Devices, Experimental scaffolds and Biomaterials Ontology (DEB)
type: Ontology
creator: Osnat Hakimi
description: An ontology developed to facilitate information curation in the area of medical devices, experimental scaffolds and biomaterials. The ontology was designed to complement existing medical vocabularies, with emphasis on material procesing, structures and features associated with biomaterials and experimental scaffolds.

funcionalized
type: DatatypeProperty
sub property of: treated
domain: Biomaterial
domain: Manufactured Object
domain: Manufactured Object Component
range: boolean
alternative label: functionalised

nanoscale
type: DatatypeProperty
domain: Manufactured Object
domain: Manufactured Object Component
range: boolean
alternative label: nanosized

not treated
type: DatatypeProperty
domain: Biomaterial
domain: Manufactured Object
domain: Manufactured Object Component
range: boolean
alternative label: untreated

Absorption
type: Class
subclass of: Degradation Features
subclass of: Restriction
  on property: absorbable
  has value: true

Acellularity
type: Class
subclass of: OtherFeatures
subclass of: Restriction
  on property: acellular
  has value: true

Adipogenesis
type: Class
subclass of: AssociatedBiologicalProcess
definition: The production of fat, either fatty degeneration or fatty infiltration; also applied to the normal deposition of fat or to the conversion of carbohydrate or protein to fat. (Source: NCIT)
has alternative id: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20906

Adsorption
type: Class
subclass of: Coating
subclass of: Restriction
  on property: adsorbed
  has value: true
definition: Adsorption can be defined as the accumulation of a substance or material at an interface between the solid surface and the bathing solution. From: Encyclopedia of Soils in the Environment, 2005

AdverseEffects
type: Class
subclass of: Effect on Biological System
description: An unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical device or biomaterial
alternative label: Adverse event

Alignment
type: Class
subclass of: ArchitecturalOrganization
alternative label: Aligned

Alloy
type: Class
subclass of: Biomaterial Type
description: mixture of two or more metals or of one or more metals with certain metalloids that are mutually soluble in the molten condition; distinguished as binary, ternary, quaternary, etc., depending on the number of metals in the mixture. [CRISP]
has alternative id: http://purl.bioontology.org/ontology/CSP/1852-6667
has alternative id: http://purl.obolibrary.org/obo/CHEBI_142648

Anisotropy
type: Class
subclass of: MechanicalProperty
description: The property of being anisotropic, having a different value when measured in different directions.
has alternative id: ncit:C17442

Annealing
type: Class
subclass of: Material Processing
description: A heat treatment that alters the microstructure of a material causing changes in its properties such as strength and hardness
has alternative id: http://purl.obolibrary.org/obo/CHMO_0001465

AntibacterialEffect
type: Class
subclass of: AntimicrobialEffect
subclass of: Restriction
  on property: antibacterial
  has value: true

AntimicrobialEffect
type: Class
subclass of: Effect on Biological System
subclass of: Restriction
  on property: antimicrobial
  has value: true

ArchitecturalOrganization
type: Class
subclass of: Manufactured Object Features
definition: Characteristics related to the three dimensional organization, orientation and assembly of a manufactured object or its components.

ArtificialConduits
type: Class
subclass of: Conduit
has alternative id: http://purl.bioontology.org/ontology/SNOMEDCT/257281002
alternative label: A nerve guidance conduit
alternative label: Conduit

AssociatedBiologicalProcess
type: Class
definition: A cellular or biological process that the manufactured object is designed to cause or support, or is measured to affect
has alternative id: ncit:C17828
alternative label: Biological Process

BMP
type: Class
subclass of: Biologically Active Substance
has alternative id: PR:000000034
has obo namespace: protein

Bioactivity
type: Class
subclass of: Effect on Biological System
subclass of: Restriction
  on property: bioactive
  has value: true

Bioceramic
type: Class
subclass of: Ceramic
description: Ceramics with biological functionality.

Biocompatibility
type: Class
subclass of: Effect on Biological System
subclass of: Restriction
  on property: biocompatible
  has value: true

Biodegradability
type: Class
subclass of: Degradation Features
subclass of: Restriction
  on property: biodegradable
  has value: true
alternative label: Bioabsorbable
alternative label: Biodegradation
alternative label: Bioresorption

Biofabrication
type: Class
subclass of: Material Processing
description: The production of complex biologic products from raw materials such as living cells, matrices, biomaterials, and molecules.
has alternative id: http://purl.jp/bio/4/id/201606009447904933

Biofunctionalization
type: Class
subclass of: Functionalization
subclass of: Restriction
  on property: biofunctional
  has value: true
definition: Biofunctionalisation (or biofunctionalization) is the modification of a material to have biological function and/or stimulus, whether permanent or temporary while at the same time being biologically compatible. (wikipedia)
alternative label: Biofunctionalisation

Biologically Active Substance
type: Class
definition: Substance, often a peptide or protein included in a manufactured object in order to impart a biological activity
has alternative id: STY: T123

Biomaterial
type: Class
definition: A non-drug raw material or substance suitable for inclusion in systems which augment or replace the function of bodily tissues or organs
has obo namespace: bcteo
alternative label: Biomaterials

Biomaterial Type
type: Class
description: Classification or nature of biomaterials

Biomineralization
type: Class
subclass of: Mineralization
subclass of: Restriction
  on property: mineralized
  has value: true

Biphasic
type: Class
subclass of: OtherFeatures
definition: Occurring in or characterized by two stages or phases.
has alternative id: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25435

Blend
type: Class
subclass of: Biomaterial Type
description: A mixture of different substances.

Blending
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: blended
  has value: true
has alternative id: The action of mixing or combining substances such as polymers together.

Bonding
type: Class
subclass of: Material Processing
definition: The action of joining things securely by means of adhesive, heat, or pressure or by chemical bonds. There are three primary types of bonding: ionic, covalent, and metallic. (Source: https://depts.washington.edu/matseed/ces_guide/bonding.htm#Metallic)
alternative label: adhesively bonded
alternative label: bonded

Braiding
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: braided
  has value: true
description: In textiles, machine or hand method of interlacing three or more yarns or bias-cut cloth strips in such a way that they cross one another and are laid together in diagonal formation, forming a narrow strip of flat or tubular fabric.

BulkModulus
type: Class
subclass of: MechanicalProperty
has alternative id: bcteo:0000123

CalciumPhosphateCement
type: Class
subclass of: Biomaterial
alternative label: CPC

Casting
type: Class
subclass of: Material Processing
comment: Casting is a manufacturing process in which a liquid material is usually poured into a mold, which contains a hollow cavity of the desired shape, and then allowed to solidify. The solidified part is also known as a casting, which is ejected or broken out of the mold to complete the process. (Wikipedia)

CellAdhesion
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: Cell Attachment

CellEncapsulation
type: Class
subclass of: Encapsulation
alternative label: Microencapsulated Cells

CellHoming
type: Class
subclass of: AssociatedBiologicalProcess
definition: Refers to the ability of cells or exogenously administered cells to locate and enter an environmental niche. From: Liesveld, JL, Sharma, N, Aljitawi, OS. Stem cell homing: From physiology to therapeutics. Stem Cells. 2020; 38: 1241– 1253.

CellularAttachment
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: Cell attachment

CellularDifferentiation
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: Cell Differentiation
alternative label: Differentiation

CellularInfiltration
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: cell infiltration

CellularSpreading
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: Cell Spreading

Ceramic
type: Class
subclass of: Biomaterial Type
description: Inorganic, nonmetallic solid prepared by the action of heat and subsequent cooling. [BCTEO]
has alternative id: http://purl.bioontology.org/ontology/SNOMEDCT/261253002

A representation of a substance using symbols for its constituent elements.
type: Class
subclass of: ChemicalProperty
has alternative id: ncit:C48808

Chemotaxis
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: Chemotactic activity

ChondrogenicDifferentiation
type: Class
subclass of: CellDifferentiation
alternative label: Chondrocyte Differentiation

ChronicInflammation
type: Class
subclass of: InflammatoryReaction
alternative label: chronic inflammatory changes

Coacervation
type: Class
subclass of: Material Processing
definition: Coacervation is a chemical method for producing polymer droplets in suspension based on the separation of two liquid phases into one concentrated colloidal phase, being the coacervate, and another highly dilute colloidal phase. From: Piacentini E. (2016) Coacervation. In: Drioli E., Giorno L. (eds) Encyclopedia of Membranes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44324-8_2019

Coating
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: coated
  has value: true
definition: The application of a thin cover to a material. [CHMO]
has alternative id: http://purl.allotrope.org/ontologies/process#AFP_0001986

ColdAtmosphericPressurePlasmaTreatment
type: Class
subclass of: PlasmaTreatment
alternative label: (CAP) treatment
alternative label: CAP treatment

Collagen
type: Class
subclass of: Biologically Active Substance
has alternative id: CHEBI:3815
has obo namespace: chebi_ontology

Composite
type: Class
subclass of: Biomaterial Type
description: Materials made from two or more constituent materials with significantly different physical or chemical properties, that when combined, produce a material with characteristics different from the individual components. The individual components remain separate and distinct within the finished structure. [BCTEO]
has alternative id: http://purl.obolibrary.org/obo/ID_0000154

Conditioning
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: conditioned
  has value: true

Conductivity
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: conductive
  has value: true

CorrosionBehavior
type: Class
subclass of: OtherFeatures
alternative label: Corrosion

Crosslinking
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: crosslinked
  has value: true
description: The use of cross-links to promote a change in polymers' physical properties.

Crystallinity
type: Class
subclass of: ChemicalProperty
description: The detection and quantification of the amount of amorphous material within a highly crystalline substance.
has alternative id: ncit:C133974

Cytocompatibility
type: Class
subclass of: Effect on Biological System
subclass of: Restriction
  on property: cytocompatible
  has value: true

Cytotoxicity
type: Class
subclass of: AdverseEffects
subclass of: Restriction
  on property: cytotoxic
  has value: true

Decellularization
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: decellularized
  has value: true
description: The physical, chemical and/or enzymatic processing of tissue samples to remove cells and leave behind the extracellular matrix or natural scaffold made up of collagen and other fibers and proteins. [NCIT]
has alternative id: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112947
alternative label: Tissue Decellularization

DecellularizedExtracellularMatrix
type: Class
subclass of: Biomaterial
alternative label: dECM

Degradability
type: Class
subclass of: Degradation Features
subclass of: Restriction
  on property: degradable
  has value: true
alternative label: Degradation

Degradation Features
type: Class
subclass of: Manufactured Object Features
definition: A process or characteristic related to the long term integrity of a manufactured object or its component.

DemineralizedBoneMatrix
type: Class
subclass of: Biologically Active Substance
description: Demineralized allograft bone with osteoinductive activity. Demineralized bone matrices are prepared by acid extraction of allograft bone, resulting in loss of most of the mineralized component but retention of collagen and noncollagenous proteins, including growth factors. The efficacy of a demineralized bone matrix (DBM) as a bone-graft substitute or extender may be related to the total amount of bone morphogenetic protein (BMP) present, and the ratios of the different BMPs present. BMPs belong to the transforming growth factor (TGF) superfamily of proteins.
has alternative id: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61085

DendriticElastinLikePeptides
type: Class
subclass of: Biologically Active Substance
alternative label: Dendritic ELPs

Density
type: Class
subclass of: MechanicalProperty
has alternative id: OPB:00546

DrugDelivery
type: Class
subclass of: Medical Application
alternative label: DrugRelease

Edema
type: Class
subclass of: AdverseEffects
alternative label: Oedema

Effect on Biological System
type: Class
description: Biological effect associated with manufactured object in a specific test system (cells, tissue or organism)

Electrospinning
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: electrospun
  has value: true
description: A process used to created very fine (μm or nm scale) fibres from a liquid. A high voltage is applied to a droplet of the liquid sample which is drawn out into fibres and cooled in air.
has alternative id: http://purl.obolibrary.org/obo/CHMO_0001620

EmulsionSolventEvaporationTechnique
type: Class
subclass of: Emulsion
definition: The emulsion solvent evaporation technique is a method for preparing nanoparticles and nanocapsules that are particularly adapted for applications requiring materials with high purity and low toxicity, such as for biomedicine or electronics. Definition from: Staff et al 2013. Recent Advances in the Emulsion Solvent Evaporation Technique for the Preparation of Nanoparticles and Nanocapsules

Etching
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: etched
  has value: true

Experimental Scaffold
type: Class
subclass of: Manufactured Object
description: A physical object, named by the author of an experimental study, designed and created for in vitro and in vivo evaluation in conjunction with cells or living tissues
alternative label: Scaffold
alternative label: scaffolds

Extrusion
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: extruded
  has value: true

Fiber
type: Class
subclass of: Structure
subclass of: Restriction
  on property: fibrous
  has value: true
alternative label: Fibers
alternative label: Fibre
alternative label: Fibres

Flexibility
type: Class
subclass of: MechanicalProperty
subclass of: Restriction
  on property: flexible
  has value: true

Foaming
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: foamed
  has value: true

ForeignBodyResponse
type: Class
subclass of: AdverseEffects
alternative label: Foreign body

FreezeDrying
type: Class
subclass of: Material Processing
alternative label: freeze-dried
alternative label: freeze-drying

Functionalization
type: Class
subclass of: Coating
subclass of: Restriction
  on property: funcionalized
  has value: true
definition: Functionalization can be the decoration of the scaffold surface with bioactive cues interacting with cells and the ECM to trigger tissue-specific phenotypes. From: Bone Substitute Biomaterials, 2014

Groove
type: Class
subclass of: StructuralDetails
subclass of: Restriction
  on property: grooved
  has value: true
alternative label: grooved

GrowthSubstrate
type: Class
subclass of: Experimental Scaffold
alternative label: substrate

Halofuginone
type: Class
subclass of: Biologically Active Substance
definition: A coccidiostat used in veterinary medicine. Potent type-I collagen inhibitor

Heparin
type: Class
subclass of: Biologically Active Substance
has alternative id: CHEBI:28304
has obo namespace: chebi_ontology

HistologicalExamination
type: Class
subclass of: ResearchTechnique
alternative label: Histological evaluation

Histomorphometry
type: Class
subclass of: ResearchTechnique
alternative label: histomorphometric examination

Hydration
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: hydrated
  has value: true

Hydrogel
type: Class
subclass of: Gel
description: A gel which is primarily composed of a network of polymer chains that are hydrophilic, sometimes found as a colloidal gel in which water is the dispersion medium.
has alternative id: http://purl.bioontology.org/ontology/SNOMEDCT/303529009

Hydrophilicity
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: hydrophilic
  has value: true

Hydrophobicity
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: hydrophobic
  has value: true

Hydroxyapatite
type: Class
subclass of: Biomaterial
alternative label: HA

Immunohistochemistry
type: Class
subclass of: ResearchTechnique
alternative label: Immunohistochemical examination

Immunomodulatory
type: Class
subclass of: Effect on Biological System
alternative label: Immunologic responses

Impermeability
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: impermeable
  has value: true

ImplantRejection
type: Class
subclass of: AdverseEffects
alternative label: Rejection of The Implant

Impregnating
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: impregnated
  has value: true
alternative label: Impregnation

InVitro
type: Class
subclass of: StudyType
alternative label: in-vitro

InVivo
type: Class
subclass of: StudyType
alternative label: in-vivo

InflammatoryReaction
type: Class
subclass of: AdverseEffects
alternative label: Inflammation
alternative label: inflammatory response

IntraperitonealOnlayMesh
type: Class
subclass of: SurgicalProcedure
alternative label: IPOM

Knitting
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: knitted
  has value: true

Lyophilization
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: lyophilized
  has value: true

Macropore
type: Class
subclass of: Pore
subclass of: Restriction
  on property: macroporous
  has value: true

Macroporosity
type: Class
subclass of: Porosity
subclass of: Restriction
  on property: macroporous
  has value: true
description: Has a pore size of at least 50nm

Manufactured Object
type: Class
description: A physical object created by hand or machine
has alternative id: STY: T073

Manufactured Object Component
type: Class
description: A part, region or component referred to as a distinct unit, such as surface, layer etc.

Manufactured Object Features
type: Class
description: Characteristics inherent or given during processing to a manufactured object or its component

Material Processing
type: Class
description: A planned process which results in physical changes in a specified input material.
has alternative id: CHMO:0001267
has alternative id: OBI:0000094

Matrice
type: Class
subclass of: Structure
alternative label: Matrices

MaximumLoad
type: Class
equivalent class: UltimateStrength
subclass of: MechanicalProperty
has alternative id: bcteo:0000173

MaximumStrain
type: Class
subclass of: MechanicalProperty
has alternative id: BCTEO:0000174

MechanicalProperty
type: Class
subclass of: Manufactured Object Features
alternative label: MechanicalProperties

Medical Application
type: Class
description: Intended use, function or outcome of the manufactured object

Medical Device
type: Class
subclass of: Device
description: A device with direct or indirect therapeutic purpose
has obo namespace: sty

MeltBlending
type: Class
subclass of: Material Processing
definition: Melt blending is a simple method for dispersing nanoparticles in a polymer matrix. From: Composites Science and Technology, 2012

Mesoporosity
type: Class
subclass of: Porosity
subclass of: Restriction
  on property: mesoporous
  has value: true
description: Has a pore size between 2-50 nm

Metal
type: Class
subclass of: Biomaterial Type
subclass of: Restriction
  on property: metallic
  has value: true

Microfiber
type: Class
equivalent class: Microfibre
subclass of: Fiber
subclass of: Restriction
  on property: microfibrous
  has value: true

Microgroove
type: Class
subclass of: Groove
subclass of: Restriction
  on property: microgrooved
  has value: true

Microporosity
type: Class
subclass of: Porosity
subclass of: Restriction
  on property: microporous
  has value: true
description: Has a pore size of up to 2 nm

Microtexture
type: Class
subclass of: Texture
subclass of: Restriction
  on property: microtextured
  has value: true

Milling
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: milled
  has value: true

MolarMass
type: Class
subclass of: ChemicalProperty
has alternative id: PATO:0001681
has obo namespace: quality

MolecularStructure
type: Class
subclass of: ChemicalProperty
description: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds
has alternative id: http://purl.bioontology.org/ontology/MESH/D015394

NanoIndentation
type: Class
subclass of: ResearchTechnique
definition: A technique developed in the mid-70s of the last century to measure the elastic modulus, hardness, and fracture toughness of solid materials. From: Membrane Characterization, 2017
alternative label: Instrumented indentation testing
alternative label: nano-indentation

Nanobiocomposite
type: Class
subclass of: Composite
description: Biopolymers formulated and associated with nano-sized fillers, bringing a large range of improved properties (stiffness, permeability, crystallinity, thermal stability).

Nanofibre
type: Class
subclass of: Fiber
subclass of: Restriction
  on property: nanofibrous
  has value: true

Nanoparticle
type: Class
subclass of: Particle
alternative label: NPs

Nanotopography
type: Class
subclass of: Physical Property
alternative label: Nanoscale topography

Neocollagenesis
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: NeoCollagenesis

Neovascularization
type: Class
subclass of: Vascularization
alternative label: Neovasculogenesis

Nonabsorbable
type: Class
subclass of: Degradation Features
subclass of: Restriction
  on property: permanent
  has value: true
alternative label: Non-degradable
alternative label: Nondegradable

OpticalProfilometry
type: Class
subclass of: Profilometry
definition: A technique used to extract topographical data from a surface. This can be done using a physical probe or by using light.

Osteoconductivity
type: Class
subclass of: AssociatedBiologicalProcess
subclass of: Restriction
  on property: osteoconductive
  has value: true
alternative label: Osteoconduction

Osteogenesis
type: Class
subclass of: AssociatedBiologicalProcess
subclass of: Restriction
  on property: osteogenic
  has value: true

OsteogenicDifferentiation
type: Class
subclass of: CellDifferentiation
alternative label: Osteodifferentiation

Osteoinduction
type: Class
subclass of: AssociatedBiologicalProcess
subclass of: Restriction
  on property: osteoinductive
  has value: true
alternative label: osteoinductivity

PCL
type: Class
subclass of: Biomaterial
has obo namespace: chebi_ontology
comment: CHEBI:53200
alternative label: Polycaprolactone

PEG
type: Class
subclass of: Biomaterial
definition: poly(ethylene-glycol)
alternative label: Polyethyleneglycol
alternative label: poly(ethyleneglycol)

PLGA
type: Class
subclass of: Biomaterial
alternative label: Poly D,L lactic co glycolic acid
alternative label: Poly(glycolide:lactide)
alternative label: Polylactide-co-glycolide
alternative label: polylactic-co-glycolic acid

PLLA
type: Class
subclass of: Biomaterial
alternative label: Poly-L-lactic-acid
alternative label: Poly-L-lactide

PS-b-P4VP
type: Class
subclass of: Biomaterial
alternative label: polystyrene-block-poly(4-vinylpyridine)

Perforation
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: perforated
  has value: true

Photocrosslinking
type: Class
subclass of: Crosslinking
subclass of: Restriction
  on property: photocrosslinked
  has value: true
definition: The photoinduced formation of a covalent bond between two macromolecules or between two different parts of one macromolecule. (https://en.wiktionary.org/wiki/photocrosslinking)

Physical Property
type: Class
subclass of: Manufactured Object Features

PickupImpression
type: Class
subclass of: ResearchTechnique
alternative label: Pick up impression technique

PlasmaActivatedChemicalVaporDeposition
type: Class
subclass of: PlasmaTreatment
alternative label: PACVD

PlasmaTreatment
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: plasma treated
  has value: true

PlateletDerivedGrowthFactor
type: Class
subclass of: Biologically Active Substance
alternative label: PDGF

PlateletRichPlasma
type: Class
subclass of: Biologically Active Substance
alternative label: PRP
alternative label: platelet-rich plasma

Polishing
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: polished
  has value: true

Poly-p-dioxanone
type: Class
subclass of: Polydioxanone
has alternative id: CHEBI:61607
alternative label: PPDO

PolyCitricAcid
type: Class
subclass of: Biomaterial
alternative label: poly(citric acid)

PolyGlycerolSebacate
type: Class
subclass of: Biomaterial
alternative label: PGS

PolyLPhenylalanine
type: Class
subclass of: Biomaterial
alternative label: Poly L phenylalanine
alternative label: pPhe

PolyTrimethyleneCarbonate
type: Class
subclass of: Biomaterial
alternative label: PTMC

PolyalphaHydroxyAcid
type: Class
subclass of: SynethticPolymer
alternative label: PHA

Polydioxanone
type: Class
subclass of: Biomaterial
alternative label: PDO
alternative label: PDS
alternative label: PDX
alternative label: Polidioxanone
alternative label: Polydioxanon
alternative label: p-dioxanone
alternative label: poly(dioxanone)
alternative label: poly-dioxanone

Polydopamine
type: Class
subclass of: Biomaterial
comment: PDA

Polyetherurethane
type: Class
subclass of: Biomaterial
alternative label: PEU

PolyethyleneTerephthalate
type: Class
subclass of: Biomaterial
alternative label: Dacron
alternative label: Mersilene

Polyethylenimine
type: Class
subclass of: Biomaterial
alternative label: PEI

Polyglactin910
type: Class
subclass of: Biomaterial
alternative label: PG910

PolyglycolicAcid
type: Class
subclass of: Biomaterial
alternative label: Dexon
alternative label: PGA

Polylacticacid
type: Class
subclass of: Biomaterial
alternative label: PLA
alternative label: Poly L lactide
alternative label: Poly lactic acid
alternative label: poly(d,l-lactic acid)

Polylysine
type: Class
subclass of: Biomaterial
alternative label: Poly L lysine
alternative label: pLys

Polymer
type: Class
subclass of: Biomaterial Type
subclass of: Restriction
  on property: polymeric
  has value: true
alternative label: Polymers
alternative label: polymeric

Polymerization
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: polymerized
  has value: true

Polytetrafluoroethylene
type: Class
subclass of: Biomaterial
alternative label: PTFE
alternative label: Teflon

PolyvinylideneFluoride
type: Class
subclass of: Biomaterial
alternative label: PVDF
alternative label: polyvinylidene difluoride

Porosity
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: porous
  has value: true

Powder
type: Class
subclass of: Structure
subclass of: Restriction
  on property: powdered
  has value: true

Precoating
type: Class
subclass of: Coating
subclass of: Restriction
  on property: precoated
  has value: true

Preconditioning
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: preconditioned
  has value: true

QuartzCrystalMicrobalanceTechnique
type: Class
subclass of: ResearchTechnique
definition: The use of a quartz crystal microbalance for measuring weights and forces in the micro- to nanogram range. It is used to study the chemical and mechanical properties of thin layers, such as polymer coatings and lipid membranes; and interactions between molecues. (from: MESH)
has alternative id: http://purl.bioontology.org/ontology/MESH/D058525
has alternative id: http://purl.obolibrary.org/obo/CHMO_0001077
alternative label: Quartz crystal microbalance

RadialCompressiveStrength
type: Class
subclass of: MechanicalProperty
alternative label: Radial compression strength

RapidPrototyping
type: Class
subclass of: Material Processing
definition: Rapid prototyping is a group of techniques used to quickly fabricate a scale model of a physical part or assembly using three-dimensional computer aided design (CAD) data (Wikipedia).

RecombinantHumanBoneMorphogeneticProtein
type: Class
subclass of: BMP
alternative label: rhBMP

RecombinantHumanPlateletDerivedGrowthFactor
type: Class
subclass of: PlateletDerivedGrowthFactor
alternative label: rhPDGF

Reinforcement
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: reinforced
  has value: true

Reinnervation
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: re-innervation

ResearchTechnique
type: Class
description: A laboratory or clinical technique used to evaluate a biomaterial (or implant/device) and their effect.

Resorption
type: Class
subclass of: Degradation Features
subclass of: Restriction
  on property: resorbable
  has value: true

Roughening
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: roughened
  has value: true

Sandblasting
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: sandblasted
  has value: true

ScanningElectronMicroscopy
type: Class
subclass of: ResearchTechnique
alternative label: SEM

SelfAssembling
type: Class
subclass of: OtherFeatures
alternative label: self-assembling

SelfExpanding
type: Class
subclass of: OtherFeatures
comment: self-expanding

Semipermeablity
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: semipermeable
  has value: true
alternative label: semi-permeable

Shape
type: Class
subclass of: Manufactured Object Features
definition: The external form, contours, or outline of a manufactured object or a component

Siderophore
type: Class
subclass of: Biologically Active Substance
has alternative id: CHEBI:26672
has alternative id: http://purl.obolibrary.org/obo/CHEBI_26672

Sintering
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: sintered
  has value: true

SmallCaliber
type: Class
subclass of: Size
alternative label: small-caliber

Sol-gel
type: Class
subclass of: Material Processing
description: The process of the settling of (nm sized) particles from a colloidal suspension onto a pre-existing surface, resulting in ceramic materials. The desired solid particles (e.g. metal alkoxides) are suspended in a liquid, forming the 'sol', which is deposited on a substrate by spinning, dipping or coating, or transferred to a mould. The particles in the sol are polymerised by partial evaporation of the solvent, or addition of an initiator, forming the 'gel', which is then heated at high temperature to give the final solid product.
has alternative id: http://purl.obolibrary.org/obo/CHMO_0001313
alternative label: sol–gel method

Sponge
type: Class
subclass of: Structure
subclass of: Restriction
  on property: spongy
  has value: true

SprayDrying
type: Class
subclass of: Material Processing
definition: A method of producing a dry powder from a liquid or slurry by rapidly drying with a hot gas. This is the preferred method of drying of many thermally-sensitive materials such as foods and pharmaceuticals (wikipedia).
alternative label: spray-drying

Structure
type: Class
subclass of: Manufactured Object Features
description: The structure, form or texture associated with a manufactured object or its components.

StudyType
type: Class
description: The set-up of the study (in vitro, in vivo, etc)

SurfaceHydrophilicity
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: hydrophilic
  has value: true

SurgicalImplant
type: Class
subclass of: Manufactured Object
alternative label: Implant

TensileStrength
type: Class
equivalent class: UltimateStrength
subclass of: MechanicalProperty
alternative label: Mechanical strength

Texture
type: Class
subclass of: Physical Property
subclass of: Restriction
  on property: textured
  has value: true

TiO2
type: Class
subclass of: Biomaterial
alternative label: Titania
alternative label: Titanium dioxide
alternative label: Titanium(IV) oxide

TissueReconstruction
type: Class
subclass of: Medical Application
alternative label: TissueAugmentation

Titanium
type: Class
subclass of: Biomaterial
alternative label: Ti

TitaniumAluminiumNitride
type: Class
subclass of: Biomaterial
alternative label: TiAlN

Titaniumcarboxonitride
type: Class
subclass of: Biomaterial
alternative label: [Ti(C,N,O)]

Toxicity
type: Class
subclass of: AdverseEffects
subclass of: Restriction
  on property: toxic
  has value: true

Transparent
type: Class
subclass of: Physical Property
alternative label: Transparancy

Tube
type: Class
subclass of: Structure
alternative label: tubes

TypeICollagen
type: Class
subclass of: Collagen
alternative label: collagen (Type I)

Vascularization
type: Class
subclass of: AssociatedBiologicalProcess
alternative label: Vascularisation

WaterInOilInWaterDoubleEmulsion
type: Class
subclass of: Emulsion
alternative label: water-in-oil-in-waterdouble-emulsion

Weaving
type: Class
subclass of: Material Processing
subclass of: Restriction
  on property: woven
  has value: true

bioprinting
type: Class
subclass of: Printing
subclass of: Restriction
  on property: bioprinted
  has value: true

nanostructure
type: Class
subclass of: Structure
subclass of: Restriction
  on property: nanostructured
  has value: true

3DPrinting
type: Class
subclass of: Printing
subclass of: Restriction
  on property: 3D printed
  has value: true
alternative label: Three dimensional printing

Poly(2-hydroxyethylMethacrylate)
type: Class
subclass of: Biomaterial
alternative label: Polyhydroxyethylmethacrylate
alternative label: pHEMA

Poly(N-(2-Hydroxypropyl)methacrylamide)
type: Class
subclass of: Biomaterial
alternative label: Poly(HPMA)
alternative label: pHPMA

Poly(N-acryloyl glycinamide)
type: Class
subclass of: Biomaterial
alternative label: PNAGA

Poly(N-isopropylacrylamide)
type: Class
subclass of: Biomaterial
alternative label: PNIPA
alternative label: PNIPAM

Poly(ethylene-vinyl acetate)
type: Class
subclass of: Biomaterial
alternative label: Ethylene-vinyl acetate
alternative label: PEVA

Poly(glycolide-co-epsilon-caprolactone)
type: Class
subclass of: Biomaterial
alternative label: PGACL

Poly(vinyl alcohol)
type: Class
subclass of: Biomaterial
alternative label: PVA
alternative label: Poly vinyl alcohol