrion, cytoplasm","cofactor metabolic process, mitochondrion, oxidoreductase activity, vitamin metabolic process",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,7,3.1,no,,,,, P107,21,B9,P107_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR357C,SNX3,GRD19,Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p,"transport, vesicle-mediated transport","protein binding, lipid binding",cytoplasm,"cytoplasm, lipid binding, other, protein binding, transport, vesicle-mediated transport",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,18,5.9,no,,,,, P107,22,B10,P107_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR358W,HAP5,,"Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex",transcription,"transcription regulator activity, DNA binding",nucleus,"DNA binding, carbohydrate metabolic process, nucleus, transcription, transcription regulator activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,28,13.3,no,,,,, P107,23,B11,P107_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR359W,VTS1,,"Post-transcriptional gene regulator, flap-structured DNA-binding and RNA-binding protein; shows genetic interactions with Vti1p, a v-SNARE involved in cis-Golgi membrane traffic; stimulates Dna2p endonuclease activity; contains a SAM domain",RNA metabolic process,"RNA binding, DNA binding","nucleus, cytoplasm","RNA binding, RNA metabolic process, cytoplasm",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,28,8.3,no,,,,, P107,24,B12,P107_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR360C,PDE2,SRA5,"High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon",signaling process,hydrolase activity,"nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, signal transduction",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,6,2.9,no,,,,, P107,25,C1,P107_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR363C,PIP2,OAF2,"Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)-Cys(6) cluster domain, forms heterodimer with Oaf1p, binds oleate response elements (OREs), activates beta-oxidation genes","cellular lipid metabolic process, transcription, peroxisome organization",transcription regulator activity,nucleus,"lipid metabolic process, nucleus, organelle organization and biogenesis, response to chemical stimulus, transcription, transcription regulator activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,12,7,no,,,,, P107,26,C2,P107_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR365C,,,Putative protein of unknown function; YOR365C is not an essential protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,1,0.5,no,,,,, P107,27,C3,P107_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR367W,SCP1,,"Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin",cytoskeleton organization,protein binding,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,20,10.5,no,,,,, P107,28,C4,P107_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR368W,RAD17,,"Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins","signaling process, response to stress, meiosis, cell cycle, DNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, meiosis, nucleus, response to stress, signal transduction",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,26,13.8,no,,,,, P107,29,C5,P107_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR371C,GPB1,KRH2,"Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; promotes ubiquitin-dependent proteolysis of Ira2p; regulated by G-alpha protein Gpa2p; homolog of Gpb2p","signaling process, response to chemical stimulus, protein modification process, pseudohyphal growth, cellular protein catabolic process","enzyme regulator activity, signal transducer activity, protein binding","membrane, cytoplasm, plasma membrane","cytoplasm, enzyme regulator activity, other, plasma membrane, protein binding, pseudohyphal growth, response to chemical stimulus, signal transducer activity, signal transduction",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,26,12.5,no,,,,, P107,30,C6,P107_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR374W,ALD4,ALDH2;ALD7,"Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed",cofactor metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,7,3.8,no,,,,, P107,31,C7,P107_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR376W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YOR376W is not an essential gene.",biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,18,9.6,no,,,,, P107,32,C8,P107_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR377W,ATF1,,Alcohol acetyltransferase with potential roles in lipid and sterol metabolism; responsible for the major part of volatile acetate ester production during fermentation,"cellular lipid metabolic process, generation of precursor metabolites and energy",transferase activity,"endomembrane system, cytoplasm","cytoplasm, endomembrane system, generation of precursor metabolites and energy, lipid metabolic process, other, transferase activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,52,16.1,no,,,,, P107,33,C9,P107_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR378W,,,"Putative paralog of ATR1, but not required for boron tolerance; member of the DHA2 family of drug:H+ antiporters; YOR378W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,2,1.1,no,,,,, P107,34,C10,P107_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR380W,RDR1,,Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins,response to chemical stimulus,DNA binding,nucleus,"DNA binding, nucleus, response to chemical stimulus, transcription regulator activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,13,5.7,no,,,,, P107,35,C11,P107_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR381W,FRE3,,"Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels","transport, cellular homeostasis",oxidoreductase activity,"membrane, plasma membrane","cellular homeostasis, membrane, oxidoreductase activity, plasma membrane, transport",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,23,11.1,no,,,,, P107,36,C12,P107_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR382W,FIT2,,"Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall",transport,molecular_function,cell wall,"cell wall, molecular_function, transport",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,18,7.6,no,,,,, P107,37,D1,P107_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR383C,FIT3,,"Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall",transport,molecular_function,cell wall,"cell wall, molecular_function, transport",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,8,2.7,no,,,,, P107,38,D2,P107_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR384W,FRE5,,"Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,oxidoreductase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, oxidoreductase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,8,4.1,no,,,,, P107,39,D3,P107_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR385W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YOR385W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,20,11.5,no,,,,, P107,40,D4,P107_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR386W,PHR1,,"DNA photolyase involved in photoreactivation, repairs pyrimidine dimers in the presence of visible light; induced by DNA damage; regulated by transcriptional repressor Rph1p","response to stress, DNA metabolic process",lyase activity,"nucleus, mitochondrion, cytoplasm","DNA metabolic process, lyase activity, mitochondrion, nucleus, response to stress",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,12,6.6,no,,,,, P107,41,D5,P107_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL001W,PHO80,phoR;VAC5;TUP7;AGS3,"Cyclin, interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and environmental conditions, including the response to phosphate limitation and stress-dependent calcium signaling","signaling process, transcription, response to stress, cell cycle, cellular homeostasis, RNA metabolic process",enzyme regulator activity,nucleus,"RNA metabolic process, cell cycle, enzyme regulator activity, nucleus, other, signal transduction, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,12,6.8,no,,,,, P107,42,D6,P107_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL002C,IZH2,PHO36,"Plasma membrane protein involved in zinc homeostasis and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc","cellular lipid metabolic process, cellular homeostasis, response to chemical stimulus",protein binding,"membrane, plasma membrane","cellular homeostasis, lipid metabolic process, membrane, other, plasma membrane, protein binding, response to chemical stimulus",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,42,22.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P107,43,D7,P107_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL003C,PFA4,,"Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases",protein modification process,transferase activity,"endoplasmic reticulum, cytoplasm","cellular_component, protein modification process, transferase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,7,4,no,,,,, P107,44,D8,P107_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL004W,SIN3,UME4;SDS16;SDI1;RPD1;GAM2;CPE1,"Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity","transcription, protein modification process, response to stress, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process","transcription regulator activity, protein binding","nucleus, chromosome","DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, protein binding, protein modification process, response to stress, transcription, transcription regulator activity, transposition",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,4,2.4,no,,,,, P107,45,D9,P107_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL006C,TOP1,MAK17;MAK1,"Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination","transcription, chromosome segregation, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process","isomerase activity, DNA binding","nucleus, chromosome, nucleolus","DNA binding, DNA metabolic process, RNA metabolic process, cell cycle, isomerase activity, nucleolus, nucleus, organelle organization and biogenesis, other, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,10,4.9,no,,,,, P107,46,D10,P107_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL007C,CSI2,,Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene,biological_process,molecular_function,"cellular bud, site of polarized growth, vacuole, cytoplasm","biological_process, cellular bud, cytoplasm, molecular_function, site of polarized growth, vacuole",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,20,11,no,,,,, P107,47,D11,P107_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL008W,COQ10,,"Coenzyme Q (ubiquinone) binding protein, functions in the delivery of Q6 to its proper location for electron transport during respiration; START domain protein with homologs in bacteria and eukaryotes","generation of precursor metabolites and energy, cellular respiration",other,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cellular respiration, cytoplasm, membrane, mitochondrial envelope, mitochondrion, other",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,20,9.3,no,,,,, P107,48,D12,P107_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL011W,PLB3,,Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro,cellular lipid metabolic process,hydrolase activity,"membrane, extracellular region, plasma membrane","extracellular region, hydrolase activity, lipid metabolic process, plasma membrane",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,14,4.7,no,,,,, P107,49,E1,P107_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL012C,HTZ1,H2AZ;H2A.F/Z;HTA3,"Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin","transcription, RNA metabolic process",other,"nucleus, chromosome","RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, other, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,16,5.9,no,,,,, P107,50,E2,P107_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL013C,HRD1,DER3,Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger,"fungal-type cell wall organization, cellular protein catabolic process",ligase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, ligase activity, membrane, protein catabolic process",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,8,4.4,no,,,,, P107,51,E3,P107_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL014W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,26,8.5,no,,,,, P107,52,E4,P107_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL015W,IRC10,,Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,48,22.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P107,53,E5,P107_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL017W,ESC8,,"Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex","transcription, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,20,11.2,no,,,,, P107,54,E6,P107_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL018C,TLG2,,"Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation","transport, vesicle organization, vesicle-mediated transport, cellular lipid metabolic process, cellular membrane organization",protein binding,"membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,10,4.6,no,,,,, P107,55,E7,P107_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL019W,,TOS7,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole,biological_process,molecular_function,"membrane, vacuole, plasma membrane, cytoplasm","biological_process, cytoplasm, molecular_function, plasma membrane, vacuole",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,14,7.6,no,,,,, P107,56,E8,P107_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL020W,TAT2,TAP2;SCM2;SAB2;LTG3,"High affinity tryptophan and tyrosine permease, overexpression confers FK506 and FTY720 resistance",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,12,5.9,no,,,,, P107,57,E9,P107_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL023W,IFM1,,Mitochondrial translation initiation factor 2,"mitochondrion organization, translation","RNA binding, hydrolase activity","mitochondrion, cytoplasm","RNA binding, hydrolase activity, mitochondrion, translation, translation regulator activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,13,6.4,no,,,,, P107,58,E10,P107_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL024W,,,Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,16,7.8,no,,,,, P107,59,E11,P107_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL025W,LAG2,ECM36,"Protein that negatively regulates the SCF E3-ubiquitin ligase by interacting with and preventing neddyation of the cullin subunit, Cdc53p; longevity determinant that is preferentially expressed in young cells; similar to mammalian Cand1",protein modification process,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, other",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,48,21.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P107,60,E12,P107_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL027C,MDM38,MKH1,"Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome","transport, mitochondrion organization, cellular homeostasis, cellular membrane organization",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular homeostasis, cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, transport",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,24,8.8,no,,,,, P107,61,F1,P107_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL028C,YAP7,,Putative basic leucine zipper (bZIP) transcription factor,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,8,4.5,no,,,,, P107,62,F2,P107_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL029C,,,Putative protein of unknown function; identified as interacting with Hsc82p and Hsp82p in high-throughput two-hybrid screens,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,32,11.5,no,,,,, P107,63,F3,P107_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL030W,GAS5,,"1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall",biological_process,transferase activity,"cell wall, membrane fraction","biological_process, cell wall, membrane fraction, transferase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,20,8.1,no,,,,, P107,64,F4,P107_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL031C,SIL1,SLS1,"Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein",transport,enzyme regulator activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, other, transport",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,8,2.5,no,,,,, P107,65,F5,P107_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL032W,OPI10,,"Protein with a possible role in phospholipid biosynthesis, based on inositol-excreting phenotype of the null mutant and its suppression by exogenous choline",cellular carbohydrate metabolic process,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, other",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,10,4.8,no,,,,, P107,66,F6,P107_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL035C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,16,9.4,no,,,,, P107,67,F7,P107_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL036W,,,Protein of unknown function; potential Cdc28p substrate,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,16,8.6,no,,,,, P107,68,F8,P107_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL037C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOL036W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,61,25.5,no,,,,, P107,69,F9,P107_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL039W,RPP2A,RPLA2;RPL44,"Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,156,2,1.3,no,,,,, P107,70,F10,P107_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL041C,NOP12,,Nucleolar protein involved in pre-25S rRNA processing and biogenesis of large 60S ribosomal subunit; contains an RNA recognition motif (RRM); binds to Ebp2; similar to Nop13p and Nsr1p,"ribosome biogenesis, RNA metabolic process",RNA binding,"nucleus, nucleolus","RNA binding, RNA metabolic process, nucleolus",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,14,4.5,no,,,,, P107,71,F11,P107_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL042W,NGL1,,"Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,hydrolase activity,"mitochondrion, cytoplasm","biological_process, hydrolase activity, mitochondrion",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,29,12.4,no,,,,, P107,72,F12,P107_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL043C,NTG2,SCR2,"DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus; sumoylated","response to stress, DNA metabolic process","lyase activity, hydrolase activity",nucleus,"DNA metabolic process, hydrolase activity, lyase activity, nucleus, response to stress",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,14,6,no,,,,, P107,73,G1,P107_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL044W,PEX15,PAS21,"Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly","transport, signaling process, peroxisome organization",protein binding,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, other, peroxisome, protein binding, signal transduction, transport",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,10,5.3,no,,,,, P107,74,G2,P107_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL045W,PSK2,,"One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation)","cellular carbohydrate metabolic process, generation of precursor metabolites and energy, protein modification process","transferase activity, protein kinase activity","mitochondrion, cytoplasm","carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, mitochondrion, protein kinase activity, protein modification process, transferase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,18,9,no,,,,, P107,75,G3,P107_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL046C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data;almost completely overlaps the verified gene PSK2/YOL045W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,11,5,no,,,,, P107,76,G4,P107_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL047C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,23,10.5,no,,,,, P107,77,G5,P107_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL048C,RRT8,,Putative protein of unknown function; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,10,5.1,no,,,,, P107,78,G6,P107_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL049W,GSH2,,"Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock","cofactor metabolic process, cellular amino acid and derivative metabolic process",ligase activity,other,"cofactor metabolic process, ligase activity, other, response to stress",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,42,20.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P107,79,G7,P107_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL050C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps verified gene GAL11; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,16,5.5,no,,,,, P107,80,G8,P107_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL051W,GAL11,MED15;ABE1;SPT13;SDS4;RAR3,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,42,18.9,no,,,,, P107,81,G9,P107_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL052C,SPE2,,"S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically","cofactor metabolic process, cellular amino acid and derivative metabolic process",lyase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, lyase activity, nucleus",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,20,6.7,no,,,,, P107,82,G10,P107_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL052C-A,DDR2,YOL053C-A;DDRA2,"Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses",response to stress,molecular_function,"vacuole, cytoplasm","cytoplasm, molecular_function, response to stress, vacuole",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,86,27.9,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P107,83,G11,P107_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL053W,AIM39,,Putative protein of unknown function; null mutant displays elevated frequency of mitochondrial genome loss,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,12,6.6,no,,,,, P107,84,G12,P107_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL054W,PSH1,,"Nuclear protein, putative RNA polymerase II elongation factor; isolated as Pob3p/Spt16p-binding protein","transcription, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,26,8.3,no,,,,, P107,85,H1,P107_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL055C,THI20,,Multifunctional protein with hydroxymethylpyrimidine phosphate (HMP-P) kinase and thiaminase activities; involved in thiamine biosynthesis and degradation; in a gene family with THI21 and THI22; HMP-P kinase activity redundant with Thi21p,"vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process","transferase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, transferase activity, vitamin metabolic process",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,12,3.6,no,,,,, P107,86,H2,P107_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL056W,GPM3,,"Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event",biological_process,"molecular_function, isomerase activity",cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,10,5.4,no,,,,, P107,87,H3,P107_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P107,88,H4,P107_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL057W,,,Dipeptidyl-peptidase III; cleaves dipeptides from the amino terminus of target proteins; highly active on synthetic substrate Arg-Arg-2-naphthylamide; mammalian ortholog may be a biomarker for some cancers,other,"peptidase activity, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, other, peptidase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,29,15.2,no,,,,, P107,89,H5,P107_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL058W,ARG1,ARG10,"Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate",cellular amino acid and derivative metabolic process,ligase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, ligase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,9,4.8,no,,,,, P107,90,H6,P107_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL059W,GPD2,GPD3,"NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria","cofactor metabolic process, cellular carbohydrate metabolic process",oxidoreductase activity,"mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, mitochondrion, other, oxidoreductase activity, vitamin metabolic process",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,6,2.3,no,,,,, P107,91,H7,P107_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL060C,MAM3,,"Protein required for normal mitochondrial morphology, has similarity to hemolysins","mitochondrion organization, cellular homeostasis",molecular_function,"membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, membrane, molecular_function, organelle organization and biogenesis, vacuole",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,18,5.5,no,,,,, P107,92,H8,P107_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL061W,PRS5,,"5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes","fungal-type cell wall organization, cellular carbohydrate metabolic process, heterocycle metabolic process",transferase activity,cytoplasm,"carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, transferase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,158,8,5.1,no,,,,, P107,93,H9,P107_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL062C,APM4,AMP1,Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport,"transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, plasma membrane, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, plasma membrane, transport, vesicle-mediated transport",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,16,6.9,no,,,,, P107,94,H10,P107_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL063C,CRT10,HUS1,Protein involved in transcriptional regulation of RNR2 and RNR3; expression of the gene is induced by DNA damage and null mutations confer increased resistance to hydroxyurea; N-terminal region has a leucine repeat and a WD40 repeat,"transcription, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, cellular_component, molecular_function, response to stress, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,34,10.6,no,,,,, P107,95,H11,P107_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL064C,MET22,3(2)5-bisphosphate nucleotidase;HAL2,"Bisphosphate-3'-nucleotidase, involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway","response to stress, cellular amino acid and derivative metabolic process",hydrolase activity,cellular_component,"amino acid and derivative metabolic process, cytoplasm, hydrolase activity, other, response to chemical stimulus, response to stress",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,325,0,0,no,,,,, P107,96,H12,P107_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL065C,INP54,,"Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins",cellular lipid metabolic process,hydrolase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, lipid metabolic process",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,10,3.1,no,,,,, P108,1,A1,P108_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL067C,RTG1,,"Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus","transcription, protein complex biogenesis, RNA metabolic process","transcription regulator activity, protein binding","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, other, protein binding, signal transduction, transcription, transcription regulator activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,34,11.4,no,,,,, P108,2,A2,P108_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL068C,HST1,,NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance,"chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process",hydrolase activity,"nucleus, chromosome","DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,30,8.9,no,,,,, P108,3,A3,P108_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL070C,NBA1,,"Protein of unknown function, localizes to the bud neck and cytoplasm; interacts with Nap1p; may interact with ribosomes, based on co-purification experiments; potential Cdc28p substrate",biological_process,molecular_function,"cellular bud, site of polarized growth, ribosome, cytoplasm","biological_process, cellular bud, cytoplasm, molecular_function, ribosome, site of polarized growth",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,23,9.7,no,,,,, P108,4,A4,P108_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL071W,EMI5,SDH5,"Subunit of succinate dehydrogenase, which couples succinate oxidation to ubiquinone reduction; required for FAD cofactor attachment to Sdh1p; mutations in human ortholog PGL2 are associated with neuroendocrine tumors (paraganglioma)","cofactor metabolic process, transcription, generation of precursor metabolites and energy, cellular respiration, sporulation resulting in formation of a cellular spore, RNA metabolic process",oxidoreductase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","RNA metabolic process, mitochondrion, molecular_function, sporulation, transcription",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,24,12.8,no,,,,, P108,5,A5,P108_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL072W,THP1,BUD29,"Nuclear pore-associated protein, forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus; contains a PAM domain implicated in protein-protein binding","transport, cytokinesis, transcription, response to stress, cell cycle, DNA metabolic process, RNA metabolic process","RNA binding, DNA binding","nucleus, endomembrane system, membrane","DNA metabolic process, RNA metabolic process, anatomical structure morphogenesis, cytokinesis, endomembrane system, membrane, nucleus, protein binding, response to stress, transcription, transport",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,64,36.2,no,,,,, P108,6,A6,P108_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL075C,,,Putative ABC transporter,transport,"transporter activity, hydrolase activity",membrane,"hydrolase activity, membrane, transport, transporter activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,60,24.8,no,,,,, P108,7,A7,P108_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL076W,MDM20,NAA25;DEC1,"Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes N-acetylation of proteins with specific N-terminal sequences; involved in mitochondrial inheritance and actin assembly","mitochondrion organization, cytoskeleton organization, protein modification process",transferase activity,cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein modification process, transferase activity",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,64,31.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P108,8,A8,P108_A8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P108,9,A9,P108_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL079W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,6,2.9,no,,,,, P108,10,A10,P108_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL080C,REX4,,Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly,"ribosome biogenesis, RNA metabolic process",hydrolase activity,"nucleus, nucleolus","RNA metabolic process, hydrolase activity, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,28,10.9,no,,,,, P108,11,A11,P108_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL081W,IRA2,GLC4;CCS1,"GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin","response to stress, signaling process, heterocycle metabolic process",enzyme regulator activity,"mitochondrion, cytoplasm","cytoplasm, enzyme regulator activity, mitochondrion, other, response to stress, signal transduction",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,14,6.7,no,,,,, P108,12,A12,P108_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL082W,ATG19,CVT19,Receptor protein specific for the cytoplasm-to-vacuole targeting (Cvt) pathway; delivers cargo proteins aminopeptidase I (Lap4p) and alpha-mannosidase (Ams1p) to the phagophore assembly site for packaging into Cvt vesicles,"transport, vesicle organization, cellular protein catabolic process",protein binding,"membrane fraction, cytoplasm","cytoplasm, membrane fraction, organelle organization and biogenesis, other, protein binding, protein catabolic process, transport",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,13,7.6,no,,,,, P108,13,B1,P108_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL084W,PHM7,,"Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole",biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,22,12.4,no,,,,, P108,14,B2,P108_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL085C,,,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,28,13.6,no,,,,, P108,15,B3,P108_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL274W,SAM3,,"High-affinity S-adenosylmethionine permease, required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,0,0,no,,,,, P108,16,B4,P108_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL273W,SAM4,,"S-adenosylmethionine-homocysteine methyltransferase, functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, nucleus, transferase activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,0,0,no,,,,, P108,17,B5,P108_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL272C,,,Putative protein of unknown function; gene expression induced in response to ketoconazole; YPL272C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,0,0,no,,,,, P108,18,B6,P108_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL270W,MDL2,,"Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, required for respiratory growth at high temperature; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis",transport,"transporter activity, hydrolase activity","membrane, mitochondrial envelope, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, transporter activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,34,11.4,no,,,,, P108,19,B7,P108_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL269W,KAR9,,"Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase",transport,molecular_function,"cell cortex, site of polarized growth, cytoplasm","cell cortex, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis, site of polarized growth, transport",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,2,1,no,,,,, P108,20,B8,P108_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL267W,ACM1,,"Pseudosubstrate inhibitor of the anaphase-promoting complex/cyclosome (APC/C), that suppresses APC/C [Cdh1]-mediated proteolysis of mitotic cyclins; associates with Cdh1p, Bmh1p and Bmh2p; cell cycle regulated protein","cell cycle, protein modification process",enzyme regulator activity,"nucleus, cytoplasm","cell cycle, cytoplasm, enzyme regulator activity, nucleus",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,28,11.1,no,,,,, P108,21,B9,P108_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL265W,DIP5,,"Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,12,5.7,no,,,,, P108,22,B10,P108_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL264C,,,Putative membrane protein of unknown function; physically interacts with Hsp82p; YPL264C is not an essential gene,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,12,3.9,no,,,,, P108,23,B11,P108_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL263C,KEL3,,Cytoplasmic protein of unknown function,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,8,2.5,no,,,,, P108,24,B12,P108_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL262W,FUM1,,"Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",lyase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, lyase activity, mitochondrion, other",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,5,2.5,no,,,,, P108,25,C1,P108_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL260W,,,Putative substrate of cAMP-dependent protein kinase (PKA); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YPL260W is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,4,1.5,no,,,,, P108,26,C2,P108_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL261C,,,Dubious open reading frame unlikely to encode a protein; partially overlaps the uncharacterized ORF YPL260W,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,14,8.2,no,,,,, P108,27,C3,P108_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL259C,APM1,YAP54,Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting,"transport, vesicle-mediated transport",protein binding,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, protein binding, transport, vesicle-mediated transport",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,14,4.5,no,,,,, P108,28,C4,P108_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL258C,THI21,,"Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI20 and THI22; Thi20p also has this activity","vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cellular_component,"cellular_component, transferase activity, vitamin metabolic process",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,18,9.1,no,,,,, P108,29,C5,P108_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL257W,,,Putative protein of unknown function; homozygous diploid deletion strain exhibits low budding index; physically interacts with Hsp82p; YPL257W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,28,8.4,no,,,,, P108,30,C6,P108_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL256C,CLN2,,"G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)","conjugation, cell cycle, response to chemical stimulus",enzyme regulator activity,"nucleus, cytoplasm","DNA metabolic process, cell cycle, conjugation, cytoplasm, enzyme regulator activity, nucleus, other, response to chemical stimulus, signal transduction, transposition",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,13,7.2,no,,,,, P108,31,C7,P108_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL254W,HFI1,GAN1;SRM12;SUP110;ADA1,"Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions","chromosome organization, transcription, protein modification process, RNA metabolic process","transcription regulator activity, protein binding",nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription, transcription regulator activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,227,3,1.3,no,,,,, P108,32,C8,P108_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL253C,VIK1,,"Protein that forms a complex with Kar3p at the spindle pole body, possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; has similarity to Cik1p","chromosome segregation, chromosome organization, cell cycle","motor activity, hydrolase activity","cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, motor activity, organelle organization and biogenesis",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,231,16,6.9,no,,,,, P108,33,C9,P108_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL250C,ICY2,,Protein of unknown function; mobilized into polysomes upon a shift from a fermentable to nonfermentable carbon source; potential Cdc28p substrate,other,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,20,9,no,,,,, P108,34,C10,P108_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL249C,GYP5,,"GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p","transport, vesicle-mediated transport",enzyme regulator activity,"membrane fraction, cellular bud, cytoplasmic membrane-bounded vesicle, membrane, site of polarized growth, Golgi apparatus, cytoplasm, plasma membrane","Golgi apparatus, cellular bud, cytoplasm, cytoplasmic membrane-bounded vesicle, enzyme regulator activity, membrane fraction, other, plasma membrane, site of polarized growth, transport, vesicle-mediated transport",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,2,0.9,no,,,,, P108,35,C11,P108_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL248C,GAL4,GAL81,DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p,"cellular carbohydrate metabolic process, transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, carbohydrate metabolic process, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,152,4,2.6,no,,,,, P108,36,C12,P108_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL247C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; overexpression causes a cell cycle delay or arrest,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,12,4,no,,,,, P108,37,D1,P108_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL246C,RBD2,,"Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p",biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,10,3.6,no,,,,, P108,38,D2,P108_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL245W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,0,0,no,,,,, P108,39,D3,P108_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL244C,HUT1,,"Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1",transport,transporter activity,cellular_component,"cellular_component, transport, transporter activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,10,5,no,,,,, P108,40,D4,P108_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL241C,CIN2,,"GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; deletion complemented by human GAP, retinitis pigmentosa 2",protein folding,enzyme regulator activity,cellular_component,"cellular_component, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, protein folding",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,9,4.7,no,,,,, P108,41,D5,P108_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL240C,HSP82,HSP90,"Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p","transport, mitochondrion organization, protein complex biogenesis, response to stress, protein folding, chromosome organization, DNA metabolic process","hydrolase activity, protein binding",cytoplasm,"DNA metabolic process, cytoplasm, hydrolase activity, organelle organization and biogenesis, other, protein binding, protein folding, response to stress",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,8,3.4,no,,,,, P108,42,D6,P108_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL239W,YAR1,,"Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock","response to stress, ribosome biogenesis, response to chemical stimulus",molecular_function,cytoplasm,"cytoplasm, molecular_function, organelle organization and biogenesis, response to chemical stimulus, response to stress, ribosome biogenesis",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,2,1.1,no,,,,, P108,43,D7,P108_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL236C,,,,biological_process,"transferase activity, protein kinase activity","membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, protein kinase activity, transferase activity, vacuole",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,16,6.2,no,,,,, P108,44,D8,P108_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL234C,TFP3,VMA11;CLS9,"Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,14,8,no,,,,, P108,45,D9,P108_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL232W,SSO1,,Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p,"transport, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cellular membrane organization","lipid binding, protein binding","membrane fraction, vacuole, membrane, cytoplasm, plasma membrane","membrane, membrane organization and biogenesis, plasma membrane, protein binding, sporulation, transport, vesicle-mediated transport",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,4,1.7,no,,,,, P108,46,D10,P108_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL230W,USV1,NSF1,"Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis","response to stress, transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, nucleus, response to chemical stimulus, response to stress, transcription, transcription regulator activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,4,1.8,no,,,,, P108,47,D11,P108_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL229W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL229W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,0,0,no,,,,, P108,48,D12,P108_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL227C,ALG5,,"UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum","cellular carbohydrate metabolic process, protein modification process",transferase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein modification process, transferase activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,5,2.8,no,,,,, P108,49,E1,P108_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL226W,NEW1,,ATP binding cassette protein that cosediments with polysomes and is required for biogenesis of the small ribosomal subunit; Asn/Gln-rich rich region supports [NU+] prion formation and susceptibility to [PSI+] prion induction,"transport, ribosome biogenesis",hydrolase activity,"mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, other, ribosome biogenesis",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,8,2.4,no,,,,, P108,50,E2,P108_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL225W,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,6,2.8,no,,,,, P108,51,E3,P108_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL223C,GRE1,,"Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway",biological_process,molecular_function,cytoplasm,"cytoplasm, molecular_function, response to stress",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,10,4.4,no,,,,, P108,52,E4,P108_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL222W,FMP40,,"Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,2,1,no,,,,, P108,53,E5,P108_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL221W,FLC1,BOP1;HUF1,Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance,"transport, protein folding",transporter activity,"vacuole, cellular bud, site of polarized growth, endoplasmic reticulum, cytoplasm","cell wall organization and biogenesis, cellular bud, cytoplasm, endoplasmic reticulum, protein folding, site of polarized growth, transport, transporter activity, vacuole",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,14,4.2,no,,,,, P108,54,E6,P108_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL220W,RPL1A,L1A;SSM1,"N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,16,5.6,no,,,,, P108,55,E7,P108_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL219W,PCL8,,"Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",enzyme regulator activity,other,"carbohydrate metabolic process, enzyme regulator activity, generation of precursor metabolites and energy, other",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,28,11.4,no,,,,, P108,56,E8,P108_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL216W,,,Putative protein of unknown function; YPL216W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,14,5.4,no,,,,, P108,57,E9,P108_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL214C,THI6,,"Bifunctional enzyme with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities, required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern","vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cytoplasm,"cytoplasm, transferase activity, vitamin metabolic process",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,20,7.1,no,,,,, P108,58,E10,P108_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL213W,LEA1,,Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; putative homolog of human U2A' snRNP protein,RNA metabolic process,molecular_function,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, other",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,216,6,2.8,no,,,,, P108,59,E11,P108_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL212C,PUS1,,"tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA",RNA metabolic process,isomerase activity,nucleus,"RNA metabolic process, isomerase activity, nucleus, ribosome biogenesis",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,1,0.5,no,,,,, P108,60,E12,P108_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL208W,RKM1,,"SET-domain lysine-N-methyltransferase, catalyzes the formation of dimethyllysine residues on the large ribsomal subunit protein L23a (RPL23A and RPL23B)",protein modification process,transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, response to chemical stimulus, transferase activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,4,1.5,no,,,,, P108,61,F1,P108_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL207W,TYW1,,"Protein required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions",RNA metabolic process,molecular_function,"endoplasmic reticulum, cytoplasm","RNA metabolic process, endoplasmic reticulum, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,23,10,no,,,,, P108,62,F2,P108_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL206C,PGC1,,Phosphatidyl Glycerol phospholipase C; regulates the phosphatidylglycerol (PG) content via a phospholipase C-type degradation mechanism; contains glycerophosphodiester phosphodiesterase motifs,cellular lipid metabolic process,hydrolase activity,"mitochondrion, cytoplasm","endoplasmic reticulum, hydrolase activity, lipid metabolic process, mitochondrion",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,24,7.1,no,,,,, P108,63,F3,P108_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL205C,,,Hypothetical protein; deletion of locus affects telomere length,"sporulation resulting in formation of a cellular spore, transcription, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, cellular_component, molecular_function, sporulation, transcription",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,5,2.5,no,,,,, P108,64,F4,P108_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL203W,TPK2,PKA3;YKR1;PKA2,cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase,"signaling process, protein modification process","transferase activity, protein kinase activity",nucleus,"nucleus, other, protein kinase activity, protein modification process, signal transduction, transferase activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,16,5.8,no,,,,, P108,65,F5,P108_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL202C,AFT2,,Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; similar to Aft1p,"transcription, response to chemical stimulus, protein complex biogenesis, response to stress, cellular homeostasis, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, mitochondrion, cytoplasm","DNA binding, RNA metabolic process, cellular homeostasis, mitochondrion, nucleus, response to chemical stimulus, response to stress, transcription, transcription regulator activity",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,14,4.7,no,,,,, P108,66,F6,P108_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL201C,YIG1,,Protein that interacts with glycerol 3-phosphatase and plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol,"cellular carbohydrate metabolic process, generation of precursor metabolites and energy",molecular_function,"nucleus, cytoplasm","cytoplasm, generation of precursor metabolites and energy, molecular_function, nucleus",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,13,5.9,no,,,,, P108,67,F7,P108_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL200W,CSM4,,Protein required for accurate chromosome segregation during meiosis; involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements,"chromosome segregation, meiosis, chromosome organization, cell cycle, DNA metabolic process",molecular_function,"nucleus, endomembrane system, chromosome, membrane, endoplasmic reticulum, cytoplasm","cell cycle, chromosome, cytoplasm, endomembrane system, endoplasmic reticulum, meiosis, membrane, molecular_function, nucleus, organelle organization and biogenesis",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,412,14,3.4,no,,,,, P108,68,F8,P108_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL199C,,,"Putative protein of unknown function, predicted to be palmitoylated",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,8,2.9,no,,,,, P108,69,F9,P108_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL198W,RPL7B,YL8;L7B;L6B;rp11,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)",translation,structural molecule activity,"nucleus, nucleolus, ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,8,2.4,no,,,,, P108,70,F10,P108_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL197C,,,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the ribosomal gene RPB7B",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,4,1.9,no,,,,, P108,71,F11,P108_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL196W,OXR1,,"Protein of unknown function required for normal levels of resistance to oxidative damage, null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes","response to stress, response to chemical stimulus",molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, response to chemical stimulus, response to stress",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,6,1.8,no,,,,, P108,72,F12,P108_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL195W,APL5,YKS4,"Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function","transport, vesicle-mediated transport",protein binding,"membrane, cytoplasm","cytoplasm, membrane, protein binding, transport, vesicle-mediated transport",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,8,3.8,no,,,,, P108,73,G1,P108_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL194W,DDC1,,"DNA damage checkpoint protein, part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate","signaling process, response to stress, meiosis, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleus, response to stress, signal transduction",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,38,21.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P108,74,G2,P108_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL193W,RSA1,,Protein involved in the assembly of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the assembly,ribosome biogenesis,molecular_function,nucleus,"molecular_function, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,4,1.8,no,,,,, P108,75,G3,P108_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL192C,PRM3,,Pheromone-regulated protein required for nuclear envelope fusion during karyogamy; localizes to the outer face of the nuclear membrane; interacts with Kar5p at the spindle pole body,"conjugation, nucleus organization, cellular membrane organization",molecular_function,"nucleus, cytoskeleton, microtubule organizing center, endomembrane system, membrane, cytoplasm","conjugation, endomembrane system, molecular_function, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, response to chemical stimulus",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,36,18.5,no,,,,, P108,76,G4,P108_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL191C,,,Putative protein of unknown function; diploid deletion strain exhibits high budding index; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,28,14.1,no,,,,, P108,77,G5,P108_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL189W,GUP2,,Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog,transport,transferase activity,membrane,"membrane, transferase activity, transport",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,50,15.2,no,,,,, P108,78,G6,P108_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL188W,POS5,,"Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress","response to stress, cofactor metabolic process, vitamin metabolic process, response to chemical stimulus",transferase activity,"mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, mitochondrion, response to chemical stimulus, response to stress, transferase activity, vitamin metabolic process",,,16_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,15,7.7,no,,,,, P108,79,G7,P108_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL187W,MF(ALPHA)1,,"Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor","signaling process, conjugation, response to chemical stimulus",protein binding,extracellular region,"conjugation, extracellular region, protein binding, response to chemical stimulus, signal transduction",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,24,7.8,no,,,,, P108,80,G8,P108_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL185W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene UIP4/YPL186C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,11,5.8,no,,,,, P108,81,G9,P108_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL186C,UIP4,,"Protein that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope",biological_process,molecular_function,"nucleus, membrane, endomembrane system, mitochondrial envelope, mitochondrion, endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, mitochondrial envelope, mitochondrion, molecular_function, nucleus",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,7,3.9,no,,,,, P108,82,G10,P108_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL184C,MRN1,PTR69,"RNA-binding protein proposed to be involved in translational regulation; binds specific categories of mRNAs, including those that contain upstream open reading frames (uORFs) and internal ribosome entry sites (IRES)",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,10,3.1,no,,,,, P108,83,G11,P108_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL181W,CTI6,RXT1,Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain,"chromosome organization, transcription, DNA metabolic process, protein modification process","protein binding, hydrolase activity","nucleus, chromosome","hydrolase activity, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,17,7.9,no,,,,, P108,84,G12,P108_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL182C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CTI6/YPL181W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,6,1.9,no,,,,, P108,85,H1,P108_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL180W,TCO89,,"Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates growth in response to nutrient availability; cooperates with Ssd1p in the maintenance of cellular integrity; deletion strains are hypersensitive to rapamycin","fungal-type cell wall organization, signaling process, response to stress, cellular carbohydrate metabolic process",molecular_function,"vacuole, membrane, cytoplasm, plasma membrane","cell wall organization and biogenesis, cytoplasm, membrane, molecular_function, other, plasma membrane, response to stress, signal transduction, vacuole",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,19,10,no,,,,, P108,86,H2,P108_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL179W,PPQ1,SAL6,Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational suppressors,"translation, protein modification process","phosphoprotein phosphatase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, phosphoprotein phosphatase activity, protein modification process, translation",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,10,5.8,no,,,,, P108,87,H3,P108_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P108,88,H4,P108_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL178W,CBC2,CBP20;SAE1;MUD13,"Small subunit of the heterodimeric cap binding complex that also contains Sto1p, component of the spliceosomal commitment complex; interacts with Npl3p, possibly to package mRNA for export from the nucleus; contains an RNA-binding motif",RNA metabolic process,RNA binding,nucleus,"RNA binding, RNA metabolic process, nucleus, other",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,13,6.4,no,,,,, P108,89,H5,P108_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL177C,CUP9,,"Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription","transcription, cellular homeostasis, protein complex biogenesis, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, cellular homeostasis, nucleus, transcription, transcription regulator activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,30,10.3,no,,,,, P108,90,H6,P108_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL176C,TRE1,,Plasma membrane protein that binds to Bsd2p and regulates ubiquitylation and vacuolar degradation of the metal transporter Smf1p; function is redundant with that of Tre2p; has similarity to transferrin receptors,"transport, vesicle-mediated transport, cellular protein catabolic process",molecular_function,"vacuole, cytoplasm","molecular_function, plasma membrane, protein catabolic process",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,19,10.1,no,,,,, P108,91,H7,P108_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL174C,NIP100,PAC13,"Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)","cytoskeleton organization, cell cycle",protein binding,"cell cortex, cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, organelle organization and biogenesis, protein binding",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,0,0,no,,,,, P108,92,H8,P108_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL171C,OYE3,Old Yellow Enzyme;ZRG6,"Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with different ligand binding and catalytic properties; has potential roles in oxidative stress response and programmed cell death",other,oxidoreductase activity,cellular_component,"cellular_component, oxidoreductase activity, response to chemical stimulus",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,289,0,0,no,,,,, P108,93,H9,P108_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL170W,DAP1,,"Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis",other,other,"membrane, cytoplasm","lipid metabolic process, membrane, other",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,6,2.1,no,,,,, P108,94,H10,P108_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL168W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; expression may be cell cycle-regulated,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,0,0,no,,,,, P108,95,H11,P108_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL167C,REV3,PSO1,"Catalytic subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair","response to stress, DNA metabolic process","transferase activity, nucleotidyltransferase activity","nucleus, chromosome, mitochondrion, cytoplasm","DNA metabolic process, mitochondrion, nucleotidyltransferase activity, other, response to stress, transferase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,28,12.6,no,,,,, P108,96,H12,P108_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL166W,ATG29,,Autophagy-specific protein that is required for recruitment of other ATG proteins to the pre-autophagosomal structure (PAS); interacts with Atg17p and localizas to the PAS in a manner interdependent with Atg17p and Cis1p; not conserved,"response to stress, cellular membrane organization",molecular_function,cytoplasm,"cytoplasm, membrane organization and biogenesis, molecular_function, response to stress",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,0,0,no,,,,, P109,1,A1,P109_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL165C,SET6,,"SET domain protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,229,8,3.5,no,,,,, P109,2,A2,P109_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL164C,MLH3,,Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability,"response to stress, meiosis, cell cycle, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, cell cycle, meiosis, molecular_function, nucleus, response to stress",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,8,3.1,no,,,,, P109,3,A3,P109_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL163C,SVS1,,"Cell wall and vacuolar protein, required for wild-type resistance to vanadate",response to chemical stimulus,molecular_function,"cell wall, vacuole, cytoplasm","cell wall, cytoplasm, molecular_function, response to chemical stimulus, vacuole",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,10,3,no,,,,, P109,4,A4,P109_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL162C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology,biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,24,10.9,no,,,,, P109,5,A5,P109_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL161C,BEM4,ROM7,Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length,"signaling process, cytoskeleton organization",molecular_function,"nucleus, cytoplasm","DNA metabolic process, anatomical structure morphogenesis, cytoplasm, cytoskeleton organization and biogenesis, molecular_function, nucleus, organelle organization and biogenesis, signal transduction, transposition",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,8,3.7,no,,,,, P109,6,A6,P109_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL159C,PET20,,"Mitochondrial protein, required for respiratory growth under some conditions and for stability of the mitochondrial genome","generation of precursor metabolites and energy, cellular respiration",molecular_function,"mitochondrion, cytoplasm","cellular respiration, generation of precursor metabolites and energy, mitochondrion, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,5,2.9,no,,,,, P109,7,A7,P109_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL157W,TGS1,,"Trimethyl guanosine synthase, conserved nucleolar methyl transferase that converts the m(7)G cap structure of snRNAs, snoRNAs, and telomerase TLC1 RNA to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology","chromosome organization, ribosome biogenesis, DNA metabolic process, RNA metabolic process, nucleus organization",transferase activity,"nucleus, nucleolus","RNA metabolic process, nuclear organization and biogenesis, nucleolus, organelle organization and biogenesis, ribosome biogenesis, transferase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,154,8,5.2,no,,,,, P109,8,A8,P109_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL156C,PRM4,,Pheromone-regulated protein proposed to be involved in mating; predicted to have 1 transmembrane segment; transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift,biological_process,molecular_function,membrane,"conjugation, membrane, molecular_function, response to chemical stimulus",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,4,1.8,no,,,,, P109,9,A9,P109_A9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P109,10,A10,P109_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL155C,KIP2,,"Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle","transport, cytoskeleton organization, cell cycle","motor activity, hydrolase activity","cytoskeleton, mitochondrion, cytoplasm","cell cycle, cytoskeleton, cytoskeleton organization and biogenesis, mitochondrion, motor activity, organelle organization and biogenesis, transport",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,18,8.5,no,,,,, P109,11,A11,P109_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL154C,PEP4,yscA;PRA1;PHO9,"Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates","response to stress, sporulation resulting in formation of a cellular spore, cellular membrane organization, cellular protein catabolic process","peptidase activity, hydrolase activity","vacuole, mitochondrion, cytoplasm","cytoplasm, membrane organization and biogenesis, mitochondrion, peptidase activity, protein catabolic process, response to stress, sporulation, vacuole",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,14,6.5,no,,,,, P109,12,A12,P109_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL152W,RRD2,YPA2,"Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex","response to stress, cytoskeleton organization, cell cycle","isomerase activity, enzyme regulator activity",cytoplasm,"cell cycle, cytoplasm, cytoskeleton organization and biogenesis, enzyme regulator activity, isomerase activity, organelle organization and biogenesis, other, response to stress",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,437,89,20.4,no,,,,, P109,13,B1,P109_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL150W,,,Putative protein kinase of unknown cellular role,biological_process,"transferase activity, protein kinase activity",cellular_component,"biological_process, cellular_component, protein kinase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,12,4.5,no,,,,, P109,14,B2,P109_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL149W,ATG5,APG5,Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; conjugated Atg12p also forms a complex with Atg16p that is essential for autophagosome formation,"transport, response to stress, protein modification process, cellular membrane organization",ligase activity,"vacuole, cytoplasm","cytoplasm, ligase activity, membrane organization and biogenesis, protein modification process, response to stress, transport, vacuole",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,18,5.9,no,,,,, P109,15,B3,P109_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL147W,PXA1,SSH2;PAT2;PAL1;LPI1,"Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins",transport,"transporter activity, hydrolase activity","peroxisome, membrane, cytoplasm","cytoplasm, hydrolase activity, membrane, peroxisome, transport, transporter activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,8,3,no,,,,, P109,16,B4,P109_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL145C,KES1,BSR3;OSH4;LPI3,"Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex","transport, vesicle-mediated transport, cellular membrane organization","lipid binding, transporter activity","endomembrane system, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, anatomical structure morphogenesis, cytoplasm, endomembrane system, lipid binding, membrane, membrane organization and biogenesis, transport, vesicle-mediated transport",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,16,6.2,no,,,,, P109,17,B5,P109_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL144W,POC4,DMP1;PBA4,Component of a heterodimeric Poc4p-Irc25p chaperone involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions,protein complex biogenesis,molecular_function,cytoplasm,"cytoplasm, molecular_function, other",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,8,4.1,no,,,,, P109,18,B6,P109_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL141C,FRK1,,Putative protein kinase; similar to Kin4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; interacts with rRNA transcription and ribosome biogenesis factors and the long chain fatty acyl-CoA synthetase Faa3,biological_process,"transferase activity, protein kinase activity",cytoplasm,"biological_process, cytoplasm, protein kinase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,5,2.7,no,,,,, P109,19,B7,P109_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL140C,MKK2,SSP33;LPI6,"Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p","signaling process, peroxisome organization, protein modification process","transferase activity, protein kinase activity",other,"other, protein kinase activity, protein modification process, signal transduction, transferase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,8,4.2,no,,,,, P109,20,B8,P109_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL139C,UME1,WTM3,"Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p","transcription, protein modification process, meiosis, chromosome organization, cell cycle, RNA metabolic process","transcription regulator activity, hydrolase activity, protein binding","nucleus, chromosome","cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription regulator activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,6,3.4,no,,,,, P109,21,B9,P109_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL138C,SPP1,SAF41;CPS40,"Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; interacts with Orc2p; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein","chromosome organization, transcription, protein modification process, RNA metabolic process","transferase activity, protein binding",nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription, transferase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,8,4.5,no,,,,, P109,22,B10,P109_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL136W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene GIP3/YPL137C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,10,4.2,no,,,,, P109,23,B11,P109_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL135W,ISU1,NUA1,"Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable","cofactor metabolic process, cellular homeostasis, RNA metabolic process",other,"mitochondrion, cytoplasm","cellular homeostasis, cofactor metabolic process, cytoplasm, mitochondrion, protein binding",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,4,1.8,no,,,,, P109,24,B12,P109_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL133C,RDS2,,Zinc cluster transcriptional activator involved in conferring resistance to ketoconazole,"cellular carbohydrate metabolic process, response to chemical stimulus","transcription regulator activity, DNA binding","nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, nucleus, response to chemical stimulus, transcription regulator activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,5,2.7,no,,,,, P109,25,C1,P109_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL130W,SPO19,,Meiosis-specific prospore protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; identified as a weak high-copy suppressor of the spo1-1 ts mutation,"meiosis, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cell cycle, cellular membrane organization",molecular_function,"cell wall, membrane","cell wall, meiosis, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,22,11.6,no,,,,, P109,26,C2,P109_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL129W,TAF14,TafII30;ANC1;TFG3;TAF30;SWP29,"Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain","transcription, protein modification process, protein complex biogenesis, chromosome organization, RNA metabolic process","transcription regulator activity, transferase activity","nucleus, chromosome","RNA metabolic process, cell cycle, nucleus, organelle organization and biogenesis, protein modification process, transcription, transcription regulator activity, transferase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,10,6,no,,,,, P109,27,C3,P109_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL127C,HHO1,,"Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation","transcription, DNA metabolic process, RNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, RNA metabolic process, chromosome, nucleus, transcription",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,10,5.1,no,,,,, P109,28,C4,P109_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL125W,KAP120,,Karyopherin responsible for the nuclear import of ribosome maturation factor Rfp1p,transport,structural molecule activity,"nucleus, membrane, endomembrane system, cytoplasm","cytoplasm, endomembrane system, membrane, nucleus, structural molecule activity, transport",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,9,3.8,no,,,,, P109,29,C5,P109_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL123C,RNY1,,"Vacuolar RNase of the T(2) family, relocalizes to the cytosol where it cleaves tRNAs upon oxidative or stationary phase stress; promotes apoptosis under stress conditions and this function is independent of its catalytic activity","cellular component morphogenesis, RNA metabolic process",hydrolase activity,"extracellular region, vacuole, cytoplasm","anatomical structure morphogenesis, extracellular region, hydrolase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,12,6.3,no,,,,, P109,30,C6,P109_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL121C,MEI5,LPH6,"Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p","response to stress, meiosis, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleus, response to stress",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,2,1.2,no,,,,, P109,31,C7,P109_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL120W,VPS30,ATG6;VPT30;APG6,Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy and Complex II is required for vacuolar protein sorting; ortholog of the higher eukaryotic gene Beclin 1,"transport, response to stress, vesicle-mediated transport, cellular lipid metabolic process, cellular membrane organization, cellular protein catabolic process",transferase activity,"membrane fraction, cytoplasm","cytoplasm, lipid metabolic process, membrane fraction, membrane organization and biogenesis, protein catabolic process, response to stress, transferase activity, transport, vesicle-mediated transport",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,18,9.3,no,,,,, P109,32,C8,P109_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL119C,DBP1,LPH8,Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs,translation,"helicase activity, hydrolase activity",cytoplasm,"cytoplasm, helicase activity, translation",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,20,6.8,no,,,,, P109,33,C9,P109_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL118W,MRP51,,Mitochondrial ribosomal protein of the small subunit; MRP51 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,6,2.8,no,,,,, P109,34,C10,P109_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL116W,HOS3,,"Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats","transcription, protein modification process, chromosome organization, cell cycle, RNA metabolic process",hydrolase activity,"nucleus, cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoplasm, hydrolase activity, nucleus, organelle organization and biogenesis, protein modification process, site of polarized growth",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,6,2.6,no,,,,, P109,35,C11,P109_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL115C,BEM3,,"Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly","cell budding, signaling process, pseudohyphal growth","lipid binding, enzyme regulator activity","cellular bud, cell cortex, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, enzyme regulator activity, lipid binding, other, pseudohyphal growth, signal transduction",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,14,6.4,no,,,,, P109,36,C12,P109_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL114W,,,"Dubious open reading frame, unlikely to encode a functional protein; largely overlaps ORF YPL113C; diploid deletion in BY4743 strain background exhibits high budding index",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,8,2.7,no,,,,, P109,37,D1,P109_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL113C,,,Glyoxylate reductase; acts on glyoxylate and hydroxypyruvate substrates; YPL113C is not an essential gene,other,oxidoreductase activity,cellular_component,"cellular_component, other, oxidoreductase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,10,4.2,no,,,,, P109,38,D2,P109_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL112C,PEX25,,"Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p","transport, peroxisome organization",molecular_function,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, molecular_function, organelle organization and biogenesis, peroxisome, transport",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,28,9,no,,,,, P109,39,D3,P109_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL111W,CAR1,cargA;LPH15,"Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance",cellular amino acid and derivative metabolic process,"hydrolase activity, enzyme regulator activity","nucleus, site of polarized growth, cytoplasm","amino acid and derivative metabolic process, cytoplasm, hydrolase activity, other",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,8,4.4,no,,,,, P109,40,D4,P109_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL110C,GDE1,,"Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes",cellular lipid metabolic process,hydrolase activity,"ribosome, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, ribosome",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,6,3.2,no,,,,, P109,41,D5,P109_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL109C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,4,1.6,no,,,,, P109,42,D6,P109_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL108W,,,Cytoplasmic protein of unknown function; non-essential gene that is induced in a GDH1 deleted strain with altered redox metabolism; GFP-fusion protein is induced in response to the DNA-damaging agent MMS,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,0,0,no,,,,, P109,43,D7,P109_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL107W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YPL107W is not an essential gene,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,20,5.9,no,,,,, P109,44,D8,P109_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL106C,SSE1,MSI3;LPG3,ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm,protein folding,enzyme regulator activity,cytoplasm,"cytoplasm, other, protein folding",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,2,1,no,,,,, P109,45,D9,P109_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL105C,SYH1,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"ribosome, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function, ribosome",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,22,6.6,no,,,,, P109,46,D10,P109_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL103C,FMP30,,Protein of unknown function proposed to be involved in N-acylethanolamine metabolism; related to human NAPE-selective phospholipase D enzyme; native protein is detected in highly purified mitochondria in high-throughput studies,"cellular lipid metabolic process, cellular amino acid and derivative metabolic process",hydrolase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,4,1.5,no,,,,, P109,47,D11,P109_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL101W,ELP4,KTI9;TOT7;HAP1,"Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity","transcription, RNA metabolic process",molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, other, transcription",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,4,1.3,no,,,,, P109,48,D12,P109_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL102C,,,"Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene ELP4",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,26,8.7,no,,,,, P109,49,E1,P109_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL100W,ATG21,HSV1;MAI1,"Phosphoinositide binding protein required for vesicle formation in the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein","transport, vesicle organization, protein modification process, response to stress, cellular membrane organization",lipid binding,"vacuole, membrane, cytoplasm","cytoplasm, lipid binding, membrane, membrane organization and biogenesis, organelle organization and biogenesis, other, protein modification process, response to stress, transport, vacuole",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,5,2.7,no,,,,, P109,50,E2,P109_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL099C,AIM43,FMP14,"Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,22,7.2,no,,,,, P109,51,E3,P109_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL098C,MGR2,,Protein required for growth of cells lacking the mitochondrial genome,mitochondrion organization,molecular_function,cellular_component,"cellular_component, molecular_function, organelle organization and biogenesis",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,12,5.9,no,,,,, P109,52,E4,P109_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL097W,MSY1,,Mitochondrial tyrosyl-tRNA synthetase,"mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,12,5,no,,,,, P109,53,E5,P109_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL096W,PNG1,,Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p,"protein modification process, cellular protein catabolic process",hydrolase activity,"nucleus, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, nucleus, protein catabolic process, protein modification process",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,8,2.5,no,,,,, P109,54,E6,P109_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL095C,EEB1,,Acyl-coenzymeA:ethanol O-acyltransferase responsible for the major part of medium-chain fatty acid ethyl ester biosynthesis during fermentation; possesses short-chain esterase activity; may be involved in lipid metabolism and detoxification,cellular lipid metabolic process,"transferase activity, hydrolase activity",cellular_component,"cellular_component, hydrolase activity, lipid metabolic process, transferase activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,28,11.1,no,,,,, P109,55,E7,P109_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL092W,SSU1,LPG16,Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux; major facilitator superfamily protein,transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,16_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,16,5.6,no,,,,, P109,56,E8,P109_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR173C,UMP1,RNS2,Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly,"response to stress, protein complex biogenesis, cellular protein catabolic process",molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, other, protein catabolic process, response to stress",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,0,0,no,,,,, P109,57,E9,P109_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR174C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YBR175W; null mutant is viable and sporulation defective",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,18,5.6,no,,,,, P109,58,E10,P109_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR175W,SWD3,SAF35;CPS30,"Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5","chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process",transferase activity,nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,0,0,no,,,,, P109,59,E11,P109_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR176W,ECM31,,"Ketopantoate hydroxymethyltransferase, required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate","cofactor metabolic process, cellular amino acid and derivative metabolic process",transferase activity,"mitochondrion, cytoplasm","cofactor metabolic process, mitochondrion, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,8,2.4,no,,,,, P109,60,E12,P109_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR177C,EHT1,,Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane,cellular lipid metabolic process,"transferase activity, hydrolase activity","membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, membrane, mitochondrial envelope, mitochondrion, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,0,0,no,,,,, P109,61,F1,P109_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR178W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR177C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,1,0.5,no,,,,, P109,62,F2,P109_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR180W,DTR1,,"Putative dityrosine transporter, required for spore wall synthesis; expressed during sporulation; member of the major facilitator superfamily (DHA1 family) of multidrug resistance transporters","transport, sporulation resulting in formation of a cellular spore, cellular component morphogenesis",transporter activity,membrane,"cell wall organization and biogenesis, membrane, sporulation, transport, transporter activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,1,0.5,no,,,,, P109,63,F3,P109_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR181C,RPS6B,RPS102;RPS101;LPG18,Protein component of the small (40S) ribosomal subunit; identical to Rps6Ap and has similarity to rat S6 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,0,0,no,,,,, P109,64,F4,P109_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR182C,SMP1,,Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors,"response to stress, transcription, RNA metabolic process",DNA binding,"nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, nucleus, response to stress, transcription, transcription regulator activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,2,1,no,,,,, P109,65,F5,P109_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR183W,YPC1,alkaline ceramidase,"Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance",cellular lipid metabolic process,"transferase activity, hydrolase activity","endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, lipid metabolic process",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,2,0.7,no,,,,, P109,66,F6,P109_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR184W,,,Putative protein of unknown function; YBR184W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,6,2.1,no,,,,, P109,67,F7,P109_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR185C,MBA1,,Membrane-associated mitochondrial ribosome receptor; involved in assembly of mitochondrial respiratory complexes; may act as a receptor for proteins destined for export from the mitochondrial matrix to the inner membrane,"mitochondrion organization, generation of precursor metabolites and energy, cellular respiration, cellular membrane organization",other,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,4,1.8,no,,,,, P109,68,F8,P109_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR186W,PCH2,,"Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA","meiosis, cell cycle",molecular_function,"nucleus, nucleolus","cell cycle, meiosis, molecular_function, nucleolus",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,2,0.7,no,,,,, P109,69,F9,P109_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR187W,GDT1,,Putative protein of unknown function; expression is reduced in a gcr1 null mutant; GFP-fusion protein localizes to the vacuole; expression pattern and physical interactions suggest a possible role in ribosome biogenesis,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,4,1.9,no,,,,, P109,70,F10,P109_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR188C,NTC20,,"Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs",RNA metabolic process,other,nucleus,"RNA metabolic process, nucleus, other",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,358,0,0,no,,,,, P109,71,F11,P109_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR194W,AIM4,SOY1,"Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,2,0.8,no,,,,, P109,72,F12,P109_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR195C,MSI1,CAC3,"Subunit of chromatin assembly factor I (CAF-1), negative regulator of the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46","response to stress, signaling process, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, response to stress, signal transduction, transcription, transcription regulator activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,6,3.3,no,,,,, P109,73,G1,P109_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR197C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR197C is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,5,2.2,no,,,,, P109,74,G2,P109_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR199W,KTR4,,Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family,"cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, protein modification process, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,6,3,no,,,,, P109,75,G3,P109_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR200W,BEM1,SRO1,"Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p","conjugation, cellular component morphogenesis, response to chemical stimulus","protein binding, lipid binding","cellular bud, site of polarized growth","anatomical structure morphogenesis, cellular bud, conjugation, lipid binding, other, protein binding, response to chemical stimulus, site of polarized growth",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,3,1.1,no,,,,, P109,76,G4,P109_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR201W,DER1,,"Endoplasmic reticulum membrane protein, required for ER-associated protein degradation of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p",cellular protein catabolic process,protein binding,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein binding, protein catabolic process",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,231,0,0,no,,,,, P109,77,G5,P109_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR203W,COS111,,"Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",signaling process,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, signal transduction",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,6,2.5,no,,,,, P109,78,G6,P109_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR204C,,,Serine hydrolase; YBR204C is not an essential gene,biological_process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,4,1.6,no,,,,, P109,79,G7,P109_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR205W,KTR3,,"Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family","fungal-type cell wall organization, cellular carbohydrate metabolic process, protein modification process",transferase activity,membrane fraction,"cell wall organization and biogenesis, membrane fraction, protein modification process, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,0,0,no,,,,, P109,80,G8,P109_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR206W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene KTR3",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,8,2.6,no,,,,, P109,81,G9,P109_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR207W,FTH1,,Putative high affinity iron transporter involved in transport of intravacuolar stores of iron; forms complex with Fet5p; expression is regulated by iron; proposed to play indirect role in endocytosis,"transport, vesicle-mediated transport, cellular membrane organization",transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, transport, transporter activity, vacuole, vesicle-mediated transport",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,4,1.3,no,,,,, P109,82,G10,P109_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR208C,"DUR1,2",DUR80,"Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation",heterocycle metabolic process,"ligase activity, hydrolase activity",cytoplasm,"cytoplasm, heterocycle metabolic process, hydrolase activity, ligase activity, other",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,2,1,no,,,,, P109,83,G11,P109_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR209W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR209W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,4,1.3,no,,,,, P109,84,G12,P109_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR210W,ERV15,,"Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p","transport, cell budding, cytokinesis, vesicle-mediated transport, cell cycle",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm","Golgi apparatus, anatomical structure morphogenesis, cell budding, cytokinesis, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, transport, vesicle-mediated transport",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,3,1.7,no,,,,, P109,85,H1,P109_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR212W,NGR1,RBP1,RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; expressed in stationary phase,"mitochondrion organization, RNA metabolic process",RNA binding,cytoplasm,"DNA binding, RNA binding, cytoplasm, organelle organization and biogenesis, other, translation regulator activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,3,1.7,no,,,,, P109,86,H2,P109_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR213W,MET8,,"Bifunctional dehydrogenase and ferrochelatase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis","cofactor metabolic process, heterocycle metabolic process","lyase activity, oxidoreductase activity",cellular_component,"cellular_component, cofactor metabolic process, heterocycle metabolic process, lyase activity, other, oxidoreductase activity, response to chemical stimulus",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,1,0.4,no,,,,, P109,87,H3,P109_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P109,88,H4,P109_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR214W,SDS24,,"One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; involved in cell separation during budding; may play an indirect role in fluid-phase endocytosis","transport, vesicle-mediated transport, cytokinesis, cellular membrane organization",molecular_function,cytoplasm,"cytoplasm, membrane organization and biogenesis, molecular_function, transport, vesicle-mediated transport",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,4,1.5,no,,,,, P109,89,H5,P109_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR215W,HPC2,,"Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; mutants display synthetic defects with subunits of FACT, a complex that allows passage of RNA Pol II through nucleosomes","chromosome organization, transcription, cell cycle, RNA metabolic process",DNA binding,nucleus,"DNA binding, RNA metabolic process, cell cycle, nucleus, organelle organization and biogenesis, other, transcription",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,4,1.3,no,,,,, P109,90,H6,P109_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR216C,YBP1,,"Protein required for oxidation of specific cysteine residues of the transcription factor Yap1p, resulting in the nuclear localization of Yap1p in response to stress","response to stress, response to chemical stimulus",molecular_function,cytoplasm,"cytoplasm, molecular_function, response to chemical stimulus, response to stress",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,3,1.7,no,,,,, P109,91,H7,P109_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR217W,ATG12,APG12,Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p also forms a complex with Atg16p that is required for autophagosome formation,"transport, response to stress, protein modification process, cellular membrane organization",ligase activity,"membrane fraction, cytoplasm","cytoplasm, ligase activity, membrane fraction, membrane organization and biogenesis, other, response to stress, transport",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,6,3.1,no,,,,, P109,92,H8,P109_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR218C,PYC2,,"Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis","cofactor metabolic process, cellular carbohydrate metabolic process",ligase activity,cytoplasm,"carbohydrate metabolic process, cofactor metabolic process, cytoplasm, ligase activity, vitamin metabolic process",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,6,2.4,no,,,,, P109,93,H9,P109_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR219C,,,Putative protein of unknown function; YBR219C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,4,1.7,no,,,,, P109,94,H10,P109_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR220C,,,Putative protein of unknown function; YBR220C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,4,1.8,no,,,,, P109,95,H11,P109_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR221C,PDB1,,"E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria",cofactor metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,0,0,no,,,,, P109,96,H12,P109_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR222C,PCS60,FAT2,"Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase",biological_process,other,"peroxisome, membrane, cytoplasm","biological_process, cytoplasm, membrane, other, peroxisome",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,4,2.3,no,,,,, P110,1,A1,P110_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR223C,TDP1,,"Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3' and 5'-phosphotyrosyl bonds, involved in the repair of DNA lesions created by topoisomerase I and topoisomerase II; mutations in human homolog result in the neurodegenerative disease SCANI","response to stress, DNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, hydrolase activity, nucleus, response to stress",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,0,0,no,,,,, P110,2,A2,P110_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR224W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TDP1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,6,2.2,no,,,,, P110,3,A3,P110_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR225W,,,Putative protein of unknown function; non-essential gene identified in a screen for mutants affected in mannosylphophorylation of cell wall components,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,3,1.6,no,,,,, P110,4,A4,P110_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR226C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YBR225W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,3,1.6,no,,,,, P110,5,A5,P110_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR227C,MCX1,,Mitochondrial matrix protein; putative ATP-binding chaperone with non-proteolytic function; similar to bacterial ClpX proteins,protein folding,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, other, protein binding",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,3,1.7,no,,,,, P110,6,A6,P110_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR228W,SLX1,,"Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p","response to stress, DNA metabolic process",hydrolase activity,"nucleus, chromosome","DNA metabolic process, chromosome, hydrolase activity, nucleus, response to stress",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,1,0.4,no,,,,, P110,7,A7,P110_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR229C,ROT2,GLS2,"Glucosidase II catalytic subunit required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations",other,hydrolase activity,"mitochondrion, endoplasmic reticulum, cytoplasm","cell wall organization and biogenesis, cytoplasm, endoplasmic reticulum, hydrolase activity, mitochondrion",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,3,1.7,no,,,,, P110,8,A8,P110_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR230C,OM14,,Integral mitochondrial outer membrane protein; abundance is decreased in cells grown in glucose relative to other carbon sources; appears to contain 3 alpha-helical transmembrane segments; ORF encodes a 97-basepair intron,biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, biological_process, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,3,1.2,no,,,,, P110,9,A9,P110_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR231C,SWC5,AOR1,"Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A",chromosome organization,molecular_function,"nucleus, chromosome","molecular_function, nucleus, organelle organization and biogenesis",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,2,0.8,no,,,,, P110,10,A10,P110_A10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P110,11,A11,P110_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR233W,PBP2,HEK1,"RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,3,1.7,no,,,,, P110,12,A12,P110_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR235W,,,"Putative ion transporter, similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family; YBR235W is not an essential gene",transport,transporter activity,cellular_component,"biological_process, cellular_component, transporter activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,8,4.2,no,,,,, P110,13,B1,P110_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR238C,,,Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span,"generation of precursor metabolites and energy, cellular respiration",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cellular respiration, cytoplasm, endomembrane system, generation of precursor metabolites and energy, membrane, mitochondrion, molecular_function, ribosome biogenesis",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,0,0,no,,,,, P110,14,B2,P110_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR239C,ERT1,,"Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition",biological_process,DNA binding,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,251,2,0.8,no,,,,, P110,15,B3,P110_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR240C,THI2,phoF;PHO6,"Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes","transcription, vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity, vitamin metabolic process",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,4,1.3,no,,,,, P110,16,B4,P110_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR241C,,,"Putative transporter, member of the sugar porter family; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; YBR241C is not an essential gene",transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,0,0,no,,,,, P110,17,B5,P110_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR242W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR242W is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,0,0,no,,,,, P110,18,B6,P110_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR244W,GPX2,AMI1,Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress,"response to stress, response to chemical stimulus",oxidoreductase activity,"nucleus, cytoplasm","cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,2,0.8,no,,,,, P110,19,B7,P110_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR245C,ISW1,SGN2,"Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation","chromosome organization, transcription, RNA metabolic process","DNA binding, hydrolase activity",nucleus,"RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, transcription",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,0,0,no,,,,, P110,20,B8,P110_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR246W,RRT2,,Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; null mutants display a weak carboxypeptidase Y missorting/secretion phenotype,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,2,1.1,no,,,,, P110,21,B9,P110_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR248C,HIS7,,"Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor","cellular amino acid and derivative metabolic process, heterocycle metabolic process",transferase activity,other,"amino acid and derivative metabolic process, other, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,2,1.2,no,,,,, P110,22,B10,P110_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR249C,ARO4,,"3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, nucleus, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,2,0.9,no,,,,, P110,23,B11,P110_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR250W,SPO23,,Protein of unknown function; associates with meiosis-specific protein Spo1p,"meiosis, cell cycle",molecular_function,cellular_component,"cellular_component, meiosis, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,3,1.5,no,,,,, P110,24,B12,P110_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR255W,MTC4,,"Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; mtc4 is synthetically sick with cdc13-1",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,1,0.4,no,,,,, P110,25,C1,P110_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR258C,SHG1,CPS15,"Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres","chromosome organization, protein modification process",transferase activity,nucleus,"nucleus, organelle organization and biogenesis, protein modification process, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,6,1.8,no,,,,, P110,26,C2,P110_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR259W,,,Putative protein of unknown function; YBR259W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,0,0,no,,,,, P110,27,C3,P110_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR260C,RGD1,,"GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization","response to chemical stimulus, response to stress","lipid binding, enzyme regulator activity","cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","cell cortex, cellular bud, cytoplasm, cytoskeleton, enzyme regulator activity, response to chemical stimulus, response to stress, signal transduction",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,8,2.4,no,,,,, P110,28,C4,P110_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR261C,TAE1,NTM1,AdoMet-dependent proline methyltransferase; catalyzes the dimethylation of ribosomal proteins Rpl12 and Rps25 at N-terminal proline residues; has a role in protein synthesis; fusion protein localizes to the cytoplasm,"translation, protein modification process",transferase activity,cytoplasm,"biological_process, cytoplasm, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,2,0.8,no,,,,, P110,29,C5,P110_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR262C,AIM5,FMP51,"Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,316,7,2.2,no,,,,, P110,30,C6,P110_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR263W,SHM1,TMP3;SHMT1,"Mitochondrial serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis; reverse reaction generates serine",cellular amino acid and derivative metabolic process,transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, other, transferase activity",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,3,1.3,no,,,,, P110,31,C7,P110_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR264C,YPT10,,Rab family GTP-binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles,other,hydrolase activity,cytoplasm,"cytoplasm, hydrolase activity, organelle organization and biogenesis, other",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,271,0,0,no,,,,, P110,32,C8,P110_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR266C,SLM6,,Protein with a potential role in actin cytoskeleton organization; gene exhibits synthetic genetic interaction with MSS4 encoding phosphatidylinositol 4-phosphate kinase,"transport, vesicle-mediated transport, cellular membrane organization",molecular_function,cellular_component,"cellular_component, membrane organization and biogenesis, molecular_function, transport, vesicle-mediated transport",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,303,0,0,no,,,,, P110,33,C9,P110_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR267W,REI1,,"Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network","transport, cell budding, ribosome biogenesis, cell cycle",DNA binding,"ribosome, cytoplasm","cell budding, cell cycle, cytoplasm, molecular_function, organelle organization and biogenesis, ribosome, ribosome biogenesis, transport",,,02_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,275,4,1.5,no,,,,, P110,34,C10,P110_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR049W,,,Zinc finger protein; putative transcription factor that may interact with proteins involved in histone acetylation or deacetylation; may be involved in altering acetylation on histone lysines,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,24,9.8,no,,,,, P110,35,C11,P110_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR051C,DET1,,Acid phosphatase involved in the non-vesicular transport of sterols in both directions between the endoplasmic reticulum and plasma membrane; deletion confers sensitivity to nickel,transport,hydrolase activity,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,22,9,no,,,,, P110,36,C12,P110_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR055W,PST1,HPF2,"Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1",fungal-type cell wall organization,molecular_function,"cell wall, membrane, plasma membrane","cell wall, cell wall organization and biogenesis, molecular_function, plasma membrane, response to chemical stimulus",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,33,14.5,no,,,,, P110,37,D1,P110_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR056C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic retiuculum; YDR056C is not an essential protein,biological_process,molecular_function,"membrane fraction, endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, membrane fraction, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,9,4.4,no,,,,, P110,38,D2,P110_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR057W,YOS9,,"ER quality-control lectin; integral subunit of the HRD ligase; binds to glycans with terminal alpha-1,6 linked mannose on misfolded N-glycosylated proteins and participates in targeting proteins to ERAD; member of the OS-9 protein family",cellular protein catabolic process,other,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, other, protein catabolic process",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,46,15.2,no,,,,, P110,39,D3,P110_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR059C,UBC5,,"Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible","response to stress, protein modification process",ligase activity,other,"ligase activity, membrane organization and biogenesis, other, protein modification process, response to chemical stimulus, response to stress, sporulation, transport, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,10,3.5,no,,,,, P110,40,D4,P110_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR061W,,,Protein with similarity to ATP-binding cassette (ABC) transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,10,4.5,no,,,,, P110,41,D5,P110_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR063W,AIM7,GMF1;GMF;Glia maturation factor,Protein that interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss,"cytoskeleton organization, protein complex biogenesis",molecular_function,"nucleus, cell cortex, cytoskeleton, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,23,10.6,no,,,,, P110,42,D6,P110_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR065W,RRG1,,"Protein of unknown function, required for vacuolar acidification and mitochondrial genome maintenance; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","mitochondrion organization, cellular homeostasis",molecular_function,"mitochondrion, cytoplasm","cellular homeostasis, mitochondrion, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,54,17.9,no,,,,, P110,43,D7,P110_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR066C,RTR2,,Protein of unknown function with high similarity to Rtr1p; exhibits genetic interactions with Rtr1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR066C is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,10,4,no,,,,, P110,44,D8,P110_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR067C,OCA6,,"Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,7,3.1,no,,,,, P110,45,D9,P110_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR068W,DOS2,,"Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,256,21,8.2,no,,,,, P110,46,D10,P110_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR069C,DOA4,UBP4;SSV7;NPI2;MUT4;DOS1,"Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole","transport, protein modification process, vesicle-mediated transport, DNA metabolic process, cellular homeostasis, cellular protein catabolic process, cellular membrane organization","peptidase activity, hydrolase activity","membrane fraction, mitochondrion, cytoplasm","DNA metabolic process, cytoplasm, hydrolase activity, membrane fraction, membrane organization and biogenesis, mitochondrion, other, peptidase activity, protein catabolic process, protein modification process, transport, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,5,2.4,no,,,,, P110,47,D11,P110_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR070C,FMP16,,"Putative protein of unknown function; proposed to be involved in responding to conditions of stress; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,38,12.4,no,,,,, P110,48,D12,P110_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR072C,IPT1,KTI6;SYR4,"Inositolphosphotransferase, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), the most abundant sphingolipid;, can mutate to resistance to the antifungals syringomycin E and DmAMP1 and to K. lactis zymocin",cellular lipid metabolic process,transferase activity,membrane fraction,"lipid metabolic process, membrane fraction, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,30,11.3,no,,,,, P110,49,E1,P110_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR073W,SNF11,,Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p,chromosome organization,transcription regulator activity,nucleus,"nucleus, organelle organization and biogenesis, transcription regulator activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,54,16,no,,,,, P110,50,E2,P110_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR075W,PPH3,,Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p,"response to chemical stimulus, protein modification process","phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, other, phosphoprotein phosphatase activity, protein modification process, response to chemical stimulus",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,24,8.7,no,,,,, P110,51,E3,P110_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR076W,RAD55,,Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p,"response to stress, meiosis, cell cycle, DNA metabolic process","protein binding, hydrolase activity",nucleus,"DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, protein binding, response to stress",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,343,42,12.2,no,,,,, P110,52,E4,P110_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR078C,SHU2,,"Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu1p, Psy3p, and Csm2p","response to stress, DNA metabolic process",molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function, response to stress",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,16,6.1,no,,,,, P110,53,E5,P110_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR079W,PET100,,"Chaperone that specifically facilitates the assembly of cytochrome c oxidase, integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme","mitochondrion organization, generation of precursor metabolites and energy, protein complex biogenesis, cellular respiration",protein binding,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","Golgi apparatus, cellular respiration, cytoplasm, endomembrane system, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, protein binding",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,22,7.4,no,,,,, P110,54,E6,P110_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR080W,VPS41,VPL20;VAM2;SVL2;FET2;CVT8,Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport,"vacuole organization, transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular membrane organization","lipid binding, enzyme regulator activity","vacuole, membrane, cytoplasm","cytoplasm, enzyme regulator activity, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein modification process, transport, vacuole",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,12,5.5,no,,,,, P110,55,E7,P110_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR083W,RRP8,,"Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; also involved in telomere maintenance; mutation is synthetically lethal with a gar1 mutation","ribosome biogenesis, RNA metabolic process",transferase activity,"nucleus, nucleolus","RNA metabolic process, nucleolus, organelle organization and biogenesis, ribosome biogenesis, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,12,6.7,no,,,,, P110,56,E8,P110_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR084C,TVP23,,Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,"transport, vesicle-mediated transport",molecular_function,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, membrane, molecular_function, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,24,11.3,no,,,,, P110,57,E9,P110_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR085C,AFR1,,Protein required for pheromone-induced projection (shmoo) formation; regulates septin architecture during mating; has an RVXF motif that mediates targeting of Glc7p to mating projections; interacts with Cdc12p,"signaling process, conjugation, cellular component morphogenesis, response to chemical stimulus",signal transducer activity,other,"anatomical structure morphogenesis, conjugation, other, response to chemical stimulus, signal transducer activity, signal transduction",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,54,24.7,no,,,,, P110,58,E10,P110_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR089W,,,Protein of unknown function; deletion confers resistance to Nickel,cellular membrane organization,molecular_function,membrane,"membrane, membrane organization and biogenesis, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,17,8.9,no,,,,, P110,59,E11,P110_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR090C,,,Putative protein of unknown function,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,54,17.2,no,,,,, P110,60,E12,P110_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR092W,UBC13,,Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus,"response to stress, cellular homeostasis, DNA metabolic process, protein modification process, protein complex biogenesis",ligase activity,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, ligase activity, nucleus, other, protein modification process, response to stress",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,30,13.2,no,,,,, P110,61,F1,P110_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR093W,DNF2,,"Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase","transport, vesicle-mediated transport, cellular membrane organization","hydrolase activity, transporter activity","membrane fraction, membrane, plasma membrane","anatomical structure morphogenesis, hydrolase activity, membrane fraction, membrane organization and biogenesis, plasma membrane, transport, transporter activity, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,20,10.6,no,,,,, P110,62,F2,P110_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR094W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,28,13.7,no,,,,, P110,63,F3,P110_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR095C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,15,7,no,,,,, P110,64,F4,P110_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR096W,GIS1,,JmjC domain-containing histone demethylase; transcription factor involved in expression of genes during nutrient limitation and in negative regulation of DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis,"transcription, protein modification process, sporulation resulting in formation of a cellular spore, cellular lipid metabolic process, chromosome organization, cellular component morphogenesis, RNA metabolic process","transcription regulator activity, oxidoreductase activity, DNA binding","nucleus, mitochondrion, cytoplasm","DNA binding, cell wall organization and biogenesis, lipid metabolic process, mitochondrion, nucleus, organelle organization and biogenesis, oxidoreductase activity, protein modification process, sporulation, transcription regulator activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,19,9,no,,,,, P110,65,F5,P110_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR097C,MSH6,PMS3,"Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p","response to stress, meiosis, cell cycle, DNA metabolic process","DNA binding, hydrolase activity",nucleus,"DNA binding, DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, other, response to stress",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,18,9.1,no,,,,, P110,66,F6,P110_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR098C,GRX3,,Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage,"response to stress, cellular homeostasis, response to chemical stimulus",oxidoreductase activity,"nucleus, cytoplasm","cellular homeostasis, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,16,5,no,,,,, P110,67,F7,P110_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR099W,BMH2,SCD3,"14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling","signaling process, generation of precursor metabolites and energy, protein modification process, response to stress, cellular carbohydrate metabolic process, sporulation resulting in formation of a cellular spore, pseudohyphal growth, cell cycle, DNA metabolic process",DNA binding,"nucleus, membrane fraction","DNA binding, carbohydrate metabolic process, cell cycle, cell wall organization and biogenesis, generation of precursor metabolites and energy, nucleus, protein binding, pseudohyphal growth, response to stress, signal transduction, sporulation",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,34,12.3,no,,,,, P110,68,F8,P110_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR100W,TVP15,,Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p,"transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,15,8.3,no,,,,, P110,69,F9,P110_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR101C,ARX1,,Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex,ribosome biogenesis,molecular_function,"nucleus, ribosome, cytoplasm","cytoplasm, molecular_function, nucleus, organelle organization and biogenesis, ribosome, ribosome biogenesis",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,4,1.9,no,,,,, P110,70,F10,P110_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR102C,,,Dubious open reading frame; homozygous diploid deletion strain exhibits high budding index,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,36,11.6,no,,,,, P110,71,F11,P110_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR104C,SPO71,,"Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,cell wall,"cell wall, cell wall organization and biogenesis, molecular_function, sporulation",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,14,6.4,no,,,,, P110,72,F12,P110_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR105C,TMS1,,"Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance",biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,22,10.2,no,,,,, P110,73,G1,P110_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR107C,TMN2,,Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments,"pseudohyphal growth, cellular homeostasis",molecular_function,"membrane, vacuole, cytoplasm","membrane fraction, molecular_function, other, pseudohyphal growth",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,38,11.7,no,,,,, P110,74,G2,P110_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR108W,GSG1,MUM1;TRS85,"Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication","transport, vesicle organization, peroxisome organization, response to stress, meiosis, vesicle-mediated transport, cell cycle, cellular membrane organization",molecular_function,"Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, meiosis, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, other, transport, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,7,3.3,no,,,,, P110,75,G3,P110_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR109C,,,Putative kinase,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,24,12.1,no,,,,, P110,76,G4,P110_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR110W,FOB1,HRM1,"Nucleolar protein that binds the rDNA replication fork barrier (RFB) site; required for replication fork blocking, recombinational hotspot activity, condensin recruitment to RFB and rDNA repeat segregation; related to retroviral integrases","transcription, chromosome segregation, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process",DNA binding,"nucleus, nucleolus","DNA binding, DNA metabolic process, RNA metabolic process, nucleolus, organelle organization and biogenesis, other, transcription",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,24,8.1,no,,,,, P110,77,G5,P110_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR111C,ALT2,,Putative alanine transaminase (glutamic pyruvic transaminase),biological_process,transferase activity,"nucleus, cytoplasm","biological_process, cytoplasm, nucleus, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,27,12.7,no,,,,, P110,78,G6,P110_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR112W,IRC2,,"Dubious open reading frame, unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR111C; null mutant displays increased levels of spontaneous Rad52p foci",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,39,20.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P110,79,G7,P110_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR116C,MRPL1,,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation, generation of precursor metabolites and energy, cellular respiration",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, ribosome, structural molecule activity, translation",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,47,22.1,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P110,80,G8,P110_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR117C,TMA64,RBF64,Protein of unknown function that associates with ribosomes; has a putative RNA binding domain,biological_process,RNA binding,"ribosome, cytoplasm","RNA binding, biological_process, ribosome",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,8,3,no,,,,, P110,81,G9,P110_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR119W,VBA4,,Protein of unknown function with proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene,biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,46,15.1,no,,,,, P110,82,G10,P110_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR120C,TRM1,,"tRNA methyltransferase; two forms of the protein are made by alternative translation starts; localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments",RNA metabolic process,transferase activity,"nucleus, membrane, endomembrane system, mitochondrion, cytoplasm","RNA metabolic process, endomembrane system, membrane, mitochondrion, nucleus, ribosome biogenesis, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,10,5.7,no,,,,, P110,83,G11,P110_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR121W,DPB4,,Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing,"transcription, DNA metabolic process, RNA metabolic process","transferase activity, DNA binding, nucleotidyltransferase activity","nucleus, chromosome","DNA metabolic process, RNA metabolic process, chromosome, nucleotidyltransferase activity, nucleus, organelle organization and biogenesis, transcription, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,26,10.2,no,,,,, P110,84,G12,P110_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR122W,KIN1,,Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p,"transport, vesicle-mediated transport, protein modification process","transferase activity, protein kinase activity","membrane, plasma membrane","membrane, plasma membrane, protein kinase activity, protein modification process, transferase activity, transport, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,66,20.5,no,,,,, P110,85,H1,P110_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR123C,INO2,SCS1;DIE1,"Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion","cellular lipid metabolic process, transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, lipid metabolic process, nucleus, transcription, transcription regulator activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,144,14,9.7,no,,,,, P110,86,H2,P110_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR124W,,,Putative protein of unknown function; non-essential gene; expression is strongly induced by alpha factor,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,24,7.1,no,,,,, P110,87,H3,P110_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P110,88,H4,P110_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR125C,ECM18,,"Protein of unknown function, similar to Rlp24p",fungal-type cell wall organization,molecular_function,"mitochondrion, cytoplasm","cell wall organization and biogenesis, mitochondrion, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,33,19.4,no,,,,, P110,89,H5,P110_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR126W,SWF1,PSL10,"Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion","vacuole organization, transport, protein modification process, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cellular membrane organization",transferase activity,"cell cortex, cytoskeleton, endomembrane system, membrane, cytoplasm","cell wall organization and biogenesis, endomembrane system, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein modification process, sporulation, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,20,7.9,no,,,,, P110,90,H6,P110_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR128W,MTC5,,Protein of unknown function; mtc5 is synthetically sick with cdc13-1,biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,2,0.7,no,,,,, P110,91,H7,P110_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR129C,SAC6,ABP67,"Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton","transport, cell budding, cytoskeleton organization, cytokinesis, response to stress, vesicle-mediated transport, cell cycle, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, response to stress, transport, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,34,10.4,no,,,,, P110,92,H8,P110_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR130C,FIN1,,Spindle pole body-related intermediate filament protein; forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells; localization cell-cycle dependent; involved in Glc7p localization and regulation,"signaling process, cytoskeleton organization, chromosome segregation, chromosome organization, cell cycle","structural molecule activity, protein binding","nucleus, cytoskeleton, microtubule organizing center, chromosome, cytoplasm","cell cycle, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, nucleus, organelle organization and biogenesis, protein binding, structural molecule activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,34,15.6,no,,,,, P110,93,H9,P110_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR131C,,,"F-box protein, substrate-specific adaptor subunit that recruits substrates to a core ubiquitination complex","protein modification process, cellular protein catabolic process",ligase activity,other,"ligase activity, other, protein catabolic process, protein modification process",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,26,8.4,no,,,,, P110,94,H10,P110_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR132C,,,Putative protein of unknown function,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,22,10.8,no,,,,, P110,95,H11,P110_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR133C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,15,8.7,no,,,,, P110,96,H12,P110_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR134C,,,,,,,,,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,7,3.5,no,,,,, P111,1,A1,P111_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR135C,YCF1,,"Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR","transport, response to chemical stimulus","transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cytoplasm, hydrolase activity, membrane, response to chemical stimulus, transport, transporter activity, vacuole",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,6,3.4,no,,,,, P111,2,A2,P111_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR136C,VPS61,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 4% of ORF overlaps the verified gene RGP1; deletion causes a vacuolar protein sorting defect",transport,molecular_function,cellular_component,"cellular_component, molecular_function, transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,5,2.2,no,,,,, P111,3,A3,P111_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR137W,RGP1,,Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p,"transport, vesicle-mediated transport",enzyme regulator activity,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, enzyme regulator activity, membrane, other, transport, vesicle-mediated transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,9,5.2,no,,,,, P111,4,A4,P111_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER055C,HIS1,,"ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control","cellular amino acid and derivative metabolic process, heterocycle metabolic process",transferase activity,other,"amino acid and derivative metabolic process, other, transferase activity",,,05_3,,,"consortium notes: FAILED QC- grow -Lys, n/g -Met, n/g Aux, no mate A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,,180,10,5.6,no,,,,, P111,5,A5,P111_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR139C,RUB1,,"Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)",protein modification process,other,cytoplasm,"cytoplasm, other, protein modification process",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,18,5.6,no,,,,, P111,6,A6,P111_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR140W,MTQ2,,S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; subunit of complex with Trm112p that methylates translation release factor Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; similar to E.coli PrmC,"translation, protein modification process",transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, protein modification process, transferase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,25,14.2,no,,,,, P111,7,A7,P111_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR142C,PEX7,PEB1;PAS7,Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP),"transport, peroxisome organization, protein complex biogenesis",other,"peroxisome, cytoplasm","cytoplasm, organelle organization and biogenesis, other, peroxisome, transport",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,4,1.8,no,,,,, P111,8,A8,P111_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR143C,SAN1,,"Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins","response to stress, response to chemical stimulus, protein modification process, cellular protein catabolic process",ligase activity,"nucleus, cytoplasm","ligase activity, nucleus, protein catabolic process, protein modification process, response to chemical stimulus, response to stress",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,9,4.9,no,,,,, P111,9,A9,P111_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR144C,MKC7,YPS2,"GPI-anchored aspartyl protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; shares functions with Yap3p and Kex2p",fungal-type cell wall organization,"peptidase activity, hydrolase activity",cell wall,"cell wall, hydrolase activity, other, peptidase activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,11,5.4,no,,,,, P111,10,A10,P111_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR146C,SWI5,,Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase,"transcription, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","RNA metabolic process, cell cycle, cytoplasm, nucleus, transcription, transcription regulator activity",,,04_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,377,38,10.1,no,,,,, P111,11,A11,P111_A11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P111,12,A12,P111_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR338C,,,"Putative protein of unknown function, member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily",transport,transporter activity,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,7,3.8,no,,,,, P111,13,B1,P111_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR340W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,18,5.4,no,,,,, P111,14,B2,P111_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR344C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,3,1.6,no,,,,, P111,15,B3,P111_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR345C,HXT3,,"Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions",transport,transporter activity,"membrane, membrane fraction, plasma membrane","membrane fraction, plasma membrane, transport, transporter activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,8,3.3,no,,,,, P111,16,B4,P111_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR346C,SVF1,SGI1,"Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis","response to stress, response to chemical stimulus",molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, response to chemical stimulus, response to stress",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,8,3.6,no,,,,, P111,17,B5,P111_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR348C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck; potential Cdc28p substrate,biological_process,molecular_function,"cellular bud, site of polarized growth","biological_process, cellular bud, molecular_function, site of polarized growth",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,18,7.4,no,,,,, P111,18,B6,P111_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR349C,YPS7,,"Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; located in the cytoplasm and endoplasmic reticulum",fungal-type cell wall organization,"peptidase activity, hydrolase activity","endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endoplasmic reticulum, hydrolase activity, peptidase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,4,1.6,no,,,,, P111,19,B7,P111_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR351W,SBE2,,Protein involved in the transport of cell wall components from the Golgi to the cell surface; required for bud growth,fungal-type cell wall organization,molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, cell wall organization and biogenesis, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,12,4.8,no,,,,, P111,20,B8,P111_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR352W,,,Putative protein of unknown function,biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,11,5.1,no,,,,, P111,21,B9,P111_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR354W,TRP4,,"Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, nucleus, transferase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,4,2.8,no,,,,, P111,22,B10,P111_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR357C,,BLC1,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,12,5.9,no,,,,, P111,23,B11,P111_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR358W,GGA1,,"Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi","transport, vesicle-mediated transport, cellular protein catabolic process",protein binding,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, protein binding, protein catabolic process, transport, vesicle-mediated transport",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,3,1.7,no,,,,, P111,24,B12,P111_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR359C,EAF1,VID21,"Component of the NuA4 histone acetyltransferase complex; acts as a platform for assembly of NuA4 subunits into the native complex; required for initiation of pre-meiotic DNA replication, likely due to its requirement for expression of IME1","response to stress, chromosome organization, DNA metabolic process, protein complex biogenesis",molecular_function,nucleus,"DNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, response to stress",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,4,1.7,no,,,,, P111,25,C1,P111_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR360W,OPI7,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene VID21/YDR359C.",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,4,1.2,no,,,,, P111,26,C2,P111_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR363W,ESC2,,Protein involved in silencing; may recruit or stabilize Sir proteins; role in Rad51-dependent homologous recombination repair and intra S-phase DNA damage checkpoint; member of the RENi (Rad60-Esc2-Nip45) family of SUMO-like domain proteins,"signaling process, transcription, response to stress, cell cycle, DNA metabolic process, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, transcription",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,64,26.9,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P111,27,C3,P111_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR364C,CDC40,SLU4;SLT15;PRP17,"Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats","cell cycle, RNA metabolic process",other,nucleus,"RNA metabolic process, cell cycle, nucleus, other",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,212,4,1.9,no,,,,, P111,28,C4,P111_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR368W,YPR1,,"NADPH-dependent aldo-keto reductase, reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases","response to stress, cellular carbohydrate metabolic process, response to chemical stimulus",oxidoreductase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,16,6.3,no,,,,, P111,29,C5,P111_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR369C,XRS2,,"Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling","response to stress, meiosis, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle, DNA metabolic process","DNA binding, protein binding",nucleus,"DNA binding, DNA metabolic process, cell cycle, meiosis, nucleus, organelle organization and biogenesis, protein binding, response to stress, sporulation",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,19,9.2,no,,,,, P111,30,C6,P111_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR370C,,,Putative protein of unknown function,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,5,2.4,no,,,,, P111,31,C7,P111_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR371W,CTS2,,Protein similar to Ashbya gossypii sporulation-specific chitinase,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,12,5.9,no,,,,, P111,32,C8,P111_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR372C,VPS74,MNN3;API1,Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; binding to PtdIns4P required for Golgi targeting and function; tetramer formation required for function,"transport, response to chemical stimulus, response to stress, vesicle-mediated transport","lipid binding, protein binding","nucleus, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, membrane, nucleus, other, protein binding, response to chemical stimulus, response to stress, signal transduction, transport, vesicle-mediated transport",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,3,1.3,no,,,,, P111,33,C9,P111_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR374C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P111,34,C10,P111_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR378C,LSM6,,"Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA","ribosome biogenesis, RNA metabolic process",RNA binding,"nucleus, nucleolus, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, nucleolus, nucleus, other",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,241,24,10,no,,,,, P111,35,C11,P111_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR379W,RGA2,,"GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p","cell budding, signaling process, cytoskeleton organization, response to chemical stimulus, conjugation, pseudohyphal growth",enzyme regulator activity,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, conjugation, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, other, pseudohyphal growth, response to chemical stimulus, signal transduction, site of polarized growth",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,14,7.4,no,,,,, P111,36,C12,P111_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR380W,ARO10,,"Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",lyase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, lyase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,3,1.3,no,,,,, P111,37,D1,P111_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR382W,RPP2B,YP2beta;P2B;L45;YPA1;RPL45,"Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,1,0.5,no,,,,, P111,38,D2,P111_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR383C,NKP1,,"Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)",biological_process,molecular_function,chromosome,"biological_process, chromosome, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,30,10.2,no,,,,, P111,39,D3,P111_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR384C,ATO3,,"Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, other, plasma membrane, transport, transporter activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,10,3.1,no,,,,, P111,40,D4,P111_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR385W,EFT2,,"Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin",translation,RNA binding,"ribosome, cytoplasm","ribosome, translation, translation regulator activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,28,10.1,no,,,,, P111,41,D5,P111_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR386W,MUS81,SLX3,"Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in DNA repair, replication fork stability, and joint molecule formation/resolution during meiotic recombination; helix-hairpin-helix protein","response to stress, meiosis, cell cycle, DNA metabolic process, chromosome segregation",hydrolase activity,nucleus,"DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, other, response to stress",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,265,64,24.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P111,42,D6,P111_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR387C,,,"Putative transporter, member of the sugar porter family; YDR387C is not an essential gene",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,22,10.8,no,,,,, P111,43,D7,P111_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR388W,RVS167,,"Actin-associated protein, interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin","transport, vesicle-mediated transport, cellular membrane organization","lipid binding, protein binding","cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cytokinesis, cytoplasm, cytoskeleton, membrane organization and biogenesis, protein binding, response to stress, transport, vesicle-mediated transport",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,11,4.7,no,,,,, P111,44,D8,P111_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR389W,SAC7,,"GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate","signaling process, cytoskeleton organization, cell cycle",enzyme regulator activity,other,"cell cycle, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, other, signal transduction",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,12,5.7,no,,,,, P111,45,D9,P111_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR391C,,,"Putative protein of unknown function, possibly involved in zinc homeostasis; Bdf1p-dependent transcription induced by salt stress; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,7,3.6,no,,,,, P111,46,D10,P111_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR392W,SPT3,,"Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters","transcription, protein modification process, sporulation resulting in formation of a cellular spore, conjugation, chromosome organization, pseudohyphal growth, RNA metabolic process","transcription regulator activity, protein binding",nucleus,"RNA metabolic process, conjugation, nucleus, organelle organization and biogenesis, other, protein binding, protein modification process, pseudohyphal growth, sporulation, transcription, transcription regulator activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,7,3.7,no,,,,, P111,47,D11,P111_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR393W,SHE9,MDM33,"Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex","mitochondrion organization, cellular membrane organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,10,5.1,no,,,,, P111,48,D12,P111_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR395W,SXM1,KAP108,"Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1",transport,transporter activity,"nucleus, cytoplasm","nucleus, protein binding, transport, transporter activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,5,2.5,no,,,,, P111,49,E1,P111_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR399W,HPT1,HGPRTase;HPRT;BRA6,"Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome",heterocycle metabolic process,transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, other, transferase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,22,11.3,no,,,,, P111,50,E2,P111_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR400W,URH1,,"Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways","cofactor metabolic process, vitamin metabolic process, heterocycle metabolic process, cellular protein catabolic process",hydrolase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cofactor metabolic process, cytoplasm, heterocycle metabolic process, hydrolase activity, nucleus, other, protein catabolic process, vitamin metabolic process",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,14,5.3,no,,,,, P111,51,E3,P111_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR401W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,22,11.2,no,,,,, P111,52,E4,P111_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR402C,DIT2,CYP56,"N-formyltyrosine oxidase, sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",oxidoreductase activity,cellular_component,"cell wall organization and biogenesis, cellular_component, oxidoreductase activity, sporulation",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,18,6.4,no,,,,, P111,53,E5,P111_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR403W,DIT1,,"Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",other,cellular_component,"cell wall organization and biogenesis, cellular_component, other, sporulation",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,22,7.4,no,,,,, P111,54,E6,P111_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR405W,MRP20,YmL41;MRPL41,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,10,5.6,no,,,,, P111,55,E7,P111_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR406W,PDR15,,"Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element","transport, response to chemical stimulus","transporter activity, hydrolase activity",membrane,"hydrolase activity, membrane, response to chemical stimulus, transport, transporter activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,22,6.9,no,,,,, P111,56,E8,P111_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR408C,ADE8,,"Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway","heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, nucleus, other, transferase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,30,9.4,no,,,,, P111,57,E9,P111_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR409W,SIZ1,ULL1,SUMO/Smt3 ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring,"protein modification process, chromosome segregation",ligase activity,"nucleus, cell cortex, cytoskeleton, chromosome, cytoplasm","cell cortex, chromosome, cytoplasm, cytoskeleton, ligase activity, nucleus, other, protein modification process",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,8,4.3,no,,,,, P111,58,E10,P111_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR410C,STE14,,"Farnesyl cysteine-carboxyl methyltransferase, mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane",protein modification process,transferase activity,"nucleus, membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein modification process, transferase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,11,5.8,no,,,,, P111,59,E11,P111_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR411C,DFM1,,ER localized derlin-like family member involved in ER stress and homeostasis; not involved in ERAD or substrate retrotranslocation; interacts with CDC48; contains four transmembrane domains and two SHP boxes,"response to stress, response to chemical stimulus",molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, response to chemical stimulus, response to stress, signal transduction",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,24,7.6,no,,,,, P111,60,E12,P111_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR414C,ERD1,LDB2,"Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)","cellular carbohydrate metabolic process, protein modification process",molecular_function,membrane,"membrane, molecular_function, other, protein modification process",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,225,18,8,no,,,,, P111,61,F1,P111_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR415C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,7,3.6,no,,,,, P111,62,F2,P111_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR418W,RPL12B,YL23;L15B;L12B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins","translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,26,11.6,no,,,,, P111,63,F3,P111_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR419W,RAD30,DBH1,"DNA polymerase eta, involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; mutations in human pol eta are responsible for XPV","response to stress, DNA metabolic process","transferase activity, nucleotidyltransferase activity",chromosome,"DNA metabolic process, chromosome, nucleotidyltransferase activity, response to stress, transferase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,22,8,no,,,,, P111,64,F4,P111_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR420W,HKR1,,"Mucin family member that functions as an osmosensor in the Sho1p-mediated HOG pathway with Msb2p; proposed to be a negative regulator of filamentous growth; mutant displays defects in beta-1,3 glucan synthesis and bud site selection","fungal-type cell wall organization, cytokinesis, response to stress, cellular carbohydrate metabolic process, cell cycle",signal transducer activity,"membrane, site of polarized growth, plasma membrane","anatomical structure morphogenesis, carbohydrate metabolic process, cell wall organization and biogenesis, cytokinesis, plasma membrane, response to stress, signal transducer activity, signal transduction",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,3,1.3,no,,,,, P111,65,F5,P111_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR421W,ARO80,,Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids,"transcription, cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, amino acid and derivative metabolic process, aromatic compound metabolic process, nucleus, transcription, transcription regulator activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,28,13.6,no,,,,, P111,66,F6,P111_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR422C,SIP1,,"Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions","signaling process, protein modification process, protein complex biogenesis","transferase activity, protein kinase activity","vacuole, cytoplasm","cytoplasm, other, protein kinase activity, protein modification process, signal transduction, transferase activity, vacuole",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,266,41,15.4,no,,,,, P111,67,F7,P111_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR423C,CAD1,YAP2,"AP-1-like basic leucine zipper (bZIP) transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA","transcription, response to chemical stimulus, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,11,5,no,,,,, P111,68,F8,P111_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR425W,SNX41,,"Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; interacts with Snx4p","transport, vesicle-mediated transport",lipid binding,cytoplasm,"cytoplasm, lipid binding, transport, vesicle-mediated transport",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,9,5.1,no,,,,, P111,69,F9,P111_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR426C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SNX41",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,18,6.5,no,,,,, P111,70,F10,P111_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR428C,BNA7,,"Formylkynurenine formamidase, involved in the de novo biosynthesis of NAD from tryptophan via kynurenine","cofactor metabolic process, vitamin metabolic process",hydrolase activity,cellular_component,"cellular_component, cofactor metabolic process, hydrolase activity, vitamin metabolic process",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,12,4.7,no,,,,, P111,71,F11,P111_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR430C,CYM1,MOP112,"Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology",cellular protein catabolic process,"peptidase activity, hydrolase activity","mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrial envelope, mitochondrion, other, peptidase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,6,2.4,no,,,,, P111,72,F12,P111_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR431W,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,324,12,3.7,no,,,,, P111,73,G1,P111_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR432W,NPL3,NAB1;NOP3;MTS1;MTR13,"RNA-binding protein that promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; required for pre-mRNA splicing; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm","transport, translation, transcription, pseudohyphal growth, RNA metabolic process","transcription regulator activity, RNA binding","nucleus, cytoplasm","RNA binding, cytoplasm, nucleus, pseudohyphal growth, transport",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,19,8,no,,,,, P111,74,G2,P111_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR433W,,KRE22,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",response to stress,molecular_function,cellular_component,"cellular_component, molecular_function, response to stress",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,331,10,3,no,,,,, P111,75,G3,P111_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR435C,PPM1,,"Carboxyl methyltransferase, methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits","protein modification process, protein complex biogenesis",transferase activity,cellular_component,"cellular_component, protein modification process, transferase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,24,11.3,no,,,,, P111,76,G4,P111_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR436W,PPZ2,,"Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance",cellular homeostasis,"phosphoprotein phosphatase activity, hydrolase activity",cellular_component,"cellular homeostasis, cellular_component, hydrolase activity, phosphoprotein phosphatase activity",,,04_7,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,20,8.7,no,,,,, P111,77,G5,P111_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL001C,IRC22,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,40,15.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P111,78,G6,P111_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL003W,GIM4,PFD2,Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it,protein complex biogenesis,protein binding,cytoplasm,"cytoplasm, other, protein binding",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,20,7.6,no,,,,, P111,79,G7,P111_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL005C,VAB2,VAB31,"Protein with a potential role in vacuolar function, as suggested by its ability to bind Vac8p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern",biological_process,protein binding,cytoplasm,"biological_process, cytoplasm, protein binding",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,14,4.9,no,,,,, P111,80,G8,P111_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL006W,YEA6,NDT2,"Putative mitochondrial NAD+ transporter, member of the mitochondrial carrier subfamily (see also YIA6); has putative human ortholog",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,290,20,6.9,no,,,,, P111,81,G9,P111_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL007W,,TOS9,Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1),biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,14,5,no,,,,, P111,82,G10,P111_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL008W,,,Hypothetical protein predicted to be involved in metabolism,biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, other",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,162,28,17.3,no,,,,, P111,83,G11,P111_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL009C,GCN4,AAS101;ARG9;AAS3,Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels,"transcription, protein complex biogenesis, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, amino acid and derivative metabolic process, nucleus, response to chemical stimulus, response to stress, signal transduction, transcription, transcription regulator activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,296,66,22.3,no,,,,, P111,84,G12,P111_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL010W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,22,10.4,no,,,,, P111,85,H1,P111_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL013W,VAC8,YEB3,"Phosphorylated and palmitoylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions","vacuole organization, transport, vesicle organization, response to stress, cellular membrane organization",protein binding,"vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vacuole",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,237,9,3.8,no,,,,, P111,86,H2,P111_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL014C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,26,8.3,no,,,,, P111,87,H3,P111_H3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P111,88,H4,P111_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL015W,EDC3,LSM16;DCP3,"Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically affecting the function of the decapping enzyme Dcp1p; localizes to cytoplasmic mRNA processing bodies",RNA metabolic process,molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, other",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,19,10.2,no,,,,, P111,89,H5,P111_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL016C,NPP2,,Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp1p and Pho5p; activity and expression enhanced during conditions of phosphate starvation,other,hydrolase activity,cellular_component,"cellular_component, hydrolase activity, other",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,18,5.6,no,,,,, P111,90,H6,P111_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL017C-A,PMP2,,Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; nearly identical to PMP1,transport,molecular_function,membrane,"membrane, molecular_function, transport",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,22,7.3,no,,,,, P111,91,H7,P111_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL017W,GTT3,,"Protein of unknown function with a possible role in glutathione metabolism, as suggested by computational analysis of large-scale protein-protein interaction data; GFP-fusion protein localizes to the nuclear periphery",biological_process,molecular_function,cellular_component,"cellular_component, cofactor metabolic process, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,36,12.9,no,,,,, P111,92,H8,P111_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL018W,EAF5,,"Esa1p-associated factor, non-essential subunit of the NuA4 acetyltransferase complex","response to stress, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, molecular_function, nucleus, response to stress",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,20,7.9,no,,,,, P111,93,H9,P111_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL020C,,,Hypothetical protein with low sequence identity to Pdc1p,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,48,15.3,no,,,,, P111,94,H10,P111_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL023C,,,Putative protein of unknown function; expression is increased greatly during sporulation; YEL023C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,24,12.1,no,,,,, P111,95,H11,P111_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL024W,RIP1,,"Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,18,6.5,no,,,,, P111,96,H12,P111_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL025C,,SRI1,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,18,9.5,no,,,,, P112,1,A1,P112_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL027W,CUP5,VMA3;GEF2;CLS7,Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis,"vacuole organization, transport, vesicle-mediated transport, cellular homeostasis, cellular membrane organization",transporter activity,"vacuole, membrane, cytoplasm","cellular homeostasis, cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, transport, transporter activity, vacuole, vesicle-mediated transport",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,241,24,10,no,,,,, P112,2,A2,P112_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL028W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,12,5.7,no,,,,, P112,3,A3,P112_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL030W,ECM10,SSC3,"Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner; overexpression induces extensive mitochondrial DNA aggregations","transport, protein folding, mitochondrion organization",molecular_function,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, molecular_function, organelle organization and biogenesis, protein folding, transport",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,8,4.6,no,,,,, P112,4,A4,P112_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL031W,SPF1,PER9;PIO1;COD1,"P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1","transport, cellular homeostasis","hydrolase activity, transporter activity","endomembrane system, mitochondrion, membrane, endoplasmic reticulum, Golgi apparatus, cytoplasm","cellular homeostasis, cytoplasm, endomembrane system, endoplasmic reticulum, hydrolase activity, membrane, mitochondrion, protein modification process, transporter activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,2,0.7,no,,,,, P112,5,A5,P112_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL033W,MTC7,,"Predicted metabolic role based on network analysis derived from ChIP experiments, a large-scale deletion study and localization of transcription factor binding sites; null mutant is sensitive to temperature oscillation in a cdc13-1 mutant",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, other",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,24,7.9,no,,,,, P112,6,A6,P112_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER016W,BIM1,EB1;YEB1,Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally,"transport, signaling process, cytoskeleton organization, chromosome segregation, chromosome organization, cell cycle",structural molecule activity,"cytoskeleton, microtubule organizing center, chromosome, cytoplasm","cell cycle, chromosome, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, organelle organization and biogenesis, structural molecule activity, transport",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,20,8.3,no,,,,, P112,7,A7,P112_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL037C,RAD23,,"Protein with ubiquitin-like N terminus, subunit of Nuclear Excision Repair Factor 2 (NEF2) with Rad4p that recognizes and binds damaged DNA; enhances protein deglycosylation activity of Png1p; homolog of human HR23A and HR23B","protein modification process, response to stress, chromosome organization, DNA metabolic process, cellular protein catabolic process","hydrolase activity, DNA binding, protein binding","nucleus, mitochondrion, cytoplasm","DNA binding, DNA metabolic process, mitochondrion, nucleus, organelle organization and biogenesis, other, protein binding, protein catabolic process, response to stress",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,233,9,3.9,no,,,,, P112,8,A8,P112_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL038W,UTR4,,"Protein with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatases, involved in methionine salvage; found in both the cytoplasm and nucleus",cellular amino acid and derivative metabolic process,hydrolase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, molecular_function, nucleus",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,199,19,9.5,no,,,,, P112,9,A9,P112_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL039C,CYC7,iso-2-cytochrome c,"Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration","generation of precursor metabolites and energy, cellular respiration",other,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, generation of precursor metabolites and energy, mitochondrial envelope, mitochondrion, other",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,6,2.9,no,,,,, P112,10,A10,P112_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL040W,UTR2,CRH2,Chitin transglycosylase that functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar to and functionally redundant with Crh1; glycosylphosphatidylinositol (GPI)-anchored protein localized to bud neck,fungal-type cell wall organization,transferase activity,"cell cortex, membrane fraction, cytoskeleton, cell wall, cellular bud, site of polarized growth, cytoplasm","cell cortex, cell wall, cell wall organization and biogenesis, cellular bud, cytoplasm, cytoskeleton, membrane fraction, molecular_function, site of polarized growth",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,23,13.1,no,,,,, P112,11,A11,P112_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL041W,YEF1,,ATP-NADH kinase; phosphorylates both NAD and NADH; homooctameric structure consisting of 60-kDa subunits; sequence similarity to Utr1p and Pos5p; overexpression complements certain pos5 phenotypes,"cofactor metabolic process, vitamin metabolic process",transferase activity,cellular_component,"cellular_component, cofactor metabolic process, transferase activity, vitamin metabolic process",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,204,25,12.3,no,,,,, P112,12,A12,P112_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P112,13,B1,P112_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL042W,GDA1,,"Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate","cellular carbohydrate metabolic process, protein modification process",hydrolase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, hydrolase activity, protein modification process",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,189,30,15.9,no,,,,, P112,14,B2,P112_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL043W,,,"Predicted cytoskeleton protein involved in intracellular signalling based on quantitative analysis of protein-protein interaction maps; may interact with ribosomes, based on co-purification studies; contains fibronectin type III domain fold",biological_process,molecular_function,"ribosome, endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function, ribosome",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,4,1.6,no,,,,, P112,15,B3,P112_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER028C,MIG3,,"Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes","response to stress, transcription, protein complex biogenesis, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, nucleus, response to stress, transcription, transcription regulator activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,4,1.4,no,,,,, P112,16,B4,P112_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL045C,,,"Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; deletion gives MMS sensitivity, growth defect under alkaline conditions, less than optimal growth upon citric acid stress",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,382,4,1,no,,,,, P112,17,B5,P112_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL046C,GLY1,,"Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis",cellular amino acid and derivative metabolic process,lyase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, lyase activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,4,1.9,no,,,,, P112,18,B6,P112_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL047C,,FRDS1,"Soluble fumarate reductase, required with isoenzyme Osm1p for anaerobic growth; may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies","response to stress, response to chemical stimulus",oxidoreductase activity,"membrane fraction, ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity, ribosome",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,304,30,9.9,no,,,,, P112,19,B7,P112_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL048C,TCA17,,Protein that interacts with subunits of the TRAPP complex and may play a role its assembly or stability; mutation is synthetically lethal with gcs1 deletion; Sedlin_N family member; human Sedlin mutations cause the skeletal disorder SEDT,biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,8,3,no,,,,, P112,20,B8,P112_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL049W,PAU2,,"Member of the seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,5,2.6,no,,,,, P112,21,B9,P112_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL050C,RML2,,"Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L2 ribosomal protein; fat21 mutant allele causes inability to utilize oleate and may interfere with activity of the Adr1p transcription factor","cellular lipid metabolic process, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, lipid metabolic process, mitochondrion, ribosome, structural molecule activity, translation",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,10,5.4,no,,,,, P112,22,B10,P112_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL051W,VMA8,,"Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,316,28,8.9,no,,,,, P112,23,B11,P112_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL052W,AFG1,,Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain,"transport, peroxisome organization, response to chemical stimulus, response to stress, cellular protein catabolic process",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, protein catabolic process, response to chemical stimulus, response to stress",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,332,44,13.3,no,,,,, P112,24,B12,P112_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL053C,MAK10,NAA35,"Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus; expression is glucose-repressible",protein modification process,transferase activity,cytoplasm,"cytoplasm, protein modification process, transferase activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,0,0,no,,,,, P112,25,C1,P112_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL054C,RPL12A,YL23;L15A;L12A,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins","translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,192,11,5.7,no,,,,, P112,26,C2,P112_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL056W,HAT2,,"Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing","chromosome organization, transcription, protein modification process, RNA metabolic process","transferase activity, protein binding","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription, transferase activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,152,6,3.9,no,,,,, P112,27,C3,P112_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL057C,,,Protein of unknown function involved in telomere maintenance; target of UME6 regulation,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,10,3,no,,,,, P112,28,C4,P112_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL059W,HHY1,ENV6,Dubious open reading frame unlikely to encode a functional protein; mutant is hypersensitive to hygromycin B indicative of defects in vacuolar trafficking,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,8,3.8,no,,,,, P112,29,C5,P112_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL060C,PRB1,CVT1,"Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation; activity inhibited by Pbi2p","response to stress, sporulation resulting in formation of a cellular spore, cellular protein catabolic process","peptidase activity, hydrolase activity","vacuole, cytoplasm","cytoplasm, hydrolase activity, peptidase activity, protein catabolic process, response to stress, sporulation, vacuole",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,4,1.8,no,,,,, P112,30,C6,P112_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL061C,CIN8,SDS15;KSL2,Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation,"cytoskeleton organization, chromosome segregation, chromosome organization, cell cycle","motor activity, hydrolase activity","nucleus, cytoskeleton, chromosome, mitochondrion, cytoplasm","cell cycle, chromosome, cytoskeleton, cytoskeleton organization and biogenesis, mitochondrion, motor activity, nucleus, organelle organization and biogenesis",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,4,1.9,no,,,,, P112,31,C7,P112_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL062W,NPR2,,Component of an evolutionarily conserved Npr2/3 complex that mediates downregulation of TORC1 activity in response to amino acid limitation; homolog of human NPRL2; target of Grr1p (E3 ligase); required for growth on urea and proline,"transport, response to stress, signaling process, response to chemical stimulus",molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus, transport",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,255,25,9.8,no,,,,, P112,32,C8,P112_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL063C,CAN1,,"Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","membrane, mitochondrion, plasma membrane, transport, transporter activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,11,6.1,no,,,,, P112,33,C9,P112_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL064C,AVT2,,"Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters",transport,transporter activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, transport, transporter activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,2,1.1,no,,,,, P112,34,C10,P112_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL065W,SIT1,ARN3,"Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; transcription is induced during iron deprivation and diauxic shift; potentially phosphorylated by Cdc28p","transport, cellular homeostasis",transporter activity,"cytoplasmic membrane-bounded vesicle, cytoplasm","cellular homeostasis, cytoplasm, cytoplasmic membrane-bounded vesicle, transport, transporter activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,6,2.6,no,,,,, P112,35,C11,P112_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL066W,HPA3,,"D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro",cellular amino acid and derivative metabolic process,transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, organelle organization and biogenesis, protein modification process, transferase activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,3,1.6,no,,,,, P112,36,C12,P112_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL067C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,194,39,20.1,no,,,,, P112,37,D1,P112_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL068C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,300,24,8,no,,,,, P112,38,D2,P112_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL071W,DLD3,,"D-lactate dehydrogenase, part of the retrograde regulon which consists of genes whose expression is stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source, located in the cytoplasm",other,oxidoreductase activity,cytoplasm,"cytoplasm, other, oxidoreductase activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,0,0,no,,,,, P112,39,D3,P112_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL072W,RMD6,,Protein required for sporulation,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,3,1.2,no,,,,, P112,40,D4,P112_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER001W,MNN1,,"Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, protein modification process, transferase activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,3,1.7,no,,,,, P112,41,D5,P112_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER002W,NOP16,,"Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis",ribosome biogenesis,molecular_function,"nucleus, nucleolus","cytoplasm, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,328,48,14.6,no,,,,, P112,42,D6,P112_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER004W,FMP52,,"Protein of unknown function, localized to the mitochondrial outer membrane; induced by treatment with 8-methoxypsoralen and UVA irradiation",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endoplasmic reticulum, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,8,3.5,no,,,,, P112,43,D7,P112_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER005W,YND1,YEJ5,"Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p","protein modification process, cellular carbohydrate metabolic process",hydrolase activity,"membrane fraction, cytoplasmic membrane-bounded vesicle, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, hydrolase activity, membrane, membrane fraction, protein modification process",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,8,2.7,no,,,,, P112,44,D8,P112_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER007C-A,TMA20,RBF20,Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma22p; null mutant exhibits translation defects; has homology to human oncogene MCT-1,ribosome biogenesis,RNA binding,"ribosome, cytoplasm","RNA binding, cytoplasm, ribosome, ribosome biogenesis",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,4,2.1,no,,,,, P112,45,D9,P112_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER007W,PAC2,,"Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl",protein folding,protein binding,cellular_component,"cellular_component, protein binding, protein folding",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,6,2,no,,,,, P112,46,D10,P112_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER010C,,,"Protein of unknown function, forms a ring-shaped homotrimer; has similarity to members of the prokaryotic rraA family; possibly involved in a phosphotransfer reaction",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,300,26,8.7,no,,,,, P112,47,D11,P112_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER011W,TIR1,SRP1,Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking,response to stress,structural molecule activity,cell wall,"cell wall, response to stress, structural molecule activity",,,05_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,254,5,2,no,,,,, P112,48,D12,P112_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER019W,ISC1,,"Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance","response to stress, cellular lipid metabolic process",hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, endoplasmic reticulum, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, endoplasmic reticulum, hydrolase activity, lipid metabolic process, membrane, mitochondrial envelope, mitochondrion, response to stress",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,305,16,5.2,no,,,,, P112,49,E1,P112_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER019C-A,SBH2,SEB2,"Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p",transport,enzyme regulator activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, enzyme regulator activity, membrane, transport",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,267,2,0.7,no,,,,, P112,50,E2,P112_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER020W,GPA2,SSP101,"Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery","signaling process, heterocycle metabolic process, response to chemical stimulus, sporulation resulting in formation of a cellular spore, pseudohyphal growth",hydrolase activity,"membrane fraction, mitochondrion, membrane, cytoplasm, plasma membrane","hydrolase activity, mitochondrion, other, plasma membrane, pseudohyphal growth, response to chemical stimulus, signal transduction, sporulation",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,2,0.6,no,,,,, P112,51,E3,P112_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER024W,YAT2,,"Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane","cellular amino acid and derivative metabolic process, vitamin metabolic process",transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, other, transferase activity, vitamin metabolic process",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,2,0.8,no,,,,, P112,52,E4,P112_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER030W,CHZ1,,Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif,chromosome organization,protein binding,nucleus,"nucleus, organelle organization and biogenesis, protein binding",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,314,6,1.9,no,,,,, P112,53,E5,P112_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER033C,ZRG8,,"Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency",fungal-type cell wall organization,molecular_function,"cellular bud, site of polarized growth, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,187,5,2.7,no,,,,, P112,54,E6,P112_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER034W,,,Putative protein of unknown function; non-essential gene; expression induced upon calcium shortage,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,294,4,1.4,no,,,,, P112,55,E7,P112_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER035W,EDC2,,"RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p; has a role in translation during heat stress","response to stress, translation, RNA metabolic process",RNA binding,"nucleus, nucleolus, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, nucleus",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,9,4.7,no,,,,, P112,56,E8,P112_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER038W-A,,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 99% of ORF overlaps the verified gene HVG1; protein product detected in mitochondria",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,183,4,2.2,no,,,,, P112,57,E9,P112_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER040W,GLN3,,"Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source","transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding, protein binding","nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, nucleus, other, transcription, transcription regulator activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,19,9.4,no,,,,, P112,58,E10,P112_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER041W,YEN1,,Holliday junction resolvase; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1 and has similarity to S. cerevisiae endonuclease Rth1p,"response to stress, DNA metabolic process",hydrolase activity,"nucleus, cytoplasm","biological_process, hydrolase activity, nucleus",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,277,0,0,no,,,,, P112,59,E11,P112_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER042W,MXR1,MSRA,"Methionine-S-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR2; involved in the regulation of lifespan","response to stress, response to chemical stimulus",oxidoreductase activity,"nucleus, cytoplasm","cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,199,5,2.5,no,,,,, P112,60,E12,P112_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER044C-A,MEI4,,Meiosis-specific protein involved in double-strand break formation during meiotic recombination; required for chromosome synapsis and production of viable spores,"meiosis, cell cycle",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleus, sporulation",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,284,24,8.5,no,,,,, P112,61,F1,P112_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER045C,ACA1,,"Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources","transcription, protein complex biogenesis, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,182,8,4.4,no,,,,, P112,62,F2,P112_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER046W-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,1,0.5,no,,,,, P112,63,F3,P112_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER047C,SAP1,,"Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system",biological_process,hydrolase activity,cytoplasm,"biological_process, cytoplasm, hydrolase activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,180,6,3.3,no,,,,, P112,64,F4,P112_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER048C,CAJ1,,"Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly",protein folding,protein binding,nucleus,"biological_process, nucleus, other",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,1,0.5,no,,,,, P112,65,F5,P112_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER049W,TPA1,,"Poly(rA)-binding protein involved in translation termination efficiency, mRNA poly(A) tail length and mRNA stability; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; similar to prolyl 4-hydroxylases; binds Fe(III) and 2-oxoglutarate","translation, RNA metabolic process",RNA binding,nucleus,"RNA metabolic process, molecular_function, nucleus, ribosome biogenesis, translation",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,198,14,7.1,no,,,,, P112,66,F6,P112_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER051W,JHD1,KDM2;JHDM1,"JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe","chromosome organization, protein modification process","protein binding, oxidoreductase activity",cellular_component,"cellular_component, organelle organization and biogenesis, oxidoreductase activity, protein binding, protein modification process",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,282,14,5,no,,,,, P112,67,F7,P112_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER053C,PIC2,,"Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Mir1p but less abundant than Mir1p under normal conditions; expression is induced at high temperature",transport,transporter activity,"mitochondrion, cytoplasm","mitochondrion, transport, transporter activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,6,2,no,,,,, P112,68,F8,P112_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER054C,GIP2,,"Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p","cellular carbohydrate metabolic process, generation of precursor metabolites and energy, protein modification process",enzyme regulator activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, enzyme regulator activity, generation of precursor metabolites and energy, protein modification process",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,8,4.8,no,,,,, P112,69,F9,P112_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER056C,FCY2,BRA7,"Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,4,1.9,no,,,,, P112,70,F10,P112_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER056C-A,RPL34A,L34A,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,6,3.1,no,,,,, P112,71,F11,P112_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER058W,PET117,,Protein required for assembly of cytochrome c oxidase,"mitochondrion organization, protein complex biogenesis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,3,1.3,no,,,,, P112,72,F12,P112_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER059W,PCL6,,Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding,"cellular carbohydrate metabolic process, generation of precursor metabolites and energy",enzyme regulator activity,other,"carbohydrate metabolic process, enzyme regulator activity, generation of precursor metabolites and energy, other",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,1,0.6,no,,,,, P112,73,G1,P112_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER060W,FCY21,,"Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function",transport,transporter activity,membrane,"biological_process, membrane, transporter activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,191,3,1.6,no,,,,, P112,74,G2,P112_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER062C,HOR2,GPP2,"One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition","response to stress, cellular carbohydrate metabolic process, generation of precursor metabolites and energy",hydrolase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, nucleus, response to stress",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,8,4.2,no,,,,, P112,75,G3,P112_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER065C,ICL1,,"Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose",cellular carbohydrate metabolic process,lyase activity,cellular_component,"carbohydrate metabolic process, cellular_component, lyase activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,218,13,6,no,,,,, P112,76,G4,P112_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER067W,RGI1,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YER067W is not an essential gene; protein abundance is increased upon intracellular iron depletion,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,193,19,9.8,no,,,,, P112,77,G5,P112_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER067C-A,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YER067W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,320,6,1.9,no,,,,, P112,78,G6,P112_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER044C,ERG28,BUD18,"Endoplasmic reticulum membrane protein, may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p",other,protein binding,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, protein binding",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,260,24,9.2,no,,,,, P112,79,G7,P112_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER068C-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,0,0,no,,,,, P112,80,G8,P112_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER069W,"ARG5,6",,"Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p","transcription, cellular amino acid and derivative metabolic process","transferase activity, oxidoreductase activity","mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, oxidoreductase activity, transcription, transferase activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,232,11,4.7,no,,,,, P112,81,G9,P112_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER071C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,biological_process,molecular_function,"site of polarized growth, cytoplasm","biological_process, cytoplasm, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,275,21,7.6,no,,,,, P112,82,G10,P112_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER072W,VTC1,PHM4;NRF1,"Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion","vacuole organization, transport, cellular membrane organization",molecular_function,"vacuole, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vacuole",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,205,15,7.3,no,,,,, P112,83,G11,P112_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER073W,ALD5,,"Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed",other,oxidoreductase activity,"mitochondrion, cytoplasm","mitochondrion, other, oxidoreductase activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,12,3.7,no,,,,, P112,84,G12,P112_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER074W,RPS24A,S24A;RPS24EA,Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,7,4.1,no,,,,, P112,85,H1,P112_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER075C,PTP3,,Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm,"signaling process, response to chemical stimulus, protein modification process, response to stress, conjugation","hydrolase activity, phosphoprotein phosphatase activity","nucleus, cytoplasm","conjugation, cytoplasm, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process, response to chemical stimulus, response to stress, signal transduction",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,2,1.2,no,,,,, P112,86,H2,P112_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER080W,AIM9,FMP29,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,13,5.7,no,,,,, P112,87,H3,P112_H3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P112,88,H4,P112_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER081W,SER3,,"3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser33p",cellular amino acid and derivative metabolic process,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, oxidoreductase activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,253,25,9.9,no,,,,, P112,89,H5,P112_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER083C,GET2,RMD7;HUR2,Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for meiotic nuclear division,"transport, fungal-type cell wall organization, vesicle-mediated transport, cellular membrane organization",protein binding,"membrane, endoplasmic reticulum, cytoplasm","cell wall organization and biogenesis, cytoplasm, endoplasmic reticulum, molecular_function, transport, vesicle-mediated transport",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,268,28,10.4,no,,,,, P112,90,H6,P112_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER084W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,3,1.8,no,,,,, P112,91,H7,P112_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER085C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,275,46,16.7,no,,,,, P112,92,H8,P112_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER086W,ILV1,ISO1,"Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation",cellular amino acid and derivative metabolic process,lyase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, lyase activity, mitochondrion",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,218,10,4.6,no,,,,, P112,93,H9,P112_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER087W,AIM10,,Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays elevated frequency of mitochondrial genome loss,biological_process,ligase activity,"mitochondrion, cytoplasm","biological_process, ligase activity, mitochondrion",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,175,13,7.4,no,,,,, P112,94,H10,P112_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER087C-B,SBH1,YER087C-A;SEB1,Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involved in protein translocation into the endoplasmic reticulum; interacts with the exocyst complex and also with Rtn1p; homologous to Sbh2p,transport,"transporter activity, enzyme regulator activity","membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, enzyme regulator activity, membrane, protein binding, transport, transporter activity",,,05_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,324,28,8.6,no,,,,, P112,95,H11,P112_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR123C,PPT1,,Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; computational analyses suggest roles in phosphate metabolism and rRNA processing,protein modification process,"phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process, ribosome biogenesis",,,07_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,172,1,0.6,no,,,,, P112,96,H12,P112_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR124W,ASN2,,"Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway",cellular amino acid and derivative metabolic process,ligase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, ligase activity",,,07_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,336,0,0,no,,,,, P115,1,A1,P115_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR184W,SSP1,SPO3,Protein involved in the control of meiotic nuclear division and coordination of meiosis with spore formation; transcription is induced midway through meiosis,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis, protein complex biogenesis",molecular_function,membrane,"cell wall organization and biogenesis, membrane, molecular_function, other, sporulation",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,6,2.1,no,,,,, P115,2,A2,P115_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR189W,PTH1,PTH,"One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for respiratory growth on rich medium, but required for respiratory growth on minimal medium","mitochondrion organization, translation",hydrolase activity,"mitochondrion, cytoplasm","hydrolase activity, mitochondrion, translation",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,23,9.5,no,,,,, P115,3,A3,P115_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR195W,NVJ1,VAB36,"Nuclear envelope protein, anchored to the nuclear inner membrane, that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN)",cellular membrane organization,protein binding,"nucleus, endomembrane system","endomembrane system, membrane organization and biogenesis, nucleus, protein binding",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,18,6.9,no,,,,, P115,4,A4,P115_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR198C,AIM18,FMP22,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,14,4.5,no,,,,, P115,5,A5,P115_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR199C,AIM46,FMP34,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,7,3.1,no,,,,, P115,6,A6,P115_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR200W,RPN10,SUN1;MCB1,Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein,cellular protein catabolic process,"structural molecule activity, protein binding",other,"hydrolase activity, other, peptidase activity, protein catabolic process",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,32,9.8,no,,,,, P115,7,A7,P115_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR202W,,,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole, while HA-tagged protein is found in the soluble fraction, suggesting cytoplasmic localization",biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, other, vacuole",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,4,2.1,no,,,,, P115,8,A8,P115_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR203C,RPS4B,rp5;YS6;S7B;S4B,Protein component of the small (40S) ribosomal subunit; identical to Rps4Ap and has similarity to rat S4 ribosomal protein,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,4,1.7,no,,,,, P115,9,A9,P115_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR204W,MNL1,HTM1,"alpha-1,2-specific exomannosidase of the endoplasmic reticulum that generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation",cellular protein catabolic process,hydrolase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, other, protein catabolic process",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,6,3.1,no,,,,, P115,10,A10,P115_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR206W,SKN7,POS9;BRY1,"Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation","response to stress, transcription, response to chemical stimulus","DNA binding, signal transducer activity",nucleus,"DNA binding, nucleus, other, response to chemical stimulus, response to stress, signal transducer activity, transcription, transcription regulator activity",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,12,4.3,no,,,,, P115,11,A11,P115_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR207C,SET5,,"Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,8,4.2,no,,,,, P115,12,A12,P115_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR209W,CRG1,,Putative S-adenosylmethionine-dependent methyltransferase; mediates cantharidin resistance,biological_process,transferase activity,cellular_component,"biological_process, cellular_component, transferase activity",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,16,5.7,no,,,,, P115,13,B1,P115_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR210C,,,Putative protein of unknown function; non-essential gene; highly expressed under anaeorbic conditions; sequence similarity to aldose 1-epimerases such as GAL10,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,08_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,241,0,0,no,,,,, P115,14,B2,P115_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL001W,RER1,,"Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER","transport, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, other, transport, vesicle-mediated transport",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,16,7.3,no,,,,, P115,15,B3,P115_B3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P115,16,B4,P115_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL002C,,,Putative protein of unknown function; YCL002C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,2,1.1,no,,,,, P115,17,B5,P115_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL004W,PGS1,YCL003W;PEL1,"Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis",cellular lipid metabolic process,transferase activity,"mitochondrion, cytoplasm","lipid metabolic process, mitochondrion, transferase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,310,10,3.2,no,,,,, P115,18,B6,P115_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL005W,LDB16,,Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,140,12,8.6,no,,,,, P115,19,B7,P115_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL007C,,CWH36,"Dubious ORF unlikely to encode a protein; overlaps verified ORF YCL005W-A; mutations in YCL007C were thought to confer sensitivity to calcofluor white, but this phenotype was later shown to be due to the defect in YCL005W-A",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,24,12.5,no,,,,, P115,20,B8,P115_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL008C,STP22,VPL15;VPS23,"Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype","transport, vesicle-mediated transport, cellular protein catabolic process",protein binding,"membrane, plasma membrane, cytoplasm","cytoplasm, membrane, protein binding, protein catabolic process, transport",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,8,3.3,no,,,,, P115,21,B9,P115_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL009C,ILV6,,"Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria",cellular amino acid and derivative metabolic process,"transferase activity, enzyme regulator activity","mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, enzyme regulator activity, mitochondrion, transferase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,10,5.3,no,,,,, P115,22,B10,P115_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL011C,GBP2,RLF6,"Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro","transport, chromosome organization, DNA metabolic process","RNA binding, DNA binding","nucleus, cytoplasm","DNA binding, RNA binding, nucleus, organelle organization and biogenesis, transport",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,158,10,6.3,no,,,,, P115,23,B11,P115_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL014W,BUD3,YCL012W,Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding,"cell budding, cytokinesis, cell cycle",molecular_function,"cellular bud, cell cortex, site of polarized growth, cytoskeleton, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, molecular_function, site of polarized growth",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,140,6,4.3,no,,,,, P115,24,B12,P115_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL013W,,,,,,,,,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P115,25,C1,P115_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL014W,BUD3,YCL012W,Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding,"cell budding, cytokinesis, cell cycle",molecular_function,"cellular bud, cell cortex, site of polarized growth, cytoskeleton, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, molecular_function, site of polarized growth",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,6,2.2,no,,,,, P115,26,C2,P115_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL016C,DCC1,,"Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance","response to stress, chromosome organization, cell cycle, chromosome segregation",molecular_function,chromosome,"cell cycle, chromosome, molecular_function, organelle organization and biogenesis, response to stress",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,10,5.4,no,,,,, P115,27,C3,P115_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL024W,KCC4,,"Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p","cell budding, cytoskeleton organization, cytokinesis, protein modification process, protein complex biogenesis, cell cycle","transferase activity, protein kinase activity","cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cycle, cellular bud, cytokinesis, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein kinase activity, protein modification process, site of polarized growth",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,24,7.7,no,,,,, P115,28,C4,P115_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL025C,AGP1,YCC5,"Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,18,7,no,,,,, P115,29,C5,P115_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL026C-A,FRM2,YCLX08C,"Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis; expression induced in cells treated with the mycotoxin patulin; has similarity to bacterial nitroreductases",cellular lipid metabolic process,oxidoreductase activity,"nucleus, cytoplasm","cytoplasm, lipid metabolic process, nucleus, oxidoreductase activity, response to chemical stimulus",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,30,9.2,no,,,,, P115,30,C6,P115_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL027W,FUS1,,"Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate","conjugation, cellular component morphogenesis, response to chemical stimulus",molecular_function,"membrane, site of polarized growth, plasma membrane","anatomical structure morphogenesis, conjugation, molecular_function, plasma membrane, response to chemical stimulus, site of polarized growth",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,24,7.5,no,,,,, P115,31,C7,P115_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL028W,RNQ1,[PIN(+)],"[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,8,3.1,no,,,,, P115,32,C8,P115_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL029C,BIK1,PAC14;ARM5,"Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170","transport, cytoskeleton organization, conjugation, cell cycle, nucleus organization",protein binding,"nucleus, cell cortex, cytoskeleton, microtubule organizing center, chromosome, site of polarized growth, cytoplasm","cell cortex, cell cycle, chromosome, conjugation, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, protein binding",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,6,2,no,,,,, P115,33,C9,P115_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL033C,MXR2,MSRB,"Methionine-R-sulfoxide reductase, involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan","response to stress, response to chemical stimulus",oxidoreductase activity,cellular_component,"cellular_component, oxidoreductase activity, response to chemical stimulus, response to stress",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,148,4,2.7,no,,,,, P115,34,C10,P115_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL034W,LSB5,,"Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; may mediate disassembly of the Pan1 complex from the endocytic coat","transport, cytoskeleton organization, vesicle-mediated transport, cellular membrane organization",molecular_function,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoskeleton organization and biogenesis, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vesicle-mediated transport",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,10,3.4,no,,,,, P115,35,C11,P115_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL036W,GFD2,YCD6,"Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,10,3.3,no,,,,, P115,36,C12,P115_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL037C,SRO9,,"Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif",translation,RNA binding,other,"RNA binding, other, ribosome biogenesis, translation",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,16,6.6,no,,,,, P115,37,D1,P115_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL039W,GID7,MOH2,"Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions","cellular carbohydrate metabolic process, cellular protein catabolic process",molecular_function,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, molecular_function, nucleus, other, protein catabolic process",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,16,5.3,no,,,,, P115,38,D2,P115_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL040W,GLK1,HOR3,"Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources","transport, cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,"membrane fraction, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity, transport",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,8,2.5,no,,,,, P115,39,D3,P115_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL042W,,,Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,11,5.9,no,,,,, P115,40,D4,P115_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL044C,MGR1,,"Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr3p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA",cellular protein catabolic process,protein binding,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,200,16,8,no,,,,, P115,41,D5,P115_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL045C,EMC1,,Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; interacts with Gal80p,protein folding,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,2,0.9,no,,,,, P115,42,D6,P115_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL046W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YCL045C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,8,3,no,,,,, P115,43,D7,P115_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL047C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,14,4.2,no,,,,, P115,44,D8,P115_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL048W,SPS22,,"Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall","fungal-type cell wall organization, sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,"membrane, plasma membrane","cell wall organization and biogenesis, molecular_function, plasma membrane, sporulation",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,2,0.6,no,,,,, P115,45,D9,P115_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL049C,,,Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene;,biological_process,molecular_function,membrane fraction,"biological_process, membrane fraction, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,16,6.3,no,,,,, P115,46,D10,P115_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL050C,APA1,DTP1,"Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p",other,hydrolase activity,"nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, other",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,5,2.5,no,,,,, P115,47,D11,P115_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL051W,LRE1,,Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes,"response to stress, fungal-type cell wall organization","transcription regulator activity, enzyme regulator activity",cell wall,"cell wall, cell wall organization and biogenesis, enzyme regulator activity, response to stress, transcription regulator activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,12,5.8,no,,,,, P115,48,D12,P115_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL055W,KAR4,,"Transcription factor required for gene regulation in response to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone","transcription, response to chemical stimulus, meiosis, conjugation, cell cycle, RNA metabolic process, nucleus organization",other,"nucleus, cytoplasm","DNA binding, RNA metabolic process, cell cycle, conjugation, cytoplasm, meiosis, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, response to chemical stimulus, transcription, transcription regulator activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,17,8.1,no,,,,, P115,49,E1,P115_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL056C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; null mutant displays decreased thermotolerance,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,14,5,no,,,,, P115,50,E2,P115_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL057W,PRD1,,"Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins",other,"peptidase activity, hydrolase activity","mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrial envelope, mitochondrion, other, peptidase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,12,4.3,no,,,,, P115,51,E3,P115_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL061C,MRC1,YCL060C,"S-phase checkpoint protein required for DNA replication; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; protects uncapped telomeres","signaling process, transcription, chromosome segregation, response to stress, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, RNA metabolic process, cell cycle, chromosome, molecular_function, nucleus, organelle organization and biogenesis, transcription",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,6,2.9,no,,,,, P115,52,E4,P115_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL061C,MRC1,YCL060C,"S-phase checkpoint protein required for DNA replication; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; protects uncapped telomeres","signaling process, transcription, chromosome segregation, response to stress, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, RNA metabolic process, cell cycle, chromosome, molecular_function, nucleus, organelle organization and biogenesis, transcription",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,0,0,no,,,,, P115,53,E5,P115_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,,,,,,,,,,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P115,54,E6,P115_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL063W,VAC17,YCL062W,Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p,vacuole organization,protein binding,"membrane, vacuole, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, protein binding, vacuole",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,0,0,no,,,,, P115,55,E7,P115_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL064C,CHA1,,"Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine",cellular amino acid and derivative metabolic process,lyase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, lyase activity, mitochondrion",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,12,4.4,no,,,,, P115,56,E8,P115_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL069W,VBA3,,Permease of basic amino acids in the vacuolar membrane,transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,10,5.4,no,,,,, P115,57,E9,P115_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR001W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YCR001W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,6,3.2,no,,,,, P115,58,E10,P115_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR004C,YCP4,,"Protein of unknown function, has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,other,"membrane, membrane fraction, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, other",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,24,8.5,no,,,,, P115,59,E11,P115_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR005C,CIT2,,"Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors","cellular carbohydrate metabolic process, cellular amino acid and derivative metabolic process",transferase activity,"peroxisome, mitochondrion, cytoplasm","amino acid and derivative metabolic process, carbohydrate metabolic process, mitochondrion, other, peroxisome, transferase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,32,11.2,no,,,,, P115,60,E12,P115_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR006C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,8,4.5,no,,,,, P115,61,F1,P115_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR007C,,,"Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,10,3.9,no,,,,, P115,62,F2,P115_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR008W,SAT4,HAL4,Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p,"cell cycle, cellular homeostasis","transferase activity, protein kinase activity",cellular_component,"cell cycle, cellular homeostasis, cellular_component, protein kinase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,6,3.2,no,,,,, P115,63,F3,P115_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR009C,RVS161,SPE161;FUS7;END6,"Amphiphysin-like lipid raft protein; interacts with Rvs167p and regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress","transport, cytoskeleton organization, response to stress, vesicle-mediated transport, conjugation, cellular membrane organization","lipid binding, protein binding","cell cortex, cytoskeleton, membrane, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cytokinesis, cytoplasm, cytoskeleton, membrane, membrane organization and biogenesis, other, protein binding, response to stress, transport, vesicle-mediated transport",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,16,7.4,no,,,,, P115,64,F4,P115_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR010C,ADY2,ATO1,Acetate transporter required for normal sporulation; phosphorylated in mitochondria,transport,transporter activity,"membrane, membrane fraction, mitochondrion, plasma membrane, cytoplasm","mitochondrion, other, plasma membrane, transport, transporter activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,8,4.8,no,,,,, P115,65,F5,P115_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR011C,ADP1,,Putative ATP-dependent permease of the ABC transporter family of proteins,transport,"transporter activity, hydrolase activity","membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, hydrolase activity, membrane, transport, transporter activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,4,1.4,no,,,,, P115,66,F6,P115_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR014C,POL4,POLX,"DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta","response to stress, DNA metabolic process","transferase activity, nucleotidyltransferase activity",nucleus,"DNA metabolic process, nucleotidyltransferase activity, nucleus, response to stress, transferase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,20,7.6,no,,,,, P115,67,F7,P115_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR015C,,,Putative protein of unknown function; YCR015C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,20,7.6,no,,,,, P115,68,F8,P115_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR016W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus and nucleus; predicted to be involved in ribosome biogenesis,biological_process,molecular_function,"nucleus, nucleolus","molecular_function, nucleolus, nucleus, ribosome biogenesis",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,12,6.6,no,,,,, P115,69,F9,P115_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR017C,CWH43,,Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion,"fungal-type cell wall organization, protein modification process, cellular lipid metabolic process",molecular_function,"cellular bud, membrane, site of polarized growth, plasma membrane","cell wall organization and biogenesis, cellular bud, lipid metabolic process, membrane, molecular_function, plasma membrane, protein modification process, site of polarized growth",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,8,4.1,no,,,,, P115,70,F10,P115_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR019W,MAK32,,Protein necessary for structural stability of L-A double-stranded RNA-containing particles,other,molecular_function,cellular_component,"cellular_component, molecular_function, other",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,181,5,2.8,no,,,,, P115,71,F11,P115_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR020C,PET18,HIT2,"Protein of unknown function, has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin","vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",molecular_function,cytoplasm,"cytoplasm, molecular_function, organelle organization and biogenesis, vitamin metabolic process",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,26,9.8,no,,,,, P115,72,F12,P115_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR020C-A,MAK31,NAA38;SMX1;LSM9,Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family,protein modification process,transferase activity,cytoplasm,"cytoplasm, protein modification process, transferase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,0,0,no,,,,, P115,73,G1,P115_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR021C,HSP30,YRO1,"Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase","response to stress, heterocycle metabolic process",molecular_function,"membrane, membrane fraction, plasma membrane","molecular_function, other, plasma membrane, response to stress",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,154,22,14.3,no,,,,, P115,74,G2,P115_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR022C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YCR022C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,23,11.7,no,,,,, P115,75,G3,P115_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR023C,,,Vacuolar membrane protein of unknown function; member of the multidrug resistance family; YCR023C is not an essential gene,biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,14,5.4,no,,,,, P115,76,G4,P115_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR420W,URA4,,"Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate","heterocycle metabolic process, cellular aromatic compound metabolic process",hydrolase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, hydrolase activity, nucleus, other",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,4,1.4,no,,,,, P115,77,G5,P115_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR451W,LEU3,,"Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis","transcription, cellular amino acid and derivative metabolic process, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, amino acid and derivative metabolic process, nucleus, transcription, transcription regulator activity",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,4,2.3,no,,,,, P115,78,G6,P115_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR126C,,,Putative protein of unknown function with similarity to glutamine amidotransferase proteins; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein,cellular homeostasis,molecular_function,cytoplasm,"cellular homeostasis, cytoplasm, molecular_function",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,8,2.5,no,,,,, P115,79,G7,P115_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR128W,DCN1,,Scaffold-type E3 ligase required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation,protein modification process,"protein binding, ligase activity",cellular_component,"cellular_component, enzyme regulator activity, other, protein binding, protein modification process",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,4,1.5,no,,,,, P115,80,G8,P115_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR130C,ZRT2,,Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor,transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,0,0,no,,,,, P115,81,G9,P115_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR131C,ACE2,,"Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate","transcription, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","RNA metabolic process, cell cycle, cytoplasm, nucleus, transcription, transcription regulator activity",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,5,2.9,no,,,,, P115,82,G10,P115_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR133W,CKI1,,"Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway","cellular lipid metabolic process, cellular amino acid and derivative metabolic process",transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, lipid metabolic process, transferase activity",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,4,1.3,no,,,,, P115,83,G11,P115_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR134W,PDC5,,"Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism","cellular amino acid and derivative metabolic process, heterocycle metabolic process, generation of precursor metabolites and energy, cellular aromatic compound metabolic process, cellular carbohydrate metabolic process",lyase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, generation of precursor metabolites and energy, heterocycle metabolic process, lyase activity, nucleus, other",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,0,0,no,,,,, P115,84,G12,P115_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR135W,SLX4,,Endonuclease involved in processing DNA during recombination and repair; cleaves branched structures in a complex with Slx1p; involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing,"response to stress, DNA metabolic process",hydrolase activity,"nucleus, chromosome","DNA metabolic process, chromosome, hydrolase activity, nucleus, response to stress",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,16,5.3,no,,,,, P115,85,H1,P115_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR136C,TIS11,CTH2,mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis,"cellular homeostasis, RNA metabolic process",RNA binding,"nucleus, cytoplasm","RNA binding, RNA metabolic process, cellular homeostasis, cytoplasm, nucleus",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,4,2.5,no,,,,, P115,86,H2,P115_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR137W,,,Putative S-adenosylmethionine-dependent methyltransferase,biological_process,transferase activity,cellular_component,"biological_process, cellular_component, molecular_function",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,6,3.3,no,,,,, P115,87,H3,P115_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P115,88,H4,P115_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR138W,NHA1,,Na+/H+ antiporter involved in sodium and potassium efflux through the plasma membrane; required for alkali cation tolerance at acidic pH,"response to stress, cellular homeostasis",transporter activity,"membrane, plasma membrane","cellular homeostasis, plasma membrane, response to stress, transporter activity",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,18,7.8,no,,,,, P115,89,H5,P115_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR142W,PUT1,,"Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source","cellular amino acid and derivative metabolic process, heterocycle metabolic process",oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, oxidoreductase activity",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,8,3.8,no,,,,, P115,90,H6,P115_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR143W,,,Putative protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; YLR143W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,348,0,0,no,,,,, P115,91,H7,P115_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR149C,,,Putative protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutation results in a decrease in plasma membrane electron transport; YLR149C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,1,0.5,no,,,,, P115,92,H8,P115_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR150W,STM1,MPT4,Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with ribosomes; involved in TOR signaling; binds G4 quadruplex and purine motif triplex nucleic acid; helps maintain telomere structure,"signaling process, translation, response to stress, chromosome organization, DNA metabolic process",DNA binding,"ribosome, cytoplasm","DNA binding, cytoplasm, organelle organization and biogenesis, other, response to stress, ribosome, signal transduction, translation",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,9,5.1,no,,,,, P115,93,H9,P115_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR151C,PCD1,,"Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids",biological_process,hydrolase activity,"peroxisome, cytoplasm","biological_process, hydrolase activity, peroxisome",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,0,0,no,,,,, P115,94,H10,P115_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR152C,,,Putative protein of unknown function; YLR152C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,0,0,no,,,,, P115,95,H11,P115_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR154C,RNH203,Rnh2C,"Ribonuclease H2 subunit, required for RNase H2 activity; related to human AGS3 that causes Aicardi-Goutieres syndrome","DNA metabolic process, RNA metabolic process",hydrolase activity,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, hydrolase activity, nucleus, other",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,7,3.4,no,,,,, P115,96,H12,P115_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR164W,,,"Mitochondrial inner membrane of unknown function; similar to Tim18p and Sdh4p; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,12_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,2,0.6,no,,,,, P117,1,A1,P117_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL075C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; proposed to be involved in resistance to streptozotocin and camptothecin,response to chemical stimulus,molecular_function,cytoplasm,"cytoplasm, molecular_function, response to chemical stimulus",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,7,3.1,no,,,,, P117,2,A2,P117_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL076C,PSY1,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 69% of ORF overlaps the uncharacterized ORF YKL075C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,11,5.7,no,,,,, P117,3,A3,P117_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL077W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,279,24,8.6,no,,,,, P117,4,A4,P117_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL079W,SMY1,,"Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-terminal domain is related to the motor domain of kinesins","transport, vesicle-mediated transport","motor activity, hydrolase activity","cellular bud, site of polarized growth","cellular bud, motor activity, other, site of polarized growth, transport, vesicle-mediated transport",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,6,2.4,no,,,,, P117,5,A5,P117_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL080W,VMA5,VAT3;CSL5,"Subunit C of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,7,3.1,no,,,,, P117,6,A6,P117_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL081W,TEF4,EFC1,"Gamma subunit of translational elongation factor eEF1B, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the ribosomal complex",translation,RNA binding,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, translation, translation regulator activity",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,10,5.6,no,,,,, P117,7,A7,P117_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL084W,HOT13,,"Mitochondrial intermembrane space protein, first component of a pathway mediating assembly of small TIM (Translocase of the Inner Membrane) complexes which escort hydrophobic inner membrane proteins en route to the TIM22 complex","transport, mitochondrion organization",molecular_function,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, transport",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,289,2,0.7,no,,,,, P117,8,A8,P117_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL085W,MDH1,,"Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, oxidoreductase activity",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,2,0.9,no,,,,, P117,9,A9,P117_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL086W,SRX1,,"Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxin Tsa1p, which is formed upon exposure to oxidants; conserved in higher eukaryotes","response to stress, response to chemical stimulus",oxidoreductase activity,"nucleus, cytoplasm","cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,2,0.8,no,,,,, P117,10,A10,P117_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL090W,CUE2,,"Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination",biological_process,protein binding,cellular_component,"biological_process, cellular_component, protein binding",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,4,1.3,no,,,,, P117,11,A11,P117_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL091C,,SFH1,"Putative homolog of Sec14p, which is a phosphatidylinositol/phosphatidylcholine transfer protein involved in lipid metabolism; localizes to the nucleus",biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,2,1.1,no,,,,, P117,12,A12,P117_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL092C,BUD2,ERC25;CLA2,GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types,"cell budding, signaling process, cytokinesis, cell cycle",enzyme regulator activity,other,"anatomical structure morphogenesis, cell budding, cytokinesis, enzyme regulator activity, other, signal transduction",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,4,1.8,no,,,,, P117,13,B1,P117_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL093W,MBR1,,"Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants","generation of precursor metabolites and energy, cellular respiration",molecular_function,cellular_component,"cellular respiration, cellular_component, generation of precursor metabolites and energy, molecular_function",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,10,4.7,no,,,,, P117,14,B2,P117_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL094W,YJU3,,"Monoglyceride lipase (MGL), functional ortholog of mammalian MGL, localizes to lipid particles and membranes, also member of the eukaryotic serine hydrolase family",cellular lipid metabolic process,hydrolase activity,"membrane, membrane fraction, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion",,,11_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,4,1.9,no,,,,, P117,15,B3,P117_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL096W,CWP1,YJU1,"Cell wall mannoprotein that localizes specifically to birth scars of daughter cells, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance","fungal-type cell wall organization, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cellular membrane organization",structural molecule activity,"cell wall, membrane","cell wall, cell wall organization and biogenesis, structural molecule activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,0,0,no,,,,, P117,16,B4,P117_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL097C,,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,263,17,6.5,no,,,,, P117,17,B5,P117_B5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P117,18,B6,P117_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL098W,MTC2,,Protein of unknown function; mtc2 is synthetically sick with cdc13-1,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,18,5.5,no,,,,, P117,19,B7,P117_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL100C,,,Putative protein of unknown function with similarity to a human minor histocompatibility antigen and signal peptide peptidases; YKL100C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,1,0.5,no,,,,, P117,20,B8,P117_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL101W,HSL1,ELM2;NIK1,"Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p","signaling process, cytokinesis, protein modification process, cell cycle","transferase activity, protein kinase activity","cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell cortex, cell cycle, cellular bud, cytoplasm, cytoskeleton, protein kinase activity, protein modification process, site of polarized growth",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,2,1.1,no,,,,, P117,21,B9,P117_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL102C,,,Dubious open reading frame unlikely to encode a functional protein; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,4,1.5,no,,,,, P117,22,B10,P117_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL103C,LAP4,API;YSC1;APE1,Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway,cellular protein catabolic process,"peptidase activity, hydrolase activity","vacuole, cytoplasm","cytoplasm, hydrolase activity, peptidase activity, protein catabolic process, vacuole",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,246,14,5.7,no,,,,, P117,23,B11,P117_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL105C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,263,4,1.5,no,,,,, P117,24,B12,P117_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL106W,AAT1,,"Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis",cellular amino acid and derivative metabolic process,transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, transferase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,6,2.8,no,,,,, P117,25,C1,P117_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL107W,,,Putative protein of unknown function; proposed to be a palmitoylated membrane protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,10,5.2,no,,,,, P117,26,C2,P117_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL109W,HAP4,,"Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex",transcription,transcription regulator activity,nucleus,"carbohydrate metabolic process, nucleus, transcription, transcription regulator activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,4,1.8,no,,,,, P117,27,C3,P117_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL110C,KTI12,TOT4,"Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p","transcription, RNA metabolic process",other,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, other, transcription",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,4,2.2,no,,,,, P117,28,C4,P117_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL113C,RAD27,FEN1;RTH1;ERC11,"5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family","response to stress, DNA metabolic process, RNA metabolic process",hydrolase activity,"nucleus, mitochondrion, cytoplasm","DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, other, response to stress",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,44,16.1,no,,,,, P117,29,C5,P117_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL116C,PRR1,,"Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor","conjugation, transcription, response to chemical stimulus, RNA metabolic process","transferase activity, signal transducer activity, protein kinase activity",cytoplasm,"RNA metabolic process, conjugation, cytoplasm, protein kinase activity, response to chemical stimulus, signal transducer activity, transcription, transferase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,2,0.8,no,,,,, P117,30,C6,P117_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL117W,SBA1,,Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins and like p23 can regulate telomerase activity,"protein folding, chromosome organization, DNA metabolic process",protein binding,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, nucleus, organelle organization and biogenesis, other, protein binding, protein folding",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,8,4.3,no,,,,, P117,31,C7,P117_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL118W,,,"Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene VPH2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,8,4.3,no,,,,, P117,32,C8,P117_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL119C,VPH2,VMA12;CLS10,"Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)","cellular homeostasis, protein complex biogenesis",molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cellular homeostasis, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, other",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,14,5.3,no,,,,, P117,33,C9,P117_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL120W,OAC1,,"Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate; member of the mitochondrial carrier family",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,202,13,6.4,no,,,,, P117,34,C10,P117_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL121W,DGR2,,Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,2,0.8,no,,,,, P117,35,C11,P117_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL123W,,,"Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene SSH4",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,11,5.4,no,,,,, P117,36,C12,P117_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL124W,SSH4,MLF4,"Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the multivesicular body; identified as a high-copy suppressor of a SHR3 deletion, increasing steady-state levels of amino acid permeases","transport, vesicle-mediated transport, cellular protein catabolic process",molecular_function,"vacuole, cytoplasm","cytoplasm, molecular_function, protein catabolic process, transport, vacuole, vesicle-mediated transport",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,1,0.3,no,,,,, P117,37,D1,P117_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL126W,YPK1,SLI2,Serine/threonine protein kinase that phosphorylates and downregulates flippase activator Fpk1p; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK,"transport, protein modification process, protein complex biogenesis, cellular membrane organization","transferase activity, protein kinase activity","cellular bud, membrane, site of polarized growth, cytoplasm, plasma membrane","cellular bud, cytoplasm, lipid metabolic process, membrane organization and biogenesis, plasma membrane, protein kinase activity, protein modification process, site of polarized growth, transferase activity, transport, vesicle-mediated transport",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,6,2.8,no,,,,, P117,38,D2,P117_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL127W,PGM1,,"Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",isomerase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, isomerase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,6,3.5,no,,,,, P117,39,D3,P117_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL128C,PMU1,,"Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,225,2,0.9,no,,,,, P117,40,D4,P117_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL129C,MYO3,,"One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization","transport, fungal-type cell wall organization, cell budding, cytokinesis, response to stress, vesicle-mediated transport, cell cycle, cellular membrane organization","motor activity, hydrolase activity","cell cortex, cytoskeleton, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cell wall organization and biogenesis, cytokinesis, cytoplasm, cytoskeleton, membrane organization and biogenesis, motor activity, other, response to stress, transport, vesicle-mediated transport",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,5,2.8,no,,,,, P117,41,D5,P117_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL130C,SHE2,,RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud,DNA metabolic process,RNA binding,"cellular bud, site of polarized growth, cytoplasm","DNA metabolic process, RNA binding, cellular bud, cytoplasm, other, site of polarized growth",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,271,7,2.6,no,,,,, P117,42,D6,P117_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL131W,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,12,5.8,no,,,,, P117,43,D7,P117_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL132C,RMA1,,"Putative dihydrofolate synthetase; has similarity to Fol3p and to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,ligase activity,"mitochondrion, cytoplasm","biological_process, ligase activity, mitochondrion",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,3,1.5,no,,,,, P117,44,D8,P117_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL133C,,,"Putative protein of unknown function; has similarity to Mgr3p, but unlike MGR3, is not required for growth of cells lacking the mitochondrial genome (null mutation does not confer a petite-negative phenotype)",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,4,1.6,no,,,,, P117,45,D9,P117_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL136W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF APL2/YKL135C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,6,2.6,no,,,,, P117,46,D10,P117_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL137W,CMC1,,"Evolutionarily conserved copper-binding protein of the mitochondrial intermembrane space, may be involved in delivering copper from the matrix to the cytochrome c oxidase complex; contains a twin CX9C motif","mitochondrion organization, protein complex biogenesis",other,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,0,0,no,,,,, P117,47,D11,P117_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL140W,TGL1,YKL5,"Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes",cellular lipid metabolic process,hydrolase activity,"membrane, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, membrane",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,4,1.8,no,,,,, P117,48,D12,P117_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL142W,MRP8,YKL3,Protein of unknown function; undergoes sumoylation; transcription induced under cell wall stress; protein levels are reduced under anaerobic conditions; originally thought to be a mitochondrial ribosomal protein based on sequence analysis,biological_process,molecular_function,cytoplasm,"cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,10,4.4,no,,,,, P117,49,E1,P117_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL143W,LTV1,YKL2,"Component of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; required for ribosomal small subunit export from nucleus; required for growth at low temperature","transport, response to chemical stimulus, response to stress, ribosome biogenesis",molecular_function,"nucleus, membrane, cytoplasm","cytoplasm, membrane, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, response to chemical stimulus, response to stress, ribosome biogenesis, transport",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,10,4.4,no,,,,, P117,50,E2,P117_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL146W,AVT3,,"Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters",transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,10,3.6,no,,,,, P117,51,E3,P117_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL147C,,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene AVT3",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,200,7,3.5,no,,,,, P117,52,E4,P117_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL148C,SDH1,SDHA,"Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,24,7.5,no,,,,, P117,53,E5,P117_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL149C,DBR1,PRP26,"RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition","pseudohyphal growth, transposition, RNA metabolic process",hydrolase activity,nucleus,"RNA metabolic process, hydrolase activity, nucleus, pseudohyphal growth, transposition",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,0,0,no,,,,, P117,54,E6,P117_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL150W,MCR1,,"Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis","response to stress, response to chemical stimulus",oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, lipid metabolic process, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, response to chemical stimulus, response to stress",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,6,2.3,no,,,,, P117,55,E7,P117_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL151C,,,Putative protein of unknown function; YKL151C promoter contains STREs (stress response elements) and expression is induced by heat shock or methyl methanesulfonate; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,244,35,14.3,no,,,,, P117,56,E8,P117_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL155C,RSM22,,Mitochondrial ribosomal protein of the small subunit; also predicted to be an S-adenosylmethionine-dependent methyltransferase,"mitochondrion organization, translation","transferase activity, structural molecule activity","ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,6,2.9,no,,,,, P117,57,E9,P117_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL156W,RPS27A,rp61;YS20;S27A,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Bp and has similarity to rat S27 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,6,2.6,no,,,,, P117,58,E10,P117_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL157W,APE2,YKL158W;LAP1,Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W,other,"peptidase activity, hydrolase activity","extracellular region, mitochondrion, cytoplasm","extracellular region, hydrolase activity, mitochondrion, other, peptidase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,22,10.1,no,,,,, P117,59,E11,P117_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL157W,APE2,YKL158W;LAP1,Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W,other,"peptidase activity, hydrolase activity","extracellular region, mitochondrion, cytoplasm","extracellular region, hydrolase activity, mitochondrion, other, peptidase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,322,2,0.6,no,,,,, P117,60,E12,P117_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL159C,RCN1,,Protein involved in calcineurin regulation during calcium signaling; has similarity to H. sapiens DSCR1 which is found in the Down Syndrome candidate region,signaling process,"protein binding, enzyme regulator activity",cytoplasm,"enzyme regulator activity, other, signal transduction",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,307,10,3.3,no,,,,, P117,61,F1,P117_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL160W,ELF1,,Transcription elongation factor that contains a conserved zinc finger domain; implicated in the maintenance of proper chromatin structure in actively transcribed regions; deletion inhibits Brome mosaic virus (BMV) gene expression,"chromosome organization, transcription, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity, transposition",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,20,7.1,no,,,,, P117,62,F2,P117_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL161C,KDX1,MLP1,Protein kinase implicated in the Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p,biological_process,"transferase activity, protein kinase activity",cellular_component,"biological_process, cellular_component, protein kinase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,4,1.7,no,,,,, P117,63,F3,P117_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL162C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,3,1.4,no,,,,, P117,64,F4,P117_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL163W,PIR3,CCW8,"O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway",fungal-type cell wall organization,structural molecule activity,cell wall,"cell wall, cell wall organization and biogenesis, structural molecule activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,12,6.7,no,,,,, P117,65,F5,P117_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL164C,PIR1,CCW6,"O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle","transport, fungal-type cell wall organization",structural molecule activity,cell wall,"cell wall, cell wall organization and biogenesis, structural molecule activity, transport",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,13,6.4,no,,,,, P117,66,F6,P117_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL166C,TPK3,,cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase,"signaling process, mitochondrion organization, protein modification process","transferase activity, protein kinase activity","nucleus, cytoplasm","cytoplasm, nucleus, other, protein kinase activity, protein modification process, signal transduction, transferase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,3,1.3,no,,,,, P117,67,F7,P117_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL167C,MRP49,,"Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation",translation,structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,280,24,8.6,no,,,,, P117,68,F8,P117_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL168C,KKQ8,,Putative serine/threonine protein kinase with unknown cellular role,biological_process,"transferase activity, protein kinase activity",cytoplasm,"biological_process, cytoplasm, protein kinase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,0,0,no,,,,, P117,69,F9,P117_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL171W,NNK1,,"Protein kinase; implicated in proteasome function; interacts with TORC1, Ure2 and Gdh2; overexpression leads to hypersensitivity to rapamycin and nuclear accumulation of Gln3; epitope-tagged protein localizes to the cytoplasm",other,"transferase activity, protein kinase activity",cytoplasm,"cytoplasm, other, protein kinase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,14,6,no,,,,, P117,70,F10,P117_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL174C,TPO5,,Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles,transport,transporter activity,"cytoplasm, Golgi apparatus","Golgi apparatus, transport, transporter activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,241,2,0.8,no,,,,, P117,71,F11,P117_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL175W,ZRT3,,"Vacuolar membrane zinc transporter, transports zinc from storage in the vacuole to the cytoplasm when needed; transcription is induced under conditions of zinc deficiency","transport, cellular homeostasis",transporter activity,"membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, membrane, transport, transporter activity, vacuole",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,247,14,5.7,no,,,,, P117,72,F12,P117_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL176C,LST4,,Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface,"transport, vesicle-mediated transport",transporter activity,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, transport, transporter activity, vesicle-mediated transport",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,7,2.4,no,,,,, P117,73,G1,P117_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL179C,COY1,,Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function,"transport, vesicle-mediated transport",molecular_function,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, membrane, molecular_function, transport, vesicle-mediated transport",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,5,2.2,no,,,,, P117,74,G2,P117_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL183W,LOT5,,Protein of unknown function; gene expression increases in cultures shifted to a lower temperature,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,8,4.5,no,,,,, P117,75,G3,P117_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL184W,SPE1,SPE10;ORD1,"Ornithine decarboxylase, catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines; deletion decreases lifespan, and increases necrotic cell death and ROS generation","cofactor metabolic process, cellular amino acid and derivative metabolic process",lyase activity,cytoplasm,"amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, lyase activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,42,20.2,no,,,,, P117,76,G4,P117_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL185W,ASH1,,"Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate","pseudohyphal growth, transcription, RNA metabolic process","transcription regulator activity, hydrolase activity","cellular bud, nucleus, chromosome","RNA metabolic process, cellular bud, hydrolase activity, nucleus, pseudohyphal growth, transcription, transcription regulator activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,8,2.7,no,,,,, P117,77,G5,P117_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL187C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,4,1.3,no,,,,, P117,78,G6,P117_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL188C,PXA2,PAT1,"Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins",transport,"transporter activity, hydrolase activity","peroxisome, membrane, cytoplasm","cytoplasm, hydrolase activity, membrane, peroxisome, transport, transporter activity",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,255,2,0.8,no,,,,, P117,79,G7,P117_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL190W,CNB1,YCN2;CRV1,"Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1","fungal-type cell wall organization, conjugation, cellular homeostasis, response to chemical stimulus","phosphoprotein phosphatase activity, hydrolase activity",other,"cell wall organization and biogenesis, cellular homeostasis, conjugation, hydrolase activity, other, phosphoprotein phosphatase activity, response to chemical stimulus, signal transduction",,,11_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,219,3,1.4,no,,,,, P117,80,G8,P117_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR027C,RPS25A,rp45;YS23;S31A;S25A;RPS31A,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,294,10,3.4,no,,,,, P117,81,G9,P117_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR031W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,6,2.6,no,,,,, P117,82,G10,P117_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR033C,TIM21,FMP17,Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity,"transport, mitochondrion organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, transport",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,234,14,6,no,,,,, P117,83,G11,P117_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR034W,RPL26B,YL33;L33B;L26B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA",translation,"RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, ribosome, structural molecule activity, translation",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,10,4.4,no,,,,, P117,84,G12,P117_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR035C,,,"Putative protein of unknown function, potential Cdc28p substrate; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,279,7,2.5,no,,,,, P117,85,H1,P117_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR036C,CAX4,CWH8,"Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER, cleaves the anhydride linkage in Dol-P-P, required for Dol-P-P-linked oligosaccharide intermediate synthesis and protein N-glycosylation","cellular carbohydrate metabolic process, protein modification process",hydrolase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, hydrolase activity, membrane, other, protein modification process",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,297,7,2.4,no,,,,, P117,86,H2,P117_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR037C,ACB1,,"Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes; subject to starvation-induced, Grh1p-mediated unconventional secretion","transport, cellular lipid metabolic process","transporter activity, lipid binding","nucleus, extracellular region, cytoplasm","cytoplasm, lipid binding, lipid metabolic process, nucleus, transport, transporter activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,200,9,4.5,no,,,,, P117,87,H3,P117_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P117,88,H4,P117_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR039W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the Autonomously Replicating Sequence ARS722",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,332,12,3.6,no,,,,, P117,89,H5,P117_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR041W,BUD9,,"Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole","cytokinesis, cell cycle",molecular_function,"cellular bud, membrane, site of polarized growth, plasma membrane","anatomical structure morphogenesis, cellular bud, cytokinesis, molecular_function, site of polarized growth",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,185,5,2.7,no,,,,, P117,90,H6,P117_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR042W,,,Putative protein of unknown function; involved in maintenance of proper telomere length; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,334,6,1.8,no,,,,, P117,91,H7,P117_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR043C,NQM1,,Transaldolase of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift,biological_process,transferase activity,nucleus,"biological_process, nucleus, transferase activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,263,8,3,no,,,,, P117,92,H8,P117_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR044C,RME1,CSP1,Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation,"meiosis, transcription, cell cycle, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, meiosis, nucleus, transcription, transcription regulator activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,216,2,0.9,no,,,,, P117,93,H9,P117_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR045C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,3,1.5,no,,,,, P117,94,H10,P117_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR049W,SCM4,,"Potential regulatory effector of CDC4 function, suppresses a temperature-sensitive allele of CDC4, tripartite protein structure in which a charged region separates two uncharged domains, not essential for mitosis or meiosis",cell cycle,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cell cycle, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,13,5.9,no,,,,, P117,95,H11,P117_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR051C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,187,3,1.6,no,,,,, P117,96,H12,P117_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR052W,FMP48,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation",biological_process,transferase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, transferase activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,170,3,1.8,no,,,,, P118,1,A1,P118_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR054W,,,"Eukaryotic initiation factor (eIF) 2A; associates specifically with both 40S subunits and 80 S ribosomes, and interacts genetically with both eIF5b and eIF4E; homologous to mammalian eIF2A",translation,RNA binding,"ribosome, cytoplasm","cytoplasm, ribosome, translation, translation regulator activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,12,5.8,no,,,,, P118,2,A2,P118_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR055W,MUP1,,"High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake",transport,transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,338,4,1.2,no,,,,, P118,3,A3,P118_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR056W,RSC1,,"Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook","response to stress, sporulation resulting in formation of a cellular spore, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, response to stress, sporulation, transcription",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,5,2.7,no,,,,, P118,4,A4,P118_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR057C,LST7,,Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface,"transport, vesicle-mediated transport",transporter activity,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, transport, transporter activity, vesicle-mediated transport",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,244,10,4.1,no,,,,, P118,5,A5,P118_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR058W,PEF1,,"Penta-EF-hand protein required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2","cell budding, cytokinesis, cell cycle",other,"nucleus, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cellular bud, cytokinesis, cytoplasm, nucleus, other, site of polarized growth",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,284,12,4.2,no,,,,, P118,6,A6,P118_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR059W,SPR3,,Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; septin protein involved in sporulation; regulated by ABFI,"fungal-type cell wall organization, response to chemical stimulus, sporulation resulting in formation of a cellular spore, conjugation, cellular component morphogenesis",structural molecule activity,"cell cortex, cytoskeleton, cell wall, cellular bud, membrane, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell cortex, cell wall, cell wall organization and biogenesis, cellular bud, conjugation, cytoplasm, cytoskeleton, membrane, response to chemical stimulus, site of polarized growth, sporulation, structural molecule activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,285,10,3.5,no,,,,, P118,7,A7,P118_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR061C,ADE6,,"Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway",heterocycle metabolic process,ligase activity,cytoplasm,"cytoplasm, ligase activity, other",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,189,12,6.3,no,,,,, P118,8,A8,P118_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR064W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SPT4/YGR063C",other,molecular_function,cellular_component,"cellular_component, molecular_function, other",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,8,2.5,no,,,,, P118,9,A9,P118_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR066C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,332,2,0.6,no,,,,, P118,10,A10,P118_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR067C,,,Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p,biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,242,2,0.8,no,,,,, P118,11,A11,P118_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR068C,ART5,,Protein proposed to regulate the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target in the plasma membrane,"transport, vesicle-mediated transport, cellular membrane organization",protein binding,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,2,0.9,no,,,,, P118,12,A12,P118_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR069W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,330,6,1.8,no,,,,, P118,13,B1,P118_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR070W,ROM1,SKC1,"GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP","fungal-type cell wall organization, cell budding, signaling process, cytoskeleton organization","signal transducer activity, enzyme regulator activity",other,"anatomical structure morphogenesis, cell budding, cell wall organization and biogenesis, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, other, signal transducer activity, signal transduction",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,262,8,3.1,no,,,,, P118,14,B2,P118_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR071C,,,Putative protein of unknown function; deletion mutant has increased glycogen accumulation and displays elongated buds; green fluorescent protein (GFP)-fusion protein localizes to the nucleus,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,287,15,5.2,no,,,,, P118,15,B3,P118_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR072W,UPF3,SUP112;SUA6,"Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p and Nmd2p; involved in decay of mRNA containing nonsense codons; involved in telomere maintenance","protein modification process, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, nucleus, other, protein modification process",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,264,4,1.5,no,,,,, P118,16,B4,P118_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR077C,PEX8,PAS6,"Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal face of the peroxisomal membrane, essential for peroxisome biogenesis, binds PTS1-signal receptor Pex5p","transport, peroxisome organization",other,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, other, peroxisome, transport",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,4,1.4,no,,,,, P118,17,B5,P118_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR078C,PAC10,RKS2;PFD3;GIM2,"Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding",protein complex biogenesis,protein binding,cytoplasm,"cytoplasm, other, protein binding",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,68,22.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P118,18,B6,P118_B6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P118,19,B7,P118_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR079W,,,Putative protein of unknown function; YGR079W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,3,1.8,no,,,,, P118,20,B8,P118_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR080W,TWF1,twinfilin,"Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly","cell budding, cytoskeleton organization, cytokinesis, protein complex biogenesis, cell cycle",protein binding,"cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,342,7,2,no,,,,, P118,21,B9,P118_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR081C,SLX9,,Protein required for pre-rRNA processing; associated with the 90S pre-ribosome and 43S small ribosomal subunit precursor; interacts with U3 snoRNA; deletion mutant has synthetic fitness defect with an sgs1 deletion mutant,"ribosome biogenesis, RNA metabolic process",molecular_function,"nucleus, nucleolus","RNA metabolic process, cytoplasm, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,266,8,3,no,,,,, P118,22,B10,P118_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR084C,MRP13,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,324,4,1.2,no,,,,, P118,23,B11,P118_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR085C,RPL11B,rp39B;YL22;L16B;L11B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11","translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,295,3,1,no,,,,, P118,24,B12,P118_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR087C,PDC6,,"Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino acid catabolism; transcription is glucose- and ethanol-dependent, and is strongly induced during sulfur limitation","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",lyase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, lyase activity, other",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,316,18,5.7,no,,,,, P118,25,C1,P118_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR088W,CTT1,SPS101,"Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide","response to stress, response to chemical stimulus",oxidoreductase activity,cytoplasm,"cytoplasm, oxidoreductase activity, response to chemical stimulus, response to stress",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,6,3,no,,,,, P118,26,C2,P118_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR096W,TPC1,,Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family,transport,transporter activity,"mitochondrial envelope, mitochondrion, cytoplasm","mitochondrial envelope, transport, transporter activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,252,3,1.2,no,,,,, P118,27,C3,P118_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR097W,ASK10,RGC2,"Component of RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p; proposed to function in activation of the glycerol channel Fps1p; paralogous to Rgc1p","transport, response to stress, transcription, response to chemical stimulus",transcription regulator activity,"nucleus, cytoplasm","cytoplasm, nucleus, response to chemical stimulus, response to stress, transcription, transcription regulator activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,197,2,1,no,,,,, P118,28,C4,P118_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR100W,MDR1,GYP2;MIC1,"Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function",transport,enzyme regulator activity,cytoplasm,"cytoplasm, enzyme regulator activity, other, transport",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,24,11.5,no,,,,, P118,29,C5,P118_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR101W,PCP1,RBD1;MDM37,Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases,"transport, mitochondrion organization","peptidase activity, hydrolase activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","mitochondrion, organelle organization and biogenesis, peptidase activity, protein modification process, transport",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,2,1.1,no,,,,, P118,30,C6,P118_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR104C,SRB5,MED18,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, transcription, transcription regulator activity, transposition",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,315,9,2.9,no,,,,, P118,31,C7,P118_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR105W,VMA21,,"Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)",protein complex biogenesis,molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, other",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,27,12.7,no,,,,, P118,32,C8,P118_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR107W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,233,2,0.9,no,,,,, P118,33,C9,P118_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR108W,CLB1,SCB1,"B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome","meiosis, cytoskeleton organization, cell cycle",enzyme regulator activity,"nucleus, cytoplasm","cell cycle, cytoplasm, cytoskeleton organization and biogenesis, enzyme regulator activity, meiosis, nucleus, organelle organization and biogenesis",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,207,19,9.2,no,,,,, P118,34,C10,P118_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR109C,CLB6,,B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1,"cell cycle, DNA metabolic process",enzyme regulator activity,cellular_component,"DNA metabolic process, cell cycle, cellular_component, enzyme regulator activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P118,35,C11,P118_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR111W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,other,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, other",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,199,1,0.5,no,,,,, P118,36,C12,P118_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR112W,SHY1,,Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome,"mitochondrion organization, generation of precursor metabolites and energy, protein complex biogenesis, cellular respiration",protein binding,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, protein binding",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P118,37,D1,P118_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR118W,RPS23A,rp37;YS14;S28A;S23A,"Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal","translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,5,1.6,no,,,,, P118,38,D2,P118_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR121C,MEP1,AMT1,Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation,transport,transporter activity,"membrane, plasma membrane","other, plasma membrane, transport, transporter activity",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,192,19,9.9,no,,,,, P118,39,D3,P118_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR122W,,,"Probable ortholog of A. nidulans PalC, which is involved in pH regulation and binds to the ESCRT-III complex; null mutant does not properly process Rim101p and has decreased resistance to rapamycin; GFP-fusion protein is cytoplasmic","transcription, RNA metabolic process",molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, transcription",,,07_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,9,4.1,no,,,,, P118,40,D4,P118_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR097C,,,Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; YOR097C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,12,4.8,no,,,,, P118,41,D5,P118_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR099W,KTR1,,"Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cell wall organization and biogenesis, protein modification process, transferase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,6,2.9,no,,,,, P118,42,D6,P118_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR100C,CRC1,,"Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation",cellular lipid metabolic process,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, lipid metabolic process, membrane, mitochondrial envelope, mitochondrion, transporter activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,8,3.9,no,,,,, P118,43,D7,P118_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR101W,RAS1,,"GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes","signaling process, heterocycle metabolic process",hydrolase activity,"membrane, plasma membrane","hydrolase activity, other, plasma membrane, signal transduction",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,162,8,4.9,no,,,,, P118,44,D8,P118_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR104W,PIN2,,Protein that induces appearance of [PIN+] prion when overproduced; predicted to be palmitoylated,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,40,13.1,no,,,,, P118,45,D9,P118_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR105W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,11,5.6,no,,,,, P118,46,D10,P118_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR106W,VAM3,PTH1,Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein trafficking; multispecificity vacuolar t-SNARE that mediates docking/fusion of multiple distinct late transport intermediates with the vacuole,"vacuole organization, transport, vesicle organization, vesicle-mediated transport, cellular membrane organization",protein binding,"vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vacuole, vesicle-mediated transport",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,36,12.5,no,,,,, P118,47,D11,P118_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR107W,RGS2,,Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p,signaling process,enzyme regulator activity,"nucleus, cytoplasm","cytoplasm, enzyme regulator activity, nucleus, signal transduction",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,5,2.7,no,,,,, P118,48,D12,P118_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR108W,LEU9,,"Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant",cellular amino acid and derivative metabolic process,transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, transferase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,258,32,12.4,no,,,,, P118,49,E1,P118_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR109W,INP53,SOP2;SJL3,"Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains",cellular lipid metabolic process,hydrolase activity,"cell cortex, membrane fraction, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, hydrolase activity, lipid metabolic process, membrane fraction",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,14,6,no,,,,, P118,50,E2,P118_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR111W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,4,2.3,no,,,,, P118,51,E3,P118_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR112W,CEX1,,"Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p",transport,RNA binding,"nucleus, membrane, endomembrane system, cytoplasm","RNA binding, cytoplasm, endomembrane system, membrane, nucleus, transport",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,36,11.6,no,,,,, P118,52,E4,P118_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR113W,AZF1,,"Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance","transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,26,11.7,no,,,,, P118,53,E5,P118_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR114W,,,Putative protein of unknown function; null mutant is viable,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,10,3.9,no,,,,, P118,54,E6,P118_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR115C,TRS33,,One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic,"transport, vesicle-mediated transport",molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, molecular_function, transport, vesicle-mediated transport",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,18,9,no,,,,, P118,55,E7,P118_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR118W,RTC5,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutation suppresses cdc13-1 temperature sensitivity,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,16,7,no,,,,, P118,56,E8,P118_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR120W,GCY1,GCY,"Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family","response to stress, cellular carbohydrate metabolic process, response to chemical stimulus",oxidoreductase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,10,3.8,no,,,,, P118,57,E9,P118_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR121C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene GCY1/YOR120W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,4,1.2,no,,,,, P118,58,E10,P118_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR123C,LEO1,,"Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition","chromosome organization, transcription, protein modification process, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transcription regulator activity, transposition",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,14,4.7,no,,,,, P118,59,E11,P118_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR124C,UBP2,,Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; interacts with Rsp5p and is required for MVB sorting of membrane proteins; can cleave polyubiquitin and has isopeptidase activity,"protein modification process, cellular protein catabolic process","peptidase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, peptidase activity, protein modification process",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,0,0,no,,,,, P118,60,E12,P118_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR126C,IAH1,,"Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing",other,hydrolase activity,cellular_component,"cellular_component, hydrolase activity, other",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,198,2,1,no,,,,, P118,61,F1,P118_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR129C,AFI1,,"Arf3p polarization-specific docking factor, required for the polarized distribution of the ADP-ribosylation factor, Arf3p; participates in polarity development and maintenance of a normal haploid budding pattern; interacts with Cnm7p","cytokinesis, cell cycle",molecular_function,"cellular bud, nucleus, membrane, site of polarized growth, plasma membrane, cytoplasm","anatomical structure morphogenesis, cellular bud, cytokinesis, cytoplasm, molecular_function, nucleus, other, plasma membrane, site of polarized growth",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,22,6.7,no,,,,, P118,62,F2,P118_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR130C,ORT1,ARG11,"Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome","transport, cellular amino acid and derivative metabolic process",transporter activity,"mitochondrial envelope, mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrial envelope, organelle organization and biogenesis, transport, transporter activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,27,12.2,no,,,,, P118,63,F3,P118_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR131C,,,Putative protein of unknown function; non-essential gene; overexpression causes a cell cycle delay or arrest,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,12,4.8,no,,,,, P118,64,F4,P118_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR132W,VPS17,VPT3;PEP21,Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation,"transport, vesicle-mediated transport","transporter activity, lipid binding","membrane, endomembrane system, cytoplasm","cytoplasm, endomembrane system, lipid binding, membrane, transport, transporter activity, vesicle-mediated transport",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,12,4.8,no,,,,, P118,65,F5,P118_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR133W,EFT1,,"Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin",translation,RNA binding,"ribosome, cytoplasm","ribosome, translation, translation regulator activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,10,3.4,no,,,,, P118,66,F6,P118_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR134W,BAG7,,"Rho GTPase activating protein (RhoGAP), stimulates the intrinsic GTPase activity of Rho1p, which plays a role in actin cytoskeleton organization and control of cell wall synthesis; structurally and functionally related to Sac7p",signaling process,enzyme regulator activity,other,"enzyme regulator activity, other, signal transduction",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,2,1.1,no,,,,, P118,67,F7,P118_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR135C,IRC14,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YOR136W; null mutant displays increased levels of spontaneous Rad52 foci","sporulation resulting in formation of a cellular spore, transcription, DNA metabolic process, RNA metabolic process",molecular_function,cellular_component,"DNA metabolic process, RNA metabolic process, cellular_component, molecular_function, sporulation, transcription",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,66,27.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P118,68,F8,P118_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR136W,IDH2,,"Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated","cofactor metabolic process, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, other, oxidoreductase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,10,5.3,no,,,,, P118,69,F9,P118_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR137C,SIA1,,Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose,transport,molecular_function,cellular_component,"cellular_component, molecular_function, transport",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,18,6.3,no,,,,, P118,70,F10,P118_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR138C,RUP1,,"Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; has a WW domain consensus motif of PPPSY (residues 131-135) that mediates binding of Rsp5p to Ubp2p; contains an UBA domain",protein modification process,protein binding,"nucleus, cytoplasm","cytoplasm, nucleus, protein binding, protein modification process",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,8,4.5,no,,,,, P118,71,F11,P118_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR139C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SFL1/YOR140W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,36,13,no,,,,, P118,72,F12,P118_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR140W,SFL1,,"Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p","transcription, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, chromosome","RNA metabolic process, chromosome, nucleus, transcription, transcription regulator activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,24,11.2,no,,,,, P118,73,G1,P118_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR142W,LSC1,,"Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",ligase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, ligase activity, mitochondrion",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,16,5.8,no,,,,, P118,74,G2,P118_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR144C,ELG1,RTT110,"Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity; involved in homologous recombination-mediated DNA repair","transposition, chromosome segregation, response to stress, chromosome organization, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome, mitochondrion, cytoplasm","DNA metabolic process, chromosome, cytoplasm, mitochondrion, molecular_function, nucleus, organelle organization and biogenesis, response to stress, transposition",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,112,40.9,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P118,75,G3,P118_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR152C,,,Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene,biological_process,molecular_function,membrane fraction,"biological_process, membrane fraction, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,6,2.3,no,,,,, P118,76,G4,P118_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR153W,PDR5,STS1;YDR1;LEM1,"Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth","transport, response to chemical stimulus","hydrolase activity, transporter activity","mitochondrion, membrane, cytoplasm, plasma membrane","hydrolase activity, mitochondrion, plasma membrane, response to chemical stimulus, transport, transporter activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,154,16,10.4,no,,,,, P118,77,G5,P118_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR154W,SLP1,,Integral membrane protein of unknown function; member of the SUN-like family of proteins; genetic interactions suggest a role in folding of ER membrane proteins,protein folding,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,6,1.9,no,,,,, P118,78,G6,P118_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR156C,NFI1,SIZ2,"SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; involved in maintenance of proper telomere length","chromosome organization, protein modification process, chromosome segregation",ligase activity,"nucleus, chromosome, cytoplasm","chromosome, cytoplasm, ligase activity, nucleus, organelle organization and biogenesis, other, protein modification process",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,235,17,7.2,no,,,,, P118,79,G7,P118_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR161C,PNS1,,"Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport",biological_process,molecular_function,"membrane, membrane fraction, plasma membrane","biological_process, membrane, molecular_function, plasma membrane",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,26,10.5,no,,,,, P118,80,G8,P118_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR162C,YRR1,PDR2,"Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes","transport, transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, nucleus, response to chemical stimulus, transcription, transcription regulator activity, transport",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,28,10,no,,,,, P118,81,G9,P118_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR163W,DDP1,,Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases,"cellular carbohydrate metabolic process, heterocycle metabolic process",hydrolase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, hydrolase activity, nucleus, other",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,12,5.2,no,,,,, P118,82,G10,P118_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR164C,GET4,,Protein with a role in insertion of tail-anchored proteins into the ER membrane; forms a complex with Mdy2p; highly conserved across species and homologous to human gene C7orf20,"transport, cellular membrane organization",molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,28,9.9,no,,,,, P118,83,G11,P118_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR165W,SEY1,,"GTPase with a role in ER morphology; interacts physically and genetically with Yop1p and Rtn1p; possible functional ortholog of mammalian atlastins, defects in which cause a form of hereditary spastic paraplegia; homolog of Arabidopsis RHD3",cellular membrane organization,hydrolase activity,"cell cortex, endoplasmic reticulum, cytoplasm","cytoplasm, membrane organization and biogenesis, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,20,9.4,no,,,,, P118,84,G12,P118_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR166C,SWT1,,"RNA endoribonuclease involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain","transcription, RNA metabolic process",hydrolase activity,"nucleus, cytoplasm","RNA metabolic process, molecular_function, nucleus, transcription",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,13,6.9,no,,,,, P118,85,H1,P118_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR167C,RPS28A,YS27;S33A;S28A;RPS33A,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Bp and has similarity to rat S28 ribosomal protein,"transport, translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,10,6.3,no,,,,, P118,86,H2,P118_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR170W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene LCB4",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,18,8.3,no,,,,, P118,87,H3,P118_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P118,88,H4,P118_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR171C,LCB4,,"Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes","signaling process, cellular lipid metabolic process",transferase activity,"cell cortex, membrane fraction, membrane, endoplasmic reticulum, Golgi apparatus, cytoplasm, plasma membrane","Golgi apparatus, cytoplasm, endoplasmic reticulum, lipid metabolic process, membrane fraction, other, plasma membrane, signal transduction, transferase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,6,2.4,no,,,,, P118,89,H5,P118_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR172W,YRM1,,"Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes","transport, transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, response to chemical stimulus, transcription, transcription regulator activity, transport",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,22,8,no,,,,, P118,90,H6,P118_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR173W,DCS2,,"Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, similar to Dcs1p.",RNA metabolic process,hydrolase activity,cytoplasm,"RNA metabolic process, cytoplasm, hydrolase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,10,3,no,,,,, P118,91,H7,P118_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR175C,ALE1,LCA1;LPT1;SLC4,"Broad-specificity lysophospholipid acyltransferase, part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids",cellular lipid metabolic process,transferase activity,"membrane fraction, ribosome, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, membrane fraction, ribosome, transferase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,2,0.9,no,,,,, P118,92,H8,P118_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR177C,MPC54,,"Component of the meiotic outer plaque, a membrane-organizing center which is assembled on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; potential Cdc28p substrate","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",structural molecule activity,"cytoskeleton, microtubule organizing center, cytoplasm","cell wall organization and biogenesis, cytoplasm, cytoskeleton, microtubule organizing center, sporulation, structural molecule activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,15,7.2,no,,,,, P118,93,H9,P118_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR178C,GAC1,,"Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock","signaling process, transcription, generation of precursor metabolites and energy, response to stress, meiosis, cellular carbohydrate metabolic process, cell cycle, RNA metabolic process","enzyme regulator activity, structural molecule activity, protein binding",cytoplasm,"RNA metabolic process, carbohydrate metabolic process, cell cycle, cytoplasm, enzyme regulator activity, generation of precursor metabolites and energy, meiosis, protein binding, response to stress, structural molecule activity, transcription",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,274,52,19,no,,,,, P118,94,H10,P118_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR179C,SYC1,,"Subunit of the APT subcomplex of cleavage and polyadenylation factor, may have a role in 3' end formation of both polyadenylated and non-polyadenylated RNAs","transcription, RNA metabolic process",RNA binding,nucleus,"RNA binding, RNA metabolic process, nucleus, transcription",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,5,2.2,no,,,,, P118,95,H11,P118_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR180C,DCI1,ECI2,"Peroxisomal protein; identification as a delta(3,5)-delta(2,4)-dienoyl-CoA isomerase involved in fatty acid metabolism is disputed",cellular lipid metabolic process,not_yet_annotated,"peroxisome, cytoplasm","cytoplasm, isomerase activity, lipid metabolic process, peroxisome",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,194,25,12.9,no,,,,, P118,96,H12,P118_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR182C,RPS30B,S30B,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Ap and has similarity to rat S30 ribosomal protein,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,20,10.9,no,,,,, P119,1,A1,P119_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR183W,FYV12,,"Protein of unknown function, required for survival upon exposure to K1 killer toxin",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,7,3.2,no,,,,, P119,2,A2,P119_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR184W,SER1,ADE9,"3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, transferase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,34,15.5,no,,,,, P119,3,A3,P119_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR185C,GSP2,CNR2,"GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability",nucleus organization,hydrolase activity,nucleus,"hydrolase activity, nuclear organization and biogenesis, nucleus",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,12,5.7,no,,,,, P119,4,A4,P119_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR186W,,,Putative protein of unknown function; proper regulation of expression during heat stress is sphingolipid-dependent,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,231,14,6.1,no,,,,, P119,5,A5,P119_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR188W,MSB1,,"Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway, potential Cdc28p substrate; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4",other,molecular_function,"cellular bud, site of polarized growth, mitochondrion, cytoplasm","anatomical structure morphogenesis, cellular bud, mitochondrion, molecular_function, site of polarized growth",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,26,8,no,,,,, P119,6,A6,P119_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR189W,IES4,,Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses,response to stress,molecular_function,"nucleus, chromosome","molecular_function, nucleus, response to stress",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,10,3.1,no,,,,, P119,7,A7,P119_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR190W,SPR1,SSG1,"Sporulation-specific exo-1,3-beta-glucanase; contributes to ascospore thermoresistance",sporulation resulting in formation of a cellular spore,hydrolase activity,cell wall,"cell wall, hydrolase activity, sporulation",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,241,23,9.5,no,,,,, P119,8,A8,P119_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR191W,ULS1,RIS1;TID4;DIS1,RING finger protein involved in proteolytic control of sumoylated substrates; interacts with SUMO (Smt3p); member of the SWI/SNF family of DNA-dependent ATPases; plays a role in antagonizing silencing during mating-type switching,"chromosome organization, DNA metabolic process","protein binding, hydrolase activity","nucleus, nucleolus, mitochondrion, cytoplasm","DNA metabolic process, hydrolase activity, mitochondrion, nucleolus, nucleus, organelle organization and biogenesis, protein binding",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,12,5.7,no,,,,, P119,9,A9,P119_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR192C,THI72,,Transporter of thiamine or related compound; shares sequence similarity with Thi7p,transport,transporter activity,membrane,"membrane, transport, transporter activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,27,14.6,no,,,,, P119,10,A10,P119_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR193W,PEX27,,"Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number, interacts with homologous protein Pex25p",peroxisome organization,molecular_function,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, molecular_function, organelle organization and biogenesis, peroxisome",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,10,5.1,no,,,,, P119,11,A11,P119_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR195W,SLK19,,"Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate","meiosis, cytoskeleton organization, cell cycle",molecular_function,"nucleus, cytoskeleton, chromosome","cell cycle, chromosome, cytoskeleton, cytoskeleton organization and biogenesis, meiosis, molecular_function, nucleus, organelle organization and biogenesis",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,5,2.4,no,,,,, P119,12,A12,P119_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR196C,LIP5,,"Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to E. coli lipoic acid synthase",protein modification process,"transferase activity, ligase activity","mitochondrion, cytoplasm","cofactor metabolic process, heterocycle metabolic process, mitochondrion, other",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,3,1.4,no,,,,, P119,13,B1,P119_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR197W,MCA1,YCA1,Putative cysteine protease similar to mammalian caspases; involved in regulation of apoptosis upon hydrogen peroxide treatment; proposed to be involved in cell cycle progression,"response to stress, response to chemical stimulus","peptidase activity, hydrolase activity",nucleus,"hydrolase activity, nucleus, other, peptidase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,11,5.9,no,,,,, P119,14,B2,P119_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR198C,BFR1,,Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity,"meiosis, cell cycle, RNA metabolic process",RNA binding,"membrane, endomembrane system","RNA binding, RNA metabolic process, cell cycle, endomembrane system, meiosis, membrane, other",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,39,16.8,no,,,,, P119,15,B3,P119_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR199W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,1,0.5,no,,,,, P119,16,B4,P119_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR200W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MRM1/YOR201c",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,16,6.4,no,,,,, P119,17,B5,P119_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR201C,MRM1,PET56,"Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA","ribosome biogenesis, RNA metabolic process",transferase activity,"mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, organelle organization and biogenesis, ribosome biogenesis, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,6,2.8,no,,,,, P119,18,B6,P119_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR202W,HIS3,HIS8;HIS10,"Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p","cellular amino acid and derivative metabolic process, heterocycle metabolic process",lyase activity,cellular_component,"amino acid and derivative metabolic process, cellular_component, lyase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,34,10.3,no,,,,, P119,19,B7,P119_B7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P119,20,B8,P119_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR205C,GEP3,AIM40;LRC5;FMP38,"Protein of unknown function; null mutant is defective in respiration and interacts synthetically with prohibitin (phb1); the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,334,16,4.8,no,,,,, P119,21,B9,P119_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR208W,PTP2,,Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus,"signaling process, response to chemical stimulus, protein modification process, response to stress, conjugation","hydrolase activity, phosphoprotein phosphatase activity",nucleus,"conjugation, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process, response to chemical stimulus, response to stress, signal transduction",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,10,4.4,no,,,,, P119,22,B10,P119_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR209C,NPT1,,"Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus","cofactor metabolic process, transcription, vitamin metabolic process, RNA metabolic process",transferase activity,nucleus,"RNA metabolic process, cofactor metabolic process, nucleus, organelle organization and biogenesis, other, transcription, transferase activity, vitamin metabolic process",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,6,1.9,no,,,,, P119,23,B11,P119_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR213C,SAS5,,"Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; stimulates Sas2p HAT activity","transcription, RNA metabolic process",transferase activity,"nucleus, chromosome","RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, transcription, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,39,14.6,no,,,,, P119,24,B12,P119_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR214C,,,Putative protein of unknown function; YOR214C is not an essential gene,biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,8,4.6,no,,,,, P119,25,C1,P119_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR215C,AIM41,,Putative protein of unknown function; the authentic protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,451,6,1.3,no,,,,, P119,26,C2,P119_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR216C,RUD3,GRP1,Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1,"transport, vesicle-mediated transport",molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, molecular_function, transport, vesicle-mediated transport",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,1,0.5,no,,,,, P119,27,C3,P119_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR219C,STE13,YCI1,"Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor",other,"peptidase activity, hydrolase activity","cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, hydrolase activity, peptidase activity, protein modification process",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P119,28,C4,P119_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR220W,RCN2,WSP1,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; phosphorylated in response to alpha factor,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,2,1.1,no,,,,, P119,29,C5,P119_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR221C,MCT1,,"Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling","cellular lipid metabolic process, generation of precursor metabolites and energy, cellular respiration",transferase activity,"mitochondrion, cytoplasm","cellular respiration, generation of precursor metabolites and energy, lipid metabolic process, mitochondrion, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,9,4.9,no,,,,, P119,30,C6,P119_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR222W,ODC2,2-oxodicarboxylate transporter,"Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,36,17.5,no,,,,, P119,31,C7,P119_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR223W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,2,0.9,no,,,,, P119,32,C8,P119_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR225W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,20,11.6,no,,,,, P119,33,C9,P119_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR226C,ISU2,NUA2,"Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable","cofactor metabolic process, cellular homeostasis, RNA metabolic process",molecular_function,"mitochondrion, cytoplasm","cellular homeostasis, cofactor metabolic process, cytoplasm, mitochondrion, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,4,1.4,no,,,,, P119,34,C10,P119_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR227W,HER1,,"Protein of unknown function required for proliferation or remodeling of the ER that is caused by overexpression of Hmg2p; may interact with ribosomes, based on co-purification experiments",other,molecular_function,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, molecular_function, organelle organization and biogenesis, ribosome",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,5,2.7,no,,,,, P119,35,C11,P119_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR228C,,,"Protein of unknown function, localized to the mitochondrial outer membrane",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,21,8.4,no,,,,, P119,36,C12,P119_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR229W,WTM2,,"Transcriptional modulator involved in regulation of meiosis, silencing, and expression of RNR genes; involved in response to replication stress; contains WD repeats","transcription, response to stress, meiosis, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding, protein binding",nucleus,"DNA binding, RNA metabolic process, cell cycle, meiosis, nucleus, protein binding, response to stress, transcription, transcription regulator activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,6,3.4,no,,,,, P119,37,D1,P119_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR230W,WTM1,,"Transcriptional modulator involved in regulation of meiosis, silencing, and expression of RNR genes; required for nuclear localization of the ribonucleotide reductase small subunit Rnr2p and Rnr4p; contains WD repeats","transport, meiosis, transcription, cell cycle, RNA metabolic process","transcription regulator activity, protein binding",nucleus,"RNA metabolic process, cell cycle, meiosis, nucleus, protein binding, transcription, transcription regulator activity, transport",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,37,18.9,no,,,,, P119,38,D2,P119_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR231W,MKK1,SSP32,"Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p","signaling process, peroxisome organization, protein modification process","transferase activity, protein kinase activity","cellular bud, site of polarized growth","cellular bud, protein kinase activity, protein modification process, signal transduction, site of polarized growth, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,14,6.1,no,,,,, P119,39,D3,P119_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR233W,KIN4,KIN3;KIN31,"Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck","signaling process, protein modification process, cell cycle","transferase activity, protein kinase activity","cell cortex, cytoskeleton, microtubule organizing center, cellular bud, site of polarized growth, cytoplasm","cell cortex, cell cycle, cellular bud, cytoplasm, cytoskeleton, microtubule organizing center, protein kinase activity, protein modification process, site of polarized growth, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,2,0.8,no,,,,, P119,40,D4,P119_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR234C,RPL33B,rp47;Yl37;L37B;L33B;RPL37B,"Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,6,3.5,no,,,,, P119,41,D5,P119_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR235W,IRC13,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays increased levels of spontaneous Rad52 foci",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,242,64,26.4,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P119,42,D6,P119_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR237W,HES1,OSH5,Protein implicated in the regulation of ergosterol biosynthesis; one of a seven member gene family with a common essential function and non-essential unique functions; similar to human oxysterol binding protein (OSBP),"transport, vesicle-mediated transport, cellular membrane organization","transporter activity, lipid binding",cellular_component,"anatomical structure morphogenesis, cellular_component, lipid binding, membrane organization and biogenesis, transport, vesicle-mediated transport",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,28,8.8,no,,,,, P119,43,D7,P119_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR238W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,4,1.2,no,,,,, P119,44,D8,P119_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR239W,ABP140,YOR240W,"Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases",cytoskeleton organization,"transferase activity, protein binding","site of polarized growth, cytoskeleton","cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,3,1.5,no,,,,, P119,45,D9,P119_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR239W,ABP140,YOR240W,"Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases",cytoskeleton organization,"transferase activity, protein binding","site of polarized growth, cytoskeleton","cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,4,1.5,no,,,,, P119,46,D10,P119_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR242C,SSP2,,Sporulation specific protein that localizes to the spore wall; required for sporulation at a point after meiosis II and during spore wall formation; SSP2 expression is induced midway in meiosis,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,cell wall,"cell wall, cell wall organization and biogenesis, molecular_function, sporulation",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,251,2,0.8,no,,,,, P119,47,D11,P119_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR243C,PUS7,,"Pseudouridine synthase, catalyzes pseudouridylation at position 35 in U2 snRNA, position 50 in 5S rRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); conserved in archaea, vertebrates, and some bacteria","ribosome biogenesis, RNA metabolic process",isomerase activity,nucleus,"RNA metabolic process, isomerase activity, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,12,4.3,no,,,,, P119,48,D12,P119_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR245C,DGA1,,"Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles",cellular lipid metabolic process,transferase activity,cytoplasm,"cytoplasm, lipid metabolic process, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,15,7.7,no,,,,, P119,49,E1,P119_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR246C,,,"Protein with similarity to oxidoreductases, found in lipid particles; required for replication of Brome mosaic virus in S. cerevisiae, a model system for studying replication of positive-strand RNA viruses in their natural hosts",biological_process,oxidoreductase activity,cytoplasm,"biological_process, cytoplasm, oxidoreductase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,17,8.9,no,,,,, P119,50,E2,P119_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR247W,SRL1,,"Mannoprotein that exhibits a tight association with the cell wall, required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants",fungal-type cell wall organization,molecular_function,"cellular bud, cell wall, site of polarized growth, vacuole, cytoplasm","cell wall, cellular bud, cytoplasm, molecular_function, other, site of polarized growth, vacuole",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,0,0,no,,,,, P119,51,E3,P119_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR248W,,TOS11,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,243,1,0.4,no,,,,, P119,52,E4,P119_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR251C,TUM1,,"Mitochondrial protein, required for formation of the 2-thio group of the 5-methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs; has similarity to mammalian thiosulfate sulfurtransferase (rhodanese)",RNA metabolic process,transferase activity,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,2,0.6,no,,,,, P119,53,E5,P119_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR252W,TMA16,RBF17,Protein of unknown function that associates with ribosomes,biological_process,molecular_function,"nucleus, ribosome, cytoplasm","biological_process, molecular_function, nucleus, ribosome",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,32,10.3,no,,,,, P119,54,E6,P119_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR253W,NAT5,NAA50;ROG2;ARD2,"Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing",protein modification process,transferase activity,"ribosome, cytoplasm","cytoplasm, protein modification process, ribosome, transferase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,3,1.5,no,,,,, P119,55,E7,P119_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR255W,OSW1,,Protein involved in sporulation; required for the construction of the outer spore wall layers; required for proper localization of Spo14p,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,membrane,"cell wall organization and biogenesis, membrane, molecular_function, sporulation",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,9,5.1,no,,,,, P119,56,E8,P119_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR258W,HNT3,,"DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins; homolog of Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia",response to stress,hydrolase activity,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,4,1.5,no,,,,, P119,57,E9,P119_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR263C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF DES3/YOR264W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,2,0.7,no,,,,, P119,58,E10,P119_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR264W,DSE3,,"Daughter cell-specific protein, may help establish daughter fate",biological_process,molecular_function,"cellular bud, site of polarized growth","biological_process, cellular bud, molecular_function, site of polarized growth",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,14,7.1,no,,,,, P119,59,E11,P119_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR277C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene CAF20",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,2,0.7,no,,,,, P119,60,E12,P119_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR279C,RFM1,,DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance,"transcription, RNA metabolic process",protein binding,nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein binding, transcription",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,16,4.9,no,,,,, P119,61,F1,P119_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR280C,FSH3,,Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence is similar to S. cerevisiae Fsh1p and Fsh2p and the human candidate tumor suppressor OVCA2,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, hydrolase activity",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,237,41,17.3,no,,,,, P119,62,F2,P119_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR283W,,,"Phosphatase with a broad substrate specificity and some similarity to GPM1/YKL152C, a phosphoglycerate mutase; YOR283W is not an essential gene",other,hydrolase activity,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,10,5,no,,,,, P119,63,F3,P119_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR284W,HUA2,,Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly,biological_process,molecular_function,cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,2,0.9,no,,,,, P119,64,F4,P119_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR285W,RDL1,,Protein of unknown function containing a rhodanese-like domain; localized to the mitochondrial outer membrane,biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endoplasmic reticulum, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,6,1.9,no,,,,, P119,65,F5,P119_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR286W,RDL2,AIM42;FMP31,"Protein with rhodanese activity; contains a rhodanese-like domain similar to Rdl1p, Uba4p, Tum1p, and Ych1p; overexpression causes a cell cycle delay; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,transferase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,12,4.1,no,,,,, P119,66,F6,P119_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR288C,MPD1,,Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation,protein folding,"isomerase activity, oxidoreductase activity","vacuole, cytoplasm","cytoplasm, isomerase activity, oxidoreductase activity, protein folding, vacuole",,,15_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,3,1.5,no,,,,, P119,67,F7,P119_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL218W,,,"Putative protein of unknown function, similar to bacterial galactoside O-acetyltransferases; induced by oleate in an OAF1/PIP2-dependent manner; promoter contains an oleate response element consensus sequence; non-essential gene",biological_process,transferase activity,cellular_component,"biological_process, cellular_component, transferase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,28,8.5,no,,,,, P119,68,F8,P119_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL217W,REE1,,"Cytoplasmic protein involved in the regulation of enolase (ENO1); mRNA expression is induced by calcium shortage, copper deficiency (via Mac1p) and the presence of galactose (via Gal4p); mRNA expression is also regulated by the cell cycle",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,5,2.7,no,,,,, P119,69,F9,P119_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL216C,IMA5,,"Alpha-glucosidase with specificity for isomaltose, maltose, and palatinose; member of the IMA isomaltase family; not required for isomaltose utilization, but Ima5p overexpression allows the ima1 null mutant to grow on isomaltose",cellular carbohydrate metabolic process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,7,3.5,no,,,,, P119,70,F10,P119_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL215C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,34,10.1,no,,,,, P119,71,F11,P119_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL214W,HXT8,,"Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,14,5.9,no,,,,, P119,72,F12,P119_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL212C,OPT1,GSH11;HGT1,Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family,transport,transporter activity,"membrane, plasma membrane","endoplasmic reticulum, membrane, other, plasma membrane, transport, transporter activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,7,4.1,no,,,,, P119,73,G1,P119_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL210W,PEX2,PAS5;CRT1,"RING-finger peroxin and E3 ubiquitin ligase, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import","transport, peroxisome organization","protein binding, ligase activity","peroxisome, membrane, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, peroxisome, protein binding, transport",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,7,3,no,,,,, P119,74,G2,P119_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL211C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL210W/PEX2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,1,0.5,no,,,,, P119,75,G3,P119_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL208C,NUC1,,"Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy","DNA metabolic process, RNA metabolic process",hydrolase activity,"nucleus, mitochondrion, membrane, mitochondrial envelope, cytoplasm","DNA metabolic process, RNA metabolic process, cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, nucleus, other, ribosome biogenesis",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,42,13,no,,,,, P119,76,G4,P119_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL207C,LAA1,,AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene,"transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, ribosome, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, other, ribosome, transport, vesicle-mediated transport",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,38,17.8,no,,,,, P119,77,G5,P119_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL199C,MBB1,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,12,3.6,no,,,,, P119,78,G6,P119_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL198W,PHO90,,"Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,16,7.6,no,,,,, P119,79,G7,P119_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL197W,UBP12,,"Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease present in the nucleus and cytoplasm that cleaves ubiquitin from ubiquitinated proteins",biological_process,"peptidase activity, hydrolase activity","nucleus, cytoplasm","biological_process, cytoplasm, hydrolase activity, nucleus, peptidase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,281,0,0,no,,,,, P119,80,G8,P119_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL193W,,,"Putative protein of unknown function, predicted to encode a triose phosphate transporter subfamily member based on phylogenetic analysis; similar to YOR307C/SLY41; deletion mutant has a respiratory growth defect",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,32,16.4,no,,,,, P119,81,G9,P119_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL192C,SOP4,,"ER-membrane protein; suppressor of pma1-7, deletion of SOP4 slows down the export of wild-type Pma1p and Pma1-7 from the ER","transport, vesicle-mediated transport",molecular_function,"membrane fraction, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, membrane fraction, molecular_function, transport, vesicle-mediated transport",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,27,11.5,no,,,,, P119,82,G10,P119_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL190C,RPS22A,rp50;YS22;S24A;S22A;RPS24,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,4,2.1,no,,,,, P119,83,G11,P119_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL188C,BUD19,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 88% of ORF overlaps the verified gene RPL39; diploid mutant displays a weak budding pattern phenotype in a systematic assay","cytokinesis, cell cycle",molecular_function,cellular_component,"anatomical structure morphogenesis, cellular_component, cytokinesis, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,152,18,11.8,no,,,,, P119,84,G12,P119_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL187C,SWE1,WEE1,Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate,"signaling process, cytoskeleton organization, meiosis, cell cycle","transferase activity, protein kinase activity","nucleus, cellular bud, site of polarized growth","anatomical structure morphogenesis, cell cycle, cellular bud, meiosis, nucleus, other, protein kinase activity, site of polarized growth",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,33,13.1,no,,,,, P119,85,H1,P119_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL186W,MNN5,,"Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, protein modification process, transferase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,7,3.9,no,,,,, P119,86,H2,P119_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL185C,,,"Putative protein of unknown function; mRNA is weakly cell cycle regulated, peaking in G2 phase; YJL185C is a non-essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,6,2.5,no,,,,, P119,87,H3,P119_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P119,88,H4,P119_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL183W,MNN11,,"Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, protein modification process, transferase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,28,9.3,no,,,,, P119,89,H5,P119_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL181W,,,Putative protein of unknown function; expression is cell-cycle regulated as shown by microarray analysis,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,32,10.7,no,,,,, P119,90,H6,P119_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL182C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YJL181W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,45,25.6,no,,,,, P119,91,H7,P119_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL179W,PFD1,GIM6,"Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin","protein folding, cytoskeleton organization",protein binding,cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, protein binding, protein folding",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,42,18.3,no,,,,, P119,92,H8,P119_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL178C,ATG27,ETF1,Type I membrane protein involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; may be involved in membrane delivery to the phagophore assembly site,"vacuole organization, transport, vesicle organization, peroxisome organization, response to stress",lipid binding,"mitochondrion, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, lipid binding, membrane, mitochondrion, organelle organization and biogenesis, other, response to stress, transport",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,14,7.7,no,,,,, P119,93,H9,P119_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL176C,SWI3,TYE2,"Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2","chromosome organization, transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,15,8.5,no,,,,, P119,94,H10,P119_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL171C,,,"GPI-anchored cell wall protein of unknown function; induced in response to cell wall damaging agents and by mutations in genes involved in cell wall biogenesis; sequence similarity to YBR162C/TOS1, a covalently bound cell wall protein",biological_process,molecular_function,"cell wall, membrane fraction, mitochondrion, cytoplasm","biological_process, cell wall, mitochondrion, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,25,11.5,no,,,,, P119,95,H11,P119_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL170C,ASG7,,Protein that regulates signaling from a G protein beta subunit Ste4p and its relocalization within the cell; specific to a-cells and induced by alpha-factor,conjugation,molecular_function,"membrane, plasma membrane","conjugation, molecular_function, plasma membrane",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,14,5.8,no,,,,, P119,96,H12,P119_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL169W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL168C/SET2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,185,53,28.6,no,,,,, P120,1,A1,P120_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL168C,SET2,KMT3;EZL1,"Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p","transcription, protein modification process, meiosis, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process",transferase activity,nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, sporulation, transcription, transferase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,36,18.6,no,,,,, P120,2,A2,P120_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL166W,QCR8,COR5,"Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,32,14,no,,,,, P120,3,A3,P120_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL164C,TPK1,SRA3;PKA1,cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p,"signaling process, protein modification process","transferase activity, protein kinase activity","nucleus, cytoplasm","cytoplasm, nucleus, other, protein kinase activity, protein modification process, signal transduction, transferase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,22,7.9,no,,,,, P120,4,A4,P120_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL162C,JJJ2,,"Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,24,11.3,no,,,,, P120,5,A5,P120_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL160C,,,"Putative protein of unknown function; member of the PIR (proteins with internal repeats) family of cell wall proteins; non-essential gene that is required for sporulation; mRNA is weakly cell cycle regulated, peaking in mitosis",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,251,33,13.1,no,,,,, P120,6,A6,P120_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL159W,HSP150,PIR2;ORE1;CCW7,"O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation",fungal-type cell wall organization,structural molecule activity,"cell wall, extracellular region","cell wall, cell wall organization and biogenesis, structural molecule activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,8,4.3,no,,,,, P120,7,A7,P120_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL158C,CIS3,CCW5;PIR4;CCW11,Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family,fungal-type cell wall organization,structural molecule activity,"cell wall, cellular bud, extracellular region, membrane, site of polarized growth, endoplasmic reticulum, cytoplasm, plasma membrane","cell wall, cell wall organization and biogenesis, cellular bud, endoplasmic reticulum, extracellular region, plasma membrane, site of polarized growth, structural molecule activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,26,13,no,,,,, P120,8,A8,P120_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL157C,FAR1,,"Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate","signaling process, response to chemical stimulus, conjugation, cell cycle",enzyme regulator activity,"nucleus, membrane, site of polarized growth, cytoplasm","cell cycle, conjugation, cytoplasm, enzyme regulator activity, membrane, nucleus, response to chemical stimulus, signal transduction, site of polarized growth",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P120,9,A9,P120_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL155C,FBP26,,"Fructose-2,6-bisphosphatase, required for glucose metabolism",cellular carbohydrate metabolic process,"transferase activity, hydrolase activity",cytoplasm,"carbohydrate metabolic process, cytoplasm, hydrolase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,39,21.4,no,,,,, P120,10,A10,P120_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL154C,VPS35,VPT7;GRD9,"Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval","transport, vesicle-mediated transport","transporter activity, protein binding","membrane, endomembrane system, cytoplasm","cytoplasm, endomembrane system, membrane, other, protein binding, transport, transporter activity, vesicle-mediated transport",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,10,4.7,no,,,,, P120,11,A11,P120_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL153C,INO1,APR1,"Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element",cellular carbohydrate metabolic process,isomerase activity,cytoplasm,"cytoplasm, isomerase activity, other",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,30,12.7,no,,,,, P120,12,A12,P120_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL152W,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,50,17.5,no,,,,, P120,13,B1,P120_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL150W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,18,8.7,no,,,,, P120,14,B2,P120_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL149W,DAS1,,Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C,biological_process,molecular_function,other,"biological_process, molecular_function, other",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,24,9.5,no,,,,, P120,15,B3,P120_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL148W,RPA34,A34.5,RNA polymerase I subunit A34.5,"transcription, RNA metabolic process",molecular_function,"nucleus, nucleolus","RNA metabolic process, nucleolus, nucleotidyltransferase activity, nucleus, ribosome biogenesis, transcription, transferase activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,9,4.9,no,,,,, P120,16,B4,P120_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL147C,,,Mitochondrial protein of unknown function; homozygous diploid deletion strain has a sporulation defect characterized by elevated dityrosine in the soluble fraction; expression induced by calcium shortage; YJL147W is a non-essential gene,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,26,8.9,no,,,,, P120,17,B5,P120_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL146W,IDS2,,"Protein involved in modulation of Ime2p activity during meiosis, appears to act indirectly to promote Ime2p-mediated late meiotic functions; found in growing cells and degraded during sporulation","meiosis, cell cycle",molecular_function,"nucleus, cytoplasm","cytoplasm, meiosis, molecular_function, nucleus",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,34,12.6,no,,,,, P120,18,B6,P120_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL145W,SFH5,,"Non-classical phosphatidylinositol transfer protein (PITP); exhibits PI- but not PC-transfer activity; localizes to the peripheral endoplasmic reticulum, cytosol and microsomes; similar to Sec14p",transport,transporter activity,"cell cortex, membrane fraction, endoplasmic reticulum, cytoplasm","cytoplasm, membrane fraction, transport, transporter activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,44,16.9,no,,,,, P120,19,B7,P120_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL144W,,,"Cytoplasmic hydrophilin of unknown function, possibly involved in the dessication response; expression induced by osmotic stress, starvation and during stationary phase; GFP-fusion protein is induced by the DNA-damaging agent MMS","response to stress, response to chemical stimulus",molecular_function,cytoplasm,"cytoplasm, molecular_function, response to stress",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,6,1.8,no,,,,, P120,20,B8,P120_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P120,21,B9,P120_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL142C,IRC9,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene YJL141C; null mutant displays increased levels of spontaneous Rad52p foci",DNA metabolic process,molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,44,20.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P120,22,B10,P120_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL135W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified genes YJL134W/LCB3",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,18,7.1,no,,,,, P120,23,B11,P120_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL134W,LCB3,YSR2;LBP1,"Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids","signaling process, cellular lipid metabolic process",hydrolase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, lipid metabolic process, signal transduction",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,36,13.5,no,,,,, P120,24,B12,P120_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL133W,MRS3,,"Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs4p; active under low-iron conditions; may transport other cations","transport, RNA metabolic process",transporter activity,"mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,14,4.2,no,,,,, P120,25,C1,P120_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL132W,,,Putative protein of unknown function; localizes to the membrane fraction; possible Zap1p-regulated target gene induced by zinc deficiency; YJL132W is a non-essential gene,biological_process,molecular_function,membrane fraction,"biological_process, membrane fraction, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,9,4,no,,,,, P120,26,C2,P120_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL131C,AIM23,,"Putative protein of unknown function; the authentic non-tagged protein is detected in highly purified mitochondria; null mutant is viable, displays severe respiratory growth defect and elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,54,23.5,no,,,,, P120,27,C3,P120_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL129C,TRK1,,"Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation",cellular homeostasis,transporter activity,membrane,"cellular homeostasis, membrane, transporter activity",,,10_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,237,12,5.1,no,,,,, P120,28,C4,P120_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR324W,PEX30,,"Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p",peroxisome organization,molecular_function,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, molecular_function, organelle organization and biogenesis, peroxisome",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,2,0.6,no,,,,, P120,29,C5,P120_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR325C,RPL38,L38,"Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,24,10.5,no,,,,, P120,30,C6,P120_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR326W,,,"Putative protein of unknown function, predicted to be palmitoylated",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,18,8,no,,,,, P120,31,C7,P120_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR327C,TMA10,RBF9;SFL2,Protein of unknown function that associates with ribosomes; putative homolog of the F1F0-ATPase synthase regulator Stf2p,biological_process,molecular_function,"nucleus, ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus, ribosome",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,2,0.8,no,,,,, P120,32,C8,P120_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR328W,NMA1,,"Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways",cofactor metabolic process,"transferase activity, nucleotidyltransferase activity","nucleus, cytoplasm","cofactor metabolic process, cytoplasm, nucleotidyltransferase activity, nucleus, transferase activity, vitamin metabolic process",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,2,1,no,,,,, P120,33,C9,P120_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR329W,REC102,,Protein involved in early stages of meiotic recombination; required for chromosome synapsis; forms a complex with Rec104p and Spo11p necessary during the initiation of recombination,"meiosis, cell cycle, DNA metabolic process",protein binding,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, nucleus, protein binding",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,10,3,no,,,,, P120,34,C10,P120_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR330W,CHS5,CAL3,"Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane","transport, cytokinesis, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, conjugation, cellular component morphogenesis, cell cycle",molecular_function,"endomembrane system, cytoplasmic membrane-bounded vesicle, membrane, site of polarized growth, Golgi apparatus, cytoplasm","Golgi apparatus, anatomical structure morphogenesis, carbohydrate metabolic process, cell wall organization and biogenesis, conjugation, cytokinesis, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, sporulation, transport, vesicle-mediated transport",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,4,2,no,,,,, P120,35,C11,P120_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR331C,JIP3,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,10,5,no,,,,, P120,36,C12,P120_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR332W,MID2,KAI1,"O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p","fungal-type cell wall organization, peroxisome organization, response to chemical stimulus, response to stress, conjugation, cellular component morphogenesis, RNA metabolic process",signal transducer activity,"membrane, site of polarized growth, plasma membrane","anatomical structure morphogenesis, cell wall organization and biogenesis, membrane, plasma membrane, response to chemical stimulus, response to stress, signal transducer activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,6,2.7,no,,,,, P120,37,D1,P120_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR333C,RPS25B,rp45;YS23;S31B;S25B,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,4,1.7,no,,,,, P120,38,D2,P120_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR335W,NUP2,,"Nucleoporin involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization","transport, transcription, ribosome biogenesis, nucleus organization, RNA metabolic process",structural molecule activity,"nucleus, endomembrane system, chromosome, mitochondrion, membrane, cytoplasm","RNA metabolic process, chromosome, endomembrane system, membrane, mitochondrion, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, structural molecule activity, transcription, transport",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,34,14.3,no,,,,, P120,39,D3,P120_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR300W,,HUF1,"Dubious open reading frame, unlikely to encode a protein; overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection, though phenotype could be due to the mutation's effects on BUD7","cytokinesis, cell cycle",molecular_function,cellular_component,"anatomical structure morphogenesis, cellular_component, cytokinesis, molecular_function, other",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,24,8.6,no,,,,, P120,40,D4,P120_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR038C,CCS1,LYS7;CCS,"Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation",transport,other,"nucleus, membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, other, transport",,,13_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,13,5.9,no,,,,, P120,41,D5,P120_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR341W,SPO77,,"Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,other,"cell wall organization and biogenesis, molecular_function, other, sporulation",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,2,1.1,no,,,,, P120,42,D6,P120_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR342W,FKS1,PBR1;GSC1;ETG1;CWH53;CND1,"Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling","transport, cellular carbohydrate metabolic process, vesicle-mediated transport, cellular membrane organization",transferase activity,"cell cortex, membrane fraction, cytoskeleton, mitochondrion, membrane, cytoplasm, plasma membrane","carbohydrate metabolic process, cell cortex, cell wall organization and biogenesis, cytoplasm, cytoskeleton, membrane, membrane fraction, membrane organization and biogenesis, mitochondrion, other, plasma membrane, transferase activity, transport, vesicle-mediated transport",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,4,1.8,no,,,,, P120,43,D7,P120_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR390W-A,CCW14,ICWP;YLR391W;SSR1;YLR391W-A,"Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall",fungal-type cell wall organization,structural molecule activity,"cell wall, mitochondrion, cytoplasm","cell wall, cell wall organization and biogenesis, mitochondrion, structural molecule activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,28,11,no,,,,, P120,44,D8,P120_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR392C,ART10,,Protein of unknown function that contains 2 PY motifs and is ubiquinated by Rsp5p; green fluorescent protein (GFP)-fusion protein localizes it to the cytoplasm; non-essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,10,5.4,no,,,,, P120,45,D9,P120_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR393W,ATP10,,"Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, interacts genetically with ATP6","mitochondrion organization, protein complex biogenesis",protein binding,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, protein binding",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,10,5,no,,,,, P120,46,D10,P120_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR395C,COX8,,"Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,2,0.9,no,,,,, P120,47,D11,P120_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR364W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR365C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,24,10.2,no,,,,, P120,48,D12,P120_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR398C,SKI2,,"Ski complex component and putative RNA helicase, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay",RNA metabolic process,"helicase activity, hydrolase activity",cytoplasm,"RNA metabolic process, cytoplasm, helicase activity, nucleolus, response to chemical stimulus, translation",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,2,0.8,no,,,,, P120,49,E1,P120_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR006C,SSK1,,"Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate","response to stress, signaling process, response to chemical stimulus","signal transducer activity, enzyme regulator activity",cytoplasm,"cytoplasm, enzyme regulator activity, response to chemical stimulus, response to stress, signal transducer activity, signal transduction, transcription regulator activity",,,12_1,,,"consortium notes: QC FAILED--growth -Lys, no mate w/ A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,,160,16,10,no,,,,, P120,50,E2,P120_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR400W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,2,0.9,no,,,,, P120,51,E3,P120_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR401C,DUS3,,"Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region",RNA metabolic process,oxidoreductase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, oxidoreductase activity, ribosome biogenesis",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,30,12.9,no,,,,, P120,52,E4,P120_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR402W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,368,34,9.2,no,,,,, P120,53,E5,P120_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR403W,SFP1,,"Transcription factor that controls expression of ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, modulates cell size; regulated by TORC1 and Mrs6p","ribosome biogenesis, transcription, RNA metabolic process",DNA binding,"nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, nucleus, other, ribosome biogenesis, transcription, transcription regulator activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,20,10.8,no,,,,, P120,54,E6,P120_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR404W,FLD1,seipin;SEI1,"Seipin protein involved in lipid droplet morphology, number, and size; proposed to be involved in lipid metabolism; related to the human BSCL2 which is associated with lipodystrophy",other,molecular_function,"membrane, cell cortex, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, molecular_function, organelle organization and biogenesis",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,4,1.3,no,,,,, P120,55,E7,P120_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR405W,DUS4,,"Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p",RNA metabolic process,oxidoreductase activity,cellular_component,"RNA metabolic process, cellular_component, oxidoreductase activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,30,10.3,no,,,,, P120,56,E8,P120_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR407W,,,Putative protein of unknown function; null mutant displays elongated buds and a large fraction of budded cells have only one nucleus,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,22,7.1,no,,,,, P120,57,E9,P120_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR408C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome; YLR408C is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,46,14.6,no,,,,, P120,58,E10,P120_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR410W,VIP1,,"Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of IP7 by Vip1p is important for phosphate signaling; likely involved in cortical actin cytoskeleton function, by analogy with S. pombe ortholog asp1",cellular carbohydrate metabolic process,transferase activity,cytoplasm,"cytoplasm, other, transferase activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,4,1.8,no,,,,, P120,59,E11,P120_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR412W,BER1,,"Protein involved in microtubule-related processes, N-acetylation; GFP-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YLR412W is not an essential gene; similar to Arabidopsis SRR1 gene",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,2,1.2,no,,,,, P120,60,E12,P120_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR413W,,,Putative protein of unknown function; YLR413W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,2,0.7,no,,,,, P120,61,F1,P120_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR414C,PUN1,,Putative protein of unknown function; localizes to bud and cytoplasm; co-localizes with Sur7p in punctate patches in the plasma membrane; null mutant displays decreased thermotolerance; transcription induced on cell wall damage,biological_process,molecular_function,"cellular bud, membrane, plasma membrane, cytoplasm","biological_process, cellular bud, cytoplasm, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,4,1.9,no,,,,, P120,62,F2,P120_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR415C,,,Putative protein of unknown function; YLR415C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,166,20,12,no,,,,, P120,63,F3,P120_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR416C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,20,11.3,no,,,,, P120,64,F4,P120_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR417W,VPS36,VPL11;VAC3;GRD12,Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome,"transport, transcription, response to chemical stimulus, cellular protein catabolic process, RNA metabolic process",protein binding,"membrane, cytoplasm","RNA metabolic process, cytoplasm, membrane, other, protein catabolic process, response to chemical stimulus, signal transducer activity, transcription, transport",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,22,11.2,no,,,,, P120,65,F5,P120_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR418C,CDC73,,"Component of the Paf1p complex that binds to and modulates the activity of RNA polymerases I and II; required for expression of certain genes, modification of some histones, and telomere maintenance","chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transcription regulator activity, transposition",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,30,16.7,no,,,,, P120,66,F6,P120_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR421C,RPN13,,Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome; null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability,cellular protein catabolic process,protein binding,cytoplasm,"cytoplasm, hydrolase activity, other, peptidase activity, protein binding",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,8,3.9,no,,,,, P120,67,F7,P120_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR147W,EKI1,,"Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway","cellular lipid metabolic process, cellular amino acid and derivative metabolic process",transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, lipid metabolic process, transferase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,9,4.1,no,,,,, P120,68,F8,P120_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR148C,KGD2,,"Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated","cofactor metabolic process, mitochondrion organization, generation of precursor metabolites and energy, cellular respiration",transferase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, other, transferase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,191,18,9.4,no,,,,, P120,69,F9,P120_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR149C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps the verified gene NUM1; null mutation blocks anaerobic growth",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,6,1.9,no,,,,, P120,70,F10,P120_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR150W,NUM1,PAC12,"Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex","transport, mitochondrion organization, cytoskeleton organization",protein binding,"cell cortex, mitochondrion, cellular bud, site of polarized growth, cytoplasm","cell cortex, cellular bud, cytoskeleton organization and biogenesis, mitochondrion, organelle organization and biogenesis, protein binding, site of polarized growth, transport",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,8,5,no,,,,, P120,71,F11,P120_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR151C,CTH1,,"Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis","cellular homeostasis, RNA metabolic process",RNA binding,nucleus,"RNA binding, RNA metabolic process, cellular homeostasis, nucleus",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,48,16.6,no,,,,, P120,72,F12,P120_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR152W,GIR2,,Highly-acidic cytoplasmic RWD domain-containing protein of unknown function; interacts with Rbg1p and Gcn1p; associates with translating ribosomes; putative intrinsically unstructured protein,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,4,2,no,,,,, P120,73,G1,P120_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR153C,ENT5,,"Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin","transport, vesicle-mediated transport","protein binding, lipid binding","membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, protein binding, transport, vesicle-mediated transport",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,12,6.2,no,,,,, P120,74,G2,P120_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR154C,,,"Dubious open reading frame, null mutant exhibits synthetic phenotype with alpha-synuclein",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,28,10.4,no,,,,, P120,75,G3,P120_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR155C,CPR1,CPH1;CYP1,"Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A","protein modification process, meiosis, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle",isomerase activity,"nucleus, chromosome, mitochondrion, cytoplasm","isomerase activity, mitochondrion, nucleus, other, sporulation",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,20,10,no,,,,, P120,76,G4,P120_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR156W,RPA14,A14,RNA polymerase I subunit A14,"transcription, RNA metabolic process",molecular_function,"nucleus, nucleolus","RNA metabolic process, nucleolus, nucleotidyltransferase activity, nucleus, other, transcription, transferase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,2,0.8,no,,,,, P120,77,G5,P120_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR157W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,0,0,no,,,,, P120,78,G6,P120_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR158W,HOM2,,"Aspartic beta semi-aldehyde dehydrogenase, catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis",cellular amino acid and derivative metabolic process,oxidoreductase activity,"nucleus, membrane fraction, cytoplasm","amino acid and derivative metabolic process, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,180,1,0.6,no,,,,, P120,79,G7,P120_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR159W,SAC3,LEP1,"Nuclear pore-associated protein, required for biogenesis of the small ribosomal subunit; forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus","transport, response to stress, ribosome biogenesis, cell cycle, DNA metabolic process, RNA metabolic process",protein binding,"nucleus, endomembrane system, membrane","DNA metabolic process, RNA metabolic process, cell cycle, cytoskeleton organization and biogenesis, endomembrane system, membrane, nucleus, organelle organization and biogenesis, protein binding, response to stress, transport",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,22,10.8,no,,,,, P120,80,G8,P120_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR161W,,,Putative protein of unknown function; non-essential gene; proposed function in rRNA and ribosome biosynthesis based on transcriptional co-regulation; genetic interactions suggest a role in ER-associated protein degradation (ERAD),cellular protein catabolic process,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, ribosome biogenesis",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,16,7.5,no,,,,, P120,81,G9,P120_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR162C,NBP2,,"Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p",response to stress,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, other, response to stress",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,8,3.8,no,,,,, P120,82,G10,P120_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR163W,CWC15,,"Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has similarity to S. pombe Cwf15p",RNA metabolic process,molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,8,2.4,no,,,,, P120,83,G11,P120_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR165W,TRM82,,Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA,RNA metabolic process,"transferase activity, protein binding",nucleus,"RNA metabolic process, nucleus, protein binding, ribosome biogenesis, transferase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,6,1.9,no,,,,, P120,84,G12,P120_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR169C,STB3,,"Ribosomal RNA processing element (RRPE)-binding protein involved in the glucose-induced transition from quiescence to growth; restricted to nucleus in quiescent cells, released into cytoplasm after glucose repletion; binds Sin3p","transcription, response to chemical stimulus, RNA metabolic process",DNA binding,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,10,5.9,no,,,,, P120,85,H1,P120_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR171W,HSP42,,Small heat shock protein (sHSP) with chaperone activity; forms barrel-shaped oligomers that suppress unfolded protein aggregation; involved in cytoskeleton reorganization after heat shock,cytoskeleton organization,protein binding,"cytoskeleton, cytoplasm","cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, protein binding, response to stress",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,32,14.8,no,,,,, P120,86,H2,P120_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR176W,NGG1,SWI7;ADA3,"Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex","chromosome organization, protein modification process","transcription regulator activity, transferase activity, protein binding",nucleus,"nucleus, organelle organization and biogenesis, protein binding, protein modification process, response to chemical stimulus, transcription regulator activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,20,11.4,no,,,,, P120,87,H3,P120_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P120,88,H4,P120_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR178W,SDH4,ACN18,"Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,8,4.8,no,,,,, P120,89,H5,P120_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR179C,CSN9,,"Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling","conjugation, response to chemical stimulus, protein modification process",molecular_function,nucleus,"conjugation, molecular_function, nucleus, protein modification process, response to chemical stimulus, signal transduction",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,16,5.2,no,,,,, P120,90,H6,P120_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR179W-A,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,22,9.9,no,,,,, P120,91,H7,P120_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR181C,SAS4,,"Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p","transcription, RNA metabolic process",transferase activity,"nucleus, chromosome","RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, transcription, transferase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,15,6.7,no,,,,, P120,92,H8,P120_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR183W,PLP1,,"Protein that interacts with CCT (chaperonin containing TCP-1) complex and has a role in actin and tubulin folding; has weak similarity to phosducins, which are G-protein regulators","protein folding, transcription, response to chemical stimulus, RNA metabolic process",protein binding,cellular_component,"RNA metabolic process, cytoplasm, protein binding, protein folding, response to chemical stimulus, transcription",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,18,6.2,no,,,,, P120,93,H9,P120_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR184C,ATC1,LIC4,"Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern","response to stress, cell budding, cytokinesis, cell cycle",molecular_function,nucleus,"anatomical structure morphogenesis, cell budding, cytokinesis, molecular_function, nucleus, response to stress, ribosome biogenesis",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,14,5.1,no,,,,, P120,94,H10,P120_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR185C,UPS3,GEP2,Mitochondrial protein of unknown function; similar to Ups1p and Ups2p which are involved in regulation of mitochondrial cardiolipin and phosphatidylethanolamine levels; null is viable but interacts synthetically with ups1 and ups2 mutations,"mitochondrion organization, cellular component morphogenesis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,10,3.4,no,,,,, P120,95,H11,P120_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR186C,,,"Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,25,13.4,no,,,,, P120,96,H12,P120_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR191W,HST4,,"Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism","transcription, protein modification process, cellular lipid metabolic process, chromosome organization, RNA metabolic process","hydrolase activity, DNA binding","nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, hydrolase activity, lipid metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,8,4,no,,,,, P121,1,A1,P121_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR192C,NUP42,UIP1;RIP1,"Subunit of the nuclear pore complex (NPC) that localizes exclusively to the cytoplasmic side; involved in RNA export, most likely at a terminal step; interacts with Gle1p","transport, ribosome biogenesis, nucleus organization",structural molecule activity,"nucleus, membrane, endomembrane system","endomembrane system, membrane, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, structural molecule activity, transport",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,16,6.7,no,,,,, P121,2,A2,P121_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR193W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,3,1.4,no,,,,, P121,3,A3,P121_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR195W,REF2,,"RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes","transcription, RNA metabolic process","RNA binding, DNA binding",nucleus,"DNA binding, RNA binding, RNA metabolic process, nucleus, transcription",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,6,3.2,no,,,,, P121,4,A4,P121_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR198C,RKM2,,"Ribosomal protein lysine methyltransferase, responsible for trimethylation of the lysine residue at position 3 of Rpl12Ap and Rpl12Bp",protein modification process,transferase activity,cellular_component,"cellular_component, protein modification process, transferase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,4,2.2,no,,,,, P121,5,A5,P121_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR199W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene VPS64; computationally predicted to have thiol-disulfide oxidoreductase activity",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,5,2.6,no,,,,, P121,6,A6,P121_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR200C,VPS64,FAR9,Protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p and Far7p to Far11p involved in recovery from pheromone-induced cell cycle arrest; localizes to the cytoplasm and endoplasmic reticulum membrane,"transport, response to chemical stimulus, conjugation, cell cycle",molecular_function,"endomembrane system, membrane, endoplasmic reticulum, cytoplasm","cell cycle, conjugation, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, response to chemical stimulus, transport",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,4,1.2,no,,,,, P121,7,A7,P121_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR203W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,6,2.3,no,,,,, P121,8,A8,P121_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR204W,COQ4,,"Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex",cofactor metabolic process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,22,7.1,no,,,,, P121,9,A9,P121_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR206W,EBS1,,Protein involved in inhibition of translation and nonsense-mediated decay; interacts with cap binding protein Cdc33p and with Nam7p; localizes to P-bodies upon glucose starvation; mRNA abundance regulated by mRNA decay factors,"translation, RNA metabolic process",molecular_function,cytoplasm,"DNA metabolic process, RNA metabolic process, cytoplasm, molecular_function, organelle organization and biogenesis, translation",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,8,4,no,,,,, P121,10,A10,P121_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR207C,UME6,RIM16;NIM2;CAR80,"Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p","transcription, protein modification process, meiosis, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process","transcription regulator activity, hydrolase activity, DNA binding","nucleus, chromosome","DNA binding, DNA metabolic process, RNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, protein modification process, response to chemical stimulus, sporulation, transcription, transcription regulator activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,251,17,6.8,no,,,,, P121,11,A11,P121_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR209C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized gene YDR210W.",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,16,7.3,no,,,,, P121,12,A12,P121_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR210W,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,0,0,no,,,,, P121,13,B1,P121_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR213W,UPC2,MOX4,"Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion",other,transcription regulator activity,"nucleus, membrane, cytoplasm","cytoplasm, lipid metabolic process, nucleus, transcription regulator activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,10,3.1,no,,,,, P121,14,B2,P121_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR214W,AHA1,,Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to Hch1p; expression is regulated by stresses such as heat shock,"response to stress, protein folding","protein binding, enzyme regulator activity",cytoplasm,"cytoplasm, enzyme regulator activity, other, protein binding, protein folding, response to stress",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,5,2.8,no,,,,, P121,15,B3,P121_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR215C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,20,9.8,no,,,,, P121,16,B4,P121_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR216W,ADR1,,"Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization","transcription, peroxisome organization, response to chemical stimulus, RNA metabolic process",DNA binding,nucleus,"DNA binding, RNA metabolic process, carbohydrate metabolic process, nucleus, organelle organization and biogenesis, response to chemical stimulus, transcription, transcription regulator activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,11,6.1,no,,,,, P121,17,B5,P121_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR217C,RAD9,,"DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate","signaling process, transcription, response to stress, cell cycle, DNA metabolic process, RNA metabolic process","DNA binding, protein binding","nucleus, chromosome","DNA metabolic process, RNA metabolic process, cell cycle, chromosome, nucleus, protein binding, response to stress, signal transduction, transcription",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,18,5.4,no,,,,, P121,18,B6,P121_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR218C,SPR28,,Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation,"fungal-type cell wall organization, cellular component morphogenesis",structural molecule activity,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell cortex, cell wall organization and biogenesis, cellular bud, cytoplasm, cytoskeleton, site of polarized growth, structural molecule activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,20,6,no,,,,, P121,19,B7,P121_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR219C,MFB1,,Mitochondria-associated F-box protein involved in maintenance of normal mitochondrial morphology; interacts with Skp1p through the F-box motif; preferentially localizes to the mother cell during budding,"mitochondrion organization, cellular protein catabolic process",protein binding,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, protein binding, protein catabolic process",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,4,2.2,no,,,,, P121,20,B8,P121_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR220C,,,"Dubious open reading frame, null mutant exhibits synthetic phenotype with alpha-synuclein",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,4,2.2,no,,,,, P121,21,B9,P121_B9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P121,22,B10,P121_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR221W,GTB1,,"Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER","cellular carbohydrate metabolic process, protein modification process",hydrolase activity,"endoplasmic reticulum, cytoplasm","carbohydrate metabolic process, cytoplasm, endoplasmic reticulum, hydrolase activity, protein modification process",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,11,6.5,no,,,,, P121,23,B11,P121_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR222W,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,17,7.5,no,,,,, P121,24,B12,P121_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR223W,CRF1,,Transcriptional corepressor involved in repression of ribosomal protein (RP) gene transcription via the TOR signaling pathway which promotes accumulation of Crf1p in the nucleus; role in repression of RP genes varies by strain,"transcription, RNA metabolic process","transcription regulator activity, protein binding","nucleus, chromosome, cytoplasm","cytoplasm, nucleus, transcription, transcription regulator activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,32,9.7,no,,,,, P121,25,C1,P121_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR225W,HTA1,SPT11;H2A1,"Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p","response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, response to stress, transcription",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,36,10.7,no,,,,, P121,26,C2,P121_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR226W,ADK1,AKY2;AKY1,"Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence",heterocycle metabolic process,transferase activity,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, mitochondrial envelope, mitochondrion, other, transferase activity",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,10,5.8,no,,,,, P121,27,C3,P121_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR229W,IVY1,,"Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the action of Vps33p and vice versa, localizes to the rim of the vacuole as cells approach stationary phase","vacuole organization, cellular membrane organization",lipid binding,"membrane, vacuole, cytoplasm","cytoplasm, lipid binding, membrane, membrane organization and biogenesis, organelle organization and biogenesis, vacuole",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,18,6.6,no,,,,, P121,28,C4,P121_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR231C,COX20,,"Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase","mitochondrion organization, generation of precursor metabolites and energy, protein complex biogenesis, cellular respiration",protein binding,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, protein binding, protein modification process",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,15,7.2,no,,,,, P121,29,C5,P121_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR233C,RTN1,,"ER membrane protein that interacts with Sey1p to maintain ER morphology; interacts with exocyst subunit Sec6p, with Yip3p, and with Sbh1p; null mutant has an altered ER morphology; member of the RTNLA (reticulon-like A) subfamily",transport,molecular_function,"membrane, cell cortex, endomembrane system, mitochondrion, endoplasmic reticulum, cytoplasm, Golgi apparatus","Golgi apparatus, biological_process, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, mitochondrion, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,8,3.8,no,,,,, P121,30,C6,P121_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR234W,LYS4,LYS3,"Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway",cellular amino acid and derivative metabolic process,lyase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, lyase activity, mitochondrion",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,22,7.4,no,,,,, P121,31,C7,P121_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR237W,MRPL7,YmL7;YmL5,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,26,9,no,,,,, P121,32,C8,P121_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR239C,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,6,1.8,no,,,,, P121,33,C9,P121_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR241W,BUD26,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 1% of ORF overlaps the verified gene SNU56; diploid mutant displays a weak budding pattern phenotype in a systematic assay","cytokinesis, cell cycle",molecular_function,cellular_component,"anatomical structure morphogenesis, cellular_component, cytokinesis, molecular_function",,,04_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,20,6.5,no,,,,, P121,34,C10,P121_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR027C,AAT2,ASP5,"Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells",cellular amino acid and derivative metabolic process,transferase activity,"peroxisome, cytoplasm","amino acid and derivative metabolic process, cytoplasm, peroxisome, transferase activity",,,12_1,,,"consortium notes: Failed QC--n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,262,13,5,no,,,,, P121,35,C11,P121_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML001W,YPT7,VAM4;AST4,"Rab family GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7","vacuole organization, transport, vesicle-mediated transport, cellular membrane organization",hydrolase activity,"vacuole, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, hydrolase activity, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, vacuole, vesicle-mediated transport",,,13_2,,,"consortium notes: Failed QC--no mate w/ A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,,208,7,3.4,no,,,,, P121,36,C12,P121_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR266W,RSN1,,Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant cells by restoring sodium pump (Ena1p) localization to the plasma membrane,"transport, vesicle-mediated transport",molecular_function,membrane,"membrane, molecular_function, transport, vesicle-mediated transport",,,13_5,,,consortium notes: Failed QC--growth -Lys,DIC:cell structure;YFP:Rad52-YFP protein,,220,9,4.1,no,,,,, P121,37,D1,P121_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL330C,RPD3,MOF6;SDS6;SDI2;REC3,"Histone deacetylase; regulates transcription, silencing, and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members","transcription, protein modification process, response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process","transcription regulator activity, hydrolase activity, protein binding","nucleus, chromosome","DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, protein binding, protein modification process, response to stress, transcription, transcription regulator activity, transposition",,,14_1,,,"consortium notes: Failed QC--no mate w/ A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,images not available,298,0,0,no,,,,, P121,38,D2,P121_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR305W,RRG7,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YOR305W is not an essential gene,biological_process,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, response to chemical stimulus",,,15_4,,,"consortium notes: Failed QC--growth -Lys, mate w/ A, a little mate with alpha",DIC:cell structure;YFP:Rad52-YFP protein,,201,2,1,no,,,,, P121,39,D3,P121_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR369C,RPS12,S12,Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,15_4,,,"consortium notes: Failed QC--growth -Lys, no mate w/ A, mate w/ alpha",DIC:cell structure;YFP:Rad52-YFP protein,,314,8,2.5,no,,,,, P121,40,D4,P121_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR103W,STE5,NUL3;HMD3,"Pheromone-response scaffold protein that controls the mating decision; binds Ste11p, Ste7p, and Fus3p kinases, forming a MAPK cascade complex that interacts with the plasma membrane and Ste4p-Ste18p; allosteric activator of Fus3p","signaling process, transposition, response to chemical stimulus, protein modification process, conjugation","lipid binding, structural molecule activity, protein binding","nucleus, membrane, site of polarized growth, cytoplasm, plasma membrane","conjugation, cytoplasm, lipid binding, nucleus, other, plasma membrane, protein binding, response to chemical stimulus, signal transduction, site of polarized growth",,,04_4,,,"consortium notes: Failed qc--no mating a, a",DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P121,41,D5,P121_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR127W,ARO1,,"Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process","lyase activity, transferase activity, oxidoreductase activity",cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, lyase activity, oxidoreductase activity, transferase activity",,,04_4,,,"consortium notes: Failed QC-- -met,auxo ng,mating a, no mating a",DIC:cell structure;YFP:Rad52-YFP protein,,178,10,5.6,no,,,,, P121,42,D6,P121_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL004W,YEA4,,Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter required for cell wall chitin synthesis; localized to the ER,"transport, cellular carbohydrate metabolic process",transporter activity,"endoplasmic reticulum, cytoplasm","carbohydrate metabolic process, cell wall organization and biogenesis, endoplasmic reticulum, transport, transporter activity",,,05_2,,,"rg notes: FAILED QC-appears mat a; consortium notes: Failed qc-- growth-lys, ng -met, ng aux ,no mating a, mates w/ a",DIC:cell structure;YFP:Rad52-YFP protein,images not available,219,3,1.4,no,,,,, P121,43,D7,P121_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL029C,BUD16,,"Putative pyridoxal kinase, a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK)","cofactor metabolic process, cytokinesis, cell cycle, vitamin metabolic process, heterocycle metabolic process",transferase activity,cytoplasm,"anatomical structure morphogenesis, cellular_component, cytokinesis, transferase activity, vitamin metabolic process",,,05_2,,,"consortium notes: Failed qc-- growth-lys, ng -met, ng aux ,no mating a, mates w/ a",DIC:cell structure;YFP:Rad52-YFP protein,images not available,189,2,1.1,no,,,,, P121,44,D8,P121_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER032W,FIR1,PIP1,"Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate",RNA metabolic process,molecular_function,"cellular bud, site of polarized growth","RNA metabolic process, cellular bud, molecular_function, site of polarized growth",,,05_3,,,"consortium notes: Failed QC- no reason given,see database",DIC:cell structure;YFP:Rad52-YFP protein,,270,26,9.6,no,,,,, P121,45,D9,P121_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER039C,HVG1,YEM9,"Protein of unknown function, has homology to Vrg4p",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_3,,,"consortium notes: Failed qc--no mating a, mates w/ a",DIC:cell structure;YFP:Rad52-YFP protein,images not available,253,13,5.1,no,,,,, P121,46,D10,P121_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER052C,HOM3,SIL4;BOR1,Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis,cellular amino acid and derivative metabolic process,transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, response to chemical stimulus, transferase activity",,,05_3,,,"consortium notes: Failed QC--ng-met,ng aux",DIC:cell structure;YFP:Rad52-YFP protein,,306,14,4.6,no,,,,, P121,47,D11,P121_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER057C,HMF1,HIG1,"Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,05_3,,,"rg notes: FAILED QC-appears mat a; consortium notes: Failed QC--grow -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,332,6,1.8,no,,,,, P121,48,D12,P121_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER060W-A,FCY22,,"Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function",transport,transporter activity,membrane,"biological_process, membrane, transporter activity",,,05_3,,,rg notes: FAILED QC-appears mat a,DIC:cell structure;YFP:Rad52-YFP protein,,271,20,7.4,no,,,,, P121,49,E1,P121_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER061C,CEM1,,Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration,cellular lipid metabolic process,transferase activity,"mitochondrion, cytoplasm","lipid metabolic process, mitochondrion, transferase activity",,,05_3,,,rg notes: FAILED QC-appears mat a; consortium notes: Failed QC--grow -Lys,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,22,10.8,no,,,,, P121,50,E2,P121_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER066C-A,,,"Dubious open reading frame unlikely to encode a protein, partially overlaps uncharacterized ORF YER067W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,05_3,,,rg notes: FAILED QC-appears mat a,DIC:cell structure;YFP:Rad52-YFP protein,images not available,263,26,9.9,no,,,,, P121,51,E3,P121_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER079W,,,Putative protein of unknown function,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,05_3,,,rg notes: FAILED QC-appears mat a,DIC:cell structure;YFP:Rad52-YFP protein,images not available,212,11,5.2,no,,,,, P121,52,E4,P121_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL042W,,,"Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,08_1,,,rg notes: R21-R30 FAILED QC-DIPLOID; consortium notes: Failed QC,DIC:cell structure;YFP:Rad52-YFP protein,images not available,216,5,2.3,no,,,,, P121,53,E5,P121_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL041W,,,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,08_1,,,rg notes: R21-R30 FAILED QC-DIPLOID,DIC:cell structure;YFP:Rad52-YFP protein,,264,0,0,no,,,,, P121,54,E6,P121_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL030W,ECM29,,"Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome",other,protein binding,"nucleus, cytoplasm","cytoplasm, nucleus, other, protein binding, protein catabolic process",,,08_1,,,"rg notes: FAILED QC-APPEARS MAT A; consortium notes: Failed QC--grow -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,239,8,3.3,no,,,,, P121,55,E7,P121_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL029C,OCA5,,"Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts",biological_process,molecular_function,cytoplasm,"cytoplasm, molecular_function, other",,,08_1,,,rg notes: FAILED Q.C DIPLOID; consortium notes: Failed QC,DIC:cell structure;YFP:Rad52-YFP protein,,294,14,4.8,no,,,,, P121,56,E8,P121_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL021C,AIM17,FMP12,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,08_1,,,consortium notes: Failed QC--see database,DIC:cell structure;YFP:Rad52-YFP protein,,190,3,1.6,no,,,,, P121,57,E9,P121_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL016C,DUR3,,"Plasma membrane transporter for both urea and polyamines, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway",transport,transporter activity,"membrane, plasma membrane","other, plasma membrane, transport, transporter activity",,,08_1,,,rg notes: appears mat a,DIC:cell structure;YFP:Rad52-YFP protein,images not available,255,1,0.4,no,,,,, P121,58,E10,P121_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL007C,STE20,,"Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p","vacuole organization, response to chemical stimulus, protein modification process, conjugation, cell cycle, transport, signaling process, cytokinesis, response to stress, pseudohyphal growth","protein kinase activity, signal transducer activity, transferase activity","nucleus, membrane fraction, site of polarized growth","anatomical structure morphogenesis, cell cycle, conjugation, cytokinesis, other, protein kinase activity, protein modification process, pseudohyphal growth, response to chemical stimulus, response to stress, signal transducer activity, signal transduction, site of polarized growth, transferase activity",,,08_1,,,"consortium notes: Failed QC--no mating w/ A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,,197,4,2,no,,,,, P121,59,E11,P121_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL005C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YHL004W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,08_1,,,"rg notes: FAILED QC-APPEARS MAT A; consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,images not available,210,30,14.3,no,,,,, P121,60,E12,P121_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL003C,LAG1,,"Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p",cellular lipid metabolic process,transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, other, transferase activity",,,08_1,,,"rg notes: FAILED QC-APPEARS MAT A; consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,212,3,1.4,no,,,,, P121,61,F1,P121_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR001W-A,QCR10,,"Subunit of the ubiqunol-cytochrome c oxidoreductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and comprises part of the mitochondrial respiratory chain","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,08_1,,,"rg notes: FAILED QC-APPEARS MAT A; consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,1,0.6,no,,,,, P121,62,F2,P121_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR150W,PEX28,,"Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p",peroxisome organization,molecular_function,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, molecular_function, organelle organization and biogenesis, peroxisome",,,08_3,,,rg notes: FAILED QC-APPEARS MAT A,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,7,3.3,no,,,,, P121,63,F3,P121_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR176W,FMO1,,"Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins",protein folding,oxidoreductase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, oxidoreductase activity, protein folding",,,08_3,,,"consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux, no mate w/ A, mate w/ alpha",DIC:cell structure;YFP:Rad52-YFP protein,,260,10,3.8,no,,,,, P121,64,F4,P121_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR177W,,GON3,Putative protein of unknown function; overexpression causes a cell cycle delay or arrest,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,08_3,,,rg notes: FAILED QC-APPEARS MAT A,DIC:cell structure;YFP:Rad52-YFP protein,images not available,195,2,1,no,,,,, P121,65,F5,P121_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL032W,STE50,,"Protein involved in mating response, invasive/filamentous growth, and osmotolerance, acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction","response to stress, signaling process, conjugation, response to chemical stimulus","protein binding, enzyme regulator activity",cytoplasm,"conjugation, cytoplasm, enzyme regulator activity, protein binding, response to chemical stimulus, response to stress, signal transduction",,,03_1,,,"consortium notes: Failed qc--no mating a, a",DIC:cell structure;YFP:Rad52-YFP protein,,174,16,9.2,no,,,,, P121,66,F6,P121_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR002C,CDC10,,"Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM","response to chemical stimulus, sporulation resulting in formation of a cellular spore, conjugation, cell cycle, fungal-type cell wall organization, cell budding, cytokinesis, cellular component morphogenesis","hydrolase activity, lipid binding, structural molecule activity","cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cell wall organization and biogenesis, cellular bud, conjugation, cytokinesis, cytoplasm, cytoskeleton, hydrolase activity, lipid binding, response to chemical stimulus, site of polarized growth, sporulation, structural molecule activity",,,03_1,,,"consortium notes: Failed qc--no mating a, mates w/ a",DIC:cell structure;YFP:Rad52-YFP protein,images not available,231,3,1.3,no,,,,, P121,67,F7,P121_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL068W,NUP100,NSP100,Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup116p,"transport, ribosome biogenesis, nucleus organization",structural molecule activity,"nucleus, membrane, endomembrane system","endomembrane system, membrane, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, structural molecule activity, transport",,,11_1,,,consortium notes: Failed QC--growth -Lys,DIC:cell structure;YFP:Rad52-YFP protein,,238,21,8.8,no,,,,, P121,68,F8,P121_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL135C,APL2,,"Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting","transport, vesicle-mediated transport",protein binding,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, protein binding, transport, vesicle-mediated transport",,,11_2,,,"rg notes: FAILED QC-APPEARS MAT A; consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux, no mate w/ A, mate w/ alpha",DIC:cell structure;YFP:Rad52-YFP protein,,206,1,0.5,no,,,,, P121,69,F9,P121_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL177W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene STE3",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,"consortium notes: Failed QC--no mate w/ A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,5,2.7,no,,,,, P121,70,F10,P121_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL178C,STE3,DAF2,"Receptor for a factor pheromone, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPC","signaling process, conjugation, response to chemical stimulus",signal transducer activity,"membrane, plasma membrane","conjugation, membrane, plasma membrane, response to chemical stimulus, signal transducer activity, signal transduction",,,11_2,,,"consortium notes: Failed QC--no mate w/ A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P121,71,F11,P121_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR212W,STE4,HMD2,"G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats","signaling process, heterocycle metabolic process, transposition, response to chemical stimulus, conjugation",signal transducer activity,"membrane, plasma membrane","conjugation, membrane, other, plasma membrane, response to chemical stimulus, signal transducer activity, signal transduction",,,15_3,,,"consortium notes: Failed QC--no mate w/ A, alpha",DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P121,72,F12,P121_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL206C,,,"Putative protein of unknown function; similar to transcriptional regulators from the Zn[2]-Cys[6] binuclear cluster protein family; mRNA is weakly cell cycle regulated, peaking in S phase; induced rapidly upon MMS treatment",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_1,,,consortium notes: Failed QC--growth -Lys,DIC:cell structure;YFP:Rad52-YFP protein,,188,20,10.6,no,,,,, P121,73,G1,P121_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL204C,RCY1,,F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth,"transport, vesicle-mediated transport, cellular membrane organization",protein binding,"site of polarized growth, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, membrane organization and biogenesis, protein binding, site of polarized growth, transport, vesicle-mediated transport",,,10_1,,,consortium notes: Failed QC--growth -Lys,DIC:cell structure;YFP:Rad52-YFP protein,,256,2,0.8,no,,,,, P121,74,G2,P121_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL201W,ECM25,,Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p,fungal-type cell wall organization,molecular_function,cytoplasm,"cell wall organization and biogenesis, cytoplasm, molecular_function, other, response to chemical stimulus",,,10_1,,,"consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,179,1,0.6,no,,,,, P121,75,G3,P121_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL184W,GON7,PCC2;LDB6,"Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p","chromosome organization, transcription, DNA metabolic process, RNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, RNA metabolic process, cell wall organization and biogenesis, chromosome, nucleus, organelle organization and biogenesis, other, response to stress, transcription",,,10_1,,,"consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,272,22,8.1,no,,,,, P121,76,G4,P121_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL138C,TIF2,eIF4A,"Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G",translation,"RNA binding, helicase activity, hydrolase activity","membrane fraction, ribosome, cytoplasm","cytoplasm, helicase activity, ribosome, translation, translation regulator activity",,,10_1,,,"consortium notes: Failed QC--n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,209,27,12.9,no,,,,, P121,77,G5,P121_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL130C,URA2,,"Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process","transferase activity, ligase activity","mitochondrion, membrane, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, ligase activity, membrane, mitochondrion, transferase activity",,,10_1,,,"consortium notes: Failed QC--growth -Lys, n/g -Met, n/g Aux",DIC:cell structure;YFP:Rad52-YFP protein,,330,2,0.6,no,,,,, P121,78,G6,P121_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR173C,ARG82,ARGRIII;IPK2;ARGR3,"Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes","transcription, cellular amino acid and derivative metabolic process, cellular carbohydrate metabolic process, cellular lipid metabolic process, RNA metabolic process","transferase activity, protein binding",nucleus,"DNA metabolic process, RNA metabolic process, amino acid and derivative metabolic process, lipid metabolic process, nucleus, other, protein binding, response to chemical stimulus, transcription, transferase activity, transposition",,,04_5,,,"consortium notes: Failed qc--no mating a, a",DIC:cell structure;YFP:Rad52-YFP protein,images not available,168,10,6,no,,,,, P121,79,G7,P121_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR227W,SIR4,UTH2;STE9;ASD1,"Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan","transcription, response to stress, chromosome organization, DNA metabolic process, RNA metabolic process","DNA binding, structural molecule activity, protein binding","nucleus, chromosome","DNA metabolic process, RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, protein binding, response to stress, structural molecule activity, transcription",,,04_5,,,"consortium notes: Failed qc--no mating a, a",DIC:cell structure;YFP:Rad52-YFP protein,,ND,ND,,no,,,,, P121,80,G8,P121_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL030C,HIS4,,"Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis","cellular amino acid and derivative metabolic process, heterocycle metabolic process","hydrolase activity, oxidoreductase activity",other,"amino acid and derivative metabolic process, hydrolase activity, other, oxidoreductase activity",,,03_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,8,3.8,no,,,,, P121,81,G9,P121_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR228C,ECM22,,"Sterol regulatory element binding protein, regulates transcription of sterol biosynthetic genes; contains Zn[2]-Cys[6] binuclear cluster; homologous to Upc2p; relocates from intracellular membranes to perinuclear foci on sterol depletion",other,"transcription regulator activity, DNA binding","nucleus, membrane, cytoplasm","lipid metabolic process, nucleus, transcription regulator activity",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,11,5.1,no,,,,, P121,82,G10,P121_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR231C,BNA5,,"Kynureninase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p","cofactor metabolic process, vitamin metabolic process",hydrolase activity,"nucleus, cytoplasm","cofactor metabolic process, cytoplasm, hydrolase activity, nucleus, vitamin metabolic process",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,0,0,no,,,,, P121,83,G11,P121_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR232W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene BNA5",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,18,6.5,no,,,,, P121,84,G12,P121_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR236C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,7,2.8,no,,,,, P121,85,H1,P121_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR238W,FAR10,,"Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p substrate","conjugation, cell cycle, response to chemical stimulus",molecular_function,"endoplasmic reticulum, cytoplasm","cell cycle, conjugation, endoplasmic reticulum, molecular_function, response to chemical stimulus",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,2,1.1,no,,,,, P121,86,H2,P121_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR241W,,,"Putative protein of unknown function, may be involved in detoxification",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,3,1.3,no,,,,, P121,87,H3,P121_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P121,88,H4,P121_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR247C,IRC20,,Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci,biological_process,molecular_function,"nucleus, mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function, nucleus",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,35,15.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P121,89,H5,P121_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR248W,RCK2,CMK3;CLK1,Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations,"response to stress, meiosis, cell cycle, response to chemical stimulus, protein modification process","transferase activity, protein kinase activity",cytoplasm,"cell cycle, cytoplasm, meiosis, protein kinase activity, protein modification process, response to stress, signal transduction, transferase activity",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,4,2.4,no,,,,, P121,90,H6,P121_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR250W,SSP120,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,biological_process,molecular_function,cytoplasm,"cytoplasm, molecular_function, transport",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,12,4.2,no,,,,, P121,91,H7,P121_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR251W,SYM1,,Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17,other,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, other",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,8,3.3,no,,,,, P121,92,H8,P121_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR252W,,,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene SYM1, a mitochondrial protein involved in ethanol metabolism",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,3,1.4,no,,,,, P121,93,H9,P121_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR253W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; transcription is periodic during the metabolic cycle; YLR253W is not an essential gene",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,12,3.7,no,,,,, P121,94,H10,P121_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR254C,NDL1,,"Homolog of nuclear distribution factor NudE, NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends",transport,protein binding,"nucleus, cytoskeleton, cytoplasm","cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, nucleus, organelle organization and biogenesis, protein binding, transport",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,6,1.8,no,,,,, P121,95,H11,P121_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR255C,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,8,2.4,no,,,,, P121,96,H12,P121_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR257W,,,Putative protein of unknown function,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,189,24,12.7,no,,,,, P123,1,A1,P123_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL256W,ADH4,ZRG5;NRC465,"Alcohol dehydrogenase isoenzyme type IV, dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency","cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, generation of precursor metabolites and energy, mitochondrion, oxidoreductase activity",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,10,4.1,no,,,,, P123,2,A2,P123_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL257C,MNT2,,Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans,"cellular carbohydrate metabolic process, protein modification process",transferase activity,cellular_component,"cellular_component, protein modification process, transferase activity",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,5,2.9,no,,,,, P123,3,A3,P123_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL258W,VEL1,,Protein of unknown function; highly induced in zinc-depleted conditions and has increased expression in NAP1 deletion mutants,biological_process,molecular_function,other,"biological_process, molecular_function, other",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,16,6.3,no,,,,, P123,4,A4,P123_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL259W,YPS5,,Protein with similarity to GPI-anchored aspartic proteases such as Yap1p and Yap3p,biological_process,"peptidase activity, hydrolase activity",cellular_component,"biological_process, cellular_component, hydrolase activity, peptidase activity",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,6,2.1,no,,,,, P123,5,A5,P123_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL260W,,,Putative protein of unknown function; transcription is significantly increased in a NAP1 deletion background; deletion mutant has increased accumulation of nickel and selenium,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,8,2.6,no,,,,, P123,6,A6,P123_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL261C,PAU11,,Putative protein of unknown function and member of the seripauperin multigene family encoded mainly in subtelomeric regions; mRNA expression appears to be regulated by SUT1 and UPC2,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,4,2.4,no,,,,, P123,7,A7,P123_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL262W,,,Putative protein of unknown function; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein; YGL262W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,14,4.4,no,,,,, P123,8,A8,P123_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL263W,COS12,,"Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,12,5.1,no,,,,, P123,9,A9,P123_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR001C,,,Putative protein of unknown function with similarity to methyltransferase family members; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in S. cerevisiae,biological_process,transferase activity,cytoplasm,"biological_process, cytoplasm, transferase activity",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,12,4.6,no,,,,, P123,10,A10,P123_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR003W,CUL3,CULLIN B;CULB,"Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21","protein modification process, cellular protein catabolic process","protein binding, ligase activity","nucleus, cytoplasm","cytoplasm, ligase activity, nucleus, other, protein binding, protein catabolic process, protein modification process",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,2,1,no,,,,, P123,11,A11,P123_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR004W,PEX31,,"Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p",peroxisome organization,molecular_function,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, molecular_function, organelle organization and biogenesis, peroxisome",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,4,2.2,no,,,,, P123,12,A12,P123_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR006W,PRP18,,"Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, part of snRNP U5, interacts with Slu7p",RNA metabolic process,other,nucleus,"RNA metabolic process, nucleus, other",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,241,6,2.5,no,,,,, P123,13,B1,P123_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR007W,MUQ1,ECT1,"Choline phosphate cytidylyltransferase, catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases","cellular lipid metabolic process, cellular amino acid and derivative metabolic process","transferase activity, nucleotidyltransferase activity","nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, lipid metabolic process, nucleotidyltransferase activity, nucleus, transferase activity",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,1,0.5,no,,,,, P123,14,B2,P123_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR008C,STF2,,Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p may act as stabilizing factors that enhance inhibitory action of the Inh1p protein,heterocycle metabolic process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, other, response to stress",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,4,1.2,no,,,,, P123,15,B3,P123_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR010W,NMA2,,"Nicotinic acid mononucleotide adenylyltransferase, involved in de novo and salvage synthesis of NAD(+)",cofactor metabolic process,"transferase activity, nucleotidyltransferase activity",nucleus,"cofactor metabolic process, nucleotidyltransferase activity, nucleus, transferase activity, vitamin metabolic process",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,6,2.4,no,,,,, P123,16,B4,P123_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR012W,,,"Putative cysteine synthase, localized to the mitochondrial outer membrane",cellular amino acid and derivative metabolic process,lyase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, lyase activity, membrane, mitochondrial envelope, mitochondrion",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,8,4.1,no,,,,, P123,17,B5,P123_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR014W,MSB2,,Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate,"response to stress, signaling process",signal transducer activity,"membrane, site of polarized growth, plasma membrane","anatomical structure morphogenesis, membrane, plasma membrane, response to stress, signal transducer activity, signal transduction, site of polarized growth",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,8,3.8,no,,,,, P123,18,B6,P123_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR015C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,8,3.2,no,,,,, P123,19,B7,P123_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR016W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,6,3.1,no,,,,, P123,20,B8,P123_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR017W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,8,2.9,no,,,,, P123,21,B9,P123_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR019W,UGA1,,Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization,cellular amino acid and derivative metabolic process,transferase activity,other,"amino acid and derivative metabolic process, aromatic compound metabolic process, lipid metabolic process, other, transferase activity",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,4,2,no,,,,, P123,22,B10,P123_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR020C,VMA7,,"Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,2,0.6,no,,,,, P123,23,B11,P123_B11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P123,24,B12,P123_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR021W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,4,1.4,no,,,,, P123,25,C1,P123_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR023W,MTL1,,"Putative plasma membrane sensor, involved in cell integrity signaling and stress response during glucose starvation and oxidative stress; has structural and functional similarity to Mid2p","response to stress, fungal-type cell wall organization, response to chemical stimulus",molecular_function,"membrane, plasma membrane","cell wall organization and biogenesis, membrane, molecular_function, plasma membrane",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,10,5.7,no,,,,, P123,26,C2,P123_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR026W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,5,2.6,no,,,,, P123,27,C3,P123_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL091W,GLR1,LPG17,"Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione; mitochondrial but not cytosolic form has a role in resistance to hyperoxia","response to stress, response to chemical stimulus, protein modification process",oxidoreductase activity,"nucleus, mitochondrion, cytoplasm","cytoplasm, mitochondrion, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,42,13.4,no,,,,, P123,28,C4,P123_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL090C,RPS6A,rp9;YS4;S6A;S10A,Protein component of the small (40S) ribosomal subunit; identical to Rps6Bp and has similarity to rat S6 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,146,20,13.7,no,,,,, P123,29,C5,P123_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL089C,RLM1,,"MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p","fungal-type cell wall organization, signaling process, transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding, protein binding",nucleus,"DNA binding, RNA metabolic process, cell wall organization and biogenesis, nucleus, protein binding, response to chemical stimulus, signal transduction, transcription, transcription regulator activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,4,1.6,no,,,,, P123,30,C6,P123_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL088W,,,Putative aryl alcohol dehydrogenase; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance,other,oxidoreductase activity,cellular_component,"cellular_component, other, oxidoreductase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,6,3.4,no,,,,, P123,31,C7,P123_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL087W,YDC1,,"Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity",cellular lipid metabolic process,hydrolase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, lipid metabolic process, response to stress",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,16,8.6,no,,,,, P123,32,C8,P123_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL086C,ELP3,KAT9;KTI8;TOT3;HPA1,"Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin","transcription, RNA metabolic process",transferase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, other, transcription, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P123,33,C9,P123_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL084W,BRO1,NPI3;ASI6;VPS31;LPF2,Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes,"transport, response to chemical stimulus, protein modification process, vesicle-mediated transport, cellular protein catabolic process","peptidase activity, hydrolase activity","membrane fraction, cytoplasm","cytoplasm, hydrolase activity, membrane fraction, peptidase activity, protein catabolic process, protein modification process, response to chemical stimulus, transport, vesicle-mediated transport",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,0,0,no,,,,, P123,34,C10,P123_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL081W,RPS9A,rp21;YS11;S9A;S13,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins,"translation, ribosome biogenesis, RNA metabolic process","RNA binding, structural molecule activity","ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,150,22,14.7,no,,,,, P123,35,C11,P123_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL080C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,12,3.8,no,,,,, P123,36,C12,P123_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL079W,RPL21B,L21B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Ap and has similarity to rat L21 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,216,9,4.2,no,,,,, P123,37,D1,P123_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL078C,ATP4,LPF7,"Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated","transport, heterocycle metabolic process","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,38,11.4,no,,,,, P123,38,D2,P123_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL077C,,,Putative protein of unknown function; regulates PIS1 expression; mutant displays spore wall assembly defect in ether sensitivity screen; YPL077C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,10,3.4,no,,,,, P123,39,D3,P123_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL074W,YTA6,,"Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells",biological_process,hydrolase activity,"cell cortex, cytoplasm","biological_process, cell cortex, hydrolase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,28,14.1,no,,,,, P123,40,D4,P123_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL073C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps with verified gene UBP16/YPL072W; may interact with ribosome based on co-purification experiments",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,0,0,no,,,,, P123,41,D5,P123_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL072W,UBP16,,"Deubiquitinating enzyme anchored to the outer mitochondrial membrane, probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria",protein modification process,"peptidase activity, hydrolase activity","membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, peptidase activity, protein modification process",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,26,10.3,no,,,,, P123,42,D6,P123_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL071C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,24,8.5,no,,,,, P123,43,D7,P123_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL070W,MUK1,,Cytoplasmic protein of unknown function containing a Vps9 domain; computational analysis of large-scale protein-protein interaction data suggests a possible role in transcriptional regulation,biological_process,molecular_function,cytoplasm,"cytoplasm, molecular_function, transcription",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,24,7.1,no,,,,, P123,44,D8,P123_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL069C,BTS1,,"Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic",cellular lipid metabolic process,transferase activity,"mitochondrion, cytoplasm","lipid metabolic process, mitochondrion, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,148,26,17.6,no,,,,, P123,45,D9,P123_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL068C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and is induced in response to the DNA-damaging agent MMS,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,14,6.9,no,,,,, P123,46,D10,P123_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL067C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL067C is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,30,11.5,no,,,,, P123,47,D11,P123_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL066W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the bud neck and cytoplasm; null mutant is viable and exhibits growth defect on a non-fermentable (respiratory) carbon source,biological_process,molecular_function,"cellular bud, site of polarized growth, cytoplasm","biological_process, cellular bud, cytoplasm, molecular_function, site of polarized growth",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,20,8.7,no,,,,, P123,48,D12,P123_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL065W,VPS28,VPL13;VPT28,"Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, and Mvb12p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p","transport, cellular protein catabolic process",protein binding,"membrane, cytoplasm","cytoplasm, membrane, protein binding, protein catabolic process, transport",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,20,6.1,no,,,,, P123,49,E1,P123_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL064C,CWC27,,"Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p",biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,34,12.8,no,,,,, P123,50,E2,P123_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL062W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,13,7.3,no,,,,, P123,51,E3,P123_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL061W,ALD6,ALD1,"Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress","response to stress, cofactor metabolic process",oxidoreductase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,166,24,14.5,no,,,,, P123,52,E4,P123_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL060W,,LPE10,"Mitochondrial inner membrane magnesium transporter, involved in maintenance of magnesium concentrations inside mitochondria; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,24,7.1,no,,,,, P123,53,E5,P123_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL059W,GRX5,,Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p,"response to stress, cofactor metabolic process, response to chemical stimulus",oxidoreductase activity,"mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, mitochondrion, oxidoreductase activity, response to chemical stimulus, response to stress",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P123,54,E6,P123_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL058C,PDR12,,"Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity",transport,"transporter activity, hydrolase activity","membrane, plasma membrane","hydrolase activity, other, plasma membrane, transport, transporter activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,32,18.2,no,,,,, P123,55,E7,P123_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL057C,SUR1,LPE15;CSG1;BCL21,"Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p",cellular lipid metabolic process,transferase activity,other,"lipid metabolic process, other, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,24,13.6,no,,,,, P123,56,E8,P123_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL056C,LCL1,,Putative protein of unknown function; deletion mutant is fluconazole resistant and has long chronological lifespan,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,8,3.4,no,,,,, P123,57,E9,P123_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL055C,LGE1,,"Protein of unknown function; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division","chromosome organization, DNA metabolic process, protein modification process",molecular_function,nucleus,"DNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, other, protein modification process",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,263,12,4.6,no,,,,, P123,58,E10,P123_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL054W,LEE1,,Zinc-finger protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,12,5.8,no,,,,, P123,59,E11,P123_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL053C,KTR6,MNN6,Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family,"fungal-type cell wall organization, cellular carbohydrate metabolic process, protein modification process",transferase activity,membrane fraction,"cell wall organization and biogenesis, membrane fraction, protein modification process, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,150,28,18.7,no,,,,, P123,60,E12,P123_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL052W,OAZ1,YPL052W-A,"Regulator of ornithine decarboxylase (Spe1p), antizyme that binds to Spe1p to regulate ubiquitin-independent degradation; ribosomal frameshifting during synthesis of Oaz1p and its ubiquitin-mediated degradation are both polyamine-regulated",other,enzyme regulator activity,other,"enzyme regulator activity, other, protein catabolic process",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,16,6,no,,,,, P123,61,F1,P123_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL051W,ARL3,,GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor,"transport, vesicle-mediated transport",hydrolase activity,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, endomembrane system, hydrolase activity, membrane, other, transport, vesicle-mediated transport",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,10,5.8,no,,,,, P123,62,F2,P123_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL050C,MNN9,,"Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation","cellular carbohydrate metabolic process, cytokinesis, protein modification process",transferase activity,"membrane, cytoplasm, Golgi apparatus","Golgi apparatus, cytokinesis, cytoplasm, membrane, protein modification process, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,28,10.1,no,,,,, P123,63,F3,P123_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL049C,DIG1,RST1,"Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription",other,"DNA binding, protein binding",nucleus,"DNA binding, nucleus, other, protein binding",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,26,9.6,no,,,,, P123,64,F4,P123_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL048W,CAM1,CPBP;TEF3,Nuclear protein required for transcription of MXR1; binds the MXR1 promoter in the presence of other nuclear factors; binds calcium and phospholipids; has similarity to translational cofactor EF-1 gamma,"ribosome biogenesis, transcription, RNA metabolic process","transcription regulator activity, protein binding, lipid binding",nucleus,"RNA metabolic process, lipid binding, nucleus, other, protein binding, ribosome biogenesis, transcription, transcription regulator activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,146,12,8.2,no,,,,, P123,65,F5,P123_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL047W,SGF11,,"Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation","chromosome organization, transcription, protein modification process, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, protein modification process, transcription",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,4,1.5,no,,,,, P123,66,F6,P123_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL046C,ELC1,,"Elongin C, involved in transcription elongation as a heterodimer with Ela1p; required for ubiquitin-dependent degradation of Rpo21p; plays a role in global genomic nucleotide excision repair; expression highly upregulated during sporulation","transcription, protein modification process, response to stress, chromosome organization, DNA metabolic process, RNA metabolic process, cellular protein catabolic process","transcription regulator activity, ligase activity",nucleus,"DNA metabolic process, RNA metabolic process, ligase activity, nucleus, organelle organization and biogenesis, other, protein catabolic process, protein modification process, response to stress, transcription, transcription regulator activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,16,5.9,no,,,,, P123,67,F7,P123_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL045W,VPS16,VPT16;VAM9;SVL6,Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stages,"vacuole organization, transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular membrane organization",lipid binding,"vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vacuole, vesicle-mediated transport",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,16,9.1,no,,,,, P123,68,F8,P123_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL042C,SSN3,CDK8;RYE5;UME5;SRB10;NUT7;GIG2,"Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression","transcription, protein modification process, meiosis, cell cycle, RNA metabolic process","transcription regulator activity, transferase activity, protein kinase activity",nucleus,"RNA metabolic process, meiosis, nucleus, protein kinase activity, protein modification process, transcription, transcription regulator activity, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,265,0,0,no,,,,, P123,69,F9,P123_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL041C,,,Protein of unknown function involved in maintenance of proper telomere length,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,30,16.3,no,,,,, P123,70,F10,P123_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL040C,ISM1,mitochondrial isoleucyl-tRNA synthetase,"Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth","mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,210,14,6.7,no,,,,, P123,71,F11,P123_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL039W,,,Putative protein of unknown function; YPL039W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,16,8.5,no,,,,, P123,72,F12,P123_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL038W,MET31,,"Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p","transcription, cellular amino acid and derivative metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","DNA binding, amino acid and derivative metabolic process, cytoplasm, nucleus, transcription, transcription regulator activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,10,3.5,no,,,,, P123,73,G1,P123_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL037C,EGD1,,"Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b",protein folding,protein binding,cytoplasm,"cytoplasm, protein binding, protein folding, ribosome",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,14,5.8,no,,,,, P123,74,G2,P123_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL035C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YPL034W; YPL035C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,7,3.8,no,,,,, P123,75,G3,P123_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL033C,SRL4,,Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p,other,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,6,3.2,no,,,,, P123,76,G4,P123_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL032C,SVL3,,"Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck","transport, vesicle-mediated transport, cellular membrane organization",molecular_function,"cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoplasm, membrane organization and biogenesis, molecular_function, site of polarized growth, transport, vesicle-mediated transport",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,18,6.7,no,,,,, P123,77,G5,P123_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL031C,PHO85,phoU;LDB15,"Cyclin-dependent kinase, with ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle","fungal-type cell wall organization, signaling process, transcription, generation of precursor metabolites and energy, protein modification process, response to stress, cellular carbohydrate metabolic process, cell cycle, RNA metabolic process","transferase activity, protein kinase activity",nucleus,"RNA metabolic process, anatomical structure morphogenesis, carbohydrate metabolic process, cell cycle, cell wall organization and biogenesis, generation of precursor metabolites and energy, nucleus, other, protein kinase activity, protein modification process, response to chemical stimulus, response to stress, signal transduction, transcription, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,185,14,7.6,no,,,,, P123,78,G6,P123_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL030W,TRM44,,tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential gene,RNA metabolic process,transferase activity,cytoplasm,"RNA metabolic process, cytoplasm, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,20,7.1,no,,,,, P123,79,G7,P123_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL029W,SUV3,LPB2,"ATP-dependent RNA helicase, component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates RNA turnover; also required during splicing of the COX1 AI5_beta intron",RNA metabolic process,"helicase activity, hydrolase activity","mitochondrion, cytoplasm","RNA metabolic process, cytoplasm, helicase activity, hydrolase activity, mitochondrion",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,174,4,2.3,no,,,,, P123,80,G8,P123_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL026C,SKS1,SHA3,Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway,"transport, transcription, response to chemical stimulus, protein modification process, RNA metabolic process","transferase activity, protein kinase activity","nucleus, cytoplasm","RNA metabolic process, cytoplasm, protein kinase activity, protein modification process, response to chemical stimulus, transcription, transferase activity, transport",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,22,9.7,no,,,,, P123,81,G9,P123_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL025C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,6,2.1,no,,,,, P123,82,G10,P123_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL024W,RMI1,NCE4,Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing and ssDNA binding activities of Top3p; involved in response to DNA damage; null mutants display increased rates of recombination and delayed S phase,"chromosome segregation, response to stress, chromosome organization, cell cycle","enzyme regulator activity, DNA binding","nucleus, chromosome, cytoplasm","DNA binding, chromosome, cytoplasm, nucleus, response to stress",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,204,80,39.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P123,83,G11,P123_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL023C,MET12,,Protein with methylenetetrahydrofolate reductase (MTHFR) activity in vitro; null mutant has no phenotype and is prototrophic for methionine; MET13 encodes major isozyme of MTHFR,biological_process,oxidoreductase activity,cellular_component,"biological_process, cellular_component, oxidoreductase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,20,6.7,no,,,,, P123,84,G12,P123_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL022W,RAD1,LPB9,"Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein","response to stress, meiosis, cell cycle, DNA metabolic process","DNA binding, hydrolase activity",nucleus,"DNA binding, DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, response to stress",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,6,2.6,no,,,,, P123,85,H1,P123_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL021W,ECM23,SRD2,"Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p",pseudohyphal growth,DNA binding,cellular_component,"cellular_component, molecular_function, pseudohyphal growth",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,26,8.6,no,,,,, P123,86,H2,P123_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL019C,VTC3,PHM2,"Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion","vacuole organization, transport, cellular membrane organization",molecular_function,"vacuole, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vacuole",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,26,7.9,no,,,,, P123,87,H3,P123_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P123,88,H4,P123_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL018W,CTF19,MCM18,"Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly","cytoskeleton organization, chromosome organization, cell cycle, chromosome segregation",protein binding,"nucleus, chromosome","chromosome, cytoskeleton organization and biogenesis, nucleus, organelle organization and biogenesis, other, protein binding",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,146,54,37,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P123,89,H5,P123_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL017C,IRC15,,"Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci","cytoskeleton organization, chromosome segregation, meiosis, chromosome organization, cell cycle, DNA metabolic process","transferase activity, protein binding","cytoskeleton, cytoplasm","DNA metabolic process, cell cycle, cytoplasm, meiosis, organelle organization and biogenesis, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,56,27.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P123,90,H6,P123_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL015C,HST2,,Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro,"transcription, DNA metabolic process, RNA metabolic process",hydrolase activity,cytoplasm,"DNA metabolic process, RNA metabolic process, cytoplasm, hydrolase activity, organelle organization and biogenesis, other, transcription",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,24,7.1,no,,,,, P123,91,H7,P123_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL014W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,14,4.7,no,,,,, P123,92,H8,P123_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL013C,MRPS16,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,258,60,23.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P123,93,H9,P123_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL009C,,,"Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL009C is not an essential gene",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,4,2,no,,,,, P123,94,H10,P123_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL008W,CHL1,MCM12;LPA9;CTF1,"Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p","chromosome organization, cell cycle, DNA metabolic process, chromosome segregation","helicase activity, hydrolase activity",nucleus,"DNA metabolic process, cell cycle, helicase activity, nucleus, organelle organization and biogenesis, other",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,12,6.1,no,,,,, P123,95,H11,P123_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL006W,NCR1,,"Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein",cellular lipid metabolic process,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, lipid metabolic process, membrane, transporter activity, vacuole",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,189,7,3.7,no,,,,, P123,96,H12,P123_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL005W,AEP3,,"Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex",RNA metabolic process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","RNA metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,0,0,no,,,,, P124,1,A1,P124_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL003W,ULA1,ENR2,"Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation",protein modification process,other,cellular_component,"cellular_component, other, protein modification process",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,12,4.4,no,,,,, P124,2,A2,P124_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL002C,SNF8,VPL14;VPS22,"Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; appears to be functionally related to SNF7; involved in glucose derepression","transport, transcription, response to chemical stimulus, cellular protein catabolic process, RNA metabolic process",protein binding,"membrane, cytoplasm","RNA metabolic process, cytoplasm, membrane, protein binding, protein catabolic process, response to chemical stimulus, transcription, transport",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,8,2.8,no,,,,, P124,3,A3,P124_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL001W,HAT1,KAT1,"Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair","chromosome organization, transcription, protein modification process, RNA metabolic process","transferase activity, protein binding","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,146,12,8.2,no,,,,, P124,4,A4,P124_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR001W,CIT3,,Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate,"cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",transferase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, generation of precursor metabolites and energy, mitochondrion, other, transferase activity",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,2,0.8,no,,,,, P124,5,A5,P124_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR002W,PDH1,,"Mitochondrial protein that participates in respiration, induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate",other,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, other",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,6,2.6,no,,,,, P124,6,A6,P124_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR003C,,,Putative sulfate permease; physically interacts with Hsp82p; green fluorescent protein (GFP)-fusion protein localizes to the ER; YPR003C is not an essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,6,3.5,no,,,,, P124,7,A7,P124_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR004C,AIM45,,"Protein with similarity to mammalian electron transfer flavoprotein complex subunit ETF-alpha; interacts with frataxin, Yfh1p; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,6,2.4,no,,,,, P124,8,A8,P124_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR005C,HAL1,,"Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p","response to stress, transcription, RNA metabolic process",molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, response to stress, transcription",,,16_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,3,1.7,no,,,,, P124,9,A9,P124_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR106W,ISR1,,"Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C",biological_process,"transferase activity, protein kinase activity",cellular_component,"biological_process, cellular_component, protein kinase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,20,10,no,,,,, P124,10,A10,P124_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR109W,,,Predicted membrane protein; dipoid deletion strain has high budding index,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,10,4.7,no,,,,, P124,11,A11,P124_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR111W,DBF20,,"Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis","cell cycle, protein modification process","transferase activity, protein kinase activity",cytoplasm,"cell cycle, cytoplasm, protein kinase activity, protein modification process, transferase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,22,8.1,no,,,,, P124,12,A12,P124_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR114W,,,Putative protein of unknown function,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,12,5.2,no,,,,, P124,13,B1,P124_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR115W,RGC1,GCA1,Pleckstrin homology domain containing protein proposed to function as a glycerol channel activator; paralogous to Ask10p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,transport,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,148,4,2.7,no,,,,, P124,14,B2,P124_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR116W,RRG8,,"Putative protein of unknown function, required for mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport",mitochondrion organization,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,6,3,no,,,,, P124,15,B3,P124_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR117W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,4,1.6,no,,,,, P124,16,B4,P124_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR119W,CLB2,,"B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome","cytoskeleton organization, cell cycle",enzyme regulator activity,"nucleus, cytoskeleton, microtubule organizing center, cellular bud, site of polarized growth, cytoplasm","cell cycle, cellular bud, cytoplasm, cytoskeleton, enzyme regulator activity, microtubule organizing center, nucleus, site of polarized growth",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,14,5,no,,,,, P124,17,B5,P124_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR120C,CLB5,,B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase,"cytoskeleton organization, cell cycle, DNA metabolic process",enzyme regulator activity,nucleus,"DNA metabolic process, cell cycle, cytoskeleton organization and biogenesis, enzyme regulator activity, nucleus, organelle organization and biogenesis",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,28,13.7,no,,,,, P124,18,B6,P124_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR121W,THI22,,Protein with similarity to hydroxymethylpyrimidine phosphate kinases; member of a gene family with THI20 and THI21; not required for thiamine biosynthesis,"vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cellular_component,"cellular_component, transferase activity, vitamin metabolic process",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,13,6.5,no,,,,, P124,19,B7,P124_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR122W,AXL1,STE22;FUS5,Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone; required for axial budding pattern of haploid cells,"cell budding, cytokinesis, cell cycle","peptidase activity, hydrolase activity","cellular bud, site of polarized growth, membrane fraction","anatomical structure morphogenesis, cell budding, cellular bud, conjugation, cytokinesis, hydrolase activity, membrane, peptidase activity, protein modification process, site of polarized growth",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,4,1.8,no,,,,, P124,20,B8,P124_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR123C,,,Hypothetical protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,239,17,7.1,no,,,,, P124,21,B9,P124_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR124W,CTR1,,"High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels",transport,transporter activity,"membrane, membrane fraction, plasma membrane","membrane fraction, plasma membrane, transport, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,273,26,9.5,no,,,,, P124,22,B10,P124_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR125W,YLH47,MRS7,"Mitochondrial inner membrane protein exposed to the mitochondrial matrix, associates with mitochondrial ribosomes, NOT required for respiratory growth; homolog of human Letm1, a protein implicated in Wolf-Hirschhorn syndrome","transport, mitochondrion organization, cellular membrane organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,6,3.3,no,,,,, P124,23,B11,P124_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR126C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,232,17,7.3,no,,,,, P124,24,B12,P124_B12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P124,25,C1,P124_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR127W,,,"Protein of unknown function, differentially expressed during alcoholic fermentation; expression activated by transcription factor YRM1/YOR172W; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,14,6.3,no,,,,, P124,26,C2,P124_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR128C,ANT1,,Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation,"transport, cellular lipid metabolic process, peroxisome organization",transporter activity,"peroxisome, membrane, cytoplasm","cytoplasm, lipid metabolic process, membrane, organelle organization and biogenesis, peroxisome, transport, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,238,8,3.4,no,,,,, P124,27,C3,P124_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR129W,SCD6,LSM13,Protein containing an Lsm domain; negatively regulates translation initiation via 48S preinitiation complex assembly; may bind RNA and have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1,"translation, RNA metabolic process",RNA binding,cytoplasm,"RNA binding, RNA metabolic process, cytoplasm",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,14,5.6,no,,,,, P124,28,C4,P124_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR130C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,7,3.8,no,,,,, P124,29,C5,P124_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR131C,NAT3,NAA20,"Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met","mitochondrion organization, cytoskeleton organization, protein modification process",transferase activity,cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein modification process, transferase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,187,9,4.8,no,,,,, P124,30,C6,P124_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR132W,RPS23B,rp37;YS14;S28B;S23B,"Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Ap and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal","translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,6,2.3,no,,,,, P124,31,C7,P124_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR134W,MSS18,,Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions,RNA metabolic process,molecular_function,"mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,4,1.7,no,,,,, P124,32,C8,P124_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR135W,CTF4,POB1;CHL15,"Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion","response to stress, chromosome organization, cell cycle, DNA metabolic process, chromosome segregation",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, nucleus, organelle organization and biogenesis, other, response to stress",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,71,41.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P124,33,C9,P124_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR138C,MEP3,,Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease,transport,transporter activity,"membrane, plasma membrane","other, plasma membrane, transport, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,12,4.4,no,,,,, P124,34,C10,P124_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR139C,VPS66,,Cytoplasmic protein of unknown function involved in vacuolar protein sorting.,transport,molecular_function,cytoplasm,"cytoplasm, molecular_function, transport",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,308,6,1.9,no,,,,, P124,35,C11,P124_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR140W,TAZ1,,"Lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; may remodel acyl groups of cardiolipin in the inner membrane; human ortholog tafazzin is implicated in Barth syndrome","mitochondrion organization, generation of precursor metabolites and energy, protein complex biogenesis, cellular respiration, cellular lipid metabolic process, cellular membrane organization",transferase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, generation of precursor metabolites and energy, lipid metabolic process, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, transferase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,20,6.1,no,,,,, P124,36,C12,P124_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR141C,KAR3,OSR11,"Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate","transport, chromosome segregation, meiosis, conjugation, chromosome organization, cell cycle, nucleus organization","motor activity, hydrolase activity, protein binding","cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, conjugation, cytoplasm, cytoskeleton, meiosis, microtubule organizing center, motor activity, nuclear organization and biogenesis, organelle organization and biogenesis",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,24,9.5,no,,,,, P124,37,D1,P124_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR145W,ASN1,,"Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway",cellular amino acid and derivative metabolic process,ligase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, ligase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,152,6,3.9,no,,,,, P124,38,D2,P124_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR146C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,4,2.1,no,,,,, P124,39,D3,P124_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR147C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,0,0,no,,,,, P124,40,D4,P124_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR148C,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,6,3,no,,,,, P124,41,D5,P124_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR149W,NCE102,NCE2,Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs),"transport, protein modification process, protein complex biogenesis, cellular membrane organization",molecular_function,"membrane fraction, mitochondrion, cellular bud, membrane, endoplasmic reticulum, cytoplasm, plasma membrane","cytoplasm, endoplasmic reticulum, membrane, membrane fraction, mitochondrion, molecular_function, plasma membrane, transport",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,6,2.7,no,,,,, P124,42,D6,P124_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR150W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SUE1/YPR151C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,10,5,no,,,,, P124,43,D7,P124_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR152C,URN1,,Putative protein of unknown function containing WW and FF domains; overexpression causes accumulation of cells in G1 phase,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,6,2.6,no,,,,, P124,44,D8,P124_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR153W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,8,3.8,no,,,,, P124,45,D9,P124_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR154W,PIN3,LSB2,Protein that induces appearance of [PIN+] prion when overproduced,cytoskeleton organization,molecular_function,"nucleus, cytoplasm","cytoplasm, cytoskeleton organization and biogenesis, molecular_function, nucleus, organelle organization and biogenesis",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,20,7,no,,,,, P124,46,D10,P124_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR155C,NCA2,,Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p,"generation of precursor metabolites and energy, cellular respiration, RNA metabolic process",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","RNA metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,10,5.9,no,,,,, P124,47,D11,P124_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR156C,TPO3,,Polyamine transport protein specific for spermine; localizes to the plasma membrane; member of the major facilitator superfamily,transport,transporter activity,"membrane, membrane fraction, vacuole, plasma membrane, cytoplasm","cytoplasm, membrane, membrane fraction, plasma membrane, transport, transporter activity, vacuole",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,4,1.7,no,,,,, P124,48,D12,P124_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR157W,,,Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,2,1.3,no,,,,, P124,49,E1,P124_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR158W,CUR1,,Protein of unknown function involved in destabilization of [URE3] prions; similar in sequence to Btn2p,biological_process,molecular_function,nucleus,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,15,6,no,,,,, P124,50,E2,P124_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR159W,KRE6,CWH48,"Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functionally redundant with Skn1p","fungal-type cell wall organization, cellular carbohydrate metabolic process",hydrolase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm, Golgi apparatus","Golgi apparatus, carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, endomembrane system, endoplasmic reticulum, hydrolase activity, membrane",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,8,4.4,no,,,,, P124,51,E3,P124_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR160W,GPH1,,"Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,6,3.5,no,,,,, P124,52,E4,P124_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR163C,TIF3,STM1;RBL3,"Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA",translation,RNA binding,"ribosome, cytoplasm","RNA binding, ribosome, translation, translation regulator activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,174,3,1.7,no,,,,, P124,53,E5,P124_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR164W,MMS1,SLM6;RTT108,Subunit of an E3 ubiquitin ligase complex involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; regulates Ty1 transposition; involved with Rtt101p in nonfunctional rRNA decay,"response to stress, DNA metabolic process, transposition, RNA metabolic process",molecular_function,other,"DNA metabolic process, cellular_component, molecular_function, response to stress, transposition",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,263,92,35,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P124,54,E6,P124_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR166C,MRP2,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,8,3.6,no,,,,, P124,55,E7,P124_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR167C,MET16,,"3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism",cellular amino acid and derivative metabolic process,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, other, oxidoreductase activity, response to chemical stimulus",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,8,4.8,no,,,,, P124,56,E8,P124_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR170C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORFs YPR169W-A and YPR170W-B",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,4,2.2,no,,,,, P124,57,E9,P124_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR171W,BSP1,,Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton,other,protein binding,"cellular bud, cell cortex, site of polarized growth, membrane fraction, cytoskeleton, cytoplasm","cell cortex, cellular bud, cytoplasm, cytoskeleton, membrane fraction, other, protein binding, site of polarized growth",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,16,6.3,no,,,,, P124,58,E10,P124_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR172W,,,"Protein of unknown function, transcriptionally activated by Yrm1p along with genes involved in multidrug resistance",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,6,2.1,no,,,,, P124,59,E11,P124_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR173C,VPS4,DID6;VPT10;VPL4;GRD13;END13;CSC1,"AAA-ATPase involved in multivesicular body (MVB) protein sorting, ATP-bound Vps4p localizes to endosomes and catalyzes ESCRT-III disassembly and membrane release; ATPase activity is activated by Vta1p; regulates cellular sterol metabolism","transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular membrane organization","hydrolase activity, protein binding","membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, hydrolase activity, lipid metabolic process, membrane, other, transport, vesicle-mediated transport",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,10,4.7,no,,,,, P124,60,E12,P124_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR174C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; potential Cdc28p substrate,biological_process,molecular_function,"nucleus, cytoskeleton, microtubule organizing center, endomembrane system, cytoplasm","biological_process, cytoplasm, cytoskeleton, endomembrane system, microtubule organizing center, molecular_function, nucleus",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,1,0.6,no,,,,, P124,61,F1,P124_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR179C,HDA3,PLO1,Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that contains an Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; has similarity to Hda2p,"transcription, protein modification process, chromosome segregation, chromosome organization, RNA metabolic process","hydrolase activity, DNA binding","nucleus, chromosome","RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, other, protein modification process, transcription",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,0,0,no,,,,, P124,62,F2,P124_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR184W,GDB1,,"Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria","cellular carbohydrate metabolic process, generation of precursor metabolites and energy","transferase activity, hydrolase activity","mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, mitochondrion, transferase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,12,7,no,,,,, P124,63,F3,P124_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR185W,ATG13,APG13,"Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; involved in Atg9p, Atg23p, and Atg27p cycling","transport, response to stress, cellular membrane organization",enzyme regulator activity,"membrane, cytoplasm","cytoplasm, enzyme regulator activity, membrane, membrane organization and biogenesis, other, response to stress, transport",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,175,6,3.4,no,,,,, P124,64,F4,P124_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR188C,MLC2,,"Regulatory light chain for the type II myosin, Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring","cytokinesis, cell cycle",protein binding,"cellular bud, cell cortex, site of polarized growth, cytoskeleton, cytoplasm","cell cortex, cell cycle, cellular bud, cytokinesis, cytoplasm, cytoskeleton, protein binding, site of polarized growth",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,2,1.1,no,,,,, P124,65,F5,P124_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR189W,SKI3,SKI5,"Ski complex component and TPR protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay",RNA metabolic process,molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, response to chemical stimulus, translation",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,2,0.9,no,,,,, P124,66,F6,P124_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR191W,QCR2,UCR2;COR2,"Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,10,3.6,no,,,,, P124,67,F7,P124_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR192W,AQY1,,"Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance","transport, sporulation resulting in formation of a cellular spore",transporter activity,"membrane, plasma membrane","plasma membrane, sporulation, transport, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,4,1.7,no,,,,, P124,68,F8,P124_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR193C,HPA2,KAT10,"Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity","chromosome organization, protein modification process, protein complex biogenesis","transferase activity, protein binding",cytoplasm,"cytoplasm, organelle organization and biogenesis, protein modification process, transferase activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,54,8,14.8,no,,,,, P124,69,F9,P124_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR194C,OPT2,,"Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles","vacuole organization, transport, cellular membrane organization",transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,8,4.6,no,,,,, P124,70,F10,P124_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR195C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,28,9.6,no,,,,, P124,71,F11,P124_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR196W,,,Putative maltose activator,biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,8,4.3,no,,,,, P124,72,F12,P124_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR197C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,20,8.8,no,,,,, P124,73,G1,P124_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR198W,SGE1,NOR1,"Plasma membrane multidrug transporter of the major facilitator superfamily, acts as an extrusion permease; partial multicopy suppressor of gal11 mutations","transport, response to chemical stimulus",transporter activity,"membrane, plasma membrane","membrane, plasma membrane, response to chemical stimulus, transport, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,32,14.5,no,,,,, P124,74,G2,P124_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR199C,ARR1,ACR1;YAP8,"Transcriptional activator of the basic leucine zipper (bZIP) family, required for transcription of genes involved in resistance to arsenic compounds","transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,14,7.7,no,,,,, P124,75,G3,P124_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR200C,ARR2,ACR2,Arsenate reductase required for arsenate resistance; converts arsenate to arsenite which can then be exported from cells by Arr3p,response to chemical stimulus,oxidoreductase activity,cellular_component,"cellular_component, oxidoreductase activity, response to chemical stimulus",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,3,1.5,no,,,,, P124,76,G4,P124_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR201W,ARR3,ACR3,"Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite",transport,transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,16_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,198,8,4,no,,,,, P124,77,G5,P124_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR090C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YCR090C is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,181,15,8.3,no,,,,, P124,78,G6,P124_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR091W,KIN82,FPK2,Putative serine/threonine protein kinase implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases) Lem3p-Dnf1p/Dnf2p; similar to Fpk1p,"transport, response to chemical stimulus, protein modification process, cellular membrane organization","transferase activity, protein kinase activity",cellular_component,"cellular_component, protein kinase activity, protein modification process, response to chemical stimulus",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,187,14,7.5,no,,,,, P124,79,G7,P124_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR092C,MSH3,,"Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability","response to stress, meiosis, cell cycle, DNA metabolic process",DNA binding,"nucleus, cytoplasm","DNA binding, DNA metabolic process, cell cycle, cytoplasm, meiosis, nucleus, response to stress",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,14,6.4,no,,,,, P124,80,G8,P124_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR098C,GIT1,,"Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,17,7.7,no,,,,, P124,81,G9,P124_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR099C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,16,8.5,no,,,,, P124,82,G10,P124_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR100C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,182,6,3.3,no,,,,, P124,83,G11,P124_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR101C,,,Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene,biological_process,molecular_function,membrane fraction,"biological_process, membrane fraction, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,3,1.7,no,,,,, P124,84,G12,P124_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR102C,,,"Putative protein of unknown function, involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family",response to chemical stimulus,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,195,11,5.6,no,,,,, P124,85,H1,P124_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR105W,ADH7,ADHVII,NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance,other,oxidoreductase activity,other,"other, oxidoreductase activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,308,50,16.2,no,,,,, P124,86,H2,P124_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR106W,RDS1,,Zinc cluster transcription factor involved in conferring resistance to cycloheximide,response to chemical stimulus,"transcription regulator activity, DNA binding",nucleus,"DNA binding, nucleus, response to chemical stimulus, transcription regulator activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,17,8.4,no,,,,, P124,87,H3,P124_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P124,88,H4,P124_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL130W-A,STF1,AIS2,Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p may act as stabilizing factors that enhance inhibitory action of the Inh1p protein,heterocycle metabolic process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, other",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,182,14,7.7,no,,,,, P124,89,H5,P124_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR363W-A,SEM1,HOD1;DSS1,Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; involved in mRNA export mediated by the TREX-2 complex (Sac3p-Thp1p); ortholog of human DSS1,"transport, protein complex biogenesis, vesicle-mediated transport, cell cycle, cellular protein catabolic process",molecular_function,"nucleus, membrane fraction, cytoplasm","cell cycle, cytoplasm, membrane fraction, molecular_function, nucleus, other, protein catabolic process, transport, vesicle-mediated transport",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,222,24,10.8,no,,,,, P124,90,H6,P124_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR525W-A,SNA2,,"Protein of unknown function, has similarity to Pmp3p, which is involved in cation transport; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern",biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,240,18,7.5,no,,,,, P124,91,H7,P124_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR535C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YDR535C is not an essential gene.",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,211,0,0,no,,,,, P124,92,H8,P124_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR536W,STL1,,"Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock",transport,transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,224,12,5.4,no,,,,, P124,93,H9,P124_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR538W,PAD1,POF1,"Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives; homolog of E. coli UbiX","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",lyase activity,"mitochondrion, cytoplasm","aromatic compound metabolic process, lyase activity, mitochondrion",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,221,24,10.9,no,,,,, P124,94,H10,P124_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR539W,FDC1,,"Ferulic acid decarboxylase, essential for decarboxylation of phenylacrylic acids; homolog of E. coli UbiD; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,239,2,0.8,no,,,,, P124,95,H11,P124_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR540C,IRC4,,Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus,DNA metabolic process,molecular_function,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, molecular_function, nucleus",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,53,23.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P124,96,H12,P124_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR541C,,,Putative dihydrokaempferol 4-reductase,biological_process,oxidoreductase activity,cellular_component,"biological_process, cellular_component, oxidoreductase activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,255,11,4.3,no,,,,, P125,1,A1,P125_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER039C-A,,,Putative protein of unknown function; YER039C-A is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,154,4,2.6,no,,,,, P125,2,A2,P125_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER091C-A,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,162,10,6.2,no,,,,, P125,3,A3,P125_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER144C,UBP5,,"Putative ubiquitin-specific protease, closest paralog of Doa4p but has no functional overlap; concentrates at the bud neck",protein modification process,"peptidase activity, hydrolase activity","cellular bud, site of polarized growth","cellular bud, hydrolase activity, other, peptidase activity, protein modification process, site of polarized growth",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,12,3.8,no,,,,, P125,4,A4,P125_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER188W,,,Hypothetical protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,2,1.2,no,,,,, P125,5,A5,P125_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL034C-A,RPL22B,rp4;l1c;YL31;L22B;YFL035C-B,"Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,15,7.3,no,,,,, P125,6,A6,P125_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR032C,RRT5,,Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,7,3.2,no,,,,, P125,7,A7,P125_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR032C-A,RPL29,YL43;L29,"Protein component of the large (60S) ribosomal subunit, has similarity to rat L29 ribosomal protein; not essential for translation, but required for proper joining of the large and small ribosomal subunits and for normal translation rate",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,46,16,no,,,,, P125,8,A8,P125_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR033C,QCR6,UCR6;COR3,"Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,10,5.5,no,,,,, P125,9,A9,P125_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR034C,PHO4,phoD,Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability,"response to stress, chromosome organization, transcription, RNA metabolic process",DNA binding,"nucleus, cytoplasm","DNA binding, cytoplasm, nucleus, other, response to stress, transcription regulator activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,16,8.7,no,,,,, P125,10,A10,P125_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR035C,,,"Putative protein of unknown function, deletion mutant exhibits synthetic phenotype with alpha-synuclein",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,32,10.1,no,,,,, P125,11,A11,P125_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR036W,CDC26,SCD26;HIT3,"Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition","cytoskeleton organization, protein modification process, chromosome segregation, chromosome organization, cell cycle, cellular protein catabolic process","ligase activity, protein binding",nucleus,"cell cycle, cytoskeleton organization and biogenesis, ligase activity, nucleus, organelle organization and biogenesis, protein binding, protein catabolic process, protein modification process",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,17,9,no,,,,, P125,12,A12,P125_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR038W,IRC5,,Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci,DNA metabolic process,molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,56,21.1,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P125,13,B1,P125_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR040W,SAP155,,"Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p",cell cycle,"phosphoprotein phosphatase activity, hydrolase activity",cytoplasm,"cell cycle, cytoplasm, hydrolase activity, phosphoprotein phosphatase activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,8,4.8,no,,,,, P125,14,B2,P125_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR041C,ERJ5,,Type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response,protein folding,molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, protein folding",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,6,2.3,no,,,,, P125,15,B3,P125_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR043C,IRC6,,Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,71,36.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P125,16,B4,P125_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR044C,DUG1,,Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p),"cofactor metabolic process, cellular amino acid and derivative metabolic process","peptidase activity, hydrolase activity","ribosome, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, hydrolase activity, mitochondrion, peptidase activity, ribosome",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,22,10.7,no,,,,, P125,17,B5,P125_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR045W,,,"Putative mitochondrial transport protein; null mutant is viable, exhibits decreased levels of chitin and normal resistance to calcofluor white",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,26,8.7,no,,,,, P125,18,B6,P125_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR046C,CNN1,,"Kinetochore protein of unknown function; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1.",chromosome segregation,molecular_function,"nucleus, chromosome","chromosome, molecular_function, nucleus, other",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,28,13.3,no,,,,, P125,19,B7,P125_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR047C,BNA6,QPT1,"Quinolinate phosphoribosyl transferase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p","cofactor metabolic process, vitamin metabolic process",transferase activity,"nucleus, cytoplasm","cofactor metabolic process, cytoplasm, nucleus, transferase activity, vitamin metabolic process",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,12,4,no,,,,, P125,20,B8,P125_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR048W,RMD8,,Cytosolic protein required for sporulation,biological_process,molecular_function,cytoplasm,"cytoplasm, molecular_function, response to chemical stimulus",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,26,10.2,no,,,,, P125,21,B9,P125_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR049W,YMR31,,"Mitochondrial ribosomal protein of the small subunit, has similarity to human mitochondrial ribosomal protein MRP-S36",translation,structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,40,20.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P125,22,B10,P125_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR053C,HXK1,,"Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p","transport, cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,"mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity, transport",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,34,10.9,no,,,,, P125,23,B11,P125_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR054C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,24,13.9,no,,,,, P125,24,B12,P125_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR055W,IRC7,,"Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner","cellular homeostasis, DNA metabolic process",lyase activity,cellular_component,"DNA metabolic process, cellular homeostasis, cellular_component, lyase activity, other",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,118,34,28.8,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P125,25,C1,P125_C1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P125,26,C2,P125_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR056C,,,Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,16,6.2,no,,,,, P125,27,C3,P125_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR057W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,140,4,2.9,no,,,,, P125,28,C4,P125_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR219W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MRPL9/YGR220C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,253,22,8.7,no,,,,, P125,29,C5,P125_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR220C,MRPL9,YmL9,Mitochondrial ribosomal protein of the large subunit,translation,structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, transferase activity, translation",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,264,34,12.9,no,,,,, P125,30,C6,P125_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR221C,TOS2,,Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p,cell budding,molecular_function,"cellular bud, site of polarized growth","cell budding, cellular bud, molecular_function, site of polarized growth",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,2,0.6,no,,,,, P125,31,C7,P125_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR222W,PET54,,Mitochondrial inner membrane protein that binds to the 5' UTR of the COX3 mRNA to activate its translation together with Pet122p and Pet494p; also binds to the COX1 Group I intron AI5 beta to facilitate exon ligation during splicing,"mitochondrion organization, translation, RNA metabolic process","translation regulator activity, RNA binding","membrane, mitochondrial envelope, mitochondrion, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, translation, translation regulator activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,221,11,5,no,,,,, P125,32,C8,P125_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR223C,HSV2,,"Phosphatidylinositol 3,5-bisphosphate-binding protein, plays a role in micronucleophagy; predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization",cellular membrane organization,lipid binding,"membrane fraction, vacuole, cytoplasm","biological_process, cytoplasm, lipid binding, vacuole",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,14,6.9,no,,,,, P125,33,C9,P125_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR224W,AZR1,,"Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole","transport, response to chemical stimulus",transporter activity,"membrane, plasma membrane","plasma membrane, response to chemical stimulus, transport, transporter activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,10,3.4,no,,,,, P125,34,C10,P125_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR225W,AMA1,SPO70,Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis,"meiosis, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cell cycle",enzyme regulator activity,nucleus,"cell cycle, cell wall organization and biogenesis, enzyme regulator activity, meiosis, nucleus, protein catabolic process, sporulation",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,7,3.7,no,,,,, P125,35,C11,P125_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR226C,,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; overlaps significantly with a verified ORF, AMA1/YGR225W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,20,6.5,no,,,,, P125,36,C12,P125_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR227W,DIE2,ALG10,"Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1","cellular carbohydrate metabolic process, protein modification process",transferase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein modification process, transferase activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,4,1.3,no,,,,, P125,37,D1,P125_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR228W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SMI1/YGR229C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,8,3.1,no,,,,, P125,38,D2,P125_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR229C,SMI1,KNR4,Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity,cell cycle,molecular_function,"cellular bud, site of polarized growth","cell cycle, cell wall organization and biogenesis, cellular bud, molecular_function, other, site of polarized growth",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,8,3.3,no,,,,, P125,39,D3,P125_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR230W,BNS1,,"Protein with some similarity to Spo12p; overexpression bypasses need for Spo12p, but not required for meiosis","meiosis, cell cycle",molecular_function,cellular_component,"cellular_component, meiosis, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,0,0,no,,,,, P125,40,D4,P125_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR231C,PHB2,,"Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation","protein folding, mitochondrion organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, other, protein folding",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,12,6.4,no,,,,, P125,41,D5,P125_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR232W,NAS6,,"Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6",protein complex biogenesis,molecular_function,"nucleus, cytoplasm","molecular_function, other",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,8,2.7,no,,,,, P125,42,D6,P125_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR233C,PHO81,phoS,"Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p",other,enzyme regulator activity,"nucleus, cytoplasm","cytoplasm, enzyme regulator activity, nucleus, other",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,4,1.8,no,,,,, P125,43,D7,P125_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR234W,YHB1,YHB4,"Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses",response to stress,oxidoreductase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, oxidoreductase activity, response to stress",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,10,4,no,,,,, P125,44,D8,P125_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR235C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,6,2,no,,,,, P125,45,D9,P125_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR236C,SPG1,,"Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,367,0,0,no,,,,, P125,46,D10,P125_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR237C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,4,1.5,no,,,,, P125,47,D11,P125_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR240C,PFK1,,"Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,"mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, transferase activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,2,0.7,no,,,,, P125,48,D12,P125_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR241C,YAP1802,,"Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family","transport, vesicle-mediated transport, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, membrane organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,6,3.5,no,,,,, P125,49,E1,P125_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR242W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,283,0,0,no,,,,, P125,50,E2,P125_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR243W,FMP43,,"Putative protein of unknown function; expression regulated by osmotic and alkaline stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,232,3,1.3,no,,,,, P125,51,E3,P125_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR244C,LSC2,,"Beta subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",ligase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, generation of precursor metabolites and energy, ligase activity, mitochondrion",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,3,1.4,no,,,,, P125,52,E4,P125_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR247W,CPD1,,"Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression",other,hydrolase activity,"cytoplasmic membrane-bounded vesicle, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, hydrolase activity, other",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,267,0,0,no,,,,, P125,53,E5,P125_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR249W,MGA1,,Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants,other,DNA binding,nucleus,"DNA binding, nucleus, other, transcription regulator activity",,,00_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,2,0.9,no,,,,, P125,54,E6,P125_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL001C,ECM15,,"Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis",fungal-type cell wall organization,molecular_function,"nucleus, cytoplasm","cell wall organization and biogenesis, cytoplasm, molecular_function, nucleus",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,315,0,0,no,,,,, P125,55,E7,P125_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL002W,HTB2,,"Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB1; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation",chromosome organization,DNA binding,"nucleus, chromosome","DNA binding, chromosome, nucleus, organelle organization and biogenesis",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,4,1.4,no,,,,, P125,56,E8,P125_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL003C,HTA2,H2A2,"Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical (see also HTA1) subtypes; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p","response to stress, chromosome organization, DNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, response to stress",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,5,2.9,no,,,,, P125,57,E9,P125_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL005W,PDR3,TPE2;AMY2,"Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)","transcription, response to chemical stimulus, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,1,0.6,no,,,,, P125,58,E10,P125_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL006C,LDB7,RSC14,"Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions","chromosome organization, transcription, RNA metabolic process",hydrolase activity,nucleus,"RNA metabolic process, cell wall organization and biogenesis, hydrolase activity, nucleus, organelle organization and biogenesis, transcription",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,183,1,0.5,no,,,,, P125,59,E11,P125_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL007C,SLA1,,Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains,"transport, fungal-type cell wall organization, cell budding, cytoskeleton organization, cytokinesis, vesicle-mediated transport, cell cycle, cellular membrane organization",protein binding,"nucleus, cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cell wall organization and biogenesis, cytokinesis, cytoskeleton organization and biogenesis, membrane organization and biogenesis, nucleus, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,219,1,0.5,no,,,,, P125,60,E12,P125_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL008W,HIR1,,"Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores","chromosome organization, transcription, RNA metabolic process","transcription regulator activity, DNA binding, protein binding","nucleus, chromosome","DNA binding, RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, other, protein binding, transcription, transcription regulator activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,2,0.9,no,,,,, P125,61,F1,P125_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL009W,ALK2,,Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins,"meiosis, cell cycle, protein modification process","transferase activity, protein kinase activity",cellular_component,"cell cycle, cellular_component, meiosis, protein kinase activity, protein modification process, transferase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,3,1.5,no,,,,, P125,62,F2,P125_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL010C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein colocalizes with clathrin-coated vesicles,biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm","biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,1,0.5,no,,,,, P125,63,F3,P125_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL011W,SCT1,GAT2,"Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase of the glycerolipid biosynthesis pathway, prefers 16-carbon fatty acids, similar to Gpt2p, gene is constitutively transcribed",cellular lipid metabolic process,transferase activity,"membrane fraction, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, transferase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,2,0.6,no,,,,, P125,64,F4,P125_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL012C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,2,1,no,,,,, P125,65,F5,P125_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL013W,FMT1,methionyl-tRNA transformylase,"Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate","translation, cellular amino acid and derivative metabolic process, RNA metabolic process",transferase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, mitochondrion, transferase activity, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,257,2,0.8,no,,,,, P125,66,F6,P125_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL015W,ACH1,,"Protein with CoA transferase activity, particularly for CoASH transfer from succinyl-CoA to acetate; has minor acetyl-CoA-hydrolase activity; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth",other,"transferase activity, hydrolase activity","mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, hydrolase activity, mitochondrion, other",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,6,2.1,no,,,,, P125,67,F7,P125_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL016W,FUS3,DAC2,"Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation","signaling process, transposition, response to chemical stimulus, protein modification process, conjugation, cell cycle","transferase activity, protein kinase activity, signal transducer activity","nucleus, mitochondrion, site of polarized growth, cytoplasm","cell cycle, conjugation, cytoplasm, mitochondrion, nucleus, other, protein kinase activity, protein modification process, response to chemical stimulus, signal transducer activity, signal transduction, site of polarized growth, transferase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,10,5.1,no,,,,, P125,68,F8,P125_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL017C,PEP1,VPT1;VPS10,Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments,"transport, cellular protein catabolic process",other,"cytoplasm, Golgi apparatus","Golgi apparatus, other, protein catabolic process, transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,4,1.5,no,,,,, P125,69,F9,P125_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL019W,APN2,ETH1,Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII,"response to stress, DNA metabolic process","lyase activity, hydrolase activity",nucleus,"DNA metabolic process, hydrolase activity, lyase activity, nucleus, response to stress",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,7,3,no,,,,, P125,70,F10,P125_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL021C,HAP3,,"Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding",transcription,transcription regulator activity,nucleus,"carbohydrate metabolic process, nucleus, transcription, transcription regulator activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,221,2,0.9,no,,,,, P125,71,F11,P125_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL022C,PIM1,LON1,"ATP-dependent Lon protease, involved in degradation of misfolded proteins in mitochondria; required for biogenesis and maintenance of mitochondria","protein complex biogenesis, cellular protein catabolic process","peptidase activity, hydrolase activity","mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, other, peptidase activity, response to stress",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,8,4.3,no,,,,, P125,72,F12,P125_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL024W,NCL1,TRM4,"S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120",RNA metabolic process,transferase activity,nucleus,"RNA metabolic process, nucleus, ribosome biogenesis, transferase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,6,2.7,no,,,,, P125,73,G1,P125_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL025W,RRN10,,"Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I","transcription, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, nucleolus","DNA binding, RNA metabolic process, nucleolus, nucleus, transcription, transcription regulator activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,2,0.9,no,,,,, P125,74,G2,P125_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL027W,RPL19B,rpl5L;YL14;L23B;L19B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Ap and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,0,0,no,,,,, P125,75,G3,P125_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL028C,,,Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; predicted to be involved in ribosome biogenesis,biological_process,molecular_function,"nucleus, nucleolus, ribosome, cytoplasm","cytoplasm, molecular_function, nucleolus, nucleus, ribosome, ribosome biogenesis",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,420,2,0.5,no,,,,, P125,76,G4,P125_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL029W,,,Non-essential protein of unknown function,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,2,0.8,no,,,,, P125,77,G5,P125_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL031W,SHE1,,"Mitotic spindle protein that interacts with components of the Dam1 (DASH) complex, its effector Sli15p, and microtubule-associated protein Bim1p; also localizes to nuclear microtubules and to the bud neck in a ring-shaped structure","cytoskeleton organization, cell cycle",molecular_function,"nucleus, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","biological_process, cytoskeleton, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,191,7,3.7,no,,,,, P125,78,G6,P125_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL032W,HEK2,KHD1,"RNA binding protein involved in the asymmetric localization of ASH1 mRNA; represses translation of ASH1 mRNA, an effect reversed by Yck1p-dependent phosphoryation; regulates telomere position effect and length; similarity to hnRNP-K","chromosome organization, DNA metabolic process",RNA binding,"nucleus, chromosome, cytoplasm","DNA metabolic process, RNA binding, chromosome, cytoplasm, nucleus, organelle organization and biogenesis, other",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,241,4,1.7,no,,,,, P125,79,G7,P125_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL036C,,,Putative non-specific single-domain racemase based on structural similarity; binds pyridoxal 5'-phosphate; expression of GFP-fusion protein induced in response to the DNA-damaging agent MMS,biological_process,other,cellular_component,"amino acid and derivative metabolic process, isomerase activity, other",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,170,4,2.4,no,,,,, P125,80,G8,P125_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL037W,APL3,,"Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, plasma membrane, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, plasma membrane, vesicle-mediated transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,2,1.1,no,,,,, P125,81,G9,P125_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL038W,MRPL16,,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation","transferase activity, structural molecule activity","ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, transferase activity, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,236,6,2.5,no,,,,, P125,82,G10,P125_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL039C,URA7,,"Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis","cellular lipid metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",ligase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, ligase activity, lipid metabolic process, other",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,1,0.5,no,,,,, P125,83,G11,P125_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL042C,FUI1,,"High affinity uridine permease, localizes to the plasma membrane; also mediates low but significant transport of the cytotoxic nucleoside analog 5-fluorouridine; not involved in uracil transport",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,8,4.4,no,,,,, P125,84,G12,P125_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL043W,ECM13,,Non-essential protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation,fungal-type cell wall organization,molecular_function,cellular_component,"cell wall organization and biogenesis, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,4,1.9,no,,,,, P125,85,H1,P125_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL044W,,,Putative protein of unknown function; YBL044W is not an essential protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,8,2.6,no,,,,, P125,86,H2,P125_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL045C,COR1,QCR1,"Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,197,5,2.5,no,,,,, P125,87,H3,P125_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P125,88,H4,P125_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL046W,PSY4,,Putative regulatory subunit of an evolutionarily conserved protein phosphatase; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; required for cisplatin resistance; homolog of mammalian R2,"response to chemical stimulus, protein modification process",enzyme regulator activity,"nucleus, cytoplasm","enzyme regulator activity, nucleus, protein modification process, response to chemical stimulus",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,300,8,2.7,no,,,,, P125,89,H5,P125_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL047C,EDE1,BUD15,"Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins","transport, response to chemical stimulus, response to stress, vesicle-mediated transport, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","cell cortex, cellular bud, cytoplasm, cytoskeleton, membrane organization and biogenesis, protein binding, response to chemical stimulus, response to stress, signal transduction, site of polarized growth, transport, vesicle-mediated transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,304,8,2.6,no,,,,, P125,90,H6,P125_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL048W,RRT1,,"Identified in a screen for mutants with increased levels of rDNA transcription; dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,4,2.2,no,,,,, P125,91,H7,P125_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL049W,MOH1,,"Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for survival in stationary phase",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,2,1.1,no,,,,, P125,92,H8,P125_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL051C,PIN4,MDT1,"Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage","response to stress, signaling process, cell cycle",molecular_function,cytoplasm,"cell cycle, cytoplasm, molecular_function, response to stress, signal transduction",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,3,1.4,no,,,,, P125,93,H9,P125_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL052C,SAS3,KAT6,"Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality","chromosome organization, transcription, protein modification process, RNA metabolic process",transferase activity,nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transferase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,8,2.4,no,,,,, P125,94,H10,P125_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL053W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,223,1,0.4,no,,,,, P125,95,H11,P125_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL054W,TOD6,PBF1,"PAC motif binding protein involved in rRNA and ribosome biogenesis; subunit of the RPD3L histone deacetylase complex; Myb-like HTH transcription factor, similar to Dot6p; hypophosphorylated by rapamycin treatment in a Sch9p-dependent manne","transcription, RNA metabolic process",DNA binding,"nucleus, chromosome, cytoplasm","cytoplasm, molecular_function, nucleus, ribosome biogenesis",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,4,1.4,no,,,,, P125,96,H12,P125_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL055C,,Tat-D,3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian and C. elegans apoptotic nucleases,"response to stress, DNA metabolic process, response to chemical stimulus",hydrolase activity,cytoplasm,"DNA metabolic process, cytoplasm, hydrolase activity, nuclear organization and biogenesis, organelle organization and biogenesis, response to chemical stimulus, response to stress, signal transduction",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,2,0.8,no,,,,, P126,1,A1,P126_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL056W,PTC3,,Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation,"response to stress, signaling process, cell cycle, protein modification process","phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","cell cycle, cytoplasm, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process, response to stress, signal transduction",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,8,2.9,no,,,,, P126,2,A2,P126_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL057C,PTH2,,One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth,cellular protein catabolic process,hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, protein catabolic process, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,1,0.5,no,,,,, P126,3,A3,P126_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL058W,SHP1,UBX1,UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate,"cytoskeleton organization, generation of precursor metabolites and energy, chromosome segregation, cellular carbohydrate metabolic process, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle, cellular protein catabolic process",enzyme regulator activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, enzyme regulator activity, generation of precursor metabolites and energy, nucleus, protein catabolic process, sporulation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,5,2.6,no,,,,, P126,4,A4,P126_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL059W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,4,1.6,no,,,,, P126,5,A5,P126_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL060W,YEL1,,Guanine nucleotide exchange factor specific for Arf3p; localized to the bud neck and tip; required for localization of Arf3p to the bud neck and tip,cellular lipid metabolic process,enzyme regulator activity,"cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoplasm, enzyme regulator activity, other, site of polarized growth",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,3,1.7,no,,,,, P126,6,A6,P126_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL061C,SKT5,CSD4;CHS4;CAL2,"Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation","cytokinesis, response to stress, cellular carbohydrate metabolic process",enzyme regulator activity,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","carbohydrate metabolic process, cell cortex, cell wall organization and biogenesis, cellular bud, cytokinesis, cytoplasm, cytoskeleton, enzyme regulator activity, other, response to stress, site of polarized growth",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,1,0.5,no,,,,, P126,7,A7,P126_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL062W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,2,0.6,no,,,,, P126,8,A8,P126_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL063W,KIP1,CIN9,"Kinesin-related motor protein required for mitotic spindle assembly, chromosome segregation, and 2 micron plasmid partitioning; functionally redundant with Cin8p for chromosomal but not plasmid functions","cytoskeleton organization, chromosome segregation, chromosome organization, cell cycle","motor activity, hydrolase activity, structural molecule activity","cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, motor activity, organelle organization and biogenesis, structural molecule activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,0,0,no,,,,, P126,9,A9,P126_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL064C,PRX1,,"Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; reactivation requires Trr2p and glutathione; induced during respiratory growth and oxidative stress; phosphorylated","response to stress, cellular homeostasis, response to chemical stimulus",oxidoreductase activity,"mitochondrion, cytoplasm","cellular homeostasis, mitochondrion, oxidoreductase activity, response to chemical stimulus, response to stress",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,2,0.6,no,,,,, P126,10,A10,P126_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL065W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF SEF1/YBL066C; YBL065W is a non-essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,2,0.6,no,,,,, P126,11,A11,P126_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL066C,SEF1,,"Putative transcription factor, has homolog in Kluyveromyces lactis",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P126,12,A12,P126_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL067C,UBP13,,"Putative ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions",biological_process,"peptidase activity, hydrolase activity",cellular_component,"biological_process, cellular_component, hydrolase activity, peptidase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,8,2.7,no,,,,, P126,13,B1,P126_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL068W,PRS4,,"5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes","fungal-type cell wall organization, cellular carbohydrate metabolic process, heterocycle metabolic process",transferase activity,cytoplasm,"carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, ribosome biogenesis, transferase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,0,0,no,,,,, P126,14,B2,P126_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL069W,AST1,,"Peripheral membrane protein that interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane, possibly by influencing its incorporation into lipid rafts",transport,molecular_function,membrane,"membrane, molecular_function, transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,277,0,0,no,,,,, P126,15,B3,P126_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL070C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,331,0,0,no,,,,, P126,16,B4,P126_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL071C,,,"Dubious open reading frame, predicted protein contains a peroxisomal targeting signal",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,0,0,no,,,,, P126,17,B5,P126_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL072C,RPS8A,rp19;YS9;S8A;S14A,Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,3,1.8,no,,,,, P126,18,B6,P126_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL075C,SSA3,YG106,ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm,"transport, response to stress, protein folding","protein binding, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, protein binding, protein folding, response to stress, transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,4,2.2,no,,,,, P126,19,B7,P126_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL078C,ATG8,AUT7;CVT5;APG8,"Component of autophagosomes and Cvt vesicles; undergoes conjugation to phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation","vacuole organization, transport, response to stress, vesicle-mediated transport, cellular membrane organization",molecular_function,"vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, response to stress, transport, vacuole, vesicle-mediated transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,6,2.1,no,,,,, P126,20,B8,P126_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL079W,NUP170,NLE3,"Subunit of the nuclear pore complex (NPC), required for NPC localization of specific nucleoporins; involved in nuclear envelope permeability and chromosome segregation; has similar to Nup157p; essential role, with Nup157p, in NPC assembly","transport, protein complex biogenesis, chromosome segregation, ribosome biogenesis, nucleus organization",structural molecule activity,"nucleus, endomembrane system, membrane","endomembrane system, membrane, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, other, structural molecule activity, transport",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,2,0.9,no,,,,, P126,21,B9,P126_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL080C,PET112,,Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog,"mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","cellular respiration, generation of precursor metabolites and energy, mitochondrion, molecular_function, organelle organization and biogenesis, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,2,0.9,no,,,,, P126,22,B10,P126_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL081W,,,Non-essential protein of unknown function; null mutation results in a decrease in plasma membrane electron transport,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,6,2.3,no,,,,, P126,23,B11,P126_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL082C,ALG3,RHK1,"Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins","cellular carbohydrate metabolic process, cellular lipid metabolic process, protein modification process",transferase activity,"endoplasmic reticulum, cytoplasm","carbohydrate metabolic process, endoplasmic reticulum, lipid metabolic process, protein modification process, transferase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,2,0.7,no,,,,, P126,24,B12,P126_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL083C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,4,1.8,no,,,,, P126,25,C1,P126_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL085W,BOI1,BOB1;GIN7,"Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain","cell budding, signaling process, cytokinesis",lipid binding,"cellular bud, site of polarized growth","anatomical structure morphogenesis, cell budding, cellular bud, cytokinesis, lipid binding, signal transduction, site of polarized growth",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,1,0.6,no,,,,, P126,26,C2,P126_C2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P126,27,C3,P126_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL086C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,4,1.7,no,,,,, P126,28,C4,P126_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL087C,RPL23A,YL32;L23A;L17aA,"Protein component of the large (60S) ribosomal subunit, identical to Rpl23Bp and has similarity to E. coli L14 and rat L23 ribosomal proteins",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,8,3.1,no,,,,, P126,29,C5,P126_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL088C,TEL1,,Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene,"protein modification process, response to stress, chromosome organization, DNA metabolic process","transferase activity, protein kinase activity, DNA binding","nucleus, mitochondrion, cytoplasm","DNA binding, DNA metabolic process, mitochondrion, nucleus, organelle organization and biogenesis, other, protein kinase activity, protein modification process, response to stress",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,289,5,1.7,no,,,,, P126,30,C6,P126_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL089W,AVT5,,"Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters",transport,transporter activity,cellular_component,"cellular_component, transport, transporter activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,6,3.4,no,,,,, P126,31,C7,P126_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL090W,MRP21,MRP50,Mitochondrial ribosomal protein of the small subunit; MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,5,2.6,no,,,,, P126,32,C8,P126_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL091C,MAP2,,"Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p",protein modification process,"peptidase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, other, peptidase activity",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,4,1.5,no,,,,, P126,33,C9,P126_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL094C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YBL095W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,02_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,4,1.3,no,,,,, P126,34,C10,P126_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL002W,ERP6,,"Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","transport, vesicle-mediated transport",molecular_function,"membrane, mitochondrion, cytoplasm","membrane, mitochondrion, molecular_function, transport, vesicle-mediated transport",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,14,5.6,no,,,,, P126,35,C11,P126_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL003C,CDH1,HCT1,"Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p","cytoskeleton organization, protein modification process, chromosome segregation, chromosome organization, cell cycle, cellular protein catabolic process","ligase activity, protein binding","nucleus, cytoplasm","cell cycle, cytoplasm, cytoskeleton organization and biogenesis, ligase activity, nucleus, organelle organization and biogenesis, other, protein binding, protein catabolic process, protein modification process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,24,9.6,no,,,,, P126,36,C12,P126_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL004C,RPN14,,Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p,"protein complex biogenesis, cellular protein catabolic process",molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, other, protein catabolic process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,10,4,no,,,,, P126,37,D1,P126_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL005C,COG7,COD5,"Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","transport, vesicle-mediated transport",molecular_function,"mitochondrion, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, mitochondrion, molecular_function, transport, vesicle-mediated transport",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,6,2.3,no,,,,, P126,38,D2,P126_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL006W,PMC1,,Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a,"transport, cellular homeostasis","transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transport, transporter activity, vacuole",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,8,4.6,no,,,,, P126,39,D3,P126_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL007W,BRP1,,"Dubious ORF located in the upstream region of PMA1, deletion leads to polyamine resistance due to downregulation of PMA1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,1,0.5,no,,,,, P126,40,D4,P126_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL010W,,,Putative protein of unknown function; YGL010W is not an essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,6,2.5,no,,,,, P126,41,D5,P126_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL012W,ERG4,,"C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol",other,oxidoreductase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, oxidoreductase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,10,5.1,no,,,,, P126,42,D6,P126_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL013C,PDR1,TPE3;TPE1;TIL1;SMR2;NRA2;CYH3;BOR2;ANT1;AMY1,Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes,"transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,12,5.5,no,,,,, P126,43,D7,P126_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL014W,PUF4,YGL023,"Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors","translation, chromosome organization, transcription, RNA metabolic process",RNA binding,cytoplasm,"RNA binding, RNA metabolic process, cytoplasm, organelle organization and biogenesis, other, transcription",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,6,2.3,no,,,,, P126,44,D8,P126_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL015C,,,Hypothetical protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,12,5.9,no,,,,, P126,45,D9,P126_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL016W,KAP122,PDR6,"Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance",transport,transporter activity,"nucleus, membrane, endomembrane system, cytoplasm","cytoplasm, endomembrane system, membrane, nucleus, other, protein binding, response to chemical stimulus, transport, transporter activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,12,4.2,no,,,,, P126,46,D10,P126_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL019W,CKB1,,"Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases","response to stress, transcription, protein modification process, RNA metabolic process",enzyme regulator activity,"nucleus, nucleolus","RNA metabolic process, anatomical structure morphogenesis, cell cycle, cellular homeostasis, cytoplasm, enzyme regulator activity, nucleolus, nucleus, other, protein modification process, response to stress, transcription",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,8,2.6,no,,,,, P126,47,D11,P126_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL021W,ALK1,,Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins,"cell cycle, protein modification process","transferase activity, protein kinase activity",cellular_component,"cell cycle, cellular_component, protein kinase activity, protein modification process, transferase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,6,2.6,no,,,,, P126,48,D12,P126_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL024W,,SST3,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially/completely overlaps the verified ORF PGD1/YGL025C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,22,12.4,no,,,,, P126,49,E1,P126_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL025C,PGD1,MED3;HRS1,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,4,1.6,no,,,,, P126,50,E2,P126_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL026C,TRP5,,"Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",lyase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, lyase activity, nucleus",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,22,10.2,no,,,,, P126,51,E3,P126_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL027C,CWH41,DER7;GLS1,"Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress","cellular carbohydrate metabolic process, protein modification process",hydrolase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cell wall organization and biogenesis, cytoplasm, endomembrane system, endoplasmic reticulum, hydrolase activity, membrane, protein modification process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,8,2.4,no,,,,, P126,52,E4,P126_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL028C,SCW11,,Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p,cytokinesis,hydrolase activity,cell wall,"cell wall, cytokinesis, hydrolase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,4,1.8,no,,,,, P126,53,E5,P126_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL031C,RPL24A,rp29;YL21;L30A;L24A;RPL30A,"Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate",translation,"RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, ribosome, structural molecule activity, translation",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,2,0.8,no,,,,, P126,54,E6,P126_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL032C,AGA2,a-agglutinin adhesion subunit,"Adhesion subunit of a-agglutinin of a-cells, C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds","conjugation, response to chemical stimulus",protein binding,cell wall,"cell wall, conjugation, protein binding, response to chemical stimulus",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,8,4,no,,,,, P126,55,E7,P126_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL033W,HOP2,,"Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair","meiosis, chromosome organization, cell cycle, DNA metabolic process","DNA binding, protein binding","nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, meiosis, nucleus, organelle organization and biogenesis, protein binding",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,8,4.8,no,,,,, P126,56,E8,P126_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL034C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,138,12,8.7,no,,,,, P126,57,E9,P126_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL035C,MIG1,TDS22;SSN1;CAT4,Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase,"transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, endomembrane system, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, endomembrane system, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,10,4,no,,,,, P126,58,E10,P126_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL036W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YGL036W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,4,2.1,no,,,,, P126,59,E11,P126_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL037C,PNC1,,"Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span","cofactor metabolic process, transcription, vitamin metabolic process, RNA metabolic process",hydrolase activity,"peroxisome, nucleus, cytoplasm","RNA metabolic process, cofactor metabolic process, cytoplasm, hydrolase activity, nucleus, organelle organization and biogenesis, other, peroxisome, transcription, vitamin metabolic process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,8,4.6,no,,,,, P126,60,E12,P126_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL039W,,,Oxidoreductase shown to reduce carbonyl compounds to chiral alcohols,cellular aromatic compound metabolic process,oxidoreductase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, other, oxidoreductase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,16,7.3,no,,,,, P126,61,F1,P126_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL041C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,5,2.2,no,,,,, P126,62,F2,P126_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL042C,,,"Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene DST1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,3,1.4,no,,,,, P126,63,F3,P126_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL043W,DST1,SII;S-II;TFIIS;P37;PPR2,"General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites","transcription, protein complex biogenesis, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,14,6.2,no,,,,, P126,64,F4,P126_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL045W,RIM8,ART9;YGL046W;PAL3,Protein involved in proteolytic activation of Rim101p in response to alkaline pH; interacts with ESCRT-1 subunits Stp22p and Vps28p; essential for anaerobic growth; member of the arrestin-related trafficking adaptor family,"transport, meiosis, vesicle-mediated transport, cell cycle, cellular membrane organization",molecular_function,"membrane, plasma membrane","cellular_component, meiosis, molecular_function, other, protein modification process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,8,4.3,no,,,,, P126,65,F5,P126_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL045W,RIM8,ART9;YGL046W;PAL3,Protein involved in proteolytic activation of Rim101p in response to alkaline pH; interacts with ESCRT-1 subunits Stp22p and Vps28p; essential for anaerobic growth; member of the arrestin-related trafficking adaptor family,"transport, meiosis, vesicle-mediated transport, cell cycle, cellular membrane organization",molecular_function,"membrane, plasma membrane","cellular_component, meiosis, molecular_function, other, protein modification process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,6,3.1,no,,,,, P126,66,F6,P126_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL049C,TIF4632,eIF4G2,"Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4631p",translation,RNA binding,"ribosome, cytoplasm","cytoplasm, ribosome, translation, translation regulator activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,28,14.9,no,,,,, P126,67,F7,P126_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL050W,TYW3,,"tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions",RNA metabolic process,transferase activity,cellular_component,"RNA metabolic process, cellular_component, transferase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,4,2.1,no,,,,, P126,68,F8,P126_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL053W,PRM8,,"Pheromone-regulated protein with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER; member of DUP240 gene family",biological_process,molecular_function,"membrane, endoplasmic reticulum, plasma membrane, cytoplasm","conjugation, endoplasmic reticulum, membrane, molecular_function, plasma membrane, response to chemical stimulus",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,8,3,no,,,,, P126,69,F9,P126_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL054C,ERV14,,"Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon","transport, cell budding, cytokinesis, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, cell cycle",molecular_function,"endomembrane system, cytoplasmic membrane-bounded vesicle, membrane, endoplasmic reticulum, cytoplasm","Golgi apparatus, anatomical structure morphogenesis, cell budding, cytokinesis, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, endoplasmic reticulum, membrane, molecular_function, sporulation, transport, vesicle-mediated transport",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,6,3,no,,,,, P126,70,F10,P126_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL056C,SDS23,,"One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; involved in cell separation during budding",cytokinesis,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,16,6.3,no,,,,, P126,71,F11,P126_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL057C,GEP7,,"Protein of unknown function; null mutant exhibits a respiratory growth defect and synthetic interactions with prohibitin (phb1) and gem1; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,6,2.9,no,,,,, P126,72,F12,P126_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL058W,RAD6,PSO8;UBC2,"Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (as a heterodimer with Rad18p), DSBR and checkpoint control (as a heterodimer with Bre1p), ubiquitin-mediated N-end rule protein degradation (as a heterodimer with Ubr1p","transport, signaling process, transcription, protein modification process, response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process, cellular protein catabolic process",ligase activity,"nucleus, chromosome, cytoplasm","DNA metabolic process, cytoplasm, ligase activity, nucleus, organelle organization and biogenesis, other, protein catabolic process, protein modification process, response to stress",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,22,7.5,no,,,,, P126,73,G1,P126_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL059W,PKP2,,Mitochondrial protein kinase that negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p,protein modification process,"transferase activity, protein kinase activity","mitochondrion, cytoplasm","mitochondrion, other, protein kinase activity, protein modification process, transferase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,5,2.7,no,,,,, P126,74,G2,P126_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL060W,YBP2,,Central kinetochore associated protein that mediates mitotic progression; interacts with several central kinetochore proteins and the centromeric histone Cse4p; role in resistance to oxidative stress; similarity to Ybp1p and Slk19p,cell cycle,molecular_function,"nucleus, chromosome, cytoplasm","cell cycle, chromosome, cytoplasm, molecular_function, nucleus",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,4,2.1,no,,,,, P126,75,G3,P126_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL062W,PYC1,,"Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis","cofactor metabolic process, cellular carbohydrate metabolic process",ligase activity,cytoplasm,"carbohydrate metabolic process, cofactor metabolic process, cytoplasm, ligase activity, vitamin metabolic process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,12,6.3,no,,,,, P126,76,G4,P126_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL063W,PUS2,,"Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification",RNA metabolic process,isomerase activity,"mitochondrion, cytoplasm","RNA metabolic process, isomerase activity, mitochondrion",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,10,3.5,no,,,,, P126,77,G5,P126_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL064C,MRH4,,"Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function",ribosome biogenesis,"helicase activity, hydrolase activity","mitochondrion, cytoplasm","helicase activity, mitochondrion, ribosome biogenesis",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,6,2.5,no,,,,, P126,78,G6,P126_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL066W,SGF73,SCA7,Subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters; null mutant displays defects in premeiotic DNA synthesis,"chromosome organization, protein modification process","transferase activity, structural molecule activity",nucleus,"nucleus, organelle organization and biogenesis, protein modification process, structural molecule activity, transferase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,7,3.5,no,,,,, P126,79,G7,P126_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL067W,NPY1,,"NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes",cofactor metabolic process,hydrolase activity,"peroxisome, cytoplasm","cofactor metabolic process, cytoplasm, hydrolase activity, peroxisome, vitamin metabolic process",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,18,9.4,no,,,,, P126,80,G8,P126_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL070C,RPB9,B12.6;SSU73;SHI,RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site selection and fidelity of transcription,"response to stress, transcription, DNA metabolic process, protein complex biogenesis, RNA metabolic process",molecular_function,nucleus,"DNA metabolic process, RNA metabolic process, nucleotidyltransferase activity, nucleus, response to chemical stimulus, response to stress, transcription, transferase activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,11,6.1,no,,,,, P126,81,G9,P126_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL071W,AFT1,RCS1,Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability,"transport, transcription, RNA metabolic process",DNA binding,"nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, nucleus, transcription, transcription regulator activity, transport",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,10,3.7,no,,,,, P126,82,G10,P126_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL072C,,,"Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene HSF1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,10,3.2,no,,,,, P126,83,G11,P126_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL076C,RPL7A,YL8;L7A;L6A;rp11,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,18,5.7,no,,,,, P126,84,G12,P126_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL077C,HNM1,CTR1,Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol,transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,6,2.8,no,,,,, P126,85,H1,P126_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL078C,DBP3,,Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis,"ribosome biogenesis, RNA metabolic process","helicase activity, hydrolase activity","nucleus, nucleolus","RNA metabolic process, helicase activity, hydrolase activity, nucleolus, organelle organization and biogenesis, ribosome biogenesis",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,8,2.7,no,,,,, P126,86,H2,P126_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL079W,,KIB1,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome; identified as a transcriptional activator in a high-throughput yeast one-hybrid assay,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,3,1.7,no,,,,, P126,87,H3,P126_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P126,88,H4,P126_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL080W,FMP37,,"Putative protein of unknown function; highly conserved across species and orthologous to human gene BRP44L; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,20,9.3,no,,,,, P126,89,H5,P126_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL081W,,,"Putative protein of unknown function; non-essential gene; interacts genetically with CHS5, a gene involved in chitin biosynthesis",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,1,0.6,no,,,,, P126,90,H6,P126_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL082W,,,Putative protein of unknown function; predicted prenylation/proteolysis target of Afc1p and Rce1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YGL082W is not an essential gene,biological_process,molecular_function,"nucleus, membrane fraction, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,10,3,no,,,,, P126,91,H7,P126_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL083W,SCY1,,"Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase",biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm","biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,2,1.1,no,,,,, P126,92,H8,P126_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL084C,GUP1,,Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; proposed to be involved in glycerol transport,"transport, protein modification process, cellular carbohydrate metabolic process, cellular lipid metabolic process",transferase activity,"membrane, endoplasmic reticulum, cytoplasm, plasma membrane","endoplasmic reticulum, lipid metabolic process, membrane, other, plasma membrane, protein modification process, transferase activity, transport",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,14,5.9,no,,,,, P126,93,H9,P126_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL085W,LCL3,,Putative protein of unknown function; mutant has long chronological lifespan; has homology to Staphylococcus aureus nuclease; GFP-fusion protein localizes to mitochondria; is induced in response to the DNA-damaging agent MMS,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,333,76,22.8,no,,,,, P126,94,H10,P126_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL086W,MAD1,,Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p,"transport, signaling process, cell cycle",molecular_function,"nucleus, membrane, endomembrane system, chromosome","cell cycle, endomembrane system, membrane, molecular_function, nucleus, transport",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,49,19.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P126,95,H11,P126_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL087C,MMS2,,"Ubiquitin-conjugating enzyme variant involved in error-free postreplication repair; forms a heteromeric complex with Ubc13p, an active ubiquitin-conjugating enzyme; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p","response to stress, cellular homeostasis, DNA metabolic process, protein modification process, protein complex biogenesis",ligase activity,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, ligase activity, nucleus, other, protein modification process, response to stress",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,14,7.2,no,,,,, P126,96,H12,P126_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL089C,MF(ALPHA)2,,"Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed than MF(ALPHA)2","signaling process, conjugation, response to chemical stimulus",protein binding,extracellular region,"conjugation, extracellular region, protein binding, response to chemical stimulus, signal transduction",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,4,1.9,no,,,,, P127,1,A1,P127_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL090W,LIF1,,Component of the DNA ligase IV complex that mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein,"response to stress, DNA metabolic process",other,"nucleus, chromosome","DNA metabolic process, chromosome, nucleus, other, response to stress",,,07_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,10,4.2,no,,,,, P127,2,A2,P127_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL241C,ZWF1,POS10;MET19,"Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia","response to stress, cofactor metabolic process, cellular carbohydrate metabolic process, response to chemical stimulus",oxidoreductase activity,cytoplasm,"carbohydrate metabolic process, cofactor metabolic process, cytoplasm, oxidoreductase activity, response to chemical stimulus, response to stress, vitamin metabolic process",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,292,10,3.4,no,,,,, P127,3,A3,P127_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL235C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SIN4/YNL236W, a subunit of the mediator complex",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,4,1.9,no,,,,, P127,4,A4,P127_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL233W,BNI4,,"Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p",cytokinesis,protein binding,"cellular bud, cell cortex, site of polarized growth, cytoskeleton, cytoplasm","carbohydrate metabolic process, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, other, protein binding, site of polarized growth",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,28,8.6,no,,,,, P127,5,A5,P127_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL229C,URE2,[URE3],Nitrogen catabolite repression transcriptional regulator that acts by inhibition of GLN3 transcription in good nitrogen source; has glutathione peroxidase activity and can mutate to acquire GST activity; altered form creates [URE3] prion,"transport, response to chemical stimulus, protein modification process","transcription regulator activity, protein binding, oxidoreductase activity",cytoplasm,"cytoplasm, other, protein binding, protein modification process, response to chemical stimulus, transcription regulator activity, transport",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,7,3.8,no,,,,, P127,6,A6,P127_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL228W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps ORF YNL227C/JJJ1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,17,7.9,no,,,,, P127,7,A7,P127_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL226W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene JJJ1/YNL227C",other,molecular_function,cellular_component,"cellular_component, molecular_function, other",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,12,4,no,,,,, P127,8,A8,P127_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL224C,SQS1,PFA1,Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles,"ribosome biogenesis, heterocycle metabolic process, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, nucleus",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,36,12.2,no,,,,, P127,9,A9,P127_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL218W,MGS1,,Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP),"response to stress, DNA metabolic process","DNA binding, protein binding, hydrolase activity, enzyme regulator activity","nucleus, cytoplasm","DNA metabolic process, cytoplasm, enzyme regulator activity, hydrolase activity, nucleus, protein binding, response to stress",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,6,3.2,no,,,,, P127,10,A10,P127_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL217W,,,Hypothetical protein,biological_process,hydrolase activity,"vacuole, cytoplasm","biological_process, cytoplasm, hydrolase activity, vacuole",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,0,0,no,,,,, P127,11,A11,P127_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL215W,IES2,,Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; essential for growth under anaerobic conditions,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,10,7,no,,,,, P127,12,A12,P127_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL214W,PEX17,PAS9,Peroxisomal membrane peroxin and subunit of the docking complex that facilitates the import of peroxisomal matrix proteins; required for peroxisome biogenesis,"transport, peroxisome organization, protein complex biogenesis",protein binding,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, peroxisome, protein binding, transport",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,72,22.1,no,,,,, P127,13,B1,P127_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL212W,VID27,,"Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,12,3.8,no,,,,, P127,14,B2,P127_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL211C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL211C is not an essential gene,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,12,4.6,no,,,,, P127,15,B3,P127_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL210W,MER1,,Protein with RNA-binding motifs required for meiosis-specific mRNA splicing; required for chromosome pairing and meiotic recombination,"meiosis, cell cycle, DNA metabolic process, RNA metabolic process",RNA binding,nucleus,"DNA metabolic process, RNA binding, RNA metabolic process, cell cycle, meiosis, nucleus, other",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,15,4.6,no,,,,, P127,16,B4,P127_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL206C,RTT106,,"Histone chaperone, involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition","chromosome organization, transcription, transposition, RNA metabolic process",protein binding,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, protein binding, transcription, transposition",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,26,9.5,no,,,,, P127,17,B5,P127_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL205C,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,22,9.1,no,,,,, P127,18,B6,P127_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL204C,SPS18,SPX18,"Protein of unknown function, contains a putative zinc-binding domain; expressed during sporulation",sporulation resulting in formation of a cellular spore,molecular_function,cellular_component,"cellular_component, molecular_function, sporulation",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,26,9.4,no,,,,, P127,19,B7,P127_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL202W,SPS19,"2,4-dienoyl-CoA reductase;SPX19","Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate","sporulation resulting in formation of a cellular spore, cellular lipid metabolic process",oxidoreductase activity,"peroxisome, cytoplasm","cytoplasm, lipid metabolic process, oxidoreductase activity, peroxisome, sporulation",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,30,10,no,,,,, P127,20,B8,P127_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL203C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,9,4.9,no,,,,, P127,21,B9,P127_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL201C,PSY2,,Putative subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and the regulatory subunit Psy4p; required for cisplatin and oxaliplatin resistance; putative homolog of mammalian R3,"response to stress, response to chemical stimulus",molecular_function,nucleus,"molecular_function, nucleus, response to chemical stimulus, response to stress",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,255,0,0,no,,,,, P127,22,B10,P127_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL200C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,34,10.6,no,,,,, P127,23,B11,P127_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL199C,GCR2,,Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p,"cellular carbohydrate metabolic process, transcription, generation of precursor metabolites and energy, RNA metabolic process",transcription regulator activity,"nucleus, endomembrane system","RNA metabolic process, carbohydrate metabolic process, generation of precursor metabolites and energy, nucleus, transcription, transcription regulator activity",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,4,1.5,no,,,,, P127,24,B12,P127_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL198C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,18,11,no,,,,, P127,25,C1,P127_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL197C,WHI3,,RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start,"transport, pseudohyphal growth",RNA binding,cytoplasm,"RNA binding, cytoplasm, other, pseudohyphal growth, transport",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,16,7.4,no,,,,, P127,26,C2,P127_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL196C,SLZ1,,Sporulation-specific protein with a leucine zipper motif,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,24,7.5,no,,,,, P127,27,C3,P127_C3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P127,28,C4,P127_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL195C,,,"Putative protein of unknown function; shares a promoter with YNL194C; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,9,4.5,no,,,,, P127,29,C5,P127_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL194C,,,Integral membrane protein required for sporulation and plasma membrane sphingolipid content; has sequence similarity to SUR7 and FMP45; GFP-fusion protein is induced in response to the DNA-damaging agent MMS,sporulation resulting in formation of a cellular spore,molecular_function,"membrane, cell cortex, membrane fraction, endoplasmic reticulum, cytoplasm","cell cortex, cytoplasm, endoplasmic reticulum, membrane, molecular_function, sporulation",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,8,4.2,no,,,,, P127,30,C6,P127_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL193W,,,Putative protein of unknown function; exhibits a two-hybrid interaction with Yhr151cp in a large-scale analysis,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,8,3.1,no,,,,, P127,31,C7,P127_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL191W,DUG3,,"Probable glutamine amidotransferase, forms a complex with Dug1p and Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)","cofactor metabolic process, cellular amino acid and derivative metabolic process","peptidase activity, ligase activity, hydrolase activity",cytoplasm,"cofactor metabolic process, cytoplasm, hydrolase activity, ligase activity, peptidase activity",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,2,0.8,no,,,,, P127,32,C8,P127_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL190W,,,Cell wall protein of unknown function; proposed role as a hydrophilin induced by osmotic stress; contains a putative GPI-attachment site,"response to stress, response to chemical stimulus",molecular_function,cell wall,"cell wall, molecular_function, response to stress",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,12,4,no,,,,, P127,33,C9,P127_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL187W,SWT21,,Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats,RNA metabolic process,molecular_function,nucleus,"molecular_function, nucleus, transport",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,281,5,1.8,no,,,,, P127,34,C10,P127_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL185C,MRPL19,YmL19,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,4,2,no,,,,, P127,35,C11,P127_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL184C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,218,34,15.6,no,,,,, P127,36,C12,P127_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL183C,NPR1,,Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation,other,"transferase activity, protein kinase activity","cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, other, transferase activity",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,281,3,1.1,no,,,,, P127,37,D1,P127_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL180C,RHO5,,"Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity",signaling process,hydrolase activity,"nucleus, membrane fraction, cytoplasm","cytoplasm, hydrolase activity, nucleus, signal transduction",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,270,4,1.5,no,,,,, P127,38,D2,P127_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL179C,,SRF6,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; deletion in cyr1 mutant results in loss of stress resistance",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,1,0.4,no,,,,, P127,39,D3,P127_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL177C,MRPL22,,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation, generation of precursor metabolites and energy, cellular respiration",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, ribosome, structural molecule activity, translation",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,170,7,4.1,no,,,,, P127,40,D4,P127_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL176C,,,"Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p",biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,20,6.1,no,,,,, P127,41,D5,P127_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL175C,NOP13,,Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM),biological_process,RNA binding,"nucleus, nucleolus","RNA binding, nucleolus, nucleus, ribosome biogenesis",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,6,2.4,no,,,,, P127,42,D6,P127_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL173C,MDG1,,Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations,"signaling process, conjugation, response to chemical stimulus",molecular_function,"membrane, plasma membrane","conjugation, molecular_function, plasma membrane, response to chemical stimulus, signal transduction",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,12,6.9,no,,,,, P127,43,D7,P127_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL170W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,20,12.2,no,,,,, P127,44,D8,P127_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL168C,FMP41,,"Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,0,0,no,,,,, P127,45,D9,P127_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL167C,SKO1,ACR1,"Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, forms a complex with Tup1p and Ssn6p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses","transcription, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, transcription, transcription regulator activity",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,20,10.9,no,,,,, P127,46,D10,P127_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL160W,YGP1,,Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p,other,molecular_function,extracellular region,"cell wall, molecular_function, response to chemical stimulus, response to stress",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,15,7.1,no,,,,, P127,47,D11,P127_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL159C,ASI2,,Integral inner nuclear membrane protein that acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals,cellular protein catabolic process,molecular_function,"nucleus, membrane, endomembrane system","endomembrane system, membrane, molecular_function, nucleus, protein catabolic process",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,236,2,0.8,no,,,,, P127,48,D12,P127_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL157W,IGO1,,Protein required for initiation of G0 program; prevents degradation of nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway; phosphorylated by Rim15p; GFP protein localizes to the cytoplasm and nucleus; similar to Igo2p,RNA metabolic process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,40,13,no,,,,, P127,49,E1,P127_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL155W,,,"Putative protein of unknown function, contains DHHC domain, also predicted to have thiol-disulfide oxidoreductase active site",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,36,10.7,no,,,,, P127,50,E2,P127_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL154C,YCK2,,"Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p","transport, cytokinesis, response to chemical stimulus, protein modification process, vesicle-mediated transport, cellular component morphogenesis, cellular membrane organization","transferase activity, protein kinase activity","membrane fraction, cellular bud, membrane, site of polarized growth, plasma membrane","anatomical structure morphogenesis, cellular bud, cytokinesis, membrane organization and biogenesis, other, plasma membrane, protein kinase activity, protein modification process, response to chemical stimulus, site of polarized growth, transferase activity, transport, vesicle-mediated transport",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,4,2.1,no,,,,, P127,51,E3,P127_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL148C,ALF1,,"Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance",protein folding,protein binding,"nucleus, cytoplasm","cytoplasm, nucleus, protein binding, protein folding",,,14_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,12,6.5,no,,,,, P127,52,E4,P127_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL191W,DPH2,,"Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p",protein modification process,molecular_function,cytoplasm,"cytoplasm, molecular_function, protein modification process, ribosome biogenesis",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,16,6.8,no,,,,, P127,53,E5,P127_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL197C,PEX1,PAS1,AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis,"transport, signaling process, peroxisome organization","protein binding, hydrolase activity","peroxisome, membrane fraction, cytoplasm","hydrolase activity, membrane fraction, organelle organization and biogenesis, other, peroxisome, protein binding, signal transduction, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,3,1.2,no,,,,, P127,54,E6,P127_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL198C,PTK1,POT1;YKT9;YKL199C;STK1;KKT8,Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein,transport,"transferase activity, protein kinase activity",cellular_component,"cellular_component, protein kinase activity, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,24,14.1,no,,,,, P127,55,E7,P127_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL198C,PTK1,POT1;YKT9;YKL199C;STK1;KKT8,Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein,transport,"transferase activity, protein kinase activity",cellular_component,"cellular_component, protein kinase activity, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,24,11.3,no,,,,, P127,56,E8,P127_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL200C,,,,,,,,,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P127,57,E9,P127_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL205W,LOS1,,Nuclear pore protein involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after their retrograde import from the cytoplasm,"transport, RNA metabolic process","RNA binding, protein binding","nucleus, mitochondrion, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, mitochondrion, nucleus, protein binding, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,8,2.7,no,,,,, P127,58,E10,P127_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL206C,ADD66,POC2;PBA2,Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly,"protein complex biogenesis, cellular protein catabolic process",molecular_function,cytoplasm,"cytoplasm, molecular_function, other, protein catabolic process",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,9,4.2,no,,,,, P127,59,E11,P127_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL207W,AIM27,EMC3;LRC3,Member of a transmembrane complex required for efficient folding of proteins in the ER; required for respiratory growth; null mutant displays induction of the unfolded protein response,protein folding,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,11,6.3,no,,,,, P127,60,E12,P127_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL208W,CBT1,SOC1,"Protein involved in 5' end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p","protein complex biogenesis, RNA metabolic process",molecular_function,"mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, molecular_function, other",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,126,36,28.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P127,61,F1,P127_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL211C,TRP3,,"Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",lyase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, lyase activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,32,14.4,no,,,,, P127,62,F2,P127_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL212W,SAC1,RSD1,"Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmembrane protein localizes to ER and Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance",cellular lipid metabolic process,hydrolase activity,"endomembrane system, mitochondrion, membrane, mitochondrial envelope, endoplasmic reticulum, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, endoplasmic reticulum, hydrolase activity, lipid metabolic process, membrane, mitochondrial envelope, mitochondrion",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,262,6,2.3,no,,,,, P127,63,F3,P127_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL213C,DOA1,ZZZ4;UFD3,"WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase","response to stress, DNA metabolic process, cellular protein catabolic process",protein binding,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, nucleus, protein binding, protein catabolic process, response to stress",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,281,12,4.3,no,,,,, P127,64,F4,P127_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL214C,YRA2,,"Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus",transport,RNA binding,nucleus,"RNA binding, nucleus, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,6,1.8,no,,,,, P127,65,F5,P127_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL216W,URA1,,"Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid","heterocycle metabolic process, cellular aromatic compound metabolic process",oxidoreductase activity,"membrane, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, membrane, oxidoreductase activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,50,15.5,no,,,,, P127,66,F6,P127_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL217W,JEN1,,"Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, plasma membrane, transport, transporter activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,12,5,no,,,,, P127,67,F7,P127_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL218C,SRY1,,"3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required in the presence of hydroxyaspartate; highly similar to mouse serine racemase (Srr) but has no serine racemase activity",cellular amino acid and derivative metabolic process,lyase activity,cellular_component,"amino acid and derivative metabolic process, cellular_component, lyase activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,42,17.5,no,,,,, P127,68,F8,P127_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL221W,MCH2,,"Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,28,9.1,no,,,,, P127,69,F9,P127_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL222C,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; similar to transcriptional regulators from the zinc cluster (binuclear cluster) family; null mutant is sensitive to caffeine",biological_process,DNA binding,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,2,0.7,no,,,,, P127,70,F10,P127_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR001C,VPS1,VPT26;VPL1;SPO15;LAM1;GRD1,"Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, late Golgi-retention of some proteins, regulating peroxisome biogenesis","transport, cytoskeleton organization, peroxisome organization",hydrolase activity,"peroxisome, membrane fraction, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, cytoskeleton organization and biogenesis, hydrolase activity, membrane, membrane fraction, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, peroxisome, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,235,10,4.3,no,,,,, P127,71,F11,P127_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR003W,OSH6,,"Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery","transport, vesicle-mediated transport, cellular membrane organization",lipid binding,"cell cortex, membrane fraction, membrane, endoplasmic reticulum, cytoplasm, plasma membrane","anatomical structure morphogenesis, cytoplasm, lipid binding, lipid metabolic process, membrane fraction, membrane organization and biogenesis, other, transport, vesicle-mediated transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,7,3.6,no,,,,, P127,72,F12,P127_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR005C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,34,14.2,no,,,,, P127,73,G1,P127_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR006C,MRPL13,YmL13;YK105,"Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,306,10,3.3,no,,,,, P127,74,G2,P127_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR007W,MEH1,GSE2;EGO1,"Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification","cellular homeostasis, cellular membrane organization",molecular_function,"membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, membrane, membrane organization and biogenesis, molecular_function, vacuole",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,10,5.2,no,,,,, P127,75,G3,P127_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR009C,FOX2,POX2,Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities,cellular lipid metabolic process,"lyase activity, oxidoreductase activity","peroxisome, cytoplasm","cytoplasm, lipid metabolic process, lyase activity, oxidoreductase activity, peroxisome",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,6,3.2,no,,,,, P127,76,G4,P127_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR011C,,TOS5,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,16,5.2,no,,,,, P127,77,G5,P127_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR012C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PRY2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,11,6.3,no,,,,, P127,78,G6,P127_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR013W,PRY2,YFW12,Protein of unknown function,biological_process,molecular_function,"extracellular region, vacuole, cytoplasm","biological_process, cytoplasm, extracellular region, molecular_function, vacuole",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,2,0.9,no,,,,, P127,79,G7,P127_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR014C,YPT52,,"Rab family GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis","transport, vesicle-mediated transport, cellular membrane organization",hydrolase activity,cytoplasm,"cytoplasm, hydrolase activity, membrane organization and biogenesis, transport, vesicle-mediated transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,4,2,no,,,,, P127,80,G8,P127_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR015C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,18,5.6,no,,,,, P127,81,G9,P127_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR016W,FCJ1,AIM28;FMP13,Mitochondrial inner membrane protein involved in formation and molecular structure of crista junctions; impairs oligomerization of F1F0-ATP synthase; null shows altered mitochondrial morphology and abnormal mitochondrial genome maintenance,"mitochondrion organization, cellular membrane organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,18,6.3,no,,,,, P127,82,G10,P127_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR017C,,,Putative protein of unknown function; contains a RING finger motif,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,0,0,no,,,,, P127,83,G11,P127_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR018C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,30,8.9,no,,,,, P127,84,G12,P127_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR020W,VPS51,VPS67;API3;WHI6,"Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP) complex to the SNARE Tlg1p","transport, cell budding, vesicle organization, vesicle-mediated transport",protein binding,"cytoplasmic membrane-bounded vesicle, Golgi apparatus, cytoplasm","Golgi apparatus, cell budding, cytoplasm, cytoplasmic membrane-bounded vesicle, organelle organization and biogenesis, other, protein binding, transport, vesicle-mediated transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,4,2,no,,,,, P127,85,H1,P127_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR021W,ALY1,ART6,Protein proposed to regulate the endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its target in the plasma membrane; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,"transport, vesicle-mediated transport, cellular membrane organization",protein binding,cytoplasm,"biological_process, cytoplasm, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,34,11.4,no,,,,, P127,86,H2,P127_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR024C,DBP7,,Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis; essential for growth under anaerobic conditions,"ribosome biogenesis, RNA metabolic process","helicase activity, hydrolase activity","nucleus, nucleolus","RNA metabolic process, helicase activity, hydrolase activity, nucleolus, organelle organization and biogenesis, ribosome biogenesis",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,10,4.1,no,,,,, P127,87,H3,P127_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P127,88,H4,P127_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR026C,GCN3,AAS2,"Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression",translation,"RNA binding, enzyme regulator activity",cytoplasm,"cytoplasm, enzyme regulator activity, other, translation, translation regulator activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,2,0.7,no,,,,, P127,89,H5,P127_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR030W,GMH1,MSG1,"Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting",transport,molecular_function,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, membrane, molecular_function, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,20,11,no,,,,, P127,90,H6,P127_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR031C,SPO14,PLD1,"Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis","transport, response to chemical stimulus, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, cellular lipid metabolic process, conjugation, cellular component morphogenesis","lipid binding, hydrolase activity","membrane, cytoplasm","anatomical structure morphogenesis, conjugation, cytoplasm, hydrolase activity, lipid binding, lipid metabolic process, membrane, response to chemical stimulus, sporulation, transport, vesicle-mediated transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,9,5.3,no,,,,, P127,91,H7,P127_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR032W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,6,3.5,no,,,,, P127,92,H8,P127_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR033C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene DAL80",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,8,4.4,no,,,,, P127,93,H9,P127_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR035C,OPI8,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene DID2/YKR035W-A",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,24,9.6,no,,,,, P127,94,H10,P127_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR042W,UTH1,,"Mitochondrial outer membrane and cell wall localized SUN family member involved in cell wall biogenesis and required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, and cell death","transcription, chromosome organization, RNA metabolic process",molecular_function,"mitochondrion, cell wall, membrane, mitochondrial envelope, cytoplasm","RNA metabolic process, cell wall, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, transcription",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,3,1.6,no,,,,, P127,95,H11,P127_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR043C,,,"Metal-independent fructose 1,6-bisphosphatase, may play a role in gluconeogenesis under metal-limiting conditions; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus",biological_process,hydrolase activity,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,4,2.3,no,,,,, P127,96,H12,P127_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR044W,UIP5,,"Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates",biological_process,molecular_function,"nucleus, endomembrane system","biological_process, endomembrane system, molecular_function, nucleus",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,20,10.5,no,,,,, P128,1,A1,P128_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR045C,,,Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,255,1,0.4,no,,,,, P128,2,A2,P128_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR047W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene NAP1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,2,1,no,,,,, P128,3,A3,P128_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR048C,NAP1,,Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamics during mitosis; controls bud morphogenesis; involved in the transport of H2A and H2B histones to the nucleus; phosphorylated by CK2,"transport, cell budding, chromosome organization, cell cycle",protein binding,"nucleus, chromosome, cytoplasm","cell budding, cell cycle, chromosome, cytoplasm, nucleus, organelle organization and biogenesis, protein binding, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,180,5,2.8,no,,,,, P128,4,A4,P128_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR049C,FMP46,,"Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,oxidoreductase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, oxidoreductase activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,198,7,3.5,no,,,,, P128,5,A5,P128_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR050W,TRK2,RPD2,Component of the Trk1p-Trk2p potassium transport system,cellular homeostasis,transporter activity,"membrane, plasma membrane","cellular homeostasis, plasma membrane, transporter activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,201,8,4,no,,,,, P128,6,A6,P128_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR051W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,322,8,2.5,no,,,,, P128,7,A7,P128_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR052C,MRS4,,"Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs3p; active under low-iron conditions; may transport other cations","transport, RNA metabolic process",transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,195,25,12.8,no,,,,, P128,8,A8,P128_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR054C,DYN1,PAC6;DHC1,"Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p","transport, cytoskeleton organization, chromosome segregation, chromosome organization, cell cycle","motor activity, hydrolase activity","cell cortex, cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoskeleton, cytoskeleton organization and biogenesis, motor activity, organelle organization and biogenesis, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,3,1.4,no,,,,, P128,9,A9,P128_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR056W,TRM2,RNC1;NUD1;NUC2,"tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair","response to stress, DNA metabolic process, RNA metabolic process","transferase activity, hydrolase activity",cellular_component,"DNA metabolic process, RNA metabolic process, cellular_component, hydrolase activity, response to stress, ribosome biogenesis, transferase activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,302,12,4,no,,,,, P128,10,A10,P128_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR057W,RPS21A,YS25;S26A;S21A;RPS25,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,227,3,1.3,no,,,,, P128,11,A11,P128_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR058W,GLG1,,"Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,cellular_component,"carbohydrate metabolic process, cellular_component, generation of precursor metabolites and energy, transferase activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,207,9,4.3,no,,,,, P128,12,A12,P128_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR059W,TIF1,eIF4A,"Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G",translation,"RNA binding, helicase activity, hydrolase activity","ribosome, cytoplasm","cytoplasm, helicase activity, hydrolase activity, ribosome, translation, translation regulator activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,300,4,1.3,no,,,,, P128,13,B1,P128_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR060W,UTP30,,Subunit of U3-containing 90S preribosome complex involved in production of 18S rRNA and assembly of small ribosomal subunit,ribosome biogenesis,molecular_function,"nucleus, nucleolus","RNA metabolic process, cytoplasm, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,6,3,no,,,,, P128,14,B2,P128_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR061W,KTR2,,Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family,"cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cell wall organization and biogenesis, protein modification process, transferase activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,204,20,9.8,no,,,,, P128,15,B3,P128_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR064W,OAF3,,"Zinc cluster protein; regulates transcription in response to oleate levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","cellular lipid metabolic process, transcription",transcription regulator activity,"nucleus, mitochondrion, cytoplasm","cytoplasm, lipid metabolic process, mitochondrion, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,191,31,16.2,no,,,,, P128,16,B4,P128_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR065C,PAM17,FMP18,Constituent of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); proposed alternatively to be a component of the import motor (PAM complex) or to interact with and modulate the core TIM23 complex,"transport, mitochondrion organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, transport",,,11_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,247,18,7.3,no,,,,, P128,17,B5,P128_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR242W,AMD2,,Putative amidase,biological_process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,204,14,6.9,no,,,,, P128,18,B6,P128_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR244W,PEX5,PAS10,"Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins, required for peroxisomal matrix protein import; also proposed to have PTS1-receptor independent functions","transport, peroxisome organization, protein complex biogenesis",protein binding,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, other, peroxisome, protein binding, transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,417,30,7.2,no,,,,, P128,19,B7,P128_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR245W,MNN10,REC41;SLC2;BED1,"Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family","cellular carbohydrate metabolic process, cytokinesis, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, carbohydrate metabolic process, cell wall organization and biogenesis, cytokinesis, cytoplasm, protein modification process, transferase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,4,2,no,,,,, P128,20,B8,P128_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR247W,VHS1,,"Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p","cell cycle, protein modification process","transferase activity, protein kinase activity",cytoplasm,"cell cycle, cytoplasm, protein kinase activity, protein modification process, transferase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,6,2.8,no,,,,, P128,21,B9,P128_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR248C,,,"Putative protein of unknown function; sequence similarity to bacterial and human gluconokinase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; upregulated by deletion of the RNAP-II associated factor, PAF1",cellular carbohydrate metabolic process,transferase activity,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,4,1.5,no,,,,, P128,22,B10,P128_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR249C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,6,1.9,no,,,,, P128,23,B11,P128_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR250C,,,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,278,16,5.8,no,,,,, P128,24,B12,P128_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR251W,PAM1,,"Essential protein of unknown function; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype",pseudohyphal growth,molecular_function,"cellular bud, site of polarized growth","cellular bud, molecular_function, pseudohyphal growth, site of polarized growth",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,5,2.9,no,,,,, P128,25,C1,P128_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR252W,BTT1,,Beta3 subunit of the heterotrimeric nascent polypeptide-associated complex which binds ribosomes via its beta-subunits in close proximity to nascent polypeptides; interacts with Caf130p of the CCR4-NOT complex; similar to human BTF3,protein folding,protein binding,"nucleus, cytoplasm","cytoplasm, nucleus, protein binding, protein folding, ribosome",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,1,0.5,no,,,,, P128,26,C2,P128_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR253C,MET32,,"Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p",cellular amino acid and derivative metabolic process,"transcription regulator activity, DNA binding",nucleus,"DNA binding, amino acid and derivative metabolic process, nucleus, transcription regulator activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,54,16.8,no,,,,, P128,27,C3,P128_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR254W,CHL4,MCM17;CTF17,"Outer kinetochore protein required for chromosome stability; involved in new kinetochore assembly and sister chromatid cohesion; peripheral component of the Ctf19 kinetochore subcomplex that interacts with Ctf19p, Ctf3p, Iml3p and Mif2p","protein complex biogenesis, chromosome segregation, meiosis, chromosome organization, cell cycle",structural molecule activity,"nucleus, chromosome","DNA binding, chromosome, nucleus, other",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,29,12.7,no,,,,, P128,28,C4,P128_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P128,29,C5,P128_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR255C,RMD5,GID2,"Conserved protein that has an E3-like ubiquitin ligase activity necessary for polyubiquitination and degradation of the gluconeogenic enzyme fructose-1,6-bisphosphatase; also required for sporulation; has a degenerate RING finger domain","cellular carbohydrate metabolic process, protein modification process, cellular protein catabolic process",ligase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, ligase activity, other, protein catabolic process, protein modification process",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,392,2,0.5,no,,,,, P128,30,C6,P128_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR256C,CTA1,,"Catalase A, breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation","response to stress, response to chemical stimulus",oxidoreductase activity,"peroxisome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity, peroxisome, response to chemical stimulus, response to stress",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,6,2.8,no,,,,, P128,31,C7,P128_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR257C,RKM4,SET7;RMS1,Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (lysine 55); nuclear SET-domain containing protein,protein modification process,transferase activity,nucleus,"biological_process, molecular_function, nucleus",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,2,0.6,no,,,,, P128,32,C8,P128_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR258C,HSP78,,Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; able to prevent the aggregation of misfolded proteins as well as resolubilize protein aggregates,"transport, mitochondrion organization, translation, response to stress, protein folding","hydrolase activity, protein binding","mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, organelle organization and biogenesis, protein binding, protein folding, response to stress, transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,3,1.5,no,,,,, P128,33,C9,P128_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR259C,YAP6,HAL7,Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expression of genes involved in carbohydrate metabolism,"transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,293,22,7.5,no,,,,, P128,34,C10,P128_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR260C,SWM1,,"Subunit of the anaphase-promoting complex, which is an E3 ubiquitin ligase that regulates the metaphase-anaphase transition and exit from mitosis; required for activation of the daughter-specific gene expression and spore wall maturation","sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cell cycle, protein modification process, cellular protein catabolic process",molecular_function,nucleus,"cell cycle, cell wall organization and biogenesis, molecular_function, nucleus, protein catabolic process, protein modification process, sporulation",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,8,2.8,no,,,,, P128,35,C11,P128_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR261C,EXG2,,"Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor",fungal-type cell wall organization,hydrolase activity,cell wall,"cell wall, cell wall organization and biogenesis, hydrolase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,2,0.6,no,,,,, P128,36,C12,P128_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR262W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole and is induced in response to the DNA-damaging agent MMS; gene expression increases in response to Zymoliase treatment,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,6,2.2,no,,,,, P128,37,D1,P128_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR263C,DIN7,DIN3,"Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination","response to stress, DNA metabolic process",hydrolase activity,"mitochondrion, cytoplasm","DNA metabolic process, hydrolase activity, mitochondrion, response to stress",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,273,7,2.6,no,,,,, P128,38,D2,P128_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR264C,AKR1,,Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats,"transport, signaling process, response to chemical stimulus, protein modification process, vesicle-mediated transport, conjugation, cellular membrane organization",transferase activity,"membrane, Golgi apparatus, cytoplasm","conjugation, membrane, membrane organization and biogenesis, protein modification process, response to chemical stimulus, signal transduction, transferase activity, transport, vesicle-mediated transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,333,13,3.9,no,,,,, P128,39,D3,P128_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR265W,PEX10,PAS4,"Peroxisomal membrane E3 ubiquitin ligase, required for for Ubc4p-dependent Pex5p ubiquitination and peroxisomal matrix protein import; contains zinc-binding RING domain; mutations in human homolog cause various peroxisomal disorders","transport, peroxisome organization, protein modification process","protein binding, ligase activity","peroxisome, membrane, cytoplasm","cytoplasm, ligase activity, membrane, organelle organization and biogenesis, peroxisome, protein binding, protein modification process, transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,4,1.6,no,,,,, P128,40,D4,P128_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR266C,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments;green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; contains a RING finger domain",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,9,3.3,no,,,,, P128,41,D5,P128_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR268W,MSW1,mitochondrial tryptophanyl-tRNA synthetase,Mitochondrial tryptophanyl-tRNA synthetase,"mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,1,0.3,no,,,,, P128,42,D6,P128_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR270W,CCC2,,"Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases","transport, cellular homeostasis","hydrolase activity, transporter activity","endomembrane system, cytoplasmic membrane-bounded vesicle, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cellular homeostasis, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, hydrolase activity, membrane, other, transport, transporter activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,4,1.6,no,,,,, P128,43,D7,P128_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR272W,GLO2,,"Cytoplasmic glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate",cellular carbohydrate metabolic process,hydrolase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, hydrolase activity, response to chemical stimulus",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,303,2,0.7,no,,,,, P128,44,D8,P128_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR273W,DON1,,"Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II","meiosis, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cell cycle",molecular_function,"membrane, cytoskeleton","cell wall organization and biogenesis, cytoskeleton, meiosis, membrane, molecular_function, sporulation",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,315,24,7.6,no,,,,, P128,45,D9,P128_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR274C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,10,4,no,,,,, P128,46,D10,P128_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR275W,BSC2,,"Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,2,1,no,,,,, P128,47,D11,P128_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR276C,PMP3,SNA1,"Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential","transport, cellular homeostasis",molecular_function,"membrane, plasma membrane","cellular homeostasis, molecular_function, plasma membrane, transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,8,2.9,no,,,,, P128,48,D12,P128_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR277C,MTH1,HTR1;DGT1;BPC1,"Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation","transport, signaling process",molecular_function,cellular_component,"cellular_component, molecular_function, signal transduction, transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,4,1.4,no,,,,, P128,49,E1,P128_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR278C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,277,9,3.2,no,,,,, P128,50,E2,P128_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR279W,RNH202,Rnh2B,"Ribonuclease H2 subunit, required for RNase H2 activity; related to human AGS2 that causes Aicardi-Goutieres syndrome","DNA metabolic process, RNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, hydrolase activity, nucleus, other",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,255,3,1.2,no,,,,, P128,51,E3,P128_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR281C,PHM6,,"Protein of unknown function, expression is regulated by phosphate levels",biological_process,molecular_function,"vacuole, cytoplasm","cytoplasm, molecular_function, response to chemical stimulus, vacuole",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,2,0.7,no,,,,, P128,52,E4,P128_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR282C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,10,4.8,no,,,,, P128,53,E5,P128_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR283C,GCN2,AAS102;NDR2;AAS1,"Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control","signaling process, translation, cellular amino acid and derivative metabolic process, protein modification process, response to stress, cell cycle","transferase activity, protein kinase activity, protein binding","ribosome, cytoplasm","amino acid and derivative metabolic process, cytoplasm, protein kinase activity, protein modification process, ribosome, transferase activity, translation",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,6,3.3,no,,,,, P128,54,E6,P128_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR284C,DPP1,ZRG1,"Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism","signaling process, cellular lipid metabolic process",hydrolase activity,"membrane, vacuole, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, membrane, signal transduction, vacuole",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,6,2,no,,,,, P128,55,E7,P128_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR285W,ZIP1,,Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate,"meiosis, chromosome organization, cell cycle, DNA metabolic process",protein binding,"nucleus, chromosome","cell cycle, chromosome, meiosis, nucleus, organelle organization and biogenesis, other, protein binding",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,299,3,1,no,,,,, P128,56,E8,P128_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR286C,,,Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,285,1,0.4,no,,,,, P128,57,E9,P128_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR287W,INM2,,"Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy",cellular carbohydrate metabolic process,hydrolase activity,cellular_component,"carbohydrate metabolic process, cellular_component, hydrolase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,2,1.1,no,,,,, P128,58,E10,P128_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR289C,RTT103,,"Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in transcription termination by RNA polymerase II, has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition","transcription, transposition, RNA metabolic process",molecular_function,cellular_component,"DNA metabolic process, RNA metabolic process, cellular_component, molecular_function, transcription, transposition",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,40,22,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P128,59,E11,P128_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR291W,HRQ1,,Putative RecQ helicase; belongs to the widely conserved RecQ family of proteins which are involved in maintaining genomic integrity; similar to the human RecQ4p implicated in Rothmund-Thomson syndrome(RTS),biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,24,11.6,no,,,,, P128,60,E12,P128_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR293C,SSD1,SRK1;RLT1;MCS1;CLA1,"Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence",fungal-type cell wall organization,RNA binding,cytoplasm,"RNA binding, cell wall organization and biogenesis, cytoplasm, other, response to chemical stimulus",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,6,1.9,no,,,,, P128,61,F1,P128_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR294C,DPL1,BST1,"Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate","response to stress, signaling process, cellular lipid metabolic process",lyase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, lyase activity, response to stress, signal transduction",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,223,4,1.8,no,,,,, P128,62,F2,P128_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR295C,HDA2,PLO2,Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex containing an Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance,"chromosome organization, transcription, protein modification process, RNA metabolic process","DNA binding, hydrolase activity","nucleus, chromosome","RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, other, protein modification process, transcription",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,3,1.2,no,,,,, P128,63,F3,P128_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR296W,MHR1,XTC1,Protein involved in homologous recombination in mitochondria; required for recombination-dependent mtDNA partitioning; involved in stimulation of mitochondrial DNA replication in response to oxidative stress,"mitochondrion organization, transcription, response to chemical stimulus, response to stress, DNA metabolic process, RNA metabolic process",DNA binding,"nucleus, mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,317,1,0.3,no,,,,, P128,64,F4,P128_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR297W,SUR2,SYR2,"Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis",cellular lipid metabolic process,oxidoreductase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, oxidoreductase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,12,4.5,no,,,,, P128,65,F5,P128_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR298C,ATP5,oligomycin sensitivity-conferring protein;OSC1,"Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated","transport, heterocycle metabolic process",transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,276,6,2.2,no,,,,, P128,66,F6,P128_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR300C,PRO1,,"Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis","cellular amino acid and derivative metabolic process, heterocycle metabolic process",transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, ribosome biogenesis, transferase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,13,5.6,no,,,,, P128,67,F7,P128_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR304C,CPR5,CYP5,"Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER",biological_process,isomerase activity,"endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endoplasmic reticulum, isomerase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,4,2.1,no,,,,, P128,68,F8,P128_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR305C,HNT2,APH1,Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins,heterocycle metabolic process,hydrolase activity,"nucleus, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, nucleus, other",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,241,1,0.4,no,,,,, P128,69,F9,P128_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR306C,,,F-box protein of unknown function; interacts with Sgt1p via a Leucine-Rich Repeat (LRR) domain,cellular protein catabolic process,protein binding,other,"other, protein binding, protein catabolic process",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,1,0.5,no,,,,, P128,70,F10,P128_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR307W,,,Putative protein of unknown function,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,1,0.4,no,,,,, P128,71,F11,P128_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR309C,GIC2,,"Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region","cell budding, signaling process, cytokinesis, cell cycle","lipid binding, enzyme regulator activity, protein binding","cell cortex, cytoskeleton, cellular bud, membrane, site of polarized growth, cytoplasm, plasma membrane","anatomical structure morphogenesis, cell budding, cell cortex, cell cycle, cellular bud, cytokinesis, cytoplasm, cytoskeleton, enzyme regulator activity, lipid binding, other, plasma membrane, signal transduction, site of polarized growth",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,1,0.5,no,,,,, P128,72,F12,P128_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR310C,SUM1,,"Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint","transcription, cell cycle, DNA metabolic process, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, RNA metabolic process, cell cycle, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,4,2.8,no,,,,, P128,73,G1,P128_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR312W,SSF2,,"Protein required for ribosomal large subunit maturation, functionally redundant with Ssf1p; member of the Brix family","conjugation, ribosome biogenesis",RNA binding,"nucleus, nucleolus","RNA binding, conjugation, nucleolus, organelle organization and biogenesis, ribosome biogenesis",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,257,1,0.4,no,,,,, P128,74,G2,P128_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR313C,PIB1,,"RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain",protein modification process,"lipid binding, ligase activity","membrane, vacuole, cytoplasm","cytoplasm, ligase activity, lipid binding, membrane, protein modification process, vacuole",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,3,1.4,no,,,,, P128,75,G3,P128_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR314C,RAD34,,Protein involved in nucleotide excision repair (NER); homologous to RAD4,"response to stress, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, molecular_function, nucleus, response to stress",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,295,3,1,no,,,,, P128,76,G4,P128_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR315C,IPK1,GSL1,"Inositol 1,3,4,5,6-pentakisphosphate 2-kinase, nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate (phytate), which is integral to cell function; has 2 motifs conserved in other fungi; ipk1 gle1 double mutant is inviable","cellular carbohydrate metabolic process, RNA metabolic process",transferase activity,nucleus,"DNA metabolic process, nucleus, other, transferase activity, transposition",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,5,2.8,no,,,,, P128,77,G5,P128_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR316W,OMS1,,Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations,biological_process,transferase activity,"mitochondrial envelope, mitochondrion, cytoplasm","biological_process, mitochondrial envelope, mitochondrion, transferase activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,2,1,no,,,,, P128,78,G6,P128_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR317W,HIM1,,Protein of unknown function involved in DNA repair,"response to stress, DNA metabolic process",molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function, response to stress",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,4,1.5,no,,,,, P128,79,G7,P128_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR318W,MCM21,CTF5,"Protein involved in minichromosome maintenance; component of the COMA complex (Ctf19p, Okp1p, Mcm21p, Ame1p) that bridges kinetochore subunits that are in contact with centromeric DNA and the subunits bound to microtubules","chromosome organization, cell cycle, chromosome segregation",protein binding,"nucleus, chromosome","chromosome, nucleus, other, protein binding",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,3,1.2,no,,,,, P128,80,G8,P128_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR319C,,FIT2A,"Putative protein of unknown function, identified as an ortholog of the highly conserved FIT family of proteins involved in triglyceride droplet biosynthesis; interacts with Sst2p and Hsp82p in high-throughput two-hybrid screens",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,4,2.4,no,,,,, P128,81,G9,P128_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR320C,SWA2,BUD24;AUX1,Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles,other,protein binding,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, organelle organization and biogenesis, protein binding",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,3,1.4,no,,,,, P128,82,G10,P128_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR321W,ASP1,,"Cytosolic L-asparaginase, involved in asparagine catabolism",cellular amino acid and derivative metabolic process,hydrolase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, hydrolase activity, other",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,6,2.1,no,,,,, P128,83,G11,P128_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR322W,MRPL35,YmL35,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,4,1.6,no,,,,, P128,84,G12,P128_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR323C,PEP7,VPT19;VPS19;VPL21;VAC1,"Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance","vacuole organization, transport, vesicle-mediated transport, vesicle organization, cellular membrane organization",lipid binding,"membrane, cytoplasm","cytoplasm, lipid binding, membrane, membrane organization and biogenesis, organelle organization and biogenesis, transport, vesicle-mediated transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,232,20,8.6,no,,,,, P128,85,H1,P128_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR329C,PEX3,PAS3,Peroxisomal membrane protein (PMP) required for proper localization and stability of PMPs; anchors peroxisome retention factor Inp1p at the peroxisomal membrane; interacts with Pex19p,"transport, peroxisome organization",protein binding,"peroxisome, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, organelle organization and biogenesis, peroxisome, protein binding, transport",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,229,20,8.7,no,,,,, P128,86,H2,P128_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR330W,UBX5,,UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p,cellular protein catabolic process,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, protein catabolic process",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,10,5.9,no,,,,, P128,87,H3,P128_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P128,88,H4,P128_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR332W,IRC3,,Putative RNA helicase of the DEAH/D-box family; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion,biological_process,"helicase activity, hydrolase activity","mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,90,31.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P128,89,H5,P128_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR333C,,,Putative protein of unknown function,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,2,0.7,no,,,,, P128,90,H6,P128_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR334W,SWR1,,"Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A",chromosome organization,structural molecule activity,"nucleus, chromosome","nucleus, organelle organization and biogenesis, structural molecule activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,8,3.2,no,,,,, P128,91,H7,P128_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR335W,MSN5,STE21;KAP142,"Karyopherin involved in nuclear import and export of proteins, including import of replication protein A and export of Swi6p, Far1p, and Pho4p; required for re-export of mature tRNAs after their retrograde import from the cytoplasm",transport,"transporter activity, protein binding",nucleus,"nucleus, protein binding, transport, transporter activity",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,3,1.6,no,,,,, P128,92,H8,P128_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR336W,,,Putative protein of unknown function; sumoylated under stress conditions in a genome wide study; YDR336W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,356,6,1.7,no,,,,, P128,93,H9,P128_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR337W,MRPS28,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation","RNA binding, structural molecule activity","ribosome, mitochondrion, cytoplasm","RNA binding, cytoplasm, mitochondrion, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,04_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,7,3.7,no,,,,, P128,94,H10,P128_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL001W,,,Putative protein of unknown function; contains a BTB/POZ domain which generally function in protein interactions; deletion slightly improved competitive fitness in rich media; GFP-tagged protein is localized to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,4,1.8,no,,,,, P128,95,H11,P128_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL002C,INP51,SJL1,"Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth",cellular lipid metabolic process,hydrolase activity,"membrane fraction, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, membrane fraction",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,195,7,3.6,no,,,,, P128,96,H12,P128_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL005W,EPS1,,"ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family",cellular protein catabolic process,"isomerase activity, protein binding","membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, isomerase activity, membrane, other, protein binding, protein catabolic process",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,222,6,2.7,no,,,,, P129,1,A1,P129_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL011W,TIR3,YIB1,Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth,biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,8,4.1,no,,,,, P129,2,A2,P129_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL012W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,6,2.1,no,,,,, P129,3,A3,P129_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL013C,PDR11,,"ATP-binding cassette (ABC) transporter, multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromisedregulated by Pdr1p; required for anaerobic growth",transport,"transporter activity, hydrolase activity",membrane,"hydrolase activity, membrane, transport, transporter activity",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,241,9,3.7,no,,,,, P129,4,A4,P129_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL014W,MNT3,,"Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation","cellular carbohydrate metabolic process, protein modification process",transferase activity,cellular_component,"cellular_component, protein modification process, transferase activity",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,12,4.8,no,,,,, P129,5,A5,P129_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL015W,BAR1,SST1,"Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest","conjugation, response to chemical stimulus","peptidase activity, hydrolase activity",other,"conjugation, hydrolase activity, other, peptidase activity, response to chemical stimulus, signal transduction",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,8,3.6,no,,,,, P129,6,A6,P129_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL016W,SNL1,,Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein,"protein folding, nucleus organization",molecular_function,"nucleus, endomembrane system, mitochondrion, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, mitochondrion, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, other, protein folding",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,8,3.1,no,,,,, P129,7,A7,P129_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL017C,VID28,YIL017W;GID5,"Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm","cellular carbohydrate metabolic process, sporulation resulting in formation of a cellular spore, transcription, cellular protein catabolic process, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, carbohydrate metabolic process, cytoplasm, molecular_function, nucleus, other, protein catabolic process, response to chemical stimulus, sporulation, transcription",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,8,4.6,no,,,,, P129,8,A8,P129_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL020C,HIS6,,"Phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase, catalyzes the fourth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts","cellular amino acid and derivative metabolic process, heterocycle metabolic process",isomerase activity,other,"amino acid and derivative metabolic process, isomerase activity, other",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,32,14,no,,,,, P129,9,A9,P129_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL023C,YKE4,,"Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family",transport,transporter activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, transport, transporter activity",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,18,5.8,no,,,,, P129,10,A10,P129_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL024C,,,Putative protein of unknown function; non-essential gene; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,158,4,2.5,no,,,,, P129,11,A11,P129_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL025C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,36,17.6,no,,,,, P129,12,A12,P129_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL027C,KRE27,EMC5,"Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response, and also shows K1 killer toxin resistance",protein folding,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,24,14.6,no,,,,, P129,13,B1,P129_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL028W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,12,7.3,no,,,,, P129,14,B2,P129_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL029C,,,Putative protein of unknown function; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO),biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,0,0,no,,,,, P129,15,B3,P129_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL032C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,9,4.5,no,,,,, P129,16,B4,P129_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL034C,CAP2,,Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches,"cytoskeleton organization, protein complex biogenesis",protein binding,"cell cortex, site of polarized growth, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,32,12.8,no,,,,, P129,17,B5,P129_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL035C,CKA1,,"Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA2, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases","response to stress, transcription, protein modification process, RNA metabolic process","transferase activity, protein kinase activity","nucleus, nucleolus","RNA metabolic process, anatomical structure morphogenesis, cell cycle, cellular homeostasis, cytoplasm, nucleolus, nucleus, other, protein kinase activity, protein modification process, response to stress, transcription, transferase activity",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,4,1.5,no,,,,, P129,18,B6,P129_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL036W,CST6,SHF1;ACA2,"Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, proposed to be a regulator of oleate responsive genes; involved in utilization of non-optimal carbon sources and chromosome stability","transcription, DNA metabolic process, response to chemical stimulus, protein complex biogenesis, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA metabolic process, RNA metabolic process, nucleus, transcription, transcription regulator activity",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,10,3,no,,,,, P129,19,B7,P129_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL037C,PRM2,,"Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion","conjugation, nucleus organization",molecular_function,membrane,"conjugation, membrane, molecular_function, response to chemical stimulus",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,28,11.9,no,,,,, P129,20,B8,P129_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL039W,TED1,,Conserved phosphoesterase domain-containing protein that acts together with Emp24p/Erv25p in cargo exit from the ER; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO),"transport, vesicle-mediated transport",molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, response to chemical stimulus, transport, vesicle-mediated transport",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,144,14,9.7,no,,,,, P129,21,B9,P129_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL040W,APQ12,,"Protein required for nuclear envelope morphology, nuclear pore complex localization, mRNA export from the nucleus; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism","transport, cellular lipid metabolic process, cellular membrane organization, nucleus organization",molecular_function,"nucleus, endomembrane system, endoplasmic reticulum, cytoplasm","endomembrane system, endoplasmic reticulum, molecular_function, nucleus, transport",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,24,10.5,no,,,,, P129,22,B10,P129_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL041W,GVP36,,"BAR domain-containing protein that localizes to both early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis","vacuole organization, transport, cytoskeleton organization, vesicle-mediated transport, cellular membrane organization",molecular_function,"endomembrane system, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, cytoskeleton organization and biogenesis, endomembrane system, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vesicle-mediated transport",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,30,10.1,no,,,,, P129,23,B11,P129_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL043C,CBR1,CBR5,"Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia",biological_process,oxidoreductase activity,"membrane, membrane fraction, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, membrane fraction, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,18,6.8,no,,,,, P129,24,B12,P129_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL044C,AGE2,SAT2,"ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif","transport, vesicle-mediated transport",enzyme regulator activity,"cytoplasmic membrane-bounded vesicle, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, enzyme regulator activity, transport, vesicle-mediated transport",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,28,11.3,no,,,,, P129,25,C1,P129_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL045W,PIG2,,Putative type-1 protein phosphatase targeting subunit that tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase,"cellular carbohydrate metabolic process, generation of precursor metabolites and energy",enzyme regulator activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, enzyme regulator activity, generation of precursor metabolites and energy",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,22,9.6,no,,,,, P129,26,C2,P129_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL049W,DFG10,,"Protein of unknown function, involved in filamentous growth",pseudohyphal growth,molecular_function,cellular_component,"cellular_component, molecular_function, pseudohyphal growth",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,6,2.3,no,,,,, P129,27,C3,P129_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL050W,PCL7,,"Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated","cellular carbohydrate metabolic process, cell cycle, generation of precursor metabolites and energy",enzyme regulator activity,nucleus,"carbohydrate metabolic process, cell cycle, enzyme regulator activity, generation of precursor metabolites and energy, nucleus, other",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,24,12.8,no,,,,, P129,28,C4,P129_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL053W,RHR2,GPP1,"Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress","response to stress, cellular carbohydrate metabolic process, generation of precursor metabolites and energy",hydrolase activity,"nucleus, cytoplasm","cytoplasm, generation of precursor metabolites and energy, hydrolase activity, nucleus, response to chemical stimulus, response to stress",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,44,17.2,no,,,,, P129,29,C5,P129_C5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P129,30,C6,P129_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL057C,RGI2,,Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,6,2.3,no,,,,, P129,31,C7,P129_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL064W,SEE1,,Probable lysine methyltransferase involved in the dimethylation of eEF1A (Tef1p/Tef2p); sequence similarity to S-adenosylmethionine-dependent methyltransferases of the seven beta-strand family; role in vesicular transport,"transport, vesicle-mediated transport, protein modification process",transferase activity,cytoplasm,"cytoplasm, ribosome biogenesis, transferase activity",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,12,6.2,no,,,,, P129,32,C8,P129_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL065C,FIS1,MDV2,Protein involved in mitochondrial membrane fission and peroxisome abundance; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation,"mitochondrion organization, peroxisome organization",molecular_function,"peroxisome, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, response to chemical stimulus",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,4,1.5,no,,,,, P129,33,C9,P129_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL072W,HOP1,,Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for homologous chromosome synapsis and chiasma formation,"meiosis, signaling process, chromosome organization, cell cycle",DNA binding,"nucleus, chromosome","DNA binding, cell cycle, chromosome, meiosis, nucleus, organelle organization and biogenesis",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,20,14.1,no,,,,, P129,34,C10,P129_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL073C,SPO22,ZIP4,"Meiosis-specific protein essential for chromosome synapsis, involved in completion of nuclear divisions during meiosis; induced early in meiosis","meiosis, chromosome organization, cell cycle",molecular_function,"nucleus, chromosome","cell cycle, chromosome, meiosis, molecular_function, nucleus, organelle organization and biogenesis",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,24,7.5,no,,,,, P129,35,C11,P129_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL076W,SEC28,ANU2,"Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth","transport, vesicle-mediated transport, vesicle organization, cellular membrane organization",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vesicle-mediated transport",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,26,10.2,no,,,,, P129,36,C12,P129_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL077C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)",biological_process,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, response to chemical stimulus",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,18,7.3,no,,,,, P129,37,D1,P129_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL079C,AIR1,,"Zinc knuckle protein, involved in nuclear RNA processing and degradation as a component of the TRAMP complex; stimulates the poly(A) polymerase activity of Pap2p in vitro; functionally redundant with Air2p",RNA metabolic process,"transferase activity, nucleotidyltransferase activity","nucleus, nucleolus","RNA metabolic process, nucleolus, nucleotidyltransferase activity, nucleus, transferase activity, transport",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,166,6,3.6,no,,,,, P129,38,D2,P129_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL084C,SDS3,,"Component of the Rpd3p/Sin3p deacetylase complex required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; cells defective in SDS3 display pleiotropic phenotypes","chromosome organization, transcription, protein modification process, RNA metabolic process",hydrolase activity,"nucleus, chromosome","RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, protein modification process, transcription",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,12,3.8,no,,,,, P129,39,D3,P129_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL086C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,32,11.7,no,,,,, P129,40,D4,P129_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL087C,AIM19,LRC2,"Putative protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays reduced respiratory growth",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,14,6.4,no,,,,, P129,41,D5,P129_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL088C,AVT7,,"Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters",transport,transporter activity,"membrane, vacuole, plasma membrane, cytoplasm","cytoplasm, plasma membrane, transport, transporter activity, vacuole",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,8,3.1,no,,,,, P129,42,D6,P129_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL090W,ICE2,,Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells,other,molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, organelle organization and biogenesis",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,197,6,3,no,,,,, P129,43,D7,P129_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL093C,RSM25,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,14,6.1,no,,,,, P129,44,D8,P129_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL095W,PRK1,PAK1,Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex,"transport, cytoskeleton organization, cytokinesis, protein modification process, vesicle-mediated transport, cellular membrane organization","transferase activity, protein kinase activity","cell cortex, cytoskeleton, site of polarized growth, cytoplasm","cell cortex, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, protein kinase activity, protein modification process, transferase activity, transport, vesicle-mediated transport",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,10,4.2,no,,,,, P129,45,D9,P129_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL096C,,,Putative protein of unknown function; associates with precursors of the 60S ribosomal subunit; predicted to be involved in ribosome biogenesis,biological_process,molecular_function,"nucleus, nucleolus","molecular_function, nucleolus, nucleus, ribosome biogenesis",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,8,4.5,no,,,,, P129,46,D10,P129_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL097W,FYV10,GID9,"Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of FBPase; contains CTLH domain; plays role in anti-apoptosis","cellular carbohydrate metabolic process, cellular protein catabolic process",molecular_function,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, molecular_function, nucleus, other, protein catabolic process",,,09_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,6,3.2,no,,,,, P129,47,D11,P129_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL007W,BLM10,YFL006W,"Proteasome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200",protein complex biogenesis,molecular_function,nucleus,"enzyme regulator activity, nucleus, other, protein catabolic process",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,35,18.6,no,,,,, P129,48,D12,P129_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL011W,HXT10,,"Putative hexose transporter, expressed at low levels and expression is repressed by glucose",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, plasma membrane, transport, transporter activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,232,18,7.8,no,,,,, P129,49,E1,P129_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL015C,,,Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,12,5.8,no,,,,, P129,50,E2,P129_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL018C,LPD1,HPD1,"Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes",cellular amino acid and derivative metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, other, oxidoreductase activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,28,10,no,,,,, P129,51,E3,P129_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL020C,PAU5,,Member of the seripauperin multigene family encoded mainly in subtelomeric regions; induced during alcoholic fermentation; induced by low temperature and also by anaerobic conditions; negatively regulated by oxygen and repressed by heme,biological_process,molecular_function,membrane fraction,"biological_process, membrane fraction, molecular_function, other",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,28,16.1,no,,,,, P129,52,E4,P129_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL021W,GAT1,MEP80;NIL1,Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p,"transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, other, transcription, transcription regulator activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,20,6.1,no,,,,, P129,53,E5,P129_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL023W,BUD27,URI1,Unconventional prefoldin protein involved in translation initiation; mutants have inappropriate expression of nutrient sensitive genes due to translational derepression of Gcn4p transcription factor; diploid mutants show random budding,translation,molecular_function,"ribosome, cytoplasm","DNA metabolic process, anatomical structure morphogenesis, cytokinesis, cytoplasm, molecular_function, transposition",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,48,22.9,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P129,54,E6,P129_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL025C,BST1,PER17,"GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules","transport, vesicle organization, vesicle-mediated transport, cellular lipid metabolic process, cellular protein catabolic process",hydrolase activity,"membrane, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, lipid metabolic process, membrane, organelle organization and biogenesis, other, protein catabolic process, transport, vesicle-mediated transport",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,28,11,no,,,,, P129,55,E7,P129_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL026W,STE2,,Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells,"signaling process, response to chemical stimulus, protein complex biogenesis, conjugation",signal transducer activity,"membrane fraction, membrane, plasma membrane","anatomical structure morphogenesis, conjugation, membrane, membrane fraction, other, plasma membrane, response to chemical stimulus, signal transducer activity, signal transduction",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,24,9.2,no,,,,, P129,56,E8,P129_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL027C,GYP8,,"GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport","transport, vesicle-mediated transport",enzyme regulator activity,other,"enzyme regulator activity, other, vesicle-mediated transport",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,8,4.3,no,,,,, P129,57,E9,P129_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL028C,CAF16,,Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator,"transcription, RNA metabolic process",hydrolase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, hydrolase activity, nucleus, transcription",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,30,9.1,no,,,,, P129,58,E10,P129_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL030W,AGX1,alanine:glyoxylate aminotransferase,"Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases",cellular amino acid and derivative metabolic process,transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, transferase activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,13,7.1,no,,,,, P129,59,E11,P129_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL031W,HAC1,IRE15;ERN4,"Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis","response to stress, cellular lipid metabolic process, transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, lipid metabolic process, nucleus, response to chemical stimulus, response to stress, signal transduction, transcription, transcription regulator activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,18,6.1,no,,,,, P129,60,E12,P129_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL032W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene HAC1/YFL031W; YFL032W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,34,10.2,no,,,,, P129,61,F1,P129_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL034W,,,"Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk",biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,20,9.3,no,,,,, P129,62,F2,P129_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL034C-A,RPL22B,rp4;l1c;YL31;L22B;YFL035C-B,"Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,8,4.5,no,,,,, P129,63,F3,P129_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL036W,RPO41,,Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition,"mitochondrion organization, transcription, generation of precursor metabolites and energy, cellular respiration, RNA metabolic process","transferase activity, nucleotidyltransferase activity","mitochondrion, cytoplasm","RNA metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, nucleotidyltransferase activity, organelle organization and biogenesis, transcription, transferase activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,48,14.4,no,,,,, P129,64,F4,P129_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL040W,,,"Putative transporter, member of the sugar porter family; YFL040W is not an essential gene",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,48,16.3,no,,,,, P129,65,F5,P129_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL041W,FET5,,"Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport",transport,oxidoreductase activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, oxidoreductase activity, transport, vacuole",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,28,10.6,no,,,,, P129,66,F6,P129_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL042C,,YFL043C,Putative protein of unknown function; YFL042C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,34,11.3,no,,,,, P129,67,F7,P129_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL044C,OTU1,YOD1,Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family,"transcription, protein modification process","peptidase activity, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, peptidase activity, protein modification process, transcription",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,28,11.8,no,,,,, P129,68,F8,P129_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL046W,FMP32,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,28,8.7,no,,,,, P129,69,F9,P129_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL047W,RGD2,,GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p,signaling process,enzyme regulator activity,"cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoplasm, enzyme regulator activity, signal transduction, site of polarized growth",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,42,13.5,no,,,,, P129,70,F10,P129_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL048C,EMP47,,"Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport","transport, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, transport, vesicle-mediated transport",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,32,10.7,no,,,,, P129,71,F11,P129_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL049W,SWP82,,Member of the SWI/SNF chromatin remodeling complex in which it plays an as yet unidentified role; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p,"chromosome organization, transcription, cellular protein catabolic process",transcription regulator activity,nucleus,"nucleus, organelle organization and biogenesis, protein catabolic process, transcription, transcription regulator activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,32,11.8,no,,,,, P129,72,F12,P129_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL050C,ALR2,,Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions; plays a role in regulating Ty1 transposition,transport,transporter activity,"membrane, plasma membrane","DNA metabolic process, plasma membrane, transport, transporter activity, transposition",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,26,11.8,no,,,,, P129,73,G1,P129_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR379C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR378W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,14,5.6,no,,,,, P129,74,G2,P129_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL051C,,,Putative protein of unknown function; YFL051C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,7,3.7,no,,,,, P129,75,G3,P129_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL052W,,,"Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity",biological_process,DNA binding,cellular_component,"DNA binding, biological_process, cellular_component",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,36,11.8,no,,,,, P129,76,G4,P129_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL053W,DAK2,,"Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation","response to stress, cellular carbohydrate metabolic process",transferase activity,cellular_component,"cellular_component, other, response to stress, transferase activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,36,19.8,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P129,77,G5,P129_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL054C,,,Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol,transport,transporter activity,membrane,"membrane, transport, transporter activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,34,10.3,no,,,,, P129,78,G6,P129_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL055W,AGP3,,"Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition",transport,transporter activity,"membrane, plasma membrane","DNA metabolic process, plasma membrane, transport, transporter activity, transposition",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,24,11.2,no,,,,, P129,79,G7,P129_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL056C,AAD6,,"Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response; expression induced in cells treated with the mycotoxin patulin",other,oxidoreductase activity,cellular_component,"cellular_component, other, oxidoreductase activity, response to chemical stimulus",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,24,8.9,no,,,,, P129,80,G8,P129_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR001W,LOC1,,Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles,"ribosome biogenesis, RNA metabolic process",RNA binding,"nucleus, nucleolus","RNA binding, cytoplasm, nucleolus, nucleus, organelle organization and biogenesis, other, ribosome biogenesis",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,285,2,0.7,no,,,,, P129,81,G9,P129_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR006W,,,Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,32,10.1,no,,,,, P129,82,G10,P129_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR007W,YFH7,AIM12,Putative kinase with similarity to the phosphoribulokinase/uridine kinase/bacterial pantothenate kinase (PRK/URK/PANK) subfamily of P-loop kinases,other,"transferase activity, hydrolase activity",cellular_component,"cellular_component, hydrolase activity, other, transferase activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,54,21.4,no,,,,, P129,83,G11,P129_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR008W,FAR7,,"Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p","conjugation, cell cycle, response to chemical stimulus",molecular_function,cellular_component,"cell cycle, cellular_component, conjugation, molecular_function, response to chemical stimulus",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,20,6,no,,,,, P129,84,G12,P129_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR009W,GCN20,,"Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA",translation,hydrolase activity,"ribosome, cytoplasm","cytoplasm, hydrolase activity, ribosome, translation",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,38,11.2,no,,,,, P129,85,H1,P129_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR010W,UBP6,,"Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; works in opposition to polyubiquitin elongation activity of Hul5p",protein modification process,"peptidase activity, hydrolase activity",other,"hydrolase activity, other, peptidase activity, protein modification process",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,8,4.1,no,,,,, P129,86,H2,P129_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR012W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,30,13.6,no,,,,, P129,87,H3,P129_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P129,88,H4,P129_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR014C,CMK1,,"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II","signaling process, protein modification process","transferase activity, protein kinase activity",cytoplasm,"cytoplasm, protein kinase activity, protein modification process, signal transduction, transferase activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,16,5.8,no,,,,, P129,89,H5,P129_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR015C,GSY1,,"Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,"mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, transferase activity",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,40,14.2,no,,,,, P129,90,H6,P129_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR016C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and bud; interacts with Spa2p; YFL016C is not an essential gene,biological_process,molecular_function,"cellular bud, cytoplasm","biological_process, cellular bud, cytoplasm, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,11,6.3,no,,,,, P129,91,H7,P129_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR017C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YFR017C is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,36,11.5,no,,,,, P129,92,H8,P129_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR018C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,14,7.7,no,,,,, P129,93,H9,P129_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR020W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,7,3.6,no,,,,, P129,94,H10,P129_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR021W,ATG18,SVP1;AUT10;CVT18;NMR1,"Phosphoinositide binding protein required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein","transport, peroxisome organization, response to stress, vesicle-mediated transport, cellular membrane organization",lipid binding,"vacuole, membrane, cytoplasm","cytoplasm, lipid binding, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein modification process, response to stress, transport, vacuole, vesicle-mediated transport",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,28,15.1,no,,,,, P129,95,H11,P129_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR022W,ROG3,ART7,Protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; has similarity to Rod1p; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; proposed to regulate the endocytosis of plasma membrane proteins,"transport, vesicle-mediated transport, cellular membrane organization",protein binding,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,26,8.2,no,,,,, P129,96,H12,P129_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR023W,PES4,,"Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,22,8.6,no,,,,, P130,1,A1,P130_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR024C-A,LSB3,YFR024C,"Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization",other,molecular_function,"cellular bud, site of polarized growth, mitochondrion, cytoplasm","cellular bud, cytoplasm, cytoskeleton organization and biogenesis, mitochondrion, molecular_function, organelle organization and biogenesis, site of polarized growth",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,40,12.2,no,,,,, P130,2,A2,P130_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR026C,ULI1,,Putative protein of unknown function involved in and induced by the endoplasmic reticulum unfolded protein response,"response to stress, response to chemical stimulus",molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,10,3.4,no,,,,, P130,3,A3,P130_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR031C-A,RPL2A,rp8;YL6;L5A;L2A;RPL5B,"Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,06_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,5,2.6,no,,,,, P130,4,A4,P130_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR256W,GND2,,"6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone","cofactor metabolic process, cellular carbohydrate metabolic process",oxidoreductase activity,"membrane fraction, cytoplasm","carbohydrate metabolic process, cofactor metabolic process, cytoplasm, oxidoreductase activity, vitamin metabolic process",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,6,3,no,,,,, P130,5,A5,P130_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR259C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF TNA1/YGR260W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,10,4.5,no,,,,, P130,6,A6,P130_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR260W,TNA1,,"High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","membrane, mitochondrion, plasma membrane, transport, transporter activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,10,3.3,no,,,,, P130,7,A7,P130_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR261C,APL6,YKS5,Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools,"transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasm","cytoplasm, membrane, molecular_function, transport, vesicle-mediated transport",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,11,5,no,,,,, P130,8,A8,P130_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR263C,SAY1,,Sterol deacetylase; component of the sterol acetylation/deacetylation cycle along with Atf2p; integral membrane protein with active site in the ER lumen; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum,"cellular lipid metabolic process, response to chemical stimulus",hydrolase activity,"membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, hydrolase activity, lipid metabolic process, membrane, response to chemical stimulus",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,6,2.2,no,,,,, P130,9,A9,P130_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR266W,,,"Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, plasma membrane, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, plasma membrane",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,8,2.5,no,,,,, P130,10,A10,P130_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR268C,HUA1,,Cytoplasmic protein containing a zinc finger domain with sequence similarity to that of Type I J-proteins; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly,biological_process,molecular_function,cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,19,11.1,no,,,,, P130,11,A11,P130_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR269W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF HUA1/YGR268C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,20,7.4,no,,,,, P130,12,A12,P130_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR270W,YTA7,,"Protein that localizes to chromatin and has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; potentially phosphorylated by Cdc28p","cellular lipid metabolic process, transcription, RNA metabolic process",hydrolase activity,"nucleus, membrane, endomembrane system, endoplasmic reticulum, cytoplasm","hydrolase activity, nucleus, protein catabolic process",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,8,2.9,no,,,,, P130,13,B1,P130_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR275W,RTT102,,"Component of both the SWI/SNF and RSC chromatin remodeling complexes, suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition","chromosome organization, transcription, chromosome segregation, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, other, transcription",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,13,5.9,no,,,,, P130,14,B2,P130_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR279C,SCW4,,Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating,conjugation,hydrolase activity,"cell wall, extracellular region","cell wall, conjugation, hydrolase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,8,2.6,no,,,,, P130,15,B3,P130_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR281W,YOR1,YRS1,"Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter mediates export of many different organic anions including oligomycin; similar to human cystic fibrosis transmembrane receptor (CFTR)","transport, response to chemical stimulus","transporter activity, hydrolase activity","membrane, membrane fraction, plasma membrane","hydrolase activity, membrane fraction, plasma membrane, response to chemical stimulus, transport, transporter activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,269,4,1.5,no,,,,, P130,16,B4,P130_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR282C,BGL2,,"Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance",fungal-type cell wall organization,"transferase activity, hydrolase activity",cell wall,"cell wall, cell wall organization and biogenesis, hydrolase activity, transferase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,10,3.9,no,,,,, P130,17,B5,P130_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR283C,,,"Protein of unknown function; may interact with ribosomes, based on co-purification experiments; predicted to be involved in ribosome biogenesis; null mutant is resistant to fluconazole; GFP-fusion protein localizes to the nucleolus",biological_process,molecular_function,"nucleus, nucleolus, ribosome, cytoplasm","molecular_function, nucleolus, ribosome, ribosome biogenesis",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,10,6.3,no,,,,, P130,18,B6,P130_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR284C,ERV29,,"Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo","transport, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, transport, vesicle-mediated transport",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,30,8.9,no,,,,, P130,19,B7,P130_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR285C,ZUO1,zuotin,"Ribosome-associated chaperone, functions in ribosome biogenesis and, in partnership with Ssz1p and SSb1/2, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p","transport, translation, protein folding, ribosome biogenesis, RNA metabolic process",protein binding,"nucleus, ribosome, mitochondrion, nucleolus, cytoplasm","cytoplasm, mitochondrion, protein binding, protein folding, ribosome, translation",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,4,2.2,no,,,,, P130,20,B8,P130_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR286C,BIO2,,"Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant","cofactor metabolic process, vitamin metabolic process, heterocycle metabolic process",transferase activity,"mitochondrion, cytoplasm","cofactor metabolic process, heterocycle metabolic process, mitochondrion, transferase activity, vitamin metabolic process",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,6,3.5,no,,,,, P130,21,B9,P130_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR287C,IMA1,,"Major isomaltase (alpha-1,6-glucosidase) required for isomaltose utilization; has specificity for isomaltose, palatinose, and methyl-alpha-glucoside; member of the IMA isomaltase family",cellular carbohydrate metabolic process,hydrolase activity,"ribosome, mitochondrion, cytoplasm","biological_process, hydrolase activity, mitochondrion, ribosome",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,8,2.5,no,,,,, P130,22,B10,P130_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR288W,MAL13,MALR,"MAL-activator protein, part of complex locus MAL1; nonfunctional in genomic reference strain S288C","cellular carbohydrate metabolic process, transcription, RNA metabolic process",other,nucleus,"DNA binding, RNA metabolic process, carbohydrate metabolic process, nucleus, transcription, transcription regulator activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,6,3.3,no,,,,, P130,23,B11,P130_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR290W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; putative HLH protein; partially overlaps the verified ORF MAL11/YGR289C (a high-affinity maltose transporter)",biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,44,16.2,no,,,,, P130,24,B12,P130_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR021W-A,ECM12,,Non-essential protein of unknown function,fungal-type cell wall organization,molecular_function,cellular_component,"cell wall organization and biogenesis, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,8,2.6,no,,,,, P130,25,C1,P130_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR039C-A,VMA10,YHR039BC;YHR039C-B,"Subunit G of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","carbohydrate metabolic process, cellular homeostasis, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, membrane, transporter activity, vacuole",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,13,7.4,no,,,,, P130,26,C2,P130_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR079C-A,SAE3,YHR079BC;YHR079C-B,"Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p","response to stress, meiosis, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleus, response to stress",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,5,2.9,no,,,,, P130,27,C3,P130_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL009C-A,EST3,,"Component of the telomerase holoenzyme, involved in telomere replication","chromosome organization, DNA metabolic process","DNA binding, helicase activity, hydrolase activity","nucleus, chromosome","DNA metabolic process, chromosome, nucleotidyltransferase activity, nucleus, organelle organization and biogenesis, transferase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,232,4,1.7,no,,,,, P130,28,C4,P130_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR017C,MET28,,"Basic leucine zipper (bZIP) transcriptional activator in the Cbf1p-Met4p-Met28p complex, participates in the regulation of sulfur metabolism","transcription, cellular amino acid and derivative metabolic process, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, amino acid and derivative metabolic process, nucleus, other, response to chemical stimulus, transcription, transcription regulator activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,12,5.5,no,,,,, P130,29,C5,P130_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR018W,YAP5,,Basic leucine zipper (bZIP) transcription factor,"transcription, RNA metabolic process",transcription regulator activity,"nucleus, chromosome","RNA metabolic process, cell cycle, nucleus, transcription, transcription regulator activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,16,5.8,no,,,,, P130,30,C6,P130_C6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P130,31,C7,P130_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR019C,MUC1,STA4;FLO11,"GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)",pseudohyphal growth,molecular_function,"cellular bud, membrane, site of polarized growth, plasma membrane","molecular_function, other, plasma membrane, pseudohyphal growth",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,28,9.3,no,,,,, P130,32,C8,P130_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR020C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,24,9.3,no,,,,, P130,33,C9,P130_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR020W-A,,YIR020W-B,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,8,4.5,no,,,,, P130,34,C10,P130_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR021W,MRS1,PET157,"Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA",RNA metabolic process,RNA binding,"mitochondrion, cytoplasm","RNA binding, RNA metabolic process, mitochondrion",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,1,0.5,no,,,,, P130,35,C11,P130_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR024C,,GIF1,"Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; interacts with Arh1p, a mitochondrial oxidoreductase; deletion mutant has a respiratory growth defect",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,30,9.4,no,,,,, P130,36,C12,P130_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR025W,MND2,,Subunit of the anaphase-promoting complex (APC); necessary for maintaining sister chromatid cohesion in prophase I of meiosis by inhibiting premature ubiquitination and subsequent degradation of substrates by the APC(Ama1) ubiquitin ligase,"protein modification process, chromosome segregation, meiosis, chromosome organization, cell cycle, DNA metabolic process, cellular protein catabolic process",molecular_function,nucleus,"DNA metabolic process, cell cycle, meiosis, molecular_function, nucleus, organelle organization and biogenesis, protein catabolic process, protein modification process",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,6,2.9,no,,,,, P130,37,D1,P130_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR026C,YVH1,,"Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; mutants are defective in 60S ribosome assembly; member of the dual-specificity family of protein phosphatases","signaling process, protein modification process, meiosis, sporulation resulting in formation of a cellular spore, ribosome biogenesis, cellular component morphogenesis, cell cycle","hydrolase activity, phosphoprotein phosphatase activity","nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, meiosis, phosphoprotein phosphatase activity, ribosome biogenesis, sporulation",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,18,6.7,no,,,,, P130,38,D2,P130_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR027C,DAL1,,"Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression",heterocycle metabolic process,hydrolase activity,cellular_component,"heterocycle metabolic process, hydrolase activity, other",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,150,2,1.3,no,,,,, P130,39,D3,P130_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR028W,DAL4,,"Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation","transport, heterocycle metabolic process",transporter activity,membrane,"heterocycle metabolic process, membrane, transport, transporter activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,2,0.7,no,,,,, P130,40,D4,P130_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR029W,DAL2,ALC1,"Allantoicase, converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation",heterocycle metabolic process,hydrolase activity,cellular_component,"cellular_component, heterocycle metabolic process, hydrolase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,14,5.3,no,,,,, P130,41,D5,P130_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR031C,DAL7,MSL2;MLS2,"Malate synthase, role in allantoin degradation unknown; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation",heterocycle metabolic process,transferase activity,cellular_component,"cellular_component, heterocycle metabolic process, transferase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,11,6.3,no,,,,, P130,42,D6,P130_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR033W,MGA2,,"ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting","response to stress, cellular lipid metabolic process, transcription, RNA metabolic process",transcription regulator activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","RNA metabolic process, cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, response to stress, transcription, transcription regulator activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,12,4.3,no,,,,, P130,43,D7,P130_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR034C,LYS1,,"Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway",cellular amino acid and derivative metabolic process,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, oxidoreductase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,4,1.4,no,,,,, P130,44,D8,P130_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR035C,,,Putative cytoplasmic protein of unknown function,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,18,7.5,no,,,,, P130,45,D9,P130_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR036C,IRC24,,Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52p foci,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,62,18.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P130,46,D10,P130_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR037W,HYR1,ORP1;GPX3,Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor,"response to stress, response to chemical stimulus",oxidoreductase activity,other,"other, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,16,4.9,no,,,,, P130,47,D11,P130_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR038C,GTT1,,"ER associated glutathione S-transferase capable of homodimerization; expression induced during the diauxic shift and throughout stationary phase; functional overlap with Gtt2p, Grx1p, and Grx2p","cofactor metabolic process, cellular amino acid and derivative metabolic process","transferase activity, oxidoreductase activity","membrane fraction, mitochondrion, membrane, mitochondrial envelope, endoplasmic reticulum, cytoplasm","cofactor metabolic process, cytoplasm, endoplasmic reticulum, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transferase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,24,14,no,,,,, P130,48,D12,P130_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR039C,YPS6,,"Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance",fungal-type cell wall organization,"peptidase activity, hydrolase activity",cell wall,"biological_process, cell wall, hydrolase activity, peptidase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,4,2.3,no,,,,, P130,49,E1,P130_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR042C,,,Putative protein of unknown function; YIR042C is a non-essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,457,7,1.5,no,,,,, P130,50,E2,P130_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL033W-A,,,Putative protein of unknown function; similar to uncharacterized proteins from other fungi,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,24,7.2,no,,,,, P130,51,E3,P130_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL162C-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,10,3.8,no,,,,, P130,52,E4,P130_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR035W-A,DID2,VPL30;VPS46;CHM1;FTI1,Class E protein of the vacuolar protein-sorting (Vps) pathway; binds Vps4p and directs it to dissociate ESCRT-III complexes; forms a functional and physical complex with Ist1p; human ortholog may be altered in breast tumors,"transport, vesicle-mediated transport",molecular_function,cytoplasm,"cytoplasm, molecular_function, transport, vesicle-mediated transport",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,10,4.6,no,,,,, P130,53,E5,P130_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR066C,CCP1,,"Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress","response to stress, response to chemical stimulus",oxidoreductase activity,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, mitochondrial envelope, mitochondrion, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,9,5.3,no,,,,, P130,54,E6,P130_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR067W,GPT2,GAT1,Glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase located in lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone in lipid biosynthesis,cellular lipid metabolic process,transferase activity,"membrane fraction, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, lipid metabolic process, transferase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,20,9.7,no,,,,, P130,55,E7,P130_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR069W,MET1,MET20,"S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis","cofactor metabolic process, cellular amino acid and derivative metabolic process, heterocycle metabolic process",transferase activity,other,"amino acid and derivative metabolic process, cofactor metabolic process, heterocycle metabolic process, other, transferase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,44,13.2,no,,,,, P130,56,E8,P130_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR070W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,20,10.9,no,,,,, P130,57,E9,P130_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR072C,SIS2,HAL3,"Negative regulatory subunit of protein phosphatase 1 Ppz1p and also a subunit of the phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex, which catalyzes the third step of coenzyme A biosynthesis","response to stress, cofactor metabolic process, cell cycle","lyase activity, enzyme regulator activity","nucleus, cytoplasm","cell cycle, cofactor metabolic process, cytoplasm, enzyme regulator activity, lyase activity, nucleus, response to stress",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,16,7.8,no,,,,, P130,58,E10,P130_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR073C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,36,11.3,no,,,,, P130,59,E11,P130_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR074W,AIM29,,Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; YKR074W is not an essential gene; null mutant displays elevated frequency of mitochondrial genome loss,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,13,7.5,no,,,,, P130,60,E12,P130_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR075C,,,Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,236,7,3,no,,,,, P130,61,F1,P130_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR076W,ECM4,GTO2,Omega class glutathione transferase; not essential; similar to Ygr154cp; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,"fungal-type cell wall organization, cofactor metabolic process, cellular amino acid and derivative metabolic process",transferase activity,cytoplasm,"cell wall organization and biogenesis, cofactor metabolic process, cytoplasm, response to chemical stimulus, transferase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,19,10.6,no,,,,, P130,62,F2,P130_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR077W,MSA2,,"Putative transcriptional activator, that interacts with G1-specific transcription factor, MBF and G1-specific promoters; ortholog of Msa2p, an MBF and SBF activator that regulates G1-specific transcription and cell cycle initiation","transcription, cell cycle, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cell cycle, cytoplasm, molecular_function, nucleus, transcription",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,16,7.4,no,,,,, P130,63,F3,P130_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR078W,,,"Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)",biological_process,lipid binding,cytoplasm,"cytoplasm, lipid binding, transport, transporter activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,18,5.7,no,,,,, P130,64,F4,P130_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR080W,MTD1,,"NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline","cofactor metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",oxidoreductase activity,cytoplasm,"aromatic compound metabolic process, cofactor metabolic process, cytoplasm, heterocycle metabolic process, other, oxidoreductase activity",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,7,3,no,,,,, P130,65,F5,P130_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR082W,NUP133,RAT3,"Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p","transport, ribosome biogenesis, nucleus organization",structural molecule activity,"nucleus, membrane, endomembrane system","endomembrane system, membrane, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, other, structural molecule activity, transport",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,444,127,28.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P130,66,F6,P130_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR084C,HBS1,,"GTP binding protein with sequence similarity to the elongation factor class of G proteins, EF-1alpha and Sup35p; associates with Dom34p, and shares a similar genetic relationship with genes that encode ribosomal protein components","translation, RNA metabolic process",molecular_function,cytoplasm,"cytoplasm, molecular_function, translation",,,00_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,20,10.6,no,,,,, P130,67,F7,P130_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR062C,ARG7,ECM40,"Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine","fungal-type cell wall organization, cellular amino acid and derivative metabolic process",transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cell wall organization and biogenesis, cytoplasm, mitochondrion, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,4,1.9,no,,,,, P130,68,F8,P130_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR063W,RIM9,,"Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalI; putative membrane protein",sporulation resulting in formation of a cellular spore,molecular_function,cellular_component,"cellular_component, molecular_function, sporulation",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,62,20.1,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P130,69,F9,P130_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR064W,AEP1,NCA1,Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase,translation,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, translation",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,330,36,10.9,no,,,,, P130,70,F10,P130_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR065W,KAR5,FIG3,"Protein required for nuclear membrane fusion during karyogamy, localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; expression of the gene is regulated by pheromone","conjugation, nucleus organization",molecular_function,"endomembrane system, mitochondrion, membrane, endoplasmic reticulum, cytoplasm","conjugation, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, mitochondrion, molecular_function, nuclear organization and biogenesis, organelle organization and biogenesis",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,22,7.5,no,,,,, P130,71,F11,P130_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR066W,SOV1,,Mitochondrial protein of unknown function,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,10,4.5,no,,,,, P130,72,F12,P130_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR067C,UBX4,CUI1,UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p,"sporulation resulting in formation of a cellular spore, cellular protein catabolic process",molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, protein catabolic process, sporulation",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,22,12,no,,,,, P130,73,G1,P130_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR068W,AVO2,,"Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth","fungal-type cell wall organization, signaling process, cytoskeleton organization",molecular_function,cytoplasm,"cell wall organization and biogenesis, cytoplasm, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis, other, signal transduction",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,46,18.3,no,,,,, P130,74,G2,P130_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR069W,NAT4,NAA40,"N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A","chromosome organization, protein modification process",transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, organelle organization and biogenesis, protein modification process, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,48,14.3,no,,,,, P130,75,G3,P130_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR070W,MOT3,ROX7,"Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes","transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, nucleus, transcription, transcription regulator activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,32,13.9,no,,,,, P130,76,G4,P130_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR071C,TVP18,,"Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, vesicle-mediated transport",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,9,4.9,no,,,,, P130,77,G5,P130_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR072W,ABF2,,"Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation",mitochondrion organization,DNA binding,"chromosome, mitochondrion, cytoplasm","DNA binding, chromosome, cytoplasm, mitochondrion, organelle organization and biogenesis",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,238,13,5.5,no,,,,, P130,78,G6,P130_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR073C,IRC21,,Putative protein of unknown function; proposed to be involved in resistance to carboplatin and cisplatin; shares similarity to a human cytochrome oxidoreductase; null mutant displays increased levels of spontaneous Rad52p foci,response to chemical stimulus,molecular_function,cytoplasm,"cytoplasm, molecular_function, response to chemical stimulus",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,27,15.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P130,79,G7,P130_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR075C-A,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RCO1/YMR075W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,28,10.3,no,,,,, P130,80,G8,P130_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR075W,RCO1,,Essential subunit of the histone deacetylase Rpd3S complex; interacts with Eaf3p,"chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process",hydrolase activity,"nucleus, chromosome","hydrolase activity, nucleus, organelle organization and biogenesis, protein modification process",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,50,20.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P130,81,G9,P130_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR077C,VPS20,VPL10;VPT20;CHM6,"Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes","transport, vesicle-mediated transport, vesicle organization, cellular protein catabolic process, cellular membrane organization",protein binding,"membrane, cytoplasm","cytoplasm, membrane, protein binding, protein catabolic process, transport, vesicle-mediated transport",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,326,24,7.4,no,,,,, P130,82,G10,P130_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR078C,CTF18,CHL12,Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint,"chromosome segregation, response to stress, chromosome organization, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome, mitochondrion, cytoplasm","cell cycle, chromosome, mitochondrion, molecular_function, nucleus, organelle organization and biogenesis",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,26,14.1,no,,,,, P130,83,G11,P130_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR080C,NAM7,SUP113;UPF1;MOF4;IFS2,ATP-dependent RNA helicase of the SFI superfamily involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; involved in telomere maintenance,"translation, transcription, protein modification process, RNA metabolic process","helicase activity, hydrolase activity",cytoplasm,"RNA metabolic process, cytoplasm, helicase activity, hydrolase activity, organelle organization and biogenesis, other, protein modification process, transcription, translation",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,9,4.7,no,,,,, P130,84,G12,P130_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR081C,ISF1,MBR3,"Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant","generation of precursor metabolites and energy, cellular respiration",molecular_function,cellular_component,"cellular respiration, cellular_component, generation of precursor metabolites and energy, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,20,9,no,,,,, P130,85,H1,P130_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR082C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,26,13.4,no,,,,, P130,86,H2,P130_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR083W,ADH3,,Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production,"cofactor metabolic process, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, other, oxidoreductase activity, vitamin metabolic process",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,8,2.5,no,,,,, P130,87,H3,P130_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P130,88,H4,P130_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR084W,,,Putative protein of unknown function; YMR084W and adjacent ORF YMR085W are merged in related strains,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,8,4.5,no,,,,, P130,89,H5,P130_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR085W,,,Putative protein of unknown function; YMR085W and adjacent ORF YMR084W are merged in related strains,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,10,5.2,no,,,,, P130,90,H6,P130_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR086C-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,16,8.6,no,,,,, P130,91,H7,P130_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR086W,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; GFP-fusion protein localizes to the cell periphery; possible component of the eisosome; expression is repressed by cAMP",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,17,8.7,no,,,,, P130,92,H8,P130_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR087W,,,Putative ADP-ribose-1''-monophosphatase that converts ADP-ribose-1''-monophosphate to ADP-ribose; may have a role in tRNA splicing; contains an A1pp domain,RNA metabolic process,hydrolase activity,cellular_component,"RNA metabolic process, cellular_component, hydrolase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,12,6.6,no,,,,, P130,93,H9,P130_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR088C,VBA1,,Permease of basic amino acids in the vacuolar membrane,transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,13,6.9,no,,,,, P130,94,H10,P130_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR089C,YTA12,RCA1,"Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes","transport, mitochondrion organization, protein complex biogenesis","peptidase activity, hydrolase activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, peptidase activity, protein modification process, transport",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,224,11,4.9,no,,,,, P130,95,H11,P130_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR090W,,,"Putative protein of unknown function with similarity to DTDP-glucose 4,6-dehydratases; GFP-fusion protein localizes to the cytoplasm; up-regulated in response to the fungicide mancozeb; not essential for viability",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,14,6.2,no,,,,, P130,96,H12,P130_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR091C,NPL6,RSC7,"Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions; involved in nuclear protein import and maintenance of proper telomere length","transport, response to stress, chromosome organization, transcription, RNA metabolic process",hydrolase activity,nucleus,"RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, response to stress, transcription, transport",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,246,2,0.8,no,,,,, P131,1,A1,P131_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR092C,AIP1,,"Actin cortical patch component, interacts with the actin depolymerizing factor cofilin; required to restrict cofilin localization to cortical patches; contains WD repeats","response to stress, cytoskeleton organization",protein binding,"nucleus, cell cortex, site of polarized growth, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, nucleus, organelle organization and biogenesis, protein binding, response to stress",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,14,8,no,,,,, P131,2,A2,P131_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR070W,PDR18,,"Putative transporter of the ATP-binding cassette (ABC) family, implicated in pleiotropic drug resistance; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",transport,"transporter activity, hydrolase activity","membrane, mitochondrion, cytoplasm","hydrolase activity, membrane, mitochondrion, transport, transporter activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,0,0,no,,,,, P131,3,A3,P131_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR071C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,1,0.5,no,,,,, P131,4,A4,P131_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR072W,HXT17,,"Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,2,0.6,no,,,,, P131,5,A5,P131_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR073C,,,Putative mannitol dehydrogenase,biological_process,oxidoreductase activity,cellular_component,"biological_process, cellular_component, oxidoreductase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,2,1,no,,,,, P131,6,A6,P131_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR074C,AIF1,CPD1,"Mitochondrial cell death effector that translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase","response to stress, response to chemical stimulus",oxidoreductase activity,"nucleus, membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, nucleus, other, oxidoreductase activity, plasma membrane, response to chemical stimulus, response to stress",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,321,0,0,no,,,,, P131,7,A7,P131_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR075W,COS10,,"Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins","transport, vesicle-mediated transport, cellular membrane organization",molecular_function,"nucleus, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane organization and biogenesis, molecular_function, nucleus, transport, vesicle-mediated transport",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P131,8,A8,P131_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL013W-A,,YOL013W-B,Putative protein of unknown function; identified by SAGE,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,14,4.2,no,,,,, P131,9,A9,P131_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL086C,ADH1,ADC1,"Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway","cofactor metabolic process, cellular carbohydrate metabolic process, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,"membrane fraction, cytoplasm","amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, oxidoreductase activity, vitamin metabolic process",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,205,1,0.5,no,,,,, P131,10,A10,P131_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL087C,,,"Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,22,11.2,no,,,,, P131,11,A11,P131_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL088C,MPD2,,"Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity; overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions; undergoes oxidation by Ero1p",protein folding,"isomerase activity, oxidoreductase activity","endoplasmic reticulum, cytoplasm","endoplasmic reticulum, isomerase activity, oxidoreductase activity, protein folding",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,12,5.1,no,,,,, P131,12,A12,P131_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL089C,HAL9,,Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression,"response to stress, transcription, protein complex biogenesis, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, nucleus, response to stress, transcription, transcription regulator activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P131,13,B1,P131_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL090W,MSH2,PMS5,Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP,"transcription, response to stress, meiosis, cell cycle, DNA metabolic process, RNA metabolic process","hydrolase activity, DNA binding","nucleus, chromosome","DNA binding, DNA metabolic process, RNA metabolic process, cell cycle, chromosome, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, other, response to stress, transcription",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,44,15.3,no,,,,, P131,14,B2,P131_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL091W,SPO21,MPC70,"Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation","meiosis, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cell cycle",structural molecule activity,"cytoskeleton, microtubule organizing center, cytoplasm","cell wall organization and biogenesis, cytoplasm, cytoskeleton, meiosis, microtubule organizing center, sporulation, structural molecule activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,24,7.7,no,,,,, P131,15,B3,P131_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL092W,,,Putative protein of unknown function; predicted to contain six transmembrane domains and is 58% similar to the uncharacterized ORF YBR147W,biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,24,10.3,no,,,,, P131,16,B4,P131_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL093W,TRM10,,"tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs",RNA metabolic process,transferase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,12,6.7,no,,,,, P131,17,B5,P131_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL095C,HMI1,,"Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription; has homology to E. coli helicase uvrD","mitochondrion organization, DNA metabolic process","helicase activity, hydrolase activity","mitochondrion, cytoplasm","DNA metabolic process, cytoplasm, helicase activity, hydrolase activity, mitochondrion, organelle organization and biogenesis",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,4,1.8,no,,,,, P131,18,B6,P131_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL096C,COQ3,,"O-methyltransferase, catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex; phosphoprotein",cofactor metabolic process,transferase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,2,1.2,no,,,,, P131,19,B7,P131_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL098C,,,Putative metalloprotease,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,6,2.2,no,,,,, P131,20,B8,P131_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL099C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene PKH2/YOL100W; may interact with ribosomes",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,12,6.2,no,,,,, P131,21,B9,P131_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL100W,PKH2,,"Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p","signaling process, protein modification process","transferase activity, protein kinase activity","nucleus, cell cortex, cytoplasm","cell wall organization and biogenesis, nucleus, protein kinase activity, protein modification process, signal transduction",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,6,2.7,no,,,,, P131,22,B10,P131_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL101C,IZH4,,"Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism","cellular lipid metabolic process, cellular homeostasis",other,membrane,"cellular homeostasis, lipid metabolic process, membrane, other",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,19,7.7,no,,,,, P131,23,B11,P131_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL103W,ITR2,HRB612,"Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively",transport,transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,20,9.8,no,,,,, P131,24,B12,P131_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL104C,NDJ1,TAM1,"Meiosis-specific telomere protein, required for bouquet formation, effective homolog pairing, ordered cross-over distribution, sister chromatid cohesion at meiotic telomeres, chromosomal segregation and telomere-led rapid prophase movement","meiosis, chromosome organization, cell cycle, DNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, meiosis, nucleus, organelle organization and biogenesis",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,18,6.3,no,,,,, P131,25,C1,P131_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL105C,WSC3,,"Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity; involved in the response to heat shock and other stressors; regulates 1,3-beta-glucan synthesis","fungal-type cell wall organization, signaling process, cytoskeleton organization, peroxisome organization, response to stress",signal transducer activity,"membrane fraction, site of polarized growth","cell wall organization and biogenesis, cytoskeleton organization and biogenesis, membrane fraction, organelle organization and biogenesis, response to stress, signal transducer activity, signal transduction",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,22,9.9,no,,,,, P131,26,C2,P131_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL106W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,18,8.8,no,,,,, P131,27,C3,P131_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL107W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and colocalizes in a punctate pattern with the early golgi/COPI vesicles; YOL107W is not an essential protein,biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,40,15.7,no,,,,, P131,28,C4,P131_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL108C,INO4,,"Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain","cellular lipid metabolic process, transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, lipid metabolic process, nucleus, transcription, transcription regulator activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,6,1.8,no,,,,, P131,29,C5,P131_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL109W,ZEO1,,Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p; the authentic protein is detected in a phosphorylated state in highly purified mitochondria,"fungal-type cell wall organization, response to stress",molecular_function,"membrane fraction, mitochondrion, membrane, mitochondrial envelope, cytoplasm, plasma membrane","cell wall organization and biogenesis, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, plasma membrane, response to stress",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,40,17.1,no,,,,, P131,30,C6,P131_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL110W,SHR5,ERF4,"Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization","transport, protein modification process",transferase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, other, protein modification process, signal transduction, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,10,4.2,no,,,,, P131,31,C7,P131_C7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P131,32,C8,P131_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL111C,MDY2,GET5;TMA24,Protein with a role in insertion of tail-anchored proteins into the ER membrane; forms a complex with Get4p; required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes,"transport, response to chemical stimulus, conjugation, cellular component morphogenesis, cellular membrane organization",molecular_function,"nucleus, ribosome, cytoplasm","anatomical structure morphogenesis, conjugation, cytoplasm, molecular_function, nucleus, response to chemical stimulus, ribosome",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,6,2.7,no,,,,, P131,33,C9,P131_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL112W,MSB4,,"GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization",cytoskeleton organization,enzyme regulator activity,"cellular bud, cell cortex, site of polarized growth, cytoplasm","cellular bud, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, other, site of polarized growth",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,20,10.5,no,,,,, P131,34,C10,P131_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL113W,SKM1,,Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth,"transport, cytokinesis, protein modification process, cell cycle","transferase activity, protein kinase activity","nucleus, membrane, plasma membrane","cell cycle, cytokinesis, plasma membrane, protein kinase activity, protein modification process, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,4,2.2,no,,,,, P131,35,C11,P131_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL114C,,,Putative protein of unknown function with similarity to human ICT1 and prokaryotic factors that may function in translation termination; YOL114C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,16,8.7,no,,,,, P131,36,C12,P131_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL115W,PAP2,TRF4,"Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Trf5p","response to stress, DNA metabolic process, RNA metabolic process","transferase activity, nucleotidyltransferase activity, lyase activity","nucleus, nucleolus","DNA metabolic process, RNA metabolic process, cell cycle, lyase activity, nucleotidyltransferase activity, nucleus, organelle organization and biogenesis, other, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,305,64,21,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P131,37,D1,P131_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL116W,MSN1,PHD2;MSS10;HRB382;FUP1,"Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus",response to stress,transcription regulator activity,nucleus,"nucleus, other, response to stress, transcription regulator activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,6,1.8,no,,,,, P131,38,D2,P131_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL117W,RRI2,CSN10,Subunit of the COP9 signalosome (CSN) complex that cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response,"conjugation, response to chemical stimulus, protein modification process",molecular_function,nucleus,"conjugation, molecular_function, nucleus, protein modification process, response to chemical stimulus, signal transduction",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,13,6.3,no,,,,, P131,39,D3,P131_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL118C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,13,5.8,no,,,,, P131,40,D4,P131_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL119C,MCH4,,"Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport",transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,10,5.4,no,,,,, P131,41,D5,P131_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL121C,RPS19A,rp55a;YS16A;S19A;S16aA,"Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Bp","transport, translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","RNA metabolic process, cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation, transport",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,8,3.3,no,,,,, P131,42,D6,P131_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL122C,SMF1,SBS1,Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins,"transport, cellular homeostasis",transporter activity,"membrane, plasma membrane","cytoplasm, plasma membrane, transport, transporter activity, vacuole",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,3,1.3,no,,,,, P131,43,D7,P131_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL124C,TRM11,,"Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain",RNA metabolic process,"RNA binding, transferase activity",cytoplasm,"RNA binding, RNA metabolic process, cytoplasm, ribosome biogenesis, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,7,4.1,no,,,,, P131,44,D8,P131_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL126C,MDH2,,"Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1","transport, cellular carbohydrate metabolic process, peroxisome organization",oxidoreductase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, other, oxidoreductase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,16,7,no,,,,, P131,45,D9,P131_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL128C,YGK3,,"Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 family; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation","response to stress, protein modification process","transferase activity, protein kinase activity",cellular_component,"cellular_component, other, protein kinase activity, protein modification process, response to stress, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,8,2.7,no,,,,, P131,46,D10,P131_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL129W,VPS68,,Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria,"transport, vesicle-mediated transport",molecular_function,"membrane, vacuole, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrion, molecular_function, transport, vacuole, vesicle-mediated transport",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,6,3.4,no,,,,, P131,47,D11,P131_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL131W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,8,3.3,no,,,,, P131,48,D12,P131_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL132W,GAS4,,"1,3-beta-glucanosyltransferase, involved with Gas2p in spore wall assembly; has similarity to Gas1p; localizes to the cell wall","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",transferase activity,cell wall,"cell wall, cell wall organization and biogenesis, sporulation, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,7,4,no,,,,, P131,49,E1,P131_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL136C,PFK27,PFK-2,"6-phosphofructo-2-kinase, catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,10,3.6,no,,,,, P131,50,E2,P131_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL137W,BSC6,,Protein of unknown function containing 8 putative transmembrane seqments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression,biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,8,4.7,no,,,,, P131,51,E3,P131_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL138C,RTC1,,"Protein of unknown function; may interact with ribosomes, based on co-purification experiments; null mutation suppresses cdc13-1 temperature sensitivity",biological_process,molecular_function,"vacuole, ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome, vacuole",,,00_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,6,3.2,no,,,,, P131,52,E4,P131_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR232C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,333,0,0,no,,,,, P131,53,E5,P131_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR424C,DYN2,SLC1,"Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex","protein complex biogenesis, nucleus organization",molecular_function,"peroxisome, nucleus, cytoskeleton, endomembrane system, membrane, cytoplasm","cytoskeleton, cytoskeleton organization and biogenesis, endomembrane system, membrane, molecular_function, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, peroxisome",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,20,6.9,no,,,,, P131,54,E6,P131_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL011W,GLC3,GHA1,"Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,2,0.7,no,,,,, P131,55,E7,P131_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER064C,,,Non-essential nuclear protein; null mutation has global effects on transcription,transcription,molecular_function,nucleus,"molecular_function, nucleus, transcription",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,24,9.9,no,,,,, P131,56,E8,P131_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER077C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; null mutation results in a decrease in plasma membrane electron transport,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,2,1.1,no,,,,, P131,57,E9,P131_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER078C,ICP55,,"Mitochondrial aminopeptidase; cleaves the N termini of at least 38 imported proteins after cleavage by the mitochondrial processing peptidase (MPP), thereby increasing their stability; member of the aminopeptidase P family",other,"peptidase activity, hydrolase activity","nucleus, membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,20,7.2,no,,,,, P131,58,E10,P131_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER088C,DOT6,PBF2,Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; similar to Tod6p; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation,"cellular component morphogenesis, transcription, RNA metabolic process",DNA binding,"nucleus, chromosome, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, nucleus, organelle organization and biogenesis, other, transcription",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,18,6.6,no,,,,, P131,59,E11,P131_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER090W,TRP2,,"Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",lyase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, lyase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,166,2,1.2,no,,,,, P131,60,E12,P131_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER091C,MET6,,"Cobalamin-independent methionine synthase, involved in methionine biosynthesis and regeneration; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs",cellular amino acid and derivative metabolic process,transferase activity,"membrane fraction, cytoplasm","amino acid and derivative metabolic process, cytoplasm, transferase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,5,2.7,no,,,,, P131,61,F1,P131_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER092W,IES5,,Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,1,0.6,no,,,,, P131,62,F2,P131_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER093C-A,AIM11,GEP8,Protein of unknown function; null mutant is viable but shows increased loss of mitochondrial genome and synthetic interaction with prohibitin (phb1); contains an intron,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,10,3.3,no,,,,, P131,63,F3,P131_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER095W,RAD51,MUT5,"Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein","meiosis, chromosome organization, cell cycle, DNA metabolic process","hydrolase activity, DNA binding","nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, other, response to stress",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,53,21.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P131,64,F4,P131_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER096W,SHC1,,"Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH",sporulation resulting in formation of a cellular spore,enzyme regulator activity,membrane,"carbohydrate metabolic process, enzyme regulator activity, membrane, sporulation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,34,16,no,,,,, P131,65,F5,P131_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER097W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,148,2,1.4,no,,,,, P131,66,F6,P131_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER098W,UBP9,,"Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions",protein modification process,"peptidase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, peptidase activity, protein modification process",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,4,2,no,,,,, P131,67,F7,P131_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR134W,CAF130,,"Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation","transcription, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, transcription",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,10,3.2,no,,,,, P131,68,F8,P131_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR210C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,0,0,no,,,,, P131,69,F9,P131_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL024W,RIM4,,Putative RNA-binding protein required for the expression of early and middle sporulation genes,"meiosis, sporulation resulting in formation of a cellular spore, cell cycle, DNA metabolic process",RNA binding,cytoplasm,"DNA metabolic process, RNA binding, cell cycle, cytoplasm, meiosis, sporulation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,8,2.6,no,,,,, P131,70,F10,P131_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL025W,SNF6,,Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p,"response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, response to stress, transcription, transcription regulator activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,293,0,0,no,,,,, P131,71,F11,P131_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR016C,YSC84,LSB4,Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p,"transport, cytoskeleton organization, vesicle-mediated transport, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vesicle-mediated transport",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,1,0.5,no,,,,, P131,72,F12,P131_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR017W,YSC83,,"Non-essential mitochondrial protein of unknown function; mRNA induced during meiosis, peaking between mid to late prophase of meiosis I; similar to S. douglasii YSD83",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,9,3.1,no,,,,, P131,73,G1,P131_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR032W,ERC1,,Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily; overproduction confers ethionine resistance and accumulation of S-adenosylmethionine,"transport, cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",transporter activity,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,5,2.9,no,,,,, P131,74,G2,P131_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR045W,,,Putative protein of unknown function; possible role in iron metabolism and/or amino acid and carbohydrate metabolism; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,6,2.5,no,,,,, P131,75,G3,P131_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR064C,SSZ1,PDR13,Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP,"translation, ribosome biogenesis, RNA metabolic process",protein binding,cytoplasm,"cytoplasm, protein binding, translation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,6,3.1,no,,,,, P131,76,G4,P131_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR140W,,,Putative integral membrane protein of unknown function,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,4,1.6,no,,,,, P131,77,G5,P131_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR162W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,6,3.1,no,,,,, P131,78,G6,P131_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR168W,MTG2,,"Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly",translation,hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, other, translation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,2,0.7,no,,,,, P131,79,G7,P131_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR181W,SVP26,ERV26,"Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment","transport, fungal-type cell wall organization, protein modification process, cellular carbohydrate metabolic process, vesicle-mediated transport",protein binding,"endomembrane system, cytoplasmic membrane-bounded vesicle, membrane, endoplasmic reticulum, Golgi apparatus, cytoplasm","Golgi apparatus, cell wall organization and biogenesis, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, endoplasmic reticulum, membrane, other, protein binding, protein modification process, transport, vesicle-mediated transport",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,4,1.3,no,,,,, P131,80,G8,P131_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR191C,CTF8,,Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion,"response to stress, chromosome organization, cell cycle, chromosome segregation",molecular_function,chromosome,"cell cycle, chromosome, molecular_function, organelle organization and biogenesis, response to stress",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,463,26,5.6,no,,,,, P131,81,G9,P131_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR193C,EGD2,,"Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes",protein folding,"protein binding, lipid binding",cytoplasm,"cytoplasm, protein binding, protein folding",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,11,4.7,no,,,,, P131,82,G10,P131_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL030C,RRT7,,"Identified in a screen for mutants with increased levels of rDNA transcription; dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,0,0,no,,,,, P131,83,G11,P131_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL044W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLL044W and the overlapping gene RPL8B is reduced in the gcr1 null mutant",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,4,1.7,no,,,,, P131,84,G12,P131_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL048C,YBT1,BAT1,Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mammalian bile transporters,transport,"transporter activity, hydrolase activity","vacuole, cytoplasm","cytoplasm, hydrolase activity, transport, transporter activity, vacuole",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,231,1,0.4,no,,,,, P131,85,H1,P131_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL049W,LDB18,,"Component of the dynactin complex, which is required for dynein activity; null mutant exhibits defects in nuclear migration and spindle orientation and has reduced affinity for alcian blue dye; has homology to mammalian dynactin subunit p24","cytoskeleton organization, cell cycle",molecular_function,"cell cortex, cytoskeleton, microtubule organizing center, cytoplasm","biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,10,5.6,no,,,,, P131,86,H2,P131_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL059C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,1,0.5,no,,,,, P131,87,H3,P131_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P131,88,H4,P131_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR030W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,1,0.5,no,,,,, P131,89,H5,P131_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR031W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,1,0.5,no,,,,, P131,90,H6,P131_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR032W,RAD5,SNM2;REV2,DNA helicase proposed to promote replication fork regression during postreplication repair by template switching; RING finger containing ubiquitin ligase; stimulates the synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p,"protein modification process, protein complex biogenesis, response to stress, DNA metabolic process, cellular homeostasis","hydrolase activity, DNA binding, helicase activity","nucleus, chromosome","DNA binding, DNA metabolic process, chromosome, helicase activity, hydrolase activity, nucleus, response to stress",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,9,4.9,no,,,,, P131,91,H7,P131_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR034C,SMF3,,Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins,"transport, cellular homeostasis",transporter activity,"membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, membrane, transporter activity, vacuole",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,0,0,no,,,,, P131,92,H8,P131_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR035C,MLH2,,Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination; forms a complex with Mlh1p,"response to stress, meiosis, cell cycle, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, cell cycle, meiosis, molecular_function, nucleus, response to stress",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,289,0,0,no,,,,, P131,93,H9,P131_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR036C,,,Putative protein of unknown function predicted to have transmembrane domains; interacts with HSP90 by yeast two-hybrid analysis; YLR036C is not an essential protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,1,0.4,no,,,,, P131,94,H10,P131_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR037C,PAU23,DAN2,"Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; member of the seripauperin multigene family encoded mainly in subtelomeric regions; expressed under anaerobic conditions, completely repressed during aerobic growth",biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,8,3.6,no,,,,, P131,95,H11,P131_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR038C,COX12,,"Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated","mitochondrion organization, protein complex biogenesis","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, oxidoreductase activity, transporter activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,331,0,0,no,,,,, P131,96,H12,P131_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR039C,RIC1,,Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes,"transport, vesicle-mediated transport",enzyme regulator activity,"nucleus, membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, enzyme regulator activity, membrane, nucleus, other, transport, vesicle-mediated transport",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,1,0.5,no,,,,, P132,1,A1,P132_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR040C,,,Putative protein of unknown function; localizes to the cell wall; predicted to be a GPI-attached protein; upregulated by Mcm1p-Alpha1p transcription factor; partially overlaps the dubious ORF YLR041W; YLR040C is not essential,biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,20,7.1,no,,,,, P132,2,A2,P132_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR041W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YLR040C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,28,10.2,no,,,,, P132,3,A3,P132_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR050C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,44,14.6,no,,,,, P132,4,A4,P132_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR052W,IES3,,Subunit of the INO80 chromatin remodeling complex,"chromosome organization, transcription, DNA metabolic process, RNA metabolic process",molecular_function,"nucleus, chromosome","RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, transcription",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,58,20.6,no,,,,, P132,5,A5,P132_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR142C,RPL13B,L13B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Ap; not essential for viability; has similarity to rat L13 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,7,3.6,no,,,,, P132,6,A6,P132_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR158W,MRPS8,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,18,9.4,no,,,,, P132,7,A7,P132_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR171C,EAR1,,Specificity factor required for Rsp5p-dependent ubiquitination and sorting of specific cargo proteins at the multivesicular body; mRNA is targeted to the bud via the mRNA transport system involving She2p,"transport, vesicle-mediated transport, cellular protein catabolic process",molecular_function,cytoplasm,"cytoplasm, molecular_function, protein catabolic process, transport, vesicle-mediated transport",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,4,1.9,no,,,,, P132,8,A8,P132_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR181C,,,Protein of unknown function; mRNA transcribed as part of a bicistronic transcript with a predicted transcriptional repressor RGM1/YMR182C; mRNA is destroyed by nonsense-mediated decay (NMD); YMR181C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,1,0.5,no,,,,, P132,9,A9,P132_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR209C,,,Putative S-adenosylmethionine-dependent methyltransferase; YMR209C is not an essential gene,biological_process,transferase activity,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,7,3.6,no,,,,, P132,10,A10,P132_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR271C,URA10,,"Minor orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; major OPRTase encoded by URA5","heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, other, transferase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,4,2.1,no,,,,, P132,11,A11,P132_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR279C,,,"Putative paralog of ATR1, but not required for boron tolerance; identified as a heat-induced gene in a high-throughout screen; YMR279C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,9,3.5,no,,,,, P132,12,A12,P132_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR306W,FKS3,,"Protein involved in spore wall assembly, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",transferase activity,"mitochondrion, cytoplasm","cell wall organization and biogenesis, mitochondrion, sporulation, transferase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,6,2.6,no,,,,, P132,13,B1,P132_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR311C,GLC8,,"Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2","cellular carbohydrate metabolic process, generation of precursor metabolites and energy, chromosome segregation",enzyme regulator activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, enzyme regulator activity, generation of precursor metabolites and energy, nucleus, other",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,42,13,no,,,,, P132,14,B2,P132_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR312W,ELP6,KTI4;TOT6;HAP3,"Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity","transcription, protein modification process, RNA metabolic process",molecular_function,other,"RNA metabolic process, molecular_function, other, protein modification process, transcription",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,31,16.1,no,,,,, P132,15,B3,P132_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR313C,TGL3,,Bifunctional enzyme with triacylglycerol lipase and lysophosphatidylethanolamine acyltransferase activity; responsible for all the triacylglycerol lipase activity of the lipid particle; required with Tgl4p for timely bud formation,"cell budding, cellular lipid metabolic process","transferase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, lipid metabolic process",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,21,11.1,no,,,,, P132,16,B4,P132_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR315W,,,Protein with NADP(H) oxidoreductase activity; transcription is regulated by Stb5p in response to NADPH depletion induced by diamide; promoter contains a putative Stb5p binding site,cofactor metabolic process,oxidoreductase activity,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,5,2.8,no,,,,, P132,17,B5,P132_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR316C-A,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene DIA1/YMR316W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,40,11.9,no,,,,, P132,18,B6,P132_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR316C-B,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,8,4.1,no,,,,, P132,19,B7,P132_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR316W,DIA1,,"Protein of unknown function, involved in invasive and pseudohyphal growth; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern",pseudohyphal growth,molecular_function,cytoplasm,"cytoplasm, molecular_function, other, pseudohyphal growth",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,5,2.6,no,,,,, P132,20,B8,P132_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR317W,,,Putative protein of unknown function with some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,16,8.9,no,,,,, P132,21,B9,P132_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR318C,ADH6,ADHVI,NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance,heterocycle metabolic process,oxidoreductase activity,other,"heterocycle metabolic process, other, oxidoreductase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,9,4.1,no,,,,, P132,22,B10,P132_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR319C,FET4,,Low-affinity Fe(II) transporter of the plasma membrane,transport,transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,11,5.4,no,,,,, P132,23,B11,P132_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR320W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,44,13.8,no,,,,, P132,24,B12,P132_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL250W,RAD50,,"Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining","response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process","transferase activity, hydrolase activity, DNA binding, protein binding","nucleus, mitochondrion, cytoplasm","DNA binding, DNA metabolic process, cell cycle, hydrolase activity, meiosis, mitochondrion, nucleus, organelle organization and biogenesis, other, protein binding, response to stress, transferase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,303,40,13.2,no,,,,, P132,25,C1,P132_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL252C,MRPL17,YmL17;YmL30;MRPL30,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,4,2,no,,,,, P132,26,C2,P132_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL279W,PRM1,,Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p,"conjugation, response to chemical stimulus, cellular membrane organization",molecular_function,"membrane, site of polarized growth","conjugation, membrane, membrane organization and biogenesis, molecular_function, response to chemical stimulus, site of polarized growth",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,6,2.2,no,,,,, P132,27,C3,P132_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL300W,TOS6,,"Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid",biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,0,0,no,,,,, P132,28,C4,P132_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL316C,PHA2,,"Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",lyase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, lyase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,185,3,1.6,no,,,,, P132,29,C5,P132_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL016C,CMK2,,"Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk1p and mammalian Cam Kinase II","signaling process, protein modification process","transferase activity, protein kinase activity",cytoplasm,"cytoplasm, protein kinase activity, protein modification process, signal transduction, transferase activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,8,3.7,no,,,,, P132,30,C6,P132_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR096W,RPS7A,rp30;S7A;RPS30,"Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins","translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,15,8.8,no,,,,, P132,31,C7,P132_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR306C,MCH5,,"Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,18,7,no,,,,, P132,32,C8,P132_C8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P132,33,C9,P132_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR317W,FAA1,,"Long chain fatty acyl-CoA synthetase, activates imported fatty acids with a preference for C12:0-C16:0 chain lengths; functions in long chain fatty acid import; accounts for most acyl-CoA synthetase activity; localized to lipid particles","transport, cofactor metabolic process",ligase activity,"membrane, membrane fraction, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, ligase activity, lipid metabolic process, membrane, mitochondrial envelope, mitochondrion, protein modification process, transport",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,8,2.4,no,,,,, P132,34,C10,P132_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL132W,COX11,PSO7;LPI13,Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p,"generation of precursor metabolites and energy, protein complex biogenesis, cellular respiration",other,"ribosome, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, other, ribosome",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,218,4,1.8,no,,,,, P132,35,C11,P132_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL134C,ODC1,2-oxodicarboxylate transporter,"Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for lysine and glutamate biosynthesis and lysine catabolism; suppresses, in multicopy, an fmc1 null mutation",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,00_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,14,6.7,no,,,,, P132,36,C12,P132_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML124C,TUB3,,"Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p","transport, chromosome segregation, meiosis, conjugation, chromosome organization, cell cycle",structural molecule activity,"nucleus, cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, conjugation, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, meiosis, microtubule organizing center, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, structural molecule activity, transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,16,7.7,no,,,,, P132,37,D1,P132_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML070W,DAK1,,"Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation","response to stress, cellular carbohydrate metabolic process",transferase activity,cytoplasm,"cytoplasm, other, response to stress, transferase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,20,7.8,no,,,,, P132,38,D2,P132_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML071C,COG8,DOR1,"Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","transport, vesicle-mediated transport",molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, molecular_function, transport, vesicle-mediated transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,30,15.5,no,,,,, P132,39,D3,P132_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML074C,FPR3,NPI46,Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p,"meiosis, signaling process, cell cycle",isomerase activity,"nucleus, nucleolus","cell cycle, isomerase activity, meiosis, nucleolus",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,7,3,no,,,,, P132,40,D4,P132_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML090W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,10,3.8,no,,,,, P132,41,D5,P132_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML094W,GIM5,PFD5,Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it,protein complex biogenesis,protein binding,cytoplasm,"cytoplasm, other, protein binding",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,4,2.3,no,,,,, P132,42,D6,P132_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML095C,RAD10,,"Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein","response to stress, meiosis, cell cycle, DNA metabolic process","DNA binding, hydrolase activity",nucleus,"DNA binding, DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, response to stress",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,16,8.2,no,,,,, P132,43,D7,P132_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML096W,,,Putative protein of unknown function with similarity to asparagine synthetases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YML096W is not an essential gene and partially overlaps the verified gene RAD10,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,24,8.1,no,,,,, P132,44,D8,P132_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML097C,VPS9,VPT9;VPL31,A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin,"vacuole organization, transport","protein binding, enzyme regulator activity",cytoplasm,"cytoplasm, enzyme regulator activity, transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,14,4.6,no,,,,, P132,45,D9,P132_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML099C,ARG81,ARGRII;ARGR2,"Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p","transport, vesicle-mediated transport, cellular amino acid and derivative metabolic process","transcription regulator activity, protein binding",nucleus,"amino acid and derivative metabolic process, nucleus, protein binding, transcription regulator activity, transport, vesicle-mediated transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,0,0,no,,,,, P132,46,D10,P132_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML100W,TSL1,,"Large subunit of trehalose 6-phosphate synthase (Tps1p)/phosphatase (Tps2p) complex, which converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose, homologous to Tps3p and may share function","response to stress, cellular carbohydrate metabolic process","transferase activity, hydrolase activity, enzyme regulator activity",cytoplasm,"carbohydrate metabolic process, cytoplasm, enzyme regulator activity, hydrolase activity, response to stress, transferase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,14,5.2,no,,,,, P132,47,D11,P132_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML099W-A,,YML100W-A,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF ARG81/YML099C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,26,8.4,no,,,,, P132,48,D12,P132_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML101C,CUE4,,"Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination",biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endoplasmic reticulum, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,18,7.6,no,,,,, P132,49,E1,P132_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML101C-A,,YML102C-A,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,2,0.9,no,,,,, P132,50,E2,P132_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML102W,CAC2,,"Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans","response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",transcription regulator activity,"nucleus, chromosome","DNA metabolic process, RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, response to stress, transcription, transcription regulator activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,16,6.4,no,,,,, P132,51,E3,P132_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML103C,NUP188,,"Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p","transport, ribosome biogenesis, nucleus organization",structural molecule activity,"nucleus, membrane, endomembrane system","endomembrane system, membrane, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, structural molecule activity, transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,4,2.2,no,,,,, P132,52,E4,P132_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML104C,MDM1,,"Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)",mitochondrion organization,"structural molecule activity, lipid binding","cytoskeleton, cytoplasm","cytoplasm, cytoskeleton, lipid binding, organelle organization and biogenesis, other, structural molecule activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,16,5.3,no,,,,, P132,53,E5,P132_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML106W,URA5,PYR5,"Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10","heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, nucleus, other, transferase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,18,9.9,no,,,,, P132,54,E6,P132_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML107C,PML39,,Protein required for nuclear retention of unspliced pre-mRNAs along with Mlp1p and Pml1p; anchored to nuclear pore complex via Mlp1p and Mlp2p; found with the subset of nuclear pores farthest from the nucleolus; may interact with ribosomes,other,molecular_function,"nucleus, membrane, endomembrane system, ribosome, cytoplasm","endomembrane system, membrane, molecular_function, nucleus, ribosome, transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,10,5.5,no,,,,, P132,55,E7,P132_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML108W,,,Putative protein of unknown function whose structure defines a new subfamily of the split beta-alpha-beta sandwiches; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YML108W is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,38,12.2,no,,,,, P132,56,E8,P132_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML109W,ZDS2,CES4,"Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; implicated in the mitotic exit network through regulation of Cdc14p localization; paralog of Zds1p","transcription, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, anatomical structure morphogenesis, molecular_function, nucleus, organelle organization and biogenesis, other, transcription",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,0,0,no,,,,, P132,57,E9,P132_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML110C,COQ5,"2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase;DBI56","2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",transferase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, transferase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,182,11,6,no,,,,, P132,58,E10,P132_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML111W,BUL2,,"Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1",protein modification process,protein binding,cytoplasm,"cytoplasm, other, protein binding, protein modification process",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,11,5.5,no,,,,, P132,59,E11,P132_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML112W,CTK3,,"Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity","translation, transcription, protein modification process, RNA metabolic process","transferase activity, protein kinase activity","nucleus, nucleolus","RNA metabolic process, nucleus, protein kinase activity, protein modification process, transcription, transferase activity, translation",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,0,0,no,,,,, P132,60,E12,P132_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML113W,DAT1,,DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability,"transcription, RNA metabolic process",DNA binding,nucleus,"DNA binding, RNA metabolic process, nucleus, transcription",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,12,3.6,no,,,,, P132,61,F1,P132_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML116W,ATR1,SNQ1,"Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide","transport, response to chemical stimulus",transporter activity,"membrane, vacuole, plasma membrane, cytoplasm","plasma membrane, response to chemical stimulus, transport, transporter activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,39,19.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P132,62,F2,P132_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML117W,NAB6,,Putative RNA-binding protein that associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP,biological_process,molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,13,5.2,no,,,,, P132,63,F3,P132_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML116W-A,,YML117W-A,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,19,9,no,,,,, P132,64,F4,P132_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML118W,NGL3,,"Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p",biological_process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,22,10.7,no,,,,, P132,65,F5,P132_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML119W,,,Putative protein of unknown function; YML119W is not an essential gene; potential Cdc28p substrate,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,13,7.5,no,,,,, P132,66,F6,P132_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML120C,NDI1,,"NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; homolog of human AMID","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, other, oxidoreductase activity, vitamin metabolic process",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,27,14.8,no,,,,, P132,67,F7,P132_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML121W,GTR1,,"Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB","transport, transcription, RNA metabolic process",other,"nucleus, membrane, vacuole, cytoplasm","RNA metabolic process, cytoplasm, membrane, nucleus, organelle organization and biogenesis, other, transcription, transport, vacuole",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,2,0.8,no,,,,, P132,68,F8,P132_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML122C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,36,16.5,no,,,,, P132,69,F9,P132_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML123C,PHO84,phoT,High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p,transport,transporter activity,"membrane, plasma membrane","membrane, other, plasma membrane, transport, transporter activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,6,2.7,no,,,,, P132,70,F10,P132_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML128C,MSC1,,"Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated","meiosis, cell cycle, DNA metabolic process",molecular_function,"membrane fraction, mitochondrion, endoplasmic reticulum, cytoplasm","DNA metabolic process, cell cycle, endoplasmic reticulum, meiosis, mitochondrion, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,195,18,9.2,no,,,,, P132,71,F11,P132_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML129C,COX14,,"Mitochondrial membrane protein, involved in translational regulation of Cox1p and assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes","mitochondrion organization, translation",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, molecular_function, translation",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,7,3.6,no,,,,, P132,72,F12,P132_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML131W,,,"Putative protein of unknown function with similarity to medium chain dehydrogenase/reductases; expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals; GFP-fusion protein localizes to the cytoplasm",biological_process,molecular_function,cytoplasm,"cytoplasm, molecular_function, response to chemical stimulus, response to stress",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,14,5,no,,,,, P132,73,G1,P132_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR004W,MVP1,,Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole,transport,lipid binding,cytoplasm,"cytoplasm, lipid binding, transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,24,10.1,no,,,,, P132,74,G2,P132_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR095C,SNO1,,"Protein of unconfirmed function, involved in pyridoxine metabolism; expression is induced during stationary phase; forms a putative glutamine amidotransferase complex with Snz1p, with Sno1p serving as the glutaminase","vitamin metabolic process, heterocycle metabolic process",molecular_function,cytoplasm,"cytoplasm, molecular_function, other, vitamin metabolic process",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,18,6.3,no,,,,, P132,75,G3,P132_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR096W,SNZ1,,"Protein involved in vitamin B6 biosynthesis; member of a stationary phase-induced gene family; coregulated with SNO1; interacts with Sno1p and with Yhr198p, perhaps as a multiprotein complex containing other Snz and Sno proteins","vitamin metabolic process, heterocycle metabolic process",protein binding,cellular_component,"cellular_component, protein binding, vitamin metabolic process",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,32,10.4,no,,,,, P132,76,G4,P132_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR097C,MTG1,,"Putative GTPase peripheral to the mitochondrial inner membrane, essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals","mitochondrion organization, translation",hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, ribosome biogenesis, translation",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,42,13,no,,,,, P132,77,G5,P132_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR098C,ATP25,LRC4,Mitochondrial protein required for the stability of Oli1p (Atp9p) mRNA and for the Oli1p ring formation; YMR098C is not an essential gene,"mitochondrion organization, protein complex biogenesis, RNA metabolic process",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","RNA metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P132,78,G6,P132_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR099C,,hexose-6-phosphate mutarotase;glucose-6-phosphate 1-epimerase,"Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase), likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS",cellular carbohydrate metabolic process,isomerase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, isomerase activity, nucleus",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,18,6,no,,,,, P132,79,G7,P132_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR100W,MUB1,,MYND domain-containing protein required for ubiquitination and turnover of Rpn4p; interacts with Ubr2p (E3) and indirectly with Rad6p (E2); short-lived protein degraded in a Ubr2p/Rad6p dependent manner; similar to the A. nidulans samB gene,"cell budding, protein modification process",molecular_function,cellular_component,"cell budding, cellular_component, molecular_function, protein modification process",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,27,11.6,no,,,,, P132,80,G8,P132_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR101C,SRT1,,Cis-prenyltransferase involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase,"cellular carbohydrate metabolic process, protein modification process",transferase activity,cytoplasm,"cytoplasm, protein modification process, transferase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,4,1.7,no,,,,, P132,81,G9,P132_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR102C,,,Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,10,5.1,no,,,,, P132,82,G10,P132_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR103C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,10,4.5,no,,,,, P132,83,G11,P132_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR105C,PGM2,GAL5,"Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase","cellular carbohydrate metabolic process, generation of precursor metabolites and energy, cellular homeostasis",isomerase activity,cytoplasm,"carbohydrate metabolic process, cellular homeostasis, cytoplasm, generation of precursor metabolites and energy, isomerase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,2,0.9,no,,,,, P132,84,G12,P132_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR106C,YKU80,HDF2,"Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair","response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process","RNA binding, DNA binding","nucleus, chromosome","DNA binding, DNA metabolic process, RNA binding, RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, response to stress, transcription",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,10,3.4,no,,,,, P132,85,H1,P132_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR107W,SPG4,,Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,24,13.8,no,,,,, P132,86,H2,P132_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR109W,MYO5,,"One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization","transport, fungal-type cell wall organization, cell budding, cytokinesis, response to stress, vesicle-mediated transport, cell cycle, cellular membrane organization","motor activity, hydrolase activity","cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cell wall organization and biogenesis, cytokinesis, cytoplasm, cytoskeleton, membrane organization and biogenesis, motor activity, other, response to stress, transport, vesicle-mediated transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,8,2.5,no,,,,, P132,87,H3,P132_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P132,88,H4,P132_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR110C,HFD1,,"Putative fatty aldehyde dehydrogenase, located in the mitochondrial outer membrane and also in lipid particles; has similarity to human fatty aldehyde dehydrogenase (FALDH) which is implicated in Sjogren-Larsson syndrome",other,oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, other, oxidoreductase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,28,8.7,no,,,,, P132,89,H5,P132_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR111C,,,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR111C is not an essential gene,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,14,8,no,,,,, P132,90,H6,P132_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR114C,,,"Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR114C is not an essential gene",biological_process,molecular_function,"nucleus, ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus, ribosome",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,16,4.8,no,,,,, P132,91,H7,P132_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR115W,MGR3,FMP24,"Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr1p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA",cellular protein catabolic process,protein binding,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,8,2.7,no,,,,, P132,92,H8,P132_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR116C,ASC1,CPC2,G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation,"translation, response to chemical stimulus","signal transducer activity, protein binding, enzyme regulator activity","ribosome, cytoplasm","DNA metabolic process, cytoplasm, enzyme regulator activity, other, protein binding, response to chemical stimulus, ribosome, signal transducer activity, signal transduction, translation, transposition",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,2,0.6,no,,,,, P132,93,H9,P132_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR119W-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,11,5.3,no,,,,, P132,94,H10,P132_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR120C,ADE17,,"Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine",heterocycle metabolic process,"transferase activity, hydrolase activity","membrane fraction, cytoplasm","cytoplasm, hydrolase activity, other, transferase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,8,4.3,no,,,,, P132,95,H11,P132_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR121C,RPL15B,rp15R;YL10;L15B;L13B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA",translation,"RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, ribosome, structural molecule activity, translation",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,20,10.5,no,,,,, P132,96,H12,P132_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR122C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,6,3.4,no,,,,, P133,1,A1,P133_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR123W,PKR1,,"V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0)",protein complex biogenesis,molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, other",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,8,3.1,no,,,,, P133,2,A2,P133_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR124W,,,"Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene; predicted to have a role in organelle organization",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,20,11,no,,,,, P133,3,A3,P133_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR125W,STO1,SUT1;CBP80;GCR3;CBC1,"Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80",RNA metabolic process,RNA binding,nucleus,"RNA binding, RNA metabolic process, nucleus, other",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,32,12.9,no,,,,, P133,4,A4,P133_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR126C,DLT1,,"Protein of unknown function, mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA)",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,3,1.7,no,,,,, P133,5,A5,P133_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR127C,SAS2,KAT8,"Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family","chromosome organization, transcription, protein modification process, RNA metabolic process",transferase activity,"nucleus, chromosome","RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, protein modification process, transcription, transferase activity",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,24,7.6,no,,,,, P133,6,A6,P133_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR129W,POM152,,Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase;,"transport, ribosome biogenesis, nucleus organization",structural molecule activity,"nucleus, endomembrane system, mitochondrion, membrane, cytoplasm","endomembrane system, membrane, mitochondrion, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, structural molecule activity, transport",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,42,19.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P133,7,A7,P133_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR130W,,,Putative protein of unknown function; YMR130W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,4,1.8,no,,,,, P133,8,A8,P133_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR132C,JLP2,,"Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,38,13.3,no,,,,, P133,9,A9,P133_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR133W,REC114,,Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division,"meiosis, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleus",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,30,9.8,no,,,,, P133,10,A10,P133_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR135C,GID8,DCR1,"Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p; dosage-dependent regulator of START","cellular carbohydrate metabolic process, cell cycle, cellular protein catabolic process",molecular_function,"nucleus, cytoplasm","carbohydrate metabolic process, cell cycle, cytoplasm, molecular_function, nucleus, other, protein catabolic process",,,00_9,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,32,13.9,no,,,,, P133,11,A11,P133_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR006C,ICL2,,"2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol",cellular amino acid and derivative metabolic process,lyase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, lyase activity, mitochondrion, other",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,32,9.9,no,,,,, P133,12,A12,P133_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR009W,SUT2,,Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p,"transport, transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity, transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,20,8.2,no,,,,, P133,13,B1,P133_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR012W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR012W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,14,6,no,,,,, P133,14,B2,P133_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR014C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR014C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,36,14.2,no,,,,, P133,15,B3,P133_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR015C,,,Putative protein of unknown function; overexpression causes a cell cycle delay or arrest,biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,20,9.2,no,,,,, P133,16,B4,P133_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR017C,DSS4,,"Guanine nucleotide dissociation stimulator for Sec4p, functions in the post-Golgi secretory pathway; binds zinc, found both on membranes and in the cytosol","transport, vesicle-mediated transport",enzyme regulator activity,membrane fraction,"enzyme regulator activity, membrane fraction, other, transport, vesicle-mediated transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,4,2.3,no,,,,, P133,17,B5,P133_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR018W,RLF2,CAC1,Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin,"chromosome organization, transcription, RNA metabolic process",transcription regulator activity,"nucleus, chromosome","RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,20,9.1,no,,,,, P133,18,B6,P133_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR020W,ATP20,,Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex,"transport, mitochondrion organization, heterocycle metabolic process, protein complex biogenesis, cellular membrane organization",structural molecule activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, other, structural molecule activity, transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,20,8.7,no,,,,, P133,19,B7,P133_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR027C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,30,9.1,no,,,,, P133,20,B8,P133_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR028W,YOP1,YIP2,Membrane protein that interacts with Yip1p to mediate membrane traffic; interacts with Sey1p to maintain ER morphology; overexpression leads to cell death and accumulation of internal cell membranes,"transport, vesicle-mediated transport, protein complex biogenesis, nucleus organization",protein binding,membrane,"membrane, protein binding, vesicle-mediated transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,16,5.2,no,,,,, P133,21,B9,P133_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR029C,APL4,,"Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport","transport, vesicle-mediated transport",protein binding,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, protein binding, transport, vesicle-mediated transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,16,5.8,no,,,,, P133,22,B10,P133_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR030W,CSR2,ART8;MRG19,"Nuclear protein proposed to regulate utilization of nonfermentable carbon sources and endocytosis of plasma membrane proteins; overproduction suppresses chs5 spa2 lethality at high temp; ubiquitinated by Rsp5p, deubiquitinated by Ubp2p","transport, fungal-type cell wall organization, vesicle-mediated transport, transcription, cellular membrane organization, RNA metabolic process",protein binding,nucleus,"RNA metabolic process, cell wall organization and biogenesis, molecular_function, nucleus, transcription",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,32,15.2,no,,,,, P133,23,B11,P133_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR032W,SRO7,SOP1;SNI1,"Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro77p and Drosophila lgl tumor suppressor","transport, vesicle-mediated transport, signaling process","protein binding, enzyme regulator activity","membrane, plasma membrane, cytoplasm","anatomical structure morphogenesis, cytoplasm, enzyme regulator activity, plasma membrane, protein binding, signal transduction, transport, vesicle-mediated transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,20,11.4,no,,,,, P133,24,B12,P133_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR036W,VMA13,CLS11,"Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,2,0.9,no,,,,, P133,25,C1,P133_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR038W,IRC16,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene YPR037C; null mutant displays increased levels of spontaneous Rad52p foci",DNA metabolic process,molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,48,19.8,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P133,26,C2,P133_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR039W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified non essential genes ERV2/YPR037C and TIP41/YPR040W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,20,6.8,no,,,,, P133,27,C3,P133_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR040W,TIP41,,"Protein that interacts physically and genetically with Tap42p, which regulates protein phosphatase 2A; component of the TOR (target of rapamycin) signaling pathway",signaling process,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, signal transduction",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,21,11.9,no,,,,, P133,28,C4,P133_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR042C,PUF2,,"Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins",RNA metabolic process,RNA binding,cytoplasm,"RNA binding, RNA metabolic process, cytoplasm",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,16,6.1,no,,,,, P133,29,C5,P133_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR044C,OPI11,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene RPL43A/YPR043W; deletion confers sensitivity to GSAO",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,23,12.6,no,,,,, P133,30,C6,P133_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR045C,,MNI2,Protein of unknown function; involvement in splicing based on pre-mRNA accumulation defect for many intron-containing genes; contains a SAC3 domain; physically interacts with Csn12p; YRP045C is not an essential gene,RNA metabolic process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,10,3.3,no,,,,, P133,31,C7,P133_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR046W,MCM16,,Protein involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA,"chromosome organization, cell cycle, chromosome segregation",protein binding,"nucleus, chromosome","chromosome, nucleus, other, protein binding",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,14,6.4,no,,,,, P133,32,C8,P133_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR047W,MSF1,mitochondrial phenylalanyl-tRNA synthetase,"Mitochondrial phenylalanyl-tRNA synthetase, active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase","mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,28,8.7,no,,,,, P133,33,C9,P133_C9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P133,34,C10,P133_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR049C,ATG11,CVT9,Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; directs receptor-bound cargo to the phagophore assembly site (PAS) for packaging into vesicles; required for recruiting other proteins to the (PAS),"transport, peroxisome organization, cellular membrane organization","structural molecule activity, protein binding","membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, other, protein binding, transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,4,1.3,no,,,,, P133,35,C11,P133_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR051W,MAK3,NAA30,Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus,protein modification process,transferase activity,cytoplasm,"cytoplasm, protein modification process, transferase activity",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,0,0,no,,,,, P133,36,C12,P133_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR052C,NHP6A,,High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Bp; homologous to mammalian HMGB1 and HMGB2,"response to stress, chromosome organization, transcription, DNA metabolic process, protein complex biogenesis, RNA metabolic process",DNA binding,nucleus,"RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, other, transcription",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,14,4.5,no,,,,, P133,37,D1,P133_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR053C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene NHP6A/YPR052C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,4,1.7,no,,,,, P133,38,D2,P133_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR054W,SMK1,,Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis, protein modification process","transferase activity, signal transducer activity, protein kinase activity","mitochondrion, cytoplasm","cell wall organization and biogenesis, mitochondrion, protein kinase activity, protein modification process, signal transducer activity, sporulation, transferase activity",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,0,0,no,,,,, P133,39,D3,P133_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR057W,BRR1,,"snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed",RNA metabolic process,RNA binding,nucleus,"RNA binding, RNA metabolic process, nucleus",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,44,17.3,no,,,,, P133,40,D4,P133_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR058W,YMC1,,"Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc2p",transport,transporter activity,"mitochondrion, cytoplasm","mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P133,41,D5,P133_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR059C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YMC1/YPR058W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,28,11.1,no,,,,, P133,42,D6,P133_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR060C,ARO7,TYR7;OSM2;HGS1,"Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",isomerase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, isomerase activity, nucleus",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,8,2.6,no,,,,, P133,43,D7,P133_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR061C,JID1,,"Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,2,0.9,no,,,,, P133,44,D8,P133_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR062W,FCY1,yCD,"Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU)","heterocycle metabolic process, cellular aromatic compound metabolic process",hydrolase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, hydrolase activity, nucleus, other",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,22,9.4,no,,,,, P133,45,D9,P133_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR063C,,,ER-localized protein of unknown function,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,166,12,7.2,no,,,,, P133,46,D10,P133_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR065W,ROX1,REO1,Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity,"transcription, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, chromosome","DNA binding, RNA metabolic process, chromosome, nucleus, transcription, transcription regulator activity",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,12,3.7,no,,,,, P133,47,D11,P133_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR066W,UBA3,,"Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern",protein modification process,other,cytoplasm,"cytoplasm, other, protein modification process",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,14,5.2,no,,,,, P133,48,D12,P133_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR068C,HOS1,,"Class I histone deacetylase (HDAC) family member that also deacetylates Smc3p at anaphase onset; has sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; interacts with the Tup1p-Ssn6p corepressor complex","chromosome organization, transcription, protein modification process, RNA metabolic process",hydrolase activity,nucleus,"RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, protein modification process, transcription",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,11,5.9,no,,,,, P133,49,E1,P133_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR069C,SPE3,,"Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells","cofactor metabolic process, cellular amino acid and derivative metabolic process",transferase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, nucleus, transferase activity",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,54,20.9,no,,,,, P133,50,E2,P133_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR070W,MED1,,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,181,44,24.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P133,51,E3,P133_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR071W,,,Putative membrane protein; YPR071W is not an essential gene,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,0,0,no,,,,, P133,52,E4,P133_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR073C,LTP1,,Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine,protein modification process,"phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,8,4.6,no,,,,, P133,53,E5,P133_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR074C,TKL1,,"Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids","cofactor metabolic process, cellular carbohydrate metabolic process",transferase activity,cytoplasm,"carbohydrate metabolic process, cofactor metabolic process, cytoplasm, transferase activity, vitamin metabolic process",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,10,4.3,no,,,,, P133,54,E6,P133_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR075C,OPY2,,Integral membrane protein that functions in the signaling branch of the high-osmolarity glycerol (HOG) pathway; interacts with Ste50p; overproduction blocks cell cycle arrest in the presence of mating pheromone,"response to chemical stimulus, response to stress, conjugation, cell cycle",molecular_function,"vacuole, membrane, cytoplasm, plasma membrane","cell cycle, conjugation, cytoplasm, membrane, molecular_function, plasma membrane, response to chemical stimulus, response to stress, signal transduction, vacuole",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,2,0.7,no,,,,, P133,55,E7,P133_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR076W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,36,13.5,no,,,,, P133,56,E8,P133_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR077C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression increased by deletion of NAP1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,13,6.6,no,,,,, P133,57,E9,P133_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR079W,MRL1,,"Membrane protein with similarity to mammalian mannose-6-phosphate receptors, possibly functions as a sorting receptor in the delivery of vacuolar hydrolases",transport,other,cytoplasm,"cytoplasm, other, transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,4,1.3,no,,,,, P133,58,E10,P133_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR084W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,12,5.8,no,,,,, P133,59,E11,P133_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR087W,VPS69,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene SRP54; deletion causes a vacuolar protein sorting defect",transport,molecular_function,cellular_component,"cellular_component, molecular_function, transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,52,15.5,no,,,,, P133,60,E12,P133_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR089W,,YPR090W,Protein of unknown function; exhibits genetic interaction with ERG11 and protein-protein interaction with Hsp82p,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,56,17.9,no,,,,, P133,61,F1,P133_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR089W,,YPR090W,Protein of unknown function; exhibits genetic interaction with ERG11 and protein-protein interaction with Hsp82p,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,10,4.5,no,,,,, P133,62,F2,P133_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR092W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,20,8.9,no,,,,, P133,63,F3,P133_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR093C,ASR1,,Ubiquitin ligase that modifies and regulates RNA Pol II; involved in a putative alcohol-responsive signaling pathway; accumulates in the nucleus under alcohol stress; contains a Ring/PHD finger domain similar to the mammalian rA9 protein,"response to chemical stimulus, protein modification process",ligase activity,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, response to chemical stimulus",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,10,5.3,no,,,,, P133,64,F4,P133_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR095C,SYT1,,Guanine nucleotide exchange factor (GEF) for Arf proteins; involved in vesicular transport; suppressor of ypt3 mutations; member of the Sec7-domain family,"transport, vesicle-mediated transport",enzyme regulator activity,"mitochondrion, cytoplasm","enzyme regulator activity, mitochondrion, transport, vesicle-mediated transport",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,22,12.4,no,,,,, P133,65,F5,P133_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR096C,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,14,4.7,no,,,,, P133,66,F6,P133_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR097W,,,"Protein that contains a Phox homology (PX) domain and binds phosphoinositides; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,lipid binding,"mitochondrion, cytoplasm","biological_process, lipid binding, mitochondrion",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,6,3.1,no,,,,, P133,67,F7,P133_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR098C,,,"Protein of unknown function, localized to the mitochondrial outer membrane",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,8,2.5,no,,,,, P133,68,F8,P133_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR099C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MRPL51/YPR100W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,195,14,7.2,no,,,,, P133,69,F9,P133_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR100W,MRPL51,,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation, generation of precursor metabolites and energy, cellular respiration",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, ribosome, structural molecule activity, translation",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,320,2,0.6,no,,,,, P133,70,F10,P133_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR101W,SNT309,NTC25,"Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; interacts physically and genetically with Prp19p",RNA metabolic process,other,nucleus,"RNA metabolic process, nucleus, other, protein binding",,,16_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,331,0,0,no,,,,, P133,71,F11,P133_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL126W,NIT2,,"Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member",biological_process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,22,8.5,no,,,,, P133,72,F12,P133_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL123C,MTC1,,Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1,biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, ribosome, cytoplasm, Golgi apparatus","Golgi apparatus, biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, ribosome",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,3,1.5,no,,,,, P133,73,G1,P133_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL122W,ALB1,,Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p,ribosome biogenesis,molecular_function,"nucleus, ribosome, cytoplasm","cytoplasm, molecular_function, nucleus, organelle organization and biogenesis, ribosome, ribosome biogenesis",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,42,13.9,no,,,,, P133,74,G2,P133_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL120W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL121C/RPE1; deletion confers sensitivity to GSAO",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,8,3.4,no,,,,, P133,75,G3,P133_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL121C,RPE1,POS18;EPI1,"D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress","cofactor metabolic process, cellular carbohydrate metabolic process",isomerase activity,cytoplasm,"carbohydrate metabolic process, cofactor metabolic process, cytoplasm, isomerase activity, vitamin metabolic process",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,231,4,1.7,no,,,,, P133,76,G4,P133_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL118W,,,"Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; YJL18W is a non-essential gene; deletion enhances the toxicity of heterologously expressed human alpha-synuclein",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,6,3.3,no,,,,, P133,77,G5,P133_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL119C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,26,9.4,no,,,,, P133,78,G6,P133_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL117W,PHO86,,"Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles","transport, vesicle-mediated transport, protein folding",protein binding,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, protein binding, protein folding, transport, vesicle-mediated transport",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,4,1.9,no,,,,, P133,79,G7,P133_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL116C,NCA3,,Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family; expression induced in cells treated with the mycotoxin patulin,mitochondrion organization,molecular_function,cellular_component,"cellular_component, molecular_function, organelle organization and biogenesis",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,20,7.3,no,,,,, P133,80,G8,P133_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL115W,ASF1,CIA1,"Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition","response to stress, chromosome organization, transcription, protein modification process, RNA metabolic process",protein binding,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription, transposition",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,24,10.5,no,,,,, P133,81,G9,P133_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL112W,MDV1,NET2;GAG3;FIS2,"Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats","mitochondrion organization, peroxisome organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,7,3.2,no,,,,, P133,82,G10,P133_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL110C,GZF3,NIL2;DEH1,GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p,"transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, nucleus, other, transcription, transcription regulator activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,22,7.7,no,,,,, P133,83,G11,P133_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL108C,PRM10,,"Pheromone-regulated protein, proposed to be involved in mating; predicted to have 5 transmembrane segments; induced by treatment with 8-methoxypsoralen and UVA irradiation",biological_process,molecular_function,membrane,"conjugation, membrane, molecular_function, response to chemical stimulus",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,11,5.4,no,,,,, P133,84,G12,P133_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL107C,,,"Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,18,8.6,no,,,,, P133,85,H1,P133_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL106W,IME2,SME1,"Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p","meiosis, cell cycle, protein modification process","transferase activity, protein kinase activity",nucleus,"cell cycle, meiosis, nucleus, protein kinase activity, protein modification process",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,8,3.2,no,,,,, P133,86,H2,P133_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL100W,LSB6,,"Type II phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization",cellular lipid metabolic process,transferase activity,"membrane, vacuole, plasma membrane, cytoplasm","cytoplasm, lipid metabolic process, membrane, plasma membrane, transferase activity, vacuole",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,9,4.3,no,,,,, P133,87,H3,P133_H3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P133,88,H4,P133_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL099W,CHS6,CSD3,"Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane","transport, cellular carbohydrate metabolic process, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, transport, vesicle-mediated transport",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,9,4.4,no,,,,, P133,89,H5,P133_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL098W,SAP185,,"Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p","cell cycle, RNA metabolic process","phosphoprotein phosphatase activity, hydrolase activity","mitochondrion, cytoplasm","cell cycle, cytoplasm, hydrolase activity, mitochondrion, phosphoprotein phosphatase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,20,7.6,no,,,,, P133,90,H6,P133_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL095W,BCK1,SSP31;SLK1;SAP3;LAS3,"Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p","signaling process, peroxisome organization, response to chemical stimulus, protein modification process, response to stress","transferase activity, protein kinase activity, signal transducer activity",site of polarized growth,"anatomical structure morphogenesis, other, protein kinase activity, protein modification process, response to chemical stimulus, response to stress, signal transducer activity, signal transduction, transferase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,56,19.9,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P133,91,H7,P133_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL093C,TOK1,YPK1;YORK;YKC1;DUK1,"Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin",cellular homeostasis,transporter activity,"membrane, plasma membrane","cellular homeostasis, plasma membrane, transporter activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,16,7.8,no,,,,, P133,92,H8,P133_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL092W,SRS2,HPR5;RADH1;RADH,"DNA helicase and DNA-dependent ATPase involved in DNA repair, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; blocks trinucleotide repeat expansion; affects genome stability","response to stress, DNA metabolic process","helicase activity, hydrolase activity",nucleus,"DNA metabolic process, helicase activity, nucleus, response to stress",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,14,4.2,no,,,,, P133,93,H9,P133_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL089W,SIP4,,C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus,"cellular carbohydrate metabolic process, transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, carbohydrate metabolic process, nucleus, other, transcription, transcription regulator activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,12,4.5,no,,,,, P133,94,H10,P133_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL088W,ARG3,argF,"Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine",cellular amino acid and derivative metabolic process,transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, transferase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,26,8.4,no,,,,, P133,95,H11,P133_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL083W,TAX4,,"EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS","response to stress, fungal-type cell wall organization, signaling process",molecular_function,cytoplasm,"cell wall organization and biogenesis, cytoplasm, molecular_function, other, response to stress, signal transduction",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,7,3.8,no,,,,, P133,96,H12,P133_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL082W,IML2,,"Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"nucleus, membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, nucleus",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,6,2.8,no,,,,, P134,1,A1,P134_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL080C,SCP160,,"Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins","signaling process, transcription, response to chemical stimulus, chromosome segregation, meiosis, conjugation, chromosome organization, cell cycle, RNA metabolic process","RNA binding, protein binding","endomembrane system, membrane, endoplasmic reticulum, cytoplasm","RNA binding, RNA metabolic process, cell cycle, conjugation, cytoplasm, endomembrane system, endoplasmic reticulum, meiosis, membrane, organelle organization and biogenesis, other, protein binding, response to chemical stimulus, signal transduction, transcription",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,22,10.5,no,,,,, P134,2,A2,P134_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL077C,ICS3,,Protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,18,5.3,no,,,,, P134,3,A3,P134_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL073W,JEM1,KAR8,"DnaJ-like chaperone required for nuclear membrane fusion during mating, localizes to the ER membrane; exhibits genetic interactions with KAR2","protein folding, conjugation, cellular protein catabolic process, nucleus organization",protein binding,"membrane fraction, endomembrane system, membrane, endoplasmic reticulum, cytoplasm","conjugation, endomembrane system, endoplasmic reticulum, membrane, membrane fraction, nuclear organization and biogenesis, organelle organization and biogenesis, protein binding, protein catabolic process, protein folding",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,34,10.1,no,,,,, P134,4,A4,P134_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL071W,ARG2,HRB574,"Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p",cellular amino acid and derivative metabolic process,transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, transferase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,42,20.4,no,,,,, P134,5,A5,P134_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL068C,,,"Non-essential intracellular esterase that can function as an S-formylglutathione hydrolase; may be involved in the detoxification of formaldehyde, which can be metabolized to S-formylglutathione; similar to human esterase D",other,hydrolase activity,cytoplasm,"cytoplasm, hydrolase activity, other",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,28,8.6,no,,,,, P134,6,A6,P134_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL067W,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,12,5,no,,,,, P134,7,A7,P134_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL066C,MPM1,,"Mitochondrial membrane protein of unknown function, contains no hydrophobic stretches",biological_process,molecular_function,"membrane fraction, mitochondrion, cytoplasm","biological_process, membrane fraction, mitochondrion, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,12,6.3,no,,,,, P134,8,A8,P134_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL064W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene YJL065C/DLS1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,8,3.8,no,,,,, P134,9,A9,P134_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL065C,DLS1,,"Subunit of ISW2/yCHRAC chromatin accessibility complex along with Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing","transcription, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, transcription",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,17,7.9,no,,,,, P134,10,A10,P134_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL063C,MRPL8,YmL8;HRD238,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, organelle organization and biogenesis, ribosome, structural molecule activity, translation",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,238,15,6.3,no,,,,, P134,11,A11,P134_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL062W,LAS21,GPI7,Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure; mutations affect cell wall integrity,"protein modification process, cellular lipid metabolic process",transferase activity,"endomembrane system, membrane, endoplasmic reticulum, cytoplasm, plasma membrane","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, plasma membrane, protein modification process, transferase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,222,28,12.6,no,,,,, P134,12,A12,P134_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL060W,BNA3,,"Kynurenine aminotransferase, catalyzes formation of kynurenic acid from kynurenine; potential Cdc28p substrate",heterocycle metabolic process,transferase activity,"mitochondrion, cytoplasm","cytoplasm, heterocycle metabolic process, mitochondrion, transferase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,14,4.6,no,,,,, P134,13,B1,P134_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL059W,YHC3,BTN1,Vacuolar membrane protein involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis),"transport, cellular homeostasis",molecular_function,"vacuole, cytoplasm","cellular homeostasis, cytoplasm, molecular_function, transport, vacuole",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,16,5.5,no,,,,, P134,14,B2,P134_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL058C,BIT61,,"Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity","fungal-type cell wall organization, signaling process, cytoskeleton organization",molecular_function,"membrane, plasma membrane, cytoplasm","cell wall organization and biogenesis, cytoplasm, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis, other, signal transduction",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,9,4.8,no,,,,, P134,15,B3,P134_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL057C,IKS1,,Putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,154,28,18.2,no,,,,, P134,16,B4,P134_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL056C,ZAP1,ZRG10,"Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains","transcription, cellular homeostasis, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, cellular homeostasis, nucleus, transcription, transcription regulator activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P134,17,B5,P134_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL055W,,,"Putative protein of unknown function, proposed to be involved in the metabolism of purine and pyrimidine base analogues; deletion mutants are sensitive to HAP and AHA; overexpression confers resistance to 5-FOA and 5-FU",response to chemical stimulus,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, response to chemical stimulus",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,12,7.1,no,,,,, P134,18,B6,P134_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL053W,PEP8,VPT4;VPS26;GRD6,"Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport","transport, vesicle-mediated transport",transporter activity,"membrane, endomembrane system, cytoplasm","cytoplasm, endomembrane system, membrane, other, transport, transporter activity, vesicle-mediated transport",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,22,7.5,no,,,,, P134,19,B7,P134_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL052W,TDH1,GAPDH;GLD3,"Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,"cell wall, membrane fraction, mitochondrion, cytoplasm","carbohydrate metabolic process, cell wall, cytoplasm, generation of precursor metabolites and energy, mitochondrion, oxidoreductase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,52,22.8,no,,,,, P134,20,B8,P134_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL051W,IRC8,,"Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc",DNA metabolic process,molecular_function,cellular bud,"DNA metabolic process, cellular bud, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,54,22.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P134,21,B9,P134_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL049W,,,Putative protein of unknown function; YJL049W is a non-essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,28,11.5,no,,,,, P134,22,B10,P134_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL048C,UBX6,CUI2,"UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline","sporulation resulting in formation of a cellular spore, cellular protein catabolic process",molecular_function,nucleus,"molecular_function, nucleus, protein catabolic process, sporulation",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,0,0,no,,,,, P134,23,B11,P134_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL047C,RTT101,CULLIN 8;CULC;CUL8,"Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex with a role in anaphase progression; implicated in Mms22-dependent DNA repair; involved with Mms1p in nonfunctional rRNA decay; modified by the ubiquitin-like protein, Rub1p","transposition, response to stress, cell cycle, DNA metabolic process, RNA metabolic process, cellular protein catabolic process","ligase activity, protein binding","nucleus, cytoplasm","DNA metabolic process, cell cycle, cytoplasm, ligase activity, nucleus, protein binding, protein catabolic process, transposition",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,91,43.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P134,24,B12,P134_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL046W,AIM22,RRG3;LIP3,"Putative lipoate-protein ligase, required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2p; similar to E. coli LplA; null mutant displays reduced frequency of mitochondrial genome loss",protein modification process,ligase activity,"mitochondrion, cytoplasm","biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,26,9.7,no,,,,, P134,25,C1,P134_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL045W,,SDH1b,"Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner","generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, cytoplasm","cellular respiration, mitochondrion, oxidoreductase activity",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,6,3.3,no,,,,, P134,26,C2,P134_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL044C,GYP6,,"GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport",transport,enzyme regulator activity,"cytoplasmic membrane-bounded vesicle, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, enzyme regulator activity, transport",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,16,7.3,no,,,,, P134,27,C3,P134_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL043W,,,Putative protein of unknown function; YJL043W is a non-essential gene,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,19,9.2,no,,,,, P134,28,C4,P134_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL038C,LOH1,OSW4,Protein of unknown function with proposed roles in maintenance of genome integrity and also in spore wall assembly; induced during sporulation; repressed during vegetative growth by Sum1p and Hst1p; sequence similar to IRC1,chromosome organization,molecular_function,cellular_component,"cellular_component, molecular_function, organelle organization and biogenesis",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,36,15.3,no,,,,, P134,29,C5,P134_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL037W,IRC18,,"Putative protein of unknown function; expression induced in respiratory-deficient cells and in carbon-limited chemostat cultures; similar to adjacent ORF, YJL038C; null mutant displays increased levels of spontaneous Rad52p foci",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,48,17.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P134,30,C6,P134_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL036W,SNX4,ATG24;CVT13,"Sorting nexin, involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p","transport, vesicle-mediated transport, cellular membrane organization",lipid binding,"membrane fraction, cytoplasm","cytoplasm, lipid binding, membrane fraction, membrane organization and biogenesis, transport, vesicle-mediated transport",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,36,13.7,no,,,,, P134,31,C7,P134_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL030W,MAD2,,"Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p","signaling process, chromosome organization, cell cycle",molecular_function,"nucleus, endomembrane system, chromosome, membrane","cell cycle, chromosome, endomembrane system, membrane, molecular_function, nucleus, organelle organization and biogenesis",,,10_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,66,22.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P134,32,C8,P134_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR073C,OPI3,PEM2,"Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis","cellular lipid metabolic process, cellular amino acid and derivative metabolic process",transferase activity,"membrane, membrane fraction, mitochondrion, cytoplasm","endoplasmic reticulum, lipid metabolic process, mitochondrion, transferase activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,2,0.9,no,,,,, P134,33,C9,P134_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR075W,HOC1,,"Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit of a Golgi-localized complex that also contains Anp1p, Mnn9p, Mnn11p, and Mnn10p; identified as a suppressor of a cell lysis sensitive pkc1-371 allele",cellular carbohydrate metabolic process,transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, transferase activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,6,2.5,no,,,,, P134,34,C10,P134_C10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P134,35,C11,P134_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR078W,BNA2,,"Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for de novo biosynthesis of NAD from tryptophan via kynurenine; interacts genetically with telomere capping gene CDC13; regulated by Hst1p and Aftp","cofactor metabolic process, vitamin metabolic process",oxidoreductase activity,cytoplasm,"cofactor metabolic process, cytoplasm, oxidoreductase activity, vitamin metabolic process",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,16,4.8,no,,,,, P134,36,C12,P134_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR079W,,,Putative protein of unknown function; mutation results in impaired mitochondrial respiration,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,172,4,2.3,no,,,,, P134,37,D1,P134_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR082C,EAF6,,Subunit of the NuA4 acetyltransferase complex that acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3,"response to stress, chromosome organization, DNA metabolic process, protein modification process",transferase activity,nucleus,"DNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, response to stress, transferase activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,8,3.3,no,,,,, P134,38,D2,P134_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR083C,ACF4,,"Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in actin cytoskeleton organization; potential Cdc28p substrate",biological_process,molecular_function,cellular_component,"cellular_component, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,2,1.1,no,,,,, P134,39,D3,P134_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR088C,EMC2,,Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response,protein folding,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,4,1.9,no,,,,, P134,40,D4,P134_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR092W,BUD4,,Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate,"cell budding, cytokinesis, cell cycle",other,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, other, site of polarized growth",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,13,6.4,no,,,,, P134,41,D5,P134_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR102C,VPS25,VPL12;VPT25,"Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome","transport, transcription, response to chemical stimulus, cellular protein catabolic process, RNA metabolic process",protein binding,"membrane, cytoplasm","RNA metabolic process, cytoplasm, membrane, protein binding, protein catabolic process, response to chemical stimulus, transcription, transport",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,20,7.8,no,,,,, P134,42,D6,P134_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR103W,URA8,,"Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis","cellular lipid metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",ligase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, ligase activity, lipid metabolic process, other",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,26,12.7,no,,,,, P134,43,D7,P134_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR105W,ADO1,,"Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle","heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, nucleus, transferase activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,2,0.9,no,,,,, P134,44,D8,P134_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR108W,ABM1,,"Protein of unknown function, required for normal microtubule organization",cytoskeleton organization,molecular_function,cellular_component,"cellular_component, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,16,6.5,no,,,,, P134,45,D9,P134_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR110W,YMR1,,"Phosphatidylinositol 3-phosphate (PI3P) phosphatase; involved in various protein sorting pathways, including CVT targeting and endosome to vacuole transport; has similarity to the conserved myotubularin dual specificity phosphatase family",cellular lipid metabolic process,hydrolase activity,cytoplasm,"cytoplasm, hydrolase activity, lipid metabolic process",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,5,2.2,no,,,,, P134,46,D10,P134_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR111C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,29,13.2,no,,,,, P134,47,D11,P134_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR115W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,34,11.1,no,,,,, P134,48,D12,P134_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR127C,RSF2,ZMS1,"Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions",transcription,DNA binding,nucleus,"DNA binding, nucleus, transcription, transcription regulator activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,18,9.4,no,,,,, P134,49,E1,P134_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR128W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSF2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,2,1.3,no,,,,, P134,50,E2,P134_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR129C,,,Putative protein of unknown function; predicted S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,transferase activity,cytoplasm,"biological_process, cytoplasm, transferase activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,8,4.1,no,,,,, P134,51,E3,P134_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR130C,STR2,,"Cystathionine gamma-synthase, converts cysteine into cystathionine",cellular amino acid and derivative metabolic process,transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, other, transferase activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,6,2,no,,,,, P134,52,E4,P134_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR135C,MCM22,,Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner,"chromosome organization, cell cycle, chromosome segregation",protein binding,"nucleus, chromosome","chromosome, nucleus, other, protein binding",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,17,8.9,no,,,,, P134,53,E5,P134_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR137C,MET5,ECM17,"Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine",fungal-type cell wall organization,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cell wall organization and biogenesis, cytoplasm, other, oxidoreductase activity, response to chemical stimulus",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,12,6.7,no,,,,, P134,54,E6,P134_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR146W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene HMS2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,9,4.7,no,,,,, P134,55,E7,P134_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR147W,HMS2,,Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant,pseudohyphal growth,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, pseudohyphal growth",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,12,5.9,no,,,,, P134,56,E8,P134_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR149W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,12,5.8,no,,,,, P134,57,E9,P134_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR152W,DAL5,UREP1,"Allantoate permease; ureidosuccinate permease; also transports dipeptides, though with lower affinity than for allantoate and ureidosuccinate; expression is constitutive but sensitive to nitrogen catabolite repression",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,6,1.8,no,,,,, P134,58,E10,P134_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR154W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,10_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,8,2.9,no,,,,, P134,59,E11,P134_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL012W,UBC8,GID3,"Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro","cellular carbohydrate metabolic process, protein modification process, cellular protein catabolic process",ligase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, ligase activity, protein catabolic process, protein modification process",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,298,8,2.7,no,,,,, P134,60,E12,P134_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER031C,YPT31,YPT8,"Rab family GTPase, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi","transport, vesicle-mediated transport",hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, transport, vesicle-mediated transport",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,2,0.8,no,,,,, P134,61,F1,P134_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER046W,SPO73,,"Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,cytoplasm,"cell wall organization and biogenesis, cytoplasm, molecular_function, sporulation",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,10,5.1,no,,,,, P134,62,F2,P134_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER063W,THO1,,"Conserved nuclear RNA-binding protein; specifically binds to transcribed chromatin in a THO- and RNA-dependent manner, genetically interacts with shuttling hnRNP NAB2; overproduction suppresses transcriptional defect caused by hpr1 mutation","transport, transcription, RNA metabolic process","RNA binding, DNA binding",nucleus,"DNA binding, RNA binding, RNA metabolic process, nucleus, other, transcription, transport",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,10,5.7,no,,,,, P134,63,F3,P134_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER066W,RRT13,,Putative protein of unknown function; non-essential gene identified in a screen for mutants with decreased levels of rDNA transcription,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,4,1.2,no,,,,, P134,64,F4,P134_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR188C,BUB1,,"Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p","signaling process, cytoskeleton organization, protein modification process, chromosome segregation, chromosome organization, cell cycle","transferase activity, protein kinase activity, protein binding","nucleus, chromosome","cell cycle, chromosome, nucleus, protein binding, protein kinase activity, protein modification process",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,6,2.9,no,,,,, P134,65,F5,P134_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR201C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,6,2.8,no,,,,, P134,66,F6,P134_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR204W,ADE3,,"Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine; null mutation causes auxotrophy for adenine and histidine","cofactor metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process","ligase activity, hydrolase activity, oxidoreductase activity","nucleus, cytoplasm","aromatic compound metabolic process, cofactor metabolic process, cytoplasm, heterocycle metabolic process, hydrolase activity, ligase activity, nucleus, oxidoreductase activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,2,1.3,no,,,,, P134,67,F7,P134_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL002W,HSE1,,"Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes","transport, vesicle-mediated transport",protein binding,cytoplasm,"cytoplasm, protein binding, transport, vesicle-mediated transport",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,4,1.8,no,,,,, P134,68,F8,P134_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL011C,PRS3,,"5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes","fungal-type cell wall organization, cellular carbohydrate metabolic process, heterocycle metabolic process",transferase activity,cytoplasm,"carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, other, ribosome biogenesis, transferase activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,140,4,2.9,no,,,,, P134,69,F9,P134_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL039W,EFM1,,Probable lysine methyltransferase involved in the monomethylation of eEF1A (Tef1p/Tef2p); SET-domain family member; predicted involvement in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,protein modification process,transferase activity,cytoplasm,"cytoplasm, molecular_function, ribosome biogenesis",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,2,1,no,,,,, P134,70,F10,P134_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR003C,,,"Protein of unknown function, localized to the mitochondrial outer membrane",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,1,0.6,no,,,,, P134,71,F11,P134_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR004C,NEM1,,"Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard","sporulation resulting in formation of a cellular spore, cellular membrane organization, nucleus organization","hydrolase activity, phosphoprotein phosphatase activity","endomembrane system, mitochondrion, membrane, cytoplasm","endomembrane system, membrane, mitochondrion, nuclear organization and biogenesis, phosphoprotein phosphatase activity, sporulation",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,204,6,2.9,no,,,,, P134,72,F12,P134_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR005C,GPA1,SCG1;DAC1;CDC70,GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome,"transport, signaling process, heterocycle metabolic process, response to chemical stimulus, conjugation, nucleus organization",hydrolase activity,"membrane, cytoplasm, plasma membrane","conjugation, cytoplasm, hydrolase activity, membrane, plasma membrane, response to chemical stimulus, signal transduction",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P134,73,G1,P134_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR006W,STP2,,"Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes","transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,0,0,no,,,,, P134,74,G2,P134_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR008C,SOD2,,"Mitochondrial superoxide dismutase, protects cells against oxygen toxicity; phosphorylated","response to stress, response to chemical stimulus",oxidoreductase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,0,0,no,,,,, P134,75,G3,P134_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR009C,,,Putative protein of unknown function; not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,256,8,3.1,no,,,,, P134,76,G4,P134_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR025W,THR1,,"Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway",cellular amino acid and derivative metabolic process,transferase activity,cellular_component,"amino acid and derivative metabolic process, cellular_component, transferase activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,2,0.7,no,,,,, P134,77,G5,P134_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR026W,PPA1,VMA16,"Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, response to chemical stimulus, transporter activity, vacuole",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,4,2.1,no,,,,, P134,78,G6,P134_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR041C,SRB2,MED20;HRS2,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance,"transcription, response to chemical stimulus, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,2,0.9,no,,,,, P134,79,G7,P134_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR059W,FYV4,,"Protein of unknown function, required for survival upon exposure to K1 killer toxin",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,2,0.6,no,,,,, P134,80,G8,P134_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR067W,HTD2,RMD12,"Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology",cellular lipid metabolic process,lyase activity,"mitochondrion, cytoplasm","lipid metabolic process, lyase activity, mitochondrion",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,6,1.9,no,,,,, P134,81,G9,P134_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR127W,,HSN1,Protein of unknown function; localizes to the nucleus; required for asymmetric localization of Kar9p during mitosis,"cytoskeleton organization, cell cycle",molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,1,0.6,no,,,,, P134,82,G10,P134_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR131C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; overexpression causes a cell cycle delay or arrest,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,2,1.1,no,,,,, P134,83,G11,P134_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR180W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,2,0.9,no,,,,, P134,84,G12,P134_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR185C,PFS1,ADY1,"Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,cellular_component,"cell wall organization and biogenesis, cellular_component, molecular_function, sporulation",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,8,3.7,no,,,,, P134,85,H1,P134_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR194W,MDM31,,"Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34","mitochondrion organization, cellular homeostasis",molecular_function,"nucleus, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular homeostasis, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, nucleus, organelle organization and biogenesis",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,19,10.6,no,,,,, P134,86,H2,P134_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL007C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL007C is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,4,1.7,no,,,,, P134,87,H3,P134_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P134,88,H4,P134_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR154C,RIM13,CPL1,Calpain-like cysteine protease involved in proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans palB,other,"peptidase activity, hydrolase activity",cellular_component,"cellular_component, hydrolase activity, peptidase activity, protein modification process",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,4,2,no,,,,, P134,89,H5,P134_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL274C,GOR1,,"Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",other,oxidoreductase activity,"nucleus, mitochondrion, cytoplasm","cytoplasm, mitochondrion, nucleus, other, oxidoreductase activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,2,1,no,,,,, P134,90,H6,P134_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL141W,PPM2,TYW4,"AdoMet-dependent tRNA methyltransferase also involved in methoxycarbonylation; required for the synthesis of wybutosine (yW), a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA; similarity to Ppm1p",RNA metabolic process,transferase activity,"mitochondrion, cytoplasm","RNA metabolic process, cytoplasm, mitochondrion, transferase activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,2,1.1,no,,,,, P134,91,H7,P134_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL150C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,8,3.8,no,,,,, P134,92,H8,P134_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL158C,ENB1,ARN4,"Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment","transport, cellular homeostasis",transporter activity,"cellular bud, membrane, plasma membrane","cellular homeostasis, cytoplasm, cytoplasmic membrane-bounded vesicle, membrane, transport, transporter activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,14,5.4,no,,,,, P134,93,H9,P134_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL159C,,,Soluble protein of unknown function; deletion mutants are viable and have elevated levels of Ty1 retrotransposition and Ty1 cDNA,biological_process,molecular_function,other,"biological_process, molecular_function, other",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,3,1.8,no,,,,, P134,94,H10,P134_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL160W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,4,2.4,no,,,,, P134,95,H11,P134_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL162W,,,Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family,transport,transporter activity,membrane,"membrane, transport, transporter activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,20,6,no,,,,, P134,96,H12,P134_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL163W,,,Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family,transport,transporter activity,membrane,"membrane, transport, transporter activity",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,7,4.1,no,,,,, P135,1,A1,P135_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR008C-A,,,"Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_10,,,,DIC:cell structure;YFP:Rad52-YFP protein,,150,14,9.3,no,,,,, P135,2,A2,P135_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR087C,OMA1,,"Metalloendopeptidase of the mitochondrial inner membrane, involved in turnover of membrane-embedded proteins; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes",cellular protein catabolic process,"peptidase activity, hydrolase activity","membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, peptidase activity, protein catabolic process",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,18,7.7,no,,,,, P135,3,A3,P135_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR088C,TVP38,,Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; required for asymmetric localization of Kar9p during mitosis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern,"transport, vesicle-mediated transport, cytoskeleton organization, cell cycle",molecular_function,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, membrane, molecular_function, vesicle-mediated transport",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,2,1,no,,,,, P135,4,A4,P135_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR089C,TGL4,STC1,"Multifunctional triacylglycerol lipase, steryl ester hydrolase, and Ca2+-independent phospholipase A2; catalyzes acyl-CoA dependent acylation of LPA to PA; required with Tgl3p for timely bud formation; phosphorylated and activated by Cdc28p","cell budding, cellular lipid metabolic process","transferase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, lipid metabolic process",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,4,2.8,no,,,,, P135,5,A5,P135_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR090W,PXL1,,"LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin",other,protein binding,"cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cellular bud, cytoplasm, other, protein binding, site of polarized growth",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,6,2.1,no,,,,, P135,6,A6,P135_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR091W,SRL3,,"Cytoplasmic protein that, when overexpressed, suppresses the lethality of a rad53 null mutation; potential Cdc28p substrate",other,molecular_function,cytoplasm,"cytoplasm, molecular_function, other",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,0,0,no,,,,, P135,7,A7,P135_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR092C,SRP40,,"Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140",transport,molecular_function,"nucleus, nucleolus","molecular_function, nucleolus, ribosome biogenesis, transport",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,5,2.7,no,,,,, P135,8,A8,P135_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR093W,PTR2,,"Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p",transport,transporter activity,"membrane, membrane fraction, plasma membrane","membrane fraction, plasma membrane, transport, transporter activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,243,3,1.2,no,,,,, P135,9,A9,P135_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR097W,PCK1,PPC1;JPM2,"Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol",cellular carbohydrate metabolic process,lyase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, lyase activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,28,11,no,,,,, P135,10,A10,P135_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR098C,UBP11,,Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins,biological_process,"peptidase activity, hydrolase activity",cellular_component,"biological_process, cellular_component, hydrolase activity, peptidase activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,9,3.8,no,,,,, P135,11,A11,P135_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR099W,BAS1,,Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes,"transcription, cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process, meiosis, cell cycle, DNA metabolic process, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, RNA metabolic process, amino acid and derivative metabolic process, aromatic compound metabolic process, cell cycle, heterocycle metabolic process, meiosis, nucleus, transcription, transcription regulator activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,6,4.2,no,,,,, P135,12,A12,P135_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR100C,SKG1,YKR099C-A,Transmembrane protein with a role in cell wall polymer composition; localizes on the inner surface of the plasma membrane at the bud and in the daughter cell,fungal-type cell wall organization,molecular_function,"cellular bud, site of polarized growth","cell wall organization and biogenesis, cellular bud, molecular_function, other, site of polarized growth",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,7,3.3,no,,,,, P135,13,B1,P135_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR101W,SIR1,,"Protein involved in repression of transcription at the silent mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin","chromosome organization, transcription, RNA metabolic process",DNA binding,nucleus,"DNA binding, RNA metabolic process, nucleus, organelle organization and biogenesis, other, transcription",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,0,0,no,,,,, P135,14,B2,P135_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR103W,NFT1,,Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds.,transport,"transporter activity, hydrolase activity",membrane,"hydrolase activity, membrane, transport, transporter activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,7,3.9,no,,,,, P135,15,B3,P135_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR104W,,NFT1,Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; contains a stop codon in S288C; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds,transport,"transporter activity, hydrolase activity",membrane,"hydrolase activity, membrane, transport, transporter activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,12,6.3,no,,,,, P135,16,B4,P135_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR105C,VBA5,,Putative transporter of the Major Facilitator Superfamily (MFS); proposed role as a basic amino acid permease based on phylogeny,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,0,0,no,,,,, P135,17,B5,P135_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL018C-A,COX19,,"Protein required for cytochrome c oxidase assembly, located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs","transport, mitochondrion organization, protein complex biogenesis",other,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, transport",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,172,5,2.9,no,,,,, P135,18,B6,P135_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR262C-A,TMA7,RBF7,"Protein of unknown that associates with ribosomes; null mutant exhibits translation defects, altered polyribosome profiles, and resistance to the translation inhibitor anisomcyin",translation,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, translation",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,2,0.9,no,,,,, P135,19,B7,P135_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR422W,,,"Protein of unknown function with similarity to human DOCK proteins (guanine nucleotide exchange factors); interacts with Ino4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, YLR422W is not an essential protein",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,34,12.6,no,,,,, P135,20,B8,P135_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR423C,ATG17,APG17,Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity,"vacuole organization, peroxisome organization, response to stress, cellular membrane organization","enzyme regulator activity, structural molecule activity, protein binding",cytoplasm,"cytoplasm, enzyme regulator activity, membrane organization and biogenesis, organelle organization and biogenesis, other, protein binding, response to stress",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,21,11.3,no,,,,, P135,21,B9,P135_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR425W,TUS1,SOP10,Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate,"fungal-type cell wall organization, signaling process",enzyme regulator activity,cellular_component,"cell wall organization and biogenesis, cellular_component, enzyme regulator activity, signal transduction",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,12,4.7,no,,,,, P135,22,B10,P135_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR426W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin",response to chemical stimulus,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, response to chemical stimulus",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,6,3.8,no,,,,, P135,23,B11,P135_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR427W,MAG2,,Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1,biological_process,molecular_function,cytoplasm,"DNA metabolic process, cytoplasm, molecular_function, response to stress",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,20,6.9,no,,,,, P135,24,B12,P135_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR428C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CRN1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,2,0.6,no,,,,, P135,25,C1,P135_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR429W,CRN1,,"Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity; plays a role in regulation of actin patch assembly","cytoskeleton organization, protein complex biogenesis",protein binding,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,1,0.5,no,,,,, P135,26,C2,P135_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR431C,ATG23,CVT23,Peripheral membrane protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway and efficient macroautophagy; cycles between the phagophore assembly site (PAS) and non-PAS locations; forms a complex with Atg9p and Atg27p,"transport, response to stress",molecular_function,"membrane fraction, cytoplasm","cytoplasm, membrane fraction, molecular_function, other, response to stress, transport",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,2,1.1,no,,,,, P135,27,C3,P135_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR432W,IMD3,,"Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed",heterocycle metabolic process,oxidoreductase activity,"membrane fraction, cytoplasm","cytoplasm, other, oxidoreductase activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,6,3.4,no,,,,, P135,28,C4,P135_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR433C,CNA1,CMP1,"Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1","fungal-type cell wall organization, conjugation, cellular homeostasis, response to chemical stimulus","phosphoprotein phosphatase activity, hydrolase activity",cytoplasm,"cell wall organization and biogenesis, cellular homeostasis, conjugation, cytoplasm, hydrolase activity, other, phosphoprotein phosphatase activity, response to chemical stimulus, signal transduction",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,0,0,no,,,,, P135,29,C5,P135_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR434C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF TSR2/YLR435W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,6,1.8,no,,,,, P135,30,C6,P135_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR436C,ECM30,,Non-essential protein of unknown function,fungal-type cell wall organization,molecular_function,cytoplasm,"cell wall organization and biogenesis, cytoplasm, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,8,4.5,no,,,,, P135,31,C7,P135_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR437C,DIF1,,Protein that regulates the nuclear localization of ribonucleotide reductase Rnr2p and Rnr4p subunits; phosphorylated by Dun1p in response to DNA damage and degraded; N-terminal half has similarity to S. pombe Spd1 protein,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,18,8.4,no,,,,, P135,32,C8,P135_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR438W,CAR2,cargB,"L-ornithine transaminase (OTAse), catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive",cellular amino acid and derivative metabolic process,transferase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, nucleus, transferase activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,22,8.4,no,,,,, P135,33,C9,P135_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR441C,RPS1A,rp10A;S1A;RP10A,Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,4,2.1,no,,,,, P135,34,C10,P135_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR443W,ECM7,ZRG15,Non-essential putative integral membrane protein; mutant has cell wall defects; transcription is induced under conditions of zinc deficiency,fungal-type cell wall organization,molecular_function,membrane,"cell wall organization and biogenesis, membrane, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,28,10.5,no,,,,, P135,35,C11,P135_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P135,36,C12,P135_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR444C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,10,3.2,no,,,,, P135,37,D1,P135_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR445W,,,Putative protein of unknown function; transcription is regulated by Ume6p and induced in response to alpha factor,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,3,1.1,no,,,,, P135,38,D2,P135_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR446W,,,Putative protein of unknown function with similarity to hexokinases; transcript is upregulated during sporulation and the unfolded protein response; YLR446W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,8,3.7,no,,,,, P135,39,D3,P135_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR447C,VMA6,,"Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found in the endomembrane system; stabilizes VO subunits; required for V1 domain assembly on the vacuolar membrane","transport, cellular homeostasis","transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transport, transporter activity, vacuole",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,14,6.8,no,,,,, P135,40,D4,P135_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR448W,RPL6B,rp18;YL16;L6B;L17B,"Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA","translation, ribosome biogenesis","RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,4,1.6,no,,,,, P135,41,D5,P135_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR449W,FPR4,,"Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones","transcription, protein modification process, chromosome organization, RNA metabolic process","isomerase activity, protein binding","nucleus, chromosome","RNA metabolic process, chromosome, isomerase activity, nucleus, organelle organization and biogenesis, protein binding, protein modification process, ribosome biogenesis, transcription",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,24,7.1,no,,,,, P135,42,D6,P135_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR450W,HMG2,,"One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks",other,oxidoreductase activity,"nucleus, membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, mitochondrion, nucleus, oxidoreductase activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,24,9.3,no,,,,, P135,43,D7,P135_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR452C,SST2,,"GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family","signaling process, conjugation, response to chemical stimulus",enzyme regulator activity,"membrane, plasma membrane","conjugation, enzyme regulator activity, plasma membrane, response to chemical stimulus, signal transduction",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,183,6,3.3,no,,,,, P135,44,D8,P135_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR453C,RIF2,,Protein that binds to the Rap1p C-terminus and acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation,"chromosome organization, DNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, chromosome, nucleus, organelle organization and biogenesis",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,18,5.4,no,,,,, P135,45,D9,P135_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR454W,FMP27,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,10,5.4,no,,,,, P135,46,D10,P135_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR456W,,,"Putative protein of unknown function; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,0,0,no,,,,, P135,47,D11,P135_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR460C,,,"Member of the quinone oxidoreductase family, up-regulated in response to the fungicide mancozeb; possibly up-regulated by iodine",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,8,2.9,no,,,,, P135,48,D12,P135_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR461W,PAU4,,"Member of the seripauperin multigene family encoded mainly in subtelomeric regions; active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,5,2.8,no,,,,, P135,49,E1,P135_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML009C,MRPL39,YmL39,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,3,1.6,no,,,,, P135,50,E2,P135_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML009C-A,,YML010W-B;YML010C-B,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,30,12,no,,,,, P135,51,E3,P135_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML021C,UNG1,,"Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus","response to stress, DNA metabolic process",hydrolase activity,"nucleus, mitochondrion, cytoplasm","DNA metabolic process, hydrolase activity, mitochondrion, nucleus, response to stress",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,4,1.3,no,,,,, P135,52,E4,P135_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML081C-A,ATP18,,"Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms","transport, heterocycle metabolic process",transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,14,5.2,no,,,,, P135,53,E5,P135_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR060C,SAM37,TOM37;PET3027;MAS37,"Component of the Sorting and Assembly Machinery (SAM or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; contributes to SAM complex stability","transport, mitochondrion organization, protein complex biogenesis, cellular membrane organization",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, protein binding",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,50,16.6,no,,,,, P135,54,E6,P135_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR158C-A,,YMR158C-B,"Putative protein of unknown function, may contain a lipid attachment site; YMR158C-A is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,8,2.5,no,,,,, P135,55,E7,P135_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR169C,ALD3,,"Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose",cellular amino acid and derivative metabolic process,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, oxidoreductase activity, response to stress",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,4,1.7,no,,,,, P135,56,E8,P135_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR174C,PAI3,IA3,"Cytoplasmic proteinase A (Pep4p) inhibitor, dependent on Pbs2p and Hog1p protein kinases for osmotic induction; intrinsically unstructured, N-terminal half becomes ordered in the active site of proteinase A upon contact",cellular protein catabolic process,enzyme regulator activity,cytoplasm,"cytoplasm, enzyme regulator activity, protein catabolic process",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,0,0,no,,,,, P135,57,E9,P135_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR175W,SIP18,,Phospholipid-binding protein; expression is induced by osmotic stress,biological_process,lipid binding,other,"lipid binding, other, response to stress",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,10,5,no,,,,, P135,58,E10,P135_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR194C-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,20,6.4,no,,,,, P135,59,E11,P135_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR326C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the telomere on the right arm of chromosome 13",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,7,3.6,no,,,,, P135,60,E12,P135_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR032C-A,HUB1,,"Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear","conjugation, cellular component morphogenesis, response to chemical stimulus, protein modification process, RNA metabolic process",other,other,"RNA metabolic process, anatomical structure morphogenesis, conjugation, other, protein modification process, response to chemical stimulus",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,2,0.6,no,,,,, P135,61,F1,P135_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR050C,LYS9,LYS13,"Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, the seventh step in lysine biosynthesis pathway; exhibits genetic and physical interactions with TRM112",cellular amino acid and derivative metabolic process,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, oxidoreductase activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,1,0.5,no,,,,, P135,62,F2,P135_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR051C,BRE5,,"Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A","transport, vesicle-mediated transport, protein modification process",molecular_function,cytoplasm,"cytoplasm, molecular_function, other, protein modification process",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,4,1.4,no,,,,, P135,63,F3,P135_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR056C,BIO5,,"Putative transmembrane protein involved in the biotin biosynthesis pathway; responsible for uptake of 7-keto 8-aminopelargonic acid; BIO5 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis","transport, cofactor metabolic process, vitamin metabolic process, heterocycle metabolic process",transporter activity,"membrane, plasma membrane","cofactor metabolic process, heterocycle metabolic process, plasma membrane, transport, transporter activity, vitamin metabolic process",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,4,1.4,no,,,,, P135,64,F4,P135_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR057C,BIO4,,"Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels","cofactor metabolic process, vitamin metabolic process, heterocycle metabolic process",ligase activity,cytoplasm,"cofactor metabolic process, cytoplasm, heterocycle metabolic process, ligase activity, vitamin metabolic process",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,4,1.8,no,,,,, P135,65,F5,P135_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR058W,BIO3,,"7,8-diamino-pelargonic acid aminotransferase (DAPA), catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis","cofactor metabolic process, vitamin metabolic process, heterocycle metabolic process",transferase activity,cytoplasm,"cofactor metabolic process, cytoplasm, heterocycle metabolic process, transferase activity, vitamin metabolic process",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,2,0.9,no,,,,, P135,66,F6,P135_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR059W,MNT4,,"Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation","cellular carbohydrate metabolic process, protein modification process",transferase activity,cellular_component,"cellular_component, protein modification process, transferase activity",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,2,1.1,no,,,,, P135,67,F7,P135_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR060W,FRE4,,"Ferric reductase, reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels","transport, cellular homeostasis",oxidoreductase activity,"membrane, plasma membrane","cellular homeostasis, oxidoreductase activity, plasma membrane, transport",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,0,0,no,,,,, P135,68,F8,P135_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR061C,,,Putative protein of unknown function,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,1,0.4,no,,,,, P135,69,F9,P135_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR062C,,,Putative membrane protein of unknown function,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,2,0.9,no,,,,, P135,70,F10,P135_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR063W,,,Putative zinc-cluster protein of unknown function,biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,3,1.6,no,,,,, P135,71,F11,P135_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR064C,,,"Epoxide hydrolase, member of the alpha/beta hydrolase fold family; may have a role in detoxification of epoxides",response to chemical stimulus,hydrolase activity,other,"hydrolase activity, other, response to chemical stimulus",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,2,0.9,no,,,,, P135,72,F12,P135_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR065C,,YSN1,Protein of unknown function; protein-protein interactions suggest a possible role in actin patch formation; YNR065C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,5,2.4,no,,,,, P135,73,G1,P135_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR066C,,,Putative membrane-localized protein of unknown function,biological_process,molecular_function,membrane fraction,"biological_process, membrane fraction, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,0,0,no,,,,, P135,74,G2,P135_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR067C,DSE4,ENG1,"Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother",cytokinesis,hydrolase activity,"cell wall, extracellular region","cell wall, cytokinesis, extracellular region, hydrolase activity, other",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,2,1,no,,,,, P135,75,G3,P135_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR068C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,4,1.2,no,,,,, P135,76,G4,P135_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAL012W,CYS3,STR1;FUN35;CYI1,"Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine",cellular amino acid and derivative metabolic process,lyase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, lyase activity, response to chemical stimulus",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,2,0.7,no,,,,, P135,77,G5,P135_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAL047C,SPC72,LDB4,"Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them to microtubules; has roles in astral microtubule formation and stabilization","transport, signaling process, cytoskeleton organization, chromosome segregation, chromosome organization, cell cycle",structural molecule activity,"cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, organelle organization and biogenesis, structural molecule activity, transport",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,4,2.1,no,,,,, P135,78,G6,P135_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAL054C,ACS1,FUN44,"Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions","cofactor metabolic process, chromosome organization, generation of precursor metabolites and energy, protein modification process",ligase activity,"mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, ligase activity, mitochondrion, organelle organization and biogenesis, protein modification process",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,16,11.3,no,,,,, P135,79,G7,P135_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAL056C-A,,YAL058C-A,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,251,2,0.8,no,,,,, P135,80,G8,P135_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAR050W,FLO1,FLO4;FLO2,"Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p",response to stress,other,cell wall,"cell wall, other",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,0,0,no,,,,, P135,81,G9,P135_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL006C,,,,,,,,,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,17,8.8,no,,,,, P135,82,G10,P135_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL022C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene KCC4/YCL024W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,233,2,0.9,no,,,,, P135,83,G11,P135_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL023C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,187,22,11.8,no,,,,, P135,84,G12,P135_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL038C,ATG22,AUT4,Vacuolar integral membrane protein required for efflux of amino acids during autophagic body breakdown in the vacuole; null mutation causes a gradual loss of viability during starvation,transport,molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, membrane, molecular_function, transport, vacuole",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,209,12,5.7,no,,,,, P135,85,H1,P135_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL058C,FYV5,MDF1,Protein involved in regulation of the mating pathway; binds with Matalpha2p to promoters of haploid-specific genes; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis,"signaling process, conjugation, cellular homeostasis, response to chemical stimulus",molecular_function,cellular_component,"cellular homeostasis, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,324,18,5.6,no,,,,, P135,86,H2,P135_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL074W,,,,,,,,,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,231,6,2.6,no,,,,, P135,87,H3,P135_H3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P135,88,H4,P135_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL075W,,,,,,,,,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,193,13,6.7,no,,,,, P135,89,H5,P135_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL076W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,267,20,7.5,no,,,,, P135,90,H6,P135_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL199C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YIP4/YGL198W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,0,0,no,,,,, P135,91,H7,P135_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL214W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; deletion mutation phenotype is likely due to the overlapping verified ORF SKI8/YGL213C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,10,3.3,no,,,,, P135,92,H8,P135_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL217C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF KIP3/YGL216W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,3,1.3,no,,,,, P135,93,H9,P135_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL235W,,,"Putative protein of unknown function; potential Cdc28p substrate; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,10,5.5,no,,,,, P135,94,H10,P135_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR011W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,4,1.9,no,,,,, P135,95,H11,P135_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR018C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YGR017W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,5,2.6,no,,,,, P135,96,H12,P135_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR022C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF MTL1/YGR023W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,10,3.2,no,,,,, P136,1,A1,P136_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR025W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,6,2.9,no,,,,, P136,2,A2,P136_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR069C,HAM1,,"Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine",response to stress,hydrolase activity,"nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, other, response to stress",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,32,13.6,no,,,,, P136,3,A3,P136_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR070C,LIA1,MMD1,"Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning","cytoskeleton organization, cellular amino acid and derivative metabolic process, protein modification process",oxidoreductase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, cytoskeleton organization and biogenesis, nucleus, organelle organization and biogenesis, oxidoreductase activity, protein binding, protein modification process, ribosome biogenesis",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,16,8.8,no,,,,, P136,4,A4,P136_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR074W,MOG1,,"Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase family, and stimulates nucleotide release, involved in nuclear protein import, nucleotide release is inhibited by Yrb1p",transport,protein binding,nucleus,"nucleus, protein binding, transport",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,8,2.8,no,,,,, P136,5,A5,P136_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR077C,MIR1,,"Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated",transport,transporter activity,"mitochondrial envelope, mitochondrion, cytoplasm","mitochondrial envelope, mitochondrion, transport, transporter activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,10,3.1,no,,,,, P136,6,A6,P136_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR080C,AIM24,FMP26,"Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays reduced respiratory growth and elevated frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,12,5,no,,,,, P136,7,A7,P136_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR084W,CSN12,,"Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in mRNA splicing and adaptation to pheromone signaling","conjugation, response to chemical stimulus, RNA metabolic process",molecular_function,nucleus,"conjugation, molecular_function, nucleus, response to chemical stimulus, signal transduction",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,12,6.6,no,,,,, P136,8,A8,P136_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR087W,,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene STE18 and uncharacterized ORF YJR088C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,20,9,no,,,,, P136,9,A9,P136_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR090C,GRR1,SDC1;SSU2;COT2;CAT80,"F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification","response to chemical stimulus, protein modification process, response to stress, conjugation, cell cycle, cellular protein catabolic process","ligase activity, protein binding","nucleus, cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","cell cortex, cell cycle, cellular bud, conjugation, cytoplasm, cytoskeleton, ligase activity, nucleus, other, protein binding, protein catabolic process, protein modification process, response to chemical stimulus, response to stress, site of polarized growth",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,14,7.4,no,,,,, P136,10,A10,P136_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR091C,JSN1,PUF1,"Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl",RNA metabolic process,RNA binding,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","RNA binding, RNA metabolic process, cellular_component",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,20,6.3,no,,,,, P136,11,A11,P136_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR094C,IME1,,"Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p","meiosis, cell cycle",transcription regulator activity,nucleus,"meiosis, nucleus, transcription regulator activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,10,3.5,no,,,,, P136,12,A12,P136_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR094W-A,RPL43B,L43B,"Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,19,9.3,no,,,,, P136,13,B1,P136_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR095W,SFC1,ACR1,"Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,20,11.8,no,,,,, P136,14,B2,P136_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR096W,,,Putative xylose and arabinose reductase; member of the aldo-keto reductase (AKR) family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS,"response to stress, cellular carbohydrate metabolic process, response to chemical stimulus",oxidoreductase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,24,8.7,no,,,,, P136,15,B3,P136_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR097W,JJJ3,DPH4,"Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein",protein modification process,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, protein modification process",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,2,0.7,no,,,,, P136,16,B4,P136_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR098C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,15,7.3,no,,,,, P136,17,B5,P136_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR099W,YUH1,,Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p,protein modification process,"peptidase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, peptidase activity, protein modification process",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,13,5.6,no,,,,, P136,18,B6,P136_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR100C,AIM25,,Putative protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; similar to murine NOR1; null mutant is viable and displays elevated frequency of mitochondrial genome loss,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,16,8.9,no,,,,, P136,19,B7,P136_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR104C,SOD1,CRS4,Cytosolic copper-zinc superoxide dismutase; some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans,"fungal-type cell wall organization, transcription, response to chemical stimulus, response to stress, cellular homeostasis",oxidoreductase activity,"nucleus, mitochondrion, mitochondrial envelope, cytoplasm","cellular homeostasis, cytoplasm, mitochondrial envelope, mitochondrion, other, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,202,4,2,no,,,,, P136,20,B8,P136_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR106W,ECM27,,Non-essential protein of unknown function,fungal-type cell wall organization,molecular_function,cellular_component,"cell wall organization and biogenesis, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,27,13,no,,,,, P136,21,B9,P136_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR107W,,,Putative protein of unknown function; has sequence or structural similarity to lipases,biological_process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,243,15,6.2,no,,,,, P136,22,B10,P136_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR109C,CPA2,,"Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor",cellular amino acid and derivative metabolic process,ligase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, ligase activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,8,4.1,no,,,,, P136,23,B11,P136_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR113C,RSM7,,"Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,312,4,1.3,no,,,,, P136,24,B12,P136_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR116W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,20,6.7,no,,,,, P136,25,C1,P136_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR117W,STE24,PIO2;AFC1,"Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans",other,"peptidase activity, hydrolase activity","nucleus, endomembrane system, mitochondrion, membrane, mitochondrial envelope, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, peptidase activity, protein modification process",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,19,10.7,no,,,,, P136,26,C2,P136_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR118C,ILM1,,Protein of unknown function; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth,mitochondrion organization,molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, organelle organization and biogenesis",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,402,4,1,no,,,,, P136,27,C3,P136_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR119C,JHD2,KDM5;KDM5,JmjC domain family histone demethylase specific for H3-K4 (histone H3 Lys4); removes methyl groups specifically added by Set1p methyltransferase; protein levels regulated by Not4p (E3 ubiquitin ligase) polyubiquitin-mediated degradation,"chromosome organization, protein modification process",other,"nucleus, cytoplasm","cytoplasm, nucleus, organelle organization and biogenesis, other, protein modification process",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,180,2,1.1,no,,,,, P136,28,C4,P136_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR120W,,,"Protein of unknown function; essential for growth under anaerobic conditions; mutation causes decreased expression of ATP2, impaired respiration, defective sterol uptake, and altered levels/localization of ABC transporters Aus1p and Pdr11p","transport, mitochondrion organization, generation of precursor metabolites and energy, cellular respiration",molecular_function,cellular_component,"cellular respiration, cellular_component, molecular_function, organelle organization and biogenesis, transport",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,231,18,7.8,no,,,,, P136,29,C5,P136_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR121W,ATP2,,"Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated","transport, heterocycle metabolic process","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,3,1.6,no,,,,, P136,30,C6,P136_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR122W,IBA57,CAF17,Mitochondrial matrix protein involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins; activates the radical-SAM family members Bio2p and Lip5p; interacts with Ccr4p in the two-hybrid system,cofactor metabolic process,molecular_function,"mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, mitochondrion, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,64,21.3,no,,,,, P136,31,C7,P136_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR124C,,,Putative protein of unknown function; expression induced under calcium shortage,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,1,0.6,no,,,,, P136,32,C8,P136_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR125C,ENT3,,Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p,"transport, cytoskeleton organization, vesicle-mediated transport, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, endomembrane system, cytoplasmic membrane-bounded vesicle, membrane, cytoplasm","cell cortex, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton, cytoskeleton organization and biogenesis, endomembrane system, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,5,2.3,no,,,,, P136,33,C9,P136_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR126C,VPS70,,Protein of unknown function involved in vacuolar protein sorting,transport,molecular_function,cellular_component,"cellular_component, molecular_function, transport",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,40,13.3,no,,,,, P136,34,C10,P136_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR131W,MNS1,,"Alpha-1,2-mannosidase involved in ER quality control; catalyzes the removal of one mannose residue from Man9GlcNAc to produce a single isomer of Man8GlcNAc in N-linked oligosaccharide biosynthesis; integral to ER membrane","cellular carbohydrate metabolic process, protein modification process, cellular protein catabolic process",hydrolase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, protein catabolic process, protein modification process",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,36,11.5,no,,,,, P136,35,C11,P136_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR133W,XPT1,,"Xanthine-guanine phosphoribosyl transferase, required for xanthine utilization and for optimal utilization of guanine","heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, other, transferase activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,3,1.2,no,,,,, P136,36,C12,P136_C12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P136,37,D1,P136_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR134C,SGM1,,"Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus",biological_process,molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, biological_process, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,26,11.1,no,,,,, P136,38,D2,P136_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR139C,HOM6,,"Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions",cellular amino acid and derivative metabolic process,oxidoreductase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,36,21.4,no,,,,, P136,39,D3,P136_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR140C,HIR3,HPC1,"Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly","transcription, chromosome organization, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding, protein binding",nucleus,"DNA binding, RNA metabolic process, cell cycle, nucleus, organelle organization and biogenesis, other, protein binding, transcription, transcription regulator activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,12,4.1,no,,,,, P136,40,D4,P136_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR142W,,,Putative protein of unknown function; GST fusion protein is a Dbf2-Mob1 phosphoylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,30,11.5,no,,,,, P136,41,D5,P136_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR144W,MGM101,MGM9,"Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage","response to stress, mitochondrion organization, DNA metabolic process",DNA binding,"chromosome, mitochondrion, cytoplasm","DNA binding, DNA metabolic process, chromosome, cytoplasm, mitochondrion, organelle organization and biogenesis, response to stress",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,16,5.6,no,,,,, P136,42,D6,P136_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR145C,RPS4A,rp5;YS6;S7A;S4A,Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein,translation,structural molecule activity,"ribosome, cytoplasm","RNA metabolic process, cytoplasm, nucleolus, nucleus, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,20,6.8,no,,,,, P136,43,D7,P136_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR148W,BAT2,ECA40;TWT2,"Cytosolic branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during stationary phase and repressed during logarithmic phase",cellular amino acid and derivative metabolic process,transferase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, nucleus, transferase activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,5,2.1,no,,,,, P136,44,D8,P136_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR150C,DAN1,CCW13,"Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth",transport,molecular_function,cell wall,"cell wall, molecular_function, transport",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,27,12.7,no,,,,, P136,45,D9,P136_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR153W,PGU1,PSM1;PGL1,"Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins","cellular carbohydrate metabolic process, pseudohyphal growth",hydrolase activity,extracellular region,"carbohydrate metabolic process, extracellular region, hydrolase activity, pseudohyphal growth",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,12,7,no,,,,, P136,46,D10,P136_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL005C,BYE1,,"Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit","transcription, RNA metabolic process","transcription regulator activity, protein binding",nucleus,"RNA metabolic process, nucleus, protein binding, transcription, transcription regulator activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,3,1.3,no,,,,, P136,47,D11,P136_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL030W,,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene MAE1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,10,5,no,,,,, P136,48,D12,P136_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR146C,SPE4,,"Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid","cofactor metabolic process, cellular amino acid and derivative metabolic process",transferase activity,cytoplasm,"amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, transferase activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,6,2.9,no,,,,, P136,49,E1,P136_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR286C,CTS1,,"Endochitinase, required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p",cytokinesis,hydrolase activity,"nucleus, endomembrane system, cell wall, cellular bud, extracellular region, site of polarized growth, endoplasmic reticulum, cytoplasm","carbohydrate metabolic process, cell wall, cytokinesis, endomembrane system, endoplasmic reticulum, extracellular region, hydrolase activity, nucleus",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,0,0,no,,,,, P136,50,E2,P136_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR343W,GAS2,,"1,3-beta-glucanosyltransferase, involved with Gas4p in spore wall assembly; has similarity to Gas1p","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",transferase activity,cytoplasm,"cell wall organization and biogenesis, cytoplasm, sporulation, transferase activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,10,3.1,no,,,,, P136,51,E3,P136_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML067C,ERV41,,"Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, endoplasmic reticulum, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, endoplasmic reticulum, membrane, molecular_function, transport, vesicle-mediated transport",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,4,2.2,no,,,,, P136,52,E4,P136_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML068W,ITT1,,"Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins",translation,molecular_function,cellular_component,"cellular_component, molecular_function, translation",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,8,3.4,no,,,,, P136,53,E5,P136_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML072C,TCB3,,"Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact",biological_process,lipid binding,"cellular bud, mitochondrion, cytoplasm","biological_process, cellular bud, lipid binding, mitochondrion",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,4,2.1,no,,,,, P136,54,E6,P136_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR136W,GAT2,,Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine,transcription,other,nucleus,"DNA binding, nucleus, transcription, transcription regulator activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,6,2.7,no,,,,, P136,55,E7,P136_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR172W,HOT1,,Transcription factor required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p,"response to stress, transcription, RNA metabolic process",transcription regulator activity,"nucleus, chromosome","RNA metabolic process, chromosome, nucleus, response to stress, transcription, transcription regulator activity",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,16,9.4,no,,,,, P136,56,E8,P136_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR300W,,HUF1,"Dubious open reading frame, unlikely to encode a protein; overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection, though phenotype could be due to the mutation's effects on BUD7","cytokinesis, cell cycle",molecular_function,cellular_component,"anatomical structure morphogenesis, cellular_component, cytokinesis, molecular_function, other",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,8,3.1,no,,,,, P136,57,E9,P136_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR309C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene NOP58",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,20,7.2,no,,,,, P136,58,E10,P136_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL191W,RPL35A,L35A;SOS1,"Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein","translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,3,1.6,no,,,,, P136,59,E11,P136_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL192W,ARF1,,"ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p","transport, response to stress, vesicle-mediated transport",hydrolase activity,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, hydrolase activity, transport, vesicle-mediated transport",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,182,6,3.3,no,,,,, P136,60,E12,P136_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL197C,ASF2,,Anti-silencing protein that causes derepression of silent loci when overexpressed,"transcription, RNA metabolic process",molecular_function,"nucleus, chromosome","RNA metabolic process, chromosome, molecular_function, nucleus, organelle organization and biogenesis, transcription",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,7,3.1,no,,,,, P136,61,F1,P136_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL198C,GGC1,YHM1,"Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family","transport, mitochondrion organization, cellular homeostasis",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular homeostasis, cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,10,4.2,no,,,,, P136,62,F2,P136_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL199C,,,"Putative transporter, member of the sugar porter family",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,1,0.5,no,,,,, P136,63,F3,P136_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL200C,MGT1,MGMT,DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage,"response to stress, DNA metabolic process",transferase activity,nucleus,"DNA metabolic process, nucleus, response to stress, transferase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,8,4.2,no,,,,, P136,64,F4,P136_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL201W,TRM8,,Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA,RNA metabolic process,"transferase activity, protein binding",nucleus,"RNA metabolic process, nucleus, protein binding, ribosome biogenesis, transferase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,14,4.2,no,,,,, P136,65,F5,P136_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL202W,MRPL11,YmL11,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,9,4.5,no,,,,, P136,66,F6,P136_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL203C,ACK1,,Protein that functions upstream of Pkc1p in the cell wall integrity pathway; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; non-tagged Ack1p is detected in purified mitochondria,"fungal-type cell wall organization, signaling process",molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,6,2.3,no,,,,, P136,67,F7,P136_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL204W,RTN2,,Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily,biological_process,molecular_function,"nucleus, cell cortex, endomembrane system, endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,16,5.1,no,,,,, P136,68,F8,P136_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL206W,,,Putative protein of unknown function; YDL206W is not an essential protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,14,7.6,no,,,,, P136,69,F9,P136_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL210W,UGA4,,Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane,transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,5,2.5,no,,,,, P136,70,F10,P136_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL211C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,257,1,0.4,no,,,,, P136,71,F11,P136_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL213C,NOP6,,Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes,ribosome biogenesis,RNA binding,"nucleus, nucleolus","RNA binding, RNA metabolic process, nucleolus, organelle organization and biogenesis, ribosome biogenesis",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,0,0,no,,,,, P136,72,F12,P136_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL214C,PRR2,,"Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor","conjugation, transcription, response to chemical stimulus, RNA metabolic process","transferase activity, signal transducer activity, protein kinase activity",nucleus,"RNA metabolic process, conjugation, nucleus, protein kinase activity, response to chemical stimulus, signal transducer activity, transcription, transferase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,12,3.9,no,,,,, P136,73,G1,P136_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL215C,GDH2,GDHB;GDH-B,"NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels",other,oxidoreductase activity,"mitochondrion, cytoplasm","mitochondrion, other, oxidoreductase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,6,2.1,no,,,,, P136,74,G2,P136_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL216C,RRI1,JAB1;CSN5,Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling,"conjugation, response to chemical stimulus, protein modification process","peptidase activity, hydrolase activity",nucleus,"conjugation, hydrolase activity, nucleus, peptidase activity, protein modification process, response to chemical stimulus, signal transduction",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,8,3,no,,,,, P136,75,G3,P136_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL218W,,,Putative protein of unknown function; YDL218W transcription is regulated by Azf1p and induced by starvation and aerobic conditions; expression also induced in cells treated with the mycotoxin patulin,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,3,1.4,no,,,,, P136,76,G4,P136_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL219W,DTD1,D-tyrosyl-tRNA(Tyr) deacylase,"D-Tyr-tRNA(Tyr) deacylase, functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes","translation, cellular amino acid and derivative metabolic process",hydrolase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, hydrolase activity, translation",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,18,5.8,no,,,,, P136,77,G5,P136_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL222C,FMP45,,Integral membrane protein localized to mitochondria (untagged protein); required for sporulation and maintaining sphingolipid content; has sequence similarity to SUR7 and YNL194C,"fungal-type cell wall organization, sporulation resulting in formation of a cellular spore",molecular_function,"cell cortex, membrane fraction, mitochondrion, membrane, cytoplasm","cell cortex, cell wall organization and biogenesis, membrane, mitochondrion, molecular_function, sporulation",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,152,2,1.3,no,,,,, P136,78,G6,P136_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL223C,HBT1,,"Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis","conjugation, cellular component morphogenesis, response to chemical stimulus",molecular_function,membrane fraction,"anatomical structure morphogenesis, conjugation, molecular_function, other, response to chemical stimulus",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,144,2,1.4,no,,,,, P136,79,G7,P136_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL224C,WHI4,,Putative RNA binding protein and partially redundant Whi3p homolog that regulates the cell size requirement for passage through Start and commitment to cell division,other,RNA binding,cytoplasm,"RNA binding, cytoplasm, other",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,11,6.5,no,,,,, P136,80,G8,P136_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL225W,SHS1,SEP7,"One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis","cytokinesis, cellular component morphogenesis",structural molecule activity,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, site of polarized growth, structural molecule activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,13,7,no,,,,, P136,81,G9,P136_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL226C,GCS1,,"ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p","transport, cytoskeleton organization, vesicle-mediated transport, cell cycle","enzyme regulator activity, protein binding","cytoskeleton, Golgi apparatus, cytoplasm","Golgi apparatus, cell cycle, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,4,2.2,no,,,,, P136,82,G10,P136_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL227C,HO,,"Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p",DNA metabolic process,hydrolase activity,nucleus,"DNA metabolic process, hydrolase activity, nucleus",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,5,2.9,no,,,,, P136,83,G11,P136_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL229W,SSB1,YG101,"Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in folding of newly-made polypeptide chains; member of the HSP70 family; interacts with phosphatase subunit Reg1p","transport, protein folding, translation, ribosome biogenesis, RNA metabolic process","protein binding, hydrolase activity",membrane fraction,"hydrolase activity, other, protein binding, protein folding, translation",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,14,5.2,no,,,,, P136,84,G12,P136_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL230W,PTP1,,"Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria",protein modification process,"phosphoprotein phosphatase activity, hydrolase activity","mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, phosphoprotein phosphatase activity, protein modification process",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,12,6.4,no,,,,, P136,85,H1,P136_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL231C,BRE4,,"Zinc finger protein containing five transmembrane domains; null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport","transport, vesicle-mediated transport, cellular membrane organization",molecular_function,membrane,"membrane, membrane organization and biogenesis, molecular_function, transport, vesicle-mediated transport",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,10,3.1,no,,,,, P136,86,H2,P136_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL232W,OST4,,"Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex","protein modification process, cellular carbohydrate metabolic process","transferase activity, protein binding","endomembrane system, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein binding, protein modification process, transferase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,2,0.9,no,,,,, P136,87,H3,P136_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P136,88,H4,P136_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL233W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL233W is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,4,2,no,,,,, P136,89,H5,P136_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL234C,GYP7,,"GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking","vacuole organization, transport, vesicle-mediated transport, cellular membrane organization",enzyme regulator activity,cytoplasm,"cytoplasm, enzyme regulator activity, vesicle-mediated transport",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,14,6.9,no,,,,, P136,90,H6,P136_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL236W,PHO13,,Alkaline phosphatase specific for p-nitrophenyl phosphate; also has protein phosphatase activity,protein modification process,"phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, organelle organization and biogenesis, protein modification process",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,14,5.5,no,,,,, P136,91,H7,P136_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL237W,AIM6,LRC1,"Putative protein of unknown function, required for respiratory growth; YDL237W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,12,4,no,,,,, P136,92,H8,P136_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL238C,GUD1,,"Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine; activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures","heterocycle metabolic process, cellular aromatic compound metabolic process",hydrolase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, hydrolase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,12,5.5,no,,,,, P136,93,H9,P136_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL239C,ADY3,,"Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p","sporulation resulting in formation of a cellular spore, mitochondrion organization, cellular component morphogenesis, protein complex biogenesis",protein binding,"membrane, cytoskeleton","cell wall organization and biogenesis, cytoskeleton, membrane, other, protein binding, sporulation",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,13,5.8,no,,,,, P136,94,H10,P136_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL240W,LRG1,,"Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis",signaling process,enzyme regulator activity,"cellular bud, site of polarized growth, mitochondrion, cytoplasm","cell wall organization and biogenesis, cellular bud, cytoplasm, enzyme regulator activity, mitochondrion, signal transduction, site of polarized growth",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,4,1.6,no,,,,, P136,95,H11,P136_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL241W,,,Putative protein of unknown function; YDL241W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,4,1.4,no,,,,, P136,96,H12,P136_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL242W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,3,1.7,no,,,,, P137,1,A1,P137_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL243C,AAD4,,"Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response; expression induced in cells treated with the mycotoxin patulin",other,oxidoreductase activity,cellular_component,"cellular_component, other, oxidoreductase activity, response to chemical stimulus",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,26,13.7,no,,,,, P137,2,A2,P137_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR001C,NTH1,,"Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p","response to stress, cellular carbohydrate metabolic process",hydrolase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, hydrolase activity, response to stress",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,4,1.2,no,,,,, P137,3,A3,P137_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR003W,RCR2,SSH5,"Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane; similar to Rcr1p","transport, vesicle-mediated transport",molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, membrane, molecular_function, other, vacuole, vesicle-mediated transport",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,25,8.5,no,,,,, P137,4,A4,P137_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR004W,RAD57,,Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p,"response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process","protein binding, hydrolase activity",nucleus,"DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, protein binding, response to stress",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,51,24.4,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P137,5,A5,P137_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR005C,MAF1,,Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB,"transcription, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, nucleus, transcription, transcription regulator activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,46,14.6,no,,,,, P137,6,A6,P137_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR006C,SOK1,,Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13,signaling process,molecular_function,nucleus,"molecular_function, nucleus, signal transduction",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,4,1.8,no,,,,, P137,7,A7,P137_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR008C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,7,3.4,no,,,,, P137,8,A8,P137_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR009W,GAL3,,Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity,"cellular carbohydrate metabolic process, transcription, response to chemical stimulus, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, carbohydrate metabolic process, cytoplasm, response to chemical stimulus, transcription, transcription regulator activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,12,3.9,no,,,,, P137,9,A9,P137_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR010C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,37,15.2,no,,,,, P137,10,A10,P137_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR011W,SNQ2,,"Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter involved in multidrug resistance and resistance to singlet oxygen species","response to chemical stimulus, response to stress","hydrolase activity, transporter activity","membrane fraction, mitochondrion, membrane, cytoplasm, plasma membrane","hydrolase activity, membrane fraction, mitochondrion, plasma membrane, response to chemical stimulus, response to stress, transporter activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,18,8.7,no,,,,, P137,11,A11,P137_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR014W,RAD61,WPL1,"Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin","chromosome organization, cell cycle, chromosome segregation",molecular_function,"nucleus, chromosome","cell cycle, chromosome, molecular_function, nucleus, organelle organization and biogenesis",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,40,13.3,no,,,,, P137,12,A12,P137_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR015C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene HED1/YDR014W-A",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,33,18.2,no,,,,, P137,13,B1,P137_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR017C,KCS1,,"Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response and telomere maintenance",cellular carbohydrate metabolic process,transferase activity,cytoplasm,"DNA metabolic process, cytoplasm, other, response to chemical stimulus, transferase activity, transposition",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,24,11.6,no,,,,, P137,14,B2,P137_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR018C,,,"Probable membrane protein with three predicted transmembrane domains; homologous to Ybr042cp, similar to C. elegans F55A11.5 and maize 1-acyl-glycerol-3-phosphate acyltransferase",cellular lipid metabolic process,transferase activity,cellular_component,"cellular_component, lipid metabolic process, transferase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,24,7.6,no,,,,, P137,15,B3,P137_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR019C,GCV1,GSD1,"T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm",cellular amino acid and derivative metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, other, oxidoreductase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,23,11.1,no,,,,, P137,16,B4,P137_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR020C,DAS2,RRT3,Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; weak similarity with uridine kinases and with phosphoribokinases,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,24,11.9,no,,,,, P137,17,B5,P137_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR022C,CIS1,ATG31,Autophagy-specific protein required for autophagosome formation; may form a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; high-copy suppressor of CIK1 deletion,cellular membrane organization,molecular_function,cytoplasm,"cytoplasm, membrane organization and biogenesis, molecular_function, other",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,28,9.5,no,,,,, P137,18,B6,P137_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR024W,FYV1,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,28,14.5,no,,,,, P137,19,B7,P137_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR025W,RPS11A,rp41A;YS12;S18A;S11A,Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,4,1.9,no,,,,, P137,20,B8,P137_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR026C,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; Myb-like DNA-binding protein that may bind to the Ter region of rDNA; interacts physically with Fob1p",biological_process,DNA binding,"nucleus, nucleolus, ribosome, cytoplasm","DNA binding, biological_process, nucleolus, nucleus, ribosome",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,20,9.5,no,,,,, P137,21,B9,P137_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR027C,VPS54,TCS3;CGP1;LUV1,"Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p","transport, sporulation resulting in formation of a cellular spore, vesicle-mediated transport, cellular component morphogenesis",molecular_function,"mitochondrion, cytoplasmic membrane-bounded vesicle, Golgi apparatus, cytoplasm","Golgi apparatus, cell wall organization and biogenesis, cytoplasm, cytoplasmic membrane-bounded vesicle, mitochondrion, molecular_function, sporulation, transport, vesicle-mediated transport",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,21,9.3,no,,,,, P137,22,B10,P137_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR028C,REG1,SRN1;SPP43;PZF240;HEX2,"Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes","cellular carbohydrate metabolic process, transcription, generation of precursor metabolites and energy, cellular protein catabolic process, RNA metabolic process",enzyme regulator activity,cytoplasm,"RNA metabolic process, carbohydrate metabolic process, cytoplasm, enzyme regulator activity, generation of precursor metabolites and energy, protein catabolic process, transcription",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,9,4.3,no,,,,, P137,23,B11,P137_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR029W,,,"Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,28,11.6,no,,,,, P137,24,B12,P137_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR030C,RAD28,,"Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair","response to stress, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, molecular_function, nucleus, response to stress",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,20,6.7,no,,,,, P137,25,C1,P137_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR031W,MIC14,,"Mitochondrial intermembrane space protein, required for normal oxygen consumption; contains twin cysteine-x9-cysteine motifs","generation of precursor metabolites and energy, cellular respiration",molecular_function,"nucleus, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrial envelope, mitochondrion, molecular_function, nucleus",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,34,10.7,no,,,,, P137,26,C2,P137_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR032C,PST2,,"Protein with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"membrane, membrane fraction, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,14,6.6,no,,,,, P137,27,C3,P137_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR033W,MRH1,,"Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p",biological_process,molecular_function,"membrane, membrane fraction, mitochondrion, plasma membrane, cytoplasm","biological_process, membrane fraction, mitochondrion, molecular_function, plasma membrane",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,259,10,3.9,no,,,,, P137,28,C4,P137_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR034C,LYS14,,Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer,cellular amino acid and derivative metabolic process,"transcription regulator activity, DNA binding",nucleus,"amino acid and derivative metabolic process, nucleus, transcription regulator activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,6,2.7,no,,,,, P137,29,C5,P137_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR035W,ARO3,,"3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, mitochondrion, cytoplasm","amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, mitochondrion, nucleus, transferase activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,26,7.7,no,,,,, P137,30,C6,P137_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR036C,EHD3,MRP5,"3-hydroxyisobutyryl-CoA hydrolase, member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis",biological_process,hydrolase activity,"mitochondrion, cytoplasm","biological_process, hydrolase activity, mitochondrion",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,14,6,no,,,,, P137,31,C7,P137_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR042C,,,Putative protein of unknown function; expression is increased in ssu72-ts69 mutant,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,28,8.6,no,,,,, P137,32,C8,P137_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR043C,NRG1,,Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response,"cellular carbohydrate metabolic process, pseudohyphal growth, transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, carbohydrate metabolic process, nucleus, other, pseudohyphal growth, transcription, transcription regulator activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,13,6.9,no,,,,, P137,33,C9,P137_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR046C,BAP3,PAP1,"Amino acid permease involved in the uptake of cysteine, leucine, isoleucine and valine",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, plasma membrane, transport, transporter activity",,,04_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,11,5.9,no,,,,, P137,34,C10,P137_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAL064C-A,,YAL065C-A,Putative protein of unknown function; YAL064C-A is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,6,2.5,no,,,,, P137,35,C11,P137_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL091C-A,SCS22,,Protein involved in regulation of phospholipid metabolism; homolog of Scs2p; similar to D. melanogaster inturned protein,cellular lipid metabolic process,molecular_function,cellular_component,"cellular_component, lipid metabolic process, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,12,3.9,no,,,,, P137,36,C12,P137_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR269C,FMP21,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,4,2,no,,,,, P137,37,D1,P137_D1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P137,38,D2,P137_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR271W,,,Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; predicted to be involved in ribosome biogenesis,biological_process,transferase activity,cytoplasm,"cytoplasm, ribosome biogenesis, transferase activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,2,0.8,no,,,,, P137,39,D3,P137_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR273C,UBX7,CUI3,UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p,"sporulation resulting in formation of a cellular spore, cellular protein catabolic process",molecular_function,"nucleus, endomembrane system, endoplasmic reticulum, cytoplasm","endomembrane system, endoplasmic reticulum, molecular_function, nucleus, protein catabolic process, sporulation",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,3,1.3,no,,,,, P137,40,D4,P137_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR274W,CHK1,,"Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase","signaling process, protein modification process, response to stress, cell cycle, DNA metabolic process","transferase activity, protein kinase activity",nucleus,"DNA metabolic process, cell cycle, nucleus, protein kinase activity, protein modification process, response to stress, signal transduction, transferase activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,6,3,no,,,,, P137,41,D5,P137_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR277C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR278W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,4,2.1,no,,,,, P137,42,D6,P137_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR278W,DPB3,,"Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle","response to stress, transcription, DNA metabolic process, RNA metabolic process","transferase activity, DNA binding, nucleotidyltransferase activity","nucleus, chromosome","DNA metabolic process, RNA metabolic process, chromosome, nucleotidyltransferase activity, nucleus, organelle organization and biogenesis, response to stress, transcription, transferase activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,0,0,no,,,,, P137,43,D7,P137_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR279W,PAF1,,"Component of the Paf1p complex that binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cell cycle-regulated genes; homolog of human PD2/hPAF1","chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transcription regulator activity, transposition",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,0,0,no,,,,, P137,44,D8,P137_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR281C,DUG2,,Probable di- and tri-peptidase; forms a complex with Dug1p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p),"cofactor metabolic process, cellular amino acid and derivative metabolic process","peptidase activity, hydrolase activity","nucleus, cytoplasm","cofactor metabolic process, cytoplasm, hydrolase activity, nucleus, peptidase activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,5,2.4,no,,,,, P137,45,D9,P137_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR282W,MRPL27,YmL27,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,12,4.5,no,,,,, P137,46,D10,P137_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR283C,SSH1,,Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential,transport,transporter activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, transport, transporter activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,2,0.8,no,,,,, P137,47,D11,P137_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR284W,,,Putative protein of unknown function; YBR284W is not an essential gene; null mutant exhibits decreased resistance to rapamycin and wortmannin and synthetic phenotype with alpha-synuclein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,8,2.4,no,,,,, P137,48,D12,P137_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR285W,,,Putative protein of unknown function; YBR285W is not an essential gene and deletion of YBR285W leads to poor growth on glucose-minimal medium at 15C,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,6,3.1,no,,,,, P137,49,E1,P137_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR286W,APE3,APY1,"Vacuolar aminopeptidase Y, processed to mature form by Prb1p",cellular protein catabolic process,"peptidase activity, hydrolase activity","vacuole, cytoplasm","cytoplasm, hydrolase activity, peptidase activity, protein catabolic process, vacuole",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,351,0,0,no,,,,, P137,50,E2,P137_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR290W,BSD2,,"Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification","transport, cellular protein catabolic process",protein binding,"membrane, vacuole, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, protein binding, protein catabolic process, transport, vacuole",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,7,3.1,no,,,,, P137,51,E3,P137_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR291C,CTP1,,"Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,5,2.3,no,,,,, P137,52,E4,P137_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR292C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR292C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,4,1.9,no,,,,, P137,53,E5,P137_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR293W,VBA2,,Permease of basic amino acids in the vacuolar membrane,transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,0,0,no,,,,, P137,54,E6,P137_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR295W,PCA1,PAY2;CAD2,"Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function","transport, cellular homeostasis","transporter activity, hydrolase activity","membrane, plasma membrane","cellular homeostasis, hydrolase activity, other, plasma membrane, transport, transporter activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,2,0.8,no,,,,, P137,55,E7,P137_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR296C,PHO89,ITN1,"Na+/Pi cotransporter, active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,12,6.2,no,,,,, P137,56,E8,P137_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR297W,MAL33,MALR;MAL3R,"MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C","cellular carbohydrate metabolic process, transcription, RNA metabolic process",other,nucleus,"DNA binding, RNA metabolic process, carbohydrate metabolic process, nucleus, transcription, transcription regulator activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,6,2,no,,,,, P137,57,E9,P137_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR298C,MAL31,MALT;MAL3T,"Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL3 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; functional in genomic reference strain S288C",transport,transporter activity,membrane fraction,"membrane fraction, transport, transporter activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,259,1,0.4,no,,,,, P137,58,E10,P137_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR300C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR301W; YBR300C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,1,0.5,no,,,,, P137,59,E11,P137_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL001W-A,,,Putative protein of unknown function; YCL001W-A gene has similarity to DOM34 and is present in a region duplicated between chromosomes XIV and III,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,3,1.7,no,,,,, P137,60,E12,P137_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR020W-B,HTL1,,"Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance","response to stress, chromosome organization, transcription, cell cycle, RNA metabolic process",other,nucleus,"RNA metabolic process, cell cycle, nucleus, organelle organization and biogenesis, other, response to stress, transcription",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,6,2.3,no,,,,, P137,61,F1,P137_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR024C,SLM5,,Mitochondrial asparaginyl-tRNA synthetase,"mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","ligase activity, mitochondrion, translation",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,8,3,no,,,,, P137,62,F2,P137_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR024C-A,PMP1,,"Small single-membrane span proteolipid that functions as a regulatory subunit of the plasma membrane H(+)-ATPase Pma1p, forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines",transport,enzyme regulator activity,"membrane, plasma membrane","enzyme regulator activity, membrane, plasma membrane, transport",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,2,0.7,no,,,,, P137,63,F3,P137_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR025C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YCR025C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,2,1.1,no,,,,, P137,64,F4,P137_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR026C,NPP1,,Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation,response to stress,hydrolase activity,cellular_component,"cellular_component, hydrolase activity, other, response to stress",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,6,1.9,no,,,,, P137,65,F5,P137_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR027C,RHB1,RSG1,Putative Rheb-related GTPase involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins,"transport, vesicle-mediated transport",hydrolase activity,"membrane, plasma membrane","hydrolase activity, membrane, plasma membrane, transport, vesicle-mediated transport",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,6,2,no,,,,, P137,66,F6,P137_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR028C,FEN2,,Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph,"transport, vesicle-mediated transport, cellular membrane organization",transporter activity,"membrane, plasma membrane","membrane organization and biogenesis, plasma membrane, transport, transporter activity, vesicle-mediated transport",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,18,6.9,no,,,,, P137,67,F7,P137_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR031C,RPS14A,rp59A;S14A;RPL59;CRY1,"Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins","translation, ribosome biogenesis, RNA metabolic process","RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, nucleolus, nucleus, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,6,1.9,no,,,,, P137,68,F8,P137_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR034W,FEN1,VBM2;GNS1;ELO2,"Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway","transport, vesicle-mediated transport, cellular lipid metabolic process",transferase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, transferase activity, vesicle-mediated transport",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,7,3.3,no,,,,, P137,69,F9,P137_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR036W,RBK1,,Putative ribokinase,"cellular carbohydrate metabolic process, heterocycle metabolic process",transferase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, nucleus, other, transferase activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,9,4.9,no,,,,, P137,70,F10,P137_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR037C,PHO87,,"Low-affinity inorganic phosphate (Pi) transporter, involved in activation of PHO pathway; expression is independent of Pi concentration and Pho4p activity; contains 12 membrane-spanning segments",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,2,0.8,no,,,,, P137,71,F11,P137_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR043C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi apparatus; YCR043C is not an essential gene,biological_process,molecular_function,"site of polarized growth, cytoplasm, Golgi apparatus","Golgi apparatus, biological_process, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,1,0.4,no,,,,, P137,72,F12,P137_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR044C,PER1,COS16,"Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1","protein modification process, cellular lipid metabolic process, cellular homeostasis",molecular_function,"vacuole, membrane, endoplasmic reticulum, cytoplasm","cellular homeostasis, cytoplasm, endoplasmic reticulum, lipid metabolic process, membrane, molecular_function, protein modification process, vacuole",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,6,2.7,no,,,,, P137,73,G1,P137_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR045C,RRT12,OSW3,Probable subtilisin-family protease with a role in formation of the dityrosine layer of spore walls; localizes to the spore wall and also the nuclear envelope and ER region in mature spores,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis","peptidase activity, hydrolase activity","cell wall, nucleus, endomembrane system","biological_process, cellular_component, hydrolase activity, peptidase activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,2,1.1,no,,,,, P137,74,G2,P137_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR049C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,3,1.5,no,,,,, P137,75,G3,P137_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR050C,,,Non-essential protein of unknown function; deletion mutant is synthetically sick or lethal with alpha-synuclein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,7,3.6,no,,,,, P137,76,G4,P137_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR051W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,9,4.7,no,,,,, P137,77,G5,P137_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR059C,YIH1,,"Protein that inhibits activation of Gcn2p, an eIF2 alpha subunit protein kinase, by competing for Gcn1p binding, thus impacting gene expression in response to starvation; has sequence and functional similarity to the mouse IMPACT gene",cellular amino acid and derivative metabolic process,molecular_function,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, molecular_function, nucleus",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,0,0,no,,,,, P137,78,G6,P137_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR061W,,YCR062W,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; induced by treatment with 8-methoxypsoralen and UVA irradiation,other,molecular_function,cytoplasm,"cytoplasm, molecular_function, other",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,10,3.1,no,,,,, P137,79,G7,P137_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR063W,BUD31,CWC14,Component of the SF3b subcomplex of the U2 snRNP; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern,"cytokinesis, cell cycle, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, anatomical structure morphogenesis, cytokinesis, molecular_function, nucleus",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,1,0.6,no,,,,, P137,80,G8,P137_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR065W,HCM1,,"Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role","cytoskeleton organization, transcription, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, chromosome","DNA binding, RNA metabolic process, cell cycle, cytoskeleton organization and biogenesis, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,146,10,6.8,no,,,,, P137,81,G9,P137_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR066W,RAD18,,"E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair","response to stress, DNA metabolic process, protein modification process","DNA binding, ligase activity, hydrolase activity","nucleus, chromosome","DNA binding, DNA metabolic process, chromosome, hydrolase activity, ligase activity, nucleus, response to stress",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,2,0.9,no,,,,, P137,82,G10,P137_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR068W,ATG15,CVT17;AUT5,Lipase required for intravacuolar lysis of autophagic bodies and Cvt bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway,cellular membrane organization,hydrolase activity,"membrane, vacuole, cytoplasm","cytoplasm, hydrolase activity, membrane, membrane organization and biogenesis, other, protein modification process, vacuole",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,4,1.2,no,,,,, P137,83,G11,P137_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR071C,IMG2,,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,2,1.1,no,,,,, P137,84,G12,P137_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR073W-A,SOL2,YCRX13W,"Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol1p, Sol3p, and Sol4p",transport,"molecular_function, hydrolase activity",cytoplasm,"cytoplasm, molecular_function, transport",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,4,1.8,no,,,,, P137,85,H1,P137_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR076C,,,Putative protein of unknown function; YCR076C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,3,1.7,no,,,,, P137,86,H2,P137_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR077C,PAT1,MRT1,"Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p","translation, chromosome segregation, RNA metabolic process",molecular_function,"ribosome, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, other, ribosome, translation",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,1,0.6,no,,,,, P137,87,H3,P137_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P137,88,H4,P137_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR079W,PTC6,PPP2;AUP1,Mitochondrial protein phosphatase of type 2C with similarity to mammalian PP1Ks; involved in mitophagy; null mutant is sensitive to rapamycin and has decreased phosphorylation of the Pda1 subunit of pyruvate dehydrogenase,"response to stress, protein modification process","phosphoprotein phosphatase activity, hydrolase activity","mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrial envelope, mitochondrion, other, phosphoprotein phosphatase activity, protein modification process, response to stress",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,6,2,no,,,,, P137,89,H5,P137_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR081W,SRB8,MED12;YCR080W;SSN5;NUT6;GIG1,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,4,1.2,no,,,,, P137,90,H6,P137_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR082W,AHC2,,"Protein of unknown function, putative transcriptional regulator; proposed to be a Ada Histone acetyltransferase complex component; GFP tagged protein is localized to the cytoplasm and nucleus",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,0,0,no,,,,, P137,91,H7,P137_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR085W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,7,3.3,no,,,,, P137,92,H8,P137_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR086W,CSM1,,Nucleolar protein that forms a complex with Lrs4p and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation,"chromosome segregation, meiosis, chromosome organization, cell cycle",molecular_function,"nucleus, endomembrane system, chromosome, nucleolus","DNA metabolic process, cell cycle, chromosome, endomembrane system, meiosis, molecular_function, nucleolus, nucleus, response to chemical stimulus",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,8,2.7,no,,,,, P137,93,H9,P137_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR087C-A,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene,biological_process,molecular_function,"nucleus, nucleolus","biological_process, molecular_function, nucleolus",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,6,2.3,no,,,,, P137,94,H10,P137_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR087W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized gene YCR087C-A; YCR087W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,2,1.1,no,,,,, P137,95,H11,P137_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL003W,COX16,,"Mitochondrial inner membrane protein, required for assembly of cytochrome c oxidase","mitochondrion organization, protein complex biogenesis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, molecular_function, other",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,39,21.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P137,96,H12,P137_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL004C,SYS1,,Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation,"transport, vesicle-mediated transport, vesicle organization",molecular_function,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, membrane, molecular_function, organelle organization and biogenesis, transport, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,12,5.1,no,,,,, P138,1,A1,P138_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL006C,CTK2,,"Beta subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity","translation, transcription, protein modification process, RNA metabolic process","transferase activity, protein kinase activity","nucleus, nucleolus","RNA metabolic process, nucleus, protein kinase activity, protein modification process, transcription, transferase activity, translation",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,326,10,3.1,no,,,,, P138,2,A2,P138_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL007C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,338,14,4.1,no,,,,, P138,3,A3,P138_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL012C,VTC4,YJL012C-A;PHM3,Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion,"vacuole organization, transport, cellular membrane organization",transferase activity,"vacuole, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vacuole",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,184,1,0.5,no,,,,, P138,4,A4,P138_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL013C,MAD3,,"Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover","meiosis, signaling process, cell cycle, chromosome segregation",molecular_function,nucleus,"cell cycle, molecular_function, nucleus",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,277,78,28.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P138,5,A5,P138_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL016W,,YJL017W,Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; conserved in closely related Saccharomyces species,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,338,24,7.1,no,,,,, P138,6,A6,P138_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL016W,,YJL017W,Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; conserved in closely related Saccharomyces species,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,302,2,0.7,no,,,,, P138,7,A7,P138_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL020C,BBC1,YJL021C;MTI1,Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches,cytoskeleton organization,protein binding,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,160,12,7.5,no,,,,, P138,8,A8,P138_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL020C,BBC1,YJL021C;MTI1,Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches,cytoskeleton organization,protein binding,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,198,12,6.1,no,,,,, P138,9,A9,P138_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL022W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PET130",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,274,6,2.2,no,,,,, P138,10,A10,P138_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL023C,PET130,,"Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,322,20,6.2,no,,,,, P138,11,A11,P138_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL024C,APS3,YKS7,"Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasm","cytoplasm, membrane, molecular_function, transport, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,2,1,no,,,,, P138,12,A12,P138_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL027C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,224,5,2.2,no,,,,, P138,13,B1,P138_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL028W,,,"Protein of unknown function; may interact with ribosomes, based on co-purification experiments",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,204,10,4.9,no,,,,, P138,14,B2,P138_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL029C,VPS53,,"Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting","transport, vesicle-mediated transport",protein binding,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, protein binding, transport, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,211,17,8.1,no,,,,, P138,15,B3,P138_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR001W,AVT1,,"Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters",transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,208,26,12.5,no,,,,, P138,16,B4,P138_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR004C,SAG1,AG(ALPHA)1,"Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor","conjugation, response to chemical stimulus",protein binding,cell wall,"cell wall, conjugation, protein binding, response to chemical stimulus",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,304,6,2,no,,,,, P138,17,B5,P138_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR005W,APL1,YAP80,"Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, plasma membrane, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, plasma membrane, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,164,12,7.3,no,,,,, P138,18,B6,P138_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR008W,,,Putative protein of unknown function; expression repressed by inosine and choline in an Opi1p-dependent manner; expression induced by mild heat-stress on a non-fermentable carbon source.,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,214,9,4.2,no,,,,, P138,19,B7,P138_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR009C,TDH2,GAPDH;GLD2,"Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,"cell wall, membrane fraction, mitochondrion, cytoplasm","carbohydrate metabolic process, cell wall, cytoplasm, generation of precursor metabolites and energy, mitochondrion, other, oxidoreductase activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,184,12,6.5,no,,,,, P138,20,B8,P138_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR010C-A,SPC1,,"Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex",transport,molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, protein modification process, transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,338,20,5.9,no,,,,, P138,21,B9,P138_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR010W,MET3,,"ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism",cellular amino acid and derivative metabolic process,"transferase activity, nucleotidyltransferase activity","mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, nucleotidyltransferase activity, other, transferase activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,178,13,7.3,no,,,,, P138,22,B10,P138_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR011C,,,Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,3,1.6,no,,,,, P138,23,B11,P138_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR014W,TMA22,RBF22,"Protein of unknown function; associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; similar to human GRAP and human DRP1, which interacts with human Tma20p homolog MCT-1",biological_process,RNA binding,"ribosome, cytoplasm","RNA binding, biological_process, cytoplasm, ribosome",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,264,6,2.3,no,,,,, P138,24,B12,P138_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR015W,,,Putative protein of unknown function; localizes to the endoplasmic reticulum and cytoplasm; predicted to encode a membrane transporter based on phylogenetic analysis; YJR015W is a non-essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endoplasmic reticulum, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,327,0,0,no,,,,, P138,25,C1,P138_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR018W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,170,10,5.9,no,,,,, P138,26,C2,P138_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR019C,TES1,PTE1,Peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids,cellular lipid metabolic process,hydrolase activity,"peroxisome, mitochondrion, cytoplasm","hydrolase activity, lipid metabolic process, mitochondrion, peroxisome",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,188,2,1.1,no,,,,, P138,27,C3,P138_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR020W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,177,4,2.3,no,,,,, P138,28,C4,P138_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR021C,REC107,MER2,Protein involved in early stages of meiotic recombination; involved in coordination between the initiation of recombination and the first division of meiosis; part of a complex (Rec107p-Mei4p-Rec114p) required for ds break formation,"meiosis, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleus",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,6,3.3,no,,,,, P138,29,C5,P138_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR024C,MDE1,,5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant,cellular amino acid and derivative metabolic process,lyase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,2,1,no,,,,, P138,30,C6,P138_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR025C,BNA1,HAD1,"3-hydroxyanthranilic acid dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p","cofactor metabolic process, vitamin metabolic process",oxidoreductase activity,cytoplasm,"cofactor metabolic process, cytoplasm, oxidoreductase activity, vitamin metabolic process",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,3,1.5,no,,,,, P138,31,C7,P138_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR026W,,,,,,,,,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,5,2.5,no,,,,, P138,32,C8,P138_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR030C,,,Putative protein of unknown function; expression repressed in carbon limited vs carbon replete chemostat cultures; YJR030C is a non-essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,3,1.7,no,,,,, P138,33,C9,P138_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR031C,GEA1,,"Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea2p","transport, cytoskeleton organization, response to stress, vesicle-mediated transport",enzyme regulator activity,"cytoplasmic membrane-bounded vesicle, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton organization and biogenesis, enzyme regulator activity, membrane, organelle organization and biogenesis, transport, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,260,14,5.4,no,,,,, P138,34,C10,P138_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR032W,CPR7,,"Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity","response to stress, protein folding","isomerase activity, protein binding",cytoplasm,"cytoplasm, isomerase activity, protein binding, response to stress",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,174,2,1.1,no,,,,, P138,35,C11,P138_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR033C,RAV1,SOI3,"Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate","transport, vesicle-mediated transport, cellular homeostasis, protein complex biogenesis",molecular_function,"membrane, cytoplasm","cellular homeostasis, cytoplasm, membrane, molecular_function, other, transport, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,8,2.8,no,,,,, P138,36,C12,P138_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR035W,RAD26,,Protein involved in transcription-coupled nucleotide excision repair of UV-induced DNA lesions; recruitment to DNA lesions is dependent on an elongating RNA polymerase II; homolog of human CSB protein,"response to stress, DNA metabolic process",hydrolase activity,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, hydrolase activity, nucleus, response to stress",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,28,9,no,,,,, P138,37,D1,P138_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR036C,HUL4,,"Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability",protein modification process,ligase activity,cellular_component,"cellular_component, ligase activity, protein modification process",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,6,3,no,,,,, P138,38,D2,P138_D2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P138,39,D3,P138_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR037W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene HUL4/YJR036C; deletion mutant has decreased spore survival in Drosophila feces",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,2,1,no,,,,, P138,40,D4,P138_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR038C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,10,4.3,no,,,,, P138,41,D5,P138_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR040W,GEF1,CLC,"Voltage-gated chloride channel localized to the golgi, the endosomal system, and plasma membrane, and involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels",cellular homeostasis,transporter activity,"vacuole, membrane, endoplasmic reticulum, Golgi apparatus, cytoplasm, plasma membrane","Golgi apparatus, cellular homeostasis, cytoplasm, transporter activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,10,5.9,no,,,,, P138,42,D6,P138_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR043C,POL32,,"Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p","response to stress, DNA metabolic process, RNA metabolic process","transferase activity, nucleotidyltransferase activity, hydrolase activity","nucleus, chromosome","DNA metabolic process, RNA metabolic process, chromosome, hydrolase activity, nucleotidyltransferase activity, nucleus, response to stress, transferase activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,256,28,10.9,no,,,,, P138,43,D7,P138_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR047C,ANB1,eIF-5A;TIF51B;HYP1,"Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions",translation,RNA binding,"ribosome, cytoplasm","ribosome, translation, translation regulator activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,28,12.1,no,,,,, P138,44,D8,P138_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR048W,CYC1,iso-1-cytochrome c,"Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration","generation of precursor metabolites and energy, cellular respiration",other,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, generation of precursor metabolites and energy, mitochondrial envelope, mitochondrion, other",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,28,10.9,no,,,,, P138,45,D9,P138_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR049C,UTR1,,ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p),"cofactor metabolic process, vitamin metabolic process, cellular homeostasis",transferase activity,"nucleus, cytoplasm","cellular homeostasis, cofactor metabolic process, cytoplasm, nucleus, transferase activity, vitamin metabolic process",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,25,12.5,no,,,,, P138,46,D10,P138_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR050W,ISY1,NTC30;UTR3,"Member of NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of spliceosome containing U2, U5, and U6 snRNAs, interacts with Prp16p to modulate splicing fidelity; isy1 syf2 cells have defective spindles",RNA metabolic process,other,nucleus,"RNA metabolic process, nucleus, other",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,6,3.3,no,,,,, P138,47,D11,P138_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR051W,OSM1,FRDS2,"Fumarate reductase, catalyzes the reduction of fumarate to succinate, required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity","response to stress, response to chemical stimulus",oxidoreductase activity,"mitochondrion, cytoplasm","mitochondrion, other, oxidoreductase activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,8,3.9,no,,,,, P138,48,D12,P138_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR052W,RAD7,,Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex,"protein modification process, response to stress, chromosome organization, DNA metabolic process, cellular protein catabolic process","ligase activity, hydrolase activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, hydrolase activity, ligase activity, nucleus, organelle organization and biogenesis, other, protein catabolic process, protein modification process, response to stress",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,10,4.1,no,,,,, P138,49,E1,P138_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR053W,BFA1,IBD1,Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis,"signaling process, cell cycle",enzyme regulator activity,"cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoplasm, cytoskeleton, enzyme regulator activity, microtubule organizing center",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,282,18,6.4,no,,,,, P138,50,E2,P138_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR054W,,,Vacuolar protein of unknown function; potential Cdc28p substrate,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,22,10.4,no,,,,, P138,51,E3,P138_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR055W,HIT1,,"Protein of unknown function, required for growth at high temperature",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,6,2.1,no,,,,, P138,52,E4,P138_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR056C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,7,4.1,no,,,,, P138,53,E5,P138_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR058C,APS2,YAP17,"Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, plasma membrane, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, plasma membrane, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,4,1.3,no,,,,, P138,54,E6,P138_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR059W,PTK2,STK2,Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake,"transport, cell cycle, cellular homeostasis","transferase activity, protein kinase activity","nucleus, membrane, plasma membrane, cytoplasm","cell cycle, cellular homeostasis, cytoplasm, nucleus, other, plasma membrane, protein kinase activity, transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,9,3.9,no,,,,, P138,55,E7,P138_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR060W,CBF1,CPF1;CEP1,"Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA","transcription, cellular amino acid and derivative metabolic process, chromosome segregation, chromosome organization, RNA metabolic process",DNA binding,"nucleus, chromosome, mitochondrion, cytoplasm","DNA binding, RNA metabolic process, amino acid and derivative metabolic process, chromosome, mitochondrion, nucleus, organelle organization and biogenesis, other, response to chemical stimulus, transcription, transcription regulator activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,183,25,13.7,no,,,,, P138,56,E8,P138_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR061W,,,"Putative protein of unknown function; non-essential gene with similarity to Mnn4, a putative membrane protein involved in glycosylation; transcription repressed by Rm101p",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,9,4,no,,,,, P138,57,E9,P138_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR062C,NTA1,DEA1,"Amidase, removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation",protein modification process,hydrolase activity,"mitochondrion, cytoplasm","hydrolase activity, mitochondrion, protein catabolic process, protein modification process",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,20,9.9,no,,,,, P138,58,E10,P138_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR063W,RPA12,A12.2;RRN4,"RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex","transcription, RNA metabolic process",molecular_function,"nucleus, nucleolus","RNA metabolic process, hydrolase activity, nucleolus, nucleotidyltransferase activity, nucleus, ribosome biogenesis, transcription, transferase activity",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,173,3,1.7,no,,,,, P138,59,E11,P138_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL096C,OPI6,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene PMT1/YDL095W; YDL096C is not essential",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,192,12,6.3,no,,,,, P138,60,E12,P138_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL099W,BUG1,,"Cis-golgi localized protein involved in ER to Golgi transport; forms a complex with the mammalian GRASP65 homolog, Grh1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes","transport, vesicle-mediated transport",molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, molecular_function, transport, vesicle-mediated transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,288,12,4.2,no,,,,, P138,61,F1,P138_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL100C,GET3,ARR4,"Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; subunit of the GET complex, which is involved in Golgi to ER trafficking and insertion of proteins into the ER membrane; has low-level ATPase activity","transport, signaling process, response to chemical stimulus, response to stress, vesicle-mediated transport, conjugation, cellular membrane organization","hydrolase activity, enzyme regulator activity","endoplasmic reticulum, cytoplasm","conjugation, cytoplasm, endoplasmic reticulum, enzyme regulator activity, hydrolase activity, response to chemical stimulus, response to stress, signal transduction, transport, vesicle-mediated transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,140,6,4.3,no,,,,, P138,62,F2,P138_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL101C,DUN1,,"Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair","signaling process, protein modification process, response to stress, cell cycle, DNA metabolic process","transferase activity, protein kinase activity",nucleus,"DNA metabolic process, cell cycle, nucleus, protein kinase activity, protein modification process, response to stress, signal transduction",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,9,3.8,no,,,,, P138,63,F3,P138_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL104C,QRI7,,"Highly conserved mitochondrial protein, essential for stability of the mitochondrial genome; functional homolog of the essential E. coli ygjD gene; member of a family of proteins putatively involved in genome maintenance",mitochondrion organization,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,2,1.1,no,,,,, P138,64,F4,P138_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL106C,PHO2,phoB;GRF10;BAS2,Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p,"transcription, cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process, chromosome organization, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, amino acid and derivative metabolic process, aromatic compound metabolic process, heterocycle metabolic process, nucleus, response to stress, transcription, transcription regulator activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,10,3.8,no,,,,, P138,65,F5,P138_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL107W,MSS2,,"Peripherally bound inner membrane protein of the mitochondrial matrix involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p","mitochondrion organization, cellular membrane organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,244,10,4.1,no,,,,, P138,66,F6,P138_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL109C,,,Putative lipase; involved in lipid metabolism; YDL109C is not an essential gene,cellular lipid metabolic process,molecular_function,cellular_component,"cellular_component, lipid metabolic process, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,8,2.8,no,,,,, P138,67,F7,P138_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL110C,TMA17,,Protein of unknown function that associates with ribosomes; heterozygous deletion demonstrated increases in chromosome instability in a rad9 deletion background; protein abundance is decreased upon intracellular iron depletion,biological_process,molecular_function,"nucleus, ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus, ribosome",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,2,1.2,no,,,,, P138,68,F8,P138_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL112W,TRM3,,"2'-O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs",RNA metabolic process,transferase activity,cytoplasm,"RNA metabolic process, cytoplasm, transferase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,8,4.3,no,,,,, P138,69,F9,P138_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL113C,ATG20,CVT20;SNX42,Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate,"transport, response to stress, vesicle-mediated transport",lipid binding,"membrane fraction, cytoplasm","cytoplasm, lipid binding, membrane fraction, response to stress, transport, vesicle-mediated transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,16,7.6,no,,,,, P138,70,F10,P138_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL114W,,,Putative protein of unknown function with similarity to acyl-carrier-protein reductases; YDL114W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,6,3.4,no,,,,, P138,71,F11,P138_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL115C,IWR1,,Protein involved in transcription from polymerase II promoters; interacts with with most of the polymerase II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to the K1 killer toxin,"chromosome organization, transcription, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, meiosis, molecular_function, nucleus, transcription",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,347,38,11,no,,,,, P138,72,F12,P138_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL116W,NUP84,,"Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis","transport, response to stress, ribosome biogenesis, cellular membrane organization, nucleus organization",structural molecule activity,"nucleus, endomembrane system, membrane","endomembrane system, membrane, membrane organization and biogenesis, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, other, response to stress, structural molecule activity, transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,204,10,4.9,no,,,,, P138,73,G1,P138_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL117W,CYK3,,SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype and genetic interactions suggest a role in cytokinesis,cytokinesis,molecular_function,"cellular bud, site of polarized growth, cytoplasm","cellular bud, cytokinesis, cytoplasm, molecular_function, site of polarized growth",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,8,2.8,no,,,,, P138,74,G2,P138_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL118W,,,"Non-essential protein of unconfirmed function; mutants are defective in telomere maintenance, and are synthetically sick or lethal with alpha-synuclein",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,324,20,6.2,no,,,,, P138,75,G3,P138_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL119C,,,"Putative mitochondrial transport protein; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in purified mitochondria",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,22,8.6,no,,,,, P138,76,G4,P138_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL121C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic retiuculum; YDL121C is not an essential protein,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,4,1.3,no,,,,, P138,77,G5,P138_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL122W,UBP1,,Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains,protein modification process,"peptidase activity, hydrolase activity","endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, hydrolase activity, peptidase activity, protein modification process",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,1,0.4,no,,,,, P138,78,G6,P138_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL123W,SNA4,,"Protein of unknown function, localized to the vacuolar outer membrane; predicted to be palmitoylated",biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,6,3.1,no,,,,, P138,79,G7,P138_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL124W,,,"NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family","response to stress, response to chemical stimulus, cellular aromatic compound metabolic process",oxidoreductase activity,"nucleus, membrane fraction, cytoplasm","aromatic compound metabolic process, cytoplasm, nucleus, other, oxidoreductase activity, response to chemical stimulus, response to stress",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,2,0.7,no,,,,, P138,80,G8,P138_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL125C,HNT1,,"Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint",other,hydrolase activity,"nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, other",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,8,4.5,no,,,,, P138,81,G9,P138_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL127W,PCL2,CLN4,"Cyclin, interacts with cyclin-dependent kinase Pho85p; member of the Pcl1,2-like subfamily, involved in the regulation of polarized growth and morphogenesis and progression through the cell cycle; localizes to sites of polarized cell growth","cytoskeleton organization, cell cycle",enzyme regulator activity,"cellular bud, nucleus, site of polarized growth","anatomical structure morphogenesis, cell cycle, cellular bud, enzyme regulator activity, nucleus, other, site of polarized growth",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,2,1,no,,,,, P138,82,G10,P138_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL128W,VCX1,MNR1;HUM1,"Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter","transport, cellular homeostasis",transporter activity,"vacuole, cytoplasm","cellular homeostasis, cytoplasm, transport, transporter activity, vacuole",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,4,2.1,no,,,,, P138,83,G11,P138_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL129W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YDL129W is not an essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,244,4,1.6,no,,,,, P138,84,G12,P138_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL130W,RPP1B,YP1beta;P1B;L44;Ax;RPLA3;RPL44,"Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; accumulation is regulated by phosphorylation and interaction with the P2 stalk component",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,4,1.9,no,,,,, P138,85,H1,P138_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL131W,LYS21,,"Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p",cellular amino acid and derivative metabolic process,transferase activity,nucleus,"amino acid and derivative metabolic process, nucleus, transferase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,2,0.8,no,,,,, P138,86,H2,P138_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL133W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,219,6,2.7,no,,,,, P138,87,H3,P138_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P138,88,H4,P138_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL134C,PPH21,PPH1,"Catalytic subunit of protein phosphatase 2A (PP2A), functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis","cell budding, signaling process, cytoskeleton organization, translation, protein modification process, cell cycle","hydrolase activity, phosphoprotein phosphatase activity",other,"cell budding, cell cycle, cytoskeleton organization and biogenesis, hydrolase activity, organelle organization and biogenesis, other, phosphoprotein phosphatase activity, protein modification process, translation",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,6,3,no,,,,, P138,89,H5,P138_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL133C-A,RPL41B,YL41;L47B;L41B;YDL134C-A;RPL47B,"Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Ap and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,12,4.3,no,,,,, P138,90,H6,P138_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL135C,RDI1,,Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p,"vacuole organization, signaling process, cytoskeleton organization, cellular membrane organization",enzyme regulator activity,"membrane fraction, cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoplasm, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, signal transduction, site of polarized growth",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,5,2.5,no,,,,, P138,91,H7,P138_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL136W,RPL35B,L35B;SOS2,"Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein","translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,5,2.6,no,,,,, P138,92,H8,P138_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL137W,ARF2,,"ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p","transport, response to stress, vesicle-mediated transport",hydrolase activity,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, hydrolase activity, transport, vesicle-mediated transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,28,8.9,no,,,,, P138,93,H9,P138_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL138W,RGT2,,Plasma membrane high glucose sensor that regulates glucose transport; contains 12 predicted transmembrane segments and a long C-terminal tail required for induction of hexose transporters; highly similar to Snf3p,"signaling process, response to chemical stimulus",signal transducer activity,"membrane, plasma membrane","other, plasma membrane, response to chemical stimulus, signal transducer activity, signal transduction",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,14,8.2,no,,,,, P138,94,H10,P138_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL142C,CRD1,CLS1,"Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis","mitochondrion organization, cellular homeostasis, cellular membrane organization",transferase activity,"mitochondrial envelope, mitochondrion, cytoplasm","membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, transferase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,0,0,no,,,,, P138,95,H11,P138_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL144C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL144C is not an essential gene.,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,8,3.7,no,,,,, P138,96,H12,P138_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL146W,LDB17,,"Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck","transport, vesicle-mediated transport, cellular membrane organization",molecular_function,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","biological_process, cellular bud, cytoplasm, molecular_function, site of polarized growth",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,3,1.3,no,,,,, P139,1,A1,P139_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL149W,ATG9,APG9;CVT7;AUT9,"Transmembrane protein involved in forming Cvt and autophagic vesicles; cycles between the phagophore assembly site (PAS) and other cytosolic punctate structures, not found in autophagosomes; may be involved in membrane delivery to the PAS","vacuole organization, transport, protein complex biogenesis, response to stress, cellular membrane organization",molecular_function,"membrane fraction, mitochondrion, membrane, cytoplasm","cytoplasm, membrane, membrane fraction, membrane organization and biogenesis, mitochondrion, molecular_function, organelle organization and biogenesis, response to stress, transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,302,6,2,no,,,,, P139,2,A2,P139_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL151C,BUD30,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 96% of ORF overlaps the verified gene RPC53; diploid mutant displays a weak budding pattern phenotype in a systematic assay","sporulation resulting in formation of a cellular spore, cytokinesis, transcription, cell cycle, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, anatomical structure morphogenesis, cellular_component, cytokinesis, molecular_function, sporulation, transcription",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,257,6,2.3,no,,,,, P139,3,A3,P139_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL154W,MSH5,,"Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans","meiosis, cell cycle, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, cell cycle, meiosis, molecular_function, nucleus",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,0,0,no,,,,, P139,4,A4,P139_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL155W,CLB3,,"B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation","cytoskeleton organization, cell cycle",enzyme regulator activity,"nucleus, cytoplasm","cell cycle, cytoplasm, enzyme regulator activity, nucleus",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,2,1.1,no,,,,, P139,5,A5,P139_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL156W,,,Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,10,3,no,,,,, P139,6,A6,P139_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL157C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,16,7.3,no,,,,, P139,7,A7,P139_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL158C,,,"Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,6,2.5,no,,,,, P139,8,A8,P139_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL159W,STE7,,"Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, and in the pseudohyphal/invasive growth pathway, through phosphorylation of Kss1p; phosphorylated by Ste11p, degraded by ubiquitin pathway","signaling process, transposition, response to chemical stimulus, protein modification process, conjugation, pseudohyphal growth","transferase activity, protein kinase activity","site of polarized growth, cytoplasm","conjugation, cytoplasm, other, protein kinase activity, protein modification process, pseudohyphal growth, response to chemical stimulus, signal transduction, site of polarized growth, transferase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P139,9,A9,P139_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL160C,DHH1,,"Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation","response to chemical stimulus, conjugation, cellular component morphogenesis, RNA metabolic process","hydrolase activity, helicase activity, protein binding",cytoplasm,"RNA metabolic process, anatomical structure morphogenesis, conjugation, cytoplasm, helicase activity, other, protein binding, response to chemical stimulus",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,286,20,7,no,,,,, P139,10,A10,P139_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL161W,ENT1,,Epsin-like protein involved in endocytosis and actin patch assembly and functionally redundant with Ent2p; binds clathrin via a clathrin-binding domain motif at C-terminus,"transport, cytoskeleton organization, vesicle-mediated transport, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, site of polarized growth, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,1,0.4,no,,,,, P139,11,A11,P139_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL162C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps ENT1/YDL161W, a verified gene involved in endocytosis and actin cortical patch assembly",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,2,0.6,no,,,,, P139,12,A12,P139_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL167C,NRP1,,Putative RNA binding protein of unknown function; localizes to stress granules induced by glucose deprivation; predicted to be involved in ribosome biogenesis,biological_process,molecular_function,cytoplasm,"cytoplasm, molecular_function, ribosome biogenesis",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,0,0,no,,,,, P139,13,B1,P139_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL168W,SFA1,ADH5,"Bifunctional enzyme containing both alcohol dehydrogenase and glutathione-dependent formaldehyde dehydrogenase activities, functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p","cellular amino acid and derivative metabolic process, heterocycle metabolic process",oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, heterocycle metabolic process, mitochondrion, other, oxidoreductase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,0,0,no,,,,, P139,14,B2,P139_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL169C,UGX2,,"Protein of unknown function, transcript accumulates in response to any combination of stress conditions",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,2,0.7,no,,,,, P139,15,B3,P139_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL170W,UGA3,,"Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus","transcription, cellular amino acid and derivative metabolic process, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, amino acid and derivative metabolic process, aromatic compound metabolic process, lipid metabolic process, nucleus, other, transcription, transcription regulator activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,2,0.9,no,,,,, P139,16,B4,P139_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL171C,GLT1,,"NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source",cellular amino acid and derivative metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, other, oxidoreductase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,8,3.7,no,,,,, P139,17,B5,P139_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL172C,,,"Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,6,2,no,,,,, P139,18,B6,P139_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL173W,PAR32,,Putative protein of unknown function; hyperphosphorylated upon rapamycin treatment in a Tap42p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; PAR32 is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,162,6,3.7,no,,,,, P139,19,B7,P139_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL174C,DLD1,,"D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane","generation of precursor metabolites and energy, cellular respiration, cellular carbohydrate metabolic process",oxidoreductase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","carbohydrate metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,11,4.8,no,,,,, P139,20,B8,P139_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL175C,AIR2,,"Zinc knuckle protein, involved in nuclear RNA processing and degredation as a component of the TRAMP complex; stimulates the poly(A) polymerase activity of Pap2p in vitro; functionally redundant with Air1p",RNA metabolic process,"transferase activity, nucleotidyltransferase activity","nucleus, nucleolus","RNA metabolic process, nucleotidyltransferase activity, nucleus, transferase activity, transport",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,10,3.4,no,,,,, P139,21,B9,P139_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL176W,,,"Protein of unknown function, predicted by computational methods to be involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; interacts with components of the GID complex; YDL176W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,14,6.5,no,,,,, P139,22,B10,P139_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL177C,,,Putative protein of unknown function; similar to the mouse IMPACT gene; YDL177C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,18,5.6,no,,,,, P139,23,B11,P139_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL178W,DLD2,AIP2,"D-lactate dehydrogenase, located in the mitochondrial matrix",other,"protein binding, oxidoreductase activity","mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity, protein binding",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,224,8,3.6,no,,,,, P139,24,B12,P139_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL179W,PCL9,,"Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (Cdk), expressed in late M/early G1 phase, activated by Swi5p","transcription, cell cycle, RNA metabolic process",enzyme regulator activity,"cellular bud, site of polarized growth","anatomical structure morphogenesis, cellular bud, enzyme regulator activity, other, site of polarized growth",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,100,26,26,no,,,,, P139,25,C1,P139_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL180W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,20,7.5,no,,,,, P139,26,C2,P139_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL181W,INH1,,Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase; inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has similarity to Stf1p; has a calmodulin-binding motif and binds calmodulin in vitro,heterocycle metabolic process,enzyme regulator activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, enzyme regulator activity, membrane, mitochondrial envelope, mitochondrion, other",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,18,7.4,no,,,,, P139,27,C3,P139_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL182W,LYS20,,"Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p",cellular amino acid and derivative metabolic process,transferase activity,"nucleus, mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, nucleus, transferase activity",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,8,3.5,no,,,,, P139,28,C4,P139_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL183C,,,Mitochondrial inner-membrane protein thought to be involved in the formation of an active mitochondrial K+/H+ exchanger (KHE) system; non-essential gene,transport,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,12,3.6,no,,,,, P139,29,C5,P139_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL184C,RPL41A,YL41;L47A;L41A;RPL47A,"Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Bp and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,4,1.8,no,,,,, P139,30,C6,P139_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL185W,TFP1,VMA1;CLS8,"Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease","cellular homeostasis, DNA metabolic process","transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","DNA metabolic process, cellular homeostasis, cytoplasm, hydrolase activity, membrane, other, transporter activity, vacuole",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,310,20,6.5,no,,,,, P139,31,C7,P139_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL186W,,,Putative protein of unknown function; YDL186W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,2,0.6,no,,,,, P139,32,C8,P139_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL187C,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,16,8,no,,,,, P139,33,C9,P139_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL188C,PPH22,PPH2,"Catalytic subunit of protein phosphatase 2A (PP2A), functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis","cell budding, signaling process, cytoskeleton organization, translation, protein modification process, cell cycle","hydrolase activity, phosphoprotein phosphatase activity","nucleus, chromosome","cell budding, cell cycle, chromosome, cytoskeleton organization and biogenesis, hydrolase activity, nucleus, organelle organization and biogenesis, other, phosphoprotein phosphatase activity, protein modification process, translation",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,8,4.1,no,,,,, P139,34,C10,P139_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL189W,RBS1,,"Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; proposed to bind single-stranded nucleic acids via its R3H domain",cellular carbohydrate metabolic process,molecular_function,cytoplasm,"carbohydrate metabolic process, cytoplasm, molecular_function",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,20,6.8,no,,,,, P139,35,C11,P139_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL190C,UFD2,,"Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3","response to stress, protein modification process, cellular protein catabolic process",ligase activity,"nucleus, cytoplasm","cytoplasm, ligase activity, nucleus, protein catabolic process, protein modification process, response to stress",,,4_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,158,4,2.5,no,,,,, P139,36,C12,P139_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL006C,,,,,,,,,,3_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,,,,no,,,,, P139,37,D1,P139_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL023C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,3_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,176,6,3.4,no,,,,, P139,38,D2,P139_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL038C,ATG22,AUT4,Vacuolar integral membrane protein required for efflux of amino acids during autophagic body breakdown in the vacuole; null mutation causes a gradual loss of viability during starvation,transport,molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, membrane, molecular_function, transport, vacuole",,,3_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,286,12,4.2,no,,,,, P139,39,D3,P139_D3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P139,40,D4,P139_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR269C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,1,0.5,no,,,,, P139,41,D5,P139_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR271C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CCC2/YDR270W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,263,5,1.9,no,,,,, P139,42,D6,P139_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR290W,,SWS1,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RTT103",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_6,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,40,16.3,no,,,,, P139,43,D7,P139_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL017W,ATE1,arginyl-tRNA-protein transferase,"Arginyl-tRNA-protein transferase, catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway","protein modification process, cellular protein catabolic process",transferase activity,cytoplasm,"cytoplasm, protein catabolic process, protein modification process, transferase activity",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,185,2,1.1,no,,,,, P139,44,D8,P139_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL020C,GET1,MDM39,Subunit of the GET complex; involved in insertion of proteins into the ER membrane; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance,"transport, mitochondrion organization, response to chemical stimulus, response to stress, vesicle-mediated transport, cellular homeostasis, cellular membrane organization",protein binding,"mitochondrion, membrane, endoplasmic reticulum, cytoplasm","cellular homeostasis, cytoplasm, endoplasmic reticulum, mitochondrion, molecular_function, organelle organization and biogenesis, response to chemical stimulus, response to stress, transport, vesicle-mediated transport",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,294,26,8.8,no,,,,, P139,45,D9,P139_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL023C,PIB2,,"Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27","transport, vesicle-mediated transport",lipid binding,"mitochondrion, cytoplasm","cytoplasm, lipid binding, mitochondrion, vesicle-mediated transport",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,14,4.5,no,,,,, P139,46,D10,P139_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL051W,MST27,,"Putative integral membrane protein, involved in vesicle formation; forms complex with Mst28p; member of DUP240 gene family; binds COPI and COPII vesicles",vesicle organization,protein binding,"membrane, endoplasmic reticulum, plasma membrane, cytoplasm, Golgi apparatus","Golgi apparatus, endoplasmic reticulum, membrane, organelle organization and biogenesis, plasma membrane, protein binding",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,3,1.3,no,,,,, P139,47,D11,P139_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL088W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps snR10, a snoRNA required for preRNA processing",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,3,1.5,no,,,,, P139,48,D12,P139_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL094C,PAN2,,"Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes","response to stress, DNA metabolic process, RNA metabolic process",hydrolase activity,cytoplasm,"DNA metabolic process, RNA metabolic process, cytoplasm, hydrolase activity, response to stress",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,288,10,3.5,no,,,,, P139,49,E1,P139_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL095C,VPS45,VPL28;STT10,"Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment","vacuole organization, transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular homeostasis, cellular membrane organization",protein binding,"endomembrane system, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, organelle organization and biogenesis, other, protein binding, transport, vesicle-mediated transport",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,14,6.4,no,,,,, P139,50,E2,P139_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL096W,TOS8,,Homeodomain-containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; similar to Cup9p transcription factor,biological_process,DNA binding,"nucleus, chromosome","DNA binding, RNA metabolic process, cell cycle, nucleus, transcription, transcription regulator activity",,,7_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,4,1.3,no,,,,, P139,51,E3,P139_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL214W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; deletion mutation phenotype is likely due to the overlapping verified ORF SKI8/YGL213C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,2,0.6,no,,,,, P139,52,E4,P139_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL217C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF KIP3/YGL216W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,2,0.7,no,,,,, P139,53,E5,P139_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL218W,,SRF1,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 93% of ORF overlaps the verified gene MDM34; deletion in cyr1 mutant results in loss of stress resistance",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,178,3,1.7,no,,,,, P139,54,E6,P139_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL235W,,,"Putative protein of unknown function; potential Cdc28p substrate; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,6,2.1,no,,,,, P139,55,E7,P139_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR011W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,2,0.7,no,,,,, P139,56,E8,P139_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR018C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YGR017W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,2,1,no,,,,, P139,57,E9,P139_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR022C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF MTL1/YGR023W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,0,0,no,,,,, P139,58,E10,P139_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR025W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,1,0.5,no,,,,, P139,59,E11,P139_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL006W,YIA6,NDT1,"Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,8,4.1,no,,,,, P139,60,E12,P139_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL007C,NAS2,,Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); similar to mammalian proteasomal modulator subunit; non-essential gene; interacts with Rpn4p,"protein complex biogenesis, cellular protein catabolic process",molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, protein catabolic process",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,8,2.5,no,,,,, P139,61,F1,P139_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL008W,URM1,,"Ubiquitin-like protein with weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature","response to stress, cell budding, response to chemical stimulus, protein modification process, RNA metabolic process",other,"nucleus, cytoplasm","cell budding, cytoplasm, nucleus, other, protein modification process, response to chemical stimulus, response to stress",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,238,10,4.2,no,,,,, P139,62,F2,P139_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL009W,FAA3,,"Long chain fatty acyl-CoA synthetase, activates imported fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery",cellular lipid metabolic process,ligase activity,cellular_component,"cellular_component, ligase activity, lipid metabolic process, protein modification process",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,3,1.6,no,,,,, P139,63,F3,P139_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL010W,DOT5,,Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase during post-diauxic growth,"response to stress, cellular homeostasis, response to chemical stimulus",oxidoreductase activity,nucleus,"cellular homeostasis, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,4,1.8,no,,,,, P139,64,F4,P139_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL014C-A,,YIL015C-A,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,4,1.8,no,,,,, P139,65,F5,P139_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL018W,RPL2B,rp8;YL6;L5B;L2B;LOT2;RPL5A,"Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and has similarity to E. coli L2 and rat L8 ribosomal proteins; expression is upregulated at low temperatures",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, response to chemical stimulus, ribosome, structural molecule activity, translation",,,9_1,,,rg notes: Switched with 5787. cs mixed a and alpha. 08/16/00,DIC:cell structure;YFP:Rad52-YFP protein,,215,9,4.2,no,,,,, P139,66,F6,P139_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL038C,NOT3,,"Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation","transcription, protein modification process, RNA metabolic process",ligase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, ligase activity, nucleus, protein modification process, transcription",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,0,0,no,,,,, P139,67,F7,P139_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL042C,PKP1,,Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p,protein modification process,"transferase activity, protein kinase activity","mitochondrion, cytoplasm","mitochondrion, other, protein kinase activity, protein modification process, transferase activity",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,2,0.6,no,,,,, P139,68,F8,P139_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL047C,SYG1,,Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G-alpha protein deficiency,signaling process,molecular_function,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, molecular_function, plasma membrane, signal transduction",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,7,3.5,no,,,,, P139,69,F9,P139_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL052C,RPL34B,L34B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,268,14,5.2,no,,,,, P139,70,F10,P139_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL054W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,2,1.1,no,,,,, P139,71,F11,P139_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL055C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,5,2.3,no,,,,, P139,72,F12,P139_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL059C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YIL060W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,6,2.9,no,,,,, P139,73,G1,P139_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL060W,,,Putative protein of unknown function; mutant accumulates less glycogen than does wild type; null mutation results in a decrease in plasma membrane electron transport; YIL060W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,3,1.5,no,,,,, P139,74,G2,P139_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL066C,RNR3,RIR3;DIN1,"Minor isoform of the large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits",other,oxidoreductase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,8,2.6,no,,,,, P139,75,G3,P139_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL067C,,,Uncharacterized protein of unknown function,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,10,3.6,no,,,,, P139,76,G4,P139_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL069C,RPS24B,S24B;RPS24EB,Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,5,2.9,no,,,,, P139,77,G5,P139_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL070C,MAM33,,Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation; related to the human complement receptor gC1q-R,"generation of precursor metabolites and energy, cellular respiration",molecular_function,"mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, molecular_function, response to chemical stimulus",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,4,2.2,no,,,,, P139,78,G6,P139_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL071C,PCI8,YIL071W;CSN11;YIH1,"Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain",protein modification process,molecular_function,nucleus,"molecular_function, nucleus, protein modification process",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,265,0,0,no,,,,, P139,79,G7,P139_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL074C,SER33,,"3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p",cellular amino acid and derivative metabolic process,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, oxidoreductase activity",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,2,1.1,no,,,,, P139,80,G8,P139_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL089W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,6,2.2,no,,,,, P139,81,G9,P139_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL092W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,3,1.7,no,,,,, P139,82,G10,P139_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL095W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,6,2.6,no,,,,, P139,83,G11,P139_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL096C,,,Non-essential protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,16,8.2,no,,,,, P139,84,G12,P139_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL098W,BNA4,,"Kynurenine 3-mono oxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; putative therapeutic target for Huntington disease","cofactor metabolic process, vitamin metabolic process",oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, vitamin metabolic process",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,10,3.4,no,,,,, P139,85,H1,P139_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL099W,ATP1,,"Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated","transport, heterocycle metabolic process","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,325,0,0,no,,,,, P139,86,H2,P139_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL100C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the 5' end of ATP1",biological_process,molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,332,2,0.6,no,,,,, P139,87,H3,P139_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P139,88,H4,P139_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL101C,ECM21,ART2,Protein involved in regulating the endocytosis of plasma membrane proteins; identified as a substrate for ubiquitination by Rsp5p and deubiquitination by Ubp2p; promoter contains several Gcn4p binding elements,"transport, fungal-type cell wall organization, vesicle-mediated transport, cellular membrane organization",protein binding,cytoplasm,"cell wall organization and biogenesis, cytoplasm, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,3,1.3,no,,,,, P139,89,H5,P139_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL102W,SFT2,,"Non-essential tetra-spanning membrane protein found mostly in the late Golgi, can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5","transport, vesicle-mediated transport",molecular_function,"membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, membrane, molecular_function, transport, vesicle-mediated transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,4,2,no,,,,, P139,90,H6,P139_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL103C,RTG3,,"Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways","transcription, protein complex biogenesis, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, signal transduction, transcription, transcription regulator activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,2,1,no,,,,, P139,91,H7,P139_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL104C,,YBL103C-A,"Putative protein of unknown function, promoter contains multiple GCN4 binding sites",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,1,0.4,no,,,,, P139,92,H8,P139_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL106C,SRO77,SNI2;SOP2,Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p,"transport, vesicle-mediated transport",molecular_function,"membrane, plasma membrane","molecular_function, plasma membrane, transport, vesicle-mediated transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,6,3,no,,,,, P139,93,H9,P139_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL107C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBL107C is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,0,0,no,,,,, P139,94,H10,P139_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR001C,NTH2,,"Putative neutral trehalase, required for thermotolerance and may mediate resistance to other cellular stresses",cellular carbohydrate metabolic process,hydrolase activity,"mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, hydrolase activity, mitochondrion",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,0,0,no,,,,, P139,95,H11,P139_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR003W,COQ1,,"Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis",cofactor metabolic process,transferase activity,"mitochondrion, cytoplasm","cofactor metabolic process, mitochondrion, transferase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,6,2.9,no,,,,, P139,96,H12,P139_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR005W,RCR1,SSH6,"Protein of the ER membrane involved in cell wall chitin deposition; may function in the endosomal-vacuolar trafficking pathway, helping determine whether plasma membrane proteins are degraded or routed to the plasma membrane","transport, fungal-type cell wall organization, vesicle-mediated transport",molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cell wall organization and biogenesis, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, vesicle-mediated transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,2,0.9,no,,,,, P140,1,A1,P140_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR006W,UGA2,UGA5,Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm,"response to stress, cellular amino acid and derivative metabolic process, response to chemical stimulus",oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, lipid metabolic process, oxidoreductase activity, response to chemical stimulus, response to stress",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,184,1,0.5,no,,,,, P140,2,A2,P140_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR007C,DSF2,,Deletion suppressor of mpt5 mutation,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,7,4,no,,,,, P140,3,A3,P140_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR008C,FLR1,,"Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin","transport, response to chemical stimulus",transporter activity,"membrane, plasma membrane","plasma membrane, response to chemical stimulus, transport, transporter activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,4,1.8,no,,,,, P140,4,A4,P140_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR009C,HHF1,,"Histone H4, core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF2); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity","chromosome organization, protein modification process",DNA binding,"nucleus, chromosome","DNA binding, chromosome, nucleus, organelle organization and biogenesis, protein modification process",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,234,8,3.4,no,,,,, P140,5,A5,P140_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR010W,HHT1,SIN2;BUR5,"Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT2); regulated by acetylation, methylation, and phosphorylation","signaling process, transcription, chromosome organization, cell cycle, RNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, transposition",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,1,0.5,no,,,,, P140,6,A6,P140_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR012C,,,"Dubious open reading frame, unlikely to encode a functional protein; expression induced by iron-regulated transcriptional activator Aft2p",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,0,0,no,,,,, P140,7,A7,P140_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR013C,,,"Putative protein of unknown function, haploid deletion mutant exhibits synthetic phenotype with alpha-synuclein",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,263,1,0.4,no,,,,, P140,8,A8,P140_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR014C,GRX7,,Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; does not bind metal ions; functional overlap with GRX6,"response to stress, response to chemical stimulus","protein binding, oxidoreductase activity","membrane, vacuole, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, membrane, membrane fraction, oxidoreductase activity, protein binding, response to chemical stimulus, response to stress, vacuole",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,4,1.6,no,,,,, P140,9,A9,P140_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR015C,MNN2,LDB8;CRV4;TTP1,"Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, protein modification process, transferase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,4,1.3,no,,,,, P140,10,A10,P140_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR016W,,,"Plasma membrane protein of unknown function, predicted to be palmitoylated; has similarity to hydrophilins, which are hydrophilic, glycine-rich proteins involved in the adaptive response to hyperosmotic conditions",biological_process,molecular_function,"cellular bud, membrane, plasma membrane","molecular_function, plasma membrane, response to stress",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,301,0,0,no,,,,, P140,11,A11,P140_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR018C,GAL7,,"Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism",cellular carbohydrate metabolic process,"transferase activity, nucleotidyltransferase activity",cytoplasm,"carbohydrate metabolic process, cytoplasm, nucleotidyltransferase activity, transferase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,200,5,2.5,no,,,,, P140,12,A12,P140_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR019C,GAL10,,"UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers",cellular carbohydrate metabolic process,isomerase activity,other,"carbohydrate metabolic process, isomerase activity, other",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,207,3,1.4,no,,,,, P140,13,B1,P140_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR020W,GAL1,,"Galactokinase, phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p","cellular carbohydrate metabolic process, transcription, response to chemical stimulus, RNA metabolic process",transferase activity,cytoplasm,"RNA metabolic process, carbohydrate metabolic process, cytoplasm, response to chemical stimulus, transcription, transferase activity, transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,193,1,0.5,no,,,,, P140,14,B2,P140_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR021W,FUR4,,"Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues",transport,transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,244,14,5.7,no,,,,, P140,15,B3,P140_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR022W,POA1,,"Phosphatase that is highly specific for ADP-ribose 1''-phosphate, a tRNA splicing metabolite; may have a role in regulation of tRNA splicing",RNA metabolic process,hydrolase activity,cellular_component,"RNA metabolic process, cellular_component, hydrolase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,200,3,1.5,no,,,,, P140,16,B4,P140_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR023C,CHS3,KTI2;DIT101;CSD2;CAL1,"Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan","cytokinesis, cellular carbohydrate metabolic process, sporulation resulting in formation of a cellular spore, cellular component morphogenesis",transferase activity,"cellular bud, cytoplasmic membrane-bounded vesicle, membrane, site of polarized growth, cytoplasm","carbohydrate metabolic process, cell wall organization and biogenesis, cellular bud, cytokinesis, cytoplasm, cytoplasmic membrane-bounded vesicle, membrane, other, site of polarized growth, sporulation, transferase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,6,3.5,no,,,,, P140,17,B5,P140_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR024W,SCO2,,"Protein anchored to the mitochondrial inner membrane, similar to Sco1p and may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p",transport,oxidoreductase activity,"mitochondrial envelope, mitochondrion, cytoplasm","mitochondrial envelope, mitochondrion, oxidoreductase activity, transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,0,0,no,,,,, P140,18,B6,P140_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR025C,OLA1,,P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; protein levels are induced by hydrogen peroxide,biological_process,hydrolase activity,cytoplasm,"biological_process, cytoplasm, hydrolase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,158,8,5.1,no,,,,, P140,19,B7,P140_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR026C,ETR1,"2-enoyl thioester reductase, E.C. 1.3.1.-;MRF1;MRF1","2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis","cellular lipid metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, cytoplasm","cellular respiration, generation of precursor metabolites and energy, lipid metabolic process, mitochondrion, oxidoreductase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,228,3,1.3,no,,,,, P140,20,B8,P140_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR027C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,197,0,0,no,,,,, P140,21,B9,P140_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR028C,,,"Putative protein kinase, possible substrate of cAMP-dependent protein kinase (PKA)",biological_process,"transferase activity, protein kinase activity",cytoplasm,"biological_process, cytoplasm, protein kinase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,4,1.8,no,,,,, P140,22,B10,P140_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR030W,RKM3,,Ribosomal lysine methyltransferase specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); nuclear SET domain containing protein,protein modification process,transferase activity,nucleus,"lipid metabolic process, molecular_function, nucleus",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,235,1,0.4,no,,,,, P140,23,B11,P140_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR031W,RPL4A,rp2;YL2;L4A;L2A,"N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Bp and has similarity to E. coli L4 and rat L4 ribosomal proteins",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,1,0.4,no,,,,, P140,24,B12,P140_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR032W,,,"Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,233,1,0.4,no,,,,, P140,25,C1,P140_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR033W,EDS1,,Putative zinc cluster protein; YBR033W is not an essential gene,biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,8,3.8,no,,,,, P140,26,C2,P140_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR034C,HMT1,RMT1;ODP1;HCP1,"Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, affecting their activity and nuclear export; methylates U1 snRNP protein Snp1p and ribosomal protein Rps2p","transport, transcription, protein modification process, RNA metabolic process",transferase activity,nucleus,"nucleus, protein modification process, ribosome biogenesis, transferase activity, transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,4,2.1,no,,,,, P140,27,C3,P140_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR035C,PDX3,,"Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism",cellular lipid metabolic process,oxidoreductase activity,cellular_component,"cellular_component, lipid metabolic process, oxidoreductase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,170,1,0.6,no,,,,, P140,28,C4,P140_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR036C,CSG2,CLS2,"Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations","cellular lipid metabolic process, cellular homeostasis",enzyme regulator activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cellular homeostasis, cytoplasm, endomembrane system, endoplasmic reticulum, enzyme regulator activity, lipid metabolic process, membrane, response to chemical stimulus",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,3,1.3,no,,,,, P140,29,C5,P140_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR037C,SCO1,PET161,"Copper-binding protein of the mitochondrial inner membrane, required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; has similarity to thioredoxins","transport, response to chemical stimulus, protein complex biogenesis",oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, other, oxidoreductase activity, response to chemical stimulus, response to stress, transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,239,4,1.7,no,,,,, P140,30,C6,P140_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR040W,FIG1,,"Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating","conjugation, cellular component morphogenesis, response to chemical stimulus",molecular_function,"cell wall, site of polarized growth","anatomical structure morphogenesis, cell wall, conjugation, molecular_function, response to chemical stimulus, site of polarized growth",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,302,0,0,no,,,,, P140,31,C7,P140_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR041W,FAT1,,Very long chain fatty acyl-CoA synthetase and long chain fatty acid transporter; activates imported fatty acids with a preference for very long lengths (C20-C26); has a separate function in the transport of long chain fatty acids,"transport, cellular lipid metabolic process","ligase activity, transporter activity","peroxisome, membrane, endoplasmic reticulum, cytoplasm, plasma membrane","cytoplasm, ligase activity, lipid metabolic process, membrane, membrane fraction, peroxisome, plasma membrane, transport, transporter activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,226,0,0,no,,,,, P140,32,C8,P140_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR042C,CST26,PSI1,Protein required for incorporation of stearic acid into phosphatidylinositol; affects chromosome stability when overexpressed,cellular lipid metabolic process,transferase activity,cytoplasm,"cytoplasm, lipid metabolic process, transferase activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,1,0.5,no,,,,, P140,33,C9,P140_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR043C,QDR3,AQR2,"Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin","transport, response to chemical stimulus",transporter activity,"membrane, plasma membrane","plasma membrane, response to chemical stimulus, transport, transporter activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,1,0.5,no,,,,, P140,34,C10,P140_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR044C,TCM62,,Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone,"mitochondrion organization, protein complex biogenesis",protein binding,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, protein binding",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,4,1.8,no,,,,, P140,35,C11,P140_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR045C,GIP1,,"Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p","sporulation resulting in formation of a cellular spore, cellular component morphogenesis","protein binding, enzyme regulator activity","membrane, cytoplasm","cell wall organization and biogenesis, cytoplasm, enzyme regulator activity, membrane, other, protein binding, sporulation",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,216,6,2.8,no,,,,, P140,36,C12,P140_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR046C,ZTA1,,"NADPH-dependent quinone reductase, GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin","response to stress, response to chemical stimulus","RNA binding, oxidoreductase activity","nucleus, cytoplasm","RNA binding, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,213,2,0.9,no,,,,, P140,37,D1,P140_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR047W,FMP23,,"Putative protein of unknown function; proposed to be involved in iron or copper homeostasis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,1,0.5,no,,,,, P140,38,D2,P140_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR048W,RPS11B,rp41B;YS12;S18B;S11B,Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,5,2.7,no,,,,, P140,39,D3,P140_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR050C,REG2,,"Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease","transcription, RNA metabolic process",enzyme regulator activity,cytoplasm,"RNA metabolic process, cytoplasm, enzyme regulator activity, transcription",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,2,1,no,,,,, P140,40,D4,P140_D4,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P140,41,D5,P140_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR051W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partiallly overlaps the REG2/YBR050C regulatory subunit of the Glc7p type-1 protein phosphatase",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,4,1.2,no,,,,, P140,42,D6,P140_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR052C,RFS1,,Protein of unknown function; member of a flavodoxin-like fold protein family that includes Pst2p and Ycp4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern,biological_process,molecular_function,"membrane, cytoplasm","biological_process, cytoplasm, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,0,0,no,,,,, P140,43,D7,P140_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR053C,,,Putative protein of unknown function; induced by cell wall perturbation,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,2,0.7,no,,,,, P140,44,D8,P140_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR054W,YRO2,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; transcriptionally regulated by Haa1p",biological_process,molecular_function,"cellular bud, mitochondrion, cytoplasm","biological_process, cellular bud, mitochondrion, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,2,1.2,no,,,,, P140,45,D9,P140_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR056W,,,Putative cytoplasmic protein of unknown function,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,330,6,1.8,no,,,,, P140,46,D10,P140_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR057C,MUM2,SPOT8,"Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, which is a component of the origin recognition complex",DNA metabolic process,molecular_function,cytoplasm,"DNA metabolic process, cytoplasm, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,3,1.7,no,,,,, P140,47,D11,P140_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR058C,UBP14,GID6,"Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T","cellular carbohydrate metabolic process, protein modification process, cellular protein catabolic process","peptidase activity, hydrolase activity",cytoplasm,"carbohydrate metabolic process, cytoplasm, hydrolase activity, peptidase activity, protein catabolic process, protein modification process, response to chemical stimulus",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,288,8,2.8,no,,,,, P140,48,D12,P140_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR059C,AKL1,,"Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization","transport, cytoskeleton organization, vesicle-mediated transport, cellular membrane organization","transferase activity, protein kinase activity","cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoplasm, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, protein kinase activity, site of polarized growth, transport, vesicle-mediated transport",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,256,16,6.3,no,,,,, P140,49,E1,P140_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR062C,,,Hypothetical protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,4,2,no,,,,, P140,50,E2,P140_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR063C,,,Putative protein of unknown function; YBR063C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,9,4.6,no,,,,, P140,51,E3,P140_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR064W,,,Dubious open reading frame unlikely to encode a protein; partially overlaps the uncharacterized ORF YBR063C,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,270,3,1.1,no,,,,, P140,52,E4,P140_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR065C,ECM2,SLT11,"Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p","fungal-type cell wall organization, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, cell wall organization and biogenesis, molecular_function, nucleus",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,4,2.3,no,,,,, P140,53,E5,P140_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR066C,NRG2,,Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p,pseudohyphal growth,transcription regulator activity,nucleus,"nucleus, other, pseudohyphal growth, transcription regulator activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,238,6,2.5,no,,,,, P140,54,E6,P140_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR067C,TIP1,,Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins,fungal-type cell wall organization,"structural molecule activity, hydrolase activity",cell wall,"cell wall, cell wall organization and biogenesis, hydrolase activity, structural molecule activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,178,1,0.6,no,,,,, P140,55,E7,P140_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR068C,BAP2,,"High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,3,1.3,no,,,,, P140,56,E8,P140_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR069C,TAT1,VAP1;TAP1,"Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,8,3.3,no,,,,, P140,57,E9,P140_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR071W,,,Putative protein of unknown function; (GFP)-fusion and epitope-tagged proteins localize to the cytoplasm; mRNA expression may be regulated by the cell cycle and/or cell wall stress,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,14,4.7,no,,,,, P140,58,E10,P140_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR072W,HSP26,,"Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; oligomer activation requires a heat-induced conformational change; not expressed in unstressed cells","response to stress, protein folding",protein binding,"nucleus, cytoplasm","cytoplasm, nucleus, protein binding, protein folding, response to stress",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,9,4.6,no,,,,, P140,59,E11,P140_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR073W,RDH54,TID1,"DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference","chromosome segregation, response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process","hydrolase activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, response to stress",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,223,10,4.5,no,,,,, P140,60,E12,P140_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR074W,,YBR075W,Putative metalloprotease,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,202,6,3,no,,,,, P140,61,F1,P140_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR074W,,YBR075W,Putative metalloprotease,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,4,2.2,no,,,,, P140,62,F2,P140_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR076W,ECM8,,Non-essential protein of unknown function,fungal-type cell wall organization,molecular_function,cellular_component,"cell wall organization and biogenesis, cellular_component, molecular_function",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,7,4.1,no,,,,, P140,63,F3,P140_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR077C,SLM4,GSE1;NIR1;EGO3,"Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; gene exhibits synthetic genetic interaction with MSS4","signaling process, cellular membrane organization",lipid binding,"membrane, vacuole, cytoplasm","cytoplasm, lipid binding, membrane, membrane organization and biogenesis, response to chemical stimulus, signal transduction, vacuole",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,4,2.1,no,,,,, P140,64,F4,P140_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR078W,ECM33,,"GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p",fungal-type cell wall organization,molecular_function,"membrane fraction, mitochondrion, cell wall, membrane, cytoplasm, plasma membrane","cell wall, cell wall organization and biogenesis, membrane fraction, mitochondrion, molecular_function, plasma membrane",,,2_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,1,0.5,no,,,,, P140,65,F5,P140_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL001W,DOM34,,"Endoribonuclease; functions in no-go mRNA decay, protein translation to promote G1 progression and differentiation, required for meiotic cell division; similar to the eukaryotic Pelota","translation, meiosis, sporulation resulting in formation of a cellular spore, pseudohyphal growth, cell cycle, RNA metabolic process",hydrolase activity,cytoplasm,"RNA metabolic process, cytoplasm, hydrolase activity, meiosis, pseudohyphal growth, sporulation, translation",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,203,1,0.5,no,,,,, P140,66,F6,P140_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL003C,PET8,SAM5,"S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,328,2,0.6,no,,,,, P140,67,F7,P140_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL004W,HRB1,TOM34,"Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p",transport,RNA binding,"nucleus, cytoplasm","RNA binding, cytoplasm, nucleus, transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,4,1.8,no,,,,, P140,68,F8,P140_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL005C,MRP7,YmL23;MRPL2,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation","transferase activity, structural molecule activity","ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, transferase activity, translation",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,3,1.5,no,,,,, P140,69,F9,P140_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL008C,ASI3,,Putative integral membrane E3 ubiquitin ligase; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals,cellular protein catabolic process,ligase activity,"nucleus, membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, ligase activity, membrane, nucleus, protein catabolic process",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,3,1.6,no,,,,, P140,70,F10,P140_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL009W,IDP3,,"Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids","cofactor metabolic process, cellular lipid metabolic process",oxidoreductase activity,"peroxisome, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, lipid metabolic process, mitochondrion, other, oxidoreductase activity, peroxisome, vitamin metabolic process",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,3,1.6,no,,,,, P140,71,F11,P140_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL010W,,,Putative protein of unknown function with similarity to phosphoserine phosphatases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant shows an increase in glycogen accumulation,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,215,2,0.9,no,,,,, P140,72,F12,P140_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL011C,,,Putative protein of unknown function; YNL011C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,234,0,0,no,,,,, P140,73,G1,P140_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL012W,SPO1,,Meiosis-specific prospore protein; required for meiotic spindle pole body duplication and separation; required to produce bending force necessary for proper prospore membrane assembly during sporulation; has similarity to phospholipase B,"meiosis, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cell cycle, cellular membrane organization",hydrolase activity,"nucleus, membrane, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, meiosis, nucleus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,1,0.4,no,,,,, P140,74,G2,P140_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL013C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF HEF3/YNL014W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,8,2.7,no,,,,, P140,75,G3,P140_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL014W,HEF3,ZRG7,Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells,translation,"RNA binding, hydrolase activity","ribosome, cytoplasm","cytoplasm, hydrolase activity, ribosome, translation, translation regulator activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,4,1.3,no,,,,, P140,76,G4,P140_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL015W,PBI2,IB2;I2B;LMA1,"Cytosolic inhibitor of vacuolar proteinase B (PRB1), required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion","vacuole organization, cellular membrane organization",enzyme regulator activity,"vacuole, cytoplasm","cytoplasm, enzyme regulator activity, membrane organization and biogenesis, organelle organization and biogenesis, other, vacuole",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,2,0.9,no,,,,, P140,77,G5,P140_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL016W,PUB1,RNP1,"Poly (A)+ RNA-binding protein, abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly",RNA metabolic process,RNA binding,"nucleus, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, nucleus, other",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,8,2.5,no,,,,, P140,78,G6,P140_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL020C,ARK1,,Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis,"transport, cytoskeleton organization, cytokinesis, protein modification process, vesicle-mediated transport, cellular membrane organization","transferase activity, protein kinase activity","cell cortex, cytoskeleton, site of polarized growth, cytoplasm","cell cortex, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, protein kinase activity, protein modification process, transferase activity, transport, vesicle-mediated transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,8,2.6,no,,,,, P140,79,G7,P140_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL021W,HDA1,,"Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation","response to stress, chromosome organization, transcription, protein modification process, RNA metabolic process",hydrolase activity,"nucleus, chromosome","RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, other, protein modification process, transcription",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,300,2,0.7,no,,,,, P140,80,G8,P140_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL022C,,,"Putative cytosine 5-methyltransferase, contains seven beta-strand methyltransferase motif similar to NOP2/YNL061W; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; predicted to be involved in ribosome biogenesis",biological_process,transferase activity,nucleus,"molecular_function, nucleus, ribosome biogenesis",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,10,3,no,,,,, P140,81,G9,P140_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL023C,FAP1,,"Protein that binds to Fpr1p, conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; accumulates in the nucleus upon treatment of cells with rapamycin; has similarity to D. melanogaster shuttle craft and human NFX1",biological_process,other,cytoplasm,"DNA binding, biological_process, cellular_component, transcription regulator activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,144,8,5.6,no,,,,, P140,82,G10,P140_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL024C,,,Putative protein of unknown function with seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL024C is not an essential gene,biological_process,transferase activity,cytoplasm,"biological_process, cytoplasm, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,338,6,1.8,no,,,,, P140,83,G11,P140_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL025C,SSN8,CycC;RYE2;UME3;SRB11;NUT9;GIG3,"Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance","meiosis, transcription, cell cycle, RNA metabolic process","transcription regulator activity, enzyme regulator activity",nucleus,"RNA metabolic process, enzyme regulator activity, meiosis, nucleus, transcription, transcription regulator activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,196,1,0.5,no,,,,, P140,84,G12,P140_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL027W,CRZ1,TCN1;HAL8,Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation,"signaling process, transcription, RNA metabolic process",DNA binding,"nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, nucleus, signal transduction, transcription, transcription regulator activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,235,6,2.6,no,,,,, P140,85,H1,P140_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL028W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,240,3,1.3,no,,,,, P140,86,H2,P140_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL029C,KTR5,,Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family,"fungal-type cell wall organization, cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cell wall organization and biogenesis, protein modification process, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,323,0,0,no,,,,, P140,87,H3,P140_H3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,,,,,,,,,,,,,,,,DIC:cell structure;YFP:Rad52-YFP protein,no annotation but image available,,,,,,,,, P140,88,H4,P140_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL030W,HHF2,,"Histone H4, core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF1); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity","chromosome organization, protein modification process",DNA binding,"nucleus, chromosome","DNA binding, chromosome, nucleus, organelle organization and biogenesis, protein modification process",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,12,4.2,no,,,,, P140,89,H5,P140_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL031C,HHT2,,"Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT1); regulated by acetylation, methylation, and phosphorylation","signaling process, transcription, chromosome organization, cell cycle, RNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, chromosome, nucleus, organelle organization and biogenesis",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,12,4.2,no,,,,, P140,90,H6,P140_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL032W,SIW14,OCA3,Tyrosine phosphatase that plays a role in actin filament organization and endocytosis; localized to the cytoplasm,"transport, cytoskeleton organization, protein modification process, response to stress, vesicle-mediated transport, cellular membrane organization","hydrolase activity, phosphoprotein phosphatase activity",cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, hydrolase activity, membrane organization and biogenesis, organelle organization and biogenesis, phosphoprotein phosphatase activity, protein modification process, response to stress, transport, vesicle-mediated transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,198,2,1,no,,,,, P140,91,H7,P140_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL034W,,,Putative protein of unknown function; YNL034W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,3,1.5,no,,,,, P140,92,H8,P140_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL035C,,,Putative protein of unknown function with similarity to proteins containing WD-40 domains; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YNL035C is not an essential gene,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,185,2,1.1,no,,,,, P140,93,H9,P140_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL037C,IDH1,,"Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle","cofactor metabolic process, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, other, oxidoreductase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,2,1.1,no,,,,, P140,94,H10,P140_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL040W,,,Putative protein of unknown function with strong similarity to alanyl-tRNA synthases from Eubacteria; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL040W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,319,0,0,no,,,,, P140,95,H11,P140_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL041C,COG6,SEC37;COD2,"Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","transport, vesicle-mediated transport",molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, molecular_function, transport, vesicle-mediated transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,332,6,1.8,no,,,,, P140,96,H12,P140_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL042W,BOP3,,"Protein of unknown function, potential Cdc28p substrate; overproduction confers resistance to methylmercury",response to chemical stimulus,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, response to chemical stimulus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,225,0,0,no,,,,, P141,1,A1,P141_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL043C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YIP3/YNL044W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,12,5.6,no,,,,, P141,2,A2,P141_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL044W,YIP3,,"Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p","transport, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, endoplasmic reticulum, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endoplasmic reticulum, molecular_function, transport, vesicle-mediated transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,7,3,no,,,,, P141,3,A3,P141_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL045W,LAP2,,"Leucyl aminopeptidase yscIV (leukotriene A4 hydrolase) with epoxide hydrolase activity, metalloenzyme containing one zinc atom; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus",cellular lipid metabolic process,"peptidase activity, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, lipid metabolic process, nucleus, peptidase activity, protein catabolic process",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,2,0.8,no,,,,, P141,4,A4,P141_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL046W,,,Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO),biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, response to chemical stimulus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,6,1.9,no,,,,, P141,5,A5,P141_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL049C,SFB2,ISS1,"Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat, required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sec24p and Sfb3p","transport, vesicle-mediated transport, vesicle organization, protein complex biogenesis, cellular membrane organization",other,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, transport, vesicle-mediated transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,18,6.4,no,,,,, P141,6,A6,P141_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL050C,,,Putative protein of unknown function; YNL050c is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,4,2,no,,,,, P141,7,A7,P141_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR001C,CIT1,LYS6;CS1,"Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein","cofactor metabolic process, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy, cellular respiration",transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cellular respiration, cofactor metabolic process, generation of precursor metabolites and energy, mitochondrion, other, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,4,2.1,no,,,,, P141,8,A8,P141_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR002C,ATO2,FUN34,"Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, other, plasma membrane, transport, transporter activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,7,3.6,no,,,,, P141,9,A9,P141_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR004W,SWM2,,Putative protein of unknown function; haploid disruptant exhibits cold-sensitive growth and elongated buds,biological_process,molecular_function,"nucleus, nucleolus","biological_process, molecular_function, nucleolus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,15,6.6,no,,,,, P141,10,A10,P141_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR005C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,0,0,no,,,,, P141,11,A11,P141_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR006W,VPS27,DID7;VPT27;VPL23;SSV17;GRD11,"Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)","transport, vesicle-mediated transport","protein binding, lipid binding",cytoplasm,"cytoplasm, lipid binding, other, protein binding, transport, vesicle-mediated transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,8,4,no,,,,, P141,12,A12,P141_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR007C,ATG3,AUT1;APG3,"E2-like enzyme involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy and Cvt","vacuole organization, transport, response to stress, protein modification process, cellular membrane organization",ligase activity,cytoplasm,"cytoplasm, ligase activity, membrane organization and biogenesis, organelle organization and biogenesis, protein modification process, response to stress, transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,6,2.7,no,,,,, P141,13,B1,P141_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR008W,LRO1,,Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that contribute to triglyceride synthesis; putative homolog of human lecithin cholesterol acyltransferase,cellular lipid metabolic process,transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,6,3,no,,,,, P141,14,B2,P141_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR009W,NRM1,,Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase,transcription,transcription regulator activity,"nucleus, cytoplasm","cytoplasm, nucleus, transcription, transcription regulator activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,2,1,no,,,,, P141,15,B3,P141_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR010W,CSE2,MED9,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; component of the Med9/10 module; required for regulation of RNA polymerase II activity,"chromosome organization, transcription, cell cycle, chromosome segregation, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, cell cycle, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity, transposition",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,12,4.5,no,,,,, P141,16,B4,P141_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR012W,URK1,,"Uridine/cytidine kinase, component of the pyrimidine ribonucleotide salvage pathway that converts uridine into UMP and cytidine into CMP; involved in the pyrimidine deoxyribonucleotide salvage pathway, converting deoxycytidine into dCMP",other,transferase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, nucleus, ribosome biogenesis, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,20,10.8,no,,,,, P141,17,B5,P141_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR013C,PHO91,,"Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth",transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, other, transport, transporter activity, vacuole",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,8,4,no,,,,, P141,18,B6,P141_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR014W,,,"Putative protein of unknown function; expression is cell-cycle regulated, Azf1p-dependent, and heat-inducible",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,10,3.5,no,,,,, P141,19,B7,P141_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR015W,SMM1,DUS2,"Dihydrouridine synthase, member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs",RNA metabolic process,oxidoreductase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, oxidoreductase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,26,8.4,no,,,,, P141,20,B8,P141_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR018W,AIM38,,Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; may interact with respiratory chain complex IV; null mutant is viable and displays reduced frequency of mitochondrial genome loss,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,2,1.1,no,,,,, P141,21,B9,P141_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR019W,ARE2,SAT1,"Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen",other,transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,13,5.5,no,,,,, P141,22,B10,P141_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR020C,ATP23,,"Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex",protein complex biogenesis,"peptidase activity, hydrolase activity","membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, other, peptidase activity, protein modification process",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,5,2.2,no,,,,, P141,23,B11,P141_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR021W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNR021W is not an essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,8,2.5,no,,,,, P141,24,B12,P141_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR022C,MRPL50,,"Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,12,5.9,no,,,,, P141,25,C1,P141_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR023W,SNF12,SWP73,73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive,chromosome organization,transcription regulator activity,nucleus,"nucleus, organelle organization and biogenesis, transcription regulator activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,14,6.9,no,,,,, P141,26,C2,P141_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR024W,MPP6,,"Nuclear exosome-associated RNA binding protein; involved in surveillance of pre-rRNAs and pre-mRNAs, and the degradation of cryptic non-coding RNAs (ncRNA); copurifies with ribosomes","ribosome biogenesis, RNA metabolic process",RNA binding,"nucleus, ribosome, cytoplasm","RNA binding, RNA metabolic process, nucleus, ribosome",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,15,7.7,no,,,,, P141,27,C3,P141_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR025C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; deletion reduces expression of PIS1 gene encoding phosphatidylinositol synthase",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,2,0.6,no,,,,, P141,28,C4,P141_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR027W,BUD17,,"Putative pyridoxal kinase, a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK)","cofactor metabolic process, cytokinesis, vitamin metabolic process, heterocycle metabolic process, cell cycle",transferase activity,"nucleus, cytoplasm","anatomical structure morphogenesis, cytokinesis, cytoplasm, molecular_function, nucleus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,8,3.9,no,,,,, P141,29,C5,P141_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR028W,CPR8,,"Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; similarity to Cpr4p suggests a potential role in the secretory pathway",biological_process,isomerase activity,"vacuole, cytoplasm","biological_process, cytoplasm, isomerase activity, vacuole",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,18,5.5,no,,,,, P141,30,C6,P141_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR029C,,,"Putative protein of unknown function, deletion confers reduced fitness in saline",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,6,2.9,no,,,,, P141,31,C7,P141_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR030W,ALG12,ECM39,"Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation","cellular carbohydrate metabolic process, protein modification process",transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, protein modification process, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,3,1.2,no,,,,, P141,32,C8,P141_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR031C,SSK2,,"MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress","signaling process, cytoskeleton organization, protein modification process, response to stress","transferase activity, protein kinase activity, signal transducer activity","cellular bud, site of polarized growth, cytoplasm","DNA metabolic process, cellular bud, cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein kinase activity, protein modification process, response to stress, signal transducer activity, signal transduction, site of polarized growth, transferase activity, transposition",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,26,8,no,,,,, P141,33,C9,P141_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR032W,PPG1,,"Putative serine/threonine protein phosphatase of the type 2A-like phosphatase family, required for glycogen accumulation; interacts with Tap42p, which binds to and regulates other protein phosphatases","cellular carbohydrate metabolic process, generation of precursor metabolites and energy, protein modification process","phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,3,1.5,no,,,,, P141,34,C10,P141_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR033W,ABZ1,,"Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB; required for the synthesis of para-aminobenzoic acid, an important intermediate for folate and ubiquinone Q biosynthesis","cofactor metabolic process, cellular amino acid and derivative metabolic process, vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cytoplasm,"aromatic compound metabolic process, cofactor metabolic process, cytoplasm, heterocycle metabolic process, ligase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,8,3.8,no,,,,, P141,35,C11,P141_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR034W,SOL1,,"Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol2p, Sol3p, and Sol4p",transport,"molecular_function, hydrolase activity","nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,328,12,3.7,no,,,,, P141,36,C12,P141_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR036C,MRPS12,,Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,0,0,no,,,,, P141,37,D1,P141_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR037C,RSM19,,"Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S19 ribosomal protein","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,14,5.8,no,,,,, P141,38,D2,P141_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR039C,ZRG17,,"Endoplasmic reticulum protein of unknown function, transcription is induced under conditions of zinc deficiency; mutant phenotype suggests a role in uptake of zinc",transport,transporter activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, transport, transporter activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,1,0.5,no,,,,, P141,39,D3,P141_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR040W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,9,4,no,,,,, P141,40,D4,P141_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR041C,COQ2,,"Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis",cofactor metabolic process,transferase activity,"membrane, membrane fraction, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cofactor metabolic process, cytoplasm, endomembrane system, membrane, membrane fraction, mitochondrion, transferase activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,16,6.8,no,,,,, P141,41,D5,P141_D5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P141,42,D6,P141_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR042W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene COQ2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,10,4.8,no,,,,, P141,43,D7,P141_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR044W,AGA1,a-agglutinin anchorage subunit,"Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds","conjugation, response to chemical stimulus",protein binding,cell wall,"cell wall, conjugation, protein binding, response to chemical stimulus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,16,5.3,no,,,,, P141,44,D8,P141_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR045W,PET494,,"Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet122p; located in the mitochondrial inner membrane","mitochondrion organization, translation",translation regulator activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, translation, translation regulator activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,12,4.9,no,,,,, P141,45,D9,P141_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR047W,FPK1,,"Ser/Thr protein kinase that regulates the putative phospholipid translocases Lem3p-Dnf1p/Dnf2p; phosphorylates and inhibits upstream inhibitory kinase, Ypk1p; localizes to the cytoplasm, early endosome/TGN compartments, and plasma membrane","transport, response to chemical stimulus, protein modification process, cellular membrane organization","transferase activity, protein kinase activity","membrane, cytoplasm, plasma membrane","cytoplasm, protein kinase activity, response to chemical stimulus",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,4,1.7,no,,,,, P141,46,D10,P141_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR048W,,CRF1,"Protein that interacts specifically in vivo with phospholipid translocase (flippase) Dnf3p; similar to Cdc50p, which is an essential interaction partner of the flippase Drs2p",response to chemical stimulus,"transporter activity, hydrolase activity",membrane,"hydrolase activity, membrane, response to chemical stimulus, transporter activity",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,201,3,1.5,no,,,,, P141,47,D11,P141_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR049C,MSO1,,"Probable component of the secretory vesicle docking complex, acts at a late step in secretion; shows genetic and physical interactions with Sec1p; required for prospore membrane formation during sporulation","transport, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cellular membrane organization",molecular_function,"membrane fraction, cellular bud, membrane, site of polarized growth, plasma membrane","membrane fraction, molecular_function, sporulation, transport, vesicle-mediated transport",,,14_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,6,2.9,no,,,,, P141,48,D12,P141_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL146W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNL146W is not an essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,223,2,0.9,no,,,,, P141,49,E1,P141_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL145W,MFA2,,"Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1","signaling process, conjugation, response to chemical stimulus",protein binding,extracellular region,"conjugation, extracellular region, protein binding, response to chemical stimulus, signal transduction",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,56,21.4,no,,,,, P141,50,E2,P141_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL144C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YNL144C is not an essential gene",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,5,2.1,no,,,,, P141,51,E3,P141_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL143C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,18,9.2,no,,,,, P141,52,E4,P141_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL141W,AAH1,,"Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome","heterocycle metabolic process, cellular aromatic compound metabolic process",hydrolase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, hydrolase activity, nucleus, other, ribosome biogenesis",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,20,10,no,,,,, P141,53,E5,P141_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL136W,EAF7,,"Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A","response to stress, chromosome organization, transcription, DNA metabolic process, protein modification process, RNA metabolic process",molecular_function,nucleus,"DNA metabolic process, RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, protein modification process, response to stress, transcription",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,18,6.3,no,,,,, P141,54,E6,P141_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL135C,FPR1,RBP1;FKB1,"Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function","protein folding, chromosome organization, cellular amino acid and derivative metabolic process",isomerase activity,"nucleus, mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, isomerase activity, mitochondrion, nucleus, organelle organization and biogenesis",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,4,2.3,no,,,,, P141,55,E7,P141_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL134C,,,Putative protein of unknown function with similarity to dehydrogenases from other model organisms; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced by the DNA-damaging agent MMS,biological_process,oxidoreductase activity,"nucleus, cytoplasm","biological_process, cytoplasm, nucleus, oxidoreductase activity",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,148,10,6.8,no,,,,, P141,56,E8,P141_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL133C,FYV6,,"Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining","response to stress, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, molecular_function, nucleus, response to stress",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,184,2,1.1,no,,,,, P141,57,E9,P141_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL129W,NRK1,,"Nicotinamide riboside kinase, catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis","cofactor metabolic process, vitamin metabolic process",transferase activity,cytoplasm,"cofactor metabolic process, cytoplasm, transferase activity, vitamin metabolic process",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,8,2.6,no,,,,, P141,58,E10,P141_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL128W,TEP1,,Homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 that has lipid phosphatase activity and is linked to the phosphatidylinositol signaling pathway; plays a role in normal sporulation,"sporulation resulting in formation of a cellular spore, signaling process, cellular lipid metabolic process, cellular component morphogenesis",hydrolase activity,cellular_component,"cell wall organization and biogenesis, cellular_component, hydrolase activity, lipid metabolic process, signal transduction, sporulation",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,26,9.2,no,,,,, P141,59,E11,P141_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL127W,FAR11,,"Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far10p; has similarity to the N- and C-termini of N. crassa HAM-2","conjugation, cell cycle, response to chemical stimulus",molecular_function,cellular_component,"cell cycle, cellular_component, conjugation, molecular_function, response to chemical stimulus",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,9,4.9,no,,,,, P141,60,E12,P141_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL123W,NMA111,YNM3,Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases,"response to stress, cellular lipid metabolic process","peptidase activity, hydrolase activity",nucleus,"hydrolase activity, lipid metabolic process, nucleus, other, peptidase activity",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,4,1.9,no,,,,, P141,61,F1,P141_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL122C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL122C is not an essential gene,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,20,7.1,no,,,,, P141,62,F2,P141_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL117W,MLS1,,"Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium",cellular carbohydrate metabolic process,transferase activity,"peroxisome, cytoplasm","carbohydrate metabolic process, cytoplasm, peroxisome, transferase activity",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,11,5.1,no,,,,, P141,63,F3,P141_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL116W,DMA2,CHF2,"Protein involved in ubiquitination; plays a role in regulating spindle position and orientation; functionally redundant with Dma1p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr","signaling process, cytoskeleton organization, cell cycle, protein modification process, protein complex biogenesis",ligase activity,cytoplasm,"cell cycle, cytoplasm, cytoskeleton organization and biogenesis, ligase activity, organelle organization and biogenesis, protein modification process",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,8,4.2,no,,,,, P141,64,F4,P141_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL108C,,HUF,Putative protein of unknown function with similarity to Tfc7p and prokaryotic phosphotransfer enzymes; null mutant shows alterations in glucose metabolism; GFP-fusion protein localizes to the cytoplasm and nucleus,biological_process,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, other",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,9,4.2,no,,,,, P141,65,F5,P141_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL101W,AVT4,,"Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters",transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,18,5.6,no,,,,, P141,66,F6,P141_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL098C,RAS2,TSL7;GLC5;CYR3;CTN5,"GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes","signaling process, transcription, heterocycle metabolic process, response to chemical stimulus, sporulation resulting in formation of a cellular spore, pseudohyphal growth, RNA metabolic process",hydrolase activity,"membrane fraction, membrane, plasma membrane","RNA metabolic process, hydrolase activity, other, plasma membrane, pseudohyphal growth, response to chemical stimulus, signal transduction, sporulation, transcription",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,11,6.5,no,,,,, P141,67,F7,P141_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL094W,APP1,,"Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-protein interactions in large-scale studies suggests a possible role in actin filament organization",cytoskeleton organization,molecular_function,"cell cortex, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, molecular_function, organelle organization and biogenesis",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,9,4.2,no,,,,, P141,68,F8,P141_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL092W,,,Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; YNL092W is not an essential gene,biological_process,transferase activity,cellular_component,"biological_process, cellular_component, transferase activity",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,12,3.6,no,,,,, P141,69,F9,P141_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL084C,END3,,"EH domain-containing protein involved in endocytosis, actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p","transport, cell budding, cytoskeleton organization, cytokinesis, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cell cycle, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cell wall organization and biogenesis, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, sporulation, transport, vesicle-mediated transport",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,6,1.8,no,,,,, P141,70,F10,P141_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL081C,SWS2,,"Putative mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S13 ribosomal protein; participates in controlling sporulation efficiency","sporulation resulting in formation of a cellular spore, mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, sporulation, structural molecule activity, translation",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,20,6.8,no,,,,, P141,71,F11,P141_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL077W,APJ1,,"Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,protein binding,"nucleus, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, nucleus, protein binding",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,217,2,0.9,no,,,,, P141,72,F12,P141_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL064C,YDJ1,HSP40;MAS5,Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein translocation across membranes; member of the DnaJ family,"transport, protein folding, mitochondrion organization, cellular protein catabolic process","protein binding, enzyme regulator activity","membrane fraction, cytoplasm","cytoplasm, enzyme regulator activity, membrane fraction, organelle organization and biogenesis, other, protein binding, protein catabolic process, protein folding, response to chemical stimulus, transport",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,265,0,0,no,,,,, P141,73,G1,P141_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL063W,MTQ1,,S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene,translation,transferase activity,"mitochondrion, cytoplasm","mitochondrion, transferase activity, translation",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,4,2.2,no,,,,, P141,74,G2,P141_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL057W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,8,3.8,no,,,,, P141,75,G3,P141_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL058C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,26,13.8,no,,,,, P141,76,G4,P141_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL054W,VAC7,,Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock,cellular lipid metabolic process,molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, enzyme regulator activity, lipid metabolic process, membrane, organelle organization and biogenesis, vacuole",,,14_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,28,8.3,no,,,,, P141,77,G5,P141_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL098C,FMC1,,"Mitochondrial matrix protein, required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p","mitochondrion organization, protein complex biogenesis",molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, organelle organization and biogenesis, response to chemical stimulus",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,6,2,no,,,,, P141,78,G6,P141_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL099W,SGA1,,"Intracellular sporulation-specific glucoamylase involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation","cellular carbohydrate metabolic process, sporulation resulting in formation of a cellular spore, generation of precursor metabolites and energy",hydrolase activity,"vacuole, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, sporulation, vacuole",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,5,2.9,no,,,,, P141,79,G7,P141_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL100W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the dubious ORF YIL100C-A",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,12,3.8,no,,,,, P141,80,G8,P141_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL101C,XBP1,,"Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate",response to stress,DNA binding,nucleus,"DNA binding, nucleus, response to stress, transcription regulator activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,12,4.5,no,,,,, P141,81,G9,P141_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL103W,DPH1,KIF48,"Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p",protein modification process,molecular_function,cytoplasm,"cytoplasm, molecular_function, protein modification process",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,2,0.8,no,,,,, P141,82,G10,P141_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL105C,SLM1,LIT2,"Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex","signaling process, cytoskeleton organization",lipid binding,"membrane fraction, mitochondrion, membrane, cytoplasm, plasma membrane","cytoplasm, cytoskeleton organization and biogenesis, lipid binding, mitochondrion, organelle organization and biogenesis, other, plasma membrane, signal transduction",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,230,7,3,no,,,,, P141,83,G11,P141_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL107C,PFK26,PFK-2;PFK2,"6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate; has negligible fructose-2,6-bisphosphatase activity; transcriptional regulation involves protein kinase A","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,12,4.8,no,,,,, P141,84,G12,P141_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL108W,,,Putative metalloprotease,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,8,3,no,,,,, P141,85,H1,P141_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL110W,HPM1,MNI1,AdoMet-dependent methyltransferase involved in a novel 3-methylhistidine modification of ribosomal protein Rpl3p; seven beta-strand MTase family member; null mutant exhibits a weak vacuolar protein sorting defect and caspofungin resistance,protein modification process,transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, response to chemical stimulus, transferase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,2,0.7,no,,,,, P141,86,H2,P141_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL112W,HOS4,,"Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate","meiosis, chromosome organization, cell cycle, protein modification process",molecular_function,"nucleus, chromosome","cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, protein modification process",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,12,4.2,no,,,,, P141,87,H3,P141_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P141,88,H4,P141_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL113W,SDP1,,"Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock",signaling process,"phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","cell wall organization and biogenesis, cytoplasm, hydrolase activity, nucleus, phosphoprotein phosphatase activity, signal transduction",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,6,1.9,no,,,,, P141,89,H5,P141_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL114C,POR2,YVDAC2,"Putative mitochondrial porin (voltage-dependent anion channel), related to Por1p but not required for mitochondrial membrane permeability or mitochondrial osmotic stability","transport, cellular homeostasis",transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,12,4.7,no,,,,, P141,90,H6,P141_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL116W,HIS5,,"Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts","cellular amino acid and derivative metabolic process, heterocycle metabolic process",transferase activity,other,"amino acid and derivative metabolic process, other, transferase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,7,3.7,no,,,,, P141,91,H7,P141_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL117C,PRM5,,"Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling",biological_process,molecular_function,membrane,"conjugation, membrane, molecular_function, response to chemical stimulus",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,6,2.8,no,,,,, P141,92,H8,P141_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL119C,RPI1,,Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation,"signaling process, vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",enzyme regulator activity,nucleus,"enzyme regulator activity, nucleus, signal transduction, vitamin metabolic process",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,20,6.5,no,,,,, P141,93,H9,P141_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL120W,QDR1,,"Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, ketoconazole, fluconazole, and barban","transport, response to chemical stimulus",transporter activity,"membrane, plasma membrane","plasma membrane, response to chemical stimulus, transport, transporter activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,10,5.6,no,,,,, P141,94,H10,P141_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL121W,QDR2,,"Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake","transport, response to chemical stimulus",transporter activity,"membrane, plasma membrane","membrane, plasma membrane, response to chemical stimulus, transport, transporter activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,6,2.6,no,,,,, P141,95,H11,P141_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL123W,SIM1,,"Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated",fungal-type cell wall organization,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,200,5,2.5,no,,,,, P141,96,H12,P141_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL124W,AYR1,1-acyl dihydroxyacetone phosphate reductase,"NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones",cellular lipid metabolic process,oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, lipid metabolic process, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,258,8,3.1,no,,,,, P142,1,A1,P142_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL125W,KGD1,OGD1,"Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA","cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",oxidoreductase activity,"mitochondrion, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, mitochondrion, other, oxidoreductase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,179,1,0.6,no,,,,, P142,2,A2,P142_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL128W,MET18,MMS19,"DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance","response to stress, transcription, cellular amino acid and derivative metabolic process, DNA metabolic process, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, amino acid and derivative metabolic process, nucleus, response to stress, transcription, transcription regulator activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,7,2.6,no,,,,, P142,3,A3,P142_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL130W,ASG1,,"Zinc cluster protein proposed to function as a transcriptional regulator involved in the stress response; null mutants have a respiratory deficiency, calcofluor white sensitivity and slightly increased cycloheximide resistance",biological_process,DNA binding,nucleus,"biological_process, molecular_function, nucleus",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,6,2.7,no,,,,, P142,4,A4,P142_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL132C,CSM2,,"Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, required for accurate chromosome segregation during meiosis","response to stress, meiosis, cell cycle, DNA metabolic process, chromosome segregation",molecular_function,"nucleus, cytoplasm","DNA metabolic process, cell cycle, cytoplasm, meiosis, molecular_function, nucleus, response to stress",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,10,3.1,no,,,,, P142,5,A5,P142_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL133C,RPL16A,rp22;YL15;L21A;L16A;RPL13,"N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p",translation,"RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, ribosome, structural molecule activity, translation",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,4,1.3,no,,,,, P142,6,A6,P142_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL134W,FLX1,,"Protein required for transport of flavin adenine dinucleotide (FAD), a synthesis product of riboflavin, across the mitochondrial membrane",transport,transporter activity,"mitochondrion, cytoplasm","mitochondrion, transport, transporter activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,6,2.2,no,,,,, P142,7,A7,P142_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL135C,VHS2,,"Cytoplasmic protein of unknown function; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; similar to Mlf3p",cell cycle,molecular_function,cytoplasm,"cell cycle, cytoplasm, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,3,1.7,no,,,,, P142,8,A8,P142_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL137C,TMA108,RBF108,Protein that associates with ribosomes; putative metalloprotease,biological_process,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, ribosome",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,14,4.9,no,,,,, P142,9,A9,P142_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL138C,TPM2,tropomyosin,"Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p","vacuole organization, transport, cell budding, mitochondrion organization, cytoskeleton organization, vesicle-mediated transport",protein binding,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding, site of polarized growth, transport, vesicle-mediated transport",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,6,2,no,,,,, P142,10,A10,P142_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL139C,REV7,,"Accessory subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair","response to stress, DNA metabolic process","transferase activity, nucleotidyltransferase activity","nucleus, chromosome, mitochondrion, cytoplasm","DNA metabolic process, mitochondrion, nucleotidyltransferase activity, other, response to stress, transferase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,8,3.9,no,,,,, P142,11,A11,P142_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL140W,AXL2,SRO4;BUD10,"Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate","cell budding, cytokinesis, cell cycle",molecular_function,"cell cortex, cytoskeleton, cellular bud, membrane, site of polarized growth, cytoplasm, plasma membrane","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, membrane, molecular_function, plasma membrane, site of polarized growth",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,0,0,no,,,,, P142,12,A12,P142_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL141W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,2,0.8,no,,,,, P142,13,B1,P142_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL145C,PAN6,,"Pantothenate synthase, also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC","cofactor metabolic process, cellular amino acid and derivative metabolic process",ligase activity,"nucleus, cytoplasm","cofactor metabolic process, cytoplasm, ligase activity, nucleus",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,6,2,no,,,,, P142,14,B2,P142_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL146C,ATG32,ECM37,"Mitochondrial-anchored transmembrane receptor that interacts with the autophagy adaptor protein, Atg11p, and is essential for mitophagy, the selective vacuolar degradation of mitochondria in response to starvation",fungal-type cell wall organization,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cell wall organization and biogenesis, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,8,3.4,no,,,,, P142,15,B3,P142_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL148W,RPL40A,L40A;UB11;UBI1;CEP52A,"Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes","translation, ribosome biogenesis, protein modification process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, other, protein modification process, ribosome, ribosome biogenesis, structural molecule activity, translation",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,12,5.1,no,,,,, P142,16,B4,P142_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL149C,MLP2,,"Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length","transport, cytoskeleton organization, transcription, cell cycle",other,"nucleus, cytoskeleton, microtubule organizing center, endomembrane system, mitochondrion, cytoplasm","endomembrane system, mitochondrion, nucleus, other, transcription, transport",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,6,2.2,no,,,,, P142,17,B5,P142_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL152W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,10,3.5,no,,,,, P142,18,B6,P142_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL153W,RRD1,YPA1,"Peptidyl-prolyl cis/trans-isomerase, activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; subunit of the Tap42p-Sit4p-Rrd1p complex","response to stress, cytoskeleton organization, cell cycle, DNA metabolic process","isomerase activity, enzyme regulator activity","nucleus, cytoplasm","DNA metabolic process, cell cycle, cytoplasm, cytoskeleton organization and biogenesis, enzyme regulator activity, isomerase activity, nucleus, organelle organization and biogenesis, other, response to stress",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,4,2.5,no,,,,, P142,19,B7,P142_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL155C,GUT2,,"Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner","cofactor metabolic process, cellular carbohydrate metabolic process",oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, carbohydrate metabolic process, cofactor metabolic process, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, vitamin metabolic process",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,18,5.7,no,,,,, P142,20,B8,P142_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL156W,UBP7,,Ubiquitin-specific protease that cleaves ubiquitin-protein fusions,protein modification process,"peptidase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, peptidase activity, protein modification process",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,12,4.5,no,,,,, P142,21,B9,P142_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL157C,COA1,FMP35,Mitochondrial inner membrane protein required for assembly of the cytochrome c oxidase complex (complex IV); interacts with complex IV assembly factor Shy1p during the early stages of assembly,"mitochondrion organization, protein complex biogenesis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, translation",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,9,4.1,no,,,,, P142,22,B10,P142_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL159W,BNR1,,"Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1","cytoskeleton organization, protein complex biogenesis",protein binding,"cellular bud, site of polarized growth","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding, response to stress, site of polarized growth",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,2,0.8,no,,,,, P142,23,B11,P142_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL160C,POT1,POX3;FOX3,"3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids",cellular lipid metabolic process,transferase activity,"peroxisome, cytoplasm","cytoplasm, lipid metabolic process, peroxisome, transferase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,22,7.9,no,,,,, P142,24,B12,P142_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL161W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; mRNA is enriched in Scp160p-associated mRNPs; YIL161W is a non-essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,3,1.7,no,,,,, P142,25,C1,P142_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL162W,SUC2,,"Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively",cellular carbohydrate metabolic process,hydrolase activity,"extracellular region, mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, extracellular region, hydrolase activity, mitochondrion",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,20,6.3,no,,,,, P142,26,C2,P142_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL163C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,8,3.2,no,,,,, P142,27,C3,P142_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL164C,NIT1,,"Nitrilase, member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene",biological_process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,14,5.4,no,,,,, P142,28,C4,P142_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL165C,,,"Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene",other,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,2,1.1,no,,,,, P142,29,C5,P142_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL166C,,,Putative protein with similarity to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene,transport,transporter activity,membrane,"membrane, transport, transporter activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,8,3.1,no,,,,, P142,30,C6,P142_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL167W,,,,,,,,,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,20,10.1,no,,,,, P142,31,C7,P142_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL168W,,,,,,,,,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,2,0.8,no,,,,, P142,32,C8,P142_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL170W,,,,,,,,,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,20,8.5,no,,,,, P142,33,C9,P142_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL173W,VTH1,,"Putative membrane glycoprotein with strong similarity to Vth2p and Pep1p/Vps10p, may be involved in vacuolar protein sorting","transport, vesicle-mediated transport",other,cytoplasm,"cytoplasm, other, transport, vesicle-mediated transport",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,14,5.9,no,,,,, P142,34,C10,P142_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR001C,SGN1,RBP29;RBP1,"Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation",RNA metabolic process,RNA binding,cytoplasm,"RNA binding, RNA metabolic process, cytoplasm",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,150,2,1.3,no,,,,, P142,35,C11,P142_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR002C,MPH1,,"Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype","response to stress, DNA metabolic process","DNA binding, helicase activity, hydrolase activity",nucleus,"DNA metabolic process, helicase activity, nucleus, response to stress",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,6,1.9,no,,,,, P142,36,C12,P142_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR003W,AIM21,,Protein of unknown function involved in mitochondrial migration along actin filament; may interact with ribosomes; GFP-fusion protein colocalizes with Sac1p to the actin cytoskeleton,other,molecular_function,"site of polarized growth, cytoskeleton, ribosome, cytoplasm","biological_process, cytoskeleton, molecular_function, ribosome",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,142,2,1.4,no,,,,, P142,37,D1,P142_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR005W,IST3,SNU17,"Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing","transport, RNA metabolic process",other,nucleus,"RNA metabolic process, nucleus, other, transport",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,3,1.7,no,,,,, P142,38,D2,P142_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR007W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YIR007W is a non-essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,4,1.4,no,,,,, P142,39,D3,P142_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR009W,MSL1,YIB9;YIB9w,"U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members",RNA metabolic process,RNA binding,nucleus,"RNA binding, RNA metabolic process, nucleus",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,6,2.3,no,,,,, P142,40,D4,P142_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR013C,GAT4,,Protein containing GATA family zinc finger motifs,transcription,DNA binding,nucleus,"DNA binding, nucleus, transcription, transcription regulator activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,0,0,no,,,,, P142,41,D5,P142_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR014W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,2,0.7,no,,,,, P142,42,D6,P142_D6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P142,43,D7,P142_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR016W,,,Putative protein of unknown function; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; overexpression causes a cell cycle delay or arrest; YIR016W is a non-essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,1,0.5,no,,,,, P142,44,D8,P142_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR306C,MCH5,,"Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,16,5.3,no,,,,, P142,45,D9,P142_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR309C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene NOP58",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,5,2.9,no,,,,, P142,46,D10,P142_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR325W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF FRT1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,9,5.1,no,,,,, P142,47,D11,P142_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR331C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; open reading frame overlaps the verified gene VMA4/YOR332W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,18,7,no,,,,, P142,48,D12,P142_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR333C,,SWF5,"Dubious open reading frame, unlikely to encode a functional protein; overlaps 5' end of MRS2 gene required for respiratory growth",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,251,4,1.6,no,,,,, P142,49,E1,P142_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR345C,,,"Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene REV1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,11,5.7,no,,,,, P142,50,E2,P142_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR366W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR365C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,15,7.6,no,,,,, P142,51,E3,P142_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR125C,CAT5,COQ7,Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation,cofactor metabolic process,oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,197,15,7.6,no,,,,, P142,52,E4,P142_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR128C,ADE2,,"Phosphoribosylaminoimidazole carboxylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine","heterocycle metabolic process, cellular aromatic compound metabolic process",lyase activity,cytoplasm,"aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, lyase activity, other",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,0,0,no,,,,, P142,53,E5,P142_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR141C,ARP8,,"Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes","response to stress, chromosome organization, DNA metabolic process","helicase activity, hydrolase activity","nucleus, chromosome","DNA metabolic process, helicase activity, hydrolase activity, nucleus, organelle organization and biogenesis, response to stress",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,282,16,5.7,no,,,,, P142,54,E6,P142_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR147W,MDM32,,"Mitochondrial inner membrane protein with similarity to Mdm31p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34","mitochondrion organization, cellular homeostasis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cellular homeostasis, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,26,7.7,no,,,,, P142,55,E7,P142_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR150W,MRPL23,YmL23,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,175,22,12.6,no,,,,, P142,56,E8,P142_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR187W,TUF1,tufM,"Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans","mitochondrion organization, translation","RNA binding, hydrolase activity","mitochondrion, cytoplasm","cytoplasm, hydrolase activity, mitochondrion, translation, translation regulator activity",,,15_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,172,1,0.6,no,,,,, P142,57,E9,P142_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL194W,SNF3,,Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmembrane segments and a long C-terminal tail required for induction of hexose transporters; also senses fructose and mannose; similar to Rgt2p,"transport, meiosis, signaling process, cell cycle, response to chemical stimulus",signal transducer activity,"membrane, plasma membrane","cell cycle, meiosis, other, plasma membrane, response to chemical stimulus, signal transducer activity, signal transduction",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,16,5.8,no,,,,, P142,58,E10,P142_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR007W,TRP1,,"Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)","cellular amino acid and derivative metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",isomerase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, isomerase activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,3,1.4,no,,,,, P142,59,E11,P142_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR048C,,,"Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,18,5.6,no,,,,, P142,60,E12,P142_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR011C,AIM13,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria; null mutant displays reduced respiratory growth and reduced frequency of mitochondrial genome loss",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,8,3,no,,,,, P142,61,F1,P142_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR013W,IOC3,,"Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; has homology to Esc8p, which is involved in silencing",chromosome organization,"DNA binding, protein binding, hydrolase activity",nucleus,"nucleus, organelle organization and biogenesis, protein binding",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,12,7,no,,,,, P142,62,F2,P142_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL051W,COG5,COD4;API4,"Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","transport, vesicle-mediated transport",molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, molecular_function, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,22,10.4,no,,,,, P142,63,F3,P142_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL052W,COX5A,,"Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,2,0.8,no,,,,, P142,64,F4,P142_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL056W,OCA2,,Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,0,0,no,,,,, P142,65,F5,P142_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL065W,AQR1,,"Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids","transport, response to chemical stimulus",transporter activity,"membrane, plasma membrane","plasma membrane, response to chemical stimulus, transport, transporter activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,4,1.7,no,,,,, P142,66,F6,P142_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL066W,SUN4,SCW3,"Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family",mitochondrion organization,hydrolase activity,"cell wall, mitochondrion, cytoplasm","cell wall, cytoplasm, hydrolase activity, mitochondrion, organelle organization and biogenesis",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,6,2.8,no,,,,, P142,67,F7,P142_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL067W,RPL9B,rp24;YL11;L9B;L8B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,4,1.2,no,,,,, P142,68,F8,P142_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL068C,FKH2,,Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase,"transcription, chromosome organization, pseudohyphal growth, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, RNA metabolic process, cell cycle, nucleus, pseudohyphal growth, transcription, transcription regulator activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,6,1.9,no,,,,, P142,69,F9,P142_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL070W,TOM7,YOK22;MOM7,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex,"transport, mitochondrion organization, cellular membrane organization",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,1,0.4,no,,,,, P142,70,F10,P142_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL071W,LAT1,PDA2;ODP2,"Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA",cofactor metabolic process,transferase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, transferase activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,4,2.3,no,,,,, P142,71,F11,P142_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL072W,RNH201,Rnh2A;RNH35,"Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; homolog of RNAse HI (the S. cerevisiae homolog of mammalian RNAse HII is RNH1); related to human AGS4 that causes Aicardi-Goutieres syndrome","DNA metabolic process, RNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, other",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,4,2.3,no,,,,, P142,72,F12,P142_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL073W,MSK1,,"Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria and for aminoacylation of mitochondrially encoded tRNA(Lys)","transport, mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,2,1.2,no,,,,, P142,73,G1,P142_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL074C,MLF3,YMK1,"Serine-rich protein of unknown function, predicted to be palmitoylated; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide",response to chemical stimulus,molecular_function,cytoplasm,"cytoplasm, molecular_function, response to chemical stimulus",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,6,1.8,no,,,,, P142,74,G2,P142_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL076W,MKS1,LYS80,Pleiotropic negative transcriptional regulator involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling,"transcription, RNA metabolic process",molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, other, signal transduction, transcription",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,2,0.7,no,,,,, P142,75,G3,P142_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL078W,NIS1,JIP1,Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network,cell cycle,molecular_function,"cellular bud, nucleus, site of polarized growth","cell cycle, cellular bud, molecular_function, nucleus, site of polarized growth",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,4,1.6,no,,,,, P142,76,G4,P142_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL079C,TPM1,tropomyosin,"Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently","vacuole organization, transport, cell budding, mitochondrion organization, cytoskeleton organization, vesicle-mediated transport, pseudohyphal growth",protein binding,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding, pseudohyphal growth, site of polarized growth, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,0,0,no,,,,, P142,77,G5,P142_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL080C,EOS1,,Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene,"response to chemical stimulus, protein modification process, response to stress, cellular carbohydrate metabolic process",molecular_function,"endomembrane system, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, protein modification process, response to chemical stimulus, response to stress",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,4,1.6,no,,,,, P142,78,G6,P142_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL082W,PMS1,,"ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL","response to stress, meiosis, cell cycle, DNA metabolic process","DNA binding, hydrolase activity","nucleus, cytoplasm","DNA binding, DNA metabolic process, cell cycle, cytoplasm, hydrolase activity, meiosis, nucleus, other, response to stress",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,164,6,3.7,no,,,,, P142,79,G7,P142_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL083W,SAL1,,"ADP/ATP transporter; member of the Ca2+-binding subfamily of mitochondrial carriers, with two EF-hand motifs; transport activity of either Sal1p or Pet9p is critical for viability; polymorphic in different S. cerevisiae strains",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, transport, transporter activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,0,0,no,,,,, P142,80,G8,P142_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL085W,MKT1,,"Protein that forms a complex with Pbp1p that may mediate posttranscriptional regulation of HO; involved in propagation of M2 dsRNA satellite of L-A virus; allelic variation affects mitochondrial genome stability, drug resistance, and more","response to stress, translation",hydrolase activity,cytoplasm,"cytoplasm, hydrolase activity, other, response to stress, translation",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,6,1.9,no,,,,, P142,81,G9,P142_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL087W,TCB2,,Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from the cell surface to intracellular vesicles near vacuole; contains 3 calcium and lipid binding domains; mRNA is targeted to the bud,biological_process,molecular_function,cellular bud,"biological_process, cellular bud, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,12,4.4,no,,,,, P142,82,G10,P142_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL090W,RHO2,,"Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly","fungal-type cell wall organization, signaling process, cytoskeleton organization","signal transducer activity, hydrolase activity",membrane fraction,"anatomical structure morphogenesis, cell wall organization and biogenesis, cytoskeleton organization and biogenesis, hydrolase activity, organelle organization and biogenesis, other, signal transducer activity, signal transduction",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,6,2.1,no,,,,, P142,83,G11,P142_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL091W,NST1,,"Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the splicing factor Msl1p and also displays genetic interaction with MSL1",response to stress,molecular_function,cytoplasm,"cytoplasm, molecular_function, response to stress",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,8,2.6,no,,,,, P142,84,G12,P142_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL093W,YPT53,,"Rab family GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis","transport, vesicle-mediated transport, cellular membrane organization",hydrolase activity,cytoplasm,"cytoplasm, hydrolase activity, membrane organization and biogenesis, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,10,4,no,,,,, P142,85,H1,P142_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL095C,,,Putative protein of unknown function predicted to contain a transmembrane domain; YNL095C is not an essential gene,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,0,0,no,,,,, P142,86,H2,P142_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL097C,PHO23,,"Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1) and its isoform ING3","chromosome organization, transcription, protein modification process, RNA metabolic process",protein binding,"nucleus, chromosome","hydrolase activity, nucleus, organelle organization and biogenesis, protein binding, protein modification process",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,2,0.7,no,,,,, P142,87,H3,P142_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P142,88,H4,P142_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL099C,OCA1,,"Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA","response to stress, response to chemical stimulus","phosphoprotein phosphatase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, phosphoprotein phosphatase activity, response to chemical stimulus, response to stress",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,14,5.8,no,,,,, P142,89,H5,P142_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL100W,AIM37,,Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays reduced respiratory growth and reduced frequency of mitochondrial genome loss,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,2,1.1,no,,,,, P142,90,H6,P142_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL104C,LEU4,,Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway,cellular amino acid and derivative metabolic process,transferase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, transferase activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,6,3.1,no,,,,, P142,91,H7,P142_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL105W,RRT16,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene INP52; identified in a screen for mutants with decreased levels of rDNA transcription",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,6,2.2,no,,,,, P142,92,H8,P142_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL106C,INP52,SJL2,"Polyphosphatidylinositol phosphatase, dephosphorylates a number of phosphatidylinositols (PIs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain",cellular lipid metabolic process,hydrolase activity,"cell cortex, site of polarized growth, membrane fraction, cytoskeleton, cytoplasm","cell cortex, cytoplasm, cytoskeleton, hydrolase activity, lipid metabolic process, membrane fraction",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,1,0.5,no,,,,, P142,93,H9,P142_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL107W,YAF9,,"Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain","response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",molecular_function,"nucleus, chromosome, cytoplasm","DNA metabolic process, RNA metabolic process, cytoplasm, molecular_function, nucleus, organelle organization and biogenesis, response to stress, transcription",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,2,0.8,no,,,,, P142,94,H10,P142_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL115C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL115C is not an essential gene,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,4,1.5,no,,,,, P142,95,H11,P142_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL119W,NCS2,TUC2,Protein required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae,"pseudohyphal growth, protein modification process, RNA metabolic process",molecular_function,cytoplasm,"cytoplasm, molecular_function, other, protein modification process, pseudohyphal growth, ribosome biogenesis",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,4,2.2,no,,,,, P142,96,H12,P142_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL120C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; deletion enhances replication of Brome mosaic virus in S. cerevisiae, but likely due to effects on the overlapping gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,4,2.2,no,,,,, P143,1,A1,P143_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL121C,TOM70,OMP1;MOM72;MAS70,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins,"transport, mitochondrion organization, cellular membrane organization",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,329,0,0,no,,,,, P143,2,A2,P143_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL125C,ESBP6,MCH3,"Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane",transport,transporter activity,"membrane, mitochondrion, cytoplasm","membrane, mitochondrion, transport, transporter activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,0,0,no,,,,, P143,3,A3,P143_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL130C,CPT1,,"Cholinephosphotransferase, required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription","cellular amino acid and derivative metabolic process, cellular lipid metabolic process",transferase activity,"membrane fraction, mitochondrion, membrane, mitochondrial envelope, Golgi apparatus, cytoplasm","endoplasmic reticulum, lipid metabolic process, transferase activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,4,1.2,no,,,,, P143,4,A4,P143_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR189W,RPS9B,rp21;YS11;S9B;S13;SUP46;RPS13A,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,2,0.7,no,,,,, P143,5,A5,P143_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR095C,OCA4,,"Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,,,,no,,,,, P143,6,A6,P143_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR102W-A,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,4,1.4,no,,,,, P143,7,A7,P143_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL133C-A,RPL41B,YL41;L47B;L41B;YDL134C-A;RPL47B,"Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Ap and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,12,4.3,no,,,,, P143,8,A8,P143_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR058C,TGL2,,Triacylglycerol lipase that is localized to the mitochondria; has lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli,cellular lipid metabolic process,hydrolase activity,"mitochondrion, cytoplasm","cellular_component, hydrolase activity, lipid metabolic process",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,2,1,no,,,,, P143,9,A9,P143_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR174W,HMO1,HSM2,"Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase","response to stress, chromosome organization, transcription, RNA metabolic process",DNA binding,"nucleus, nucleolus, chromosome, cytoplasm","DNA binding, RNA metabolic process, chromosome, cytoplasm, nucleolus, nucleus, other, transcription, transcription regulator activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,17,9.4,no,,,,, P143,10,A10,P143_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR202C,RAV2,,"Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme","cellular homeostasis, protein complex biogenesis",molecular_function,cytoplasm,"cellular homeostasis, cytoplasm, molecular_function, other",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,4,1.2,no,,,,, P143,11,A11,P143_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR205W,MSC2,,"Member of the cation diffusion facilitator family, localizes to the endoplasmic reticulum and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids","transport, cellular homeostasis",transporter activity,"membrane, endoplasmic reticulum, cytoplasm","cellular homeostasis, endoplasmic reticulum, membrane, transport, transporter activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,16,7.5,no,,,,, P143,12,A12,P143_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR445C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,12,4.9,no,,,,, P143,13,B1,P143_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR537C,,,"Dubious open reading frame unlikely to encode a protein, almost completely overlaps verified ORF PAD1/YDR538W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,8,4.3,no,,,,, P143,14,B2,P143_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR039C,,,Putative protein of unknown function; may be involved in response to high salt and changes in carbon source; deletion mutant has decreased spore survival in Drosophila feces,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,4,1.8,no,,,,, P143,15,B3,P143_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL219C,MDM34,MMM2,Mitochondrial component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth,"transport, mitochondrion organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,2,0.9,no,,,,, P143,16,B4,P143_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR028W,MSP1,YTA4,Mitochondrial protein involved in sorting of proteins in the mitochondria; putative membrane-spanning ATPase,"transport, mitochondrion organization",hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,14,4.7,no,,,,, P143,17,B5,P143_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR032W,GSC2,FKS2,"Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p)","cellular carbohydrate metabolic process, sporulation resulting in formation of a cellular spore, cellular component morphogenesis",transferase activity,"cell cortex, membrane fraction, cytoskeleton, membrane, cytoplasm, plasma membrane","carbohydrate metabolic process, cell cortex, cell wall organization and biogenesis, cytoplasm, cytoskeleton, membrane, membrane fraction, plasma membrane, sporulation, transferase activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,6,3.5,no,,,,, P143,18,B6,P143_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR038W,ORM1,,"Evolutionarily conserved protein, similar to Orm2p, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control","response to stress, cellular lipid metabolic process, response to chemical stimulus",molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, response to chemical stimulus, response to stress",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,3,1.6,no,,,,, P143,19,B7,P143_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR040W,KSS1,,Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains,"signaling process, transcription, response to chemical stimulus, protein modification process, conjugation","transferase activity, protein kinase activity, signal transducer activity, protein binding",nucleus,"conjugation, nucleus, other, protein binding, protein kinase activity, protein modification process, response to chemical stimulus, signal transducer activity, signal transduction, transcription, transferase activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,4,1.7,no,,,,, P143,20,B8,P143_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR050C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,5,2.6,no,,,,, P143,21,B9,P143_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR053C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,5,2.7,no,,,,, P143,22,B10,P143_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR063C,SPT4,,"Protein involved in the regulating Pol I and Pol II transcription, pre-mRNA processing, kinetochore function, and gene silencing; forms a complex with Spt5p","response to stress, chromosome organization, transcription, DNA metabolic process, chromosome segregation, RNA metabolic process",transcription regulator activity,"nucleus, chromosome","RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, other, transcription, transcription regulator activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,16,5.7,no,,,,, P143,23,B11,P143_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR086C,PIL1,,"Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria","transport, protein complex biogenesis, response to stress, vesicle-mediated transport, cellular membrane organization",enzyme regulator activity,"cell cortex, membrane fraction, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cell cortex, cytoplasm, enzyme regulator activity, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, other, response to stress, transport, vesicle-mediated transport",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,4,1.8,no,,,,, P143,24,B12,P143_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR089W,NNF2,,"Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation",biological_process,molecular_function,membrane fraction,"membrane fraction, molecular_function, other",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,4,1.5,no,,,,, P143,25,C1,P143_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR092W,DBF2,,Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis,"protein modification process, cellular homeostasis","transferase activity, protein kinase activity","cytoskeleton, microtubule organizing center, cellular bud, site of polarized growth, cytoplasm","cellular bud, cytoplasm, cytoskeleton, microtubule organizing center, organelle organization and biogenesis, protein kinase activity, protein modification process, site of polarized growth, transferase activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,12,7,no,,,,, P143,26,C2,P143_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR093W,,,Putative protein of unconfirmed function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus,biological_process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,3,1.7,no,,,,, P143,27,C3,P143_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR106C,VOA1,,"Endoplasmic reticulum protein that functions, together with other assembly factors, in assembly of the V0 sector of the vacuolar ATPase (V-ATPase); null mutation enhances the V-ATPase deficiency of a vma21 mutant impaired in ER retrieval",protein complex biogenesis,molecular_function,"membrane, endomembrane system, vacuole, endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,1,0.6,no,,,,, P143,28,C4,P143_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR110W,CLD1,,Mitochondrial cardiolipin-specific phospholipase; functions upstream of Taz1p to generate monolyso-cardiolipin; transcription increases upon genotoxic stress; involved in restricting Ty1 transposition; has homology to mammalian CGI-58,cellular lipid metabolic process,hydrolase activity,"mitochondrion, cytoplasm","biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,10,3.1,no,,,,, P143,29,C5,P143_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR117C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,4,1.4,no,,,,, P143,30,C6,P143_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR238C,KEL2,,"Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate","conjugation, cell cycle",molecular_function,"cellular bud, site of polarized growth","cell cycle, cellular bud, conjugation, molecular_function, site of polarized growth",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,14,4.3,no,,,,, P143,31,C7,P143_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR239C,PEX21,,Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex18p,"transport, peroxisome organization",protein binding,"peroxisome, cytoplasm","cytoplasm, organelle organization and biogenesis, other, peroxisome, protein binding, transport",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,1,0.6,no,,,,, P143,32,C8,P143_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR248W,SOL4,,6-phosphogluconolactonase with similarity to Sol3p,"cofactor metabolic process, cellular carbohydrate metabolic process",hydrolase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cofactor metabolic process, cytoplasm, hydrolase activity, nucleus, vitamin metabolic process",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,6,1.8,no,,,,, P143,33,C9,P143_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR250C,,,Putative RNA binding protein; localizes to stress granules induced by glucose deprivation; interacts with Rbg1p in a two-hybrid,biological_process,RNA binding,cytoplasm,"RNA binding, biological_process, cytoplasm",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,1,0.5,no,,,,, P143,34,C10,P143_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL129C,TRK1,,"Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation",cellular homeostasis,transporter activity,membrane,"cellular homeostasis, membrane, transporter activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,8,4.3,no,,,,, P143,35,C11,P143_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL132W,,,Putative protein of unknown function; localizes to the membrane fraction; possible Zap1p-regulated target gene induced by zinc deficiency; YJL132W is a non-essential gene,biological_process,molecular_function,membrane fraction,"biological_process, membrane fraction, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,3,1.7,no,,,,, P143,36,C12,P143_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL136C,RPS21B,YS25;S26B;S21B,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,16,5.3,no,,,,, P143,37,D1,P143_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL137C,GLG2,,"Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,28,15.9,no,,,,, P143,38,D2,P143_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL139C,YUR1,,"Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; located in the Golgi apparatus","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cell wall organization and biogenesis, protein modification process, transferase activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,14,6.8,no,,,,, P143,39,D3,P143_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL140W,RPB4,B32;CTF15,RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; involved in recruitment of 3'-end processing factors to transcribing RNA polymerase II complex and in export of mRNA to cytoplasm under stress conditions,"transport, transcription, protein complex biogenesis, response to stress, RNA metabolic process","RNA binding, DNA binding","nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleotidyltransferase activity, nucleus, transcription, transferase activity, transport",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,76,38.4,no,,,,, P143,40,D4,P143_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL141C,YAK1,,Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal,protein modification process,"transferase activity, protein kinase activity","nucleus, cytoplasm","cytoplasm, nucleus, protein kinase activity, protein modification process",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,21,9.5,no,,,,, P143,41,D5,P143_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL151C,SNA3,,"Integral membrane protein localized to vacuolar intralumenal vesicles, computational analysis of large-scale protein-protein interaction data suggests a possible role in either cell wall synthesis or protein-vacuolar targeting",biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,9,5.3,no,,,,, P143,42,D6,P143_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL160C,,,"Putative protein of unknown function; member of the PIR (proteins with internal repeats) family of cell wall proteins; non-essential gene that is required for sporulation; mRNA is weakly cell cycle regulated, peaking in mitosis",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,16,5.4,no,,,,, P143,43,D7,P143_D7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P143,44,D8,P143_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL161W,FMP33,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,19,9.5,no,,,,, P143,45,D9,P143_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL163C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,36,11.2,no,,,,, P143,46,D10,P143_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL165C,HAL5,,"Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters",cellular homeostasis,"transferase activity, protein kinase activity",cellular_component,"cellular homeostasis, cellular_component, protein kinase activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,12,5.7,no,,,,, P143,47,D11,P143_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL172W,CPS1,,Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions,cellular protein catabolic process,"peptidase activity, hydrolase activity","vacuole, cytoplasm","cytoplasm, hydrolase activity, other, peptidase activity, vacuole",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,24,8.6,no,,,,, P143,48,D12,P143_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL175W,,,"Dubious open reading frame unlikely to encode a functional protein; deletion confers resistance to cisplatin, hypersensitivity to 5-fluorouracil, and growth defect at high pH with high calcium; overlaps gene for SWI3 transcription factor",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,146,12,8.2,no,,,,, P143,49,E1,P143_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL177W,RPL17B,YL17;L20B;L17B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,76,28.1,no,,,,, P143,50,E2,P143_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL189W,RPL39,YL40;L46;L39;SPB2;RPL46;PUB2,"Protein component of the large (60S) ribosomal subunit, has similarity to rat L39 ribosomal protein; required for ribosome biogenesis; loss of both Rpl31p and Rpl39p confers lethality; also exhibits genetic interactions with SIS1 and PAB1",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,17,9.2,no,,,,, P143,51,E3,P143_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL191W,RPS14B,rp59B;S14B;CRY2,"Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Ap and similar to E. coli S11 and rat S14 ribosomal proteins","translation, ribosome biogenesis, RNA metabolic process","RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, nucleolus, nucleus, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,14,6.6,no,,,,, P143,52,E4,P143_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL196C,ELO1,,"Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids",cellular lipid metabolic process,transferase activity,membrane,"lipid metabolic process, membrane, transferase activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,13,5.4,no,,,,, P143,53,E5,P143_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL200C,ACO2,,"Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol",biological_process,lyase activity,"mitochondrion, cytoplasm","biological_process, lyase activity, mitochondrion",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,17,8,no,,,,, P143,54,E6,P143_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL206C,,,"Putative protein of unknown function; similar to transcriptional regulators from the Zn[2]-Cys[6] binuclear cluster protein family; mRNA is weakly cell cycle regulated, peaking in S phase; induced rapidly upon MMS treatment",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,13,7.5,no,,,,, P143,55,E7,P143_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL213W,,,"Protein of unknown function that may interact with ribosomes; periodically expressed during the yeast metabolic cycle; phosphorylated in vitro by the mitotic exit network (MEN) kinase complex, Dbf2p/Mob1p",biological_process,molecular_function,"ribosome, cytoplasm","biological_process, molecular_function, ribosome",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,22,9,no,,,,, P143,56,E8,P143_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL096W-A,CWP2,YKL097W-A;LPR1,"Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored",fungal-type cell wall organization,structural molecule activity,cell wall,"cell wall, cell wall organization and biogenesis, other, structural molecule activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,21,10,no,,,,, P143,57,E9,P143_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL115C,,,"Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene PRR1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,2,0.7,no,,,,, P143,58,E10,P143_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL139W,CTK1,,"Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity","translation, transcription, protein modification process, RNA metabolic process","transferase activity, protein kinase activity","nucleus, nucleolus","RNA metabolic process, nucleus, other, protein kinase activity, protein modification process, transcription, transferase activity, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,23,10.7,no,,,,, P143,59,E11,P143_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL194C,MST1,,Mitochondrial threonyl-tRNA synthetase,"mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,22,6.7,no,,,,, P143,60,E12,P143_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL201C,MNN4,YKL200C,"Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases","response to stress, cellular carbohydrate metabolic process, protein modification process",molecular_function,membrane,"membrane, molecular_function, protein modification process, response to stress",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,5,2.7,no,,,,, P143,61,F1,P143_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL202W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,4,2.1,no,,,,, P143,62,F2,P143_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL204W,EAP1,,"eIF4E-associated protein, competes with eIF4G for binding to eIF4E; inhibits cap-dependent translation; functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade",translation,protein binding,cytoplasm,"other, protein binding, response to chemical stimulus, translation",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,10,4.7,no,,,,, P143,63,F3,P143_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL215C,OXP1,,5-oxoprolinase; enzyme is ATP-dependent and functions as a dimer; similar to mouse Oplah gene; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm,"cofactor metabolic process, cellular amino acid and derivative metabolic process",hydrolase activity,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,6,2.8,no,,,,, P143,64,F4,P143_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL220C,FRE2,,"Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels",transport,oxidoreductase activity,"membrane, plasma membrane","oxidoreductase activity, plasma membrane, transport",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,19,9.3,no,,,,, P143,65,F5,P143_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR010C,TOF2,,Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase activity and biphasic release to promote rDNA repeat segregation; required for condensin recruitment to the replication fork barrier site,"transcription, chromosome segregation, chromosome organization, cell cycle, nucleus organization, RNA metabolic process",enzyme regulator activity,"nucleus, mitochondrion, nucleolus, cytoplasm","DNA metabolic process, RNA metabolic process, enzyme regulator activity, mitochondrion, nuclear organization and biogenesis, nucleolus, organelle organization and biogenesis, other, transcription",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,72,22.8,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P143,66,F6,P143_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR019C,IRS4,,"EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS","response to stress, fungal-type cell wall organization, signaling process, transcription, RNA metabolic process",molecular_function,"mitochondrion, cytoplasm","RNA metabolic process, cell wall organization and biogenesis, cytoplasm, mitochondrion, molecular_function, organelle organization and biogenesis, other, response to stress, signal transduction, transcription",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,6,3.2,no,,,,, P143,67,F7,P143_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR023W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,8,4.1,no,,,,, P143,68,F8,P143_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR027W,BCH2,FMP50,"Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane","transport, cellular carbohydrate metabolic process, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, mitochondrion, cytoplasm, Golgi apparatus","Golgi apparatus, carbohydrate metabolic process, cell wall organization and biogenesis, cytoplasm, cytoplasmic membrane-bounded vesicle, mitochondrion, molecular_function, transport, vesicle-mediated transport",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,2,1.2,no,,,,, P143,69,F9,P143_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR028W,SAP190,,"Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap185p","signaling process, cell cycle, RNA metabolic process",molecular_function,cytoplasm,"cell cycle, cytoplasm, molecular_function, other, signal transduction",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,8,2.5,no,,,,, P143,70,F10,P143_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR029C,SET3,,Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains,"transcription, protein modification process, meiosis, chromosome organization, cell cycle",protein binding,"nucleus, chromosome","cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, protein binding, protein modification process",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,10,3.2,no,,,,, P143,71,F11,P143_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR034W,DAL80,UGA43,"Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p","transcription, response to chemical stimulus, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, nucleus, other, transcription, transcription regulator activity",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,20,7.4,no,,,,, P143,72,F12,P143_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR036C,CAF4,,"WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission","mitochondrion organization, transcription, peroxisome organization, RNA metabolic process",molecular_function,"nucleus, mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, nucleus, organelle organization and biogenesis, protein binding, transcription",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,24,12.8,no,,,,, P143,73,G1,P143_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR039W,GAP1,,General amino acid permease; localization to the plasma membrane is regulated by nitrogen source,"transport, cellular amino acid and derivative metabolic process",transporter activity,"vacuole, cytoplasmic membrane-bounded vesicle, membrane, cytoplasm, plasma membrane","Golgi apparatus, amino acid and derivative metabolic process, cytoplasm, cytoplasmic membrane-bounded vesicle, membrane, plasma membrane, transport, transporter activity, vacuole",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,16,7.1,no,,,,, P143,74,G2,P143_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR040C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YKR041W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,30,9.8,no,,,,, P143,75,G3,P143_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR041W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,17,9.9,no,,,,, P143,76,G4,P143_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR046C,PET10,,Protein of unknown function that co-purifies with lipid particles; expression pattern suggests a role in respiratory growth; computational analysis of large-scale protein-protein interaction data suggests a role in ATP/ADP exchange,"generation of precursor metabolites and energy, cellular respiration",molecular_function,cytoplasm,"cellular respiration, cytoplasm, generation of precursor metabolites and energy, molecular_function",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,223,30,13.5,no,,,,, P143,77,G5,P143_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR053C,YSR3,LBP2,"Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p",cellular lipid metabolic process,hydrolase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, hydrolase activity, lipid metabolic process",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,28,13,no,,,,, P143,78,G6,P143_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML035C,AMD1,AMD3,"AMP deaminase, tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; may be involved in regulation of intracellular adenine nucleotide pools",heterocycle metabolic process,hydrolase activity,cytoplasm,"cytoplasm, hydrolase activity, other",,,00_14,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,56,17.9,no,,,,, P143,79,G7,P143_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAR002C-A,ERP1,,"Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles","transport, vesicle-mediated transport",molecular_function,"cytoplasmic membrane-bounded vesicle, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, mitochondrion, molecular_function, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,16,7.1,no,,,,, P143,80,G8,P143_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR083W,TEC1,ROC1,"Transcription factor required for full Ty1 expression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member","pseudohyphal growth, transcription, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"RNA metabolic process, nucleus, other, pseudohyphal growth, transcription, transcription regulator activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,1,0.4,no,,,,, P143,81,G9,P143_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR084C-A,RPL19A,rpl5L;YL14;L23A;L19A,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,4,1.8,no,,,,, P143,82,G10,P143_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR090C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,0,0,no,,,,, P143,83,G11,P143_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR098W,MMS4,YBR100W;SLX2,"Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination","chromosome segregation, response to stress, meiosis, cell cycle, DNA metabolic process","transcription regulator activity, hydrolase activity, protein binding",nucleus,"DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, other, protein binding, response to stress, transcription regulator activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,14,4.3,no,,,,, P143,84,G12,P143_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR112C,CYC8,SSN6;CRT8,"General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+]","chromosome organization, transcription","transcription regulator activity, protein binding",nucleus,"nucleus, organelle organization and biogenesis, protein binding, transcription, transcription regulator activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,251,3,1.2,no,,,,, P143,85,H1,P143_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR125C,PTC4,GCT1,Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppressor of the synthetic lethality of a cnb1 mpk1 double deletion; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity,biological_process,"phosphoprotein phosphatase activity, hydrolase activity",cytoplasm,"biological_process, cytoplasm, hydrolase activity, phosphoprotein phosphatase activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,3,1.4,no,,,,, P143,86,H2,P143_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR131W,CCZ1,CVT16,"Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway","transport, response to stress, vesicle-mediated transport, cellular membrane organization",enzyme regulator activity,"membrane, cytoplasm","cytoplasm, enzyme regulator activity, membrane, membrane organization and biogenesis, organelle organization and biogenesis, other, response to stress, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,1,0.5,no,,,,, P143,87,H3,P143_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P143,88,H4,P143_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR150C,TBS1,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,DNA binding,"nucleus, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function, nucleus",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,373,0,0,no,,,,, P143,89,H5,P143_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR168W,PEX32,,"Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p",peroxisome organization,molecular_function,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, molecular_function, organelle organization and biogenesis, peroxisome",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,4,1.7,no,,,,, P143,90,H6,P143_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR169C,SSE2,,Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p,protein folding,enzyme regulator activity,cytoplasm,"cytoplasm, other, protein folding",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,6,2,no,,,,, P143,91,H7,P143_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR270C,BIT2,,"Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; similar to Bit61p",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,0,0,no,,,,, P143,92,H8,P143_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR272C,HSM3,,Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); involved in DNA mismatch repair during slow growth; weak similarity to Msh1p; related to human 19S subunit S5b,"response to stress, DNA metabolic process, protein complex biogenesis",molecular_function,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, molecular_function, response to stress",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,3,1.3,no,,,,, P143,93,H9,P143_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR275C,RIF1,,Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation,"chromosome organization, transcription, DNA metabolic process, RNA metabolic process","DNA binding, protein binding","nucleus, chromosome","DNA binding, DNA metabolic process, RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, protein binding, transcription",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,2,1.1,no,,,,, P143,94,H10,P143_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR276C,PPS1,,"Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle","signaling process, cell cycle, protein modification process","phosphoprotein phosphatase activity, hydrolase activity",cellular_component,"cell cycle, cellular_component, hydrolase activity, phosphoprotein phosphatase activity, protein modification process",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,2,1.1,no,,,,, P143,95,H11,P143_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR280C,SAF1,,F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1,cellular protein catabolic process,ligase activity,other,"ligase activity, other, protein catabolic process",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,8,2.5,no,,,,, P143,96,H12,P143_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR287W,,ZSP1,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER; YBR287W is not an essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,4,1.6,no,,,,, P144,1,A1,P144_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR288C,APM3,YKS6,Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway,"transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasm","cytoplasm, membrane, molecular_function, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,0,0,no,,,,, P144,2,A2,P144_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR289W,SNF5,TYE4;SWI10;HAF4,Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p,"response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",transcription regulator activity,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, response to stress, transcription, transcription regulator activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,4,1.9,no,,,,, P144,3,A3,P144_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR294W,SUL1,SFP2,"High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,5,2.9,no,,,,, P144,4,A4,P144_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR301W,PAU24,DAN3,"Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; member of the seripauperin multigene family encoded mainly in subtelomeric regions; expressed under anaerobic conditions, completely repressed during aerobic growth",biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,6,2.1,no,,,,, P144,5,A5,P144_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL026C-A,FRM2,YCLX08C,"Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis; expression induced in cells treated with the mycotoxin patulin; has similarity to bacterial nitroreductases",cellular lipid metabolic process,oxidoreductase activity,"nucleus, cytoplasm","cytoplasm, lipid metabolic process, nucleus, oxidoreductase activity, response to chemical stimulus",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,8,2.6,no,,,,, P144,6,A6,P144_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR028C-A,RIM1,,Single-stranded DNA-binding protein essential for mitochondrial genome maintenance; involved in mitochondrial DNA replication,"mitochondrion organization, DNA metabolic process",DNA binding,"mitochondrion, cytoplasm","DNA binding, DNA metabolic process, cytoplasm, mitochondrion, organelle organization and biogenesis",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,12,5.8,no,,,,, P144,7,A7,P144_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR030C,SYP1,YCR029C-A,Protein of unknown function that is involved in endocytic site formation; may regulate assembly and disassembly of the septin ring; colocalizes and interacts with septin subunits; potential role in actin cytoskeletal organization,cytoskeleton organization,molecular_function,"cellular bud, site of polarized growth","biological_process, cellular bud, molecular_function, other, site of polarized growth",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,28,8.9,no,,,,, P144,8,A8,P144_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR032W,BPH1,,"PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins, which are implicated in disease syndromes due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting","transport, fungal-type cell wall organization",molecular_function,"membrane fraction, mitochondrion, cytoplasm","cell wall organization and biogenesis, membrane fraction, mitochondrion, molecular_function, other, transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,19,9,no,,,,, P144,9,A9,P144_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR033W,SNT1,,"Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein","signaling process, transcription, protein modification process, response to stress, meiosis, chromosome organization, cell cycle",molecular_function,"nucleus, chromosome","cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, protein modification process",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,28,15.6,no,,,,, P144,10,A10,P144_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR046C,IMG1,,"Mitochondrial ribosomal protein of the large subunit, required for respiration and for maintenance of the mitochondrial genome","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,12,3.9,no,,,,, P144,11,A11,P144_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR047C,BUD23,,"Methyltransferase, methylates residue G1575 of 18S rRNA; required for rRNA processing and nuclear export of 40S ribosomal subunits independently of methylation activity; diploid mutant displays random budding pattern","transport, cytokinesis, ribosome biogenesis, cell cycle, RNA metabolic process",transferase activity,"nucleus, nucleolus, cytoplasm","RNA metabolic process, anatomical structure morphogenesis, cytokinesis, cytoplasm, nucleus, organelle organization and biogenesis, ribosome biogenesis, transferase activity, transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,11,5.5,no,,,,, P144,12,A12,P144_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR048W,ARE1,SAT2,"Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen",other,transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, transferase activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,23,12.1,no,,,,, P144,13,B1,P144_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR053W,THR4,,"Threonine synthase, conserved protein that catalyzes formation of threonine from O-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway","transport, vesicle-mediated transport, cellular amino acid and derivative metabolic process, cellular membrane organization",lyase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, lyase activity, membrane organization and biogenesis, nucleus, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,14,7.9,no,,,,, P144,14,B2,P144_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR060W,TAH1,,"HSP90 cofactor; interacts with Hsp82p, Pih1p, Rvb1 and Rvb2, contains a single TPR domain with at least two TPR motifs",protein folding,protein binding,"nucleus, cytoplasm","cytoplasm, nucleus, protein binding, protein folding",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,24,7.7,no,,,,, P144,15,B3,P144_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR061W,,YCR062W,Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; induced by treatment with 8-methoxypsoralen and UVA irradiation,other,molecular_function,cytoplasm,"cytoplasm, molecular_function, other",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,4,2.3,no,,,,, P144,16,B4,P144_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR067C,SED4,,"Integral endoplasmic reticulum membrane protein, functions as a positive regulator of Sar1p probably through inhibition of GTPase activation by Sec23p; binds Sec16p, participates in vesicle formation, similar to Sec12p","transport, vesicle organization, heterocycle metabolic process, vesicle-mediated transport, cellular membrane organization",molecular_function,"endomembrane system, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, transport, vesicle-mediated transport",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,20,6.9,no,,,,, P144,17,B5,P144_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR069W,CPR4,SCC3;YCR070W;CYP4,"Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway",biological_process,isomerase activity,membrane,"biological_process, isomerase activity, membrane",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,1,0.5,no,,,,, P144,18,B6,P144_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR073C,SSK22,,"MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; functionally redundant with, and homologous to, Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p","response to stress, signaling process, protein modification process","transferase activity, signal transducer activity, protein kinase activity",cellular_component,"DNA metabolic process, cellular_component, protein kinase activity, protein modification process, response to stress, signal transducer activity, signal transduction, transferase activity, transposition",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,7,4,no,,,,, P144,19,B7,P144_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR075C,ERS1,,"Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains",transport,transporter activity,"vacuole, cytoplasm","cytoplasm, transport, transporter activity, vacuole",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,6,2.3,no,,,,, P144,20,B8,P144_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR083W,TRX3,,"Mitochondrial thioredoxin, highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p","response to stress, response to chemical stimulus",oxidoreductase activity,"mitochondrion, cytoplasm","mitochondrion, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,6,3,no,,,,, P144,21,B9,P144_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR084C,TUP1,UMR7;SFL2;ROX4;FLK1;CYC9;CRT4;AMM1;AER2;AAR1,"General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes","chromosome organization, transcription",transcription regulator activity,nucleus,"nucleus, organelle organization and biogenesis, transcription, transcription regulator activity",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P144,22,B10,P144_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR088W,ABP1,,"Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization",cytoskeleton organization,protein binding,"cell cortex, site of polarized growth, cytoskeleton, cytoplasm","anatomical structure morphogenesis, cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,6,2.5,no,,,,, P144,23,B11,P144_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR089W,FIG2,,"Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating","conjugation, cellular component morphogenesis, response to chemical stimulus",molecular_function,cell wall,"anatomical structure morphogenesis, cell wall, conjugation, molecular_function, response to chemical stimulus",,,00_16,,,,DIC:cell structure;YFP:Rad52-YFP protein,,166,4,2.4,no,,,,, P144,24,B12,P144_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR191W,RPL21A,L21A;URP1,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,2,0.8,no,,,,, P144,25,C1,P144_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL035C,GRX1,,Hydroperoxide and superoxide-radical responsive heat-stable glutathione-dependent disulfide oxidoreductase with active site cysteine pair; protects cells from oxidative damage,"response to stress, cellular homeostasis, response to chemical stimulus, protein modification process","transferase activity, oxidoreductase activity","nucleus, cytoplasm","cellular homeostasis, cytoplasm, nucleus, oxidoreductase activity, response to chemical stimulus, response to stress, transferase activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,34,13.3,no,,,,, P144,26,C2,P144_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR071C,PAA1,,"Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication",chromosome organization,transferase activity,cytoplasm,"cytoplasm, organelle organization and biogenesis, transferase activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,6,2.2,no,,,,, P144,27,C3,P144_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR074W,TPS2,PFK3;HOG2,"Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway","response to stress, cellular carbohydrate metabolic process",hydrolase activity,"mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, hydrolase activity, mitochondrion, response to stress",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,14,4.5,no,,,,, P144,28,C4,P144_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER027C,GAL83,SPM1,"One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain","signaling process, protein modification process, protein complex biogenesis","transferase activity, protein kinase activity","nucleus, endomembrane system, cytoplasm","cytoplasm, endomembrane system, nucleus, other, protein kinase activity, protein modification process, signal transduction, transferase activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,32,11,no,,,,, P144,29,C5,P144_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER037W,PHM8,,"Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,4,1.8,no,,,,, P144,30,C6,P144_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR155W,CYS4,VMA41;STR4;NHS5,"Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; mutations in human ortholog cause homocystinuria",cellular amino acid and derivative metabolic process,lyase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, lyase activity, mitochondrion, response to chemical stimulus",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,4,2,no,,,,, P144,31,C7,P144_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR192C,HCR1,,Dual function protein involved in translation initiation as a substoichiometric component (eIF3j) of translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA,"translation, ribosome biogenesis, RNA metabolic process",RNA binding,cytoplasm,"RNA binding, RNA metabolic process, cytoplasm, organelle organization and biogenesis, ribosome biogenesis, translation, translation regulator activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,2,0.8,no,,,,, P144,32,C8,P144_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR237W,THI7,THI10,"Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia",transport,transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,16,6.6,no,,,,, P144,33,C9,P144_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR246W,ERF2,,"Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole","transport, protein modification process",transferase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein modification process, transferase activity, transport",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,10,4.3,no,,,,, P144,34,C10,P144_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR334C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps a stand-alone long terminal repeat sequence whose presence indicates a retrotransposition event occurred here",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,8,3.1,no,,,,, P144,35,C11,P144_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR346C,,,"Putative protein of unknown function found in mitochondria; expression is regulated by transcription factors involved in pleiotropic drug resistance, Pdr1p and Yrr1p; YLR346C is not an essential gene",biological_process,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, response to chemical stimulus",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,12,4.6,no,,,,, P144,36,C12,P144_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR358C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSC2/YLR357W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,6,3.2,no,,,,, P144,37,D1,P144_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR361C,DCR2,,"Phosphoesterase involved in downregulation of the unfolded protein response, at least in part via dephosphorylation of Ire1p; dosage-dependent positive regulator of the G1/S phase transition through control of the timing of START","response to stress, cell cycle, response to chemical stimulus, protein modification process","phosphoprotein phosphatase activity, hydrolase activity",cellular_component,"cell cycle, cellular_component, hydrolase activity, phosphoprotein phosphatase activity, protein modification process, response to chemical stimulus, response to stress, signal transduction",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,6,1.8,no,,,,, P144,38,D2,P144_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR370C,ARC18,,"Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches","mitochondrion organization, cytoskeleton organization",molecular_function,"cytoskeleton, mitochondrion, cytoplasm","cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, structural molecule activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,28,9.5,no,,,,, P144,39,D3,P144_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR382C,NAM2,LeuRS;mitochondrial leucyl-tRNA synthetase;MSL1,"Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance","mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process","RNA binding, ligase activity","mitochondrion, cytoplasm","RNA binding, RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,0,0,no,,,,, P144,40,D4,P144_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR394W,CST9,ZIP3,SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate,"meiosis, chromosome organization, cell cycle, DNA metabolic process, protein modification process",ligase activity,"nucleus, chromosome","cell cycle, chromosome, ligase activity, meiosis, nucleus, organelle organization and biogenesis, protein modification process",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,15,5.9,no,,,,, P144,41,D5,P144_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR406C,RPL31B,YL28;L34B;L31B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,1,0.5,no,,,,, P144,42,D6,P144_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML022W,APT1,,"Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis","heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, nucleus, other, transferase activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,26,8.3,no,,,,, P144,43,D7,P144_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML027W,YOX1,,"Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate","transcription, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, chromosome","DNA binding, RNA metabolic process, cell cycle, nucleus, transcription, transcription regulator activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,32,17.6,no,,,,, P144,44,D8,P144_D8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P144,45,D9,P144_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML036W,CGI121,,"Protein involved in telomere uncapping and elongation as component of the KEOPS protein complex with Bud32p, Kae1p, Pcc1p, and Gon7p; also shown to be a component of the EKC protein complex; homolog of human CGI-121","chromosome organization, transcription, DNA metabolic process, RNA metabolic process",molecular_function,other,"RNA metabolic process, molecular_function, organelle organization and biogenesis, other, transcription",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,18,9.9,no,,,,, P144,46,D10,P144_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML038C,YMD8,,"Putative nucleotide sugar transporter, has similarity to Vrg4p",transport,transporter activity,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, transport, transporter activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,3,1.7,no,,,,, P144,47,D11,P144_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML041C,VPS71,SWC6,"Nucleosome-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting","transport, chromosome organization",other,"nucleus, chromosome","nucleus, organelle organization and biogenesis, other, transport",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,42,20.6,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P144,48,D12,P144_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML042W,CAT2,YCAT,"Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes","cellular amino acid and derivative metabolic process, vitamin metabolic process",transferase activity,"peroxisome, mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, peroxisome, transferase activity, vitamin metabolic process",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,16,8.4,no,,,,, P144,49,E1,P144_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML047C,PRM6,,"Pheromone-regulated protein, predicted to have 2 transmembrane segments; regulated by Ste12p during mating",biological_process,molecular_function,membrane,"conjugation, membrane, molecular_function, response to chemical stimulus",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,30,16.2,no,,,,, P144,50,E2,P144_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML075C,HMG1,,"One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae","cofactor metabolic process, cellular lipid metabolic process",oxidoreductase activity,"nucleus, endomembrane system, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, mitochondrion, nucleus, oxidoreductase activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,4,1.9,no,,,,, P144,51,E3,P144_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML076C,WAR1,,"Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induce transcription of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively",response to chemical stimulus,other,"nucleus, mitochondrion, cytoplasm","DNA binding, mitochondrion, nucleus, response to chemical stimulus, transcription regulator activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,10,4.6,no,,,,, P144,52,E4,P144_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML086C,ALO1,,"D-Arabinono-1,4-lactone oxidase, catalyzes the final step in biosynthesis of dehydro-D-arabinono-1,4-lactone, which is protective against oxidative stress","response to stress, heterocycle metabolic process, response to chemical stimulus",oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,3,1.7,no,,,,, P144,53,E5,P144_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR048W,CSM3,,"Replication fork associated factor, required for stable replication fork pausing; component of the DNA replication checkpoint pathway; required for accurate chromosome segregation during meiosis","signaling process, chromosome segregation, response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, meiosis, molecular_function, nucleus, organelle organization and biogenesis",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,1,0.5,no,,,,, P144,54,E6,P144_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR135W-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,22,7,no,,,,, P144,55,E7,P144_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR137C,PSO2,SNM1,Nuclease required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation,"response to stress, DNA metabolic process","DNA binding, hydrolase activity",nucleus,"DNA binding, DNA metabolic process, hydrolase activity, nucleus, response to stress",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,8,4.2,no,,,,, P144,56,E8,P144_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR138W,CIN4,UGX1;GTP1,"GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl; regulated by the GTPase-activating protein, Cin2p, the human retinitis pigmentosa 2 (RP2) homolog",protein folding,other,cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,20,6.5,no,,,,, P144,57,E9,P144_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR139W,RIM11,MDS1;GSK3,Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta,"response to stress, sporulation resulting in formation of a cellular spore, protein modification process","transferase activity, protein kinase activity",cytoplasm,"cytoplasm, other, protein kinase activity, protein modification process, response to stress, sporulation, transferase activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,24,11.4,no,,,,, P144,58,E10,P144_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR160W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; mutant has enhanced sensitivity to overexpression of mutant huntingtin; YMR160W is not an essential gene,biological_process,molecular_function,"membrane, vacuole, cytoplasm","biological_process, cytoplasm, membrane, molecular_function, vacuole",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,2,0.9,no,,,,, P144,59,E11,P144_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR173W,DDR48,FSP,"DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS","response to stress, DNA metabolic process",hydrolase activity,cytoplasm,"DNA metabolic process, cytoplasm, hydrolase activity, response to stress",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,12,6.5,no,,,,, P144,60,E12,P144_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR198W,CIK1,,"Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p","transport, cytoskeleton organization, chromosome segregation, meiosis, conjugation, chromosome organization, cell cycle, nucleus organization","motor activity, hydrolase activity, protein binding","cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, conjugation, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, meiosis, microtubule organizing center, motor activity, nuclear organization and biogenesis, organelle organization and biogenesis",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,7,2.9,no,,,,, P144,61,F1,P144_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR298C-A,MBF1,SUF13,Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations,"transcription, RNA metabolic process","transcription regulator activity, protein binding","nucleus, mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, nucleus, protein binding, transcription, transcription regulator activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,6,1.9,no,,,,, P144,62,F2,P144_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR364W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR365C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,4,1.7,no,,,,, P144,63,F3,P144_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL148C,PPT2,,"Phosphopantetheine:protein transferase (PPTase), activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation",protein modification process,transferase activity,"mitochondrion, cytoplasm","mitochondrion, protein modification process, transferase activity",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,0,0,no,,,,, P144,64,F4,P144_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL183C,RTT10,,Cytoplasmic protein with a role in regulation of Ty1 transposition,biological_process,molecular_function,cytoplasm,"DNA metabolic process, cytoplasm, molecular_function, transposition",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,3,1.7,no,,,,, P144,65,F5,P144_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL183W-A,RTC6,GON5,"Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome; null mutation suppresses cdc13-1 temperature sensitivity","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,36,11.3,no,,,,, P144,66,F6,P144_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL189W,GUP2,,Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog,transport,transferase activity,membrane,"membrane, transferase activity, transport",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,2,1,no,,,,, P144,67,F7,P144_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL224C,MMT2,MFT2,Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p,cellular homeostasis,molecular_function,"membrane, mitochondrion, cytoplasm","cellular homeostasis, membrane, mitochondrion, molecular_function",,,00_11,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,16,6.2,no,,,,, P144,68,F8,P144_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR295C,COS6,,"Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins",biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,6,2,no,,,,, P144,69,F9,P144_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR132W-A,IGO2,,Protein required for initiation of G0 program; prevents degradation of nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway; phosphorylated by Rim15p; GFP protein localizes to the cytoplasm and nucleus; similar to Igo1p,RNA metabolic process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,252,6,2.4,no,,,,, P144,70,F10,P144_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL030C,SSM4,KIS3;DOA10,Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear envelope; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation,cellular protein catabolic process,ligase activity,"nucleus, membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, ligase activity, membrane, nucleus, protein catabolic process",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,2,0.7,no,,,,, P144,71,F11,P144_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL058W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,10,3.1,no,,,,, P144,72,F12,P144_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL092W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,2,1,no,,,,, P144,73,G1,P144_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR023W,DAL81,UGA35,Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, other, transcription, transcription regulator activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,1,0.5,no,,,,, P144,74,G2,P144_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR030C,DCG1,,"Protein of unknown function, expression is sensitive to nitrogen catabolite repression and regulated by Dal80p; contains transmembrane domain",other,molecular_function,cellular_component,"cellular_component, molecular_function, other",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,2,1.1,no,,,,, P144,75,G3,P144_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR032C,DAL3,,"Ureidoglycolate hydrolase, converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression sensitive to nitrogen catabolite repression",heterocycle metabolic process,hydrolase activity,membrane,"heterocycle metabolic process, hydrolase activity, membrane",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,3,1.6,no,,,,, P144,76,G4,P144_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR043C,,,,,,,,,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,6,2.1,no,,,,, P144,77,G5,P144_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR044C,,,,,,,,,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,2,0.6,no,,,,, P144,78,G6,P144_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR003C,,,Putative protein of unknown function; detected in highly purified mitochondria in high-throughput studies; predicted to be involved in ribosome biogenesis,biological_process,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, ribosome biogenesis",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,2,1.1,no,,,,, P144,79,G7,P144_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR055W,HIT1,,"Protein of unknown function, required for growth at high temperature",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,2,0.9,no,,,,, P144,80,G8,P144_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL053C-A,MDM35,,Mitochondrial intermembrane space protein; mutation affects mitochondrial distribution and morphology; contains twin cysteine-x9-cysteine motifs,"mitochondrion organization, protein complex biogenesis",molecular_function,"nucleus, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, mitochondrial envelope, mitochondrion, molecular_function, nucleus, organelle organization and biogenesis",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,28,12.7,no,,,,, P144,81,G9,P144_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR106W,,,Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superfamily of membrane proteins; coding sequence 98% identical to that of YCL073C,transport,transporter activity,membrane,"membrane, transport, transporter activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,1,0.5,no,,,,, P144,82,G10,P144_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR191W,SPG5,,Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,8,3.3,no,,,,, P144,83,G11,P144_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR322C,SNO4,HSP34,"Possible chaperone and cysteine protease, similar to bacterial Hsp31 and yeast Hsp31p, Hsp32p, and Hsp33p; DJ-1/ThiJ/PfpI superfamily member; predicted involvement in pyridoxine metabolism; induced by mild heat stress and copper deprivation",biological_process,"peptidase activity, protein binding, hydrolase activity",cellular_component,"cellular_component, hydrolase activity, peptidase activity, protein binding, vitamin metabolic process",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,44,13.3,no,,,,, P144,84,G12,P144_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL140C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene THO2/YNL139C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,14,7.6,no,,,,, P144,85,H1,P144_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL142W,MEP2,,Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation,"transport, pseudohyphal growth",transporter activity,"membrane, plasma membrane","other, plasma membrane, pseudohyphal growth, transport, transporter activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,2,0.9,no,,,,, P144,86,H2,P144_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL315C,ATP11,,"Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase","mitochondrion organization, protein complex biogenesis",protein binding,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, organelle organization and biogenesis, protein binding",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,6,2.6,no,,,,, P144,87,H3,P144_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P144,88,H4,P144_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL151W,GRE2,,"3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway",other,oxidoreductase activity,"nucleus, cytoplasm","cytoplasm, lipid metabolic process, nucleus, other, oxidoreductase activity, response to stress",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,6,3.1,no,,,,, P144,89,H5,P144_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL152W,FRE7,,Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels,transport,oxidoreductase activity,"membrane, plasma membrane","oxidoreductase activity, plasma membrane, transport",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,7,3.4,no,,,,, P144,90,H6,P144_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL155C,HPF1,,Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines,fungal-type cell wall organization,hydrolase activity,"cell wall, extracellular region","cell wall, cell wall organization and biogenesis, extracellular region, hydrolase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,2,1.1,no,,,,, P144,91,H7,P144_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR265W,RBL2,,"Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin; similar to mouse beta-tubulin cofactor A","protein folding, cytoskeleton organization",protein binding,cytoplasm,"cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding, protein folding",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,176,7,4,no,,,,, P144,92,H8,P144_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR266W,PNT1,,"Mitochondrial integral inner membrane protein involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p; deletion mutant sensitive to the anti-Pneumocystis carinii drug pentamidine","mitochondrion organization, cellular membrane organization",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,18,7.4,no,,,,, P144,93,H9,P144_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR267C,HRK1,,Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis,cellular homeostasis,"transferase activity, protein kinase activity",cytoplasm,"cellular homeostasis, cytoplasm, protein kinase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,4,1.8,no,,,,, P144,94,H10,P144_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR268C,,,Putative protein of unknown function; sporulation is abnormal in homozygous diploid; YOR268C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,10,3,no,,,,, P144,95,H11,P144_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR269W,PAC1,,"Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1",transport,protein binding,"nucleus, cytoskeleton, cytoplasm","cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, nucleus, organelle organization and biogenesis, protein binding, transport",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,16,7.6,no,,,,, P144,96,H12,P144_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR270C,VPH1,,"Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes","cellular homeostasis, protein complex biogenesis","transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, other, transporter activity, vacuole",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,8,4.2,no,,,,, P145,1,A1,P145_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR271C,FSF1,,"Putative protein, predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,34,10.7,no,,,,, P145,2,A2,P145_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR273C,TPO4,,"Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily",transport,transporter activity,"membrane, vacuole, plasma membrane, cytoplasm","cytoplasm, membrane, plasma membrane, transport, transporter activity, vacuole",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,3,1.4,no,,,,, P145,3,A3,P145_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR274W,MOD5,,"Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms",RNA metabolic process,transferase activity,"nucleus, nucleolus, mitochondrion, cytoplasm","RNA metabolic process, cytoplasm, mitochondrion, nucleolus, nucleus, transferase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,5,2.3,no,,,,, P145,4,A4,P145_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR275C,RIM20,,Protein involved in proteolytic activation of Rim101p in response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation,sporulation resulting in formation of a cellular spore,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, other, protein modification process, sporulation",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,24,8.2,no,,,,, P145,5,A5,P145_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR276W,CAF20,p20;CAP20;CAF2,"Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E",translation,translation regulator activity,other,"other, translation, translation regulator activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,7,3.9,no,,,,, P145,6,A6,P145_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR298C-A,MBF1,SUF13,Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations,"transcription, RNA metabolic process","transcription regulator activity, protein binding","nucleus, mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, nucleus, protein binding, transcription, transcription regulator activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,2,0.9,no,,,,, P145,7,A7,P145_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR302W,,,"CPA1 uORF, Arginine attenuator peptide, regulates translation of the CPA1 mRNA",translation,translation regulator activity,cytoplasm,"cytoplasm, translation, translation regulator activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,8,4.6,no,,,,, P145,8,A8,P145_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR303W,CPA1,,"Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader",cellular amino acid and derivative metabolic process,ligase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, ligase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,4,1.5,no,,,,, P145,9,A9,P145_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL004C,LSP1,,"Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways","transport, response to stress, vesicle-mediated transport, cellular membrane organization",enzyme regulator activity,"cell cortex, membrane fraction, mitochondrion, membrane, mitochondrial envelope, cytoplasm","cell cortex, cytoplasm, enzyme regulator activity, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, response to stress, transport, vesicle-mediated transport",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,5,2.4,no,,,,, P145,10,A10,P145_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL017C,IRC15,,"Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci","cytoskeleton organization, chromosome segregation, meiosis, chromosome organization, cell cycle, DNA metabolic process","transferase activity, protein binding","cytoskeleton, cytoplasm","DNA metabolic process, cell cycle, cytoplasm, meiosis, organelle organization and biogenesis, transferase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,48,15.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P145,11,A11,P145_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL027W,SMA1,,Protein of unknown function involved in the assembly of the prospore membrane during sporulation; interacts with Spo14p,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cellular membrane organization",molecular_function,membrane,"cell wall organization and biogenesis, cellular_component, molecular_function, sporulation",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,18,6.6,no,,,,, P145,12,A12,P145_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL034W,,,Putative protein of unknown function; YPL034W is not essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,8,3.6,no,,,,, P145,13,B1,P145_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL036W,PMA2,,"Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential",transport,"hydrolase activity, transporter activity","membrane fraction, mitochondrion, membrane, cytoplasm, plasma membrane","hydrolase activity, mitochondrion, other, plasma membrane, transport, transporter activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,331,0,0,no,,,,, P145,14,B2,P145_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL078C,ATP4,LPF7,"Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated","transport, heterocycle metabolic process","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,255,4,1.6,no,,,,, P145,15,B3,P145_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL137C,GIP3,,"Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments",chromosome segregation,"protein binding, enzyme regulator activity","ribosome, mitochondrion, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, enzyme regulator activity, mitochondrion, other, protein binding, ribosome",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,3,1.3,no,,,,, P145,16,B4,P145_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL102C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,6,2,no,,,,, P145,17,B5,P145_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL012W-A,,YFL013W-A,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene IES1/YFL013C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,8,4.2,no,,,,, P145,18,B6,P145_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL014W,HSP12,HOR5;GLP1,"Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways","response to stress, response to chemical stimulus",molecular_function,"nucleus, membrane, membrane fraction, plasma membrane, cytoplasm","cytoplasm, molecular_function, nucleus, other, plasma membrane, response to chemical stimulus, response to stress",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,10,5.1,no,,,,, P145,19,B7,P145_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL019C,,,Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,20,9.6,no,,,,, P145,20,B8,P145_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL042C,,YFL043C,Putative protein of unknown function; YFL042C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,32,9.8,no,,,,, P145,21,B9,P145_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR019W,FAB1,SVL7,"1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis",cellular lipid metabolic process,"transferase activity, lipid binding","membrane, vacuole, mitochondrion, cytoplasm","cytoplasm, lipid binding, lipid metabolic process, membrane, mitochondrion, transferase activity, vacuole",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,332,10,3,no,,,,, P145,22,B10,P145_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR024C-A,LSB3,YFR024C,"Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization",other,molecular_function,"cellular bud, site of polarized growth, mitochondrion, cytoplasm","cellular bud, cytoplasm, cytoskeleton organization and biogenesis, mitochondrion, molecular_function, organelle organization and biogenesis, site of polarized growth",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,3,1.1,no,,,,, P145,23,B11,P145_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR025C,HIS2,,"Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control","cellular amino acid and derivative metabolic process, heterocycle metabolic process",hydrolase activity,other,"amino acid and derivative metabolic process, hydrolase activity, other",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,30,11.7,no,,,,, P145,24,B12,P145_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFR030W,MET10,,"Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide",other,oxidoreductase activity,other,"cytoplasm, other, oxidoreductase activity, response to chemical stimulus",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,48,15.3,no,,,,, P145,25,C1,P145_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR146W,CRP1,,Protein that binds to cruciform DNA structures,biological_process,DNA binding,nucleus,"DNA binding, biological_process, nucleus",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,211,3,1.4,no,,,,, P145,26,C2,P145_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR171W,ATG7,APG11;APG7;CVT2,"Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation","transport, protein modification process, response to stress, cellular membrane organization",other,"mitochondrion, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrion, other, protein modification process, response to stress, transport",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,0,0,no,,,,, P145,27,C3,P145_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL042W,MHP1,,Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins,"fungal-type cell wall organization, cytoskeleton organization",structural molecule activity,cytoskeleton,"cell wall organization and biogenesis, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, structural molecule activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,17,7.3,no,,,,, P145,28,C4,P145_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL070C,,,"Putative protein of unknown function with similarity to AMP deaminases; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YJL070C is a non-essential gene",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,273,16,5.9,no,,,,, P145,29,C5,P145_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL078C,PRY3,,Protein of unknown function,biological_process,molecular_function,cell wall,"biological_process, cell wall, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,17,6.1,no,,,,, P145,30,C6,P145_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL094C,KHA1,,"Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies",transport,transporter activity,"membrane, mitochondrion, cytoplasm, Golgi apparatus","Golgi apparatus, mitochondrion, transport, transporter activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,14,6.3,no,,,,, P145,31,C7,P145_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL101C,GSH1,,"Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury","response to stress, cofactor metabolic process, cellular amino acid and derivative metabolic process, response to chemical stimulus",ligase activity,other,"cofactor metabolic process, ligase activity, other, response to chemical stimulus, response to stress",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,5,2.6,no,,,,, P145,32,C8,P145_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL105W,SET4,,"Protein of unknown function, contains a SET domain",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,4,2,no,,,,, P145,33,C9,P145_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL128C,PBS2,SSK4;SFS4;HOG4,"MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress; plays a role in regulating Ty1 transposition","transport, signaling process, cytoskeleton organization, protein modification process, response to stress","transferase activity, protein kinase activity, structural molecule activity, protein binding","cellular bud, site of polarized growth, cytoplasm","DNA metabolic process, cellular bud, cytoplasm, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding, protein kinase activity, protein modification process, response to stress, signal transduction, site of polarized growth, transferase activity, transport, transposition",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,32,12.2,no,,,,, P145,34,C10,P145_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR085C,MRPL20,YmL20,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, organelle organization and biogenesis, ribosome, structural molecule activity, translation",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,19,8.5,no,,,,, P145,35,C11,P145_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR094C,RPL40B,L40B;UB12;CEP52B;UBI2,"Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes","translation, ribosome biogenesis, protein modification process",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, protein modification process, ribosome, ribosome biogenesis, structural molecule activity, translation",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,17,8.2,no,,,,, P145,36,C12,P145_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR095W,MLP1,MPL1,"Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs","transport, transcription, chromosome organization, RNA metabolic process",other,"nucleus, cytoskeleton, microtubule organizing center, endomembrane system, cytoplasm","endomembrane system, nucleus, other, transcription, transport",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,38,12.4,no,,,,, P145,37,D1,P145_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR096W,,,"Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc domain",biological_process,molecular_function,"nucleus, ribosome, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus, ribosome",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,3,1.8,no,,,,, P145,38,D2,P145_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR102W,FLO10,,"Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation",other,other,cell wall,"cell wall, other",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,259,16,6.2,no,,,,, P145,39,D3,P145_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR110C,CCW12,,"Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor","fungal-type cell wall organization, conjugation, response to chemical stimulus",molecular_function,cell wall,"cell wall, cell wall organization and biogenesis, conjugation, molecular_function, response to chemical stimulus",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,162,12,7.4,no,,,,, P145,40,D4,P145_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR390W-A,CCW14,ICWP;YLR391W;SSR1;YLR391W-A,"Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall",fungal-type cell wall organization,structural molecule activity,"cell wall, mitochondrion, cytoplasm","cell wall, cell wall organization and biogenesis, mitochondrion, structural molecule activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,10,3.3,no,,,,, P145,41,D5,P145_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR439W,MRPL4,YmL40,Mitochondrial ribosomal protein of the large subunit,translation,structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,40,13.5,no,,,,, P145,42,D6,P145_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR442C,SIR3,STE8;MAR2;CMT1,"Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p","transcription, response to stress, chromosome organization, DNA metabolic process, RNA metabolic process","DNA binding, structural molecule activity, protein binding","nucleus, chromosome, mitochondrion, nucleolus, cytoplasm","DNA metabolic process, RNA metabolic process, chromosome, mitochondrion, nucleolus, nucleus, organelle organization and biogenesis, other, protein binding, response to stress, structural molecule activity, transcription",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,ND,ND,,no,,,,, P145,43,D7,P145_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR455W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO),biological_process,molecular_function,nucleus,"molecular_function, nucleus, response to chemical stimulus",,,00_15,,,rg notes: Replaced 11/08/00 by consortium and new one added at end,DIC:cell structure;YFP:Rad52-YFP protein,,330,16,4.8,no,,,,, P145,44,D8,P145_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML066C,SMA2,,Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation,"sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cellular membrane organization",molecular_function,"membrane, cytoplasm","cell wall organization and biogenesis, cytoplasm, membrane, molecular_function, sporulation",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,26,8.8,no,,,,, P145,45,D9,P145_D9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P145,46,D10,P145_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML115C,VAN1,LDB13;VRG8;VRG7,"Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, protein modification process, transferase activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,16,6.6,no,,,,, P145,47,D11,P145_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR037C,MSN2,,"Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression","response to stress, transcription, response to chemical stimulus, RNA metabolic process",DNA binding,"nucleus, cytoplasm","DNA binding, RNA metabolic process, cytoplasm, nucleus, other, response to chemical stimulus, response to stress, transcription, transcription regulator activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,13,5.4,no,,,,, P145,48,D12,P145_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR104C,YPK2,YKR2,Protein kinase with similarity to serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK,"protein modification process, protein complex biogenesis","transferase activity, protein kinase activity","nucleus, cytoplasm","cytoplasm, nucleus, protein kinase activity, protein modification process",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,30,10.2,no,,,,, P145,49,E1,P145_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR119W,ASI1,,Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals,cellular protein catabolic process,ligase activity,"nucleus, membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, ligase activity, membrane, nucleus, protein catabolic process",,,00_15,,,rg notes: Replaced 11/08/00 by consortium and new one added at end,DIC:cell structure;YFP:Rad52-YFP protein,,203,14,6.9,no,,,,, P145,50,E2,P145_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR052C,POP2,CAF1,"RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation","transcription, RNA metabolic process",hydrolase activity,"nucleus, site of polarized growth, cytoplasm","RNA metabolic process, cytoplasm, hydrolase activity, nucleus, transcription",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,2,1.2,no,,,,, P145,51,E3,P145_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR055C,HOL1,,Putative transporter in the major facilitator superfamily (DHA1 family) of multidrug resistance transporters; mutations in membrane-spanning domains permit cation and histidinol uptake,transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, plasma membrane, transport, transporter activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,2,1.1,no,,,,, P145,52,E4,P145_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR069C,BSC5,,"Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,8,2.5,no,,,,, P145,53,E5,P145_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL125W,TRM13,,2'-O-methyltransferase responsible for modification of tRNA at position 4; C-terminal domain has similarity to Rossmann-fold (RFM) superfamily of RNA methyltransferases,RNA metabolic process,transferase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, transferase activity",,,00_15,,,rg notes: Replaced 11/08/00 by consortium and new one added at end,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P145,54,E6,P145_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL147C,PEX11,PMP27;PMP24,Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxidation; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p,"cellular lipid metabolic process, peroxisome organization",molecular_function,"peroxisome, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, lipid metabolic process, membrane, molecular_function, organelle organization and biogenesis, peroxisome",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,24,10.3,no,,,,, P145,55,E7,P145_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR007C,REC8,SPO69,Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p,"chromosome segregation, meiosis, chromosome organization, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","cell cycle, chromosome, meiosis, nucleus, organelle organization and biogenesis, other",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,323,17,5.3,no,,,,, P145,56,E8,P145_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR008W,HAA1,,"Transcriptional activator involved in the transcription of TPO2, YRO2, and other genes putatively encoding membrane stress proteins; involved in adaptation to weak acid stress","transcription, response to chemical stimulus, protein complex biogenesis, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,2,0.9,no,,,,, P145,57,E9,P145_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR013C,,,Putative zinc finger protein; YPR013C is not an essential gene,biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,10,3.7,no,,,,, P145,58,E10,P145_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR022C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS,biological_process,DNA binding,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,12,5.3,no,,,,, P145,59,E11,P145_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR023C,EAF3,,"Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition","transcription, protein modification process, response to stress, chromosome organization, DNA metabolic process, RNA metabolic process","transferase activity, hydrolase activity","nucleus, chromosome","DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, protein modification process, response to stress, transcription, transferase activity, transposition",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,27,11.7,no,,,,, P145,60,E12,P145_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR024W,YME1,YTA11;OSD1,"Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover","mitochondrion organization, cellular protein catabolic process","peptidase activity, hydrolase activity","membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, peptidase activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,32,9.7,no,,,,, P145,61,F1,P145_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR026W,ATH1,,Acid trehalase required for utilization of extracellular trehalose,"response to stress, cellular carbohydrate metabolic process",hydrolase activity,"cell wall, vacuole, cytoplasm","carbohydrate metabolic process, cell wall, cytoplasm, hydrolase activity, other, response to stress, vacuole",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,8,4.5,no,,,,, P145,62,F2,P145_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR031W,NTO1,,Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3,"chromosome organization, protein modification process","transferase activity, protein binding","nucleus, cytoplasm","cytoplasm, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transferase activity",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,237,21,8.9,no,,,,, P145,63,F3,P145_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR037C,ERV2,,"Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER","protein folding, protein modification process",oxidoreductase activity,membrane fraction,"membrane fraction, oxidoreductase activity, protein folding, protein modification process",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,6,2.5,no,,,,, P145,64,F4,P145_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR043W,RPL43A,L43A,"Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,14,4.6,no,,,,, P145,65,F5,P145_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR050C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MAK3/YPR051W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,10,5.1,no,,,,, P145,66,F6,P145_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR064W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,2,1,no,,,,, P145,67,F7,P145_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR078C,,,Putative protein of unknown function; possible role in DNA metabolism and/or in genome stability; expression is heat-inducible,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_15,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,8,3.6,no,,,,, P145,68,F8,P145_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR081C,SPT7,GIT2,"Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex","protein modification process, protein complex biogenesis, conjugation, chromosome organization",structural molecule activity,"nucleus, mitochondrion, cytoplasm","conjugation, mitochondrion, nucleus, organelle organization and biogenesis, other, protein modification process, structural molecule activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,366,0,0,no,,,,, P145,69,F9,P145_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR084W,MIS1,,"Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase","cofactor metabolic process, cellular amino acid and derivative metabolic process, vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process","transferase activity, ligase activity, hydrolase activity, oxidoreductase activity","mitochondrion, cytoplasm","RNA metabolic process, aromatic compound metabolic process, cofactor metabolic process, heterocycle metabolic process, hydrolase activity, ligase activity, mitochondrion, other, oxidoreductase activity, protein modification process, ribosome biogenesis, translation, vitamin metabolic process",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,6,2.3,no,,,,, P145,70,F10,P145_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR085W,AAC3,ANC3,"Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Pet9p and Aac1p; has roles in maintenance of viability and in respiration","transport, cofactor metabolic process, heterocycle metabolic process, generation of precursor metabolites and energy, cellular respiration",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transporter activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,3,1.5,no,,,,, P145,71,F11,P145_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR089C-A,NHP6B,YBR090C-A,High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; homologous to mammalian HMGB1 and HMGB2,"chromosome organization, transcription, protein complex biogenesis, RNA metabolic process",DNA binding,nucleus,"RNA metabolic process, chromosome, nucleus, organelle organization and biogenesis, other, transcription",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,0,0,no,,,,, P145,72,F12,P145_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR092C,PHO3,phoC,"Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin","vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",hydrolase activity,other,"hydrolase activity, other, vitamin metabolic process",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,1,0.5,no,,,,, P145,73,G1,P145_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR093C,PHO5,phoE,Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2,response to stress,hydrolase activity,cell wall,"cell wall, hydrolase activity, other, response to stress",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,2,0.7,no,,,,, P145,74,G2,P145_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR094W,PBY1,,Putative tubulin tyrosine ligase associated with P-bodies,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,247,2,0.8,no,,,,, P145,75,G3,P145_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR095C,RXT2,RAF60,Subunit of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth,"conjugation, chromosome organization, transcription, protein modification process, RNA metabolic process",hydrolase activity,"nucleus, chromosome","RNA metabolic process, conjugation, hydrolase activity, nucleus, organelle organization and biogenesis, other, protein modification process, transcription",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,335,0,0,no,,,,, P145,76,G4,P145_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR096W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,2,1.2,no,,,,, P145,77,G5,P145_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR098W,MMS4,YBR100W;SLX2,"Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination","chromosome segregation, response to stress, meiosis, cell cycle, DNA metabolic process","transcription regulator activity, hydrolase activity, protein binding",nucleus,"DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, other, protein binding, response to stress, transcription regulator activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,3,1.7,no,,,,, P145,78,G6,P145_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR099C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene MMS4",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,4,1.4,no,,,,, P145,79,G7,P145_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR098W,MMS4,YBR100W;SLX2,"Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination","chromosome segregation, response to stress, meiosis, cell cycle, DNA metabolic process","transcription regulator activity, hydrolase activity, protein binding",nucleus,"DNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, other, protein binding, response to stress, transcription regulator activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,3,1,no,,,,, P145,80,G8,P145_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR101C,FES1,,"Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum",translation,enzyme regulator activity,"ribosome, cytoplasm","cytoplasm, other, ribosome, translation",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,8,3.8,no,,,,, P145,81,G9,P145_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR103W,SIF2,EMB1,"WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus","signaling process, transcription, protein modification process, response to stress, meiosis, chromosome organization, cell cycle, RNA metabolic process",molecular_function,"nucleus, chromosome","RNA metabolic process, cell cycle, hydrolase activity, meiosis, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription, transcription regulator activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,3,1.6,no,,,,, P145,82,G10,P145_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR104W,YMC2,,"Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc1p",transport,transporter activity,"mitochondrion, cytoplasm","mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,11,4.1,no,,,,, P145,83,G11,P145_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR105C,VID24,GID4,"Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; promotes proteasome-dependent catabolite degradation of FBPase","vacuole organization, transport, vesicle organization, cellular carbohydrate metabolic process, vesicle-mediated transport, cellular membrane organization, cellular protein catabolic process",molecular_function,"cytoplasmic membrane-bounded vesicle, membrane, cytoplasm","carbohydrate metabolic process, cytoplasmic membrane-bounded vesicle, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, other, protein catabolic process, transport, vesicle-mediated transport",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,0,0,no,,,,, P145,84,G12,P145_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR106W,PHO88,,"Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations",transport,molecular_function,"membrane, mitochondrion, cytoplasm","membrane, mitochondrion, molecular_function, transport",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,298,0,0,no,,,,, P145,85,H1,P145_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR107C,IML3,MCM19,"Protein with a role in kinetochore function, localizes to the outer kinetochore in a Ctf19p-dependent manner, interacts with Chl4p and Ctf19p","meiosis, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle, chromosome segregation",molecular_function,"nucleus, chromosome","cell cycle, chromosome, meiosis, molecular_function, nucleus, organelle organization and biogenesis, other, sporulation",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,2,1.1,no,,,,, P145,86,H2,P145_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR108W,AIM3,,Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss,biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,6,2.7,no,,,,, P145,87,H3,P145_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P145,88,H4,P145_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR111C,YSA1,RMA2,Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate,"cellular carbohydrate metabolic process, heterocycle metabolic process",hydrolase activity,"nucleus, mitochondrion, cytoplasm","biological_process, cytoplasm, hydrolase activity, mitochondrion, nucleus",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,218,1,0.5,no,,,,, P145,89,H5,P145_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR113W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CYC8",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,2,1.1,no,,,,, P145,90,H6,P145_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR114W,RAD16,PSO5,Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex,"protein modification process, response to stress, chromosome organization, DNA metabolic process, cellular protein catabolic process","ligase activity, hydrolase activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, hydrolase activity, ligase activity, nucleus, organelle organization and biogenesis, other, protein catabolic process, protein modification process, response to stress",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,2,0.6,no,,,,, P145,91,H7,P145_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR115C,LYS2,,"Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p",cellular amino acid and derivative metabolic process,oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, oxidoreductase activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,8,4.1,no,,,,, P145,92,H8,P145_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR116C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TKL2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,2,0.7,no,,,,, P145,93,H9,P145_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR117C,TKL2,,"Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids","cofactor metabolic process, cellular carbohydrate metabolic process",transferase activity,"nucleus, cytoplasm","carbohydrate metabolic process, cofactor metabolic process, cytoplasm, nucleus, transferase activity, vitamin metabolic process",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,3,1.7,no,,,,, P145,94,H10,P145_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR119W,MUD1,U1A;U1-A,"U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing",RNA metabolic process,RNA binding,nucleus,"RNA binding, RNA metabolic process, nucleus",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,3,1.3,no,,,,, P145,95,H11,P145_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR120C,CBP6,,Mitochondrial translational activator of the COB mRNA; phosphorylated,translation,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, translation",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,1,0.6,no,,,,, P145,96,H12,P145_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR126C,TPS1,TSS1;GLC6;GGS1;FDP1;CIF1;BYP1,"Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway","response to stress, cellular carbohydrate metabolic process",transferase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, response to chemical stimulus, response to stress, transferase activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,4,1.8,no,,,,, P146,1,A1,P146_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR127C,VMA2,ATPSV;VAT2,"Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm","transport, cellular homeostasis","transporter activity, hydrolase activity","membrane, vacuole, cytoplasm","cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,20,9.5,no,,,,, P146,2,A2,P146_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR128C,ATG14,APG14;CVT12,Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34/15/30p); Atg14p targets complex I to the phagophore assembly site (PAS); required for localizing additional ATG proteins to the PAS; homolog of human Barkor,"transport, response to stress, cellular membrane organization, cellular protein catabolic process",transferase activity,"membrane fraction, vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane fraction, membrane organization and biogenesis, protein catabolic process, response to stress, transferase activity, vacuole",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,20,8.4,no,,,,, P146,3,A3,P146_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR129C,OPY1,,"Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","conjugation, cytoplasm, mitochondrion, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,2,0.6,no,,,,, P146,4,A4,P146_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR130C,SHE3,,Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance,DNA metabolic process,RNA binding,"cellular bud, cell cortex, site of polarized growth, cytoskeleton, cytoplasm","DNA metabolic process, RNA binding, cell cortex, cellular bud, cytoplasm, cytoskeleton, organelle organization and biogenesis, other, site of polarized growth",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,268,12,4.5,no,,,,, P146,5,A5,P146_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR132C,AGP2,,"High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease","transport, response to stress, cellular lipid metabolic process",transporter activity,"endomembrane system, vacuole, membrane, endoplasmic reticulum, cytoplasm, plasma membrane","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, plasma membrane, response to stress, transport, transporter activity, vacuole",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,14,5.1,no,,,,, P146,6,A6,P146_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR133C,HSL7,,"Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p",cell cycle,transferase activity,"cellular bud, site of polarized growth","cell cycle, cellular bud, site of polarized growth, transferase activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,14,7.1,no,,,,, P146,7,A7,P146_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR134W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,8,2.9,no,,,,, P146,8,A8,P146_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR137W,,,Protein of unknown function; localized to the cytoplasm; binds to Replication Protein A (RPA); also interacts with Sgt2p; YBR137W is not an essential gene,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,0,0,no,,,,, P146,9,A9,P146_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR138C,,HDR1,"Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,4,1.2,no,,,,, P146,10,A10,P146_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR139W,,,"Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner",other,"peptidase activity, hydrolase activity","vacuole, cytoplasm","cytoplasm, hydrolase activity, other, peptidase activity, vacuole",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,4,1.7,no,,,,, P146,11,A11,P146_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR141C,,,Putative S-adenosylmethionine-dependent methyltransferase; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene,biological_process,transferase activity,"nucleus, nucleolus","biological_process, molecular_function, nucleolus",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,3,1.2,no,,,,, P146,12,A12,P146_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR144C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR144C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,12,6.5,no,,,,, P146,13,B1,P146_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR145W,ADH5,,Alcohol dehydrogenase isoenzyme V; involved in ethanol production,"cofactor metabolic process, cellular carbohydrate metabolic process, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, nucleus, oxidoreductase activity, vitamin metabolic process",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,8,4.2,no,,,,, P146,14,B2,P146_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR146W,MRPS9,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,7,3.6,no,,,,, P146,15,B3,P146_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR147W,RTC2,RRT11,Protein of unknown function; identified in a screen for mutants with decreased levels of rDNA transcription; detected in highly purified mitochondria; null mutant suppresses cdc13-1; similar to a G-protein coupled receptor from S. pombe,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,5,2.4,no,,,,, P146,16,B4,P146_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR148W,YSW1,,"Protein required for normal prospore membrane formation; interacts with Gip1p, which is the meiosis-specific regulatory subunit of the Glc7p protein phosphatase; expressed specifically in spores and localizes to the prospore membrane","sporulation resulting in formation of a cellular spore, cellular component morphogenesis, cellular membrane organization",molecular_function,membrane,"biological_process, cellular_component, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,4,1.7,no,,,,, P146,17,B5,P146_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR149W,ARA1,,"NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; purified as homodimer; naturally occurs with a N-terminus degradation product",cellular carbohydrate metabolic process,oxidoreductase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, oxidoreductase activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,3,1.5,no,,,,, P146,18,B6,P146_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR151W,APD1,,"Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,10,5.2,no,,,,, P146,19,B7,P146_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR156C,SLI15,,"Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly","cytokinesis, protein modification process, chromosome segregation",enzyme regulator activity,cytoskeleton,"cytokinesis, cytoskeleton, enzyme regulator activity, other, protein modification process",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,16,9.5,no,,,,, P146,20,B8,P146_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR157C,ICS2,,"Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,6,1.9,no,,,,, P146,21,B9,P146_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR158W,AMN1,CST13;ICS4,"Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)","signaling process, cell cycle",protein binding,"cellular bud, nucleus, cytoplasm","cell cycle, cellular bud, cytoplasm, nucleus, protein binding",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,1,0.4,no,,,,, P146,22,B10,P146_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR159W,IFA38,,"Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides",cellular lipid metabolic process,oxidoreductase activity,"membrane, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, membrane, oxidoreductase activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,10,3.7,no,,,,, P146,23,B11,P146_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR161W,CSH1,,"Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p",cellular lipid metabolic process,transferase activity,"vacuole, cytoplasm","cytoplasm, lipid metabolic process, transferase activity, vacuole",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,4,2.2,no,,,,, P146,24,B12,P146_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR162C,TOS1,,"Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C",biological_process,molecular_function,"cell wall, vacuole, cytoplasm","cell wall, cytoplasm, molecular_function, response to chemical stimulus, vacuole",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,4,2.2,no,,,,, P146,25,C1,P146_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR162W-A,YSY6,,Protein whose expression suppresses a secretory pathway mutation in E. coli; has similarity to the mammalian RAMP4 protein involved in secretion,transport,molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, transport",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,12,6.1,no,,,,, P146,26,C2,P146_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR163W,EXO5,DEM1,"Mitochondrial 5'-3' exonuclease and sliding exonuclease, required for mitochondrial genome maintenance; distantly related to the RecB nuclease domain of bacterial RecBCD recombinases; may be regulated by the transcription factor Ace2",mitochondrion organization,hydrolase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,2,1.1,no,,,,, P146,27,C3,P146_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR164C,ARL1,DLP2,"Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor","transport, vesicle-mediated transport",hydrolase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, hydrolase activity, other, transport, vesicle-mediated transport",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,32,10.5,no,,,,, P146,28,C4,P146_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR165W,UBS1,,Ubiquitin-conjugating enzyme suppressor that functions as a general positive regulator of Cdc34p activity; nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity,"transport, protein modification process",molecular_function,nucleus,"molecular_function, nucleus, protein modification process, transport",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,30,9.4,no,,,,, P146,29,C5,P146_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR166C,TYR1,,"Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",oxidoreductase activity,cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, oxidoreductase activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,291,0,0,no,,,,, P146,30,C6,P146_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR170C,NPL4,HRD4,"Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation",cellular protein catabolic process,molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, protein catabolic process",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,14,6.8,no,,,,, P146,31,C7,P146_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR171W,SEC66,SEC71;HSS1,"Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER",transport,transporter activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, other, transport, transporter activity",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,311,5,1.6,no,,,,, P146,32,C8,P146_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR172C,SMY2,,Protein of unknown function involved in COPII vesicle formation; interacts with the Sec23p/Sec24p subcomplex; overexpression suppresses the temperature sensitivity of a myo2 mutant; has similarity to S. pombe Mpd2,"transport, vesicle-mediated transport",molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, molecular_function, transport, vesicle-mediated transport",,,2_3,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,8,4.3,no,,,,, P146,33,C9,P146_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL001W,RMD1,,Cytoplasmic protein required for sporulation,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,12,3.7,no,,,,, P146,34,C10,P146_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL002C,NHP10,HMO2,"Protein related to mammalian high mobility group proteins; preferentially binds DNA ends, protecting them from exonucleatic cleavage; likely component of the chromatin-remodeling complex INO80 complex; proposed to be involved in DNA repair","response to stress, chromosome organization, DNA metabolic process",DNA binding,"nucleus, chromosome","molecular_function, nucleus, organelle organization and biogenesis",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,14,5.1,no,,,,, P146,35,C11,P146_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL005C,MED2,,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,4,1.3,no,,,,, P146,36,C12,P146_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL006W,PTC1,TPD1;KCS2;CWH47,"Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p, inactivating osmosensing MAPK cascade; involved in Fus3p activation during pheromone response; deletion affects precursor tRNA splicing, mitochondrial inheritance, and sporulation","signaling process, mitochondrion organization, response to chemical stimulus, protein modification process, response to stress, conjugation, RNA metabolic process","hydrolase activity, phosphoprotein phosphatase activity","nucleus, cytoplasm","RNA metabolic process, cytoplasm, hydrolase activity, nucleus, organelle organization and biogenesis, phosphoprotein phosphatase activity, protein modification process, response to stress, signal transduction",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,6,2.9,no,,,,, P146,37,D1,P146_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL009C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YDL010W; YDL009C is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,28,11.4,no,,,,, P146,38,D2,P146_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL010W,GRX6,,Cis-golgi localized monothiol glutaredoxin that binds an iron-sulfur cluster; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; functional overlap with GRX7,"response to chemical stimulus, response to stress","oxidoreductase activity, protein binding","endomembrane system, vacuole, membrane, endoplasmic reticulum, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, endoplasmic reticulum, membrane, other, oxidoreductase activity, protein binding, response to chemical stimulus, response to stress, vacuole",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,18,6.5,no,,,,, P146,39,D3,P146_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL011C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the uncharacterized ORF YDL010W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,12,6,no,,,,, P146,40,D4,P146_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL012C,,,Plasma membrane protein of unknown function; may contribute to Non-homologous end-joining (NHEJ) based on double deletion with htz1; YDL012C is not an essential gene,biological_process,molecular_function,"membrane, plasma membrane","biological_process, molecular_function, plasma membrane",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,210,8,3.8,no,,,,, P146,41,D5,P146_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL013W,SLX5,ULS2;HEX3,"Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers","response to stress, chromosome organization, DNA metabolic process, protein modification process","protein binding, ligase activity",nucleus,"ligase activity, organelle organization and biogenesis, other, protein binding, protein modification process, response to stress",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,8,2.8,no,,,,, P146,42,D6,P146_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL018C,ERP3,,"Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport","transport, vesicle-mediated transport",molecular_function,membrane,"membrane, molecular_function, vesicle-mediated transport",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,3,1.5,no,,,,, P146,43,D7,P146_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL019C,OSH2,,"Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability","transport, vesicle-mediated transport, cellular membrane organization","lipid binding, transporter activity","cell cortex, cellular bud, membrane, site of polarized growth, endoplasmic reticulum, cytoplasm, plasma membrane","anatomical structure morphogenesis, cellular bud, endoplasmic reticulum, lipid binding, membrane organization and biogenesis, plasma membrane, site of polarized growth, transport, vesicle-mediated transport",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,2,1,no,,,,, P146,44,D8,P146_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL020C,RPN4,UFD5;SON1,Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses,"transcription, response to chemical stimulus, response to stress, cell cycle, DNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, cell cycle, other, protein catabolic process, response to chemical stimulus, response to stress, transcription, transcription regulator activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,8,4.1,no,,,,, P146,45,D9,P146_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL021W,GPM2,,"Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event",biological_process,"molecular_function, isomerase activity",cytoplasm,"biological_process, cytoplasm, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,10,3.3,no,,,,, P146,46,D10,P146_D10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P146,47,D11,P146_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL022W,GPD1,OSR5;OSG1;HOR1;DAR1,"NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p","response to stress, cofactor metabolic process, cellular homeostasis",oxidoreductase activity,"peroxisome, nucleus, cytoplasm","cellular homeostasis, cofactor metabolic process, cytoplasm, oxidoreductase activity, peroxisome, response to stress, vitamin metabolic process",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,23,12.8,no,,,,, P146,48,D12,P146_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL023C,,SRF4,"Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,20,8.3,no,,,,, P146,49,E1,P146_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL024C,DIA3,,"Protein of unknown function, involved in invasive and pseudohyphal growth",pseudohyphal growth,hydrolase activity,cell wall,"cell wall, hydrolase activity, other, pseudohyphal growth",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,10,5.3,no,,,,, P146,50,E2,P146_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL025C,RTK1,,"Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1",biological_process,"transferase activity, protein kinase activity",cellular_component,"biological_process, cellular_component, protein kinase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,20,6,no,,,,, P146,51,E3,P146_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL026W,,,"Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,16,8.2,no,,,,, P146,52,E4,P146_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL027C,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,16,7.5,no,,,,, P146,53,E5,P146_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL032W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene SLM3/YDL033C; YDL032W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,246,28,11.4,no,,,,, P146,54,E6,P146_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL033C,SLM3,MTU1;MTO2,"tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)",RNA metabolic process,transferase activity,"mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, transferase activity, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,14,4.1,no,,,,, P146,55,E7,P146_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL034W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps with verified gene GPR1/YDL035C; YDL034W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,290,6,2.1,no,,,,, P146,56,E8,P146_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL035C,GPR1,,"Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis","pseudohyphal growth, response to chemical stimulus",signal transducer activity,"membrane, plasma membrane","other, plasma membrane, pseudohyphal growth, response to chemical stimulus, signal transducer activity, signal transduction",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,1,0.6,no,,,,, P146,57,E9,P146_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL036C,PUS9,,"Mitochondrial tRNA:pseudouridine synthase, catalyzes the formation of pseudouridine at position 32 in mitochondrial tRNAs; contains an N-terminal mitochondrial targeting sequence",RNA metabolic process,isomerase activity,"nucleus, mitochondrion, cytoplasm","RNA metabolic process, cytoplasm, isomerase activity, mitochondrion, nucleus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,272,14,5.1,no,,,,, P146,58,E10,P146_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL037C,BSC1,,"Protein of unconfirmed function, similar to cell surface flocculin Muc1p; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,33,13.8,no,,,,, P146,59,E11,P146_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL038C,,,,,,,,,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,9,4.9,no,,,,, P146,60,E12,P146_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL039C,PRM7,YDL038C,"Pheromone-regulated protein, predicted to have one transmembrane segment; promoter contains Gcn4p binding elements",conjugation,molecular_function,membrane,"conjugation, membrane, molecular_function, response to chemical stimulus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,31,15.7,no,,,,, P146,61,F1,P146_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL040C,NAT1,NAA15;AAA1,"Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing",protein modification process,transferase activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, protein modification process, ribosome, transferase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,32,13.7,no,,,,, P146,62,F2,P146_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL041W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene SIR2/YDL042C",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P146,63,F3,P146_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL042C,SIR2,MAR1,"Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication","response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process",hydrolase activity,"nucleus, nucleolus, chromosome","DNA metabolic process, RNA metabolic process, chromosome, hydrolase activity, nucleolus, nucleus, organelle organization and biogenesis, other, response to stress, transcription",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P146,64,F4,P146_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL044C,MTF2,NAM1,Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription,"translation, RNA metabolic process",RNA binding,"mitochondrion, cytoplasm","RNA binding, RNA metabolic process, mitochondrion, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,14,6.7,no,,,,, P146,65,F5,P146_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL045W-A,MRP10,,Mitochondrial ribosomal protein of the small subunit; contains twin cysteine-x9-cysteine motifs,"mitochondrion organization, translation, protein complex biogenesis",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,14,6,no,,,,, P146,66,F6,P146_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL046W,NPC2,,"Functional homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes",transport,molecular_function,"vacuole, cytoplasm","cytoplasm, molecular_function, transport, vacuole",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,26,9.2,no,,,,, P146,67,F7,P146_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL048C,STP4,,"Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p",biological_process,DNA binding,"nucleus, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function, nucleus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,5,2.5,no,,,,, P146,68,F8,P146_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL049C,KNH1,,"Protein with similarity to Kre9p, which is involved in cell wall beta 1,6-glucan synthesis; overproduction suppresses growth defects of a kre9 null mutant; required for propionic acid resistance",cellular carbohydrate metabolic process,molecular_function,"cell wall, extracellular region","carbohydrate metabolic process, cell wall, cell wall organization and biogenesis, extracellular region, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,30,14.6,no,,,,, P146,69,F9,P146_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL050C,,,"Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,12,4.7,no,,,,, P146,70,F10,P146_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL051W,LHP1,La protein;YLA1;LAH1,RNA binding protein required for maturation of tRNA and U6 snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen,RNA metabolic process,RNA binding,"nucleus, nucleolus","RNA binding, RNA metabolic process, nucleolus, nucleus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,9,5.2,no,,,,, P146,71,F11,P146_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL052C,SLC1,,"1-acyl-sn-glycerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes",cellular lipid metabolic process,transferase activity,cytoplasm,"cytoplasm, lipid metabolic process, transferase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,12,6.3,no,,,,, P146,72,F12,P146_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL053C,PBP4,,"Pbp1p binding protein, interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system; also interacts with Lsm12p in a copurification assay",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,20,7.2,no,,,,, P146,73,G1,P146_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL054C,MCH1,,"Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport",transport,transporter activity,membrane,"membrane, transport, transporter activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,6,3.1,no,,,,, P146,74,G2,P146_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL056W,MBP1,,"Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes","transcription, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, RNA metabolic process, cell cycle, nucleus, transcription, transcription regulator activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,6,2.7,no,,,,, P146,75,G3,P146_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL057W,,,Putative protein of unknown function; YDL057W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,14,4.4,no,,,,, P146,76,G4,P146_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL059C,RAD59,,Protein involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing; anneals complementary single-stranded DNA; homologous to Rad52p,"response to stress, chromosome organization, DNA metabolic process","DNA binding, protein binding",nucleus,"DNA binding, DNA metabolic process, nucleus, organelle organization and biogenesis, protein binding, response to stress",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,70,34,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P146,77,G5,P146_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL062W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YDL063C; YDL062W is not essential",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,24,12.1,no,,,,, P146,78,G6,P146_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL063C,,,Protein required for biogenesis of the large ribosomal subunit; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus,ribosome biogenesis,molecular_function,"nucleus, cytoplasm","cytoplasm, molecular_function, nucleus, ribosome biogenesis",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,2,1,no,,,,, P146,79,G7,P146_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL065C,PEX19,PAS12,"Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane","transport, peroxisome organization",protein binding,"peroxisome, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, organelle organization and biogenesis, other, peroxisome, protein binding, transport",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,13,7.3,no,,,,, P146,80,G8,P146_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL066W,IDP1,,"Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes",cellular amino acid and derivative metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, mitochondrion, other, oxidoreductase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,4,2.1,no,,,,, P146,81,G9,P146_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL067C,COX9,,"Subunit VIIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,26,8.4,no,,,,, P146,82,G10,P146_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL068W,,,"Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,6,3.5,no,,,,, P146,83,G11,P146_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL069C,CBS1,,"Mitochondrial translational activator of the COB mRNA; membrane protein that interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader",translation,RNA binding,"membrane, mitochondrial envelope, ribosome, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, ribosome, translation, translation regulator activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,6,3.8,no,,,,, P146,84,G12,P146_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL070W,BDF2,,Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p,biological_process,protein binding,nucleus,"biological_process, molecular_function, nucleus",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,48,19.8,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P146,85,H1,P146_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL071C,,IRC1,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF BDF2/YDL070W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,70,20.7,no,,,,, P146,86,H2,P146_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL072C,YET3,,Protein of unknown function; YET3 null mutant decreases the level of secreted invertase; homolog of human BAP31 protein,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,20,8.1,no,,,,, P146,87,H3,P146_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P146,88,H4,P146_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL073W,,,Putative protein of unknown function; YDL073W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,10,4.9,no,,,,, P146,89,H5,P146_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL074C,BRE1,,"E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control","signaling process, transcription, protein modification process, response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process",ligase activity,"nucleus, chromosome","DNA metabolic process, RNA metabolic process, ligase activity, nucleus, organelle organization and biogenesis, protein modification process, response to chemical stimulus, transcription, transposition",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,14,6.4,no,,,,, P146,90,H6,P146_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL076C,RXT3,,Subunit of the RPD3L complex; involved in histone deacetylation,"chromosome organization, transcription, protein modification process, RNA metabolic process",molecular_function,"nucleus, chromosome","RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, protein modification process, transcription",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,10,3.1,no,,,,, P146,91,H7,P146_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL077C,VAM6,VPS39;VPL22;VPL18;CVT4,Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by facilitating guanine nucleotide exchange on small guanosine triphosphatase Ypt7p,"vacuole organization, transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular membrane organization","lipid binding, enzyme regulator activity","vacuole, membrane, cytoplasm","cytoplasm, enzyme regulator activity, membrane, membrane organization and biogenesis, organelle organization and biogenesis, vacuole",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,5,2.9,no,,,,, P146,92,H8,P146_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL078C,MDH3,,"Peroxisomal malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle","cofactor metabolic process, cellular carbohydrate metabolic process, cellular lipid metabolic process",oxidoreductase activity,"peroxisome, cytoplasm","carbohydrate metabolic process, cofactor metabolic process, cytoplasm, lipid metabolic process, other, oxidoreductase activity, peroxisome, vitamin metabolic process",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,2,0.7,no,,,,, P146,93,H9,P146_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL079C,MRK1,,Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation,"response to stress, protein modification process","transferase activity, protein kinase activity",cellular_component,"cellular_component, protein catabolic process, protein kinase activity, protein modification process, response to stress, transferase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,294,18,6.1,no,,,,, P146,94,H10,P146_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL080C,THI3,KID1,"Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis","transcription, cellular amino acid and derivative metabolic process, vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process, RNA metabolic process",lyase activity,"nucleus, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, cytoplasm, lyase activity, nucleus, transcription, vitamin metabolic process",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,12,7,no,,,,, P146,95,H11,P146_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL081C,RPP1A,RPLA1,"Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,22,6.6,no,,,,, P146,96,H12,P146_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL082W,RPL13A,L13A,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential for viability; has similarity to rat L13 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,16,5.8,no,,,,, P147,1,A1,P147_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL083C,RPS16B,rp61R;S16B,Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins,"translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,2,1.1,no,,,,, P147,2,A2,P147_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL085W,NDE2,NDH2,"Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain","cofactor metabolic process, cellular carbohydrate metabolic process, generation of precursor metabolites and energy",oxidoreductase activity,"mitochondrion, cytoplasm","cofactor metabolic process, generation of precursor metabolites and energy, mitochondrion, oxidoreductase activity, vitamin metabolic process",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,6,3.1,no,,,,, P147,3,A3,P147_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL086W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL086W is not an essential gene",biological_process,hydrolase activity,"mitochondrion, cytoplasm","biological_process, cytoplasm, hydrolase activity, mitochondrion",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,12,4.7,no,,,,, P147,4,A4,P147_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL088C,ASM4,NUP59,"Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p","transport, ribosome biogenesis, protein complex biogenesis, nucleus organization",structural molecule activity,"nucleus, membrane, endomembrane system","endomembrane system, membrane, nuclear organization and biogenesis, nucleus, organelle organization and biogenesis, structural molecule activity, transport",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,26,9.4,no,,,,, P147,5,A5,P147_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL089W,NUR1,,"Protein of unknown function; interacts with Csm1p, Lrs4p; required for rDNA repeat stability; null mutant causes increase in unequal sister-chromatid exchange; GFP-fusion protein localizes to the nuclear periphery, possible Cdc28p substrate","chromosome organization, DNA metabolic process",molecular_function,nucleus,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,8,4.5,no,,,,, P147,6,A6,P147_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL090C,RAM1,STE16;SGP2;SCG2;FUS8;DPR1,Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit,protein modification process,transferase activity,cytoplasm,"cytoplasm, protein modification process, transferase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,186,10,5.4,no,,,,, P147,7,A7,P147_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL091C,UBX3,,"UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,6,3,no,,,,, P147,8,A8,P147_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL093W,PMT5,,"Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt3p, can instead interact with Pmt2p in some conditions; target for new antifungals","cellular carbohydrate metabolic process, protein modification process",transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, protein modification process, transferase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,249,11,4.4,no,,,,, P147,9,A9,P147_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL094C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verfied gene PMT5/YDL093W; YDL094C is not essential",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,28,13,no,,,,, P147,10,A10,P147_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL095W,PMT1,,"Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; one of seven related proteins involved in O-glycosylation which is essential for cell wall rigidity","cellular carbohydrate metabolic process, protein modification process",transferase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, membrane, protein modification process, transferase activity",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,202,6,3,no,,,,, P147,11,A11,P147_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR438W,THI74,,Mitochondrial transporter repressible by thiamine,biological_process,molecular_function,"membrane, mitochondrion, cytoplasm","biological_process, membrane, mitochondrion, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,22,9.5,no,,,,, P147,12,A12,P147_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR439W,LRS4,,"Nucleolar protein that forms a complex with Csm1p, and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation","transcription, chromosome segregation, meiosis, chromosome organization, cell cycle, RNA metabolic process",molecular_function,"nucleus, chromosome, nucleolus","RNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, transcription",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,92,39,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P147,13,B1,P147_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR440W,DOT1,KMT4;PCH1,"Nucleosomal histone H3-Lys79 methylase; methylation is required for telomeric silencing, meiotic checkpoint control, and DNA damage response","signaling process, transcription, protein modification process, response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process","transferase activity, protein binding",nucleus,"DNA metabolic process, RNA metabolic process, cell cycle, meiosis, nucleus, organelle organization and biogenesis, protein binding, protein modification process, response to stress, signal transduction, transcription, transferase activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,280,8,2.9,no,,,,, P147,14,B2,P147_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR441C,APT2,,"Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity",biological_process,"transferase activity, molecular_function",cytoplasm,"biological_process, cytoplasm, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,14,4.5,no,,,,, P147,15,B3,P147_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR442W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,347,0,0,no,,,,, P147,16,B4,P147_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR443C,SSN2,MED13;RYE3;UME2;SRB9;SCA1;NUT8,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,8,2.7,no,,,,, P147,17,B5,P147_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR446W,ECM11,,"Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure","fungal-type cell wall organization, meiosis, cell cycle, DNA metabolic process",molecular_function,nucleus,"DNA metabolic process, cell cycle, cell wall organization and biogenesis, meiosis, molecular_function, nucleus",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,80,32.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P147,18,B6,P147_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR447C,RPS17B,rp51B;S17B;RPL51B;RP51B,Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Ap and has similarity to rat S17 ribosomal protein,"translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,7,3.3,no,,,,, P147,19,B7,P147_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR448W,ADA2,SWI8,"Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes","transcription, protein modification process, chromosome organization, RNA metabolic process","transcription regulator activity, transferase activity, lipid binding, protein binding",nucleus,"nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription regulator activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,21,10.5,no,,,,, P147,20,B8,P147_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR450W,RPS18A,S18A,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins,"transport, translation, ribosome biogenesis, RNA metabolic process",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,244,0,0,no,,,,, P147,21,B9,P147_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR451C,YHP1,,"One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval","transcription, meiosis, cell cycle, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, chromosome","DNA binding, RNA metabolic process, cell cycle, chromosome, meiosis, nucleus, transcription, transcription regulator activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,9,4.7,no,,,,, P147,22,B10,P147_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR452W,PPN1,PHM5,Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer,other,hydrolase activity,"nucleus, membrane, vacuole, cytoplasm","cytoplasm, hydrolase activity, membrane, other, vacuole",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,2,0.6,no,,,,, P147,23,B11,P147_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR453C,TSA2,cTPxII,"Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants","response to stress, cellular homeostasis, response to chemical stimulus",oxidoreductase activity,cytoplasm,"cellular homeostasis, cytoplasm, oxidoreductase activity, response to chemical stimulus, response to stress",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,322,8,2.5,no,,,,, P147,24,B12,P147_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR455C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YDR456W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,2,0.6,no,,,,, P147,25,C1,P147_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR456W,NHX1,VPL27;NHA2;VPS44,"Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; required for osmotolerance to acute hypertonic shock","transport, vesicle-mediated transport, cellular homeostasis",transporter activity,"membrane, cytoplasm","cellular homeostasis, cytoplasm, transport, transporter activity, vesicle-mediated transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,265,4,1.5,no,,,,, P147,26,C2,P147_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR457W,TOM1,,E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones,"transport, ribosome biogenesis, cell cycle, protein modification process, nucleus organization, RNA metabolic process",ligase activity,"nucleus, nucleolus","cell cycle, ligase activity, nuclear organization and biogenesis, nucleolus, nucleus, other, protein modification process, transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,4,1.7,no,,,,, P147,27,C3,P147_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR458C,HEH2,,"Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle",biological_process,molecular_function,"nucleus, endomembrane system","biological_process, endomembrane system, molecular_function, nucleus",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,7,3.1,no,,,,, P147,28,C4,P147_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR459C,PFA5,,Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain,protein modification process,transferase activity,"membrane, plasma membrane","cellular_component, protein modification process, transferase activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,5,2,no,,,,, P147,29,C5,P147_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR462W,MRPL28,YmL28,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,15,7.9,no,,,,, P147,30,C6,P147_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR463W,STP1,SSY2;BAP1,"Transcription factor, undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing","transcription, RNA metabolic process",transcription regulator activity,nucleus,"DNA binding, RNA metabolic process, nucleus, transcription, transcription regulator activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,10,3.1,no,,,,, P147,31,C7,P147_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR465C,RMT2,,Arginine N5 methyltransferase; methylates ribosomal protein Rpl12 (L12) on Arg67,protein modification process,transferase activity,"nucleus, cytoplasm","cytoplasm, nucleus, protein modification process, ribosome biogenesis, transferase activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,237,6,2.5,no,,,,, P147,32,C8,P147_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR466W,PKH3,,"Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant",signaling process,"transferase activity, protein kinase activity",cellular_component,"cell wall organization and biogenesis, cellular_component, protein kinase activity, signal transduction",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,4,1.4,no,,,,, P147,33,C9,P147_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR467C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,12,7.5,no,,,,, P147,34,C10,P147_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR469W,SDC1,SAF19;CPS25,"Subunit of the COMPASS (Set1C) complex, which methylates lysine 4 of histone H3 and is required in chromatin silencing at telomeres; contains a Dpy-30 domain that mediates interaction with Bre2p; similar to C. elegans and human DPY-30","chromosome organization, transcription, protein modification process, RNA metabolic process",transferase activity,nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein modification process, transcription, transferase activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,183,5,2.7,no,,,,, P147,35,C11,P147_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR470C,UGO1,,Protein of unknown function; outer membrane component of the mitochondrial fusion machinery; Ugo1p bind directly to Fzo1p and Mgm1p and thereby link these two GTPases during mitochondrial fusion,"transport, mitochondrion organization, cellular membrane organization",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, transport, transporter activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,9,4.4,no,,,,, P147,36,C12,P147_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR471W,RPL27B,L27B,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Ap and has similarity to rat L27 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,10,3.9,no,,,,, P147,37,D1,P147_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR475C,JIP4,YDR474C,"Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,10,3.3,no,,,,, P147,38,D2,P147_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR476C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene,biological_process,molecular_function,"endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,3,1.4,no,,,,, P147,39,D3,P147_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR479C,PEX29,,"Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p",peroxisome organization,molecular_function,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, molecular_function, organelle organization and biogenesis, peroxisome",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,0,0,no,,,,, P147,40,D4,P147_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR480W,DIG2,RST2,"Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription",other,protein binding,nucleus,"nucleus, other, protein binding",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,296,6,2,no,,,,, P147,41,D5,P147_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR481C,PHO8,phoH,"Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides",protein modification process,hydrolase activity,"membrane, vacuole, cytoplasm","cytoplasm, hydrolase activity, membrane, protein modification process, vacuole",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,20,6.1,no,,,,, P147,42,D6,P147_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR482C,CWC21,,Protein involved in RNA splicing by the spliceosome; component of a complex containing Cef1p; interacts genetically with ISY1 and BUD13; may bind RNA; has similarity to S. pombe Cwf21p,RNA metabolic process,molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,235,16,6.8,no,,,,, P147,43,D7,P147_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR483W,KRE2,MNT1,"Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cell wall organization and biogenesis, protein modification process, transferase activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,243,11,4.5,no,,,,, P147,44,D8,P147_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR484W,VPS52,SAC2,"Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; involved in localization of actin and chitin","transport, vesicle-mediated transport",protein binding,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein binding, transport, vesicle-mediated transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,6,2.1,no,,,,, P147,45,D9,P147_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR485C,VPS72,SWC2,"Htz1p-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting",chromosome organization,protein binding,"nucleus, chromosome, cytoplasm","cytoplasm, nucleus, organelle organization and biogenesis, protein binding",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,100,29.8,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P147,46,D10,P147_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR486C,VPS60,CHM5;MOS10,Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport; required for normal filament maturation during pseudohyphal growth; may function in targeting cargo proteins for degradation; interacts with Vta1p,"transport, vesicle-mediated transport",molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, membrane, molecular_function, other, response to chemical stimulus, transport, vacuole, vesicle-mediated transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,0,0,no,,,,, P147,47,D11,P147_D11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P147,48,D12,P147_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR488C,PAC11,,"Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortical cytoplasmic microtubule capture site with Num1p; null mutant is defective in nuclear migration, essential in the absence of CIN8",transport,"motor activity, hydrolase activity","cytoskeleton, cytoplasm","cytoskeleton, cytoskeleton organization and biogenesis, motor activity, organelle organization and biogenesis, transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,9,4.7,no,,,,, P147,49,E1,P147_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR490C,PKH1,,"Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p","transport, vesicle-mediated transport, signaling process, protein modification process, cellular membrane organization","transferase activity, protein kinase activity","cell cortex, cytoplasm","cell wall organization and biogenesis, cytoplasm, membrane organization and biogenesis, protein kinase activity, protein modification process, signal transduction, transport, vesicle-mediated transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,5,2.5,no,,,,, P147,50,E2,P147_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR491C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,15,7.5,no,,,,, P147,51,E3,P147_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR492W,IZH1,,"Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc","cellular lipid metabolic process, cellular homeostasis, response to chemical stimulus",other,"membrane, endoplasmic reticulum, cytoplasm","cellular homeostasis, endoplasmic reticulum, lipid metabolic process, membrane, other, response to chemical stimulus",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,306,14,4.6,no,,,,, P147,52,E4,P147_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR494W,RSM28,,Mitochondrial ribosomal protein of the small subunit; genetic interactions suggest a possible role in promoting translation initiation,translation,structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,4,2.2,no,,,,, P147,53,E5,P147_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR495C,VPS3,VPT17;VPL3;PEP6,"Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase","vacuole organization, transport, cellular homeostasis",molecular_function,cytoplasm,"cellular homeostasis, cytoplasm, molecular_function, organelle organization and biogenesis, transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,245,10,4.1,no,,,,, P147,54,E6,P147_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR496C,PUF6,,"Pumilio-homology domain protein that binds the 3' UTR of ASH1 mRNA and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA; also co-sediments with the 60S ribosomal subunit and is required for its biogenesis","translation, ribosome biogenesis","RNA binding, translation regulator activity","nucleus, ribosome, nucleolus, cytoplasm","RNA binding, RNA metabolic process, nucleolus, nucleus, ribosome biogenesis, transcription, transcription regulator activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,16,4.7,no,,,,, P147,55,E7,P147_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR497C,ITR1,,"Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p",transport,transporter activity,"membrane, plasma membrane","membrane, plasma membrane, transport, transporter activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,232,0,0,no,,,,, P147,56,E8,P147_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR501W,PLM2,,Forkhead Associated domain containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; induced in response to DNA damaging agents and deletion of telomerase; similar to TOS4,response to stress,other,"nucleus, chromosome","DNA binding, RNA metabolic process, cell cycle, nucleus, transcription, transcription regulator activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,0,0,no,,,,, P147,57,E9,P147_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR503C,LPP1,,"Lipid phosphate phosphatase, catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA",cellular lipid metabolic process,hydrolase activity,membrane,"hydrolase activity, lipid metabolic process, membrane",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,10,3.8,no,,,,, P147,58,E10,P147_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR504C,SPG3,,Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,7,3.2,no,,,,, P147,59,E11,P147_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR505C,PSP1,GIN5,Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition,biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,6,2.9,no,,,,, P147,60,E12,P147_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR506C,,,Possible membrane-localized protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,160,6,3.8,no,,,,, P147,61,F1,P147_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR507C,GIN4,ERC47,"Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p","cell budding, cytoskeleton organization, cytokinesis, protein modification process, protein complex biogenesis, cell cycle","transferase activity, protein kinase activity","cellular bud, site of polarized growth","anatomical structure morphogenesis, cell budding, cell cycle, cellular bud, cytokinesis, cytoskeleton organization and biogenesis, organelle organization and biogenesis, protein kinase activity, protein modification process, site of polarized growth",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,10,3.3,no,,,,, P147,62,F2,P147_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR508C,GNP1,,"High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, plasma membrane, transport, transporter activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,4,1.8,no,,,,, P147,63,F3,P147_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR509W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,10,4.1,no,,,,, P147,64,F4,P147_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR511W,ACN9,,"Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes",cellular carbohydrate metabolic process,molecular_function,"mitochondrial envelope, mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, mitochondrial envelope, mitochondrion, molecular_function, other",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,9,4.1,no,,,,, P147,65,F5,P147_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR512C,EMI1,,"Non-essential protein required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation; contains twin cysteine-x9-cysteine motifs","sporulation resulting in formation of a cellular spore, mitochondrion organization, transcription, protein complex biogenesis, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, cellular_component, molecular_function, sporulation, transcription",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,11,6.2,no,,,,, P147,66,F6,P147_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR513W,GRX2,TTR1,"Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress","response to stress, cellular homeostasis, response to chemical stimulus","transferase activity, oxidoreductase activity","mitochondrion, cytoplasm","cellular homeostasis, cytoplasm, mitochondrion, oxidoreductase activity, response to chemical stimulus, response to stress, transferase activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,10,3.1,no,,,,, P147,67,F7,P147_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR514C,,,Putative protein of unknown function,biological_process,molecular_function,"nucleus, mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function, nucleus",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,0,0,no,,,,, P147,68,F8,P147_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR516C,EMI2,,Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression is regulated by glucose-repression transcription factors Mig1/2p,"sporulation resulting in formation of a cellular spore, transcription, RNA metabolic process",molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function, response to chemical stimulus, sporulation, transcription",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,6,3.3,no,,,,, P147,69,F9,P147_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR517W,GRH1,,"Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes","transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cell cycle, cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, molecular_function, organelle organization and biogenesis, transport, vesicle-mediated transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,8,4.2,no,,,,, P147,70,F10,P147_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR518W,EUG1,,"Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER",protein folding,"isomerase activity, oxidoreductase activity","endoplasmic reticulum, cytoplasm","endoplasmic reticulum, isomerase activity, oxidoreductase activity, protein folding",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,310,14,4.5,no,,,,, P147,71,F11,P147_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR519W,FPR2,FKB2,"Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking",biological_process,isomerase activity,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endomembrane system, endoplasmic reticulum, isomerase activity, membrane",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,5,2.9,no,,,,, P147,72,F12,P147_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR520C,URC2,RRT4,Putative Zn(II)2Cys6 motif containing transcription factor; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; similar to S. kluyveri Urc2p involved in uracil catabolism,"heterocycle metabolic process, cellular aromatic compound metabolic process",DNA binding,"nucleus, cytoplasm","aromatic compound metabolic process, cytoplasm, heterocycle metabolic process, molecular_function, nucleus",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,2,0.6,no,,,,, P147,73,G1,P147_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR521W,,,Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,11,4.7,no,,,,, P147,74,G2,P147_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR522C,SPS2,,"Protein expressed during sporulation, redundant with Sps22p for organization of the beta-glucan layer of the spore wall; S. pombe ortholog is a spore wall component","sporulation resulting in formation of a cellular spore, cellular component morphogenesis",molecular_function,"cell wall, membrane fraction","cell wall, cell wall organization and biogenesis, molecular_function, sporulation",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,6,3,no,,,,, P147,75,G3,P147_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR523C,SPS1,,"Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis","sporulation resulting in formation of a cellular spore, cellular component morphogenesis, protein modification process","transferase activity, protein kinase activity","nucleus, membrane, cytoplasm","cell wall organization and biogenesis, cytoplasm, membrane, nucleus, protein kinase activity, protein modification process, sporulation, transferase activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,1,0.6,no,,,,, P147,76,G4,P147_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR524C,AGE1,SAT1,"ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif","transport, vesicle-mediated transport",enzyme regulator activity,cytoplasm,"cytoplasm, enzyme regulator activity, transport, vesicle-mediated transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,4,2.2,no,,,,, P147,77,G5,P147_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR525W,API2,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 26% of ORF overlaps the dubious ORF YDR524C-A; insertion mutation in a cdc34-2 mutant background causes altered bud morphology",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,8,3.6,no,,,,, P147,78,G6,P147_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR528W,HLR1,,"Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A",fungal-type cell wall organization,molecular_function,cytoplasm,"cell wall organization and biogenesis, cytoplasm, molecular_function",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,4,1.3,no,,,,, P147,79,G7,P147_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR529C,QCR7,UCR7;CRO1;COR4,"Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly","mitochondrion organization, generation of precursor metabolites and energy, protein complex biogenesis, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, oxidoreductase activity, transporter activity",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,8,4.7,no,,,,, P147,80,G8,P147_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR530C,APA2,,"Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa1p",other,hydrolase activity,"nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, other",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,16,8.2,no,,,,, P147,81,G9,P147_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR533C,HSP31,,"Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site",biological_process,"peptidase activity, protein binding, hydrolase activity",other,"biological_process, hydrolase activity, other, peptidase activity, protein binding",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,296,12,4.1,no,,,,, P147,82,G10,P147_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR534C,FIT1,,"Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall",transport,molecular_function,cell wall,"cell wall, molecular_function, transport",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,195,2,1,no,,,,, P147,83,G11,P147_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL101W,,,Putative protein of unknown function; non-essential gene with similarity to YBR242W; interacts with the DNA helicase Hpr5p,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,302,2,0.7,no,,,,, P147,84,G12,P147_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL104C,VPS73,,Mitochondrial protein; mutation affects vacuolar protein sorting; putative transporter; member of the sugar porter family,transport,transporter activity,"mitochondrion, cytoplasm","mitochondrion, transport, transporter activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,217,0,0,no,,,,, P147,85,H1,P147_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL105W,ARC1,,"Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids","translation, cellular amino acid and derivative metabolic process, RNA metabolic process","RNA binding, lipid binding, enzyme regulator activity",cytoplasm,"RNA binding, RNA metabolic process, amino acid and derivative metabolic process, cytoplasm, enzyme regulator activity, other, translation",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,216,14,6.5,no,,,,, P147,86,H2,P147_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL107C,RMD9,,Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions suggest a role in delivering mt mRNAs to ribosomes; located on matrix face of the inner membrane and loosely associated with mitoribosomes,"translation, generation of precursor metabolites and energy, cellular respiration, RNA metabolic process",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","RNA metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, molecular_function, translation",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,332,26,7.8,no,,,,, P147,87,H3,P147_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P147,88,H4,P147_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL108C,,,"Protein of unknown function, predicted to be palmitoylated; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,251,2,0.8,no,,,,, P147,89,H5,P147_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL109W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the uncharacterized gene YGL108C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,207,4,1.9,no,,,,, P147,90,H6,P147_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL110C,CUE3,,"Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination",biological_process,protein binding,cytoplasm,"biological_process, cytoplasm, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,209,1,0.5,no,,,,, P147,91,H7,P147_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL114W,,,Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters,transport,transporter activity,membrane,"membrane, transport, transporter activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,277,0,0,no,,,,, P147,92,H8,P147_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL115W,SNF4,SCI1;CAT3,"Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis","transcription, peroxisome organization, protein modification process, cellular carbohydrate metabolic process, RNA metabolic process","transferase activity, protein kinase activity, enzyme regulator activity","nucleus, endomembrane system, membrane, cytoplasm, plasma membrane","RNA metabolic process, carbohydrate metabolic process, cytoplasm, endomembrane system, enzyme regulator activity, nucleus, organelle organization and biogenesis, other, plasma membrane, protein kinase activity, protein modification process, transcription, transferase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,171,2,1.2,no,,,,, P147,93,H9,P147_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL117W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,190,4,2.1,no,,,,, P147,94,H10,P147_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL118C,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,330,4,1.2,no,,,,, P147,95,H11,P147_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL121C,GPG1,,Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p; overproduction causes prion curing,signaling process,signal transducer activity,cellular_component,"cellular_component, other, signal transducer activity, signal transduction",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,191,1,0.5,no,,,,, P147,96,H12,P147_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL124C,MON1,AUT12,"Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate","transport, vesicle-mediated transport",molecular_function,"membrane, vacuole, cytoplasm","cytoplasm, membrane, molecular_function, other, transport, vacuole, vesicle-mediated transport",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,197,3,1.5,no,,,,, P148,1,A1,P148_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL126W,SCS3,FIT2B,"Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol",cellular lipid metabolic process,molecular_function,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,254,1,0.4,no,,,,, P148,2,A2,P148_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL127C,SOH1,MED31,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits,"transcription, chromosome segregation, response to stress, meiosis, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process",molecular_function,nucleus,"DNA metabolic process, RNA metabolic process, cell cycle, meiosis, molecular_function, nucleus, organelle organization and biogenesis, response to stress, transcription, transposition",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,72,23.4,no,,,,, P148,3,A3,P148_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL129C,RSM23,,"Mitochondrial ribosomal protein of the small subunit, has similarity to mammalian apoptosis mediator proteins; null mutation prevents induction of apoptosis by overproduction of metacaspase Mca1p","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, response to chemical stimulus, ribosome, structural molecule activity, translation",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,3,1.3,no,,,,, P148,4,A4,P148_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL131C,SNT2,,DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a role in regulation of expression of genes encoding amine transporters,biological_process,DNA binding,"nucleus, chromosome, cytoplasm","DNA binding, biological_process, cytoplasm, nucleus",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,222,6,2.7,no,,,,, P148,5,A5,P148_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL132W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene SNT2/YGL131C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,21,10.8,no,,,,, P148,6,A6,P148_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL133W,ITC1,,"Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1","chromosome organization, transcription, response to chemical stimulus, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, molecular_function, nucleus, organelle organization and biogenesis, response to chemical stimulus, transcription",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,0,0,no,,,,, P148,7,A7,P148_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL135W,RPL1B,L1B;SSM2,"N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Ap and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,10,3.2,no,,,,, P148,8,A8,P148_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL136C,MRM2,,"Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ","ribosome biogenesis, RNA metabolic process",transferase activity,"mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, organelle organization and biogenesis, ribosome biogenesis, transferase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,12,4.8,no,,,,, P148,9,A9,P148_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL138C,,,Putative protein of unknown function; has no significant sequence similarity to any known protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,11,5.4,no,,,,, P148,10,A10,P148_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL139W,FLC3,HUF3,"Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER",transport,transporter activity,"membrane, mitochondrion, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, membrane, mitochondrion, transport, transporter activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,23,11.9,no,,,,, P148,11,A11,P148_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL140C,,,Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane domains,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,5,2.2,no,,,,, P148,12,A12,P148_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL141W,HUL5,,"Ubiquitin-conjugating enzyme (E4), elongates polyubiquitin chains on substrate proteins; works in opposition to Ubp6p polyubiquitin-shortening activity; required for retrograde transport of misfolded proteins into cytoplasm during ERAD","protein modification process, cellular protein catabolic process",ligase activity,"nucleus, cytoplasm","cytoplasm, ligase activity, nucleus, other, protein catabolic process, protein modification process",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,72,23.1,no,,,,, P148,13,B1,P148_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL143C,MRF1,,"Mitochondrial translation release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability","mitochondrion organization, translation",RNA binding,"mitochondrion, cytoplasm","mitochondrion, translation, translation regulator activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,28,8.3,no,,,,, P148,14,B2,P148_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL144C,ROG1,,Protein with putative serine active lipase domain,cellular lipid metabolic process,hydrolase activity,cellular_component,"cellular_component, hydrolase activity, lipid metabolic process",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,308,26,8.4,no,,,,, P148,15,B3,P148_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL146C,RRT6,,"Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; contains two putative transmembrane spans, but no significant homology to other known proteins",biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,5,2.2,no,,,,, P148,16,B4,P148_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL147C,RPL9A,rp24;YL11;L9A;L8A,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,6,1.8,no,,,,, P148,17,B5,P148_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL148W,ARO2,,"Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process","lyase activity, oxidoreductase activity",cytoplasm,"amino acid and derivative metabolic process, aromatic compound metabolic process, cytoplasm, lyase activity, oxidoreductase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,22,9.6,no,,,,, P148,18,B6,P148_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL149W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF INO80/YGL150C.",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,3,1.5,no,,,,, P148,19,B7,P148_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL151W,NUT1,MED5,"Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription","transcription, RNA metabolic process",molecular_function,"nucleus, mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, molecular_function, nucleus, transcription",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,5,2.2,no,,,,, P148,20,B8,P148_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL152C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF PEX14/YGL153W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,3,1.7,no,,,,, P148,21,B9,P148_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL153W,PEX14,,"Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery; interacts with both PTS1 (Pex5p) and PTS2 (Pex7p), peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p","transport, peroxisome organization, protein complex biogenesis",protein binding,"peroxisome, membrane, cytoplasm","cytoplasm, membrane, organelle organization and biogenesis, peroxisome, protein binding, transport",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,2,1,no,,,,, P148,22,B10,P148_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL154C,LYS5,,Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine,"cellular amino acid and derivative metabolic process, protein modification process",transferase activity,cytoplasm,"amino acid and derivative metabolic process, cytoplasm, protein modification process, transferase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,12,6.9,no,,,,, P148,23,B11,P148_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL156W,AMS1,,"Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway",cellular carbohydrate metabolic process,hydrolase activity,"membrane, vacuole, cytoplasm","carbohydrate metabolic process, cytoplasm, hydrolase activity, membrane, vacuole",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,11,6.2,no,,,,, P148,24,B12,P148_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL157W,ARI1,,"NADPH-dependent aldehyde reductase, utilizes aromatic and alophatic aldehyde substrates; member of the short-chain dehydrogenase/reductase superfamily",biological_process,oxidoreductase activity,"nucleus, cytoplasm","biological_process, cytoplasm, nucleus, oxidoreductase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,174,11,6.3,no,,,,, P148,25,C1,P148_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL158W,RCK1,,Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations,"meiosis, cell cycle, protein modification process","transferase activity, protein kinase activity",cellular_component,"cell cycle, cellular_component, meiosis, protein kinase activity, protein modification process, transferase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,6,2.7,no,,,,, P148,26,C2,P148_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL159W,,,Putative protein of unknown function; deletion mutant has no detectable phenotype,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,28,8.7,no,,,,, P148,27,C3,P148_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL160W,AIM14,,"Protein with similarity to iron/copper reductases (FRE1-8), possibly involved in iron homeostasis; may interact with ribosomes; null mutant displays elevated frequency of mitochondrial genome loss",biological_process,oxidoreductase activity,"membrane, ribosome, cytoplasm","biological_process, membrane, oxidoreductase activity, ribosome",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,267,12,4.5,no,,,,, P148,28,C4,P148_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL161C,YIP5,,"Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport",biological_process,"protein binding, enzyme regulator activity","cytoplasm, Golgi apparatus","Golgi apparatus, enzyme regulator activity, protein binding, vesicle-mediated transport",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,28,12,no,,,,, P148,29,C5,P148_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL162W,SUT1,,Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression,"transport, transcription, RNA metabolic process",transcription regulator activity,nucleus,"DNA binding, RNA metabolic process, nucleus, transcription, transcription regulator activity, transport",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,5,2.3,no,,,,, P148,30,C6,P148_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL163C,RAD54,XRS1,"DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family","response to stress, chromosome organization, DNA metabolic process","DNA binding, hydrolase activity",nucleus,"DNA binding, DNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, response to stress",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,56,23.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P148,31,C7,P148_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL164C,YRB30,,"RanGTP-binding protein, inhibits RanGAP1 (Rna1p)-mediated GTP hydrolysis of RanGTP (Gsp1p); shares similarity to proteins in other fungi but not in higher eukaryotes",biological_process,"protein binding, enzyme regulator activity","nucleus, cytoplasm","biological_process, cytoplasm, enzyme regulator activity, nucleus, protein binding",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,24,7.4,no,,,,, P148,32,C8,P148_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL165C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CUP2/YGL166W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,12,4.4,no,,,,, P148,33,C9,P148_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL166W,CUP2,ACE1,Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations,"transcription, response to chemical stimulus, protein complex biogenesis, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, response to chemical stimulus, transcription, transcription regulator activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,10,4.6,no,,,,, P148,34,C10,P148_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL167C,PMR1,SSC1;LDB1;BSD1,High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease,"transport, vesicle-mediated transport","transporter activity, hydrolase activity","membrane, endomembrane system, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, endomembrane system, hydrolase activity, membrane, other, protein modification process, transport, transporter activity, vesicle-mediated transport",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,24,9.2,no,,,,, P148,35,C11,P148_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL168W,HUR1,,Protein of unknown function; reported null mutant phenotype of hydroxyurea sensitivity may be due to effects on overlapping PMR1 gene,DNA metabolic process,molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,192,8,4.2,no,,,,, P148,36,C12,P148_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL170C,SPO74,,"Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation",sporulation resulting in formation of a cellular spore,structural molecule activity,"cytoskeleton, microtubule organizing center, cytoplasm","cytoplasm, cytoskeleton, microtubule organizing center, sporulation, structural molecule activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,8,2.7,no,,,,, P148,37,D1,P148_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL173C,KEM1,XRN1;SKI1;SEP1;RAR5;DST2,"Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance","conjugation, ribosome biogenesis, cell cycle, nucleus organization, RNA metabolic process",hydrolase activity,cytoplasm,"RNA metabolic process, cell cycle, conjugation, cytoplasm, hydrolase activity, nuclear organization and biogenesis, organelle organization and biogenesis, other, response to chemical stimulus, ribosome biogenesis",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,2,1,no,,,,, P148,38,D2,P148_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL174W,BUD13,CWC26,"Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern","transport, cytokinesis, cell cycle, RNA metabolic process",molecular_function,nucleus,"RNA metabolic process, anatomical structure morphogenesis, cytokinesis, molecular_function, nucleus, transport",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,50,19.1,no,,,,, P148,39,D3,P148_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL175C,SAE2,COM1,Endonuclease that processes hairpin DNA structures with the MRX complex; involved in meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents,"response to stress, cell cycle, DNA metabolic process","DNA binding, hydrolase activity","nucleus, cytoplasm","DNA binding, DNA metabolic process, cell cycle, cytoplasm, hydrolase activity, meiosis, nucleus, response to stress",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,48,23.9,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P148,40,D4,P148_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL176C,,,Putative protein of unknown function; deletion mutant is viable and has no detectable phenotype,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,23,10.3,no,,,,, P148,41,D5,P148_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL177W,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,250,8,3.2,no,,,,, P148,42,D6,P148_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL179C,TOS3,,"Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome","cellular carbohydrate metabolic process, protein modification process","transferase activity, protein kinase activity",cytoplasm,"carbohydrate metabolic process, cytoplasm, protein kinase activity, protein modification process, transferase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,17,7.1,no,,,,, P148,43,D7,P148_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL180W,ATG1,APG1;CVT10;AUT3,Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p,"vacuole organization, transport, protein modification process, response to stress, cellular membrane organization","transferase activity, protein kinase activity",cytoplasm,"cytoplasm, membrane organization and biogenesis, organelle organization and biogenesis, protein kinase activity, protein modification process, response to stress, transferase activity",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,221,18,8.1,no,,,,, P148,44,D8,P148_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL181W,GTS1,LSR1;FHT1,"Arf3p GTPase Activating Protein (GAP) that localizes to endocytic patches; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms; localizes to nucleus and induces flocculation when overexpressed","transport, transcription, vesicle-mediated transport, sporulation resulting in formation of a cellular spore, cellular lipid metabolic process, cellular component morphogenesis, cell cycle, cellular membrane organization","transcription regulator activity, enzyme regulator activity","nucleus, cell cortex, cytoskeleton, cytoplasm","anatomical structure morphogenesis, cell cortex, cell cycle, cytoplasm, cytoskeleton, enzyme regulator activity, membrane organization and biogenesis, nucleus, other, response to chemical stimulus, sporulation, transcription, transcription regulator activity, transport, vesicle-mediated transport",,,7_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,32,10.1,no,,,,, P148,45,D9,P148_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER101C,AST2,,"Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions",biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,24,11.7,no,,,,, P148,46,D10,P148_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER103W,SSA4,YG107,Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation,"transport, response to stress, protein folding","protein binding, hydrolase activity","nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, protein binding, protein folding, response to stress, transport",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,22,10.9,no,,,,, P148,47,D11,P148_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER106W,MAM1,,"Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle","meiosis, chromosome organization, cell cycle, chromosome segregation",molecular_function,"nucleus, chromosome","cell cycle, chromosome, meiosis, molecular_function, nucleus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,8,3.1,no,,,,, P148,48,D12,P148_D12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P148,49,E1,P148_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER109C,FLO8,YER108C;PHD5,"Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene","pseudohyphal growth, transcription, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, other, pseudohyphal growth, transcription, transcription regulator activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,7,4,no,,,,, P148,50,E2,P148_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER109C,FLO8,YER108C;PHD5,"Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene","pseudohyphal growth, transcription, RNA metabolic process",transcription regulator activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, nucleus, other, pseudohyphal growth, transcription, transcription regulator activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,7,3.5,no,,,,, P148,51,E3,P148_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER110C,KAP123,YRB4,"Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1",transport,transporter activity,"nucleus, membrane, endomembrane system, cytoplasm","cytoplasm, endomembrane system, membrane, nucleus, protein binding, transport, transporter activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,32,13.4,no,,,,, P148,52,E4,P148_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER111C,SWI4,ART1,"DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair","transcription, RNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, RNA metabolic process, cell cycle, nucleus, transcription, transcription regulator activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,16,8.2,no,,,,, P148,53,E5,P148_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER113C,TMN3,,Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn2p; member of Transmembrane Nine family with 9 transmembrane segments; localizes to Golgi; induced by 8-methoxypsoralen plus UVA irradiation,"pseudohyphal growth, cellular homeostasis",molecular_function,"cytoplasmic membrane-bounded vesicle, cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, molecular_function, other, pseudohyphal growth",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,242,12,5,no,,,,, P148,54,E6,P148_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER114C,BOI2,BEB1,"Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain","cell budding, signaling process, cytokinesis",lipid binding,"cellular bud, site of polarized growth","anatomical structure morphogenesis, cell budding, cellular bud, cytokinesis, lipid binding, signal transduction, site of polarized growth",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,13,7.6,no,,,,, P148,55,E7,P148_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER115C,SPR6,,"Protein of unknown function, expressed during sporulation; not required for sporulation, but gene exhibits genetic interactions with other genes required for sporulation",sporulation resulting in formation of a cellular spore,molecular_function,cellular_component,"cellular_component, molecular_function, sporulation",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,30,12.6,no,,,,, P148,56,E8,P148_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER116C,SLX8,,Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by prior attachment of SUMO to the substrate; contains a C-terminal RING domain,"response to stress, chromosome organization, DNA metabolic process, protein modification process",ligase activity,nucleus,"ligase activity, organelle organization and biogenesis, other, protein modification process, response to stress",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,104,39.4,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P148,57,E9,P148_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER117W,RPL23B,YL32;L23B;L17aB,"Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, response to chemical stimulus, ribosome, structural molecule activity, translation",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,14,5.6,no,,,,, P148,58,E10,P148_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER118C,SHO1,SSU81,"Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway","response to stress, pseudohyphal growth",signal transducer activity,"membrane, site of polarized growth, plasma membrane","plasma membrane, pseudohyphal growth, response to stress, signal transducer activity, signal transduction, site of polarized growth",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,292,22,7.5,no,,,,, P148,59,E11,P148_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER119C,AVT6,,Vacuolar aspartate and glutamate exporter; member of a family of seven genes (AVT1-7) related to vesicular GABA-glycine transporters; involved in compartmentalizing acidic amino acids in response to nitrogen starvation,transport,transporter activity,"membrane, vacuole, cytoplasm","cytoplasm, membrane, transport, transporter activity, vacuole",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,4,2.1,no,,,,, P148,60,E12,P148_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER119C-A,,,"Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene SCS2",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,207,11,5.3,no,,,,, P148,61,F1,P148_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER120W,SCS2,,"Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog","transport, transcription, cellular lipid metabolic process, RNA metabolic process","lipid binding, protein binding","nucleus, endomembrane system, cellular bud, membrane, site of polarized growth, endoplasmic reticulum, cytoplasm","RNA metabolic process, cytoplasm, endomembrane system, endoplasmic reticulum, lipid binding, lipid metabolic process, membrane, nucleus, organelle organization and biogenesis, protein binding, transcription, transport",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,18,6.5,no,,,,, P148,62,F2,P148_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER121W,,,Putative protein of unknown function; may be involved in phosphatase regulation and/or generation of precursor metabolites and energy,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,269,25,9.3,no,,,,, P148,63,F3,P148_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER122C,GLO3,,"ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Gcs1p","transport, vesicle organization, vesicle-mediated transport, cellular membrane organization",enzyme regulator activity,"endomembrane system, cytoplasmic membrane-bounded vesicle, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton organization and biogenesis, endomembrane system, enzyme regulator activity, membrane, membrane organization and biogenesis, organelle organization and biogenesis, transport, vesicle-mediated transport",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,31,13.7,no,,,,, P148,64,F4,P148_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER123W,YCK3,CKI3,"Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway","transport, protein modification process, vesicle-mediated transport","transferase activity, protein kinase activity","nucleus, vacuole, membrane, cytoplasm, plasma membrane","cytoplasm, membrane, nucleus, plasma membrane, protein kinase activity, protein modification process, transferase activity, vacuole",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,387,40,10.3,no,,,,, P148,65,F5,P148_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER124C,DSE1,,"Daughter cell-specific protein, may regulate cross-talk between the mating and filamentation pathways; deletion affects cell separation after division and sensitivity to alpha-factor and drugs affecting the cell wall","signaling process, conjugation, cytokinesis, response to chemical stimulus",molecular_function,"cellular bud, site of polarized growth","cellular bud, cytokinesis, molecular_function, site of polarized growth",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,234,5,2.1,no,,,,, P148,66,F6,P148_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER128W,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,20,8.4,no,,,,, P148,67,F7,P148_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER129W,SAK1,PAK1,"Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome","cellular carbohydrate metabolic process, DNA metabolic process, protein modification process","transferase activity, protein kinase activity",cytoplasm,"DNA metabolic process, carbohydrate metabolic process, cytoplasm, protein kinase activity, protein modification process, transferase activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,316,4,1.3,no,,,,, P148,68,F8,P148_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER130C,,,Protein of unknown function,biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,12,5.3,no,,,,, P148,69,F9,P148_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER131W,RPS26B,S26B,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein,"transport, translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,8,4.5,no,,,,, P148,70,F10,P148_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER132C,PMD1,,"Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions",sporulation resulting in formation of a cellular spore,molecular_function,cytoplasm,"cytoplasm, molecular_function, sporulation",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,2,1,no,,,,, P148,71,F11,P148_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER134C,,,Putative protein of unknown function; non-essential gene,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,13,6.4,no,,,,, P148,72,F12,P148_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER135C,,,Dubious open reading frame unlikely to encode a protein; YER135C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P148,73,G1,P148_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER137C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,21,10,no,,,,, P148,74,G2,P148_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER139C,RTR1,,CTD phosphatase; dephosphorylates S5-P in the C-terminal domain of Rpo21p; has a cysteine-rich motif required for function and conserved in eukaryotes; shuttles between the nucleus and cytoplasm,"transcription, protein modification process, RNA metabolic process","phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, nucleus, transcription",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,229,3,1.3,no,,,,, P148,75,G3,P148_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER140W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; genetic interactions suggest a role in folding of ER membrane proteins",protein folding,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,8,4.3,no,,,,, P148,76,G4,P148_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER141W,COX15,,"Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase","cofactor metabolic process, heterocycle metabolic process",oxidoreductase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, heterocycle metabolic process, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,228,28,12.3,no,,,,, P148,77,G5,P148_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER142C,MAG1,MMS5,3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired,"response to stress, DNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, hydrolase activity, nucleus, response to stress",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,20,6.1,no,,,,, P148,78,G6,P148_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER143W,DDI1,VSM1,"DNA damage-inducible v-SNARE binding protein, contains a ubiquitin-associated (UBA) domain, may act as a negative regulator of constitutive exocytosis, may play a role in S-phase checkpoint control","transport, vesicle-mediated transport, cellular protein catabolic process",protein binding,"membrane, plasma membrane","plasma membrane, protein binding, protein catabolic process, vesicle-mediated transport",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,10,3,no,,,,, P148,79,G7,P148_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER145C,FTR1,,High affinity iron permease involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron,"transport, cellular homeostasis",transporter activity,"membrane, plasma membrane","cellular homeostasis, membrane, plasma membrane, transport, transporter activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,14,4.4,no,,,,, P148,80,G8,P148_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER149C,PEA2,PPF2;DFG9,"Coiled-coil polarisome protein required for polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; forms polarisome complex with Bni1p, Bud6p, and Spa2p; localizes to sites of polarized growth","cell budding, signaling process, cytoskeleton organization, cytokinesis, response to chemical stimulus, conjugation, pseudohyphal growth, cellular component morphogenesis, cell cycle",protein binding,"cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, conjugation, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, organelle organization and biogenesis, other, protein binding, pseudohyphal growth, response to chemical stimulus, signal transduction, site of polarized growth",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,20,7.6,no,,,,, P148,81,G9,P148_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER150W,SPI1,,GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p,response to chemical stimulus,molecular_function,cell wall,"cell wall, molecular_function, response to chemical stimulus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,8,4.2,no,,,,, P148,82,G10,P148_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER151C,UBP3,BLM3,Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin,"transport, vesicle-mediated transport, protein modification process","peptidase activity, hydrolase activity",cytoplasm,"cytoplasm, hydrolase activity, other, peptidase activity, protein modification process, response to chemical stimulus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,30,9.2,no,,,,, P148,83,G11,P148_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER152C,,,Protein with 2-aminoadipate transaminase activity; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene,biological_process,transferase activity,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,13,6.1,no,,,,, P148,84,G12,P148_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER153C,PET122,,"Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet494p; located in the mitochondrial inner membrane","mitochondrion organization, translation",translation regulator activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, translation, translation regulator activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,7,3.5,no,,,,, P148,85,H1,P148_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER154W,OXA1,PET1402,"Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals","mitochondrion organization, protein complex biogenesis, cellular membrane organization",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, transporter activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,202,5,2.5,no,,,,, P148,86,H2,P148_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER155C,BEM2,TSL1;SUP9;IPL2,Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence,"fungal-type cell wall organization, cell budding, signaling process, cytoskeleton organization",enzyme regulator activity,"cell cortex, mitochondrion, cellular bud, membrane, site of polarized growth, cytoplasm, plasma membrane","anatomical structure morphogenesis, cell budding, cell wall organization and biogenesis, cytoskeleton organization and biogenesis, enzyme regulator activity, mitochondrion, organelle organization and biogenesis, other, signal transduction",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,13,7.1,no,,,,, P148,87,H3,P148_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P148,88,H4,P148_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER156C,,,"Putative protein of unknown function; interacts with Hsp82p and copurifies with Ipl1p; expression is copper responsive and downregulated in strains deleted for MAC1, a copper-responsive transcription factor; similarity to mammalian MYG1",biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,9,4.7,no,,,,, P148,89,H5,P148_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER158C,,,"Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,191,7,3.7,no,,,,, P148,90,H6,P148_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER161C,SPT2,EXA1;SIN1,"Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins","chromosome organization, transcription, RNA metabolic process",DNA binding,nucleus,"DNA binding, RNA metabolic process, nucleus, organelle organization and biogenesis, transcription",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,16,4.8,no,,,,, P148,91,H7,P148_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER162C,RAD4,,Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein,"response to stress, DNA metabolic process",DNA binding,nucleus,"DNA binding, DNA metabolic process, nucleus, organelle organization and biogenesis, response to stress",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,11,5.4,no,,,,, P148,92,H8,P148_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER163C,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; periodically expressed during the metabolic cycle; weak similarity to bacterial cation transport protein,biological_process,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,186,8,4.3,no,,,,, P148,93,H9,P148_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER164W,CHD1,,"Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes","chromosome organization, transcription, RNA metabolic process","transcription regulator activity, hydrolase activity","nucleus, mitochondrion, cytoplasm","RNA metabolic process, hydrolase activity, mitochondrion, nucleus, organelle organization and biogenesis, transcription, transcription regulator activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,2,1,no,,,,, P148,94,H10,P148_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER166W,DNF1,,"Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase","transport, vesicle-mediated transport, cellular membrane organization","hydrolase activity, transporter activity","mitochondrion, membrane, cytoplasm, plasma membrane","anatomical structure morphogenesis, hydrolase activity, membrane organization and biogenesis, mitochondrion, plasma membrane, transport, transporter activity, vesicle-mediated transport",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,7,3.5,no,,,,, P148,95,H11,P148_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER167W,BCK2,CTR7,"Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations",cell cycle,molecular_function,"nucleus, cytoplasm","cell cycle, cytoplasm, molecular_function, nucleus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,44,13.8,no,,,,, P148,96,H12,P148_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER169W,RPH1,KDM4,JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway,"transcription, protein modification process, response to stress, chromosome organization, DNA metabolic process, RNA metabolic process","transcription regulator activity, oxidoreductase activity, DNA binding",nucleus,"DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, other, oxidoreductase activity, protein modification process, response to stress, transcription, transcription regulator activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,256,50,19.5,no,,,,, P149,1,A1,P149_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER170W,ADK2,PAK3;AKY3,"Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background",other,transferase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, other, transferase activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,190,7,3.7,no,,,,, P149,2,A2,P149_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER173W,RAD24,RS1,"Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein","signaling process, response to stress, meiosis, cell cycle, DNA metabolic process","hydrolase activity, DNA binding","nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, hydrolase activity, meiosis, nucleus, response to stress, signal transduction",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,464,37,8,no,,,,, P149,3,A3,P149_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER174C,GRX4,,Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage,"response to stress, cellular homeostasis, response to chemical stimulus",oxidoreductase activity,nucleus,"cellular homeostasis, nucleus, other, oxidoreductase activity, response to chemical stimulus, response to stress",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,22,7.8,no,,,,, P149,4,A4,P149_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER175C,TMT1,TAM1,"Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle",biological_process,transferase activity,cytoplasm,"biological_process, cytoplasm, transferase activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,24,7.9,no,,,,, P149,5,A5,P149_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER176W,ECM32,MTT1;HEL1,"DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes",translation,"helicase activity, hydrolase activity",other,"helicase activity, other, translation",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,170,19,11.2,no,,,,, P149,6,A6,P149_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER177W,BMH1,APR6,"14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling","signaling process, generation of precursor metabolites and energy, protein modification process, response to stress, cellular carbohydrate metabolic process, sporulation resulting in formation of a cellular spore, pseudohyphal growth, cell cycle","DNA binding, protein binding","nucleus, membrane fraction","DNA binding, carbohydrate metabolic process, cell cycle, cell wall organization and biogenesis, generation of precursor metabolites and energy, nucleus, protein binding, pseudohyphal growth, response to stress, signal transduction, sporulation",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,245,15,6.1,no,,,,, P149,7,A7,P149_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER178W,PDA1,,"E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose",cofactor metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, other, oxidoreductase activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,194,12,6.2,no,,,,, P149,8,A8,P149_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER179W,DMC1,ISC2,Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein,"meiosis, cell cycle, DNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, meiosis, nucleus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,18,9.1,no,,,,, P149,9,A9,P149_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER180C,ISC10,,"Protein required for sporulation, transcript is induced 7.5 hours after induction of meiosis, expected to play significant role in the formation of reproductive cells",sporulation resulting in formation of a cellular spore,molecular_function,cellular_component,"cellular_component, molecular_function, sporulation",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,13,7.4,no,,,,, P149,10,A10,P149_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER181C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative data; extensively overlaps a Ty1 LTR; protein product is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,25,12.7,no,,,,, P149,11,A11,P149_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER182W,FMP10,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,54,17,no,,,,, P149,12,A12,P149_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER183C,FAU1,,"5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis","cofactor metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",ligase activity,"mitochondrion, cytoplasm","aromatic compound metabolic process, cofactor metabolic process, heterocycle metabolic process, ligase activity, mitochondrion",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,180,17,9.4,no,,,,, P149,13,B1,P149_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER184C,,,"Putative zinc cluster protein; deletion confers sensitivity to Calcufluor white, and prevents growth on glycerol or lactate as sole carbon source",biological_process,DNA binding,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,46,16,no,,,,, P149,14,B2,P149_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER185W,PUG1,,Plasma membrane protein with roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins,transport,molecular_function,"membrane, plasma membrane","membrane, molecular_function, plasma membrane, transport",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,184,20,10.9,no,,,,, P149,15,B3,P149_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER186C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,320,38,11.9,no,,,,, P149,16,B4,P149_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER187W,,,Putative protein of unknown function; induced in respiratory-deficient cells,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,16,9.2,no,,,,, P149,17,B5,P149_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR052C-A,,,"Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,193,9,4.7,no,,,,, P149,18,B6,P149_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR052W,FAR3,,"Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far7p, Far8p, Far9p, Far10p, and Far11p; localizes to the endoplasmic reticulum","conjugation, cell cycle, response to chemical stimulus",molecular_function,"endoplasmic reticulum, cytoplasm","cell cycle, conjugation, endoplasmic reticulum, molecular_function, response to chemical stimulus",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,206,8,3.9,no,,,,, P149,19,B7,P149_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR053C,STB2,,Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with Sin3p and Stb1p,"chromosome organization, protein modification process",transcription regulator activity,"nucleus, chromosome","nucleus, organelle organization and biogenesis, protein modification process, transcription regulator activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,13,6.1,no,,,,, P149,20,B8,P149_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR054W,STV1,,"Subunit a of the vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole",cellular homeostasis,"transporter activity, hydrolase activity","membrane, vacuole, cytoplasm, Golgi apparatus","Golgi apparatus, cellular homeostasis, cytoplasm, hydrolase activity, membrane, transporter activity, vacuole",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,274,2,0.7,no,,,,, P149,21,B9,P149_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR055C,BUB2,PAC7,"Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage","signaling process, cell cycle",enzyme regulator activity,"cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoplasm, cytoskeleton, enzyme regulator activity, microtubule organizing center",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,196,48,24.5,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P149,22,B10,P149_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR056C,AAC1,,"Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; Aac1p is a minor isoform while Pet9p is the major ADP/ATP translocator","transport, cofactor metabolic process, heterocycle metabolic process, generation of precursor metabolites and energy, cellular respiration",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,240,24,10,no,,,,, P149,23,B11,P149_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR057C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF AAC1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,239,9,3.8,no,,,,, P149,24,B12,P149_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR058W,FET3,,"Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases","transport, cellular homeostasis, response to chemical stimulus","transporter activity, oxidoreductase activity","membrane, plasma membrane","cellular homeostasis, membrane, oxidoreductase activity, plasma membrane, response to chemical stimulus, transport, transporter activity",,,00_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,23,9.3,no,,,,, P149,25,C1,P149_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR034W,PET191,,Protein required for assembly of cytochrome c oxidase; exists as an oligomer that is integral to the mitochondrial inner membrane and faces the intermembrane space; contains a twin Cx9C motif,"mitochondrion organization, protein complex biogenesis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,278,15,5.4,no,,,,, P149,26,C2,P149_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR039W,,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",biological_process,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,5,2.2,no,,,,, P149,27,C3,P149_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR044C,VPS55,,Late endosomal protein involved in late endosome to vacuole trafficking; functional homolog of human obesity receptor gene-related protein (OB-RGRP),"transport, vesicle-mediated transport",molecular_function,"membrane, cytoplasm","cytoplasm, membrane, molecular_function, transport, vesicle-mediated transport",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,2,1.2,no,,,,, P149,28,C4,P149_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJR066W,TOR1,DRR1,"PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis","ribosome biogenesis, cell cycle, RNA metabolic process, fungal-type cell wall organization, signaling process, transcription, response to stress, meiosis","protein kinase activity, protein binding, transferase activity","nucleus, membrane fraction, vacuole, Golgi apparatus, plasma membrane, endomembrane system, membrane, cytoplasm","Golgi apparatus, cell cycle, cell wall organization and biogenesis, cytoplasm, endomembrane system, meiosis, membrane, membrane fraction, other, plasma membrane, protein binding, protein kinase activity, response to stress, ribosome biogenesis, signal transduction, vacuole",,,00_13,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,23,10.5,no,,,,, P149,29,C5,P149_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL102C,,,Putative protein of unknown function,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,332,0,0,no,,,,, P149,30,C6,P149_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL111W,COX5B,,"Subunit Vb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during anaerobic growth while its isoform Va (Cox5Ap) is expressed during aerobic growth","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,324,8,2.5,no,,,,, P149,31,C7,P149_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL122W,POG1,,Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated,"conjugation, cell cycle, response to chemical stimulus",transcription regulator activity,"nucleus, chromosome","RNA metabolic process, cell cycle, conjugation, nucleus, response to chemical stimulus, signal transduction, transcription, transcription regulator activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,236,2,0.8,no,,,,, P149,32,C8,P149_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL131C,FKH1,,Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching,"transcription, chromosome organization, pseudohyphal growth, cell cycle, DNA metabolic process, RNA metabolic process","transcription regulator activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, RNA metabolic process, cell cycle, nucleus, organelle organization and biogenesis, pseudohyphal growth, transcription, transcription regulator activity",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,209,3,1.4,no,,,,, P149,33,C9,P149_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL136W,OM45,,"Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane",biological_process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, biological_process, cytoplasm, endomembrane system, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,5,2.7,no,,,,, P149,34,C10,P149_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL158W,AIM20,,Putative protein of unknown function; overexpression causes a cell cycle delay or arrest; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; null mutant displays elevated frequency of mitochondrial genome loss,biological_process,molecular_function,"vacuole, cytoplasm","biological_process, cytoplasm, molecular_function, vacuole",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,300,12,4,no,,,,, P149,35,C11,P149_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIR004W,DJP1,PAS22;ICS1,"Cytosolic J-domain-containing protein, required for peroxisomal protein import and involved in peroxisome assembly, homologous to E. coli DnaJ","transport, peroxisome organization",protein binding,cytoplasm,"cytoplasm, organelle organization and biogenesis, protein binding, transport",,,9_2,,,,DIC:cell structure;YFP:Rad52-YFP protein,,258,0,0,no,,,,, P149,36,C12,P149_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL056W,VHR1,,"Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations","cofactor metabolic process, transcription, vitamin metabolic process, heterocycle metabolic process, RNA metabolic process","transcription regulator activity, DNA binding","nucleus, cytoplasm","DNA binding, RNA metabolic process, cofactor metabolic process, cytoplasm, heterocycle metabolic process, nucleus, transcription, transcription regulator activity, vitamin metabolic process",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,334,20,6,no,,,,, P149,37,D1,P149_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL085C,KTR7,,Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family,"fungal-type cell wall organization, cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cell wall organization and biogenesis, protein modification process, transferase activity",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,10,3.8,no,,,,, P149,38,D2,P149_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL094C,LYS12,LYS11;LYS10,"Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate",cellular amino acid and derivative metabolic process,oxidoreductase activity,"mitochondrion, cytoplasm","amino acid and derivative metabolic process, mitochondrion, oxidoreductase activity",,,9_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,262,12,4.6,no,,,,, P149,39,D3,P149_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL047W,SIT4,,Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization,"fungal-type cell wall organization, signaling process, cytoskeleton organization, response to chemical stimulus, response to stress, cell cycle, DNA metabolic process, RNA metabolic process","hydrolase activity, phosphoprotein phosphatase activity","nucleus, cytoplasm","DNA metabolic process, cell cycle, cell wall organization and biogenesis, cytoplasm, cytoskeleton organization and biogenesis, hydrolase activity, nucleus, organelle organization and biogenesis, other, phosphoprotein phosphatase activity, response to chemical stimulus, response to stress, signal transduction",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,10,3.1,no,,,,, P149,40,D4,P149_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL061C,RPS29B,YS29;S36B;S29B;YS29B,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Ap and has similarity to rat S29 and E. coli S14 ribosomal proteins,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,7,4,no,,,,, P149,41,D5,P149_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDL075W,RPL31A,YL28;L34A;L31A;RPL34,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_1,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,220,3,1.4,no,,,,, P149,42,D6,P149_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR477W,SNF1,PAS14;HAF3;GLC2;CCR1;CAT1,"AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis","signaling process, translation, protein modification process, response to stress, cellular carbohydrate metabolic process, pseudohyphal growth","transferase activity, protein kinase activity","nucleus, endomembrane system, vacuole, mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, endomembrane system, mitochondrion, nucleus, other, protein kinase activity, protein modification process, pseudohyphal growth, response to stress, signal transduction, transferase activity, vacuole",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,17,7.1,no,,,,, P149,43,D7,P149_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR500C,RPL37B,YL35;L43;L37B,"Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Ap and to rat L37 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,4_8,,,,DIC:cell structure;YFP:Rad52-YFP protein,,224,17,7.6,no,,,,, P149,44,D8,P149_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR363C,NMD4,,"Protein interacting with Nam7p, may be involved in the nonsense-mediated mRNA decay pathway",RNA metabolic process,molecular_function,cytoplasm,"RNA metabolic process, cytoplasm, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,17,7.3,no,,,,, P149,45,D9,P149_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR364W,GRX8,,Glutaredoxin that employs a dithiol mechanism of catalysis; monomeric; activity is low and null mutation does not affect sensitivity to oxidative stress; GFP-fusion protein localizes to the cytoplasm; expression strongly induced by arsenic,biological_process,oxidoreductase activity,cytoplasm,"biological_process, cytoplasm, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,19,9.4,no,,,,, P149,46,D10,P149_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR365W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious gene YLR364C-A; YLR365W is not an essential gene",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,2,0.6,no,,,,, P149,47,D11,P149_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR366W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR364C-A",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,282,0,0,no,,,,, P149,48,D12,P149_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR367W,RPS22B,rp50;YS22;S24B;S22B,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,16,8.8,no,,,,, P149,49,E1,P149_E1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P149,50,E2,P149_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR368W,MDM30,DSG1,F-box protein; associates with mitochondria and has a role in mitochondrial fusion; stimulates nuclear export of specific mRNAs; promotes ubiquitin-mediated degradation of Gal4p in some strains,"transport, mitochondrion organization, protein modification process, cellular protein catabolic process, cellular membrane organization",ligase activity,"mitochondrion, cytoplasm","ligase activity, membrane organization and biogenesis, mitochondrion, organelle organization and biogenesis, other, protein catabolic process, protein modification process",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,1,0.6,no,,,,, P149,51,E3,P149_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR371W,ROM2,,"GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP","transport, fungal-type cell wall organization, cell budding, signaling process, cytoskeleton organization, response to stress, vesicle-mediated transport, cellular membrane organization","lipid binding, enzyme regulator activity","cellular bud, site of polarized growth","anatomical structure morphogenesis, cell budding, cell wall organization and biogenesis, cellular bud, cytoskeleton organization and biogenesis, enzyme regulator activity, lipid binding, membrane organization and biogenesis, organelle organization and biogenesis, response to stress, signal transduction, site of polarized growth, transport, vesicle-mediated transport",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,28,12.2,no,,,,, P149,52,E4,P149_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR372W,SUR4,APA1;VBM1;SRE1;ELO3,"Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis","transport, vesicle-mediated transport, cellular lipid metabolic process",transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, transferase activity, transport, vesicle-mediated transport",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,2,0.6,no,,,,, P149,53,E5,P149_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR373C,VID22,,"Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles",cellular protein catabolic process,molecular_function,"membrane, plasma membrane","membrane, molecular_function, plasma membrane, protein catabolic process",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,18,8.3,no,,,,, P149,54,E6,P149_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR374C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF STP3/YLR375W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,343,0,0,no,,,,, P149,55,E7,P149_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR375W,STP3,,"Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids",biological_process,DNA binding,nucleus,"biological_process, molecular_function, nucleus",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,238,22,9.2,no,,,,, P149,56,E8,P149_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR376C,PSY3,,"Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair; deletion results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C","response to stress, DNA metabolic process",molecular_function,"nucleus, cytoplasm","DNA metabolic process, cytoplasm, molecular_function, nucleus, response to stress",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,5,1.6,no,,,,, P149,57,E9,P149_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR377C,FBP1,ACN8,"Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; interacts with Vid30p",cellular carbohydrate metabolic process,hydrolase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, hydrolase activity, other",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,203,20,9.9,no,,,,, P149,58,E10,P149_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR380W,CSR1,SFH2,Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance,"transport, fungal-type cell wall organization, cellular lipid metabolic process, cellular protein catabolic process",transporter activity,"membrane fraction, mitochondrion, cytoplasm","cell wall organization and biogenesis, cytoplasm, lipid metabolic process, membrane fraction, mitochondrion, protein catabolic process, transport, transporter activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,18,8.5,no,,,,, P149,59,E11,P149_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR381W,CTF3,CHL3,Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules,"chromosome organization, cell cycle, chromosome segregation",protein binding,"nucleus, chromosome","chromosome, nucleus, other, protein binding",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,1,0.5,no,,,,, P149,60,E12,P149_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR384C,IKI3,KTI7;TOT1;ELP1,"Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)","transcription, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, nucleus, other, transcription",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,188,2,1.1,no,,,,, P149,61,F1,P149_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR385C,SWC7,AWS1,"Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin",chromosome organization,molecular_function,"nucleus, chromosome","molecular_function, nucleus, organelle organization and biogenesis",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,7,3.6,no,,,,, P149,62,F2,P149_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR386W,VAC14,,"Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p",cellular lipid metabolic process,protein binding,"membrane, vacuole, cytoplasm","cytoplasm, enzyme regulator activity, lipid metabolic process, membrane, organelle organization and biogenesis, vacuole",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,171,13,7.6,no,,,,, P149,63,F3,P149_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR387C,REH1,,"Cytoplasmic 60S subunit biogenesis factor, associates with pre-60S particles; similar to Rei1p and shares partially redundant function in cytoplasmic 60S subunit maturation; contains dispersed C2H2 zinc finger domains",ribosome biogenesis,molecular_function,"ribosome, cytoplasm","biological_process, cytoplasm, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,214,1,0.5,no,,,,, P149,64,F4,P149_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR388W,RPS29A,YS29;S36A;S29A;YS29A,Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins,translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,269,0,0,no,,,,, P149,65,F5,P149_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR389C,STE23,,"Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; expressed in both haploids and diploids; member of the insulin-degrading enzyme family",other,"peptidase activity, hydrolase activity",membrane fraction,"hydrolase activity, membrane, other, peptidase activity, protein modification process",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,14,5.6,no,,,,, P149,66,F6,P149_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR390W,ECM19,,"Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",fungal-type cell wall organization,molecular_function,"mitochondrion, cytoplasm","cell wall organization and biogenesis, mitochondrion, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,199,5,2.5,no,,,,, P149,67,F7,P149_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR344W,RPL26A,YL33;L33A;L26A,"Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA",translation,"RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, ribosome, structural molecule activity, translation",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,270,4,1.5,no,,,,, P149,68,F8,P149_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR345W,,,"Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metabolism of fructoso-2,6-bisphosphate; mRNA expression is repressed by the Rfx1p-Tup1p-Ssn6p repressor complex; YLR345W is not an essential gene","cellular carbohydrate metabolic process, generation of precursor metabolites and energy",transferase activity,cytoplasm,"carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, transferase activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,281,0,0,no,,,,, P149,69,F9,P149_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR348C,DIC1,,"Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix",transport,transporter activity,"mitochondrial envelope, mitochondrion, cytoplasm","mitochondrial envelope, mitochondrion, transport, transporter activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,23,12.3,no,,,,, P149,70,F10,P149_F10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR349W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF DIC1/YLR348C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,182,18,9.9,no,,,,, P149,71,F11,P149_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR350W,ORM2,,"Evolutionarily conserved protein, similar to Orm1p, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control","response to stress, cellular lipid metabolic process, response to chemical stimulus",molecular_function,"membrane, endomembrane system, endoplasmic reticulum, cytoplasm","endoplasmic reticulum, molecular_function, response to chemical stimulus, response to stress",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,3,1.5,no,,,,, P149,72,F12,P149_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR351C,NIT3,,"Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member",biological_process,hydrolase activity,"mitochondrion, cytoplasm","biological_process, cytoplasm, hydrolase activity, mitochondrion",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,1,0.5,no,,,,, P149,73,G1,P149_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR352W,,,Putative protein of unknown function with similarity to F-box proteins; interacts with Skp1p and Cdc53p; YLR352W is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,14,4.3,no,,,,, P149,74,G2,P149_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR353W,BUD8,,"Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole","cytokinesis, pseudohyphal growth, cell cycle",molecular_function,"cellular bud, membrane, site of polarized growth, plasma membrane","anatomical structure morphogenesis, cellular bud, cytokinesis, molecular_function, other, pseudohyphal growth, site of polarized growth",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,187,2,1.1,no,,,,, P149,75,G3,P149_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR354C,TAL1,,"Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate","cofactor metabolic process, cellular carbohydrate metabolic process",transferase activity,cytoplasm,"carbohydrate metabolic process, cofactor metabolic process, cytoplasm, transferase activity, vitamin metabolic process",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,44,13.5,no,,,,, P149,76,G4,P149_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR356W,ATG33,,"Mitochondrial mitophagy-specific protein; required primarily for mitophagy induced at the post-log phase; not required for other types of selective autophagy or macroautophagy; conserved within fungi, but not in higher eukaryotes",other,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,20,6.2,no,,,,, P149,77,G5,P149_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR357W,RSC2,,Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance,"transcription, chromosome segregation, response to stress, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, RNA metabolic process, cell cycle, hydrolase activity, nucleus, organelle organization and biogenesis, other, response to stress, transcription",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,284,2,0.7,no,,,,, P149,78,G6,P149_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR360W,VPS38,VPL17,Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) sorting; binds Vps30p and Vps34p to promote production of phosphatidylinositol 3-phosphate (PtdIns3P) which stimulates kinase activity,"transport, vesicle-mediated transport, cellular protein catabolic process",molecular_function,cytoplasm,"cytoplasm, molecular_function, protein catabolic process, transport, vesicle-mediated transport",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,,178,37,20.8,no,,,,, P149,79,G7,P149_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR362W,STE11,,"Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p","signaling process, transposition, response to chemical stimulus, protein modification process, response to stress, conjugation, pseudohyphal growth","transferase activity, protein kinase activity, signal transducer activity, protein binding",cytoplasm,"conjugation, cytoplasm, other, protein binding, protein kinase activity, protein modification process, pseudohyphal growth, response to chemical stimulus, response to stress, signal transducer activity, signal transduction, transferase activity",,,12_5,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,ND,ND,,no,,,,, P149,80,G8,P149_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAL024C,LTE1,MSI2,Protein similar to GDP/GTP exchange factors but without detectable GEF activity; required for asymmetric localization of Bfa1p at daughter-directed spindle pole bodies and for mitotic exit at low temperatures,"transport, vesicle-mediated transport, signaling process, cell cycle",enzyme regulator activity,cellular bud,"cell cycle, cellular bud, enzyme regulator activity, response to chemical stimulus, vesicle-mediated transport",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,24,7.7,no,,,,, P149,81,G9,P149_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR299W,MAL32,MALS;MAL3S,"Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL3 complex locus; functional in genomic reference strain S288C; hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose",cellular carbohydrate metabolic process,hydrolase activity,membrane fraction,"carbohydrate metabolic process, cellular_component, hydrolase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,12,3.7,no,,,,, P149,82,G10,P149_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR107W,AAD3,,Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role,other,oxidoreductase activity,cellular_component,"cellular_component, other, oxidoreductase activity, response to chemical stimulus",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,304,22,7.2,no,,,,, P149,83,G11,P149_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR242W,AMD2,,Putative amidase,biological_process,hydrolase activity,cellular_component,"biological_process, cellular_component, hydrolase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,260,2,0.8,no,,,,, P149,84,G12,P149_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR326C,YSP2,,Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification,other,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, other",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,264,4,1.5,no,,,,, P149,85,H1,P149_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR417C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RPL12B/YDR418W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,336,20,6,no,,,,, P149,86,H2,P149_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR444W,,,Putative protein of unknown function,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,314,18,5.7,no,,,,, P149,87,H3,P149_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P149,88,H4,P149_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR461W,MFA1,,"Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2","signaling process, conjugation, response to chemical stimulus",protein binding,extracellular region,"conjugation, extracellular region, other, protein binding, response to chemical stimulus, signal transduction",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,213,20,9.4,no,,,,, P149,89,H5,P149_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR493W,MZM1,AIM8;FMP36,Mitochondrial matrix protein with a role in maintaining the labile mitochondrial zinc pool; null mutant has a respiratory growth defect and an elevated frequency of mitochondrial genome loss; overexpression causes cell cycle delay or arrest,cellular homeostasis,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,195,21,10.8,no,,,,, P149,90,H6,P149_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR500C,RPL37B,YL35;L43;L37B,"Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Ap and to rat L37 ribosomal protein",translation,structural molecule activity,"ribosome, cytoplasm","cytoplasm, ribosome, structural molecule activity, translation",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,326,20,6.1,no,,,,, P149,91,H7,P149_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR502C,SAM2,ETH2,"S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)","cellular amino acid and derivative metabolic process, cellular aromatic compound metabolic process",transferase activity,cellular_component,"amino acid and derivative metabolic process, aromatic compound metabolic process, cellular_component, heterocycle metabolic process, transferase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,226,3,1.3,no,,,,, P149,92,H8,P149_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR506C,,,Possible membrane-localized protein,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,2,0.6,no,,,,, P149,93,H9,P149_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR512C,EMI1,,"Non-essential protein required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation; contains twin cysteine-x9-cysteine motifs","sporulation resulting in formation of a cellular spore, mitochondrion organization, transcription, protein complex biogenesis, RNA metabolic process",molecular_function,cellular_component,"RNA metabolic process, cellular_component, molecular_function, sporulation, transcription",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,1,0.6,no,,,,, P149,94,H10,P149_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR515W,SLF1,SRO99,RNA binding protein that associates with polysomes; proposed to be involved in regulating mRNA translation; involved in the copper-dependent mineralization of copper sulfide complexes on cell surface in cells cultured in copper salts,"translation, cellular homeostasis",RNA binding,cytoplasm,"RNA binding, cellular homeostasis, cytoplasm, other, translation",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,248,12,4.8,no,,,,, P149,95,H11,P149_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER089C,PTC2,,Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; role in DNA checkpoint inactivation,"response to stress, signaling process, cell cycle, response to chemical stimulus, protein modification process","phosphoprotein phosphatase activity, hydrolase activity","nucleus, cytoplasm","cell cycle, cytoplasm, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process, response to chemical stimulus, response to stress, signal transduction",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,312,4,1.3,no,,,,, P149,96,H12,P149_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL001W,DEG1,HRM3;PUS3,"tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm; non-essential for viability",RNA metabolic process,isomerase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, isomerase activity, nucleus",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,286,10,3.5,no,,,,, P150,1,A1,P150_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL003C,MSH4,,"Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein","meiosis, cell cycle, DNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, meiosis, nucleus",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,175,6,3.4,no,,,,, P150,2,A2,P150_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL004W,VTC2,PHM1,"Subunit of the vacuolar transporter chaperone (VTC) complex involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion","vacuole organization, transport, cellular membrane organization",molecular_function,"vacuole, membrane, endoplasmic reticulum, cytoplasm","cytoplasm, endoplasmic reticulum, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, other, transport, vacuole",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,22,10.4,no,,,,, P150,3,A3,P150_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL007W,BLM10,YFL006W,"Proteasome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200",protein complex biogenesis,molecular_function,nucleus,"enzyme regulator activity, nucleus, other, protein catabolic process",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,269,8,3,no,,,,, P150,4,A4,P150_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL010C,WWM1,,"WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1",biological_process,molecular_function,"nucleus, mitochondrion, cytoplasm","biological_process, cytoplasm, mitochondrion, molecular_function, nucleus",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,173,19,11,no,,,,, P150,5,A5,P150_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL010W-A,AUA1,YFL011W-A,"Protein required for the negative regulation by ammonia of Gap1p, which is a general amino acid permease",transport,molecular_function,cellular_component,"cellular_component, molecular_function, transport",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,230,19,8.3,no,,,,, P150,6,A6,P150_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL012W,,,Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,217,10,4.6,no,,,,, P150,7,A7,P150_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL013C,IES1,,Subunit of the INO80 chromatin remodeling complex,chromosome organization,molecular_function,"nucleus, chromosome","molecular_function, nucleus, organelle organization and biogenesis",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,225,20,8.9,no,,,,, P150,8,A8,P150_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL033C,RIM15,TAK1,"Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase","response to chemical stimulus, protein modification process, response to stress, meiosis, cell cycle","transferase activity, protein kinase activity","nucleus, cytoplasm","cell cycle, cytoplasm, meiosis, nucleus, protein kinase activity, protein modification process, response to chemical stimulus, response to stress, transferase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,175,20,11.4,no,,,,, P150,9,A9,P150_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR122C-A,,,"Dubious open reading frame unlikely to encode a functional protein, similar to YLR334C and YOL106W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,179,3,1.7,no,,,,, P150,10,A10,P150_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR162W,TIF4631,eiF4G1,"Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit","translation, ribosome biogenesis",RNA binding,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, ribosome biogenesis, translation, translation regulator activity",,,00_17,,,rg notes: FAILED Q.C DIPLOID; consortium notes: Failed QC,DIC:cell structure;YFP:Rad52-YFP protein,,316,18,5.7,no,,,,, P150,11,A11,P150_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR252W,GCN5,AAS104;KAT2;SWI9;ADA4,"Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily","transcription, protein modification process, response to stress, chromosome organization, RNA metabolic process","transcription regulator activity, transferase activity, protein binding","nucleus, chromosome","chromosome, nucleus, organelle organization and biogenesis, protein binding, protein modification process, transcription regulator activity, transferase activity",,,00_17,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,278,0,0,no,,,,, P150,12,A12,P150_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR254W,ENO1,enolase;HSP48,"Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose","vacuole organization, generation of precursor metabolites and energy, cellular carbohydrate metabolic process, cellular membrane organization",lyase activity,"membrane fraction, vacuole, mitochondrion, cytoplasm","carbohydrate metabolic process, cytoplasm, generation of precursor metabolites and energy, lyase activity, membrane organization and biogenesis, mitochondrion, organelle organization and biogenesis, vacuole",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,images not available,207,2,1,no,,,,, P150,13,B1,P150_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR255C,COQ6,,"Putative flavin-dependent monooxygenase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes",cofactor metabolic process,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,00_17,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,199,3,1.5,no,,,,, P150,14,B2,P150_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR257C,MTM1,,"Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, other, transport, transporter activity",,,00_17,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,219,6,2.7,no,,,,, P150,15,B3,P150_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR258C,RAD2,,"Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein","response to stress, transcription, DNA metabolic process, RNA metabolic process",hydrolase activity,nucleus,"DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, response to stress, transcription",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,310,2,0.6,no,,,,, P150,16,B4,P150_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR271W,SLH1,,"Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses",translation,"helicase activity, hydrolase activity",cytoplasm,"cytoplasm, helicase activity, translation",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,302,16,5.3,no,,,,, P150,17,B5,P150_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR272C,,,,,,,,,,00_17,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,190,21,11.1,no,,,,, P150,18,B6,P150_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR273C,,,Putative protein of unknown function; expression downregulated by treatment with 8-methoxypsoralen plus UVA irradiation; YGR273C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,3,1.4,no,,,,, P150,19,B7,P150_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR276C,RNH70,RNA82;REX1,3'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts,"ribosome biogenesis, RNA metabolic process",hydrolase activity,nucleus,"RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,233,2,0.9,no,,,,, P150,20,B8,P150_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR289C,MAL11,MALT;AGT1,Inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; broad substrate specificity that includes maltotriose; required for isomaltose utilization,"transport, cellular carbohydrate metabolic process",transporter activity,"membrane, plasma membrane","plasma membrane, transport, transporter activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,177,2,1.1,no,,,,, P150,21,B9,P150_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR291C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,212,5,2.4,no,,,,, P150,22,B10,P150_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR292W,MAL12,MALS,"Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus; hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose",cellular carbohydrate metabolic process,hydrolase activity,membrane fraction,"carbohydrate metabolic process, cellular_component, hydrolase activity",,,00_17,,,,DIC:cell structure;YFP:Rad52-YFP protein,,208,4,1.9,no,,,,, P150,23,B11,P150_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR020W,GAL1,,"Galactokinase, phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p","cellular carbohydrate metabolic process, transcription, response to chemical stimulus, RNA metabolic process",transferase activity,cytoplasm,"RNA metabolic process, carbohydrate metabolic process, cytoplasm, response to chemical stimulus, transcription, transferase activity, transport",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,329,0,0,no,,,,, P150,24,B12,P150_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR074W,,YBR075W,Putative metalloprotease,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,4,1.4,no,,,,, P150,25,C1,P150_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR417C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RPL12B/YDR418W",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,204,5,2.5,no,,,,, P150,26,C2,P150_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL033C,RIM15,TAK1,"Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase","response to chemical stimulus, protein modification process, response to stress, meiosis, cell cycle","transferase activity, protein kinase activity","nucleus, cytoplasm","cell cycle, cytoplasm, meiosis, nucleus, protein kinase activity, protein modification process, response to chemical stimulus, response to stress, transferase activity",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,286,18,6.3,no,,,,, P150,27,C3,P150_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL063W,,,"Dubious open reading frame, based on available experimental and comparative sequence data",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,172,12,7,no,,,,, P150,28,C4,P150_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL103C,GSM1,,"Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis",generation of precursor metabolites and energy,DNA binding,cellular_component,"DNA binding, cellular_component, generation of precursor metabolites and energy",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,322,16,5,no,,,,, P150,29,C5,P150_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML073C,RPL6A,rp18;YL16;L6A;L17A;YL16A,"N-terminally acetylated protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA","translation, ribosome biogenesis","RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, organelle organization and biogenesis, ribosome, ribosome biogenesis, structural molecule activity, translation",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,1,0.5,no,,,,, P150,30,C6,P150_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL011C,,,Putative protein of unknown function; YNL011C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,328,0,0,no,,,,, P150,31,C7,P150_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL014W,HEF3,ZRG7,Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells,translation,"RNA binding, hydrolase activity","ribosome, cytoplasm","cytoplasm, hydrolase activity, ribosome, translation, translation regulator activity",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,201,1,0.5,no,,,,, P150,32,C8,P150_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL047C,SLM2,LIT1,"Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex","signaling process, cytoskeleton organization",lipid binding,"membrane, plasma membrane","cytoskeleton organization and biogenesis, lipid binding, organelle organization and biogenesis, other, plasma membrane, signal transduction",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,291,0,0,no,,,,, P150,33,C9,P150_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL053W,MSG5,,"Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p","transport, fungal-type cell wall organization, signaling process, response to chemical stimulus, protein modification process, conjugation","hydrolase activity, phosphoprotein phosphatase activity","nucleus, cytoplasm","conjugation, cytoplasm, hydrolase activity, nucleus, phosphoprotein phosphatase activity, protein modification process, response to chemical stimulus, signal transduction",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,215,1,0.5,no,,,,, P150,34,C10,P150_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL059C,ARP5,,"Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes",chromosome organization,"helicase activity, hydrolase activity","nucleus, chromosome","helicase activity, hydrolase activity, nucleus, organelle organization and biogenesis",,,00_18,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,173,2,1.2,no,,,,, P150,35,C11,P150_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL069C,RPL16B,rp23;YL15;L21B;L16B;RP23,"N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p",translation,"RNA binding, structural molecule activity","ribosome, cytoplasm","RNA binding, cytoplasm, ribosome, structural molecule activity, translation",,,00_18,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,311,0,0,no,,,,, P150,36,C12,P150_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL086W,,,Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to endosomes,biological_process,molecular_function,cytoplasm,"biological_process, cytoplasm, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,198,4,2,no,,,,, P150,37,D1,P150_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL089C,,,Dubious open reading frame unlikely to encode a functional protein; almost completely overlaps YNL090W/RHO2 which encodes a small GTPase of the Rho/Rac subfamily of Ras-like proteins,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,276,10,3.6,no,,,,, P150,38,D2,P150_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL096C,RPS7B,rp30;S7B,"Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Ap; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins","translation, ribosome biogenesis",structural molecule activity,"ribosome, cytoplasm","cytoplasm, nucleolus, nucleus, ribosome, structural molecule activity, translation",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,288,0,0,no,,,,, P150,39,D3,P150_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL109W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YNL108C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,227,6,2.6,no,,,,, P150,40,D4,P150_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL111C,CYB5,,"Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation",other,other,"membrane, membrane fraction, endomembrane system, endoplasmic reticulum, cytoplasm","cytoplasm, endomembrane system, endoplasmic reticulum, lipid metabolic process, membrane, membrane fraction, other",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,15,7.9,no,,,,, P150,41,D5,P150_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL147W,LSM7,,"Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA","ribosome biogenesis, RNA metabolic process",RNA binding,"nucleus, nucleolus, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, nucleolus, nucleus, other",,,00_18,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,370,0,0,no,,,,, P150,42,D6,P150_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL268W,LYP1,,"Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids",transport,transporter activity,"membrane, mitochondrion, plasma membrane, cytoplasm","mitochondrion, plasma membrane, transport, transporter activity",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,200,5,2.5,no,,,,, P150,43,D7,P150_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL284C,MRPL10,YmL10;YmL18;MRPL18,Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,216,5,2.3,no,,,,, P150,44,D8,P150_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL315C,ATP11,,"Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase","mitochondrion organization, protein complex biogenesis",protein binding,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, organelle organization and biogenesis, protein binding",,,00_18,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,172,3,1.7,no,,,,, P150,45,D9,P150_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNR033W,ABZ1,,"Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB; required for the synthesis of para-aminobenzoic acid, an important intermediate for folate and ubiquinone Q biosynthesis","cofactor metabolic process, cellular amino acid and derivative metabolic process, vitamin metabolic process, heterocycle metabolic process, cellular aromatic compound metabolic process",transferase activity,cytoplasm,"aromatic compound metabolic process, cofactor metabolic process, cytoplasm, heterocycle metabolic process, ligase activity",,,00_18,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,219,3,1.4,no,,,,, P150,46,D10,P150_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL148C,SPT20,ADA5,"Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex","response to stress, chromosome organization, response to chemical stimulus, protein modification process, RNA metabolic process","transcription regulator activity, protein binding",nucleus,"RNA metabolic process, nucleus, organelle organization and biogenesis, protein binding, protein modification process, response to chemical stimulus, response to stress, signal transduction, transcription regulator activity",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,18,8.2,no,,,,, P150,47,D11,P150_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL151W,GRE2,,"3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway",other,oxidoreductase activity,"nucleus, cytoplasm","cytoplasm, lipid metabolic process, nucleus, other, oxidoreductase activity, response to stress",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,220,5,2.3,no,,,,, P150,48,D12,P150_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL152W,FRE7,,Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels,transport,oxidoreductase activity,"membrane, plasma membrane","oxidoreductase activity, plasma membrane, transport",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,185,3,1.6,no,,,,, P150,49,E1,P150_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL158C,AIM44,,Protein of unknown function; GFP-fusion protein localizes to the bud neck; transcription is regulated by Swi5p; null mutant displays elevated frequency of mitochondrial genome loss,biological_process,molecular_function,"cellular bud, site of polarized growth","biological_process, cellular bud, molecular_function, site of polarized growth",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,181,3,1.7,no,,,,, P150,50,E2,P150_E2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,51,E3,P150_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL183W-A,RTC6,GON5,"Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome; null mutation suppresses cdc13-1 temperature sensitivity","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,00_18,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,211,9,4.3,no,,,,, P150,52,E4,P150_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL194W,DDC1,,"DNA damage checkpoint protein, part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate","signaling process, response to stress, meiosis, cell cycle, DNA metabolic process",molecular_function,"nucleus, chromosome","DNA metabolic process, cell cycle, chromosome, meiosis, molecular_function, nucleus, response to stress, signal transduction",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,168,28,16.7,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P150,53,E5,P150_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR011C,,,"Putative transporter, member of the mitochondrial carrier family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,318,24,7.5,no,,,,, P150,54,E6,P150_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR021C,AGC1,,"Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis",transport,transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, other, transport, transporter activity",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,197,9,4.6,no,,,,, P150,55,E7,P150_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR083W,MDM36,,Mitochondrial protein required for normal mitochondrial morphology and inheritance; proposed involvement in the formation of Dnm1p and Num1p-containing cortical anchor complexes that promote mitochondrial fission,mitochondrion organization,molecular_function,"mitochondrion, cytoplasm","cellular_component, molecular_function, organelle organization and biogenesis",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,189,10,5.3,no,,,,, P150,56,E8,P150_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR091C,,,"Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YPR091C is not an essential gene",biological_process,molecular_function,"ribosome, endoplasmic reticulum, cytoplasm","biological_process, endoplasmic reticulum, molecular_function, ribosome",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,219,3,1.4,no,,,,, P150,57,E9,P150_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR118W,MRI1,,5'-methylthioribose-1-phosphate isomerase; catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway,cellular amino acid and derivative metabolic process,isomerase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, isomerase activity, nucleus",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,218,13,6,no,,,,, P150,58,E10,P150_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR133W-A,TOM5,MOM8A,Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore,"transport, mitochondrion organization",transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,00_18,,,rg notes: rg growth ok ; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,326,8,2.5,no,,,,, P150,59,E11,P150_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR151C,SUE1,,Mitochondrial protein required for degradation of unstable forms of cytochrome c,other,molecular_function,"mitochondrial envelope, mitochondrion, cytoplasm","mitochondrial envelope, molecular_function, protein catabolic process",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,338,30,8.9,no,,,,, P150,60,E12,P150_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR074C,,,"Protein with homology to human PDCD5, which is involved in programmed cell death; N-terminal region forms a conserved triple-helix bundle structure; overexpression promotes H2O2-induced apoptosis; YMR074C is not an essential gene",other,molecular_function,"nucleus, cytoplasm","biological_process, cytoplasm, molecular_function, nucleus",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,205,4,2,no,,,,, P150,61,F1,P150_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR118C,,,Protein of unknown function with similarity to succinate dehydrogenase cytochrome b subunit; YMR118C is not an essential gene,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,266,26,9.8,no,,,,, P150,62,F2,P150_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL153C,,,,,,,,,,00_18,,,,DIC:cell structure;YFP:Rad52-YFP protein,,330,6,1.8,no,,,,, P150,63,F3,P150_F3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,64,F4,P150_F4,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,65,F5,P150_F5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,66,F6,P150_F6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,67,F7,P150_F7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,68,F8,P150_F8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,69,F9,P150_F9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,70,F10,P150_F10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,71,F11,P150_F11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,72,F12,P150_F12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,73,G1,P150_G1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,74,G2,P150_G2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,75,G3,P150_G3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,76,G4,P150_G4,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,77,G5,P150_G5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,78,G6,P150_G6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,79,G7,P150_G7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,80,G8,P150_G8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,81,G9,P150_G9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,82,G10,P150_G10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,83,G11,P150_G11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,84,G12,P150_G12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,85,H1,P150_H1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,86,H2,P150_H2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,87,H3,P150_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,88,H4,P150_H4,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,89,H5,P150_H5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,90,H6,P150_H6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,91,H7,P150_H7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,92,H8,P150_H8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,93,H9,P150_H9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,94,H10,P150_H10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,95,H11,P150_H11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P150,96,H12,P150_H12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P170,1,A1,P170_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER017C,AFG3,YTA10,"Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes","transport, mitochondrion organization, protein complex biogenesis","peptidase activity, hydrolase activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, peptidase activity, protein modification process, transport",,,05_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,194,20,10.3,no,,,,, P170,2,A2,P170_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER050C,RSM18,,"Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S18 ribosomal protein","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,05_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,262,24,9.2,no,,,,, P170,3,A3,P170_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL039C,CYC3,CCHL;cytochrome c heme lyase,"Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)","protein modification process, protein complex biogenesis",lyase activity,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, lyase activity, mitochondrial envelope, mitochondrion, protein modification process",,,01_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,185,10,5.4,no,,,,, P170,4,A4,P170_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4739,YAL027W,SAW1,,Protein involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during double-strand break repair via single-strand annealing; green fluorescent protein (GFP)-fusion protein localizes to the nucleus,"response to stress, DNA metabolic process",molecular_function,nucleus,"biological_process, molecular_function, nucleus",,,01_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,237,9,3.8,no,,,,, P170,5,A5,P170_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML061C,PIF1,TST1,DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA,"mitochondrion organization, chromosome organization, DNA metabolic process","helicase activity, hydrolase activity, enzyme regulator activity","nucleus, mitochondrion, cytoplasm","DNA metabolic process, helicase activity, mitochondrion, nucleus, organelle organization and biogenesis",,,13_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,200,11,5.5,no,,,,, P170,6,A6,P170_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR015C,ERG5,CYP61,"C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs",other,oxidoreductase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, lipid metabolic process, oxidoreductase activity",,,13_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,227,12,5.3,no,,,,, P170,7,A7,P170_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR021C,MAC1,CUA1,Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport,"transcription, cellular homeostasis, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, cellular homeostasis, nucleus, protein catabolic process, response to chemical stimulus, transcription, transcription regulator activity",,,13_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,292,5,1.7,no,,,,, P170,8,A8,P170_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR035W,IMP2,,"Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p","transport, mitochondrion organization","peptidase activity, hydrolase activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, peptidase activity, protein modification process, transport",,,13_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,213,21,9.9,no,,,,, P170,9,A9,P170_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR151W,YIM2,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 5% of ORF overlaps the verified gene IMP1",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,13_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,261,10,3.8,no,,,,, P170,10,A10,P170_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR150C,IMP1,PET-TS2858,"Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p","transport, mitochondrion organization","peptidase activity, hydrolase activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, peptidase activity, protein modification process, transport",,,13_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,275,32,11.6,no,,,,, P170,11,A11,P170_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR152W,YIM1,,"Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",response to stress,molecular_function,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, molecular_function, response to stress",,,13_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,232,11,4.7,no,,,,, P170,12,A12,P170_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR193W,MRPL24,YmL14;YmL24;MRPL14,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,13_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,336,8,2.4,no,,,,, P170,13,B1,P170_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR228W,MTF1,,"Mitochondrial RNA polymerase specificity factor with structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors, interacts with mitochondrial core polymerase Rpo41p","mitochondrion organization, transcription, protein complex biogenesis, RNA metabolic process",transferase activity,"mitochondrion, mitochondrial envelope, cytoplasm","RNA metabolic process, cytoplasm, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transcription, transcription regulator activity, transferase activity",,,13_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,336,18,5.4,no,,,,, P170,14,B2,P170_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR256C,COX7,,"Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,224,17,7.6,no,,,,, P170,15,B3,P170_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR257C,PET111,,Mitochondrial translational activator specific for the COX2 mRNA; located in the mitochondrial inner membrane,"mitochondrion organization, translation",translation regulator activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, translation, translation regulator activity",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,195,11,5.6,no,,,,, P170,16,B4,P170_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR267W,PPA2,IPP2,"Mitochondrial inorganic pyrophosphatase, required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate","generation of precursor metabolites and energy, cellular respiration",hydrolase activity,"mitochondrion, cytoplasm","cellular respiration, generation of precursor metabolites and energy, hydrolase activity, mitochondrion",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,338,32,9.5,no,,,,, P170,17,B5,P170_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR282C,AEP2,ATP13,"Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader","mitochondrion organization, translation",molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, translation",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,338,16,4.7,no,,,,, P170,18,B6,P170_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR286W,MRPL33,YmL33,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,257,12,4.7,no,,,,, P170,19,B7,P170_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR287C,DSS1,MSU1,"3'-5' exoribonuclease, component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs",RNA metabolic process,hydrolase activity,"mitochondrion, cytoplasm","RNA metabolic process, cytoplasm, hydrolase activity, mitochondrion",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,267,14,5.2,no,,,,, P170,20,B8,P170_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR293C,HER2,RRG6;GEP6;LRC6,Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase,"cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy, cellular respiration, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","cellular respiration, generation of precursor metabolites and energy, hydrolase activity, mitochondrion, organelle organization and biogenesis",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,270,8,3,no,,,,, P170,21,B9,P170_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHL038C,CBP2,,"Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene",RNA metabolic process,RNA binding,"mitochondrion, cytoplasm","RNA metabolic process, mitochondrion, other",,,08_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,250,5,2,no,,,,, P170,22,B10,P170_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR011W,DIA4,,"Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth","mitochondrion organization, translation, cellular amino acid and derivative metabolic process, generation of precursor metabolites and energy, cellular respiration, pseudohyphal growth, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, ligase activity, mitochondrion, other, pseudohyphal growth, translation",,,08_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,176,6,3.4,no,,,,, P170,23,B11,P170_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL271W,ATP15,ATPEPSILON,"Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated","transport, heterocycle metabolic process","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,16_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,217,10,4.6,no,,,,, P170,24,B12,P170_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL215W,CBP3,,Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp4p and function is partially redundant with that of Cbp4p,"mitochondrion organization, protein complex biogenesis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrion, molecular_function, organelle organization and biogenesis",,,16_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,247,4,1.6,no,,,,, P170,25,C1,P170_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL209W,CBP1,,Mitochondrial protein that interacts with the 5'-untranslated region of the COB mRNA and has a role in its stability and translation; found in a complex at the inner membrane along with Pet309p,"generation of precursor metabolites and energy, cellular respiration, RNA metabolic process",RNA binding,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","RNA binding, RNA metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion",,,10_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,316,56,17.7,no,,,,, P170,26,C2,P170_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL180C,ATP12,,Conserved protein required for assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; mutation of human ATP12 reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency,"mitochondrion organization, protein complex biogenesis",protein binding,"mitochondrion, cytoplasm","mitochondrion, organelle organization and biogenesis, protein binding",,,10_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,173,11,6.4,no,,,,, P170,27,C3,P170_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL009C,COX17,,Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs,"transport, mitochondrion organization, protein complex biogenesis",other,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, oxidoreductase activity, transport",,,12_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,182,11,6,no,,,,, P170,28,C4,P170_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL027W,ISA1,,"Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources","cofactor metabolic process, vitamin metabolic process, heterocycle metabolic process",molecular_function,"mitochondrion, cytoplasm","cytoplasm, mitochondrion, molecular_function, transport",,,12_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,206,1,0.5,no,,,,, P170,29,C5,P170_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL033W,IRC19,RRG4;GON2,Putative protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci,"sporulation resulting in formation of a cellular spore, DNA metabolic process",molecular_function,cellular_component,"DNA metabolic process, cellular_component, molecular_function, sporulation",,,12_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,181,31,17.1,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P170,30,C6,P170_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL042C,ATG10,APG10,"Conserved E2-like conjugating enzyme that mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy","transport, response to stress, protein modification process, cellular membrane organization",ligase activity,cellular_component,"cellular_component, ligase activity, membrane organization and biogenesis, protein modification process, response to stress, transport",,,12_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,173,2,1.2,no,,,,, P170,31,C7,P170_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR318C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,15_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,206,3,1.5,no,,,,, P170,32,C8,P170_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR330C,MIP1,mitochondrial DNA polymerase catalytic subunit,"Catalytic subunit of the mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome; related to human POLG, which has been associated with mitochondrial diseases","mitochondrion organization, DNA metabolic process","transferase activity, nucleotidyltransferase activity, hydrolase activity, DNA binding","mitochondrion, cytoplasm","DNA metabolic process, mitochondrion, nucleotidyltransferase activity, organelle organization and biogenesis, transferase activity",,,15_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,330,14,4.2,no,,,,, P170,33,C9,P170_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR375C,GDH1,DHE4;GDHA;GDH-A;URE1,"NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources",cellular amino acid and derivative metabolic process,oxidoreductase activity,"nucleus, cytoplasm","amino acid and derivative metabolic process, cytoplasm, nucleus, oxidoreductase activity",,,15_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,193,39,20.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P170,34,C10,P170_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL009C,MDM12,,"Mitochondrial outer membrane protein, required for transmission of mitochondria to daughter cells; component of the ERMES complex that links the ER to mitochondria; may influence import and assembly of outer membrane beta-barrel proteins","transport, mitochondrion organization, cellular membrane organization",molecular_function,"endomembrane system, mitochondrion, membrane, mitochondrial envelope, endoplasmic reticulum, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, transport",,,15_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,200,40,20,no,,,,, P170,35,C11,P170_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL033W,MSE1,mitochondrial glutamyl-tRNA synthetase,"Mitochondrial glutamyl-tRNA synthetase, predicted to be palmitoylated","mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,15_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,271,12,4.4,no,,,,, P170,36,C12,P170_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL083W,ATG34,ATG19-B,Receptor protein involved in selective autophagy during starvation; specifically involved in the transport of cargo protein alpha-mannosidase (Ams1p); Atg19p paralog,protein complex biogenesis,protein binding,cytoplasm,"biological_process, cellular_component, molecular_function",,,15_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,231,3,1.3,no,,,,, P170,37,D1,P170_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR065W,CYT1,cytochrome c1;YOR29-16;CTC1,"Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex","generation of precursor metabolites and energy, cellular respiration",other,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, other",,,15_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,174,8,4.6,no,,,,, P170,38,D2,P170_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR051W,COX6,,"Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels","generation of precursor metabolites and energy, cellular respiration","oxidoreductase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, oxidoreductase activity, transporter activity",,,08_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,253,7,2.8,no,,,,, P170,39,D3,P170_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR091C,MSR1,mitochondrial arginyl-tRNA synthetase,Mitochondrial arginyl-tRNA synthetase,"mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,08_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,296,8,2.7,no,,,,, P170,40,D4,P170_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR120W,MSH1,,"DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis","response to stress, mitochondrion organization, DNA metabolic process","DNA binding, hydrolase activity","mitochondrion, cytoplasm","DNA binding, DNA metabolic process, hydrolase activity, mitochondrion, organelle organization and biogenesis, response to stress",,,08_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,194,2,1,no,,,,, P170,41,D5,P170_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL173W,MRPL40,YmL40,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,16_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,298,12,4,no,,,,, P170,42,D6,P170_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL172C,COX10,,"Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders","cofactor metabolic process, heterocycle metabolic process",transferase activity,"mitochondrion, cytoplasm","cofactor metabolic process, heterocycle metabolic process, mitochondrion, transferase activity",,,16_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,172,5,2.9,no,,,,, P170,43,D7,P170_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL104W,MSD1,mitochondrial aspartyl-tRNA synthetase;LPG5,"Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene","mitochondrion organization, translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","ligase activity, mitochondrion, translation",,,16_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,202,7,3.5,no,,,,, P170,44,D8,P170_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR127W,RGA1,THE1;DBM1,"GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth","cell budding, signaling process, cytoskeleton organization, response to chemical stimulus, conjugation, pseudohyphal growth",enzyme regulator activity,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, conjugation, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, enzyme regulator activity, organelle organization and biogenesis, other, pseudohyphal growth, response to chemical stimulus, signal transduction, site of polarized growth",,,15_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,260,8,3.1,no,,,,, P170,45,D9,P170_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR155C,ISN1,,"Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase, catalyzes the breakdown of IMP to inosine, does not show similarity to known 5'-nucleotidases from other organisms",heterocycle metabolic process,hydrolase activity,cellular_component,"cellular_component, hydrolase activity, other",,,15_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,225,23,10.2,no,,,,, P170,46,D10,P170_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR158W,PET123,,"Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET122, which encodes a COX3 mRNA-specific translational activator","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,15_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,239,29,12.1,no,,,,, P170,47,D11,P170_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR241W,MET7,MET23,"Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA",other,ligase activity,"mitochondrion, cytoplasm","cytoplasm, ligase activity, mitochondrion, other",,,15_3,,,"rg notes: rg slow grow; consortium notes: slow grow, FAILED QC-n/g -Met, n/g Aux,n/g YP+G+E",DIC:cell structure;YFP:Rad52-YFP protein,,204,25,12.3,no,,,,, P170,48,D12,P170_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR211C,MGM1,MNA1,"Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy","mitochondrion organization, cellular membrane organization",hydrolase activity,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis",,,15_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,197,11,5.6,no,,,,, P170,49,E1,P170_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR067C,PET309,,"Specific translational activator for the COX1 mRNA, also influences stability of intron-containing COX1 primary transcripts; localizes to the mitochondrial inner membrane; contains seven pentatricopeptide repeats (PPRs)","mitochondrion organization, translation, generation of precursor metabolites and energy, cellular respiration, RNA metabolic process",translation regulator activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","RNA metabolic process, cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, translation, translation regulator activity",,,12_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,326,16,4.9,no,,,,, P170,50,E2,P170_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR069C,MEF1,,Mitochondrial elongation factor involved in translational elongation,"mitochondrion organization, translation",RNA binding,"mitochondrion, cytoplasm","mitochondrion, translation, translation regulator activity",,,12_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,262,1,0.4,no,,,,, P170,51,E3,P170_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR070C,XYL2,,"Xylitol dehydrogenase, converts xylitol to D-xylulose; expression induced by xylose, even though this pentose sugar is not well utilized by S. cerevisiae; null mutant has cell wall defect",cellular carbohydrate metabolic process,oxidoreductase activity,cellular_component,"carbohydrate metabolic process, cellular_component, oxidoreductase activity",,,12_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,261,0,0,no,,,,, P170,52,E4,P170_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR091W,GEP5,RRG5,"Protein of unknown function, required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine",mitochondrion organization,molecular_function,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,12_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,207,16,7.7,no,,,,, P170,53,E5,P170_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YHR147C,MRPL6,YmL16,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,08_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,226,2,0.9,no,,,,, P170,54,E6,P170_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR179C,FZO1,,"Mitofusin, mitochondrial integral membrane protein involved in mitochondrial fusion and mitochondrial genome maintenance; contains N-terminal GTPase domain; targeted for destruction by cytosolic components of the ubiquitin-proteasome system","mitochondrion organization, cellular membrane organization",hydrolase activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, hydrolase activity, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis",,,02_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,343,0,0,no,,,,, P170,55,E7,P170_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR251W,MRPS5,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,02_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,314,16,5.1,no,,,,, P170,56,E8,P170_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR268W,MRPL37,YmL37,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,02_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,213,2,0.9,no,,,,, P170,57,E9,P170_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCL010C,SGF29,,Probable subunit of SAGA histone acetyltransferase complex,"chromosome organization, protein modification process",molecular_function,nucleus,"molecular_function, nucleus, organelle organization and biogenesis, protein modification process",,,03_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,175,9,5.1,no,,,,, P170,58,E10,P170_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR003W,MRPL32,YmL32,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"membrane, mitochondrial envelope, ribosome, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, ribosome, structural molecule activity, translation",,,03_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,242,8,3.3,no,,,,, P170,59,E11,P170_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR175C,RSM24,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation, generation of precursor metabolites and energy, cellular respiration",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, ribosome, structural molecule activity, translation",,,04_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,328,22,6.7,no,,,,, P170,60,E12,P170_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR194C,MSS116,,DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non-polar RNA helicase that also facilities strand annealing,RNA metabolic process,"RNA binding, helicase activity, hydrolase activity","mitochondrion, cytoplasm","RNA binding, RNA metabolic process, cytoplasm, helicase activity, hydrolase activity, mitochondrion, other",,,04_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,174,6,3.4,no,,,,, P170,61,F1,P170_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR197W,CBS2,CBP7,"Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader",translation,molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, translation",,,04_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,182,5,2.7,no,,,,, P170,62,F2,P170_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR230W,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene COX20",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,196,13,6.6,no,,,,, P170,63,F3,P170_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR077W,SED1,,"Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites","fungal-type cell wall organization, mitochondrion organization",structural molecule activity,"cell wall, ribosome, mitochondrion, cytoplasm","cell wall, cell wall organization and biogenesis, mitochondrion, organelle organization and biogenesis, ribosome, structural molecule activity",,,04_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,292,0,0,no,,,,, P170,64,F4,P170_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR114C,,,Putative protein of unknown function; deletion mutant exhibits poor growth at elevated pH and calcium,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,04_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,282,32,11.3,no,,,,, P170,65,F5,P170_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR115W,,,"Putative mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L34 ribosomal protein; required for respiratory growth, as are most mitochondrial ribosomal proteins","mitochondrion organization, translation, generation of precursor metabolites and energy, cellular respiration",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, mitochondrion, ribosome, structural molecule activity",,,04_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,269,38,14.1,no,,,,, P170,66,F6,P170_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR139C,SLS1,,Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery,"mitochondrion organization, translation, generation of precursor metabolites and energy, cellular respiration",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, translation",,,12_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,176,9,5.1,no,,,,, P170,67,F7,P170_F7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR144C,ACF2,PCA1;ENG2,"Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly",cytoskeleton organization,hydrolase activity,other,"cytoskeleton organization and biogenesis, hydrolase activity, organelle organization and biogenesis, other",,,12_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,259,16,6.2,no,,,,, P170,68,F8,P170_F8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR201C,COQ9,FMP53,Protein required for ubiquinone (coenzyme Q) biosynthesis and respiratory growth; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes,"cofactor metabolic process, generation of precursor metabolites and energy, cellular respiration",molecular_function,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cofactor metabolic process, cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, molecular_function",,,12_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,223,5,2.2,no,,,,, P170,69,F9,P170_F9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR202C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YLR201C; ORF contains a putative intron",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,177,1,0.6,no,,,,, P170,70,F10,P170_F10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P170,71,F11,P170_F11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR203C,MSS51,,Specific translational activator for the mitochondrial COX1 mRNA; loosely associated with the matrix face of the mitochondrial inner membrane; influences both COX1 mRNA translation and Cox1p assembly into cytochrome c oxidase,"mitochondrion organization, translation",translation regulator activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, translation",,,12_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,214,43,20.1,no,,,,, P170,72,F12,P170_F12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR347W,MRP1,,"Mitochondrial ribosomal protein of the small subunit; MRP1 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator, and with PET123, encoding a small subunit mitochondrial ribosomal protein","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,04_7,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,212,9,4.2,no,,,,, P170,73,G1,P170_G1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR350C,ATP22,TCM10,"Specific translational activator for the mitochondrial ATP6 mRNA, encoding a subunit of F1F0 ATP synthase; localized to the mitochondrial inner membrane","mitochondrion organization, translation",translation regulator activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, membrane, mitochondrial envelope, mitochondrion, molecular_function, other",,,04_7,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,221,9,4.1,no,,,,, P170,74,G2,P170_G2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR375C,BCS1,,Mitochondrial protein of the AAA ATPase family; has ATP-dependent chaperone activity; required for assembly of Rip1p and Qcr10p into cytochrome bc(1) complex; mutations in human homolog BCS1L are linked to neonatal mitochondrial diseases,"mitochondrion organization, generation of precursor metabolites and energy, protein complex biogenesis, cellular respiration",hydrolase activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","cellular respiration, cytoplasm, generation of precursor metabolites and energy, hydrolase activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other",,,04_7,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,201,7,3.5,no,,,,, P170,75,G3,P170_G3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR062C,COX18,OXA2,"Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC","mitochondrion organization, cellular membrane organization",transporter activity,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transporter activity",,,07_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,357,0,0,no,,,,, P170,76,G4,P170_G4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR076C,MRPL25,AFO1;YmL25;YMR26,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,07_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,248,24,9.7,no,,,,, P170,77,G5,P170_G5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR102C,,,Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; transposon insertion mutant is salt sensitive and null mutant has growth defects; non-tagged protein is detected in purified mitochondria,"cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,212,1,0.5,no,,,,, P170,78,G6,P170_G6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR150C,CCM1,DMR1;RRG2,Mitochondrial 15s rRNA-binding protein; required for intron removal of COB and COX1 pre-mRNAs; contains pentatricopeptide repeat (PPR) motifs; mutant is respiratory deficient and has defective plasma membrane electron transport,"mitochondrion organization, RNA metabolic process",RNA binding,"mitochondrion, cytoplasm","biological_process, mitochondrion, molecular_function",,,07_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,254,4,1.6,no,,,,, P170,79,G7,P170_G7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR167W,CLC1,SCD4,"Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; thought to regulate clathrin function; two Clathrin heavy chains (CHC1) form the clathrin triskelion structural component","transport, vesicle-mediated transport, cellular membrane organization",structural molecule activity,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, membrane organization and biogenesis, structural molecule activity, transport, vesicle-mediated transport",,,07_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,292,2,0.7,no,,,,, P170,80,G8,P170_G8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR171C,MSM1,mitochondrial methionyl-tRNA synthetase,"Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p","translation, cellular amino acid and derivative metabolic process, RNA metabolic process",ligase activity,"mitochondrion, cytoplasm","RNA metabolic process, amino acid and derivative metabolic process, ligase activity, mitochondrion, translation",,,07_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,284,6,2.1,no,,,,, P170,81,G9,P170_G9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR174C,CBP4,,Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp3p and function is partially redundant with that of Cbp3p,"mitochondrion organization, protein complex biogenesis",molecular_function,"membrane, mitochondrial envelope, mitochondrion, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrion, molecular_function, organelle organization and biogenesis",,,07_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,172,1,0.6,no,,,,, P170,82,G10,P170_G10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR180C,RNR4,PSO3;CRT3,"Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits",cofactor metabolic process,oxidoreductase activity,"nucleus, cytoplasm","cofactor metabolic process, cytoplasm, nucleus, other, oxidoreductase activity",,,07_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,311,0,0,no,,,,, P170,83,G11,P170_G11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR215W,RSM27,,Mitochondrial ribosomal protein of the small subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,07_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,191,2,1,no,,,,, P170,84,G12,P170_G12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL003C,MRP17,,"Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator","mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,11_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,183,39,21.3,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P170,85,H1,P170_H1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL016C,ATP7,,"Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis","transport, heterocycle metabolic process, protein complex biogenesis","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, other, transport, transporter activity",,,11_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,219,5,2.3,no,,,,, P170,86,H2,P170_H2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL114C,APN1,,"Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine","response to stress, DNA metabolic process","lyase activity, hydrolase activity","nucleus, mitochondrion, cytoplasm","DNA metabolic process, hydrolase activity, lyase activity, mitochondrion, nucleus, response to stress",,,11_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,317,2,0.6,no,,,,, P170,87,H3,P170_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P170,88,H4,P170_H4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL134C,OCT1,mitochondrial intermediate peptidase,"Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis","transport, mitochondrion organization, cellular homeostasis","peptidase activity, hydrolase activity","mitochondrion, cytoplasm","cellular homeostasis, hydrolase activity, mitochondrion, organelle organization and biogenesis, peptidase activity, protein modification process, transport",,,11_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,226,4,1.8,no,,,,, P170,89,H5,P170_H5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL138C,MRPL31,YmL31,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,11_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,181,2,1.1,no,,,,, P170,90,H6,P170_H6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL169C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene MRPL38",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,11_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,215,5,2.3,no,,,,, P170,91,H7,P170_H7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL170W,MRPL38,YmL38;YmL34;MRPL34,Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,11_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,177,8,4.5,no,,,,, P170,92,H8,P170_H8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YMR231W,PEP5,VPT11;VPS11;VPL9;VAM1;END1,Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p,"vacuole organization, transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular membrane organization",lipid binding,"vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, transport, vacuole, vesicle-mediated transport",,,13_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,199,26,13.1,no,,,,, P170,93,H9,P170_H9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLL006W,MMM1,YME6,"ER integral membrane protein, component of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth","transport, mitochondrion organization, cellular membrane organization",molecular_function,"endomembrane system, mitochondrion, membrane, mitochondrial envelope, endoplasmic reticulum, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, mitochondrial envelope, mitochondrion, molecular_function, organelle organization and biogenesis, transport",,,12_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,181,2,1.1,no,,,,, P170,94,H10,P170_H10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR148W,PEP3,VPT18;VPS18;VAM8,"Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis","vacuole organization, transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular membrane organization","lipid binding, protein binding","vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, protein binding, response to chemical stimulus, transport, vacuole, vesicle-mediated transport",,,12_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,219,2,0.9,no,,,,, P170,95,H11,P170_H11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL002W,DID4,VPS14;CHM2;VPS2;VPT14;VPL2;REN1;GRD7,"Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis","transport, vesicle-mediated transport, vesicle organization, cellular protein catabolic process, cellular membrane organization",molecular_function,"membrane, cytoplasm","cytoplasm, membrane, other, protein binding, protein catabolic process, transport, vesicle-mediated transport",,,11_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,181,2,1.1,no,,,,, P170,96,H12,P170_H12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKL087C,CYT2,CC1HL;cytochrome c1 heme lyase,"Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1","protein modification process, protein complex biogenesis",lyase activity,"mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, lyase activity, mitochondrial envelope, mitochondrion, protein modification process",,,11_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,192,12,6.3,no,,,,, P171,1,A1,P171_A1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR377W,ATP17,,"Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis","transport, heterocycle metabolic process","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,04_7,,,rg notes: rg slow grow; consortium notes: slow grow-no glyc,DIC:cell structure;YFP:Rad52-YFP protein,,304,16,5.3,no,,,,, P171,2,A2,P171_A2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR240W,VPS34,VPS7;STT8;VPT29;VPL7;PEP15;END12,Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p,"cellular lipid metabolic process, protein modification process","transferase activity, protein kinase activity","membrane, vacuole, cytoplasm","cytoplasm, lipid metabolic process, membrane, protein kinase activity, protein modification process, transferase activity, vacuole",,,12_4,,,rg notes: rg slow grow; consortium notes: slow grow-no glyc,DIC:cell structure;YFP:Rad52-YFP protein,,314,36,11.5,no,,,,, P171,3,A3,P171_A3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YCR094W,CDC50,,Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p,"transport, vesicle-mediated transport, cellular membrane organization","hydrolase activity, transporter activity","membrane fraction, Golgi apparatus, cytoplasm","Golgi apparatus, cell cycle, cytoplasm, hydrolase activity, membrane fraction, membrane organization and biogenesis, other, transport, transporter activity, vesicle-mediated transport",,,00_2,,,rg notes: rg slow grow; consortium notes: slow grow-no glyc,DIC:cell structure;YFP:Rad52-YFP protein,,190,5,2.6,no,,,,, P171,4,A4,P171_A4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL220W,ADE12,BRA9,"Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence",heterocycle metabolic process,"DNA binding, ligase activity",cytoplasm,"DNA binding, cytoplasm, ligase activity, other",,,00_18,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,229,7,3.1,no,,,,, P171,5,A5,P171_A5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL243W,SLA2,MOP2;END4,Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo,"transport, fungal-type cell wall organization, cell budding, cytoskeleton organization, cytokinesis, vesicle-mediated transport, cell cycle, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cell wall organization and biogenesis, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, other, protein binding, transport, vesicle-mediated transport",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,317,0,0,no,,,,, P171,6,A6,P171_A6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL242W,ATG2,APG2;AUT8;SPO72,"Peripheral membrane protein required for vesicle formation during autophagy, pexophagy, and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria","vacuole organization, transport, peroxisome organization, response to stress, cellular membrane organization",molecular_function,"membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, molecular_function, organelle organization and biogenesis, response to stress, transport",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,177,3,1.7,no,,,,, P171,7,A7,P171_A7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL239W,LAP3,YCP1;GAL6;BLH1,Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH,"cellular amino acid and derivative metabolic process, response to chemical stimulus","peptidase activity, transcription regulator activity, hydrolase activity","mitochondrion, cytoplasm","amino acid and derivative metabolic process, cytoplasm, hydrolase activity, mitochondrion, other, peptidase activity, response to chemical stimulus, transcription regulator activity",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,171,1,0.6,no,,,,, P171,8,A8,P171_A8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL237W,YTP1,,"Probable type-III integral membrane protein of unknown function, has regions of similarity to mitochondrial electron transport proteins",biological_process,molecular_function,membrane,"biological_process, membrane, molecular_function",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,184,1,0.5,no,,,,, P171,9,A9,P171_A9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL236W,SIN4,MED16;RYE1;TSF3;SSN4;SSF5;SDI3;GAL22;BEL2,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,243,3,1.2,no,,,,, P171,10,A10,P171_A10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL231C,PDR16,SFH3,"Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p","transport, response to chemical stimulus",transporter activity,"membrane fraction, cytoplasm","cytoplasm, lipid metabolic process, membrane fraction, response to chemical stimulus, transport, transporter activity",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,302,0,0,no,,,,, P171,11,A11,P171_A11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL230C,ELA1,,"Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex","transcription, protein modification process, cellular protein catabolic process, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, other, protein catabolic process, protein modification process, transcription, transcription regulator activity",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,187,3,1.6,no,,,,, P171,12,A12,P171_A12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL227C,JJJ1,,"Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis","transport, vesicle-mediated transport, ribosome biogenesis, RNA metabolic process, cellular membrane organization",enzyme regulator activity,"nucleus, ribosome, mitochondrion, nucleolus, cytoplasm","cytoplasm, enzyme regulator activity, membrane organization and biogenesis, mitochondrion, organelle organization and biogenesis, other, ribosome, ribosome biogenesis, transport, vesicle-mediated transport",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,196,3,1.5,no,,,,, P171,13,B1,P171_B1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL225C,CNM67,,Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclear migration,"cytoskeleton organization, cell cycle",structural molecule activity,"cytoskeleton, microtubule organizing center, cytoplasm","cell cycle, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, microtubule organizing center, organelle organization and biogenesis, structural molecule activity",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,288,2,0.7,no,,,,, P171,14,B2,P171_B2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL219C,ALG9,,"Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation","cellular carbohydrate metabolic process, protein modification process",transferase activity,"endoplasmic reticulum, cytoplasm","endoplasmic reticulum, protein modification process, transferase activity",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,181,3,1.7,no,,,,, P171,15,B3,P171_B3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL213C,RRG9,,"Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies",mitochondrion organization,molecular_function,"mitochondrion, cytoplasm","mitochondrion, molecular_function, organelle organization and biogenesis",,,14_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,183,3,1.6,no,,,,, P171,16,B4,P171_B4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YKR055W,RHO4,,"Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity",cytoskeleton organization,hydrolase activity,"cellular bud, membrane, site of polarized growth, membrane fraction, plasma membrane","anatomical structure morphogenesis, cytoskeleton organization and biogenesis, hydrolase activity, organelle organization and biogenesis, other, signal transducer activity, signal transduction",,,11_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,234,17,7.3,no,,,,, P171,17,B5,P171_B5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YML094C-A,,YML095C-A,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene GIM5/YML094W; deletion confers sensitivity to GSAO",biological_process,molecular_function,cellular_component,"cellular_component, molecular_function, response to chemical stimulus",,,00_9,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,174,26,14.9,no,,,,, P171,18,B6,P171_B6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL127C,SPT10,SUD1;CRE1,"Putative histone acetylase, sequence-specific activator of histone genes, binds specifically and highly cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box","response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process","transferase activity, DNA binding",nucleus,"DNA binding, DNA metabolic process, RNA metabolic process, nucleus, organelle organization and biogenesis, response to stress, transcription, transferase activity",,,10_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,175,12,6.9,no,,,,, P171,19,B7,P171_B7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL124C,LSM1,SPB8,"Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs",RNA metabolic process,RNA binding,cytoplasm,"RNA binding, RNA metabolic process, cytoplasm, other",,,10_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,175,12,6.9,no,,,,, P171,20,B8,P171_B8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL102W,MEF2,,Mitochondrial elongation factor involved in translational elongation,translation,RNA binding,"mitochondrion, cytoplasm","mitochondrion, translation, translation regulator activity",,,10_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,260,16,6.2,no,,,,, P171,21,B9,P171_B9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL096W,MRPL49,YmL49,Mitochondrial ribosomal protein of the large subunit,"mitochondrion organization, translation",structural molecule activity,"ribosome, mitochondrion, cytoplasm","cytoplasm, mitochondrion, ribosome, structural molecule activity, translation",,,10_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,197,14,7.1,no,,,,, P171,22,B10,P171_B10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL079C,PRY1,,Protein of unknown function,biological_process,molecular_function,"nucleus, extracellular region, endomembrane system, vacuole, endoplasmic reticulum, cytoplasm","biological_process, cytoplasm, endomembrane system, endoplasmic reticulum, extracellular region, molecular_function, nucleus, vacuole",,,10_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,189,7,3.7,no,,,,, P171,23,B11,P171_B11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOL143C,RIB4,,"Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, also known as DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin",vitamin metabolic process,isomerase activity,"nucleus, cytoplasm","cytoplasm, isomerase activity, nucleus, vitamin metabolic process",,,00_10,,,rg notes: rg slow grow; consortium notes: slow grow-riboflavin auxotroph,DIC:cell structure;YFP:Rad52-YFP protein,,279,0,0,no,,,,, P171,24,B12,P171_B12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR435W,TSR2,,Protein with a potential role in pre-rRNA processing,"ribosome biogenesis, RNA metabolic process",molecular_function,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, molecular_function, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,00_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,230,5,2.2,no,,,,, P171,25,C1,P171_C1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YAL016W,TPD3,FUN32,"Regulatory subunit A of the heterotrimeric protein phosphatase 2A (PP2A), which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and transcription by RNA polymerase III","cell budding, signaling process, cytoskeleton organization, translation, protein modification process, cell cycle","hydrolase activity, phosphoprotein phosphatase activity","nucleus, cytoskeleton, microtubule organizing center, cellular bud, site of polarized growth, cytoplasm","cell budding, cell cycle, cellular bud, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, hydrolase activity, microtubule organizing center, nucleus, organelle organization and biogenesis, other, phosphoprotein phosphatase activity, protein modification process, site of polarized growth, translation",,,00_12,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,201,14,7,no,,,,, P171,26,C2,P171_C2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL218W,,SRF1,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 93% of ORF overlaps the verified gene MDM34; deletion in cyr1 mutant results in loss of stress resistance",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,00_12,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,243,3,1.2,no,,,,, P171,27,C3,P171_C3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR039W,ATP3,,"Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis","transport, heterocycle metabolic process","hydrolase activity, transporter activity","mitochondrion, membrane, mitochondrial envelope, cytoplasm","cytoplasm, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, transport, transporter activity",,,2_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,216,9,4.2,no,,,,, P171,28,C4,P171_C4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL139C,THO2,RLR1;LDB5;ZRG13,"Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids","transport, response to stress, transcription, DNA metabolic process, RNA metabolic process",DNA binding,nucleus,"DNA binding, DNA metabolic process, RNA metabolic process, nucleus, other, response to stress, transcription, transport",,,14_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,181,3,1.7,no,,,,, P171,29,C5,P171_C5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YIL154C,IMP2,IMP2,"Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants, contains a C-terminal leucine-rich repeat","response to stress, cellular carbohydrate metabolic process, DNA metabolic process","transcription regulator activity, protein binding",cytoplasm,"DNA metabolic process, carbohydrate metabolic process, cytoplasm, protein binding, response to stress, transcription regulator activity",,,9_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,250,4,1.6,no,,,,, P171,30,C6,P171_C6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL184W,GON7,PCC2;LDB6,"Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p","chromosome organization, transcription, DNA metabolic process, RNA metabolic process",DNA binding,"nucleus, chromosome","DNA binding, RNA metabolic process, cell wall organization and biogenesis, chromosome, nucleus, organelle organization and biogenesis, other, response to stress, transcription",,,00_14,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,177,1,0.6,no,,,,, P171,31,C7,P171_C7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL138W,SRV2,CAP,"CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis","signaling process, cytoskeleton organization, pseudohyphal growth",protein binding,"cell cortex, cytoskeleton, site of polarized growth, cytoplasm","cell cortex, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, protein binding, pseudohyphal growth, signal transduction",,,00_17,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,230,1,0.4,no,,,,, P171,32,C8,P171_C8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPL268W,PLC1,,"Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes","cellular carbohydrate metabolic process, signaling process, cellular lipid metabolic process",hydrolase activity,"nucleus, chromosome","chromosome, hydrolase activity, lipid metabolic process, nucleus, other, signal transduction",,,00_15,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,198,9,4.5,no,,,,, P171,33,C9,P171_C9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR067W,ISA2,,"Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations","cofactor metabolic process, vitamin metabolic process, heterocycle metabolic process",molecular_function,"mitochondrial envelope, mitochondrion, cytoplasm","cofactor metabolic process, cytoplasm, heterocycle metabolic process, mitochondrial envelope, mitochondrion, molecular_function, response to chemical stimulus, transport, vitamin metabolic process",,,00_15,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,226,7,3.1,no,,,,, P171,34,C10,P171_C10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBR097W,VPS15,VPS40;VPL19;VAC4;GRD8,Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p,"vacuole organization, transport, signaling process, protein modification process, response to stress, vesicle-mediated transport","transferase activity, protein kinase activity","endomembrane system, mitochondrion, membrane, Golgi apparatus, cytoplasm","Golgi apparatus, cytoplasm, endomembrane system, membrane, mitochondrion, other, protein kinase activity, protein modification process, response to stress, signal transduction, transferase activity, transport, vesicle-mediated transport",,,2_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,194,10,5.2,no,,,,, P171,35,C11,P171_C11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL038C,OCH1,LDB12;NGD29,"Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, protein modification process, transferase activity",,,7_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,258,21,8.1,no,,,,, P171,36,C12,P171_C12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL029W,CGR1,,Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress,"ribosome biogenesis, RNA metabolic process",molecular_function,"nucleus, nucleolus","RNA metabolic process, cytoplasm, molecular_function, nucleolus, nucleus, organelle organization and biogenesis, ribosome biogenesis",,,7_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,188,11,5.9,no,,,,, P171,37,D1,P171_D1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL206C,CHC1,SWA5,"Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; two heavy chains form the clathrin triskelion structural component; the light chain (CLC1) is thought to regulate function","transport, vesicle-mediated transport, cellular membrane organization",structural molecule activity,"membrane, cytoplasmic membrane-bounded vesicle, endomembrane system, cytoplasm","cytoplasm, cytoplasmic membrane-bounded vesicle, endomembrane system, membrane, membrane organization and biogenesis, structural molecule activity, transport, vesicle-mediated transport",,,07_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,338,18,5.3,no,,,,, P171,38,D2,P171_D2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL240W,DOC1,APC10,"Processivity factor required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis","cytoskeleton organization, chromosome segregation, chromosome organization, cell cycle, cellular protein catabolic process",enzyme regulator activity,"nucleus, mitochondrion, cytoplasm","cell cycle, cytoskeleton organization and biogenesis, enzyme regulator activity, mitochondrion, nucleus, organelle organization and biogenesis, protein catabolic process",,,07_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,308,26,8.4,no,,,,, P171,39,D3,P171_D3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL223C,COG1,SEC36;LDB11;COD3,"Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments","transport, vesicle-mediated transport",molecular_function,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, molecular_function, transport, vesicle-mediated transport",,,07_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,213,11,5.2,no,,,,, P171,40,D4,P171_D4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGR262C,BUD32,LDB14,"Protein kinase proposed to be involved in bud-site selection, telomere uncapping and elongation, and transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Gon7p","cytokinesis, transcription, protein modification process, chromosome organization, cell cycle, DNA metabolic process, RNA metabolic process","transferase activity, protein kinase activity","nucleus, cytoplasm","RNA metabolic process, anatomical structure morphogenesis, cytokinesis, cytoplasm, nucleus, organelle organization and biogenesis, other, protein kinase activity, protein modification process, transcription, transferase activity",,,00_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,178,1,0.6,no,,,,, P171,41,D5,P171_D5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YGL242C,,,Putative protein of unknown function; deletion mutant is viable,biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,07_3,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,268,17,6.3,no,,,,, P171,42,D6,P171_D6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL093C,ROX3,MED19;SSN7;NUT3,Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme,"transcription, RNA metabolic process",transcription regulator activity,nucleus,"RNA metabolic process, nucleus, transcription, transcription regulator activity",,,02_1,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,188,18,9.6,no,,,,, P171,43,D7,P171_D7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YPR072W,NOT5,,"Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation","transcription, protein modification process, RNA metabolic process",ligase activity,"nucleus, cytoplasm","RNA metabolic process, cytoplasm, ligase activity, nucleus, protein modification process, transcription",,,16_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,179,5,2.8,no,,,,, P171,44,D8,P171_D8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL084C,ALY2,ART3,"Protein proposed to regulate the endocytosis of plasma membrane proteins; interacts with the cyclin Pcl7p and ubiquitin ligase Rsp5p; phosphorylated by the cyclin-CDK complex, Pcl7p-Pho85p; mRNA is cell cycle regulated, peaking in M phase","transport, vesicle-mediated transport, cellular membrane organization",protein binding,cytoplasm,"biological_process, cytoplasm, protein binding",,,10_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,270,36,13.3,no,,,,, P171,45,D9,P171_D9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YJL075C,APQ13,,"Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene NET1; null mutant is sensitive to sorbate",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,10_2,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,296,14,4.7,no,,,,, P171,46,D10,P171_D10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR532C,KRE28,,"Subunit of a kinetochore-microtubule binding complex with Spc105p that bridges centromeric heterochromatin and kinetochore MAPs and motors, and is also required for sister chromatid bi-orientation and kinetochore binding of SAC components",biological_process,molecular_function,"nucleus, cytoskeleton, microtubule organizing center, chromosome, cytoplasm","biological_process, chromosome, cytoplasm, cytoskeleton, microtubule organizing center, molecular_function",,,4_8,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,338,26,7.7,no,,,,, P171,47,D11,P171_D11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER014C-A,BUD25,,Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern,"cytokinesis, cell cycle",molecular_function,cellular_component,"anatomical structure morphogenesis, cellular_component, cytokinesis, molecular_function",,,05_3,,,"rg notes: rg slow grow; consortium notes: slow grow, Failed qc-- growth-lys no mating a, a",DIC:cell structure;YFP:Rad52-YFP protein,,254,9,3.5,no,,,,, P171,48,D12,P171_D12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR233C,EST1,,TLC1 RNA-associated factor involved in telomere length regulation as recruitment subunit of telomerase; has G-quadruplex promoting activity that is required for telomere elongation; possible role in activating telomere-bound Est2p-TLC1-RNA,"chromosome organization, DNA metabolic process","RNA binding, DNA binding","nucleus, nucleolus","DNA binding, DNA metabolic process, RNA binding, nucleolus, nucleotidyltransferase activity, nucleus, organelle organization and biogenesis, transferase activity",,,12_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,268,3,1.1,no,,,,, P171,49,E1,P171_E1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR234W,TOP3,EDR1,"DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination","chromosome segregation, meiosis, chromosome organization, cell cycle, DNA metabolic process","isomerase activity, DNA binding","nucleus, chromosome","DNA binding, DNA metabolic process, cell cycle, chromosome, isomerase activity, meiosis, nucleus, organelle organization and biogenesis",,,12_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,259,5,1.9,no,,,,, P171,50,E2,P171_E2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR235C,,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TOP3",response to stress,molecular_function,cellular_component,"cellular_component, molecular_function, response to stress",,,12_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,264,6,2.3,no,,,,, P171,51,E3,P171_E3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR239C,LIP2,,"Lipoyl ligase, involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups",protein modification process,ligase activity,"mitochondrion, cytoplasm","ligase activity, mitochondrion, protein modification process",,,12_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,254,2,0.8,no,,,,, P171,52,E4,P171_E4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR242C,ARV1,,Protein functioning in transport of glycosylphosphatidylinositol intermediates into ER lumen; required for normal intracellular sterol distribution; human ARV1 required for normal cholesterol and bile acid homeostasis; similar to Nup120p,"transport, cellular lipid metabolic process",molecular_function,"membrane, endoplasmic reticulum, cytoplasm, Golgi apparatus","Golgi apparatus, endoplasmic reticulum, lipid metabolic process, membrane, molecular_function, transport",,,12_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,199,10,5,no,,,,, P171,53,E5,P171_E5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR244C,MAP1,,"Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p",protein modification process,"peptidase activity, hydrolase activity","ribosome, cytoplasm","cytoplasm, hydrolase activity, other, peptidase activity, ribosome",,,12_4,,,rg notes: rg slow grow; consortium notes: slow grow-no glyc,DIC:cell structure;YFP:Rad52-YFP protein,images not available,187,2,1.1,no,,,,, P171,54,E6,P171_E6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR399C,BDF1,,Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p,"response to stress, meiosis, sporulation resulting in formation of a cellular spore, chromosome organization, cell cycle, DNA metabolic process","transcription regulator activity, protein binding","nucleus, chromosome","DNA metabolic process, chromosome, meiosis, nucleus, organelle organization and biogenesis, response to stress, sporulation, transcription regulator activity",,,12_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,198,46,23.2,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P171,55,E7,P171_E7,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR338W,OPI9,,"Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF VRP1/YLR337C",biological_process,molecular_function,cellular_component,"biological_process, cellular_component, molecular_function",,,12_5,,,rg notes: rg slow grow; consortium notes: slow grow-no glyc,DIC:cell structure;YFP:Rad52-YFP protein,images not available,212,10,4.7,no,,,,, P171,56,E8,P171_E8,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR337C,VRP1,verprolin;YLR337W;MDP2;END5,Proline-rich actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP),"transport, cell budding, cytoskeleton organization, cytokinesis, vesicle-mediated transport, cell cycle, cellular membrane organization",protein binding,"cell cortex, cytoskeleton, cellular bud, site of polarized growth, cytoplasm","anatomical structure morphogenesis, cell budding, cell cortex, cellular bud, cytokinesis, cytoplasm, cytoskeleton, cytoskeleton organization and biogenesis, membrane organization and biogenesis, organelle organization and biogenesis, other, protein binding, site of polarized growth, transport, vesicle-mediated transport",,,12_5,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,images not available,236,6,2.5,no,,,,, P171,57,E9,P171_E9,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR396C,VPS33,VPT33;VPL25;VAM5;SLP1;PEP14;MET27;CLS14,"ATP-binding protein that is a subunit of the HOPS complex and of the CORVET tethering complex; essential for protein sorting, vesicle docking and fusion at the vacuole","vacuole organization, transport, vesicle organization, protein complex biogenesis, vesicle-mediated transport, cellular membrane organization",lipid binding,"vacuole, membrane, cytoplasm","cytoplasm, membrane, membrane organization and biogenesis, organelle organization and biogenesis, other, transport, vacuole, vesicle-mediated transport",,,12_5,,,rg notes: rg slow grow; consortium notes: slow grow-no glyc,DIC:cell structure;YFP:Rad52-YFP protein,images not available,239,18,7.5,no,,,,, P171,58,E10,P171_E10,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL036C,ANP1,MNN8;GEM3,"Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol","cellular carbohydrate metabolic process, protein modification process",transferase activity,"cytoplasm, Golgi apparatus","Golgi apparatus, cytoplasm, protein modification process, transferase activity",,,05_2,,,rg notes: rg slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,175,15,8.6,no,,,,, P171,59,E11,P171_E11,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YEL044W,IES6,,Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions; human ortholog INO80C is a member of the human INO80 complex; implicated in DNA repair based on genetic interactions with RAD52 epistasis genes,biological_process,molecular_function,nucleus,"molecular_function, nucleus, other",,,05_2,,,rg notes: rg slow grow; consortium notes: slow grow-no glyc-petite,DIC:cell structure;YFP:Rad52-YFP protein,,246,28,11.4,no,,,,, P171,60,E12,P171_E12,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YER068W,MOT2,SIG1;NOT4,"Subunit of the CCR4-NOT complex, which has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p","transcription, protein modification process, conjugation, RNA metabolic process","transcription regulator activity, ligase activity, DNA binding","nucleus, cytoplasm","RNA metabolic process, conjugation, cytoplasm, ligase activity, nucleus, protein modification process, transcription, transcription regulator activity",,,05_3,,,rg notes: rg slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,210,16,7.6,no,,,,, P171,61,F1,P171_F1,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YDR138W,HPR1,TRF1,"Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p","transport, response to stress, transcription, DNA metabolic process, RNA metabolic process",other,nucleus,"DNA metabolic process, RNA metabolic process, nucleus, other, response to stress, transcription, transport",,,04_4,,,rg notes: rg slow grow; consortium notes: sick per db,DIC:cell structure;YFP:Rad52-YFP protein,,267,56,21,yes,yes,gene,increased level of spontaneous Rad52-YFP foci,cell response to DNA damage phenotype,CMPO_0000415 P171,62,F2,P171_F2,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YOR290C,SNF2,TYE3;SWI2;HAF1;GAM1,Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p,"response to stress, chromosome organization, transcription, DNA metabolic process, RNA metabolic process","transcription regulator activity, protein binding, hydrolase activity",nucleus,"DNA metabolic process, RNA metabolic process, hydrolase activity, nucleus, organelle organization and biogenesis, response to stress, transcription, transcription regulator activity",,,15_4,,,rg notes: rg slow grow; consortium notes: slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,190,12,6.3,no,,,,, P171,63,F3,P171_F3,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YLR369W,SSQ1,SSH1;SSC2,"Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia","cofactor metabolic process, cellular homeostasis",protein binding,"mitochondrion, cytoplasm","DNA metabolic process, cellular homeostasis, cofactor metabolic process, cytoplasm, mitochondrion, protein binding",,,12_5,,,rg notes: rg slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,227,10,4.4,no,,,,, P171,64,F4,P171_F4,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YFL016C,MDJ1,,Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones,"response to stress, protein folding, mitochondrion organization, cellular protein catabolic process","protein binding, enzyme regulator activity","membrane, mitochondrial envelope, mitochondrion, cytoplasm","cytoplasm, enzyme regulator activity, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, other, protein binding, protein catabolic process, protein folding, response to stress",,,00_17,,,rg notes: rg slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,228,9,3.9,no,,,,, P171,65,F5,P171_F5,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YNL055C,POR1,VDAC;YVDAC1;OMP2,"Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; phosphorylated","transport, mitochondrion organization, cellular homeostasis",transporter activity,"mitochondrion, membrane, mitochondrial envelope, cytoplasm","Golgi apparatus, cellular respiration, cytoplasm, endomembrane system, generation of precursor metabolites and energy, membrane, mitochondrial envelope, mitochondrion, organelle organization and biogenesis, transport, transporter activity",,,00_18,,,rg notes: rg slow grow,DIC:cell structure;YFP:Rad52-YFP protein,,268,2,0.7,no,,,,, P171,66,F6,P171_F6,Saccharomyces cerevisiae,NCBITaxon,NCBITaxon_4932,BY4742,YBL033C,RIB1,,GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway,vitamin metabolic process,hydrolase activity,"nucleus, cytoplasm","cytoplasm, hydrolase activity, nucleus, response to chemical stimulus, vitamin metabolic process",,,02_1,,,rg notes: rg slow grow--grown in tube w/ motion & added to plate,DIC:cell structure;YFP:Rad52-YFP protein,,262,0,0,no,,,,, P171,67,F7,P171_F7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,68,F8,P171_F8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,69,F9,P171_F9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,70,F10,P171_F10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,71,F11,P171_F11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,72,F12,P171_F12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,73,G1,P171_G1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,74,G2,P171_G2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,75,G3,P171_G3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,76,G4,P171_G4,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,77,G5,P171_G5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,78,G6,P171_G6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,79,G7,P171_G7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,80,G8,P171_G8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,81,G9,P171_G9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,82,G10,P171_G10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,83,G11,P171_G11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,84,G12,P171_G12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,85,H1,P171_H1,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,86,H2,P171_H2,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,87,H3,P171_H3,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,88,H4,P171_H4,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,89,H5,P171_H5,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,90,H6,P171_H6,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,91,H7,P171_H7,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,92,H8,P171_H8,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,93,H9,P171_H9,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,94,H10,P171_H10,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,95,H11,P171_H11,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,, P171,96,H12,P171_H12,,,,,,,,,,,,,,,,,,,,annotation not available; images not available,,,,,,,,,